model_p beta_cntot stde_cntot t_val_cntot pval_cntot beta_loh stde_loh tval_loh pval_loh gene class fdr_model fdr_loh fdr_cntot ass_coeff_CN ass_coeff_LOH 2.44614332406492e-52 196.816413060409 11.3542265351995 17.3341981904494 1.46821436347595e-53 138.262860979369 90.0657347252515 1.53513277164889 0.125353619359002 DPM1 other 3.71495786625739e-48 1 2.25826051246236e-49 17.3341981904494 1.53513277164889 7.27439348759275e-16 128.619829679341 15.352661613333 8.37768934916416 4.63421067426101e-16 -153.793757021168 113.425848647644 -1.35589690405515 0.17569557299069 SCYL3 other 7.7254058838235e-12 1 6.03652282429239e-12 8.37768934916416 -1.35589690405515 4.72882514108798e-16 90.1449039017084 10.4998039422015 8.58538925087852 9.54064181178608e-17 -50.0149072183617 79.4340273699691 -0.629640833712409 0.529193945771013 C1orf112 other 5.04754795559731e-12 1 1.25841065497458e-12 8.58538925087852 -0.629640833712409 0.298093093260697 -7.04906931245939 13.6467869400401 -0.516536921359649 0.605689754468434 -32.4914303691192 21.3579652594367 -1.52127929671406 0.128771850594447 FGR other 1 1 1 -0.516536921359649 -1.52127929671406 0.469725980643707 9.86534856354853 42.2774954345776 0.233347516501177 0.815580984771497 -348.118330948221 293.136060083801 -1.18756570190888 0.235532522651258 CFH other 1 1 1 0.233347516501177 -1.18756570190888 2.72266872375777e-25 364.696689041841 40.8402913515752 8.92982584042645 6.90635866762776e-18 -154.56228430883 89.1559676288321 -1.7336168112974 0.0835643716290279 FUCA2 other 3.5304845340967e-21 1 9.27523969062409e-14 8.92982584042645 -1.7336168112974 0.000156176314759865 54.4741844805016 37.5500464071974 1.45070884573022 0.147461579293591 -458.361084047049 137.755960872819 -3.32734119919662 0.000938586939210445 GCLC other 0.828202997171565 1 1 1.45070884573022 -3.32734119919662 1.81296164234097e-52 441.196240815015 26.9626594147308 16.3632316096376 3.22019099154396e-49 -145.568724036259 121.964744793214 -1.19353116577307 0.233182601506042 NFYA other 2.75425132704441e-48 1 4.93075644625211e-45 16.3632316096376 -1.19353116577307 1.65018501319245e-30 70.265080567203 9.41080010925567 7.46643003267026 3.27145382323584e-13 -77.9706731686894 15.9297636212466 -4.8946534940854 1.2978055107169e-06 STPG1 other 2.26817930063303e-26 0.0163962203008417 4.0255239294917e-09 7.46643003267026 -4.8946534940854 4.51540323701595e-08 135.341046749073 64.788810827612 2.08895710571358 0.0371748898094292 -409.070523717194 109.134978943267 -3.74829892009093 0.000197049890313262 NIPAL3 other 0.000334817150024733 1 1 2.08895710571358 -3.74829892009093 1.36226995537866e-37 509.662129371546 36.386509902658 14.0068979062572 4.03197434830075e-38 268.228877343947 170.938857441453 1.5691509897673 0.117212958464838 ENPP4 other 1.97283934937937e-33 1 6.06812139419263e-34 14.0068979062572 1.5691509897673 6.92280086455903e-23 238.917641529793 123.229755964693 1.93879830126619 0.0530604315847187 -1866.64218760201 226.424420194636 -8.2439967650019 1.33743224494782e-15 SEMA3F other 8.65903932139044e-19 2.01778402795278e-11 1 1.93879830126619 -8.2439967650019 0.548419303318692 3.86470072176 9.80057909053301 0.394333914971734 0.693490498257622 33.1878991824573 30.2908005951544 1.09564285295801 0.273724412204369 CFTR other 1 1 1 0.394333914971734 1.09564285295801 2.09805258082417e-09 219.551544712631 50.8594808427146 4.31682630405931 1.87984165812115e-05 -585.170609779501 168.601651335463 -3.47072881638153 0.000560100825624031 ANKIB1 other 1.69103038014428e-05 1 0.165520057997567 4.31682630405931 -3.47072881638153 1.21449165263019e-05 338.185553736299 104.368781339569 3.24029417030363 0.00126677262374329 -889.736314148838 345.987583635389 -2.57158451988401 0.0103868903497629 CYP51A1 other 0.0732702814031791 1 1 3.24029417030363 -2.57158451988401 2.67912930022126e-13 88.1963734266262 18.8791794160783 4.67162112732052 3.76750160575705e-06 -301.153688635917 62.5853975044113 -4.81188425166893 1.937494785571e-06 KRIT1 other 2.5923255108941e-09 0.0242806846527757 0.0349624149014255 4.67162112732052 -4.81188425166893 6.66902272525847e-42 49.6251749973213 3.69032393922951 13.4473763860639 1.31549223635763e-35 -53.6335906156489 14.7908892021864 -3.62612347929161 0.000315932480198643 RAD52 other 9.84814585838919e-38 1 1.96889723015647e-31 13.4473763860639 -3.62612347929161 9.13219444695759e-05 85.6040658540951 43.1774831821832 1.98260897915001 0.0479270139998012 -280.483009663999 102.708951764827 -2.73085261649074 0.00652746231578543 BAD other 0.498891782637293 1 1 1.98260897915001 -2.73085261649074 5.70018191108337e-08 522.685730766028 104.17781664418 5.0172459704283 7.10576103614401e-07 -43.18239353005 199.465226083192 -0.216490835911617 0.828686176913802 LAP3 other 0.00042050241958062 1 0.00690040454219945 5.0172459704283 -0.216490835911617 0.00131618138435624 4.48157241023088 8.39114262724575 0.534083689112776 0.593503020388669 54.5516159174561 15.9204541378221 3.42651129454016 0.00065786099139429 HS3ST1 other 1 1 1 0.534083689112776 3.42651129454016 0.522273741445672 26.527206988704 40.7471338801703 0.651020193634124 0.515307333165461 -83.897722417496 126.312862737981 -0.664205692111739 0.506839059869359 AOC1 other 1 1 1 0.651020193634124 -0.664205692111739 0.72758147964583 0.608196668642331 1.766924852518 0.344211961123081 0.730818931244929 5.36957983367643 6.88995377881683 0.779334666973414 0.436119022388972 HECW1 other 1 1 1 0.344211961123081 0.779334666973414 7.3547946147884e-09 79.0803508736691 17.4269353800056 4.53782315417318 7.03794144683859e-06 -174.425666090521 59.3891903151559 -2.93699350277231 0.00345820203053903 MAD1L1 other 5.73968171738087e-05 1 0.0641297224635933 4.53782315417318 -2.93699350277231 2.82817402634558e-83 3207.54939092907 142.418955446647 22.521927512175 1.29068989002913e-78 -4072.87559184605 1065.45122316682 -3.82267672445889 0.000148226845043718 LASP1 other 4.40261850681217e-79 1 2.00895881383034e-74 22.521927512175 -3.82267672445889 1.25446997660174e-75 125.163878560835 6.74248544371128 18.5634629256153 1.24139026163626e-59 -175.215816092306 25.3145844142119 -6.92153634542537 1.29518992374215e-11 SNX11 other 1.94656106269292e-71 1.87802538942612e-07 1.91745139812337e-55 18.5634629256153 -6.92153634542537 0.350140604910705 -2.50398616631849 70.8426537287524 -0.0353457420709554 0.971816967214929 -302.568772830074 219.60657215179 -1.37777649305023 0.168836728327436 TMEM176A other 1 1 1 -0.0353457420709554 -1.37777649305023 6.84004816197072e-39 583.44480417787 46.7877842901915 12.4700242387879 1.37712417147373e-31 -525.293959661016 156.218721102641 -3.36255447460667 0.000826262072550142 M6PR other 9.96731818162373e-35 1 2.0363535123582e-27 12.4700242387879 -3.36255447460667 0.11039560681522 30.3532568300071 16.0712587273529 1.88866705122148 0.0594672028230263 65.9992593110557 54.5584614260284 1.20969795676036 0.226919270072676 CYP26B1 other 1 1 1 1.88866705122148 1.20969795676036 5.30179925539667e-20 175.242069820612 37.5848224251077 4.66257543639598 3.93358460439195e-06 -966.926407104912 134.733323273951 -7.17659435401051 2.35395902853525e-12 ICA1 other 6.27892085816628e-16 3.4461960177756e-08 0.0364525285289002 4.66257543639598 -7.17659435401051 7.79116020531442e-36 334.584194456021 57.2269564515463 5.84661871262211 8.83159757564799e-09 -746.208746752718 123.950353543026 -6.02022281843425 3.2778040042623e-09 DBNDD1 other 1.11842104747288e-31 4.53779186350072e-05 9.47012208036734e-05 5.84661871262211 -6.02022281843425 2.96466507116605e-16 114.456711413223 18.4656423057797 6.19836069159631 1.12950417447745e-09 -193.703887739103 45.393945216508 -4.2671745497164 2.33593793254422e-05 ALS2 other 3.18612555198215e-12 0.275313644729662 1.254766187427e-05 6.19836069159631 -4.2671745497164 0.0561407959285042 31.7080311483345 15.4853792288866 2.04761089022515 0.0410804921135386 -27.2603246355731 38.5041641278717 -0.707983805207199 0.479260216202324 CASP10 other 1 1 1 2.04761089022515 -0.707983805207199 7.38391791614749e-06 312.2884166325 73.790911526386 4.23207154069147 2.72159187705748e-05 -259.817241116706 183.922638162836 -1.41264416230631 0.158337516404123 CFLAR other 0.0454110951843071 1 0.236696845547689 4.23207154069147 -1.41264416230631 0.380503061090666 -13.7900906413518 73.544198312784 -0.187507525511428 0.851334215369401 -261.149764675607 189.068245976905 -1.38124603275532 0.167783189925229 TFPI other 1 1 1 -0.187507525511428 -1.38124603275532 7.86584983518863e-21 69.1500065572071 6.96011318272495 9.93518420488303 1.7601254442776e-21 11.1637195418112 22.1331527557762 0.504389034178501 0.614193004826016 NDUFAF7 other 9.47520271146822e-17 1 2.45238278151197e-17 9.93518420488303 0.504389034178501 2.38310828323274e-37 12.7367392418883 66.3447834583137 0.191978006076259 0.847833522756398 -1499.28297039485 121.903017740223 -12.2989815854259 9.85542305614239e-31 RBM5 other 3.44692782086783e-33 1.54257081674741e-26 1 0.191978006076259 -12.2989815854259 1.97105523432666e-09 28.2705204194284 6.5438155409627 4.32018907661162 1.85700856190601e-05 -13.417085428346 13.3799048083092 -1.00277884040055 0.316418378048826 MTMR7 other 1.59082376488947e-05 1 0.16360245430392 4.32018907661162 -1.00277884040055 7.46255775085726e-10 463.176925837364 743.045510531006 0.623349336309645 0.533318660365553 -7170.92789344153 1517.78275631682 -4.72460756560649 2.94529786529303e-06 SLC7A2 other 6.15213260980673e-06 0.0366041618698618 1 0.623349336309645 -4.72460756560649 1.57294719597372e-17 564.319049947857 99.7484929111561 5.65741931008907 2.48660431444074e-08 -1492.1241139563 307.678535955834 -4.8496204303653 1.61703521636379e-06 ARF5 other 1.75320694463231e-13 0.020335834880991 0.000261938898483188 5.65741931008907 -4.8496204303653 8.46146796204875e-23 221.976247179115 31.394765169908 7.07048598636692 5.12103307361136e-12 -595.948009476299 116.052632872861 -5.13515285886857 4.02084985559931e-07 SARM1 other 1.05751426589685e-18 0.00519011299360758 6.12270714280974e-08 7.07048598636692 -5.13515285886857 7.35220504800711e-83 918.034979181774 42.1247483061604 21.7932454458729 7.14767862322856e-75 -246.698482106906 155.71665924491 -1.5842780297444 0.113751536573172 POLDIP2 other 1.14437071572231e-78 1 1.11153550269827e-70 21.7932454458729 -1.5842780297444 3.98424388952372e-05 641.665578944703 153.175565455882 4.18908575290697 3.2729774197058e-05 -472.560939962199 494.402433670774 -0.955822438926102 0.339591233779742 PLXND1 other 0.228257332430814 1 0.28301435748196 4.18908575290697 -0.955822438926102 6.54103711524038e-16 517.820563444406 81.4871795930956 6.35462616365091 4.43920446769106e-10 -411.069387800915 151.65988749196 -2.71046876401454 0.00693212712950301 AK2 other 6.95900938690424e-12 1 5.01141792357644e-06 6.35462616365091 -2.71046876401454 0.00067520340782757 16.335930354985 11.9506133229903 1.36695330302071 0.172204549926994 86.9103826408975 22.8298714399586 3.80687131197682 0.000156738310603322 CD38 other 1 1 1 1.36695330302071 3.80687131197682 3.81715259486122e-30 2177.68951207075 213.830261253802 10.1841970322713 2.18472436334987e-22 -4161.86680189285 932.525505421115 -4.46300586707643 9.85632663274596e-06 FKBP4 other 5.22797219392193e-26 0.119044713070306 3.06735300614322e-18 10.1841970322713 -4.46300586707643 5.29902707315799e-17 518.142882843831 88.0724296927882 5.88314509604428 7.02426690343294e-09 -362.379517240142 138.629148493202 -2.61402108560101 0.00919531575743504 KDM1A other 5.82045133715674e-13 1 7.56794516175865e-05 5.88314509604428 -2.61402108560101 9.89499007766722e-25 182.467443532966 48.8836908196686 3.73268549230635 0.000210095628177562 -663.888944846114 89.61337274132 -7.40836913662999 5.12572957682099e-13 RBM6 other 1.27397997249965e-20 7.55430025031877e-09 1 3.73268549230635 -7.40836913662999 1.44585434878266e-28 78.2232341508988 12.3690484174438 6.32411091871727 5.28985254784516e-10 -152.497046106879 22.789031249931 -6.69168620791376 5.46253310099884e-11 CAMKK1 other 1.95103585824732e-24 7.84201251979394e-07 5.95055513107102e-06 6.32411091871727 -6.69168620791376 5.57537541887332e-34 333.671533398385 26.9492474486443 12.3814787048968 4.25415324928758e-31 -90.1124446328469 94.6253051819554 -0.952308100455467 0.341375661906945 RECQL other 7.89361651804084e-30 1 6.28083185724818e-27 12.3814787048968 -0.952308100455467 7.51724549698638e-05 40.3965996204212 33.0212629806028 1.22335113723999 0.22172869837675 -394.578808490028 105.575722401913 -3.73740098114526 0.000205674422536388 VPS50 other 0.415628503528377 1 1 1.22335113723999 -3.73740098114526 0.731845066727588 64.2528700715649 153.533675402297 0.418493662079058 0.675751079404964 -404.368826222918 705.142173898687 -0.5734571568556 0.566571747786386 HSPB6 other 1 1 1 0.418493662079058 -0.5734571568556 0.000234728142845999 37.9061793284211 13.4809986335272 2.81182280028933 0.00510359987927673 -147.917708646828 61.9148903839005 -2.38904902729652 0.0172311733791888 ARHGAP33 other 1 1 1 2.81182280028933 -2.38904902729652 1.07118840267381e-26 275.116370869157 25.0650732592484 10.9760848501668 1.93505565965833e-25 -105.411451948155 137.248192396627 -0.768035265947489 0.442801953413008 NDUFAB1 essential 1.41611106833478e-22 1 2.77796590500549e-21 10.9760848501668 -0.768035265947489 0.66087214661088 191.800728365917 248.267086719532 0.772558017658598 0.4401232510851 -201.786896363103 793.17481101064 -0.254404065234992 0.799280617678244 PDK4 other 1 1 1 0.772558017658598 -0.254404065234992 1.7213148664082e-21 -2.9193337065906 29.0894016306053 -0.100357296573579 0.920098982566615 -482.853862032966 53.4987695640203 -9.02551340839999 3.37826935942615e-18 ZMYND10 other 2.09862708512487e-17 5.16976560072984e-14 1 -0.100357296573579 -9.02551340839999 0.632820559979563 -0.817261281652282 1.22517852000588 -0.667054856339105 0.505020971017096 -4.50820438534448 5.49063479975054 -0.821071615535113 0.411966466221176 ABCB5 other 1 1 1 -0.667054856339105 -0.821071615535113 2.66677003732632e-13 131.725154106855 20.7298382592685 6.35437442682215 4.46982739671492e-10 -176.509594872121 66.2217302087759 -2.66543314884166 0.00792039308464751 SLC25A13 other 2.58116671912814e-09 1 5.04464719993245e-06 6.35437442682215 -2.66543314884166 4.4379910484955e-36 358.341760939898 31.9708562314392 11.2083879876672 2.59346853687706e-26 -245.249759020785 78.3532269722453 -3.13005307500173 0.00184404402514772 CDC27 essential 6.37783693579288e-32 1 3.74315313927466e-22 11.2083879876672 -3.13005307500173 0.249801661733416 14.327712147001 9.18593103351916 1.55974523374057 0.119404858259262 -4.33985270301118 29.3639140523687 -0.147795443593498 0.882559271248451 CALCR other 1 1 1 1.55974523374057 -0.147795443593498 6.89816334671853e-29 162.096907791529 20.6081749032677 7.86566052318522 2.01224699933065e-14 -188.488594038696 37.5091147597688 -5.02514109559481 6.85082053766977e-07 DVL2 other 9.34494188579959e-25 0.00876425471384094 2.5426753083542e-10 7.86566052318522 -5.02514109559481 2.6748520280622e-10 62.7278008516868 10.7193317436538 5.85183874814061 8.41324777032167e-09 -61.4652347156892 48.7929233445785 -1.25971617403651 0.208312932427615 PRSS22 other 2.25918002290133e-06 1 9.03162148144031e-05 5.85183874814061 -1.25971617403651 4.24031923951791e-23 497.40173236914 58.5751421953049 8.49168629775873 1.99587588740529e-16 -728.793968922725 195.136306717528 -3.73479431471305 0.00020791498191163 UPF1 essential 5.32202467751893e-19 1 2.61639370079959e-12 8.49168629775873 -3.73479431471305 0.00224398596370711 74.7963797324932 21.729934050991 3.44208958743168 0.000622054390601218 -18.1719416724813 110.991950748787 -0.163723058743338 0.870010535586974 SKAP2 other 1 1 1 3.44208958743168 -0.163723058743338 0.0068052878535465 44.1506167644228 18.9164980717775 2.33397411068878 0.0199616128211304 -42.0837794279254 41.4291987806906 -1.01579998326059 0.310177869954597 MCUB other 1 1 1 2.33397411068878 -1.01579998326059 0.100702819640727 4.07806804538534 3.00682488087595 1.35627055347411 0.175599437687462 23.6355400048487 12.5950291953186 1.87657683347282 0.0611337481777374 HOXA11 og 1 1 1 1.35627055347411 1.87657683347282 5.61911677800614e-13 124.971356699174 27.8795888062171 4.48253945091563 9.01214154386489e-06 -406.42130490523 86.7472195966235 -4.68512197618665 3.54544284150833e-06 POLR2J essential 5.35558020111765e-09 0.0438571279494581 0.0815238324058018 4.48253945091563 -4.68512197618665 3.1043076644651e-30 203.319317387267 19.1343999822552 10.6258527874311 4.23383560226961e-24 -50.5951703015238 34.798508127351 -1.45394653461471 0.146535685781807 DHX33 essential 4.25569537721521e-26 1 6.03025204831261e-20 10.6258527874311 -1.45394653461471 0.0388088298703328 -17.3273192249469 13.0864480708898 -1.32406586807086 0.186044475421424 -73.8267870627118 29.1178853521876 -2.5354446646712 0.0115129962732071 MEOX1 other 1 1 1 -1.32406586807086 -2.5354446646712 0.330905070719885 -9.58436612440392 8.73933507457268 -1.09669283104728 0.273263610658605 -39.1831487636925 31.4505474738155 -1.24586539538985 0.213353076547653 THSD7A other 1 1 1 -1.09669283104728 -1.24586539538985 3.61908250208164e-58 503.023807241045 35.8749377487393 14.0215938704652 3.09473373451976e-38 -433.528362226583 84.2580082022824 -5.14524816662875 3.76384229699374e-07 LIG3 other 5.54805347569115e-54 0.00486438978463471 4.65943111069295e-34 14.0215938704652 -5.14524816662875 3.1197954750482e-17 116.13283850431 16.6540118980492 6.9732650135739 9.13246053700647e-12 -177.269978258593 48.4349812222139 -3.65995761297603 0.000277175967473373 RPAP3 essential 3.4501818158558e-13 1 1.08493631179637e-07 6.9732650135739 -3.65995761297603 2.10496215292522e-05 32.1181430844812 7.63215533441875 4.20826643027533 3.0084810747029e-05 -36.2325643707452 40.5223466500399 -0.894137861354816 0.371642092967544 ACSM3 other 0.124108568536471 1 0.261106072473465 4.20826643027533 -0.894137861354816 6.09458021676821e-83 274.257222262203 20.2307544975614 13.556450516725 2.76258797561832e-36 -312.505254899393 44.0025292167037 -7.10198391915989 3.85870014832423e-12 CIAPIN1 essential 9.48682356542139e-79 5.63215873649405e-08 4.14250066943967e-32 13.556450516725 -7.10198391915989 8.18614220976203e-11 55.1314780473336 48.1468406784815 1.14506948473514 0.252696212826848 -506.28092878401 91.4063852941126 -5.53879170645444 4.79786610630394e-08 SPPL2B other 7.0932922247588e-07 0.000641714591718152 1 1.14506948473514 -5.53879170645444 1.12937623658446e-10 63.1666876076968 13.8535493972795 4.5596031599022 6.35575511888933e-06 -130.690837499561 36.4748765872096 -3.58303714029259 0.000370574695744138 FAM214B other 9.71376501086292e-07 1 0.0581043132968863 4.5596031599022 -3.58303714029259 0.0141554387854341 20.4550526801119 12.7887433320811 1.59945759711977 0.110318271132554 -80.5435445076467 41.4041316114636 -1.94530210809557 0.0522700326568674 COPZ2 other 1 1 1 1.59945759711977 -1.94530210809557 0.0329896592109015 320.468340972894 136.341947087644 2.35047502121184 0.0191069439294054 -147.995565942138 404.589599908551 -0.365791819600873 0.714663144814338 PRKAR2B other 1 1 1 2.35047502121184 -0.365791819600873 2.84286683592256e-12 385.142540524538 61.7214891529604 6.24000726181547 8.82748435506684e-10 -546.048356919473 289.101171639896 -1.88877946713972 0.0594550390243512 CREBBP og 2.64045471720487e-08 1 9.84882429494807e-06 6.24000726181547 -1.88877946713972 2.32628252342259e-07 60.7915403193367 15.4658644801195 3.93069138795836 9.61364114080309e-05 -213.247637763463 68.3964898083474 -3.11781552475866 0.00192262645569441 TSPOAP1 other 0.00163700501173248 1 0.795721077224272 3.93069138795836 -3.11781552475866 1.37785533269042e-05 57.9157468181147 13.5896284361169 4.2617608781851 2.39137539424543e-05 -71.9344622743407 46.7355663759878 -1.53918028286269 0.124342796553433 GCFC2 other 0.0827815483880404 1 0.208982295703108 4.2617608781851 -1.53918028286269 0.00769317585205299 39.6073494980067 15.9925250352756 2.4766163823813 0.0135680819807517 -83.9058741135054 54.7290195981081 -1.53311487634261 0.125832104553444 WDR54 other 1 1 1 2.4766163823813 -1.53311487634261 3.49322204230926e-05 -16.9420632664577 42.1518297173089 -0.401929486337358 0.68789436467072 -616.076421146138 136.703724714408 -4.50665424393668 8.0737552325463e-06 CROT other 0.201314386298283 0.0980315360335771 1 -0.401929486337358 -4.50665424393668 0.0958613847473949 0.0136424645393917 2.59630469382825 0.00525456991693678 0.995809412490733 -17.6516793389092 8.42014509263588 -2.09636284704251 0.0365130287210059 ABCB4 other 1 1 1 0.00525456991693678 -2.09636284704251 7.66339643504306e-07 50.6479534201332 57.3620904946815 0.882951666917182 0.377653109609624 -829.538067636833 174.087938688803 -4.76505192654217 2.42694594919205e-06 KMT2E other 0.00517355893329757 0.0302979932297136 1 0.882951666917182 -4.76505192654217 2.60029576754978e-10 226.248566451533 76.0368769282581 2.97551103611215 0.00305795370241471 -1413.72213424804 269.011823139363 -5.25524163863852 2.14324466342162e-07 RHBDD2 other 2.1993301601936e-06 0.00279371941877008 1 2.97551103611215 -5.25524163863852 9.32223602310438e-05 53.9240992432624 24.5750683555118 2.19426039688586 0.028643509777417 464.850796185316 108.774934022008 4.27351025642787 2.27605777984513e-05 SOX8 other 0.508527975060344 0.268597578599523 1 2.19426039688586 4.27351025642787 1.67265628711998e-11 71.8341267444971 55.1313261600353 1.30296388184055 0.19314760804098 -643.822310906168 120.723799663369 -5.33301894656587 1.42757529367325e-07 IBTK other 1.49853276763079e-07 0.00187754702623906 1 1.30296388184055 -5.33301894656587 1.82068407576223e-15 75.0516245261756 14.7733107306315 5.08021701395347 5.20459357601892e-07 -129.115816545327 31.2634427081477 -4.12992957143768 4.20512540861048e-05 ZNF195 other 1.90771277458367e-11 0.487374034857955 0.00509841986706813 5.08021701395347 -4.12992957143768 4.70388717619109e-06 230.130662121847 85.4773427016981 2.69230014467068 0.00732446973860662 -449.783890586656 171.38624123393 -2.62438739159191 0.00893523741228232 MYCBP2 other 0.0294557414973086 1 1 2.69230014467068 -2.62438739159191 2.25587184319371e-25 159.014858966773 59.3079870431798 2.68117106808903 0.00756863904295748 -1028.93395302122 118.739317582121 -8.66548649573974 5.66279557892769e-17 FBXL3 other 2.92970076275567e-21 8.61367835510691e-13 1 2.68117106808903 -8.66548649573974 2.7231527916792e-10 133.183345376415 19.7667969501526 6.73773023076389 4.21887683975907e-11 112.005449574307 120.192765718951 0.931881789260194 0.351823522792274 ITGAL other 2.29888558673558e-06 1 4.90992886611161e-07 6.73773023076389 0.931881789260194 1.10669413488175e-37 183.86337833871 16.1741831892216 11.3677071780191 6.51662473630902e-27 -459.692120739306 77.367086150587 -5.9417013566281 5.1527969879188e-09 PDK2 other 1.60326779320319e-33 7.10055424935211e-05 9.43542095570183e-23 11.3677071780191 -5.9417013566281 8.60231680090527e-18 443.165802137508 58.6297717419459 7.55871614319198 1.85162010511104e-13 -990.706678516888 273.146145888087 -3.62702052886661 0.000314976035046943 ITGA3 other 9.66298246245689e-14 1 2.29249085213798e-09 7.55871614319198 -3.62702052886661 6.98070127470954e-07 10.245883989299 1.90043544835793 5.39133491650659 1.04850010230314e-07 10.3895574086667 4.4356191649573 2.34230149665401 0.0195288911380272 ITGA2B other 0.00472942511361572 1 0.00106905070430828 5.39133491650659 2.34230149665401 1.01028285156961e-25 465.845069701239 49.6955880851194 9.37397237161841 1.82961589785028e-19 -940.572118780727 263.452696019323 -3.57017458159448 0.000388144292717495 GDE1 other 1.31831809301318e-21 1 2.50199974031026e-15 9.37397237161841 -3.57017458159448 2.94143531489529e-08 316.230496301023 56.774974592861 5.56989234374376 4.02809438568269e-08 687.86230998172 186.916041742857 3.68006032851916 0.000256620053627499 CRLF1 other 0.000221372421799019 1 0.000420130244426704 5.56989234374376 3.68006032851916 5.34799650552454e-17 35.8115551850468 6.58079551129043 5.44182768232294 8.07206461176593e-08 -90.6415856788723 18.0741759256599 -5.01497750446197 7.24653642451383e-07 OSBPL7 other 5.87210016306595e-13 0.00926542147238339 0.000829404638858949 5.44182768232294 -5.01497750446197 1.96468015211169e-06 140.787477351967 49.2792784261339 2.85693057707809 0.0044498474201828 -305.366382924258 112.396153772461 -2.71687573528943 0.00681102661485247 TMEM98 other 0.0127920324703992 1 1 2.85693057707809 -2.71687573528943 3.28347378398239e-05 104.418137190922 22.8804621296582 4.56363759609441 6.23195750406974e-06 62.5762326217844 41.7236838361613 1.49977726960797 0.134257591499699 YBX2 other 0.189686280500662 1 0.0569974833322219 4.56363759609441 1.49977726960797 0.0162511532076511 38.4656336101773 14.8023982295311 2.59860821292036 0.00962083427804659 -5.61204725477517 35.9131813683947 -0.156267059640504 0.875882023407832 MAP3K14 other 1 1 1 2.59860821292036 -0.156267059640504 0.0230437017444466 7.32810909504355 29.9569391576886 0.244621423319304 0.80684249719222 -184.884967244116 75.1585029790369 -2.45993413806664 0.0142084505524922 ABCC8 other 1 1 1 0.244621423319304 -2.45993413806664 3.3339278023291e-09 869.978563024137 153.277791733008 5.67582918039123 2.29809653304521e-08 -145.420006845453 383.792437545035 -0.378902741741463 0.704915044431519 TMEM132A other 2.65502184589135e-05 1 0.000242357260374948 5.67582918039123 -0.378902741741463 2.7661469290752e-48 2674.74331964295 216.974553336387 12.3274516689344 6.01304168687184e-31 -3655.79575404309 634.807647383156 -5.75890314036582 1.42090377437237e-08 AP2B1 other 4.16332774295109e-44 0.000193399212729823 8.8722430089794e-27 12.3274516689344 -5.75890314036582 0.458097815928404 -3.83330236755492 4.21517034074482 -0.909406277250846 0.363540669052759 -14.0429482075237 12.9985247514401 -1.08034938395359 0.280468000263236 TAC1 other 1 1 1 -0.909406277250846 -1.08034938395359 4.69990506747907e-29 205.375877113743 20.8414344012044 9.85421027939776 3.44762248618698e-21 -358.002841060209 98.1012711021312 -3.64931908667625 0.00028827709633068 ZNF263 other 6.3768311955556e-25 1 4.79116096905405e-17 9.85421027939776 -3.64931908667625 0.425072436632453 92.3805341235803 213.680218569634 0.432330773255342 0.665672031219226 -338.75482417746 464.761215988031 -0.728879287952857 0.466388596631938 CX3CL1 other 1 1 1 0.432330773255342 -0.728879287952857 1.65113985331701e-65 494.793188626986 28.8112184929329 17.1736293884396 9.86138764795478e-53 -966.803958518947 139.956215830065 -6.90790296654522 1.43640442983754e-11 SPATA20 other 2.54952504750679e-61 2.0813500188346e-07 1.51539943986121e-48 17.1736293884396 -6.90790296654522 0.10156857564908 -2.86271661398798 2.66915950386457 -1.07251612720902 0.283984802071771 -26.3706936147219 13.0189054768326 -2.02556917412521 0.0433181832106345 CACNA1G other 1 1 1 -1.07251612720902 -2.02556917412521 3.65696014217e-06 217.526593441508 43.2137231144187 5.03373877010214 6.5563210114319e-07 430.900626496628 196.54400969239 2.19238748192341 0.0287759740006812 TNFRSF12A other 0.023166842500647 1 0.00637995597622438 5.03373877010214 2.19238748192341 0.0361474309623613 10.8359041197051 4.2132593503327 2.57185784655044 0.010382232372688 6.18161133138744 13.3846711676742 0.461842599937523 0.644380542984429 DLX6 other 1 1 1 2.57185784655044 0.461842599937523 2.86673752589786e-06 80.9000338497849 19.1300417505216 4.22895228901313 2.75595392110518e-05 -26.8113652620843 37.377019376 -0.71732218645824 0.473484343533347 MAP3K9 other 0.0183585871158499 1 0.239575074361673 4.22895228901313 -0.71732218645824 1.20478077203433e-12 232.010623300898 32.9432535551464 7.04273556078839 5.68411819440189e-12 -120.282166053659 124.269188587649 -0.967916242317956 0.333513959743328 RALA other 1.13490348725634e-08 1 6.78612437563675e-08 7.04273556078839 -0.967916242317956 2.4800739751305e-06 122.907884490541 38.2909928520944 3.20983801504688 0.00140701957666914 -341.921126650239 117.435165165263 -2.91157360036973 0.00374471711738896 BAIAP2L1 other 0.0159791166217658 1 1 3.20983801504688 -2.91157360036973 2.57053485220025e-07 142.694221116461 33.4781832923783 4.26230479325165 2.38504205033726e-05 -226.392034261574 109.224719668866 -2.0727179245497 0.0386688750776799 KDM7A other 0.00180297314533326 1 0.208452675199476 4.26230479325165 -2.0727179245497 0.809514749257598 -0.177881431497882 19.6391518552756 -0.0090574905071625 0.992776605910724 -44.6256110135311 70.6760952062496 -0.631410250995092 0.528039000197882 ETV1 other 1 1 1 -0.0090574905071625 -0.631410250995092 5.01469603092856e-30 129.768670958095 12.892357014224 10.065550528497 5.67143111638572e-22 -159.275912523203 43.5796377494462 -3.65482415064881 0.00028226017893734 AGK other 6.86211004872264e-26 1 7.9326307024887e-18 10.065550528497 -3.65482415064881 0.00867609946323662 40.0403477468893 14.0893108598275 2.84189540178686 0.00466782912522677 -26.1925778162374 54.3618949920452 -0.48181870444491 0.630145561957991 ALDH3B1 other 1 1 1 2.84189540178686 -0.48181870444491 2.26217929198857e-15 175.888006846225 23.104589192289 7.61268704595389 1.19984885360702e-13 -53.7677783054278 52.2190730484043 -1.02965784658008 0.303629910965867 TTC22 other 2.36329870634046e-11 1 1.49141212503353e-09 7.61268704595389 -1.02965784658008 0.00131125883768214 83.6269574451185 28.706352310742 2.91318648011663 0.00372545427510643 -142.205863576603 96.2939180152491 -1.47678967174317 0.140313868003688 PHTF2 other 1 1 1 2.91318648011663 -1.47678967174317 1.50294410442215e-19 193.982488963378 31.4626823072347 6.16547842517461 1.36897408982069e-09 -291.670133180714 60.8703030376854 -4.7916655351648 2.13558339040272e-06 FARP2 other 1.76355461212895e-15 0.0267097414637669 1.5154543174315e-05 6.16547842517461 -4.7916655351648 0.743367180020778 -6.77035322825626 20.2978395829235 -0.333550435286331 0.738848302142943 -39.1368094988841 50.9249369146458 -0.76851954798649 0.442514545357242 USH1C other 1 1 1 -0.333550435286331 -0.76851954798649 2.63204792001377e-18 746.793802164799 81.0816913356874 9.21038757162808 7.11720336595915e-19 135.402400858889 338.434487363728 0.400084524226892 0.689252185197723 GGCT other 2.99395450901567e-14 1 9.66729733198232e-15 9.21038757162808 0.400084524226892 2.66746355255775e-10 72.5164300613252 12.8939405599512 5.62407044798721 2.9858917009131e-08 -92.885676156871 41.9877056456808 -2.21221128252875 0.0273667319736138 DBF4 other 2.25347320920079e-06 1 0.000313339475093821 5.62407044798721 -2.21221128252875 0.319863521264117 2.82638704727532 2.57500739392029 1.09762288603464 0.272855684437415 -3.30238318440825 6.1988323933474 -0.532742777164354 0.594429593033429 TBXA2R other 1 1 1 1.09762288603464 -0.532742777164354 7.91896893917134e-09 255.958937940349 45.7136436362667 5.59918041049095 3.44074571327774e-08 -117.243303467107 143.107286457821 -0.819268580720819 0.412996638556074 IFRD1 other 6.16412542225097e-05 1 0.000359902001608852 5.59918041049095 -0.819268580720819 2.73464456733907e-47 110.100218471917 8.58074101739811 12.8310851299066 4.55712330803332e-33 -49.1036374385925 15.4577295088789 -3.17663971350951 0.00157538195208055 COX10 other 4.10716267568655e-43 1 6.77006238641429e-29 12.8310851299066 -3.17663971350951 2.21627133993017e-10 123.050390985884 23.003006094942 5.34931784472035 1.31077108485597e-07 -245.347354799793 85.2670500577364 -2.87739935454155 0.00416980304605287 GTF2IRD1 other 1.88294413040467e-06 1 0.00132925295715244 5.34931784472035 -2.87739935454155 2.15388297220685e-48 434.335192425402 29.3342732237958 14.8064071372006 7.06126573406353e-42 -590.104987842288 160.236474145722 -3.68271325856581 0.000253984092161039 PAF1 essential 3.24224003806297e-44 1 1.07069972325605e-37 14.8064071372006 -3.68271325856581 3.65926379212403e-20 201.69142301882 29.7807867136695 6.77253508975444 3.26935131460902e-11 -585.073252239619 112.343991249743 -5.20787312014747 2.70716855467868e-07 VPS41 essential 4.34574167952649e-16 0.00351688266938308 3.81991007598917e-07 6.77253508975444 -5.20787312014747 0.000438566071316605 42.3312943504604 15.8433706791528 2.67186163902364 0.00777310483126199 -37.6449972629864 27.7218491291534 -1.35795404872172 0.175050684492147 ARHGAP44 other 1 1 1 2.67186163902364 -1.35795404872172 1.15580135355425e-59 336.966945968939 31.4050585830097 10.7297028304618 1.81818729454337e-24 -473.69393168763 54.7168172165104 -8.65719089276078 5.65696532802991e-17 ELAC2 essential 1.77473297838255e-55 8.60537565699909e-13 2.59509872550175e-20 10.7297028304618 -8.65719089276078 0.45524981069494 99.0149694041383 92.777966691865 1.06722504205107 0.286345353170183 -123.642910283234 329.814068606775 -0.374886707548697 0.707891368103728 SCIN other 1 1 1 1.06722504205107 -0.374886707548697 0.695072156161338 11.5770632997292 24.7429790989203 0.467892861786979 0.640056867977007 39.3134328831904 46.6168648445917 0.84333069189125 0.399430532910951 MYH13 other 1 1 1 0.467892861786979 0.84333069189125 0.000243948440870409 571.555990535958 203.422615525859 2.80969738324549 0.0051409744958488 -1812.37915552041 807.809224361437 -2.24357323593707 0.0252697224767671 ADIPOR2 other 1 1 1 2.80969738324549 -2.24357323593707 1.06387938565118e-25 11.7102239965598 1.60820120426098 7.28156648902713 1.16049260893692e-12 -19.3870720659091 3.6936378553059 -5.24877446717188 2.19716746102635e-07 CDKL3 other 1.38783065858196e-21 0.00286334863520954 1.40837383020585e-08 7.28156648902713 -5.24877446717188 0.796039052883845 5.95469768265953 9.30334118979265 0.640060120464339 0.522403485877305 0.454397900416905 42.3475291536489 0.0107302104632414 0.991442636087174 PRSS21 other 1 1 1 0.640060120464339 0.0107302104632414 2.27672501904269e-11 120.248141855148 25.3077362936461 4.75143807648014 2.58921812962065e-06 -258.951232471982 75.4120688734144 -3.43381684577111 0.000640582792470249 MARK4 other 2.02765130195942e-07 1 0.0243049905827491 4.75143807648014 -3.43381684577111 1.11313138393418e-09 807.859973497949 286.713605662 2.81765482190028 0.00501380164393942 3581.72964582008 548.225863743196 6.53331023342207 1.48236476887114e-10 PROM1 other 9.08871774982261e-06 2.1120733226876e-06 1 2.81765482190028 6.53331023342207 2.96148572495664e-07 172.930824055362 36.7237543233067 4.70896364606195 3.16539358172013e-06 -184.374904729912 122.037557147879 -1.51080461653699 0.131419935957019 CCDC124 other 0.00206652473887475 1 0.0295141297559585 4.70896364606195 -1.51080461653699 0.45106065667645 1.36212846618687 1.83237572986116 0.743367445873166 0.457581346562634 -4.25360213160307 5.96430199101824 -0.71317685422513 0.476043270379824 CEACAM21 other 1 1 1 0.743367445873166 -0.71317685422513 2.30207684589225e-28 554.882260043419 78.1272324045015 7.10228998219894 3.87393969433607e-12 -857.644298827179 144.771972256626 -5.92410454495227 5.58423387111923e-09 PAFAH1B1 essential 3.10066730373227e-24 7.68669792359562e-05 4.64679066335612e-08 7.10228998219894 -5.92410454495227 0.0331874045197742 1.42912601187962 0.940086751592145 1.52020652291848 0.129096263889421 10.8045392812418 4.39060919158127 2.46082919471832 0.0142012412266926 NOS2 other 1 1 1 1.52020652291848 2.46082919471832 0.000102808508106791 0.968867153180499 3.31346352080813 0.292403144653965 0.770091977327798 -21.7589431898425 5.87455399292006 -3.7039310926525 0.000234381803535464 DNAH9 other 0.557736156479343 1 1 0.292403144653965 -3.7039310926525 6.1814859930551e-42 1786.39366495036 131.245981496823 13.6110351309583 3.35103576170512e-36 -894.013937628276 486.847908078145 -1.83633106519331 0.0668917297628684 KIAA0100 other 9.13067296034169e-38 1 5.02320260679597e-32 13.6110351309583 -1.83633106519331 0.662768337863519 14.4796506256695 15.9582602680973 0.907345185653864 0.364652799645572 18.0273967378778 59.0217631794847 0.305436431694808 0.760158399926558 SLC13A2 other 1 1 1 0.907345185653864 0.305436431694808 0.000378745493202987 -252.170431091926 68.0363086582681 -3.70640965191871 0.000231823815006194 -358.050275063285 120.744374435606 -2.96535782090815 0.0031564643155187 GAS7 other 1 1 1 -3.70640965191871 -2.96535782090815 1.00084646629461e-06 122.55022998644 32.8361791360058 3.7321708314126 0.000209807008544154 -223.047064414634 96.4205836695614 -2.31327229027184 0.0210796842482337 TRAPPC6A other 0.00667764762311764 1 1 3.7321708314126 -2.31327229027184 0.129222094801493 -7.21427755158437 8.28881413980566 -0.870363049515007 0.384485924902275 -40.1977325872624 19.8626203338775 -2.0237879953181 0.0434802854243945 MATK other 1 1 1 -0.870363049515007 -2.0237879953181 0.0086175312753959 7.90925215970007 2.62872384416382 3.00878016428384 0.00274628712777469 2.68277661626013 8.49294369628394 0.31588300973124 0.75221427047106 CEACAM7 other 1 1 1 3.00878016428384 0.31588300973124 0.00256332730862683 -4.75434913753632 3.43582530467869 -1.38375753012301 0.167026384856799 45.2127097257514 15.6929413055468 2.88108575986138 0.00412672192184772 CD79B og 1 1 1 -1.38375753012301 2.88108575986138 0.159311042953086 -3.4901292455038 3.09467817907518 -1.12778422942407 0.25993517677736 -24.4167669099554 14.0739488903208 -1.73489097482425 0.0833572252766971 SCN4A other 1 1 1 -1.12778422942407 -1.73489097482425 2.54971150534686e-15 23.3629699884469 11.3456651796804 2.05919790672907 0.0399506872823427 -163.651711366297 24.8523476868556 -6.5849598367261 1.0738626395075e-10 ST7L other 2.65883915777571e-11 1.53422755306436e-06 1 2.05919790672907 -6.5849598367261 7.30122064889287e-19 97.2527246801883 10.2744664780511 9.46547685837949 9.42189550502121e-20 109.547366520889 36.1768249615479 3.02810892435492 0.00258026036911148 PAX6 other 8.40808569926503e-15 1 1.29211874955861e-15 9.46547685837949 3.02810892435492 2.12712875731785e-17 164.008241365646 18.8569786245675 8.69748248809966 4.14665349884889e-17 41.348353296499 82.8375129022401 0.499150105403283 0.617878061773059 RPUSD1 other 2.36111292062282e-13 1 5.50302385832236e-13 8.69748248809966 0.499150105403283 4.62956419341396e-23 259.350768285759 29.2942374031196 8.85330328681436 1.31241759027259e-17 -325.094685632152 130.276207306803 -2.49542638945996 0.0128870924257427 RHBDF1 other 5.80778828063781e-19 1 1.75417735115834e-13 8.85330328681436 -2.49542638945996 4.57386246281876e-18 176.561799868811 24.2936745391687 7.2678095519943 1.3346708795524e-12 -314.105877807264 108.090539064202 -2.90595162654057 0.00381622300666639 LUC7L other 5.1684645829852e-14 1 1.61828844145728e-08 7.2678095519943 -2.90595162654057 1.49311001503468e-10 18.9066263952371 49.4178702681603 0.382586831294883 0.702181268515883 -531.715869972825 90.8942214874433 -5.84983138940554 8.67296853863969e-09 CACNA2D2 other 1.27795286186818e-06 0.000118819668979364 1 0.382586831294883 -5.84983138940554 6.66138742285082e-16 267.966362474824 35.7402516884444 7.49760703452076 2.68314475463773e-13 -250.418303082671 162.695066510663 -1.53918805562712 0.124344134724622 BAIAP3 other 7.08371938545956e-12 1 3.30912242589472e-09 7.49760703452076 -1.53918805562712 3.55571893572333e-15 237.74418954556 30.6167989457211 7.76515500418721 4.12095630225756e-14 -64.5621324617347 139.372329670196 -0.463234937770727 0.643382613154959 TSR3 other 3.69190297096153e-11 1 5.17880578504707e-10 7.76515500418721 -0.463234937770727 7.93428715335166e-15 359.093088032239 60.2860523303379 5.95648701733837 4.68837989291218e-09 -900.492766879264 265.593636111258 -3.39049075145025 0.000749488632354334 PIGQ other 8.1405786193388e-11 1 5.08079728994893e-05 5.95648701733837 -3.39049075145025 2.29140236554561e-10 173.509726847757 29.3123313601548 5.91934243359486 5.74406141350322e-09 -160.725811079553 132.74067008327 -1.21082567218267 0.226490912043536 CRAMP1 other 1.94585888882134e-06 1 6.207369029838e-05 5.91934243359486 -1.21082567218267 3.69981276005404e-19 159.206562002189 23.1657185859659 6.87250695079401 1.7271553360419e-11 -310.123067129851 77.2251902070249 -4.01582781859746 6.75315233294034e-05 TEAD3 other 4.29548261442274e-15 0.77087233880514 2.03493441692456e-07 6.87250695079401 -4.01582781859746 0.656687655809476 -7.90934894668212 14.0298103904349 -0.563753089070574 0.57315407225878 -81.1454358083208 106.139195111835 -0.764519042402958 0.444888879809617 SELE other 1 1 1 -0.563753089070574 -0.764519042402958 2.12874356144028e-21 238.127628646101 31.7284543350697 7.50517583149007 2.52773366346754e-13 -116.14767633178 51.7785895565298 -2.24316029707559 0.0252889384024171 DNAJC11 essential 2.59110666298511e-17 1 3.11922334071894e-09 7.50517583149007 -2.24316029707559 0.840509929109686 1.97328555520756 17.0335921533484 0.115846706757016 0.907817020372449 72.4484441319361 123.983749349842 0.584338225871117 0.559236359048952 FMO3 other 1 1 1 0.115846706757016 0.584338225871117 7.32187021970276e-06 0.175146558294146 35.4311247538738 0.00494329659334331 0.996057675260746 -551.70622413948 116.84665435364 -4.72162619624286 2.99104359535603e-06 MYLIP other 0.0450514674618311 0.0371517524979173 1 0.00494329659334331 -4.72162619624286 0.00175897386557861 147.799746120064 41.4953667665969 3.56183732394529 0.000400513401115681 100.990490749432 65.6821984839332 1.53756258286841 0.124735946836714 E2F2 other 1 1 1 3.56183732394529 1.53756258286841 1.00815723096051e-42 1023.17531395336 90.2033841785764 11.342981455416 6.84120426360639e-27 -595.032868400711 181.149806182932 -3.28475575513354 0.00108701338757586 PSMB1 essential 1.49348412194489e-38 1 9.90332729199661e-23 11.342981455416 -3.28475575513354 3.45224378116431e-15 216.034227979472 30.3836941725748 7.11020281972397 3.71353891841362e-12 -237.558727469895 100.59165733408 -2.36161460866409 0.0185515572256866 JARID2 other 3.5865360642516e-11 1 4.45773211766371e-08 7.11020281972397 -2.36161460866409 3.35839812338713e-17 107.770544015845 19.5155423259376 5.52229306344254 5.22712113275378e-08 -170.917201610385 40.5075365700244 -4.21939263857541 2.87738760869697e-05 CDK11A other 3.71102992634278e-13 0.337172279987111 0.00054241835994586 5.52229306344254 -4.21939263857541 6.21854130636616e-29 257.60628504751 32.3203476581631 7.97040575714373 9.46193862652323e-15 -328.81700678712 66.3276226198455 -4.95746709740711 9.57636636021832e-07 NADK other 8.42923274077933e-25 0.0121744345537455 1.20516712286026e-10 7.97040575714373 -4.95746709740711 0.0126624585442407 -297.217585572674 122.932943900729 -2.41772120752826 0.0159487005670633 -1185.86730024675 506.013956891219 -2.34354662375781 0.0194638277239537 TFAP2B other 1 1 1 -2.41772120752826 -2.34354662375781 4.71379231790993e-13 38.4303807646014 21.1051527458583 1.82090038519826 0.0691732187538114 -257.420867309729 42.2106677855022 -6.09847891101461 2.03700502326896e-09 DLEC1 other 4.50827097284906e-09 2.83388138837178e-05 1 1.82090038519826 -6.09847891101461 0.787532878366311 -6.78305963520222 32.6253270343477 -0.207907789799657 0.83537920901787 -79.6517706828162 115.313814324498 -0.690739189830916 0.49002570535333 CYTH3 other 1 1 1 -0.207907789799657 -0.690739189830916 0.250920922114075 -6.90435540667526 13.5083940852917 -0.51111593007143 0.609476871434199 -72.2958610911009 43.4549126795078 -1.66369822496948 0.0967476023822398 ADAM22 other 1 1 1 -0.51111593007143 -1.66369822496948 2.38439505261927e-10 163.509976953874 94.9544001216601 1.72198420235795 0.0856418566348062 -1661.69105542423 289.994751121643 -5.73007286855066 1.66537719773913e-08 SYPL1 other 2.0222054441264e-06 0.000226041647049132 1 1.72198420235795 -5.73007286855066 1.67176940729494e-59 1548.94638105845 88.7202410483198 17.458771107428 5.10262986104709e-54 -1373.10095399925 352.7649428905 -3.89239628730756 0.000112224905444257 CYB561 other 2.56633321713846e-55 1 7.84937551524874e-50 17.458771107428 -3.89239628730756 2.10548483187572e-35 463.144685109181 34.2661784305273 13.5160880589056 7.79448099365913e-36 99.1775115831769 137.667855037626 0.720411540922682 0.471599131485708 SPAG9 other 3.01315934289735e-31 1 1.16722352880045e-31 13.5160880589056 0.720411540922682 0.292267112509901 -8.85194777488057 6.16674289973647 -1.43543324552396 0.151739440266428 -20.5148669195208 19.4244179371114 -1.05613805190662 0.291374804267654 AASS other 1 1 1 -1.43543324552396 -1.05613805190662 4.80090651297488e-23 148.595092537261 14.7041929965414 10.1056271889393 4.4195643695907e-22 -49.970625986896 55.1576304788681 -0.905960345886152 0.365366965086926 PLEKHG6 other 6.0203367672705e-19 1 6.18739011742697e-18 10.1056271889393 -0.905960345886152 3.23549972483784e-13 53.5972301657257 11.4241821877943 4.69155947311392 3.43115572524289e-06 -73.9619168814216 22.0144680617281 -3.35969584520661 0.000834783581723282 SS18L2 essential 3.11902173474367e-09 1 0.0319166105562094 4.69155947311392 -3.35969584520661 4.85574226156693e-21 92.5774190437754 16.5172317299482 5.60489920813539 3.31030080924828e-08 -253.709507009266 42.9929146363795 -5.90119346769254 6.33860933079137e-09 MPND other 5.87156354268673e-17 8.71305238610581e-05 0.00034652228871211 5.60489920813539 -5.90119346769254 1.44031020815749e-06 766.013124222536 184.515480515176 4.15148432036049 3.84332965861559e-05 -1000.70387293765 585.427894407647 -1.70935461479879 0.0879651788911521 MGST1 other 0.00947868147988446 1 0.329911417895562 4.15148432036049 -1.70935461479879 0.00317870316751526 14.8884442386331 17.9506162451097 0.829411315764114 0.407234157948204 -120.031766368628 41.3833385169306 -2.90048533226775 0.00387596478310107 CRY1 other 1 1 1 0.829411315764114 -2.90048533226775 2.37298598446291e-12 1315.15051604404 184.160158012363 7.14134115781845 3.02053276258812e-12 -77.4986476158695 615.355431914642 -0.125941274906337 0.89982554708477 NFIX other 2.20972454873186e-08 1 3.63339886011725e-08 7.14134115781845 -0.125941274906337 3.81685958447873e-22 687.827777960901 68.0906287101641 10.1016511521537 4.28151780694523e-22 -949.566375988079 614.495949227268 -1.54527686827255 0.12286404014404 ST3GAL1 other 4.71458495874812e-18 1 5.9954093850654e-18 10.1016511521537 -1.54527686827255 0.00101675563233691 39.2766906698862 11.3064263132338 3.47383776108939 0.00055409891760054 -11.0100920907498 52.7041753830951 -0.208903602242513 0.834601979009452 MMP25 other 1 1 1 3.47383776108939 -0.208903602242513 1.45595609457309e-05 -23.3391407569746 86.1944186500533 -0.270773225488425 0.786668347250045 1792.07984395847 404.825433631784 4.42679657718463 1.15663765618709e-05 IL32 other 0.0872991274306023 0.139062545403374 1 -0.270773225488425 4.42679657718463 8.79288187415936e-17 470.536462955532 59.5073859242873 7.90719430280819 1.57352346918491e-14 -64.1875342276696 127.544104489389 -0.503257555373795 0.614995082526033 MAPK8IP2 other 9.59303412470787e-13 1 1.99365423545728e-10 7.90719430280819 -0.503257555373795 4.22047176534205e-36 39.1472032726152 20.6337223294047 1.89724387328928 0.0583279825998771 -390.795428666801 41.8417342682318 -9.33984777403242 2.49619680683333e-19 RHOBTB2 other 6.06692816267919e-32 3.834158295296e-15 1 1.89724387328928 -9.33984777403242 2.07069007782504e-05 27.5577270555917 31.5800895527978 0.872629794463339 0.383251310604819 -437.061235145657 100.633061000431 -4.34311776667298 1.67706431891292e-05 HEATR5B other 0.122212128393234 0.199838984241664 1 0.872629794463339 -4.34311776667298 1.93250213592963e-05 284.996045933185 80.7269636265464 3.53036994245956 0.0004506953877167 -1103.69765224073 349.910835991029 -3.15422541606864 0.0016994715991977 SEC62 other 0.11452007657519 1 1 3.53036994245956 -3.15422541606864 8.22760286667888e-21 2234.37908537573 228.70385363877 9.76974830037124 8.82020503751192e-21 -2169.24007186073 1798.46913295828 -1.20615918956172 0.228315351764654 RPS20 essential 9.90850213234137e-17 1 1.22203940794728e-16 9.76974830037124 -1.20615918956172 3.25369438160756e-20 2694.33223323972 435.775669339581 6.1828422805775 1.24275630648714e-09 -4684.44963656947 1011.32953202164 -4.6319715663848 4.54397876069123e-06 CSDE1 other 3.86831725029323e-16 0.0559409225228698 1.37809246826359e-05 6.1828422805775 -4.6319715663848 3.88310211680791e-15 387.718477777067 67.1631562277985 5.77278525240886 1.32105194233067e-08 -751.655430382119 197.722978277246 -3.80155830612744 0.000160300556181649 UBE3C other 4.0267768951298e-11 1 0.000140758084455333 5.77278525240886 -3.80155830612744 7.57364025514546e-17 157.750054393268 21.7933900359361 7.23843578870233 1.5721504546319e-12 -97.2642648690099 62.3939726023301 -1.55887276947289 0.119613429806418 REV3L essential 8.28253298302707e-13 1 1.90434584569562e-08 7.23843578870233 -1.55887276947289 0.0127830624024436 82.9594405261058 29.0547734591093 2.85527748625747 0.00446344794494526 38.6759313238259 46.7794346996965 0.826772097014606 0.408727405404112 PAX7 other 1 1 1 2.85527748625747 0.826772097014606 0.0381715966851499 -3.38376087327029 5.35544712934217 -0.631835361557556 0.527759401479681 -21.3614647055483 8.65096137635036 -2.46925905413766 0.0138447641386929 MASP2 other 1 1 1 -0.631835361557556 -2.46925905413766 0.0353345024427233 28.4151094215223 10.9556962346891 2.59363794074094 0.00975194407853625 29.7059157658512 27.1036964708769 1.09600975637291 0.273558576512806 IYD other 1 1 1 2.59363794074094 1.09600975637291 1.03771100325294e-22 44.9847728792631 9.78902783854055 4.59542802627987 5.3754025608573e-06 -87.3398226503425 15.312325222245 -5.70389025720663 1.9257478183785e-08 FAM76A other 1.2947520187587e-18 0.000260823284521184 0.0493945741317178 4.59542802627987 -5.70389025720663 0.0740530325686287 12.033677742322 7.92234749116266 1.51895353690879 0.129364901455861 96.6835873174386 53.6440367820802 1.80231751965646 0.0720581727779503 TRAF3IP3 other 1 1 1 1.51895353690879 1.80231751965646 6.00021577535619e-26 42.283267833968 14.9420492293184 2.8298171947528 0.0048294980203027 -275.820820315956 31.4180140068633 -8.77906605604359 2.13751742393732e-17 POMT2 other 7.86208273044921e-22 3.25992782324681e-13 1 2.8298171947528 -8.77906605604359 9.2749424538491e-42 316.566618649107 29.2962338147121 10.8057104080775 1.0034473639078e-24 -257.132369754048 64.1483992387446 -4.00839885025134 6.99315445799167e-05 VTA1 other 1.36870325791451e-37 0.797429402844791 1.4345283514426e-20 10.8057104080775 -4.00839885025134 0.255843918212753 21.1166518300781 13.3829887239176 1.57787264606591 0.115192636281169 40.7993316564999 49.7466537792512 0.8201422318282 0.412504412889046 MLXIPL other 1 1 1 1.57787264606591 0.8201422318282 1.72652793242577e-07 348.7553645239 79.9467830105445 4.36234394169307 1.54746603340589e-05 -787.904668441737 301.846593711042 -2.61028179498358 0.00930319504436287 BAZ1B other 0.00122825197112769 1 0.137198338521766 4.36234394169307 -2.61028179498358 4.23270172797669e-19 324.738804669804 39.2319059374967 8.27741596819612 1.00289915883814e-15 -313.10429226927 133.89155253693 -2.33849175946263 0.0197277417763627 RANBP9 other 4.90824092376177e-15 1 1.29835325103186e-11 8.27741596819612 -2.33849175946263 1.51714000903149e-06 52.1998398338424 9.98540524050376 5.22761355964847 2.45050934139139e-07 45.9853074457562 33.6364783049162 1.36712610127901 0.17214938582409 ETV7 other 0.00995850701928272 1 0.00244879398485241 5.22761355964847 1.36712610127901 2.71727211324897e-24 66.5727991898319 6.07738411039596 10.9541865349522 2.29214655297847e-25 5.66509167831418 37.0634680610842 0.152848396943793 0.878574610911149 SPRTN essential 3.47457585121146e-20 1 3.28900108886881e-21 10.9541865349522 0.152848396943793 1.01202355710406e-22 208.985190606794 19.8010392992993 10.5542536150711 8.32519183097337e-24 102.298809098507 145.0190313432 0.70541644190415 0.480854727222355 METTL13 other 1.26320780397728e-18 1 1.18350927069117e-19 10.5542536150711 0.70541644190415 9.54524721663478e-31 97.9958621675746 9.05619307537908 10.8208671515622 7.55095496731649e-25 -105.211257797529 32.6571134118497 -3.22169496338132 0.00135056063494301 DYRK4 other 1.31447599420278e-26 1 1.08046614627332e-20 10.8208671515622 -3.22169496338132 9.49058253279432e-14 575.612667617854 115.591263756628 4.97972466872391 8.67717204052571e-07 -651.896982934465 210.386683303234 -3.09856580606329 0.00204977425780843 UQCRC1 essential 9.34158038702945e-10 1 0.00838214819114784 4.97972466872391 -3.09856580606329 3.34800927470182e-21 98.1132942599376 11.7738096259805 8.33318164440485 6.35850456463519e-16 -158.510910413043 44.8996161009182 -3.53033999348163 0.0004499428005917 STARD3NL other 4.06147005114078e-17 1 8.26414838265636e-12 8.33318164440485 -3.53033999348163 5.56372051788354e-17 1503.7603354855 237.687849378924 6.32661845952499 5.23723196611228e-10 -4177.94188108069 884.357279276465 -4.72426922804194 2.94355093554207e-06 CD9 other 6.10673964042897e-13 0.0365853945778523 5.89345713146615e-06 6.32661845952499 -4.72426922804194 1.06866161259544e-49 1459.82333613209 87.2528099567491 16.7309607204137 1.16934484279394e-50 809.036427397878 331.35869315508 2.44157296642657 0.0149531770818028 NCAPD2 essential 1.61474769663171e-45 1 1.79307338194023e-46 16.7309607204137 2.44157296642657 0.00306199156856595 -17.0440664564348 5.34182930623174 -3.19067972399479 0.00150541324158338 -38.8910494625346 20.2161334314032 -1.92376299822608 0.0549319468905777 IFFO1 other 1 1 1 -3.19067972399479 -1.92376299822608 0.000606595672759981 0.202313947594347 6.58214879846068 0.0307367629916937 0.975490683684312 -72.2614553762052 19.8288329931068 -3.64426163664427 0.000293720548197877 GIPR other 1 1 1 0.0307367629916937 -3.64426163664427 1.0598369934002e-35 6.69424406505475 4.64018602554954 1.4426671750217 0.149704956504689 -94.8275494888171 8.48642249584522 -11.1740311698178 3.54817845231421e-26 PHF7 other 1.51970026483655e-31 5.53409393207448e-22 1 1.4426671750217 -11.1740311698178 0.0738562082013427 52.7064093604339 90.1662038352564 0.584547281781258 0.55910090200512 -270.418796423055 164.904703470776 -1.63984889897927 0.101629944970584 SEMA3G other 1 1 1 0.584547281781258 -1.63984889897927 2.57649993739894e-32 -0.205950849038299 67.7883889762953 -0.00303814343648611 0.997577057007916 -1397.15641267406 124.037019610572 -11.2640276028929 1.54229406398457e-26 NISCH other 3.59988571253379e-28 2.40628719862873e-22 1 -0.00303814343648611 -11.2640276028929 0.156328541956783 -53.3088216318668 65.3023180169597 -0.816338887358057 0.414676581978844 -226.664133784724 117.754778769036 -1.92488267698505 0.0547840285509114 STAB1 other 1 1 1 -0.816338887358057 -1.92488267698505 1.51273113237694e-09 9.02304386136004 18.3476359399442 0.491782368632908 0.623073044362637 -369.628118533069 60.4513691104296 -6.11447058970411 1.85909473401708e-09 FUZ other 1.22697622147094e-05 2.58897532659219e-05 1 0.491782368632908 -6.11447058970411 7.92089542338824e-07 24.2683839373726 4.80274246197737 5.05302629268631 5.94764446809208e-07 -3.39150835800761 22.72214340268 -0.149260054296092 0.881403750678468 ZNF200 other 0.00534264396307537 1 0.00580014288528339 5.05302629268631 -0.149260054296092 0.087878034593654 7.3939158619107 42.4379937674857 0.174228685324319 0.861751897823719 343.478549014908 157.29879753801 2.18360568797043 0.0294265361916623 CD4 other 1 1 1 0.174228685324319 2.18360568797043 4.76736942340958e-19 53.6268478798105 8.16718534140322 6.56613577849781 1.22202178541701e-10 -135.544670075866 28.639229769801 -4.73283224323277 2.83677760715147e-06 LRRC23 other 5.51918358148127e-15 0.0352895134329643 1.40434743580122e-06 6.56613577849781 -4.73283224323277 3.98107210010552e-06 -5.74990576247944 13.4561384103622 -0.427307269524784 0.669326186059283 -263.944031651299 53.3212012331241 -4.95007662144214 9.93603629322456e-07 HFE other 0.0251086217353655 0.0126205344259158 1 -0.427307269524784 -4.95007662144214 2.42844749102464e-18 161.389380549256 31.2797888476555 5.15954187975128 3.48931167982398e-07 -409.895656449224 70.0410988855266 -5.85221624119785 8.44485243746808e-09 SCMH1 other 2.76503031328066e-14 0.000115753592360375 0.00345686108120162 5.15954187975128 -5.85221624119785 0.0228333606580554 54.1473750691595 32.1762100984884 1.68283880865457 0.0929854057723577 -114.22153885338 92.1197467682394 -1.23992458577579 0.215542820468323 FYN other 1 1 1 1.68283880865457 -1.23992458577579 6.01522539331864e-06 122.885808779412 32.5655684120694 3.77348883411069 0.000179110549318001 -70.2675070950525 71.4936518570444 -0.982849599507888 0.32612906597393 HIVEP2 other 0.0372402604100357 1 1 3.77348883411069 -0.982849599507888 0.366314781442334 5.92233372383074 8.40269211333616 0.704813843462291 0.481228842721973 -72.3617966403006 61.1615725930484 -1.18312518093306 0.237278230627186 FMO1 other 1 1 1 0.704813843462291 -1.18312518093306 1.04940822363845e-20 236.640721364864 45.0206420441736 5.2562715816597 2.11365217204421e-07 -319.447322622432 71.2803538109063 -4.48156196684807 9.03581133820095e-06 ELOA other 1.26023433576742e-16 0.109405603682937 0.00212062722421196 5.2562715816597 -4.48156196684807 1.18295990051052e-15 254.641216996134 57.8869710962031 4.39893834785279 1.30878650906506e-05 -360.254236364579 91.6513757562696 -3.93070189500058 9.56073347640296e-05 LYPLA2 other 1.24790439904854e-11 1 0.116809195934056 4.39893834785279 -3.93070189500058 2.23676566854877e-13 -19.9542873593667 14.7412014892002 -1.3536405003341 0.176415306602134 -172.746262579535 23.6163654569484 -7.31468450953826 9.33644601986983e-13 CLCN6 other 2.17078108132659e-09 1.37227083600047e-08 1 -1.3536405003341 -7.31468450953826 0.202407689154801 -127.139152979129 87.8622894274945 -1.44702754512271 0.148501163801939 267.265115502673 339.732118452736 0.786693694784867 0.431825166728114 MRC2 other 1 1 1 -1.44702754512271 0.786693694784867 1.06467310981187e-40 2698.59029776604 187.274122775813 14.4098408139204 9.00766884225865e-40 -473.339501010883 730.785394168234 -0.647713411882881 0.517460088151198 NME1-NME2 other 1.56379186369168e-36 1 1.36087860868844e-35 14.4098408139204 -0.647713411882881 2.69130919001635e-09 61.750290566067 45.9549341787306 1.34371404658974 0.17960520500139 -933.587916555249 165.208008044019 -5.65098464419773 2.58496696051332e-08 TSPAN9 other 2.15331648293208e-05 0.000348763742312457 1 1.34371404658974 -5.65098464419773 5.59195068369855e-16 48.5687437423797 30.1291170568392 1.61202014817606 0.107535403217685 -434.85124651989 61.2852960949384 -7.09552330213518 4.01943868333479e-12 BTBD7 other 5.95878264854918e-12 5.86395909511712e-08 1 1.61202014817606 -7.09552330213518 3.89770302258968e-17 24.7312048732463 8.3806691805745 2.95098211615017 0.00330442357991398 -135.581717841244 20.0787060667012 -6.7525127062891 3.7448224977397e-11 APBA3 other 4.30072551512545e-13 5.39104646774608e-07 1 2.95098211615017 -6.7525127062891 2.3436561685793e-54 88.2348682977617 5.92989447152079 14.8796692287735 5.63294476562958e-42 -158.418536878892 24.6361093358023 -6.43033908964963 2.88710265856031e-10 MKS1 other 3.57009144159685e-50 4.09246801850923e-06 8.54405062050694e-38 14.8796692287735 -6.43033908964963 2.32993649940139e-13 82.8209788254281 15.3172696046158 5.40703277824856 9.58739629885852e-08 -70.9699340214269 29.3035340818742 -2.42188992710356 0.0157640866696598 ABHD5 other 2.26027139806929e-09 1 0.000980503019484261 5.40703277824856 -2.42188992710356 3.65768999152345e-09 132.890962956825 33.8306615884529 3.92812190826867 9.67160708805723e-05 -447.671439945534 119.747902315638 -3.73844911926338 0.000204915984138386 AKAP8L other 2.90676623626369e-05 1 0.800325486536736 3.92812190826867 -3.73844911926338 1.3079349110839e-33 152.633131139173 12.073681409829 12.6418054243933 4.35080977697404e-32 -62.9699263784774 46.998545810895 -1.33982712213789 0.180893585168873 MBTD1 other 1.84641171397714e-29 1 6.44180895578777e-28 12.6418054243933 -1.33982712213789 2.04266303136411e-74 320.371227634337 15.0383383580268 21.3036320906649 1.5240872849091e-72 -46.4146795110522 54.637705302435 -0.849499063954717 0.396001459936784 UTP18 essential 3.16817036164574e-70 1 2.36812682329176e-68 21.3036320906649 -0.849499063954717 3.11432996588832e-10 137.2712475729 26.0741218213983 5.26465468379629 2.03188945590628e-07 -250.485377684869 91.6545951240108 -2.73292765459229 0.00648353308848168 RNF216 other 2.62195439828137e-06 1 0.00203961063583873 5.26465468379629 -2.73292765459229 7.84344235601353e-61 284.892411382881 38.3287946124671 7.43285600977951 4.20012164056894e-13 -846.501904935046 69.437781669538 -12.1907970643942 2.31330221254549e-30 TTC19 other 1.20671360647268e-56 3.61985530219118e-26 5.14892911917347e-09 7.43285600977951 -12.1907970643942 3.13193376178675e-13 6.02832522024596 0.774247493625056 7.78604421697397 3.5326528435759e-14 8.61284729975125 4.66788982258615 1.84512651907013 0.0655644618529844 DPF1 other 3.02231608012421e-09 1 4.44655013420899e-10 7.78604421697397 1.84512651907013 0.0017393452952719 386.501459859942 149.114803343139 2.59197243462498 0.00981210845212972 -510.010466767087 385.265438924836 -1.32378982187029 0.186156750761439 SYT7 other 1 1 1 2.59197243462498 -1.32378982187029 8.477962663012e-23 65.886011502666 16.8300218247965 3.91479061575505 0.000101885263254015 -213.991150992048 31.4550511929797 -6.80307749872005 2.68956696840941e-11 LARS2 essential 1.05949099399661e-18 3.88077617871794e-07 0.841572274478162 3.91479061575505 -6.80307749872005 8.09629525070905e-15 282.531148241365 57.8658292564785 4.88252137525073 1.38078639928501e-06 -649.371550278144 146.122961900619 -4.44400757986136 1.07156451508608e-05 PIK3C2A other 8.30437003865227e-11 0.129123524067873 0.0131713214627797 4.88252137525073 -4.44400757986136 0.000803717730067546 153.745425830753 43.7285560924789 3.51590446996708 0.000474552576471052 343.517799842469 138.837131609873 2.47425019416088 0.0136533267963825 PLAUR other 1 1 1 3.51590446996708 2.47425019416088 0.000141406563481178 280.742965874265 73.8726787523228 3.80036260517271 0.000160802892064439 790.976959108807 282.961195662796 2.79535487986633 0.00536738529509198 ANLN essential 0.753131357100755 1 1 3.80036260517271 2.79535487986633 3.09645409207971e-27 363.408164290493 35.4385670255451 10.2545953403967 1.15381875916473e-22 -354.07830191869 128.978285438997 -2.74525514673676 0.00624781963944103 WIZ other 4.12076110573968e-23 1 1.62385947848759e-18 10.2545953403967 -2.74525514673676 0.0407970155913023 -1383.77550883483 981.589692973496 -1.40972905353459 0.15920402071557 -6314.32903605459 2620.74928328802 -2.40936020714373 0.0163191584899297 DCN other 1 1 1 -1.40972905353459 -2.40936020714373 0.000505495354533128 17.1747581373822 10.8205032562555 1.58724208390706 0.113035677759896 -93.0852113705978 32.5969464591618 -2.85564206105063 0.00445810151572242 QPCTL other 1 1 1 1.58724208390706 -2.85564206105063 3.42387400925702e-21 216.733725649904 27.9716961201866 7.74832261578488 4.56750099355095e-14 -281.310840133603 81.6448990744166 -3.44554091342801 0.000613752238775688 PPP5C other 4.15315917322876e-17 1 5.73495424750257e-10 7.74832261578488 -3.44554091342801 0.0432239328760126 -47.5212257579349 22.3373790574496 -2.12743069075896 0.0338334702602884 -128.771009290856 76.6824657857 -1.6792758027725 0.093672508557332 CEP68 other 1 1 1 -2.12743069075896 -1.6792758027725 1.0980507604286e-05 42.1858878207996 28.6400453156466 1.47296861285875 0.141341045721113 -381.362462734301 89.9558617214033 -4.23943982567134 2.63502947453313e-05 MAP4K3 other 0.0665418760819729 0.309457861489171 1 1.47296861285875 -4.23943982567134 2.5501088463529e-07 3.44088111557656 0.638774190901451 5.38669402206235 1.06912985990374e-07 -1.1235277781018 2.94722965693292 -0.38121487256986 0.703192377938756 ZBTB32 other 0.00178941137748583 1 0.00108944332724191 5.38669402206235 -0.38121487256986 0.044473876863586 -89.3535620259353 37.3019239944657 -2.39541429657066 0.0169386454593909 -204.118517827158 172.140007215677 -1.185770357099 0.236230669318571 TYROBP other 1 1 1 -2.39541429657066 -1.185770357099 8.36258163542782e-09 150.013831022328 26.9600047295471 5.56431026356309 4.13518275954602e-08 -170.208190585722 144.122670053381 -1.18099526273473 0.238120675306501 TMEM159 other 6.50023470521804e-05 1 0.000431010099027481 5.56431026356309 -1.18099526273473 2.58182103562719e-24 211.241684568587 21.5474904622593 9.80353999638979 5.60379385962337e-21 -25.66367525382 47.5133272074558 -0.540136352517801 0.589327765138232 BRCA1 ts 3.30344001508499e-20 1 7.77806587715723e-17 9.80353999638979 -0.540136352517801 6.9427108416099e-20 162.642467855648 33.8143118465713 4.80987070189746 1.95540988870101e-06 -651.431155021313 101.202321027407 -6.4369191181386 2.66838521402486e-10 ERCC1 ts 8.20211858827793e-16 3.78483758757286e-06 0.0184844896778907 4.80987070189746 -6.4369191181386 0.114314832996625 -2977.75446615425 4231.25175327321 -0.703752610288603 0.481890750671951 -16295.9613976487 7906.24825064396 -2.06114972374178 0.0397678432744653 LTF other 1 1 1 -0.703752610288603 -2.06114972374178 9.78055834732638e-25 139.252826989069 38.6411244510764 3.60374675859593 0.000342561915271535 -454.348238225185 77.8740691812096 -5.83439703359967 9.29344183611443e-09 EXTL3 other 1.25934469280175e-20 0.000127199338410898 1 3.60374675859593 -5.83439703359967 0.00421745230431881 -1158.6171496882 479.551698326564 -2.41604221970496 0.0160317958784891 -5138.05806977859 1761.923999317 -2.91616328046518 0.00369575750240506 ELOVL5 other 1 1 1 -2.41604221970496 -2.91616328046518 0.00412654153990254 -62.5783093142366 28.5890781490795 -2.18888867237755 0.029033187939551 -248.073138001541 81.8393095070133 -3.03122227565083 0.00255269415363168 ALOX5 other 1 1 1 -2.18888867237755 -3.03122227565083 1.86104560572542e-11 142.628917592677 53.3350138507858 2.67420794136676 0.0077187936129391 -939.482358767203 164.534604219522 -5.70993781656865 1.87232249225735e-08 CALCOCO1 other 1.6639608760791e-07 0.000253737144150716 1 2.67420794136676 -5.70993781656865 4.90661625833501e-24 178.138515138859 47.3442891966338 3.76261885354327 0.000186334491814551 -749.679175542816 96.1379303538735 -7.79795417670556 3.20931920805713e-14 UBR7 other 6.2480851433638e-20 4.78477400729237e-10 1 3.76261885354327 -7.79795417670556 1.58449144110109e-07 116.178895056818 30.9456635848117 3.75428675938426 0.000192550927720587 -222.590778932649 74.2438033830427 -2.99810581880143 0.00284078533427678 MAP4K5 other 0.00113037619408152 1 1 3.75428675938426 -2.99810581880143 0.187952180987662 8.60969711067167 15.2239030784801 0.565538092714343 0.571940141955481 -75.8414162526793 47.8741774276585 -1.58418212756306 0.113731279189065 EHD3 other 1 1 1 0.565538092714343 -1.58418212756306 1.7262870628531e-81 647.523466478447 28.6345230827764 22.6133840122496 1.79070698732502e-80 66.8001825313217 166.119754027874 0.402120644364263 0.687752032270384 PSMC4 essential 2.68610266979942e-77 1 2.78938427415618e-76 22.6133840122496 0.402120644364263 8.00630679613085e-36 58.6386857002094 63.6928238036445 0.920648233166483 0.357642186959992 -1402.67033198906 122.455391003268 -11.4545412863989 2.30453157166411e-27 MAN2B2 other 1.1490651513807e-31 3.59829559599634e-23 1 0.920648233166483 -11.4545412863989 2.16657704702795e-29 979.877584789117 91.4163427378673 10.7188447430989 1.98495216041147e-24 -269.195596177973 214.148067827144 -1.2570535840429 0.209279681807693 SLC25A39 other 2.94806138789093e-25 1 2.83272522812321e-20 10.7188447430989 -1.2570535840429 4.13673930383184e-14 630.314570199953 97.7244023155044 6.4499199305919 2.51319594302823e-10 -1932.39978878101 603.76000299749 -3.20060914798466 0.00145306477973703 MVP other 4.12805215129379e-10 1 2.85951434397752e-06 6.4499199305919 -3.20060914798466 1.73304651380322e-18 233.241456729912 37.5557260014039 6.21054314650162 1.04816419930237e-09 -528.769186767664 115.40112787679 -4.5820105617357 5.71398307085465e-06 NUB1 other 1.9798323373688e-14 0.0699848646518278 1.16597785530396e-05 6.21054314650162 -4.5820105617357 1.87590608099484e-19 216.720868148415 45.2959090341973 4.78455720989717 2.22383988954656e-06 -453.111714603069 99.3473559541411 -4.56088348050477 6.33107773351912e-06 PGM3 other 2.19640260608737e-15 0.0773341145149361 0.020966362478645 4.78455720989717 -4.56088348050477 1.58062571478303e-10 14.6996758114994 8.21133683825796 1.79016840997329 0.073996460932779 -83.726552971086 18.0098958410102 -4.64891933358288 4.21536984035325e-06 RWDD2A other 1.35175111128245e-06 0.0519965869807574 1 1.79016840997329 -4.64891933358288 4.94955635575011e-06 -108.387843754066 61.2788235610681 -1.76876508809035 0.0774996491843328 -760.99327551846 153.112349726849 -4.97016260854244 9.0054278711757e-07 CLK1 other 0.0309099794416594 0.0114657107655809 1 -1.76876508809035 -4.97016260854244 8.52538858013104e-11 53.805083980283 10.357360932696 5.1948642448514 2.90284403354915e-07 -66.1248085578725 23.8213076756095 -2.77586812018626 0.00569535814703454 POLR3B essential 7.3778712772454e-07 1 0.00288949095099482 5.1948642448514 -2.77586812018626 1.19710025426103e-22 79.9804598396501 19.1907897541362 4.16764817208275 3.57884221461438e-05 -280.845592229072 40.182404557281 -6.98926794758437 8.10322329110355e-12 ANGEL1 other 1.49158691680924e-18 1.17804660206063e-07 0.308102526256152 4.16764817208275 -6.98926794758437 4.70181245196479e-32 242.260100676692 37.8921965388033 6.39340346576654 3.48028394713366e-10 -714.622206182902 88.0766397921585 -8.11364066419034 3.25592038833088e-15 RNF14 other 6.5576178267553e-28 4.89820663220498e-11 3.94490185407601e-06 6.39340346576654 -8.11364066419034 1.10259506802159e-32 225.528273365619 17.8734240423558 12.6180788208891 4.14092690920771e-32 -76.9804768453334 90.3393669279226 -0.852125484859247 0.3945286012656 DDX11 essential 1.54627932339348e-28 1 6.13188456715478e-28 12.6180788208891 -0.852125484859247 0.00227993572307508 -35.2966315522489 187.579413837001 -0.188169004424549 0.850814858639808 -2028.12832847956 600.677912527382 -3.37639904211911 0.000787281478218361 HEBP1 other 1 1 1 -0.188169004424549 -3.37639904211911 0.969618648413818 2.44275293594912 12.154074344363 0.200982227583794 0.840791361620361 -1.68036228104963 31.3601026862634 -0.0535828054474347 0.957288214279583 CD6 other 1 1 1 0.200982227583794 -0.0535828054474347 1.0490966510045e-37 639.422759681127 45.2704353254061 14.1245109547749 9.5531636640443e-39 750.207387678776 117.349163548677 6.39295044798158 3.53746499456898e-10 TACC3 essential 1.52003613764042e-33 5.00374423481782e-06 1.44071261217452e-34 14.1245109547749 6.39295044798158 4.86944890170378e-23 189.707721704838 35.5109460741211 5.34223226012808 1.36036300923261e-07 -405.583760079009 80.7546725650101 -5.02241848299863 6.96370555118584e-07 UFL1 essential 6.10482808806603e-19 0.00890727577052181 0.00137791169205171 5.34223226012808 -5.02241848299863 2.44461732879774e-10 94.0294787161394 19.9163448189112 4.72122166848887 3.0203008899324e-06 -140.215994899022 49.5166233621496 -2.83169540607655 0.00480997423329592 POLA2 essential 2.07205764788896e-06 1 0.0282126306128585 4.72122166848887 -2.83169540607655 3.97780682065732e-31 137.591459301788 11.0035779229901 12.5042472789068 1.75899870919145e-31 -52.6450502204421 75.788034780193 -0.694635378435762 0.487600156531908 ZC3H3 other 5.50170461365115e-27 1 2.59962419231404e-27 12.5042472789068 -0.694635378435762 8.73619071002801e-16 555.359816061064 133.856124193975 4.1489309466056 3.89829544938498e-05 -1790.61046665365 328.723166531029 -5.44716846564154 7.88935903032155e-08 CAPN1 other 9.25686767634568e-12 0.00104802245358791 0.334512732511725 4.1489309466056 -5.44716846564154 0.082290141424146 9.01037923580192 4.02485730950744 2.23868290051371 0.0255779361771084 4.35574345912926 13.8056182523341 0.31550513562787 0.752498486425029 ACPP other 1 1 1 2.23868290051371 0.31550513562787 1.33175252661961e-19 668.949737284516 69.9024221358352 9.56976477845939 3.72004308642947e-20 -3.14872969988932 243.391133958774 -0.0129369120751237 0.989682868454451 MDH1 other 1.56440969302005e-15 1 5.1243593515566e-16 9.56976477845939 -0.0129369120751237 4.59704369599226e-27 321.832928906142 56.9810193436267 5.64807250929145 2.6110865713415e-08 -733.204506572749 118.169273003374 -6.20469677046935 1.08261926501388e-09 SLC30A9 other 6.10395461953852e-23 1.51555870909294e-05 0.00027486908336512 5.64807250929145 -6.20469677046935 0.000387572382628544 38.0363469300235 10.0355189071689 3.79017241478686 0.000168642406401396 123.882965946248 122.386358417203 1.01222854857682 0.311911608684985 MTMR11 other 1 1 1 3.79017241478686 1.01222854857682 8.54158806012755e-28 141.347630808087 24.8516850146155 5.68764776814768 2.10675738136814e-08 -354.759313783368 48.7297284415001 -7.28014140709313 1.17683038311909e-12 COX15 essential 1.14337697772867e-23 1.72770468545714e-08 0.000222536782193917 5.68764776814768 -7.28014140709313 1.10341149649214e-12 58.3479481400619 66.3500858125475 0.879395217436593 0.379574594044099 -888.754070455459 135.407974880148 -6.56352826517132 1.22530857006395e-10 CCDC88C other 1.04095840579068e-08 1.74925051462329e-06 1 0.879395217436593 -6.56352826517132 2.00159308095031e-12 35.684132267236 7.00487844376025 5.09418294032247 4.88960655573234e-07 -94.7788144062442 22.0411255884651 -4.30008957690642 2.03530719928993e-05 YAF2 other 1.86848714106711e-08 0.241204256187849 0.0047991488344513 5.09418294032247 -4.30008957690642 4.15449701296725e-09 273.149479883018 64.2915185453032 4.24860830889447 2.54680041856087e-05 -1025.73596922105 259.301915817075 -3.95575931627384 8.6813129006983e-05 ZMYND11 other 3.28911528516617e-05 0.983161840080446 0.222076513712514 4.24860830889447 -3.95575931627384 0.277677293711908 -3.6892294971756 3.67271483170753 -1.00449658256217 0.315599432866613 2.73164926705258 7.92188924502201 0.344822956060526 0.730364783880541 DPEP1 other 1 1 1 -1.00449658256217 0.344822956060526 4.51509149385116e-14 153.648753061751 22.1937031897217 6.92307866552475 1.25176068346421e-11 8.41036211445142 41.9709610127796 0.200385264275712 0.841254310810126 BID other 4.49793414617453e-10 1 1.4812084167432e-07 6.92307866552475 0.200385264275712 6.4895625768043e-15 363.421861680691 145.455304726824 2.49851225682848 0.01276604690077 -2242.9914058411 342.343385234933 -6.55187598937203 1.3211927296928e-10 MATR3 other 6.68100467282002e-11 1.88441719036084e-06 1 2.49851225682848 -6.55187598937203 0.0281053943274927 14.9056485899871 7.07658653751177 2.1063331185134 0.0356423231156493 -34.1755382218487 27.9682595428132 -1.2219401128459 0.222270405938306 NPC1L1 other 1 1 1 2.1063331185134 -1.2219401128459 4.3898973580525e-61 260.113005800165 15.7370105389574 16.5287431914878 9.85626564162682e-50 -409.072994797359 69.1614629474437 -5.91475335199628 5.98962780791431e-09 XYLT2 other 6.75473506483537e-57 8.23933201256693e-05 1.51007845895364e-45 16.5287431914878 -5.91475335199628 8.79220090196756e-26 352.593168460732 43.4602796519354 8.11299815106069 3.41376873026948e-15 -1069.53423910105 172.036571406947 -6.21690045525901 1.02304588837433e-09 NUDCD3 essential 1.1488768918601e-21 1.43277576666825e-05 4.37918252718969e-11 8.11299815106069 -6.21690045525901 3.12010944153158e-24 54.0618608427474 58.9945617787878 0.916387192525703 0.359877503777845 -983.086990696866 108.297026555423 -9.07769143775849 2.13389296280461e-18 CHDH other 3.98562780061244e-20 3.26848385112782e-14 1 0.916387192525703 -9.07769143775849 1.78609319631084e-05 -58.4948150225234 35.7126020007874 -1.6379320392626 0.10203163279492 -384.030747541589 81.7961638723991 -4.69497259236596 3.40311842783153e-06 IL20RA other 0.106201101452643 0.042157831083977 1 -1.6379320392626 -4.69497259236596 7.38815382898841e-54 85.4025160490114 26.0527563621317 3.27806067281026 0.0011131178242257 -638.958008319607 47.3262560218426 -13.5011315499943 5.89530740325648e-36 GLT8D1 other 1.12484642046348e-49 9.23853623164323e-32 1 3.27806067281026 -13.5011315499943 1.312845016581e-13 672.56489988585 86.6820565206907 7.75898642558522 4.25787610651759e-14 -46.6787265213154 294.534181922167 -0.158483223294098 0.874134853638507 ATP2C1 other 1.28698196975435e-09 1 5.35002132783935e-10 7.75898642558522 -0.158483223294098 0.221383313001308 -72.7951194913383 55.4067714253574 -1.31383073979335 0.18945491790967 -198.538945833582 134.110474595562 -1.48041341612068 0.13933973242153 IGF1 other 1 1 1 -1.31383073979335 -1.48041341612068 2.90825039124666e-32 536.352189249885 67.1091289580687 7.99223887386484 8.05213133145681e-15 -802.310374817247 146.815524754786 -5.46475160687046 7.08382035778068e-08 RALBP1 other 4.06166249641508e-28 0.000942148107584831 1.02656622344743e-10 7.99223887386484 -5.46475160687046 1.11480420561001e-10 60.4358932895875 17.4451027102021 3.46434723220312 0.000573899146018331 -211.57282584055 48.4044450495193 -4.37093795051476 1.48531175233719e-05 RUFY3 other 9.59400499347973e-07 0.177494754404294 1 3.46434723220312 -4.37093795051476 0.396139676505714 -37.6808138069016 27.8382412475241 -1.35356301685376 0.176460511616341 -39.1107614548748 91.2937715533597 -0.428405583309867 0.668532236179468 CNTN1 other 1 1 1 -1.35356301685376 -0.428405583309867 0.0290714778434475 29.4716871936874 11.9186405861827 2.47273898231767 0.0137133324661508 44.4766299296429 27.0829317705743 1.64223837752923 0.101119570620746 SLC11A1 other 1 1 1 2.47273898231767 1.64223837752923 6.46096338331257e-15 773.145180731275 93.0521965582855 8.30872574025693 7.71759687371623e-16 412.062187751598 365.243839893304 1.12818381241411 0.259738693969456 WWTR1 other 6.65220789945862e-11 1 1.00158972227089e-11 8.30872574025693 1.12818381241411 0.00850608968756764 -114.703618104415 76.030411289273 -1.50865444707384 0.131974120323464 -552.669074120451 182.406516674688 -3.02987570946331 0.00256412926482122 AGPS other 1 1 1 -1.50865444707384 -3.02987570946331 0.853602233288306 15.702834142798 56.6119436108465 0.277376700767246 0.781597417877261 -274.444491799725 556.333030365696 -0.493309720652975 0.621995061244447 ATP1A2 other 1 1 1 0.277376700767246 -0.493309720652975 5.70634080533879e-14 91.3257356904818 12.2284982230618 7.4682707577493 3.23020348716766e-13 -45.0544551902272 38.2507545807575 -1.17787101676923 0.239360223284352 TTC27 essential 5.66525515154035e-10 1 3.97541143165724e-09 7.4682707577493 -1.17787101676923 4.35354726161015e-06 7.40993522976366 2.51988680300158 2.94058257733532 0.00341531174598536 -36.2342668161929 10.3572344329735 -3.49845000136683 0.000506276683780094 ZNF582 other 0.0273489838974349 1 1 2.94058257733532 -3.49845000136683 0.000216843912811682 -31.3107052177318 24.2839558904483 -1.28935768780767 0.19783091222242 -171.567671849506 43.5107607133321 -3.94310899273558 9.11270085745656e-05 VSIG2 other 1 1 1 -1.28935768780767 -3.94310899273558 0.0308581617914338 37.8805128990416 27.6405457064497 1.37046906748308 0.171105757680186 171.350096656104 67.3766789957889 2.54316625885958 0.0112610604916121 MARCO other 1 1 1 1.37046906748308 2.54316625885958 0.68880611074188 30.9188111105707 39.6853105103065 0.779099639463345 0.436274074244133 -93.3737960305483 311.034229901876 -0.300204244593932 0.764140881973344 CYP24A1 other 1 1 1 0.779099639463345 -0.300204244593932 9.18491720309503e-06 9.57820566903748 10.5008533924107 0.9121359294436 0.362107989572032 -114.3049485612 27.5613947982934 -4.14728461305152 3.912238213035e-05 PRDM11 other 0.0560647346076921 0.454249978915494 1 0.9121359294436 -4.14728461305152 0.520178808972021 152.554388952968 338.506320016943 0.450669248790784 0.652410874834328 -744.310099496587 895.377673166988 -0.831280611302191 0.406186665178895 SYT13 other 1 1 1 0.450669248790784 -0.831280611302191 0.0246022436415268 -29.2991486130894 13.9850296830009 -2.09503656961866 0.0367212567116399 -236.075996979732 116.536160341079 -2.02577462899742 0.043372265455963 SNAI2 other 1 1 1 -2.09503656961866 -2.02577462899742 0.790507236796267 816.304594430508 2049.55156083822 0.398284488191485 0.690576757541626 -1890.95758424175 4862.2483850852 -0.388906002836508 0.697497854764835 CD74 other 1 1 1 0.398284488191485 -0.388906002836508 0.0342482167281883 -17.8566103644801 7.79498941556781 -2.29078057871607 0.0223612351056391 -43.364042790937 24.8230563600459 -1.74692600951162 0.0812197385523063 HGF other 1 1 1 -2.29078057871607 -1.74692600951162 1.91346837151482e-13 157.805998874708 34.3864552910434 4.58919064320687 5.54325737606343e-06 -278.788629003341 66.2096255001346 -4.21069635868541 2.98410580251377e-05 ZRANB1 other 1.86276145966967e-09 0.349229902068186 0.0508760161975102 4.58919064320687 -4.21069635868541 0.000206476693451875 73.7146703290119 68.5363672045708 1.07555555299546 0.282610872574354 -426.809527183748 131.128968816464 -3.25488357787009 0.00120611588103059 NCDN other 1 1 1 1.07555555299546 -3.25488357787009 3.28639727307905e-07 89.3182395576629 19.530235780022 4.57333134959021 6.19654592942726e-06 -235.923385938389 125.285214787838 -1.88309040566286 0.0603257607583011 ADGRA2 other 0.00228667522260841 1 0.0566983952542594 4.57333134959021 -1.88309040566286 7.39980220334854e-21 68.5249922101862 6.88347092816281 9.95500568322666 1.68779539654045e-21 -32.6919287005443 49.7999071592035 -0.65646565556905 0.511812732701281 ZFP64 other 8.92046155613666e-17 1 2.35228044415842e-17 9.95500568322666 -0.65646565556905 7.27375276592452e-38 133.39609938808 12.1244180659597 11.0022682047397 1.48290264272637e-25 -110.29956612116 26.043837412017 -4.23515031123125 2.68262083532033e-05 MNAT1 essential 1.05491236364203e-33 0.314993338483313 2.13033793654071e-21 11.0022682047397 -4.23515031123125 0.0758564931024972 44.4639441231359 21.5520721053401 2.06309369724681 0.0395803090699555 77.9302777362994 48.3973775601316 1.6102169511039 0.107933786770077 SAMD4A other 1 1 1 2.06309369724681 1.6102169511039 0.225157491251589 91.1325628062791 54.4233119388151 1.67451335759819 0.0946044994661623 43.2920060183123 86.5592651381008 0.500142947716136 0.617176679464604 RUNX3 other 1 1 1 1.67451335759819 0.500142947716136 1.15371367388073e-33 250.710041972863 24.3462466611049 10.2976875845669 8.06350040915058e-23 -65.4652214037589 49.4824797294492 -1.3229979936676 0.186398067225181 MRE11 other 1.62973593572393e-29 1 1.13719546270251e-18 10.2976875845669 -1.3229979936676 7.56937220273054e-06 206.789706179402 45.1974869901853 4.57524787217277 5.96939133791912e-06 -27.6105742177325 157.878908748621 -0.174884501271128 0.861239254390147 PLEKHB1 other 0.046491084069171 1 0.0546736552640012 4.57524787217277 -0.174884501271128 8.87263392978991e-08 19.0720718881635 41.0354082980995 0.464771100840899 0.642286984156313 -683.218609896686 127.944151857069 -5.33997529375111 1.3834770475262e-07 SERPINB1 other 0.000643887044284854 0.00182051744683972 1 0.464771100840899 -5.33997529375111 1.48524399277494e-13 129.575816963494 17.0336635037202 7.60704336651917 1.24173494896218e-13 -20.9412985822752 53.133377900937 -0.394126995300742 0.693641729037946 SPAST other 1.45167747853823e-09 1 1.5429798475804e-09 7.60704336651917 -0.394126995300742 7.21566054202224e-05 1.34804689954451 13.9981528006846 0.0963017705792284 0.923316567351639 -115.941558055247 29.4289209844091 -3.93971488511833 9.22636595744963e-05 NRXN3 other 0.399710529363397 1 1 0.0963017705792284 -3.93971488511833 8.56850386136198e-11 49.6865114667076 33.318772553773 1.49124675545952 0.136481716122755 -389.899569441612 70.1480954276464 -5.55823457593045 4.29091009193836e-08 OSBPL5 other 7.41346954085038e-07 0.000574896134117901 1 1.49124675545952 -5.55823457593045 6.09836726352216e-30 157.373165456395 50.5664922680187 3.11220253566862 0.00195486801777675 -821.920909708084 92.4369344717853 -8.89169371966744 8.93725616480089e-18 AQR essential 8.33829755941385e-26 1.36561274198158e-13 1 3.11220253566862 -8.89169371966744 0.138232688118578 18.28604222246 24.5788543817555 0.743974553835735 0.457216066964394 -88.8486522766632 56.7091728424625 -1.56674216574246 0.11776184076436 CPS1 other 1 1 1 0.743974553835735 -1.56674216574246 6.89861362469253e-94 588.604954851008 23.2126979282174 25.3570247056676 2.52554322316569e-93 -316.558365257438 191.747771481366 -1.65091027036108 0.0993526549516734 RTFDC1 essential 1.07652865613327e-89 1 3.94237297136164e-89 25.3570247056676 -1.65091027036108 0.695332916368188 -53.5656315105288 79.0002558137232 -0.678043772881352 0.498031177809505 -136.070770939363 187.879358564512 -0.724245451863413 0.469225267802024 GABRA1 other 1 1 1 -0.678043772881352 -0.724245451863413 0.159681352631653 107.068359347301 59.9328867921062 1.78647091902476 0.074580842774157 221.762692305683 224.191115071529 0.989168068658426 0.323021482558474 NLRP2 other 1 1 1 1.78647091902476 0.989168068658426 3.40684769997184e-08 61.0252460843323 10.3997361808723 5.86796097737294 7.79598199076368e-09 -27.3163564464074 77.9941695072914 -0.350235878130015 0.7263013542312 SLC45A4 other 0.000255104755773891 1 8.37990104187188e-05 5.86796097737294 -0.350235878130015 2.60556798381091e-26 464.989145275687 76.8720387748196 6.04887229071385 2.71457427786697e-09 -1282.5057535033 171.962649822665 -7.45804833099441 3.49063546530446e-13 RNF10 other 3.42762468270326e-22 5.15322513742897e-09 2.96757260056417e-05 6.04887229071385 -7.45804833099441 3.25397619579089e-22 34.4100036646984 11.2771733915068 3.05129685162184 0.00239034087408927 -190.296206371624 23.5515446999845 -8.07998833179504 4.24835329093029e-15 ZNF839 other 4.02581934943249e-18 6.38145147830639e-11 1 3.05129685162184 -8.07998833179504 7.00764982168249e-15 105.651093189495 26.7409502422608 3.95091020447457 8.80691385158027e-05 -258.463607263491 50.4373394298587 -5.12444966735264 4.14706789702159e-07 ZDHHC6 other 7.20456478167176e-11 0.00535054700073725 0.731238057096709 3.95091020447457 -5.12444966735264 0.997594700333682 0.13066550292644 6.17077016687579 0.0211749100019706 0.983113892971271 -0.451024644466611 11.0456620060487 -0.0408327399679283 0.96744421974789 GRAMD1B other 1 1 1 0.0211749100019706 -0.0408327399679283 7.36838446687999e-18 267.71396725315 99.5057500045749 2.69043715806214 0.00735639051711391 -1243.23772896029 204.336120949111 -6.08427782217668 2.21586083984866e-09 RNH1 other 8.29164304058005e-14 3.07982498130565e-05 1 2.69043715806214 -6.08427782217668 3.30873454192882e-10 368.580314191221 72.7555135551728 5.06601212994964 5.56690942668503e-07 -505.550011274806 173.260428701119 -2.91786194380772 0.00366955824543946 NDUFS1 other 2.78066050903698e-06 1 0.00543998389175662 5.06601212994964 -2.91786194380772 2.81688249707638e-48 564.994229566179 34.7248214371766 16.2706158356596 8.14327155487578e-48 -328.169559196775 279.808164348114 -1.1728376831367 0.241436612331812 RB1CC1 other 4.23912646985024e-44 1 1.24469905716276e-43 16.2706158356596 -1.1728376831367 5.33572751192984e-09 267.801249998811 43.7101963134889 6.12674553273897 1.72787312295968e-09 62.902376404612 91.5418976886108 0.687143024045458 0.492287051145872 ERP44 other 4.19654968813282e-05 1 1.90377060687697e-05 6.12674553273897 0.687143024045458 4.97494275457526e-09 140.180002243181 29.295591787506 4.78502032865454 2.22975223230651e-06 -65.5011749994823 53.5720134086204 -1.2226752520924 0.222005177197128 ALAS1 other 3.92025489060531e-05 1 0.0210198742939535 4.78502032865454 -1.2226752520924 0.000238139721426429 55.1408423171569 76.9878994489411 0.716227390432008 0.474159426510214 -458.106144975882 155.144182224921 -2.95277681964084 0.00328583414698153 BIRC3 og 1 1 1 0.716227390432008 -2.95277681964084 6.01023851812938e-14 124.057457606209 59.0729920481666 2.10007066351161 0.0361833484860204 -629.308705949805 113.647637479089 -5.53736725117225 4.78832183611174e-08 AKAP11 other 5.96275763383616e-10 0.000640533812016668 1 2.10007066351161 -5.53736725117225 3.21436017760949e-16 35.0672094145325 4.01458606689315 8.7349502116094 3.22908195598827e-17 28.0122969786701 27.8596635660587 1.00547865239828 0.315126986424365 GLRX2 other 3.45061565066378e-12 1 4.29209573589961e-13 8.7349502116094 1.00547865239828 1.73010953833074e-15 56.8883720080602 6.68827163983767 8.50569101727467 1.78750107257142e-16 49.707178908041 13.8629155191077 3.58562229132305 0.000366832566057525 SNAPC1 essential 1.81453888380128e-11 1 2.34555890742822e-12 8.50569101727467 3.58562229132305 1.07873716542195e-34 212.077896647366 17.1410118660814 12.3725424324001 4.05710001485278e-31 -60.0858503731531 55.1292570981407 -1.0899085809589 0.276241342393037 DERA other 1.53525873382852e-30 1 5.99071388193161e-27 12.3725424324001 -1.0899085809589 1.84055565973372e-43 1059.7940070606 75.9060385241273 13.9619196004246 4.89839113847009e-38 -426.387830439194 242.68059024564 -1.7569918962518 0.0794869369266549 STRAP essential 2.73414543253444e-39 1 7.36962946782824e-34 13.9619196004246 -1.7569918962518 0.660686588695022 -20.4761652650327 40.5793263945198 -0.504595987275876 0.614046579498862 -71.74820575325 80.305745526449 -0.893438013468407 0.372016998375416 ABCC2 other 1 1 1 -0.504595987275876 -0.893438013468407 0.0191032332448609 32.090197670504 15.9051029625665 2.01760389392197 0.0441212460144014 -63.153881185728 53.016698192884 -1.19120736180068 0.234089756047077 DEF6 other 1 1 1 2.01760389392197 -1.19120736180068 0.00623890242882545 62.7932334881725 20.6121017495591 3.04642555383832 0.00243546192676195 197.641500634913 251.731523056301 0.785128132684081 0.432742298087794 PLEKHO1 other 1 1 1 3.04642555383832 0.785128132684081 5.45247047289251e-24 176.852446792304 17.0103415098032 10.3967605053892 3.45802184460463e-23 -12.882384938824 51.8078892797962 -0.248656818834112 0.803721497529849 GCLM other 6.93717818266114e-20 1 4.89137189919324e-19 10.3967605053892 -0.248656818834112 1.4071440311901e-56 497.873213883582 29.0481329916975 17.1395942736108 7.26187533800085e-53 -219.751086535782 138.19284757044 -1.5901769910615 0.112382333568947 UBR2 other 2.15250822451149e-52 1 1.11600500194397e-48 17.1395942736108 -1.5901769910615 0.00230676315440607 -51.0827633046895 136.370601379406 -0.374587798161634 0.70811329291776 -1308.82793809856 383.522387226672 -3.41265068660778 0.000691311349755099 EHD2 other 1 1 1 -0.374587798161634 -3.41265068660778 2.9595181407176e-12 249.922533806569 33.7743601277164 7.39977109444846 5.26805338571732e-13 103.160968570459 66.2779993352969 1.55648887421259 0.12017882684414 DEPDC1 other 2.7467287864e-08 1 6.44440970674799e-09 7.39977109444846 1.55648887421259 2.17502385899113e-11 8.78657478104421 14.1068829229207 0.622857283855946 0.533648766512938 -194.044710311378 32.1043703585004 -6.04418364679126 2.85003404926217e-09 CCDC28A other 1.9392512726765e-07 3.95100220249215e-05 1 0.622857283855946 -6.04418364679126 7.47458559792704e-08 150.376456929522 27.5451300489134 5.45927562013649 7.29400165138192e-08 78.5368102349298 62.9869308421211 1.24687469582833 0.212982996430855 RRAGD other 0.000545495256936715 1 0.000751355110108851 5.45927562013649 1.24687469582833 2.89862957548343e-40 92.5730840377601 8.82883963698291 10.4853058662412 1.66131984649933e-23 -83.5501836619073 20.21751923766 -4.13256357912968 4.16775793842655e-05 HSF2 other 4.2499706835738e-36 0.483084822643021 2.35575154233605e-19 10.4853058662412 -4.13256357912968 3.79517685388476e-17 231.9410933082 31.0635892984946 7.46665464442774 3.42165016132093e-13 -642.640547566212 169.723916568914 -3.78638768511611 0.000170403255738171 PHF20 other 4.18797765826183e-13 1 4.20589237829568e-09 7.46665464442774 -3.78638768511611 0.211456062648976 5.68799372342103 6.07730111280364 0.935940743735337 0.349725182721349 -21.5237105874349 17.8947234956246 -1.20279648873578 0.229586117944821 HSD17B6 other 1 1 1 0.935940743735337 -1.20279648873578 4.09088429369279e-05 47.3196875240133 21.4946800774286 2.20146042432627 0.0281256791552565 -182.542978871589 61.8994302302156 -2.94902518799732 0.0033258541395004 NR1H3 other 0.234121308128039 1 1 2.20146042432627 -2.94902518799732 0.00225931064614682 258.448287084114 128.801306015522 2.00656573352579 0.0453082236261093 -496.566797271457 275.767745358311 -1.80067033084764 0.0723286589907153 TYMP other 1 1 1 2.00656573352579 -1.80067033084764 4.73468328675581e-29 373.863065939592 33.7744535486231 11.0694038439841 9.67148477426459e-26 -3.80912789303978 72.3121930509805 -0.052676149516781 0.958009979522722 NCAPH2 essential 6.42354481514161e-25 1 1.39124308477796e-21 11.0694038439841 -0.052676149516781 1.10443289147609e-32 265.746219646487 20.5799935831519 12.9128426873779 1.96131267434393e-33 13.6827549278938 137.040600397249 0.0998445343075748 0.920504806889553 TOMM34 other 1.54874624371692e-28 1 2.9180409968889e-29 12.9128426873779 0.0998445343075748 1.87606685092972e-81 1341.87816297086 64.5658113911134 20.783106942501 1.49983377391915e-70 -22.7084071398206 185.171395866666 -0.122634530206663 0.902443172581189 SEC63 essential 2.91897241336155e-77 1 2.32834195063209e-66 20.783106942501 -0.122634530206663 5.78140767043585e-20 368.939810969563 63.097472692197 5.84714086361795 8.69918201205158e-09 -554.820043573186 117.228745517202 -4.73279860775932 2.83722897879127e-06 KPNA6 other 6.84229597796083e-16 0.0352922912671846 9.33335238073014e-05 5.84714086361795 -4.73279860775932 0.306992089998938 624.522604993708 995.583120810492 0.627293283643953 0.530728753038235 6395.34361743975 4284.1430189609 1.49279414555841 0.1360676144192 VIM other 1 1 1 0.627293283643953 1.49279414555841 0.1101065501616 12.0619143610833 20.2700420204652 0.595061142394538 0.552052797804304 86.6521158754369 41.2526180944937 2.10052403648541 0.0361476014824118 FAS ts 1 1 1 0.595061142394538 2.10052403648541 5.68480224810085e-19 320.375473960465 65.7903756073179 4.86964044517219 1.46698527661208e-06 -667.198481770156 138.008378022025 -4.83447810439214 1.73878737955604e-06 RNASET2 other 6.56651507678129e-15 0.0218322143377057 0.0139686338039002 4.86964044517219 -4.83447810439214 0.0222604954048818 650.711671526237 501.779237260646 1.29680868239717 0.195262372186483 -3050.03324540243 1484.41937157389 -2.05469781909985 0.0403988179022355 CD44 other 1 1 1 1.29680868239717 -2.05469781909985 2.30673135101516e-06 44.6217674572922 16.0651774403584 2.77754588288548 0.00567225010666737 584.263209173973 126.147539345959 4.63158625370912 4.57699018546041e-06 KCNG1 other 0.014908404721611 0.0563335952026467 1 2.77754588288548 4.63158625370912 0.0168928989291984 24.8416766762742 10.4309745390571 2.38152979697713 0.0175819528646089 -5.78910889557274 21.8356979549368 -0.265121312243829 0.79101588799855 AGPAT4 other 1 1 1 2.38152979697713 -0.265121312243829 0.388872157960181 3.80506973655083 14.5807142777544 0.260965935143259 0.794217902155276 195.974835805475 145.635178673548 1.34565588884789 0.178976158681936 SLAMF7 other 1 1 1 0.260965935143259 1.34565588884789 0.00267486574794652 94.0634965668267 29.9345481521336 3.14230554237119 0.00176959161082756 -62.4717793606539 120.572838077213 -0.518124814484734 0.604586592487121 BTN3A1 other 1 1 1 3.14230554237119 -0.518124814484734 1.69815468775172e-19 124.739904927418 28.7108715916506 4.34469237651751 1.66442149310912e-05 -315.212816908609 57.9875876790705 -5.43586704542943 8.24454262002719e-08 MIPEP essential 1.99006747857624e-15 0.00109454547823481 0.147251369495364 4.34469237651751 -5.43586704542943 1.49838981482357e-09 40.720424774501 29.5388722347101 1.37853688018095 0.168610530942356 -330.333389660037 62.1020578444591 -5.31920198985017 1.53124921845393e-07 PRKCH other 1.21609317371081e-05 0.00201007084906448 1 1.37853688018095 -5.31920198985017 1.22295690584769e-05 104.896803516347 57.596184623465 1.82124569886199 0.0691352706488942 -408.034077679373 130.711465145002 -3.12163953809811 0.00189694436188665 IFNGR1 other 0.0737687605607326 1 1 1.82124569886199 -3.12163953809811 3.10816618714831e-17 89.3359081532759 15.6794378721497 5.69764738262441 2.00409702128243e-08 -204.714830588091 44.3317572597129 -4.61779192258928 4.85892934204627e-06 B4GALT7 other 3.43763180298603e-13 0.0597308184017748 0.000211893178060191 5.69764738262441 -4.61779192258928 0.00678670535297604 10.699151887867 3.63869698845751 2.9403800101537 0.00341776962180383 40.3119985497682 32.4696743917021 1.24152765018396 0.214946914968732 SH2D2A other 1 1 1 2.9403800101537 1.24152765018396 0.0571791173766034 160.409030767526 68.3509669643146 2.3468436203876 0.0192902477717385 -39.6133301179531 243.276730293928 -0.162832384626726 0.870710766649607 VRK2 other 1 1 1 2.3468436203876 -0.162832384626726 1.46026155499692e-16 238.448568404213 47.8989523668964 4.97815832333335 8.64776518178235e-07 -737.326707573292 129.300514503071 -5.70242671041947 1.94658108240766e-08 VEZT essential 1.58248544715016e-12 0.000263586544368822 0.00835460594211993 4.97815832333335 -5.70242671041947 0.439247369682806 -2.74215767661934 7.06416410513644 -0.388178648713085 0.698037955622111 -28.8773692157554 22.5024631878839 -1.28329814272528 0.199942202922138 POU2F2 other 1 1 1 -0.388178648713085 -1.28329814272528 2.7165495322198e-22 160.20725314478 15.8227725831335 10.125106222885 4.00498422021787e-22 -80.5745541420903 72.4657731950703 -1.11189808083869 0.266692824578896 BRD9 other 3.36526156051388e-18 1 5.61098289252524e-18 10.125106222885 -1.11189808083869 8.00142655612561e-35 841.26747818298 86.0001028784828 9.78216827684127 6.66044081045048e-21 -1204.75368426457 191.222093677966 -6.30028497801869 6.20111104370867e-10 SNX1 other 1.13980321292009e-30 8.73054423843744e-06 9.23669931593273e-17 9.78216827684127 -6.30028497801869 2.4983177758308e-20 88.3289907043658 10.6360743500151 8.3046608925069 8.30577829140598e-16 -22.0539540523345 24.3582125187892 -0.905401167483972 0.365661978858228 TBPL1 other 2.97774495701274e-16 1 1.07709332882953e-11 8.3046608925069 -0.905401167483972 6.31859232253333e-10 207.640825781865 31.3841941346912 6.61609550625183 8.90937577236356e-11 292.539641684445 172.146555752078 1.69936389610813 0.0898276301302377 ARNTL2 other 5.23116258382534e-06 1 1.02778558909986e-06 6.61609550625183 1.69936389610813 6.20522779479709e-10 171.861975473297 69.8519639474222 2.4603742795644 0.0141977480015414 -701.883508723681 161.806700419615 -4.3377901341754 1.72410920496112e-05 BCLAF1 essential 5.13979018243043e-06 0.205186236482422 1 2.4603742795644 -4.3377901341754 1.30141476220677e-35 325.996207007263 95.0953943515674 3.42809669416855 0.000654643981670535 -1905.09602336191 186.311937702159 -10.2253030420811 1.54435473178836e-22 SLC39A9 other 1.86479721276608e-31 2.39529418900375e-18 1 3.42809669416855 -10.2253030420811 0.0602676047427089 43.250254641253 21.7586356235989 1.98772824681823 0.0474953308162642 -53.3610822299916 95.620818829761 -0.558048789824665 0.577110545098332 ANK1 other 1 1 1 1.98772824681823 -0.558048789824665 0.251389826505584 12.2990260848231 8.71607848588525 1.41107335193688 0.158790437058161 -6.24553380495131 21.0780976333058 -0.296304434755186 0.76710985672757 IBSP other 1 1 1 1.41107335193688 -0.296304434755186 2.7224318211525e-37 40.1749639140961 4.85834996932534 8.26926099761294 1.0470242302698e-15 -58.7278745970555 10.19818666285 -5.75865852808812 1.42153831960628e-08 TFB1M other 3.93554744065805e-33 0.000193471365298414 1.35474465154609e-11 8.26926099761294 -5.75865852808812 1.11807714284112e-48 767.254636715911 205.058612716444 3.74163575258784 0.000202177305630984 -4890.91795430114 375.320278548048 -13.0313181403946 5.44474729689966e-34 RABEP1 other 1.68505406197586e-44 8.529741115323e-30 1 3.74163575258784 -13.0313181403946 9.2516848254244e-20 468.783853801809 53.0225803307242 8.84121162866473 1.40208031827345e-17 -142.397677994242 154.026714144358 -0.924499875137134 0.355646838542718 NUP160 essential 1.0910511914623e-15 1 1.87317930521334e-13 8.84121162866473 -0.924499875137134 1.53168227291363e-12 122.225703623612 17.0017718227927 7.18899799959408 2.21299429313166e-12 9.35533250624392 57.00734224842 0.164107501547368 0.869708611510729 BAK1 other 1.43733064490215e-08 1 2.66931371637541e-08 7.18899799959408 0.164107501547368 0.0502278840555549 -16.1988104092074 41.1110451875655 -0.3940257499001 0.693716431768109 -230.923230789703 94.9662853106188 -2.43163381651069 0.01535264470106 IKZF2 other 1 1 1 -0.3940257499001 -2.43163381651069 2.93294752613974e-11 1113.40524722262 217.356764999675 5.12247800165909 4.21108558943383e-07 -1306.2224897369 509.432869426082 -2.56407186919145 0.0106161275253255 GRN other 2.60005798192288e-07 1 0.00415339371685859 5.12247800165909 -2.56407186919145 4.29587966509926e-16 44.0235388753134 30.9489885371924 1.42245485090438 0.155467381650225 -539.298174093821 71.7990720040749 -7.51121371127489 2.41839709812708e-13 FAM13B other 4.59272494995761e-12 3.57560010958089e-09 1 1.42245485090438 -7.51121371127489 0.525432741935923 -20.2970676611389 30.1987259830883 -0.67211668705844 0.501796342976391 -97.4963895807319 96.4944031553956 -1.01038388126742 0.312763082606468 ARHGAP31 other 1 1 1 -0.67211668705844 -1.01038388126742 5.30039102744107e-28 41.2684346212128 3.70821323474335 11.1289270623805 4.77746418827452e-26 -22.9018109572153 17.9160605954601 -1.27828385236756 0.201697502092569 CENPQ other 7.11100460241493e-24 1 6.88384814888476e-22 11.1289270623805 -1.27828385236756 1.03971925422803e-38 747.040854767201 72.1029301445449 10.3607558426489 4.51380989620605e-23 -863.880556827926 173.856070471886 -4.96894100092769 9.04056282072978e-07 SARS essential 1.51351931837975e-34 0.011508636470789 6.37665924037029e-19 10.3607558426489 -4.96894100092769 1.74422612725312e-32 175.725112107483 26.5703000511099 6.61359155784702 8.99432303578621e-11 -520.262723175676 63.3953339768089 -8.20664062383514 1.6612386848457e-15 RANBP3 other 2.4420910007671e-28 2.50431731740489e-11 1.03740521894758e-06 6.61359155784702 -8.20664062383514 6.37814557033282e-22 37.5729005744802 18.1627559231623 2.06867838413029 0.0390472680687591 -332.625970404203 38.2515089193599 -8.69576076346244 4.06293820819461e-17 ARID4A other 7.84639468062344e-18 6.18663600961793e-13 1 2.06867838413029 -8.69576076346244 3.53736076783853e-95 886.025345922237 35.1305655727173 25.2209246130194 1.08513360107236e-93 180.941986491644 125.884864772829 1.43736093150015 0.151187236043798 PNPLA6 other 5.52146642251915e-91 1 1.6944361180745e-89 25.2209246130194 1.43736093150015 4.60147173308154e-34 28.6477640181227 13.0884228102184 2.18878656607555 0.0290537824626658 -269.359080178766 25.827021071706 -10.4293514699554 2.89988168353043e-23 IFT88 other 6.51936515142993e-30 4.50293627818605e-19 1 2.18878656607555 -10.4293514699554 1.77596298412407e-41 220.024722427531 18.0777139093072 12.1710479284802 2.64759082814277e-30 -391.60999217373 87.9852149047513 -4.45086134753059 1.03837005660761e-05 ALG1 essential 2.61723664970364e-37 0.125258579928576 3.89645942177771e-26 12.1710479284802 -4.45086134753059 1.14563547075131e-12 59.2781443515689 16.3365292748435 3.62856414323273 0.000312020558421906 -191.895585903963 36.0599856462078 -5.32156578726046 1.50934283731248e-07 ZCCHC8 other 1.08010512182434e-08 0.00198252181680995 1 3.62856414323273 -5.32156578726046 6.34297023386704e-27 240.644917037016 27.8089569412085 8.65350388890059 5.6533310539166e-17 -378.820301799371 85.4459120352659 -4.43345144052089 1.12231614633933e-05 ABCF2 other 8.40869569352082e-23 0.135081971373402 7.48727164780714e-13 8.65350388890059 -4.43345144052089 5.73048406120386e-17 143.247820050931 95.8869447139832 1.49392412573181 0.13578278574634 -1406.48016547294 190.564907516151 -7.38058325536008 6.03370339550948e-13 FUT8 other 6.28748711195288e-13 8.88402487954816e-09 1 1.49392412573181 -7.38058325536008 4.13464067975655e-16 338.980320729952 43.2865920660535 7.83106972738076 2.64623630087711e-14 -48.6210290726102 106.446708841384 -0.456764042794975 0.648027439920378 UBA6 other 4.42323859920356e-12 1 3.33796246992638e-10 7.83106972738076 -0.456764042794975 1.4640521833027e-30 303.546564763853 25.1868010677118 12.0518109444627 1.37607800989429e-29 -27.4162892440134 122.21665399596 -0.224325313675497 0.822594552667882 GAB2 other 2.01336456247787e-26 1 2.01898165611691e-25 12.0518109444627 -0.224325313675497 4.86619994641997e-26 279.449825353942 30.7648138200872 9.08342325710684 1.97853309132624e-18 -263.297677959937 66.8794976941168 -3.93689676265464 9.33435758733547e-05 PIAS1 other 6.38202122972979e-22 1 2.67299820638174e-14 9.08342325710684 -3.93689676265464 6.47688405877675e-07 344.774563497712 141.673921503228 2.43357817613495 0.0152743271904906 -1074.73300803447 294.507163735958 -3.64925930629662 0.000288584909216863 SLC4A7 other 0.00439780427590942 1 1 2.43357817613495 -3.64925930629662 2.71235412986323e-11 63.0275872899157 18.6494584344215 3.37959343492704 0.000778081884046933 251.049449028227 35.1861267420453 7.1348986738071 3.11408729253733e-12 APBA2 other 2.40694305484063e-07 4.55154998677257e-08 1 3.37959343492704 7.1348986738071 3.03108335708555e-28 307.833702036521 27.5180089203348 11.1866270167913 2.67891657050704e-26 110.573978969179 74.0306384566194 1.49362454889503 0.135851418004093 MAP2K3 other 4.07771644028719e-24 1 3.86594450289871e-22 11.1866270167913 1.49362454889503 0.981473486861089 -0.159148417638546 1.53523825852632 -0.103663660513068 0.917482244512409 -2.23804477759113 12.7265039510243 -0.175856997821542 0.860485046709269 EFCAB1 other 1 1 1 -0.103663660513068 -0.175856997821542 4.19745706152141e-08 6264.00009487541 1171.57506122122 5.34664854366735 1.31997330258104e-07 -7415.7486799432 4206.53250582396 -1.76291248663265 0.0784756495202057 TMSB10 other 0.000311996983382887 1 0.0013380569368264 5.34664854366735 -1.76291248663265 5.09021939843657e-19 34.0989922324189 4.90883449231848 6.9464538447524 1.07340516821043e-11 -86.6832198364958 16.6795714063525 -5.19696925806393 2.86993558851631e-07 ASTE1 other 5.88887482205127e-15 0.00372546338745303 1.27284384846393e-07 6.9464538447524 -5.19696925806393 6.85978441805618e-23 335.295417213941 31.8760801433448 10.5187154664607 1.19772469276873e-23 -401.255946537513 462.069037824175 -0.868389599153791 0.385570456210984 RNF19A other 8.58090432854648e-19 1 1.70040974632376e-19 10.5187154664607 -0.868389599153791 2.80761449969053e-34 65.5893930176578 8.42828495933965 7.7820568875019 3.73932476501372e-14 -106.352022965863 18.3823664442655 -5.78554579946588 1.23477190731565e-08 PEX3 other 3.98597030521065e-30 0.000168361149562489 4.70444448686376e-10 7.7820568875019 -5.78554579946588 7.6440606043547e-49 338.771121160851 40.0919504527671 8.44985383187984 2.65835588671521e-16 -553.699086801631 87.6413884861419 -6.31778086091348 5.50974289895145e-10 GABARAPL2 other 1.15241857671252e-44 7.76377871891249e-06 3.47792700658951e-12 8.44985383187984 -6.31778086091348 0.694374130097206 -75.3631010421947 94.2285940343957 -0.799790146658512 0.424183422220967 -242.067866444632 687.662299726888 -0.352015613682431 0.724963628332252 MYOC other 1 1 1 -0.799790146658512 -0.352015613682431 2.56333793213605e-07 206.130926811093 48.3278282122966 4.26526360558955 2.35396754728676e-05 -387.360721245738 149.834403354949 -2.58525887628158 0.00998916186288455 SH3YL1 other 0.00179818155939344 1 0.205807382659282 4.26526360558955 -2.58525887628158 6.36081754287696e-14 255.833363727693 33.6572345375959 7.60114035637483 1.29402938399761e-13 -141.095071795411 112.072760221594 -1.25895955017467 0.208584904205172 FAM136A other 6.30547843025393e-10 1 1.60705509198663e-09 7.60114035637483 -1.25895955017467 5.15847582882408e-05 623.065782195823 147.426292894051 4.22628670886809 2.796780583634e-05 -40.8319229686228 377.171959522512 -0.108258108636482 0.913831845573087 VCL other 0.29088645198739 1 0.242984297106122 4.22628670886809 -0.108258108636482 2.02634169054967e-09 16.0987271192655 9.89507140906246 1.62694400613637 0.10433668325199 145.442839726156 22.8736581346233 6.35852992425393 4.36473608344978e-10 DEPDC1B other 1.63464984176642e-05 6.16257087622274e-06 1 1.62694400613637 6.35852992425393 1.51007824791262e-06 90.1157011561445 17.3658429039224 5.1892500499236 2.9968066056769e-07 27.3287942636441 38.5568257857022 0.708792638054201 0.478760176782753 DAPK2 other 0.00991970401053799 1 0.00298122321132738 5.1892500499236 0.708792638054201 1.89873263812031e-23 116.586942437634 10.8833629772825 10.7124004483717 2.62787854789938e-24 14.5354714833669 92.4342758669125 0.157251964674827 0.875108026851003 NSMAF other 2.39582084278021e-19 1 3.74656644574015e-20 10.7124004483717 0.157251964674827 1.27191105835752e-19 340.636100776193 35.8204464627354 9.50954369400622 6.11758659078496e-20 -339.191591961447 225.054933486831 -1.50715021753253 0.132352625612303 ADSS other 1.49500425799343e-15 1 8.40678749305669e-16 9.50954369400622 -1.50715021753253 0.767456785641195 -1.03663802573066 1.51659723660076 -0.683528890013104 0.494571409560191 -1.84358898777526 3.70984597555555 -0.496944886640254 0.619433985103097 STAP1 other 1 1 1 -0.683528890013104 -0.496944886640254 0.986278202296622 -45.5995280628095 304.595413294298 -0.149705235445392 0.881052970070527 -85.0276040975227 864.586923130121 -0.0983447723101012 0.921694953417656 TIMP2 other 1 1 1 -0.149705235445392 -0.0983447723101012 4.52575836857056e-16 225.985546475188 49.1629481126193 4.59666385257278 5.33854852368896e-06 -407.809750989064 99.5105220274163 -4.09815708610902 4.79707730451103e-05 RFC1 other 4.83396251347021e-12 0.554302282536249 0.0490665994812252 4.59666385257278 -4.09815708610902 7.53033527381078e-21 252.045667431172 26.4554743256213 9.52716493867866 5.25962870320564e-20 -180.481372763007 93.0081760627006 -1.94048932473783 0.0528356043993813 TBC1D23 other 9.07556007199675e-17 1 7.2330413926484e-16 9.52716493867866 -1.94048932473783 2.31016872789101e-23 237.742759765386 50.7126209815717 4.6880392920685 3.49129676779391e-06 -858.563046105815 107.787157532411 -7.96535566723387 9.69521822975036e-15 CUL3 essential 2.91058158026988e-19 1.4524406429989e-10 0.0324620773469478 4.6880392920685 -7.96535566723387 0.191057704750083 59.9206890111899 182.176388609246 0.328915780297495 0.74235305608825 -450.39786393911 380.161028072072 -1.18475548696623 0.236660583007305 MYOM2 other 1 1 1 0.328915780297495 -1.18475548696623 0.0131901150348497 0.130677413955886 1.50966990024923 0.0865602566059722 0.931052966892356 -8.37241072098282 3.10172170346546 -2.69927850446047 0.00716552827179632 CYP46A1 other 1 1 1 0.0865602566059722 -2.69927850446047 2.09439003141466e-13 277.633379768557 51.6704502607325 5.37315580506073 1.15480324285221e-07 -327.449948987826 102.66935133156 -3.18936415532967 0.00150904501671792 ZZZ3 other 2.03532823252877e-09 1 0.00117408845700784 5.37315580506073 -3.18936415532967 0.00100699019621442 41.4173769064241 14.8985693464889 2.77995664840026 0.00562550527990528 -12.6876295813151 27.4625773941558 -0.461997044167279 0.644268823375735 USP2 other 1 1 1 2.77995664840026 -0.461997044167279 9.32351852862348e-32 81.3770912654267 13.8171564974258 5.88956861569799 6.83349975383497e-09 -250.765159583216 30.8172936299639 -8.13715709738363 2.83047303317456e-15 TUBG2 other 1.29671495696095e-27 4.26071105683767e-11 7.3665127346341e-05 5.88956861569799 -8.13715709738363 2.45384350971257e-19 60.7745734240489 7.28156043491864 8.3463666843449 5.99288174625671e-16 -32.0879427100324 20.1576800323186 -1.59184701109385 0.112007537031049 RPL26L1 other 2.86559845064234e-15 1 7.79494128735611e-12 8.3463666843449 -1.59184701109385 0.00149922971648741 -16.3358675690468 12.7965646630735 -1.27658227025465 0.202312005792106 -123.557386862814 34.0531425019735 -3.62836959483704 0.000312990249011702 FLT4 other 1 1 1 -1.27658227025465 -3.62836959483704 2.26219375082777e-21 473.074092315728 46.8383856412831 10.1001365832465 4.33751692490269e-22 -3.35877890406001 212.203464145678 -0.0158281059057273 0.987377361304493 NSUN2 other 2.75263735600723e-17 1 6.07339119824875e-18 10.1001365832465 -0.0158281059057273 1.29378291907422e-35 67.6168814730742 15.423741124572 4.38394815673816 1.39890591056224e-05 -205.353329154113 23.8195917214079 -8.6211943326279 7.2197490047457e-17 FBXO42 other 1.85399092303336e-31 1.09754624370144e-12 0.124558582276462 4.38394815673816 -8.6211943326279 2.68532189578154e-08 38.4951116991176 21.4803594623062 1.79210742570062 0.0736723796123148 -238.088600453501 49.6324877160745 -4.79703136815346 2.08336032252787e-06 MFAP3 other 0.000202526977379844 0.0260690877157912 1 1.79210742570062 -4.79703136815346 1.16629089593121e-28 177.690008303154 17.3433588506018 10.2454207304249 1.28801191646396e-22 -217.101247843372 63.2565117192918 -3.4320774564172 0.000645226744873389 MRI1 other 1.57577562949265e-24 1 1.8119751640815e-18 10.2454207304249 -3.4320774564172 3.0778859705522e-15 99.4199286130291 12.9006527280318 7.70658126445024 6.56089919654643e-14 -52.2589255249614 36.8278047301668 -1.41900734805826 0.156493686688816 METTL1 essential 3.20254035235957e-11 1 8.20571662512062e-10 7.70658126445024 -1.41900734805826 0.00340828975836603 13.3767958058684 4.02206153691772 3.32585558005153 0.000941845869773491 3.57503370622418 12.460359704805 0.28691256038504 0.774290148624084 HOXC8 other 1 1 1 3.32585558005153 0.28691256038504 1.02556538067066e-14 69.2742303332197 21.8693332536426 3.16764253988773 0.00162385567353965 -247.703131219308 45.1249409197431 -5.4892732526755 6.22220099427667e-08 AGA other 1.04669202751247e-10 0.000829108282487367 1 3.16764253988773 -5.4892732526755 3.63551165278521e-09 147.743316692759 23.4157267625756 6.30957638816026 5.82616582559285e-10 110.336381764178 42.4410338603464 2.59975716254329 0.00958377887306237 PI4K2B other 2.88950466163369e-05 1 6.54569730505357e-06 6.30957638816026 2.59975716254329 3.78504882005121e-13 40.6523171096887 57.3458555500473 0.708897211834433 0.478692501624724 -707.246441746476 109.947373031148 -6.43259063175722 2.75507774149916e-10 BOD1L1 other 3.63516088677719e-09 3.90670023744581e-06 1 0.708897211834433 -6.43259063175722 7.04957032278281e-16 146.201818828566 33.2568671848523 4.39613923993291 1.32518136474095e-05 -427.578560451721 79.6100103100734 -5.37091452175855 1.16189594541684e-07 MAT2B other 7.49087342498901e-12 0.00153428359592294 0.118259184989482 4.39613923993291 -5.37091452175855 0.0939294708694847 2.73244562994693 9.55042598336266 0.286107199271215 0.774905742001047 -39.8500536678946 20.9567049129067 -1.90154195678692 0.0577630246874175 TLL1 other 1 1 1 0.286107199271215 -1.90154195678692 8.52093434709986e-60 343.39082976913 32.1248725071058 10.6892511306675 2.80099905409346e-24 -450.325692663932 71.9257020591235 -6.26098431814764 7.91894066771951e-10 EDC4 essential 1.30873030637107e-55 1.11205683796785e-05 3.99282415161022e-20 10.6892511306675 -6.26098431814764 8.37556697878521e-07 301.482034694565 69.1689812323852 4.35863054975008 1.565746724875e-05 -872.653059910063 350.777063742341 -2.48777115185347 0.0131535371928125 TRIO other 0.00563508146332669 1 0.138756474758422 4.35863054975008 -2.48777115185347 0.0729023449527486 -1068.41868605771 635.462320727373 -1.68132499946616 0.0932748251744316 -3041.89985799056 1450.36928985833 -2.09732781799847 0.0364263519421528 VCAN other 1 1 1 -1.68132499946616 -2.09732781799847 1.12659848572043e-33 168.980764992692 14.739895965639 11.4641762320855 2.1543975790796e-27 -224.57259187365 76.7147442694746 -2.92737196756855 0.00356194867751737 CLEC16A other 1.59154568077725e-29 1 3.12861616433939e-23 11.4641762320855 -2.92737196756855 0.576518789710476 -25.0066313101455 62.1795189795163 -0.402168297866431 0.687720494264985 65.1912389993743 127.846889937099 0.509916502712334 0.610319854748496 MSR1 other 1 1 1 -0.402168297866431 0.509916502712334 3.5376330427449e-43 4774.87893307295 630.635049297652 7.57154068488709 1.60290448465339e-13 -8708.02869587808 1410.83022062429 -6.17227258714714 1.32133313828532e-09 CDH1 ts 5.25055496204198e-39 1.84616666081225e-05 1.98712068962481e-09 7.57154068488709 -6.17227258714714 1.62776208024984e-32 193.548224931078 41.1146924563222 4.70751970567924 3.18837685502208e-06 -864.802487105785 95.2451357704203 -9.07975488837889 2.01728988719069e-18 SKIV2L2 essential 2.2796807933899e-28 3.09028637818742e-14 0.0297188606656608 4.70751970567924 -9.07975488837889 0.00464867287543252 -14.3052816108747 29.3163764983961 -0.487962133098452 0.62577363200239 -486.855899038437 147.817843699848 -3.29362062693205 0.00105348077183529 DNAH5 other 1 1 1 -0.487962133098452 -3.29362062693205 1.19086268771688e-24 68.3753965368163 37.5730394674744 1.81979944944317 0.0693389992559884 -782.513054291657 84.4017477975658 -9.27128969139931 4.28478773794435e-19 ZFYVE16 other 1.53109215759759e-20 6.5754352626494e-15 1 1.81979944944317 -9.27128969139931 7.52897966199641e-12 121.507041987936 36.0291431642226 3.37246549089721 0.000799827608779263 -259.54989955183 79.1539126517246 -3.27905331343308 0.00111046829574086 RIPOR1 other 6.86793524767312e-08 1 1 3.37246549089721 -3.27905331343308 0.219120997533813 -3.43745934954689 7.25804797810939 -0.473606589528538 0.635972240536403 -59.2736331748775 34.1241406644406 -1.73700002463782 0.0829584415945724 C6 other 1 1 1 -0.473606589528538 -1.73700002463782 0.198890615045999 82.209972384622 48.0578163523152 1.71064727081928 0.0877184683933826 184.422615332829 226.401861871867 0.814580824592353 0.415670049809072 RAI14 other 1 1 1 1.71064727081928 0.814580824592353 1.06087182633774e-06 155.088287212336 46.1912444336305 3.35752563313538 0.000841955925342338 -464.526553008934 153.044756107986 -3.03523338415575 0.00251955565923183 PNKP essential 0.00706328461975667 1 1 3.35752563313538 -3.03523338415575 7.9408383188518e-36 151.10310495958 16.5351727275569 9.13828403544632 1.27639620395773e-18 -109.952123040547 36.1414847340915 -3.04226912229843 0.00246216574401671 PHLPP2 other 1.1397485239048e-31 1 1.72862337901995e-14 9.13828403544632 -3.04226912229843 2.36109599951313e-09 57.7830891837346 11.3067588704542 5.11049097674916 4.45038981048093e-07 159.546572597554 29.0669360135433 5.48893672601804 6.20013672396886e-08 SPDL1 essential 1.89690452600885e-05 0.00082629222120333 0.00438096372943743 5.11049097674916 5.48893672601804 8.49201277905579e-40 350.677245247058 24.1325802745544 14.5312785146649 2.02577571104903e-40 -183.238874841643 243.062009771401 -0.753877066243213 0.451262956813024 STAU2 other 1.24272115008702e-35 1 3.06418834053277e-36 14.5312785146649 -0.753877066243213 8.63997908859499e-14 54.627578833103 15.3348666277382 3.56231196261538 0.000399685426440484 -109.80999787481 25.7165694892294 -4.27000957187545 2.30465927194537e-05 PQLC2 other 8.52161137508124e-10 0.271788467940517 1 3.56231196261538 -4.27000957187545 1.20935152321184e-34 51.1746359292109 8.62619635564091 5.93246824201334 5.29120828803159e-09 -137.561261983927 15.9407227004223 -8.6295498999103 6.6893538216989e-17 CTNS other 1.72090721753045e-30 1.01711624858932e-12 5.72561648847898e-05 5.93246824201334 -8.6295498999103 1.73240628518944e-08 49.8091397602181 8.32742016219692 5.98134101439138 4.05148480101414e-09 35.8101098871616 16.9630654054448 2.11106359795484 0.0352301179288148 RTN4R other 0.000132147951434251 1 4.39869704846105e-05 5.98134101439138 2.11106359795484 6.90895379758037e-48 106.902729168796 21.0653404791056 5.07481610728442 5.34457240441019e-07 -458.177057479278 38.3412057202158 -11.9499908485585 2.28569325367822e-29 PHF23 other 1.03931391977002e-43 3.5750528180781e-25 0.00523073301219625 5.07481610728442 -11.9499908485585 5.95033337185881e-07 67.1142267440403 14.9447403429859 4.49082588280225 8.66499571414108e-06 -112.319119365295 51.5966507532343 -2.17686841540301 0.0299188404097705 INPP4A other 0.00405039192622429 1 0.0784788661829758 4.49082588280225 -2.17686841540301 3.88165805169446e-07 -138.346792620283 107.169320111381 -1.290917890274 0.197286586155772 -1204.54685957179 223.50203228687 -5.38942240142914 1.05913998816073e-07 RAB27B other 0.00268494287435706 0.00140039489234612 1 -1.290917890274 -5.38942240142914 1.13576772344774e-43 1136.57242823348 73.6028587171848 15.4419603809236 7.78124301683176e-45 609.066510759632 177.384873701645 3.43358764504385 0.000641284959360991 PSMA4 other 1.68820514413272e-39 1 1.18461643688247e-40 15.4419603809236 3.43358764504385 0.000173016018780635 11.9960653570818 3.91566565176781 3.06360818924003 0.00229637855403858 -15.2537094045171 9.28798027997189 -1.6423063943632 0.101110855037243 MYO16 other 0.91023727480492 1 1 3.06360818924003 -1.6423063943632 3.15835643055852e-51 352.209735257129 20.6831215910615 17.0288480733654 1.87411777879574e-52 -38.5122932485073 96.4110998611697 -0.399459121449338 0.689711429421455 LSG1 essential 4.78901585565588e-47 1 2.8792071435639e-48 17.0288480733654 -0.399459121449338 4.22616185864579e-20 8.81860171193856 22.8991916733166 0.38510537130507 0.700317119737343 -354.68948429262 41.9296634914494 -8.45915408705701 2.75444127196033e-16 PARP3 other 5.01391842909737e-16 4.17187675051112e-12 1 0.38510537130507 -8.45915408705701 0.503185199567725 -765.31306995506 664.26612387633 -1.15211816837666 0.249780436352579 -845.48032082642 1465.06684602589 -0.57709334090786 0.564116019311464 TNC other 1 1 1 -1.15211816837666 -0.57709334090786 2.14252104365632e-13 129.982233864682 29.9733912427232 4.33658750229802 1.72537072967972e-05 -175.387695780543 49.2353238839041 -3.56223300559785 0.00040004577131223 THAP3 other 2.08081643759902e-09 1 0.152336206101922 4.33658750229802 -3.56223300559785 0.433057334618913 34.0328319304755 30.7003832985326 1.10854746012576 0.268132058709442 -132.789874936984 237.759592663638 -0.558504804997894 0.576737387362311 RIPOR3 other 1 1 1 1.10854746012576 -0.558504804997894 4.76191067806149e-15 99.7423512547477 14.5383948767986 6.86061646419603 1.87459525442984e-11 -49.9129662692401 29.595507768966 -1.68650481211135 0.092273004246841 TDP1 other 4.92238706791217e-11 1 2.20508639778582e-07 6.86061646419603 -1.68650481211135 1.45220646797318e-08 161.627118006723 29.065968036893 5.56069964026561 4.21695208584209e-08 -51.6221434520377 76.9218756059927 -0.671098345501289 0.502442722138983 AIFM2 other 0.000111209971317386 1 0.000439322068303029 5.56069964026561 -0.671098345501289 7.27050390382111e-29 7.46109549365442 5.18139908276217 1.43997699742459 0.150450182565839 -107.96330476465 10.4477873026411 -10.3336047755641 5.67529361019463e-23 SPATA7 other 9.84717048733532e-25 8.8091907417441e-19 1 1.43997699742459 -10.3336047755641 7.09645853614087e-44 222.443736843599 19.4255186644969 11.4511092694863 2.60193145135979e-27 -116.798948663648 42.7450136647915 -2.73245786232731 0.00649382088861345 MED17 essential 1.05559820725095e-39 1 3.77618311535847e-23 11.4511092694863 -2.73245786232731 0.860942452730464 46.2277993170258 127.537140572837 0.362465389371225 0.717145314146056 -167.604792289957 467.225581109824 -0.358723492604658 0.719941382481912 RETSAT other 1 1 1 0.362465389371225 -0.358723492604658 0.350631631855486 38.559723714245 168.806168329119 0.228426034995745 0.819401206530468 -858.395684394055 618.290487296452 -1.38833720076706 0.165604720165807 CAPG other 1 1 1 0.228426034995745 -1.38833720076706 1.47510806604579e-06 301.5108246573 66.3001170153985 4.54766655369963 6.68973184788636e-06 -166.449220418804 190.718665130937 -0.872747406786476 0.383185118119399 AP2S1 essential 0.00969736042618505 1 0.0610772517712025 4.54766655369963 -0.872747406786476 0.0054817834257931 1.76825122456877 0.566694121459527 3.12029216045972 0.0019030758461384 -3.15971009175407 5.27609430800005 -0.598872936551391 0.549508293251227 TG other 1 1 1 3.12029216045972 -0.598872936551391 0.00137442175731909 -41.9039929079719 21.6038503834133 -1.93965391188528 0.0529440923345314 -157.967244872077 43.7205139261268 -3.61311500452601 0.000330912505597092 ADAM28 other 1 1 1 -1.93965391188528 -3.61311500452601 0.00103771951818323 -16.1489342496328 68.8035075261361 -0.234710915624445 0.814521920073807 -437.048991633825 135.143505275938 -3.23396222956813 0.00129534249149861 BARX2 other 1 1 1 -0.234710915624445 -3.23396222956813 2.79349673043133e-33 239.712323837793 18.2878655649719 13.1077256110703 2.76479219476923e-34 -123.90729962838 76.6563919538026 -1.61639879558972 0.106591056082019 DCUN1D1 other 3.93519884415862e-29 1 4.1236875584983e-30 13.1077256110703 -1.61639879558972 5.57237434583003e-19 148.677901026994 56.1840619488361 2.64626472116571 0.00837336120549708 -965.80652238492 129.373045063526 -7.46528399258653 3.30521161340966e-13 JADE2 other 6.4388785566066e-15 4.88113651068339e-09 1 2.64626472116571 -7.46528399258653 9.80018713260737e-07 38.0482294531483 7.14855561525368 5.32250590202592 1.50610230575636e-07 34.473693273433 17.0486814285299 2.02207387227867 0.0436640268110809 ZIC2 other 0.00654358494844194 1 0.00152101271858335 5.32250590202592 2.02207387227867 0.279793065084834 -11.1661132096353 23.2164517110693 -0.480956924365468 0.630740847509351 74.7735280437749 60.2360197350124 1.24134244547889 0.215015241890187 LCP2 other 1 1 1 -0.480956924365468 1.24134244547889 1.07141748857469e-30 176.233928649713 15.4199650336778 11.4289447651023 2.9883268610551e-27 -46.9930445595166 33.9856129325953 -1.38273347174051 0.16731602273751 TRIT1 other 1.47491331477192e-26 1 4.33456811196042e-23 11.4289447651023 -1.38273347174051 0.035866513920076 -10.4797436776188 10.8190368154369 -0.968639247318763 0.333156453193163 -54.2929799735508 20.9855363049282 -2.5871618997319 0.00993579277548773 ADRB1 other 1 1 1 -0.968639247318763 -2.5871618997319 1.49953507843417e-37 350.778886874619 27.7289225809185 12.6502890925883 2.79001965049103e-32 -394.037451822731 134.420727985836 -2.9313741840786 0.00351870224003896 CUL7 other 2.17117684006483e-33 1 4.13425111809761e-28 12.6502890925883 -2.9313741840786 1.17818928084893e-22 900.353623284293 231.505720141023 3.88912041886411 0.000113102851051431 -4308.07777644525 547.69004220519 -7.8659048813439 1.99701870379807e-14 CTNNA1 ts 1.46825948179393e-18 2.98394534721508e-10 0.929479229940664 3.88912041886411 -7.8659048813439 7.7663823221196e-08 56.3210869953902 11.5168963108352 4.89030077855289 1.33221919637242e-06 -29.0396212802545 26.3398347257911 -1.10249823442589 0.270738980591002 CNTLN other 0.000566013943636076 1 0.0127306866405348 4.89030077855289 -1.10249823442589 0.130392061944552 52.4532131027906 35.4441602029154 1.47988308377176 0.139556388153511 -52.5107140385218 74.5604197659737 -0.704270633176954 0.481603663246487 EPHA3 other 1 1 1 1.47988308377176 -0.704270633176954 0.0740018016905325 1456.98110098027 641.195569473105 2.27228816034635 0.0234599753433754 689.511147849251 1468.14921478954 0.469646505207643 0.63879647802208 HSPA5 essential 1 1 1 2.27228816034635 0.469646505207643 4.06475352502376e-13 1217.46016202656 180.845031608215 6.73206308849046 4.26430295225357e-11 -677.390878631423 473.541046786183 -1.43047975086579 0.153154553586408 DSG2 other 3.89728567979279e-09 1 4.96109005465181e-07 6.73206308849046 -1.43047975086579 0.33081957712914 -5.60856678052185 6.79558592144013 -0.825324974970411 0.409554968331718 -87.8979984794863 66.547091611295 -1.32083906826316 0.187119717744968 PREX2 other 1 1 1 -0.825324974970411 -1.32083906826316 3.07027247601956e-09 65.9736421716857 12.3857050026156 5.32659563244512 1.48051338184539e-07 -127.393443440946 49.160756388978 -2.59136459237856 0.00982259368269973 WDR37 other 2.4485422996256e-05 1 0.00149561461834021 5.32659563244512 -2.59136459237856 1.88586498680597e-25 113.427713799021 33.6994870033497 3.36585876775352 0.000816929644490536 -655.393413757445 75.3880304730944 -8.69360042495541 4.14860188886874e-17 YTHDC2 other 2.45332176133588e-21 6.31666123599155e-13 1 3.36585876775352 -8.69360042495541 2.04839003311514e-67 538.087818792369 26.6552670204931 20.1869228463807 2.13898458519236e-66 -445.057047252676 214.109942147919 -2.0786379314661 0.0381703937904559 ATP6V1H essential 3.16537711817282e-63 1 3.31414271629705e-62 20.1869228463807 -2.0786379314661 3.19540702839183e-21 666.561632208478 78.2318006859524 8.5203411702649 1.61173825592477e-16 -410.517762447802 189.426965582562 -2.16715588081824 0.0306618307007628 POLR2B essential 3.87730688825064e-17 1 2.1165346776804e-12 8.5203411702649 -2.16715588081824 1.52615560675774e-26 90.1946212704621 110.364725360572 0.81724138737072 0.414150242523725 -2323.74078861297 225.857667998118 -10.2885184692172 8.53158968556894e-23 FAM214A other 2.01330447643481e-22 1.32384677150973e-18 1 0.81724138737072 -10.2885184692172 0.171212342360093 2.72988392440971 24.4820402378284 0.111505572978825 0.911256879703923 -71.5969756157201 45.8656496067002 -1.56101518739333 0.119106002993654 ARAP2 other 1 1 1 0.111505572978825 -1.56101518739333 1.54171889683993e-11 560.429640229064 79.411936568836 7.05724686292307 5.44309454422626e-12 -558.604223249788 537.694687214242 -1.03888737704268 0.299339007235046 TPR essential 1.38353853802415e-07 1 6.50449798035038e-08 7.05724686292307 -1.03888737704268 0.22900297781489 754.67242584861 467.281131352253 1.61502867377649 0.106885356148024 1272.66645723223 1847.5867708417 0.688826353012066 0.491226752590935 CP other 1 1 1 1.61502867377649 0.688826353012066 1.25632226663208e-17 174.597496984603 23.0670781395896 7.56912062845727 1.62600862612685e-13 -436.842751235381 133.474744948344 -3.27284949227244 0.00113252480198059 KIAA0556 other 1.40406576518802e-13 1 2.01527509122162e-09 7.56912062845727 -3.27284949227244 6.33516485288893e-18 90.898894920682 10.9727587252893 8.28405118497544 9.57977756159265e-16 -59.2951336037375 36.2704575281699 -1.63480522840621 0.102677000774696 DTNBP1 other 7.13846375623525e-14 1 1.24048539645063e-11 8.28405118497544 -1.63480522840621 0.586576243041238 11.6008101623222 30.5837360428226 0.379313048807347 0.704603697691127 -88.1371473976566 107.769674673583 -0.817828834174455 0.413813645874933 ANO2 other 1 1 1 0.379313048807347 -0.817828834174455 1.11697714340699e-45 147.929137894668 9.77064175892427 15.1401659731873 1.87054140116227e-43 -18.9380449545828 35.0085319168901 -0.540955130581926 0.588760351758874 C12orf4 other 1.67122120196554e-41 1 2.843784092187e-39 15.1401659731873 -0.540955130581926 4.16502571121241e-11 -12.5733787877431 22.2583074500641 -0.564884765652154 0.572385006355309 -274.027651404418 42.5910873190068 -6.43392006764124 2.7290037913197e-10 FAM184B other 3.66522262586692e-07 3.8702731768496e-06 1 -0.564884765652154 -6.43392006764124 1.56166616351395e-06 654.122658580107 198.363505999371 3.29759577138237 0.00104198120483866 -698.454575518203 364.335320278644 -1.91706523261051 0.0557783534141965 MAP4 other 0.010239845034161 1 1 3.29759577138237 -1.91706523261051 6.15038061058291e-35 201.266795245721 20.3833660247219 9.87407060254991 2.99309750886096e-21 -303.546096535742 64.4366469792639 -4.71076802977388 3.14267393977512e-06 GOPC other 8.76921267456912e-31 0.03899115557079 4.16130346656939e-17 9.87407060254991 -4.71076802977388 0.485159724266517 37.3402730595769 38.8375716056291 0.961447163554501 0.336757688692593 -36.3754121212732 122.774760952071 -0.2962776049344 0.767131996086549 ROS1 og 1 1 1 0.961447163554501 -0.2962776049344 7.98799017624054e-35 141.598583871479 21.7000747971528 6.52525787100316 1.55136392194104e-10 -243.641806947411 40.0423046838241 -6.08460998614385 2.19921370904946e-09 USP28 other 1.13796908050723e-30 3.05712697694966e-05 1.77631169062249e-06 6.52525787100316 -6.08460998614385 0.83865969196368 19.1045903024866 32.7566573656117 0.583227711217654 0.559983058559164 33.9110659841862 139.93265228114 0.242338478056252 0.808609740992767 HDAC9 other 1 1 1 0.583227711217654 0.242338478056252 3.86490111991383e-20 215.543590550514 25.8942089303063 8.32400754665436 7.05867150882214e-16 -153.750444803658 73.6738448026113 -2.08690676067727 0.0373666989950862 TSPAN17 other 4.58725113922572e-16 1 9.16921428995997e-12 8.32400754665436 -2.08690676067727 1.25849366756785e-09 132.792647111306 21.4478112556576 6.19143116882274 1.17829119885296e-09 12.337119830761 60.104909106338 0.205259770195044 0.83744623815654 NOP16 essential 1.02441384540023e-05 1 1.30813888896655e-05 6.19143116882274 0.205259770195044 0.000101605249588103 11.8283983806073 17.0240758067645 0.694804141785323 0.487475788872757 -109.959350158662 32.4898622149594 -3.38442032875206 0.000764906287026103 CC2D2A other 0.551716505263397 1 1 0.694804141785323 -3.38442032875206 5.18605487658964e-28 228.309187123468 19.6267345822944 11.6325609930767 5.03909689261113e-28 -608.759120606104 267.665959092319 -2.27432402189081 0.0233438593324962 RRM2B other 6.95864843340798e-24 1 7.34146026284515e-24 11.6325609930767 -2.27432402189081 4.74121915270336e-15 66.8302366489756 15.881744417422 4.20799094183029 3.01372867586515e-05 -265.393018446958 48.9879268163923 -5.41751888055308 9.08857266263842e-08 ZNF800 other 4.90147236006473e-11 0.00120478119215935 0.261531374491578 4.20799094183029 -5.41751888055308 0.108298318154648 -0.361766907285189 2.05204339591354 -0.176295934094579 0.86012718612276 20.9084623314597 10.6668207351894 1.96014003146068 0.0504903986052792 TNFRSF17 other 1 1 1 -0.176295934094579 1.96014003146068 6.38054049585635e-10 82.924288233254 16.2931296784673 5.08952484081956 4.95803180966543e-07 -223.046317532276 86.248971524487 -2.58607509851814 0.00996726667624282 SNX29 other 5.27925920627155e-06 1 0.00486432500846276 5.08952484081956 -2.58607509851814 0.00183217758088392 96.7964276535904 29.2578212093132 3.30839494031697 0.0010014351127065 -19.2830165944553 92.8287676334823 -0.207726732628734 0.835521391293338 LMO3 other 1 1 1 3.30839494031697 -0.207726732628734 4.22398835533553e-76 360.236392336128 16.9848977111694 21.2092176509979 3.8431182535298e-73 -46.0040384382525 81.277713640864 -0.566010488945681 0.571620911777415 MRPS10 essential 6.55562992748075e-72 1 5.97412732511207e-69 21.2092176509979 -0.566010488945681 3.53693346467707e-72 553.344760145675 27.1230751933472 20.401254511192 6.3378680326084e-68 -320.526816261381 164.326068489617 -1.95055367177871 0.0516629367794458 RSF1 other 5.48047840351712e-68 1 9.82813195816584e-64 20.401254511192 -1.95055367177871 5.88116350638849e-10 152.13355845295 93.3941588873304 1.62894082740744 0.103903397128791 -680.600262614809 147.600642095561 -4.61109283097947 4.99594786410529e-06 VPS13D essential 4.87666077949734e-06 0.061400199249854 1 1.62894082740744 -4.61109283097947 0.417398822012074 -42.2065586525321 34.1039701064406 -1.23758490641421 0.216405875105269 41.2707111978307 147.812734924196 0.27920944172365 0.780190605143598 CELF2 other 1 1 1 -1.23758490641421 0.27920944172365 1.75623206562749e-15 386.413402258791 159.168704187512 2.42769710434766 0.0155202344256118 -2360.00827472004 344.719337438663 -6.84617315714111 2.06441762702214e-11 FAM120A other 1.84176056722355e-11 2.9839092380978e-07 1 2.42769710434766 -6.84617315714111 2.18032991961376e-08 197.617549844891 35.1447573100929 5.62295958117597 3.00912630417324e-08 -14.6178244662064 79.9205151124062 -0.182904532655312 0.854941322107944 R3HDM1 other 0.000165334417804311 1 0.000315717531833857 5.62295958117597 -0.182904532655312 0.0253045051319942 200.936099341155 79.4241836167181 2.52991079279862 0.0116923584523724 -27.4016934105603 172.602426232246 -0.158756131120022 0.87392036687133 COL9A2 other 1 1 1 2.52991079279862 -0.158756131120022 0.00606680728803134 -20.9027981862524 150.877010510664 -0.138541969485635 0.889864824371578 -1198.46249995469 383.384322571759 -3.12600810569235 0.00186931240582747 KITLG other 1 1 1 -0.138541969485635 -3.12600810569235 8.12244170960378e-11 19.2305489084688 4.16416389593777 4.61810567236045 4.84791578167934e-06 -27.0682231000292 9.53692528752064 -2.83825470830193 0.0047070736299977 ERCC8 other 7.04134471805551e-07 1 0.0446444564334851 4.61810567236045 -2.83825470830193 0.000227158049694185 -7.70148291101065 4.4626060720762 -1.72578147984 0.0849587784931431 -40.6528649948842 9.84728270823143 -4.12833328740548 4.23238264904499e-05 ADAMTS6 other 1 0.490448501371334 1 -1.72578147984 -4.12833328740548 3.30268218633179e-08 -48.1878634317693 97.1829412424514 -0.495846933790062 0.620204522626293 -866.095176244896 159.715818676685 -5.42272633619431 8.8733550531481e-08 H6PD other 0.000247436949399978 0.00117660688004744 1 -0.495846933790062 -5.42272633619431 2.28953871940945e-15 188.656947952426 56.0350496742919 3.36676685483478 0.000814502209470372 -471.87744262438 91.9812263644686 -5.13014950197121 4.03858695785462e-07 VAMP3 other 2.39142319242317e-11 0.00521179646911139 1 3.36676685483478 -5.13014950197121 0.000212363912804289 -6.65808274264279 56.623946789572 -0.117584222226434 0.906440747726459 -340.739439979993 93.0006046811091 -3.66384112391913 0.000272918625060383 PER3 other 1 1 1 -0.117584222226434 -3.66384112391913 0.00010295769733984 0.584176341035528 9.31078752424954 0.0627418829517982 0.949995218765181 -56.9185859867857 15.2752223174578 -3.72620344266509 0.000214823248976463 UTS2 other 0.558442550371294 1 1 0.0627418829517982 -3.72620344266509 0.791232967847576 3.40016547713738 8.57375089957845 0.396578524027862 0.691834672385271 9.57875088689972 14.066044439793 0.680983977258121 0.496172991981421 TNFRSF9 other 1 1 1 0.396578524027862 0.680983977258121 6.17818935716441e-89 662.983705339525 27.6369958339044 23.9889932076551 2.53516991829719e-86 -208.408217838097 134.225857481516 -1.55266817995032 0.121107319129453 EPN3 other 9.63056156994789e-85 1 3.95258341961715e-82 23.9889932076551 -1.55266817995032 0.0134970518356377 294.079382943705 109.21656045064 2.69262629889002 0.00730688852943038 602.043035342641 338.395135804306 1.7791125570162 0.0757775419724133 LTBP1 other 1 1 1 2.69262629889002 1.7791125570162 0.0853172822278628 -403.082881595383 284.770178610551 -1.41546732021626 0.157513364495693 1414.39039718253 1050.13938291857 1.34685968376086 0.178595669714882 ELN other 1 1 1 -1.41546732021626 1.34685968376086 4.58188044408428e-12 171.208014426152 27.1971113010446 6.29508084630944 6.41473367176518e-10 -237.050316295007 100.285574355241 -2.36375289087248 0.01844796449427 RFC2 essential 4.21807913682399e-08 1 7.1928408661503e-06 6.29508084630944 -2.36375289087248 1.05876752407541e-23 171.933524928994 51.7993852155961 3.31921941184018 0.000963017555257933 -805.675383021304 109.737088233856 -7.34186951729908 7.71117620049522e-13 ARID1B other 1.34156432975596e-19 1.13392846028282e-08 1 3.31921941184018 -7.34186951729908 5.13093688110016e-33 754.293193893595 57.7548806443932 13.0602502416706 6.02074805196493e-34 199.029743906116 264.761453127718 0.751732329441878 0.45254954771575 CLPTM1L other 7.21666272326737e-29 1 8.97091459742775e-30 13.0602502416706 0.751732329441878 2.07213972324998e-13 331.555518897593 112.137064939367 2.95669874253322 0.0032455021266146 -1243.56681683257 234.316856804099 -5.30720168319882 1.62792761035073e-07 NEDD4L other 2.01432702497131e-09 0.00213421309716981 1 2.95669874253322 -5.30720168319882 4.45527551471897e-16 353.788726826964 66.3662455520217 5.33085341628439 1.43290209094062e-07 -658.495344875048 154.757920851476 -4.25500253073973 2.46017793293384e-05 HEXB other 4.76046188747722e-12 0.289562942706313 0.00144938046498643 5.33085341628439 -4.25500253073973 8.53728089061554e-35 53.0546969501323 7.19416294153349 7.37468658707128 6.18043185948818e-13 -128.238875095209 16.9956406751313 -7.54539811393243 1.90802952747165e-13 PTCD2 other 1.21579417163256e-30 2.82445610951629e-09 7.54507121406317e-09 7.37468658707128 -7.54539811393243 1.4594629451069e-35 146.416842045274 27.949551119352 5.23861157626596 2.31697739536648e-07 -588.738220712742 59.9157140906211 -9.82610705135366 4.37019871079382e-21 JKAMP other 2.09082661516014e-31 6.75283104791861e-17 0.00231767248858509 5.23861157626596 -9.82610705135366 0.109195230552358 -176.772106312043 84.4515560719432 -2.0931776101491 0.0368018765088696 -192.483279506807 182.206672332064 -1.05640082793463 0.29126014024457 DKK3 other 1 1 1 -2.0931776101491 -1.05640082793463 0.0026221753218996 93.7607535899059 34.1763542554444 2.74343930569978 0.00628351156843232 442.802840045474 176.342932279846 2.51103253371545 0.0123309810792461 NFE2L3 other 1 1 1 2.74343930569978 2.51103253371545 6.41665649225513e-14 224.969822252528 30.1047435776199 7.47290278930569 3.20506780152659e-13 -76.1638969158446 103.055170562146 -0.739059442630437 0.460193816036651 MCUR1 other 6.35954824947405e-10 1 3.94607947723953e-09 7.47290278930569 -0.739059442630437 5.71702565869338e-16 197.241549576077 103.762542585532 1.90089356584039 0.0578451648753041 -2322.8714495313 305.029530051344 -7.61523465987148 1.17562392221586e-13 LIMA1 other 6.09034743420606e-12 1.74427321339167e-09 1 1.90089356584039 -7.61523465987148 7.57956483610628e-10 38.1348194347333 26.1725439379754 1.4570543667863 0.145681536271257 -446.448944352965 77.258375501544 -5.77864783532813 1.27245269835202e-08 LETMD1 other 6.24480346846796e-06 0.000173448027312364 1 1.4570543667863 -5.77864783532813 4.84420253440443e-06 40.4401030158353 55.3474745304858 0.730658505358913 0.465303483658299 -738.990656260766 163.077596211555 -4.5315277722275 7.2097160172713e-06 SLC4A8 other 0.0302869571776474 0.0877927119423127 1 0.730658505358913 -4.5315277722275 0.0706141399562334 -10.3713400629151 10.9008201432112 -0.951427500560509 0.341812263446205 -58.1112871779016 25.236789246603 -2.30264185392457 0.0216776317185065 LAMC3 other 1 1 1 -0.951427500560509 -2.30264185392457 0.00154224425715615 -161.854192297203 117.624118416234 -1.37602895117524 0.169383061254128 -831.421444804701 229.758695939898 -3.61867237017306 0.000323947673508226 PTGER3 other 1 1 1 -1.37602895117524 -3.61867237017306 0.00314876917834603 7.56813680391662 4.80382566837318 1.57543951974418 0.115738512562285 39.2842157896793 11.5722763162379 3.39468352778239 0.000737380300696181 TNIP3 other 1 1 1 1.57543951974418 3.39468352778239 6.64010524569955e-31 247.363040536237 35.7867186246235 6.91214646223631 1.37116517170366e-11 -735.900988258075 96.7816150003507 -7.60372709481453 1.31125473537792e-13 MAPK9 other 9.16068919696711e-27 1.94445964709191e-09 1.62016876688504e-07 6.91214646223631 -7.60372709481453 0.296622923586001 -2.26235057588096 4.50849694858654 -0.501797073765399 0.616014419036994 14.7719488864508 12.1953978986449 1.21127240039394 0.226319851833422 COL23A1 other 1 1 1 -0.501797073765399 1.21127240039394 9.9351845932337e-18 211.342698288232 49.4130483438603 4.27706254464448 2.23582436253563e-05 -430.100937667835 108.339019888795 -3.96995411357158 8.15003706976043e-05 BCAR1 other 1.11363484105557e-13 0.924784706305717 0.195880572401746 4.27706254464448 -3.96995411357158 3.68201894101421e-21 51.4394006411699 19.2655590836643 2.67001857655855 0.00781023397233872 -343.655381097357 43.5361996141935 -7.89355488404459 1.61366105424075e-14 FAM160A2 other 4.46334336029743e-17 2.41290737440619e-10 1 2.67001857655855 -7.89355488404459 4.95270910897383e-19 359.375886657142 91.9021499298237 3.91041871089589 0.000103784425151293 -866.287100538937 195.578777398254 -4.42935124180131 1.14310458285068e-05 HERPUD1 other 5.73077970999362e-15 0.137515481316937 0.856221507498167 3.91041871089589 -4.42935124180131 1.42807839429152e-06 229.373995732771 46.8125590688844 4.8998388529721 1.27374533642723e-06 -63.1914965643272 155.128318194853 -0.407349846241185 0.683914299260641 HOMER3 other 0.00940246814801539 1 0.0121859216335993 4.8998388529721 -0.407349846241185 1.17639088709439e-07 85.6323621707448 15.5805111740092 5.49612019877714 5.97474535654941e-08 109.854127398892 27.3424144684898 4.0177186080436 6.70393298426042e-05 RAD51 essential 0.000846530882353123 0.765388028813012 0.000618266649495733 5.49612019877714 4.0177186080436 1.99299642588183e-13 83.7593682540962 10.671320641055 7.84901616880062 2.24738621002328e-14 38.1047104451233 35.0061561641131 1.08851455345408 0.276850895025693 POLQ other 1.93858762345526e-09 1 2.8384487832594e-10 7.84901616880062 1.08851455345408 3.54783923087447e-12 218.588825844671 32.5566569890124 6.7141053799978 4.7553074403844e-11 -309.953959685674 120.030815366024 -2.58228654650471 0.0100740629080135 PIK3CB other 3.28210607248197e-08 1 5.52376512275052e-07 6.7141053799978 -2.58228654650471 5.88864957802272e-07 249.256108677558 94.0170810310017 2.65117897667304 0.00825931529011706 -407.643356843581 202.163760529773 -2.01640173182051 0.0442581255534091 CYBA other 0.00400964876181746 1 1 2.65117897667304 -2.01640173182051 4.03570632767571e-09 119.458298154075 19.9433208262199 5.98989000853963 3.83201845085958e-09 13.1810047277968 55.4018653783596 0.237916262165161 0.812036121114193 THOC3 essential 3.19870083531577e-05 1 4.16578725792945e-05 5.98989000853963 0.237916262165161 7.35739760456672e-16 516.860470118906 76.9687714729023 6.71519708874231 4.88199678102075e-11 -296.679364952731 173.98735445205 -1.70517774632003 0.0887517063881118 HEBP2 other 7.81134903676849e-12 1 5.6699510614775e-07 6.71519708874231 -1.70517774632003 1.97017925331252e-13 108.409838927441 14.9304200081914 7.26100396827166 1.33900769093108e-12 -26.3026590683296 33.7749915861309 -0.778761380332373 0.43645952508154 MPHOSPH9 other 1.91678739554775e-09 1 1.62327902371574e-08 7.26100396827166 -0.778761380332373 5.01419829853873e-16 139.756033940477 22.5775055489235 6.19005645409487 1.20705674749628e-09 -307.113982669248 76.7057228255246 -4.00379491068498 7.12483773544266e-05 PLEKHA5 other 5.34764248539156e-12 0.812160253463109 1.33971228404612e-05 6.19005645409487 -4.00379491068498 8.82338605980377e-17 1454.71194357658 177.392758606529 8.20051480682612 1.91995968760705e-15 -1477.3947456582 1045.90876678248 -1.41254647879385 0.158393123962713 PRSS8 other 9.62543185263993e-13 1 2.47463604135673e-11 8.20051480682612 -1.41254647879385 3.56885589286114e-14 195.056155596291 28.1548848469797 6.92796850906727 1.22382706976558e-11 -70.231093844025 65.4816966907723 -1.07253014801496 0.283962831908406 SIKE1 other 3.57242474875401e-10 1 1.44901125060245e-07 6.92796850906727 -1.07253014801496 8.7780371027835e-13 218.093123839944 39.2284616288786 5.55956351037207 4.23290911471505e-08 -194.053049596409 76.1446599402101 -2.54847877380742 0.0110915126317578 RRP12 essential 8.30928992149487e-09 1 0.00044089981338872 5.55956351037207 -2.54847877380742 0.000250467910270944 101.261454655171 30.3432033893096 3.33720383296271 0.00090430918555875 -63.7256450176198 67.7146721793727 -0.941090652389393 0.347077647552478 FNIP2 other 1 1 1 3.33720383296271 -0.941090652389393 1.04915319283767e-08 351.346526245939 77.9378401410859 4.50803519330173 8.02920701078849e-06 -383.122953475233 171.020677007639 -2.24021422543029 0.0254829655493308 MSMO1 other 8.09841349551398e-05 1 0.0728650536229055 4.50803519330173 -2.24021422543029 1.57485733754361e-11 172.292089379051 63.3627027686719 2.7191404698765 0.00676020213338084 -880.723472215675 166.174831993115 -5.29998112019856 1.70321515953871e-07 TTC17 other 1.4120170888416e-07 0.0022305305729319 1 2.7191404698765 -5.29998112019856 0.719232098405493 -12.9458191872879 19.1762851067813 -0.675095260380221 0.49990853984032 -33.3367610514157 50.4538875757541 -0.660737212793805 0.509066861061732 ALX4 other 1 1 1 -0.675095260380221 -0.660737212793805 0.000949317520251135 24.8275849793164 14.0641991326809 1.76530385733978 0.078072659238621 -77.2093691609935 32.361787540011 -2.38581904863984 0.0173816277411764 FSTL4 other 1 1 1 1.76530385733978 -2.38581904863984 0.0036016091873638 97.4977327644342 63.4771275076484 1.5359506107564 0.125132947952821 -270.797144227851 128.109879785806 -2.11378813781273 0.0349887354161939 FOXN3 other 1 1 1 1.5359506107564 -2.11378813781273 1.01006235710533e-14 129.435080179852 60.4106225842586 2.14258808538715 0.0325876825096637 -579.443017187306 100.897338904501 -5.74289692353278 1.5465117978799e-08 AKR7A2 other 1.03127366660455e-10 0.000210217348685815 1 2.14258808538715 -5.74289692353278 1.31393337018868e-19 361.409587665991 41.8669136425412 8.63234368675221 6.59986961893347e-17 43.5326795840649 69.7189037767477 0.624402812233885 0.532623891383913 MRTO4 essential 1.5438717099717e-15 1 8.7296475449633e-13 8.63234368675221 0.624402812233885 0.481515237187776 -3.05770344508744 7.82667628129047 -0.390677132309257 0.696192003560512 -62.852911644583 52.9442281310979 -1.18715323394554 0.235695999499583 NNAT other 1 1 1 -0.390677132309257 -1.18715323394554 2.29805697417848e-19 106.845532802502 12.057446722668 8.86137299712323 1.11864314866195e-17 -59.4808497147888 43.5640513163956 -1.36536543130007 0.172701508945968 USE1 other 2.68619879711723e-15 1 1.49696826153943e-13 8.86137299712323 -1.36536543130007 1.96865771649353e-13 62.8050550732365 9.14241529698501 6.86963488674031 1.77186295149559e-11 136.030594087587 38.8939465291992 3.49747470304829 0.0005082355092266 MCF2L2 other 1.9155039581482e-09 1 2.08636862538605e-07 6.86963488674031 3.49747470304829 0.00142954826972283 -1.92589082195468 2.44105962697466 -0.788956894240863 0.430485376927715 -39.1424603912738 10.7502490001144 -3.64107476867349 0.000297787907455796 NRIP2 other 1 1 1 -0.788956894240863 -3.64107476867349 0.00647154743059313 153.468359138262 144.061685564172 1.06529615100123 0.287230685319015 -786.211967752506 329.532141528572 -2.3858430443403 0.017392847037195 LAMA3 other 1 1 1 1.06529615100123 -2.3858430443403 1.06358863857304e-26 147.773608172583 25.3346030139664 5.83287640588324 9.37350914331773e-09 -402.707717277118 55.1608930648597 -7.30060183767516 1.02706976234813e-12 AP5M1 other 1.40617053905742e-22 1.50886818786564e-08 0.000100418403452363 5.83287640588324 -7.30060183767516 1.27576899160646e-22 56.0447227719852 13.1195620958077 4.27184401146241 2.29048505123591e-05 -145.694188628689 23.779222604827 -6.12695339330035 1.72576463887685e-09 ANAPC4 essential 1.58897027904585e-18 2.40502560073878e-05 0.200554871086216 4.27184401146241 -6.12695339330035 0.026839516600094 -7.89301383704864 16.4583104650047 -0.479576190632175 0.631721168728189 -84.5256586572498 32.9002106344827 -2.56915250775502 0.0104596648494762 KCNQ1 other 1 1 1 -0.479576190632175 -2.56915250775502 9.498094814074e-22 245.466660645845 35.0091596814918 7.01149821586879 7.08604614527704e-12 -303.571178599854 69.4968323647564 -4.3681297157049 1.50337183662084e-05 TRAPPC3 essential 1.16446642420547e-17 0.179577765884359 8.44018956363948e-08 7.01149821586879 -4.3681297157049 1.72748013814088e-07 105.02105212879 93.6208704437331 1.12176966130547 0.262458951656112 -886.123189394059 186.956222578089 -4.73973627181057 2.74064659590234e-06 THRAP3 other 0.00122875662225961 0.03412379076558 1 1.12176966130547 -4.73973627181057 4.09471257809129e-05 76.0823728426524 67.8611344029123 1.12114796653602 0.262753544283384 -598.87358362719 157.579831249785 -3.80044564635873 0.000161916266935127 PHPT1 other 0.234299453718384 1 1 1.12114796653602 -3.80044564635873 6.60993723374864e-06 141.087635172344 29.997204147015 4.7033595024683 3.3025239651527e-06 206.12453856968 69.6635891582569 2.95885614077994 0.00323186334927423 ENTPD2 other 0.0407899226694629 1 0.0307431955916065 4.7033595024683 2.95885614077994 0.186673236461951 85.0321708844414 47.4542508085115 1.79187679577042 0.0737053012209605 110.34301951667 119.138820565576 0.92617183041472 0.354765127594638 LY75 other 1 1 1 1.79187679577042 0.92617183041472 1.47775425103743e-33 504.301017591238 38.3037437322772 13.1658414675086 1.51741418256024e-34 -83.4868202294045 243.821032519136 -0.342410248069359 0.732174918660183 ARID4B other 2.08540679906403e-29 1 2.26474066747115e-30 13.1658414675086 -0.342410248069359 2.01529966492586e-06 118.400910997477 23.118284611201 5.12152666120006 4.21878234816389e-07 -58.1727137067601 142.166704293452 -0.409186623519692 0.682564354848186 OPN3 other 0.013101463121683 1 0.00416014127352442 5.12152666120006 -0.409186623519692 1.10866094573687e-22 109.385959084971 10.4068025522337 10.5110055212388 1.19906082745379e-23 -14.8431107694872 65.2469176825251 -0.227491371189517 0.820127306334693 SDCCAG8 other 1.38250019933388e-18 1 1.7021867506534e-19 10.5110055212388 -0.227491371189517 0.669411239059544 -4.417596446084 16.6733684407675 -0.264949248964155 0.791149848828269 -33.5443141888103 37.4470273872539 -0.895780427159566 0.370769916354704 PTPRN other 1 1 1 -0.264949248964155 -0.895780427159566 8.40008410327948e-10 77.5950808048129 12.6467489179825 6.13557534098584 1.65607956435965e-09 -165.696805199695 83.5568394123154 -1.98304299642135 0.047875462212147 HHAT other 6.90066909084409e-06 1 1.82582771970651e-05 6.13557534098584 -1.98304299642135 7.77145664144726e-05 383.725039782989 105.444476442595 3.63911939941106 0.000299751508187427 -49.7379654746891 173.352996752933 -0.286917252117521 0.774285330930133 KIF1B other 0.428751262908645 1 1 3.63911939941106 -0.286917252117521 6.45893852243666e-08 566.089997619088 97.199158744596 5.8240215751925 1.01348963766992e-08 686.659043856569 287.413838571196 2.38909527554455 0.0172495521677392 FOXC1 other 0.000473763140620729 1 0.000108443391230681 5.8240215751925 2.38909527554455 2.56454666279921e-35 88.1756822255231 16.2964135407641 5.4107415723686 9.4693697517677e-08 -246.74267753685 30.496409432647 -8.09087634010799 3.97440362236347e-15 TBC1D22A other 3.668327546468e-31 5.97233632332559e-11 0.000969000606698388 5.4107415723686 -8.09087634010799 0.000248118402425003 140.731737349181 131.643854028255 1.06903385948405 0.28553116245923 -849.934092001387 266.325490246391 -3.19133587706933 0.00149835360681255 SYNE2 other 1 1 1 1.06903385948405 -3.19133587706933 1.54566978146251e-09 29.7905574686598 21.9334542379036 1.35822461640257 0.174963824972314 -214.009051042176 42.2293456910305 -5.06778041525828 5.54934928456974e-07 PLEKHH1 other 1.2532290588098e-05 0.00712702928617291 1 1.35822461640257 -5.06778041525828 4.37743893317629e-17 681.424717218829 78.1553558608306 8.7188486280099 3.68949731453606e-17 -749.266135332793 603.258753458789 -1.24203110362986 0.214778576835682 ATP9A other 4.82262447268032e-13 1 4.89965243370389e-13 8.7188486280099 -1.24203110362986 0.0320302327996429 -1.11635506996239 1.24973931236971 -0.893270347594011 0.3721209131578 -24.7071693806714 9.65879238579179 -2.55799776968143 0.0108067874521249 CBLN4 other 1 1 1 -0.893270347594011 -2.55799776968143 0.817372252336323 -7.40259975403885 14.7631091191665 -0.501425525902826 0.616281866871382 -32.8413942472639 63.5158679847731 -0.517058103577158 0.605333356027402 CHRDL2 other 1 1 1 -0.501425525902826 -0.517058103577158 7.5042404424688e-37 660.006601865733 51.8799620037948 12.7218019515407 2.07044131636486e-32 -242.439161775309 181.895127123196 -1.33285132817828 0.183173399249429 FAM168A other 1.0818113021863e-32 1 3.07005038390582e-28 12.7218019515407 -1.33285132817828 3.03278174785449e-17 50.5965616527197 5.94086491063207 8.51669957385658 1.91159083524948e-16 -0.849660576217121 20.9012443812824 -0.0406511957239261 0.967590099611101 RELT other 3.35577300400099e-13 1 2.50724253951322e-12 8.51669957385658 -0.0406511957239261 5.86592875755799e-22 64.4682538095789 33.7450647446207 1.91044984792497 0.056602702723349 -574.379539911422 67.9517987503491 -8.45274960301874 2.64009917254655e-16 GALC other 7.22271807918115e-18 3.99895821665627e-12 1 1.91044984792497 -8.45274960301874 4.09654943060447e-11 411.836303105522 58.3162724513471 7.06211638353797 5.04158702949974e-12 226.612087302012 142.157813082133 1.59408816433526 0.111498159372734 NOP58 essential 3.60578280881805e-07 1 6.02923392857874e-08 7.06211638353797 1.59408816433526 2.63727336148154e-31 355.273652812392 75.3281053517741 4.71634924512309 3.05441128641138e-06 -863.317916467217 116.378072244649 -7.41821805273036 4.57841208718047e-13 SZRD1 other 3.65394224233267e-27 6.7508686225476e-09 0.0285190381812231 4.71634924512309 -7.41821805273036 0.00869550354951648 48.8935249331637 17.2978664935315 2.82656389742905 0.0048780999977124 -12.637935452435 53.6156811418442 -0.23571341785252 0.813743768748275 KCNH2 other 1 1 1 2.82656389742905 -0.23571341785252 4.81560224881508e-24 273.836648131942 33.9483897387688 8.06626323778835 4.78897389462239e-15 -461.368422835864 106.215761353847 -4.34369077578668 1.67663896535775e-05 CUL1 essential 6.13315102409089e-20 0.199805065501683 6.12797099555882e-11 8.06626323778835 -4.34369077578668 7.44934076450737e-32 68.8974353664102 15.5566088798428 4.42882095311162 1.14581996803643e-05 -352.0997199292 35.890102483543 -9.81049636430129 4.98446706217356e-21 FAM114A2 other 1.03672475419649e-27 7.70150005776437e-17 0.102791509332548 4.42882095311162 -9.81049636430129 0.000142369877138173 189.567814262174 83.4834689865879 2.27072277378207 0.0235524194188038 -493.060055673121 190.637184988943 -2.58637922974847 0.00995667281753664 CYFIP2 other 0.757834856006495 1 1 2.27072277378207 -2.58637922974847 4.71336466387335e-21 383.903439249891 57.2738377861599 6.70294595384457 5.10333399388824e-11 -565.479950393283 142.001059343421 -3.98222346373983 7.75172641234204e-05 TAB2 other 5.70175723388759e-17 0.880751154970303 5.92395010010546e-07 6.70294595384457 -3.98222346373983 1.88013459074728e-27 100.639194477241 21.4525425866479 4.69124785888453 3.43762969561251e-06 -416.53777755642 53.5758871344277 -7.77472478451511 3.79697939266433e-14 GINM1 other 2.50847557097503e-23 5.65673989919132e-10 0.031973393798892 4.69124785888453 -7.77472478451511 9.70030083191721e-07 436.160026991906 96.9329979219449 4.49960319336376 8.33621302764273e-06 -587.427590988937 308.246833601316 -1.90570519127769 0.0572172486320201 EIF2AK2 other 0.00648368107605346 1 0.0756177883737472 4.49960319336376 -1.90570519127769 2.69638977414667e-26 318.896425536677 28.2356532894014 11.2941047358865 1.05069432934231e-26 7.83542649456578 80.5039637179195 0.0973296982248053 0.922500618810121 USP36 essential 3.54575255300287e-22 1 1.51972427796072e-22 11.2941047358865 0.0973296982248053 9.06291525405564e-06 177.816077399556 86.7154282903589 2.05057024920819 0.0407900718980809 -836.777777887393 246.704491523085 -3.39182222715671 0.000745055797706965 KMT2C other 0.0553381605412638 1 1 2.05057024920819 -3.39182222715671 0.0564374063795422 31.1948991459893 15.8062149328814 1.97358439566041 0.0489365068102173 -12.3106819688019 29.9923741927642 -0.410460402023522 0.68163045356922 MCOLN3 other 1 1 1 1.97358439566041 -0.410460402023522 0.33538425302119 -17.2539733846963 11.7612168215175 -1.46702281290568 0.142949836210349 -16.1247466807568 42.2020826552805 -0.382084145288959 0.7025487150437 CCDC85A other 1 1 1 -1.46702281290568 -0.382084145288959 3.19786474741914e-13 453.317655249671 86.6569122874725 5.23117710155482 2.40901116790991e-07 -1090.51369672985 250.775279935272 -4.34856935265438 1.63677003490547e-05 PUM2 other 3.08338118946154e-09 0.195233929763524 0.00240780666232596 5.23117710155482 -4.34856935265438 1.15590296524731e-29 175.150375605214 33.9527926032751 5.15864416962036 3.48612695704065e-07 -534.367027247923 65.4922878056091 -8.15923592154858 2.33492825320172e-15 MRPL43 essential 1.57711400578343e-25 3.51710242779775e-11 0.00345405458903588 5.15864416962036 -8.15923592154858 0.404763833925287 -37.8398668632059 69.6853506820722 -0.543010352862311 0.587349248568734 -170.830724020627 127.380078113299 -1.3411102155918 0.180454804251632 ITIH4 other 1 1 1 -0.543010352862311 -1.3411102155918 4.4231040867848e-12 59.0961049730422 9.59795978245655 6.15715280252163 1.44814049034188e-09 -22.9480551702508 20.1871603004593 -1.13676489554247 0.256141709344832 HPF1 other 4.07456348474615e-08 1 1.60106412612198e-05 6.15715280252163 -1.13676489554247 0.000305174363112977 223.363337841046 55.4376303270404 4.02909245080228 6.40760112506603e-05 123.826895809776 251.628101457279 0.492102810030534 0.622847774656641 ZFR other 1 1 0.539135558663056 4.02909245080228 0.492102810030534 0.0116828267922318 6.10213431600232 3.39445653708199 1.79767637303377 0.0727868225194405 -14.036946546437 8.91078442781975 -1.5752761903445 0.115778355232627 NPFFR2 other 1 1 1 1.79767637303377 -1.5752761903445 0.29978179235383 -1.92181156643156 7.20769259883001 -0.266633397592944 0.789852105531626 -21.0260362552088 14.3464047172932 -1.46559620124643 0.143333944958055 PHF21B other 1 1 1 -0.266633397592944 -1.46559620124643 0.4956710429492 12.217630692135 15.6018424752698 0.78308896603084 0.433918800646262 41.0906950914876 37.8659531918897 1.08516204209244 0.278335002994161 TRAF1 other 1 1 1 0.78308896603084 1.08516204209244 1.33211116582811e-07 259.824876501658 48.1963604150342 5.39096467584321 1.04903088929613e-07 -42.3111974821253 119.563221766542 -0.353881376371252 0.723565912358338 RC3H2 other 0.000955390128131922 1 0.00106948699163741 5.39096467584321 -0.353881376371252 5.25723145256495e-05 -37.5357830489511 51.3853003813791 -0.730477058037267 0.465417788959484 -397.780176047083 94.3174849943534 -4.21745953118764 2.90050266144055e-05 IL17RB other 0.296139847722984 0.339735876734532 1 -0.730477058037267 -4.21745953118764 9.32543795983457e-26 149.358628964218 20.4921923895397 7.28856269378274 1.12160672299538e-12 -273.500712236843 58.6686737770625 -4.66178446910406 3.95639289451709e-06 TRAF3IP2 other 1.217529180036e-21 0.048837713889919 1.36163056171639e-08 7.28856269378274 -4.66178446910406 0.0005653578264166 129.129490680175 35.1924427637785 3.66923920419303 0.000267266650512456 -92.3791424699797 121.93415966595 -0.757614951569445 0.449010172895415 DCBLD2 other 1 1 1 3.66923920419303 -0.757614951569445 0.486633019325361 -14.4973612087934 29.5935055412463 -0.489883200507879 0.624414774721141 51.4651335786286 64.6468726271099 0.796096260920231 0.426324623396176 SERPINB3 other 1 1 1 -0.489883200507879 0.796096260920231 0.0230095309725734 70.3755074092051 26.3069190915035 2.67517101354277 0.00769399960624253 158.722043527166 180.781576291821 0.877976875646635 0.380343861673509 SOAT1 other 1 1 1 2.67517101354277 0.877976875646635 5.97314704339405e-10 193.761416458783 30.3457977490315 6.38511526575264 3.88667915259204e-10 -106.827889993019 138.13966600887 -0.773332476322619 0.439687469735002 PKP2 other 4.95233621367801e-06 1 4.39544545366634e-06 6.38511526575264 -0.773332476322619 6.97661048281113e-07 -4.77034470915327 13.6047635274377 -0.350637826194668 0.72599580969292 -206.520185279083 38.9854538564026 -5.29736516701257 1.70889742140947e-07 F7 other 0.00472735126315282 0.00223763028359356 1 -0.350637826194668 -5.29736516701257 3.95250859730689e-30 1602.23021499472 132.288051669965 12.1116774702525 4.62263484736177e-30 -476.623868739608 573.903700046336 -0.830494504045061 0.406623578643443 GDI2 other 5.4117747714326e-26 1 6.79712227956075e-26 12.1116774702525 -0.830494504045061 0.699851209848688 -7.80492351160519 13.8372674340909 -0.564050926151517 0.572958523555453 11.2279387561605 37.3778866791381 0.300389876306923 0.763997796589004 PRDM1 other 1 1 1 -0.564050926151517 0.300389876306923 1.40701143736308e-101 238.928021028898 9.73345601003817 24.5470900348745 2.15016467579122e-89 -41.4261662425595 32.5332348189366 -1.27334912968589 0.203453426860249 ATG5 other 2.1980332674486e-97 1 3.35361184483156e-85 24.5470900348745 -1.27334912968589 1.12597601314385e-14 120.834153331014 34.1573042888777 3.53757873598826 0.00043825015066753 -242.500622547387 54.0806311147019 -4.48405681570278 8.93447839168583e-06 PITHD1 other 1.14759475259621e-10 0.108241205715274 1 3.53757873598826 -4.48405681570278 9.21094323953763e-15 134.304828324357 35.016251036699 3.83549992783631 0.000140012300821915 -745.596773297717 113.057676727788 -6.59483544043548 1.01124259662684e-10 MTA3 other 9.42187383972305e-11 1.44547016761841e-06 1 3.83549992783631 -6.59483544043548 0.000162586256965594 210.093709493348 50.1340131867548 4.19064216364896 3.25786601877545e-05 81.6956137507141 201.054633746102 0.406335393661615 0.684659889534406 USP13 other 0.859593540577096 1 0.281772831963889 4.19064216364896 0.406335393661615 0.000191323848437298 309.871836597007 75.5870033223556 4.09953858437141 4.77550942559645e-05 178.711880304118 316.834511534794 0.56405433687893 0.572950903296825 ATP11B other 1 1 0.406204831741234 4.09953858437141 0.56405433687893 0.0249529640481093 206.958983274077 107.045573796433 1.93337263685136 0.0537078748523775 1518.49267860508 752.376998302764 2.01826036950963 0.0440535322913911 LAMC2 other 1 1 1 1.93337263685136 2.01826036950963 0.0362299642273394 2.68964125362209 32.7596875955799 0.082102164307116 0.934595782243822 -258.289821511512 105.366762481314 -2.45134058814152 0.0145471659660982 CDK14 other 1 1 1 0.082102164307116 -2.45134058814152 1.02845410508918e-21 1852.10414256011 199.299299652132 9.2930790313507 3.70836815806826e-19 -1535.81186053778 650.21232212368 -2.3620159266155 0.0185310352486333 SEC61A1 essential 1.26047335119729e-17 1 5.05079743128897e-15 9.2930790313507 -2.3620159266155 2.80937048840503e-17 284.886428687121 33.8498368114327 8.41618322339744 3.60109712672258e-16 -183.168828228724 119.504282734632 -1.5327386101757 0.125933586329869 PPP1R12A essential 3.11165875295742e-13 1 4.70231262807435e-12 8.41618322339744 -1.5327386101757 0.000103721598077324 42.2006504936244 11.2488226554011 3.75156154438631 0.000194638588855507 82.6278625000851 27.3159971532334 3.02488911668028 0.00260494686587428 RASGRF1 other 0.561963618382942 1 1 3.75156154438631 3.02488911668028 0.209366330703054 33.8200022883007 35.8276707717564 0.943963187106254 0.345615347320837 -182.710986808372 142.005614118894 -1.28664622129233 0.198775124495549 CAMK2B other 1 1 1 0.943963187106254 -1.28664622129233 1.09448913404907e-07 22.6269159743161 36.9061953876957 0.613092618640929 0.540070859765793 -267.119590071073 59.1373525771729 -4.51693520981495 7.69671873828772e-06 CROCC other 0.000789673910216404 0.0935767064201021 1 0.613092618640929 -4.51693520981495 0.00689583776857364 248.483886035007 78.6070346362223 3.16108968090376 0.00165997960049492 80.9020614304291 661.363559593934 0.122326155193827 0.902686228503576 ATP2B4 other 1 1 1 3.16108968090376 0.122326155193827 5.35015455261012e-24 707.102670978954 65.007595912426 10.8772315150912 4.76518632723737e-25 -427.791721519185 544.889086042441 -0.785098715458333 0.432740635311618 ZC3H11A other 6.80807166819637e-20 1 6.82851200693115e-21 10.8772315150912 -0.785098715458333 1.9327166294106e-41 101.272101597274 12.6474722627002 8.00729975869915 7.10717381363871e-15 -249.01593207345 29.2590285031794 -8.51073821697091 1.67418147796151e-16 RIOK2 essential 2.84766468177358e-37 2.53923104762422e-12 9.068753786203e-11 8.00729975869915 -8.51073821697091 5.17412420654026e-10 84.5534952488023 40.8733376682457 2.06867116982452 0.0390514347478776 -494.715120666557 91.9770684537418 -5.37867893577587 1.11847675047932e-07 YIPF1 other 4.3059061646828e-06 0.00147773148273328 1 2.06867116982452 -5.37867893577587 6.13904405440565e-28 663.036435258624 59.3474748545454 11.1721086176566 3.21975002292839e-26 -44.6933853429624 133.549327475011 -0.334658258397634 0.738012597881786 NDC1 other 8.23061636374166e-24 1 4.64416743307191e-22 11.1721086176566 -0.334658258397634 4.83427659337444e-05 8.79763583641744 2.17911890616093 4.03724450811026 6.18627135607481e-05 17.969048510859 8.81438317029196 2.03860532991372 0.041973301773431 DGKG other 0.273958454546529 1 0.521440812603546 4.03724450811026 2.03860532991372 3.07866352176067e-19 119.488439615811 16.3006831672963 7.33027189041607 8.38089151608847e-13 -252.003566754329 74.1984671495059 -3.39634464747844 0.000732918625821076 FLYWCH1 other 3.58325647297724e-15 1 1.01987068859281e-08 7.33027189041607 -3.39634464747844 1.43568347928195e-24 127.180403183765 13.8528278765173 9.18082606074648 9.02785020733603e-19 -171.971609256439 62.8085452342014 -2.73802885602889 0.00638443497286535 UNKL other 1.8442789974856e-20 1 1.22489871613135e-14 9.18082606074648 -2.73802885602889 0.517371894363393 0.670832583143714 11.5238585275221 0.0582124972761148 0.953600664134095 -39.7949922528804 37.2150233901818 -1.06932600406155 0.285395302429809 TBXAS1 other 1 1 1 0.0582124972761148 -1.06932600406155 2.01888210522896e-06 186.015206111728 38.0586544708952 4.88759281424363 1.34450239256989e-06 -7.75528047354543 123.638544541107 -0.0627254267860373 0.95000814697617 PARP12 other 0.013120714801883 1 0.0128440313562202 4.88759281424363 -0.0627254267860373 2.1874017725622e-06 437.575401904166 110.918266647549 3.94502560425501 9.01983009625361e-05 -316.956419592299 215.386039920948 -1.4715736438101 0.141712159700045 ALDH18A1 other 0.0141656138791128 1 0.748104708183274 3.94502560425501 -1.4715736438101 2.91290231745605e-07 207.912313472889 37.5817613792929 5.53226633990193 4.92593064940114e-08 -70.9303185376522 227.001181976451 -0.312466736604968 0.754806019021075 TARBP1 other 0.00203378839804781 1 0.000511705675859791 5.53226633990193 -0.312466736604968 1.31647913090492e-38 125.909210996703 12.1434104719926 10.3685213710842 4.38858687539283e-23 -145.329554755012 27.3732218678939 -5.30918703893857 1.6144835285984e-07 GATB other 1.91560878337975e-34 0.00211707225105108 6.200195537555e-19 10.3685213710842 -5.30918703893857 0.319877634776413 7.38467427301818 36.687647772537 0.201285029740884 0.840550808081736 -179.513664312867 123.827060974501 -1.44971271142285 0.147713840159934 MXD1 other 1 1 1 0.201285029740884 -1.44971271142285 3.86412344324786e-14 142.5128191935 33.9192025140243 4.20153802656701 3.09902200028985e-05 -518.336479407595 92.5639926079402 -5.5997636316644 3.41275043204141e-08 CDK17 other 3.86064573214893e-10 0.000458434765536123 0.268623226985124 4.20153802656701 -5.5997636316644 2.02492468002021e-19 9.61992160174512 7.055918488817 1.36338332379999 0.173325693938469 -131.014981269099 15.2440310879185 -8.59451023902286 8.89653319847319e-17 DNAJC25 other 2.36916187562364e-15 1.35165028884403e-12 1 1.36338332379999 -8.59451023902286 0.216514499130846 55.9179279804607 32.0359341615359 1.74547518104213 0.0814678115036666 64.1747814133761 114.145827728471 0.562217495728661 0.574199849183467 SLC2A3 other 1 1 1 1.74547518104213 0.562217495728661 0.0238368906453407 5.08969325509608 9.14871871432781 0.556328532335912 0.578216313858397 -44.0306907139731 18.8859425579514 -2.33140022420725 0.0200985796893535 PSD other 1 1 1 0.556328532335912 -2.33140022420725 3.78947158156645e-22 99.7401047031187 17.6934775076572 5.63711145307383 2.85505246273972e-08 -196.229814645526 36.4221944413577 -5.38764392577909 1.08875455511394e-07 CTDP1 other 4.68151319186719e-18 0.00143900689549409 0.000299980362260062 5.63711145307383 -5.38764392577909 2.55624159759755e-25 1687.40811254224 152.120899074006 11.0925462761125 6.5255912120958e-26 854.324863505179 546.423116643418 1.56348594611653 0.118520920192581 YBX3 other 3.31672347288282e-21 1 9.39554622717553e-22 11.0925462761125 1.56348594611653 1.9626460510508e-10 39.5995340570097 6.10162333324792 6.48999977452406 1.93146445832938e-10 -4.0905490322673 21.9878887813751 -0.186036461842222 0.852485389404079 STYK1 other 1.67237070010039e-06 1 2.20457353273715e-06 6.48999977452406 -0.186036461842222 5.16979433981604e-28 1527.46537748893 139.010172652107 10.9881553870998 2.09802926240712e-25 -1082.00177742108 553.439163026402 -1.95505097887239 0.0511113355817855 WNK1 essential 6.93734702459915e-24 1 3.01130140033294e-21 10.9881553870998 -1.95505097887239 6.37285967195996e-10 204.886855602745 41.8011498094784 4.90146458976799 1.2585598560657e-06 -280.254292736861 104.058258166723 -2.69324412761008 0.00729515767496627 CCAR1 essential 5.27354137854686e-06 1 0.0120444178225487 4.90146458976799 -2.69324412761008 1.21650262740287e-30 359.835776461669 29.1892041742097 12.3277008278151 8.71079529939775e-31 -172.098846220743 210.705056991291 -0.816776059759476 0.414433342503097 OGFR other 1.67402926556909e-26 1 1.28449387484919e-26 12.3277008278151 -0.816776059759476 0.080284240403766 38.2956681166018 18.1850894598893 2.10588285535082 0.0356713065310873 60.1746056272989 36.6559957371175 1.64160335621074 0.101249118149563 GNA15 other 1 1 1 2.10588285535082 1.64160335621074 8.12658415095043e-18 -15.4757328188535 20.9278451217276 -0.739480473447617 0.459934262610045 -264.860441571739 32.5095426466389 -8.14715988011977 2.56918383339635e-15 PIGV other 9.13428058566828e-14 3.86893393471157e-11 1 -0.739480473447617 -8.14715988011977 0.0429671203760033 187.683562426376 104.125881774434 1.8024679285113 0.07202825030266 -117.681780244962 170.088227947833 -0.691886685309318 0.489305316810884 PTPRU other 1 1 1 1.8024679285113 -0.691886685309318 3.53469129131194e-18 177.54653057922 28.8690083701251 6.15007375047051 1.51163245655722e-09 -179.969661592286 49.7828048414981 -3.61509686256702 0.000328451228830889 SNRNP40 essential 4.00692604783122e-14 1 1.66884223203917e-05 6.15007375047051 -3.61509686256702 0.780759248860201 -0.487904780662972 9.16440069754426 -0.0532391366075595 0.957560917863361 14.0280939313733 21.5225667818115 0.651785359691777 0.514814914186075 RIMBP2 other 1 1 1 -0.0532391366075595 0.651785359691777 0.315167621830287 426.563567003254 644.353111253124 0.662002804911863 0.50826902008394 -1148.21698371907 1219.59830461383 -0.941471449554561 0.346909913869472 COL11A1 other 1 1 1 0.662002804911863 -0.941471449554561 4.08491944370526e-18 345.239850281467 38.1380176377347 9.05238058151923 2.55830101178158e-18 -56.3490330795655 170.810958305629 -0.329891206269924 0.741610575940534 QSER1 other 4.62372031832999e-14 1 3.45191555519689e-14 9.05238058151923 -0.329891206269924 1.48317602898173e-16 116.266068516137 16.738414212715 6.94606233533269 1.07417989159984e-11 -49.6443289328342 34.9542652775922 -1.42026526773141 0.156102269066302 MPC1 other 1.60687290979881e-12 1 1.27365509746992e-07 6.94606233533269 -1.42026526773141 2.42877498506071e-20 99.3423843003261 53.307078538516 1.86358710745231 0.0629192643205625 -866.158744078253 106.960683248574 -8.09791708290906 3.70158578148146e-15 ACAA1 other 2.89534265969087e-16 5.56496406387922e-11 1 1.86358710745231 -8.09791708290906 0.0577603512347757 71.1433410420704 30.5450117375381 2.32913123927987 0.0202256320805519 130.808865757302 123.078997835776 1.06280411814727 0.288352982469187 BCAT1 other 1 1 1 2.32913123927987 1.06280411814727 7.85583366625902e-10 80.5532064253092 57.3148127930852 1.4054517933456 0.16046848885497 -957.896521023873 163.950585647805 -5.84259285954371 8.9432141344424e-09 HDAC7 other 6.46535110733117e-06 0.000122468374357054 1 1.4054517933456 -5.84259285954371 0.0369052693203086 -25.3095615462476 17.6278919060439 -1.43576791150903 0.15164313623683 -92.2647674290428 35.9596137320666 -2.56578861265038 0.0105608840800676 LZTS1 other 1 1 1 -1.43576791150903 -2.56578861265038 0.375332841954519 -5.43955929043822 18.1947968787036 -0.298962353177189 0.765082733338095 -56.6495043280045 40.988258105292 -1.38209104135339 0.167509927975065 PRDM6 other 1 1 1 -0.298962353177189 -1.38209104135339 3.61838379174748e-10 35.5439273998755 5.32425551767422 6.67584928670029 6.24522288106614e-11 7.83075675041503 28.295946000588 0.276744829462577 0.782084553852893 SPAG4 other 3.03510032451778e-06 1 7.23259261856269e-07 6.67584928670029 0.276744829462577 2.04823730208357e-11 774.057333035481 138.525249063957 5.58784292586329 3.65072917170992e-08 -1104.54788022455 373.92188943803 -2.95395351656087 0.0032740421558478 NCKAP1 other 1.82887108703042e-07 1 0.000381428183860252 5.58784292586329 -2.95395351656087 7.32318379448033e-80 525.658588831893 24.1665528565089 21.7514923188689 8.96296176342118e-76 -442.406155280952 135.338581734196 -3.268884228075 0.00114858894035097 MRPS35 essential 1.13904800739347e-75 1 1.39409907268253e-71 21.7514923188689 -3.268884228075 0.0132793926130523 50.5249400737271 18.7685867960862 2.69199490737699 0.0073213577957142 90.0480211048311 42.0852300844487 2.13965851972627 0.0328266648698582 GUCY1B3 other 1 1 1 2.69199490737699 2.13965851972627 1.57441582914869e-16 102.790710650562 22.4749584423308 4.57356621656572 5.9472587288605e-06 -300.954456487513 52.6485275064601 -5.71629389730957 1.79940807939745e-08 SFSWAP essential 1.70399025188763e-12 0.0002439817414855 0.0544768899563622 4.57356621656572 -5.71629389730957 0.00190077710882969 107.334644998067 42.7202742510325 2.51249896869455 0.0122843474519765 -511.611569451029 204.988879540689 -2.49580158005341 0.0128707258301978 TNK2 other 1 1 1 2.51249896869455 -2.49580158005341 9.13053347628922e-10 85.0265429224944 35.8586137332456 2.37116090306815 0.0180881938982408 -577.109098232907 107.024232368885 -5.39232177105235 1.04844488470582e-07 MON2 other 7.48795050390479e-06 0.00138646351553497 1 2.37116090306815 -5.39232177105235 2.53188333498249e-12 1010.83327643176 177.533327540669 5.69376629410722 2.04390577275144e-08 -205.203649363392 396.797068822844 -0.517150113966714 0.605263518991662 CDH3 other 2.35439831320022e-08 1 0.000215999962064372 5.69376629410722 -0.517150113966714 9.49324665527371e-39 274.556508054532 47.5212055977258 5.77755771557428 1.28505278079323e-08 -1048.78379298908 109.333711085289 -9.59250154941633 3.21353677838396e-20 GPBP1 other 1.38231164547441e-34 4.95206017548968e-16 0.000136986626432558 5.77755771557428 -9.59250154941633 0.499757824574037 93.4547660322355 95.9104631090268 0.974395941827538 0.330321915351817 -160.290384001761 425.838540274913 -0.376411171939206 0.706767784335875 DGAT2 other 1 1 1 0.974395941827538 -0.376411171939206 1.01490914744781e-10 13.1826081961759 4.59408300775534 2.86947540432382 0.00427105990900907 -80.0179118331498 15.4413009907986 -5.18207059630741 3.09534975317829e-07 ZNF112 other 8.74547212355779e-07 0.00401343048997097 1 2.86947540432382 -5.18207059630741 3.41632184633922e-10 610.915408686386 93.1239075523094 6.56024242048932 1.26757093122018e-10 58.6410936190945 274.748536135666 0.213435508861596 0.831068444530373 CS other 2.86936871874032e-06 1 1.45618548578574e-06 6.56024242048932 0.213435508861596 0.416832912918649 -7.23468241346665 5.80241203922093 -1.24684051469706 0.212996520668625 -2.1431702614545 9.88554222317764 -0.216798453040807 0.828447297861475 LTK other 1 1 1 -1.24684051469706 -0.216798453040807 3.43720338758619e-08 197.603161609906 34.3935119150351 5.74536156988155 1.52678994104668e-08 -35.3420466987644 135.469930637313 -0.260884806927258 0.794279888705139 MRPS24 essential 0.000257343417628578 1 0.000162297770733263 5.74536156988155 -0.260884806927258 6.38553010810249e-33 276.630307331 22.8334757477339 12.1151203779589 5.05369593629776e-30 -428.085871299888 139.015793602359 -3.07940457847822 0.00218064489369797 ELMO2 other 8.97358546091643e-29 1 7.42994376554497e-26 12.1151203779589 -3.07940457847822 1.25162238163988e-14 303.533122136531 57.1675555110149 5.30953474262244 1.60824940399829e-07 -530.080843702629 125.154318173536 -4.23541793394323 2.68187610847328e-05 WAPL other 1.27402642227123e-10 0.314932711418017 0.00162256282369387 5.30953474262244 -4.23541793394323 9.63033958321046e-27 168.859159733892 17.3578363179473 9.72812259782047 1.31896510846674e-20 -598.383652285817 119.276703740366 -5.01676885360899 7.30463258861116e-07 APPBP2 other 1.27380501667125e-22 0.00933678137476279 1.82426064152034e-16 9.72812259782047 -5.01676885360899 8.94555116410564e-05 94.3081354922078 21.7264159201026 4.34071297534851 1.69328647428662e-05 104.004553764159 76.7290743637108 1.35547775894125 0.175826843492144 POLD1 other 0.488874371118373 1 0.149652658597452 4.34071297534851 1.35547775894125 0.720783002223552 -12.8248891188088 20.6456531112161 -0.621190768328927 0.534750564720131 -56.1968381172647 81.9400977306367 -0.685828302304467 0.493131809290307 SEZ6 other 1 1 1 -0.621190768328927 -0.685828302304467 2.20612818317932e-13 161.029757325364 184.594824643337 0.872341668497455 0.383409716941618 -3983.36817604135 547.426623556129 -7.27653351999042 1.21380257181923e-12 EIF4B essential 2.14126801459385e-09 1.78186217543064e-08 1 0.872341668497455 -7.27653351999042 1.75576750524998e-10 15.9128566519135 2.3281228180097 6.8350589276546 2.19816863452672e-11 11.3264024143801 8.19420371712334 1.38224564648197 0.167461456919239 SLC6A16 other 1.49907429598243e-06 1 2.58218869497853e-07 6.8350589276546 1.38224564648197 4.61337849102282e-13 34.7551307968925 11.1802046013523 3.10863101670684 0.00197897085602202 -179.956733518709 31.7691588554048 -5.6645104876012 2.40388298563554e-08 BICRA other 4.41361920236153e-09 0.000324668436039937 1 3.10863101670684 -5.6645104876012 2.63677636114275e-10 55.2097666555086 11.4182812835785 4.83520814423356 1.73432274004035e-06 -120.262529503523 36.412250410187 -3.30280408787581 0.00102024301740926 SPHK2 other 2.22807602516562e-06 1 0.0164448482210626 4.83520814423356 -3.30280408787581 4.67656182002776e-05 1591.14444797136 496.054713731654 3.20759868604354 0.00141751350355102 -3484.55215870113 1581.77066307609 -2.20294397920155 0.0280187534219682 RPL18 essential 0.265862539468578 1 1 3.20759868604354 -2.20294397920155 0.375130309645478 19.4335450702533 23.8340208536554 0.815369978468101 0.415217399775516 -67.2052030455068 76.0110627702771 -0.884150288078676 0.377005675280414 CA11 other 1 1 1 0.815369978468101 -0.884150288078676 5.0840929684056e-36 483.096024407121 35.1846492362291 13.7303066790186 5.73779274417863e-37 184.890765553249 153.363504168795 1.20557212457636 0.228515439305857 ISOC2 other 7.30329954911464e-32 1 8.61300068828655e-33 13.7303066790186 1.20557212457636 1.113596843139e-41 898.90169656852 60.7175067139356 14.8046542952365 7.38501628827465e-42 -103.002458529725 271.566541279796 -0.3792899450879 0.704621942402616 U2AF2 essential 1.64244398394572e-37 1 1.11964231946532e-37 14.8046542952365 -0.3792899450879 9.20894380868919e-34 716.773667287385 55.1328993744287 13.0008339017235 7.63755002666746e-34 -155.909601814853 247.138423362625 -0.630859417542241 0.528397392802285 EPN1 other 1.30205256511056e-29 1 1.13746032547159e-29 13.0008339017235 -0.630859417542241 2.27748564898646e-32 233.731783211411 24.6279968954373 9.49049101328716 7.32345403261804e-20 -865.805958210401 134.528759505636 -6.43584287398508 2.71210630110189e-10 MED29 other 3.18392493728307e-28 3.84658036685281e-06 1.00551023867846e-15 9.49049101328716 -6.43584287398508 1.73471483822344e-06 19.5355465843488 3.8722023553605 5.04507378270266 6.26429382309709e-07 -8.38506559213646 17.0102029691868 -0.492943300401861 0.622259546268844 AHRR other 0.0113363614677902 1 0.00610142218369656 5.04507378270266 -0.492943300401861 0.0145863735287497 55.6291595789962 105.728288029463 0.526152088677482 0.598995794655668 -514.704477084182 206.388510670031 -2.49386206341244 0.012930367038194 GPC1 other 1 1 1 0.526152088677482 -2.49386206341244 1.78686092006948e-26 63.8099028106532 6.93877972221896 9.19612746983808 7.90128210553375e-19 -34.3578037391493 14.5656557932625 -2.35882298928428 0.0186862534053612 ADCK1 other 2.35544006483559e-22 1 1.07283608428937e-14 9.19612746983808 -2.35882298928428 3.75978291705534e-22 219.70864318369 26.0404476329912 8.43720685144199 2.95835949843923e-16 -352.980122399773 119.195546011404 -2.96135329054998 0.00319687863277321 HAGH other 4.64521179402188e-18 1 3.86805504420929e-12 8.43720685144199 -2.96135329054998 3.22587652330197e-34 275.396342193835 40.5221900911248 6.79618602979093 2.84905527184752e-11 -526.902756685948 79.2860777772261 -6.64558988737483 7.39477744347975e-11 RNF4 essential 4.57784137421783e-30 1.05900607768074e-06 3.3351041012247e-07 6.79618602979093 -6.64558988737483 7.5613673011001e-15 79.6023085820663 19.4308338816745 4.09670058767475 4.83136961961925e-05 -286.651035225436 48.0524074651188 -5.96538342919688 4.40791942823434e-09 CASP8 other 7.76476808149969e-11 6.08425118679187e-05 0.410666417667636 4.09670058767475 -5.96538342919688 0.00742122765844123 -54.6091243824264 136.0269053841 -0.401458257307451 0.688239841938608 -825.937381748315 282.65693834457 -2.92204885040347 0.00362134667122131 LIMCH1 other 1 1 1 -0.401458257307451 -2.92204885040347 4.78293709744111e-44 289.29316450597 18.7752185311626 15.4082448641441 1.22303536513381e-44 76.4734398121348 104.555250545842 0.731416542095181 0.464843211022228 INTS13 other 7.11940186954109e-40 1 1.86133752219714e-40 15.4082448641441 0.731416542095181 2.28847047480739e-24 401.051737733782 38.8924914711147 10.3118037071922 7.02278961369072e-23 -412.261595321134 216.600093236873 -1.90333064570884 0.0575288541342903 TM7SF3 other 2.92969990184842e-20 1 9.9091561449176e-19 10.3118037071922 -1.90333064570884 4.63125757652944e-08 25.4300375542487 4.58803301122868 5.54268844448408 4.73773129744589e-08 -18.8112144048652 21.3668101360014 -0.880394138625763 0.379051751837823 DLX3 other 0.000343315124148127 1 0.000492724054934373 5.54268844448408 -0.880394138625763 1.73551540613208e-30 17.2143212772924 14.708228707297 1.17038710913926 0.24236052060287 -247.739896046968 26.301939648863 -9.41907324533298 1.30803934828569e-19 SPA17 other 2.38459816802547e-26 2.01176451766339e-15 1 1.17038710913926 -9.41907324533298 0.151009043622493 1.36617002673712 1.2602949890758 1.08400813982364 0.278839623199153 -2.29329072255902 2.51681142439634 -0.911188935463875 0.362597932978507 TSPAN32 other 1 1 1 1.08400813982364 -0.911188935463875 0.887970257613852 12.9628798329939 36.919391776852 0.351113038680161 0.725641254465557 -66.2266479806717 229.383104518425 -0.288716329477318 0.77290987957193 WISP2 other 1 1 1 0.351113038680161 -0.288716329477318 0.00922925797344586 11.4824012460534 3.75413134512285 3.0586040259275 0.00233482393823545 8.41804654755776 9.07359018841342 0.927752562409886 0.353953510265602 DMRT3 other 1 1 1 3.0586040259275 0.927752562409886 0.137952219300564 19.4647348790133 11.1094787772251 1.75208353779088 0.0803238992551433 46.0790459526115 38.486432371702 1.19728026509654 0.231719744871904 ST3GAL6 other 1 1 1 1.75208353779088 1.19728026509654 4.87415195140148e-10 34.6580907192861 35.358143537578 0.980201086701628 0.327419399331947 -358.835581035521 76.8345669863835 -4.67023626357019 3.78888364970412e-06 ATP2C2 other 4.06070213572519e-06 0.0468002908411453 1 0.980201086701628 -4.67023626357019 0.372216615148077 -23.8992539277336 18.7595461978702 -1.27397825489227 0.203240216666348 -70.4264510266424 83.1589046022996 -0.846890075854786 0.397445980534494 NGFR other 1 1 1 -1.27397825489227 -0.846890075854786 0.000194390381801832 178.344485060862 60.8063755159144 2.93298989699173 0.00349833814693142 -97.5879457050357 112.993618880335 -0.863658909875124 0.38815521634301 CDON other 1 1 1 2.93298989699173 -0.863658909875124 2.86891276120371e-52 281.941951216678 16.3363426667988 17.2585723112727 2.60650488194595e-53 287.305469116722 185.598229665477 1.54799681890588 0.122218823871942 TAF2 essential 4.35673091916396e-48 1 4.00854385794468e-49 17.2585723112727 1.54799681890588 9.29984645545295e-07 130.420451930841 110.765224963431 1.17744943843069 0.239528217057638 -1633.99968505185 358.212475226429 -4.56153762936085 6.27304801652339e-06 HIPK2 ts 0.00623089712515348 0.0766315545698498 1 1.17744943843069 -4.56153762936085 1.69350796206984e-47 511.51796225578 34.4704859847466 14.8393023087093 4.25979299678434e-42 -262.969537119557 127.101355875893 -2.06897507353369 0.03901844220555 TNPO3 essential 2.54534246699097e-43 1 6.46253195542152e-38 14.8393023087093 -2.06897507353369 3.63280301109778e-09 218.867585199611 44.2741476289707 4.9434624249298 1.03190233129005e-06 -342.411452356585 145.287226225671 -2.35678979667989 0.0187972024117226 RFXANK other 2.88807839382273e-05 1 0.00992070901302256 4.9434624249298 -2.35678979667989 1.58765277547907e-14 152.725024113383 20.6791460825002 7.38546086497389 5.92005942543526e-13 -87.3990958987073 66.6557388589763 -1.31120136682631 0.190356449628609 TMEM161A other 1.61019744489087e-10 1 7.23194459411171e-09 7.38546086497389 -1.31120136682631 5.93906227447738e-15 137.673867556846 17.5544547033024 7.84267411798021 2.43596178021232e-14 -15.3117605729898 55.66701339399 -0.275059853932148 0.783377245799338 LPAR2 other 6.12198539253129e-11 1 3.07515815134004e-10 7.84267411798021 -0.275059853932148 1.19903031877087e-27 663.89469932176 56.8802326660507 11.6717999945526 3.32557635845919e-28 -116.136896574527 365.443328750935 -0.317797281924605 0.7507624811484 CTSA other 1.6028637301329e-23 1 4.85002056117689e-24 11.6717999945526 -0.317797281924605 2.67901094200674e-11 288.925944756687 54.9565676346919 5.25735061689515 2.11716563157818e-07 -567.054546593439 182.116083386651 -3.11369834035759 0.00194664382030957 SUGP2 other 2.37869381540779e-07 1 0.00212351712847292 5.25735061689515 -3.11369834035759 9.29518438790104e-05 13.3340117818427 337.221560993813 0.0395408043974015 0.968473675204738 -3178.26848542345 792.347687163393 -4.01120434490276 6.88290941161899e-05 SLC12A2 other 0.507331163891639 0.78527113477161 1 0.0395408043974015 -4.01120434490276 4.54860451922468e-11 36.9540908754132 12.8478171191178 2.87629334483791 0.0041809525969458 -142.517661844208 29.0232317396748 -4.91046838348418 1.20205985997514e-06 SNX24 other 3.99049074471582e-07 0.0152072592885455 1 2.87629334483791 -4.91046838348418 0.0436535425503286 68.6515973757585 27.5874459129195 2.48850863514002 0.0131310869553138 13.8846469245253 168.373450748281 0.0824633982544132 0.934309065802714 EYA2 other 1 1 1 2.48850863514002 0.0824633982544132 0.00887420398059125 -45.7370485053994 167.119476848759 -0.273678743901232 0.784438538398939 -849.910255500971 301.544209665809 -2.81852620033029 0.00500545447466315 CNN2 other 1 1 1 -0.273678743901232 -2.81852620033029 1.8043174755953e-08 -0.606403669619253 22.5303514870511 -0.0269149671263572 0.978537725172254 -216.099853970615 40.6529338217357 -5.31572591828721 1.57027403011936e-07 ABCA7 other 0.000137488991640362 0.0020601995275166 1 -0.0269149671263572 -5.31572591828721 0.00244812280258126 -14.1996455520417 14.8747488808591 -0.954614136062079 0.340196858362122 93.1058122087635 33.6475898034445 2.76708711538181 0.005848463633185 SNCAIP other 1 1 1 -0.954614136062079 2.76708711538181 1.56717150595983e-15 81.3339611209569 14.8522888178034 5.47619037837871 6.63844445803064e-08 -115.561560679744 32.5919646210133 -3.54570710982046 0.000425186353519056 DDX20 essential 1.64568679840842e-11 1 0.000685419390291664 5.47619037837871 -3.54570710982046 1.87148924263551e-17 419.485790569908 52.607199794199 7.97392357340724 9.48759483217175e-15 -205.088777465751 111.392708859968 -1.84113286735461 0.0661597374184965 BTBD1 other 2.08053459103789e-13 1 1.20824520187707e-10 7.97392357340724 -1.84113286735461 9.29750121523557e-11 141.14639322724 21.1043760674889 6.68801545119709 5.68983540318022e-11 -65.3291322774504 104.116270291687 -0.627463239841643 0.530622330312742 FAR2 other 8.02839229935592e-07 1 6.59565719936651e-07 6.68801545119709 -0.627463239841643 0.00460300732090736 178.122475584088 68.5776635260768 2.59738326483457 0.00965982340739417 -959.859431230321 537.157095289108 -1.78692497902072 0.0745319925663275 BCAS1 other 1 1 1 2.59738326483457 -1.78692497902072 0.000985808780199153 488.829910074264 140.760110621761 3.47278719741709 0.000556069542412336 858.039486516274 314.807825541137 2.7255977040639 0.00662529466524158 CHI3L2 other 1 1 1 3.47278719741709 2.7255977040639 1.72739635949351e-10 17.1818097937485 76.2361247699453 0.225376222172853 0.82177397697233 -804.867772834358 136.732344227448 -5.88644755110391 7.02788894342896e-09 SBNO2 other 1.47519649100746e-06 9.65069709711665e-05 1 0.225376222172853 -5.88644755110391 8.7498816750144e-15 78.2859974955313 10.3610626597309 7.55578844241489 1.79758618002402e-13 -34.5923935011961 26.0471968828265 -1.3280658819761 0.184718435366653 PMS1 other 8.96075382338224e-11 1 2.22613072534175e-09 7.55578844241489 -1.3280658819761 5.82148881505735e-13 335.820970447206 96.2886498057636 3.48764855592673 0.000526778111033337 -1152.53585637031 231.072497548896 -4.98776733966978 8.2334141678662e-07 HMG20B other 5.54496809634213e-09 0.0104967797226126 1 3.48764855592673 -4.98776733966978 0.237228163957329 7.61378320418565 46.3975729769888 0.164098738698288 0.869715739711169 -190.122423319968 119.279398533057 -1.5939250671798 0.111546723383051 CALCRL other 1 1 1 0.164098738698288 -1.5939250671798 6.82326248327335e-31 219.337377459108 19.3410679026255 11.3404998402044 6.5625622876765e-27 -97.177464615987 65.316263384324 -1.48779889694838 0.137382276547713 TAF11 other 9.41200826942726e-27 1 9.50127768009804e-23 11.3404998402044 -1.48779889694838 1.42140194976521e-16 210.34591516441 30.2369815452956 6.95657782008789 1.00308607318817e-11 -285.018283674798 101.005857671248 -2.82179954951198 0.00494975382630526 ANKS1A other 1.54151041452037e-12 1 1.19046255165972e-07 6.95657782008789 -2.82179954951198 1.18392224724645e-24 287.056275017372 97.7641534679141 2.93621194307772 0.00346845625562467 -1426.56308372055 178.367532822312 -7.99788538389261 8.16080555743111e-15 AP3D1 other 1.52252400995894e-20 1.22354957722565e-10 1 2.93621194307772 -7.99788538389261 3.78138774483175e-14 83.2942437773013 18.4855628991255 4.50590789319386 8.09229759468848e-06 -298.58432724628 61.7505465075919 -4.83533092633553 1.7316551218358e-06 ZNF76 other 3.77911891218485e-10 0.0217443933648922 0.0734214160766086 4.50590789319386 -4.83533092633553 1.29626455609094e-13 645.515423478276 103.107887849608 6.26058235641312 7.79704555382215e-10 -1183.64818673746 471.735625955151 -2.50913461187262 0.0123928374126255 SLC9A3R2 other 1.27085777079156e-09 1 8.71787663372854e-06 6.26058235641312 -2.50913461187262 2.04242955381262e-18 164.622427594122 18.505034460094 8.89608868057657 8.59473709421664e-18 12.392074831694 84.6635906952808 0.14636840618177 0.883684889381357 NTHL1 other 2.33041212090019e-14 1 1.15238234959257e-13 8.89608868057657 0.14636840618177 2.12182910741117e-13 196.676655223726 31.8542790367993 6.17426170582979 1.29971326146895e-09 -280.670013773099 108.518246792799 -2.58638544270808 0.00995697085164065 UHRF1BP1 other 2.06135697784995e-09 1 1.44021226503375e-05 6.17426170582979 -2.58638544270808 1.69782826835952e-34 1238.81677277608 93.9173868477669 13.1904944798358 1.39530865336284e-34 453.588083637065 231.79441972052 1.95685506227444 0.0508861629258129 IPO5 other 2.41380244912673e-30 1 2.08277722687472e-30 13.1904944798358 1.95685506227444 1.03073281439015e-05 622.423026419231 193.766390005811 3.21223420842265 0.0013954087572208 -816.408257600241 377.12491364757 -2.16482186155219 0.0308378938129469 OAT other 0.0626067111460577 1 1 3.21223420842265 -2.16482186155219 6.76607473669756e-30 394.412942482892 35.3542790149469 11.1560171349031 4.31621275714637e-26 -163.968908059581 107.566453099295 -1.52434986313271 0.12802118760841 WDR3 essential 9.24922416506556e-26 1 6.22052582559935e-22 11.1560171349031 -1.52434986313271 1.24295236215605e-15 257.738220955671 44.8141736234656 5.75126572948149 1.47869358032412e-08 -316.895674674183 90.3705931715363 -3.50662382034684 0.000491313716462445 PKN2 other 1.31019608494869e-11 1 0.000157244275331667 5.75126572948149 -3.50662382034684 9.48406916248262e-09 120.960223618592 37.3397927495413 3.23944550067377 0.0012731499561668 -202.598492614107 67.0569112772669 -3.02129174689247 0.00263921913975762 WDR18 essential 7.34446315942654e-05 1 1 3.23944550067377 -3.02129174689247 2.09642869325749e-07 144.623890968194 31.8626254040778 4.53898224437226 7.00081436655079e-06 -237.055256500104 130.351379936963 -1.81858647460995 0.0695387964024713 TRAM2 other 0.00148175580039439 1 0.063819423765477 4.53898224437226 -1.81858647460995 7.43137952931685e-07 229.971798049027 48.7893932847765 4.71356134122667 3.09886293136729e-06 -21.0168439553318 85.9004041112581 -0.244665251261342 0.806808233186308 NTN1 other 0.00502361256181819 1 0.0289154900125882 4.71356134122667 -0.244665251261342 1.0224603454869e-58 258.232233615495 13.9292359048537 18.538865690796 8.26153962382903e-60 263.325113313303 76.7008773864461 3.43314343050573 0.000642141804578647 MCM10 other 1.5682496779078e-54 1 1.27632525648535e-55 18.538865690796 3.43314343050573 0.063067425018736 -3.09709978044249 17.7417865091683 -0.174565271588745 0.861486666328026 -119.765517416317 51.8926422331834 -2.30794795297071 0.0213790893274747 DGKA other 1 1 1 -0.174565271588745 -2.30794795297071 5.69983862756824e-24 1269.1757797311 305.078911801659 4.16015571917415 3.69956235156321e-05 -7671.70823671807 896.113718709411 -8.56108781346068 1.16743352202704e-16 ERBB3 other 7.24677483109027e-20 1.77239757314145e-12 0.318162362234436 4.16015571917415 -8.56108781346068 0.000277151998540749 72.3004247328681 19.23493054139 3.75880872443449 0.000189086621199181 140.21404222071 61.1834927496422 2.29169725230388 0.0223022124781812 ROPN1 other 1 1 1 3.75880872443449 2.29169725230388 0.407226751175677 7.00381260571301 5.50915354963476 1.27130466461174 0.204169633862428 -1.98305977848796 14.2173648451813 -0.139481528404335 0.889121849641692 ANKRD44 other 1 1 1 1.27130466461174 -0.139481528404335 1.48398187686008e-63 704.508129113973 75.7900689801292 9.29552035766959 3.48381652174001e-19 -1356.88121254631 165.677818212023 -8.18987856787116 1.86184802448605e-15 KARS essential 2.28844845230593e-59 2.80580497290048e-11 4.74704839252294e-15 9.29552035766959 -8.18987856787116 1.48818118022246e-40 179.073640484654 17.9696236689406 9.96535285233446 1.32562940938281e-21 -108.216720074229 39.2817698099969 -2.7548840237511 0.00606720749017126 ADAT1 other 2.18405470009448e-36 1 1.84925302608902e-17 9.96535285233446 -2.7548840237511 8.86217501119063e-21 103.638415275817 12.2379050298937 8.46864026339954 2.3406893084279e-16 -97.7892877660462 41.4673319238538 -2.358224733282 0.0187167373304689 TBC1D22B other 1.0666513843469e-16 1 3.06583485617886e-12 8.46864026339954 -2.358224733282 1.15821738937112e-15 399.813618718301 54.5171220446904 7.33372569429754 8.15008076887826e-13 -552.429351735522 175.265114579356 -3.15196411482899 0.00171092333502071 NDUFB4 essential 1.22203516752547e-11 1 9.92272333610928e-09 7.33372569429754 -3.15196411482899 4.38505946832528e-11 196.409259776354 87.4116446196612 2.24694616639413 0.0250511026648565 -653.61618189615 140.894029220077 -4.63906231878144 4.40762074700289e-06 SPEN other 3.85052071913643e-07 0.0543018876030756 1 2.24694616639413 -4.63906231878144 0.513639786639736 18.2947156824557 247.181755470314 0.0740132120497575 0.941027078924095 -917.89800772493 821.727539321048 -1.11703449598798 0.264472679471105 MYLK other 1 1 1 0.0740132120497575 -1.11703449598798 6.01107651795087e-15 304.861054785995 40.2349158893274 7.57702726717671 1.57917847036856e-13 -161.763069853772 102.782861888203 -1.57383309709475 0.116120520662209 ZC3H15 other 6.19501545940017e-11 1 1.95818130325701e-09 7.57702726717671 -1.57383309709475 1.26607147335184e-42 142.870929625586 46.3723378577528 3.08095162387203 0.00217015250036966 -962.869943287477 81.5997013408874 -11.7999199441311 1.0485820108135e-28 MAP2K4 other 1.87429220915007e-38 1.63935311570582e-24 1 3.08095162387203 -11.7999199441311 1.41591510282068e-07 42.2833783334163 7.49965596904988 5.63804239926663 2.78238697470688e-08 70.4891093605156 46.3951093449322 1.5193219793158 0.129269993158251 TMEM206 other 0.00101393680512989 1 0.000292512342650935 5.63804239926663 1.5193219793158 1.03886929419919e-15 437.956598897587 70.1309125006842 6.24484386814893 8.54471664217013e-10 -489.440213784374 146.359175256382 -3.34410338762163 0.000882241694056685 SLK other 1.09818873089796e-11 1 9.53846718765452e-06 6.24484386814893 -3.34410338762163 2.82260936793496e-13 51.0697022381617 13.5073337311589 3.78088697996359 0.00017383484727491 -111.065847448044 29.6486953327487 -3.74606188237109 0.0001991021826812 CYB5R4 other 2.72889873691952e-09 1 1 3.78088697996359 -3.74606188237109 2.32635404383159e-18 115.052031065662 23.9446363596292 4.80491870236295 2.00333612961941e-06 -289.766982765638 49.5959359884306 -5.84255497936833 8.84109161015909e-09 GSTO2 other 2.65041516213733e-14 0.000121078749601129 0.018923513080385 4.80491870236295 -5.84255497936833 8.48279758278671e-56 111.338212967768 6.19034834268692 17.9857750815104 5.31217128584037e-57 45.5185001629517 35.8274425987227 1.27049258504916 0.204457336804189 SEC61A2 other 1.29532319089153e-51 1 8.19296177415161e-53 17.9857750815104 1.27049258504916 0.981357623596505 0.75223546620463 7.72289276605579 0.0974033291658417 0.922441910457664 6.04332243930255 33.4964917240473 0.180416578819328 0.856892605619954 PRKCQ other 1 1 1 0.0974033291658417 0.180416578819328 2.54141915278956e-06 121.833367112321 45.6669954014147 2.66786474655057 0.00786065305540513 -267.891924032792 95.5441136802954 -2.8038558704851 0.00522955182612551 TLE2 other 0.0163464079907425 1 1 2.66786474655057 -2.8038558704851 2.73573810191807e-06 38.1911458044228 17.8472744324867 2.13988673446433 0.0328048741277865 -123.217685939184 34.5396309211659 -3.56742914307392 0.000392078921972564 ASB1 other 0.0175442884476006 1 1 2.13988673446433 -3.56742914307392 0.369470242692702 52.4540993417106 96.2336700841374 0.545070132894753 0.585928673357914 -525.745240746157 436.359360001514 -1.20484465085001 0.228787161721011 FAM107B other 1 1 1 0.545070132894753 -1.20484465085001 2.12857631694557e-05 221.078991446903 50.385945843829 4.38771144898493 1.38129343515822e-05 106.393726124635 110.124164782624 0.9661251582216 0.334419707920665 ME1 other 0.125437002357602 1 0.123087058006949 4.38771144898493 0.9661251582216 0.00064726951124698 144.78957344495 81.7627382695838 1.77085034710502 0.077144474491576 601.18502285508 156.118206478362 3.85083224062277 0.000131695158786203 TBC1D1 other 1 1 1 1.77085034710502 3.85083224062277 2.71193456179415e-12 127.91096419923 26.0969094791673 4.90138360258093 1.25654900189281e-06 -421.57363058041 99.0565793731645 -4.2558872237276 2.45078127896468e-05 CDK13 other 2.52047198173149e-08 0.288530479972511 0.0120302001441218 4.90138360258093 -4.2558872237276 1.14623426278403e-16 971.241170000966 112.262405755632 8.65152642564172 5.78745218791836e-17 -216.906161053006 381.644368349257 -0.568346290530106 0.570035240655817 MTHFD2 other 1.24733212476158e-12 1 7.66258669680391e-13 8.65152642564172 -0.568346290530106 1.33215863131377e-25 142.017601819824 16.5032465479366 8.60543417365237 8.21444503078801e-17 -299.663731799087 59.0115656222224 -5.07805086408758 5.24943148300452e-07 FOXJ2 other 1.73526983314932e-21 0.00674814417140231 1.08496389966648e-12 8.60543417365237 -5.07805086408758 1.35537701091326e-17 1726.38418434822 215.327355573256 8.01748658340297 6.70267374294363e-15 -891.048342213987 514.591154645631 -1.73156560148726 0.0839209958631752 YBX1 essential 1.51314289498357e-13 1 8.55529276549325e-11 8.01748658340297 -1.73156560148726 7.43857065483703e-05 54.4583538248967 26.3763881086133 2.0646630463825 0.039430885417113 -322.747629242841 98.2054708179127 -3.28645264418376 0.00108036579448532 PDE4A other 0.411576114332133 1 1 2.0646630463825 -3.28645264418376 1.31676582264986e-13 377.02815794848 48.5381968961232 7.7676589172721 4.08269928718997e-14 -174.234597083264 300.27176735772 -0.580256341168748 0.561985158796077 PPP2R5A other 1.29056218277913e-09 1 5.13113646414036e-10 7.7676589172721 -0.580256341168748 0.519698944680754 -7.40996626885923 6.7315702954381 -1.10077826475063 0.271481801136058 -11.0716062622596 23.2473536592305 -0.476252326374513 0.634086546221267 CTNNA2 other 1 1 1 -1.10077826475063 -0.476252326374513 2.3592374499158e-25 365.361687884602 36.7828677577238 9.93293101264193 1.7234884862418e-21 -166.763254715387 105.033119698386 -1.58772066557926 0.112926299736521 ELAVL1 other 3.06299798122569e-21 1 2.40150885672933e-17 9.93293101264193 -1.58772066557926 0.00333481889030142 -94.1246742602699 28.6261112647762 -3.28807057967696 0.00107429813064706 -119.901550228936 64.4700104236096 -1.85980348756119 0.0634558839707062 TIE1 other 1 1 1 -3.28807057967696 -1.85980348756119 6.09920610336796e-08 275.786350826238 58.3638312898572 4.72529552517854 2.93058406145123e-06 -351.093178588075 171.571470655378 -2.04633775794396 0.0412041915892491 DIP2B other 0.000448635238088624 1 0.027400960974569 4.72529552517854 -2.04633775794396 2.61736785940494e-06 123.352993346026 26.770299459452 4.60783016390475 5.07800266755469e-06 -72.7014959989515 78.2203728082506 -0.929444509004986 0.353072524851672 SMARCD1 other 0.0168165884966767 1 0.0467379365521734 4.60783016390475 -0.929444509004986 3.97224842284888e-17 143.140592801408 46.4696894217407 3.0803001823903 0.00217301814042872 -719.177954965591 102.882278081072 -6.99029967434114 8.10945889997694e-12 KDM4A other 4.38218446008688e-13 1.17887204028965e-07 1 3.0803001823903 -6.99029967434114 1.82608706942221e-22 200.219652576581 31.2779362535311 6.40130636988483 3.34830095716951e-10 -392.69102286092 66.9907796581406 -5.861866735465 7.97241000797329e-09 NFYC other 2.26909579246404e-18 0.000109373492899386 3.79730811552594e-06 6.40130636988483 -5.861866735465 1.09142901427927e-05 4.7547582239612 4.66409158112397 1.01943929300277 0.308451809975978 -46.7679973788957 11.1831958001283 -4.18198860278911 3.37257352037169e-05 ZMYND12 other 0.0661624268456093 0.393005992328913 1 1.01943929300277 -4.18198860278911 0.00413717548137918 12.0196181659089 3.95365186194085 3.0401306401339 0.00248319203360462 -14.7596109933543 17.3680026169128 -0.849816258029668 0.395816096621737 SLC9A3 other 1 1 1 3.0401306401339 -0.849816258029668 0.000316076009901774 47.1589456020101 12.1116364934956 3.89368898474919 0.000110932742175668 53.8424231789013 24.1121418881448 2.23300042894049 0.0259526670222869 NGEF other 1 1 0.912643669879219 3.89368898474919 2.23300042894049 0.0099789517723243 101.042104233978 34.2626749531839 2.94904307302454 0.00332696942247695 224.730604017255 233.291727361781 0.963302927877723 0.335830720845928 ASPM other 1 1 1 2.94904307302454 0.963302927877723 0.597730134350868 -28.8374674930349 29.0779259550874 -0.991730549750216 0.32177315293583 67.9698889452735 290.271203961221 0.23415994427871 0.814949560854104 CD84 other 1 1 1 -0.991730549750216 0.23415994427871 0.690259461994041 -17.8977216143583 20.9371736856541 -0.854829877378417 0.39302654092274 -10.7337093033304 59.2443108166224 -0.181177047304242 0.856296970375925 SPI1 other 1 1 1 -0.854829877378417 -0.181177047304242 1.25671446492614e-21 91.1940767340745 9.4096033500271 9.69159627050718 1.35090926569604e-20 -23.3297989265944 37.3182692823124 -0.625157580328945 0.532129781605577 ZNRD1 essential 1.53633343337221e-17 1 1.86830751445763e-16 9.69159627050718 -0.625157580328945 0.361538335862323 13.0965311973327 12.7787303369103 1.02486951770979 0.305888791413848 -22.192839270904 35.6444569669263 -0.622616843103998 0.533802119070331 MPPED2 other 1 1 1 1.02486951770979 -0.622616843103998 7.54479090173935e-09 101.309079733006 19.8340531134101 5.10783545620887 4.5316611149133e-07 -202.565336539446 69.6734707076337 -2.90735246116068 0.00379538757302477 ZBTB11 essential 5.88493690335669e-05 1 0.00445824820485171 5.10783545620887 -2.90735246116068 1.73094604357885e-24 73.0440972694679 13.9875386234099 5.22208368720567 2.51965990055255e-07 -194.255544348945 28.5386418649665 -6.80675503999401 2.63579897352637e-11 ATXN3 other 2.2194190170768e-20 3.8037214986959e-07 0.00251638434268183 5.22208368720567 -6.80675503999401 3.23822835417462e-30 301.818574102655 42.2820693180171 7.13821671859484 3.02167771883245e-12 -555.584149004415 86.2127487979416 -6.4443386477161 2.54984964660712e-10 GOLGA5 other 4.43863960506715e-26 3.61900160342949e-06 3.63447396021168e-08 7.13821671859484 -6.4443386477161 2.08569422467397e-118 2302.8164580026 75.5570084273262 30.4778670560725 1.63236844976394e-119 1170.07902512749 288.253310849221 4.05920411349423 5.65075569907703e-05 FGFR2 og 3.26327718392489e-114 0.64915881470997 2.55465662388057e-115 30.4778670560725 4.05920411349423 5.42277631755496e-16 105.879921102816 14.1750370419305 7.46946345110898 3.27384392631903e-13 -41.9259210335631 27.7130831216576 -1.51285661178558 0.130903272465439 LRRC40 other 5.78122183214534e-12 1 4.0278101825503e-09 7.46946345110898 -1.51285661178558 9.74581272700065e-06 9.90795378208088 89.8194390906065 0.110309682206834 0.912204386399222 -945.866540962832 212.297577258569 -4.45538075929528 1.01678076823394e-05 ISOC1 other 0.0593422536947069 0.122694935302789 1 0.110309682206834 -4.45538075929528 0.00605674838536223 45.9678907853655 16.8300422710686 2.73129978196109 0.00651366658772406 -18.2099156173285 34.7677666761573 -0.523758566000052 0.600660171053271 EML1 other 1 1 1 2.73129978196109 -0.523758566000052 9.98234107844525e-28 63.0104959534921 7.34330612284281 8.58067128067635 1.01739655063571e-16 -53.0421242011031 16.825992272531 -3.15239204570991 0.00170981041712865 TRMT11 other 1.33583688311754e-23 1 1.34092865373787e-12 8.58067128067635 -3.15239204570991 3.22961808533175e-20 299.773175394124 36.4335495153778 8.2279431837295 1.40414520281248e-15 -593.804154621018 192.998116755886 -3.07673548634722 0.00219773021746033 THUMPD1 other 3.84033886526798e-16 1 1.81275145683091e-11 8.2279431837295 -3.07673548634722 5.66208682552193e-07 71.6495454194114 16.6201063905757 4.31101605101876 1.93063285329109e-05 157.424623264592 34.6896320625669 4.53808858452743 6.99703179559263e-06 MSANTD3 other 0.0038609770063234 0.0852868205564786 0.169953610075215 4.31101605101876 4.53808858452743 0.132263507816092 -5.46775708154046 10.5819070182372 -0.516708101112319 0.605578358696539 -44.1294517685686 22.1851620749448 -1.98914263594255 0.0472059633577801 KIF26A other 1 1 1 -0.516708101112319 -1.98914263594255 2.9797012459228e-20 52.1206089848844 30.6163824817712 1.70237646514629 0.0892560979314418 -526.96642210958 63.4857242718729 -8.30054989768858 8.23287608206638e-16 ATG2B other 3.54614245277272e-16 1.24357593219613e-11 1 1.70237646514629 -8.30054989768858 7.14159673101747e-39 768.244340024717 54.7607606699749 14.0291027850156 3.13759924179546e-38 -950.682077249419 513.980088520567 -1.84964767795937 0.0649229582026924 ARFGEF1 other 1.04038781177462e-34 1 4.72365565852307e-34 14.0291027850156 -1.84964767795937 0.00483592541304249 23.6517246837719 8.03481248195031 2.94365608866466 0.00338289068177847 -81.4137295226842 70.0220924617801 -1.16268632742048 0.245469403695233 ZFAT other 1 1 1 2.94365608866466 -1.16268632742048 1.29340218811815e-60 305.357951296391 16.0735161715738 18.997582609611 1.22389391871028e-61 111.623515760694 147.113165422788 0.758759526653509 0.448336923663953 MTFR1 other 1.98938190554453e-56 1 1.89275194528545e-57 18.997582609611 0.758759526653509 0.0686731761786608 14.0925000525436 16.0289720556014 0.879189258279287 0.379690449031924 -93.487253964418 51.8060668461168 -1.80456189121845 0.0717012997819198 STAG3 other 1 1 1 0.879189258279287 -1.80456189121845 4.56911714955916e-26 236.013556369851 25.6533932869737 9.20009114309625 7.65315759867354e-19 -116.483161029451 53.3960234256359 -2.1814950544337 0.0295749568295666 FECH other 5.99331096507674e-22 1 1.03929880189987e-14 9.20009114309625 -2.1814950544337 2.21407959950072e-11 212.29900644961 38.8796280808147 5.46041762560918 7.28854877261401e-08 -260.082955874188 85.7880642762204 -3.03169162363629 0.00254990473622122 MYO9A other 1.97318773907504e-07 1 0.000750866294554695 5.46041762560918 -3.03169162363629 4.20467812613272e-27 927.176548445706 79.7908888950437 11.6200804538637 5.27018900983925e-28 984.471108017829 341.270521204498 2.8847235458345 0.00407460202187528 PFKP other 5.58717629400516e-23 1 7.67603029283087e-24 11.6200804538637 2.8847235458345 2.19352183015123e-05 382.160229037977 81.6978527351293 4.67772672406666 3.68480575239962e-06 284.440397185768 324.271265540891 0.877168060855828 0.380792037768132 IDI1 other 0.129001018831194 1 0.0342207910225353 4.67772672406666 0.877168060855828 1.57075166519459e-06 73.6992876325611 55.4588184485623 1.32890115033584 0.184438717356094 -494.737323367389 112.890956388571 -4.38243539778776 1.40924805777512e-05 SP100 other 0.0102962771653505 0.168574252671059 1 1.32890115033584 -4.38243539778776 0.0126344248666659 422.504503153587 153.138968945286 2.75896139345525 0.00599487986454122 -435.71832621959 660.232420967102 -0.659946879890197 0.509568774723212 KLF6 other 1 1 1 2.75896139345525 -0.659946879890197 7.90989840801439e-06 70.8116596179172 48.3623837244035 1.46418877988816 0.143723188504442 -408.240041913118 110.459076367655 -3.69584877347987 0.000241470308100814 PLPP1 other 0.0485193168347602 1 1 1.46418877988816 -3.69584877347987 1.94575045007069e-17 634.603182131769 79.8102515396806 7.9513993489452 1.08234366893687e-14 -368.944133034379 174.695050886616 -2.11193237107695 0.0351500356702166 NEO1 other 2.16270162525357e-13 1 1.37695761562148e-10 7.9513993489452 -2.11193237107695 2.74627368328864e-38 1106.83351573564 77.7481597577839 14.2361377964939 3.54242133032486e-39 109.617299635024 722.459833478847 0.151727880991232 0.879459302473357 TRAM1 other 3.99143417129172e-34 1 5.34586802959325e-35 14.2361377964939 0.151727880991232 1.00573892627067e-16 241.407236908326 40.0758747748869 6.02375464701276 3.18240593892789e-09 -758.307441202802 151.490919269506 -5.00562967641482 7.58192372648261e-07 TNFRSF1A other 1.09605428184977e-12 0.00968514936820889 3.47136839818254e-05 6.02375464701276 -5.00562967641482 9.38061844893752e-31 52.0938066551046 4.13169724196052 12.6083310572838 6.7821836115998e-32 62.4214968755085 32.6324853172545 1.91286370831531 0.056328548497926 CACNB1 other 1.29189877278767e-26 1 1.00335624350008e-27 12.6083310572838 1.91286370831531 8.62060628351147e-08 32.3010093113925 13.9963301500364 2.30781990458466 0.0213876738371567 -105.239453485431 26.8061226519212 -3.92594836828773 9.76124451024561e-05 EVI5 other 0.000626287046497109 1 1 2.30781990458466 -3.92594836828773 1.1288273945465e-18 104.278879645087 11.5289353671099 9.04497044389525 2.66112672263545e-18 -2.26219116067325 22.7956219998963 -0.0992379659867819 0.920986023442066 STOML1 other 1.29465213880538e-14 1 3.59012606150749e-14 9.04497044389525 -0.0992379659867819 9.60272543398254e-10 4817.35429260466 754.579670947699 6.38415594546087 3.74191163108033e-10 294.448002503621 1664.58257698992 0.176889994268757 0.859661742133557 PKM essential 7.8646321304317e-06 1 4.23546977521983e-06 6.38415594546087 0.176889994268757 1.01724430062599e-25 169.339755817576 37.944681700849 4.46280606996862 9.84404646248738e-06 -672.965907182083 87.9015783518773 -7.65590242860196 8.86368041887339e-14 DHX29 other 1.32709691459666e-21 1.31740882065715e-09 0.0887932990916362 4.46280606996862 -7.65590242860196 1.33821616304964e-57 387.41669489265 23.3798445481961 16.5705419509533 4.42109577854484e-50 -220.163820582656 71.0990118838401 -3.09658059583662 0.00206029270939615 DNTTIP2 essential 2.04947805371052e-53 1 6.77577139019782e-46 16.5705419509533 -3.09658059583662 3.86405422889223e-30 47.0269260397116 4.19115489629846 11.2205173044892 2.04510343239767e-26 -32.1731357478262 20.3410717633685 -1.58168340990594 0.11430520188746 METTL22 other 5.29143586104503e-26 1 2.95415190809843e-22 11.2205173044892 -1.58168340990594 9.93633679659347e-27 207.289260744477 78.109060443854 2.65384399154922 0.00819885954044165 -1141.76589057599 135.160571386218 -8.44747753628106 2.9237232200424e-16 TP53BP1 other 1.31417990471745e-22 4.42710169978821e-12 1 2.65384399154922 -8.44747753628106 1.67507102503891e-28 137.733972342435 11.5033473705027 11.973381999714 2.03300399894721e-29 13.4726092912011 71.1717587758454 0.189297124631034 0.849932145324748 RRP15 essential 2.25933579857248e-24 1 2.9807904632564e-25 11.973381999714 0.189297124631034 9.09947324768425e-34 1336.46657843348 277.115763887703 4.82277355746192 1.86032591109308e-06 -4311.06254236874 501.510775310771 -8.59615137819781 9.62565854945742e-17 RHOA other 1.28675651195503e-29 1.4618487639061e-12 0.0176098450744071 4.82277355746192 -8.59615137819781 2.28576706367971e-49 342.605569279651 30.8751084969241 11.0964976629566 6.68525795931374e-26 -475.173967974823 68.6983866500499 -6.91681407884238 1.31803782878671e-11 DHX8 essential 3.45013680591815e-45 1.91089124417497e-07 9.62342883243213e-22 11.0964976629566 -6.91681407884238 3.01445066952347e-18 106.901096471145 21.3733709533518 5.00160207318072 7.69643582078604e-07 -221.142350272928 43.5067270016098 -5.08294614450646 5.12777295122273e-07 PRKCZ other 3.42321018031085e-14 0.00659585434715779 0.00745784631034167 5.00160207318072 -5.08294614450646 1.27562574044557e-24 821.256158716724 75.6989679127232 10.8489743171081 6.56107015615435e-25 -499.48500002655 477.973069804719 -1.04500657376078 0.296494516405838 IARS2 essential 1.63943420162064e-20 1 9.39479635659742e-21 10.8489743171081 -1.04500657376078 0.0570647336354491 10.3590477795459 112.121092554587 0.0923916057498506 0.926421689054469 -932.28947907858 400.492366887957 -2.32785829683341 0.0202937018134804 SYT1 other 1 1 1 0.0923916057498506 -2.32785829683341 0.0873823214270022 -84.2762331924099 66.8187020561665 -1.2612671392744 0.207769583947295 -499.450694718789 247.117723096211 -2.02110430794288 0.0437730809919574 NAV3 other 1 1 1 -1.2612671392744 -2.02110430794288 3.89756453870095e-21 235.173989183501 30.2002648149571 7.78714990164683 3.50497155160359e-14 -644.853260106235 153.883588179567 -4.190526538501 3.24925154925379e-05 ROGDI other 4.72228919509007e-17 0.379187655797917 4.4120581891586e-10 7.78714990164683 -4.190526538501 8.57813676747406e-08 272.417355694903 70.0453801530651 3.88915521765475 0.000114098503659711 -397.392035283534 158.158286673714 -2.51262228265893 0.0122955005767334 ROCK1 other 0.00062337319889234 1 0.937205109060868 3.88915521765475 -2.51262228265893 1.45062641281959e-44 324.344634503729 34.9974570303216 9.26766291112861 4.73090683137342e-19 -363.274032896112 76.8994444571817 -4.72401374886897 2.96419255149369e-06 CBFB other 2.16288398151401e-40 0.0368330566448606 6.43734492544981e-15 9.26766291112861 -4.72401374886897 1.03669814245388e-07 92.6262496790852 41.7857092784955 2.2166968391453 0.0270715810166173 -276.124425232093 76.8487458128871 -3.59308954637212 0.000357536563753169 HYAL2 other 0.000749221747551422 1 1 2.2166968391453 -3.59308954637212 0.00308542033280429 25.3599906819928 17.4960177708461 1.44947216070222 0.147778833599948 -79.6163046427358 33.8050079036215 -2.35516302406208 0.0188667953093666 HDAC4 other 1 1 1 1.44947216070222 -2.35516302406208 7.2134248894662e-10 52.0583949350639 23.8410564213834 2.18356074558727 0.0294365064511 -194.167115554836 43.8464565152299 -4.42834224214658 1.15601062350752e-05 RASSF1 other 5.95107553380962e-06 0.138998717370544 1 2.18356074558727 -4.42834224214658 3.20236569007091e-06 354.368387082015 112.863043304493 3.13980889320842 0.00178428246741434 -538.247090661266 247.741499581853 -2.17261577721028 0.0302491376396563 FGFR3 og 0.0203990694457517 1 1 3.13980889320842 -2.17261577721028 3.52929266610146e-14 269.811266058442 51.8359857436401 5.20509569149162 2.76860541960165e-07 -411.238521070871 114.254409050584 -3.59932298882929 0.000348696295324896 IFI35 other 3.53352781730078e-10 1 0.00275836157954912 5.20509569149162 -3.59932298882929 5.48916321068034e-73 221.702146644383 10.8974085374669 20.3444833587855 1.87988268936124e-67 -150.351197940992 43.498751718879 -3.45644856460874 0.000594072148390871 HEATR6 other 8.50930080919667e-69 1 2.91438213331673e-63 20.3444833587855 -3.45644856460874 9.46294366978257e-47 369.415705989912 48.0523274801217 7.68777966359138 7.19925867357552e-14 -1074.8170305383 106.855957208459 -10.0585597529346 6.41896963344053e-22 COASY essential 1.4189684032839e-42 9.940416374346e-18 8.99547371263261e-10 7.68777966359138 -10.0585597529346 3.59857956745792e-21 120.807252820114 36.5497771671107 3.30528014624457 0.00101240426731772 -614.332576209311 81.6767442774369 -7.52151155930709 2.30302455298343e-13 PLEKHH3 other 4.36327772554273e-17 3.40640361631779e-09 1 3.30528014624457 -7.52151155930709 1.17980104011679e-21 468.914760787203 45.852614630855 10.2265653673687 1.43787801998886e-22 214.346894219245 141.743177511128 1.51222018571171 0.131059614134544 MEF2A other 1.44322343071934e-17 1 2.02223164731233e-18 10.2265653673687 1.51222018571171 1.26601360145632e-15 78.3432445078594 15.355081368377 5.10210546127115 4.67847276293524e-07 -130.952297339286 30.5432785800677 -4.28743420572878 2.14578366838622e-05 INPP5A other 1.33425173457481e-11 0.253781834460038 0.00459753518413646 5.10210546127115 -4.28743420572878 1.84360482348489e-30 122.488029475725 14.3713712988056 8.52305788563855 1.79787870324611e-16 599.373019847949 56.0742954221394 10.6889086226718 3.49535093043571e-24 PRR11 other 2.53237558553884e-26 5.43527069682752e-20 2.35899664652922e-12 8.52305788563855 10.6889086226718 0.0393833353753515 -59.2332140285476 39.3825860605312 -1.50404582211808 0.133152031075012 -325.898092553131 143.151225918972 -2.27660008121481 0.0231991483482438 REEP1 other 1 1 1 -1.50404582211808 -2.27660008121481 1.77263301604114e-50 470.185614631142 28.1557883131166 16.6994299503276 7.0357049529564e-51 532.101502302076 80.6914121113236 6.59427674370077 1.01019981434896e-10 ATP11A other 2.6842981761911e-46 1.44408063461184e-06 1.07920678273398e-46 16.6994299503276 6.59427674370077 1.18192691376086e-08 221.936797730549 41.9187251902125 5.29445484621675 1.73729531804276e-07 -365.009355111836 152.131481317729 -2.39930191930169 0.0167630091915602 POLR1A essential 9.09965530904487e-05 1 0.00174963011480086 5.29445484621675 -2.39930191930169 8.15816795331071e-08 409.214884949767 181.415149910218 2.25568198219546 0.0244877299630755 -2414.9358019452 521.667521848417 -4.6292623190119 4.5959171044125e-06 LAPTM4A other 0.000593506718603354 0.0565619518040047 1 2.25568198219546 -4.6292623190119 1.32744364866679e-15 275.559897826168 32.3475632949625 8.51872196101651 1.58759686773441e-16 209.13037354287 111.522312560864 1.87523347337992 0.0612960502645928 TTC7A other 1.39779816204612e-11 1 2.08530848576914e-12 8.51872196101651 1.87523347337992 3.92550664968174e-31 123.221442081928 43.6580228306484 2.82242378588489 0.0049469593576555 -753.348124406534 78.9614391037432 -9.54070914812926 5.30238744803657e-20 IP6K2 other 5.43054589916972e-27 8.16673714746592e-16 1 2.82242378588489 -9.54070914812926 0.000270706979973148 31.0413691915853 7.66341396896603 4.05059276678661 5.85065157268698e-05 30.6453673843519 27.2792734545118 1.12339382628548 0.261764872998097 STON1-GTF2A1L other 1 1 0.493853499250508 4.05059276678661 1.12339382628548 9.11612286317131e-08 53.0502985759294 12.7537907135544 4.15957104577143 3.70471181392884e-05 -143.933421281851 43.4894380164086 -3.30961787152882 0.000996097590305887 SRBD1 essential 0.000660736585122657 1 0.318568168879741 4.15957104577143 -3.30961787152882 0.00130952103868584 87.2554620715373 25.4864760735727 3.42359853200787 0.000664888060632381 14.2059708604461 58.3222108215611 0.243577372330926 0.807650659946101 KIF2A other 1 1 1 3.42359853200787 0.243577372330926 0.0378279710694909 -8.40339249513971 5.06558850470745 -1.65891731776682 0.0977207347623597 -29.0909705488233 11.8502031650303 -2.45489213507075 0.014411150689698 RASGRP2 other 1 1 1 -1.65891731776682 -2.45489213507075 9.91768376421697e-19 1151.69102804526 121.92007195022 9.44627910419458 1.04088608105457e-19 881.97176569484 434.361063041252 2.03050374616814 0.0427930643441937 PSME4 other 1.1392443339956e-14 1 1.4267425513015e-15 9.44627910419458 2.03050374616814 5.96589627263726e-09 83.3026848438258 13.4488283679765 6.19404773148722 1.16722394137268e-09 -34.7199186567787 50.6203831853563 -0.685888104197968 0.493079678275901 IFT80 other 4.67845585700214e-05 1 1.29608546450023e-05 6.19404773148722 -0.685888104197968 1.25982867010961e-50 287.574760706394 17.924642287634 16.0435425204991 1.03628425067838e-47 -158.475372659401 95.4266701549291 -1.66070315984106 0.0973492887059178 SIRT2 other 1.90838846948203e-46 1 1.58344233503656e-43 16.0435425204991 -1.66070315984106 0.00379230402424716 101.78868211918 51.037083247732 1.99440633441181 0.0466081039674684 -429.746465523197 181.828318991324 -2.36347378619115 0.0184564289787487 ERLEC1 other 1 1 1 1.99440633441181 -2.36347378619115 5.3299953567278e-13 51.0846567252592 11.3320883244103 4.50796492780755 8.08088104361959e-06 -107.684030942906 26.8860084979104 -4.00520705597765 7.09253397956195e-05 PPP2R5B other 5.08374957124698e-09 0.808619799009858 0.0733259145898041 4.50796492780755 -4.00520705597765 0.764772720270616 262.60216454695 501.163524377869 0.523984990473792 0.6005072013946 -309.088375286418 1172.17280604065 -0.263688403018369 0.792122137346255 PYGM other 1 1 1 0.523984990473792 -0.263688403018369 0.0768396825884268 140.837496960107 71.998252965012 1.95612381078951 0.0509619031275766 -59.6942339946662 166.830175921809 -0.357814368203054 0.720621023906983 PITX1 other 1 1 1 1.95612381078951 -0.357814368203054 1.38429957558454e-12 -21.1841582108011 119.898291900854 -0.176684403713764 0.85982303139278 -1842.91788316442 264.240788477799 -6.97438837425834 9.08310769635215e-12 MAST4 other 1.30124160104947e-08 1.31923056181819e-07 1 -0.176684403713764 -6.97438837425834 0.823277530321974 1.7477440739779 28.3321525647402 0.0616876557467431 0.950834227530664 -77.2189460210141 132.340664903685 -0.583486157313873 0.559807898017708 ADGRF5 other 1 1 1 0.0616876557467431 -0.583486157313873 0.0101473127695469 66.2526500547974 22.3921718190365 2.95874159015131 0.0032277909111601 -8.4303203058574 74.7648297947132 -0.11275783451932 0.910265485885605 SDK2 other 1 1 1 2.95874159015131 -0.11275783451932 6.25086091403202e-24 311.113142553373 29.5808665958398 10.5173775604373 1.14297732395202e-23 -338.018800141588 176.853896977392 -1.91128839069233 0.0564946663616045 NUP133 essential 7.9454693078261e-20 1 1.62302780001187e-19 10.5173775604373 -1.91128839069233 3.9891026865793e-37 2048.68965785909 149.827775304427 13.6736306315465 9.23185894489218e-37 3536.46251522134 1369.69694607198 2.58193064193011 0.0100872271628846 NUCKS1 other 5.76106209995782e-33 1 1.38514811609162e-32 13.6736306315465 2.58193064193011 7.03932941160551e-44 492.696753233128 79.840428674178 6.17101838523165 1.45064619194401e-09 -1801.34469215466 209.243932514981 -8.60882640898412 1.07999630574982e-16 VPS35 essential 1.04717064327044e-39 1.63997439028111e-12 1.6036893651941e-05 6.17101838523165 -8.60882640898412 6.88272268953502e-63 242.456391201669 30.6648655923836 7.90665103263615 1.81751517791535e-14 -870.091221165244 81.264592509608 -10.7068920706441 3.82627858694605e-24 DNAJA2 other 1.06055873923045e-58 5.94871531912503e-20 2.30061071220525e-10 7.90665103263615 -10.7068920706441 0.0244546742877242 49.7017191412262 20.7433664497344 2.39602955777039 0.0169111658582931 -0.418121035851584 34.5312465894872 -0.012108483682106 0.990343511242571 KCNAB2 other 1 1 1 2.39602955777039 -0.012108483682106 0.343702711200619 16.2768852365048 17.8766346934623 0.910511710711272 0.362968965841027 -52.172903534592 63.0002406601744 -0.828138162455831 0.407967129311771 ABCC9 other 1 1 1 0.910511710711272 -0.828138162455831 0.207476063071342 10.3370504363205 9.01715890141217 1.14637554348761 0.252193649551958 68.2442946960048 43.595107787421 1.56541176658579 0.118125426995937 GAL other 1 1 1 1.14637554348761 1.56541176658579 0.000323942488438539 45.1199829420437 14.5186980743396 3.10771549287803 0.00198407114277577 -69.6430601378034 47.0597417234477 -1.47988615294723 0.139483559732995 CLEC2D other 1 1 1 3.10771549287803 -1.47988615294723 2.61313132197109e-13 144.953668227894 19.9526369568842 7.26488777103128 1.31009372591524e-12 -15.970313941636 40.805854862062 -0.391373100640122 0.695675569085089 RORA other 2.53029505906461e-09 1 1.58861965204482e-08 7.26488777103128 -0.391373100640122 0.0165973965302075 -2.00061797676551 1.51005271571001 -1.32486631489871 0.18577378185588 -8.87315887575382 3.0980106872132 -2.86414727759885 0.00434336761309346 DRD4 other 1 1 1 -1.32486631489871 -2.86414727759885 0.00738957211865243 73.997617058192 166.828634219479 0.44355465357848 0.657543250577165 -859.227908336567 320.544733691239 -2.68052417658563 0.0075765461543742 TGFBR3 other 1 1 1 0.44355465357848 -2.68052417658563 0.0148407602825284 8.92407323958323 8.21823623841221 1.08588667698209 0.278015436805522 -31.9038626887829 15.6479095708044 -2.03885781320647 0.0419524980869762 KIAA1107 other 1 1 1 1.08588667698209 -2.03885781320647 0.0297941039878423 4.87234590887551 3.54814671117833 1.37320869329482 0.17025111910051 -33.8444368901077 18.5946376776687 -1.8201181155981 0.0692883800958361 PLA2G10 other 1 1 1 1.37320869329482 -1.8201181155981 0.000951425287047741 83.7958365202526 27.2544368722828 3.07457596401382 0.00221441477440795 -15.8551281208426 44.3248660639739 -0.357702786917821 0.720705255499012 HES2 other 1 1 1 3.07457596401382 -0.357702786917821 0.000317981877640715 489.734645821654 123.802960633274 3.95575875824436 8.6369970996742e-05 -152.986531069028 446.809175972993 -0.342397916819583 0.732183461697312 ATP1B3 other 1 1 0.717993568895917 3.95575875824436 -0.342397916819583 4.45900487040894e-15 29.9960456995607 24.5015163703048 1.22425262364231 0.221389798558484 -326.852031322061 45.9331551042704 -7.11581929393033 3.54890922279671e-12 NEDD4 other 4.61373233941214e-11 5.1814074652832e-08 1 1.22425262364231 -7.11581929393033 1.15224931481929e-31 34.4982749917379 10.8581872935517 3.17716705920383 0.00157193336802955 -204.424412074816 20.3002245656845 -10.0700566840219 5.57337910134859e-22 PIGB other 1.60105042294141e-27 8.63316422798896e-18 1 3.17716705920383 -10.0700566840219 1.88350836377519e-07 219.948425920026 40.4344000235547 5.439636195712 8.10482700273237e-08 49.2126387654432 88.7679304599678 0.554396599204675 0.579536976932011 MAPK6 other 0.00133607574333549 1 0.000832689926260723 5.439636195712 0.554396599204675 4.718557810645e-08 72.5147280707515 21.1080386830948 3.43540814755224 0.000637256413989212 -147.367022411356 46.2063116384383 -3.18932667823597 0.00150892331202289 GNB5 other 0.000349692319346901 1 1 3.43540814755224 -3.18932667823597 0.0672330243196231 48.349254251691 34.4794516575534 1.40226285301435 0.161409239441879 -73.8910168832918 64.4620130991541 -1.14627225137437 0.252188331195096 RAB27A other 1 1 1 1.40226285301435 -1.14627225137437 5.17289326273544e-27 211.752203591946 27.1773235292312 7.79150321274983 3.44659761022789e-14 -165.243121271857 51.5879235056386 -3.20313573493215 0.0014400022090305 HDHD5 other 6.86442935964993e-23 1 4.33961105103794e-10 7.79150321274983 -3.20313573493215 2.14236960111446e-38 311.746325249412 32.752476113808 9.51825212134064 5.8963572586066e-20 -263.993071903881 64.6957792395109 -4.0805300594116 5.17455499002168e-05 UFD1 other 3.11500540002042e-34 0.596367462599999 8.10395341622892e-16 9.51825212134064 -4.0805300594116 1.39530228465801e-27 708.42949351987 61.9800961041479 11.4299515174914 2.99346307610463e-27 178.502585243639 200.377683823434 0.890830664561078 0.373416017508266 LRP6 other 1.8637052616177e-23 1 4.34171884558215e-23 11.4299515174914 0.890830664561078 6.58918090198989e-05 4.03406579061004 1.20407566364391 3.35034243479492 0.000863316650597294 -6.19569762109105 3.78146602997278 -1.63843799520675 0.101910693999673 GUCY2C other 0.366951484431817 1 1 3.35034243479492 -1.63843799520675 6.55847667717659e-23 145.413204858194 37.8991224458806 3.8368488628158 0.00013937894575067 -496.880927068861 77.9313852387827 -6.37587700444964 3.91327113992699e-10 PHRF1 other 8.20596601848335e-19 5.53219141051478e-06 1 3.8368488628158 -6.37587700444964 8.01190364346066e-17 902.839707416165 101.424684265485 8.90157769732787 8.19442173772578e-18 18.6251343837687 401.177961408015 0.0464261155283805 0.962987659445508 PFN2 other 8.75620949193815e-13 1 1.09919973189854e-13 8.90157769732787 0.0464261155283805 1.42579862844477e-09 96.7217898331572 36.8254997110035 2.62648954100293 0.00886882635073757 -370.133754593531 77.9655210340903 -4.74740307874927 2.63463719554494e-06 PTPN3 other 1.15831880574853e-05 0.0328223101820988 1 2.62648954100293 -4.74740307874927 4.95264926769323e-07 147.4323659095 28.3870342638267 5.19365159950404 2.91730834083638e-07 227.990364074768 63.8978706906583 3.56804321662786 0.000391360652999562 DAPP1 other 0.00339306001329663 1 0.00290359699163445 5.19365159950404 3.56804321662786 0.325252703518705 -97.5977833221674 65.3621318928785 -1.49318543468135 0.13600221265937 -113.777082654758 309.583582076006 -0.367516526205269 0.713385042243747 FGF10 other 1 1 1 -1.49318543468135 -0.367516526205269 4.77623256868941e-13 -48.5973949926727 159.419836992939 -0.304839070904489 0.76060467207771 -2489.56066730041 338.917584275294 -7.34562260209608 7.48331179721481e-13 SLC44A1 other 4.56607833566708e-09 1.10072033225233e-08 1 -0.304839070904489 -7.34562260209608 5.77589924251005e-15 41.9803887812789 13.9441275052227 3.01061423639131 0.00272888366431347 -189.008213029212 30.3760402217287 -6.22227952193748 9.82274568060047e-10 TMEM260 other 5.95552970895211e-11 1.37646135222254e-05 1 3.01061423639131 -6.22227952193748 9.39635853808158e-50 108.51948263266 26.4799512520495 4.0981753176098 4.80162086505e-05 -630.719382440944 48.6742432332033 -12.9579699764227 1.21100695176466e-33 SMG6 essential 1.41997770227489e-45 1.89704238993934e-29 0.408281822155201 4.0981753176098 -12.9579699764227 5.06957117972844e-14 250.833548690555 39.6686933426219 6.32321177115877 5.36681120536437e-10 -211.587539505753 86.6363305077381 -2.44224955357331 0.0149151102275919 EXOC5 essential 5.04270245247588e-10 1 6.0360525626733e-06 6.32321177115877 -2.44224955357331 0.000686681558224489 43.7468842767769 12.9432857507509 3.37989017002418 0.000777754520100045 6.104274003279 25.4079756436437 0.240250309150705 0.81022772966334 CLTCL1 other 1 1 1 3.37989017002418 0.240250309150705 2.45750973278533e-06 18.6206642557342 48.9093409560742 0.380717954724794 0.703567428380798 -377.787201435479 87.8674275877524 -4.29951361735481 2.04310926177761e-05 FSTL3 other 0.0158397815877703 0.242088016428029 1 0.380717954724794 -4.29951361735481 2.44086273246813e-44 333.607968065126 72.9266483978816 4.57456876730424 5.92684166474158e-06 -1463.88983232605 143.081721331824 -10.231144961774 1.42424524406233e-22 DGCR2 other 3.63615321255778e-40 2.20928922258949e-18 0.0543076501740271 4.57456876730424 -10.231144961774 5.99293495936202e-08 46.4754058060273 25.1200339477742 1.85013308113564 0.0648592771111929 -178.691072465286 45.1290637076926 -3.95955638749108 8.55049649165864e-05 RNF126 other 0.000441139942358639 0.96860024257509 1 1.85013308113564 -3.95955638749108 6.34892944450359e-23 62.4012856117999 18.2446265874384 3.42025556471317 0.000673115930916465 -256.313274861953 33.5735616647112 -7.63437842614598 1.04172624308583e-13 MNT other 7.94695498568515e-19 1.54685929835815e-09 1 3.42025556471317 -7.63437842614598 4.33330684259186e-20 120.445364155978 14.5431215846503 8.28194713596449 9.45933645531619e-16 -159.113902055285 46.4129204092354 -3.42822431022082 0.000653551108163554 ZXDC other 5.14060190736672e-16 1 1.225078664328e-11 8.28194713596449 -3.42822431022082 3.0289512274515e-50 170.147014912215 10.1031357257666 16.8410105070922 1.77267448335895e-51 113.283624401371 32.0037440135605 3.53969911624626 0.000435083316052509 JMJD6 essential 4.58340899737961e-46 1 2.72070079705932e-47 16.8410105070922 3.53969911624626 5.4653831014122e-28 160.360362010148 18.7532582485755 8.55106669382795 2.51388101654345e-16 -452.344542840471 82.9600971432361 -5.45255560705851 8.63966119615943e-08 POLB other 7.33126489223433e-24 0.00114613745428251 3.29041886255372e-12 8.55106669382795 -5.45255560705851 0.945786385139832 0.980989030192754 5.51562845249908 0.177856256751355 0.858902439186683 -4.10890767494782 17.2952312245756 -0.237574602015687 0.812300994218148 ST6GALNAC1 other 1 1 1 0.177856256751355 -0.237574602015687 1.76616901553446e-18 153.081228285932 18.7233742577889 8.17594233700961 2.21030387514917e-15 -305.842890283533 94.4979488647035 -3.23650295014785 0.00128623482412515 WIPI1 other 2.01714163264191e-14 1 2.84510314809201e-11 8.17594233700961 -3.23650295014785 0.0287432126803141 5.50811269042988 2.74325603517021 2.00787408095071 0.0451589260385928 15.6758408036502 6.84246889837552 2.29096266807612 0.0223535088654186 FRMPD1 other 1 1 1 2.00787408095071 2.29096266807612 2.19886922085711e-24 139.72488937095 24.5627297416243 5.68849190789128 2.12731281983742e-08 -481.030189890183 66.0722443764986 -7.28036703504629 1.21803831793096e-12 GBA2 other 2.81587192422962e-20 1.78795844689086e-08 0.000224686780031228 5.68849190789128 -7.28036703504629 3.02123449222946e-10 9.42099404699772 138.22200876309 0.0681584223185841 0.945684568193075 -2074.92393621443 327.910627735907 -6.32771176262557 5.20279774381834e-10 NDST1 other 2.5450879362541e-06 7.33438397946071e-06 1 0.0681584223185841 -6.32771176262557 6.13800511102941e-07 244.700455140872 51.3276619666932 4.76741869325081 2.40192618148586e-06 -177.892648179807 157.977240909288 -1.12606504048234 0.260637256720571 ASNS other 0.0041738434755 1 0.0226069292201449 4.76741869325081 -1.12606504048234 3.90725694503064e-30 179.691368587852 16.4297672893019 10.9369393627904 1.37015043320423e-24 -183.172857975937 72.1600381442825 -2.53842518222741 0.0115060904671789 AP3M2 other 5.35020693483045e-26 1 1.95712287878892e-20 10.9369393627904 -2.53842518222741 2.19009166511969e-10 309.8335737724 63.3668926415568 4.8895181830205 1.33461148543032e-06 -710.303227446703 199.541851787847 -3.55967042042839 0.000404002579679326 ST6GALNAC2 other 1.86135890618523e-06 1 0.0127522127432868 4.8895181830205 -3.55967042042839 0.122831985212376 -10.0133831754263 26.3551046002346 -0.379940938475243 0.704137543209291 -111.085283320868 55.1058441113781 -2.01585303904149 0.0443064779323837 TESK2 other 1 1 1 -0.379940938475243 -2.01585303904149 3.00310394551809e-66 177.839265278067 14.1441537956642 12.5733407489236 5.23888683022406e-32 -153.201373936029 30.7503199727199 -4.98210666009138 8.46264965183793e-07 CFAP20 other 4.63829404385269e-62 0.0107848007163023 7.75407639741464e-28 12.5733407489236 -4.98210666009138 4.40443892707058e-64 421.369847415898 35.4095147527327 11.8999045979126 3.49736076847789e-29 -413.202125426091 76.9826123538799 -5.36747341759007 1.18396642434422e-07 CSNK2A2 other 6.79516837668449e-60 0.00156295407677681 5.12118537328217e-25 11.8999045979126 -5.36747341759007 2.11576480191629e-05 -1.79069021516937 23.2113030925603 -0.0771473367104206 0.938534753394128 -201.056927321191 46.8033351329745 -4.29578205805123 2.06277106027465e-05 PTPN21 other 0.124703177424946 0.244273348957724 1 -0.0771473367104206 -4.29578205805123 6.3531924060633e-20 139.605850444364 18.563250826345 7.52054970060715 2.26698927781174e-13 -141.274571756706 39.9731420126734 -3.5342373564709 0.000443767018158575 EIF2B3 essential 7.51265002016986e-16 1 2.80063855380862e-09 7.52054970060715 -3.5342373564709 0.251102040933091 23.8877906003543 14.8305566165666 1.61071436615334 0.107824175235633 5.51343684530005 35.185996405006 0.156694066066455 0.875544312984056 CAMK2A other 1 1 1 1.61071436615334 0.156694066066455 5.27053963128771e-09 200.655613442998 40.9535101866118 4.89959499268013 1.27008030706766e-06 522.258189686061 97.163585929663 5.37504029610563 1.1393203454557e-07 TCOF1 other 4.14633352793404e-05 0.00150470038024334 0.0121521283780234 4.89959499268013 5.37504029610563 5.34167120237826e-25 523.353726822852 142.847378998804 3.66372649250522 0.000272806907035276 -1690.48959822805 237.602921435979 -7.1147677310169 3.53813122624504e-12 CDC42 essential 6.90143919347271e-21 5.16602540344038e-08 1 3.66372649250522 -7.1147677310169 0.0385236431152954 39.5229740808377 16.6995581069995 2.36670777918799 0.0182995943166431 129.589370821285 91.6018482777095 1.4147025770529 0.157733139706297 OSBPL3 other 1 1 1 2.36670777918799 1.4147025770529 0.404234985379999 -0.147567514845333 5.49757546908839 -0.0268422899649257 0.97859533046331 -10.0174794740451 8.65097538349489 -1.1579595398176 0.24738681391685 EPHA8 other 1 1 1 -0.0268422899649257 -1.1579595398176 0.0874861335727641 9.14187952838788 12.0341867564403 0.759659103968568 0.447786841108743 -29.7876120937807 25.5651575377669 -1.16516442544021 0.244462157818426 SLC12A3 other 1 1 1 0.759659103968568 -1.16516442544021 2.07603191523627e-13 123.901728262354 15.8312749893552 7.82638974723544 2.6803864135127e-14 32.0058426964652 40.9016215081454 0.782507918178534 0.434260410037688 RAD18 other 2.01790302160966e-09 1 3.38020288750639e-10 7.82638974723544 0.782507918178534 0.000179348470249496 110.572604646581 43.4019055564114 2.54764400846097 0.0111265500007962 -295.045708146991 116.030546479807 -2.54282787678103 0.0112791647999469 ATP2B1 other 0.942296862690853 1 1 2.54764400846097 -2.54282787678103 5.87946522167146e-05 204.006430854353 45.8509859230644 4.44933575030787 1.04406400314404e-05 91.7552697311274 143.838318029334 0.637905608103781 0.523802068513273 NCK2 other 0.329250052413602 1 0.093934438362869 4.44933575030787 0.637905608103781 6.05392584573054e-06 419.891636398577 87.0194747361282 4.82526052555279 1.81770403647999e-06 -109.285681176132 327.591607960994 -0.333603421212012 0.738807148019144 MAP4K4 other 0.0374677470592263 1 0.0172118395214291 4.82526052555279 -0.333603421212012 0.00511058066953627 -64.6343387202903 158.792204390909 -0.407037228107091 0.684140456359729 -1782.84985993666 547.075038398643 -3.25887626888496 0.00118827156200902 MGAT4A other 1 1 1 -0.407037228107091 -3.25887626888496 0.000474500445846052 350.354518255027 347.255391836577 1.00892463152857 0.31345850196724 -3836.09470820844 1091.24486451463 -3.51533815457146 0.000475748433663883 RPL31 essential 1 1 1 1.00892463152857 -3.51533815457146 5.36285661863633e-34 1432.81752515817 144.99319075947 9.88196423330718 2.76292182702922e-21 -1184.12734908874 318.160474769499 -3.72179275237322 0.000218475860227088 WDR1 essential 7.59380497198904e-30 1 3.84239538484954e-17 9.88196423330718 -3.72179275237322 1.82127448390308e-07 51.2256888743226 30.1083728943665 1.70137685799379 0.0894489596093855 -525.424491350058 110.476223370796 -4.75599613490184 2.53832557749522e-06 SNX13 other 0.00129328701101957 0.0316554582769429 1 1.70137685799379 -4.75599613490184 0.041941776498292 36.574617257281 16.0712880688795 2.27577385835701 0.0232503756300239 -6.79695298279148 36.9468393255111 -0.183965749354325 0.854109384232717 ARHGAP10 other 1 1 1 2.27577385835701 -0.183965749354325 1.56290963635601e-06 -64.0541126061134 32.9012960065781 -1.94685682270105 0.052064312168406 -358.449497550676 68.9960177093329 -5.19522009314734 2.89218787866564e-07 RPS6KA2 other 0.01024643557595 0.00375377064772014 1 -1.94685682270105 -5.19522009314734 1.25610481058079e-06 27.2856400547658 7.74334383642073 3.52375415985379 0.000461219079900628 -63.4035252704173 24.2027624493884 -2.61968134435082 0.00904644779314566 ING3 essential 0.00830913332199194 1 1 3.52375415985379 -2.61968134435082 7.0994922556769e-06 -40.9780618758154 34.557733594697 -1.18578557136929 0.236223715095655 -349.460362013293 72.3582952903523 -4.82958257392622 1.78028020875255e-06 VASH1 other 0.0437115738182027 0.022346077180262 1 -1.18578557136929 -4.82958257392622 0.0560525451263648 -22.9751535586106 60.7574100308649 -0.37814570349426 0.705471512722609 -368.773534685757 153.242039067508 -2.40647760190206 0.0164432760113813 LMCD1 other 1 1 1 -0.37814570349426 -2.40647760190206 1.29086300158157e-22 454.722780412921 51.9985665936472 8.74490991196815 2.96307893951579e-17 -731.575190911055 195.196853701253 -3.74788413357689 0.000197925478874393 BUD23 other 1.60764078216968e-18 1 3.93970975798019e-13 8.74490991196815 -3.74788413357689 1.24214567688469e-17 173.597814488461 146.624651798321 1.18396062571553 0.236948580004508 -2351.9121518915 305.684160837233 -7.69392874478642 6.80119763386003e-14 SEL1L other 1.3884704376217e-13 1.01167814803668e-09 1 1.18396062571553 -7.69392874478642 3.65753283988909e-23 230.847586049746 21.7864446043723 10.5959274329423 6.74493353129313e-24 292.692981628683 99.7784392799979 2.93342914301685 0.00349946942557675 TRIP13 other 4.59532426003665e-19 1 9.5953424416176e-20 10.5959274329423 2.93342914301685 0.00104311961462786 277.423258395443 103.173648742859 2.68889645540083 0.00739851708952439 -182.75945101367 185.218584156204 -0.986723075582632 0.324236425176728 TCF3 other 1 1 1 2.68889645540083 -0.986723075582632 1.71656703753831e-06 446.284398066009 87.0806020772532 5.12495765325658 4.14617051583178e-07 97.3982297089993 256.937692859603 0.37907334118634 0.704781858563383 TRIB2 other 0.0112263484255005 1 0.00409102644797122 5.12495765325658 0.37907334118634 0.0108785784681868 199.997468411414 66.3003334074001 3.01653789857249 0.00267999626535114 187.90451916787 118.725592347565 1.58267914652964 0.114093389608805 DAZAP1 other 1 1 1 3.01653789857249 1.58267914652964 5.87605066891871e-06 136.002444838241 85.01118003999 1.59981833888513 0.110243920077764 -512.602321320636 152.207023622622 -3.36779676207038 0.000813635272146107 MBD3 other 0.0364138859952893 1 1 1.59981833888513 -3.36779676207038 5.87838257807863e-14 427.046048718668 56.8513361860389 7.51162729616791 2.41739060543868e-13 -526.333847039072 221.591513559724 -2.37524370217911 0.0178836215071072 HLTF other 5.83429470874304e-10 1 2.9845104414746e-09 7.51162729616791 -2.37524370217911 0.724273877489837 0.117251837988609 61.6752930056189 0.00190111521607083 0.998483829937547 -124.397788801508 161.348286983224 -0.770989213008764 0.441049288528463 MYO3B other 1 1 1 0.00190111521607083 -0.770989213008764 5.02762322484561e-07 -2113.63328475606 604.06881154004 -3.49899422777261 0.000505557821642292 -7499.79387746345 1496.65736251696 -5.01102928785979 7.34872182959926e-07 CYBRD1 other 0.00344191085972931 0.00939166649822785 1 -3.49899422777261 -5.01102928785979 0.0679784642095125 71.5540369639389 30.9703193066825 2.3104068206523 0.0212451689519886 77.8332480817838 63.3924271863695 1.22780040986535 0.220061819556247 CDH19 other 1 1 1 2.3104068206523 1.22780040986535 1.11848763144537e-43 254.535248346252 26.127197257649 9.74215664375307 9.13400803890569e-21 -296.157558924495 52.4696136672269 -5.64436324617877 2.68296933993481e-08 PDCD2 essential 1.66274371290669e-39 0.000361825245183608 1.26515145346883e-16 9.74215664375307 -5.64436324617877 0.00322551688737907 16.4784919629122 23.0273560568809 0.715605036123469 0.474549214948407 193.459429077599 56.9480886871907 3.39711891193135 0.000731946061911122 SLC6A15 other 1 1 1 0.715605036123469 3.39711891193135 6.42756249516225e-20 286.764937717126 57.5453231983727 4.98328833306883 8.44504335517899e-07 -587.770766191999 110.332164591083 -5.32728391915824 1.46896863017905e-07 RDH11 other 7.59930713803033e-16 0.00193037167691828 0.00816382341145153 4.98328833306883 -5.32728391915824 3.18555578677904e-35 518.07472205698 44.8041265566804 11.5631028182545 9.40514899115858e-28 -582.160252731324 156.385580415621 -3.72259546682075 0.000218118934232435 PRKACA other 4.55152210814989e-31 1 1.36844917821357e-23 11.5631028182545 -3.72259546682075 2.53508123755813e-14 378.944799174322 50.8716980415913 7.44902988818079 3.79537153876398e-13 -194.184941357247 180.451519059389 -1.07610588356055 0.282364929728779 ADGRL1 other 2.55054523310723e-10 1 4.66033671244829e-09 7.44902988818079 -1.07610588356055 0.182451625370545 508.074123658696 328.050207096025 1.54876940379427 0.122029583264163 -128.056844925255 643.22950231444 -0.199084221828268 0.842272641663453 ACTN1 other 1 1 1 1.54876940379427 -0.199084221828268 1.75246195170238e-07 37.1766159377531 54.9750290414946 0.676245498837164 0.499176477041438 -498.169434914115 105.361975724995 -4.72817096951926 2.89999283905171e-06 ZFYVE26 other 0.00124617569385556 0.0360527109750909 1 0.676245498837164 -4.72817096951926 2.89573012671781e-64 285.143078170435 22.5824417520471 12.6267602636277 3.68450905722039e-32 -564.58498922488 64.333441666511 -8.77591769691962 2.29894833610459e-17 EPN2 other 4.46840115853825e-60 3.50520652805866e-13 5.45749481555484e-28 12.6267602636277 -8.77591769691962 4.15678530633152e-10 -53.6307997206578 53.5048327498901 -1.00235431014908 0.316622272623594 -997.862400860239 149.780966740406 -6.66214421348805 6.67496647047453e-11 PTPN18 other 3.47631955168505e-06 9.56789693877818e-07 1 -1.00235431014908 -6.66214421348805 0.344253378453934 -21.6178832069355 29.8362134244583 -0.724551835696891 0.469039667139992 -109.415903404623 76.7842798080512 -1.42497792097739 0.154739149025674 LIMS2 other 1 1 1 -0.724551835696891 -1.42497792097739 2.15755701550283e-11 28.6760966773713 24.8627939936292 1.15337385994186 0.249282787750562 -376.41364684057 61.445459652447 -6.12597983593374 1.77128120154843e-09 LNX1 other 1.92432510212698e-07 2.46774896999727e-05 1 1.15337385994186 -6.12597983593374 6.15519643735624e-32 730.532247387545 91.9577849999448 7.94421317768782 1.17573063045992e-14 -1506.04576514895 252.066119045738 -5.97480443167246 4.22504529135806e-09 ALDH3A2 other 8.57603519616846e-28 5.83436504283634e-05 1.49435363131455e-10 7.94421317768782 -5.97480443167246 2.8481995906242e-22 1607.98286337856 159.815438384238 10.0614989367457 6.12637842506731e-22 2022.90846580466 750.518098165246 2.69534934700438 0.00725106144674242 TFRC essential 3.5257862732337e-18 1 8.56590231392912e-18 10.0614989367457 2.69534934700438 8.46882519292236e-18 958.503232758622 533.003520505661 1.7983056319202 0.0727062232911621 -6590.24965106735 934.595198567394 -7.05144822182834 5.64241747010424e-12 SREBF1 other 9.51387822172898e-14 8.21987377044786e-08 1 1.7983056319202 -7.05144822182834 1.44473736273278e-16 354.114729843069 127.550364630891 2.77627375560875 0.00568906496075808 -1971.73482063325 297.068049429843 -6.63731702018294 7.77648945746002e-11 AFF4 og 1.5662397749386e-12 1.11343776051913e-06 1 2.77627375560875 -6.63731702018294 8.35464007548068e-15 106.430858229142 13.6911719817873 7.77368499721735 3.97966911296194e-14 -17.1609836974264 37.0809858485483 -0.462797396151167 0.643699193516874 UBE2D1 other 8.56267061336015e-11 1 5.00324000881575e-10 7.77368499721735 -0.462797396151167 6.44087895559898e-14 121.993026900892 35.3756207203483 3.44850562101149 0.000607943346173875 -338.386703356057 68.1659719977647 -4.96415870615258 9.28082719469884e-07 MPP5 other 6.38291104499859e-10 0.0118079964398153 1 3.44850562101149 -4.96415870615258 0.000277329756017163 35.7282173943623 22.9214679904855 1.55872291465768 0.11966000146769 -180.256879868462 58.5092807501758 -3.08082542730489 0.00217167011238442 RHOBTB1 other 1 1 1 1.55872291465768 -3.08082542730489 2.94376717663031e-12 318.716761524058 74.4677248372899 4.27993150348619 2.21900421801273e-05 -667.972904550618 175.103780520083 -3.81472577329082 0.000152391064086132 MARK2 other 2.73240469334825e-08 1 0.194517909750996 4.27993150348619 -3.81472577329082 0.00027588444778272 59.9291003751127 21.452754775263 2.79353868549397 0.00539684265140308 193.740656528908 51.3534248233714 3.77269202969955 0.000179185275577273 HMMR other 1 1 1 2.79353868549397 3.77269202969955 3.23918151010815e-08 83.1319781582136 15.4107830274249 5.39440325713965 1.03932984295869e-07 -30.0553594709007 37.2715166016416 -0.806389495553206 0.420381352395584 CHFR other 0.000242776654182606 1 0.00105990857384927 5.39440325713965 -0.806389495553206 0.380017497761826 3.70113309106348 3.48426317789715 1.06224269008784 0.288610209669494 13.1816081150158 12.3563211109077 1.06679067310573 0.286552984211281 TRHDE other 1 1 1 1.06224269008784 1.06679067310573 7.88281790174439e-08 274.863536718925 47.4627784014792 5.79113878235075 1.18204224944313e-08 208.202059958651 111.195348064576 1.87239901293118 0.0616866451902031 P4HA2 other 0.000574184455963061 1 0.000126194830550549 5.79113878235075 1.87239901293118 0.905846003479675 -1.40779461865287 7.7578843049028 -0.181466307478081 0.856069669331714 -34.225292964175 85.1712082723333 -0.401841111079935 0.687959955053375 FCGR2B og 1 1 1 -0.181466307478081 -0.401841111079935 1.57382292799547e-77 386.825797456828 32.550326262039 11.8839299594964 4.33629403157192e-29 -599.598753887458 72.5009569504631 -8.27021847859385 1.05060746954296e-15 NFATC3 other 2.44524868322657e-73 1.58610209676901e-11 6.3461663152055e-25 11.8839299594964 -8.27021847859385 6.32840579251525e-28 122.782802364959 12.1982671715602 10.065593796078 6.4092729971328e-22 -139.890316759345 30.6165055222792 -4.56911441632517 6.10393993863294e-06 TRNT1 essential 8.48386080544595e-24 0.0746328736296649 8.95952272269194e-18 10.065593796078 -4.56911441632517 2.50426752042642e-39 913.264254812337 162.190583514199 5.63080935418414 2.88498884983679e-08 -2873.01493395007 294.339782683493 -9.76087876316555 7.70932306550985e-21 ACADVL other 3.65623057982257e-35 1.19062785423734e-16 0.000303010378898358 5.63080935418414 -9.76087876316555 5.29148934462933e-05 77.944940933293 20.6412213511362 3.77617872544167 0.000176996132603752 -50.106193685046 55.2594248726782 -0.906744755315395 0.364947721137985 STK10 other 0.297910850102632 1 1 3.77617872544167 -0.906744755315395 7.74935809288954e-22 204.582748828959 31.8652538577812 6.42024537893339 2.98323845020077e-10 -447.225448315047 84.9814750696678 -5.26262280042105 2.05201232317197e-07 FBXW11 other 9.52163628873337e-18 0.00267705527681015 3.38806390789301e-06 6.42024537893339 -5.26262280042105 0.521574125703333 -6.75138144481998 12.7493158634545 -0.529548527711406 0.596642622700987 -26.5029425356853 23.2401694549426 -1.14039368719184 0.254627853632108 ACAP1 other 1 1 1 -0.529548527711406 -1.14039368719184 0.436227379104449 44.5335447635977 35.5579465722863 1.2524217244397 0.210951429411149 24.3679405432711 68.6848300027646 0.354779076286427 0.722891845005613 CRMP1 other 1 1 1 1.2524217244397 0.354779076286427 0.000385091297207819 -96.4887198231638 34.5873730539851 -2.78970940269332 0.0054598154833637 -258.245985352037 66.8696931866701 -3.86192867120132 0.000125980383615436 EVC other 1 1 1 -2.78970940269332 -3.86192867120132 8.14273224256476e-61 182.716507705884 19.1120445076054 9.56028056721896 3.97703711357994e-20 -381.185514367061 34.757851656962 -10.9668893845661 1.98590279698484e-25 DERL2 other 1.25267792819616e-56 3.09383796742267e-21 5.47677780911094e-16 9.56028056721896 -10.9668893845661 0.000666954034948147 25.3382017006685 53.9130858253736 0.469982404322762 0.638556279837197 -669.567720640597 180.872352043829 -3.70187987868011 0.000235856642908856 SIDT1 other 1 1 1 0.469982404322762 -3.70187987868011 0.0862901671616087 -46.2526828623004 24.6337259838588 -1.87761619547962 0.0609724403860813 16.909642318504 52.2906942019035 0.323377659765099 0.746534437520738 MRVI1 other 1 1 1 -1.87761619547962 0.323377659765099 0.00429233986427572 82.049039966863 25.1760021904149 3.25901782762399 0.00118769025296006 25.4592660935256 91.4725151661986 0.278326949327544 0.780866954311125 TMEM38A other 1 1 1 3.25901782762399 0.278326949327544 2.21268546921338e-32 245.493656687788 20.7712592924517 11.8189106029311 7.35975062422054e-29 -144.995651725054 74.2031700892843 -1.95403581208983 0.0512071094438484 AP1M1 other 3.09399809160107e-28 1 1.07636352879225e-24 11.8189106029311 -1.95403581208983 1.38551072236047e-18 194.509952726646 20.880498002661 9.31538858421182 2.94898066166299e-19 281.626751339616 69.6706413842092 4.04225862923441 6.05335697059819e-05 PVR other 1.58557847066933e-14 0.69389630953967 4.02181982637599e-15 9.31538858421182 4.04225862923441 1.04145134096284e-15 79.8438362966553 22.7604670249335 3.50800518324991 0.000488685963630673 -468.264217123333 73.5874191734332 -6.36337328286664 4.1823915958676e-10 XRCC1 other 1.10070992226362e-11 5.90846460748215e-06 1 3.50800518324991 -6.36337328286664 0.00116447251277152 334.942588591021 91.0128847966662 3.68016670759665 0.000256293453858056 151.046007772951 209.131849938118 0.722252530246564 0.470449584516234 SCARB1 other 1 1 1 3.68016670759665 0.722252530246564 1.15054108551541e-17 707.534419570955 77.3305120600853 9.1494857685826 1.17280358730367e-18 593.346647548275 248.045070716 2.3920920735717 0.0170942491937586 MCM2 essential 1.28734042058319e-13 1 1.58914886079647e-14 9.1494857685826 2.3920920735717 8.243491507096e-07 71.256733053951 14.0464602060385 5.07293168590033 5.41420254119925e-07 16.2945080927822 29.9252313286697 0.544507339436049 0.586319698526914 PANX2 other 0.00554869413342632 1 0.00529563150554698 5.07293168590033 0.544507339436049 7.08251231734969e-13 88.6153428602668 17.4948225211057 5.06523245682325 5.63049007426716e-07 -116.541030173254 37.2677912918129 -3.12712468685677 0.00186161744317746 SELENOO other 6.72767845025047e-09 1 0.00549929965553673 5.06523245682325 -3.12712468685677 0.104873852776272 -68.4570202374836 33.9038398144892 -2.01915242084844 0.0439658939910429 -94.4722481318846 143.216962939376 -0.659644264149598 0.509763888218484 TP63 other 1 1 1 -2.01915242084844 -0.659644264149598 4.44309198023239e-08 69.5210710461521 25.6788977676796 2.70732301966847 0.00699489104401173 -198.61978111665 55.6667768517663 -3.56801295763089 0.000391285710364706 ALPK1 other 0.000329544132173837 1 1 2.70732301966847 -3.56801295763089 5.35477854463646e-31 714.754391419707 61.7088615300127 11.5826864035091 7.65298623942536e-28 -548.97989730635 211.14604331086 -2.60000087474106 0.00957945035733831 LLGL2 other 7.39602012585188e-27 1 1.11404520687315e-23 11.5826864035091 -2.60000087474106 2.42127501744758e-10 110.585256795134 16.2933599422324 6.78713642779696 3.0237367260169e-11 88.2468132981734 42.7850725515425 2.06256079598472 0.0396329292935706 PDE8A other 2.05275695979206e-06 1 3.53656247474936e-07 6.78713642779696 2.06256079598472 1.40720309892034e-48 150.071850621128 10.1676171616836 14.7597857231161 1.25011257279576e-41 -31.5020450851057 27.5793706199076 -1.14223219663927 0.253866550014762 NLE1 essential 2.11952930759381e-44 1 1.89467061532926e-37 14.7597857231161 -1.14223219663927 4.25524785700913e-18 479.743641545709 52.807964323136 9.08468348846247 2.14717424451875e-18 -95.6972328331445 229.02596691797 -0.417844465939621 0.676232659853278 SDHA ts 4.81311085106303e-14 1 2.89954409979812e-14 9.08468348846247 -0.417844465939621 3.13917898835362e-94 948.939137227653 41.3936402770368 22.9247568195658 3.05926130442304e-81 -1084.27644168253 195.488365381807 -5.54650114120523 4.61375517129134e-08 SMARCE1 other 4.8993166471235e-90 0.000617597267229059 4.76663503842153e-77 22.9247568195658 -5.54650114120523 3.47351346198447e-19 6.51995629734437 0.732822042056691 8.89705265830418 8.76800770811193e-18 0.168489568797651 1.98584043330329 0.0848454719583796 0.932415864110278 FNDC8 other 4.03483323744116e-15 1 1.1753514332724e-13 8.89705265830418 0.0848454719583796 1.99577548213122e-59 145.437813636213 7.7898409154883 18.6701904716749 7.25387009370544e-60 50.1035694083932 159.712082053572 0.31371182921269 0.753866204091346 GSDMB other 3.06351536507142e-55 1 1.12072292947749e-55 18.6701904716749 0.31371182921269 6.56463779202855e-37 551.048132664679 42.755291884066 12.8884193834738 3.59061194378271e-33 -281.173046164652 163.878501095697 -1.71574089514316 0.0868062744772008 KDM5A other 9.46949001500119e-33 1 5.33708559323862e-29 12.8884193834738 -1.71574089514316 0.0509597136831004 5.14930139436974 2.29720556931592 2.24155010903232 0.0253950940988739 -0.28368977361602 5.41470310622633 -0.0523924891264687 0.958235298219396 ADAM11 other 1 1 1 2.24155010903232 -0.0523924891264687 8.39830994776602e-11 231.282877326547 34.5267687390886 6.69865399436311 5.26047632435314e-11 -84.7288014685892 122.581675686319 -0.691202832676285 0.489732930751212 PPP2R3A other 7.27041692178104e-07 1 6.10425672677938e-07 6.69865399436311 -0.691202832676285 0.0325733715561442 116.036233640191 66.8705691989697 1.73523621871576 0.0832684309009628 -214.066565907825 159.227432206158 -1.34440757438495 0.179380054823467 FERMT2 other 1 1 1 1.73523621871576 -1.34440757438495 0.684019698019541 -15.2035070763891 26.1970103516677 -0.580352752940042 0.561917956166334 -54.2686442655809 68.6100307602952 -0.790972452048314 0.429306040949111 DHRS9 other 1 1 1 -0.580352752940042 -0.790972452048314 0.000731260405336275 180.126475149994 47.4250806523802 3.79812691243054 0.000162872716136571 -58.926031496657 322.124135850419 -0.182929575708726 0.854924031023318 PTGS2 other 1 1 1 3.79812691243054 -0.182929575708726 3.46682233733251e-06 67.7437491016478 18.1963808818066 3.72292432993532 0.000217523115125996 258.326797252045 73.8522351924933 3.49788732295949 0.000507467351318664 IGF2BP2 other 0.0219935209080375 1 1 3.72292432993532 3.49788732295949 2.83346644500039e-16 209.413997121244 24.1839112256368 8.65922782991569 5.45410661662316e-17 -110.660241019878 98.3801469658534 -1.12482288787683 0.261161971632074 MAP3K13 other 3.04682646830892e-12 1 7.2250550350407e-13 8.65922782991569 -1.12482288787683 2.34778457395639e-06 597.377089528152 118.763878899888 5.02995603597381 6.6885190455172e-07 -512.138628237471 495.149053840742 -1.03431204051577 0.301453283817251 ST6GAL1 other 0.0151666883477583 1 0.00650458477176548 5.02995603597381 -1.03431204051577 0.00189037527130796 -0.854628404066568 1.25387439484562 -0.681590123843139 0.495796441914992 10.6622204933961 3.44493996227181 3.09503811682242 0.0020720302661359 TBX21 other 1 1 1 -0.681590123843139 3.09503811682242 5.80437482957965e-12 -171.742550517 50.0500798495144 -3.4314141162887 0.000647128929313408 -727.349559256301 98.7281049338735 -7.36719862842975 6.68804480673297e-13 FRY other 5.32493346865637e-08 9.8427955420689e-09 1 -3.4314141162887 -7.36719862842975 1.4991409733817e-39 907.423069869251 91.4874395492225 9.91855356691926 2.2961274554189e-21 -949.886580335977 207.969721152607 -4.56742729216314 6.16144161449813e-06 PICALM other 2.19129436079203e-35 0.0753297851788542 3.19575019245202e-17 9.91855356691926 -4.56742729216314 1.25270860189613e-42 479.759263231523 43.0809866130744 11.1362181080116 5.1674079391253e-26 -589.717382164905 106.041218606632 -5.56120902714731 4.26464917287902e-08 NSF essential 1.85463508510722e-38 0.000571462989165789 7.44468461789782e-22 11.1362181080116 -5.56120902714731 0.0971572309184158 -11.0466314122446 7.06091993950734 -1.56447481445531 0.11829299762217 -31.7773510123893 17.1047008110931 -1.85781390527336 0.0637405336026286 GLI2 other 1 1 1 -1.56447481445531 -1.85781390527336 9.09489251969643e-08 142.46679916069 38.7409473304235 3.67742166823085 0.000259222259998793 -317.303156040454 95.4409669346434 -3.32460122976057 0.000945662437764643 CLASP1 other 0.000659379707677991 1 1 3.67742166823085 -3.32460122976057 3.33356669658976e-18 378.607887606381 46.3450922779675 8.16931996457307 2.18910304232677e-15 -324.608384958482 212.136467731938 -1.53018662198462 0.126552876512868 MRPS34 essential 3.78026463393279e-14 1 2.81803234638725e-11 8.16931996457307 -1.53018662198462 1.95454072330732e-24 3222.81818296916 295.674310336504 10.8998924502481 3.84958116112546e-25 1604.51805161586 1023.31324297417 1.56796373215348 0.117475365218029 NOTCH3 other 2.50493939099066e-20 1 5.51914451070557e-21 10.8998924502481 1.56796373215348 8.33453120213967e-157 791.465953168582 20.6397437777522 38.3466946920975 1.49014290379739e-151 -254.082134757926 125.35845962883 -2.02684474195224 0.0432042251001527 CLNS1A essential 1.30560431281518e-152 1 2.33415984450824e-147 38.3466946920975 -2.02684474195224 2.98789063926534e-07 266.977654020848 68.2419207506189 3.91222361686568 0.000103032777542885 -195.328758693404 131.117127991786 -1.48972725139038 0.136875491219514 PPP2R2C other 0.0020843525099515 1 0.850226480283887 3.91222361686568 -1.48972725139038 0.00177341345401532 186.031439268519 52.2188373914775 3.56253506515027 0.000399413877789096 99.6566523156927 183.792619593372 0.542223363137084 0.587885865959998 TEAD2 other 1 1 1 3.56253506515027 0.542223363137084 0.000389551214512001 5.53455432311291 1.3934898227024 3.97172209868007 8.10821861971582e-05 3.96144708145863 3.95234404987081 1.00230319817125 0.316648601612852 CDHR2 other 1 1 0.675738939767117 3.97172209868007 1.00230319817125 6.65679686740968e-37 323.168423004817 36.428301164546 8.87135585996917 1.02978208903645e-17 -631.758952945708 91.4220270652743 -6.91035818418945 1.35209680658095e-11 TSG101 essential 9.60043244217823e-33 1.95986432113909e-07 1.37887821721981e-13 8.87135585996917 -6.91035818418945 1.18152880651082e-57 192.489930259742 22.4526105492141 8.57316479247798 1.03132245186611e-16 -463.890131336454 41.3672277915064 -11.2139525924843 2.04264419809024e-26 NCBP3 other 1.81010213157458e-53 3.18632068460096e-22 1.35897359482397e-12 8.57316479247798 -11.2139525924843 1.80411699938125e-05 457.435053290235 266.556999874458 1.71608719150379 0.0867112511903324 -1618.29206896262 491.111005068105 -3.29516555781152 0.00104722324816927 ATP2A3 other 0.107218673273228 1 1 1.71608719150379 -3.29516555781152 1.31420778825339e-25 4710.11334276659 692.281821840513 6.80375129632062 2.71453366243006e-11 -10271.2526531723 1528.00676187243 -6.72199424077538 4.56777428989118e-11 CA12 other 1.71214990653652e-21 6.56571876428958e-07 3.17899037207184e-07 6.80375129632062 -6.72199424077538 0.661749727991444 149.216854470139 164.148094250716 0.909037994935401 0.363735602281812 104.277215095239 535.714404662793 0.194650758291401 0.845739572248141 MGLL other 1 1 1 0.909037994935401 0.194650758291401 4.40929661779551e-09 -449.706866584018 201.60428670308 -2.23064139130305 0.0261126143632743 -3465.14040605056 551.235013286165 -6.28613989048567 6.69013399708527e-10 NTN4 other 3.48731269501447e-05 9.41101149369984e-06 1 -2.23064139130305 -6.28613989048567 4.33131921065722e-13 82.5579817247021 12.099921166112 6.82301814956618 2.38297387461374e-11 -46.8692689219486 27.5706181265689 -1.69997164034499 0.0897078654582745 BCS1L essential 4.14680501228322e-09 1 2.79618154447176e-07 6.82301814956618 -1.69997164034499 0.0529358513953118 3.71257666814766 29.3806941433043 0.126361094466985 0.899492785423977 -163.159132736866 71.8569412675235 -2.27061060293986 0.0235606947821819 NUAK1 other 1 1 1 0.126361094466985 -2.27061060293986 6.65305816071398e-37 309.461432518952 30.0368308311088 10.3027324773041 7.65809455642967e-23 -434.162555021804 68.3536630712598 -6.35170867974087 4.53031949267018e-10 DPP8 other 9.59570578519778e-33 6.39454596390396e-06 1.08017423718441e-18 10.3027324773041 -6.35170867974087 3.58299922897579e-30 99.1891285243231 15.5281929605598 6.38768005886161 3.63766071177917e-10 -305.169714268761 35.4698877886419 -8.60362784588457 8.43074702281332e-17 SLC24A1 other 4.90906724361973e-26 1.28122062505694e-12 4.12001452216109e-06 6.38768005886161 -8.60362784588457 5.07787439289963e-07 339.622125174204 66.6762876162851 5.09359679904036 4.85743998762579e-07 49.9423354347927 146.215749445533 0.341566046230859 0.732809877043529 ZNF532 other 0.00347428165962192 1 0.004769034579851 5.09359679904036 0.341566046230859 0.00221828591575864 -21.6602382071691 8.27883783839312 -2.61633802110723 0.00913621693232566 -48.8873685578913 15.1967556699499 -3.21696088426039 0.00137305086297155 SCARF1 other 1 1 1 -2.61633802110723 -3.21696088426039 1.89074323755448e-19 1299.19408766051 154.708964704449 8.39766519117007 4.00194222132063e-16 -279.744081331194 338.023706796025 -0.827587165358202 0.408268565469826 LMAN1 other 2.21330403388128e-15 1 5.21893285082424e-12 8.39766519117007 -0.827587165358202 4.34477327689837e-25 1431.99719764882 213.959743870592 6.6928346975164 5.49263571160493e-11 -3309.57850437404 483.301020086918 -6.84786161589073 2.0457172275828e-11 HACD3 other 5.61692289237421e-21 2.95708425247093e-07 6.36926037117707e-07 6.6928346975164 -6.84786161589073 0.360088315552643 0.902959340008362 4.30277301703668 0.20985521114712 0.833859393807789 -10.5226602076775 9.26915405434209 -1.13523414822825 0.256778068643926 IPCEF1 other 1 1 1 0.20985521114712 -1.13523414822825 1.16770125684593e-28 159.01290034965 41.6182457892399 3.82074970566784 0.0001482768087928 -680.879090109206 76.9723717836093 -8.84575951515884 1.24766965712592e-17 ZZEF1 other 1.57756439799885e-24 1.90456773160272e-13 1 3.82074970566784 -8.84575951515884 6.28764369489066e-15 10443.7836066663 1301.07435606915 8.02704592396965 6.27199327804209e-15 4239.1259884792 2150.00709800992 1.97167999696513 0.0491561525748943 ENO1 essential 6.47627300573738e-11 1 8.00933541605975e-11 8.02704592396965 1.97167999696513 0.348567323480235 -4.69916797304346 12.9740713250277 -0.362196865989052 0.717347944241013 24.8100635145923 22.7352274717043 1.09126084379276 0.275649328818699 SLC12A1 other 1 1 1 -0.362196865989052 1.09126084379276 1.85132586964094e-12 319.675756596264 60.8757888505328 5.25127908208562 2.16614099645684e-07 -498.249127098331 158.169615572034 -3.15009381097861 0.00172138264883833 MYDGF other 1.7313599532882e-08 1 0.00217133973484833 5.25127908208562 -3.15009381097861 4.42667697443042e-19 121.267535446206 15.7143050976952 7.71701546408132 5.74747059712158e-14 -179.487267498046 53.3451664074906 -3.36463975249392 0.000820574076662167 ANO8 other 5.1309612810623e-15 1 7.19813217583507e-10 7.71701546408132 -3.36463975249392 1.0921864633984e-31 50.1491129627766 5.65017147871314 8.87567981816338 1.03205683858948e-17 -72.406005095351 16.1582661681281 -4.4810504011978 9.07956888777002e-06 TUBE1 essential 1.51802996547744e-27 0.109908181386456 1.38182090118746e-13 8.87567981816338 -4.4810504011978 1.98026087284199e-06 175.179958634287 52.9593299325585 3.30782052675839 0.00100203674479247 -139.471541345152 85.1801642745337 -1.63737112428709 0.102128063124427 ARHGEF10L other 0.0128855574995828 1 1 3.30782052675839 -1.63737112428709 0.143580765740584 -1.4862021072125 0.857333562604192 -1.73351676878027 0.0835789156801074 -3.05150389081401 1.91477384508848 -1.59366282270949 0.111601058555846 TXK other 1 1 1 -1.73351676878027 -1.59366282270949 0.797068338118303 4.03765475003655 6.2758927195719 0.643359427965488 0.520260520010794 5.60176799353648 14.4937779894193 0.386494673619663 0.69928064343319 WSCD2 other 1 1 1 0.643359427965488 0.386494673619663 0.0061340399750114 11.6159219986826 5.45522264962597 2.1293213393369 0.033702303267678 100.26245182148 37.8476575997213 2.64910586757735 0.00831883757969039 KCNQ2 other 1 1 1 2.1293213393369 2.64910586757735 0.0965934235493636 3.28464713601682 3.18491039252526 1.03131540018383 0.302848712613887 -12.6701887136596 8.4958431976064 -1.49133975509685 0.136448763357692 TACR2 other 1 1 1 1.03131540018383 -1.49133975509685 1.10629297583947e-15 120.686617779179 17.095817028884 7.05942380965324 5.17231240016755e-12 -109.989391190828 42.3012959330162 -2.60014235414904 0.00957411320779753 ACTR6 essential 1.16791349459373e-11 1 6.18298224316029e-08 7.05942380965324 -2.60014235414904 2.8586130112553e-13 42.7333169560481 5.55498222357694 7.69279094623843 6.89311805503059e-14 10.1019602755462 12.7826251898071 0.790288389555651 0.429706920367313 TIPIN other 2.76284947537825e-09 1 8.61708688059374e-10 7.69279094623843 0.790288389555651 0.000509502334074464 42.8644311172309 89.4096062926986 0.479416394888334 0.631834748035517 -1041.07340256024 287.620172288932 -3.61961191482223 0.000322539627700673 SRI other 1 1 1 0.479416394888334 -3.61961191482223 4.74661466006042e-18 239.835817147859 90.2855880016137 2.65641308271229 0.00812950364727504 -922.814663219638 149.289593463916 -6.18137300670381 1.24763294885998e-09 EIF4G3 other 5.36225058147026e-14 1.74406609921137e-05 1 2.65641308271229 -6.18137300670381 1.6570836571824e-14 75.6941722619472 10.8069601939178 7.00420570666564 7.36223989748227e-12 -52.3927280015563 26.1067671809938 -2.00686387702952 0.0452584469396868 NUP37 other 1.67879145309149e-10 1 8.76474659795265e-08 7.00420570666564 -2.00686387702952 0.080260979981339 11.8286871630423 5.25658231889182 2.25026194691764 0.0248317864883116 8.42372848605379 16.4686758335113 0.511500048407824 0.609208886244362 SEMA3A other 1 1 1 2.25026194691764 0.511500048407824 3.18326351521951e-18 169.026086674328 19.1461951040368 8.82818156588668 1.48312779437143e-17 65.1977887527918 36.8472488546283 1.76940723607381 0.0773902795231574 GTSE1 other 3.61202201109861e-14 1 1.98056885660361e-13 8.82818156588668 1.76940723607381 0.000102568091385729 -307.106608389832 232.524103009119 -1.32075171741567 0.187142572144108 -3191.35708933977 739.061236864159 -4.31812268071414 1.8721113729973e-05 SEMA3C other 0.556637031950353 0.222313225543429 1 -1.32075171741567 -4.31812268071414 1.31848889406843e-13 25.9727687067472 24.2480752807565 1.07112702373369 0.284590813635972 -293.344013238128 46.6659228771472 -6.28604332995591 6.71963838808051e-10 TTC38 other 1.29211911618706e-09 9.45184335667405e-06 1 1.07112702373369 -6.28604332995591 8.42600490175373e-15 221.138004439193 73.9027409886119 2.99228420327833 0.00289579845317526 -648.285957911119 141.191502966186 -4.59153663139614 5.48144522255298e-06 ACAT1 other 8.63412722282704e-11 0.0672134813189446 1 2.99228420327833 -4.59153663139614 5.62193973510078e-22 166.437370154841 33.5498184805593 4.96090225499383 9.41580323986771e-07 -347.673883403334 64.3808578553362 -5.40026795207602 9.98704252355926e-08 GRAMD4 other 6.92454317172363e-18 0.00132198481884354 0.00907400958226051 4.96090225499383 -5.40026795207602 1.12617150293906e-12 -803.57141447015 359.003682411095 -2.2383375264379 0.0256057935824055 -5132.37462249814 690.910019126489 -7.428426973728 4.3193541172861e-13 CELSR1 other 1.06209234442183e-08 6.37061538758527e-09 1 -2.2383375264379 -7.428426973728 0.00116634622840615 51.7370174317791 62.0035538403228 0.834420194123339 0.404410504857179 -720.163696180303 209.958465860499 -3.43002933093823 0.000649311067737475 ZNF638 other 1 1 1 0.834420194123339 -3.43002933093823 1.56982796832387e-11 46.0415484291046 13.9242022013129 3.30658430288834 0.00100672921282534 -242.919058407028 45.3467226127139 -5.35692646372024 1.25149233347553e-07 SLC25A40 other 1.40782172199285e-07 0.00164896629858736 1 3.30658430288834 -5.35692646372024 1.02647043090826e-39 147.714699381313 11.6746186220987 12.6526359586347 2.68364409081496e-32 -29.4247247707114 23.6148920277607 -1.24602410784351 0.213298865817236 TIMM21 other 1.5016235933757e-35 1 3.97689217817868e-28 12.6526359586347 -1.24602410784351 2.94436097069942e-06 117.315675183929 23.8776695702908 4.91319619105105 1.18793668502828e-06 172.894713360423 79.2413542336636 2.18187479293448 0.0295467556765685 ADD2 other 0.0188203553247107 1 0.011383997252626 4.91319619105105 2.18187479293448 2.30049263649335e-07 108.000329842293 19.2708906720717 5.60432476526954 3.50067832701433e-08 96.700643712378 188.617271513829 0.51268180764288 0.608405893044335 FGF4 other 0.00161954681609132 1 0.000365995919089348 5.60432476526954 0.51268180764288 0.00118640970843466 83.0423164090535 22.498601706969 3.69099900032148 0.00024591951340957 64.8128604560931 158.226129071263 0.409621728323407 0.682244994456505 RASAL2 other 1 1 1 3.69099900032148 0.409621728323407 7.94209106120635e-22 52.7924603389254 12.9268062693726 4.08395231109839 5.11458758144986e-05 -134.952087953697 27.8825697747449 -4.84001614786353 1.70709437514701e-06 VPS9D1 other 9.75447624137363e-18 0.0214445195405968 0.434023902161835 4.08395231109839 -4.84001614786353 0.000656919766095559 31.3545760130231 27.3713242604614 1.14552645369503 0.252539126209692 -359.583010572112 107.73621047604 -3.33762445312742 0.000907946684015721 ZNF37A other 1 1 1 1.14552645369503 -3.33762445312742 9.45873993029776e-42 229.342695571412 22.6219087607996 10.1380788861119 3.0859155345385e-22 -290.833924851585 47.227199038562 -6.15818703569765 1.43254660918485e-09 MARK3 other 1.39573166411474e-37 1.99983506642205e-05 4.32707076252988e-18 10.1380788861119 -6.15818703569765 4.17079977977713e-16 746.032532152367 134.442928240395 5.54906488512658 4.50564606991508e-08 -1552.21458733775 327.611153110469 -4.73797846196751 2.76356105126396e-06 SLC25A3 essential 4.46150452442759e-12 0.0344008079661337 0.000468902586496062 5.54906488512658 -4.73797846196751 1.00939220459419e-14 624.953711777579 76.2904267913571 8.19177107878468 1.92583009255561e-15 468.001451403543 324.917046369291 1.44037210922947 0.150350380637779 FNDC3B other 1.03069038011113e-10 1 2.48200982328567e-11 8.19177107878468 1.44037210922947 0.0210261058766221 -90.1248213941003 132.976957329135 -0.677747657972272 0.49821985000682 -1131.79183851473 405.947704951409 -2.78802373978245 0.00548858295472804 FOSL2 other 1 1 1 -0.677747657972272 -2.78802373978245 2.59290424226138e-17 473.552473341285 92.1961272278823 5.13635971032492 3.95721903731591e-07 -2455.1605461276 382.953105912824 -6.41112582250867 3.22624414133861e-10 CACNG4 other 2.87475293339519e-13 4.5677164553072e-06 0.00390814952125319 5.13635971032492 -6.41112582250867 7.76899246790266e-11 220.446469889846 72.9801401948646 3.02063642658442 0.00264390489491005 -712.658317523917 160.858599798242 -4.43034017713555 1.14324697234592e-05 FRYL other 6.74193166364593e-07 0.137521178303491 1 3.02063642658442 -4.43034017713555 2.39987605387908e-08 104.561157014039 48.056324318595 2.17580429832375 0.0300003676718774 -882.645808665024 171.868665035078 -5.13558308307613 3.9265447492511e-07 TMEM131 other 0.000181502625954875 0.00507034723470794 1 2.17580429832375 -5.13558308307613 0.00868607051548466 538.479006371821 180.962278712718 2.97564227308758 0.00305516788579458 1014.59884123541 641.301969979777 1.58209219483203 0.114216190285133 FSCN1 other 1 1 1 2.97564227308758 1.58209219483203 8.5528109767163e-09 13727.5226078588 2226.94316951289 6.16428959471899 1.39009711636877e-09 7214.23994722936 7891.9377662614 0.914127830311936 0.361059172976337 ACTB essential 6.64296828561555e-05 1 1.53814245926205e-05 6.16428959471899 0.914127830311936 8.04120476267691e-09 164.720059071048 35.3100790272237 4.664958663617 3.89324387152052e-06 -151.869856552238 76.4695865807402 -1.98601644579164 0.0475348028772101 MOCOS other 6.25605730536264e-05 1 0.0360864774451237 4.664958663617 -1.98601644579164 0.000810317462114588 125.825179523584 33.1365566620014 3.79717122714418 0.000163184709544903 35.1156758540319 139.801504273216 0.251182389178052 0.801769906364082 PLD1 other 1 1 1 3.79717122714418 0.251182389178052 4.81980898157531e-21 144.998479926415 14.4122578656334 10.0607747431559 6.077287766693e-22 71.4943514850726 66.5402534856507 1.07445264693033 0.283098830711977 WDR62 other 5.82859500141903e-17 1 8.49908694172017e-18 10.0607747431559 1.07445264693033 3.72452633005504e-26 383.517805178344 33.7760739126041 11.3547183183783 6.93563630860043e-27 -199.482200482375 142.561943770797 -1.39926683942449 0.162320165920184 DLG1 other 4.89030307136226e-22 1 1.00386399930683e-22 11.3547183183783 -1.39926683942449 1.84369726984279e-33 1189.70803699008 101.120850677914 11.7652099345909 1.31605240014834e-28 -1192.73004142631 333.910109286441 -3.57200937694026 0.000385912670524085 RAB7A other 2.60090373856722e-29 1 1.9224893461367e-24 11.7652099345909 -3.57200937694026 3.74322797441207e-09 128.542801370403 35.8499770179237 3.58557555855994 0.000366722802155454 -418.905169379992 107.333120324906 -3.90285093838635 0.000107038702875214 BCAP29 other 2.97287165727807e-05 1 1 3.58557555855994 -3.90285093838635 3.29146254872132e-09 12.5174086648345 8.74897237033017 1.43072901993427 0.153078898253973 -88.873430736894 17.210177299395 -5.16400436734713 3.39019744030613e-07 SEC31B other 2.62230821256628e-05 0.00438861058647629 1 1.43072901993427 -5.16400436734713 1.04426927894783e-18 170.060549255366 27.792369755655 6.11896541210785 1.79627887394037e-09 -319.562538039946 63.9354766830523 -4.99820373005296 7.80203473317594e-07 SART3 essential 1.1990299860879e-14 0.00995851713342577 1.97842155175792e-05 6.11896541210785 -4.99820373005296 0.461571129171363 -10.3611390312947 8.90216293430783 -1.16389006893641 0.244990275082203 0.602232702835696 20.8099390738742 0.02893966679565 0.976923562119604 ARHGAP15 other 1 1 1 -1.16389006893641 0.02893966679565 0.207505425381619 -18.2149879742804 34.796096699647 -0.523477909936525 0.600856867199572 -163.426413339612 92.0285749918725 -1.77582249159074 0.0763262988058463 TUBA3D other 1 1 1 -0.523477909936525 -1.77582249159074 0.12406870680479 7.83904925103654 7.54069247366636 1.03956623060974 0.29900159604175 -17.5871384447589 14.727807354522 -1.19414506324046 0.232939753633856 PAX2 other 1 1 1 1.03956623060974 -1.19414506324046 0.000302426544666438 110.322910160792 42.0766483307409 2.62195099984214 0.0089858385961754 -116.450765029198 80.1487279798625 -1.4529334147194 0.146814603954554 EXOSC7 essential 1 1 1 2.62195099984214 -1.4529334147194 1.27595915024367e-15 163.723292041028 19.2811172446203 8.49137993218255 1.97735302401908e-16 -63.6187223072241 142.295174926538 -0.447089807086348 0.654989152932567 KIFAP3 other 1.34435056069673e-11 1 2.59270528509382e-12 8.49137993218255 -0.447089807086348 1.10034407410983e-22 141.629163123073 14.2624034442876 9.93024518457289 1.87322041828723e-21 -39.0389262737336 36.3894824243889 -1.07280795638822 0.283837364478148 MKRN2 other 1.37223909482237e-18 1 2.60920872063228e-17 9.93024518457289 -1.07280795638822 1.21313396639944e-09 525.84899990376 83.6344534272408 6.28746860121745 6.63699857305248e-10 724.394462915878 192.15207099791 3.76990192795662 0.000181216497075574 MCM6 essential 9.88582869218903e-06 1 7.43742060096261e-06 6.28746860121745 3.76990192795662 3.59219436725848e-36 208.913137874877 29.3329012157921 7.12214370948086 3.37581794355092e-12 -310.674560446905 53.9982493889906 -5.75341911936588 1.45971797996851e-08 REXO2 other 5.16449784180752e-32 0.000198623825534315 4.05570767738207e-08 7.12214370948086 -5.75341911936588 3.05462794979611e-37 119.832393713938 16.4093792325888 7.30267684203144 1.00386944659608e-12 -175.011870611073 30.3176419088174 -5.77260827664088 1.31013572188713e-08 RBM7 other 4.41454831304533e-33 0.000178558397535997 1.21940021678026e-08 7.30267684203144 -5.77260827664088 0.500383845903712 5.68396913072717 23.574190260887 0.241109835282771 0.809561679301159 -73.2455912331242 69.7123882867137 -1.05068256924263 0.29387524164883 RBMS2 other 1 1 1 0.241109835282771 -1.05068256924263 1.32099491219339e-17 420.206272323631 86.015218268279 4.88525496747587 1.36392754679554e-06 -1576.8810808864 254.359798921003 -6.19941157201548 1.1279379249662e-09 BAZ2A other 1.47568341641123e-13 1.57809795082022e-05 0.013021416289257 4.88525496747587 -6.19941157201548 3.3849728537929e-27 79.7416300056791 38.9810404124304 2.04565165942187 0.0412922932915002 -649.587032794154 72.2922630315533 -8.98556782640252 4.72499625949169e-18 PTPN23 essential 4.50201389554456e-23 7.22735427851849e-14 1 2.04565165942187 -8.98556782640252 9.2855199867245e-27 90.8950440998113 23.0689902971989 3.94013968226636 9.20640000671911e-05 -381.684812456711 45.5437914383752 -8.38061128426614 4.53346375822127e-16 MLH1 ts 1.22856714944352e-22 6.85777062706132e-12 0.763118496556947 3.94013968226636 -8.38061128426614 2.72958492286729e-10 311.810239600851 47.3494507542577 6.58529792075388 1.06840114518777e-10 53.8918382680998 109.304413957305 0.493043568113822 0.622180032026602 UNG other 2.30404263339228e-06 1 1.23005023845467e-06 6.58529792075388 0.493043568113822 0.0730367797009635 8.99025870681366 4.03802300833997 2.22640106018355 0.0263975858996896 -11.90800312708 29.3919893798094 -0.405144509723458 0.685531150479868 FMO4 other 1 1 1 2.22640106018355 -0.405144509723458 2.14718488626751e-12 50.7854965138452 6.93946142161711 7.31836282793408 9.18884929524886e-13 -63.3329059309748 51.1217092932455 -1.2388651867582 0.215935649661996 KLHL20 other 2.00139103248994e-08 1 1.1170884088234e-08 7.31836282793408 -1.2388651867582 1.35074641837243e-07 71.7512766596138 18.292597497536 3.92242144229537 9.93056256647062e-05 -203.212036730471 80.9976370552849 -2.50886376588701 0.0124122285139344 RGS11 other 0.000968350107331195 1 0.820959607370127 3.92242144229537 -2.50886376588701 6.82257730854583e-29 285.54321628382 34.9683302237142 8.16576640797609 2.52462980644454e-15 -751.238186590047 129.330670798249 -5.8086622604931 1.10936184605498e-08 SLC46A1 other 9.24390999534874e-25 0.000151372423894202 3.2456640791651e-11 8.16576640797609 -5.8086622604931 0.967299622847763 3.91087038540994 21.8848676903609 0.178702034700099 0.858238944547563 -28.4379632632443 155.385244839044 -0.183015853871465 0.854854526527805 PLXNA2 other 1 1 1 0.178702034700099 -0.183015853871465 1.68833480975622e-39 444.809849162879 30.4422996826265 14.6115718523306 1.21571056783982e-40 483.379529177112 112.591107822627 4.29323006518967 2.10829454194547e-05 SPAG5 other 2.46682599053482e-35 0.249474493148408 1.83937008914165e-36 14.6115718523306 4.29323006518967 0.000296835415587625 49.5742517823803 33.8412462469104 1.46490621003375 0.143530622237813 -241.285116592002 75.8708128873936 -3.1802099833847 0.00155645682638762 ANKRD13A other 1 1 1 1.46490621003375 -3.1802099833847 9.52162122448188e-25 1911.75095549562 176.253801787081 10.8465799665704 7.91715806072498e-25 -2661.84596147712 1771.09604067247 -1.50293710806696 0.133468192575886 TPD52 other 1.22609916507653e-20 1 1.13270780374792e-20 10.8465799665704 -1.50293710806696 0.0213815332627798 269.841858531449 130.854654660356 2.06214948357661 0.0396669387565017 -348.901602507697 302.014217667744 -1.15524893232522 0.248494738236857 ACACB other 1 1 1 2.06214948357661 -1.15524893232522 6.37994767458534e-39 889.755363666922 63.7670004526093 13.9532259217395 9.65354661209931e-38 205.151740744264 245.038436457289 0.837222697427807 0.402857254295888 TRAF4 other 9.30068772001051e-35 1 1.45170033952749e-33 13.9532259217395 0.837222697427807 0.0569777364558449 18.4728530815229 8.16084889643533 2.26359454953171 0.0240143562587421 86.3075222759155 83.43397247706 1.03444100422817 0.30141553919445 PAG1 other 1 1 1 2.26359454953171 1.03444100422817 1.5258718118967e-31 64.9051888183768 6.17737159294682 10.5069264236077 1.28472524460724e-23 -136.234855051836 28.2254307865135 -4.82667053276406 1.81055480012625e-06 GPATCH1 other 2.11791007491262e-27 0.022715220522384 1.8232820671466e-19 10.5069264236077 -4.82667053276406 6.40416953549924e-08 32.6125932070625 10.8751444532788 2.99881931197982 0.00283448195099609 -167.571643914832 40.2320735835073 -4.16512570665823 3.61936766354854e-05 ICAM3 other 0.000470002002210289 0.421077233977237 1 2.99881931197982 -4.16512570665823 5.87808653608119e-06 283.862930768758 60.591231220496 4.68488467804458 3.54188714077488e-06 392.038298501941 125.691476938276 3.11905236577387 0.00191023870164263 NT5C2 other 0.036420624177559 1 0.0329253828606432 4.68488467804458 3.11905236577387 2.0179581043549e-67 731.192246427762 37.5026097223773 19.4971030507104 1.12431707915815e-64 -50.7692447232357 135.597090513405 -0.374412493151664 0.708242549194206 CAMSAP3 other 3.11855245447006e-63 1 1.74089256536848e-60 19.4971030507104 -0.374412493151664 2.18811546406832e-07 190.184064042444 61.2783867733503 3.10360755327772 0.00201059209045811 -250.209967839091 102.488187446419 -2.44135420942926 0.0149482126076301 RAP1GAP other 0.0015437154599002 1 1 3.10360755327772 -2.44135420942926 3.06771548697464e-82 1144.30436701112 50.8059014125717 22.5230600224715 5.63508316513599e-80 71.7150539479382 183.697413685452 0.390397733474555 0.696394448032272 XAB2 essential 4.77459238392733e-78 1 8.7766420296993e-76 22.5230600224715 0.390397733474555 4.58515514008943e-58 1068.46657821603 62.5766369583719 17.0745286124406 1.03880704987413e-52 -504.738754125147 226.256518372528 -2.2308252498348 0.0260973639331904 STXBP2 other 7.02812579872907e-54 1 1.59623091283659e-48 17.0745286124406 -2.2308252498348 5.31011002142496e-30 183.041187850256 21.7298150113842 8.42350419248209 3.25681554060121e-16 -341.638492785195 60.3829964865564 -5.65785920977368 2.47848497527477e-08 MAP2K7 other 7.26423050930935e-26 0.000334570686812341 4.25470382224142e-12 8.42350419248209 -5.65785920977368 1.49136325249582e-11 136.952780962092 62.5684538383565 2.18884713558537 0.0290291784158804 -723.273274327056 122.725708427906 -5.89341290909669 6.61278808966803e-09 DGKD other 1.3393933370665e-07 9.08597083520387e-05 1 2.18884713558537 -5.89341290909669 0.453631781163384 -41.7540379560888 45.9203296498003 -0.909271302591148 0.363613331236538 -159.389195511745 143.159171215107 -1.11337048237204 0.266045610348556 CTTNBP2 other 1 1 1 -0.909271302591148 -1.11337048237204 0.32924248203984 14.0502157558531 14.719283281899 0.954544829851281 0.340238213694802 42.8173985629472 30.4741340194841 1.40504069896034 0.160588461739427 RARB og 1 1 1 0.954544829851281 1.40504069896034 5.88545242765465e-12 852.4774473034 193.732792145926 4.40027440817189 1.30102956090755e-05 -1358.9444327355 374.067165684893 -3.63288884296316 0.000306756881868216 TM9SF3 other 5.39578278567379e-08 1 0.116168929493435 4.40027440817189 -3.63288884296316 0.0366105919791798 41.2691412440576 46.8917726451323 0.880093434649493 0.379199470023282 -191.174747424722 96.7999292873172 -1.97494718056338 0.0487821131976689 NFKB2 other 1 1 1 0.880093434649493 -1.97494718056338 3.49222045795089e-11 101.38474998043 14.8413251762008 6.83124645385497 2.25266927765344e-11 218.424337517226 115.653698337414 1.88860659587369 0.0594743535545851 UBE2T other 3.08258299823325e-07 1 2.64508426582067e-07 6.83124645385497 1.88860659587369 0.38185807928725 39.64119820809 46.6013936832825 0.850644048920594 0.395342742228493 -396.102301642635 359.434554531746 -1.10201508633097 0.270944225138563 PPP1R12B other 1 1 1 0.850644048920594 -1.10201508633097 3.1281655723018e-06 578.555084210164 159.683386511959 3.62313886777968 0.000318533833740763 -1108.1288809613 433.827485691285 -2.55430768568189 0.0109132398929341 DNAJC10 other 0.0199545681857132 1 1 3.62313886777968 -2.55430768568189 4.75839371137913e-22 582.943058625591 65.8316331245351 8.85505996065487 1.19658436866312e-17 -1238.50889504248 380.893370260851 -3.25158953067181 0.00121908673041616 GTF3C1 essential 5.86947864298616e-18 1 1.59995295933945e-13 8.85505996065487 -3.25158953067181 0.000202185080185793 101.934738417901 28.9381380731124 3.52250508171472 0.000463552561715002 -222.405721123542 165.549191102132 -1.34344190776707 0.17969111999214 IL4R other 1 1 1 3.52250508171472 -1.34344190776707 3.60897481759079e-13 208.650647346952 64.0420593517256 3.2580252643192 0.0011928314293212 -666.720704617054 127.251778500096 -5.23938221120071 2.31827327800512e-07 USP33 other 3.47183377452234e-09 0.00301839180796267 1 3.2580252643192 -5.23938221120071 0.00932181230961993 91.8550804271512 30.2150194357951 3.04004704092072 0.00247860629778576 150.809464931422 116.022304830546 1.29983165867705 0.194206153169184 SNRPA other 1 1 1 3.04004704092072 1.29983165867705 0.257241550594282 -35.1451176114568 28.9467812829251 -1.21412868905697 0.225234250516702 -152.70809467909 113.112216661277 -1.35005836846418 0.177568142075843 SPAG6 other 1 1 1 -1.21412868905697 -1.35005836846418 7.8766453871921e-12 98.3103537117176 16.9522560655259 5.7992489808859 1.12839527941496e-08 -122.775956418441 54.346210013406 -2.2591447754711 0.0242679123330797 EXOSC5 essential 7.1795622704256e-08 1 0.0001205464676999 5.7992489808859 -2.2591447754711 1.03011971889606e-10 -63.175947521865 59.7624400353442 -1.05711794037362 0.290929566608543 -1011.93786848072 147.486092030662 -6.86124267412515 1.87363230992871e-11 DYNC1I2 essential 8.87551149800847e-07 2.70945968338791e-07 1 -1.05711794037362 -6.86124267412515 0.391037776861321 -21.8622317129561 16.3914746679332 -1.33375624560037 0.182840869031263 0.343489023694138 60.411720725154 0.0056858010262091 0.995465492159093 APBB1IP other 1 1 1 -1.33375624560037 0.0056858010262091 8.25014219754483e-15 121.371040218123 29.0872008412438 4.17266140116262 3.50721463210511e-05 -523.941716441905 92.9013375118574 -5.6397650504766 2.74680150559291e-08 LRCH4 other 8.45887079514271e-11 0.000370351246999092 0.302251756994818 4.17266140116262 -5.6397650504766 1.56759545089137e-15 44.3346591417987 12.5356917659509 3.53667431918032 0.000440381968274825 -108.858338772445 24.6195523163091 -4.42162137531366 1.1869811919294e-05 FAM76B other 1.64597522343594e-11 0.142627660022237 1 3.53667431918032 -4.42162137531366 2.94256007806888e-14 42.3169967598653 11.7203099103635 3.61056977874339 0.000333668067380793 -155.048545531924 28.4309236344782 -5.45351770928387 7.49359724144052e-08 SIRT6 other 2.95285903834212e-10 0.000996273753249518 1 3.61056977874339 -5.45351770928387 6.75811774649088e-89 327.039337256413 13.722890083942 23.8316663076026 9.98827696082485e-86 33.8933269708232 59.0217211657422 0.574251755140205 0.566042471508522 POLD3 essential 1.05338781314553e-84 1 1.55707249542299e-81 23.8316663076026 0.574251755140205 0.675912919097026 261.782575913676 312.094465371087 0.838792753349249 0.401954037766598 -464.345047639223 1945.24698638712 -0.23870750135521 0.811422294930407 ACTN2 other 1 1 1 0.838792753349249 -0.23870750135521 1.34255232598746e-20 573.775425649997 151.382369904448 3.79023941831642 0.000167227260976544 -1510.33488209338 253.86821611152 -5.94928701681155 4.8098756164767e-09 CAPZB other 1.60810917606778e-16 6.63474242536795e-05 1 3.79023941831642 -5.94928701681155 0.000200890682308631 96.9000573788225 23.8737564680947 4.05885255252232 5.65620287461323e-05 -94.5912622571329 146.310288805255 -0.646511349472067 0.518221410953629 GPR137B other 1 1 0.478401639134787 4.05885255252232 -0.646511349472067 0.261646937167105 1.01554584668132 2.39338731192169 0.424313207320351 0.671508937688035 -6.30225115872596 5.54587699933454 -1.13638495038425 0.25630711893488 NAALAD2 other 1 1 1 0.424313207320351 -1.13638495038425 1.19660202121116e-10 44.4231193440948 31.9329846402008 1.39113583790004 0.164760326846112 -369.971099918779 66.021368132658 -5.60380843934329 3.35502938182627e-08 JADE1 other 1.02740249541191e-06 0.000450781747742177 1 1.39113583790004 -5.60380843934329 1.40774212251392e-06 190.262161375181 45.4758709159839 4.18380467581782 3.44663259488285e-05 -1445.08640214663 569.75568076684 -2.53632644820965 0.011538512892539 FGFR1 og 0.00927702058736671 1 0.297272061308645 4.18380467581782 -2.53632644820965 8.41348169326535e-09 51.6801123747735 8.46568537972229 6.10465781052553 1.95795647550411e-09 34.067989641509 16.6471177024297 2.04647977208311 0.0411884117907962 SMC1B other 6.53727527566718e-05 1 2.15296894046432e-05 6.10465781052553 2.04647977208311 0.254413317376042 -100.467157508698 324.260020020824 -0.309835167166912 0.756804522746237 -999.731823525757 637.508129893609 -1.5681867832691 0.117416878484671 FBLN1 other 1 1 1 -0.309835167166912 -1.5681867832691 0.00524996462877694 -34.8317519722377 10.6983983011258 -3.25579128686695 0.00120113705972485 -23.0387217540492 41.1947611579692 -0.559263389480591 0.576212141884582 ITGA8 other 1 1 1 -3.25579128686695 -0.559263389480591 0.872970340750294 1.21741500477134 5.57790434037747 0.218256701886887 0.827312333303965 -9.62681191685251 24.0073388522629 -0.400994544880392 0.68858423912921 CST7 other 1 1 1 0.218256701886887 -0.400994544880392 0.0013783181256941 216.696420772482 63.8288299747545 3.39496150655103 0.000736458941291679 340.342442803347 152.261593836145 2.23524812941079 0.0258061032911261 MAP2 other 1 1 1 3.39496150655103 2.23524812941079 2.02168909760064e-29 158.229633508703 19.154812586895 8.26056808391625 1.12092146334316e-15 -177.673088789297 39.9902022342696 -4.44291548585967 1.07682673393323e-05 PIAS2 other 2.75131669292472e-25 0.129736084904276 1.44957563639538e-11 8.26056808391625 -4.44291548585967 0.455668442315899 17.8182645894538 28.7281687960668 0.620236699245978 0.535359795454417 -97.947936280759 108.532012233074 -0.902479685628739 0.367198607713902 AMPH other 1 1 1 0.620236699245978 -0.902479685628739 1.41790932110456e-28 291.91317280011 25.2736891667407 11.5500816233927 9.67715873007688e-28 303.590507487816 107.644206326913 2.82031442143592 0.00497336099896499 MCCC1 other 1.91375221069482e-24 1 1.40754273728968e-23 11.5500816233927 2.82031442143592 2.66908544848639e-05 110.155897296235 27.4766186209311 4.00907763855339 6.94828937699227e-05 252.030752810426 117.583161045965 2.14342555999072 0.0325225433322077 LAMP3 other 0.155661063355726 1 0.582266649791952 4.00907763855339 2.14342555999072 0.0239192050931844 -90.4594334662254 73.7375796965773 -1.22677519167915 0.220437778736906 -487.354947741607 179.824664972572 -2.71016741677757 0.0069371575963183 FAP other 1 1 1 -1.22677519167915 -2.71016741677757 0.000781364872767698 -190.489442641861 132.159714871735 -1.44135785119343 0.150063239930883 -1902.22743587055 507.438130222558 -3.7486884066758 0.000196933846766608 NEBL other 1 1 1 -1.44135785119343 -3.7486884066758 4.77134120106887e-45 202.223172357687 13.4406621830761 15.0456256993289 1.36808799301905e-42 -156.978814413495 93.9920437783565 -1.67012874817009 0.0955086729719124 ACER3 other 7.12504381555614e-41 1 2.07689438220222e-38 15.0456256993289 -1.67012874817009 1.70272330505391e-34 535.926184557769 69.4932784675199 7.71191396313606 5.91059356345188e-14 -795.125115815081 141.812071727469 -5.60689302489801 3.27446197476875e-08 UBE2K other 2.42059145046463e-30 0.000440153178648415 7.39947208208541e-10 7.71191396313606 -5.60689302489801 8.48872474373545e-32 190.218829754807 24.742501868782 7.68793838083162 7.13277684752677e-14 -329.039250204291 53.2154233664062 -6.18315573548565 1.2419503776227e-09 PIK3C3 essential 1.18095138634848e-27 1.73624662791654e-05 8.9138312263542e-10 7.68793838083162 -6.18315573548565 4.11804106979097e-09 100.865319945719 26.7790120429064 3.76658107416767 0.000183477401261257 -137.39173568184 54.5501264368159 -2.51863276322516 0.0120657859242972 N4BP2 other 3.26190033138143e-05 1 1 3.76658107416767 -2.51863276322516 1.98893646296901e-22 57.2718808107231 5.78441205761487 9.9010720951886 2.35040148492145e-21 -13.2064585263407 20.6361159865425 -0.639968225365332 0.522463681047055 TIGAR other 2.46986129971492e-18 1 3.27081870641668e-17 9.9010720951886 -0.639968225365332 2.05825379883273e-43 257.148737087772 17.3086534028032 14.8566575979923 4.49364913846678e-42 7.12517462786292 63.6860082188378 0.111879749212408 0.910960559641059 TULP3 other 3.05691854202637e-39 1 6.81686574305411e-38 14.8566575979923 0.111879749212408 2.39426611737307e-10 152.479575579991 38.9607156884197 3.9136749129409 0.00010245425620737 -242.449334162035 82.8377239209299 -2.92679859713984 0.00356815029277117 SYNJ2 other 2.03033766753236e-06 1 0.84596479350425 3.9136749129409 -2.92679859713984 0.283256112472655 38.112897752945 24.0741894869621 1.583143547723 0.113972050827277 38.4547658620482 110.496342937143 0.348018448754667 0.727961449559034 ADCY2 other 1 1 1 1.583143547723 0.348018448754667 9.25765810952655e-22 403.712258827858 51.0758571663004 7.90417001741921 1.52157144692769e-14 -331.444107940568 106.19444052669 -3.12110602303391 0.00189791786563885 PPP2R5C other 1.13526661397124e-17 1 1.92874396612554e-10 7.90417001741921 -3.12110602303391 5.05244912214401e-37 2262.37476431715 208.408541786226 10.8554800342002 5.74035227649982e-25 -1493.87864644296 426.642209369592 -3.50147878863256 0.000500971798911951 GNB1 other 7.29321030781487e-33 1 8.223054636086e-21 10.8554800342002 -3.50147878863256 0.397179517734458 28.6654787121801 21.0956034568466 1.35883663014516 0.174766703166947 32.505826024133 72.3311628948499 0.449402784680619 0.653321774937527 EDN1 other 1 1 1 1.35883663014516 0.449402784680619 1.42389202087097e-13 140.831908999618 18.57870466999 7.58028675847907 1.52376495742465e-13 -41.1388873114253 71.5366577140625 -0.575074215458325 0.565481965977901 MLLT10 og 1.39299356401807e-09 1 1.89007805318954e-09 7.58028675847907 -0.575074215458325 1.53084688105648e-07 14.7154273558613 5.07932855688471 2.89712059203484 0.00391911611506002 -62.6619242322231 16.2494131906637 -3.85625766893702 0.000129043013878019 ZCWPW1 other 0.00109409626589107 1 1 2.89712059203484 -3.85625766893702 0.874073742793739 -1.33235773998519 10.606199253813 -0.125620659022241 0.900078619260501 -23.1160904778393 44.5716598865423 -0.518627543526122 0.604231388194935 ADCYAP1R1 other 1 1 1 -0.125620659022241 -0.518627543526122 7.38558867352012e-50 602.272013301601 39.2001339011997 15.3640294908066 2.55105080386535e-42 -500.781209545526 173.412367779792 -2.88780561592611 0.00408692284911809 VDAC3 other 1.11662715154951e-45 1 3.87121959486567e-38 15.3640294908066 -2.88780561592611 7.28091099534334e-37 620.47563033118 217.506082566953 2.85268174116549 0.00450136038489978 -3914.94875500842 444.693710292242 -8.80369716143638 1.79536563581837e-17 PCM1 other 1.0497617473086e-32 2.73900981400451e-13 1 2.85268174116549 -8.80369716143638 2.92144804346659e-12 76.6323298717154 22.9882100758547 3.33354922453075 0.000916585438125108 -396.738622893618 67.637004296922 -5.86570364872994 7.82431908432038e-09 TNRC6C other 2.71285665316308e-08 0.00010735748215596 1 3.33354922453075 -5.86570364872994 2.25882744621232e-11 101.603082624243 19.8236499001801 5.12534690311092 4.15544883416166e-07 -466.680223424497 112.24215247932 -4.15779823458463 3.74190147222065e-05 CBFA2T2 other 2.01193760634132e-07 0.434883789101484 0.0040997658197839 5.12534690311092 -4.15779823458463 0.460077201629611 -2.66044371098164 16.0561737787285 -0.165695996296842 0.86845879142218 -44.3727577132817 36.1197713277942 -1.22848944171296 0.219803418635959 BRINP1 other 1 1 1 -0.165695996296842 -1.22848944171296 4.9727290864687e-09 132.439243677142 21.9897490024102 6.02277195899901 3.22614427778397e-09 -92.5834335180232 120.428303568089 -0.768784669176026 0.442366847605203 ITCH other 3.91900779304598e-05 1 3.5184329493512e-05 6.02277195899901 -0.768784669176026 1.70127219605431e-12 5.89772638128655 4.14603928183418 1.42249650338031 0.155454252154549 -61.74556888016 9.58676599271809 -6.4407088821257 2.61434652454575e-10 PKD2L2 other 1.59385230729393e-08 3.7087119797206e-06 1 1.42249650338031 -6.4407088821257 0.0177189705099398 101.819346778511 35.7641281077775 2.8469685174953 0.00458588530205198 129.04083526682 217.692558440874 0.592766405020997 0.553591759949789 TP53INP2 other 1 1 1 2.8469685174953 0.592766405020997 1.4244444650601e-17 327.207182713984 82.0147698256601 3.98961288813628 7.57003272171435e-05 -845.600118176581 153.393484084857 -5.51262084710715 5.57934974953956e-08 SDF4 other 1.58953757856057e-13 0.000744675811071045 0.632551934226451 3.98961288813628 -5.51262084710715 1.19883371309528e-18 19.1827640495586 2.04543980452053 9.37830778845881 2.03397198666407e-19 -0.0464658218850946 17.1135912300112 -0.00271514150715543 0.997834670460843 MYH7B other 1.3739833185785e-14 1 2.78064310296845e-15 9.37830778845881 -0.00271514150715543 0.124066651632892 583.883816599838 294.836808344175 1.98036269582137 0.0481661467937972 -413.585933473334 1686.41016546703 -0.245246347503364 0.80635817952158 BPIFB2 other 1 1 1 1.98036269582137 -0.245246347503364 0.0351586379909882 18.6740172193724 11.9376452666909 1.56429654275937 0.118334839881476 -23.1213946548311 21.2278688646401 -1.08919999469872 0.276552438166424 TP73 other 1 1 1 1.56429654275937 -1.08919999469872 2.01121549662167e-26 169.201954127742 42.3092459347822 3.999172057771 7.23513918323092e-05 -626.923448875886 84.1248833971866 -7.45229501140506 3.63160430986963e-13 TOLLIP other 2.64897193060041e-22 5.36061112179856e-09 0.605508798244596 3.999172057771 -7.45229501140506 1.36814065667915e-11 64.5004765624953 12.30204202068 5.24307074013146 2.2657417911117e-07 -179.925623571059 48.4622032730923 -3.71270003051964 0.000226235096937594 UBE2D4 other 1.2314634050769e-07 1 0.00226823410708192 5.24307074013146 -3.71270003051964 1.96201548616733e-07 10.4094934379981 12.0445919653975 0.864246249927197 0.387848827258555 -119.850515147798 26.4119942725679 -4.53773062007203 7.06057657081182e-06 CLUL1 other 0.00138910696420647 0.0860472466684837 1 0.864246249927197 -4.53773062007203 0.0867590588067829 -7.6430224555581 3.9342778847483 -1.94267478796737 0.0525917971161626 -47.1621015077741 40.4308540478781 -1.16648788699652 0.24394886697786 RUNX1T1 other 1 1 1 -1.94267478796737 -1.16648788699652 6.4662996069435e-31 117.523990219382 19.9541520725421 5.88970104027126 6.93605092165706e-09 -313.051813648078 43.764855493499 -7.1530411815156 2.88587786969216e-12 THOC1 essential 8.92414008754273e-27 4.22001920885085e-08 7.47498207826981e-05 5.88970104027126 -7.1530411815156 0.000183754326784163 23.0737299208901 11.1063913832254 2.07751817172045 0.0382275117774747 -79.3172427234431 27.5232395955884 -2.88182800749068 0.00411164777532009 FKBP7 other 0.963975198309718 1 1 2.07751817172045 -2.88182800749068 0.0208263856439451 -3.84638256989664 22.7439118465166 -0.169117018912723 0.865768163598139 -152.388617853647 56.0498104470709 -2.71880701536986 0.00676329988645913 OSBPL6 other 1 1 1 -0.169117018912723 -2.71880701536986 0.0118338635561907 49.6725598042405 16.7357704784428 2.96804738498435 0.00312941894108375 66.2146070253176 84.0753562381119 0.787562610353855 0.431296859678009 SLC1A3 other 1 1 1 2.96804738498435 0.787562610353855 3.88083331596186e-15 945.8569339985 197.479997625742 4.78963411672233 2.15643120384505e-06 -2393.32348094678 453.840952571715 -5.27348505546906 1.93337438337691e-07 XRCC5 essential 4.02481223198405e-11 0.00252479360725191 0.0203394591146665 4.78963411672233 -5.27348505546906 0.462171194994362 34.724815845976 35.4777886816043 0.97877621848459 0.328132942428494 -100.634676113198 137.314221886686 -0.732878755969236 0.463953356815568 LXN other 1 1 1 0.97877621848459 -0.732878755969236 0.243868992421068 5.07516103780309 6.87386858852941 0.738326747513348 0.460634895457688 23.3966419888301 14.0241449087712 1.66831148287673 0.0958303951540567 SP140 other 1 1 1 0.738326747513348 1.66831148287673 1.80880901307902e-15 50.7051659408712 15.303875506446 3.31322389021749 0.00098371046813688 -192.725919775864 31.6728877599509 -6.08488626728749 2.20303180078052e-09 MKNK1 other 1.89563184570682e-11 3.06221420308492e-05 1 3.31322389021749 -6.08488626728749 0.207855727503481 385.908447082739 503.917235300607 0.765817122433864 0.444117268128615 -1526.17307073627 1140.77187278422 -1.33784247941828 0.181506779496141 TNS1 other 1 1 1 0.765817122433864 -1.33784247941828 8.8702439103616e-26 481.488698906128 61.1344381864054 7.87589962695033 1.84803582524255e-14 -834.256415470118 159.027841793064 -5.24597709472597 2.23057144289164e-07 SAR1A other 1.15898606932785e-21 0.00290598847579923 2.3383197296794e-10 7.87589962695033 -5.24597709472597 0.382993826242569 22.9579030113784 32.6174688510976 0.703852991051631 0.481829980394076 -50.7468879768253 62.5241872560461 -0.811636107623584 0.417360745423772 CDC14A other 1 1 1 0.703852991051631 -0.811636107623584 2.55705111534736e-07 24.1639513020152 25.0772924037822 0.963578958722465 0.335692385586853 -359.764095763245 71.4336433706737 -5.03633972435658 6.49737865780727e-07 RAPGEF3 other 0.00179402706252771 0.00832119284705377 1 0.963578958722465 -5.03633972435658 0.00801464750735911 125.135140351793 57.8794143294033 2.16199734917192 0.0310668927411671 -315.768821102385 213.481576580047 -1.47913851003431 0.139699640553418 CEACAM1 other 1 1 1 2.16199734917192 -1.47913851003431 0.000320133665720711 74.5656306043887 18.7135541114491 3.9845787796541 7.68806688640452e-05 21.6283919902218 54.7725215362662 0.394876689690123 0.693089814955745 SENP1 other 1 1 0.642030465683641 3.9845787796541 0.394876689690123 0.242129873361977 14.7051859587906 11.6046983404493 1.26717520157626 0.205650210882671 -19.9202665860789 30.0236473375612 -0.663485897036818 0.507308438211165 DUSP13 other 1 1 1 1.26717520157626 -0.663485897036818 1.58644646106973e-15 190.536090015603 54.0679358307825 3.52401265348704 0.000461746097105396 -1057.57751818292 171.209327944959 -6.17710221094327 1.29986272593963e-09 CIC og 1.66497556089268e-11 1.81642817322804e-05 1 3.52401265348704 -6.17710221094327 0.234198179886303 213.473854043258 179.410976206079 1.18985949777149 0.23463535314581 -454.040534115514 584.12522744886 -0.777299991131209 0.437329258049934 LIPE other 1 1 1 1.18985949777149 -0.777299991131209 5.12941461725778e-35 908.427791760247 127.604777424124 7.11907351823419 3.48019455415875e-12 -1250.76146107096 266.796690444075 -4.68806962705987 3.49674109468266e-06 FDFT1 other 7.3186487759034e-31 0.0432651775645086 4.17901762063382e-08 7.11907351823419 -4.68806962705987 3.59971034630114e-08 223.160591654685 64.9396404818669 3.43643096880091 0.000635519402333943 -719.414167148056 207.516615170977 -3.46677863146194 0.000569333077373451 PAFAH1B3 other 0.000269258333903325 1 1 3.43643096880091 -3.46677863146194 3.40326451648315e-13 317.477468496731 45.8831673128829 6.91925791285972 1.3021532355971e-11 -494.945505642359 276.658005265402 -1.78901566635511 0.0741778976090796 KIF22 other 3.27700340292163e-09 1 1.53979620109357e-07 6.91925791285972 -1.78901566635511 0.731235414720928 18.3256841324426 33.1282065849772 0.55317465149933 0.580372758562681 -44.975908131932 117.210256090357 -0.383719903292935 0.701337091105166 SCGN other 1 1 1 0.55317465149933 -0.383719903292935 7.05169064254052e-09 166.867486240172 28.6150481787575 5.83145920977506 9.46697849113336e-09 -45.1418267825887 101.820114558091 -0.443348811563494 0.657691023014769 CARMIL1 other 5.51230657527393e-05 1 0.000101400806618529 5.83145920977506 -0.443348811563494 1.06225519948767e-07 478.750046064085 105.834344420157 4.52357926613569 7.47848399478849e-06 -361.727615200413 208.467613238369 -1.73517415766065 0.0832794298035996 PGM1 other 0.000767266930589945 1 0.0680242904165961 4.52357926613569 -1.73517415766065 5.98842494026625e-26 535.850644003744 52.1703351665083 10.2711750325833 9.9175904773574e-23 -338.812974551884 153.718110016624 -2.20411878935567 0.027936335673358 DDX1 essential 7.84723204172489e-22 1 1.39699179464056e-18 10.2711750325833 -2.20411878935567 4.22154482182222e-38 810.853163281242 63.6606251935133 12.7371222135573 1.11494149682935e-32 -570.233574138654 208.796258393689 -2.73105264685093 0.00651963430986096 DNM2 other 6.13137169921459e-34 1 1.6543501929954e-28 12.7371222135573 -2.73105264685093 0.151952112352519 132.59453608654 83.7501500716439 1.5832155043676 0.113962180420925 -57.5391435275025 196.577210093407 -0.292705057214729 0.769860878767118 EPB41L2 other 1 1 1 1.5832155043676 -0.292705057214729 0.0345758903826657 2.93579598118571 20.7599122540607 0.141416589109689 0.887593785926793 -104.036599967303 47.5554186388662 -2.18769181189115 0.0291216095712807 RIMS1 other 1 1 1 0.141416589109689 -2.18769181189115 0.131520411690029 35.3749640441589 27.2026330671452 1.30042426249112 0.194012377485696 -49.0992415817189 64.3164561764521 -0.763400916353588 0.445558958523242 MOXD1 other 1 1 1 1.30042426249112 -0.763400916353588 2.84743602263032e-20 187.951141972887 28.3165909315626 6.6374918657101 7.80464627236738e-11 -229.236993214921 66.9502387956701 -3.42399067334987 0.000664128102087113 STX7 other 3.38987258494139e-16 1 9.01670783846603e-07 6.6374918657101 -3.42399067334987 3.90492561209011e-28 99.9180694241184 14.5063850095291 6.88786829788974 1.64399554501124e-11 -191.019415306679 31.1275952060576 -6.13665829442249 1.67418591299916e-09 RABL2B other 5.24704854496548e-24 2.33381516272083e-05 1.93859954667725e-07 6.88786829788974 -6.13665829442249 6.88538643633609e-32 390.023698757312 35.5554036716457 10.9694633861897 2.05449367598736e-25 -406.64951355741 115.164675342767 -3.53102643972286 0.000449332756084121 KEAP1 other 9.58583499666711e-28 1 2.94902022251226e-21 10.9694633861897 -3.53102643972286 2.43499173689387e-05 13.631667404195 3.22779273427611 4.22321645979296 2.82970041178472e-05 3.08666811222234 7.40003229661805 0.417115492000353 0.676760941697437 DDX43 other 0.142495716443029 1 0.245787777767621 4.22321645979296 0.417115492000353 0.00882667500043723 21.0346025811527 6.82186076657795 3.0834113009469 0.00215042880324008 16.1117841317168 26.0963901649065 0.617395127444994 0.537232945765946 PTPRH other 1 1 1 3.0834113009469 0.617395127444994 3.29489714220326e-34 250.758414477865 19.2364542505792 13.0355839600905 6.09413308924301e-34 -118.338934285819 117.625742584166 -1.00606322804843 0.314838264970702 SLC35C2 other 4.6751295550722e-30 1 9.07964888966316e-30 13.0355839600905 -1.00606322804843 0.0511591713688005 73.5124005753374 39.4625613529799 1.86283905694293 0.0630379096640016 -177.604199050107 137.161242298523 -1.29485703157721 0.195933348881638 CRYBG3 other 1 1 1 1.86283905694293 -1.29485703157721 2.54944799191573e-10 62.3240455216717 19.0789470314048 3.2666396850457 0.00115742279132298 -198.356453556099 46.5162982710587 -4.26423556750456 2.36800420178058e-05 RFX3 other 2.15759783555828e-06 0.278998255053787 1 3.2666396850457 -4.26423556750456 0.000480453020421407 227.936518299556 69.2891098016949 3.28964420169214 0.00107233606559363 -166.197830972735 168.930588089768 -0.983823195384954 0.325668030185085 RIF1 other 1 1 1 3.28964420169214 -0.983823195384954 2.73095801760093e-42 399.495903219122 29.3470352851091 13.6128198074519 2.10325243088957e-36 -507.042482902737 114.784313363653 -4.41734996746773 1.21196236639126e-05 RAB21 other 4.03799452482473e-38 0.145580919450918 3.15445799584818e-32 13.6128198074519 -4.41734996746773 0.260507485970947 -130.55945085508 84.3843993977864 -1.54719891101701 0.122403295524166 -236.867009170087 219.847444755096 -1.07741533877708 0.281777612838481 SLC4A4 other 1 1 1 -1.54719891101701 -1.07741533877708 2.27859260292368e-21 305.012087913956 105.891544877952 2.88041966207506 0.00412948024546561 -1978.99660769752 254.363509197321 -7.78019069615182 3.71403381639772e-14 SMARCA2 other 2.77213576071695e-17 5.53391038643261e-10 1 2.88041966207506 -7.78019069615182 2.74277396712521e-15 148.336462413533 24.5818683996066 6.03438518188094 2.99241132119403e-09 -189.523053501591 70.4159649933156 -2.69147846684458 0.00733752326980003 SESN1 other 2.85742191895105e-11 1 3.26681543934752e-05 6.03438518188094 -2.69147846684458 0.706456334826048 -30.6171235008844 47.5188288194536 -0.644315616809776 0.519646933078517 -114.731853573779 171.133935355691 -0.670421406106957 0.50287848196895 COL5A3 other 1 1 1 -0.644315616809776 -0.670421406106957 1.25566022515585e-22 663.727108981496 75.2949093918159 8.81503297291489 1.74333893679941e-17 -1551.08952668147 451.436112498803 -3.43590041588794 0.000637186150598413 SRCAP essential 1.56430150849916e-18 1 2.32578847558409e-13 8.81503297291489 -3.43590041588794 2.53026050572978e-35 423.892491222472 33.9800125646257 12.4747596963445 1.45841046678912e-31 9.77211544486357 81.0288868592611 0.120600391090609 0.904052417692555 PUM3 other 3.61953765344646e-31 1 2.15625987514771e-27 12.4747596963445 0.120600391090609 3.77980282010509e-18 30.2493343865832 3.2717231943726 9.24568876688968 5.35396211358993e-19 26.0866468986813 7.87242154232664 3.31367505645176 0.000982387722207872 CHRNA3 other 4.28138265433303e-14 1 7.28245926690502e-15 9.24568876688968 3.31367505645176 0.00681371908013824 1.15821810891598 1.88841917426673 0.613326810434295 0.53991708497168 -11.1486839660576 4.20460822102888 -2.6515393063969 0.008246654153205 KCNN2 other 1 1 1 0.613326810434295 -2.6515393063969 5.35845714857091e-12 42.0407280949129 11.5486480144932 3.64031599561723 0.000298247225654513 -182.925009787167 37.4912498603082 -4.8791387448736 1.40090000442665e-06 CNOT4 other 4.92227873667724e-08 0.01766534905582 1 3.64031599561723 -4.8791387448736 1.19616861291202e-40 299.654503703021 55.03102209541 5.44519240772042 7.85689394979749e-08 -1077.27828506882 107.825489995087 -9.99094263441699 1.09551952414349e-21 PSEN1 other 1.75633437433872e-36 1.69564511946929e-17 0.000807688698039182 5.44519240772042 -9.99094263441699 1.51093526738965e-09 70.3602664414017 12.7428804752312 5.5215354627365 5.21127093039739e-08 -113.911959142315 44.1544736709567 -2.57985091139797 0.0101454709441027 CPOX other 1.22573190130308e-05 1 0.000540825697156641 5.5215354627365 -2.57985091139797 1.76579770028763e-08 132.640296988555 29.5319257083117 4.49142051550073 8.65734031417512e-06 -346.323340193585 102.551679208476 -3.3770616226532 0.000785426926031226 CLDND1 other 0.000134642074646932 1 0.0784181885657982 4.49142051550073 -3.3770616226532 0.101457191409163 58.3644098334096 28.2809509792724 2.06373575896319 0.0395182379199306 14.1025786494884 59.0501704834581 0.238823673734169 0.811332585405869 MOK other 1 1 1 2.06373575896319 0.238823673734169 1.1556539997853e-21 12092.9700577264 1183.9632935816 10.2139737974004 1.61535512894139e-22 7003.64285616516 2466.98456490943 2.83894879432384 0.00469604647822968 HSP90AA1 other 1.41405823413729e-17 1 2.27005856270133e-18 10.2139737974004 2.83894879432384 1.2338557963749e-22 116.366339478532 11.2082667421603 10.3821886251883 4.08977182045426e-23 237.963565147773 74.1089370401864 3.21099687367982 0.00140282161485004 RBL1 other 1.53726093670348e-18 1 5.78007451384801e-19 10.3821886251883 3.21099687367982 1.65956183746075e-22 332.326853355101 31.8176664226703 10.4447274335089 2.43035575269429e-23 49.4724580952836 213.277443417535 0.231962917890154 0.816656689625013 DLGAP4 other 2.06383110106619e-18 1 3.44235588811619e-19 10.4447274335089 0.231962917890154 0.0020858211638138 -3.35092531329314 6.59202771527038 -0.508329979488823 0.611435066286613 -36.9956322480407 11.8630217472532 -3.11856734618283 0.00191684921330544 IGSF9B other 1 1 1 -0.508329979488823 -3.11856734618283 2.38721732892956e-06 -1.66253359839692 4.33026122249738 -0.38393378897315 0.701177261269157 -30.6341948508745 6.73218865235588 -4.55040647741716 6.6063611243483e-06 CROCCP3 other 0.0154118750755693 0.0806240311615466 1 -0.38393378897315 -4.55040647741716 9.58045149824433e-13 191.903907841659 25.5231473935609 7.51881830569506 2.37645105260657e-13 126.500516822991 58.4334875859631 2.16486336943165 0.0308437733741774 NDC80 essential 9.05735884644019e-09 1 2.93467940486385e-09 7.51881830569506 2.16486336943165 5.18871400009151e-20 80.627906011742 12.7823115207077 6.30777194571754 5.90506393108228e-10 -115.74892623851 25.9048892947848 -4.46822701773955 9.61686609002261e-06 AP4E1 other 6.14750006188649e-16 0.116229443564013 6.63256780739162e-06 6.30777194571754 -4.46822701773955 5.06895751402565e-121 273.474395726914 8.84818171401667 30.9074117785912 1.32416989661537e-121 -30.1391894481336 48.080289639232 -0.626851245578624 0.531021179797011 RSBN1 other 7.93190471794733e-117 1 2.07245830519272e-117 30.9074117785912 -0.626851245578624 5.11747964204347e-14 218.633083361317 29.1596423863836 7.49779714251264 2.66652002428225e-13 -359.326365683416 157.018435841509 -2.28843424504695 0.0224962360489494 MAGI3 other 5.08882175604803e-10 1 3.28888579794973e-09 7.49779714251264 -2.28843424504695 0.465420792058644 -10.3815452475811 8.4315510615533 -1.23127348358472 0.218759556296516 -13.6754233067728 26.0680929377236 -0.524603903302143 0.600075058634486 CXCL2 other 1 1 1 -1.23127348358472 -0.524603903302143 0.828086115766294 -7.52957781988215 25.1374497121889 -0.299536265854016 0.764646804264605 -46.5739210570548 76.9580360216105 -0.605185935929764 0.545311115383552 AFP other 1 1 1 -0.299536265854016 -0.605185935929764 0.0860641982935423 13.3563496544863 7.17597937124173 1.86125808945506 0.0632549648117525 25.8310861295053 15.3052652114614 1.68772548352586 0.0920456807014575 COL4A4 other 1 1 1 1.86125808945506 1.68772548352586 0.605198136847715 -15.5474257769151 24.5999778578047 -0.632009746788551 0.527645531121896 27.010036911929 56.6046633308369 0.477169818219102 0.633432486815334 TCF7 other 1 1 1 -0.632009746788551 0.477169818219102 9.01134687107778e-26 152.21469118411 15.0707775812772 10.0999892250557 4.70753650101287e-22 -8.41503721283743 43.1871719593727 -0.194850387998401 0.845584743068722 OSTM1 other 1.17688190136276e-21 1 6.58960959411782e-18 10.0999892250557 -0.194850387998401 0.0209056043422897 -1.54235311433601 13.8603804162516 -0.111277834230839 0.911437687934689 -73.0078274361269 28.4957137994412 -2.56206347207062 0.0106774637258338 CDH7 other 1 1 1 -0.111277834230839 -2.56206347207062 6.77136596806114e-11 241.568234820655 44.5622687318933 5.42091418805532 8.95907839693982e-08 -571.778653465141 155.408512860395 -3.67919776684804 0.000257467984184423 PCNP other 5.89311980200361e-07 1 0.000917947172550454 5.42091418805532 -3.67919776684804 5.41564930333543e-27 126.094557213318 28.9578009746783 4.35442447178842 1.599772618342e-05 -434.158420603104 56.7656492409211 -7.64825957967075 9.55370750898145e-14 EXD2 other 7.18440036580478e-23 1.41929878753428e-09 0.141691860806551 4.35442447178842 -7.64825957967075 1.22906050594288e-31 129.167272295414 15.4048284743768 8.38485624882226 4.47285036342703e-16 -144.138567363345 29.6413020789993 -4.86276098732743 1.52190918785177e-06 ARG2 other 1.70753376090645e-27 0.0191608366750538 5.82767673850908e-12 8.38485624882226 -4.86276098732743 0.922367917341125 -4.12526481358693 52.9516672602659 -0.0779062308521957 0.93793134164583 -46.4411461310264 118.171958158661 -0.392996332248919 0.694476428293333 MEF2C other 1 1 1 -0.0779062308521957 -0.392996332248919 0.104060275324964 -44.4846766064007 37.7379705631254 -1.17877765928059 0.239010709225327 450.711110641933 265.322469702284 1.69872951637934 0.0899515492401222 PTPRC other 1 1 1 -1.17877765928059 1.69872951637934 0.400496583777954 42.7153474241922 32.0787131038672 1.33157920911244 0.183556179136668 -44.4374855178046 229.654659782635 -0.193496990480681 0.846641987488301 CACNA1S other 1 1 1 1.33157920911244 -0.193496990480681 0.00779278137090205 -28.6667092569603 94.4953427311545 -0.303366371594831 0.761726228060618 2104.1703193796 677.480575796688 3.10587549599513 0.00199568654214016 PKP1 other 1 1 1 -0.303366371594831 3.10587549599513 7.35323666433828e-16 103.678262484446 18.1304910761093 5.71844756158114 1.77173925828625e-08 -335.591998866264 62.2831959030669 -5.38816279415969 1.06012115787569e-07 UBA5 other 7.80766669019438e-12 0.00140158618282745 0.000187751209200594 5.71844756158114 -5.38816279415969 0.0532407478139994 91.3744055616027 40.6813212957085 2.24610220738435 0.0251009151858142 -32.3762339305077 102.128995202834 -0.317013144662853 0.751356152221615 STK17B other 1 1 1 2.24610220738435 -0.317013144662853 0.13633733571231 8.10961125305823 17.5386602114932 0.462384877480206 0.643990902402987 -60.9724972818113 36.5499740507992 -1.66819536443633 0.095854512261417 CDC14B other 1 1 1 0.462384877480206 -1.66819536443633 2.36506026783106e-13 24.3414541815899 11.5335027167564 2.11049971369283 0.0352736843758789 -152.917836814653 23.8525857956741 -6.41095427240372 3.15283888820023e-10 ZNF510 other 2.29387195376935e-09 4.46441986569153e-06 1 2.11049971369283 -6.41095427240372 0.0102516785098122 -1013.4694911158 461.681966497435 -2.1951680261729 0.0285740490769142 -3204.27689127094 1209.51576247675 -2.64922292927335 0.00830265386523073 LRP2 other 1 1 1 -2.1951680261729 -2.64922292927335 0.00012300187458343 10.6117456301608 10.4942058665446 1.01120044385549 0.312375059064308 -129.500501186987 35.7332125782569 -3.62409343697762 0.000317492808758413 ZNF506 other 0.661750085258855 1 1 1.01120044385549 -3.62409343697762 1.78194527974508e-13 169.2131115234 21.5745783997478 7.84317117990025 2.37066900773689e-14 181.728569992843 135.360922363011 1.34254825410751 0.179983436599419 JMJD4 other 1.73632748058361e-09 1 2.99296962226782e-10 7.84317117990025 1.34254825410751 1.12173310449503e-32 62.9853949232075 4.90006221961246 12.8539990106879 3.51459399165324e-33 68.9065269161739 52.5356100500175 1.31161562320434 0.190207223266697 DUSP12 other 1.57278198581249e-28 1 5.22444396859255e-29 12.8539990106879 1.31161562320434 5.15512466394167e-05 232.873816169695 76.3426561633454 3.05037613141767 0.00239651690415355 -393.815322190783 175.270597913232 -2.24689894870868 0.0250451615859641 AACS other 0.29074903104631 1 1 3.05037613141767 -2.24689894870868 2.05399025584423e-41 77.7565386745567 26.5830425053276 2.92504285989736 0.00358722611794873 -787.946775217452 62.1642497343796 -12.6752398457997 1.86628490766743e-32 KIAA0141 other 3.02573304588414e-37 2.92297542238873e-28 1 2.92504285989736 -12.6752398457997 0.00588812207503203 -55.4528548585523 59.2482450018495 -0.935940884946403 0.349718914491677 -601.506703276759 186.883386340113 -3.21862052618237 0.00136484657309178 CADPS2 other 1 1 1 -0.935940884946403 -3.21862052618237 0.0852559435698234 0.208289327245298 11.789181221863 0.0176678365804596 0.985910389429392 -58.1534561967536 28.1123081760915 -2.06861193440569 0.0390596689527328 PCDHB4 other 1 1 1 0.0176678365804596 -2.06861193440569 5.40355503380019e-05 28.8328271318228 38.7399914022691 0.744265191812457 0.457056168531688 -407.292530373639 104.488552594922 -3.89796317643156 0.000109852344939839 PCDHA6 other 0.304004006201599 1 1 0.744265191812457 -3.89796317643156 0.0145200677015208 45.7405243578273 82.6076813875852 0.553707882723622 0.580007972119621 -504.082895763781 204.12325762701 -2.46950250365336 0.0138382930015751 PCDHGA2 other 1 1 1 0.553707882723622 -2.46950250365336 3.34387277237083e-19 136.444626689186 18.5842284074138 7.34195812158411 7.77629543031916e-13 -149.765885951869 41.8199967485561 -3.58120271630676 0.000372829389336817 HSPB11 other 3.88691771060385e-15 1 9.47152783412874e-09 7.34195812158411 -3.58120271630676 2.68403940919881e-18 195.816732904129 28.5369326670757 6.86187037649114 1.85625878499214e-11 -182.038314181632 61.6059658954556 -2.95488126085951 0.00326335700527729 PHLPP1 other 3.05175280825905e-14 1 2.18444533817874e-07 6.86187037649114 -2.95488126085951 6.974076758532e-11 165.242510511565 125.854965701344 1.31295979932717 0.189751089891603 -1479.51004831276 262.268086207512 -5.64121266032398 2.72045444785234e-08 ATP8B1 other 6.06674937224699e-07 0.000366853282292888 1 1.31295979932717 -5.64121266032398 6.0516345385639e-05 154.201236355323 35.49595378962 4.34419193999557 1.67076778079687e-05 41.2552816566018 68.3569807219205 0.603526972971939 0.546412068439566 IL12RB2 other 0.338467919741879 1 0.147762702533676 4.34419193999557 0.603526972971939 2.56926700306798e-05 72.2085088546075 29.0464950294837 2.48596289436341 0.0132186824234522 -256.261672563651 89.253987185461 -2.87115097761587 0.00424882560773331 SMARCD3 other 0.150122270989262 1 1 2.48596289436341 -2.87115097761587 1.45485265031766e-24 91.4855440591983 9.36716333749413 9.76662205654163 7.48967137111586e-21 -174.630862654649 48.1439498552153 -3.62726496641471 0.000313712187087603 WDR70 essential 1.86846725880298e-20 1 1.03814334875037e-16 9.76662205654163 -3.62726496641471 0.00208089151452066 -6.04708491432853 13.7806538096053 -0.438809725421998 0.660973956563847 -119.782965632458 34.1846066970351 -3.50400303546119 0.000496136946371628 STRADB other 1 1 1 -0.438809725421998 -3.50400303546119 2.78768811029486e-08 394.242666609906 189.308091177776 2.0825452528581 0.0377636369904662 -2328.39071226957 473.022346441248 -4.92236937596514 1.13816907569433e-06 BZW1 other 0.000209996545348512 0.0144183258508958 1 2.0825452528581 -4.92236937596514 3.56686854911726e-05 427.386653587219 548.128344017935 0.779720038658017 0.435896649906594 -3673.99552537921 1111.31756438545 -3.30598169517001 0.00100920639481864 PGR other 0.205380291058172 1 1 0.779720038658017 -3.30598169517001 0.0140288192804562 -43.8886385087613 34.4630958416653 -1.27349669079064 0.203388733152989 -453.965357218824 161.841588298762 -2.80499815894539 0.00521266112140196 C1QTNF3 other 1 1 1 -1.27349669079064 -2.80499815894539 2.30010550132622e-18 422.737100528624 45.3595368593426 9.31969613886287 2.92454670799391e-19 311.852010834174 92.7229560260511 3.36326648976287 0.000824684991694114 ME2 other 2.62120022931136e-14 1 3.98878925503289e-15 9.31969613886287 3.36326648976287 3.89479207232483e-21 147.125662370094 16.3420055391437 9.00291350518068 3.82467629088164e-18 -190.974339305407 75.0973347095036 -2.54302419711893 0.0112697222055796 C5orf22 other 4.71931955403599e-17 1 5.14992662567212e-14 9.00291350518068 -2.54302419711893 2.48299389142746e-12 55.9869303441492 28.0530188520451 1.99575420525794 0.0464597352354659 -393.848736547155 63.9149017957496 -6.16207997636862 1.40000799651765e-09 CCNT2 other 2.30968091780583e-08 1.9551111671369e-05 1 1.99575420525794 -6.16207997636862 9.78441881813188e-07 24.9589165907398 11.3245886991975 2.20395788789296 0.0279477174847696 -88.336101217593 27.1016897829058 -3.2594314939473 0.00118651716924294 FAM135A other 0.0065359917705121 1 1 2.20395788789296 -3.2594314939473 0.122992987753896 -32.9494765307518 77.9156133157714 -0.422886699193604 0.672548168471151 -344.114031913834 173.775585423557 -1.98022081798831 0.0481915619982413 EPB41L3 other 1 1 1 -0.422886699193604 -1.98022081798831 0.000528879011510822 95.9842542631609 66.545806001784 1.44237871670812 0.149773166680043 -505.988635990872 165.244392137892 -3.06206237588164 0.00230724239025275 COBLL1 other 1 1 1 1.44237871670812 -3.06206237588164 0.171356261358369 52.2559292114083 31.5523368592418 1.65616668725766 0.0982799501667043 216.577820898473 194.34459394194 1.11440105693486 0.265612261281772 KCNK2 other 1 1 1 1.65616668725766 1.11440105693486 3.12269792265812e-09 204.528483710761 39.4993422369261 5.1780225220955 3.18577921114926e-07 1079.87336108259 267.163519473397 4.04199406869289 6.08248965936693e-05 SERTAD4 other 2.49003932352759e-05 0.697114139860044 0.00316284160082899 5.1780225220955 4.04199406869289 1.13430242512497e-07 136.992180344687 26.9445350776389 5.08422876661086 5.11572790810388e-07 -380.449423079882 173.813895000273 -2.18883204406232 0.0290413463071275 TRAF5 other 0.000817378327545056 1 0.0050134133499418 5.08422876661086 -2.18883204406232 9.00793903631521e-26 96.047976750652 12.6632589757654 7.58477552535774 1.45800746442687e-13 -158.052473025951 29.4481572767916 -5.36714306231019 1.18769400029178e-07 MRPL22 other 1.17652691753313e-21 0.00156763731098512 1.80909566186086e-09 7.58477552535774 -5.36714306231019 1.98160611613747e-10 103.510562508256 19.9381126029765 5.19159283375717 2.95554057752309e-07 -112.46311006151 46.5272784606251 -2.41714352918116 0.0159725286471925 GEMIN5 essential 1.68813025033751e-06 1 0.00294046732057772 5.19159283375717 -2.41714352918116 0.000572670180513215 6.303173617864 2.02986939729787 3.10521141224884 0.00201200483122079 43.6480442344265 16.2314377232258 2.68910524001024 0.00740959590280419 OPRK1 other 1 1 1 3.10521141224884 2.68910524001024 1.04013694680482e-33 1496.01451074508 128.131047893837 11.6756596885448 3.53810297860778e-28 -1237.78137056117 416.634876008776 -2.97090196197377 0.00310447833444767 NFE2L1 other 1.46992153322457e-29 1 5.15890795310801e-24 11.6756596885448 -2.97090196197377 0.341999190129794 10.7372673772109 8.61894425233099 1.2457752437959 0.213386155053445 -15.032284428745 28.8898753643993 -0.520330539302678 0.603046077903376 SEMA5B other 1 1 1 1.2457752437959 -0.520330539302678 8.62196548941093e-21 393.686007689665 46.1850420257784 8.5241019694196 1.52384131931517e-16 -560.062493623072 147.628212554311 -3.79373619671125 0.000165043012988253 GSK3B other 1.03799842527018e-16 1 2.00202272531627e-12 8.5241019694196 -3.79373619671125 3.38676999442578e-06 -488.230883858835 229.236140438778 -2.12981636719375 0.0336333428226321 -3603.5931222785 726.932156679406 -4.95726195239395 9.55606788442383e-07 ITGB5 other 0.0215229233145759 0.0121505403150449 1 -2.12981636719375 -4.95726195239395 1.29473105460966e-28 445.862046004865 38.7718073812237 11.4996456476977 1.86381703712734e-27 -126.171035965434 154.760759188197 -0.815265036352039 0.415289606219847 ERC1 other 1.74827534303943e-24 1 2.70719424642747e-23 11.4996456476977 -0.815265036352039 2.000642141703e-12 744.354439962785 101.72525986308 7.31730192643077 9.19280494599566e-13 -172.505386430475 366.723698259724 -0.470396069981552 0.638261649994404 XPO1 essential 1.86779950349392e-08 1 1.11747736923523e-08 7.31730192643077 -0.470396069981552 7.01720006117835e-15 231.391827328168 29.9294108023559 7.73125234092328 5.18285126728248e-14 -316.087412570102 118.383607489505 -2.67002686666839 0.00781129539280433 RNF13 other 7.21368166289134e-11 1 6.49774063379205e-10 7.73125234092328 -2.67002686666839 3.90536304535849e-18 78.799076420847 9.03810099478461 8.71854347127982 3.47875442594272e-17 -45.6301077601729 49.5387837418067 -0.921098668832776 0.357410227345318 PALB2 other 4.42165203995488e-14 1 4.6215252548649e-13 8.71854347127982 -0.921098668832776 1.56164045250414e-17 60.3341303600259 24.3196546105355 2.48087940911334 0.0134144678039639 -325.685809406599 53.3402118379067 -6.10582144660978 1.9764151870783e-09 DOPEY1 other 1.74091677645161e-13 2.75077465737558e-05 1 2.48087940911334 -6.10582144660978 2.18277463079906e-54 238.86495932573 23.8854390833836 10.000442465883 1.03163098730901e-21 -377.832895462648 54.6594382300754 -6.91249137746811 1.35049470242852e-11 LYRM2 other 3.32545715002237e-50 1.95767712064038e-07 1.44026002138211e-17 10.000442465883 -6.91249137746811 3.66511040892989e-12 29.1591293699139 17.8121753585556 1.63703358983091 0.102211490606043 -208.397800171801 39.0711250273458 -5.3338059763046 1.42171023078304e-07 BCKDHB other 3.38582899576943e-08 0.00187025980859509 1 1.63703358983091 -5.3338059763046 1.08374543149823e-29 468.097195415655 46.136999700749 10.1458091868088 9.7078114083679e-22 -739.9716225135 203.33453013259 -3.63918328102452 0.000308266777819809 KAT6A other 1.47898739036564e-25 1 1.35550170695041e-17 10.1458091868088 -3.63918328102452 1.13120213482161e-12 151.770874730546 34.2960570375811 4.42531555636957 1.16592608941867e-05 -329.231662101491 75.1787288985916 -4.37931934903543 1.4307407258109e-05 ZCCHC6 other 1.06672361313678e-08 0.171073668585209 0.104490296133701 4.42531555636957 -4.37931934903543 4.48204431058637e-35 198.203791508876 29.4722418051807 6.72510061565914 4.55440983534266e-11 -568.508180197144 73.099854386319 -7.77714517997102 3.89450411890276e-14 ULK2 other 6.3985664577931e-31 5.80125333551755e-10 5.29450143358585e-07 6.72510061565914 -7.77714517997102 1.70807040074371e-29 249.980374227252 20.6614105010763 12.0989016802231 6.06659979062008e-30 -499.965360116968 284.658340905193 -1.75636996452349 0.0795995119474179 GRHL2 other 2.32485462245226e-25 1 8.91547505229527e-26 12.0989016802231 -1.75636996452349 1.16774021272309e-05 98.0453019304111 75.7200258262237 1.29483978459574 0.195924793082443 -677.174256028793 179.402763122576 -3.77460326832379 0.000177885553311581 TNPO1 other 0.0705782184569835 1 1 1.29483978459574 -3.77460326832379 4.07445130359657e-06 1924.86383631974 396.814914665377 4.85078500122134 1.609509314227e-06 880.924446905079 631.779539038901 1.39435418919263 0.163781952486466 PLOD1 other 0.0256608943100512 1 0.0152951670130992 4.85078500122134 1.39435418919263 0.0805244814156568 11.1725997788938 5.1465428314478 2.17089416037189 0.0303676991757048 3.22172935346465 9.51051990467475 0.338754283231251 0.734924602317982 P2RX5 other 1 1 1 2.17089416037189 0.338754283231251 7.30929235727983e-13 66.8748605399992 10.4877296705452 6.37648591647221 3.8523135321629e-10 -24.0822889465373 19.3228445015883 -1.2463117914424 0.213182452550598 ITGAE other 6.93724937629428e-09 1 4.35735183622946e-06 6.37648591647221 -1.2463117914424 5.3915337899892e-26 267.330973130776 32.8564226740775 8.13633838907517 3.16621178274559e-15 -209.351650004011 61.4586815323647 -3.40638042965118 0.000710586037804286 DIS3 essential 7.06776164529684e-22 1 4.06414944433223e-11 8.13633838907517 -3.40638042965118 1.31820115199378e-26 60.8664060321009 12.9290568715462 4.70772204321056 3.23713238635911e-06 -175.320798815392 24.2309200862817 -7.23541649227962 1.72649157901609e-12 PIBF1 other 1.74068462120779e-22 2.53034605820598e-08 0.0301635995760942 4.70772204321056 -7.23541649227962 1.70235395394109e-12 65.1056241958821 23.9768426014996 2.71535436412342 0.00684907442566184 -190.425614383765 40.8754249710504 -4.65868219152784 4.08347739687374e-06 TDRD3 other 1.59459494865662e-08 0.050386027600025 1 2.71535436412342 -4.65868219152784 2.37745665466073e-39 59.8484413010051 4.97611126346214 12.0271509482618 1.05294903245867e-29 -7.65489244335317 9.51515247626635 -0.804494984441581 0.421463246633508 NUFIP1 other 3.47132446147012e-35 1 1.54604506435907e-25 12.0271509482618 -0.804494984441581 5.82917631424055e-16 102.539934964939 37.618449430418 2.72578845001586 0.00662621688560109 -433.625475988413 74.5669496960852 -5.81525029192898 1.04528175683647e-08 PDS5B other 6.20790404928965e-12 0.000142806393618998 1 2.72578845001586 -5.81525029192898 0.000129128085914973 211.035139191929 49.5120019696282 4.26230269019182 2.39153032740495e-05 212.378752147067 237.689892400667 0.893511920099092 0.37198484059515 OXCT1 other 0.692513924761999 1 0.208982295703108 4.26230269019182 0.893511920099092 0.131469392812562 2.33869561969282 12.3511547274197 0.189350362075935 0.84989057942757 -62.4826119979078 33.1255781024687 -1.88623461316291 0.0598087906745985 EPYC other 1 1 1 0.189350362075935 -1.88623461316291 7.96700640855216e-14 88.7921759673154 34.314890412846 2.58756985375875 0.00993939188846104 -427.187390938993 88.6851772241999 -4.81689730245501 1.92241143853554e-06 CYLD other 7.86741882844526e-10 0.0240935825591659 1 2.58756985375875 -4.81689730245501 3.6794427977165e-10 66.2197262849278 11.9939253028893 5.52110544401805 5.40126907937398e-08 -106.651106264912 43.9726808098746 -2.42539468371377 0.0156419751148854 SLC27A5 other 3.08447689732574e-06 1 0.000560057590840288 5.52110544401805 -2.42539468371377 1.33470370093284e-23 57.0005695054803 6.53841576725332 8.71779518686454 4.12049374154235e-17 -99.3055845744662 23.9714407314528 -4.14266233252171 4.02567081154326e-05 ZNF324 other 1.68853365205013e-19 0.466977814139018 5.46871929377501e-13 8.71779518686454 -4.14266233252171 9.39147149373785e-20 51.1718626492322 5.65725169488873 9.04535725279211 2.69193896816965e-18 -61.1989714923648 28.5715466295244 -2.14195515160263 0.0326445834702317 ZNF671 other 1.10716057439675e-15 1 3.63142566806086e-14 9.04535725279211 -2.14195515160263 7.43219046213329e-38 43.2490916723259 3.06082262333481 14.1298915339319 7.71585075289741e-39 17.9961705425785 15.3638781463111 1.17132994490063 0.241978962926184 ZNF416 other 1.07781626081857e-33 1 1.16378176905952e-34 14.1298915339319 1.17132994490063 3.19826484828227e-37 73.1735187395779 5.40278932664067 13.5436557518106 4.15246205514187e-36 -40.7863213221395 26.9188343437227 -1.51515926734958 0.13032709306793 ZNF586 other 4.62149270576788e-33 1 6.22204914342458e-32 13.5436557518106 -1.51515926734958 9.24402350048997e-18 79.6797774554204 13.4447724808234 5.92645041551055 5.74384105657259e-09 -267.677369237126 49.2918434899886 -5.43045969241325 8.75644434044908e-08 ZNF446 other 1.03736431722498e-13 0.00116145477731717 6.207369029838e-05 5.92645041551055 -5.43045969241325 1.23868653684143e-24 163.99987166962 18.7654365320325 8.73946478088446 2.88359599081436e-17 -408.10941874585 82.186923425289 -4.9656247215147 9.1703637473233e-07 ZNF264 other 1.59220767445597e-20 0.0116702049048436 3.8351826677831e-13 8.73946478088446 -4.9656247215147 2.60511178101356e-10 2732.09779774261 412.79242853208 6.61857536355051 9.32967782324050e-11 147.031342055169 1521.24418288688 0.0966520324016267 0.923041307401338 RPS5 essential 2.20288252202507e-06 1 1.07580514979786e-06 6.61857536355051 0.0966520324016267 3.97577482756172e-06 680.230821475069 296.182715232725 2.29665941491751 0.0220236806264468 3170.68586465386 628.68167087232 5.04338842940086 6.27292098032887e-07 FAT1 other 0.0250791876122593 0.00803686635999735 1 2.29665941491751 5.04338842940086 7.81901883553738e-19 108.954477034137 35.264458167449 3.08963990079701 0.00210817074974381 -662.242378651424 92.560494327334 -7.15469794607457 2.77544599852286e-12 YTHDC1 essential 9.00203638535419e-15 4.06019995123909e-08 1 3.08963990079701 -7.15469794607457 5.45011075075394e-12 173.339743022183 34.4630711765547 5.02972419765382 6.89966112649299e-07 -214.042262826442 71.4509085092485 -2.99565488098359 0.00287698159331612 CHMP2B other 5.0037466802672e-08 1 0.00670578064883853 5.02972419765382 -2.99565488098359 0.000353063730884955 56.9192742498243 39.7639532016392 1.43142896183365 0.152884732297768 -269.324616189814 86.41127311808 -3.11677639353588 0.00192550624235183 SMAP2 other 1 1 1 1.43142896183365 -3.11677639353588 1.02161309771615e-19 197.637999642541 26.4782303938922 7.46416949707224 3.36263218557697e-13 -213.408402967957 58.3580369567328 -3.65688111007195 0.000280201087548815 PPIE essential 1.20315374518031e-15 1 4.13435627216688e-09 7.46416949707224 -3.65688111007195 4.41793634092501e-08 333.056343335658 72.2869281730428 4.60742144884586 5.08964424637179e-06 -326.322541711606 157.087135213969 -2.07733460328957 0.0382418790530008 ZMPSTE24 other 0.000327766697133226 1 0.0468349063551132 4.60742144884586 -2.07733460328957 1.07297892078767e-12 647.691273596212 89.8886898219324 7.2054813000309 2.06854023501298e-12 -404.804362708793 336.401162085428 -1.20333818170935 0.229398338956577 STARD7 other 1.01278480333148e-08 1 2.49858974987218e-08 7.2054813000309 -1.20333818170935 3.27543684938042e-19 82.4253919184809 17.6974409747408 4.65747517034383 4.04363322270154e-06 -263.798944330631 42.4610157092224 -6.21273278381173 1.04737099834101e-09 NOA1 other 3.80900551214449e-15 1.46652887187709e-05 0.0374319127425481 4.65747517034383 -6.21273278381173 6.78104457119334e-08 94.3515298250254 42.6259754234722 2.21347497359721 0.02728603452352 -436.549993982835 102.271408316054 -4.26854387918221 2.32774740395876e-05 REST other 0.000496508083502777 0.274371586504619 1 2.21347497359721 -4.26854387918221 0.238404077832664 0.510216644082331 3.72500593848778 0.136970692800952 0.891104730222235 -16.3136488804517 10.2122904975343 -1.59745248966338 0.110746617360986 HAL other 1 1 1 0.136970692800952 -1.59745248966338 0.000230527221530543 114.176007910038 32.4828623222534 3.51496142111278 0.000476340005857069 -74.0832010224558 74.9854575550797 -0.987967579820912 0.323606133150514 SSH1 other 1 1 1 3.51496142111278 -0.987967579820912 0.717227624923413 -163.878264940106 237.033542625583 -0.691371622449936 0.489650994614021 -576.443530339477 978.521776415449 -0.58909627177754 0.556061162545998 GSTP1 other 1 1 1 -0.691371622449936 -0.58909627177754 7.60892684283629e-12 2332.56805193955 660.801494392 3.52990734999129 0.000451059801202099 -4068.4882759411 1261.05406325386 -3.22625999510545 0.00132988640499261 APLP2 other 6.9393412806667e-08 1 1 3.52990734999129 -3.22625999510545 0.00223394354060503 -123.400408576777 203.850510271653 -0.605347557935136 0.545202875096337 -2266.40474047434 652.810044391494 -3.47176756844624 0.000558529870480165 FAM234B other 1 1 1 -0.605347557935136 -3.47176756844624 0.00932902091082878 20.9129920011732 6.85091492373594 3.05258381310754 0.00238285209553674 14.5037631117385 24.1130354407136 0.601490556732217 0.54777096807438 SLCO1A2 other 1 1 1 3.05258381310754 0.601490556732217 1.25786763479882e-08 679.734012328027 146.644397219775 4.63525388773849 4.47702942872095e-06 -1090.73053414199 466.868766869897 -2.33626794410503 0.0198428646553106 WBP11 essential 9.66545490579413e-05 1 0.0413229816270944 4.63525388773849 -2.33626794410503 4.91016349020049e-24 770.081079599466 131.309322591224 5.86463370919053 7.87187619384991e-09 -1439.65414215471 242.94786922886 -5.92577389842647 5.55975903361412e-09 EIF3I essential 6.25211117207228e-20 7.65356428567319e-05 8.45833097029173e-05 5.86463370919053 -5.92577389842647 0.0257887662187816 321.255067815255 180.104916587598 1.78371070541545 0.0750332001476747 -328.956947441158 309.084750994722 -1.06429368120712 0.287672231654296 NKAIN1 other 1 1 1 1.78371070541545 -1.06429368120712 6.13637677580811e-05 -517.648499238705 182.659282069613 -2.83395671642586 0.00477184730200405 -1458.59098489508 339.287092743121 -4.29898754209138 2.04049900918108e-05 COL16A1 other 0.342760758419221 0.241799132587958 1 -2.83395671642586 -4.29898754209138 1.1844212603664e-24 335.610709589049 63.9205965786353 5.25043143450922 2.18982395468915e-07 -789.587556679958 118.265576519354 -6.67639375647689 6.1221524514973e-11 TXLNA other 1.52304729870516e-20 8.78222769167287e-07 0.00219464156738946 5.25043143450922 -6.67639375647689 0.492203998173772 5.24501876743785 5.56123439575045 0.94313930940328 0.346035349730647 -7.6118037921473 16.0793141402798 -0.473391074130407 0.636127294672725 APOB other 1 1 1 0.94313930940328 -0.473391074130407 2.93202865643701e-06 46.7330535152143 54.2266756915924 0.861809301772485 0.389173584456057 -727.150996852046 156.885710180026 -4.6349090431349 4.47870441933832e-06 NCOA1 other 0.0187503232579147 0.0551552449241514 1 0.861809301772485 -4.6349090431349 3.30648411599609e-17 255.195597551694 28.794107001143 8.86277173108943 1.14187254090886e-17 37.4923618620922 87.8844710606921 0.426609632049789 0.669834331172094 AGBL5 other 3.65498754182207e-13 1 1.52748289797379e-13 8.86277173108943 0.426609632049789 0.0271564814927091 57.2294396761558 21.3111630815604 2.68542075611415 0.00746706026092156 29.2032466392255 62.2768159617473 0.46892645663136 0.639311808498648 EFR3B other 1 1 1 2.68542075611415 0.46892645663136 1.74004502806149e-12 229.56904809067 30.8336281697362 7.44541144580569 3.82575476792322e-13 58.3177090662712 94.3301788159494 0.618229603699328 0.536683696678439 KIF3C other 1.6297261732824e-08 1 4.69573140214896e-09 7.44541144580569 0.618229603699328 3.04779934379805e-14 549.309693505686 85.5084595779088 6.4240391677878 2.90289415859529e-10 -859.719467793334 261.65903506618 -3.28564793329568 0.00108314818635969 RAB10 other 3.05694274182944e-10 1 3.29710718533253e-06 6.4240391677878 -3.28564793329568 2.97147762987051e-12 447.123043879574 84.9497026742313 5.26338562471749 2.04124096716388e-07 -989.810385381431 255.244699103712 -3.87788811621607 0.000118303843527981 HADHA other 2.75693694499386e-08 1 0.00204879355874239 5.26338562471749 -3.87788811621607 2.82344107450394e-05 82.2362538812328 18.5175215402809 4.44099679875331 1.08537748414854e-05 -11.4484614017926 55.7972282772938 -0.205179750952816 0.837508580848642 MAPRE3 other 0.164239567303894 1 0.097510313175905 4.44099679875331 -0.205179750952816 3.02699675566531e-19 520.243388058094 54.7825410127331 9.49651802272504 6.96932015742826e-20 135.25344781797 167.075781596272 0.809533533380684 0.418564882133138 CAD other 3.52401381957458e-15 1 9.57236123622771e-16 9.49651802272504 0.809533533380684 9.3073681783983e-07 1363.28729341798 289.698914889602 4.70587642324272 3.21593328784306e-06 -1973.27455835215 1263.68141203213 -1.56152851467437 0.118984933458818 CD59 other 0.00623500594270902 1 0.0299724982426974 4.70587642324272 -1.56152851467437 0.0672710090096714 -25.8875318546427 94.9843392334465 -0.272545264446363 0.785307754595206 -558.506187176459 247.158986674049 -2.25970414708413 0.0242402700273551 CD82 other 1 1 1 -0.272545264446363 -2.25970414708413 1.14443145602953e-40 85.1353241609057 11.2280737110164 7.58236242049026 1.51367679449156e-13 -204.583143306607 24.1791215560247 -8.46114871595203 2.55496223749484e-16 AK6 essential 1.68071203632497e-36 3.87051229358093e-12 1.87771606356678e-09 7.58236242049026 -8.46114871595203 0.253262314229469 2.24989828562192 6.08977001135863 0.369455378680215 0.711932624399985 23.7725280436357 14.4768451054865 1.64210695565336 0.101147877791167 FCN1 other 1 1 1 0.369455378680215 1.64210695565336 0.143464449106001 61.1047581732358 33.0865733756042 1.84681434005161 0.065326083497322 -104.648572412739 143.07618615913 -0.731418520593974 0.46484378894116 MYNN other 1 1 1 1.84681434005161 -0.731418520593974 0.580659568205779 -12.4426400492326 11.940292949863 -1.04207158915438 0.297849150967442 -1.67858575769091 50.923577759105 -0.032962840231523 0.973716514488781 MECOM og 1 1 1 -1.04207158915438 -0.032962840231523 3.7040184771186e-25 128.699333061159 57.9517848178838 2.22080016112709 0.0267763427234956 -1160.50213777068 128.28547638423 -9.04624724855714 2.62154505619084e-18 SCAMP1 other 4.79411111493461e-21 4.01358548102818e-14 1 2.22080016112709 -9.04624724855714 8.13406788306018e-28 216.661991098973 25.7800243540355 8.40425858888135 4.00041327917189e-16 -247.00875893297 69.3034859631613 -3.5641606695552 0.000398059911039394 PREP other 1.08931437089942e-23 1 5.21733899869598e-12 8.40425858888135 -3.5641606695552 5.34250968242998e-22 63.4003095606619 9.77331381603281 6.48708419212486 2.02804657494786e-10 -74.501873672436 21.8152305231511 -3.41513116688692 0.000686946846158786 HACE1 other 6.58357468165846e-18 1 2.31318828545118e-06 6.48708419212486 -3.41513116688692 7.80400936054824e-30 349.199013354009 34.1083661368631 10.237928488067 1.43960879372126e-22 -169.261512490614 82.0734520565062 -2.06231745161737 0.0396643053784741 SEH1L essential 1.06649591921252e-25 1 2.0245218466102e-18 10.237928488067 -2.06231745161737 4.52297003701278e-14 95.1738263532409 15.4430553059723 6.16288839660079 1.39996372428992e-09 -86.3093529174062 36.593559726017 -2.35859406856346 0.018700293193003 WDR47 other 4.50533045386843e-10 1 1.54877986818194e-05 6.16288839660079 -2.35859406856346 1.31808162594757e-07 117.301501295131 41.889611078906 2.80025281385816 0.00528743314374898 -361.940254797275 89.9122697902037 -4.02548234675652 6.49118971544388e-05 WDFY1 other 0.000945591758454784 0.742137720166699 1 2.80025281385816 -4.02548234675652 0.0223176140416551 7.60470015448065 6.57956729317323 1.15580551358918 0.248266223711896 -26.6865472018154 14.8236139574941 -1.80027267833186 0.0723694085451507 OVGP1 other 1 1 1 1.15580551358918 -1.80027267833186 6.77987075112398e-07 204.309928474704 72.297807871321 2.8259491468724 0.0048919513200349 -461.852774209232 153.482180826313 -3.0091621823636 0.00274430621564202 SLC25A24 other 0.00459675236926206 1 1 2.8259491468724 -3.0091621823636 7.81135659269194e-17 55.8073043388387 19.3270249528331 2.88752689433755 0.00403643058823924 -253.736459006833 41.2736652190605 -6.14765995847771 1.51723839356354e-09 MAP3K4 other 8.53937502713082e-13 2.11685100669985e-05 1 2.88752689433755 -6.14765995847771 0.35672359953911 12.3897643252754 8.69896832354766 1.42427973806238 0.154944189869404 6.22781090990964 27.8290976924943 0.223787741116354 0.823007264339479 PILRA other 1 1 1 1.42427973806238 0.223787741116354 8.19792640712394e-11 242.120502296072 34.9033660255392 6.93688116266235 1.14653871953931e-11 177.894454733947 343.391305580029 0.518051714889699 0.604633584851903 IGSF9 other 7.10186364649147e-07 1 1.35818976716626e-07 6.93688116266235 0.518051714889699 0.0109274933872217 -22.359783224358 7.61685259769172 -2.93556727500991 0.0034701220698953 -35.4676991985857 24.8034464973235 -1.42995043863816 0.153305303946332 ABCB1 other 1 1 1 -2.93556727500991 -1.42995043863816 1.19694051702061e-26 169.158630361945 17.6114825244353 9.60501934617053 2.77741824623604e-20 -251.295840687624 82.7507417838244 -3.0367805202774 0.00250580281333372 ZNF213 other 1.58091903488083e-22 1 3.83033750338412e-16 9.60501934617053 -3.0367805202774 0.166771999589646 50.9906818380207 35.7662413261508 1.42566509499947 0.154536472597228 189.581119977269 115.052977670007 1.64777238987262 0.0999746944252652 AKR1B1 other 1 1 1 1.42566509499947 1.64777238987262 4.98313102035169e-41 1087.89939747247 73.7231979320998 14.7565410615319 1.98792866585217e-41 -1784.2348232514 795.546379047641 -2.24277913927197 0.0253307202567472 CPNE3 other 7.3296874178353e-37 1 3.01230830736579e-37 14.7565410615319 -2.24277913927197 4.44477402135041e-27 287.661770020062 29.557612782129 9.73223961422172 9.55674649434026e-21 -540.092570751335 152.070373332632 -3.5515962703002 0.000416057162935684 RRN3 essential 5.90532676476615e-23 1 1.32313155214141e-16 9.73223961422172 -3.5515962703002 8.2616561371985e-104 2381.38867777402 86.0590758578273 27.6715576368512 2.89110253299092e-102 -643.345048552265 714.477588517796 -0.900441187927115 0.368326934643222 CTTN other 1.29104900456001e-99 1 4.5182150385582e-98 27.6715576368512 -0.900441187927115 0.0805733981685438 5.70608340281998 18.7826196141398 0.303795930495466 0.761408247571797 -169.976529027184 82.0363090509909 -2.07196704719531 0.0387745226517672 WNT11 other 1 1 1 0.303795930495466 -2.07196704719531 1.56580997146199e-24 218.343459045974 20.1981251426762 10.8100854660337 8.39392334663932e-25 -39.2602117231736 70.8744026880717 -0.553940636310734 0.579847511403958 MTIF2 other 2.01003026036575e-20 1 1.20058285626982e-20 10.8100854660337 -0.553940636310734 1.29274456409223e-101 572.623344673723 20.7964465365318 27.5346725060857 2.12829154819e-98 -66.9633377500761 131.617599705055 -0.508771911204396 0.611162570491584 DDHD2 other 2.01965483248129e-97 1 3.32502988573724e-94 27.5346725060857 -0.508771911204396 0.00123822311150266 -384.706947058312 237.850319681192 -1.61743296193153 0.106368810483622 -1764.85184882887 481.681991666012 -3.66393570730081 0.000272866962563992 TTC39A other 1 1 1 -1.61743296193153 -3.66393570730081 2.256687735191e-07 65.0819154926863 51.9801562959672 1.25205309353284 0.211092543214708 -493.699963427741 105.267486061453 -4.68995681287124 3.46589902902568e-06 EPS15 other 0.00159006217821558 0.0428905004841928 1 1.25205309353284 -4.68995681287124 1.64066624323031e-14 107.923194968502 13.7693314942035 7.83794006367957 2.45387220055842e-14 10.2387257592852 28.6767742276262 0.35703896393694 0.721202118078474 ORC1 other 1.66248710426528e-10 1 3.09727749154483e-10 7.83794006367957 0.35703896393694 2.99408231945522e-14 61.844513146559 26.5390581350822 2.33032057248506 0.0201559908357565 -375.376445577314 58.7896376474317 -6.3850784015457 3.69062339133472e-10 MGST2 other 3.00426219934137e-10 5.21927960002556e-06 1 2.33032057248506 -6.3850784015457 1.79004349644415e-39 420.914911290856 32.000073319721 13.1535608398577 1.62769143308713e-34 -298.15451888617 118.769554989918 -2.51036150561884 0.0123492941598646 CHERP essential 2.61507454395525e-35 1 2.42900392559592e-30 13.1535608398577 -2.51036150561884 3.21935321578644e-15 164.155408392234 47.0564344806103 3.48847952897653 0.00052481118756879 -576.349802593894 92.2994560908255 -6.24434668419658 8.53878456353701e-10 ATG16L1 other 3.34844927973948e-11 1.19799147426424e-05 1 3.48847952897653 -6.24434668419658 7.98733941127906e-27 57.7626786197665 29.6105921865661 1.95074378302953 0.0515977747640125 -594.189277945743 58.2912261614445 -10.1934599265431 1.85903558145717e-22 USP40 other 1.05768348484157e-22 2.88280647616564e-18 1 1.95074378302953 -10.1934599265431 1.14308858429685e-09 83.7220950734582 68.6652156438571 1.21927957683401 0.223267470034924 -772.598812237712 139.963362178873 -5.52000752347125 5.25845216089753e-08 POMGNT1 other 9.32188740494082e-06 0.000702371455131084 1 1.21927957683401 -5.52000752347125 8.86336569703586e-18 165.568018286222 18.9314196793836 8.74567365206772 2.77125190773365e-17 23.2336079406253 38.5873028021223 0.602104999661896 0.547355111959876 RAD54L other 9.95090066806216e-14 1 3.68687353804884e-13 8.74567365206772 0.602104999661896 1.99629647276593e-13 345.896265672256 69.525456094656 4.97510243156598 8.7698704188326e-07 -545.453467167129 142.738810206953 -3.82133959486065 0.000148106427194195 MAST2 other 1.94159794941214e-09 1 0.00846906386346664 4.97510243156598 -3.82133959486065 2.93482335328291e-31 1555.65758665927 139.534359961374 11.1489212197619 3.9801251486265e-26 -517.103479401136 339.567609303651 -1.52282922526549 0.128385723305773 DNAJA1 other 4.06502382663216e-27 1 5.7373504017451e-22 11.1489212197619 -1.52282922526549 1.15781163014535e-05 400.641762988768 315.215580093585 1.27100875810079 0.204271759614485 -3099.05360090501 797.988193380598 -3.88358327430407 0.000115663583389031 B4GALT1 other 0.0700325945637015 1 1 1.27100875810079 -3.88358327430407 2.69142874322059e-26 299.987495092549 44.4106672587944 6.75485223728864 3.70178251381781e-11 -701.060525690799 112.670789803342 -6.22220299435593 9.82721884980471e-10 CHMP5 other 3.5394979402094e-22 1.37698990523464e-05 4.31701876761433e-07 6.75485223728864 -6.22220299435593 1.16589266595582e-30 200.717721101787 28.7583306578625 6.97946356795613 8.70436142772875e-12 -525.474619884742 72.9604851412219 -7.20218100068326 1.99628955703279e-12 NFX1 other 1.60473466542159e-26 2.92456420105303e-08 1.03460039929984e-07 6.97946356795613 -7.20218100068326 3.84149025140564e-07 45.199141048537 13.7461022578066 3.28814235488957 0.0010741533044203 -84.0062253719198 31.4444558379902 -2.6715751038829 0.00777751144897065 DIMT1 essential 0.00265869540299784 1 1 3.28814235488957 -2.6715751038829 7.64837281999621e-24 858.693703585562 107.897292313049 7.95843607543161 1.02241571931432e-14 -1880.88980329928 378.422939139967 -4.97033770620231 8.97376337914824e-07 EIF2AK1 other 9.71113896954919e-20 0.0114262929106694 1.30133072754327e-10 7.95843607543161 -4.97033770620231 0.111968888027512 34.0910820154736 17.2104323573554 1.98083820950051 0.0481116949778847 77.0425073953296 65.3096077662845 1.17965043781969 0.238653944915855 EPDR1 other 1 1 1 1.98083820950051 1.17965043781969 1.03553711955518e-22 259.702171275996 24.6107360680928 10.5523934984088 8.60677361236763e-24 184.770020081492 125.933082753191 1.46720794919007 0.142902724365584 SNX10 other 1.29214321778096e-18 1 1.22345286899806e-19 10.5523934984088 1.46720794919007 1.21217122700574e-57 496.999291245156 27.0780772538667 18.3543050928472 6.73997088303789e-59 317.76695995719 149.104537929883 2.13116893938279 0.0335237258821716 SEPHS1 other 1.85692510265009e-53 1 1.04085370346754e-54 18.3543050928472 2.13116893938279 3.19016982785415e-14 282.874181961175 38.3642273108375 7.37338405565296 6.48973183751923e-13 -105.874335725502 168.738195260327 -0.627447363426879 0.530637785418269 MRPL28 essential 3.19846426940657e-10 1 7.91877078814096e-09 7.37338405565296 -0.627447363426879 2.51485640106771e-16 180.823469921009 27.1826176358757 6.65217280922782 7.01825232060184e-11 -365.43356773554 103.612937673042 -3.52691059574716 0.000455744758546309 ITPKC other 2.70925480087024e-12 1 8.11731063400809e-07 6.65217280922782 -3.52691059574716 0.272275654352408 928.279622490504 999.004319200953 0.929204813882069 0.353202003917016 -3048.04579830897 3244.4757559335 -0.939457104197712 0.347920054166895 CEACAM6 other 1 1 1 0.929204813882069 -0.939457104197712 0.375419664332077 1.29420761765686 36.4731802672535 0.0354838160032574 0.971706896043534 113.50689118069 85.5718860239399 1.32645073580515 0.185243971292971 FAT2 other 1 1 1 0.0354838160032574 1.32645073580515 2.10447865821993e-33 123.857840735308 20.5203475144731 6.0358549312067 2.92149607289161e-09 -433.019470360868 48.3860229402725 -8.94926766135305 5.57570589577028e-18 RBM22 essential 2.96773580382175e-29 8.52469674404318e-14 3.19085801081222e-05 6.0358549312067 -8.94926766135305 9.61623994474005e-18 1826.45944754218 250.029765107464 7.3049680575317 9.88409513491441e-13 -1810.32900849929 567.995937935521 -3.1872217521119 0.00151865678263901 TMED2 essential 1.0784613098026e-13 1 1.20081871794075e-08 7.3049680575317 -3.1872217521119 0.342821223839716 8.82346197554678 19.3468342238582 0.456067482330821 0.648523796031378 -163.43452724272 119.663587394025 -1.36578328296783 0.172572430135833 ERO1B other 1 1 1 0.456067482330821 -1.36578328296783 4.8965392839987e-17 194.355928905229 48.415410169565 4.0143402322636 6.79624684525502e-05 -723.294090329399 108.492138834813 -6.66678800968854 6.42157437999032e-11 ZFAND6 other 5.38619321239857e-13 9.20725334603012e-07 0.570273072785349 4.0143402322636 -6.66678800968854 1.24622658537574e-07 55.7954953150388 13.4811164617663 4.13878891064251 4.0422150739266e-05 -19.5546638178539 28.7843878748308 -0.679349649639506 0.497203703938673 HSD17B2 other 0.000895787669568082 1 0.346296565383292 4.13878891064251 -0.679349649639506 0.0743913214617813 -24.79426539632 10.9072565767019 -2.27318989169843 0.0234110841469688 -11.6838353145387 40.2189952575044 -0.290505400240167 0.771542403501677 LAT2 other 1 1 1 -2.27318989169843 -0.290505400240167 2.09046038417288e-39 174.685067477894 18.3813315835297 9.50339569710049 6.36231136529838e-20 -126.728383527285 33.8880485812509 -3.73961879874665 0.000203765250114289 ZW10 essential 3.05269929900765e-35 1 8.74181581591998e-16 9.50339569710049 -3.73961879874665 1.1886530507367e-48 99.7857392018423 13.6151504609353 7.32902214251309 8.4523046882542e-13 -202.619788854028 25.0839911175143 -8.07765350835872 4.2938925531934e-15 ALG9 other 1.79094355154499e-44 6.44942661489649e-11 1.02830738837301e-08 7.32902214251309 -8.07765350835872 0.900842762432902 33.5642008510662 100.789167712719 0.333013969782297 0.739251802996429 -80.696265147487 355.947321128573 -0.226708449136883 0.82073546349311 MYBPC2 other 1 1 1 0.333013969782297 -0.226708449136883 0.668775354716968 -5.01595125198855 11.3322906114363 -0.44262465762452 0.658217150976728 -22.8902609292251 25.5164049890024 -0.89708017015292 0.370081908422388 NOX4 other 1 1 1 -0.44262465762452 -0.89708017015292 2.85895284721648e-17 119.002528043661 34.0962230611099 3.49019678309752 0.000521816407262013 -449.744348986759 74.9650184057757 -5.99938956264043 3.61605780145406e-09 ACOX3 other 3.16571848772281e-13 5.00173115097126e-05 1 3.49019678309752 -5.99938956264043 1.73802399044075e-16 238.033334529318 34.0272959266403 6.99536439928977 7.92073770384597e-12 -32.6533791833739 66.8371775514798 -0.488551138447212 0.625359329470436 MTMR2 other 1.87932534086358e-12 1 9.42250957249517e-08 6.99536439928977 -0.488551138447212 0.118757762207804 111.127548040836 61.5916894948342 1.80426205145998 0.0717411800794652 -105.929863909766 196.529656765882 -0.53900192801922 0.590105223878042 PPP1R15A other 1 1 1 1.80426205145998 -0.53900192801922 0.13899563051625 -4.58541489547406 16.9406280099435 -0.270675614433102 0.786742822767995 -106.920966251435 54.0549518206009 -1.97800502359686 0.04843043959769 HSD17B14 other 1 1 1 -0.270675614433102 -1.97800502359686 0.0613260983176078 25.9942426974593 12.2495096679458 2.12206393579005 0.0342844787209812 -14.8590283349291 38.6952744944263 -0.384001109413746 0.701127945079643 ACHE other 1 1 1 2.12206393579005 -0.384001109413746 0.414771560383263 1580.12285638617 1249.09401335223 1.26501515458036 0.206405524840626 2799.43236928801 3802.3556625911 0.736236327608646 0.461903072822977 FTL other 1 1 1 1.26501515458036 0.736236327608646 7.79152286728219e-07 107.132402240738 51.0154058186736 2.10000098051799 0.0361895048800738 -661.567130860993 160.645628142149 -4.11817699934914 4.41379590178818e-05 SRRT essential 0.00525616132626857 0.511029289509035 1 2.10000098051799 -4.11817699934914 0.180725913468485 50.0626422504817 30.0536009076535 1.66577850036375 0.0963311242679363 -40.5938220351005 95.9236339365217 -0.423188951139652 0.672324041590787 BAX og 1 1 1 1.66577850036375 -0.423188951139652 3.51574929812431e-13 81.1708260522425 20.1301535452539 4.03230039302805 6.38376234668745e-05 -516.997719813409 96.5488405286407 -5.35477916650946 1.30724620632912e-07 NLK other 3.38355712451483e-09 0.00172125107987356 0.537193601473749 4.03230039302805 -5.35477916650946 3.95606423326094e-52 440.005069744836 30.384517111153 14.4812263474586 4.54883775091853e-40 -472.857855697356 112.148951260811 -4.21633773995521 2.93692282196811e-05 PIGS other 6.00609671893676e-48 0.343854923996026 6.87602314428845e-36 14.4812263474586 -4.21633773995521 0.646160495837457 10.5538652363932 95.0823167550161 0.110997140126336 0.911659856510924 -214.269553227393 254.624750809501 -0.841511096412225 0.400434168113057 ADAMTS2 other 1 1 1 0.110997140126336 -0.841511096412225 0.762680714235593 -15.1700484864268 23.3282264453544 -0.650287261312476 0.515786873546189 -35.0100071007372 63.1975488390023 -0.553977294118262 0.579826718097497 TMPRSS11E other 1 1 1 -0.650287261312476 -0.553977294118262 1.07318586326333e-44 317.784271858929 27.0663986554522 11.7409144786581 1.7166295426464e-28 -319.386938551609 63.4204026460556 -5.03602823738101 6.50009053736245e-07 ATXN7L3 other 1.60065671505726e-40 0.00832336593309262 2.50645079521801e-24 11.7409144786581 -5.03602823738101 1.96422542041453e-23 120.738223012072 12.2177032512804 9.88223568119641 2.81230946328581e-21 -84.4108686698119 36.6834971444577 -2.30105838430306 0.0217690492234358 PGS1 essential 2.47806679039498e-19 1 3.91051630869892e-17 9.88223568119641 -2.30105838430306 1.89286331515029e-85 1085.53851953466 47.0437069387017 23.0751058999055 7.28297158051408e-82 -510.456424711897 209.062417896752 -2.44164603972003 0.014949555465351 PSMC5 essential 2.94813461334658e-81 1 1.1348326316757e-77 23.0751058999055 -2.44164603972003 2.25922439213353e-19 66.9614781927621 8.37055745552511 7.99964381685991 7.7025979547064e-15 -55.2044784245419 23.9510631479945 -2.30488634610628 0.0215527203484882 UIMC1 other 2.64148515928252e-15 1 9.82466369122801e-11 7.99964381685991 -2.30488634610628 0.900719355063092 1.84553433351411 4.34538938129464 0.424710922675534 0.67121565292626 1.18296479283411 9.22509497275873 0.128233345708347 0.898011789852696 CETP other 1 1 1 0.424710922675534 0.128233345708347 0.0667006481354057 -1178.71893486925 614.207811292267 -1.91908815420187 0.0554989515076831 -198.148222301621 1390.06464070179 -0.142546048938835 0.886701780219979 MMP2 other 1 1 1 -1.91908815420187 -0.142546048938835 0.290109512268342 24.4803908228947 23.6655013005133 1.03443364719106 0.301393950873564 -16.0515078860633 54.2213666001543 -0.296036579166886 0.767315327282864 LPCAT2 other 1 1 1 1.03443364719106 -0.296036579166886 0.438506460280511 -11.4397520486685 18.8896152706089 -0.605610642926541 0.545025444382062 -52.7410829408543 41.7158393257322 -1.26429394190137 0.206664967635399 GNAO1 other 1 1 1 -0.605610642926541 -1.26429394190137 1.07311014576959e-71 208.640386668342 23.1274166080579 9.02134424281738 3.15004139820493e-18 -457.969801107089 49.6694592516023 -9.22035005026384 6.40108026298841e-19 OGFOD1 other 1.66235492681167e-67 9.81861701539793e-15 4.24531079236079e-14 9.02134424281738 -9.22035005026384 0.00170338710329619 161.670744072755 49.1695712459676 3.28802427956932 0.00107410315561082 37.7886448255441 96.1949251809618 0.392834078871169 0.694595916389382 SH3BP2 other 1 1 1 3.28802427956932 0.392834078871169 1.29575715996793e-21 258.359630908761 33.862741180455 7.62961360782811 1.06582164657035e-13 -141.14890093579 66.1770487959958 -2.13289808934982 0.0333817251695451 NOP14 essential 1.58354482519681e-17 1 1.32652162132146e-09 7.62961360782811 -2.13289808934982 3.78338456128216e-43 418.071030362666 113.103610423492 3.69635442049365 0.000240917273848302 -2442.16329032484 221.155465915713 -11.0427444341602 1.02683651790972e-25 ADD1 other 5.61492102739885e-39 1.60063276411767e-21 1 3.69635442049365 -11.0427444341602 8.41825142765962e-18 78.1629542786965 9.56425322699957 8.1724053539324 2.14697455790776e-15 -41.2338004847427 23.497917462412 -1.7547853145157 0.0798610438907356 L2HGDH other 9.45874730411835e-14 1 2.76465913821782e-11 8.1724053539324 -1.7547853145157 3.93212948751262e-08 64.3423715328832 30.6710787911103 2.09781899003606 0.0363835869299308 -338.381610735741 72.9472341272622 -4.63871748921156 4.4000738044065e-06 TXNDC16 other 0.000293140253294066 0.0542177094178969 1 2.09781899003606 -4.63871748921156 0.000286687705313486 13.1726872269923 52.9228949422087 0.248903376154626 0.803529638596298 -477.089893816307 125.858839752798 -3.79067449496094 0.00016706963072216 NID2 other 1 1 1 0.248903376154626 -3.79067449496094 8.42262380786024e-05 72.5642411294046 20.3599655411209 3.56406502667438 0.000397205048555046 -134.345540813618 68.8677995813018 -1.95077440589657 0.0515959941620109 GMCL1 other 0.462317820813448 1 1 3.56406502667438 -1.95077440589657 4.84458147884339e-35 1327.66346225435 114.396410057551 11.6058140424724 6.87216815985967e-28 -1063.00754148711 322.798678148863 -3.29309756651757 0.00105740011740422 SF3B2 essential 6.91418668660528e-31 1 1.00072512743877e-23 11.6058140424724 -3.29309756651757 8.72260795698444e-25 162.278285237743 17.2425681975374 9.41149157008526 1.39954078134094e-19 -425.177180214178 99.1844256654052 -4.28673329871866 2.14765941433374e-05 KLHL42 other 1.12373358309831e-20 0.253982202339109 1.91611128373388e-15 9.41149157008526 -4.28673329871866 4.25022269603604e-35 9505.44774123999 700.025508883349 13.5787162333594 3.09609501011868e-36 5054.60696091455 5420.08944649817 0.93256891990597 0.351468822755002 GNAS other 6.06889298766987e-31 1 4.64166563916993e-32 13.5787162333594 0.93256891990597 6.66537125009969e-40 521.915284650595 37.245771072925 14.0127394229191 5.66221592454092e-38 -353.540486688627 172.318584782819 -2.05166777068307 0.0407120720539547 DNM1L essential 9.76010312152097e-36 1 8.51767141528691e-34 14.0127394229191 -2.05166777068307 0.686076122660755 25.309295368184 55.1895499612921 0.458588544134443 0.646714515633632 253.378053148279 314.995186686576 0.804387063223265 0.421528109657601 PTHLH other 1 1 1 0.458588544134443 0.804387063223265 2.33070905912566e-27 6.46721580779581 0.550301841245699 11.7521246033926 1.96741872131436e-28 9.42154646191033 4.25173617841685 2.21592922668558 0.0271302443296859 PHACTR3 other 3.10543675037902e-23 1 2.87243133311896e-24 11.7521246033926 2.21592922668558 5.78048989893045e-64 488.187089943111 25.5014573392987 19.143497700847 1.23425970533489e-62 -121.081740231412 125.17996430364 -0.96726134174086 0.333849632086624 ERGIC2 other 8.91640566910021e-60 1 1.9095231901236e-58 19.143497700847 -0.96726134174086 1.77647433361979e-18 325.317415325443 34.6523997258023 9.38801981679816 1.79400715236211e-19 145.829595937875 333.250005025116 0.437598180761869 0.661855856215608 TFAP2C other 2.02855604156044e-14 1 2.45384298300089e-15 9.38801981679816 0.437598180761869 4.41705830748745e-28 178.581416566055 15.4977849515268 11.5230284279084 1.44821664452142e-27 533.502464032729 123.634417520791 4.31516138249295 1.90383542999394e-05 AURKA essential 5.93431783610939e-24 0.225890073768781 2.10440360615408e-23 11.5230284279084 4.31516138249295 0.0672478520499981 -2.1371815022728 1.13111728864875 -1.8894428753944 0.0593811676989614 10.7477641987487 9.34355929039991 1.15028586694917 0.250547840768051 CASS4 other 1 1 1 -1.8894428753944 1.15028586694917 1.78229027451984e-113 230.831104960369 7.80245666150767 29.5844135987505 2.46167660390116e-112 64.8148229692072 47.3889593143102 1.36771990579744 0.172008103485009 AAMDC other 2.78785844740394e-109 1 3.85080071148259e-108 29.5844135987505 1.36771990579744 0.000585518572476383 -4.08052556858615 10.6305998625429 -0.383847160211906 0.701241984747878 -95.266930286276 25.3678472631718 -3.75542036728443 0.000191739041806726 RFX2 other 1 1 1 -0.383847160211906 -3.75542036728443 2.45196883009971e-59 142.086907460499 7.76955101620877 18.2876600158849 7.18013624966736e-58 -40.3532656160186 29.9531828500979 -1.34721127360549 0.178508117167855 METTL2A other 3.76328176043704e-55 1 1.10825403013616e-53 18.2876600158849 -1.34721127360549 1.44600395269581e-06 120.47736089559 23.2593686901046 5.17973477701676 3.13635466881978e-07 38.0263813455998 73.9402190651236 0.514285483954378 0.607261647302769 SULT2B1 other 0.00951181400083304 1 0.00311502745707181 5.17973477701676 0.514285483954378 1.38678202487946e-07 99.7417287331341 20.0333175129729 4.97879238765845 8.61611656285124e-07 -33.6294146142752 39.4607054076527 -0.85222537881326 0.394466117380973 ALG6 other 0.000993490642623649 1 0.00832575343468315 4.97879238765845 -0.85222537881326 1.00037781611915e-29 258.378938245347 21.6076458800174 11.9577551242773 2.48786361852739e-29 -74.0871685038876 87.3854283303866 -0.847820625468345 0.39692203140386 CNOT3 other 1.36551571900264e-25 1 3.64546656022819e-25 11.9577551242773 -0.847820625468345 0.000246849727933944 38.4430077583782 18.038735363139 2.13113652284816 0.0335297420542885 -122.737113917845 43.2663150385174 -2.83678223598611 0.0047285090845686 PTPN4 other 1 1 1 2.13113652284816 -2.83678223598611 4.86429423279673e-11 343.414771980549 56.502142683455 6.07790706105571 2.2946744067051e-09 -255.456323651815 138.070820798866 -1.85018327676889 0.0648301777978971 DDX18 essential 4.26112174792994e-07 1 2.51588101951147e-05 6.07790706105571 -1.85018327676889 5.60708750543598e-28 213.421071657021 52.6866631807422 4.05076083343668 5.84657388249914e-05 -871.865112716229 106.12383075196 -8.21554505277908 1.5446655492048e-15 GNA11 other 7.52078647104128e-24 2.32920118164592e-11 0.493567767160577 4.05076083343668 -8.21554505277908 0.000222982885199801 100.183334630293 58.9580351579611 1.69923123051643 0.0898462801379912 -216.438269588759 93.323512218844 -2.31922550322807 0.0207516080194074 ASAP3 other 1 1 1 1.69923123051643 -2.31922550322807 7.11264525911754e-48 137.462728474895 8.52500990168689 16.1246415030785 5.81356135256511e-48 -55.5255720644484 70.756172892172 -0.784745270904714 0.432950275365592 EDEM2 other 1.06988409987646e-43 1 8.88893530807205e-44 16.1246415030785 -0.784745270904714 1.34675089356561e-14 82.2775963938108 9.99557948131223 8.23139834440187 1.37792177214385e-15 58.0648209742931 57.260881943299 1.01403993448425 0.311014487472187 DNMT3B other 1.36883760822008e-10 1 1.77903480001492e-11 8.23139834440187 1.01403993448425 0.747310507288575 -0.568656618644199 2.37056651268487 -0.239882161332038 0.810516140055205 -10.4427792741671 13.9722350517744 -0.747395047068073 0.455162962917555 REM1 other 1 1 1 -0.239882161332038 -0.747395047068073 6.29404697321343e-11 508.308181585691 74.0049121022456 6.86857354662363 1.83668323763657e-11 959.642881030289 441.612033363661 2.1730451358422 0.0302224941120768 TPX2 essential 5.48463253245819e-07 1 2.16177617069824e-07 6.86857354662363 2.1730451358422 2.15494977602627e-05 49.9926292996336 10.8247832764818 4.61834921057947 4.86253119399698e-06 0.443930259485926 59.8080296631034 0.00742258626452952 0.994080485664099 FER1L4 other 0.126847156156753 1 0.0447693247031302 4.61834921057947 0.00742258626452952 1.02304614053623e-09 153.005946634371 24.7251680365442 6.18826721048872 1.2183692849697e-09 -203.45396795449 145.934411779594 -1.39414662705989 0.163857505126538 PDRG1 essential 8.3685174295864e-06 1 1.35190255860238e-05 6.18826721048872 -1.39414662705989 6.11331032539911e-19 369.172321529628 44.5324010409971 8.28997118726572 9.36883245285924e-16 -1048.24978297703 296.18509932259 -3.5391712323628 0.000436670938823475 EPB41L1 other 7.05476011551058e-15 1 1.21354486761886e-11 8.28997118726572 -3.5391712323628 6.36795237635132e-10 56.6557307223661 8.66160757616878 6.5410179604819 1.42588364834873e-10 68.8274304692785 21.2741739772111 3.23525747899808 0.00129015519182638 SLC15A1 other 5.27011738666835e-06 1 1.63477560283181e-06 6.5410179604819 3.23525747899808 2.63767979493521e-16 288.075137585994 45.8795925712594 6.27893844389661 7.03908919401673e-10 -415.025072893155 112.686984001677 -3.68299033442034 0.000253848678219998 DOCK9 other 2.83972606722725e-12 1 7.88166817054053e-06 6.27893844389661 -3.68299033442034 2.27586140614344e-27 241.565305716369 33.7021758815641 7.16764717403636 2.48861344709302e-12 -695.015271132459 97.145065323353 -7.1544063387992 2.71835650965598e-12 ANKRD10 other 3.03258532368613e-23 3.9769555736267e-08 2.9990280650918e-08 7.16764717403636 -7.1544063387992 4.02452978807595e-58 92.1752875921205 5.35058222723029 17.2271509300465 2.85843236868664e-53 -6.36414742799425 13.3858006477731 -0.475440176905145 0.634666593925753 TGDS other 6.16920171214163e-54 1 4.39569729656631e-49 17.2271509300465 -0.475440176905145 0.000290285549349102 38.3514837917161 10.3959162169816 3.68909127307793 0.00024848181118283 63.0211257335963 19.0181347302795 3.31373852522235 0.000983960887146799 DOCK3 other 1 1 1 3.68909127307793 3.31373852522235 1.28538545937319e-28 25.0580687482097 11.9343637355557 2.09965686512093 0.036236654812677 -202.687471966551 21.7818709343713 -9.30532884788676 3.6298407676601e-19 C3orf18 other 1.73578452433755e-24 5.57180557835825e-15 1 2.09965686512093 -9.30532884788676 2.60363463378713e-69 335.358347262791 26.5042897010035 12.6529837639865 2.35980102516317e-32 -322.098966822598 57.8164388723811 -5.57106202153977 3.98319333651203e-08 COQ9 other 4.02704168807856e-65 0.000534265722226359 3.49816903970189e-28 12.6529837639865 -5.57106202153977 1.97522821482245e-06 53.8620808937604 11.0605853970171 4.86973147988047 1.47138547590169e-06 82.2183890168729 28.1672423228351 2.91893640401633 0.00365930693842553 TMEM40 other 0.0128547852220645 1 0.01400906111606 4.86973147988047 2.91893640401633 1.14252473455312e-39 12.7463752354972 7.56000178970838 1.68602807116384 0.0923856737545115 -164.29478623513 13.9595933583171 -11.7693103243042 1.5490980082124e-28 KIF9 other 1.67071391933702e-35 2.42093036723434e-24 1 1.68602807116384 -11.7693103243042 0.727267659198879 6.77518556790362 10.8591806281708 0.623913147768025 0.532948581462955 -5.32737688216797 24.8396869938089 -0.214470370882523 0.830261384161461 ARHGAP28 other 1 1 1 0.623913147768025 -0.214470370882523 2.2420149360139e-24 163.687254068688 18.0221583064409 9.08255555663318 1.92528448202654e-18 -273.60959085615 73.361292013199 -3.7296179408471 0.000211776085224333 CRLS1 essential 2.8706759240722e-20 1 2.60144439211426e-14 9.08255555663318 -3.7296179408471 1.90171002355939e-20 107.448012631411 24.7242500239207 4.34585528489056 1.65751209866176e-05 -327.72474557585 51.2336232769129 -6.39667321213118 3.43937041447005e-10 PPP1R13B other 2.27178279414405e-16 4.86670913647512e-06 0.146656670489592 4.34585528489056 -6.39667321213118 8.4108354608233e-22 408.652161650458 48.2609380673532 8.46755529451461 2.40581164775297e-16 -669.378345559179 194.882205458995 -3.43478433027084 0.000638867349699926 ATRN other 1.03234594446145e-17 1 3.14968860923819e-12 8.46755529451461 -3.43478433027084 0.291014283741508 21.615206563739 17.9321927785735 1.20538557836419 0.228576622373533 91.6971326779519 71.1441035099157 1.28889293917621 0.197981122458183 SMOX other 1 1 1 1.20538557836419 1.28889293917621 0.000100074534998628 87.2455854480828 21.8889052259816 3.9858359542132 7.67062655915766e-05 234.82464689616 86.9099449711777 2.70193068208748 0.00711555554470919 SIGLEC1 other 0.543805023182543 1 0.640650730220848 3.9858359542132 2.70193068208748 6.51713234795174e-39 328.856479460721 28.1900759169553 11.6656826476627 3.09096730452496e-28 -482.306834180936 103.501865320302 -4.65988542997138 3.97843292484092e-06 NSFL1C other 9.49937211037445e-35 0.0491057975913115 4.50817581364965e-24 11.6656826476627 -4.65988542997138 0.152293507197987 46.4214994729706 24.3260862946523 1.90830119200784 0.0568822755358337 83.1276423118868 95.3133730117073 0.872150881720199 0.383513682442796 SLC4A11 other 1 1 1 1.90830119200784 0.872150881720199 1.37781357669511e-09 44.6770006839752 12.3387430054826 3.62087132085688 0.000321218987520697 -204.347860204622 48.3930978527917 -4.2226654062576 2.83227299424542e-05 C20orf194 other 1.12016243785313e-05 0.331970717655505 1 3.62087132085688 -4.2226654062576 1.14296962892905e-23 57.6084237263348 6.48391913557068 8.88481526709608 9.18253622466845e-18 -81.3822791061301 24.1348693034193 -3.37197927542124 0.000798960308280248 ZNF343 other 1.44745673807575e-19 1 1.23018437801883e-13 8.88481526709608 -3.37197927542124 1.98607962140608e-05 72.6437531572861 33.6660527783714 2.15777458781731 0.0313799690325817 -425.569786236406 125.199546547479 -3.39913200943598 0.000725273926766514 EBF4 other 0.117556052791026 1 1 2.15777458781731 -3.39913200943598 0.0133547361154851 -88.9735940213834 39.7567170719971 -2.23795123375648 0.0256266584858383 -365.220589831531 147.683447899614 -2.47299609418508 0.0137019001243801 CPXM1 other 1 1 1 -2.23795123375648 -2.47299609418508 3.07897519502981e-21 447.080843956177 56.3107166589191 7.93953390194267 1.16166712964762e-14 -915.86574838686 227.051406323126 -4.03373739550176 6.27210192600364e-05 MAVS other 3.73726009172718e-17 0.717967507469636 1.47694358863398e-10 7.93953390194267 -4.03373739550176 5.62690625703052e-06 112.565266567634 23.1036484443859 4.87218574324295 1.448987109451e-06 32.3398921872884 90.6022663610109 0.356943523448166 0.721272247620891 LZTS3 other 0.0349430878561595 1 0.0138001532304113 4.87218574324295 0.356943523448166 7.89811854679664e-18 352.454005740413 51.701381034292 6.81711007887083 2.49637876724068e-11 -932.825024905796 218.187810852627 -4.2753306028441 2.25745830620692e-05 XRN2 essential 8.88064449401814e-14 0.26653810221385 2.9280026560966e-07 6.81711007887083 -4.2753306028441 7.30946692088652e-10 27.9115410788362 7.70735709381221 3.62141532293148 0.000320455725990598 -145.629576866218 32.8887214192569 -4.42794887067117 1.15069214463631e-05 KIZ other 6.02957926303929e-06 0.138382514292732 1 3.62141532293148 -4.42794887067117 1.2412827977318e-05 427.651196603615 101.042769279558 4.23237802816368 2.71405340416837e-05 -199.77060899368 226.032542230746 -0.88381348553671 0.377187327971484 DYNLL1 essential 0.0748369398752505 1 0.236068365094565 4.23237802816368 -0.88381348553671 0.106932376030372 -20.4359448818351 9.65974699851016 -2.11557765280882 0.0348370932318042 -16.1585106190642 21.1844032947768 -0.762755051167678 0.445941937608362 TESC other 1 1 1 -2.11557765280882 -0.762755051167678 9.71679999978321e-78 423.61444628366 20.1281307548801 21.0458910190135 2.37751495533443e-72 -449.773232513812 124.968621298862 -3.59908933810016 0.000348552621635824 SNX5 other 1.50989355196631e-73 1 3.69370723460757e-68 21.0458910190135 -3.59908933810016 3.19147307724197e-05 90.899903996307 177.582914835479 0.511873026076415 0.608949139823212 -1657.67789234664 395.043543575744 -4.19619031700186 3.17338547036121e-05 RPL6 essential 0.184658632249221 0.370524487519375 1 0.511873026076415 -4.19619031700186 0.510667808091497 2.7859831348925 2.76394835981351 1.00797220939413 0.313912658076374 8.64655755539136 10.2483740210085 0.843700428737911 0.399204958829044 SIRPG other 1 1 1 1.00797220939413 0.843700428737911 1.07242811244875e-21 148.919879511717 21.0032964265168 7.09030984887231 4.22724012405971e-12 -231.339032949124 46.7138448092151 -4.95225845558078 9.83524669178144e-07 MAPKAPK5 other 1.31350995212723e-17 0.0124966644465775 5.06677001269797e-08 7.09030984887231 -4.95225845558078 0.850055375096234 5.98494573105123 10.5407145493642 0.567793170284861 0.570410539115278 2.85923955619043 23.3047805893806 0.122688971270269 0.902398875892314 P2RX7 other 1 1 1 0.567793170284861 0.122688971270269 1.81335059446442e-22 107.613739524636 11.1738386763551 9.63086568918852 2.33831553036606e-20 -70.4122409430484 46.0537923391089 -1.52891298124985 0.126874825675641 ESF1 essential 2.25345078374093e-18 1 3.22664160035213e-16 9.63086568918852 -1.52891298124985 5.51469221192506e-19 98.3173468296761 13.8112037050991 7.11866604308916 3.46852085044397e-12 -417.152055311203 84.6385171261768 -4.92863142544574 1.10155114115573e-06 RBBP9 other 6.3733297893218e-15 0.0139621607141489 4.16534668929816e-08 7.11866604308916 -4.92863142544574 2.46458942509374e-22 450.250530261682 60.5261794383745 7.43893856244652 3.99971124818384e-13 -622.285845853174 133.069021260695 -4.67641408915194 3.69003428532809e-06 ANAPC5 essential 3.0551050513462e-18 0.0455977536637992 4.90644578814711e-09 7.43893856244652 -4.67641408915194 0.000195279374585891 80.774859369746 21.0024906006047 3.84596574310193 0.000134238999410634 -49.5639365177059 87.2820092665735 -0.567859710542749 0.570363662323985 SLC23A2 other 1 1 1 3.84596574310193 -0.567859710542749 6.12062870006192e-12 -35.9260191003772 20.1985351944154 -1.77864477570187 0.0758574174778474 -331.065862479157 45.0728445614881 -7.34512910600793 7.57609466022653e-13 SLC8B1 other 5.60588382638671e-08 1.11421624167952e-08 1 -1.77864477570187 -7.34512910600793 9.59401093125124e-26 365.224803570909 44.7795328221758 8.15606551817446 2.39018317764869e-15 -1028.78262060351 186.137515058939 -5.52700308843038 5.05200883205774e-08 TMEM230 other 1.25249812707485e-21 0.000675150460316196 3.07425360309174e-11 8.15606551817446 -5.52700308843038 5.608140249284e-13 16.5945862952933 3.25785752778708 5.09371148178025 4.85182729179019e-07 -94.9011847434467 19.964967286555 -4.75338543666714 2.56538231151173e-06 DZANK1 other 5.34567928561751e-09 0.0319846042405669 0.00476400921780879 5.09371148178025 -4.75338543666714 0.0185286684606769 -0.259181033318832 4.5299091299673 -0.0572155038617085 0.954394575670836 -54.8802776857226 19.9061779438853 -2.75694700612181 0.00603067986897577 CFAP61 other 1 1 1 -0.0572155038617085 -2.75694700612181 7.78323484434223e-22 34.3165471914692 4.29646841848972 7.98715220244351 8.45948493006206e-15 -75.3413235234695 17.7272842535683 -4.25002061487812 2.5204315488017e-05 TASP1 other 9.56248232975887e-18 0.296427954454568 1.07799216463781e-10 7.98715220244351 -4.25002061487812 0.0104130717936179 385.170761609493 127.064452052619 3.03130226737208 0.00255137357537326 219.741403182861 282.119186102106 0.77889563704941 0.436381120970288 OAS1 other 1 1 1 3.03130226737208 0.77889563704941 2.24023150643025e-15 640.168386459762 86.1654826047287 7.42952243877562 4.24671812411741e-13 -326.364722431558 193.980597724303 -1.6824606494687 0.0930533781308043 GCN1 other 2.34081790106897e-11 1 5.20350371748106e-09 7.42952243877562 -1.6824606494687 0.00253670093291907 210.258254538127 774.718742734874 0.271399467884156 0.786186768216603 -5630.20481486434 1744.09055971195 -3.22816082198978 0.00132096608678313 RPLP0 essential 1 1 1 0.271399467884156 -3.22816082198978 9.41660959138699e-12 520.758566871876 86.9382151293152 5.98998456659456 3.82180222088494e-09 -429.927418141775 195.681390164762 -2.19707871954395 0.0284365363612108 PXN other 8.54839818706111e-08 1 4.1554455547682e-05 5.98998456659456 -2.19707871954395 3.1543764666139e-05 3.5795881459371 1.04526806752621 3.42456471898997 0.000662226938994836 -4.49031695516777 2.35316646981484 -1.90820199623237 0.0568912205288526 SIRT4 other 0.182575309887613 1 1 3.42456471898997 -1.90820199623237 3.26345733861586e-06 50.4821440809188 37.9259966090209 1.33106967764985 0.183725712015456 -1055.42062627813 231.293118693132 -4.56313024893064 6.23924086139275e-06 KIF16B other 0.0207751694176286 0.0762372840853581 1 1.33106967764985 -4.56313024893064 3.56432671016413e-21 108.743605789876 11.424543247969 9.51842042430959 5.58876507529532e-20 -47.6443246683874 46.5509386958844 -1.02348794681985 0.306529609807931 TRMT6 other 4.32210256874503e-17 1 7.68287534900847e-16 9.51842042430959 -1.02348794681985 0.720063257832476 -1478.47286519266 2168.98524594355 -0.681642656609909 0.495753429404019 -5248.34335299216 8837.84121821637 -0.593849020751174 0.552858593873361 CHGB other 1 1 1 -0.681642656609909 -0.593849020751174 6.11204764329984e-17 635.611917424206 207.501131672505 3.0631732574229 0.00229904491940782 -3297.15061735122 464.342274586595 -7.10069015423305 3.92303623218666e-12 PEBP1 other 6.70186024087827e-13 5.72527907725321e-08 1 3.0631732574229 -7.10069015423305 0.669779803675392 -1.61578137846498 4.25617469624196 -0.379632297492782 0.704367081483592 -8.42068517656765 9.46903529558036 -0.889286491570898 0.374243647258193 TBX5 other 1 1 1 -0.379632297492782 -0.889286491570898 1.37983800851707e-30 91.9440183776686 12.8915035051147 7.13214081981902 3.21750932422859e-12 -215.331665509007 28.4939176780314 -7.5571098345324 1.79485764100101e-13 BRAP other 1.89810516451609e-26 2.6578251947943e-09 3.86615920399307e-08 7.13214081981902 -7.5571098345324 1.42629046222841e-09 304.083958197196 91.9985083311994 3.30531400685843 0.00101192301493119 -887.705094086513 204.615692393751 -4.33840182882094 1.71440836521698e-05 ERP29 other 1.15857574246814e-05 0.204117459962734 1 3.30531400685843 -4.33840182882094 5.94237493990689e-09 664.854598559288 129.967274920454 5.11555388820926 4.42140713185431e-07 -1746.89770732235 766.287831036229 -2.27968869733983 0.02303425422108 FUS other 4.66060466536897e-05 1 0.00435325659594516 5.11555388820926 -2.27968869733983 3.97201345823919e-20 866.975625404055 87.9984744658098 9.85216653660176 3.46232812541136e-21 799.447963856887 471.811279506108 1.69442316998811 0.0907551427028981 FXYD5 other 4.71398557223827e-16 1 4.81125116307163e-17 9.85216653660176 1.69442316998811 2.49612081919078e-10 49.7312752568398 18.8982940504082 2.6315219312489 0.0087415262782299 -466.547700887174 84.7324300909799 -5.5061291218277 5.66191958274488e-08 ZNF302 other 2.11371510969076e-06 0.000755526549121477 1 2.6315219312489 -5.5061291218277 3.56862068086188e-10 230.835677113292 46.7605015155264 4.93655263805598 1.05798202394683e-06 -882.424634375489 249.734096898974 -3.53345676594759 0.000444918638562364 GRAMD1A other 2.99478647537929e-06 1 0.0101640333040572 4.93655263805598 -3.53345676594759 9.26445241387193e-07 74.970478947832 14.0490402909838 5.33634165715543 1.39421053527025e-07 112.927842268041 70.6559067166694 1.5982788632362 0.110561563315897 CDIP1 other 0.00620996245301835 1 0.00141094106169349 5.33634165715543 1.5982788632362 4.95542504822117e-12 4.00911022817947 0.945576577264754 4.23985780165635 2.63339701410133e-05 -4.89303967817555 2.05349500096369 -2.38278626238646 0.0175290558096865 CMTM1 other 4.55750441684901e-08 1 0.229237210077521 4.23985780165635 -2.38278626238646 1.91935747739167e-27 1667.16539257109 263.076900272563 6.33717894214127 5.11303197512532e-10 -4320.46603601941 657.518521457498 -6.57086590723313 1.22693136785753e-10 GANAB other 2.56023093909275e-23 1.75144452761663e-06 5.75574009439858e-06 6.33717894214127 -6.57086590723313 5.49306986860167e-05 37.6019284442886 13.7044138393293 2.74378232335465 0.00627936349780198 -107.062805688668 42.9688887711407 -2.49163543090215 0.0130202713894312 GMIP other 0.3087654573141 1 1 2.74378232335465 -2.49163543090215 1.8281653523983e-32 506.389313500467 43.8284789036088 11.5538874760897 9.78017889820228e-28 1025.10681590528 129.632605944674 7.90778530166084 1.495875086812e-14 BIRC5 other 2.5588830437519e-28 2.23723077983602e-10 1.42233141716556e-23 11.5538874760897 7.90778530166084 0.000475686135663419 29.8859942325601 7.67501725361633 3.89393186295163 0.000111182871031823 42.1485519728002 28.5556403298417 1.4760149478684 0.140531500990415 LAG3 other 1 1 0.914479114236742 3.89393186295163 1.4760149478684 5.35561780682321e-52 1428.91118113879 90.2232364828254 15.8375074630669 1.45098531646207e-46 -1008.64166402201 335.684234349293 -3.00473349895984 0.00278341088139566 MLF2 other 8.12822114541558e-48 1 2.21507418411099e-42 15.8375074630669 -3.00473349895984 1.37252741257377e-19 42.9886825029321 5.26875264220694 8.15917645450999 2.33595296523206e-15 -16.3766103096957 10.9177250935913 -1.50000207637658 0.13419185734611 OTUB2 other 1.61189619332664e-15 1 3.00543708506756e-11 8.15917645450999 -1.50000207637658 1.41235327471695e-35 387.789060085798 62.1776067255904 6.23679617964768 8.95410915728723e-10 -1106.44253922728 128.842263682944 -8.58757450854807 9.30804247870692e-17 DDX24 essential 2.02347853668698e-31 1.41379857209079e-12 9.98562253220672e-06 6.23679617964768 -8.58757450854807 1.50507498585505e-29 59.242166332836 10.4002298628594 5.69623624804657 2.0108416977892e-08 -155.638712641869 20.5762742584343 -7.56398902381817 1.68512342282248e-13 ZBTB25 other 2.04976162323599e-25 2.49583630154237e-09 0.000212586184290274 5.69623624804657 -7.56398902381817 6.80885258663233e-22 154.154452806777 20.8540812633801 7.39205198540552 5.47665378571978e-13 -393.230968828778 74.5654144415544 -5.27363754059195 1.93184601104165e-07 NECAP1 other 8.37488868155777e-18 0.00252299089042039 6.69739991455672e-09 7.39205198540552 -5.27363754059195 7.105089488298e-07 1.35666167446573 3.984637035321 0.340473087621252 0.733631241641609 -47.2963237879346 9.68696312154299 -4.88247175038289 1.37772470006349e-06 ANKRD24 other 0.00480872456568009 0.0173855079901012 1 0.340473087621252 -4.88247175038289 1.14800812014001e-19 178.498366481874 36.5515201730905 4.88347312605852 1.37717084960981e-06 -416.202574757748 70.2343918091055 -5.9259084337054 5.55548813999612e-09 DHX32 other 1.35097595578076e-15 7.64824052233266e-05 0.013143718588676 4.88347312605852 -5.9259084337054 1.08905452161239e-13 229.186777494763 37.3265365638797 6.14004937486066 1.6035151954101e-09 -182.873744517629 78.5329352423729 -2.3286248496027 0.0202485068382806 RCOR1 essential 1.06966935112769e-09 1 1.76883761205688e-05 6.14004937486066 -2.3286248496027 1.0713033699135e-06 -3.39476703847432 28.1251528725018 -0.120702171962003 0.903971342367074 -282.035783409201 58.1824198241432 -4.84743990129073 1.63260172274943e-06 GPATCH2L other 0.00712631001666462 0.0205250688584058 1 -0.120702171962003 -4.84743990129073 0.0064169299073853 16.0289494017425 62.6868977318901 0.255698558737072 0.79827990649738 -736.700388405411 247.363272822188 -2.9782124888644 0.00302814298502363 LTBP4 other 1 1 1 0.255698558737072 -2.9782124888644 3.2924368350132e-06 247.094190814445 79.0260357007608 3.12674409924964 0.00186183032425 -887.600395877099 306.338864989887 -2.89744625092347 0.00391341212395997 BLVRB other 0.020949775581189 1 1 3.12674409924964 -2.89744625092347 2.06507404999637e-11 30.8447119006738 88.4350878809594 0.348783640518266 0.727386943181222 -806.011391857571 137.212838126941 -5.87416893973067 7.41342552097232e-09 SLC9A1 other 1.84349160443176e-07 0.000101764092126387 1 0.348783640518266 -5.87416893973067 3.58909940795019e-19 212.400121656217 34.8815845377111 6.08917640844518 2.14607140276333e-09 -382.353365241842 76.7850714870645 -4.97952737214361 8.57121194593999e-07 SPTLC1 essential 4.16802114245256e-15 0.0109171526555438 2.35552797167303e-05 6.08917640844518 -4.97952737214361 5.82762253936717e-16 644.868166218793 102.638757301527 6.28289140645312 6.81319403900598e-10 -643.085786992784 212.830364577921 -3.02158852317963 0.00263281348478733 PAPOLA other 6.20700076667997e-12 1 7.6335026013023e-06 6.28289140645312 -3.02158852317963 1.84311187287635e-27 305.918890495593 30.411369428839 10.0593592541575 6.10794050250323e-22 -112.027612009262 62.5272588474028 -1.79166037460021 0.0737451274533043 CCNK essential 2.45963279435349e-23 1 8.54073320465027e-18 10.0593592541575 -1.79166037460021 2.82154299361552e-05 141.30193675249 30.990116261311 4.55958072441619 6.40023448162228e-06 86.8691158584478 56.7542641124351 1.53061831065861 0.126473018130637 PCBP4 other 0.164157371368551 1 0.0584917429275461 4.55958072441619 1.53061831065861 0.987977524590283 5.97936859007562 49.0494097118142 0.121905006099093 0.903020720212013 -30.2399165761062 346.100288544217 -0.0873732775644388 0.930407998180882 RGS1 other 1 1 1 0.121905006099093 -0.0873732775644388 1.96713097824429e-12 245.59308438455 39.0555195210071 6.2883066822975 6.69834121376265e-10 -596.469640969003 235.017578755984 -2.53797883599298 0.0114336252189299 YPEL3 other 1.83769375987582e-08 1 7.50549133002105e-06 6.2883066822975 -2.53797883599298 8.49993709651277e-25 177.124953370878 20.6317889385554 8.58505066615324 9.56541956324273e-17 -262.978503250147 67.6309128381505 -3.88843640007474 0.000113365382968327 MRPS33 other 1.0953868936276e-20 1 1.26158318619608e-12 8.58505066615324 -3.88843640007474 1.22455216359659e-16 324.610544304901 49.3946645099933 6.57177344000844 1.16577792215265e-10 -576.254796227945 162.14696040886 -3.55390440113644 0.000412567570092354 NDUFB2 other 1.33107584317707e-12 1 1.34064461047555e-06 6.57177344000844 -3.55390440113644 1.72667620941848e-13 355.742328717052 107.490273485362 3.30953040849317 0.000996518802800872 -713.39410213407 166.778208168018 -4.27750189890141 2.23356602491957e-05 NUDC essential 1.6838546394249e-09 0.26380648320325 1 3.30953040849317 -4.27750189890141 5.2018379853798e-31 267.842712438787 26.9284153741203 9.94647136556716 1.66646824378803e-21 -227.296959657515 69.8204921670624 -3.25544768595518 0.00120363335724212 MAEA other 7.18529880920512e-27 1 2.32272343819175e-17 9.94647136556716 -3.25544768595518 0.0758478918894558 176.653129086145 77.8418665653269 2.26938454691208 0.0236370488292959 204.903400328927 287.98040586834 0.711518548323063 0.477069072693508 ICAM1 other 1 1 1 2.26938454691208 0.711518548323063 3.58504325164853e-18 256.794604197448 41.3463408774884 6.21081814611709 1.04519670179663e-09 -523.482536287478 120.683344103785 -4.33765355256726 1.71568171695747e-05 STRN4 other 4.06328802141845e-14 0.204251908403787 1.16288585041893e-05 6.21081814611709 -4.33765355256726 0.201821662016311 -143.615313114357 391.297977392175 -0.367022886424021 0.713750399250543 4018.56762700658 2355.07776147447 1.70634180014958 0.0885381044542449 LYZ other 1 1 1 -0.367022886424021 1.70634180014958 9.14181474095326e-18 38.0082322099176 22.0209690777452 1.72600179745629 0.0849128143649119 -244.255742454815 35.9952349637631 -6.78577991505573 3.01423167347029e-11 MUL1 other 1.02607728652459e-13 4.34652207314416e-07 1 1.72600179745629 -6.78577991505573 2.43232645495883e-12 70.7859962392097 9.47641639465036 7.46970091765595 3.22915842990555e-13 125.107847317847 47.4448359471387 2.63691179072129 0.00860604671326689 TFAP4 other 2.26352299898469e-08 1 3.97477111137074e-09 7.46970091765595 2.63691179072129 5.56855379181949e-38 179.443425347715 12.7362416508746 14.0891976037053 1.37651508390559e-38 54.0282607152995 29.016491043028 1.8619846429805 0.0631512682887016 PDCD7 essential 8.08164211806763e-34 1 2.07495883747928e-34 14.0891976037053 1.8619846429805 2.6203914681611e-27 542.762722329826 46.7133519005392 11.6190061352365 5.26091325212374e-28 172.631854890845 106.140522976143 1.6264462436241 0.104439216862156 SPG21 other 3.48931327900332e-23 1 7.66304624304344e-24 11.6190061352365 1.6264462436241 5.85011583373317e-32 471.564946011129 37.2872035601644 12.6468305742006 2.54612014486562e-32 355.999898955708 152.159365786558 2.33965156936239 0.0196625094102264 DNAJB11 other 8.15213641430718e-28 1 3.77335005469084e-28 12.6468305742006 2.33965156936239 0.134626801765513 -15.4998749829777 14.6121172503542 -1.06075490070421 0.289277261509058 105.160842436942 61.4691932463863 1.71078937078981 0.0876964572941438 P3H2 other 1 1 1 -1.06075490070421 1.71078937078981 0.044596008392403 4.21158087785435 4.82179259257441 0.873447125108659 0.382817989954088 -51.0438410120734 21.4408743967602 -2.38067907434718 0.0176358531349617 THPO other 1 1 1 0.873447125108659 -2.38067907434718 0.00485879807244542 -51.3008844875985 47.27446193488 -1.08517119789253 0.278341993035446 -639.941913818553 210.199075046009 -3.04445637393257 0.00244747613240551 CHRD other 1 1 1 -1.08517119789253 -3.04445637393257 0.0145596599017368 -0.905850916853818 4.37726487421609 -0.20694450596071 0.836130634277513 -45.3406488016065 15.7622936374264 -2.87652608462695 0.00417850049088143 FLT3LG other 1 1 1 -0.20694450596071 -2.87652608462695 3.05653547358973e-25 339.617913576967 39.5996738469163 8.57628057467988 1.08734837818091e-16 -661.673922649304 174.446492756885 -3.79299068839083 0.000166017348542496 RAB11FIP3 other 3.96188128086701e-21 1 1.43214654890208e-12 8.57628057467988 -3.79299068839083 4.87589643173633e-22 287.393157553883 36.5758362632361 7.85745964864661 2.13401968412162e-14 -629.082170467524 165.854261408405 -3.79298165223775 0.000165660576077148 GNPTG other 6.01393065890359e-18 1 2.69569366498243e-10 7.85745964864661 -3.79298165223775 9.29522677784516e-07 29.4966996343709 24.4121368681363 1.2082801187663 0.227483494728675 -268.300804611339 58.4520880664298 -4.59009786453514 5.54950026781517e-06 ZNF268 other 0.00622966098651183 0.0680257742828784 1 1.2082801187663 -4.59009786453514 2.34515587398371e-11 256.706102619479 42.3823299407325 6.05691341128384 2.62565556272696e-09 -180.174803766782 101.446359468902 -1.77605982816973 0.0762945512468478 GOLGA3 other 2.0871887278455e-07 1 2.87246718562329e-05 6.05691341128384 -1.77605982816973 6.32923185659099e-19 850.316920714987 113.946871109712 7.4623981548056 3.41208681989448e-13 -828.859304748328 249.485357595275 -3.3222763561657 0.000953188303433967 PABPC4 other 7.30013602339205e-15 1 4.19447832769629e-09 7.4623981548056 -3.3222763561657 0.437061099296501 5.60806025880382 6.2803483311338 0.892953696692711 0.372274641379393 25.9552743786184 22.9901274928378 1.1289747908838 0.259403342766196 CD209 other 1 1 1 0.892953696692711 1.1289747908838 0.000138882407493124 -5.95700717506288 93.2020232955038 -0.0639149984563721 0.949061302000055 -1089.25093441386 269.577084233484 -4.04059171984533 6.09675012236383e-05 CERS4 other 0.740937643975819 0.698504661519224 1 -0.0639149984563721 -4.04059171984533 6.47548103851551e-77 303.390712167545 14.1385540580901 21.458397437321 1.4395443032146e-74 9.76637956868361 50.663288127312 0.192770345741114 0.847210378178663 MCOLN1 other 1.00564220528146e-72 1 2.2384913914987e-70 21.458397437321 0.192770345741114 1.02331478613055e-26 208.610530473797 39.8010768410629 5.24132880391248 2.28036793304341e-07 -412.15672463449 66.5673565941556 -6.19157415469126 1.17030221022729e-09 USP48 other 1.35323147317905e-22 1.63678467122389e-05 0.00228264830097645 5.24132880391248 -6.19157415469126 5.76488983498596e-11 277.446756248409 56.1406593990438 4.94199318672652 1.03276181114494e-06 -124.644923996309 123.084052450091 -1.01268134673134 0.311665080347625 PDPR other 5.03563127086024e-07 1 0.00992793929053628 4.94199318672652 -1.01268134673134 7.30823397081563e-65 1377.75789702201 115.426346512207 11.936251459508 2.60483144176299e-29 -1408.06128742782 252.810159463899 -5.56963885634072 4.03034580611459e-08 AARS essential 1.12817207807481e-60 0.000540348462225783 3.81659902847114e-25 11.936251459508 -5.56963885634072 7.93953205254303e-27 746.878095011199 110.435136317732 6.76304770306402 3.48464249605415e-11 -868.025413116005 241.033418652388 -3.60126582433721 0.000345550996497566 GLG1 other 1.05143222971827e-22 1 4.0672747213944e-07 6.76304770306402 -3.60126582433721 5.29887551012174e-19 196.439507559049 25.5482952755902 7.68894775326691 7.04414616370644e-14 -541.724568500857 145.436387820171 -3.72482139181486 0.000215973764517348 TNRC6A other 6.12814952745579e-15 1 8.80447829001668e-10 7.68894775326691 -3.72482139181486 1.27902537707384e-29 179.109525411183 14.6507931096424 12.2252443311961 1.66040422406765e-30 124.251467102474 82.4685277860413 1.50665314924543 0.132485414329985 PLEKHG2 other 1.74395110164018e-25 1 2.44544334120684e-26 12.2252443311961 1.50665314924543 1.14727538973412e-27 20.4460511269097 1.73157355182118 11.807786683624 8.69588695013405e-29 25.6857733856124 9.15273048692332 2.80635089411954 0.00519114369324769 DLL3 other 1.53425137869144e-23 1 1.27090387776209e-24 11.807786683624 2.80635089411954 4.35025214770637e-11 119.329897603221 18.2319111751282 6.54511183479268 1.39862261071669e-10 -118.604579312213 79.3990512956724 -1.49377829302449 0.135825308215119 NAT14 other 3.82082646133051e-07 1 1.6039404099699e-06 6.54511183479268 -1.49377829302449 0.312742697340203 20.8356750863746 15.9437890759899 1.30682079316713 0.191842461179344 40.9016287794961 36.4048935645727 1.12352007586418 0.261727247080983 PITPNM2 other 1 1 1 1.30682079316713 1.12352007586418 8.90642819228603e-26 153.661327816135 21.5977140705666 7.1147033113817 3.6343420900024e-12 -309.052992398027 52.9593031626622 -5.83566954136054 9.30862942675062e-09 EXOC1 essential 1.16344671475832e-21 0.000127397902334509 4.36375454746588e-08 7.1147033113817 -5.83566954136054 7.02854991482954e-06 72.6745926838417 24.4566541513111 2.97156725667422 0.00309312872324521 -150.374496277649 57.258008186967 -2.6262613918847 0.00887469794506579 RBM27 other 0.0432818103755203 1 1 2.97156725667422 -2.6262613918847 0.0120341553312967 159.88963076959 111.143712107381 1.43858458331061 0.150859617709011 -775.574067344055 344.89699381118 -2.2487121698969 0.0249415465751903 OSBPL8 other 1 1 1 1.43858458331061 -2.2487121698969 1.54612433110353e-07 72.5524216603676 18.7265362710526 3.87431079673387 0.000120082964590195 -202.880156875772 63.9288831627108 -3.17352887832256 0.00159188249150457 DTX2 other 0.00110486044700658 1 0.984440143710418 3.87431079673387 -3.17352887832256 0.264494120777349 1.21348327822856 2.2499052632865 0.539348610819279 0.589866599689854 11.4007180017993 7.02191392940206 1.62359124825817 0.105041288512323 NLRC4 other 1 1 1 0.539348610819279 1.62359124825817 1.12121953955584e-15 162.283763572461 21.9699049562715 7.38663930934012 5.73567301985594e-13 -125.435720738283 67.0836061037055 -1.86984165019946 0.0620456857513162 PUS7 other 1.18344722400119e-11 1 7.01071313216991e-09 7.38663930934012 -1.86984165019946 0.24448763202355 -4.83184756278158 47.6113284176334 -0.101485249905189 0.919202797496911 -234.22989137712 143.743133649348 -1.62950316603303 0.103787554149473 NRCAM other 1 1 1 -0.101485249905189 -1.62950316603303 0.263099456362863 403.414043329655 250.601758093025 1.60978137743114 0.108027823926566 574.497435316462 750.289704274664 0.765700811357731 0.444187654497669 LAMB1 other 1 1 1 1.60978137743114 0.765700811357731 0.0293065115671756 13.0740962141994 5.33600295384184 2.45016659984909 0.0145941505887277 -4.15522763173328 15.9757381939858 -0.260096127094618 0.794888400490794 SLC26A4 other 1 1 1 2.45016659984909 -0.260096127094618 0.0337995321189381 -34.4329116710778 17.1958539996678 -2.0023961398918 0.0457398162197289 -113.398270766946 51.4835662380781 -2.20261102819787 0.0280423704394821 SLC26A3 other 1 1 1 -2.0023961398918 -2.20261102819787 8.33392841148602e-22 391.374921862323 48.0779724787868 8.14042068922535 2.71774428341966e-15 -513.913858932762 143.94315517868 -3.5702556213585 0.000388324593787974 DLD other 1.02307305179402e-17 1 3.49121430648089e-11 8.14042068922535 -3.5702556213585 2.71417108737121e-17 124.937835602026 20.5374119701514 6.08342646987889 2.22439683115772e-09 -150.292645046713 42.731240900305 -3.51716079103239 0.000472772521098994 WDR7 other 3.00784439902477e-13 1 2.44016332378002e-05 6.08342646987889 -3.51716079103239 4.09525394850216e-43 488.941771544967 44.3042207262794 11.036008839107 1.10237133713593e-25 -461.192903946745 92.1817379671028 -5.0030831932387 7.63596779550568e-07 TXNL1 other 6.07694733418236e-39 0.0097518944716403 1.58498950853405e-21 11.036008839107 -5.0030831932387 2.52032943811763e-06 154.79888081303 122.266600056043 1.26607659607837 0.206026565473135 -1044.60743403752 249.628556431029 -4.18464717727973 3.32901253864013e-05 CMTM6 other 0.0162233605931632 0.388129571880053 1 1.26607659607837 -4.18464717727973 0.116989271185219 545.447774500336 262.906350461217 2.07468466829902 0.0384870975742905 354.493833443154 646.532575234439 0.548300034711493 0.583711661103746 ITGA6 other 1 1 1 2.07468466829902 0.548300034711493 3.95792061514507e-05 -54.3078233340659 18.3711905970574 -2.95614065115435 0.00325052526641068 -188.415059223984 45.1953244560039 -4.16890599839369 3.56170204511269e-05 RAPGEF4 other 0.226828430453964 0.414439649969313 1 -2.95614065115435 -4.16890599839369 0.00011619668688515 143.960397382062 121.084822287115 1.18892190336378 0.234990068942326 -1070.23736672884 297.88313397828 -3.59280954391623 0.000356862527171574 MAP3K20 other 0.626183945624071 1 1 1.18892190336378 -3.59280954391623 5.39554544339781e-25 346.238667074839 31.1183658451466 11.1265054469061 4.78692776159264e-26 59.2660881248353 191.248645817196 0.309890236720862 0.756763318934895 FH ts 6.96996560378129e-21 1 6.89700551890267e-22 11.1265054469061 0.309890236720862 3.18061696242328e-08 195.197129524373 65.4236345736905 2.98358736557981 0.00297774022071131 709.590776198397 118.845461751697 5.97070149536666 4.28420825864637e-09 SEL1L3 other 0.000238609884520994 5.91520634271305e-05 1 2.98358736557981 5.97070149536666 0.577824950185014 138.716497663971 132.873128091617 1.0439770603453 0.296959688915208 40.0144726723457 464.55549929087 0.0861349671533898 0.93139081984238 TF other 1 1 1 1.0439770603453 0.0861349671533898 8.40876239391331e-05 777.655899743307 189.021821333423 4.11410647859311 4.48765826763977e-05 -495.828048335494 654.417385384229 -0.757663319174165 0.448980028121698 CDV3 other 0.461641055425841 1 0.382931879977702 4.11410647859311 -0.757663319174165 5.82578594809844e-07 4.3690049180139 3.88077183800865 1.12580824134608 0.260763035840076 -33.3182271975121 7.8645016341094 -4.23653382599687 2.68279651370908e-05 MYO15A other 0.00396969054503428 0.314993338483313 1 1.12580824134608 -4.23653382599687 2.58561567729169e-63 623.423640419083 45.8417230577731 13.5994809713719 2.78500812365577e-36 -611.770301549333 92.718313183662 -6.59816039079034 1.022113642884e-10 ALKBH5 other 3.98624368968061e-59 1.46070260704552e-06 4.17584118060946e-32 13.5994809713719 -6.59816039079034 0.252602829611813 -29.4831900327872 18.2016301213496 -1.61981041457407 0.105852525968871 -33.2255685245905 33.1187788610732 -1.003224444475 0.316198606770533 NLRP1 other 1 1 1 -1.61981041457407 -1.003224444475 2.5394234764999e-06 67.6251711061813 14.2481960508439 4.74622688127429 2.65288165039245e-06 95.9300328020165 26.107027154595 3.67449086538879 0.000261915854702964 PITPNM3 other 0.0163361112243238 1 0.0248734183540796 4.74622688127429 3.67449086538879 2.50921413228856e-42 129.896985573261 22.7393801515867 5.71242420450046 1.83680637655008e-08 -439.935512953795 42.3618007847812 -10.3851938492626 3.61761365508274e-23 SPAG7 other 3.71162954448124e-38 5.61670696088147e-19 0.00019457289946795 5.71242420450046 -10.3851938492626 4.27679237915339e-19 35.3753518894943 9.4711028880853 3.7350826305558 0.000210294242596175 -131.972693292329 24.8049699203531 -5.3204133573265 1.59408635747821e-07 ORC6 essential 4.95894076362836e-15 0.00209096307510416 1 3.7350826305558 -5.3204133573265 0.0822957939569864 -15.6142039707001 8.97015415230169 -1.74068401786535 0.0823373871877651 -137.201257426032 89.6991951743422 -1.52957066291802 0.126738198743686 ZFHX4 other 1 1 1 -1.74068401786535 -1.52957066291802 1.86396583666286e-44 81.7303581103135 6.24480199384725 13.0877421239039 3.20440648573505e-34 -98.9326666013697 23.123272621487 -4.27848895875741 2.22334027075371e-05 ZC3HC1 other 2.77749549321133e-40 0.262665419586843 4.7784109515281e-30 13.0877421239039 -4.27848895875741 0.0722515185664631 457.780993891408 859.914691797397 0.532356288662253 0.594696613214435 -3314.48837822335 1885.04310481214 -1.75830906453127 0.0792572221034885 ESR1 other 1 1 1 0.532356288662253 -1.75830906453127 0.330903188548066 0.73545168165937 1.48086292962406 0.496637242344957 0.619646249190185 -3.26933264855164 3.19925826145808 -1.02190332301014 0.307282554908629 RGS17 other 1 1 1 0.496637242344957 -1.02190332301014 0.870802676949948 -7.41672023720431 15.9986809011114 -0.463583234333342 0.643135263891078 -16.5691672661964 34.7727995008345 -0.476497938159934 0.633914586500048 ANGPT2 other 1 1 1 -0.463583234333342 -0.476497938159934 9.69702389613304e-16 231.686288891479 89.9196699993122 2.57659185018419 0.0102438654227693 -1374.43607977446 209.735661749854 -6.55318255516179 1.32232738450067e-10 TMEM101 other 1.02604209844984e-11 1.88577108303641e-06 1 2.57659185018419 -6.55318255516179 0.27717303011096 -18.7870030232689 12.1394227665681 -1.54760266484896 0.122298449210432 -26.2046734799749 40.7160198084731 -0.643596147247224 0.520108071815684 CD200 other 1 1 1 -1.54760266484896 -0.643596147247224 0.0507248424615929 -780.836787544351 355.852056562233 -2.19427364025307 0.0286378363682603 -1659.62112248042 1201.23564764733 -1.38159496492704 0.167663238050602 CCDC80 other 1 1 1 -2.19427364025307 -1.38159496492704 0.00801361545890621 -3.55045124578347 2.1867657226344 -1.62360842271949 0.105044054722904 -18.0485630036373 5.94550012452846 -3.03566775302503 0.00251599082372949 CMA1 other 1 1 1 -1.62360842271949 -3.03566775302503 1.9943233824046e-35 1184.51285493614 105.396522675352 11.2386331623553 1.98861537102913e-26 -1494.96252474603 325.870588908262 -4.58759573778808 5.60451239106402e-06 PSME1 other 2.85467448957395e-31 0.0686822626086336 2.87275376498867e-22 11.2386331623553 -4.58759573778808 5.00717025632552e-23 103.843637107489 9.82274957686205 10.571748398442 8.12245652512332e-24 103.270427825757 25.695941004971 4.01893932608961 6.69988615738283e-05 PPP2R3C essential 6.27548648225278e-19 0.764993001449971 1.15476964417678e-19 10.571748398442 4.01893932608961 0.852994698878463 -0.311061727209254 3.05777390487792 -0.101728164634093 0.919010207542112 5.0877328918984 10.1149608842776 0.50299086176464 0.615175782176267 JPH4 other 1 1 1 -0.101728164634093 0.50299086176464 0.853447100403637 377.592230476263 1258.68499547374 0.29998945870817 0.764301500260711 -1538.92570707141 4136.88846740526 -0.37200077285058 0.710039296780242 MYH7 other 1 1 1 0.29998945870817 -0.37200077285058 1.3025338714898e-16 -212.426892364651 133.336148305324 -1.59316805730895 0.111707631277827 -3921.58959996819 445.485941806886 -8.80294804379745 1.80588019186578e-17 SLC7A8 other 1.41403077088932e-12 2.75468964467206e-13 1 -1.59316805730895 -8.80294804379745 9.13563171322555e-27 76.7614003910038 11.2406869234026 6.8288887426613 2.28314430058233e-11 -206.104286827096 31.4546561667647 -6.55242536222245 1.30898521877927e-10 OSGEP essential 1.20900950092827e-22 1.86739831311051e-06 2.6801830944536e-07 6.8288887426613 -6.55242536222245 0.000357198658913625 195.333860024576 76.1058805380666 2.56660666223911 0.0105377937653103 -559.296097877861 250.940250864956 -2.22880186000471 0.0262370976116297 SLC22A17 other 1 1 1 2.56660666223911 -2.22880186000471 1.31105070205433e-48 256.833186975716 19.6271612931456 13.0856002628057 4.19602647673799e-34 -386.830780050701 60.7645548358429 -6.36605963946803 4.20478446681278e-10 RNF31 other 1.97496677757464e-44 5.93883758092636e-06 6.25459706622565e-30 13.0856002628057 -6.36605963946803 5.56080568665525e-94 421.05358826353 16.9981160672611 24.7706032008154 1.64834073282741e-90 -141.244455192249 71.5723352583857 -1.97345042162363 0.0489642817822563 SCFD1 essential 8.67819335459418e-90 1 2.57157637728405e-86 24.7706032008154 -1.97345042162363 4.69797420929293e-69 210.430300038175 10.2199413116087 20.5901671665325 1.27129955593069e-69 94.2384689139225 41.9243248165613 2.24782317488142 0.024998584560833 G2E3 other 7.26541711467152e-65 1 1.97229413107088e-65 20.5901671665325 2.24782317488142 6.12483328731806e-71 1250.48490458887 61.6629791020587 20.2793462592716 4.78185581559359e-68 -475.063719493789 258.603340276855 -1.83703628493428 0.0667663970309719 HECTD1 essential 9.48369186208328e-67 1 7.41570199882254e-64 20.2793462592716 -1.83703628493428 2.12629221422922e-08 390.295340453488 124.830067376912 3.12661323233152 0.00186246914526332 -1305.98963422167 343.562020204826 -3.80132132603906 0.000160136218690136 HNRNPC essential 0.000161343053215713 1 1 3.12661323233152 -3.80132132603906 3.60647925801747e-12 4.61443434170561 0.843114282646341 5.47308287462758 6.75483930024985e-08 -6.79621151842174 2.33184909221391 -2.9145160126847 0.00370877684300143 RPGRIP1 other 3.33382942611135e-08 1 0.000697031867392782 5.47308287462758 -2.9145160126847 1.3426007905055e-30 787.666639195255 75.0682116290175 10.4926788863421 1.38629599915013e-23 -603.264452879057 207.620419608848 -2.90561233820639 0.00381426587986504 SUPT16H essential 1.84741868773557e-26 1 1.96715402279404e-19 10.4926788863421 -2.90561233820639 1.37260983954215e-58 302.756424105542 30.725894167295 9.85346178884518 3.38066596983756e-21 -975.280266380657 85.5901133898124 -11.3947771273398 3.84409799303125e-27 TOX4 other 2.10475992795393e-54 6.00025255732249e-23 4.69844956488024e-17 9.85346178884518 -11.3947771273398 1.75929921773079e-15 45.9429684200844 5.46705440281814 8.40360549483499 3.97384985015975e-16 16.6760865731492 12.354407484036 1.3498086893036 0.177651405866804 GEMIN2 other 1.84480115971251e-11 1 5.18309235956336e-12 8.40360549483499 1.3498086893036 7.41580810122272e-13 13.0684370876246 4.4408684819294 2.9427660694754 0.00339432400736431 93.536420312001 12.2258397501692 7.65071538834022 9.39069774921118e-14 TGM1 other 7.03760188806036e-09 1.39545768553278e-09 1 2.9427660694754 7.65071538834022 2.36005009098584e-55 183.689374259734 18.8009968390663 9.770193348368 7.46036761367227e-21 -582.176166339174 51.7596896717817 -11.2476749770114 1.73448457769469e-26 TINF2 other 3.60120043383529e-51 2.70579594120372e-22 1.03423076228339e-16 9.770193348368 -11.2476749770114 0.297111328460178 0.674104890383455 62.051506449332 0.0108636345667755 0.991336263874509 -202.019570851596 140.500355408256 -1.43785807704601 0.151054638500265 SEMA6A other 1 1 1 0.0108636345667755 -1.43785807704601 2.76146988237905e-16 104.563657512617 35.9260847195453 2.91052193215284 0.00375714442679856 -479.171382070136 74.0172816687997 -6.47377708646816 2.14943111677728e-10 TRPM7 essential 2.97134159343985e-12 3.05434161694051e-06 1 2.91052193215284 -6.47377708646816 0.163651341585867 43.0458471167836 28.631003513106 1.50346972983602 0.133301467287582 85.6876880861944 48.7195328593334 1.75879535490618 0.0791775879869749 TYRO3 other 1 1 1 1.50346972983602 1.75879535490618 0.00438659446521701 77.0209558230936 23.7248235484724 3.24642902678417 0.00124424051790827 40.6357382862385 41.0842365830986 0.989083445765069 0.323084093024406 WDR76 other 1 1 1 3.24642902678417 0.989083445765069 0.471801473341872 77.8737886076125 85.988053885625 0.905634970076129 0.365549321536389 -35.0982630623622 144.338072723644 -0.243167048028712 0.807972069212632 CAPN3 other 1 1 1 0.905634970076129 -0.243167048028712 1.07768955580652e-30 112.864503004128 50.4977303914226 2.23504110242743 0.0258385176719373 -801.615086701454 84.7338937246999 -9.46038298801538 1.05564773153251e-19 SNAP23 essential 1.48343967356768e-26 1.62421959973593e-15 1 2.23504110242743 -9.46038298801538 0.214276886045303 -8.65467479622787 14.159990387555 -0.611206262105542 0.541331155413445 -87.6301456465297 49.9927248430092 -1.75285795926732 0.0802179435074551 TBX15 other 1 1 1 -0.611206262105542 -1.75285795926732 7.21499150475446e-05 573.21767806303 132.088789583647 4.33963911600563 1.72521184713388e-05 95.7758538008638 476.241976014618 0.201107543275278 0.840695617870054 PHGDH other 0.399710529363397 1 0.152336206101922 4.33963911600563 0.201107543275278 0.0690505048844498 155.780846005162 67.5064699488971 2.30764319513506 0.0214137718495435 252.115957484128 487.301898091176 0.517371178876378 0.605118783602128 COL9A3 other 1 1 1 2.30764319513506 0.517371178876378 4.11804550544185e-23 1559.11321099196 308.873049705086 5.0477476506306 6.10671930142014e-07 -3751.72769017679 652.998860904434 -5.74538167644039 1.52799514412369e-08 EZR other 5.1697943275317e-19 0.000207730939843616 0.00595099795923393 5.0477476506306 -5.74538167644039 4.72206978911689e-05 1394.96821901922 519.583484154963 2.68478167909428 0.00748157785814464 -4253.26082103613 1529.48431820031 -2.78084630906238 0.0056117461501373 MYL6 other 0.268024681230275 1 1 2.68478167909428 -2.78084630906238 7.03179319008084e-15 235.732265485655 43.364353442597 5.43608394387114 8.27177761797508e-08 -309.36639376669 84.1640412755078 -3.6757549789463 0.000260924202390393 AGO1 other 7.2279802200841e-11 1 0.000849180690261322 5.43608394387114 -3.6757549789463 0.0131464975069208 4.00138676719813 4.31591948789051 0.927122662604137 0.354284050541509 -19.3304738174612 8.50826396113293 -2.27196451658832 0.0234877749853331 TEKT2 other 1 1 1 0.927122662604137 -2.27196451658832 1.27212205505287e-08 109.121229367542 17.9324351593857 6.08513168443992 2.21490110856195e-09 57.6843937404834 34.6132808837135 1.66653932443675 0.0961891581337406 CLSPN other 9.77116950486107e-05 1 2.42996800620331e-05 6.08513168443992 1.66653932443675 8.21311803366926e-41 227.782276690972 22.150731755951 10.2832845072839 9.20811964557518e-23 -357.767592026764 60.0163852228229 -5.96116528342185 4.53987558811048e-09 RFFL other 1.20683556386736e-36 6.26457432403366e-05 1.29760822045445e-18 10.2832845072839 -5.96116528342185 1.51082448083703e-09 135.26162474904 31.4215546941957 4.30474004438824 1.98616348864102e-05 646.856459411775 115.357864068163 5.60738935864448 3.28459877010264e-08 UNC13D other 1.22573190130308e-05 0.000441482920689495 0.174603632286432 4.30474004438824 5.60738935864448 4.93608315179413e-22 217.201268141237 21.2963335701179 10.1989982184541 1.88012940659179e-22 22.4334934080316 66.6279473361265 0.336697951909858 0.736475659010858 MFSD11 other 6.0876713511077e-18 1 2.64139380332081e-18 10.1989982184541 0.336697951909858 0.000396374800397022 89.9243613627203 111.847628468765 0.803989879748167 0.421753359322811 -561.906091001214 226.438626235212 -2.48149399395109 0.013383674354565 DPYSL2 other 1 1 1 0.803989879748167 -2.48149399395109 0.0543513787477752 72.5847931331287 44.7567254815555 1.62176281558045 0.105446604117196 -446.428438591004 277.309568187036 -1.6098558787914 0.108022492427997 TGFB2 other 1 1 1 1.62176281558045 -1.6098558787914 0.0727993525461099 78.728063967749 36.3140870487037 2.16797585637113 0.0306006884091175 -113.295360950523 225.682328964127 -0.502012547772544 0.615865232707804 GPATCH2 other 1 1 1 2.16797585637113 -0.502012547772544 1.25020323638803e-44 353.937856301476 35.7897052055481 9.88937612837919 2.52728425953301e-21 -409.86966699887 71.1623479901573 -5.75964226272523 1.40861151462925e-08 NUP50 other 1.86430306610182e-40 0.000191754285486479 3.51519967658446e-17 9.88937612837919 -5.75964226272523 8.35057632247926e-15 126.927871796058 16.2156049452592 7.82751381922177 2.66670416509188e-14 56.8816171338164 32.0262122718487 1.77609567597276 0.0762833145625127 CDC45 essential 8.55934073054124e-11 1 3.36324729301388e-10 7.82751381922177 1.77609567597276 0.528036429223719 -50.487259627269 75.7430884461048 -0.66655929488792 0.505338884841202 60.2451527319987 144.239478528059 0.417674504558605 0.676351443756788 ADA2 other 1 1 1 -0.66655929488792 0.417674504558605 4.76783530015987e-05 100.646968436286 36.0500944377333 2.79186421023464 0.00542616329679918 -155.163264988176 83.909404399841 -1.84917609769698 0.0649787042660474 ECHDC1 other 0.27035441447072 1 1 2.79186421023464 -1.84917609769698 8.23259295266425e-06 212.301220485476 67.1187391915109 3.16306925670511 0.00164877443150231 -284.023802745493 132.868311783381 -2.13763386418686 0.0329940427880667 LRRFIP2 other 0.0503999340562105 1 1 3.16306925670511 -2.13763386418686 6.75659649434504e-41 107.313659424434 32.0619289059077 3.34707433664916 0.000872925067704017 -697.757364188518 61.783530610236 -11.2935819189478 1.00155294460471e-26 SEC22C other 9.93219684668721e-37 1.5628232147612e-22 1 3.34707433664916 -11.2935819189478 2.34605758923719e-05 38.4601364279229 8.84394928376492 4.34875135461544 1.63389701121869e-05 5.08024973673243 17.590843877329 0.288800797287493 0.77284343429065 XYLB other 0.137502435305192 1 0.144632563433078 4.34875135461544 0.288800797287493 4.31205768344203e-11 -36.1399811379888 558.004831304558 -0.0647664305226484 0.948383894157138 9491.97878763414 1448.2482880334 6.55411013847873 1.30687128319874e-10 GABRP other 3.78943629220885e-07 1.86451325973965e-06 1 -0.0647664305226484 6.55411013847873 0.000106329518215686 3.24579953377916 2.70664378777564 1.19919715643358 0.230973364154615 -30.3116669956871 8.33320715817369 -3.63745511426002 0.0003015480034282 KRT31 other 0.575455352583293 1 1 1.19919715643358 -3.63745511426002 3.41864759271723e-56 270.807180351086 14.9252187688038 18.1442687404434 2.56827988433087e-57 305.867380721235 113.476800167144 2.69541774416191 0.0072585572414833 CDC6 essential 5.22540284546829e-52 1 3.96259903353409e-53 18.1442687404434 2.69541774416191 1.00164443492819e-13 126.811595187102 20.7346712171741 6.11592023133055 1.83700905524242e-09 -123.705824228028 48.1164283854121 -2.57096855230287 0.0104066210366514 CDC23 essential 9.85217466195364e-10 1 2.0225469698219e-05 6.11592023133055 -2.57096855230287 1.21055894281982e-19 75.3812089623653 17.8669108298677 4.21903985978105 2.87754660963993e-05 -370.39188765486 51.3362394907342 -7.21501791578857 1.83571159492995e-12 AAAS other 1.42398048443895e-15 2.69005177121035e-08 0.249914923047228 4.21903985978105 -7.21501791578857 0.0210818699587449 78.8194318806435 33.3563997766619 2.36294781236524 0.018483021761406 -321.717251283648 242.79385533543 -1.32506339931537 0.185709485755901 FMO2 other 1 1 1 2.36294781236524 -1.32506339931537 7.22436058355464e-12 447.485811217226 61.1534229398276 7.31742868518633 9.31055220994501e-13 -52.7658966125792 454.501525313306 -0.116096192584185 0.907619870443061 SUCO other 6.5972860849021e-08 1 1.13160451559672e-08 7.31742868518633 -0.116096192584185 9.4239885470353e-18 379.173109332162 41.4114728350064 9.15623336660548 1.08329417125291e-18 288.462992284017 144.158403336671 2.00101406235981 0.0458871947723978 MSH2 ts 1.05718303520642e-13 1 1.46851357855045e-14 9.15623336660548 2.00101406235981 7.67554410578059e-15 -295.277096740465 127.299704086622 -2.31954267968716 0.0207397982197448 -2354.85758097214 286.436420940124 -8.22122261283384 1.52222604573374e-15 MAP3K1 other 7.87971357899435e-11 2.29551687696647e-11 1 -2.31954267968716 -8.22122261283384 4.80868628531211e-15 198.55150163324 31.3841027540333 6.32649922125696 5.28225540366945e-10 -323.385044122097 96.5178144901889 -3.35052182677602 0.000863195368172888 DHPS essential 4.9702581444986e-11 1 5.94253732912814e-06 6.32649922125696 -3.35052182677602 1.15632105840667e-11 202.44224389541 45.9522272437268 4.40549361887669 1.2745928529684e-05 -598.025211760636 142.76748744127 -4.18880532590899 3.27782635129727e-05 HOOK2 other 1.04438917995291e-07 0.38239122214234 0.113872125484197 4.40549361887669 -4.18880532590899 1.05464958460155e-38 890.619897796446 132.993345918337 6.69672525077548 5.33351401329859e-11 -1625.34492099842 245.458817397091 -6.62166035929773 8.55147763977253e-11 ARCN1 essential 1.53514793534602e-34 1.22380196502785e-06 6.18794295822902e-07 6.69672525077548 -6.62166035929773 8.34753413046288e-05 102.194733820405 36.3989639749435 2.80762754376069 0.00516891807548323 -169.691025076391 76.2605011984419 -2.22514961755665 0.0264782145397299 EPB41L4B other 0.458363099103717 1 1 2.80762754376069 -2.22514961755665 0.00139026792896479 96.380312885818 27.8896696689606 3.45577104461309 0.000591407810888022 4.56244849766869 59.0066940640581 0.0773208628281337 0.938396619753634 TMEM38B other 1 1 1 3.45577104461309 0.0773208628281337 2.36162303661552e-13 250.912191578093 49.6683833120925 5.05174871510271 6.00949844717459e-07 -467.372242614944 113.801149540524 -4.1069202244615 4.6348310566959e-05 PSMD5 other 2.29077434551705e-09 0.536018211706881 0.00585866003615051 5.05174871510271 -4.1069202244615 0.0287905730800749 -72.6151795300764 45.279765300349 -1.60370043988538 0.109364791052143 -279.761271755427 112.419819100045 -2.48854049041354 0.0131271061124937 PTGS1 other 1 1 1 -1.60370043988538 -2.48854049041354 2.23998359882347e-16 372.813843238021 48.5718986012176 7.67550484898433 7.66160474214109e-14 -148.680606380145 107.299547883485 -1.38565920651963 0.166417752759735 NUP188 other 2.41739029985028e-12 1 9.56704584151158e-10 7.67550484898433 -1.38565920651963 1.80836856985728e-06 455.405086697313 280.357575474203 1.62437232497474 0.104875595113831 -2533.13654473356 620.616783437231 -4.08164363635802 5.14269869030068e-05 CRAT other 0.0117996049183187 0.592850305017862 1 1.62437232497474 -4.08164363635802 7.77658383867885e-08 -24.6757352947307 13.6737777696658 -1.80460262777357 0.0716918220401905 -180.679038149819 31.1124055951735 -5.80729887944918 1.08254920622931e-08 SH2D3C other 0.000566679664324528 0.0001477679666503 1 -1.80460262777357 -5.80729887944918 3.93425887885291e-09 193.396445076981 76.7209360847234 2.52077796422364 0.0119943898375138 -747.206251332938 160.240297402015 -4.66303584957989 3.92512948831185e-06 NANS other 3.12065414270613e-05 0.0484557235332098 1 2.52077796422364 -4.66303584957989 2.35343479336073e-09 41.9407838261263 24.7844326900658 1.69222287032364 0.0911750596219741 -275.729244915185 52.0898429746676 -5.29333991368102 1.74391369956092e-07 TBC1D2 other 1.89098485646534e-05 0.00228260864135528 1 1.69222287032364 -5.29333991368102 5.65455448047812e-12 97.6533996066905 23.3887413779781 4.1752310664582 3.4681249679596e-05 -248.51143696415 54.9988193855219 -4.51848675554606 7.65102547897142e-06 WHRN other 5.18918464673477e-08 0.0930441208497715 0.298987053487797 4.1752310664582 -4.51848675554606 9.07772301897775e-22 119.495732138535 14.779628385677 8.0851648647904 4.03823549505618e-15 -79.8447202504673 29.1706685453864 -2.73715770779259 0.00639962397044009 CWF19L1 other 1.11347350550781e-17 1 5.17297966916696e-11 8.0851648647904 -2.73715770779259 4.23068432370171e-06 65.7007892633038 14.133903002229 4.64845338566018 4.19817265854484e-06 2.52467122373929 27.2631961103916 0.092603640949382 0.926252418458048 SEMA4G other 0.0265940816587889 1 0.0388163044009056 4.64845338566018 0.092603640949382 0.000453698144478955 96.8731975605946 39.0356348461939 2.48166061452027 0.0133791594468906 -143.147826656516 74.7815144327028 -1.91421406402964 0.0561190747768523 BTAF1 other 1 1 1 2.48166061452027 -1.91421406402964 4.5056790352768e-64 203.325270182634 11.2708211912379 18.0399694691901 2.26810311205348e-57 -146.420399297971 41.4947280795909 -3.52865065212918 0.000453024456328952 IKZF5 other 6.95091104772152e-60 1 3.49968310189852e-53 18.0399694691901 -3.52865065212918 2.47320549483258e-09 8.48371376116947 21.1955041805872 0.40026005934502 0.689121823411548 -233.094533100904 40.9251427508593 -5.69563152216518 2.0122864802168e-08 BLNK other 1.98351080685573e-05 0.000272262360773333 1 0.40026005934502 -5.69563152216518 0.201772752051277 2.4819362587637 2.87965468339252 0.861886764783801 0.389128892650656 -6.06320144688698 5.56015454914055 -1.09047354588807 0.275986486437576 TLL2 other 1 1 1 0.861886764783801 -1.09047354588807 0.0123772853504739 1.63431099323372 7.79295822647484 0.209716380575673 0.833967554954549 -39.5895674296751 14.8263637617061 -2.67021422554922 0.00780699524118413 CYP26A1 other 1 1 1 0.209716380575673 -2.67021422554922 4.36134614011008e-05 94.4111566469811 21.6047152195969 4.36993293766464 1.48996275236373e-05 26.6672720096929 41.918505265445 0.636169439745642 0.524934534299653 TDRD1 other 0.249076478061687 1 0.132323592037423 4.36993293766464 0.636169439745642 0.142850427533336 251.455927560084 316.573681713081 0.794304587163961 0.427362598109094 -822.673927588652 615.064591766779 -1.33754070483152 0.181602066884104 SORBS1 other 1 1 1 0.794304587163961 -1.33754070483152 0.85279577663792 -23.8669655895738 48.9031140338133 -0.488045926340629 0.625712878469344 5.35972677359046 93.7885002779526 0.057146950401236 0.954449005076503 CRTAC1 other 1 1 1 -0.488045926340629 0.057146950401236 2.81600843461757e-05 788.159151068056 190.93164710921 4.12796497071667 4.23447218395534e-05 -711.99609687954 702.239636285091 -1.01389334935018 0.311084371168457 BAMBI other 0.163891690894743 1 0.362089716450021 4.12796497071667 -1.01389334935018 0.178090612282267 3.83954964696854 2.27098380716643 1.69069882174072 0.0914757047828094 10.0415830520986 9.93268991787432 1.01096310618016 0.312490233287435 IL11 other 1 1 1 1.69069882174072 1.01096310618016 0.615885231686937 -4.77837544702721 5.57870595601712 -0.856538323528831 0.392077223735091 -13.5723795435571 20.4283891385325 -0.664388143946042 0.506723429151882 MYO3A other 1 1 1 -0.856538323528831 -0.664388143946042 6.53653755723528e-18 593.522764842157 71.9482929702924 8.24929599215402 1.20219887475572e-15 -524.120565226822 262.659456066993 -1.99543764033815 0.0464924961737589 WAC essential 7.3621022507141e-14 1 1.55396226550924e-11 8.24929599215402 -1.99543764033815 1.64860931210103e-07 59.5640592268138 10.9504517865881 5.43941568691867 8.20176717488735e-08 -13.3702151971053 40.2668179809892 -0.332040520396164 0.739990929687906 CREM other 0.00117479899580319 1 0.00084240350653268 5.43941568691867 -0.332040520396164 9.17411467887842e-17 305.25210379937 38.3905966275378 7.95122062730359 1.07719547927718e-14 -200.617425114406 175.726169965125 -1.14164796941868 0.254103574927314 NUBP2 essential 1.0003454645849e-12 1 1.37051580828436e-10 7.95122062730359 -1.14164796941868 0.830539270802823 2.60900758533787 99.3487792750854 0.0262610935370814 0.979058788762505 -255.730906455684 452.282521581361 -0.565422925390851 0.572020979550596 TPSD1 other 1 1 1 0.0262610935370814 -0.565422925390851 0.0032079756373849 78.1289895624201 26.1779727422377 2.98453170273038 0.00296944148194433 -73.1215649788999 91.8316364015185 -0.796256800425379 0.426234650197643 HIVEP1 other 1 1 1 2.98453170273038 -0.796256800425379 0.834735776489851 -5.56083865837178 15.621180223435 -0.355980699206669 0.721993534096834 27.5413073275548 72.7065505349155 0.37880090755136 0.704984051590647 TREM2 other 1 1 1 -0.355980699206669 0.37880090755136 0.134571316966008 1226.43197476081 649.859099902056 1.88722751585021 0.0596648095793417 -703.118098147355 3270.89534166087 -0.214961967505304 0.829877978295618 CRISP3 other 1 1 1 1.88722751585021 -0.214961967505304 0.315439234304773 172.872677426254 222.214073721325 0.777955574690783 0.436932173347395 1104.44895863731 740.709224481107 1.49106953462206 0.136520725721836 FKBP5 other 1 1 1 0.777955574690783 1.49106953462206 3.94190870626583e-24 709.507307348206 68.3523756067157 10.3801411589636 3.69317695303142e-23 61.6649280539406 227.839912563706 0.270650244551418 0.786762326769434 SRPK1 other 5.02751036397144e-20 1 5.22215221158642e-19 10.3801411589636 0.270650244551418 3.9719290571897e-10 168.597525773851 45.6301121960653 3.69487423238003 0.000242205739955905 -628.779664245856 153.971975925058 -4.08372796717176 5.0968467412224e-05 BRPF3 other 3.32450462086778e-06 0.58761546079553 1 3.69487423238003 -4.08372796717176 7.06974868491377e-53 214.758124256764 12.9249219278252 16.6158159759887 2.30893784419335e-50 -83.3131580922461 68.2869926457739 -1.22004432856514 0.22298160709586 MRPS18A essential 1.07495528754114e-48 1 3.53937082136398e-46 16.6158159759887 -1.22004432856514 0.358548461439933 3.55276384245392 15.5478763763484 0.228504765310485 0.819340357271378 107.232849351175 75.0871095903902 1.42811262726911 0.153837529712615 PGC other 1 1 1 0.228504765310485 1.42811262726911 2.96781408767833e-16 120.799833094464 16.1818719044532 7.46513344115771 3.62376160939542e-13 -123.301798281543 60.9320539723501 -2.02359497576587 0.0435328192762082 TMEM14A other 3.18921301861914e-12 1 4.45251588946416e-09 7.46513344115771 -2.02359497576587 0.0010661790673681 12.1997035234227 15.1481096548302 0.805361447824789 0.420972288503936 -200.107194035805 61.971572395627 -3.22901592295124 0.00131911141977004 EFHC1 other 1 1 1 0.805361447824789 -3.22901592295124 4.49794667314483e-72 11959.3016934495 568.661286247926 21.0306239982644 8.78465726948169e-72 3464.98691684993 3012.51884915493 1.15019592917134 0.250583852640334 HSP90AB1 other 6.96866878070329e-68 1 1.36452081366859e-67 21.0306239982644 1.15019592917134 1.62820789328343e-77 546.220001487543 25.3186578140964 21.5738134895693 1.71916032051023e-74 -146.313477177807 132.376613887649 -1.10528191408481 0.269540836404182 CDC5L essential 2.52958378300513e-73 1 2.67312238236136e-70 21.5738134895693 -1.10528191408481 1.96942899400952e-07 614.604091153127 112.391278188129 5.46843225792268 7.01077970088547e-08 188.128864539649 387.619819746943 0.48534376973414 0.627633449595302 ITPR3 other 0.00139396184195994 1 0.000722601063770265 5.46843225792268 0.48534376973414 7.76322331388036e-18 65.8507646291599 8.37209379609944 7.86550727129214 2.06918662071284e-14 -74.6183873419152 32.1979507101692 -2.31748871266979 0.0208564294783011 ZNF184 other 8.73052093878985e-14 1 2.6142103766086e-10 7.86550727129214 -2.31748871266979 6.10516764036032e-05 3309.77256026499 887.970598510451 3.72734476323547 0.000213916485362601 -2630.07796858596 2703.25795831506 -0.972928965397477 0.33102421512013 DSP other 0.341217819419738 1 1 3.72734476323547 -0.972928965397477 1.72952967779606e-13 48.6101461110295 21.3803797269416 2.27358665897666 0.0233818854646146 -355.391913572507 54.683354910753 -6.49908759534837 1.83674423339068e-10 SIRT1 other 1.68646438881894e-09 2.61295234642158e-06 1 2.27358665897666 -6.49908759534837 3.27172658115105e-13 388.525933324372 50.8322206600061 7.64330041614841 9.65800353145752e-14 115.648930431567 132.806664174467 0.870806680903003 0.384244531785407 HNRNPH3 other 3.15296290625526e-09 1 1.20261459973709e-09 7.64330041614841 0.870806680903003 3.28504441585598e-34 67.1021868617785 11.2509387953055 5.96414113369605 4.52157741490383e-09 -244.578997015373 27.0562835102492 -9.03963757338381 3.02112155493697e-18 IFT74 other 4.66147802609963e-30 4.62412865198653e-14 4.90274639098022e-05 5.96414113369605 -9.03963757338381 8.09923236166878e-10 52.312436177783 16.8255583369705 3.10910551258426 0.00197529349013594 -178.093994239902 41.490149582327 -4.29244039929329 2.09431301990451e-05 JAK2 og 6.66404838718107e-06 0.247903832166097 1 3.10910551258426 -4.29244039929329 0.852966292722109 1.65518145940439 3.03153274583401 0.545988316200434 0.585297384929025 0.0465318359077427 11.1739323560855 0.00416432052968361 0.99667888635928 IL12RB1 other 1 1 1 0.545988316200434 0.00416432052968361 9.71712722755708e-24 297.881727781641 54.8959631950513 5.42629567721099 8.68756789399858e-08 -840.560054343948 121.843212072063 -6.89870235731153 1.46857825726993e-11 ABL1 og 1.23184021863741e-19 2.12752932130695e-07 0.000890736336171674 5.42629567721099 -6.89870235731153 1.28057143282495e-12 311.615571288581 43.3535624064208 7.18777313770252 2.19364416068638e-12 99.5090553956536 70.367165933834 1.41414044569056 0.157894820151295 ACOT7 other 1.20578606114797e-08 1 2.64619295103598e-08 7.18777313770252 1.41414044569056 8.32783980420619e-18 541.658318292987 87.1755711857694 6.21341863236805 1.03289544727356e-09 -634.976026430167 169.54916834693 -3.745084877862 0.000199598269286455 SH3GLB1 other 9.35882637196691e-14 1 1.1497159223602e-05 6.21341863236805 -3.745084877862 1.07998278494086e-15 174.83621080092 21.0859467440923 8.29159880382912 8.99114800283721e-16 53.0766826225827 40.6644995021991 1.30523388391175 0.192371153675309 CDC7 essential 1.14046182089754e-11 1 1.16516286968767e-11 8.29159880382912 1.30523388391175 0.00980955108268164 62.8382098882803 32.8442706221719 1.91321678630491 0.0562478420265407 -84.1295015502389 62.279891396586 -1.35082929118355 0.177314826520995 SYDE2 other 1 1 1 1.91321678630491 -1.35082929118355 0.0171548299996361 -16.0341445210386 14.4211762518078 -1.11184720587744 0.266693173505846 -91.8848030888564 32.1862395650282 -2.85478528497294 0.00447026719819002 PCSK5 other 1 1 1 -1.11184720587744 -2.85478528497294 0.000442092658970476 8482.73860599967 2340.54663112912 3.62425533128876 0.000316883964389456 -211.913180810911 4614.77911203034 -0.0459205469354905 0.963390367399598 SCD essential 1 1 1 3.62425533128876 -0.0459205469354905 1.97951157576699e-22 148.406636318767 16.179951495098 9.17225471063551 9.72087191324185e-19 -129.144308477099 52.9939392774622 -2.43696374034272 0.0151330496721092 TMED1 other 2.45835542594503e-18 1 1.31834464887386e-14 9.17225471063551 -2.43696374034272 0.00299377407148515 282.308840625424 152.263105709113 1.85408565857545 0.0642719563527723 -570.307367850831 296.622937380672 -1.92266779126028 0.0550474440075254 ABLIM1 other 1 1 1 1.85408565857545 -1.92266779126028 1.12015452020452e-10 195.315551708602 120.680526554988 1.61845127200043 0.106144980946935 -1694.5464529 297.268933628574 -5.70038191416691 1.96179257232301e-08 ERMP1 other 9.63668933731946e-07 0.000265548242589643 1 1.61845127200043 -5.70038191416691 8.82637150554148e-06 233.488123657792 83.3149946030184 2.80247420971846 0.00525167932216404 -960.247992988388 300.59269486211 -3.19451540041211 0.0014816429798621 RAB18 other 0.0539291298988585 1 1 2.80247420971846 -3.19451540041211 0.201294166742669 -176.810683554306 99.0158730240025 -1.78568019605751 0.0747121185730651 -195.343219212495 360.097932621821 -0.542472481833564 0.587716859442732 NRP1 other 1 1 1 -1.78568019605751 -0.542472481833564 0.243169926810939 -2.948125352144 5.68740039465807 -0.518360788333638 0.604435874219417 -37.6808517561387 22.461544160947 -1.67757174155698 0.0940556750938169 HSD17B7P2 other 1 1 1 -0.518360788333638 -1.67757174155698 1.3036402347677e-07 77.6427593285041 14.4231061147666 5.3832204180355 1.09279347660424e-07 166.095539340567 54.3336879182281 3.05695316670828 0.0023466598176402 PRTFDC1 other 0.000935622596492781 1 0.00111290087657376 5.3832204180355 3.05695316670828 0.166063304732305 25.3860760035934 87.6187605702206 0.289733338367052 0.772131462586943 -269.562484560386 168.749248365776 -1.59741443100292 0.110758327700557 PALMD other 1 1 1 0.289733338367052 -1.59741443100292 7.52258235601634e-13 270.137533336862 107.657153856937 2.5092390394775 0.0123876161063541 -1753.81369442266 287.199006516676 -6.10661476755777 1.93344934471302e-09 TSPAN15 other 7.1366738811527e-09 2.691554832775e-05 1 2.5092390394775 -6.10661476755777 1.80732755483318e-06 207.48331851911 40.0219937248283 5.18423244842982 3.05946328887706e-07 125.895307559444 105.870203154481 1.1891476903633 0.23489844388662 H2AFY2 other 0.011798234277951 1 0.00304171840180157 5.18423244842982 1.1891476903633 1.26875483506011e-14 154.11875463284 37.3650344395842 4.12467851145797 4.31089402852273e-05 -597.73373859374 106.272621772572 -5.62453178084679 3.01687436639475e-08 WASHC2A other 1.29108492015717e-10 0.000406161795947725 0.368495221558123 4.12467851145797 -5.62453178084679 1.59092126671266e-17 57.181576994381 8.37467481634894 6.82791609803785 2.30924912263398e-11 -125.714773412133 30.8292309146866 -4.07777844864252 5.22632638755832e-05 MAST3 other 1.7722862911179e-13 0.60228185290222 2.71013477032324e-07 6.82791609803785 -4.07777844864252 2.59136854688929e-09 6.05596138606722 19.3890968942135 0.31233849720327 0.754913500789486 -407.778860312656 66.4957297067129 -6.13240672914204 1.75955382991896e-09 MZF1 other 2.07568620605832e-05 2.45176230660907e-05 1 0.31233849720327 -6.13240672914204 3.42352635155607e-06 78.6892813729838 20.0259163571181 3.92937231783724 9.61437401595769e-05 -146.648986315681 70.8659932087124 -2.06938447731586 0.0389816144243875 OCEL1 other 0.0217462393850842 1 0.795721077224272 3.92937231783724 -2.06938447731586 2.56878458728623e-25 494.01322687828 47.1185848394212 10.4844665552215 1.50238560500882e-23 -206.448782640594 174.797675159321 -1.18107281720094 0.238089893584629 MYO9B other 3.33274112354516e-21 1 2.13128421926552e-19 10.4844665552215 -1.18107281720094 8.70967370664876e-19 374.409936406685 42.7857450288669 8.75081025594099 2.65155755143087e-17 -486.325222548888 255.611440635179 -1.90259567936552 0.0576200981629353 KCNK6 other 1.00169957300167e-14 1 3.52895794519935e-13 8.75081025594099 -1.90259567936552 2.08141992287265e-15 28.6164799150741 3.73923883952055 7.65302275228382 8.97390873138451e-14 -47.6161718167964 22.3390343209871 -2.13152328487458 0.0334927663902076 CATSPERG other 2.17674895534022e-11 1 1.11859772336708e-09 7.65302275228382 -2.13152328487458 4.4657505857338e-92 1139.86747628966 46.2847408768229 24.6272843856506 1.39748884313303e-90 -128.75887212679 276.515210544272 -0.465648424451411 0.641653198595307 PSMD8 other 6.96612433868616e-88 1 2.18036209305615e-86 24.6272843856506 -0.465648424451411 1.09030831192157e-14 132.953157658502 17.6069858015224 7.55115947483793 1.93535248037554e-13 -153.661070247897 105.457773280248 -1.45708623905373 0.145692701283157 FBXL19 other 1.11167835483523e-10 1 2.39499869446474e-09 7.55115947483793 -1.45708623905373 1.52055223445324e-13 18.2634557167523 2.53277295775515 7.2108538828287 1.97284422097239e-12 -21.1821226777887 15.0704410240118 -1.40554099538554 0.1604576443559 STX1B other 1.48573158828426e-09 1 2.38339310335674e-08 7.2108538828287 -1.40554099538554 5.406371464822e-15 173.212661094797 26.9116103188719 6.43635438542789 2.77897680985558e-10 -583.135493065495 160.212307215432 -3.63976715147965 0.000300102972484071 HSD3B7 other 5.57883471454982e-11 1 3.15886293976284e-06 6.43635438542789 -3.63976715147965 1.14571533046784e-26 154.90385534202 15.1484956368002 10.2256923100478 1.70421182899828e-22 -256.233595115707 90.7080735847827 -2.8248157522187 0.00491178263715125 SETD1A essential 1.51383366614716e-22 1 2.39475846210838e-18 10.2256923100478 -2.8248157522187 5.17637082473226e-11 207.567337928208 31.9005594270226 6.50669899388597 1.79763505625984e-10 -199.980709210892 190.934769817992 -1.04737711942944 0.295408546034947 BCL7C other 4.52880683455826e-07 1 2.05505639631625e-06 6.50669899388597 -1.04737711942944 2.47827246562187e-33 -113.524828540668 285.886629925048 -0.397097368878115 0.691456123407166 -6015.0019821822 513.111727850352 -11.7225969622282 2.2804632088654e-28 CIRBP other 3.49362069478716e-29 3.56367985649396e-24 1 -0.397097368878115 -11.7225969622282 0.00010743062934023 180.820082360217 92.3042385708289 1.95895752091023 0.0506436566079229 -400.198121435799 165.668423715395 -2.41565720528196 0.0160453156484298 ATP5D other 0.580984843471966 1 1 1.95895752091023 -2.41565720528196 1.93232652684102e-06 -0.956312583985 2.7660538963735 -0.345731724619971 0.729682045862894 -23.3519836612129 4.96453679721752 -4.70375880269455 3.26547548366861e-06 CBARP other 0.0125852426693156 0.0404853650465235 1 -0.345731724619971 -4.70375880269455 3.7436198938429e-10 48.2721868770663 9.11152272601625 5.29792750658835 1.70504051168279e-07 -90.085388060632 41.706384683913 -2.15999034064872 0.0312103334098776 IGFALS other 3.13677910905097e-06 1 0.00171765781146924 5.29792750658835 -2.15999034064872 0.0029436757230691 227.921207723315 87.7360604665666 2.59780535518994 0.00964356293648974 -357.21878962168 268.958776253765 -1.32815442796572 0.184699827865079 HNRNPM essential 1 1 1 2.59780535518994 -1.32815442796572 2.73848838550603e-17 64.3410519492598 17.8927307217108 3.59593250186173 0.000353276107671041 -350.814232597218 51.8939664632023 -6.7602123427196 3.62653384766568e-11 MARCH2 other 3.03451897997923e-13 5.22220874063857e-07 1 3.59593250186173 -6.7602123427196 2.95277555744354e-11 313.231406338119 49.780833522071 6.29220895225154 6.45077361098396e-10 -280.717092520974 187.353630906264 -1.49832747389572 0.134629284535092 NDUFB7 essential 2.61704497656221e-07 1 7.23131721791302e-06 6.29220895225154 -1.49832747389572 7.1735727572824e-07 176.467254318611 70.8436292229202 2.49094034642593 0.0130392414569074 -429.516456223429 139.559234303728 -3.07766417870032 0.00219199212522163 TIMM13 essential 0.00485176356617506 1 1 2.49094034642593 -3.07766417870032 3.71513351331074e-07 206.02450776968 47.018491849884 4.38177618345256 1.42356585161576e-05 -66.7234792187612 84.352854684019 -0.791004400132082 0.42930066459139 CDC34 other 0.00257607357812967 1 0.126683125135286 4.38177618345256 -0.791004400132082 3.87938940075486e-31 367.459850829813 32.2570158700626 11.3916256950119 5.29184818433498e-27 -75.0839486554738 75.7873411794394 -0.990718865274609 0.322281881454859 MTAP other 5.36713523594435e-27 1 7.66630046464608e-23 11.3916256950119 -0.990718865274609 5.85913535836865e-09 70.1341041182058 97.3982951083194 0.720075274831122 0.471799713133993 -889.551779446751 174.642573877227 -5.093556282972 4.91109177009579e-07 MISP other 4.59766351571188e-05 0.00632106621729029 1 0.720075274831122 -5.093556282972 2.83156444944723e-14 297.853559822602 47.3156497234136 6.29503264910707 6.40817200310612e-10 -233.598835056309 99.3903653034104 -2.35031669662545 0.0191196821228915 CEP170B other 2.84345702013491e-10 1 7.1861240842832e-06 6.29503264910707 -2.35031669662545 1.12929167939009e-16 292.562530933514 87.2224318020795 3.35421204028547 0.000853084060210292 -866.132502926717 156.232074443618 -5.54388403284814 4.67942504312641e-08 POLR2E essential 1.22912106384817e-12 0.000626153865020745 1 3.35421204028547 -5.54388403284814 4.83137467384203e-15 93.3607278342186 28.4295847296271 3.28392865116054 0.00109235052269142 -262.68763735787 51.0747932552164 -5.1431953144723 3.82746101969563e-07 POLRMT essential 4.99322572541574e-11 0.00494469689134479 1 3.28392865116054 -5.1431953144723 0.28008571379359 0.901037857015519 8.69687659604225 0.103604765120568 0.917522797495569 -20.9175877023733 15.6025074145931 -1.34065552071515 0.180615458938298 HCN2 other 1 1 1 0.103604765120568 -1.34065552071515 3.76830707096371e-13 4.78989036935022 3.64570597142244 1.31384439856003 0.189473477101986 -40.6905458529262 6.65147251268952 -6.11752446925065 1.86122283306337e-09 IZUMO4 other 3.61945894166064e-09 2.59175279504074e-05 1 1.31384439856003 -6.11752446925065 4.74306154138789e-11 88.3050006036752 51.8843770670063 1.70195742139553 0.0893389183525634 -524.40217947205 106.652853397173 -4.91690716908611 1.16837204603883e-06 RASSF7 other 4.1587163594889e-07 0.0147892533587595 1 1.70195742139553 -4.91690716908611 1.30747452703358e-06 -62.274489867742 79.981148334949 -0.778614600617457 0.43654656158456 -812.844956875239 162.552531877966 -5.00050628239659 7.73416852618687e-07 GADD45B other 0.00864109914916491 0.00987421295738277 1 -0.778614600617457 -5.00050628239659 6.87199047880579e-10 110.217549964999 58.7039568545857 1.87751483665772 0.0610028036016604 -488.778270698668 105.260673305018 -4.64350317503971 4.33611160638203e-06 PALM other 5.67351533930206e-06 0.0534512477718712 1 1.87751483665772 -4.64350317503971 2.70450088021123e-25 -7.94919534057741 185.632270663373 -0.0428222706761615 0.96585955419885 -3340.18250109096 337.114676805334 -9.90814915785982 2.52456971241356e-21 MKNK2 other 3.50773764163396e-21 3.90374214630508e-17 1 -0.0428222706761615 -9.90814915785982 1.75686049534526e-08 18.8073355063093 22.7463568455708 0.82682847341206 0.408699485552223 -220.529132967311 46.391317222616 -4.75367258724444 2.5653355983772e-06 ARVCF other 0.00013397818137503 0.0319846042405669 1 0.82682847341206 -4.75367258724444 1.94667948531037e-21 165.686412849337 23.9088183662514 6.92992896224483 1.21060249920786e-11 -142.298269914693 48.6376371343445 -2.92568221440616 0.00358239931701991 TRMT2A other 2.3714449490051e-17 1 1.43359547956195e-07 6.92992896224483 -2.92568221440616 9.7584973692938e-30 404.651562061448 37.5116531113005 10.7873561546544 1.08680457732099e-24 29.4303962343707 76.3098428533043 0.385669726655666 0.699894018274619 RANBP1 other 1.33232764582968e-25 1 1.55315242144942e-20 10.7873561546544 0.385669726655666 7.85607121431135e-09 88.649740992961 20.2520706943358 4.37731737810667 1.44444852406373e-05 -64.5580196422214 41.1987263678659 -1.56699066533705 0.117705925837888 ZDHHC8 other 6.11987947594854e-05 1 0.128469251730228 4.37731737810667 -1.56699066533705 2.04544645512838e-28 138.852974559202 19.0523952218816 7.28795371616739 1.14672769428269e-12 -175.521396024565 39.1235917257138 -4.48633134848926 8.8884852704503e-06 KLHL22 other 2.756443642931e-24 0.107701776022046 1.39201274808976e-08 7.28795371616739 -4.48633134848926 1.71788194993507e-32 276.437606803465 39.4660063337824 7.00444844774776 7.53734762857127e-12 -474.897995773672 81.409256933902 -5.83346432162195 9.44387481647627e-09 MED15 other 2.40537830629908e-28 0.000129220539113845 8.97095114752553e-08 7.00444844774776 -5.83346432162195 2.73956446557324e-46 241.811609193173 34.3159443257763 7.04662552478666 5.7057097789109e-12 -645.62318528782 71.7213468007439 -9.00182740685962 3.93382379377694e-18 SNAP29 other 4.10277174364248e-42 6.01835702209935e-14 6.81090576308595e-08 7.04662552478666 -9.00182740685962 1.06148220172246e-42 517.02301631415 52.1183442547058 9.92017347649082 2.14072913031082e-21 -560.135212606657 108.928893446319 -5.14220970107159 3.822305473172e-07 CRKL other 1.57216128897114e-38 0.00493841867133822 2.98010902230569e-17 9.92017347649082 -5.14220970107159 8.20552975612353e-24 176.368866009814 29.5845492146911 5.9615194651076 4.57488878075087e-09 -292.795472157645 60.2293056683633 -4.86134563413109 1.54009800804271e-06 LZTR1 other 1.04136378134964e-19 0.0193882938232497 4.95917943833394e-05 5.9615194651076 -4.86134563413109 0.946106755782229 -186.11488521083 689.428799092404 -0.269955194003848 0.78729653738578 68.3739759205985 1567.77419626062 0.0436121324637697 0.965229495814379 MMP11 other 1 1 1 -0.269955194003848 0.0436121324637697 2.1321880006041e-06 70.3448900103836 17.5466238057158 4.00902708060959 6.95303492967089e-05 -20.6042752476327 33.2210605398155 -0.620217263170704 0.535375915175841 CECR2 other 0.013825106995917 1 0.58245573605853 4.00902708060959 -0.620217263170704 1.21249003787421e-39 499.929078361495 42.7965417289395 11.6815298191124 2.66264043264871e-28 -205.006175002719 97.373246885624 -2.10536447699564 0.0357148989904738 SMARCB1 other 1.77290293337968e-35 1 3.88505865527773e-24 11.6815298191124 -2.10536447699564 0.0279074555477764 60.5194566453956 22.5572286621291 2.68292960770489 0.0075188566051903 69.0673793505021 51.3235534189832 1.34572481345292 0.178948794257762 DERL3 other 1 1 1 2.68292960770489 1.34572481345292 0.000135623224294335 -17.9378565383672 11.0093274732023 -1.62933263471629 0.103837917672274 -94.5154949605868 22.400195292416 -4.21940495280355 2.88238076359334e-05 SLC7A4 other 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1.53342770994899 2.71260053363221 9.24922761049257e-39 258.29846838343 39.4761291566737 6.54315592489553 1.38852417678119e-10 -724.363568016775 89.1924440533405 -8.12135574604927 3.0863319216054e-15 CABIN1 other 1.34687252463993e-34 4.64462090882397e-11 1.59263723076803e-06 6.54315592489553 -8.12135574604927 4.56631674164578e-27 74.009296808705 17.3445800791815 4.26699847853552 2.33842010724328e-05 -284.393336720718 37.3386073763593 -7.61660267224587 1.16743932456584e-13 TBC1D10A other 6.06452526457976e-23 1.7323849794186e-09 0.204518222579497 4.26699847853552 -7.61660267224587 0.0289482095535666 -12.4634042382534 205.86809145114 -0.0605407285335009 0.951747172054763 -1071.77987271803 452.424916576994 -2.36896738762096 0.0181854707632547 SUSD2 other 1 1 1 -0.0605407285335009 -2.36896738762096 2.03935002360795e-31 344.046826222682 59.1554977476925 5.81597382022032 1.03002472628628e-08 -930.412801106508 127.388110057979 -7.3037648543733 1.00309308927454e-12 SF3A1 essential 2.82796667773714e-27 1.47384467607108e-08 0.000110192045218106 5.81597382022032 -7.3037648543733 0.00896111961726952 -97.8402741232915 46.7503539916262 -2.09282424130556 0.036826669493431 -306.390741776365 102.349558988665 -2.993571685153 0.00288240114763909 GGT5 other 1 1 1 -2.09282424130556 -2.993571685153 5.17377333478257e-19 37.9880433818416 12.3386724279906 3.07877882353572 0.00218375321240215 -174.928245994875 26.5799155773522 -6.58121902177617 1.10249899489317e-10 RNF215 other 5.984503616343e-15 1.57458906450642e-06 1 3.07877882353572 -6.58121902177617 2.00148989079821e-08 -493.11933274507 183.682036861768 -2.68463558641923 0.00748314095866043 -2394.51265346239 395.687061258418 -6.05153134360026 2.67880332684019e-09 SEC14L2 other 0.000152173276397388 3.71710749632345e-05 1 -2.68463558641923 -6.05153134360026 6.30749496401432e-35 327.060000269079 54.1645640816439 6.038265161261 2.8808941437329e-09 -917.480364191401 120.067671201611 -7.64136053451742 9.71434743172498e-14 SPECC1L other 8.99259557019521e-31 1.44306631098275e-09 3.14680067319945e-05 6.038265161261 -7.64136053451742 8.54508796901633e-47 242.141132388083 26.5593753150712 9.1169739316376 1.58457539825e-18 -425.085712614574 58.1038661434352 -7.31596261710378 9.49044753473102e-13 PPIL2 other 1.28159229359307e-42 1.39481107417942e-08 2.14329668367296e-14 9.1169739316376 -7.31596261710378 6.93117003736695e-18 82.9347155253988 13.7004008726966 6.0534517417427 2.67901033894016e-09 -95.5994568741352 29.9309990851691 -3.19399484802046 0.0014862816453408 YPEL1 other 7.80311122806771e-14 1 2.92976570666496e-05 6.0534517417427 -3.19399484802046 1.5142287157976e-62 900.973318158731 56.6924437909153 15.8922998888806 5.06144801076276e-47 -243.478232815921 125.213690618957 -1.94450168837257 0.0523481342517132 SNRPD3 essential 2.33251791381462e-58 1 7.72883111243473e-43 15.8922998888806 -1.94450168837257 2.75315716665038e-38 612.403861989994 54.7541587773067 11.1846090902562 2.84236259304429e-26 -313.179677691887 118.525829815683 -2.64229053008029 0.00847273345485103 PES1 essential 4.00116331029299e-34 1 4.1012449855036e-22 11.1846090902562 -2.64229053008029 1.02560564261107e-37 698.047722206606 76.0957974484393 9.17327560276355 1.00505141453888e-18 -839.710234239844 166.245007352558 -5.05104031460661 6.0482428835569e-07 MAPK1 other 1.4862051367077e-33 0.00775626667387336 1.36284971811473e-14 9.17327560276355 -5.05104031460661 0.000171456756643303 52.3375456295007 24.3292356962641 2.15122029655611 0.0319075575556637 -112.890437892133 53.0737310442648 -2.12704921381879 0.0338745881394684 PPM1F other 0.902376910213702 1 1 2.15122029655611 -2.12704921381879 1.31539261670453e-31 45.4015723569259 4.55049725890405 9.97727715758706 1.23072245762357e-21 -23.3526918402686 9.86360295719931 -2.36756202998051 0.018255893296224 SLC35E4 other 1.82681726607925e-27 1 1.71722704512217e-17 9.97727715758706 -2.36756202998051 1.39458523175357e-24 54.2510731163747 7.54379315891971 7.19148470451218 2.17655124324656e-12 -63.9238092627441 16.4576959612036 -3.88412870267103 0.000115584885641787 TOP3B other 1.79162364723381e-20 1 2.62579141985265e-08 7.19148470451218 -3.88412870267103 0.618632034602499 -10.8867138105459 14.2964751550772 -0.761496361337687 0.446690029437043 -26.3244830943631 29.2300311790878 -0.900597160949885 0.368200325009531 CYTH4 other 1 1 1 -0.761496361337687 -0.900597160949885 9.02361543354222e-10 70.3059561689117 11.584386069747 6.06902737405462 2.41666837175761e-09 18.5890169207275 24.8977164871383 0.746615334395433 0.455618923053376 CRYBB2P1 other 7.40116937859133e-06 1 2.64721853442329e-05 6.06902737405462 0.746615334395433 0.0118631236549711 -26.3217355345745 8.94401137841771 -2.9429452200933 0.00338950892005559 -33.7395420523305 18.370409179902 -1.83662441712202 0.0668097884717515 MFNG other 1 1 1 -2.9429452200933 -1.83662441712202 2.3985120878771e-13 44.6703057070115 24.3596540781167 1.83378243236798 0.0672324192379223 -294.737407483 50.0654092598318 -5.88704680218148 6.88371920105814e-09 CARD10 other 2.32583717161442e-09 9.45547669457346e-05 1 1.83378243236798 -5.88704680218148 1.95651149407758e-09 11.5305882230664 5.13568462117742 2.24519009121376 0.0251575355825536 -46.3654649988482 11.0748552512375 -4.18655268597458 3.30389574319069e-05 LRP5L other 1.58007868261705e-05 0.385300321570899 1 2.24519009121376 -4.18655268597458 6.84794829097817e-23 598.867751616629 75.7568069960563 7.90513453989427 1.52467040444574e-14 -268.092655844983 148.712401476909 -1.80275923986481 0.0719855068597852 SLC25A1 other 8.56678331201369e-19 1 1.93251973763498e-10 7.90513453989427 -1.80275923986481 5.94076715095298e-06 -24.5515892644575 35.8860105713399 -0.684154880232506 0.494169241836169 -355.297776514686 76.8308739465707 -4.62441409636659 4.70053878642498e-06 GRK3 other 0.0367852301987009 0.0578299566463559 1 -0.684154880232506 -4.62441409636659 7.66215351739998e-05 0.407608304847116 6.31697330920392 0.0645258868283052 0.948575374539682 -50.1426921370918 13.0441806638524 -3.84406605744473 0.000135419620261646 PLA2G3 other 0.423027495695653 1 1 0.0645258868283052 -3.84406605744473 0.582935760552239 -2.63639810020548 3.24684068025905 -0.81198874839622 0.417153246031394 -6.36256058967121 6.67851303914571 -0.952691198231917 0.341169656181723 LGALS2 other 1 1 1 -0.81198874839622 -0.952691198231917 4.89105820555189e-40 261.226909359743 30.5758261604655 8.54357648387959 1.3135188181337e-16 -411.948999411748 62.8922308805829 -6.55007770663978 1.33405285431159e-10 GGA1 other 7.16491116531297e-36 1.9022259649629e-06 1.72767130149125e-12 8.54357648387959 -6.55007770663978 3.13033589963541e-24 170.573089187283 25.8050689904785 6.6100613507455 9.28062750402209e-11 -198.366618625207 50.5674441359734 -3.92281282976868 9.88780072023107e-05 HIRA other 3.99837804460431e-20 1 1.07033477003887e-06 6.6100613507455 -3.92281282976868 1.08490479143318e-18 204.360448725825 24.8107571615333 8.23676792269227 1.32405722076547e-15 -13.3536632086584 51.0339069674209 -0.261662569106911 0.793680640958891 SH3BP1 other 1.24514522912786e-14 1 1.71015230634068e-11 8.23676792269227 -0.261662569106911 0.236231624366759 -24.0338647190799 109.963453202932 -0.218562295190264 0.827072994963851 -373.693223311688 234.468183279767 -1.59379075695655 0.111563720230292 SEZ6L other 1 1 1 -0.218562295190264 -1.59379075695655 0.0279131580724265 698.238114793467 315.849955969602 2.21066396115207 0.0274744215377351 -205.201563737336 649.680183626468 -0.315850119657207 0.752237414483319 LGALS1 other 1 1 1 2.21066396115207 -0.315850119657207 3.02145115002862e-43 147.694392727502 19.0865485450797 7.73814041751285 4.94961901280798e-14 -325.113158866328 40.3123969823579 -8.06484315503761 4.71564316607192e-15 HPS4 other 4.48564637733249e-39 7.0814813424902e-11 6.20929705156761e-10 7.73814041751285 -8.06484315503761 1.11382862723701e-12 -6.99209130238929 32.6320735341545 -0.21427051808617 0.83041669426126 -458.688205814987 67.1589068023563 -6.82989386895281 2.28799587217282e-11 PIK3IP1 other 1.05056316120995e-08 3.30546763652807e-07 1 -0.21427051808617 -6.82989386895281 1.71567789400441e-23 61.0894966255891 7.83575753545629 7.79624641895351 3.26680105374121e-14 -46.9922275896025 16.1175782939722 -2.91558860348004 0.00369652138124651 NOL12 essential 2.16672961233817e-19 1 4.11551596750318e-10 7.79624641895351 -2.91558860348004 5.95522025673625e-69 197.082672007889 15.0347899668331 13.108441983071 2.65034960117929e-34 -251.547934017279 31.6844211453091 -7.93916773368355 1.1752308554693e-14 SRRD other 9.20915260501693e-65 1.759203067552e-10 3.95326146511903e-30 13.108441983071 -7.93916773368355 3.59073130824533e-30 247.328531837267 58.2401742595209 4.2466997220022 2.55303583017277e-05 -1006.46234112704 120.076915356423 -8.38181375778654 4.50913600589532e-16 PATZ1 other 4.9193018922961e-26 6.82142094971843e-12 0.222497072599557 4.2466997220022 -8.38181375778654 1.51423373291381e-26 324.100818030311 43.0780661484867 7.52356934763879 2.22004618632342e-13 -372.26124571239 88.63818305965 -4.19978425620336 3.12148189115009e-05 TRIOBP other 1.99772856383319e-22 0.364713944161976 2.74308906782122e-09 7.52356934763879 -4.19978425620336 4.16067610632541e-71 242.686752658527 20.2079983743961 12.0094404285985 1.24715751324597e-29 -411.520391614521 42.5864765926594 -9.66317067154258 1.72289675569869e-20 TFIP11 essential 6.44322301825554e-67 2.65722366631408e-16 1.83020365068846e-25 12.0094404285985 -9.66317067154258 6.35886627916021e-22 146.246367782694 19.8563942869215 7.36520264804673 6.60839629928105e-13 -121.660557539503 40.8503623865745 -2.97820020268624 0.00302898216097597 GCAT other 7.8233131832508e-18 1 8.06158264549295e-09 7.36520264804673 -2.97820020268624 0.198918620372537 6.8746279515085 20.7252755691051 0.331702607696875 0.740240881392041 -68.5091659479255 48.4588765848841 -1.41375885650011 0.158001570747023 GGTLC2 other 1 1 1 0.331702607696875 -1.41375885650011 0.17085774555439 -1.01563236666679 0.55843624278809 -1.81870782884016 0.0695067303342528 -1.5121035603481 1.17712420713118 -1.28457434753917 0.19948880660334 CRYBB1 other 1 1 1 -1.81870782884016 -1.28457434753917 3.42722237332184e-28 632.615289494489 179.598816882861 3.52238004945822 0.000463698173994524 -3117.35445700016 369.486858885412 -8.43698329733273 2.96336415872588e-16 EIF3L essential 4.60892864764321e-24 4.48682967272686e-12 1 3.52238004945822 -8.43698329733273 3.30436853795e-31 541.896193957875 64.1769189128659 8.44378638204206 2.81474815552865e-16 -493.012927787354 120.623851442588 -4.08719272259356 5.02613339361906e-05 SNU13 other 4.57390693023038e-27 0.579764486953959 3.68140911261592e-12 8.44378638204206 -4.08719272259356 1.4200090799954e-11 328.512737290488 49.6585037288774 6.61543769188219 8.8910579779498e-11 51.3662616200888 102.161945597335 0.502792515547286 0.615314016178695 MICALL1 other 1.27729816745586e-07 1 1.02576135891607e-06 6.61543769188219 0.502792515547286 2.56836617142038e-14 198.716525537165 27.2436172090188 7.29405805450022 1.07355526998209e-12 10.7110642230316 56.0655316360247 0.191045441119999 0.84856153330401 POLR2F essential 2.58300585859748e-10 1 1.30361816433926e-08 7.29405805450022 0.191045441119999 0.000317927980498736 518.575044327027 134.34109809073 3.86013700719342 0.000126986843312299 202.80808665124 276.46494322827 0.733576142721962 0.463524287407042 SOX10 other 1 1 1 3.86013700719342 0.733576142721962 1.50858962449066e-27 27.1209047633155 2.97236239656691 9.12436006949903 1.39863560851258e-18 -11.3285664821799 5.58306130698707 -2.02909584173874 0.0429349443721304 CCDC134 other 2.01441972558238e-23 1 1.89319315968263e-14 9.12436006949903 -2.02909584173874 5.52089055939106e-40 54.1807514918682 8.01554379033993 6.75946048191578 3.58287953175132e-11 -139.426621469922 16.6780580959705 -8.35988342693253 5.29775750801094e-16 DEPDC5 other 8.08700049139603e-36 8.01126890361414e-12 4.18014554969427e-07 6.75946048191578 -8.35988342693253 3.17612794518347e-26 124.040178948233 16.854841758618 7.35932029055156 6.92591940484265e-13 -150.441630527864 34.7084296707613 -4.33444070950284 1.74338390057661e-05 PICK1 other 4.17279689438204e-22 0.207375514973587 8.44338834644367e-09 7.35932029055156 -4.33444070950284 7.65975545925293e-05 -4.42126668653059 22.2953671382804 -0.198304278153797 0.842882053797903 -187.105580114398 47.1490829985513 -3.96838216599349 8.21937540529349e-05 TTC28 other 0.422971696459947 0.932159364714335 1 -0.198304278153797 -3.96838216599349 0.00715441142305544 4.64677931696038 1.48961409740149 3.11945175939615 0.00190859693367455 5.77119160282606 3.05947888315025 1.88633156927811 0.0597866102988975 SLC16A8 other 1 1 1 3.11945175939615 1.88633156927811 4.61263963179205e-16 92.1509641322058 12.8149654170253 7.19088668080049 2.13507055489873e-12 -17.5498602435082 24.2674606164134 -0.723184865565961 0.469876564121998 CENPM other 4.9262991267539e-12 1 2.57703015976276e-08 7.19088668080049 -0.723184865565961 1.61674355821624e-14 419.36973403243 51.1536159728932 8.19824221721995 1.75594855080739e-15 357.482978778065 97.1634675678584 3.67919124055963 0.000257207531588481 SEPT3 other 1.63856959625216e-10 1 2.26499803568645e-11 8.19824221721995 3.67919124055963 4.17908248404128e-06 128.408704101165 43.4296217234366 2.95670786448203 0.00324414638953504 -202.993120922266 90.2564225534529 -2.24907120379214 0.0249064621888788 SLC5A1 other 0.0262864288246196 1 1 2.95670786448203 -2.24907120379214 0.00697517306182762 -1.98545390182265 37.6855087921442 -0.0526848108320227 0.958002930182366 -198.762486707466 73.2788121067568 -2.71241414800634 0.0068969797662057 TPTEP1 other 1 1 1 -0.0526848108320227 -2.71241414800634 4.0905974914477e-08 248.830794258954 50.8321921997024 4.89514190695106 1.29728417565881e-06 -70.5340570455505 105.618245498412 -0.66782076063374 0.504531747756299 KDELR3 other 0.000304381359338623 1 0.0124046312876495 4.89514190695106 -0.66782076063374 0.0448194041926731 3.6128261545051 2.11671089057399 1.70681134140403 0.0884256971886496 -3.24152565146921 4.11992676137718 -0.786792057047553 0.431744967394042 CYP2D6 other 1 1 1 1.70681134140403 -0.786792057047553 6.56438647664567e-17 170.681402062743 297.068973842124 0.574551424388905 0.56583265968763 -4703.03613552702 617.244750845164 -7.61940239927091 1.1418387938656e-13 DDX17 other 7.18865963057467e-13 1.69460295397593e-09 1 0.574551424388905 -7.61940239927091 3.02860484487011e-09 11.2898310026436 2.36902314207385 4.76560604332488 2.42055288912656e-06 -7.50290486564996 4.92231511141556 -1.52426341991996 0.128025099753357 DMC1 other 2.41591808475288e-05 1 0.0227749821337918 4.76560604332488 -1.52426341991996 3.63241486872318e-31 462.105843254314 48.147025527465 9.59780668051259 2.91397509331423e-20 -247.355869747343 93.9807929748352 -2.63198321611924 0.00872893060724815 TCF20 other 5.02653569533914e-27 1 4.01808025617099e-16 9.59780668051259 -2.63198321611924 1.7105814586498e-27 40.2298625779957 8.43647747704189 4.76856160494387 2.39107118690811e-06 -114.934915632103 16.2801213001878 -7.05983165068779 5.15843672849054e-12 HSCB essential 2.28362624729748e-23 7.51945321912066e-08 0.0225095441535529 4.76856160494387 -7.05983165068779 1.15771950190939e-23 58.4214081375249 17.7252728879736 3.29593843247192 0.00104487844684103 -278.151567049621 36.8054158517157 -7.5573542809639 1.75587887285976e-13 CBY1 other 1.46590443331767e-19 2.60028102281802e-09 1 3.29593843247192 -7.5573542809639 4.17672569252747e-40 362.323965079887 38.0468054533934 9.52311135618802 5.50180819643747e-20 -337.480635818479 70.2751008841669 -4.8022789234375 2.0316550831146e-06 TOMM22 essential 6.11973848469125e-36 0.0254342899855117 7.56388590846223e-16 9.52311135618802 -4.8022789234375 4.95147227041007e-09 7.46708607998935 1.70565064266744 4.37785200157501 1.43722747909952e-05 -7.47312213565319 3.90109834331488 -1.91564566642097 0.0559331538550297 RSPH14 other 3.90324559076426e-05 1 0.127855756540693 4.37785200157501 -1.91564566642097 6.12369787580314e-17 -4157.12097282353 2125.34659010858 -1.95597320087504 0.0509834825611783 -35129.0044127465 4095.96240653994 -8.57649580881327 1.03774066130016e-16 XBP1 other 6.71402235103056e-13 1.57591296825042e-12 1 -1.95597320087504 -8.57649580881327 5.27896372578943e-63 459.419383696572 37.4357639992651 12.27220536238 9.56747838144505e-31 -571.27966316714 75.495862930863 -7.56703269542467 1.63333408342546e-13 RTCB essential 8.13699468693183e-59 2.41962111118648e-09 1.41062901256026e-26 12.27220536238 -7.56703269542467 1.39526269267071e-28 423.016006790728 46.1734377961735 9.16145790699136 1.04404956531089e-18 -177.524431856013 85.2855571085929 -2.08152983781268 0.0378532929430925 JOSD1 other 1.88332558256692e-24 1 1.41562680560503e-14 9.16145790699136 -2.08152983781268 3.28721992411374e-43 418.435527701713 43.1522255473132 9.69673110470119 1.27839209005304e-20 -515.55409295894 86.9537433785885 -5.92906150933911 5.40623401672135e-09 FBXO7 other 4.87922053336202e-39 7.44546548782864e-05 1.76839977817037e-16 9.69673110470119 -5.92906150933911 1.22249018078237e-42 409.598163523338 40.6460183711655 10.077202637243 5.16861123379468e-22 -454.953361857317 84.3989042268701 -5.39051266156692 1.04852877459399e-07 GTPBP1 other 1.81001896166638e-38 0.00138646959864563 7.2324376994489e-18 10.077202637243 -5.39051266156692 2.5726291722055e-42 547.437136609144 57.048022409673 9.59607561289138 2.9387765091348e-20 -647.211698253995 112.877512888141 -5.73375229214491 1.6258367983589e-08 POLDIP3 other 3.80491854569193e-38 0.000220837412321089 4.05169117314414e-16 9.59607561289138 -5.73375229214491 9.50197873753177e-09 45.2479817782073 21.6739648759264 2.08766517973206 0.0372918473209225 -202.914415850448 49.1946644615588 -4.12472405435364 4.29157285785832e-05 RAB36 other 7.35738213647085e-05 0.497221631311465 1 2.08766517973206 -4.12472405435364 0.182251763550949 -1338.52120649101 1335.98637123315 -1.00189735113504 0.316837792289148 -4668.82347852105 2531.41286412573 -1.84435480465709 0.0656739653953596 TIMP3 other 1 1 1 -1.00189735113504 -1.84435480465709 6.59278221344003e-33 327.950417845371 34.5543246173703 9.49086464507286 7.88462952141683e-20 -314.434833874102 73.97895317152 -4.25032824058871 2.5247990418153e-05 PPP6R2 other 9.26351828810459e-29 0.296891119327061 1.08216540181446e-15 9.49086464507286 -4.25032824058871 6.44425422962797e-26 453.36424146709 42.7623317026003 10.6019532475476 6.17046178558409e-24 54.4904719151365 91.481393750615 0.595645405924636 0.551667846682634 SBF1 other 8.44132861538968e-22 1 8.78056712088616e-20 10.6019532475476 0.595645405924636 1.59809703345577e-19 1116.11152188073 141.387721163829 7.89397772800561 1.62289151027396e-14 -371.955812846989 293.678823270824 -1.26653944164023 0.205862040919715 SUN2 other 1.87392858143024e-15 1 2.05555438691299e-10 7.89397772800561 -1.26653944164023 1.95420491252913e-12 702.754391250217 128.926283176067 5.45082332273945 7.59648585266453e-08 -502.717057235353 255.098732193021 -1.97067642364828 0.0492647015622065 CYB5R3 other 1.82620449075848e-08 1 0.000781602429380653 5.45082332273945 -1.97067642364828 5.75552104619195e-43 177.06921992531 17.6315112291817 10.0427704479605 6.94123863063066e-22 -201.100959864167 36.6227097208289 -5.4911545704056 6.13611407246907e-08 DNAL4 other 8.53371105518881e-39 0.000817944005860127 9.70176923403248e-18 10.0427704479605 -5.4911545704056 7.28410572408338e-32 509.062980038183 46.970440867832 10.8379434093585 7.74566308697699e-25 -182.869120689658 100.565226994259 -1.81841304549631 0.0695706961551157 LMF2 other 1.01380183467792e-27 1 1.10824947448467e-20 10.8379434093585 -1.81841304549631 5.50046650220509e-17 93.6351362356995 20.5959644384953 4.54628558499008 6.75005584512158e-06 -182.857282578402 39.5577023456942 -4.62254559125844 4.75109250627468e-06 RHBDD3 other 6.03786207947052e-13 0.058428935642166 0.0616010096425796 4.54628558499008 -4.62254559125844 1.50261107905235e-44 761.320804340819 73.3445915227097 10.3800537781316 3.66735505897555e-23 -766.286022495486 145.488952237971 -5.26697052049766 1.99718748800943e-07 PACSIN2 other 2.24009259665124e-40 0.0026065293906011 5.18600678889732e-19 10.3800537781316 -5.26697052049766 3.07492755273727e-28 38.5873192436042 8.2443678493653 4.68044608739467 3.61640395599145e-06 -120.765406982416 16.4163708857104 -7.3564009867453 6.98506349678472e-13 TTLL1 other 4.13639254394217e-24 1.02771239228194e-08 0.0336036255590726 4.68044608739467 -7.3564009867453 0.37549205751081 0.0526880250930104 2.9884927925511 0.0176303002049517 0.985940332708135 -6.96186789970589 5.69168919647999 -1.22316374970219 0.221804341793082 RASL10A other 1 1 1 0.0176303002049517 -1.22316374970219 6.36144587428851e-38 641.128886778277 79.2968668641343 8.08517299777776 4.13022590285482e-15 -1004.12160249148 155.304316549664 -6.46550994073871 2.2678359949295e-10 AP1B1 other 9.22791338524291e-34 3.22146103079735e-06 5.28916729119589e-11 8.08517299777776 -6.46550994073871 8.8512735363773e-29 149.809794684932 22.1287400953393 6.76991975320299 3.34638711312098e-11 -264.610432959341 45.5834124627688 -5.80497199887057 1.09473382372739e-08 HMGXB4 other 1.19748879673649e-24 0.00014938737758584 3.908245509414e-07 6.76991975320299 -5.80497199887057 1.63379031475792e-26 277.351392688164 40.2616183221371 6.88872937170704 1.56083037812334e-11 -420.428336108342 82.9356730880078 -5.06933048776491 5.48119675560488e-07 TOM1 other 2.15464266710275e-22 0.00704169347192559 1.84162376314773e-07 6.88872937170704 -5.06933048776491 4.78477408337071e-07 154.138964277219 28.9755935713024 5.31961369136124 1.52690690102093e-07 80.4971945701881 59.4427705561206 1.35419654597341 0.176241134474214 NEFH other 0.00328139806637563 1 0.00154156520727074 5.31961369136124 1.35419654597341 2.2737810500737e-10 87.5632838829681 18.5409888465961 4.72268683226374 2.99385161138789e-06 -100.66915276219 39.7395009385158 -2.5332263965253 0.011592854968466 CHKB other 1.93112224582759e-06 1 0.0279775433084198 4.72268683226374 -2.5332263965253 0.0142732891726657 -4.61277963168967 20.0875568273415 -0.229633681753231 0.818462587327777 -106.602519693747 39.9987954310903 -2.66514325106117 0.0079237124287361 BIK other 1 1 1 -0.229633681753231 -2.66514325106117 0.576883673206583 76.4799199297547 75.0106428860857 1.01958758100368 0.308377310370723 106.103697743319 154.515849480923 0.686684881193491 0.492573921688445 HMOX1 other 1 1 1 1.01958758100368 0.686684881193491 1.57925848107983e-25 72.5425463137557 12.7232527811709 5.70157235428911 1.94550273295727e-08 -145.835401669442 25.3184955843025 -5.76003424784291 1.40553141156278e-08 MCAT other 2.05556283897351e-21 0.000191349046370157 0.000205873099201538 5.70157235428911 -5.76003424784291 2.70323236238672e-46 248.566491059611 20.3268095746104 12.2285049282937 1.60905223283946e-30 -144.441385790877 41.6999870842407 -3.46382327407158 0.000574912817902069 THOC5 essential 4.04890143238283e-42 1 2.37029484419581e-26 12.2285049282937 -3.46382327407158 3.61240541633295e-17 407.37633656188 51.3865112005717 7.927690108632 1.27294803450282e-14 -20.7285453510401 105.852051449224 -0.195825636511007 0.844819768129143 MCM5 essential 3.98809557963158e-13 1 1.61664400381859e-10 7.927690108632 -0.195825636511007 0.556406265599075 -1.07878462100128 1.04129679685419 -1.03600109427047 0.300661081725457 -1.64805805620326 2.15941664448489 -0.76319595869207 0.445676764887504 APOBEC3H other 1 1 1 -1.03600109427047 -0.76319595869207 1.67192061551462e-16 285.496925703544 41.9181922603646 6.81081197228758 2.67423017682322e-11 -209.089285153185 89.8446169432581 -2.32723219561653 0.0203337165655791 ARSA other 1.80851652980217e-12 1 3.1328606521484e-07 6.81081197228758 -2.32723219561653 3.42634676178307e-07 596.583253161343 123.623442880503 4.82581005075237 1.81205617470379e-06 -9.11370906620821 246.003097361888 -0.0370471313733148 0.970460966772982 TSPO other 0.00238233890346777 1 0.017165608142969 4.82581005075237 -0.0370471313733148 1.21779469549033e-07 283.447127758519 49.7528103683901 5.69710787510818 1.99591711899835e-08 212.67845413368 100.536076581576 2.11544414070218 0.0348451583234475 RASD2 other 0.000875716165527098 1 0.000211088194505265 5.69710787510818 2.11544414070218 1.38770587356809e-05 394.34690044839 196.848971662415 2.00329672600308 0.04564006790039 -1109.72835518859 392.220160031405 -2.82935062567854 0.00483612243358229 TTLL12 other 0.0833594918252353 1 1 2.00329672600308 -2.82935062567854 7.17292070694124e-07 -39.987020277719 38.9675492590046 -1.02616205119645 0.305270434467406 -416.920955723398 80.8099810917426 -5.15927550150114 3.47702625539862e-07 CBX7 other 0.00485176356617506 0.00449996737973689 1 -1.02616205119645 -5.15927550150114 3.44357274539164e-05 146.689230688722 48.9265139939602 2.99815414412786 0.00283988223032824 -168.69466836784 101.3334313902 -1.66474840586671 0.0965366521437592 PDGFB other 0.198487533044374 1 1 2.99815414412786 -1.66474840586671 1.3377071211166e-10 35.8227848544722 6.70803373483152 5.34028096317735 1.36951425765416e-07 -19.157457392193 13.9667566153148 -1.37164682680777 0.170743035273239 CABP7 other 1.14668254422115e-06 1 0.0013867701373006 5.34028096317735 -1.37164682680777 7.78540968583109e-17 -1660.03641685279 938.139908121297 -1.76949770762567 0.0773679536766862 -16574.6049815653 1936.83268619273 -8.55758223192022 1.16648906927432e-16 RPL3 essential 8.51178840951913e-13 1.7710803538792e-12 1 -1.76949770762567 -8.55758223192022 2.6919348555709e-24 85.1973146093243 11.8027408072563 7.21843476872298 1.7941430796546e-12 -97.3963874915198 24.5849058662437 -3.96163353325057 8.44257039669989e-05 ZMAT5 essential 3.44298468027518e-20 0.956627651650065 2.1707337120741e-08 7.21843476872298 -3.96163353325057 7.20568267205719e-10 236.355910093878 58.4267087858776 4.04534013647895 5.97801303126608e-05 -334.562763839369 120.622261394534 -2.77364028804826 0.00573288877681096 RBFOX2 other 5.94540877271438e-06 1 0.504185619056981 4.04534013647895 -2.77364028804826 2.06977577036487e-17 175.689020803128 38.1749124995847 4.60221148653684 5.20141865382705e-06 -377.845424311215 78.8138503454256 -4.79415004666303 2.10842720208998e-06 SYNGR1 other 2.29848599299019e-13 0.0263764242981457 0.0478374473592474 4.60221148653684 -4.79415004666303 5.86546901420193e-45 132.894885633137 16.4431198880773 8.08209673940882 4.10389753102633e-15 -277.417840422777 33.9475719842164 -8.1719493974933 2.11874557134784e-15 TAB1 other 8.7577317851049e-41 3.19210207779266e-11 5.25586156798541e-11 8.08209673940882 -8.1719493974933 1.24190264886964e-57 370.127893837149 27.6158336937922 13.4027419900182 1.4480168178765e-35 -282.134475365073 57.5233060580572 -4.90469854219296 1.24012197722142e-06 ASCC2 other 1.90222228727362e-53 0.0156813424019648 2.16695716795218e-31 13.4027419900182 -4.90469854219296 7.0911884172039e-42 192.690251131627 35.3018048258065 5.45836826424142 7.32940809642122e-08 -727.170793478496 73.5961725409049 -9.88055177834599 2.81476363998979e-21 MTMR3 other 1.04694305791598e-37 4.35134311106022e-17 0.000754929033931385 5.45836826424142 -9.88055177834599 1.57905482026769e-48 287.007738541122 24.3007242719514 11.8106660249792 8.05558176324274e-29 -234.16146103671 50.26650009156 -4.65839994052076 4.00941751707382e-06 MIEF1 other 2.37805655932315e-44 0.0494802215782081 1.17772605378609e-24 11.8106660249792 -4.65839994052076 0.105678311047928 2.57910967125848 20.4034956749064 0.126405284288145 0.899457653052787 -76.6915631436829 42.1106602622369 -1.82119118214009 0.0691249117459343 APOL4 other 1 1 1 0.126405284288145 -1.82119118214009 0.00157492613574411 259.777493252099 99.248609843009 2.61744213508898 0.00910525903350736 -202.893472689389 205.03984361526 -0.989531932486748 0.322842065592248 APOL1 other 1 1 1 2.61744213508898 -0.989531932486748 1.46771024997387e-08 53.3372140504093 10.159569328442 5.24994833207056 2.18109018289491e-07 -3.40431826675479 20.2085459730257 -0.168459337514874 0.866284200161686 PNPLA3 other 0.000112367896738 1 0.00218610669031557 5.24994833207056 -0.168459337514874 1.50311725412734e-23 6820.36403335628 881.031814843638 7.74133682626062 4.82561029618204e-14 -5520.0892676441 1830.62250144524 -3.01541648443965 0.00268607919457081 MYH9 other 1.90054145611861e-19 1 6.05517579964922e-10 7.74133682626062 -3.01541648443965 0.0448930967685588 7.44432016467895 7.8500330119721 0.948317052084444 0.343389143655325 -21.8571752986301 14.4338664931104 -1.51429800941161 0.130531043500875 CACNA1I other 1 1 1 0.948317052084444 -1.51429800941161 3.50245329186299e-37 232.067567041341 28.6934876542643 8.08781315947322 3.93551614147961e-15 -346.057266176702 57.0746303944526 -6.0632414749783 2.48857126782716e-09 SAMM50 essential 5.05999427075446e-33 3.45513234825124e-05 5.04336393530612e-11 8.08781315947322 -6.0632414749783 8.85346688592284e-41 282.764408712528 37.6320573522183 7.51392372906926 2.35619248619576e-13 -599.369299447119 76.7686373187865 -7.80747607852152 2.99027104551201e-14 TXN2 other 1.30075135487978e-36 4.45909218306751e-10 2.90989772045177e-09 7.51392372906926 -7.80747607852152 1.04604632693205e-28 411.597089864716 50.3399987888067 8.17634286388255 2.05105976018934e-15 -414.969112117165 102.692581313741 -4.0408869541352 6.08783806374026e-05 FOXRED2 other 1.41394082011406e-24 0.697605363723997 2.64155986514785e-11 8.17634286388255 -4.0408869541352 0.633879850848891 -4.67104769159985 4.90439296269533 -0.952421171616876 0.341306403199555 -3.75741577737408 8.98814369422555 -0.418041355946282 0.67608184307952 GRAP2 other 1 1 1 -0.952421171616876 -0.418041355946282 1.61532270776233e-44 709.826304629064 95.5427000678729 7.42941432600092 4.22022619818876e-13 -1705.79018044591 195.066626145582 -8.74465414279964 2.75803452922323e-17 EIF3D essential 2.40780002819053e-40 4.20296881908328e-13 5.17188720588033e-09 7.42941432600092 -8.74465414279964 1.83673883734068e-24 107.185038511844 26.6557083104264 4.02109136488107 6.61297622739206e-05 -342.234553906615 49.3681970164616 -6.93228788145733 1.1791128176292e-11 TNRC6B other 2.35469918947075e-20 1.71089269837997e-07 0.555688392387755 4.02109136488107 -6.93228788145733 4.88768180888777e-17 238.388467892789 52.1851521346679 4.56812825375327 6.11201968794494e-06 -439.263150091586 98.0452048322277 -4.48021043806519 9.12074485045819e-06 SGSM3 other 5.37742752613833e-13 0.110388374925095 0.0559555402431359 4.56812825375327 -4.48021043806519 1.2928474061596e-20 114.637739948987 17.6444764619178 6.4970893410417 1.84364731015187e-10 -133.990348126348 36.0241911845319 -3.71945472529807 0.000220260399657292 IFT27 other 1.54921904680105e-16 1 2.10636705184851e-06 6.4970893410417 -3.71945472529807 0.155027138300668 -10.8236550098655 76.5700665083473 -0.141356217950856 0.887640582656495 -277.614098597785 156.33077699202 -1.77581218451921 0.0763197490431203 PVALB other 1 1 1 -0.141356217950856 -1.77581218451921 5.33515270294976e-17 171.86101679279 58.8063973040656 2.92248844805373 0.00361631842750001 -685.952718601127 116.062485722643 -5.91020185661337 6.02125626016461e-09 KIAA0930 other 5.85853118310914e-13 8.2816358602304e-05 1 2.92248844805373 -5.91020185661337 0.561055572290313 -4.87734178683894 6.64510611272127 -0.73397500417666 0.463278454406153 -14.0639240352227 13.5671111332115 -1.03661891593083 0.300371527157759 NCF4 other 1 1 1 -0.73397500417666 -1.03661891593083 0.880702888998593 -13.4252644533838 26.6634839567082 -0.5035075114408 0.614810572480992 -11.5244860359865 54.4446253239695 -0.211673530075939 0.832440727375808 CSF2RB other 1 1 1 -0.5035075114408 -0.211673530075939 3.107551976223e-39 127.204192579045 20.1155110490966 6.32368684387751 5.33756722680384e-10 -313.234823181303 37.5818683638261 -8.33473259362495 6.39770425189907e-16 SLC25A17 other 4.53547210929747e-35 9.67076974717063e-12 6.00369561670895e-06 6.32368684387751 -8.33473259362495 0.0413629063203937 12.022671906888 6.71808422129891 1.78959827100284 0.0740726038062092 -8.87615328230982 13.2645069651927 -0.669165714609797 0.503672616111921 UPK3A other 1 1 1 1.78959827100284 -0.669165714609797 2.21597420246677e-07 61.6903780286516 17.1900510171454 3.58872570925599 0.000362196034546195 -66.9937641033166 33.9408593190957 -1.97383818345533 0.0489038283115905 FAM118A other 0.00156292660499981 1 1 3.58872570925599 -1.97383818345533 7.77845048648207e-05 35.2968823512408 10.0493720742889 3.51234704918004 0.000481014581224357 -14.355534987598 20.5465652110338 -0.698682959421796 0.48504821540661 KCTD17 other 0.428981544329486 1 1 3.51234704918004 -0.698682959421796 1.45059026442981e-47 708.055988093927 83.2280549939291 8.5074196212512 1.74366936374546e-16 -1246.80393755197 155.595864354061 -8.01309175361399 6.89878425539642e-15 ST13 other 2.1805272854909e-43 1.03516257752223e-10 2.28839167297954e-12 8.5074196212512 -8.01309175361399 0.384994530919625 -13.5886639710357 84.2888885676534 -0.161215365417103 0.871983522678339 -222.530858248102 172.333866506122 -1.29127758089381 0.197154847989831 IL2RB other 1 1 1 -0.161215365417103 -1.29127758089381 1.22960176376227e-21 235.363001986663 35.3029851704192 6.6669433434733 6.43548812095094e-11 -240.712710403127 66.2195170915782 -3.63507196934453 0.000304332082179621 RBX1 essential 1.50367999690488e-17 1 7.451008146437e-07 6.6669433434733 -3.63507196934453 7.04489692953912e-57 151.997190937833 19.2989418698432 7.87593392233315 1.84222843522204e-14 -382.683203114794 36.3032624126995 -10.541289616465 9.02926175816617e-24 L3MBTL2 other 1.07801012815808e-52 1.4032375698366e-19 2.33152430761701e-10 7.87593392233315 -10.541289616465 2.37621651319182e-10 21.9956127583984 8.2128688883967 2.67818871301772 0.0076255163155812 -64.4248804515408 15.4492373948471 -4.17010100919473 3.54172249132326e-05 CHADL other 2.0155068464893e-06 0.412256497990028 1 2.67818871301772 -4.17010100919473 1.20989815886513e-24 785.459403050737 101.408649127425 7.74548729136274 4.67296606980351e-14 -600.586832684422 190.759930001292 -3.14839092612559 0.00173159510848385 RANGAP1 essential 1.55532408322113e-20 1 5.86644160403132e-10 7.74548729136274 -3.14839092612559 5.36264215907871e-35 354.954947139797 72.6370635105727 4.88669186204274 1.35040684002612e-06 -1185.72438527268 136.637666214892 -8.67787351847675 4.66528725167366e-17 ZC3H7B other 7.64980903992577e-31 7.10150025449764e-13 0.0128990861359295 4.88669186204274 -8.67787351847675 9.94977741218696e-30 139.327256079023 16.0193697667601 8.69742431241739 4.01099344034534e-17 -101.031793910896 30.0544838387877 -3.36162132921101 0.000829204625013582 PHF5A essential 1.35824411453764e-25 1 5.32419269271441e-13 8.69742431241739 -3.36162132921101 2.08102601300129e-37 690.02861155567 92.0081082427947 7.49965002796052 2.61345627630887e-13 -1164.42758115782 172.619537627402 -6.74563028706071 3.89949601327335e-11 ACO2 essential 3.01103653821156e-33 5.61215466230301e-07 3.22422100808226e-09 7.49965002796052 -6.74563028706071 6.25624345830884e-40 449.027957368989 60.7454969082398 7.39195463405751 5.48030012175179e-13 -846.19150127077 113.966690430985 -7.4249019434604 4.37327636052547e-13 POLR3H essential 9.16226854469329e-36 6.44970797650297e-09 6.70131098887808e-09 7.39195463405751 -7.4249019434604 2.70915699687748e-25 163.848676224964 17.1739679930599 9.54052530499512 4.84988305515171e-20 -13.3904707789013 33.0516569492325 -0.405137654655835 0.685536777955229 TRMU other 3.51350570925041e-21 1 6.67440906049979e-16 9.54052530499512 -0.405137654655835 3.36530246054949e-20 115.140359027615 19.616076835638 5.86969351682141 7.58919251025703e-09 -149.918694468523 36.8023881601391 -4.07361320727825 5.31656451443463e-05 PMM1 other 3.99932544411701e-16 0.612308735127436 8.16445330253451e-05 5.86969351682141 -4.07361320727825 1.91921356208417e-33 254.628218867317 26.7285369559522 9.52645553652773 5.35210853414605e-20 -164.535487786686 50.2376730710604 -3.27514149697883 0.00112342792841276 DESI1 other 2.70705072931972e-29 1 7.35914923445082e-16 9.52645553652773 -3.27514149697883 9.70710364207573e-11 159.643361196633 38.6763134319658 4.12767782217549 4.24408959940303e-05 -205.596579190906 74.2184116100263 -2.77015601292027 0.0057958410887385 CERK other 8.3694647601977e-07 1 0.362869660748959 4.12767782217549 -2.77015601292027 5.55193400876808e-36 181.825146901043 20.3079692806827 8.95338890796919 5.60224231075644e-18 -245.84965037179 42.7306057818014 -5.75347917198253 1.46861119689142e-08 BRD1 other 7.97257723659097e-32 0.000199745808889203 7.5305341141188e-14 8.95338890796919 -5.75347917198253 2.97172687741096e-26 257.410988993702 27.6957255105088 9.29424971720024 3.63400729848846e-19 -130.099561070921 58.974110168588 -2.206045342592 0.0278011449764074 ZBED4 other 3.90603780766897e-22 1 4.95060814273083e-15 9.29424971720024 -2.206045342592 2.72263556306369e-07 239.330100486645 44.695097629216 5.35472821811674 1.27227126772736e-07 347.701738421703 96.0484045256401 3.62006782037576 0.000322406513617709 MLC1 other 0.00190530036703197 1 0.00129084642823618 5.35472821811674 3.62006782037576 4.90516790828789e-11 68.9951679303289 19.3805138330187 3.56002779517544 0.000404033529129093 -166.643366791825 41.3121721834277 -4.03375949470586 6.29313083374312e-05 HDAC10 other 4.29568504940693e-07 0.720256589457518 1 3.56002779517544 -4.03375949470586 5.34514809034929e-36 228.119535723382 22.0304415691079 10.3547418696892 4.6833274940455e-23 -392.637160745895 70.4907007981547 -5.57005613932233 4.00822559202806e-08 ABHD4 other 7.67616717255062e-32 0.000537462969635043 6.61520008533927e-19 10.3547418696892 -5.57005613932233 5.20727588167248e-36 463.733361836132 55.5529959286825 8.34758511370766 5.96036636651666e-16 -1170.1206681961 150.697829846555 -7.76468161079397 4.18166571865902e-14 KHNYN other 7.47973107643434e-32 6.22691842165514e-10 7.75324456956487e-12 8.34758511370766 -7.76468161079397 6.62108869109761e-31 439.334799382718 47.2558492771414 9.29694008473216 3.86223259227729e-19 -556.912663015125 107.032929300575 -5.20318995896278 2.81416190641399e-07 FKBP3 other 9.13511606710737e-27 0.00365362640309728 5.25958834416322e-15 9.29694008473216 -5.20318995896278 8.27883696320609e-40 297.331092106073 28.9567416262192 10.268112895577 1.03415734112451e-22 -527.180647702256 78.8567562231494 -6.68529461458491 5.76954496019509e-11 SDR39U1 other 1.21177336630448e-35 8.27987397237597e-07 1.45619695203742e-18 10.268112895577 -6.68529461458491 0.000217555184958307 -13.0957056635303 5.84958954910531 -2.2387392403512 0.0255809734621966 -58.9772989070646 14.6701515442191 -4.02022424439814 6.64466370740328e-05 CTSG other 1 0.758887042022529 1 -2.2387392403512 -4.02022424439814 0.123174953836558 -1.61652880533202 2.9612081396339 -0.545901783699635 0.585359732917704 12.5634460167021 7.4263966382135 1.69172838844282 0.0912768451860259 GZMH other 1 1 1 -0.545901783699635 1.69172838844282 1.53455925229008e-10 6.10347208307981 6.69596899463323 0.911514388428574 0.362432641506801 113.055027181618 16.7927816237443 6.73235856421564 4.29156149874853e-11 GZMB other 1.31281544033416e-06 6.17083627905051e-07 1 0.911514388428574 6.73235856421564 7.84969964547409e-50 410.010007768232 29.0789942194952 14.0998689525978 1.077452032133e-38 -447.667808264497 95.9255540865824 -4.66682535771888 3.85780223440525e-06 RBM23 other 1.18663909540632e-45 0.0476438575949048 1.62479766445657e-34 14.0998689525978 -4.66682535771888 1.18607890166918e-68 564.248756789842 29.325915167256 19.2406188714566 2.71376241039711e-63 -152.034384284658 98.0771075085767 -1.55015159140336 0.121687746535349 PRMT5 essential 1.83379658987072e-64 1 4.19981870633057e-59 19.2406188714566 -1.55015159140336 0.00200299608438551 42.9318783494557 15.9449900582354 2.69249953701174 0.00731667637308241 188.164683452891 67.3799192714499 2.79259288950528 0.00541802062920928 COCH other 1 1 1 2.69249953701174 2.79259288950528 2.71375987600833e-46 29.2055058653308 2.57896333465397 11.3245137970329 9.15413273328282e-27 -96.8196471259639 10.8157040497382 -8.95176556983435 5.95375803634994e-18 AP4S1 other 4.06439816629767e-42 9.10091453436451e-14 1.32451146517869e-22 11.3245137970329 -8.95176556983435 4.14692060157831e-07 34.05020096796 6.2200410835633 5.4742726793138 6.78471135933254e-08 16.6338263892873 15.437505001255 1.07749447776277 0.281748669857649 POLE2 other 0.00286303398332967 1 0.000699978670942338 5.4742726793138 1.07749447776277 1.61646747055024e-20 24.4169887193948 3.35699587271702 7.27346402711918 1.24468040650915e-12 -38.009279053466 8.45915332437061 -4.49327226921898 8.59136871912503e-06 VCPKMT other 1.93361838827219e-16 0.10417893708811 1.51017073721756e-08 7.27346402711918 -4.49327226921898 6.26489230824333e-11 74.8607112503318 30.4397956576828 2.45930400099245 0.0142337144671779 -430.073220561662 76.7005330527585 -5.6071738154132 3.28846437195036e-08 SOS2 other 5.45985364663406e-07 0.000441969611590128 1 2.45930400099245 -5.6071738154132 0.582474115149991 -1.04443211272483 2.44480079359212 -0.427205404817566 0.669399070205693 -6.18758631238115 6.00613266939089 -1.03021139441608 0.303369436152934 CDKL1 other 1 1 1 -0.427205404817566 -1.03021139441608 7.05301888111237e-07 134.279102275814 43.1866877676699 3.10927068540637 0.00197420908111174 -333.080451181005 102.234337331647 -3.25800958733166 0.00119236219653933 NIN other 0.00477489378251307 1 1 3.10927068540637 -3.25800958733166 0.000308615634770835 256.056564587602 120.562202906796 2.1238543956065 0.0341345562379384 -778.44680424191 293.74305040694 -2.65009437044887 0.00828198193957036 PYGL other 1 1 1 2.1238543956065 -2.65009437044887 0.510708692394823 -17.7861909941162 19.7676675389015 -0.899761742710115 0.368645900986315 -47.5616198826326 48.7190437619419 -0.976242885944872 0.329378828437519 TRIM9 other 1 1 1 -0.899761742710115 -0.976242885944872 2.19173903656206e-46 231.743878986844 19.0467847118541 12.1670865971732 2.78828222917365e-30 -280.396068617191 45.2017860085036 -6.20320773529703 1.09880679846888e-09 PSMC6 essential 3.28322507676996e-42 1.53810975649673e-05 4.10295730022903e-26 12.1670865971732 -6.20320773529703 5.78844294750367e-15 361.652037413706 56.7536842755835 6.3723094285404 3.98278595126265e-10 -428.533778225272 134.687713996289 -3.18168424951572 0.00154807003148953 GNPNAT1 other 5.96788467887628e-11 1 4.50333607509268e-06 6.3723094285404 -3.18168424951572 4.34521141553407e-11 61.6038745021948 12.3468331764662 4.9894473847444 8.18730764215812e-07 -89.6007184767352 29.0039648626753 -3.089257586022 0.00211024804067002 DDHD1 other 3.81683370740513e-07 1 0.00792367633608063 4.9894473847444 -3.089257586022 3.57429950648858e-10 80.0512222251138 13.0072202280411 6.15436817564897 1.46863097332426e-09 137.022308151701 29.6175791034945 4.62638447500709 4.66151712446483e-06 CDKN3 other 2.99919471589457e-06 0.0573553066994153 1.62313095171798e-05 6.15436817564897 4.62638447500709 2.84684231769348e-19 166.92269612164 43.2168863715015 3.86244151618738 0.00012585256998514 -686.207077992131 98.2748969648988 -6.98252655749134 8.53198770509612e-12 CNIH1 other 3.31771003703998e-15 1.23978313342752e-07 1 3.86244151618738 -6.98252655749134 4.44190358762289e-40 23.4572129309233 6.2945475273529 3.72659239270023 0.000214539584374621 -171.824525385974 14.1713415978283 -12.1247889058228 4.30187100531005e-30 CGRRF1 other 6.50783294622629e-36 6.73113756200863e-26 1 3.72659239270023 -12.1247889058228 6.05589874747864e-35 195.169562139487 31.8496139567766 6.12784702522151 1.72477197978929e-09 -497.34305453592 61.3716409467392 -8.10379267791673 3.61571955332315e-15 ATP6V1D essential 8.63631720377929e-31 5.43731906428736e-11 1.9006987217278e-05 6.12784702522151 -8.10379267791673 0.0116229614446168 19.4384424750919 10.5306709804708 1.84588831149893 0.0654586346588702 -26.3722474042999 20.2917548457189 -1.29965336191038 0.194277429339766 PLEK2 other 1 1 1 1.84588831149893 -1.29965336191038 3.22815611230206e-33 32.1625275798766 12.0637273190776 2.6660522680262 0.00790601536711073 -239.397038871017 23.2196181397934 -10.3101195476054 7.29509577884137e-23 PIGH other 4.54556662173252e-29 1.13212591391839e-18 1 2.6660522680262 -10.3101195476054 1.16212109402114e-23 512.306730932257 50.4789523347646 10.1489176624499 2.77055783510862e-22 26.9334928185176 106.644642951299 0.252553640512607 0.800708379849916 PSMA3 essential 1.47136151714017e-19 1 3.88626147530686e-18 10.1489176624499 0.252553640512607 6.78844303398053e-45 313.582801278818 39.8016134983981 7.87864545469843 1.84969660492146e-14 -660.839590089331 76.3119907478446 -8.65970843655388 5.54841349694534e-17 VTI1B other 1.01324300725193e-40 8.44080145290295e-13 2.34023614454663e-10 7.87864545469843 -8.65970843655388 7.93471578120277e-34 103.648992576882 12.4335819845048 8.33621338613866 6.25971010196433e-16 -174.197805732437 26.3947967862593 -6.59970247708524 9.7654861579859e-11 TIMM9 essential 1.12244489440894e-29 1.39656217545356e-06 8.13824910356383e-12 8.33621338613866 -6.59970247708524 2.04262557301024e-30 142.815849598153 27.7036126600318 5.15513450721158 3.55108785676151e-07 -470.345967060321 58.1196097048596 -8.09272411581582 3.82060128595303e-15 GSTZ1 other 2.80452491174306e-26 5.74274579291599e-11 0.00351593208697957 5.15513450721158 -8.09272411581582 1.22165003351409e-15 44.319596042028 15.3424858471339 2.888684173061 0.00402183216271909 -209.650879675582 32.5364175481504 -6.44357601341084 2.56179179336327e-10 KIAA0586 other 1.28810779533725e-11 3.63518255478248e-06 1 2.888684173061 -6.44357601341084 8.62651737861131e-13 64.4249925905676 35.053056964674 1.837927934659 0.0666181345294227 -437.039535485916 73.5600841996136 -5.94125931530964 5.0518542630996e-09 TMED8 other 8.16758665406919e-09 6.96347591625649e-05 1 1.837927934659 -5.94125931530964 1.29029896845743e-15 3.98656094494012 5.53468926093441 0.720286317260579 0.471658096627753 -86.0230340705027 11.6147418601275 -7.40636641833712 4.97720634225266e-13 SAMD15 other 1.35920093337305e-11 7.33640214848041e-09 1 0.720286317260579 -7.40636641833712 8.37779219257432e-36 800.06414758859 60.5135351051259 13.2212429202606 8.24227934273016e-35 293.758329984507 126.951783701671 2.31393621593235 0.0210422655750942 AHSA1 other 1.20229695755634e-31 1 1.23090199704332e-30 13.2212429202606 2.31393621593235 4.62050095761552e-22 280.179090324109 43.3385681756808 6.46489033021008 2.25721122322142e-10 -482.293746323784 92.9052938568691 -5.19124073884111 2.9553570066117e-07 DAAM1 other 5.70077408150603e-18 0.0038336891089767 2.57164074661616e-06 6.46489033021008 -5.19124073884111 5.44731676421688e-23 236.546535837407 147.362947426236 1.60519682843487 0.109031886551232 -2729.24983958513 309.33940185736 -8.82283285995238 1.52597325518814e-17 SPTLC2 other 6.82548790556375e-19 2.32848259009159e-13 1 1.60519682843487 -8.82283285995238 0.00292689565456434 8.42570030540899 17.3469391971857 0.485716829328365 0.627362448027864 117.043843333006 35.3702487967606 3.30910432679018 0.000997543823594467 RIN3 other 1 1 1 0.485716829328365 3.30910432679018 0.000341770678931047 403.310958589211 100.431680771471 4.0157742605835 6.753054427624e-05 279.545041980016 204.779269448299 1.36510420577798 0.172781480423042 LGMN other 1 1 0.566918919199035 4.0157742605835 1.36510420577798 2.80386438610512e-48 35.6234317139883 6.83500979068854 5.21190646464308 2.65996129662963e-07 -170.483150014593 14.3478254016271 -11.8821595079669 4.19209654521702e-29 ALKBH1 other 4.21981590108821e-44 6.5560197870649e-25 0.00265224740886941 5.21190646464308 -11.8821595079669 3.1863458288312e-43 206.412054189924 27.9498248093772 7.38509295130437 5.76983265585217e-13 -530.46857120082 58.6713433706163 -9.04135717244356 2.72551340737146e-18 SNW1 essential 4.73013038289991e-39 4.17221592400423e-14 7.05188947198253e-09 7.38509295130437 -9.04135717244356 0.789306611304265 284.318580746356 455.079311500575 0.624767097868822 0.532384441927153 -8.36281249656747 929.017785089609 -0.00900177868582014 0.992820998770674 CHGA other 1 1 1 0.624767097868822 -0.00900177868582014 9.12487308089704e-22 225.395862964562 83.9231109966505 2.68574246459426 0.00745668739765277 -1364.61292684435 170.859979337743 -7.98673236490849 8.22791225562975e-15 ITPK1 other 1.11916568337202e-17 1.23352860536401e-10 1 2.68574246459426 -7.98673236490849 2.44026025552421e-19 209.120214262635 72.2736583372022 2.89344996605758 0.00396278229588388 -1161.58125799796 154.90757421625 -7.49854397936924 2.63351912609069e-13 DHRS7 other 2.84997995242672e-15 3.89181456453682e-09 1 2.89344996605758 -7.49854397936924 2.75444762498245e-26 220.791307316592 57.2466759922676 3.85684065475547 0.000128585234328585 -1086.4574955256 125.254582132213 -8.67399401307963 4.8071527724792e-17 PPM1A other 3.62182318208943e-22 7.31648651971335e-13 1 3.85684065475547 -8.67399401307963 0.000835805329891241 76.9281984472076 35.8457879543671 2.14608752763755 0.0323077128544961 -164.392364274151 77.113990806703 -2.13180983832394 0.033469901226416 SIX4 other 1 1 1 2.14608752763755 -2.13180983832394 2.96601102297617e-08 -36.4263232891988 49.9274242301438 -0.729585470327674 0.465962906640801 -549.516666356827 97.8183561488381 -5.61772542487522 3.11491373696884e-08 GALNT16 other 0.000223103349148268 0.000419142792446528 1 -0.729585470327674 -5.61772542487522 0.789971028599657 11.4041304221147 19.3117428111916 0.590528288078987 0.555080865098477 -3.06152224876846 38.9694625838108 -0.0785620854325128 0.937409728485348 ASB2 other 1 1 1 0.590528288078987 -0.0785620854325128 5.47625253628904e-06 27.1975309674255 5.47445759038006 4.96807775353271 9.07434234630636e-07 20.927439155096 11.3615365747315 1.84195500471648 0.0660268470916623 CEP128 other 0.0340677670282541 1 0.00875401806148174 4.96807775353271 1.84195500471648 2.50382276290887e-26 543.591997282757 68.9328462284777 7.88581970750232 1.76747210787832e-14 -516.949869187224 135.053986996174 -3.82772756795301 0.000144619846304675 ERH essential 3.29503075598808e-22 1 2.23779643578475e-10 7.88581970750232 -3.82772756795301 1.01436054082452e-05 832.443437685204 172.075238227844 4.83767127832169 1.71797713673605e-06 768.469412759991 357.627255818489 2.14879990341123 0.0320958142724171 HIF1A other 0.061673120882131 1 0.0162967311190782 4.83767127832169 2.14879990341123 4.67509319046144e-22 -149.083075129571 87.4237981324394 -1.70529167474197 0.088718357081821 -1693.41981042105 170.958836982883 -9.90542425479066 2.34309225892419e-21 SUSD6 other 5.76719495975324e-18 3.62359217842626e-17 1 -1.70529167474197 -9.90542425479066 1.60621590371982e-22 -129.543477060446 137.473053906673 -0.942319046381193 0.346452257950337 -2622.81496296154 268.745289395708 -9.75948255263977 7.95137015539701e-21 SRSF5 other 1.99781134104671e-18 1.22785057939641e-16 1 -0.942319046381193 -9.75948255263977 2.45802090235189e-17 488.286235665239 111.623588477496 4.37440009164086 1.46080046886799e-05 -1293.34066946022 232.982825670116 -5.55122750245756 4.4460882768524e-08 EIF5 essential 2.72619098279848e-13 0.000595420142036073 0.129865161682364 4.37440009164086 -5.55122750245756 9.56864171588478e-14 48.1990620360471 77.8671643736791 0.618990847088552 0.536180556606712 -1130.67398236204 161.177543924821 -7.0150838313396 6.82970369517927e-12 DICER1 other 9.4174571767738e-10 9.93995075796392e-08 1 0.618990847088552 -7.0150838313396 8.96279820450757e-30 163.719186984747 30.921537377539 5.29466517093909 1.73539547358097e-07 -518.161026218044 64.1153395736688 -8.08170134734568 4.18194101287241e-15 ZFYVE21 other 1.22422860675369e-25 6.28211178953694e-11 0.00174789032099076 5.29466517093909 -8.08170134734568 9.52361611814458e-12 370.097208183936 57.961269979027 6.38525015614486 3.68677363766678e-10 -67.7256571916527 114.702646410118 -0.590445463215383 0.555138594221064 MTHFD1 other 8.63982454238076e-08 1 4.1745337899301e-06 6.38525015614486 -0.590445463215383 0.0127057281525967 -4.43534631025135 3.36217476740098 -1.319189696281 0.187659667522281 13.4353534907131 6.95540304317071 1.93164269666656 0.0539217203093968 TCL1A og 1 1 1 -1.319189696281 1.93164269666656 1.10635214833639e-23 108.731808515697 38.3288933561062 2.83681053625761 0.00472682214230394 -642.242410986603 77.286485548365 -8.30989281540942 7.70481182140942e-16 ZC3H14 other 1.4014162662977e-19 1.16404296997854e-11 1 2.83681053625761 -8.30989281540942 9.85567282448581e-20 294.954748602055 33.7567706882144 8.7376470731258 2.97462122419066e-17 -182.393383737133 153.106565622516 -1.19128388123357 0.234063568377508 TELO2 essential 1.16129392890916e-15 1 3.95475891756148e-13 8.7376470731258 -1.19128388123357 2.24069016504969e-06 62.9778240075429 49.0931242280648 1.28282371508841 0.200101136847371 -377.016835084748 95.9333368376243 -3.92998771347735 9.59258556227424e-05 PCNX1 other 0.0144995060580365 1 1 1.28282371508841 -3.92998771347735 0.07838747087637 3.82164119364098 1.88033810157625 2.03242235555264 0.042596134260804 -0.465379799309962 3.89904412533524 -0.119357407700522 0.905036267280317 BDKRB1 other 1 1 1 2.03242235555264 -0.119357407700522 1.66020201200539e-26 127.125779194631 16.6184277309274 7.64968751875646 9.23469759377262e-14 -171.279307975614 34.484574614864 -4.9668383585566 9.12996272558871e-07 GSKIP other 2.18930839323151e-22 0.0116206165571293 1.15055097320813e-09 7.64968751875646 -4.9668383585566 2.85211736169924e-14 101.527429365081 12.6178564436195 8.0463294077514 5.3813686564199e-15 110.258700536297 26.1642196153856 4.21410239468639 2.93579847840469e-05 VRK1 essential 2.86352583114604e-10 0.343752643836405 6.87792727977027e-11 8.0463294077514 4.21410239468639 3.76988704101447e-29 101.537980034946 10.708956837507 9.48159391952354 7.78901274363449e-20 -70.4806628329977 21.8054191253154 -3.23225444225338 0.00130281994800281 PSMC1 other 5.11912961299355e-25 1 1.06911988919127e-15 9.48159391952354 -3.23225444225338 8.56538409040651e-05 0.986064431956007 19.5871983945513 0.0503422905151309 0.959868135876302 -149.817439400387 38.3662008120575 -3.90493288961006 0.000106123692234497 PAPLN other 0.469640009676989 1 1 0.0503422905151309 -3.90493288961006 2.30200691938151e-16 18.040888594099 18.3689321477717 0.982141392268548 0.326468394284649 -284.132705291518 37.368238535003 -7.60358840637804 1.27862115449456e-13 RPS6KA5 other 2.48317486393684e-12 1.89645089634633e-09 1 0.982141392268548 -7.60358840637804 6.1112060687667e-27 319.206812731014 42.7528435435238 7.46632940113215 3.28148540449752e-13 -451.064465479108 87.088640854723 -5.17937197150145 3.13641252839355e-07 PPP4R3A other 8.10345924718464e-23 0.00406510427805088 4.03688334461284e-09 7.46632940113215 -5.17937197150145 2.47213284932033e-26 22.5202730800909 3.93005601809706 5.73026770519044 1.666572344629e-08 -105.436738238218 13.2436575793117 -7.96130054003536 1.00755442096236e-14 C14orf93 other 3.25382125627541e-22 1.50911501171742e-10 0.000176823325765137 5.73026770519044 -7.96130054003536 4.99733699553958e-79 1279.79616354986 57.3147026373368 22.3292820979613 9.15642732505277e-79 505.187031182496 193.141342640836 2.615633837246 0.00915483756845894 PSMB5 essential 7.77085902806405e-75 1 1.42547260596421e-74 22.3292820979613 2.615633837246 1.10307827219626e-31 396.085257835874 49.9817009502562 7.92460541169005 1.31727231696508e-14 -1241.08169391701 168.128782531348 -7.38173247454286 5.94481968084324e-13 ACIN1 essential 1.53305818269837e-27 8.75374698004167e-09 1.67240893361886e-10 7.92460541169005 -7.38173247454286 0.000237183624923489 106.136669578273 26.0840514943667 4.06902545799663 5.41515011911725e-05 142.581860083034 72.8668722843313 1.95674461676727 0.0508849000917619 CCNB1IP1 other 1 1 0.45881276568807 4.06902545799663 1.95674461676727 4.96119157399904e-17 108.612658585168 50.257251901687 2.16113405479542 0.0311190354310068 -730.639061726346 102.539392508931 -7.1254475362989 3.29596589512762e-12 TRIP11 other 5.45483013561194e-13 4.81507657619194e-08 1 2.16113405479542 -7.1254475362989 2.92678339450179e-35 665.090549001106 67.3771991846986 9.87115162175142 2.96821859127321e-21 -1037.38935532659 187.629881149247 -5.52891335309977 5.00409189476045e-08 APEX1 other 4.18500757579811e-31 0.000668846922653682 4.12701112930627e-17 9.87115162175142 -5.52891335309977 1.37268322013452e-20 486.682558900871 51.6442252373314 9.42375564091275 1.25887191841351e-19 -75.958804386406 171.53916716652 -0.442807352053131 0.65808208003751 PABPN1 essential 1.64337635114505e-16 1 1.72415097945914e-15 9.42375564091275 -0.442807352053131 3.87371538567106e-32 602.636649323387 47.1009098495322 12.7945861608313 6.32474565413357e-33 345.753301249655 155.316809692963 2.22611642573109 0.0264182829184121 EFS other 5.40693193531967e-28 1 9.39161482182293e-29 12.7945861608313 2.22611642573109 6.94803424970714e-60 718.848492164364 38.9274968210003 18.4663425822069 5.11386421225215e-59 -54.4993589572142 163.584870740531 -0.333156475354362 0.739149428766438 ARHGAP5 other 1.06742650178251e-55 1 7.89785188940221e-55 18.4663425822069 -0.333156475354362 3.66923190173691e-34 116.153323552992 17.7780875799539 6.53351059446703 1.48707191313569e-10 -308.087719361734 37.2082855438073 -8.28008371949862 9.7274454647298e-16 CINP essential 5.20333775985311e-30 1.46874699071955e-11 1.70388699807087e-06 6.53351059446703 -8.28008371949862 0.0374833224850985 393.119764037022 633.616578613048 0.620437938820255 0.535230285824841 -4769.13204729897 2128.15472822828 -2.24097053848587 0.0254321102508338 DHRS2 other 1 1 1 0.620437938820255 -2.24097053848587 3.06754762259104e-38 741.566886355201 53.4933110355629 13.8627965253861 1.80148497995598e-37 36.3499769743432 139.936476418806 0.259760556393845 0.795150118150089 SRP54 essential 4.45714669562478e-34 1 2.70745177637585e-33 13.8627965253861 0.259760556393845 7.27314938509772e-25 315.594706357021 50.4565810100056 6.25477787118471 8.0424681070484e-10 -925.854092355529 141.122033917097 -6.56066290044705 1.24549454784596e-10 CHD8 other 9.38672659640712e-21 1.77745367232506e-06 8.98584961600517e-06 6.25477787118471 -6.56066290044705 4.71368131474912e-16 279.388161876224 43.0109859536563 6.49573953448219 1.88047252638525e-10 -521.755606587875 134.797373031007 -3.87066598447625 0.000121843150547394 PCK2 other 5.03232617162616e-12 1 2.14749962513196e-06 6.49573953448219 -3.87066598447625 1.99745839983934e-46 587.958041484785 38.6851144756834 15.1985602072953 1.63958820891262e-43 -110.024666338402 101.198794854675 -1.08721320739442 0.277440536939209 KIAA0391 other 2.99279192047928e-42 1 2.49299387165164e-39 15.1985602072953 -1.08721320739442 4.39594407944827e-43 429.333110028465 42.0469641448553 10.2107992517457 1.72386080317476e-22 -1096.99629957203 130.800685234611 -8.38677792554681 4.42519723779939e-16 DCAF11 other 6.5213830418615e-39 6.69576594051425e-12 2.42219681454086e-18 10.2107992517457 -8.38677792554681 6.7148842247403e-45 836.416772919079 54.0542954318359 15.4736412016289 8.24408873306126e-45 172.306555047346 141.403665194332 1.21854376837081 0.223561573536737 PSMA6 essential 1.00233076822698e-40 1 1.25491518694658e-40 15.4736412016289 1.21854376837081 0.00219480143820031 163.85129208757 82.8755003476906 1.97707756092161 0.0485526199058572 -496.271950330215 216.798672711506 -2.28909127589819 0.0224679611673897 NFKBIA other 1 1 1 1.97707756092161 -2.28909127589819 2.59493705255921e-23 90.6872080948447 9.70913016284771 9.34040501814078 2.65633173881574e-19 -79.9971839578561 30.0192063612936 -2.6648667188285 0.00793709446261559 EMC9 other 3.26702574917205e-19 1 3.62536155713572e-15 9.34040501814078 -2.6648667188285 5.17102916332028e-06 27.561162920409 5.53451590235523 4.97986877383084 8.62200113945934e-07 26.6874926618749 13.8026969890359 1.93349840854103 0.0537070112633316 BRMS1L other 0.0322206827166486 1 0.00833057750094562 4.97986877383084 1.93349840854103 0.0566617642954954 33.099875276678 22.4120611175111 1.47687778929071 0.140300087727788 -90.2133272173094 64.1625896386463 -1.40601131789376 0.160304545407284 REC8 other 1 1 1 1.47687778929071 -1.40601131789376 7.95736821106295e-52 445.63787838449 41.6486229568441 10.6999426810883 2.4788493849263e-24 -1185.02772785959 119.234169931242 -9.9386587631964 1.83081535836335e-21 TM9SF1 other 1.20745105234669e-47 2.83208827785227e-17 3.53434345302792e-20 10.6999426810883 -9.9386587631964 0.000389384087910459 134.432772628649 48.0994977416665 2.79488932193561 0.00537953368201548 -198.667211009266 108.668258056548 -1.82819909477048 0.0680805510401216 SEC23A other 1 1 1 2.79488932193561 -1.82819909477048 1.22587648370783e-47 220.189139215279 27.1945745531997 8.09680397038503 3.84361981227932e-15 -819.704296884241 74.8674525972447 -10.9487403196941 2.62572208482178e-25 GMPR2 other 1.84298270560635e-43 4.08929957490144e-21 4.92675187537963e-11 8.09680397038503 -10.9487403196941 0.00108541445436535 138.689784539613 49.6843994061782 2.79141513628455 0.00543640637960914 -163.262670909666 112.276423579599 -1.454113568143 0.146504508570035 PNN essential 1 1 1 2.79141513628455 -1.454113568143 6.79063210586067e-29 133.410319207129 12.7742676829287 10.4436765001736 2.33268485642019e-23 -91.2317399385091 35.1679294833334 -2.59417433095529 0.00974221540427535 RABGGTA essential 9.20130650344121e-25 1 3.30564771003306e-19 10.4436765001736 -2.59417433095529 1.10309247064851e-07 108.597266621694 87.8226207587142 1.23655233336815 0.216797921603338 -1165.66216236033 236.431526650071 -4.93023150878503 1.09865614347669e-06 NFATC4 other 0.000795550289831709 0.0139265652747105 1 1.23655233336815 -4.93023150878503 0.0182686346830686 214.703683510919 76.7261985954817 2.7983099311734 0.0053219632314589 -62.9014853336079 492.949414988478 -0.127602312572129 0.898511558412771 PLTP other 1 1 1 2.7983099311734 -0.127602312572129 1.89154404211492e-22 124.255458747555 13.9301938488051 8.91986573167561 7.36371261749718e-18 -376.939318365685 88.2822502470638 -4.2697067339221 2.31533279903251e-05 PCIF1 other 2.35005431792357e-18 0.273000890333924 9.88652056025172e-14 8.91986573167561 -4.2697067339221 6.3837024559007e-92 545.818907626538 21.7744882289637 25.0668994782852 4.86791431485203e-92 -52.7573512307544 182.59877712678 -0.288924997532291 0.772751746413222 GSS other 9.95729909071391e-88 1 7.59686707975808e-88 25.0668994782852 -0.288924997532291 0.696875586140388 -297.975113235198 520.335926857685 -0.5726591185711 0.56711431530303 1780.79665275239 3247.8942059308 0.548292690537943 0.583717955721992 MMP9 other 1 1 1 -0.5726591185711 0.548292690537943 1.68106798033969e-102 679.580340932838 25.0502414357726 27.1286942553126 5.82326543963748e-102 -229.364181153835 210.620506362345 -1.08899263948803 0.276656756083778 TRPC4AP other 2.62650061248273e-98 1 9.10001690252149e-98 27.1286942553126 -1.08899263948803 1.84433516781169e-09 728.566621277084 135.361999412428 5.3823571197205 1.10015851013188e-07 -1153.41937877442 577.877000649756 -1.9959600009648 0.0464428374744819 PYGB other 1.49114498317575e-05 1 0.00112029141086729 5.3823571197205 -1.9959600009648 2.00995504413641e-14 384.563092478848 61.9445218678099 6.20818566167172 1.0733595121803e-09 -914.914344201082 264.448771878636 -3.45970350968756 0.000583747636143608 ABHD12 other 2.02945160806453e-10 1 1.19346844159327e-05 6.20818566167172 -3.45970350968756 0.476324131765874 -7.095109625442 7.03431336170415 -1.00864281424664 0.313601925561657 -45.4290755860357 56.4306010221806 -0.805043270196244 0.421152332315992 PROCR other 1 1 1 -1.00864281424664 -0.805043270196244 2.9031751827895e-15 142.992371653725 17.0684146127271 8.37760125343464 4.74112605087575e-16 90.3124433756973 72.8671583240784 1.23941217762371 0.215734282516863 GINS1 essential 3.02278600032043e-11 1 6.17484256866058e-12 8.37760125343464 1.23941217762371 4.24317878971384e-06 59.4976692837621 12.9640351593704 4.5894405987288 5.54130462535041e-06 -41.624468328086 55.2871862604167 -0.75287731468236 0.451854172841275 NINL other 0.0266641355145618 1 0.0508636351560914 4.5894405987288 -0.75287731468236 0.0571307473600711 16.4077447423037 9.91249574326871 1.65525869238791 0.0984562901996967 120.883600891912 61.9085914117419 1.9526143001371 0.0513844600046454 CD40 other 1 1 1 1.65525869238791 1.9526143001371 5.08643779597023e-28 165.417557798439 15.7511119745565 10.5019606276462 1.44790671186583e-23 -335.878836569655 88.3575297136718 -3.80136064982908 0.000160619215411529 UQCC1 other 6.82650816597165e-24 1 2.05429004279524e-19 10.5019606276462 -3.80136064982908 1.3840786486357e-10 258.540312182964 40.2738979465505 6.41955026369897 3.02118090581659e-10 -353.141195689928 245.96180101455 -1.43575626066032 0.151657209641679 ZMYND8 essential 1.18574017828621e-06 1 3.43055091855474e-06 6.41955026369897 -1.43575626066032 0.198910363634048 5.3768319290286 4.30981374773239 1.24757872236535 0.212737364062023 -29.9689644580897 27.4759818283734 -1.09073315906556 0.275886875408689 SGK2 other 1 1 1 1.24757872236535 -1.09073315906556 3.47752940601076e-30 138.822473585468 12.239752719035 11.3419344959129 7.71338452758271e-27 -257.502488236578 78.0310340484979 -3.3000009723892 0.00103199535959774 IFT52 other 4.76525854505654e-26 1 1.11635814267705e-22 11.3419344959129 -3.3000009723892 4.17805051895975e-11 460.65043497975 68.3889587298747 6.7357427797555 4.25764319072161e-11 1380.675382243 436.229154660614 3.16502317071668 0.00163978377065792 MYBL2 essential 3.67626665163269e-07 1 4.95376785240459e-07 6.7357427797555 3.16502317071668 3.07095146554628e-31 250.780832455956 20.9714096240084 11.9582248857921 2.44370569003348e-29 -356.076510939522 138.486637582644 -2.57119760545149 0.0104068776473939 NDRG3 other 4.25265358948848e-27 1 3.58125068874406e-25 11.9582248857921 -2.57119760545149 4.4642803037952e-17 53.6439622605729 5.96387322180606 8.99481935069165 4.21982172036387e-18 44.0565355562227 39.3829868504198 1.11866922952171 0.263788994599756 SLA2 other 4.91740475463042e-13 1 5.67819210692162e-14 8.99481935069165 1.11866922952171 6.19340042595894e-31 392.149723298415 31.0958376587262 12.6110036848732 4.50870691792346e-32 392.537767746629 205.394330292394 1.91114217801349 0.0565254341364672 C20orf24 other 8.54936994799372e-27 1 6.67514059198569e-28 12.6110036848732 1.91114217801349 0.0133328664598753 18.4886303681332 13.7208637076611 1.34748298372864 0.178402655131301 -264.82216393997 107.771766265827 -2.45724991911858 0.0143210027560345 NFATC2 other 1 1 1 1.34748298372864 -2.45724991911858 1.90776666161022e-09 500.461800556234 79.164096656152 6.32182797120747 5.43307540885748e-10 -258.214811348773 523.597273504823 -0.493155378026227 0.622104032182011 RIMS4 other 1.54147546258106e-05 1 6.10840668217846e-06 6.32182797120747 -0.493155378026227 3.07065035447724e-13 119.087087197884 16.2438872541933 7.3311939029337 8.38505745193669e-13 -184.018644866671 108.166800592312 -1.70124884769633 0.0894719340135213 PABPC1L other 2.96471291724777e-09 1 1.02029379075166e-08 7.3311939029337 -1.70124884769633 9.63790751713698e-29 198.545238387525 16.9673864268178 11.7015805141159 2.36735085013546e-28 -164.25684212996 114.083735186491 -1.43979193757508 0.150504657318464 STK4 other 1.30343061261761e-24 1 3.45491183068769e-24 11.7015805141159 -1.43979193757508 0.182505471693099 5.4645790070914 3.11077936397821 1.7566591415545 0.0795577677180647 -9.6643295575676 23.4255096883467 -0.412555785813925 0.680100197816021 SALL4 other 1 1 1 1.7566591415545 -0.412555785813925 9.57024839577999e-16 472.850153613955 58.211811466616 8.12292456978651 3.27337181054653e-15 -882.634796837483 461.75664658222 -1.91147177495002 0.056488138861388 ADNP other 1.0128193877254e-11 1 4.20039070729331e-11 8.12292456978651 -1.91147177495002 6.95613145084008e-37 115.431111097865 8.24540045389805 13.9994548164479 4.88196064444494e-38 57.4302284226396 63.3267122593314 0.906887889386315 0.364884525114816 PFDN4 other 1.00307415521114e-32 1 7.34539798563186e-34 13.9994548164479 0.906887889386315 0.782967358256562 -0.126720529926308 5.55636527715344 -0.0228063713606726 0.981813407620521 29.1179559903151 42.0085816564799 0.693143039877511 0.488526890436717 DOK5 other 1 1 1 -0.0228063713606726 0.693143039877511 3.93412747928766e-80 242.189518196254 10.6247749751844 22.7947903613884 1.2419290811754e-80 -18.2099236346118 84.7597169179322 -0.214841723129437 0.829973518248895 CSTF1 essential 6.11953529403196e-76 1 1.93467712265504e-76 22.7947903613884 -0.214841723129437 0.0103010429852215 40.8113941020689 13.6370771176296 2.99267898465641 0.00289356106294225 113.092666044132 138.34587699747 0.817463219711274 0.414029017221804 BMP7 other 1 1 1 2.99267898465641 0.817463219711274 1.26892313792206e-112 420.614370665282 14.3038563661422 29.4056623541671 1.15533958109337e-113 142.459372498068 136.779457651833 1.04152608106323 0.298103645637727 RAE1 essential 1.98446889539632e-108 1 1.80741324066247e-109 29.4056623541671 1.04152608106323 5.35437424604337e-72 866.70552785554 40.5092533245831 21.3952481649317 7.58201211126317e-73 1391.53337487448 313.76938197721 4.43489216859138 1.13036643457205e-05 TPD52L2 other 8.29499658197039e-68 0.136016993072055 1.1782446820903e-68 21.3952481649317 4.43489216859138 1.43817828905974e-40 610.132562143946 41.1483512954445 14.8276308268879 1.40891061698851e-41 897.11552873264 318.719593567962 2.81474859668878 0.00507138976890818 DNAJC5 other 2.11081427485297e-36 1 2.13520404004609e-37 14.8276308268879 2.81474859668878 7.02643169235396e-67 726.893238055151 35.8066809388423 20.3004919472062 4.0266937296407e-68 402.94274221112 274.156061315117 1.46975682492015 0.142224349200279 NELFCD essential 1.08565396078561e-62 1 6.24499930529977e-64 20.3004919472062 1.46975682492015 2.77684618428755e-08 657.690165779344 109.864152548472 5.98639456568118 3.97017222914801e-09 196.109590928094 841.181660870973 0.233135837418327 0.815746449320433 CTSZ other 0.000209271081525458 1 4.3131951097464e-05 5.98639456568118 0.233135837418327 1.56293853756037e-47 1014.81016779121 62.0034139468418 16.3670047049546 1.34532492742204e-48 375.283194256141 475.161958775083 0.789800587621916 0.430015653641471 PRPF6 essential 2.34925291580699e-43 1 2.05901980141944e-44 16.3670047049546 0.789800587621916 0.000978941985579428 5.41167170074703 1.54145960751591 3.51074505900808 0.000485154538352113 -11.2277154934075 11.8022805686656 -0.951317453273938 0.341879336221027 TUBB1 other 1 1 1 3.51074505900808 -0.951317453273938 1.65146810568768e-45 557.060665048974 35.1250479622138 15.8593567088716 1.40227605498386e-46 161.651925430676 268.872899669174 0.601220597648835 0.54795206877075 PRELID3B other 2.46977055205592e-41 1 2.14085485314385e-42 15.8593567088716 0.601220597648835 9.8163255718656e-52 227.401445539389 13.216762702449 17.2055329023387 7.2525579892319e-53 123.655226493783 97.5196100149878 1.26800370176602 0.205362977503784 MTG2 essential 1.48913658925201e-47 1 1.11464563736505e-48 17.2055329023387 1.26800370176602 1.46837104486307e-53 1068.73361363353 61.1052626868351 17.4900420461458 3.61415272044758e-54 1868.51896020489 434.596026782603 4.29943866269991 2.04650805400297e-05 PSMA7 essential 2.23486073028159e-49 0.242449809157732 5.56109679095269e-50 17.4900420461458 4.29943866269991 1.85914294597498e-20 48.4730029927056 4.88555048745148 9.92170751631947 2.369381688222e-21 78.7127835331363 35.5659974750028 2.21314708208195 0.0273243078037154 SLCO4A1 other 2.22111807755631e-16 1 3.29699461916091e-17 9.92170751631947 2.21314708208195 1.57951209759111e-57 176.388295922379 9.55907927564656 18.4524357248254 9.23442740897632e-59 193.433662073657 69.0031263455614 2.8032593929869 0.00524931091694399 MRGBP essential 2.41870687504127e-53 1 1.42598028049412e-54 18.4524357248254 2.8032593929869 1.46887251306573e-41 98.6299710736785 6.54806881207631 15.0624518318713 9.29120884544493e-43 92.6322624352502 47.2678598565729 1.95973041124199 0.0505651784914952 TCFL5 other 2.16570563326411e-37 1 1.41105588735772e-38 15.0624518318713 1.95973041124199 4.67016135471159e-41 423.563418966526 28.7311822323835 14.7422899461867 2.64914622272052e-41 -116.781430128334 208.618224714511 -0.55978537008522 0.575868757644826 DIDO1 essential 6.86980735278075e-37 1 4.01345652742158e-37 14.7422899461867 -0.55978537008522 2.78679882671504e-63 718.780326210761 36.5909932098555 19.6436407748878 1.56084615269379e-64 563.514454394069 263.737384707334 2.13664989140388 0.0330970975348268 GID8 other 4.2961290712639e-59 1 2.41650201360052e-60 19.6436407748878 2.13664989140388 4.0085679610563e-15 113.332086907521 13.4770350293718 8.40927449253677 4.09002905609495e-16 82.1413113284757 95.7884268156123 0.857528555997619 0.391552495181032 SLC17A9 other 4.15447983483874e-11 1 5.33257988333659e-12 8.40927449253677 0.857528555997619 2.01427904427129e-38 571.949934733257 40.2555582892702 14.2079742286348 6.65463031689615e-39 -84.097829713824 284.034936328033 -0.296082696026868 0.76728604975453 ARFGAP1 other 2.92916458617931e-34 1 1.00391752960695e-34 14.2079742286348 -0.296082696026868 3.03787051082498e-09 1421.44103694056 224.411738300566 6.33407613926484 5.22448492774089e-10 -10.8256118688678 1605.07506126837 -0.00674461408696557 0.994621239296242 EEF1A2 other 2.42300551943401e-05 1 5.8796353376796e-06 6.33407613926484 -0.00674461408696557 3.45542961565258e-13 114.809820220045 14.8035433899687 7.75556346177517 4.78775393370304e-14 21.6949022902164 105.143744701142 0.206335644140138 0.836610760767424 PTK6 other 3.32619654802717e-09 1 6.00863118679731e-10 7.75556346177517 0.206335644140138 1.06530828166496e-25 79.8606861401192 7.13769724168415 11.1885785339469 3.83038705253732e-26 -27.5437230715706 51.1883807704314 -0.538085453319927 0.590752334834605 GMEB2 other 1.38958812260377e-21 1 5.52188597493779e-22 11.1885785339469 -0.538085453319927 4.00734533763823e-16 212.319981744561 25.5333450590171 8.31540016608909 7.92861386535e-16 -32.8360478624769 102.706825458997 -0.319706579535806 0.749318197619403 C20orf27 other 4.28866098034043e-12 1 1.02857907675186e-11 8.31540016608909 -0.319706579535806 1.23348021948576e-06 13.2399156703369 5.01212991978834 2.64157471618293 0.00849539257701662 -76.2142278644917 20.4037818652573 -3.73529909150156 0.000207781991782181 SPEF1 other 0.00816563905299573 1 1 2.64157471618293 -3.73529909150156 6.92226197827457e-08 376.756135776608 65.8684776319332 5.71982455525821 1.75980032375441e-08 687.198664350525 265.541816738987 2.58791128564885 0.00991351848863506 CDC25B other 0.000506363463710785 1 0.00018652123631473 5.71982455525821 2.58791128564885 0.116036998805528 -0.631386288666445 19.7181379500162 -0.032020583802941 0.97446748918473 161.435913302474 80.6170704817905 2.00250284880965 0.0457310850063788 ISM1 other 1 1 1 -0.032020583802941 2.00250284880965 3.98829025626829e-10 294.838123742721 46.0135319726552 6.40763947262158 3.19972608457274e-10 -41.5711927872537 181.378234559714 -0.229196148524466 0.818802449433719 RNF24 other 3.33740128644531e-06 1 3.63168910599006e-06 6.40763947262158 -0.229196148524466 5.07705492665553e-38 241.8249525069 17.077841743788 14.1601588851157 1.26039698495574e-38 -34.5584287568527 132.82522852266 -0.260179704874041 0.794830165462634 ARFRP1 other 7.37036063702584e-34 1 1.90030053421777e-34 14.1601588851157 -0.260179704874041 3.17526137400376e-22 40.0142361889008 4.08826126243559 9.78759272470327 6.32278218958486e-21 -16.1285084840774 17.0215165796865 -0.947536514068621 0.343791648748981 NDUFAF5 other 3.92875089805485e-18 1 8.77096345339212e-17 9.78759272470327 -0.947536514068621 1.98710315460502e-12 229.526082210556 37.2973460994526 6.1539521229883 1.47572546460136e-09 -329.091013043654 138.185356578032 -2.38151871654953 0.0175875552313508 TRIB3 other 1.85555692577016e-08 1 1.63052906583805e-05 6.1539521229883 -2.38151871654953 0.824488801931467 -12.8314413014098 23.5335640888767 -0.545240034741473 0.585811092702602 -41.836724681641 97.8729801797856 -0.42745939282517 0.669213283569622 RASSF2 other 1 1 1 -0.545240034741473 -0.42745939282517 3.30685172423926e-32 413.504506560233 37.4942621859322 11.0284742905377 1.21568208789562e-25 -448.645768523116 138.914923758323 -3.22964413315049 0.00131496808528573 CSNK2A1 other 4.61702637738286e-28 1 1.74705672851479e-21 11.0284742905377 -3.22964413315049 8.89346275617878e-10 104.744154914929 24.6634222610863 4.24694325897316 2.54885856137345e-05 -326.768979083139 90.8921341813524 -3.59512934783942 0.000353715531846192 SLC52A3 other 7.29619684516907e-06 1 0.222184000794924 4.24694325897316 -3.59512934783942 7.44319254743317e-06 4.07665428290288 4.87185445860611 0.836776697157176 0.403084178797159 86.9828489993062 17.8353672720024 4.87698670135323 1.41492799486548e-06 RSPO4 other 0.0457607477816192 0.0178379972312692 1 0.836776697157176 4.87698670135323 3.62123744177117e-10 159.826307362272 45.4299016804941 3.51808613820741 0.000470889742801872 -890.436530393437 188.708684506065 -4.71857738144964 3.0211551060264e-06 CDS2 other 3.03713184241348e-06 0.0375197252617418 1 3.51808613820741 -4.71857738144964 3.98424465870684e-14 671.156638934566 85.1714629152536 7.88006470667733 1.923080133595e-14 -471.099509728594 501.993478257396 -0.938457430490837 0.348444230046308 HM13 other 3.97786986725291e-10 1 2.4321194449576e-10 7.88006470667733 -0.938457430490837 0.319572964315771 -8.96829223671112 33.5489005322379 -0.267320004364772 0.789323727880214 -184.934071949762 123.181072214502 -1.50131890090814 0.133851159476276 SNPH other 1 1 1 -0.267320004364772 -1.50131890090814 0.634110033031485 21.7400145393365 23.2899919266802 0.933448779534865 0.351014966956166 -12.9955028551886 139.490265780081 -0.0931642275001266 0.925808432547935 MYLK2 other 1 1 1 0.933448779534865 -0.0931642275001266 0.0804925530511538 9.80843903721532 4.48563337469534 2.18663413121263 0.029191373064394 19.0604601494679 16.6321662203914 1.14599985936284 0.252295387709442 SIRPB1 other 1 1 1 2.18663413121263 1.14599985936284 1.50119684876498e-30 371.626866376745 35.6496402175254 10.4244212314393 2.56621588190896e-23 -1062.93351072238 218.469928365409 -4.86535386666369 1.49923774194294e-06 SEC23B other 2.06414566705184e-26 0.0188843985975133 3.63401831037128e-19 10.4244212314393 -4.86535386666369 0.392119758846587 12.9889730728617 16.0928888675911 0.807125009047924 0.419945273342673 83.0232942305851 65.2976604873793 1.2714589406558 0.204105782298048 FERMT1 other 1 1 1 0.807125009047924 1.2714589406558 0.889818524179033 -1.68452339870514 3.70668070143641 -0.454456030715664 0.649686346750758 2.19030255403761 21.5158670093208 0.101799409388836 0.918954323072987 CCM2L other 1 1 1 -0.454456030715664 0.101799409388836 0.34445484322259 41.1374163328918 28.1767381454857 1.45997794778395 0.144880891870246 45.5047964248707 110.519816700824 0.411734273393267 0.680698488316609 PLCB4 other 1 1 1 1.45997794778395 0.411734273393267 0.0014076352268802 -34.45767455552 186.91028475575 -0.184354085172726 0.853806202936011 4423.49525677916 1234.58043431722 3.58299478415561 0.00037099390418122 MYL9 other 1 1 1 -0.184354085172726 3.58299478415561 0.234425914317416 2.81598091045048 16.153327214376 0.174328228053496 0.86167395940536 159.843103232295 93.7639003995875 1.70474033771101 0.0888277935142437 HCK other 1 1 1 0.174328228053496 1.70474033771101 2.96975427415913e-24 397.402985344605 39.8922706075381 9.96190438128411 1.49298750184014e-21 -740.571826175743 232.574565778338 -3.18423394104739 0.00153617943394557 TM9SF4 other 3.79475201152054e-20 1 2.08197107131607e-17 9.96190438128411 -3.18423394104739 6.50686775390682e-14 28.1057608595941 3.55101858638312 7.91484476239284 1.45705085381739e-14 55.2763072655331 23.438991966121 2.35830565347819 0.018720743604466 TLDC2 other 6.44700457057088e-10 1 1.84812330298198e-10 7.91484476239284 2.35830565347819 2.50791973926746e-28 235.093765597179 28.7754575748828 8.16994012989687 2.17186442596717e-15 -796.227613531861 125.610816672327 -6.33884592605531 4.86449954560557e-10 CRNKL1 essential 3.3766631369497e-24 6.85991725921298e-06 2.79627544843273e-11 8.16994012989687 -6.33884592605531 1.97261288833953e-15 435.553250876948 51.7778972062277 8.41195325376328 3.76090506712992e-16 798.871037006583 341.767210482427 2.33747127431834 0.0197859767187604 SAMHD1 other 2.06473391022498e-11 1 4.90835720311126e-12 8.41195325376328 2.33747127431834 0.747598673235212 -1.13850315124376 1.4930725893782 -0.762523643755253 0.446081718617258 -1.21737312481819 5.94188529108308 -0.204879943853021 0.837743413540037 PAK5 other 1 1 1 -0.762523643755253 -0.204879943853021 7.11107557274813e-21 432.772283502208 50.055299940742 8.64588333332427 6.19690587585107e-17 -1126.45867214134 287.984802498746 -3.91152124128581 0.000103505280420833 KIF3B other 8.57666824829152e-17 1 8.20160492668889e-13 8.64588333332427 -3.91152124128581 1.27734988851185e-28 32.1544029787138 2.71901492714477 11.8257544884018 8.21989082227422e-29 -12.7962446990806 17.9771721575914 -0.71180520422824 0.476897419699744 MROH8 other 1.72506102443526e-24 1 1.20166583930827e-24 11.8257544884018 -0.71180520422824 3.78958922325152e-28 175.114887460084 16.7784474482076 10.4368945935335 2.49584671107078e-23 -483.519777200152 111.919654505556 -4.32024008058519 1.85957580929893e-05 MANBAL other 5.09358687497237e-24 0.220880414628527 3.53486769688955e-19 10.4368945935335 -4.32024008058519 1.5544301934541e-24 282.348075145242 30.594111460903 9.2288372390243 5.91640120196937e-19 -361.267105430912 113.772224522572 -3.17535415121673 0.00158065975305416 IDH3B other 1.99557748235637e-20 1 8.04216415383697e-15 9.2288372390243 -3.17535415121673 1.93060975411496e-42 781.994337545124 52.8854025416749 14.7865819292742 7.8484930105384e-42 -395.279079214448 302.960403358739 -1.3047219201989 0.192539217299518 MAPRE1 other 2.85710937511473e-38 1 1.18983154039762e-37 14.7865819292742 -1.3047219201989 0.42097745073017 14.2239058413362 76.8505245847159 0.185085344806677 0.853231718641442 -364.748770866308 299.11788618014 -1.21941477831467 0.223220144696191 JAG1 other 1 1 1 0.185085344806677 -1.21941477831467 1.73143090725042e-28 134.760330116459 11.8065931871816 11.4139894531784 3.43296826424289e-27 -140.924072634566 69.2065385656024 -2.03628263391588 0.0422075913520012 CDK5RAP1 other 2.33483457842719e-24 1 4.97814727997861e-23 11.4139894531784 -2.03628263391588 1.51110707388181e-06 90.4064534057129 17.7138719121921 5.10370933321969 4.61608793448186e-07 -46.1561108113221 103.83314985124 -0.444521916916216 0.656842729806716 SNTA1 other 0.00992344015418184 1 0.00453899926597601 5.10370933321969 -0.444521916916216 6.2450755457171e-57 210.301707092953 11.6638819528528 18.0301642234571 3.90916413323096e-57 -26.0896353854804 79.6697049838051 -0.327472473894359 0.743438657721847 TTI1 essential 9.55746361516545e-53 1 6.03027659192207e-53 18.0301642234571 -0.327472473894359 3.27969277211291e-10 156.355968173233 23.2331146795616 6.72987545276402 4.44167262809058e-11 76.7059665420659 133.232792721039 0.575728880071378 0.565044206891732 E2F1 other 2.75723771351532e-06 1 5.16477693194373e-07 6.72987545276402 0.575728880071378 1.82583932278853e-55 272.903588108464 15.6817905224457 17.4025783419216 4.41375226045424e-54 -212.927572023763 107.52094557067 -1.98033574661798 0.0481776564755667 RPRD1B essential 2.78641339050758e-51 1 6.79055785270885e-50 17.4025783419216 -1.98033574661798 0.0324284422961581 70.137796643954 37.9734246989666 1.84702320635996 0.065304135832398 -338.055894645223 217.762684496028 -1.55240506621964 0.121165632887785 PXMP4 other 1 1 1 1.84702320635996 -1.55240506621964 2.37949602341245e-15 547.750061335229 82.2338766078469 6.66088094019104 6.8495526483554e-11 -1947.80318419224 474.175280629527 -4.10777040424015 4.62952489641003e-05 CHMP4B essential 2.48443179804494e-11 0.535450849518784 7.92424745888236e-07 6.66088094019104 -4.10777040424015 0.511571809853284 -2.89144512049982 3.12357557368131 -0.925684380702238 0.355029741031009 -11.9184472078986 13.1825737025915 -0.904106244864435 0.366348283534688 CST9L other 1 1 1 -0.925684380702238 -0.904106244864435 0.0230123837271725 293.62612555544 362.401957613055 0.810222239110945 0.418174727216461 -3597.29335301172 1529.46211913391 -2.35199898579297 0.0190363802433637 CST3 other 1 1 1 0.810222239110945 -2.35199898579297 0.316617862164037 7.09868981861193 32.3058761645731 0.219733703628704 0.826162681856922 -194.739444430914 138.585722834306 -1.40519124515983 0.16054698341484 CST4 other 1 1 1 0.219733703628704 -1.40519124515983 3.13236467132272e-39 60.4829185193117 4.35110316557429 13.9005939913927 1.0489403299999e-37 -51.1261591502193 25.9030912743093 -1.97374740369024 0.0489264799487328 ACTR5 other 4.57137300132838e-35 1 1.57729157422086e-33 13.9005939913927 -1.97374740369024 0.162932259025126 307.499130832296 188.081727872909 1.63492293648047 0.102646885812995 -951.244030111193 1244.21955892704 -0.764530683741626 0.444884396633411 WFDC2 other 1 1 1 1.63492293648047 -0.764530683741626 3.4228008665268e-11 821.452045635221 119.912785866274 6.85041248688275 2.0678138294452e-11 -437.162136648677 655.415599751481 -0.666999895660767 0.505065237446985 AHCY essential 3.02301772531647e-07 1 2.43071515651283e-07 6.85041248688275 -0.666999895660767 0.330319132353274 -7.95830288744834 14.8724762970448 -0.535102744727834 0.592801982599985 -128.902543143362 88.5391810622597 -1.45588135779932 0.14601417362712 PPP1R16B other 1 1 1 -0.535102744727834 -1.45588135779932 1.58127519491222e-12 137.604377346273 20.3784178255292 6.75245637440449 3.81626749496571e-11 530.43724648019 119.211967980463 4.44953015595819 1.04869259826706e-05 FAM83D other 1.48276175026919e-08 0.126472327351007 4.44747813863304e-07 6.75245637440449 4.44953015595819 9.11951334980378e-26 50.9890416515517 4.95924139660885 10.2816212347353 9.79184721135904e-23 -89.6722270370736 29.0123577234928 -3.09082867003468 0.00210069228872108 DHX35 other 1.19091724835088e-21 1 1.37937751666415e-18 10.2816212347353 -3.09082867003468 4.17238985635448e-33 162.787946594408 12.5771995057913 12.9430996558058 1.45229427603847e-33 -25.6553900669471 82.4504054309277 -0.311161478622925 0.755797947165646 DNTTIP1 other 5.87055252789075e-29 1 2.16130434160045e-29 12.9430996558058 -0.311161478622925 0.335932337922551 19.8822603390526 14.4454480776849 1.3763685440652 0.169294301960229 -24.4494987018403 80.0034405077154 -0.305605590793091 0.76002609751697 MAP1LC3A other 1 1 1 1.3763685440652 -0.305605590793091 0.00234676767088563 -23.7545678299364 9.87986657494056 -2.40434095437967 0.0165405495554533 -130.873085068209 42.523014057945 -3.07770011057709 0.00219293399069207 SYNDIG1 other 1 1 1 -2.40434095437967 -3.07770011057709 2.65197521918666e-24 140.286209375049 13.3307135255629 10.5235334257268 1.22972408664643e-23 -118.407906687009 81.1426780621296 -1.45925559169178 0.145090553307562 PIGU other 3.39240670038358e-20 1 1.74547036858594e-19 10.5235334257268 -1.45925559169178 0.762028241544109 106.584230725618 153.513571860916 0.694298422175882 0.487793665196181 -154.88947042342 1006.36522727132 -0.153909799569875 0.877738358050909 TNNC2 other 1 1 1 0.694298422175882 -0.153909799569875 1.55166698922163e-37 140.077950928375 10.1798340114083 13.760337425089 3.88362563075011e-37 -90.607459151015 65.4712942234932 -1.38392650131089 0.166953744925915 ACOT8 other 2.24650346699508e-33 1 5.83204060969743e-33 13.760337425089 -1.38392650131089 4.93993267363355e-22 768.652958824298 109.201033464666 7.03887989368721 5.95583620362616e-12 -2558.22982448514 465.956184982231 -5.49027978796482 6.20320782151439e-08 APMAP other 6.0919249731249e-18 0.000826639474295008 7.10650375816673e-08 7.03887989368721 -5.49027978796482 0.721894819477054 19.1151929357991 24.0577672154799 0.794553907043354 0.427219526523627 22.9402389175698 51.9000201629343 0.442008285267549 0.658658870258383 CELF4 other 1 1 1 0.794553907043354 0.442008285267549 1.17267727408878e-13 95.8536196918493 40.623720178568 2.35954804903415 0.0186567999761088 -483.624729952759 82.9701182964331 -5.82890249987205 9.67042681983304e-09 ZNF516 other 1.15098274451813e-09 0.000132291438895316 1 2.35954804903415 -5.82890249987205 1.68133948799859e-14 187.910165882417 29.6417788067378 6.33936873719952 5.05339955262397e-10 -115.651149149768 61.0178881353027 -1.89536466574065 0.0586048700332845 ADNP2 other 1.70286063344497e-10 1 5.69012789625459e-06 6.33936873719952 -1.89536466574065 1.1324649976271e-24 95.9471484996791 16.0740790705559 5.96906037842209 4.45110553600291e-09 -190.458455788459 33.088647108528 -5.75600613599496 1.48217678086853e-08 RBFA other 1.4568029729475e-20 0.000201561220430311 4.82722395379516e-05 5.96906037842209 -5.75600613599496 4.70088757094328e-09 489.310491462291 155.823436545812 3.14015980079115 0.00178418938513044 -1157.96348390426 341.762965328504 -3.38820645119117 0.000756645293417702 USP14 other 3.71182082601681e-05 1 1 3.14015980079115 -3.38820645119117 5.18320386256539e-33 462.029855156665 78.5583600807749 5.88135819894405 7.15250531829028e-09 -1367.66308788006 173.703236042055 -7.87356136271947 1.9126860442158e-14 VAPA other 7.28965791231197e-29 2.85812675587167e-10 7.70324822779864e-05 5.88135819894405 -7.87356136271947 9.02709084137109e-24 74.9211843202667 8.76752980980232 8.54530135004536 1.37680281535834e-16 -40.578238456718 19.6108916117142 -2.06916846312482 0.0390153454612073 METTL4 other 1.14499620231951e-19 1 1.809669620507e-12 8.54530135004536 -2.06916846312482 4.44135974640299e-07 287.354576836208 64.8515783551135 4.43095733557501 1.13928195190047e-05 -125.991505377398 147.148773306421 -0.856218523242698 0.392261678309572 LPIN2 other 0.00305743204942382 1 0.102216376724511 4.43095733557501 -0.856218523242698 1.64657035212111e-11 254.884755130079 55.6513295090443 4.58002993600819 5.80069907450303e-06 -373.79520787572 127.409884912136 -2.93380068692076 0.00349338996840296 SMCHD1 other 1.47565634957094e-07 1 0.0531866098141183 4.58002993600819 -2.93380068692076 0.131643714141468 115.337709743996 149.315956272731 0.77244061936239 0.440195877811609 681.360154088868 338.799152740668 2.01110347702201 0.0448175123758943 MYOM1 other 1 1 1 0.77244061936239 2.01110347702201 9.11004343811866e-17 1232.83705938204 168.383768856873 7.32159083830674 9.09351389869012e-13 -446.581342312491 382.064178859682 -1.16886472750565 0.242980631107509 MYL12A other 9.93450236926839e-13 1 1.10558941980274e-08 7.32159083830674 -1.16886472750565 1.38135362535792e-22 43.7905580423517 5.88892698221756 7.43608439611892 4.20944625068091e-13 -53.1461427699439 14.1429156331232 -3.75779253363243 0.000190485580627357 CEP76 other 1.71923272212046e-18 1 5.15993921408466e-09 7.43608439611892 -3.75779253363243 3.05532664183762e-15 137.097106380652 26.120118240767 5.24871691302979 2.21965799373422e-07 -242.495814267622 62.8327353869687 -3.85938655661194 0.000127689488891523 CEP192 essential 3.17937290349622e-11 1 0.00222387534392232 5.24871691302979 -3.85938655661194 5.87691464580876e-19 185.333751481819 31.8718511984363 5.81496664024686 1.05429036294498e-08 -330.818597081057 74.092347897993 -4.46494957261326 9.81026599269352e-06 RNMT essential 6.78548565005079e-15 0.118508013191738 0.000112735268509707 5.81496664024686 -4.46494957261326 3.43024823736096e-10 114.490423555115 29.6259860203359 3.8645270228821 0.000124836983196116 -206.21651947294 62.1566323464449 -3.31769131769467 0.000968766776500277 SMAD7 other 2.88037944491199e-06 1 1 3.8645270228821 -3.31769131769467 0.0588074099240683 52.347328865825 22.0631078498824 2.37261809270011 0.0180118251871784 56.7411488422764 45.0898359075599 1.25840220307307 0.208790140303912 LIPG other 1 1 1 2.37261809270011 1.25840220307307 0.0591913645370289 57.2542244881438 24.6081569933018 2.32663602169509 0.02035575270521 23.9632431322443 56.3798951546257 0.425031707961206 0.670983816647619 LAMA1 other 1 1 1 2.32663602169509 0.425031707961206 8.71076226307436e-05 24.9764445345953 12.1070590800242 2.06296544598553 0.0395925416307557 -93.6808138672547 31.5803517044919 -2.96642718687423 0.00314593400821446 RNF125 other 0.47674001865806 1 1 2.06296544598553 -2.96642718687423 8.79135774054472e-15 104.982688606969 52.7246272662438 1.99115089191313 0.0469695872087637 -705.110762949278 112.339035338085 -6.27663181215008 7.12785490121399e-10 ANKRD12 other 9.00059205476969e-11 1.00189128491464e-05 1 1.99115089191313 -6.27663181215008 1.31129905677929e-08 45.416831084831 7.43762586611779 6.10636134465005 1.94734541130761e-09 44.8082365476242 16.20799482872 2.76457618731625 0.00589410736099945 NOL4 other 0.000100615976626675 1 2.14169048335611e-05 6.10636134465005 2.76457618731625 8.97932553654762e-26 58.685532122336 27.5957572960589 2.12661430134832 0.0339057981850338 -526.026555491508 57.5034692148236 -9.14773600052474 1.18935919280166e-18 POLI other 1.17287950158385e-21 1.82340657848423e-14 1 2.12661430134832 -9.14773600052474 5.72616575545752e-09 324.530407403999 80.0913699663015 4.05200220124272 5.87315168112868e-05 -528.102339604119 183.259330525422 -2.88172142771667 0.00412244005989708 MIB1 other 4.49904843406297e-05 1 0.495635270370449 4.05200220124272 -2.88172142771667 9.56146651887972e-19 340.109695198183 43.6808734731243 7.78623841868556 3.72766381630576e-14 -216.090805292743 99.67619297468 -2.16792795595268 0.0306144711147002 RIOK3 other 1.09889934701485e-14 1 4.69014661367591e-10 7.78623841868556 -2.16792795595268 2.21787431978153e-05 86.6866590727507 27.4345292780154 3.15976476921792 0.0016684161614286 -195.11402741915 77.6062968636522 -2.5141520122001 0.012224825644801 EEA1 other 0.130255758800769 1 1 3.15976476921792 -2.5141520122001 0.0461811096833955 -5.93066276749349 8.85684949059253 -0.669613136566546 0.503390116076897 27.9921748368623 16.5123997037475 1.69522149046025 0.0906088198833543 RUBCNL other 1 1 1 -0.669613136566546 1.69522149046025 3.67856569250831e-14 68.9965891148662 8.56892268547253 8.05195607982795 5.21411584049437e-15 71.7062759805031 20.6721165586867 3.46874379200281 0.000564555179479215 NALCN other 3.67856569250831e-10 1 6.665725690488e-11 8.05195607982795 3.46874379200281 8.64354580070959e-05 -187.617440342324 60.0403742461442 -3.12485461155121 0.00187486619396994 -552.8072947008 141.818359345646 -3.89799527544577 0.00010924132121132 FGF14 other 0.473407003504864 1 1 -3.12485461155121 -3.89799527544577 0.383720537086107 0.20127407841478 2.78959292476475 0.072151774055619 0.942507838915602 6.26089628186445 5.15916868957934 1.21354750320733 0.225451088602186 HTR2A other 1 1 1 0.072151774055619 1.21354750320733 1.43584080113285e-46 249.198741044096 21.7074202335141 11.4798874469366 2.31877439707291e-27 -244.698584386685 45.0008413277372 -5.43764465656469 8.29890489469715e-08 NDFIP2 other 2.15218177681803e-42 0.0011015966357221 3.36662854711016e-23 11.4798874469366 -5.43764465656469 0.0934101624317811 36.4847231989461 21.4762163575313 1.69884315707928 0.0899268724405415 95.2327183574423 50.9417023200398 1.86944515044168 0.0621039022229121 TNFSF13B other 1 1 1 1.69884315707928 1.86944515044168 7.93255435279505e-15 65.7921774187293 56.5371203274389 1.1636987706075 0.245062895360288 -661.427866557769 104.317935920287 -6.34049994109534 4.86082108961359e-10 FNDC3A other 8.139594021403e-11 6.85521598268204e-06 1 1.1636987706075 -6.34049994109534 3.18982830881277e-31 17.9289996188719 3.96225814996793 4.52494485222196 7.44049920704083e-06 -55.7034347252416 7.33833420369213 -7.59074650718627 1.41301127343091e-13 CDADC1 other 4.4159983107204e-27 2.09464791173397e-09 0.0676862212864505 4.52494485222196 -7.59074650718627 3.34235279853887e-12 13.5371747372014 44.0149080308035 0.307558855461597 0.758536613897681 -499.021353227691 81.4104293363768 -6.12969809022629 1.70013511293036e-09 CAB39L other 3.0956871620067e-08 2.36964832040234e-05 1 0.307558855461597 -6.12969809022629 0.000248937803860633 303.888599930293 77.3853110526637 3.92695455760959 9.79074332851459e-05 415.249681342296 144.960081955562 2.86457951554961 0.00434847854689165 KLF5 other 1 1 0.809890288134727 3.92695455760959 2.86457951554961 1.18564049177335e-50 1658.69831356767 103.833279804093 15.9746308379858 2.7774145076177e-47 -6.20429213195733 255.02970894853 -0.0243277230622942 0.980600237074544 STK24 other 1.79612678098745e-46 1 4.24250066038604e-43 15.9746308379858 -0.0243277230622942 0.71645444161811 18.2099322091393 171.584537418115 0.106128049083849 0.915520169306452 -462.871921871883 613.474608685346 -0.754508687594749 0.450872736894012 ACP5 other 1 1 1 0.106128049083849 -0.754508687594749 4.05924909469487e-22 448.347443263394 62.6996701790903 7.150714540966 2.84398741124282e-12 -742.241174194496 157.593255868616 -4.70985366793422 3.16179031413306e-06 DNAJC3 other 5.01276670703869e-18 0.0392251706371348 3.42273884943074e-08 7.150714540966 -4.70985366793422 5.22871381355029e-44 164.342554765755 11.947044098277 13.7559176490741 4.32576978225983e-37 -66.6510409808263 30.037627230366 -2.21891830768333 0.0269103122539732 UGGT2 other 7.78084902594419e-40 1 6.49557590504136e-33 13.7559176490741 -2.21891830768333 1.42241538944227e-49 375.410386555308 24.2457597246216 15.4835480850731 4.28104563851059e-45 -144.635325604755 69.8873544705202 -2.06954930116528 0.0389643711488685 ARHGEF7 other 2.14827396267465e-45 1 6.52174492570703e-41 15.4835480850731 -2.06954930116528 0.0420600628767473 13.1335049502677 13.6259547578157 0.963859427372198 0.335551051920434 -42.6664984270338 27.2926183395538 -1.56329810120121 0.118572683832913 SGCG other 1 1 1 0.963859427372198 -1.56329810120121 1.5309887891354e-16 467.49101315225 58.6484293901544 7.97107472464948 9.24562455040289e-15 52.2660388877591 127.816094754392 0.408915942770681 0.682761690778429 PARP4 other 1.65806085863363e-12 1 1.17780011147582e-10 7.97107472464948 0.408915942770681 5.47417686931264e-38 230.437571647929 27.0651801769236 8.51417098063161 1.68916005632873e-16 -277.81975443984 51.7777004243767 -5.36562559099368 1.20147503171087e-07 SUPT20H other 7.9457677258073e-34 0.00158498586183298 2.2171914899371e-12 8.51417098063161 -5.36562559099368 1.46906826004653e-52 65.5600376863738 7.39901665927016 8.86064198872078 1.1351569396085e-17 -109.850089581106 13.9459249807101 -7.87685935017222 1.84069763774628e-14 MRPS31 essential 2.2319554074887e-48 2.75110668937558e-10 1.51883998519617e-13 8.86064198872078 -7.87685935017222 1.22634174430351e-16 38.6712821765092 7.76994986059919 4.97703110963538 8.67755958069076e-07 -53.2234260693989 14.6882398218117 -3.62354010521828 0.000317843859759589 SLC25A15 other 1.33278820770905e-12 1 0.00838214819114784 4.97703110963538 -3.62354010521828 8.60594593877382e-15 281.581546121268 39.6310864271259 7.10506754941083 3.81865382973972e-12 12.8249972891602 73.3020675367858 0.174960921569151 0.861175920068381 KPNA3 other 8.81507042508603e-11 1 4.58162086492172e-08 7.10506754941083 0.174960921569151 0.265807067353477 -71.428852832738 48.4399236902892 -1.47458640293146 0.140916395897892 -6.52329820651193 104.218573358191 -0.0625924726880678 0.950114576920331 FLT1 other 1 1 1 -1.47458640293146 -0.0625924726880678 0.00698440489930281 84.3169393275766 31.9809876088826 2.63647077941264 0.00861665357329919 -7.51746701100823 59.8527680225068 -0.125599320789665 0.900095502918761 RGCC other 1 1 1 2.63647077941264 -0.125599320789665 4.19869597474098e-07 112.824225112053 27.8718229863552 4.04796719494405 5.91759676695949e-05 -57.8029711847542 53.6212357764424 -1.07798655416571 0.281518402437081 DGKH other 0.00289710022257127 1 0.499267639228372 4.04796719494405 -1.07798655416571 2.09294517612149e-06 57.1866982165334 13.4920314916515 4.23855356785364 2.65791684961477e-05 -20.177429116679 29.2687824911265 -0.689383957901092 0.490886250171429 KATNAL1 other 0.0135790283026762 1 0.231318503421973 4.23855356785364 -0.689383957901092 3.93114808584615e-23 98.6584785853225 26.2759676856844 3.75470390911895 0.000192564229484692 -320.651837854912 48.4202924295943 -6.62226148925384 8.62632112518283e-11 INTS6 other 4.93791511063135e-19 1.23434028980241e-06 1 3.75470390911895 -6.62226148925384 1.2794998321076e-39 27.0836877670242 9.65324219168822 2.80565712837332 0.00520455889474661 -193.74804279503 17.7992551908302 -10.8851769761043 4.65213878538552e-25 DHRS12 other 1.87075670452452e-35 7.24291487496672e-21 1 2.80565712837332 -10.8851769761043 0.889768364360667 8.0694726029519 23.4647804706171 0.343897212806087 0.731060236256572 -6.33897139839043 47.843943770893 -0.132492660486883 0.894645007891709 MEDAG other 1 1 1 0.343897212806087 -0.132492660486883 1.36343756006189e-18 228.19236118175 148.880858043089 1.53271793420015 0.125927759432571 -2046.83087061546 285.12910715199 -7.17861073904456 2.32728183493664e-12 TSC22D1 other 1.56059063124684e-14 3.40737333453074e-08 1 1.53271793420015 -7.17861073904456 2.29315577242507e-26 126.931381086262 26.7137679816833 4.75153415921312 2.61331618962331e-06 -392.449860820859 53.5004557568433 -7.33544892784694 8.4971454218717e-13 CLN5 other 3.0189395743976e-22 1.24916534846936e-08 0.0245155191748563 4.75153415921312 -7.33544892784694 0.659511066851418 598.037561863218 1413.08439524644 0.423214327378458 0.672315911723161 -1167.36316073743 2487.19666825131 -0.469348956453119 0.639019254577255 OLFM4 other 1 1 1 0.423214327378458 -0.469348956453119 9.7953059454272e-07 108.882246818467 103.526105871251 1.05173710439642 0.293394102794924 2395.91831057481 454.640990460401 5.26991265822411 1.9812852646902e-07 MSLN other 0.00654130531035629 0.00258617165600012 1 1.05173710439642 5.26991265822411 4.56505132477434e-26 378.775348488853 39.0162703929151 9.70813828883126 1.17652179918871e-20 -620.645907685113 196.221941443455 -3.1629791404544 0.00164878473794258 MGRN1 other 5.98889083297145e-22 1 1.62771790917758e-16 9.70813828883126 -3.1629791404544 1.07124735728193e-24 209.531368315485 23.5857037949692 8.88382937973543 1.03413920541135e-17 -603.34213713437 143.211673151469 -4.2129396567851 2.96787583482401e-05 ZNF629 other 1.37869534882185e-20 0.347360187707803 1.38450556820472e-13 8.88382937973543 -4.2129396567851 3.38764012731266e-14 65.0033321281241 18.2118212614001 3.56929332849858 0.000391772712556833 -151.86584643277 39.9892591576155 -3.79766591409455 0.000163655457650645 TRADD other 3.39373787954182e-10 1 1 3.56929332849858 -3.79766591409455 1.88790715147855e-06 59.3801536345075 23.3190703930731 2.54642027463266 0.0111780016645586 -111.119244387071 51.2012051407155 -2.17024665887616 0.0304516923177779 HSF4 other 0.0123072667204886 1 1 2.54642027463266 -2.17024665887616 0.328190939851015 31.4953720116035 32.633965370908 0.965110174434408 0.334928954863704 265.117401955797 198.536720882746 1.3353570099124 0.182331666782808 CORO1A other 1 1 1 0.965110174434408 1.3353570099124 4.50838476517732e-24 356.378867968893 40.223992744232 8.85985810098369 1.20649740056635e-17 -990.542461975528 241.683424831576 -4.09851218661692 4.8087379593168e-05 MAPK3 other 5.74368219083591e-20 0.555505409060276 1.61296637481716e-13 8.85985810098369 -4.09851218661692 0.000171246128261029 90.3657212461616 22.6399604702005 3.99142575205041 7.48989725004269e-05 -43.6613590032061 136.23653604136 -0.320482010713713 0.748728805338102 GDPD3 other 0.901439619166054 1 0.626155410103569 3.99142575205041 -0.320482010713713 2.03904463621626e-23 151.39728688445 43.3087269946153 3.49576857577167 0.000513345011538622 -583.273436754158 94.3611822354617 -6.18128580986514 1.29095083749196e-09 ELMO3 other 2.57082747734147e-19 1.80423289047876e-05 1 3.49576857577167 -6.18128580986514 3.89153193643425e-34 242.825074137116 46.6779442898408 5.20213727985372 2.89866699715604e-07 -925.625685121985 124.734683153095 -7.42075629426905 5.1681183781541e-13 PHKB other 5.51702482628284e-30 7.61573924204788e-09 0.00288562299566884 5.20213727985372 -7.42075629426905 4.5498511615418e-35 151.990935258703 12.1262941060102 12.533997108265 7.58725665245946e-32 -106.761925138364 64.8452230889206 -1.64641156360838 0.100255535461263 LYRM1 other 6.49468336527388e-31 1 1.12238287659833e-27 12.533997108265 -1.64641156360838 5.86669479940783e-60 566.098364360555 58.1315327714905 9.73823220154601 1.00700072278662e-20 -960.836226948803 129.997042822586 -7.39121603143011 5.71984756462762e-13 NUTF2 essential 9.0135898898102e-56 8.42419149318356e-09 1.39368900033668e-16 9.73823220154601 -7.39121603143011 4.33525786378229e-50 316.173636772561 33.1032642358701 9.55113171075018 4.39118555548875e-20 -339.614691919161 70.6333432892042 -4.80813559296815 1.97632929464721e-06 NUP93 essential 6.55794457054348e-46 0.0247535244154563 6.04490603568581e-16 9.55113171075018 -4.80813559296815 8.83451285527592e-25 103.841184778137 18.1373541847906 5.72526641538571 1.73255224560001e-08 -176.000873320106 40.5597839285768 -4.33929514097099 1.71274948319439e-05 CENPT essential 1.13797360088809e-20 0.203952854556315 0.000183702514600969 5.72526641538571 -4.33929514097099 2.96941642932942e-12 16.9948428357806 3.60449984041123 4.71489626528648 3.09726676005064e-06 -15.4787748398697 8.07881916924875 -1.91596995991545 0.0559075864342385 TSNAXIP1 other 2.75532150477477e-08 1 0.0289036934047925 4.71489626528648 -1.91596995991545 5.89901983750225e-08 168.989038897803 56.0076129994334 3.01725122439181 0.00267036535126519 -275.368169815948 123.820274146199 -2.22393442200598 0.0265633887539751 NFAT5 other 0.000434639781627166 1 1 3.01725122439181 -2.22393442200598 1.8758242429647e-19 384.22940230402 105.56138783175 3.63986690774118 0.000301406409972976 -1534.6638991856 281.898791416208 -5.44402440136665 8.20594490081995e-08 LONP2 other 2.19640260608737e-15 0.00108966742337988 1 3.63986690774118 -5.44402440136665 5.1528394468386e-24 53.620381751409 25.1488428863975 2.1321212269536 0.0334855619454586 -517.79351047999 67.2365878521791 -7.70106763327087 7.33291530396272e-14 N4BP1 other 6.55904933188085e-20 1.0904778348523e-09 1 2.1321212269536 -7.70106763327087 0.411645142527873 11.4464193485836 9.14955284536014 1.25103592951958 0.211500632242526 26.4333408824869 24.4198148977915 1.08245459652839 0.279567164379342 CBLN1 other 1 1 1 1.25103592951958 1.08245459652839 1.10064821735212e-37 227.04353614801 33.7117716483713 6.7348443895555 4.18285948850183e-11 -408.678308116179 70.8900028254251 -5.76496391349563 1.36984482967535e-08 ARL2BP other 1.59461913729976e-33 0.000186559167353487 4.86843015866728e-07 6.7348443895555 -5.76496391349563 1.3855280378104e-27 233.714903487908 41.4685993080017 5.63594882363945 2.7977822971327e-08 -417.140691714511 87.2012646731572 -4.78365415086598 2.21995403228518e-06 PLLP other 1.85078835290713e-23 0.0277472054495325 0.000294102875074589 5.63594882363945 -4.78365415086598 0.0818138475600403 4.11280485531293 11.3798914380219 0.361409849796232 0.717943348078969 60.9157313841452 29.8909114903901 2.03793488879486 0.0420739489249526 ZNF423 other 1 1 1 0.361409849796232 2.03793488879486 0.123019117381111 -19.5141865670857 14.8731054107261 -1.31204520025876 0.190057235899304 -66.2676229508878 32.3494734443778 -2.04849154855115 0.0409903430010765 CCL22 other 1 1 1 -1.31204520025876 -2.04849154855115 4.99969160806407e-51 72.7660212240319 6.97680244752665 10.4297092789016 2.4111991091938e-23 -75.6410256041692 15.6633592375592 -4.82917006862674 1.78381971832952e-06 DHODH essential 7.57603269369949e-47 0.0223887212847538 3.41570465808394e-19 10.4297092789016 -4.82917006862674 0.0457418927391922 -4.4694457490722 4.1045629913531 -1.08889685905364 0.276680631983686 -21.8319949884487 8.92755398571944 -2.4454621079157 0.0147820271375536 CCL17 other 1 1 1 -1.08889685905364 -2.4454621079157 7.55054305775915e-25 218.620320512918 36.1718344675324 6.04393787959941 2.85077384767154e-09 -316.824185785077 79.7186013539521 -3.97428179125186 8.04511022710563e-05 CTCF other 9.74171065312086e-21 0.91320046187876 3.11475550596593e-05 6.04393787959941 -3.97428179125186 1.61873025714398e-30 73.4481107626001 13.7276389486207 5.35038188558857 1.3149491746633e-07 -181.733999139427 30.1902352653294 -6.01962845079685 3.29288534741495e-09 ACD other 2.22510661147012e-26 4.55801189789177e-05 0.00133309547327365 5.35038188558857 -6.01962845079685 3.53437201262265e-87 400.640475078053 28.2370731544615 14.1884561790977 4.10326457246633e-39 -447.758564852014 61.5963314764126 -7.26924078300794 1.26120342395473e-12 POLR2C essential 5.50725847006862e-83 1.85094214499596e-08 6.19141591339445e-35 14.1884561790977 -7.26924078300794 1.49590835932785e-14 18.8510973390128 8.17281166135973 2.30656206457552 0.0214692082211844 -90.5139937488068 17.9738925068735 -5.03585930060463 6.55862856979241e-07 PARD6A other 1.5180478030459e-10 0.00839701215790522 1 2.30656206457552 -5.03585930060463 1.16362198761827e-20 28.952833708049 6.74357824175903 4.29339330991387 2.08563673556569e-05 -71.5857857757018 14.8682562152896 -4.8146725977245 1.91619701921856e-06 ZNF821 other 1.39553184975059e-16 0.0240176134388854 0.183077192647956 4.29339330991387 -4.8146725977245 1.28495076590724e-21 653.02583335652 78.5021511334107 8.31857247130379 7.19493543062462e-16 32.2924877431431 170.668836098147 0.189211390207012 0.849997712108291 MMP15 other 1.57046682609183e-17 1 9.34334315020913e-12 8.31857247130379 0.189211390207012 3.74574457917601e-40 368.032830473762 38.1930103370192 9.6361304653967 2.14477989318206e-20 -255.599360844653 83.034114698665 -3.07824514986685 0.00218720724524217 USB1 other 5.48901410632453e-36 1 2.96108312052716e-16 9.6361304653967 -3.07824514986685 4.18235452210153e-76 304.070752380591 28.09098039403 10.8244976898426 7.37556264329454e-25 -548.074298766501 61.4751333556082 -8.91538202277851 7.38453455797268e-18 CYB5B other 6.49143245375379e-72 1.12865226184054e-13 1.05551676988188e-20 10.8244976898426 -8.91538202277851 9.09110210883728e-28 153.35680744765 19.9107983593449 7.70219278403135 6.36460902283258e-14 -110.842193393694 43.2873842654233 -2.5606119490623 0.0107175866372129 CCDC113 other 1.21684401726787e-23 1 7.96276234846584e-10 7.70219278403135 -2.5606119490623 6.60843293444233e-26 22.74480380649 2.99220591082933 7.60134980155358 1.29213732251628e-13 -14.3195975441531 6.50525231212285 -2.20123630215969 0.0281385154162291 PRSS54 other 8.65440377094567e-22 1 1.60483455456522e-09 7.60134980155358 -2.20123630215969 2.4324249237147e-11 360.262971937403 65.7426752786907 5.47989521890017 6.52279387864997e-08 -761.770103777019 300.925475112266 -2.53142444484909 0.0116410486103809 NME3 other 2.16412845462897e-07 1 0.000673739379725756 5.47989521890017 -2.53142444484909 1.12937233929819e-06 124.908515449983 25.5496280470408 4.88885846870286 1.33823402801588e-06 72.2368643558615 55.6452805149932 1.29816695481296 0.19478209713037 NDRG4 other 0.00749903233293996 1 0.0127854879036637 4.88885846870286 1.29816695481296 9.97352580075756e-99 605.954023503719 40.3403203888941 15.0210513367797 6.14969871682342e-43 -760.171633683723 87.9879554601986 -8.63949650503684 6.24633093583153e-17 PSMD7 essential 1.55716658327228e-94 9.49942008721259e-13 9.34385223034151e-39 15.0210513367797 -8.63949650503684 1.09430357664857e-84 351.347782901354 25.4312338971002 13.8156010959978 2.15873426231984e-37 -392.298687222108 54.7296642312152 -7.16793520904445 2.51475686568865e-12 SETD6 other 1.70426839027249e-80 3.68110109999504e-08 3.24349822913556e-33 13.8156010959978 -7.16793520904445 1.68895588320874e-44 113.573627897131 15.0096988308834 7.56668266144326 1.66224009086047e-13 -206.486929166297 32.3018450677527 -6.39241903158141 3.53435334941978e-10 SLC38A7 other 2.51721984833431e-40 4.99969624808922e-06 2.05968169658521e-09 7.56668266144326 -6.39241903158141 3.37950358006162e-49 227.926177735217 24.6411384771687 9.24982333695345 5.43312429826194e-19 -304.307067797172 53.8118128276619 -5.65502353120397 2.54600266691636e-08 VAC14 other 5.09899500159697e-45 0.000343583059900362 7.38904904563624e-15 9.24982333695345 -5.65502353120397 5.58001292784354e-06 177.574081839985 52.8838527182797 3.35781288072844 0.000840682440377515 -112.090481511237 117.192935075157 -0.956461082226094 0.339264966130633 HAS3 other 0.0346630403077641 1 1 3.35781288072844 -0.956461082226094 9.17092058532087e-27 48.8232582662632 7.74991773629301 6.29984213092004 6.16948399313506e-10 -69.9840604180337 17.2089192525329 -4.06673187264407 5.47524514829475e-05 TANGO6 essential 1.21358792105551e-22 0.629926954311311 6.92339493709616e-06 6.29984213092004 -4.06673187264407 2.54195605895299e-83 313.664415353484 26.1436135025178 11.9977452743201 1.45024536879875e-29 -520.177508036911 57.1127966172333 -9.10789768400085 1.62750295740897e-18 COG4 essential 3.95731719257801e-79 2.4939855319335e-14 2.12750995602776e-25 11.9977452743201 -9.10789768400085 1.43010603053495e-06 53.6965570585335 25.4666385196114 2.1085058798468 0.0354489498752629 -149.888390712867 57.0025381739628 -2.62950379955769 0.00879562744346827 SMPD3 other 0.0094143879990116 1 1 2.1085058798468 -2.62950379955769 7.70625087870634e-47 188.072808210152 19.3905699940992 9.69918925887093 1.29978702469235e-20 -200.607327985141 43.2784191518105 -4.63527392905592 4.47477178603252e-06 SLC7A6OS essential 1.15593763180595e-42 0.0551157640885626 1.79786541255446e-16 9.69918925887093 -4.63527392905592 5.79900621886993e-38 246.479505223668 27.2083906151029 9.05895202367656 2.4043142147477e-18 -209.427378796237 60.727257313475 -3.44865531659317 0.000607362306444791 SLC7A6 other 8.41493792420216e-34 1 3.24534332706645e-14 9.05895202367656 -3.44865531659317 1.50837713441618e-24 108.720848625297 18.304564815639 5.93954839791703 5.12797637292605e-09 -162.89325090739 40.7706655537676 -3.99535422576238 7.35797056667093e-05 PLA2G15 other 1.93675624059037e-20 0.837704949015485 5.55052162605516e-05 5.93954839791703 -3.99535422576238 1.31538022837043e-12 29.0204239873503 12.2721168659773 2.36474475465642 0.0183912973118876 -117.669471353259 26.8079387950113 -4.38935168619363 1.36530856818096e-05 FA2H other 1.23777279489658e-08 0.163563966468079 1 2.36474475465642 -4.38935168619363 2.03233240323509e-52 136.936442769831 15.6340896380905 8.75883699913059 2.49118255610902e-17 -231.807912209034 34.2500032088396 -6.76811359098521 3.37952239023021e-11 WDR59 other 3.08711292051411e-48 4.86853995536563e-07 3.31700957345916e-13 8.75883699913059 -6.76811359098521 4.09460874160163e-19 264.50682691957 40.1530242338015 6.58746961074239 1.05402975936047e-10 -161.454643754801 90.9696398895264 -1.77481898302413 0.076484865363251 MON1B other 4.7517934446287e-15 1 1.21371526790358e-06 6.58746961074239 -1.77481898302413 8.3196046588862e-52 146.856899192667 15.7088635105173 9.34866479006227 2.2372074013164e-19 -197.817334207214 33.2892178157524 -5.94238456734203 4.99902044699542e-09 CMC2 other 1.26225041884621e-47 6.89114968618319e-05 3.05781507611926e-15 9.34866479006227 -5.94238456734203 1.24147370634989e-16 201.734066380634 24.2297819983234 8.32587211864282 7.30550321456729e-16 7.44596847411871 107.2868458672 0.0694024361880801 0.944695715858417 AXIN1 ts 1.34886118194915e-12 1 9.48546537379418e-12 8.32587211864282 0.0694024361880801 4.89276790764962e-18 333.096198904784 40.1547514391722 8.29531218514375 8.6219103340021e-16 -202.725840165285 182.631240431651 -1.11002827164805 0.267479073656104 HCFC1R1 other 5.52491352131795e-14 1 1.11791689390671e-11 8.29531218514375 -1.11002827164805 9.08599072103746e-23 320.501641515094 35.169732280674 9.11299633893465 1.69652562089234e-18 -294.50117716563 156.40548243232 -1.8829338497969 0.0602630213249434 NPRL3 other 1.135021960872e-18 1 2.29421159713271e-14 9.11299633893465 -1.8829338497969 4.66148275758906e-21 35.7580696566816 9.15356244065968 3.9064648204994 0.000105381832135555 -99.2657477214655 19.5140035015924 -5.08689811977154 5.00964654517626e-07 MLYCD other 5.64039413668277e-17 0.0064459122096783 0.868873205957649 3.9064648204994 -5.08689811977154 7.94752893182794e-14 197.404290373048 31.9370297137959 6.18104727152427 1.28114582525219e-09 -370.890231371943 142.029131753911 -2.61136730748008 0.00927655299751004 MPG other 7.85056907885964e-10 1 1.42002203270953e-05 6.18104727152427 -2.61136730748008 5.5394369463938e-30 121.487817474414 24.0455526404814 5.05240279942185 5.95629145528942e-07 -309.749031815049 52.1973824648446 -5.93418706433541 5.24466946324449e-09 HSDL1 other 7.57684185527745e-26 7.22505665256561e-05 0.00580797979805271 5.05240279942185 -5.93418706433541 1.84742852948695e-18 108.514693203999 26.0501371865915 4.1656092797797 3.60803168689694e-05 -236.54200031879 56.5488759738883 -4.18296555404592 3.3511292218843e-05 TAF1C essential 2.10883966640935e-14 0.390674644687271 0.31050720697435 4.1656092797797 -4.18296555404592 3.1294349631899e-16 47.0402727287536 6.31404573782781 7.45010009144099 3.6956106899362e-13 -61.4729645906248 30.7674444260517 -1.99798734465492 0.0462163141939395 NAGPA other 3.36101315046595e-12 1 4.53931861044864e-09 7.45010009144099 -1.99798734465492 0.00292316287623947 22.7819610647593 12.8583496890845 1.77176399892896 0.0769893878430272 -35.2940613575654 27.9055102093036 -1.26477033004752 0.206491265412799 WFDC1 other 1 1 1 1.77176399892896 -1.26477033004752 0.854925333773587 0.120162974443349 3.34735802707535 0.0358978554045915 0.971376974185253 9.0486897472519 16.5314701016993 0.547361468253313 0.584354902428116 SEC14L5 other 1 1 1 0.0358978554045915 0.547361468253313 9.79168091622398e-07 622.830394266243 203.254313558291 3.06429115014882 0.0022892111170325 -675.339508887794 430.098816636754 -1.57019615670824 0.116946672144004 COTL1 other 0.006539863683946 1 1 3.06429115014882 -1.57019615670824 3.45775866099228e-64 429.718262368511 38.4764854145116 11.1683345747177 3.10510555700294e-26 -489.822036000685 82.6530113541729 -5.92624549275972 5.48300234951115e-09 USP10 essential 5.33532161391109e-60 7.55064253551181e-05 4.47973578708815e-22 11.1683345747177 -5.92624549275972 0.00279540846162445 -410.842234138849 124.279583370458 -3.30579024323079 0.0010090650412891 -334.536633818801 266.970376965257 -1.25308522099565 0.210709097479607 CRISPLD2 other 1 1 1 -3.30579024323079 -1.25308522099565 7.5908362995011e-25 350.144196174214 37.0327528131193 9.4549869933021 9.63663208092589e-20 -401.290000261198 169.430963949337 -2.36845728140454 0.0182115895498629 TSC2 ts 9.79217882635642e-21 1 1.32147135725737e-15 9.4549869933021 -2.36845728140454 6.44723018734823e-27 85.206520461538 8.73675522201459 9.75265053172572 8.2075523786462e-21 -152.089008097715 44.1510741912617 -3.44474083323245 0.000615864307420523 ZNF500 other 8.54451416729261e-23 1 1.13740260863279e-16 9.75265053172572 -3.44474083323245 1.02971986065214e-14 519.471926162874 85.5877423440989 6.06946639712002 2.45502137169257e-09 -1191.36963381403 376.442383748191 -3.1648126917902 0.0016414635372899 NME4 other 1.05072614580944e-10 1 2.68849390414053e-05 6.06946639712002 -3.1648126917902 3.21104540165197e-12 294.366621297673 39.5769035854783 7.4378386035658 4.03962176108754e-13 308.596695012374 200.999261537476 1.53531258101083 0.125291660104477 ABCC1 other 2.97696019187154e-08 1 4.95459608997387e-09 7.4378386035658 1.53531258101083 9.32313830841651e-17 491.35072149688 56.2665778117866 8.73255030971428 3.1345617452246e-17 227.927746988273 286.849345596626 0.794590437409575 0.427201500937253 NOMO3 other 1.01650176976665e-12 1 4.16708638410158e-13 8.73255030971428 0.794590437409575 1.8786335480682e-10 50.450536312436 8.38930569594771 6.01367242307133 3.35116069457599e-09 -37.2921051961057 37.0002778190378 -1.00788716718548 0.313961714071175 LMF1 other 1.60153509972814e-06 1 3.65209492494891e-05 6.01367242307133 -1.00788716718548 0.540196393621271 -1.22541524380708 1.23897610397157 -0.989054784736353 0.323076041885194 -0.565423986631025 2.61681237436631 -0.216073568044002 0.829011397723037 FOXF1 other 1 1 1 -0.989054784736353 -0.216073568044002 1.61252162765439e-20 200.390433468233 23.5172599760995 8.52099409845744 1.61013782504006e-16 -202.199418586448 103.277432087955 -1.95782771219803 0.0507686436678879 NARFL essential 1.92905962316295e-16 1 2.11459400562511e-12 8.52099409845744 -1.95782771219803 2.51795475901917e-45 76.8755838174803 8.98487883485546 8.55610690254979 1.19835550725596e-16 -97.912673171791 18.9902907350071 -5.15593334183647 3.54094576378579e-07 MTHFSD other 3.76383877378185e-41 0.00458198381833882 1.57727551865029e-12 8.55610690254979 -5.15593334183647 1.15529737860789e-21 433.223863331642 50.3657689119696 8.60155364824947 8.49678734832645e-17 -562.341677601162 228.438021346077 -2.46168161625437 0.01413904757116 CLCN7 other 1.41373740220247e-17 1 1.12191580147302e-12 8.60155364824947 -2.46168161625437 9.50576565237755e-09 125.921637655013 24.6003562105775 5.11869163914261 4.29506067569358e-07 -163.993844687783 108.033912983889 -1.51798486381068 0.129607788363753 HAGHL other 7.3593637680707e-05 1 0.00423192328376089 5.11869163914261 -1.51798486381068 1.19021351172954e-09 97.8946347684955 18.378575338338 5.32656274854373 1.47658187840268e-07 -140.293106191354 80.3904100045791 -1.74514729037161 0.0815333720676849 FAM173A other 9.7026205476192e-06 1 0.00149193832993806 5.32656274854373 -1.74514729037161 9.20676071689504e-12 2057.80180998625 376.803396270493 5.46120823313662 7.23008685433574e-08 -287.845661110976 803.026277290695 -0.358451110818104 0.720146096006898 SLC7A5 essential 8.36342143522746e-08 1 0.000744915848602211 5.46120823313662 -0.358451110818104 4.32583246494557e-14 613.920241688792 88.7164384585115 6.92002803940212 1.2956727335013e-11 -603.637970345983 388.057873395028 -1.55553594381399 0.120409809973203 METRN other 4.31285496755073e-10 1 1.53252170918534e-07 6.92002803940212 -1.55553594381399 1.43455322443677e-13 21.0952930910428 12.0436784680758 1.75156561568461 0.080414118544426 -126.49056568812 25.7328855910857 -4.91552201716306 1.17510903123382e-06 FBXO31 other 1.40284959817672e-09 0.0148733550083264 1 1.75156561568461 -4.91552201716306 3.12014158624846e-19 757.958145819346 97.7175342244357 7.75662374040756 4.45264583306484e-14 -1147.99132100164 427.278412136528 -2.68675245084656 0.00743985632426298 STUB1 other 3.63059674975871e-15 1 5.59163263716283e-10 7.75662374040756 -2.68675245084656 4.81278743826966e-07 41.6555763862991 9.37173436589335 4.44480976092287 1.0703657849822e-05 -60.4570473044082 40.9787231186898 -1.47532774823905 0.140713803051833 RHBDL1 other 0.00329964706767768 1 0.0962151804120503 4.44480976092287 -1.47532774823905 1.20556959313724e-31 101.316471231579 9.95390177830289 10.1785685139495 2.19307677102133e-22 -228.557883784752 51.7857317111148 -4.41353006383603 1.22765790974391e-05 NUBP1 essential 1.67501839270488e-27 0.147417161802049 3.07886047883684e-18 10.1785685139495 -4.41353006383603 2.90383876393683e-36 561.261496315029 43.1275480819796 13.0139903907393 7.17303372577303e-34 -13.3251539501408 196.336948863052 -0.0678688042536265 0.94591519389047 UBE2I essential 4.17601052641755e-32 1 1.06842337345389e-29 13.0139903907393 -0.0678688042536265 0.0345572751099451 24.4513615512045 9.45609467573811 2.58577799711972 0.00997479424214218 20.1873829420676 50.5503476952775 0.39935200967873 0.689790580997006 ZP2 other 1 1 1 2.58577799711972 0.39935200967873 0.0047136358692643 0.394801208662265 0.414550441148059 0.952359880667114 0.341337447092718 6.44978225996904 1.96126997147631 3.2885744205394 0.0010720473737531 MEFV other 1 1 1 0.952359880667114 3.2885744205394 0.247009424554995 29.6463891335859 17.7999209867109 1.66553487263901 0.0963818105215255 25.9384686694589 95.1547362501917 0.272592512907171 0.785269906366396 CRYM other 1 1 1 1.66553487263901 0.272592512907171 8.12391529555212e-11 127.344644273048 19.9410079211991 6.38606858671716 3.72984432324023e-10 -34.6832207473926 87.8058350379054 -0.394999042289387 0.69300281210674 CAPN15 other 7.04180977818458e-07 1 4.22218377390794e-06 6.38606858671716 -0.394999042289387 5.13389069546252e-32 927.17270976141 87.9287733924241 10.5445882387493 8.99114452801528e-24 -1782.11380619482 456.830705729615 -3.90103770137029 0.000107821518683095 GSPT1 essential 7.1561302404052e-28 1 1.27782146032153e-19 10.5445882387493 -3.90103770137029 6.43285821165415e-32 61.0782097909374 5.95583225387648 10.2551930926502 1.11363718937588e-22 -107.41893814828 27.3713924186892 -3.92449666078859 9.80566980641916e-05 ZNF174 other 8.96032820301307e-28 1 1.56777843520336e-18 10.2551930926502 -3.92449666078859 4.25413255415316e-22 143.166865649999 15.3568918430811 9.3226459568055 2.839969613942e-19 -91.9387981541135 70.8663679818938 -1.29735445419756 0.195060169146661 CLUAP1 other 5.25215205135749e-18 1 3.87400255037828e-15 9.3226459568055 -1.29735445419756 6.1296524263469e-25 393.940228769279 41.6051135870335 9.46855313698875 8.76975261597924e-20 -743.841422418054 227.816075988119 -3.26509628081228 0.00116362403505566 UBFD1 other 7.91522017814176e-21 1 1.20294696633387e-15 9.46855313698875 -3.26509628081228 0.178981335460742 16.6708073504681 12.6502533722045 1.31782398818175 0.188118274518051 96.4757391027291 57.5822129439083 1.67544340813556 0.0944229673511871 PRSS33 other 1 1 1 1.31782398818175 1.67544340813556 1.82571702191366e-34 263.203771221365 22.7711332229373 11.5586593185552 9.24655052871743e-28 -456.309075522419 124.172299909004 -3.67480570027947 0.000261826563447698 EARS2 essential 2.59507417494807e-30 1 1.34546556743367e-23 11.5586593185552 -3.67480570027947 1.45681729265482e-11 709.154107739397 113.817146892587 6.23064386255132 9.32268502990365e-10 -708.832117485876 518.079993831374 -1.36819048395177 0.171818327794879 ELOB other 1.30967874609669e-07 1 1.03910647343306e-05 6.23064386255132 -1.36819048395177 1.81798336538809e-12 434.261362080042 63.1331738113079 6.87849724422155 1.68239401058982e-11 -431.244743281648 344.268830011867 -1.25263952378954 0.210880120472566 GGA2 other 1.70108703499363e-08 1 1.98286958088116e-07 6.87849724422155 -1.25263952378954 1.82769704022565e-08 112.891417783217 21.2314071386519 5.31718962600918 1.54318112308245e-07 -146.685257945077 109.593141262314 -1.33845290184704 0.181310020079638 CPPED1 other 0.000139215683553988 1 0.00155768702563942 5.31718962600918 -1.33845290184704 8.29445647105375e-05 75.6468390316722 17.3284022526557 4.36548262954126 1.51956806632226e-05 128.880343483408 95.6982019602803 1.34673735601532 0.178627692522764 USP31 other 0.455780383084404 1 0.134876861566764 4.36548262954126 1.34673735601532 2.80242297868924e-32 255.990541150346 21.2907646950673 12.0235484641683 1.0756985256823e-29 -143.418498786194 107.016226038364 -1.34015657340393 0.180753910097757 HMOX2 other 3.91414417433526e-28 1 1.57934057540675e-25 12.0235484641683 -1.34015657340393 1.01913222516423e-43 399.60402279952 27.4210083012468 14.5729149858195 7.49796095221449e-41 -137.975775512442 136.801095238649 -1.00858677535983 0.313621246837166 DNAJA3 essential 1.51534770559669e-39 1 1.13504132894623e-36 14.5729149858195 -1.00858677535983 2.77596073319464e-20 151.511966419401 16.8508571557458 8.99135070809966 4.0532369248107e-18 -130.898959119915 84.3658741899897 -1.55156288459874 0.121349465607372 CORO7-PAM16 other 3.30589163716149e-16 1 5.45525157710273e-14 8.99135070809966 -1.55156288459874 6.30666221525072e-34 227.877736319132 19.8188697504355 11.4980187663893 1.50358857387531e-27 -341.400289171968 103.863997796154 -3.28699353400597 0.00107772096640744 BFAR other 8.92581903324435e-30 1 2.18456383898344e-23 11.4980187663893 -3.28699353400597 0.0423256565616184 -5.60676854655109 2.30177712498416 -2.43584336888815 0.0151958471809927 -11.5607936070205 6.06690244508415 -1.90555126139995 0.0572661017628807 SALL1 other 1 1 1 -2.43584336888815 -1.90555126139995 0.013772345903554 91.2172207683929 55.4763388611812 1.64425451716715 0.100723412276854 -101.409304311989 121.595013032445 -0.833992297734531 0.404665341928999 TOX3 other 1 1 1 1.64425451716715 -0.833992297734531 6.61771997316829e-08 18.0622905813844 3.44214842118246 5.24738865710491 2.22596218500999e-07 -23.7558168285174 20.7216278521864 -1.14642618803768 0.252130378244195 RRN3P2 other 0.000485012696833504 1 0.00222974632072451 5.24738865710491 -1.14642618803768 1.82841482032481e-18 418.37468456804 72.0842323893061 5.80396947710449 1.11583540904501e-08 -337.950691758492 161.309593983011 -2.09504396740398 0.036641117133317 RBL2 ts 2.08750120036483e-14 1 0.000119227013456459 5.80396947710449 -2.09504396740398 0.173119444630907 54.4601119144396 29.0329462800192 1.87580383296888 0.061222472858969 81.4669711239957 146.274531717437 0.556945697706065 0.577795710642842 XYLT1 other 1 1 1 1.87580383296888 0.556945697706065 1.54121321560769e-08 299.830549583102 58.0109399317525 5.16851735096587 3.38366110516542e-07 -650.524513025177 341.932785729394 -1.90249236158361 0.0576654096153358 PYCARD other 0.000117825750333208 1 0.00335523835188203 5.16851735096587 -1.90249236158361 1.92307838950171e-36 80.4672504761562 9.8318442043125 8.184349630038 2.04131563835565e-15 -79.8528782173872 22.0087860394751 -3.62822729405259 0.000312942883452066 RPGRIP1L other 2.76692518681506e-32 1 2.62921454220208e-11 8.184349630038 -3.62822729405259 4.66606795213661e-13 827.305881896321 122.51149467673 6.75288375249464 3.786452705348e-11 -1570.4409260071 757.508188526216 -2.07316693046249 0.0386348328296394 MAZ other 4.46309399621867e-09 1 4.41348927335363e-07 6.75288375249464 -2.07316693046249 1.7358873049935e-28 220.064217398451 20.2865689472756 10.847779038949 7.45136838704643e-25 -295.367113780702 120.708624894052 -2.44694290934016 0.0147373024288508 STX4 other 2.34067044205324e-24 1 1.06629081618634e-20 10.847779038949 -2.44694290934016 1.04276785867669e-33 457.692397282134 39.5835915473441 11.5626798729143 9.55442210166262e-28 -868.728217798457 244.55498099766 -3.55228183966847 0.000415764735745504 CDIPT essential 1.47353526109603e-29 1 1.38988178312886e-23 11.5626798729143 -3.55228183966847 3.67451639456352e-39 377.365298265016 28.5083998614096 13.2369862952511 1.18968562755313e-34 -439.915327690199 168.437438269141 -2.61174316239167 0.00927001340063888 BCKDK other 5.36038451638927e-35 1 1.77608167337407e-30 13.2369862952511 -2.61174316239167 1.35016556111148e-40 254.854285486824 19.0107003973395 13.4058335653163 2.25455735410784e-35 -332.226211109016 112.145573673728 -2.96245496122372 0.00319272179740261 KAT8 essential 1.98217806026776e-36 1 3.37259234600992e-31 13.4058335653163 -2.96245496122372 1.35211535272559e-18 629.385642975056 68.389751974799 9.20292331527945 7.40449082495453e-19 194.371585853895 358.213438888695 0.542613885333014 0.587617491110845 NOMO1 other 1.54803686733553e-14 1 1.00567794384532e-14 9.20292331527945 0.542613885333014 0.00742587757364073 4.8360581468642 5.68803469374255 0.850216007329277 0.395580422518103 102.264022120233 32.5400874144305 3.14270889373463 0.00176545321512339 IL21R other 1 1 1 0.850216007329277 3.14270889373463 1.52769219327954e-15 173.254709837562 24.1036204727291 7.18791229033755 2.16901025649384e-12 -315.718261269805 127.89839014865 -2.46850848476561 0.0138723803148868 SYT17 other 1.60468787982083e-11 1 2.61712777548547e-08 7.18791229033755 -2.46850848476561 8.27235801578617e-06 288.334033787693 86.7851863221345 3.32238767936082 0.000952141301491875 -1175.53030360382 460.076883926681 -2.55507360763457 0.0108860361249163 TMC5 other 0.0506268310566114 1 1 3.32238767936082 -2.55507360763457 9.74428880307085e-10 157.196572485174 26.0840663612444 6.02653628878723 3.08050054233002e-09 -128.935496576243 141.435302451505 -0.91162174040991 0.362369444387025 CCP110 other 7.9766748141938e-06 1 3.36205829189899e-05 6.02653628878723 -0.91162174040991 2.35512703529023e-28 302.189655757071 29.1853998564153 10.3541379334793 4.6356645528174e-23 -481.179440186182 158.20926017059 -3.04141135397099 0.00246779910405012 C16orf62 other 3.17141406572183e-24 1 6.54833974730986e-19 10.3541379334793 -3.04141135397099 0.0793225783892677 7.64546269892586 6.28919448119511 1.21565054503976 0.224646320960673 -10.8627473343489 14.5646252448373 -0.745830884883184 0.456092320903497 SLC6A2 other 1 1 1 1.21565054503976 -0.745830884883184 1.86525324808142e-47 764.030151046096 53.1732710810967 14.3686881681746 1.01431948487197e-39 -1260.00893536693 322.849428446196 -3.90277579685082 0.00010747545792265 RNF40 essential 2.80254300524233e-43 1 1.5322310138476e-35 14.3686881681746 -3.90277579685082 1.45712144125628e-38 263.15014011347 19.2534111003234 13.6677152293835 8.52206346924497e-37 -53.2632636479258 104.580431572169 -0.509304301456911 0.610744333923502 KNOP1 other 2.12011169702789e-34 1 1.27890606482959e-32 13.6677152293835 -0.509304301456911 0.000184487473744779 23.0380044583421 13.0312972800988 1.76789800456209 0.0776405063228991 100.627711930432 24.108844138543 4.17389201042441 3.48794085303647e-05 AQP9 other 0.967636799791367 0.406100953519037 1 1.76789800456209 4.17389201042441 5.28160373132281e-41 519.609387543296 51.740148259617 10.0426729536229 7.14508457925027e-22 -857.080447931897 112.28478600719 -7.63309508268571 1.04560238649527e-13 AAGAB other 7.76765460765646e-37 1.55240586322952e-09 9.98597020796017e-18 10.0426729536229 -7.63309508268571 2.35164547032808e-22 16.5848201901431 3.92279616785406 4.22780574888134 2.77118700594117e-05 -67.6863278387421 8.51312458648487 -7.95082077692114 1.09019402184057e-14 IQCH other 2.91604038320682e-18 1.6322384894997e-10 0.240843862686347 4.22780574888134 -7.95082077692114 0.000392032079156618 71.5557128225679 27.7431051698711 2.57922508617662 0.0101651009560191 -133.717945207229 61.2475172290303 -2.18323862348903 0.0294472454128993 LACTB other 1 1 1 2.57922508617662 -2.18323862348903 0.176240979439617 -4.13779496857314 5.56003967832425 -0.744202417242505 0.457076543798269 -22.3409899090726 12.0538100058845 -1.85343803313359 0.0643628057891997 CORO2B other 1 1 1 -0.744202417242505 -1.85343803313359 4.47812588425927e-07 235.378429203365 43.7624429858614 5.37854866282055 1.12084798760886e-07 216.882759588344 84.9244768171719 2.55383097684848 0.010928519284868 CSK other 0.00308139842095881 1 0.00114091116658706 5.37854866282055 2.55383097684848 3.40464358993489e-07 398.445560987991 96.5453980316397 4.1270280004171 4.25572615979946e-05 -508.353577314377 213.831779274041 -2.37735279124665 0.0177846826999852 HERC1 other 0.00236758915244073 1 0.363822029401256 4.1270280004171 -2.37735279124665 1.70965511616751e-60 239.725958858125 14.097244424089 17.0051643886153 3.23389583158827e-52 -105.406901860715 31.984828460627 -3.29552812798322 0.00104710270052658 TRIP4 other 2.62910763764239e-56 1 4.96661721815326e-48 17.0051643886153 -3.29552812798322 1.27792859244338e-57 83.8589976703292 4.81783461531331 17.4059519195172 3.56948568092032e-54 -11.3471769879725 10.9593619175633 -1.03538664689846 0.300952675883818 MTFMT other 1.95727543218627e-53 1 5.49272456580018e-50 17.4059519195172 -1.03538664689846 0.0247890751511312 -11.8894910393961 20.1366765784324 -0.59043958883118 0.555143903066653 110.466241945659 45.8148100592624 2.41114700252535 0.0162365249574304 RASL12 other 1 1 1 -0.59043958883118 2.41114700252535 0.619340377222608 17.5633178339509 17.9979667971057 0.975850107511885 0.329582264135469 13.9552099286032 37.9766518619713 0.367468148043285 0.713415983785837 AP3B2 other 1 1 1 0.975850107511885 0.367468148043285 9.94931364306845e-42 347.775961629374 24.1909994624808 14.3762543655445 6.19755981164573e-40 -28.8890711508138 58.4388142695956 -0.494347318847708 0.621261210009449 ACSBG1 other 1.46792173489832e-37 1 9.36699189932135e-36 14.3762543655445 -0.494347318847708 0.629864063157999 1.24854072114567 6.81232456062211 0.183276752309002 0.854649795102288 -13.3529007250747 15.50254553708 -0.861336010472371 0.389436013828608 IGDCC4 other 1 1 1 0.183276752309002 -0.861336010472371 1.79069351178104e-50 2233.52584498576 150.887357873857 14.8026042503376 7.35110642548298e-42 -1375.57742195407 346.594130704462 -3.96884222810748 8.19827923044516e-05 RAB11A other 2.71146811553885e-46 0.92984883031709 1.11457475623173e-37 14.8026042503376 -3.96884222810748 1.74151418402367e-27 1320.66678375958 112.530050421207 11.7361254066468 1.66931797530654e-28 608.374650820906 272.307961509788 2.23414198926769 0.0258799841457575 CTSH other 2.32457313283479e-23 1 2.43753810754262e-24 11.7361254066468 2.23414198926769 1.59303778200933e-14 86.3510447027816 10.5248125396216 8.20452092402646 1.70483915783496e-15 70.3256965615825 30.5350939098846 2.30311053796423 0.0216517562035845 TTC23 other 1.61534031095746e-10 1 2.19958348143866e-11 8.20452092402646 2.30311053796423 2.18944984708024e-06 539.829793665334 104.613401825703 5.16023553621504 3.46635927080763e-07 351.562686070896 206.847162223253 1.69962537697979 0.0897751751202417 CD276 other 0.0141744983099975 1 0.00343516203737036 5.16023553621504 1.69962537697979 1.84630640322269e-10 52.2988115615989 75.236206238892 0.695128239129155 0.487271743054912 -976.178428831744 154.297270229321 -6.3266085484268 5.23754513969531e-10 FAH other 1.57434547002799e-06 7.38284362891451e-06 1 0.695128239129155 -6.3266085484268 0.351864257205522 78.5254455467647 54.5007947852411 1.44081285155918 0.150213929481965 58.9035492160706 110.515102837036 0.532990946069415 0.594257908275532 CEMIP other 1 1 1 1.44081285155918 0.532990946069415 7.95680792654145e-30 168.938768077909 21.680309433776 7.7922673840954 3.38915353849954e-14 -167.084699040356 36.8932000936775 -4.5288752023707 7.30018620647635e-06 RPAP1 essential 1.08721823508262e-25 0.088887067250056 4.26863888174017e-10 7.7922673840954 -4.5288752023707 7.36874803520362e-11 510.032247412441 78.559720679048 6.49228692520628 1.94071638677954e-10 -88.8897013217915 165.765122040435 -0.536238867547233 0.592017614565795 HOMER2 other 6.40270516778842e-07 1 2.21455146895414e-06 6.49228692520628 -0.536238867547233 4.53226591051458e-18 -3.06000004117853 51.3297605378432 -0.059614539579286 0.952486174611175 -705.056386573137 86.7536305368702 -8.12711101783214 3.39942187025975e-15 EHD4 other 5.12282015865463e-14 5.11307043505768e-11 1 -0.059614539579286 -8.12711101783214 1.95798889349599e-24 117.644519209049 117.031857246137 1.00523500162544 0.315253041252275 -1747.54122012553 196.519245737746 -8.89246859036703 9.95375299341464e-18 TMEM87A other 2.50916276701512e-20 1.52033623221415e-13 1 1.00523500162544 -8.89246859036703 0.0071589335912394 275.39554581624 250.844501429349 1.09787356010196 0.272768782439635 -831.052422262582 421.063278601407 -1.97369959456684 0.0489458660081808 ZNF106 other 1 1 1 1.09787356010196 -1.97369959456684 0.00616153039060177 20.2691079152085 7.24623302022649 2.79719239757141 0.00534013680910859 33.7054044440986 12.6488676643824 2.66469737358458 0.00793794558473099 CEP152 other 1 1 1 2.79719239757141 2.66469737358458 0.0891684964946621 18.1520149024167 15.6123526620824 1.16267005334196 0.245479819662114 -37.6361497533354 30.6604142375653 -1.22751602316003 0.220166524498995 ATP8B4 other 1 1 1 1.16267005334196 -1.22751602316003 0.000246235884390159 -7.77915929857908 8.37947410285354 -0.928358892586108 0.353636974107904 48.1758005817383 15.4948821723166 3.10914275087616 0.00197542058814693 OCA2 other 1 1 1 -0.928358892586108 3.10914275087616 4.15144404712327e-32 56.2098811428339 13.3280987713384 4.21739680258906 2.8995903942492e-05 -243.90098028478 26.1501411910494 -9.32694697527148 2.81786036931193e-19 DTWD1 other 5.79250987895109e-28 4.3271063831154e-15 0.251800429836601 4.21739680258906 -9.32694697527148 0.418422673865153 -3.56012691070975 16.5149045675221 -0.215570540910726 0.829406083598796 29.0937225518928 28.422899854031 1.02360148687526 0.306494060868282 TGM5 other 1 1 1 -0.215570540910726 1.02360148687526 0.280551000416853 -6.68645902923582 6.36638072552498 -1.05027633713886 0.29405914260742 -18.5067988422284 11.8438478327419 -1.56256641452848 0.118738276614344 FAM189A1 other 1 1 1 -1.05027633713886 -1.56256641452848 1.26135458044215e-13 214.656049791248 78.0381696877886 2.75065459184953 0.00614831927630631 -742.240529259999 145.796277308123 -5.09094294425202 4.93716238704468e-07 TJP1 other 1.23701043703962e-09 0.0063541279921265 1 2.75065459184953 -5.09094294425202 0.414668581246792 46.7213653619418 40.8437664364889 1.14390442993529 0.253168223828362 82.1744108054666 72.1173122365469 1.13945470590934 0.255016872656903 BMF other 1 1 1 1.14390442993529 1.13945470590934 1.30354255557962e-08 108.1881656565 28.0354394719086 3.85897876738848 0.000127653193178591 -185.362248420067 61.6215771690139 -3.00807374520229 0.00275187574864741 DMXL2 other 0.000100046891140736 1 1 3.85897876738848 -3.00807374520229 0.841146687947677 -14.6591013989909 31.5502059560263 -0.464627756136437 0.642385675855626 -35.1211171517994 69.3469939347877 -0.506454788578528 0.612744516096195 SCG3 other 1 1 1 -0.464627756136437 -0.506454788578528 8.94361408825403e-14 112.893715505419 31.684326972342 3.56307759366221 0.000398728993890768 -257.236211768557 55.6031821136972 -4.62628579858184 4.65800542523313e-06 DNAJC17 essential 8.81035423833905e-10 0.0573167567574937 1 3.56307759366221 -4.62628579858184 8.46714354905184e-26 301.070245263297 45.4172623745416 6.62898267140074 8.35112702641976e-11 -393.153068629774 79.0702659371038 -4.97219863839217 8.95939580047727e-07 EIF3J other 1.10665566186107e-21 0.0114088946123278 9.64137615200161e-07 6.62898267140074 -4.97219863839217 1.51024960430339e-36 101.257555958693 77.9762430754309 1.29856930733045 0.194656497776521 -1613.16197051665 138.828783581405 -11.6197947493413 5.81621778069719e-28 SPG11 other 2.17370225547387e-32 9.08667703878321e-24 1 1.29856930733045 -11.6197947493413 0.288064508535863 121.576930065781 78.7881769841764 1.5430859644106 0.123391406345745 59.1659272068718 138.420959643297 0.427434742248132 0.669231843142713 RHOV other 1 1 1 1.5430859644106 0.427434742248132 1.78676994286646e-30 111.979521254043 25.5201409979946 4.38788803176452 1.37511369289667e-05 -369.999901573613 44.835691627744 -8.25235182375685 1.17922862333724e-15 VPS18 essential 2.45466454750995e-26 1.7798097612029e-11 0.122577634584809 4.38788803176452 -8.25235182375685 2.51548322155023e-06 30.4374427759081 6.70323165644932 4.54071175454955 6.9084933214558e-06 49.5641846171263 11.4807651077799 4.31714995924263 1.87834107310678e-05 OIP5 essential 0.0161946809803404 0.222959174894798 0.062991642105034 4.54071175454955 4.31714995924263 0.00359054032092302 -0.402850536750698 12.0060946495101 -0.0335538364897978 0.973245402491056 -63.6676356647833 21.2009380858963 -3.00305747825082 0.00279734069092205 SLC30A4 other 1 1 1 -0.0335538364897978 -3.00305747825082 3.38306451317514e-22 40.6062165633197 32.7536142951242 1.23974765647053 0.215609225725312 -498.000800793124 57.8962193404462 -8.60161175403765 8.63212238105738e-17 BLOC1S6 other 4.18315927054105e-18 1.31165099580167e-12 1 1.23974765647053 -8.60161175403765 3.38443893703192e-14 145.216760254956 39.1029947989565 3.71369919366972 0.000225733324879233 -325.381678527484 68.5426497688613 -4.74714181060599 2.65331328118513e-06 MYEF2 other 3.39086937101228e-10 0.033049670230442 1 3.71369919366972 -4.74714181060599 6.51106977247527e-08 364.584972548905 69.103446452891 5.27593038065689 1.93371674220639e-07 -1244.12458877292 646.270269222657 -1.92508405232592 0.0547577442121699 SGK3 other 0.000477456746415612 1 0.00194377206926587 5.27593038065689 -1.92508405232592 3.03671694202261e-12 25.9550909194333 38.1756015550284 0.679886887493317 0.496867437301585 -416.75465654491 78.042798661564 -5.34007831205779 1.37096900693304e-07 PDGFRL other 2.81655496372597e-08 0.00180433231002457 1 0.679886887493317 -5.34007831205779 1.04939138690363e-34 106.683006857455 8.30685347938386 12.8427697830741 4.88902394242695e-33 -212.224721939338 77.7805738967826 -2.72850547774264 0.0065746480541779 CSPP1 other 1.49370370011862e-30 1 7.262156164081e-29 12.8427697830741 -2.72850547774264 6.86658774840954e-06 75.3692144202043 30.9843017229236 2.43249678802485 0.015321326499632 -111.248168763677 62.970673361031 -1.76666633570608 0.0778532114100505 ZDHHC2 other 0.0423119137056996 1 1 2.43249678802485 -1.76666633570608 8.81714806279661e-90 214.54205577818 8.67815911030745 24.7220698596501 2.74034583071247e-86 -36.6821564349512 54.0495633703628 -0.678676276875629 0.497686529874211 BRF2 essential 1.37450521150936e-85 1 4.27219915008075e-82 24.7220698596501 -0.678676276875629 3.52676090371042e-56 73.6322356241971 9.31926036530941 7.9010814955112 1.53301610554045e-14 -154.348879789621 19.7990936514884 -7.79575482123233 3.26002273550072e-14 TRIM35 other 5.39030136523101e-52 4.86004189408447e-10 1.94294461216197e-10 7.9010814955112 -7.79575482123233 7.16889530953091e-39 167.382805725906 11.6904677284601 14.3178878393734 2.09619700537697e-39 -61.0693824785987 120.79596876015 -0.505558116760143 0.613382355311478 ZFAND1 other 1.04429297973937e-34 1 3.16504785841869e-35 14.3178878393734 -0.505558116760143 0.000209831636749508 17.2327990687189 4.68026170439654 3.6820161258356 0.000256692863562693 -54.5355854568042 37.2834035935829 -1.46273087219405 0.144171837091544 RP1 other 1 1 1 3.6820161258356 -1.46273087219405 0.889802593923489 131.740232879516 530.338131691013 0.248407996723627 0.803917386269024 -2387.45008496266 5817.07966135387 -0.410420730667285 0.681667372893325 CA2 other 1 1 1 0.248407996723627 -0.410420730667285 2.11175899118165e-27 149.052966747801 21.615321652823 6.89570893932702 1.49729108364561e-11 -137.636999393299 44.5147352656596 -3.09194244494312 0.00209081781281436 FZD3 other 2.81539708704338e-23 1 1.76740239513527e-07 6.89570893932702 -3.09194244494312 2.26391936650202e-76 96.2834868074621 11.3823115186964 8.45904512886584 2.52679492900013e-16 -240.783790191451 22.941219093153 -10.4956841750103 1.39500137910276e-23 INTS9 essential 3.51473481649439e-72 2.16713464243614e-19 3.30706920307536e-12 8.45904512886584 -10.4956841750103 5.45156573250726e-12 100.11102665188 13.9496198605751 7.17661324483951 2.46744392654605e-12 301.865103656389 136.299679731641 2.21471616258181 0.027210641954543 RIPK2 other 5.00453734244167e-08 1 2.97401016466595e-08 7.17661324483951 2.21471616258181 0.357287231645664 6.93016172272967 5.05777293957227 1.37020024535062 0.171206705859008 28.7594745592172 48.411634615676 0.594061216637884 0.552725602311146 EYA1 other 1 1 1 1.37020024535062 0.594061216637884 3.19692866876531e-25 401.166641908483 36.0668596136722 11.1228603267807 6.28676392158756e-26 -203.649368694007 361.88372728893 -0.56274806888847 0.573848978395017 NBN ts 4.14226047611921e-21 1 9.05294004708609e-22 11.1228603267807 -0.56274806888847 0.86258953050316 30.1630855269037 56.0696595978599 0.537957350610614 0.590833599945324 -8.25313579326217 526.266239516268 -0.0156824344287186 0.987493675738888 TRPA1 other 1 1 1 0.537957350610614 -0.0156824344287186 2.84118828964137e-05 83.7488137199925 18.2186305950225 4.59687753605772 5.35881534332091e-06 116.067667636108 189.604139673232 0.612157877123049 0.540693868120489 CPQ other 0.165158275276853 1 0.0492475130051192 4.59687753605772 0.612157877123049 4.15473964804966e-18 211.798034778416 22.8349980861193 9.2751500998444 4.73649592457393e-19 16.0306700788774 229.941100261483 0.0697164189466249 0.944446174526343 DECR1 other 4.70108791176819e-14 1 6.44447635497529e-15 9.2751500998444 0.0697164189466249 5.18555836007269e-56 944.904043659031 52.9503682958553 17.8450891668868 1.11980368321335e-55 -558.402121867492 433.05405866427 -1.28945130681802 0.197826851894563 IMPAD1 other 7.92197750668305e-52 1 1.72494559362184e-51 17.8450891668868 -1.28945130681802 0.791164872323577 -180.25816172358 398.306952087514 -0.452560922622245 0.651096407022314 -1090.69959428981 1710.43980599043 -0.637672013051779 0.524031407144022 SFRP1 other 1 1 1 -0.452560922622245 -0.637672013051779 7.90362600563195e-08 1547.80990091654 266.66607977762 5.80429990273716 1.11376880176555e-08 1484.96491406338 3003.77407569554 0.494366379308848 0.621252294036064 LAPTM4B other 0.000575621081990175 1 0.000119028471844684 5.80429990273716 0.494366379308848 1.72788277602545e-47 252.814215035314 15.6276683141265 16.1773471226533 5.21640103610024e-48 -143.644217372626 157.159814751402 -0.914000933380106 0.361138330676338 UBE2W other 2.59648944753344e-43 1 7.9779637446117e-44 16.1773471226533 -0.914000933380106 1.18597373961771e-23 64.1712628039344 6.06409905055387 10.5821594055383 7.15377220695324e-24 184.179792171056 68.0396920865108 2.7069462915393 0.00700958152896057 POP1 essential 1.50144275435602e-19 1 1.01755255871703e-19 10.5821594055383 2.7069462915393 1.80129285712501e-13 130.672223563499 16.7818398930122 7.78652545826692 3.64374017228265e-14 -136.696974275219 184.300897165635 -0.741705419656024 0.458594370609228 NIPAL2 other 1.75445924283976e-09 1 4.58564700681772e-10 7.78652545826692 -0.741705419656024 3.75087510642845e-24 192.27203822856 37.0312374730738 5.19215806299655 3.28672412126069e-07 -1240.73138726991 162.642322409943 -7.62858872700192 1.68989760397675e-13 IKBKB other 4.78574154829206e-20 2.50273835148956e-09 0.00326108767311486 5.19215806299655 -7.62858872700192 0.00178851974062939 -199.302252296671 231.418026922235 -0.86122181122754 0.389621728449739 -3630.32843021619 1016.39501984039 -3.57176920326338 0.000396885855139925 PLAT other 1 1 1 -0.86122181122754 -3.57176920326338 1.45086155214507e-08 92.9618274193472 15.2747627498933 6.08597520900917 2.24062566463808e-09 -13.8215116929086 155.068808468641 -0.0891314754359752 0.929011543730327 JPH1 other 0.000111121486278791 1 2.45751822897504e-05 6.08597520900917 -0.0891314754359752 3.79735190077979e-39 172.75939475944 11.9295957314695 14.4815799837804 2.63207961790387e-40 9.64752191732092 143.032141740477 0.0674500276645913 0.946248784964829 STK3 other 5.53881748247741e-35 1 3.97996759023244e-36 14.4815799837804 0.0674500276645913 0.233809423627683 128.555332690528 91.6679722959642 1.40240183643931 0.161388564784954 -798.928652540523 930.609756198726 -0.858500190030156 0.391009600922102 GDAP1 other 1 1 1 1.40240183643931 -0.858500190030156 1.90389527741265e-66 1080.39897445885 54.2743235250283 19.9062632988991 8.09324845612556e-66 -767.354673895247 463.587818770139 -1.65525202092449 0.0984825979358351 RAB2A other 2.9413278140748e-62 1 1.25356325336929e-61 19.9062632988991 -1.65525202092449 1.59137149359682e-31 1011.27474069026 79.5487601619277 12.7126398781292 1.66849114006872e-32 925.382718529351 917.183550756475 1.00893950591036 0.313464039978592 EIF3E other 2.20834622166431e-27 1 2.47470605894993e-28 12.7126398781292 1.00893950591036 4.24744507425567e-82 238.810651176521 10.2312142528146 23.3413791633603 2.06768635735807e-83 -10.5617163274684 117.964144228584 -0.089533276374239 0.928691932055351 EMC2 other 6.6102987690641e-78 1 3.22228241930681e-79 23.3413791633603 -0.089533276374239 2.79997638566968e-55 767.347406764418 42.8421177632767 17.9110521801088 1.6413264641727e-56 657.9464264485 496.922307481358 1.32404284642259 0.186056340900864 ESRP1 other 4.27192397161622e-51 1 2.53010474452221e-52 17.9110521801088 1.32404284642259 0.0006090123269788 -39.7143741553474 12.4983112026535 -3.17757923541829 0.00156974193116742 -290.02599056899 116.460297426093 -2.49034217650906 0.0130604007359562 WISP1 other 1 1 1 -3.17757923541829 -2.49034217650906 4.37657889673612e-16 2336.5496835862 278.092886557163 8.40204764858634 3.87195731465186e-16 7457.570212084 2513.34653556878 2.96718741587949 0.00313804338165545 NDRG1 other 4.67768752483157e-12 1 5.05135551269481e-12 8.40204764858634 2.96718741587949 1.38867504625739e-09 64.9065011399737 10.0207801924599 6.47719038771179 2.17491001897364e-10 -15.7158587417679 98.5365234186886 -0.159492726113241 0.873342857108386 ZC2HC1A other 1.128715077598e-05 1 2.47830996662046e-06 6.47719038771179 -0.159492726113241 8.56727343627101e-05 7.55492172306198 1.73026009985613 4.36635030981189 1.52564447172888e-05 4.70290491501055 17.0142055001587 0.276410492101243 0.782342836391183 IL7 other 0.469657929776377 1 0.135385690421221 4.36635030981189 0.276410492101243 0.14312026488246 -0.962652609858725 2.27836118598975 -0.422519754891512 0.672821350170223 -43.89372217959 22.4154891726677 -1.95818711969542 0.0507454144868256 STMN2 other 1 1 1 -0.422519754891512 -1.95818711969542 9.13303264176256e-70 302.035734748671 14.4841998565179 20.8527732108553 9.12670134182733e-71 99.7508418382382 128.716304666783 0.774966637649132 0.43870893588261 ARMC1 other 1.41297148000709e-65 1 1.41710291734553e-66 20.8527732108553 0.774966637649132 0.00233033623161733 700.009695112444 258.701013517281 2.7058637521174 0.00703903467095664 -6722.5582669203 3073.46275146842 -2.18729127714609 0.0291710881673643 TRPS1 other 1 1 1 2.7058637521174 -2.18729127714609 2.79131088832772e-23 90.6601331171403 8.64358658761639 10.4887169461608 1.61238461079162e-23 -212.128209561844 124.861495662029 -1.69890812565649 0.0899222404502158 SPAG1 other 3.5125856218716e-19 1 2.28652261656359e-19 10.4887169461608 -1.69890812565649 1.07996125359523e-39 158.083497902298 10.8583290910083 14.5587315117577 9.61065132743491e-41 62.7996233686601 85.4926018071616 0.734562079538905 0.462925092492884 CHRAC1 other 1.57965932563374e-35 1 1.454475971894e-36 14.5587315117577 0.734562079538905 0.00102677184573282 101.322045307081 27.3108338335352 3.70995795751452 0.000229094010716392 -126.844049472297 376.201329373442 -0.337170657221105 0.736121234386689 NCALD other 1 1 1 3.70995795751452 -0.337170657221105 2.17502905873507e-15 45.2168190027101 5.36475108877441 8.42850269368974 3.49737462727814e-16 -9.93147277114319 55.4072313159355 -0.179245064863705 0.857815504143013 SNX16 other 2.27312286928402e-11 1 4.56757126322525e-12 8.42850269368974 -0.179245064863705 1.1399593141484e-51 933.500632187182 54.6554449143934 17.0797371359673 1.88972229830932e-52 -992.127056811218 682.160698731117 -1.45438905914203 0.146429295035052 UBR5 other 1.7292042836317e-47 1 2.90299139466278e-48 17.0797371359673 -1.45438905914203 3.15439538639664e-11 235.281432100567 39.1315251915231 6.01258016264428 3.48697367739632e-09 -831.523071802341 268.696811957838 -3.09465179636303 0.00207883869666227 GSDMD other 2.79132447742238e-07 1 3.79731433468459e-05 6.01258016264428 -3.09465179636303 1.94499091637103e-07 267.456815396007 54.0315379033675 4.95001300674319 1.01305118912655e-06 -767.311884224289 367.089748625952 -2.09025691154929 0.0370942441085693 TSTA3 other 0.0013776370660656 1 0.00974352633701918 4.95001300674319 -2.09025691154929 1.43309674555378e-29 183.648706960591 15.3234491959022 11.9848152079038 2.70211870389347e-29 -154.036274432149 103.957527299551 -1.48172314630279 0.139038901705712 PYCR3 other 1.95230769646792e-25 1 3.95833368933355e-25 11.9848152079038 -1.48172314630279 2.62054285637912e-08 1122.01473686151 200.078411041857 5.60787508766642 3.37376844472351e-08 -2050.59250455361 1364.98712355267 -1.50227974254915 0.133648670066243 EEF1D other 0.000197746163942369 1 0.000353098605424763 5.60787508766642 -1.50227974254915 8.65164356426551e-45 808.57528827101 51.5041717040056 15.6992193354335 6.45070420077332e-46 631.178871464772 580.811460518653 1.08671903770828 0.277653124643742 SQLE other 1.2909982526597e-40 1 9.83990418785963e-42 15.6992193354335 1.08671903770828 7.31473826838952e-31 134.912422828605 33.9368419420796 3.97539709377973 7.97645564677379e-05 -475.758634915816 69.4419733839411 -6.85116812976168 1.99216960862223e-11 SH2D4A other 1.00855611244555e-26 2.87988038622429e-07 0.665076871827999 3.97539709377973 -6.85116812976168 2.01891862358823e-47 222.812399361821 32.4223939982183 6.87217604517621 1.73998570997411e-11 -470.403956034829 66.0948250421281 -7.11710721278102 3.5045752733493e-12 INTS10 essential 3.0330214482166e-43 5.11738081414465e-08 2.04952916777851e-07 6.87217604517621 -7.11710721278102 4.58641386916289e-10 117.453326939395 26.3331007680085 4.46029231324276 9.97024128732769e-06 -62.7017940388351 54.7142346873302 -1.14598686058849 0.252310053834186 ERI1 other 3.82873829797718e-06 1 0.0898518144813971 4.46029231324276 -1.14598686058849 3.87860123519837e-07 298.305016374105 94.642152074375 3.15192554095431 0.00171249411225907 -294.184810864211 191.264874569285 -1.53810160661592 0.124612769621263 SLC39A14 other 0.00268321633451023 1 1 3.15192554095431 -1.53810160661592 4.55913470757255e-31 67.8142847064705 13.2159646992265 5.13123984891088 4.01633888329879e-07 -160.315412583365 27.5272406543872 -5.82388240783641 9.8610124607744e-09 MTMR9 other 6.3025478197483e-27 0.000134869067426011 0.00396492974559256 5.13123984891088 -5.82388240783641 3.76498233068837e-61 266.220972760554 29.3274027497242 9.07755027038859 2.13629124689681e-18 -468.982386168051 60.2443998079077 -7.78466359800122 3.64958810551823e-14 LEPROTL1 other 5.79393130869634e-57 5.43898115365382e-10 2.88506132893414e-14 9.07755027038859 -7.78466359800122 8.22959636116007e-90 149.402877285226 12.6483642678443 11.812031510276 9.12009723007139e-29 -263.431224948139 25.9630409368777 -10.1463933130407 3.06985636836852e-22 DCTN6 essential 1.28299407270486e-85 4.7582773709712e-18 1.33271980823033e-24 11.812031510276 -10.1463933130407 1.61862002416782e-49 135.549435338271 20.7849568022766 6.52151633644118 1.58998598064995e-10 -317.266707167902 42.0932016436158 -7.53724342125497 2.01420143663922e-13 R3HCC1 other 2.44395437449099e-45 2.98081670608238e-09 1.8195799562558e-06 6.52151633644118 -7.53724342125497 2.06517612036989e-14 320.35204617397 90.404160396444 3.54355424318028 0.000429241679203289 -707.087140478104 190.183673028968 -3.71791715459404 0.000222010620434904 GSR other 2.08438225828933e-10 1 1 3.54355424318028 -3.71791715459404 5.45172605248881e-26 67.0009368014598 11.788076081699 5.6837889692177 2.14840794323563e-08 -92.7739790317341 23.8729321507607 -3.8861576971716 0.000114381075246501 TNFRSF10A other 7.14612250960233e-22 1 0.000226871878805683 5.6837889692177 -3.8861576971716 9.5752353965294e-33 46.0978684635943 8.49336113091218 5.42751776982824 8.67644521021706e-08 -109.656412973227 17.8847884285258 -6.13126699325824 1.69447808268697e-09 UBXN8 other 1.34369278319497e-28 2.36193299945737e-05 0.000889682691855657 5.42751776982824 -6.13126699325824 1.69578985309273e-56 322.246754030275 41.1700843147551 7.82720656014746 2.6803607069276e-14 -716.512605443288 86.6799120928721 -8.26618980272603 1.09415858275864e-15 PPP2CB other 2.59337142233471e-52 1.65174179653244e-11 3.38020288750639e-10 7.82720656014746 -8.26618980272603 2.0150310915633e-47 74.260745753294 7.86117496188087 9.44651990489807 1.29827645293559e-19 -72.1916829747099 16.1768682230113 -4.46264888725611 9.99013569912056e-06 ERICH1 other 3.0273827119647e-43 0.120620898431182 1.77760011935941e-15 9.44651990489807 -4.46264888725611 0.574111570600124 -2.46632024294261 3.07903691449413 -0.801003791585857 0.423480438988888 -6.46633496826484 6.21196013519171 -1.04094920565122 0.298363230591396 NEFM other 1 1 1 -0.801003791585857 -1.04094920565122 6.45630684679637e-12 263.504138065239 72.0628223839252 3.65658920020343 0.000280703508955807 -403.493862097647 148.025119063436 -2.72584723897253 0.00662267874885234 TUSC3 other 5.906875134134e-08 1 1 3.65658920020343 -2.72584723897253 1.81369586109056e-25 89.0880748565502 23.6004674589736 3.77484365559361 0.000178822877130842 -289.668352007408 49.1596600426965 -5.89239941358063 6.89811020968029e-09 ARHGEF10 other 2.35961831527882e-21 9.47386456197492e-05 1 3.77484365559361 -5.89239941358063 2.13844525234546e-20 820.075034739733 81.9272662452028 10.0097937148947 1.96302119159034e-21 676.705879223992 656.848416296529 1.03023142392491 0.303453554748059 MCM4 essential 2.55116518604813e-16 1 2.73389961352787e-17 10.0097937148947 1.03023142392491 8.86811362073271e-19 116.803008078541 26.0652254086717 4.48118158378487 9.05458091320112e-06 -182.146676857357 52.2921035841638 -3.4832539594471 0.000535232885002815 KCTD9 other 1.01974438524805e-14 1 0.0818805751980777 4.48118158378487 -3.4832539594471 0.536914302144299 138.947934840098 131.233346973734 1.0587852710021 0.290170956855626 252.602505829169 268.308101047495 0.941464327178306 0.346887932063079 FGL1 other 1 1 1 1.0587852710021 0.941464327178306 5.49272836059943e-20 641.485834254726 598.605534396692 1.07163365086701 0.284361550270523 -8518.76896600718 1234.94492120078 -6.89809627924466 1.47434775030945e-11 ASAH1 other 6.50229183327761e-16 2.13574015109828e-07 1 1.07163365086701 -6.89809627924466 2.75542386260758e-45 526.729027308477 104.235002452671 5.05328358914408 5.9366822390408e-07 -1739.24058320136 211.092585159916 -8.23923105533896 1.29560975267546e-15 BNIP3L other 4.11853204743955e-41 1.95481599483673e-11 0.00579004618773649 5.05328358914408 -8.23923105533896 3.4996085893215e-07 280.714034474369 69.6380516079805 4.03104377552975 6.35618560279144e-05 -543.28147182259 216.744412159392 -2.5065535319225 0.0124858875551795 MAN2B1 other 0.00243117808700165 1 0.535000142186956 4.03104377552975 -2.5065535319225 8.80349795521403e-05 344.739691787003 80.1080094570728 4.30343600001368 1.99198566141245e-05 506.008345173122 249.828837592191 2.02542008380596 0.0433084158491984 KCNN4 other 0.481551338150207 1 0.17507561978154 4.30343600001368 2.02542008380596 6.70565714090329e-12 968.942365406319 142.15177834188 6.8162521546229 2.4801833112794e-11 -482.128424231564 454.363715413656 -1.06110679148891 0.289110505276265 NUCB1 other 6.13232345535606e-08 1 2.90925502413073e-07 6.8162521546229 -1.06110679148891 0.000348788072274472 6.45328676154413 2.72758642195927 2.36593301300738 0.0183329905035103 32.1374024222803 8.70577879416833 3.69150229773906 0.000245317630447453 DHDH other 1 1 1 2.36593301300738 3.69150229773906 4.09544048699324e-09 236.898968070704 42.3393653904846 5.59524135248245 3.49221026004719e-08 -166.820989709187 128.873621921378 -1.29445411110552 0.196056797309437 GYS1 other 3.24522704189344e-05 1 0.000365145504790535 5.59524135248245 -1.29445411110552 0.14529319962418 8.11970876548873 4.35002508916766 1.86658895041968 0.0624957911908631 -6.41131389493108 25.3526138160661 -0.252885715904693 0.800451881657322 MAP4K1 other 1 1 1 1.86658895041968 -0.252885715904693 2.59662271327574e-20 520.447379652758 60.8789864289074 8.54888378045717 1.26135882181115e-16 -967.744778286308 324.105712353636 -2.98589238448963 0.00295480013853007 ECH1 other 3.09413562513938e-16 1 1.65944366597474e-12 8.54888378045717 -2.98589238448963 2.45323847174896e-09 298.149980545548 49.7119321182947 5.9975536624903 3.65459722530741e-09 -235.084762437948 264.654885318936 -0.888269121330018 0.374788582209135 HNRNPL essential 1.96847854973136e-05 1 3.976567240857e-05 5.9975536624903 -0.888269121330018 1.94040030861336e-31 132.713898428384 10.5753360371518 12.5493788530363 6.52621676041361e-32 46.6921133981096 56.2976962635665 0.829378757871603 0.407253223795395 NFKBIB other 2.69191734813931e-27 1 9.65553769703194e-28 12.5493788530363 0.829378757871603 4.51810235847111e-07 56.6178866124985 10.3339787936382 5.47880808961534 6.55096484403846e-08 47.7428774738266 24.6196873056583 1.93921542873755 0.0529908637704486 TUBB4A other 0.00310574356121304 1 0.000676452629795411 5.47880808961534 1.93921542873755 3.94179217706129e-46 133.989420554048 8.65529981340242 15.4806215200737 4.55198994575354e-45 -17.3428305235985 46.0764025136614 -0.376392894789396 0.706771311608986 SARS2 other 5.90283378514929e-42 1 6.9335910853718e-41 15.4806215200737 -0.376392894789396 6.03754553885275e-05 148.719327811156 128.100510167706 1.16095812277763 0.246167178035176 -1629.00250403446 423.004514821733 -3.85102864616225 0.000131592386304937 SNRNP70 essential 0.337800672898811 1 1 1.16095812277763 -3.85102864616225 1.2386091410336e-17 421.177003987674 66.8464824334956 6.30066068781848 6.10030317340719e-10 -979.57779256907 218.965660081083 -4.47365944142262 9.35751789648886e-06 CLPTM1 other 1.38464115876147e-13 0.113169821440136 6.84881037278425e-06 6.30066068781848 -4.47365944142262 0.414040174088771 32.0081884588526 24.5080560701433 1.30602722497629 0.192092243481335 12.4589963195548 76.8979489223185 0.162019878217308 0.871350029289204 RELB other 1 1 1 1.30602722497629 0.162019878217308 8.3016171317762e-05 47.7373113371653 23.4206871223534 2.0382540908291 0.0420058632597185 -225.222207376757 73.4812730370975 -3.06502865380478 0.00228406749483259 CLASRP essential 0.456090845219784 1 1 2.0382540908291 -3.06502865380478 3.13313700529401e-06 15.4695915806278 3.25701330618337 4.74962492516045 2.60928894742025e-06 -6.00331785942491 10.7719808224556 -0.557308628595977 0.577545389962808 LIN7B other 0.0199831478197652 1 0.0244847554802559 4.74962492516045 -0.557308628595977 3.1798140205724e-08 102.649835521776 54.8427341861612 1.87171258043656 0.0617847514413668 -757.379430292785 161.005631852713 -4.70405551394395 3.24081931611248e-06 PPP1R37 other 0.000238581445963547 0.0401861595197948 1 1.87171258043656 -4.70405551394395 0.00014546168282634 570.769133029425 165.521160960607 3.44831518651119 0.000607779869403312 -938.68208944448 601.018378068904 -1.56181927823988 0.118912092772749 FCGRT other 0.773274305904824 1 1 3.44831518651119 -1.56181927823988 4.48135379685954e-17 255.356748773048 31.0057168447862 8.23579567766025 1.32910597784091e-15 -162.701719721302 110.911696502575 -1.46694825570111 0.142966920965104 PIH1D1 other 4.93576307186109e-13 1 1.71654037038154e-11 8.23579567766025 -1.46694825570111 0.848883897731779 576.47229905214 1313.32901516582 0.43893974198031 0.660878524927315 -774.444184159937 3912.85987483593 -0.197922800440792 0.843178995437931 CKM other 1 1 1 0.43893974198031 -0.197922800440792 1.0449749015195e-90 1056.15253956531 43.1229950424318 24.4916323304094 6.10534690085383e-90 312.970609398735 154.529974355453 2.02530680991918 0.0433218542395926 ARHGEF18 other 1.62942936393935e-86 1 9.52434116533197e-86 24.4916323304094 2.02530680991918 1.45781684367765e-06 121.474354194739 35.4413330272784 3.4274770111283 0.000655055552568875 -273.026265420078 105.591948637201 -2.58567314027093 0.00997636382511146 PPP1R13L other 0.00958514574718055 1 1 3.4274770111283 -2.58567314027093 3.09581930658827e-73 232.429616764576 10.9839017829401 21.1609336425039 4.98928032777603e-73 84.0623002299186 39.3162158441238 2.13810760840257 0.0329512889853799 PEX11G other 4.80006783486512e-69 1 7.75384055739673e-69 21.1609336425039 2.13810760840257 8.06393933515417e-16 119.074929655494 17.1977654487908 6.92386054514228 1.23648342130752e-11 -127.099692379467 51.238071788825 -2.48057133967299 0.0134168608963841 ERCC2 ts 8.55261405886451e-12 1 1.46362542580172e-07 6.92386054514228 -2.48057133967299 2.26034270875854e-08 77.4577337794059 29.154372819539 2.65681358535329 0.00812934167221481 -186.325371372325 53.2062259037687 -3.50194677798274 0.000501387856061798 DOT1L other 0.000171288770469723 1 1 2.65681358535329 -3.50194677798274 0.261056544636256 2.03662519725491 2.11071848698708 0.964896650032223 0.335023741435664 -7.9452626871798 7.56106408531703 -1.05081276888115 0.293809448410613 SLC17A7 other 1 1 1 0.964896650032223 -1.05081276888115 1.39161075316398e-20 247.17137131184 25.5373225419995 9.67882873802976 1.5499486963847e-20 45.7608634242542 79.4675812685317 0.575843163888706 0.564961536521107 RNASEH2A other 1.6658972326126e-16 1 2.14171910866437e-16 9.67882873802976 0.575843163888706 3.16211526787015e-10 81.3107769240858 12.1467249703047 6.69404939379691 5.39005110173747e-11 52.4997630884523 36.1892809784393 1.45069925870399 0.147436809235916 KLC3 other 2.65997136333237e-06 1 6.25192027290529e-07 6.69404939379691 1.45069925870399 0.68902440827912 15.5589003081176 19.1084806859775 0.814240575365852 0.415862116468635 -5.08423481074932 67.2553794217245 -0.0755959575942417 0.93976824243629 CD37 other 1 1 1 0.814240575365852 -0.0755959575942417 1.52257146436043e-08 95.2642358877197 57.6411433121674 1.65271246220424 0.098998858610212 -462.142384198241 105.373010415936 -4.38577565900453 1.4021156643749e-05 SF3A2 essential 0.000116446265594286 0.167791181555745 1 1.65271246220424 -4.38577565900453 7.02558534743293e-05 4.26896826502363 0.967676521922067 4.41156540260406 1.23679550566108e-05 3.94082759262491 3.40589357724931 1.15706128310904 0.2477532729237 DKKL1 other 0.389709219222105 1 0.110631357981384 4.41156540260406 1.15706128310904 0.00107577328613165 -5.67388474132832 3.33321219783557 -1.70222728244325 0.0892904405837673 -41.0438213560774 11.2115547867652 -3.66085009052698 0.000276188105831672 LYL1 other 1 1 1 -1.70222728244325 -3.66085009052698 3.14278117194819e-10 1525.02410142351 355.75902268304 4.28667722865378 2.16550677052063e-05 -1675.18476315525 651.205227938851 -2.57243752243425 0.0103775683490798 OAZ1 other 2.6446503561944e-06 1 0.18995825391007 4.28667722865378 -2.57243752243425 2.38572266388905e-27 202.532683911447 19.4905911603364 10.3913053352432 3.56869065315457e-23 -143.588090405142 65.5583316185057 -2.1902340535556 0.0289357596465196 TRMT1 other 3.178259732833e-23 1 5.04719919075651e-19 10.3913053352432 -2.1902340535556 2.32137516475853e-23 199.068421726159 20.4344238594111 9.7418171951287 9.27787350649096e-21 -102.857934088035 69.0999479266162 -1.48853851810814 0.137195932409959 STX10 other 2.9244684325628e-19 1 1.28483740757494e-16 9.7418171951287 -1.48853851810814 0.494776317266899 -0.742544193907445 1.85374673649953 -0.400563992527699 0.688897560406685 6.5666076052227 6.72396072666256 0.976598149835124 0.329199831429311 FCER2 other 1 1 1 -0.400563992527699 0.976598149835124 4.5824387568616e-06 67.3073783107367 31.9473577403175 2.10682144225639 0.0355878014585387 -343.368876603126 95.6819225982119 -3.58864942592137 0.000362243349641081 DMPK other 0.0287227261280085 1 1 2.10682144225639 -3.58864942592137 0.0125791711457433 28.2767304378022 15.2438559369056 1.85495917534511 0.0641458725280154 143.373335476374 52.2365415572337 2.74469425429487 0.00625798169920664 IL4I1 other 1 1 1 1.85495917534511 2.74469425429487 4.66387585158235e-10 16.6921531470509 10.2557235243294 1.62759390963032 0.104188966332244 -111.030798518998 21.5653656834567 -5.14857017259727 3.67162932593407e-07 TLE6 other 3.89247078573063e-06 0.00474851820723054 1 1.62759390963032 -5.14857017259727 1.34166531024832e-18 140.729798790949 17.5238515019938 8.03075732380738 6.16331380872132e-15 -159.44709380776 61.8224302909912 -2.57911397299104 0.0101702996958236 CCDC130 essential 1.53634094676535e-14 1 7.87178439649887e-11 8.03075732380738 -2.57911397299104 4.05717841520828e-08 417.986419861038 94.9909972104497 4.40027404844483 1.30321312051833e-05 -833.5873238584 312.974153909125 -2.66343822148471 0.00796558251535626 PTOV1 other 0.000302056933012256 1 0.116350867399876 4.40027404844483 -2.66343822148471 2.72790723978861e-20 839.777696137057 269.373093586377 3.11752627167187 0.00191997999771895 -4013.81001580976 563.580179729372 -7.12198576205637 3.37935975684434e-12 AES other 3.24948310403619e-16 4.93623079682253e-08 1 3.11752627167187 -7.12198576205637 0.170002459992582 -5.91750579946809 5.10523564923062 -1.15910531972405 0.246919000373864 -27.0592674167996 15.0648760572638 -1.79618254501022 0.073017175791618 NOVA2 other 1 1 1 -1.15910531972405 -1.79618254501022 3.39056021009266e-24 340.324848562337 54.3306110552233 6.26396136455045 7.63148829514793e-10 -592.197765063149 113.305779586711 -5.22654508201808 2.46558424996044e-07 SGTA other 4.32838916420428e-20 0.00320772510919853 8.53505650929345e-06 6.26396136455045 -5.22654508201808 0.569352876930709 -0.737471709439664 4.69010367656385 -0.157239958921327 0.875113759309157 -25.1114118410389 23.6480203377863 -1.06188219911644 0.288757762561428 LILRB1 other 1 1 1 -0.157239958921327 -1.06188219911644 0.000151333100880408 -1.98732091867785 0.795300144465272 -2.49883133117502 0.0127525309195628 -14.9448539277503 4.00999109783817 -3.72690451502679 0.000214010647665002 LILRA1 other 0.803578765674966 1 1 -2.49883133117502 -3.72690451502679 8.44426516718365e-05 3.57160788598096 47.7110993291331 0.0748590566178819 0.940354271576537 -541.412728224004 132.573711420036 -4.08386189407216 5.0927172640391e-05 SNAPC2 essential 0.463336829723367 0.587190300543708 1 0.0748590566178819 -4.08386189407216 6.84265621295831e-20 352.487547325712 40.4376328094047 8.7168195276686 3.58652368284283e-17 -296.68849498461 147.488362303002 -2.01160613862598 0.0447614592977908 C19orf53 essential 8.08733537809542e-16 1 4.76397940792013e-13 8.7168195276686 -2.01160613862598 1.00585821263865e-28 231.862109789821 21.3472223555628 10.8614650621935 5.14690137199761e-25 -73.9634565520038 59.3170255135503 -1.24691782690802 0.212962253299271 TIMM44 essential 1.35981971766619e-24 1 7.37396559566098e-21 10.8614650621935 -1.24691782690802 1.34031554922325e-06 15.5646054839228 8.30415565079936 1.87431523907244 0.0614207142026125 -97.8910625584564 24.6590066459549 -3.96978937407906 8.15551485025974e-05 CCDC61 other 0.00884876325597187 0.92532471491047 1 1.87431523907244 -3.96978937407906 0.00030225597503313 127.37767357252 32.6399739375223 3.90250537014334 0.000107422307428959 241.271936643167 113.059446527272 2.13402722243972 0.033297177469262 IL27RA other 1 1 0.885052390907193 3.90250537014334 2.13402722243972 2.63954598795556e-22 282.630491310517 27.14154935234 10.4132040378951 3.04471933888507e-23 197.075071547567 94.8594218065689 2.07754873258061 0.0382282355896461 ASF1B other 3.27066143367574e-18 1 4.30980022419182e-19 10.4132040378951 2.07754873258061 0.468226675053864 269.206691300777 234.909865997478 1.14599993558239 0.252301824795766 -260.837335164886 896.455968966076 -0.290965026944627 0.771189580500773 TNNT1 other 1 1 1 1.14599993558239 -0.290965026944627 7.42887296334454e-26 152.325382241828 16.5943738350398 9.17933895885761 9.08980246576978e-19 -225.725190942001 56.6783066044903 -3.98256766062446 7.74794809101787e-05 VRK3 other 9.717708723351e-22 0.88039934158236 1.23321350053099e-14 9.17933895885761 -3.98256766062446 6.11888265202252e-35 332.543494508563 27.7891009698157 11.9666877625789 1.80479593969941e-29 -294.189247257301 99.2565568048706 -2.96392759055354 0.00316994392241086 FAM32A essential 8.72552666178411e-31 1 2.64691372516315e-25 11.9666877625789 -2.96392759055354 1.53121563439994e-32 553.963555199686 43.8306720503893 12.6387191727936 2.88887893252464e-32 -187.00650377107 167.613403756923 -1.11570136742925 0.265045310749133 PPP6R1 other 2.14507998223087e-28 1 4.28045191432176e-28 12.6387191727936 -1.11570136742925 7.39943101472982e-39 207.093653643512 16.0680664076016 12.8885236337795 2.29795791325149e-33 -167.459828554081 59.6372726309719 -2.80797261790125 0.00516412136839474 C19orf44 other 1.07780112160555e-34 1 3.41706341700496e-29 12.8885236337795 -2.80797261790125 6.18663177254659e-31 78.292032312579 6.88927974808484 11.3643276475082 5.20823543466183e-27 -53.7641375365591 25.1611170532395 -2.13679453987663 0.0330585067993899 MED26 other 8.54064516200057e-27 1 7.54725396836846e-23 11.3643276475082 -2.13679453987663 1.07635407607812e-07 173.700422144225 30.3112261804195 5.73056401975689 1.67143189346695e-08 101.483945728051 109.581273251537 0.926106648670711 0.354807344477744 OLFM2 other 0.000777342913743618 1 0.000177322209577908 5.73056401975689 0.926106648670711 0.00723314791565717 -7.11034109168113 7.7427424782558 -0.918323334612941 0.358858088002874 -89.171210513931 28.2825160676986 -3.15287403357204 0.00170619574174851 RASAL3 other 1 1 1 -0.918323334612941 -3.15287403357204 6.04362393304511e-29 146.451736769461 13.5029024709873 10.8459449428841 6.25367967555378e-25 -108.581810587264 47.7923137807026 -2.27195132433841 0.0234819092330533 AKAP8 other 8.19334096602926e-25 1 8.95526929539302e-21 10.8459449428841 -2.27195132433841 0.276258153202388 10.4978139356274 6.76454973215413 1.55188657801241 0.12127630409795 19.2356307524344 23.3807079919367 0.822713784333144 0.411034593374391 EPHX3 other 1 1 1 1.55188657801241 0.822713784333144 6.91905221282899e-13 321.27874037925 45.3962254324989 7.07721263868004 4.58166072349358e-12 -145.40083363802 157.11561937957 -0.925438439616568 0.355150509108594 ILVBL other 6.57379150740882e-09 1 5.48608055031121e-08 7.07721263868004 -0.925438439616568 9.15847336612358e-35 76.3275320253933 5.72602305208822 13.3299379571232 2.80446349226109e-35 5.22800231001617 28.7609688183099 0.18177420736564 0.855827637004208 ZNF419 other 1.30398343786867e-30 1 4.19463604537491e-31 13.3299379571232 0.18177420736564 2.95985738861185e-09 84.7505624570547 13.8887312010957 6.1021097773401 1.9941654700435e-09 -11.5138753949123 52.3273957550282 -0.2200353223924 0.825926494861764 SYDE1 other 2.36255816758998e-05 1 2.1913884350308e-05 6.1021097773401 -0.2200353223924 0.000127896163325079 1193.1177414845 280.498420396998 4.2535631387722 2.47771814236512e-05 1584.34241753752 1078.38853136594 1.46917587813246 0.142364190166954 CASP14 other 0.686802397055672 1 0.216280016647052 4.2535631387722 1.46917587813246 0.865104643468786 2.19738946534777 10.8062482171605 0.20334434497426 0.838941656214751 -18.1210860525981 42.4912846429928 -0.426465949543525 0.669936441365637 SLC1A6 other 1 1 1 0.20334434497426 -0.426465949543525 1.48013847452055e-15 44.1578903682004 5.42030627929955 8.14675187947253 2.55174802972434e-15 93.5092050580756 24.6125208976252 3.79925345506148 0.000161412311524004 AURKC other 1.55577355056855e-11 1 3.28001691740767e-11 8.14675187947253 3.79925345506148 7.81983141903808e-26 134.756823892895 12.3600269916304 10.902631845719 4.80285561557264e-25 -33.8077722047482 48.6666344513079 -0.694680710632942 0.48756869448765 POP4 essential 1.0226775529818e-21 1 6.88153152599248e-21 10.902631845719 -0.694680710632942 7.0779116295965e-11 97.24725938593 14.5618085558637 6.67824048179583 6.2581301363855e-11 208.530395158211 58.3107028360901 3.57619416360637 0.000381364964296777 CCNE1 og 6.15282857960823e-07 1 7.24691469793441e-07 6.67824048179583 3.57619416360637 2.52227706772607e-30 398.277384422646 33.7200071307133 11.8113078351007 1.14601539128351e-28 -161.505189337487 135.026999420213 -1.19609552186576 0.232207549574126 URI1 essential 3.46056413692017e-26 1 1.67432848666521e-24 11.8113078351007 -1.19609552186576 7.90616692747933e-29 330.869597306244 27.4303463730459 12.0621735069073 8.27042099588496e-30 210.337011651974 121.407653704523 1.73248559900419 0.083762365740736 PDCD5 other 1.07025781697288e-24 1 1.21459402745567e-25 12.0621735069073 1.73248559900419 1.36498344118169e-30 320.177981690253 25.7748364741362 12.4221149574134 2.58361162694083e-31 135.732049549627 114.080310120238 1.18979383389271 0.234654178181217 ANKRD27 other 1.87794421837776e-26 1 3.8162527341543e-27 12.4221149574134 1.18979383389271 6.60490139161068e-42 3978.19921966871 270.692932806544 14.6963541989174 2.20081313772608e-41 -39.6040843119618 1510.69915099643 -0.0262157321567565 0.979094934783772 RPS16 essential 9.75411837513065e-38 1 3.33467206628256e-37 14.6963541989174 -0.0262157321567565 4.40894781134138e-73 400.428529542119 19.1048053439566 20.9595712875863 7.50368082110311e-72 25.0482533413899 100.983948463787 0.24804192866723 0.804196083894346 TIMM50 other 6.83519179192255e-69 1 1.16562177875016e-67 20.9595712875863 0.24804192866723 2.95534154626878e-87 2449.82397458236 101.469466852044 24.1434596099192 3.58001589121763e-88 1888.29006250691 597.103794381492 3.16241511153499 0.00165159899417806 FBL essential 4.60530873155065e-83 1 5.58231877917565e-84 24.1434596099192 3.16241511153499 4.73919578318621e-21 101.420300610933 13.3526548400645 7.59551578511731 1.33906626170796e-13 -386.03620806751 78.5745812747246 -4.91299096736883 1.18733875777233e-06 DYRK1B other 5.73205729976372e-17 0.0150257719796089 1.66245076391043e-09 7.59551578511731 -4.91299096736883 0.0536631546686523 35.6721172513279 18.1365544929017 1.96686295984661 0.0497106150566234 -52.6689531899475 68.7245788860769 -0.766377241499807 0.443786755380353 CNTD2 other 1 1 1 1.96686295984661 -0.766377241499807 1.02179862566162e-26 2597.06964599577 224.446046990168 11.5710197654296 7.95789935985691e-28 2527.56797045868 986.593169077183 2.56191513349202 0.010678938966397 GPI other 1.35132868243749e-22 1 1.15827225182717e-23 11.5710197654296 2.56191513349202 9.7528181009673e-23 475.909105803549 63.8840504382115 7.44957626417015 3.70894634811571e-13 -1187.99798867281 242.09140040676 -4.90722919804977 1.2230536232732e-06 AKT2 og 1.21763933990577e-18 0.0154691822271595 4.5549570101209e-09 7.44957626417015 -4.90722919804977 1.02389010798997e-06 494.377994990165 121.27113341261 4.07663374686296 5.25265993114834e-05 -920.353003477516 456.654543692864 -2.01542504326099 0.0443523218055334 PLD3 other 0.00682832313018513 1 0.445320508962757 4.07663374686296 -2.01542504326099 1.44233283584202e-06 -3.0370497539182 7.59080126534181 -0.400096069934647 0.689242816014102 -146.227745301105 28.6209143419096 -5.10912207605414 4.48646757384802e-07 PRX other 0.00949055005984052 0.00578350534944748 1 -0.400096069934647 -5.10912207605414 6.67851996303966e-26 92.1808895843771 17.884823270563 5.15414036749804 3.57123772315175e-07 -323.250895096781 43.1567788027665 -7.49015343740297 2.79747917379729e-13 PIAS4 other 8.74485403960414e-22 4.13383497512025e-09 0.00353552534592024 5.15414036749804 -7.49015343740297 1.34879494906694e-22 158.344708054353 15.4300242796218 10.2621165841895 1.03307975287006e-22 43.3277133444015 60.8870664146994 0.71160783226602 0.477011570028562 NUMBL other 1.67897995259852e-18 1 1.45478290799162e-18 10.2621165841895 0.71160783226602 0.144350674651571 -4.73835426108257 2.63455747805184 -1.79853895789224 0.0726438314493689 -9.01634701500881 6.41729913062816 -1.40500650374486 0.160588019900815 EBI3 other 1 1 1 -1.79853895789224 -1.40500650374486 3.91992009513651e-16 25.1366603174715 12.1528364040311 2.06837807091138 0.0390747255729515 -226.366301184558 31.4628375836363 -7.19471982089406 2.07669664732734e-12 CCDC94 essential 4.19745043787218e-12 3.04173757934035e-08 1 2.06837807091138 -7.19471982089406 1.50294021064585e-25 445.475056155059 42.6970952284292 10.4333808604958 2.41081280664401e-23 -362.76407221146 194.666718161713 -1.86351357662539 0.0629316138717789 TBCB essential 1.95667786023983e-21 1 3.41539850317257e-19 10.4333808604958 -1.86351357662539 0.650728200844515 3.18412095771743 3.75416354360009 0.848157231494497 0.396722074224763 6.30167329194595 9.71926502651829 0.648369323683664 0.517018682217866 FSD1 other 1 1 1 0.848157231494497 0.648369323683664 5.82901788665694e-16 159.485622832542 20.0921666069953 7.93770159048032 1.19491533691291e-14 -152.284773413483 92.4732296460577 -1.6467984734215 0.100180184626418 POLR2I essential 6.20790404928965e-12 1 1.51849841014893e-10 7.93770159048032 -1.6467984734215 0.495787099525552 5.90610592893918 16.5138596908748 0.357645398440848 0.720748183058668 -78.8825973026368 76.1637934906353 -1.03569680142489 0.300806329433933 CLIP3 other 1 1 1 0.357645398440848 -1.03569680142489 0.227113086695139 1.95698864661538 4.51993066137329 0.432968731874481 0.665209408280119 -15.0103011571353 10.8334048067843 -1.38555711937721 0.166451012216215 ZFR2 other 1 1 1 0.432968731874481 -1.38555711937721 8.86035415994644e-12 1124.84145230744 162.598702464968 6.91789931441664 1.28987455796493e-11 98.3540354963977 471.648264180779 0.208532592963598 0.834891047359177 SLC1A5 other 8.05317589597532e-08 1 1.52579261461672e-07 6.91789931441664 0.208532592963598 7.53991534055553e-15 127.214650021605 29.2582468502868 4.34799291538407 1.63936554130657e-05 -438.2025550415 85.4001345117611 -5.13116937750434 4.00827735095921e-07 PRKD2 other 7.74349305475053e-11 0.00517428523235325 0.145100244061045 4.34799291538407 -5.13116937750434 4.85067950267339e-14 88.3175862034862 55.5138298693347 1.59091142533965 0.112210426653327 -894.398045616108 133.611808799952 -6.6940044719792 5.4173075409607e-11 TJP3 other 4.82691117311029e-10 7.77817016731137e-07 1 1.59091142533965 -6.6940044719792 0.266908820818818 51.16886695327 40.0016709263423 1.27916823893408 0.201383167719435 228.970143204839 184.598733376898 1.24036681626275 0.215374452251176 APLP1 other 1 1 1 1.27916823893408 1.24036681626275 6.24147122612731e-19 66.7901299494266 14.3732655228742 4.64683059275112 4.23522650600943e-06 -202.955656655957 34.5869976043493 -5.8679755605741 7.67848438575831e-09 CACTIN other 7.20078535358307e-15 0.000105364162741376 0.0391419633685391 4.64683059275112 -5.8679755605741 4.24997501664813e-08 37.8862085064208 18.6917238590482 2.02689750780162 0.0431565394462972 -246.607375437301 53.9080149855396 -4.57459573503962 5.90555923116091e-06 CCDC9 other 0.000315730643986789 0.0722663283117161 1 2.02689750780162 -4.57459573503962 4.93535849768241e-23 1308.3538956461 151.263799146065 8.64948456294364 5.78379224755406e-17 -1406.02871222402 482.351541064217 -2.91494603525447 0.00370347939860603 HNRNPUL1 other 6.18647187684491e-19 1 7.65831931498633e-13 8.64948456294364 -2.91494603525447 8.44127420143699e-26 101.507067324947 29.4255752160431 3.44962049440597 0.000604994161975231 -609.505515876401 70.6151885056027 -8.63136569872701 6.73102401316166e-17 FZR1 other 1.10335895086983e-21 1.0233848909611e-12 1 3.44962049440597 -8.63136569872701 3.52866619013542e-05 64.9729752537091 39.6010616074534 1.64068771432836 0.101438161167715 -437.785703145988 126.28026799518 -3.46677838189811 0.000568215262170305 TGFB1 other 0.2032511725518 1 1 1.64068771432836 -3.46677838189811 0.000163443465404232 27.2019379088414 6.92185236955179 3.92986392320337 9.60588785163034e-05 -55.7346270393338 53.9525498367931 -1.03303045375856 0.302052925553596 DENND3 other 0.863471827730557 1 0.795271455236476 3.92986392320337 -1.03303045375856 1.08183311006139e-16 229.18939818902 48.0684419408857 4.76798059048546 2.39118876093517e-06 -704.912348690241 130.269457020959 -5.41118666501259 9.39211452921582e-08 PLIN3 other 1.17789989023484e-12 0.00124426733283051 0.0225095441535529 4.76798059048546 -5.41118666501259 1.13471143028044e-07 688.788398513484 122.738043611315 5.61185740172565 3.18948121641953e-08 60.3499439418203 433.462035806616 0.139227749967807 0.889321613162851 MYH14 other 0.00081755958551706 1 0.000334193841856438 5.61185740172565 0.139227749967807 4.3026966874694e-31 343.912405292705 28.7735602588248 11.9523757991411 2.17745652067355e-29 -120.08519157943 105.650264894934 -1.13662934682512 0.256195549217843 MRPL4 essential 5.94890844009519e-27 1 3.19193351365535e-25 11.9523757991411 -1.13662934682512 0.0711112017170358 -5.33505151356926 3.62222393396715 -1.47286628624481 0.141361207115699 -30.0250062968105 14.8580134529928 -2.02079547119825 0.0437867476340184 SIGLEC8 other 1 1 1 -1.47286628624481 -2.02079547119825 0.692944779468552 -9.09072835719103 16.4393246221314 -0.55298672945193 0.580503480853065 -42.5841521961809 53.2955165986347 -0.799019409397597 0.424633732126234 CD79A og 1 1 1 -0.55298672945193 -0.799019409397597 0.000529442943677217 1782.96390472415 654.791488580618 2.72294911558648 0.00668142975717973 -3750.90045018291 2122.8031838554 -1.76695629567061 0.0778056423166765 RPS19 essential 1 1 1 2.72294911558648 -1.76695629567061 1.61088403102402e-07 -326.330761164556 228.647340459444 -1.42722307860142 0.154087232111615 -3655.15660471368 646.00353958329 -5.65810615692828 2.47302205859e-08 NOP53 other 0.00114888249092633 0.000333882708130236 1 -1.42722307860142 -5.65810615692828 0.167465594972279 11.0987265722378 8.37700115069203 1.32490450610967 0.185755011442073 54.0324290535623 34.2194624202347 1.57899701608439 0.114913762179846 NKG7 other 1 1 1 1.32490450610967 1.57899701608439 4.47520360884641e-07 19.1825923102392 3.55923772358019 5.38952264501839 1.05553095633595e-07 4.00274163890961 13.1676020815653 0.303984097796626 0.761256671812379 ICAM5 other 0.0030798351236081 1 0.00107600825688887 5.38952264501839 0.303984097796626 2.21402028858553e-05 222.692689229745 47.696655706412 4.66893718084741 3.81355774142679e-06 122.669864735613 192.616643183808 0.636860152414523 0.524482369570953 ETFB other 0.1300736919544 1 0.0353724831594472 4.66893718084741 0.636860152414523 0.0212276270123579 -4.90119225037259 2.92558137529984 -1.67528830055882 0.0944512863885964 -26.8303805750425 10.651377055046 -2.5189588572805 0.0120552730499761 CD33 other 1 1 1 -1.67528830055882 -2.5189588572805 0.193429519760686 560.040306399768 403.870512192021 1.38668283396114 0.166116017051293 -849.181043683926 1311.65407412005 -0.647412347843021 0.517642803975943 CEACAM5 other 1 1 1 1.38668283396114 -0.647412347843021 1.06777854552876e-33 431.482257162956 34.3507059488958 12.5610884913073 5.90727572473639e-32 -88.288000492019 121.557328567572 -0.726307508830623 0.467962657395649 BABAM1 other 1.50866430697759e-29 1 8.74158661746491e-28 12.5610884913073 -0.726307508830623 4.21244484500876e-32 254.222279715421 24.7255541331925 10.2817626794517 9.04699916809567e-23 -476.280887374729 93.496914567469 -5.09408133496252 4.84841808083788e-07 TYK2 other 5.87720304775622e-28 0.00624185343727069 1.2750840627514e-18 10.2817626794517 -5.09408133496252 6.25364725648882e-13 400.436542427631 137.273495342398 2.91707107354433 0.00367873043725686 -2255.53526180816 390.273504802987 -5.77937070810576 1.26147060667894e-08 NAPA essential 5.95034536454911e-09 0.000171963673102473 1 2.91707107354433 -5.77937070810576 9.62655620583693e-06 312.241143097936 90.7850123089157 3.4393468168013 0.00062851204319317 -625.317506845993 293.843934156339 -2.12805994665623 0.0337877305249143 RABAC1 other 0.0586449804059586 1 1 3.4393468168013 -2.12805994665623 0.465971884894488 17.4024018320677 23.2674793730782 0.747928108285047 0.454831540858369 88.4510411202418 75.3098722245293 1.174494638054 0.240718491382015 ATP1A3 other 1 1 1 0.747928108285047 1.174494638054 3.75041418565593e-07 -5.65479227465477 25.2605403900442 -0.223858721442217 0.822950819058968 -388.575264292336 73.4882473640777 -5.28758377332426 1.79454416364311e-07 MEIS3 other 0.00259941207207813 0.00234690485721246 1 -0.223858721442217 -5.28758377332426 5.15284712872612e-09 198.58123813217 50.8282280320402 3.90690853922731 0.000105261109702402 -427.169878446682 130.766230595328 -3.26666813367598 0.00115679152940849 PTPRS other 4.0563212597332e-05 1 0.867983110606007 3.90690853922731 -3.26666813367598 0.000161672244452043 18.8187583184924 6.10303313854955 3.08350911608598 0.00215171240104638 -32.9362301486344 19.3065118264328 -1.70596482910709 0.0885971895849778 CNFN other 0.855246173151306 1 1 3.08350911608598 -1.70596482910709 6.2917778859378e-14 128.635386358672 38.5264698012693 3.33888329302453 0.000899854030623216 -708.453910317656 122.504337434416 -5.78309246149699 1.24943344079508e-08 MEGF8 other 6.23829777390733e-10 0.000170335260983594 1 3.33888329302453 -5.78309246149699 3.48812078408405e-12 632.020070245865 106.794227026382 5.91811081782287 5.74970245655287e-09 -814.47201569129 323.528207018791 -2.51746833203939 0.0121047481960276 KDELR1 other 3.22755816151297e-08 1 6.21255350430537e-05 5.91811081782287 -2.51746833203939 1.66127616723432e-13 146.217081019368 61.6616699192588 2.37127994118271 0.0180732615840598 -1191.16617994715 186.726144804925 -6.37921476497878 3.80402119027916e-10 CYTH2 other 1.62107328398725e-09 5.3785055609357e-06 1 2.37127994118271 -6.37921476497878 8.0443928032137e-19 139.923460292646 20.6600054664516 6.77267295596115 3.27726378597526e-11 -264.005851334882 62.8721894146422 -4.19908792413388 3.12904545192613e-05 GRWD1 essential 9.25829167721865e-15 0.365535089694011 3.8288272811549e-07 6.77267295596115 -4.19908792413388 0.0031682973010068 42.2800396287861 14.3188665917388 2.95275043998101 0.00328484868534838 109.218741451377 43.3783488485953 2.51781693749078 0.0120929152065019 GRIN2D other 1 1 1 2.95275043998101 2.51781693749078 0.0353611381896721 -10.1834958753834 20.5738617644333 -0.494972504043358 0.620819748906325 -189.302358944546 73.0654788937525 -2.59085907340481 0.00983100149108339 CLEC11A other 1 1 1 -0.494972504043358 -2.59085907340481 0.0179241137969063 0.560460194249343 3.47673820384489 0.161202875048094 0.871993136776616 -28.0263562825284 10.532618744324 -2.66091054493279 0.00802184569468841 CCDC114 other 1 1 1 0.161202875048094 -2.66091054493279 1.35961016315406e-14 56.1993677588277 17.0842595851343 3.28954073068106 0.00106808252114594 -320.901128776886 51.7559799412813 -6.20027152690294 1.11144498540632e-09 CARD8 other 1.38149988678084e-10 1.55535611257761e-05 1 3.28954073068106 -6.20027152690294 3.50012381573395e-16 248.72900895945 31.5627525053172 7.8804600111333 1.77301345197622e-14 -111.966760690879 94.9945045149042 -1.17866566347858 0.239043792950791 LIG1 other 3.75353277999309e-12 1 2.2446350302019e-10 7.8804600111333 -1.17866566347858 0.0167921168241772 -2.83363090569181 1.19170477184757 -2.3777960553927 0.0177584634950853 -9.89276552482662 4.92776786562625 -2.00755510295723 0.0451810268058241 SIGLEC6 other 1 1 1 -2.3777960553927 -2.00755510295723 1.400192049886e-06 34.1672202090345 6.93888459931539 4.92402196923775 1.12385480634714e-06 -26.5590885965361 28.6926874504191 -0.925639630042677 0.355040734514262 ZNF175 other 0.00923286637694825 1 0.0107845107217072 4.92402196923775 -0.925639630042677 0.00549983334378232 10.9977248533874 11.8352022397853 0.929238438901993 0.353174660646181 -94.7621008003073 35.4588510765936 -2.67245265774727 0.00775412490360149 PLA2G4C other 1 1 1 0.929238438901993 -2.67245265774727 0.233128634288645 -1.32803889267489 1.31216821191308 -1.01209500475451 0.311940101387439 -8.21513315697126 5.34742294998854 -1.53627892048241 0.125048189055356 SIGLEC5 other 1 1 1 -1.01209500475451 -1.53627892048241 0.614552347515357 4.44538098051413 4.65757111192591 0.954441891210537 0.340281598903422 -1.82809190754435 19.211985947574 -0.09515371875312 0.924227577318785 HAS1 other 1 1 1 0.954441891210537 -0.09515371875312 8.74415885105109e-23 607.253470251982 68.845939794304 8.82046889135825 1.56128812274255e-17 -758.843285436069 232.180787286477 -3.2683293665456 0.00115041036507088 RAB3D other 1.09258264843883e-18 1 2.08431964386131e-13 8.82046889135825 -3.2683293665456 4.05711494351681e-06 55.7695323896781 18.5059239181474 3.01360432671989 0.00270212908467284 -182.894643983927 59.0143401659366 -3.09915595886802 0.00204125874511836 DBP other 0.0255719954889864 1 1 3.01360432671989 -3.09915595886802 9.4537893709005e-10 279.275576016308 76.0332071359084 3.67307373365307 0.00026342778555395 -1096.59456488392 256.419622500259 -4.27656258983383 2.2433729515464e-05 TMEM205 other 7.74738038945296e-06 0.264919911848115 1 3.67307373365307 -4.27656258983383 0.000101213505120111 583.25911197975 134.837155773751 4.32565570396951 1.81018949346455e-05 482.279792088401 321.714339180105 1.49909324314701 0.134430580749114 CAPS other 0.549690546307323 1 0.159622509533704 4.32565570396951 1.49909324314701 6.25470919380576e-11 95.699992958004 25.3963225301346 3.76826183572243 0.000182414657275867 -401.809217186789 85.6483065936126 -4.69138542450476 3.43978112265716e-06 PLPPR2 other 5.4516045333211e-07 0.0425879300796183 1 3.76826183572243 -4.69138542450476 0.018379815607011 -16.9464961941907 21.2927053726212 -0.795882716527935 0.426448637259768 -192.976729418336 68.0104988429737 -2.83745499152845 0.00471774825446465 FAM83E other 1 1 1 -0.795882716527935 -2.83745499152845 0.462905654748314 8.42779484294583 13.1633323879569 0.640247818299901 0.522280572935122 -36.2817656166699 41.6532923725089 -0.871041964515051 0.384114758093646 RASIP1 other 1 1 1 0.640247818299901 -0.871041964515051 1.8739413337467e-11 204.410697413736 38.4986576685346 5.309553885584 1.60266431560737e-07 -414.617921069814 121.826148295665 -3.40335738156606 0.000714562428690392 BCAT2 other 1.67511615823618e-07 1 0.00161708829444783 5.309553885584 -3.40335738156606 2.39529385936435e-15 49.1801473407022 16.0167320252741 3.07054817818622 0.00224924860137805 -156.908686816291 28.9462613727001 -5.42068921426502 9.13029362854634e-08 MIER2 other 2.50068678917638e-11 0.00121022042046382 1 3.07054817818622 -5.42068921426502 0.072655312985796 78.3052074879512 39.2372602389727 1.99568489265145 0.0464645633948494 -76.5506016819557 125.200093558818 -0.611426074102676 0.541172024288132 PLEKHA4 other 1 1 1 1.99568489265145 -0.611426074102676 1.33961169156215e-29 1823.80831681648 150.731948674732 12.0996798147426 5.39962283465983e-30 90.2857846476922 634.843342333421 0.142217423775508 0.886961216076416 PPP2R1A other 1.8256228132609e-25 1 7.93690560466649e-26 12.0996798147426 0.142217423775508 4.3773222362614e-22 407.977545540623 47.9473650431174 8.5088626908641 1.75870126264843e-16 -465.037978626612 147.447468899307 -3.15392310290649 0.00170102982731398 TNPO2 other 5.40292883621744e-18 1 2.30794366697353e-12 8.5088626908641 -3.15392310290649 1.0565278871989e-21 389.927609938869 56.5848559885324 6.891024164096 1.55449707173653e-11 -911.415173791154 171.764496810875 -5.30619068965507 1.63876316659347e-07 WDR83OS other 1.29435231460737e-17 0.00214809075877072 1.8343065446491e-07 6.891024164096 -5.30619068965507 1.16462531906841e-16 105.677445820597 16.5615726421825 6.38088230530934 3.8013426773638e-10 -207.609625803545 52.1508643131016 -3.98094314520092 7.80684608588723e-05 GCDH other 1.26711234714643e-12 0.886779646895931 4.30159937370488e-06 6.38088230530934 -3.98094314520092 0.401618327143691 8.08862467529222 6.35522769688398 1.27275135700616 0.203656023897253 -7.0892062490399 28.5453511289712 -0.248348889351896 0.803959241539058 LILRB5 other 1 1 1 1.27275135700616 -0.248348889351896 3.25214976040093e-16 312.784818930846 44.2386377372944 7.07039897539972 4.82098910152559e-12 -380.65075957869 137.444191122043 -2.76949325010537 0.00580820112054874 DNASE2 other 3.49053233783832e-12 1 5.76942788858279e-08 7.07039897539972 -2.76949325010537 2.46526488679375e-05 18.1633048607865 4.00719432194319 4.53267383648584 7.18296330368438e-06 29.3831752032037 12.4498766331589 2.36011778019911 0.0186251247984108 MAST1 other 0.144168690579698 1 0.0654008808800463 4.53267383648584 2.36011778019911 2.46092811977433e-12 65.7746337805924 9.52379825855288 6.9063447161455 1.43163713519992e-11 -64.5329098816867 38.8416387087362 -1.6614363355162 0.0972183163476636 LENG1 other 2.28989361545002e-08 1 1.69090662038463e-07 6.9063447161455 -1.6614363355162 6.48409285284108e-20 284.039160791312 29.8094256787867 9.52850161730701 5.75462946652296e-20 -73.9241403054858 120.554985290304 -0.613198534490066 0.540009118181533 PRPF31 essential 7.66549457062872e-16 1 7.9097382017358e-16 9.52850161730701 -0.613198534490066 9.57896305179269e-06 86.8855995141961 18.2480765566176 4.76135658706929 2.48714828207293e-06 -9.26007103139758 73.7986912114479 -0.125477442477478 0.90019334316215 TFPT other 0.0583658110511356 1 0.0233742195549214 4.76135658706929 -0.125477442477478 0.993211946111445 -0.678494420880256 12.7255903366242 -0.0533173238279995 0.957498795703874 -4.81621311421668 42.0139109700308 -0.114633772553385 0.908778019728119 JAK3 og 1 1 1 -0.0533173238279995 -0.114633772553385 1.08514241972462e-06 304.337263527749 92.7539009677261 3.28112629606429 0.00110031626808128 -949.310668217283 308.232633035933 -3.07985127618403 0.00217584593767405 RPL18A essential 0.00721511194874898 1 1 3.28112629606429 -3.07985127618403 0.0510655146897628 10.9933012918938 9.51287852117211 1.15562300805449 0.248343625790814 75.6719034955345 31.6124665781131 2.39373613281812 0.0170161285349063 SLC5A5 other 1 1 1 1.15562300805449 2.39373613281812 6.43605923961727e-06 78.715616980463 24.4748345122709 3.21618587210457 0.00137640321316896 -225.453455907132 83.0357442534729 -2.71513741382168 0.00683568458899468 ARRDC2 other 0.0397297936861574 1 1 3.21618587210457 -2.71513741382168 2.27139385957755e-08 500.759161885332 102.298705466305 4.89506841364939 1.2958221690051e-06 -783.709275870005 371.704557669665 -2.10841987190937 0.0354496415175506 PIK3R2 other 0.000172103512740191 1 0.0123919474021958 4.89506841364939 -2.10841987190937 4.73698199249915e-05 31.3667226639359 8.16915951816231 3.83965114087917 0.000137645021019116 -37.7512280223042 30.3574070436918 -1.24355904204766 0.214195563518232 RAB3A other 0.268776358254402 1 1 3.83965114087917 -1.24355904204766 5.3659878979344e-06 289.182397680863 66.7823403040633 4.33022257627093 1.77596892250409e-05 -291.112947289095 240.692879963648 -1.20947884845228 0.227008172405496 ISYNA1 other 0.0334086406525396 1 0.156693738032536 4.33022257627093 -1.20947884845228 2.08227588840136e-20 60.49434093908 8.83913960274953 6.84391735596783 2.0982464677503e-11 -162.322534372478 31.8574934286493 -5.09527012023182 4.82229195214125e-07 ELL other 2.48519627280702e-16 0.00620918311757707 2.46606907354693e-07 6.84391735596783 -5.09527012023182 1.50623974277537e-11 26.6180620389009 13.165747110734 2.02176616450419 0.0436940917547756 -267.294710174935 43.9133010026672 -6.08687354564167 2.18747765699687e-09 CRTC1 og 1.35230204106373e-07 3.04125018652275e-05 1 2.02176616450419 -6.08687354564167 0.628357981417099 140.91765987578 258.93023304396 0.54423022842549 0.586508529410139 -522.220066677973 855.21793950853 -0.610628054619713 0.541703712915719 COMP other 1 1 1 0.54423022842549 -0.610628054619713 0.0563088005817862 10.2861719991144 9.09210583445156 1.13132998959804 0.258413790817291 112.361197170465 49.095228229422 2.28863784165339 0.0224821886836577 UPK1A other 1 1 1 1.13132998959804 2.28863784165339 5.82818536341312e-10 474.090276830986 94.2301506324684 5.03119514984232 6.66230473299749e-07 -860.238883554973 315.898138179912 -2.72315274952664 0.00667697312887415 COPE essential 4.83389694041484e-06 1 0.00647975758331336 5.03119514984232 -2.72315274952664 4.27043597708926e-15 270.408619193436 35.0298323963166 7.71938090180155 5.77776518709305e-14 -108.214391836693 116.283299275419 -0.930609920005676 0.352475105207891 DDX49 essential 4.42203645427593e-11 1 7.23549534379662e-10 7.71938090180155 -0.930609920005676 0.000106352197376095 2.67206241309892 0.901099332690956 2.96533613571694 0.00315594205727727 -12.4594777611315 4.86572398092976 -2.56066267013171 0.0107155456005442 ETV2 other 0.575471740002049 1 1 2.96533613571694 -2.56066267013171 1.26227694719792e-14 153.769890097074 20.579328132253 7.47205589555072 3.27214350400486e-13 -79.8638722565123 67.0335705462682 -1.19140113835035 0.234028390467358 ARMC6 other 1.28474547685805e-10 1 4.02604536732758e-09 7.47205589555072 -1.19140113835035 2.9513112081465e-55 669.666078818585 38.1029456502209 17.5751787005135 3.93854205966654e-55 1.59704414232057 206.713022855655 0.00772589999535623 0.993838506952799 TMEM147 other 4.50252037914829e-51 1 6.06456706347454e-51 17.5751787005135 0.00772589999535623 6.5004673889505e-41 12.5544854916113 0.859654990112239 14.6040977322451 5.13775024278533e-41 -0.0970847828108777 4.6637308110067 -0.0208169782402002 0.983399259001167 GAPDHS other 9.55698715523503e-37 1 7.78009519264983e-37 14.6040977322451 -0.0208169782402002 0.435529808136788 -5.2953674728357 5.7166750587091 -0.926301988210513 0.354697562318625 -32.5362390294894 31.0350023548242 -1.04837237186263 0.294930066422067 MAG other 1 1 1 -0.926301988210513 -1.04837237186263 0.423797414823566 0.357750789500183 4.07372041787827 0.0878191807003073 0.930053070056912 -16.4117592790307 13.3438821088621 -1.22990889346446 0.219268771073294 TMEM59L other 1 1 1 0.0878191807003073 -1.22990889346446 0.782466622628867 -9.07566429832042 13.0032346594486 -0.69795435797398 0.485502317075243 -12.9025865824494 69.639362801762 -0.185277206214226 0.853080293174473 HAMP other 1 1 1 -0.69795435797398 -0.185277206214226 1.25922976775766e-19 348.888655845131 46.1787034707922 7.55518517460763 1.76934174742787e-13 -1148.97922044876 247.31196267236 -4.64586996938331 4.24731095798243e-06 USF2 other 1.48047643795268e-15 0.0523820860447973 2.19132975418942e-09 7.55518517460763 -4.64586996938331 9.51182807217258e-47 1444.62995860815 89.7967109914325 16.0877825329926 5.77593717171314e-48 1304.13894841659 483.819319070244 2.69550821352638 0.00724441929535351 LSR other 1.42619398900148e-42 1 8.83198552926656e-44 16.0877825329926 2.69550821352638 6.93161982075951e-20 289.37692962469 31.6634445918531 9.13914873617845 1.26758945906144e-18 -81.309399422225 104.252778423838 -0.779925491210055 0.435776436255754 KXD1 other 8.19040198020944e-16 1 1.71682316335281e-14 9.13914873617845 -0.779925491210055 2.01020547758727e-06 551.744541964529 143.352883920725 3.8488555435665 0.000132869042511644 -1080.71267435324 478.965128502425 -2.25634938754788 0.0244478618408534 FKBP8 other 0.0130703560152724 1 1 3.8488555435665 -2.25634938754788 1.14436699188556e-07 41.7874845362205 14.721643387794 2.83850677777369 0.00470667327235236 -185.485505336069 47.4365802148617 -3.91017869534274 0.000104229513141944 SUGP1 essential 0.000824173107555982 1 1 2.83850677777369 -3.91017869534274 0.000130448534500319 -69.9606839346446 44.4519467305938 -1.57384972043293 0.116101437505768 -995.392589872246 237.404784216869 -4.19280762666921 3.21417813805767e-05 HPN other 0.699073696387208 0.375223155836853 1 -1.57384972043293 -4.19280762666921 4.05224977915113e-06 8.46950351295293 7.00778788383627 1.20858445679958 0.227353452149661 -99.8376268304281 23.4290477290096 -4.26127548952022 2.39999775308176e-05 ZNF14 other 0.0255453826077687 0.282647735380439 1 1.20858445679958 -4.26127548952022 0.0260660599610468 -18.575376133082 9.98557845772645 -1.86022033793236 0.0633918301863883 -122.275700276394 53.3300400408695 -2.29281095950214 0.0222382087517812 SCN1B other 1 1 1 -1.86022033793236 -2.29281095950214 0.000302819882192805 6.3250072844631 1.68825236185619 3.74648211805782 0.00019900555208809 -1.63815369228403 5.35320075875298 -0.306013872094279 0.75971424830814 PBX4 other 1 1 1 3.74648211805782 -0.306013872094279 4.60554809650924e-10 140.383713972302 35.0119533054164 4.00959388777044 6.94858546334403e-05 -418.083776353903 111.504966152687 -3.74946328203365 0.000196564346097 ERF other 3.84425099615626e-06 1 0.582266649791952 4.00959388777044 -3.74946328203365 6.67082879088866e-24 274.383819400211 34.4278065229218 7.96983157255539 9.68025953039974e-15 -479.66424369354 109.64459387805 -4.37471859512779 1.46263659046689e-05 GSK3A other 8.47528797882404e-20 0.174843578024412 1.2325874460058e-10 7.96983157255539 -4.37471859512779 9.56034174256764e-13 268.802361020078 44.7445561926749 6.00748747764054 3.50790461969029e-09 -365.254186278472 140.26280125594 -2.60407023820939 0.00947128431323862 ATP13A1 other 9.0393031175977e-09 1 3.81940654991879e-05 6.00748747764054 -2.60407023820939 5.38833107880904e-17 68.5560417669917 12.3924425354801 5.53208470168109 4.95442166139532e-08 -192.031395533169 39.4753686087 -4.86458777463694 1.51000890218516e-06 ZNF574 essential 5.91584869142444e-13 0.0190170521141199 0.000514615777969132 5.53208470168109 -4.86458777463694 0.179975330792589 -3.98906874920015 5.88368837510772 -0.677987768026059 0.498072015891771 -35.2869340332807 19.0423224132487 -1.85307932863955 0.0644203709256239 GRIK5 other 1 1 1 -0.677987768026059 -1.85307932863955 5.42321243613021e-18 277.955966672449 38.9298066919783 7.13992671147077 3.00560599682532e-12 -1062.73334045112 234.853141214412 -4.52509740749383 7.41866899215739e-06 SIPA1L3 other 6.12009523417294e-14 0.0902926203035476 3.61604457478054e-08 7.13992671147077 -4.52509740749383 2.75071686711067e-06 17.4857887562488 5.44610514889561 3.21069613571355 0.00140246197162144 -52.116233341875 18.8377523239033 -2.76658448660803 0.00585771727124499 ZNF85 other 0.0176320951181794 1 1 3.21069613571355 -2.76658448660803 1.45304474042048e-05 50.8151454931372 21.5593367030905 2.35699020767429 0.0187764666324908 -224.112392920264 69.6963727353052 -3.21555317909304 0.00137909452475167 ETHE1 other 0.0871390930830159 1 1 2.35699020767429 -3.21555317909304 4.2650877816732e-11 128.475700813738 34.708890533771 3.7015213922996 0.000235975915227157 -501.048384766831 110.199906735513 -4.54672240303595 6.71117618018231e-06 CADM4 other 3.75071819520341e-07 0.0818830605744044 1 3.7015213922996 -4.54672240303595 4.40419175125162e-11 93.345165231739 19.0461083246413 4.90100988824955 1.2576001455067e-06 -193.37080795968 59.3981442760711 -3.25550251302347 0.00120181252909873 SMG9 other 3.8664399384238e-07 1 0.0120377485927902 4.90100988824955 -3.25550251302347 1.68841540696901e-14 289.30139748489 43.7906983979396 6.6064577197632 9.39022800932918e-11 -626.344686239597 185.795011530803 -3.37115986634418 0.000801687878553203 AVL9 other 1.70985828263752e-10 1 1.08259938719556e-06 6.6064577197632 -3.37115986634418 0.134337273017106 0.800353087640085 2.66100331518723 0.300771172689716 0.763703907153401 -15.9548193450401 8.66526593641168 -1.84123827960057 0.0661309391557474 RUNDC3B other 1 1 1 0.300771172689716 -1.84123827960057 0.00200833215395952 -1.94650565674392 11.3578700955006 -0.171379461146947 0.863989366823735 -126.792714434726 36.8300696738176 -3.44264117764791 0.000620561147866598 CFAP69 other 1 1 1 -0.171379461146947 -3.44264117764791 0.0206651606603819 197.998119095576 75.0384411045551 2.63862250042875 0.00856286040612144 -48.6452750432639 243.322337462487 -0.19992112335664 0.841616979759759 CDK6 og 1 1 1 2.63862250042875 -0.19992112335664 8.35330971608786e-30 182.643733401557 27.801869353483 6.56947671681203 1.18966470334267e-10 -659.264257842714 82.6941308591237 -7.97232223125756 9.33154574783103e-15 PMPCB essential 1.14122917341192e-25 1.398238814855e-10 1.3675195764924e-06 6.56947671681203 -7.97232223125756 2.84578174595843e-23 186.048914563807 23.2145821048793 8.01431245771608 6.85920390958346e-15 -295.493524838236 68.7543476519925 -4.2978158462634 2.04581664044821e-05 DNAJC2 other 3.58044406343064e-19 0.242388355560304 8.75303010901946e-11 8.01431245771608 -4.2978158462634 0.140546648945672 158.586739461107 111.108630063509 1.42731252622285 0.154066751268466 -334.890175575953 355.17186573209 -0.942896124065652 0.346154902626723 TFPI2 other 1 1 1 1.42731252622285 -0.942896124065652 1.7861115551518e-21 67.5751344217603 11.6037690899219 5.82355042556395 9.8889396583208e-09 -242.061051889043 37.0955858949156 -6.52533302950799 1.56195162825117e-10 BET1 other 2.1767341522635e-17 2.22390672830402e-06 0.000105870987981982 5.82355042556395 -6.52533302950799 2.33316007841193e-08 683.225428158297 126.650857857898 5.39455823445644 1.02782303005424e-07 -348.261174860372 386.059529935153 -0.902091899969081 0.367408752009012 NAMPT other 0.000176550223133431 1 0.00104848227295833 5.39455823445644 -0.902091899969081 7.18354005190266e-17 108.209756790553 12.8305566665312 8.43375385830455 3.0594979415675e-16 -47.8179417026149 54.810654351931 -0.872420558885924 0.383366015818197 TWISTNB essential 7.8595111707867e-13 1 3.99815191004041e-12 8.43375385830455 -0.872420558885924 0.112346635283719 -11.713216699406 6.09544515736151 -1.92163433465723 0.0551748521172037 3.47823441665995 18.0896536663054 0.19227755715073 0.84759668319405 PIK3CG other 1 1 1 -1.92163433465723 0.19227755715073 0.134764496103771 17.3745039328244 26.4831175194572 0.656059616850595 0.512066763037892 -139.33613680339 84.6006534892613 -1.64698653091464 0.100145831970726 PON3 other 1 1 1 0.656059616850595 -1.64698653091464 3.42489166271128e-06 63.0974273926182 54.4409120197882 1.15900753774447 0.246968233503438 -772.777933487477 173.912181224193 -4.44349514822814 1.07554351651389e-05 PON2 other 0.0217480620582166 0.129592238304758 1 1.15900753774447 -4.44349514822814 0.083444293892384 74.8893104039947 56.8390881710613 1.31756706192418 0.188204258877738 519.339764378347 252.23644496748 2.05894023143762 0.0399763406504581 ITGB8 other 1 1 1 1.31756706192418 2.05894023143762 8.150011194297e-11 3.94483005351788 55.0094190846457 0.0717119016917408 0.942857589110147 -1076.57784871737 163.25868504595 -6.59430674952673 1.01458407129301e-10 HBP1 other 7.06361470209721e-07 1.4501450130991e-06 1 0.0717119016917408 -6.59430674952673 3.31365002475043e-27 44.4009186098647 5.33627160295895 8.32058821467117 7.13790382236693e-16 -84.9375501165837 15.9765425166217 -5.31639120468125 1.54962690350618e-07 DUS4L other 4.40781726292302e-23 0.00203357538547116 9.27070948449016e-12 8.32058821467117 -5.31639120468125 0.0428808942896927 13.2675050794713 7.05290493226554 1.88114049556733 0.060487612921387 -36.6767580848114 31.872922509624 -1.15071839031193 0.250354589867254 SP4 other 1 1 1 1.88114049556733 -1.15071839031193 0.000151469514428548 39.1643886168139 12.7746372455024 3.06579262206469 0.00227833961166054 -72.6274750033525 41.5858741259634 -1.74644579511216 0.0812958645265624 WDR91 other 0.804151652101164 1 1 3.06579262206469 -1.74644579511216 8.60609833637553e-05 66.8499020447775 15.392123400342 4.34312409704903 1.67648250379575e-05 104.238000120692 69.558850021261 1.49855841620198 0.134569335065347 DNAH11 other 0.471528127850015 1 0.14823458298562 4.34312409704903 1.49855841620198 3.21697178143492e-15 81.2845742159323 22.4868652458086 3.61475791878475 0.000328656413872073 -414.961298346935 67.3246014063442 -6.16359086691648 1.38921258316304e-09 CBLL1 essential 3.34661574422675e-11 1.94031321490382e-05 1 3.61475791878475 -6.16359086691648 0.114797121637119 25.8769206926009 12.8239236312685 2.0178629752212 0.0441005093850106 1.70932473317996 40.3447050871495 0.0423680066439354 0.966221022235172 DLX5 other 1 1 1 2.0178629752212 0.0423680066439354 3.45377559675772e-14 585.823039609282 99.3888418389479 5.89425360805153 6.60067725327288e-09 -1070.78510899287 321.21863837406 -3.33350864823085 0.000915831097345632 MTPN other 3.45895626015286e-10 1 7.1188304176548e-05 5.89425360805153 -3.33350864823085 0.571981855325313 2.04867005297513 2.61898984280039 0.782236730931559 0.434417062384595 10.3496195239501 11.6770122831173 0.886324281675517 0.375835889723922 STEAP1B other 1 1 1 0.782236730931559 0.886324281675517 0.893401200696306 72.9318253779774 168.609855844724 0.43254781882467 0.665513783758271 174.739557771972 535.429800434886 0.326353814505739 0.744281501349838 PTN other 1 1 1 0.43254781882467 0.326353814505739 9.23214410992722e-06 28.0224140517449 7.59172633131741 3.69117811006263 0.000246010602416476 157.890040825268 41.2185440386639 3.83055841752109 0.00014295151136109 MPP6 other 0.0563437755028858 1 1 3.69117811006263 3.83055841752109 0.0490492407834301 51.9959865215243 25.4883897959458 2.03998710541514 0.0418314370625231 -46.6653504007419 75.3405198852341 -0.619392465990771 0.535915735071689 ATP6V0A4 other 1 1 1 2.03998710541514 -0.619392465990771 0.0298181939899258 37.4486763741122 36.1261140026409 1.03660959413942 0.300377549350492 -210.117409199895 107.38137030587 -1.95673987584054 0.0508882542139684 ZC3HAV1 other 1 1 1 1.03660959413942 -1.95673987584054 7.99231791116942e-13 38.1010317515681 9.55044562614447 3.98945067518797 7.52754813819962e-05 -136.482130891457 28.3855543079839 -4.80815450741679 1.97339662983469e-06 TTC26 other 7.57511891620637e-09 0.0247187661853093 0.629152473390724 3.98945067518797 -4.80815450741679 6.23352093553096e-12 473.734620816102 69.6042187949799 6.80611935623462 2.70175948055300e-11 -377.333851159624 273.419553345934 -1.38005437629479 0.168147394397803 OGDH essential 5.7080351206657e-08 1 3.16430070362368e-07 6.80611935623462 -1.38005437629479 5.13534162534825e-08 64.4685731651257 14.2888135823328 4.51182127848859 7.96292165960065e-06 -127.692776251636 51.5664139873445 -2.47627799526596 0.0135950127234895 ADAP1 other 0.000380169340524531 1 0.0722953657475143 4.51182127848859 -2.47627799526596 0.557639520503306 0.535203149846048 10.9392702281098 0.0489249409408296 0.96099723603536 34.9153623008114 33.634384377363 1.03808536850493 0.299695772187464 TFEC other 1 1 1 0.0489249409408296 1.03808536850493 2.19562418394392e-11 307.232930705658 59.4496588769735 5.16795111207371 3.34306391589751e-07 -896.183984742534 233.970097415628 -3.83033556271312 0.000143077578155978 H2AFV other 1.957398959986e-07 1 0.00331598509817874 5.16795111207371 -3.83033556271312 0.275752515569925 75.3802960623308 62.941055934753 1.19763316555211 0.231586260111056 -122.861179464831 195.236458645149 -0.629294243080576 0.529423063660233 CAV2 other 1 1 1 1.19763316555211 -0.629294243080576 0.705680705958276 173.045729118397 242.499797559574 0.713591231249936 0.475788269825488 -135.361093807604 747.532000765011 -0.181077323337433 0.856374825780403 CAV1 other 1 1 1 0.713591231249936 -0.181077323337433 0.00588390831010701 151.669983123301 50.8323121881549 2.98373173665398 0.00297660050730615 -28.8017200576499 156.67775519863 -0.183827755389629 0.854217715959463 MET other 1 1 1 2.98373173665398 -0.183827755389629 2.0420759477392e-17 19.6307970898278 2.62553596449228 7.47687228638817 3.08083598054935e-13 -19.9216561022154 8.21953434361464 -2.42369643697536 0.0156897379677327 RNF32 other 2.2683379627487e-13 1 3.79374142644847e-09 7.47687228638817 -2.42369643697536 8.83613930213991e-20 289.800400378025 41.7393090808095 6.94310487547736 1.10720278999886e-11 -498.977685059254 122.644313177622 -4.06849426713003 5.43933975213398e-05 LMBR1 other 1.04231099208042e-15 0.626068005470621 1.31225674670665e-07 6.94310487547736 -4.06849426713003 0.0339406296784231 -19.0801201590381 13.7449391071152 -1.38815603403882 0.165663011435808 70.4077700105005 42.557365543014 1.65442031272677 0.0986243102852862 WNT2 other 1 1 1 -1.38815603403882 1.65442031272677 0.332133330719058 1.0375943782327 0.841676381964995 1.23277117009071 0.218202577185167 4.33732692038209 4.29379980079905 1.01013720285118 0.312886188494743 HOXA1 other 1 1 1 1.23277117009071 1.01013720285118 5.660680632778e-19 310.461602729857 54.5654012745467 5.68971537784108 2.09576308714231e-08 -859.087233429783 161.286954809961 -5.32645206453316 1.47640039798622e-07 DNAJB6 other 6.53921826698515e-15 0.00193999012295389 0.000221396412525713 5.68971537784108 -5.32645206453316 0.248877962297664 -2.52354426756386 1.67020455904506 -1.51091927865812 0.131401630776196 -7.94916275209147 8.50699122796484 -0.934427054063529 0.350506778488586 HOXA2 other 1 1 1 -1.51091927865812 -0.934427054063529 0.941986802611684 -1.26976145826261 6.00733668824849 -0.211368452303748 0.832682108366496 5.84146393287384 25.1316658581501 0.232434410271274 0.816291551564698 HOXA3 other 1 1 1 -0.211368452303748 0.232434410271274 0.00226816881685679 120.231521309475 96.1956826884411 1.24986400583986 0.211897740502879 -929.367260482102 327.336852481568 -2.83917699286374 0.00469563145691356 LFNG other 1 1 1 1.24986400583986 -2.83917699286374 0.227504274397923 -14.421745251491 8.50217777843761 -1.69624131926129 0.0904341242424066 -21.1741429119716 35.577308767405 -0.595158645933636 0.551994358143989 HOXA5 other 1 1 1 -1.69624131926129 -0.595158645933636 0.449993366708069 -1.80278222640525 1.42629823917553 -1.26395881091976 0.206807862566573 -1.06325752224005 5.96691223103036 -0.178192251045806 0.858640993873924 HOXA6 other 1 1 1 -1.26395881091976 -0.178192251045806 4.97495975663164e-13 209.567907181709 40.7326341201868 5.14496328824089 3.76227625098854e-07 -586.951755543256 138.873114250323 -4.22653267849425 2.79049200528788e-05 BRAT1 essential 4.75307655148587e-09 0.32724099746011 0.00371976252935237 5.14496328824089 -4.22653267849425 2.54398106929733e-12 140.452503826987 33.7573199372618 4.1606532772157 3.6948199950156e-05 -570.535166758947 115.708873433412 -4.93078145028589 1.09339715196305e-06 IQCE other 2.36539359823266e-08 0.0138620890925876 0.317791467771292 4.1606532772157 -4.93078145028589 0.0817895294777455 13.328961010837 24.7957342521721 0.537550567177472 0.591112989124302 -138.787433995431 73.6281660007839 -1.8849774690022 0.0599797140379374 VIPR2 other 1 1 1 0.537550567177472 -1.8849774690022 0.0265755695283235 39.8925517534816 26.2776048489185 1.51811978233334 0.129565116482289 -136.255367293776 82.47156254479 -1.65214969971954 0.099081066623013 TSPAN12 other 1 1 1 1.51811978233334 -1.65214969971954 4.94910536151041e-25 317.361075104543 33.1831526581374 9.56392173986873 3.90436262476441e-20 -273.720098560068 112.391949202594 -2.43540663278887 0.0151952265124964 SSBP1 essential 6.39622376921605e-21 1 5.37747864308802e-16 9.56392173986873 -2.43540663278887 0.614093568607525 2.38628380960411 3.13938553783374 0.760111741882684 0.447529649005466 -6.4344553274149 13.1565661370415 -0.489067987831498 0.624998203492693 HOXA13 other 1 1 1 0.760111741882684 -0.489067987831498 0.802747314839048 24.0887789193541 37.5306179700247 0.641843386074632 0.521244735370667 42.2359320174201 117.306508724935 0.360047643361859 0.7189509880526 CPED1 other 1 1 1 0.641843386074632 0.360047643361859 2.66876146311572e-13 190.870207332851 28.257621988202 6.75464507992011 3.73163293562697e-11 -313.234546491276 117.702149281663 -2.66124746576802 0.00801821423396495 HIBADH other 2.5828273440034e-09 1 4.35071083964748e-07 6.75464507992011 -2.66124746576802 8.2057306072314e-19 584.571263897612 77.3955757887273 7.55303204272763 1.83699731432695e-13 -1353.11798102785 319.879723866206 -4.23008362228615 2.74577697777236e-05 TAX1BP1 other 9.44069306361973e-15 0.322079639492697 2.27457007459963e-09 7.55303204272763 -4.23008362228615 0.229855855901757 21.9897381806844 19.9991197306846 1.09953530339366 0.272025498896922 122.446069193232 80.9268646310768 1.51304600457993 0.130854079631806 CPVL other 1 1 1 1.09953530339366 1.51304600457993 0.126935694104706 85.081940671939 46.9875416631535 1.8107340299239 0.0707376438067131 -97.5813192379325 188.468831701337 -0.517758391968852 0.604838892935848 GRB10 other 1 1 1 1.8107340299239 -0.517758391968852 2.98445179859718e-08 260.546678136408 56.6910107697249 4.59590814485089 5.38943996946866e-06 -573.854455863307 212.865388010427 -2.69585610524525 0.00724351746294351 ABHD11 essential 0.000224400930736522 1 0.049518174439478 4.59590814485089 -2.69585610524525 0.124691705989681 41.7438088501511 74.6948207235398 0.558858143654339 0.576490210878532 -539.230002304675 299.603790656401 -1.79981034660235 0.0724486390313373 COBL other 1 1 1 0.558858143654339 -1.79981034660235 0.000677626501154472 53.2330353187549 14.8251288441839 3.59073002860537 0.000359940842895418 -38.5992710724496 62.2101797343353 -0.620465512835446 0.535214089022575 FKBP14 other 1 1 1 3.59073002860537 -0.620465512835446 1.69775412167033e-16 94.6772788397394 11.0439330572008 8.57278637505034 1.07622980054146e-16 -12.9818420347634 46.3432775312416 -0.280123520094407 0.779490413752772 PLEKHA8 other 1.83595130717429e-12 1 1.41771751625326e-12 8.57278637505034 -0.280123520094407 6.12225640042283e-05 54.0192014574858 14.5774695125778 3.70566382669342 0.000232953652816867 -85.1308875093223 54.7359918596155 -1.55529998849134 0.120470422329738 STX1A other 0.342050465091623 1 1 3.70566382669342 -1.55529998849134 1.40216228335276e-06 34.0417766262829 7.68903424339139 4.4273149980495 1.15475196742125e-05 -58.9290622103125 32.0939822494671 -1.83614054972225 0.0668854463086825 NOD1 other 0.00924445593414474 1 0.103569703958012 4.4273149980495 -1.83614054972225 6.28542896247338e-19 709.124337014755 74.5001297446344 9.51843089999218 5.75157277282593e-20 692.186864507467 311.033300220085 2.22544294780553 0.0264621754845131 GARS essential 7.25087085110929e-15 1 7.90611193352653e-16 9.51843089999218 2.22544294780553 0.945778950132837 -7.43649277994219 23.1839983294759 -0.320759718589503 0.748515442079298 -14.709268588761 81.8510147505699 -0.179707834210554 0.857448737076379 EPHB6 other 1 1 1 -0.320759718589503 -0.179707834210554 0.117238211157628 18.177601416597 8.76346725768006 2.07424765587692 0.0385269411916934 17.4597012454845 36.7380748432216 0.475248126636824 0.634801234315713 MINDY4 other 1 1 1 2.07424765587692 0.475248126636824 8.84320408226563e-16 251.850910295183 36.3419962166444 6.93002411848353 1.19009536582689e-11 -304.099408826602 118.032658887924 -2.57640056313019 0.0102450570379005 CASP2 other 9.36760608434398e-12 1 1.40942994174878e-07 6.93002411848353 -2.57640056313019 2.60386423519607e-10 570.706753264344 91.6515906427805 6.22691596798052 9.80258882111669e-10 -591.089411019753 395.980360372806 -1.49272405950451 0.136114722732319 CHCHD2 other 2.20208798370532e-06 1 1.09220444644882e-05 6.22691596798052 -1.49272405950451 0.000578992283895686 3055.24000813089 1057.02806563399 2.89040575880868 0.00400337040730467 -6777.96860277579 3636.05201830778 -1.86410110984338 0.062853972528106 HSPB1 other 1 1 1 2.89040575880868 -1.86410110984338 0.00104453475302708 52.3005415251275 17.8885752401982 2.92368401747282 0.00360401567028384 169.578912297263 55.3974196210459 3.0611337758562 0.00231449140907219 NPTX2 other 1 1 1 2.92368401747282 3.0611337758562 1.24147993296526e-19 394.217940076942 55.23659209975 7.13689829678552 3.08550983528398e-12 -753.77409655619 175.136877949603 -4.30391420345574 1.99209663591074e-05 PDAP1 essential 1.45973210518056e-15 0.236123214254501 3.70970847496193e-08 7.13689829678552 -4.30391420345574 1.67721547495063e-18 249.774461715771 38.7714316418798 6.44222952670056 2.60818786801354e-10 -582.157148590202 122.910687955216 -4.73642413263784 2.78397646513093e-06 BUD31 essential 1.91638640167859e-14 0.034638235179159 2.96577042471819e-06 6.44222952670056 -4.73642413263784 1.87606252563128e-22 215.563622660998 31.1859168422023 6.9122105260438 1.3504866986047e-11 -553.265455586191 98.8635789618055 -5.59625153566347 3.48734783091204e-08 PTCD1 other 2.33100768809687e-18 0.000468385687169796 1.59627527775076e-07 6.9122105260438 -5.59625153566347 0.86176753185258 1.80292625664831 3.48992213541862 0.516609307225144 0.605642790769731 3.44096959002565 11.1152159407865 0.309572896141338 0.757006531202894 CYP3A5 other 1 1 1 0.516609307225144 0.309572896141338 1.00906272490249e-08 221.064867283606 136.245299687801 1.62255041304298 0.105271352035795 -2275.93840781449 431.850777902781 -5.27019638326751 1.97572537319776e-07 ZKSCAN1 other 7.80005486349625e-05 0.00257911190217236 1 1.62255041304298 -5.27019638326751 5.27842832208783e-13 983.252904583428 137.447566363314 7.15365815924599 2.81250841719937e-12 -438.781685514537 467.617743493275 -0.938334123587095 0.348498528575975 EIF3B essential 5.03562061927179e-09 1 3.38541638178288e-08 7.15365815924599 -0.938334123587095 3.91458230061193e-07 75.7378089004443 15.2705278842603 4.95973744159227 9.51066615711449e-07 -52.7162872609521 51.9526826129011 -1.01469807928381 0.310711018253017 NUDT1 other 0.00270693366087315 1 0.00916352684237981 4.95973744159227 -1.01469807928381 0.709546096330542 27.1803848432583 42.9741415652049 0.632482322003277 0.527337498775131 -42.1598023710529 136.159360805019 -0.309635724799164 0.756956553761975 PTPRZ1 other 1 1 1 0.632482322003277 -0.309635724799164 2.68780804254375e-23 190.980148938645 31.9916196893521 5.96969302564601 4.32749663575028e-09 -696.768864782876 101.92752528962 -6.83592447479769 2.22439945547731e-11 TAF6 essential 3.38287520234556e-19 3.21447965311027e-07 4.69490110012547e-05 5.96969302564601 -6.83592447479769 2.63552096959861e-21 217.36742907736 49.1056861423891 4.42652259143823 1.15845244728522e-05 -1071.76758770798 149.869470836502 -7.15134030784168 2.7971632236528e-12 WASL other 3.20242153015927e-17 4.09169036355931e-08 0.103878430948065 4.42652259143823 -7.15134030784168 2.83680697906791e-18 152.108542390927 17.7794346615739 8.55530815722025 1.20569011344063e-16 -81.6520378162789 62.3569486930125 -1.30942965503744 0.19094263270775 AIMP2 other 3.22374745101278e-14 1 1.58668818928787e-12 8.55530815722025 -1.30942965503744 0.00240114597990625 27.1151611332004 9.36630953720703 2.89496743893497 0.00394453437808629 -30.528213153104 29.9675268551196 -1.01870979546277 0.308794425034797 TFR2 other 1 1 1 2.89496743893497 -1.01870979546277 3.48118831339251e-12 139.199074034144 30.0710907128579 4.6289998378617 4.59966807566262e-06 -366.111649575588 92.7555785065141 -3.94705801495138 8.94971554823352e-05 FSCN3 other 3.22149166521343e-08 1 0.0424319379979877 4.6289998378617 -3.94705801495138 1.39919955308021e-18 69.6336330811468 13.1341049751081 5.30174177936884 1.6715103669731e-07 -247.546072470422 42.0225961992796 -5.8907848362464 6.74562045873338e-09 MOSPD3 other 1.60082420867906e-14 9.26713338620791e-05 0.00168488244990888 5.30174177936884 -5.8907848362464 0.226465632783154 -149.85401207443 91.7073284319576 -1.6340462058669 0.102829824645732 -296.318786270162 293.403118959387 -1.00993741075799 0.312975922834743 PCOLCE other 1 1 1 -1.6340462058669 -1.00993741075799 3.50341687570302e-11 3.21476936375056 0.900040632771122 3.57180470158626 0.000386147260022006 -13.8481035059037 2.87463132172193 -4.81734941147464 1.89172254280133e-06 FBXO24 other 3.09176539280792e-07 0.023718417241643 1 3.57180470158626 -4.81734941147464 4.70782331875335e-42 259.679426828424 18.7236518505846 13.8690587125137 1.19498893791517e-37 -109.603606997016 67.1204822692591 -1.63293831169646 0.103062730232333 RBM28 essential 6.95675051812182e-38 1 1.79654636926167e-33 13.8690587125137 -1.63293831169646 6.75362357689949e-08 32.0036275778995 10.2483303717691 3.1228138064381 0.0018874971277538 -144.504385630915 36.4483747821215 -3.96463179756912 8.34205535596003e-05 USP42 other 0.000494635390772118 0.945655395151629 1 3.1228138064381 -3.96463179756912 3.55421704624272e-29 501.624733247969 48.0564169985172 10.4382466396412 2.31015511767662e-23 -504.744398207423 173.232220517359 -2.91368659190537 0.00371958525412414 IMPDH1 other 4.82769301391149e-25 1 3.27395183277131e-19 10.4382466396412 -2.91368659190537 8.44502395999017e-05 33.1459157794952 17.9779899709985 1.84369419679091 0.0657744140049033 -186.470256560619 57.419733277061 -3.24749430062422 0.00123642247217388 AGFG2 other 0.463336829723367 1 1 1.84369419679091 -3.24749430062422 1.68358648192605e-16 137.576697847032 16.8091357041716 8.18463841736308 1.94188829248847e-15 -104.276762533225 70.5694650733966 -1.47764705917455 0.140079908620525 LSM5 essential 1.82079878020303e-12 1 2.50251144252989e-11 8.18463841736308 -1.47764705917455 0.706381938969168 -51.6756073191496 113.249537605367 -0.456298616416607 0.648359060747477 173.957088536921 334.751299384023 0.519660681995918 0.603513431397646 SERPINE1 other 1 1 1 -0.456298616416607 0.519660681995918 1.20138076149992e-18 237.775710434748 37.6748249603844 6.31126251242767 5.77483044542516e-10 -522.453242339555 111.172338600018 -4.69948953956314 3.31406227066251e-06 AP1S1 other 1.37678235267891e-14 0.0410778018448618 6.48975445456879e-06 6.31126251242767 -4.69948953956314 0.000141421309258588 128.737206571029 31.0372163051464 4.14783353330829 3.89258665541903e-05 217.230814184794 111.639189968315 1.94582936553416 0.0521889154344756 C1GALT1 other 0.753131357100755 1 0.334061786768061 4.14783353330829 1.94582936553416 9.10262853176372e-07 337.504963552806 74.764461080239 4.51424324707681 7.80591212600435e-06 -288.211516276839 220.205968265827 -1.30882699749953 0.191149674915181 PLOD3 other 0.00610695348196028 1 0.0709089057526235 4.51424324707681 -1.30882699749953 9.43250831321764e-17 104.542243808127 14.723052267879 7.10058226419565 3.89469150755525e-12 -176.229164149213 52.9580234543981 -3.32771415271877 0.000934700819416248 RPA3 essential 1.02833205630699e-12 1 4.67090352501101e-08 7.10058226419565 -3.32771415271877 1.672417447771e-10 241.523093501857 60.6706398179503 3.9808891784655 7.80310181430608e-05 -720.162719173724 177.586707325861 -4.05527378720002 5.74375176693084e-05 ZNHIT1 other 1.42908070912032e-06 0.659497577878999 0.651324908440128 3.9808891784655 -4.05527378720002 8.55523752726133e-06 11.7921068640341 5.03928284885883 2.34003671111744 0.0196437865341042 -49.2783809860866 14.7516824060925 -3.34052616030661 0.000893775976598986 CLDN15 other 0.0523152774792031 1 1 2.34003671111744 -3.34052616030661 2.20852402410157e-05 -14.4118245669816 23.7679504390964 -0.606355377755891 0.544532196154659 -398.77178618506 85.9451329054109 -4.63984140467778 4.3753367508443e-06 GLCCI1 other 0.129794956896449 0.0539216501174052 1 -0.606355377755891 -4.63984140467778 7.64341421151981e-10 105.327185946781 25.2052165006114 4.17878521076087 3.41510366315175e-05 -359.726045109544 91.4487101766586 -3.93363716573621 9.45202574860499e-05 PHF14 other 6.29435160318656e-06 1 0.29458684198347 4.17878521076087 -3.93363716573621 2.96548600346553e-11 15.1218822460054 4.99315421659804 3.02852297165946 0.00257369179535472 -97.6347082482525 18.4134794844974 -5.30234974494922 1.66289155269152e-07 NRF1 essential 2.62801369627115e-07 0.0021788868014917 1 3.02852297165946 -5.30234974494922 6.18545326002097e-08 103.108022414583 57.5847118789635 1.79054507785512 0.0739222531977778 -1027.27026227226 207.391525121148 -4.95328949277064 9.75479935593215e-07 TMEM106B other 0.000454692669144142 0.0123973745014542 1 1.79054507785512 -4.95328949277064 9.37820676511421e-07 157.134967218072 30.9371272298283 5.07917125112281 5.24423758531042e-07 7.09592478867346 96.3572114042726 0.0736418653597401 0.941322882369001 EZH2 other 0.00627964724992048 1 0.00513568186729449 5.07917125112281 0.0736418653597401 3.21643113776132e-20 70.7496550462817 9.71383637721858 7.28338962062484 1.15129245694708e-12 -128.710667579366 32.1688373657463 -4.00109789844063 7.1798586087843e-05 CEP41 other 3.82497990902576e-16 0.81814488847097 1.39743878424236e-08 7.28338962062484 -4.00109789844063 8.19881626552751e-14 76.1097567846575 18.7528169162059 4.05857728600148 5.66408042677136e-05 -297.252298307339 57.9371158603654 -5.13060227270803 4.02933392034084e-07 ZNF862 other 8.0914117724491e-10 0.00520066129098393 0.479011281692054 4.05857728600148 -5.13060227270803 0.416704157387518 -110.89198848372 149.878803535365 -0.739877726989956 0.459691609361758 -720.035771672776 577.551481604114 -1.24670405081971 0.213039619310777 SFRP4 other 1 1 1 -0.739877726989956 -1.24670405081971 3.81169008443842e-06 525.346816638342 116.506293337895 4.50917114936199 7.97615594925643e-06 -279.666827980777 385.880818937284 -0.724749234105442 0.468917485710611 MEST other 0.0241013164039041 1 0.0723995675514006 4.50917114936199 -0.724749234105442 0.813675618234205 6.7105426943945 10.4527795502415 0.641986436444026 0.521156450234478 6.89211846099032 38.2019351246777 0.180412809940043 0.856896688572546 MEOX2 other 1 1 1 0.641986436444026 0.180412809940043 9.9570862951367e-09 19.2172959187623 12.061745130509 1.59324340804996 0.111696197337582 -239.297520022755 44.4951584616787 -5.37805748526212 1.12700790013423e-07 ANKMY2 other 7.69782341477018e-05 0.00148855332387074 1 1.59324340804996 -5.37805748526212 1.47513732904086e-06 13.1437417344046 3.44982572090518 3.80997267623012 0.000154805682589558 -22.7255489460151 10.6594993870474 -2.13195274194859 0.0334572715638835 ACTR3C other 0.00969736042618505 1 1 3.80997267623012 -2.13195274194859 1.80169101028441e-06 780.524446773192 371.257046547022 2.10238284776727 0.035985590788064 -5598.72903039384 1369.86770219992 -4.08705820379782 5.03802828971815e-05 TSPAN13 other 0.0117632406061469 0.581086182936092 1 2.10238284776727 -4.08705820379782 0.873522760223606 -27.1177938187088 60.9784752535068 -0.444710919811811 0.656705228425919 -75.6964313382997 188.126826872316 -0.402369149561406 0.68757013457411 RARRES2 other 1 1 1 -0.444710919811811 -0.402369149561406 0.00535842611311213 408.616234391315 1296.96497802358 0.315055719556897 0.752841962122066 -14609.7781680643 4785.55343475186 -3.05289207763739 0.0023789405440518 AGR2 other 1 1 1 0.315055719556897 -3.05289207763739 0.175616811652783 -45.3596097233485 67.1810794038051 -0.675184294832562 0.499849835440799 -459.934907551861 247.885371416229 -1.8554338439745 0.0640830642576046 AHR other 1 1 1 -0.675184294832562 -1.8554338439745 0.00213627558993764 164.061545219694 48.8756541911679 3.35671302890388 0.000843654968900551 14.0459253768767 160.918742086441 0.0872858263416675 0.930476321644395 CHCHD3 other 1 1 1 3.35671302890388 0.0872858263416675 0.623863659996753 6.6022257221129 8.69844489799828 0.759012191205836 0.44817400510846 -8.64748143759443 27.0616950407043 -0.319546925075738 0.749434489894595 GIMAP2 other 1 1 1 0.759012191205836 -0.319546925075738 0.607165293460778 -19.8201396842504 101.514916584472 -0.195243618879968 0.845274865777114 -311.203145220041 314.688138854159 -0.988925564062225 0.323137597856963 TMEM176B other 1 1 1 -0.195243618879968 -0.988925564062225 5.37746641030557e-07 -251.960402458322 81.183817380379 -3.10357914407726 0.0020105988875312 -1603.39169690183 316.639584576455 -5.06377526690657 5.62341842565811e-07 GLI3 other 0.0036728095582387 0.00721990691670245 1 -3.10357914407726 -5.06377526690657 5.5215157685681e-24 439.782940156246 43.3172653651797 10.1526016577621 2.62665778820014e-22 -252.61219304804 169.768294835506 -1.48798215410482 0.137330786705224 PSMA2 other 7.02281590604177e-20 1 3.68546354262361e-18 10.1526016577621 -1.48798215410482 5.22740425990805e-17 105.899284924318 14.9841110569327 7.0674386035948 4.82071180529979e-12 -219.506736065105 58.4422222729985 -3.75596148688072 0.000191159591344863 MRPL32 essential 5.74282631993498e-13 1 5.76942788858279e-08 7.0674386035948 -3.75596148688072 3.65555042191223e-15 105.185747737774 16.5737365647131 6.34653189563319 4.63153745496451e-10 -255.904049278782 64.5612300414019 -3.96374184808244 8.35903458883423e-05 COA1 other 3.79446133794489e-11 0.94749657064436 5.22298478796347e-06 6.34653189563319 -3.96374184808244 9.05128661668938e-07 205.20962945438 63.2803217784578 3.24286640281021 0.00125560803491424 -842.523765880522 246.501770767325 -3.41792175876816 0.000678073553156936 BLVRA other 0.00607522357712191 1 1 3.24286640281021 -3.41792175876816 1.01168513333686e-22 90.3212188345922 16.3179026032479 5.5350997631653 4.84351409022087e-08 -485.001998799711 64.3671756935633 -7.53492744669565 2.05189442906745e-13 URGCP other 1.26288655194441e-18 3.03618818669111e-09 0.00050328954911485 5.5350997631653 -7.53492744669565 1.61806026419585e-17 168.520804605122 52.0171024557827 3.2397191817513 0.00127195278913433 -1467.10395589849 191.336398283284 -7.66766788264905 8.50054342384656e-14 TMEM248 other 1.80171010418208e-13 1.26369078538903e-09 1 3.2397191817513 -7.66766788264905 4.18192074829436e-08 24.8839716831762 5.60436790764586 4.44010316475258 1.09596228302622e-05 -58.5111448423864 20.4212484592832 -2.86520899831606 0.0043336980348663 STAG3L4 other 0.000310912036442791 1 0.0984283726385844 4.44010316475258 -2.86520899831606 2.47020221467027e-19 253.550158896842 31.7429369253278 7.9876086920783 8.20056270437779e-15 -236.110171766498 97.6967989008069 -2.41676466806476 0.0159859479648507 RHEB other 2.884208105849e-15 1 1.04524372229999e-10 7.9876086920783 -2.41676466806476 1.20760114362477e-13 60.8847756793643 15.3256148000538 3.97274605121555 8.05773056066816e-05 -238.230958969386 46.7448962340512 -5.09640577179947 4.7781664519152e-07 PRKAG2 other 1.18453596178154e-09 0.0061528449401312 0.671611842231691 3.97274605121555 -5.09640577179947 3.61135308834185e-12 459.140466522299 63.675793072971 7.21059674900531 1.9154849665561e-12 -102.105688794345 252.766388094938 -0.403952794372307 0.68640915314545 POLD2 essential 3.3372513889367e-08 1 2.31524667907635e-08 7.21059674900531 -0.403952794372307 0.0978309707718105 -9.29374759167422 4.48199083659302 -2.07357576811533 0.0385975526913638 -17.7821382403466 17.7916376155999 -0.999466076397317 0.31802163928512 MYL7 other 1 1 1 -2.07357576811533 -0.999466076397317 4.57434791969302e-19 132.606466921074 18.3183336535013 7.23900270785426 1.60112481907055e-12 -311.439878557464 68.8794140109728 -4.52152334669761 7.58341648471329e-06 BCL7B other 5.29892463017239e-15 0.0922370947035677 1.93912226837635e-08 7.23900270785426 -4.52152334669761 4.24812546295415e-18 475.876504992419 53.0248336904075 8.97459684213037 4.83054626993313e-18 -128.297031365134 210.486513703876 -0.609526135938708 0.542435004338709 YKT6 essential 4.80547952369374e-14 1 6.49660167843307e-14 8.97459684213037 -0.609526135938708 1.57295673625508e-15 186.281624877597 28.5831769786887 6.51717704496201 1.67237293324525e-10 -423.734784069279 107.476614309168 -3.94257659485218 9.14507686784883e-05 TBL2 other 1.65144727739421e-11 1 1.91302739833925e-06 6.51717704496201 -3.94257659485218 0.320233519798679 20.7903967599168 18.810328747107 1.10526493393234 0.26954160205578 -52.1304717044784 69.4865901180049 -0.75022348363833 0.453449916663564 CLIP2 other 1 1 1 1.10526493393234 -0.75022348363833 1.05276852505291e-21 521.764331593296 79.8468127372899 6.53456679992967 1.49069061225659e-10 -1840.05750006845 294.424043316943 -6.24968490799393 8.41665566281300e-10 EIF4H other 1.28995727374733e-17 1.18110928916255e-05 1.70766308671377e-06 6.53456679992967 -6.24968490799393 1.08293209372939e-06 136.544072519406 34.4465038735646 3.96394574673207 8.37511490688808e-05 -322.015605390608 127.016703621674 -2.53522250388224 0.0115218079463571 LIMK1 other 0.00720149842330047 1 0.697144564849363 3.96394574673207 -2.53522250388224 2.9805889174962e-19 -6.03459600107606 3.98540957001425 -1.514172105793 0.130564029014583 -90.7432718425572 9.70589963517496 -9.34929014861191 2.28656876561151e-19 SPATA6L other 3.47089579442433e-15 3.51239828085585e-15 1 -1.514172105793 -9.34929014861191 0.000538846326152942 -254.062316247801 188.754199582004 -1.34599556889554 0.178865617916917 -1794.3937742672 459.684076297875 -3.90353694371704 0.000106721027817452 SLC1A1 other 1 1 1 -1.34599556889554 -3.90353694371704 0.224152736915044 9.66970556889537 5.65237698429167 1.71073259900536 0.0877005923221225 10.0423911602091 12.850793151906 0.781460804909121 0.434871478671857 LHX2 other 1 1 1 1.71073259900536 0.781460804909121 5.70754347532497e-17 101.142923947534 22.7148890401605 4.45271485890646 1.02868437833599e-05 -275.647915341153 48.1374881241669 -5.72626296224973 1.69647714008709e-08 FKTN other 6.26288745547409e-13 0.000230178018367016 0.0926227414253726 4.45271485890646 -5.72626296224973 0.000239996717542764 34.3519510397686 12.8578388055544 2.67167379831587 0.00777232032955472 -54.6096059855446 27.3350402884469 -1.99778765311077 0.0462343900982642 FSD1L other 1 1 1 2.67167379831587 -1.99778765311077 2.84484792515779e-07 30.6798277781589 5.56957068402067 5.50847264874125 5.77978605954062e-08 13.803420517123 16.4966143876122 0.836742630505343 0.403133806857654 CNTNAP3 other 0.00198769524530775 1 0.000598323452883645 5.50847264874125 0.836742630505343 4.50523519815894e-16 250.126981290181 84.4031129058234 2.96348052434122 0.00317546821616094 -1284.136791552 190.617849502528 -6.73670799929451 4.14723521736294e-11 SPIN1 other 4.81249223867338e-12 5.96579786017659e-07 1 2.96348052434122 -6.73670799929451 4.03234328847298e-13 30.7708304675295 13.4684186352986 2.28466543109107 0.022716628662387 -184.232088144664 29.3391489759981 -6.27939441240717 6.9576019118442e-10 NMRK1 other 3.86742044797444e-09 9.78099676767058e-06 1 2.28466543109107 -6.27939441240717 4.22711783117499e-17 211.561632934347 63.9787819752378 3.30674680578053 0.00100592449162197 -909.592393542426 133.999442130891 -6.78803119683089 2.97118703813202e-11 TMEM245 other 4.65912927352108e-13 4.28474882769019e-07 1 3.30674680578053 -6.78803119683089 0.836292079972058 24.7244525346734 41.9064943730412 0.589990952585594 0.555441691176956 8.540742559061 93.0787133925711 0.0917582790711702 0.926923871021265 PRUNE2 other 1 1 1 0.589990952585594 0.0917582790711702 8.78310090750347e-11 -90.8857700270731 123.851563054793 -0.733828203579995 0.463374308101592 -1923.44920996876 282.856095976614 -6.80009813233012 2.79795469109203e-11 MEGF9 other 7.59299073453675e-07 4.03604964190026e-07 1 -0.733828203579995 -6.80009813233012 8.23175240113506e-10 214.474128971481 68.4659316503272 3.13256715861042 0.00182593696815178 -638.718151617656 143.472182378685 -4.45186056995914 1.03299940550691e-05 TRIM14 other 6.76732364897313e-06 0.124641248975486 1 3.13256715861042 -4.45186056995914 3.7776807889913e-16 229.68672217465 64.4404187160905 3.56432696669145 0.00039681772912656 -857.948426457197 135.435470083946 -6.33473953260117 4.98022050543245e-10 CORO2A other 4.04589612500968e-12 7.0226089347103e-06 1 3.56432696669145 -6.33473953260117 0.0152373063638561 291.047791025573 135.520801413204 2.14762448266644 0.0321846984162167 -328.266205070964 285.188329611016 -1.15105062510343 0.250217079029623 TGFBR1 ts 1 1 1 2.14762448266644 -1.15105062510343 6.25875348816968e-06 165.16538704303 57.0032120567155 2.89747509102992 0.00391305787779887 -340.00264677472 119.8045725806 -2.83797721114508 0.0047092064577239 SEC61B essential 0.0386790965568886 1 1 2.89747509102992 -2.83797721114508 8.09737000199926e-07 14.8189616981079 10.8956076450203 1.36008584201182 0.174369235096471 -125.788628481992 27.0899328167697 -4.64337174007771 4.30755011180457e-06 C5 other 0.0054543884333467 0.0531034777783267 1 1.36008584201182 -4.64337174007771 0.0823308498530379 -199.712305396913 149.682265084019 -1.33424160360489 0.182684987478559 -696.592920299867 325.728140228307 -2.13857150877912 0.032916756082058 OGN other 1 1 1 -1.33424160360489 -2.13857150877912 0.00641151741485839 -750.718184330991 280.742010233947 -2.67405004226266 0.00771984164313693 -1550.62518804145 612.868959723731 -2.53010886493655 0.0116842670664231 ASPN other 1 1 1 -2.67405004226266 -2.53010886493655 0.0772916452101965 -28.9096942505761 58.2099908969542 -0.496644885269837 0.619640122007008 -286.360196884491 127.11396930557 -2.25278306112925 0.0246704967478407 ECM2 other 1 1 1 -0.496644885269837 -2.25278306112925 0.882350931202366 3.29961736041435 18.9683149589093 0.173954163433192 0.861966798101631 -16.33901438292 41.9875395838456 -0.389139600578223 0.697326567693942 TLE4 other 1 1 1 0.173954163433192 -0.389139600578223 0.0379407739696522 9.12353719264847 9.06051800207457 1.00695536287875 0.31440638172014 -45.1817094413703 22.5461397653791 -2.00396652870703 0.0455716915959302 LHX6 other 1 1 1 1.00695536287875 -2.00396652870703 5.43413299455034e-12 13.7025796590156 35.9330164949358 0.381336748083668 0.703102278489384 -529.405048046118 77.5264295690824 -6.82870410760211 2.29759885374073e-11 PTGR1 other 4.98962091559613e-08 3.31888154422849e-07 1 0.381336748083668 -6.82870410760211 2.38816597295496e-06 39.7731127450086 9.5706663209013 4.15573079359672 3.76452616647348e-05 -31.4628922327333 20.7417112316539 -1.51688989791343 0.129874286720048 SUSD1 other 0.0154156113554243 1 0.323410442961737 4.15573079359672 -1.51688989791343 0.490147189586795 -10.3632956063281 37.5866023397804 -0.275717807974358 0.782869518332741 -105.024312627828 88.1984235534695 -1.19077312718813 0.234261985954351 AMBP other 1 1 1 -0.275717807974358 -1.19077312718813 0.143171259570061 41.7611090797244 28.3594609828394 1.47256356899711 0.141450268493358 -54.2397550908216 66.8246590395637 -0.811672754794138 0.417336401000302 AKNA other 1 1 1 1.47256356899711 -0.811672754794138 0.848018455194658 -0.904582838011608 3.18623905925511 -0.283903003255218 0.776593134321564 -3.96502861024565 7.04690046043177 -0.562662780964371 0.573897181776458 TNFSF8 other 1 1 1 -0.283903003255218 -0.562662780964371 0.000476189799931364 40.6217648016337 21.2929540003059 1.9077561901956 0.0569499428015718 -124.000474081966 47.7471759740082 -2.59702216000099 0.009658511033796 DNM1 other 1 1 1 1.9077561901956 -2.59702216000099 0.000952438057264504 -91.6960446599469 102.483378553793 -0.894740649205043 0.371322900047143 -866.652294719865 232.132684358304 -3.73343502710786 0.000208858512291841 ENG other 1 1 1 -0.894740649205043 -3.73343502710786 5.86872542898188e-08 132.437676891116 35.4065954838062 3.74048041280015 0.000203233675977486 -238.828568830458 80.1986445961128 -2.97796265801273 0.00303153420591475 AK1 other 0.000432466376861675 1 1 3.74048041280015 -2.97796265801273 8.06441233844054e-55 97.5698295830407 10.14815420062 9.61453951666199 2.59733460612883e-20 -251.370943978448 24.7778806831911 -10.1449735428331 2.92933038289167e-22 CDC37L1 other 1.22925837274849e-50 4.54075502652037e-18 3.58302308915472e-16 9.61453951666199 -10.1449735428331 0.0998373831360768 -1.36813413950297 21.3619901716302 -0.0640452564817637 0.948957760974368 -106.62381786007 52.5739458433453 -2.02807333841324 0.0430404430219889 RLN2 other 1 1 1 -0.0640452564817637 -2.02807333841324 3.52192366472026e-30 65.6672466102055 20.090460621053 3.26857844868883 0.0011492895129447 -493.631750060084 49.4445873335265 -9.98353463302891 1.15888264128833e-21 PLGRKT other 4.8257398053997e-26 1.79360266392195e-17 1 3.26857844868883 -9.98353463302891 1.99195489632935e-31 83.6327310994437 21.5417734073413 3.88235125855248 0.000116161916287164 -478.067408768202 47.5917281936807 -10.0451785827706 6.79970321181006e-22 TBC1D13 other 2.76264224571918e-27 1.05286604531667e-17 0.953689332717617 3.88235125855248 -10.0451785827706 2.1303648129548e-20 138.799811472884 19.87154095213 6.98485395809256 8.35606593149554e-12 -200.407230177659 48.9490057511858 -4.09420430715907 4.87962836791877e-05 RIC1 other 2.54195129481766e-16 0.563499483927259 9.93619799914134e-08 6.98485395809256 -4.09420430715907 5.10968218358533e-26 95.8762873223982 10.5232307574906 9.11091750545827 1.58080125053026e-18 -82.7256589537602 25.9242636055889 -3.19105144941999 0.00149980188261022 KDM4C other 6.70032624733544e-22 1 2.13834985159228e-14 9.11091750545827 -3.19105144941999 0.00526252458343047 9.22252415515825 38.1431114078081 0.241787411009956 0.809037541666534 -265.887092131512 92.1525816206563 -2.88529184376005 0.00406825521299191 DOCK8 other 1 1 1 0.241787411009956 -2.88529184376005 1.02923398151135e-14 452.297394690292 58.4191789174226 7.74227579147645 4.91471474905167e-14 54.6600247909438 141.138935831477 0.387278141704349 0.698704318909872 KANK1 other 1.05033327813234e-10 1 6.16600112416022e-10 7.74227579147645 0.387278141704349 5.92161117036447e-06 41.4222483271494 9.68301436549225 4.27782576413059 2.24367707483989e-05 -16.961249403498 22.3465174529071 -0.759010858816905 0.448187343972157 ELAVL2 other 0.0366725379780671 1 0.196546111755974 4.27782576413059 -0.759010858816905 5.25169999988133e-09 187.681602865686 33.7063332537409 5.56814060588616 4.06324542047393e-08 348.563677155905 74.9360004591394 4.65148493408008 4.14947054923546e-06 NCS1 other 4.13203755990663e-05 0.0511920181659179 0.000423674599992817 5.56814060588616 4.65148493408008 4.50404994509276e-21 163.476840688047 23.6030593090047 6.92608693423399 1.2434602941164e-11 -309.430115143478 62.6777298677037 -4.93684305089868 1.06195860467519e-06 TESK1 other 5.45170205354028e-17 0.0134706408245531 1.47163525808676e-07 6.92608693423399 -4.93684305089868 0.110369138495198 83.9125181970007 39.8896170276214 2.10361804523959 0.0358771301290804 70.2673608320157 105.926549937939 0.663359288801388 0.507385665328138 CA9 other 1 1 1 2.10361804523959 0.663359288801388 1.01719091333042e-24 195.984412860898 29.3409115783266 6.67956114239025 5.96270275802126e-11 -391.512382481549 65.2246960455828 -6.00251754654307 3.56270988323293e-09 FUBP3 other 1.30942986273025e-20 4.92900912345276e-05 6.90957995599503e-07 6.67956114239025 -6.00251754654307 0.418028395092616 8.48126058972614 6.42639315184156 1.31975439244574 0.187476252300587 7.9522930193089 15.3972852809668 0.516473707812574 0.605735031330085 TYRP1 other 1 1 1 1.31975439244574 0.516473707812574 2.47549935791893e-18 211.58391511576 39.2843480544079 5.38595969119104 1.08665791901254e-07 -595.850432254229 104.604617117937 -5.69621541258007 2.03665435044617e-08 CREB3 other 2.8183560189907e-14 0.000275498233984854 0.00110686975630617 5.38595969119104 -5.69621541258007 0.000267615120362159 136.483385156879 70.5580372622502 1.93434214517046 0.0536060188429809 -542.186770005862 189.79681532779 -2.85666948135812 0.00445014991439538 RGP1 essential 1 1 1 1.93434214517046 -2.85666948135812 1.0633689121931e-10 90.7611852876905 33.6623871506173 2.696219518883 0.00723405193486051 -390.606978538914 78.6723115404006 -4.96498667562762 9.2530118396308e-07 MPDZ other 9.15879644071913e-07 0.0117735322647462 1 2.696219518883 -4.96498667562762 4.02241508214355e-08 444.239985933388 92.2429467814859 4.81597782197643 1.90693712145949e-06 -316.167490648797 219.663601022404 -1.43932581081811 0.1506397891793 DDX58 other 0.000299589475318051 1 0.0180358112947638 4.81597782197643 -1.43932581081811 0.00212168505895307 385.603309014929 218.484165329086 1.76490277194287 0.0781785673728531 -1177.61456158379 507.433597755577 -2.32072642961065 0.0206951117717298 EDF1 other 1 1 1 1.76490277194287 -2.32072642961065 0.0507852391282618 30.6800853220976 13.6333444305909 2.2503711747542 0.0248270356771919 -6.36286695112981 31.1515542949567 -0.20425519994551 0.838231034001516 PIP5K1B other 1 1 1 2.2503711747542 -0.20425519994551 0.190182633443114 16.2162744040775 11.5312112350197 1.40629410680029 0.16020881030741 -15.0734306520689 28.0826291383404 -0.536752829580674 0.591658203410079 GLIS3 other 1 1 1 1.40629410680029 -0.536752829580674 2.56972169601011e-09 -31.641402218148 133.435762572067 -0.237128350063266 0.812646819299607 -2051.3153558399 338.488764751467 -6.06021696863724 2.54678130757924e-09 BAG1 other 2.0591179950129e-05 3.5354418111815e-05 1 -0.237128350063266 -6.06021696863724 9.65091972979614e-07 169.578031123926 45.0945856566861 3.76049649097469 0.000188021927497979 -234.093118097483 105.192850916441 -2.22537098346572 0.0264670323665711 RAPGEF1 other 0.0064526049313417 1 1 3.76049649097469 -2.22537098346572 2.12364339491969e-06 -61.2105197496874 123.366576489405 -0.496167774866837 0.619990648327277 -1442.98789580421 286.498650284172 -5.0366306939769 6.59380387075276e-07 NPDC1 other 0.0137739510594491 0.00844072833495061 1 -0.496167774866837 -5.0366306939769 0.000292589993244836 73.3291673636542 21.5333710568544 3.405373323575 0.000709878442901956 153.695983504352 48.0475774758284 3.19882898532549 0.00146081381000159 APBA1 other 1 1 1 3.405373323575 3.19882898532549 1.29725532519402e-09 221.334232168588 66.6685742739393 3.31991848601909 0.000960997340161097 -634.192709719036 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-4.06050621858135 5.6174655303624e-05 ZFAND5 other 0.000169995968230103 0.645559138749247 1 2.869485865238 -4.06050621858135 0.0055143324850234 -22.8927521207345 201.429119653576 -0.11365165155915 0.909555564570871 -1179.69131802881 392.316746470252 -3.00698690189169 0.00275952326326183 PDLIM1 other 1 1 1 -0.11365165155915 -3.00698690189169 9.69755813952009e-07 69.4369672979802 13.5095747177428 5.13983369193593 3.83594286889009e-07 88.2041800283275 26.1929470382591 3.36747827189856 0.000812044236772646 CCNJ other 0.00648281761626918 1 0.00379106233732407 5.13983369193593 3.36747827189856 5.40804782683971e-09 -3391.13120809933 602.569090044875 -5.62778818914656 2.93064213752266e-08 -9396.637443918 2619.49656341803 -3.58719212506118 0.000364510290331467 GATA3 other 4.25234800624407e-05 1 0.000307688118018504 -5.62778818914656 -3.58719212506118 0.505249601888795 -33.8742856184449 65.7909271520097 -0.514877766354903 0.606849118352951 -149.937455856706 128.557604805381 -1.16630561127591 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8.89101854623385e-06 1 -1.12206845361447 -6.29530157433449 1.47560832655659e-06 28.6527691774005 16.1552766114985 1.77358579902042 0.0766952082225365 -118.192953562285 30.2800347265552 -3.90332952487109 0.000106879110201874 RAB11FIP2 other 0.00969742604955431 1 1 1.77358579902042 -3.90332952487109 0.00200740926768374 -403.092489058688 157.898626696313 -2.55285620586148 0.0109613583377502 -1393.10870967039 452.560366201781 -3.0782826197583 0.00218892966146921 CXCL12 other 1 1 1 -2.55285620586148 -3.0782826197583 1.95784240416161e-08 131.508397934152 32.3591815327985 4.06402114345379 5.53185448622902e-05 -166.601417914746 64.0266501616383 -2.60206363278655 0.00951803137487999 ERLIN1 other 0.000148913493260532 1 0.468382119349011 4.06402114345379 -2.60206363278655 4.71605833272404e-09 408.76974384533 205.120706725638 1.99282534840369 0.0467824821509624 -1814.37362147956 380.834785007524 -4.76420141464681 2.43899172634588e-06 EIF3A essential 3.72285644785235e-05 0.0304434947282493 1 1.99282534840369 -4.76420141464681 0.676264170681754 1.82018690807297 2.13487412758051 0.852596827399758 0.394256756215446 -0.748141177191258 9.28117958653856 -0.0806084151497687 0.935782910879582 CUBN other 1 1 1 0.852596827399758 -0.0806084151497687 9.61058586589924e-13 33.1368891570429 4.34494827901117 7.62653247614358 1.07511952270847e-13 29.9158966445797 18.6969620599013 1.60004050651305 0.110166973461758 TRDMT1 other 9.08488681903455e-09 1 1.33787873405842e-09 7.62653247614358 1.60004050651305 8.03927309839375e-23 130.931446792514 18.119881976411 7.22584434948111 1.69986742260903e-12 -223.223938785533 44.6746135524847 -4.99666188546399 7.88294140405805e-07 DDX50 other 1.0049895300302e-18 0.0100602098198589 2.0578595018105e-08 7.22584434948111 -4.99666188546399 3.92365546887949e-13 108.726269174475 24.0465909884151 4.52148369915952 7.53349350078485e-06 -291.260263033774 63.262132947608 -4.60402217666275 5.15805287287251e-06 MAPK8 other 3.76513978793676e-09 0.0633512053846202 0.068486989415635 4.52148369915952 -4.60402217666275 1.35923022156465e-12 176.991759878142 59.2901392089851 2.98518037298384 0.00296252952625891 -603.884781768649 113.456292718594 -5.32262043205013 1.50208069148539e-07 SEC23IP other 1.2782201003594e-08 0.00197313319633521 1 2.98518037298384 -5.32262043205013 8.02811745611914e-78 342.996083636558 15.8404897168379 21.6531237207878 2.38949238966563e-75 -90.0191043542505 60.5269737762194 -1.48725599080948 0.13752979215501 ATE1 other 1.24756945268091e-73 1 3.71637751364696e-71 21.6531237207878 -1.48725599080948 1.53298059723323e-131 556.183239915607 16.8970363154497 32.9160232322554 1.49159513210213e-131 144.021421845291 64.083774736567 2.24739292336209 0.0250148636135312 NSMCE4A other 2.39957452884918e-127 1 2.33509217930588e-127 32.9160232322554 2.24739292336209 3.43188791008051e-90 400.455493883823 16.1832996581899 24.7449841714551 4.43168127244155e-91 213.308152010321 59.4525273673187 3.58787357671824 0.000363524200182931 PLEKHA1 other 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-0.235408909859061 0.813980453611191 138.597866286682 125.002329199951 1.10876227006126 0.268025399282665 SPOCK2 other 1 1 1 -0.235408909859061 1.10876227006126 7.98802283531184e-29 288.439790666772 31.0318308129808 9.29496530208315 3.65214896714209e-19 -350.605239938305 81.1203991808806 -4.32203543718434 1.84205155967866e-05 MICU1 other 1.08125877098781e-24 0.218872566321018 4.97495732304096e-15 9.29496530208315 -4.32203543718434 1.97116322517668e-23 203.150381820806 32.8714739969025 6.18014214513012 1.26889851910199e-09 -562.530052935214 87.7096703342177 -6.41354654272093 3.12499459563699e-10 PPP3CB other 2.48662240856038e-19 4.42530484688154e-06 1.40682778812838e-05 6.18014214513012 -6.41354654272093 3.59697806935841e-07 215.69694206515 39.6059440531118 5.44607500772862 7.831736228408e-08 65.4015077050574 93.2275178415395 0.701525785725857 0.483277165870028 CCSER2 other 0.00249702217574861 1 0.000805259119004911 5.44607500772862 0.701525785725857 1.39416294888107e-14 166.119188546298 22.5745999374502 7.35867696466743 6.95631606432011e-13 -54.22546482448 49.1664541624842 -1.10289557683532 0.27056378391764 BMPR1A ts 1.41619072347339e-10 1 8.47974928240622e-09 7.35867696466743 -1.10289557683532 4.92846070966139e-17 117.408475741318 16.9462398261888 6.92829069725984 1.23040926661089e-11 -108.266734487457 35.5598982447385 -3.0446300420299 0.00244454218035516 MINPP1 other 5.42032108848559e-13 1 1.45655848981398e-07 6.92829069725984 -3.0446300420299 0.345326483672984 -647.691994229963 629.091008446913 -1.02956803631476 0.303675461048898 -1697.54237677329 1280.29587170756 -1.32589850071862 0.185435982366703 ACTA2 other 1 1 1 -1.02956803631476 -1.32589850071862 0.00859643022954073 2.47028450313638 110.832897074018 0.0222883689622103 0.982226252545166 -637.807300786128 221.909297865102 -2.87418015793935 0.00421218516827509 LIPA other 1 1 1 0.0222883689622103 -2.87418015793935 2.29094237750999e-05 2.07086864237366 11.2514638241194 0.18405326406813 0.854040004589389 93.1923090202017 21.4900508774152 4.33653273097372 1.72415567664414e-05 TLX1 other 0.134363770440961 0.205186236482422 1 0.18405326406813 4.33653273097372 2.62790207484687e-10 75.7797050234794 16.8663928217514 4.49294083354633 8.57933281516429e-06 -92.9627907071625 32.5339557729943 -2.85740816013307 0.00443403719193482 TWNK other 2.22136562386806e-06 1 0.0777201759725733 4.49294083354633 -2.85740816013307 1.78975580332724e-13 118.504323905656 64.992693986222 1.82334838944786 0.0687972492091319 -776.563005518711 124.134630147425 -6.25581277840398 7.99285812443148e-10 LZTS2 other 1.7435801036014e-09 1.12211735208893e-05 1 1.82334838944786 -6.25581277840398 1.10860338380411e-07 -15.6123574235813 43.2391126296461 -0.361070255009742 0.71818684723667 -445.602912482664 82.6615354209439 -5.39069242076723 1.04678997401275e-07 SFXN3 other 0.00079941390006114 0.00138437974063187 1 -0.361070255009742 -5.39069242076723 0.0011056756525565 8.25521096318529 43.8748665253455 0.18815352881852 0.850826207164604 -277.499415736454 83.8000395866954 -3.31144731082575 0.000989506573415869 KAZALD1 other 1 1 1 0.18815352881852 -3.31144731082575 2.25077450556702e-22 50.1945477906373 47.4674685249896 1.05745154208533 0.290773181032886 -906.034315341079 96.7196854544618 -9.36763091281623 1.93727716589316e-19 FBXW4 other 2.79231085160645e-18 2.97759500397779e-15 1 1.05745154208533 -9.36763091281623 0.0121088915297412 78.5180436021651 27.4594489006419 2.85941804171932 0.0044070574274314 11.7067638967092 55.9378087365091 0.209281774905647 0.834306624016986 NPM3 other 1 1 1 2.85941804171932 0.209281774905647 1.54697286669861e-06 134.29468060597 69.6059371838144 1.92935669052665 0.0542073081716003 -500.800678875505 132.836638949992 -3.77004930894133 0.000181112260994749 TNKS2 other 0.0101481420055429 1 1 1.92935669052665 -3.77004930894133 3.78095152449176e-17 240.105749466062 63.973142702466 3.75322735953078 0.000193381851360116 -826.84701509083 130.345351670196 -6.34350979529323 4.73547031982055e-10 GBF1 essential 4.17303619758156e-13 6.68127507423482e-06 1 3.75322735953078 -6.34350979529323 5.23783330225698e-13 501.475220690245 64.969628112443 7.71860999146157 5.74539170766119e-14 366.720118064609 251.712399148026 1.45690128617363 0.145725931041773 ARHGAP21 other 4.99794053701361e-09 1 7.19610311384564e-10 7.71860999146157 1.45690128617363 6.99456753903504e-14 -7.89049893432972 10.5570076381586 -0.747418132559577 0.455134739414458 -154.710211126212 20.2049024350311 -7.65706301347819 8.76859921970233e-14 CPEB3 other 6.92532132039859e-10 1.30345227400875e-09 1 -0.747418132559577 -7.65706301347819 9.38695862149991e-06 17.3321460864916 17.7355517275829 0.977254407007598 0.328879194529533 -151.527646113738 36.6050222983763 -4.13953158882406 4.03489293004564e-05 FBXL15 other 0.0572510606325279 0.468007230955994 1 0.977254407007598 -4.13953158882406 1.70113694462447e-17 178.583516887245 34.4334744378209 5.18633451322859 3.03421676512241e-07 -373.463020946859 71.0684459647641 -5.25497660567987 2.13199435104673e-07 CUEDC2 other 1.89302519197811e-13 0.00277948103545963 0.00301722515123772 5.18633451322859 -5.25497660567987 2.78009387636633e-17 94.1538273296386 16.7583471787536 5.61832418945274 3.08381626011342e-08 -166.605637104195 35.0431803612394 -4.75429556868858 2.55431478955292e-06 SUFU ts 3.07950998685098e-13 0.0318523054257249 0.000323399811198094 5.61832418945274 -4.75429556868858 9.18190869633716e-05 51.8937807112101 17.1238578106007 3.03049588972205 0.00255721645875472 -144.396739195964 62.339175305172 -2.31630813993114 0.02091080671128 ANKRD26 other 0.501332214820009 1 1 3.03049588972205 -2.31630813993114 5.03660280701202e-11 172.766081933936 31.9556804761263 5.40642788261095 9.61816564284645e-08 -354.071380062007 115.677974356177 -3.06083662021785 0.00231553252704151 ACBD5 other 4.40904209725832e-07 1 0.00098345743698105 5.40642788261095 -3.06083662021785 3.76519578954193e-09 75.5628876476868 21.0558795523843 3.58868350570188 0.000362594973317696 -144.613539044818 40.8450227048674 -3.54054250599266 0.000433792166876824 LHPP other 2.98994197647524e-05 1 1 3.58868350570188 -3.54054250599266 1.14241198224332e-40 532.411923275001 37.3303465589708 14.262174674268 2.641378075198e-39 -246.785938825408 148.169851672887 -1.66556108438465 0.0963906758503681 LARP4B other 1.67786047832077e-36 1 3.98689606670386e-35 14.262174674268 -1.66556108438465 1.05091845754085e-50 771.65108314741 45.5465122236122 16.9420455151201 8.65103691290471e-52 316.290354772714 180.781069088902 1.74957674698324 0.080769043653651 GTPBP4 essential 1.59214146317439e-46 1 1.32819369723826e-47 16.9420455151201 1.74957674698324 1.11197547156195e-08 77.4315355930424 17.2590652988337 4.4864269444693 8.86161558534853e-06 -72.7609115805433 33.1571853569743 -2.19442364595156 0.0286317144021623 EDRF1 other 8.57444286121421e-05 1 0.0802153442785749 4.4864269444693 -2.19442364595156 3.41054188059789e-25 324.72350661891 41.7735784206526 7.77341848354483 3.91918404084054e-14 -360.741806186698 80.2686689957288 -4.49417949369378 8.55930950123162e-06 BCCIP other 4.41699278956233e-21 0.103798746321436 4.92876584976107e-10 7.77341848354483 -4.49417949369378 0.00224296074656625 61.3770424578086 50.497694065251 1.21544247898725 0.224721699698132 -282.330589215062 105.527829044414 -2.67541360200101 0.00768726656626666 NEURL1 other 1 1 1 1.21544247898725 -2.67541360200101 0.199246194660577 -67.3919649922121 111.010003759351 -0.607080107287495 0.54405011497021 -417.142497424503 231.894978316441 -1.79884230548225 0.0725957543530465 SH3PXD2A other 1 1 1 -0.607080107287495 -1.79884230548225 1.03606934465597e-33 587.941480901993 44.6458399903904 13.1690092745157 1.5510697771483e-34 116.385472140519 191.719595281789 0.607060910855025 0.544066120889516 PITRM1 other 1.46438041173674e-29 1 2.31481653541613e-30 13.1690092745157 0.607060910855025 8.68391211041986e-29 60.381677741569 11.1857044111443 5.39811133230113 1.00581746424005e-07 -191.772077637238 23.3158313702247 -8.22497274886535 1.43545439752891e-15 STN1 other 1.17502014766091e-24 2.16509586779285e-11 0.00102683904924267 5.39811133230113 -8.22497274886535 0.0420331762575504 -15.1513348422795 15.0564266197705 -1.0063035024781 0.314717807106037 -135.91680012253 54.7426387460162 -2.48283245448086 0.0133351769840701 MAP3K8 other 1 1 1 -1.0063035024781 -2.48283245448086 0.524463294383227 29.9044546714831 28.5347662600583 1.04800068796575 0.295112385242894 -7.34842640387337 74.9826454564564 -0.0980016957142532 0.92196772040952 DKK1 other 1 1 1 1.04800068796575 -0.0980016957142532 0.507870870663354 7.32540424356402 12.056413306433 0.607593988143666 0.54371411435961 -16.0726622396727 23.8926475481705 -0.672703274397208 0.501425984505256 EBF3 other 1 1 1 0.607593988143666 -0.672703274397208 7.09547540452418e-14 214.160565215792 28.0672988448146 7.6302520737708 1.07795731879909e-13 41.7672179047376 55.6595676351179 0.750405000961326 0.453340096205693 GLRX3 essential 7.02168246031713e-10 1 1.34119449604983e-09 7.6302520737708 0.750405000961326 1.84606411478613e-05 -98.7516269824516 48.8016716012887 -2.02352959933946 0.0435069827554137 -441.143880048803 93.5592889708159 -4.71512647115573 3.07340925237729e-06 SORCS1 other 0.109600826494852 0.0381502290497593 1 -2.02352959933946 -4.71512647115573 3.02280840596838e-09 759.524529846342 119.083487118509 6.37808438621287 3.83533048396203e-10 521.053148942324 516.500709612861 1.00881400401729 0.313512338288668 FAM208B other 2.41159654628157e-05 1 4.33929290955464e-06 6.37808438621287 1.00881400401729 0.000139451945593369 144.69973532032 34.1011423338223 4.24325185073943 2.58979400626638e-05 98.4163457222697 63.6754722434287 1.54559271026728 0.122784474010775 XPNPEP1 other 0.743697225849436 1 0.225571057945801 4.24325185073943 1.54559271026728 3.63658172666402e-07 354.179815259787 71.0515432836719 4.98482930688403 8.35839644134207e-07 -12.8418429912138 131.994605531678 -0.0972906653229242 0.922531534399522 SMC3 essential 0.00252378771830483 1 0.00808340519842191 4.98482930688403 -0.0972906653229242 4.09284798892734e-12 212.363491025762 77.8090633013242 2.72928990551346 0.00655295219336998 -744.887023290586 144.519044910642 -5.15424817366568 3.57143148205013e-07 SHOC2 other 3.77565226978547e-08 0.00462071805147646 1 2.72928990551346 -5.15424817366568 2.67068610770393e-15 210.437169746723 30.8844094907311 6.8137022276524 2.58760065895717e-11 -229.648283128452 83.6469188167388 -2.74544820511066 0.00624763551825296 TFAM essential 2.78338906144904e-11 1 3.03370301256138e-07 6.8137022276524 -2.74544820511066 3.30489746027161e-10 436.497391870467 97.4523789523756 4.47908400557138 9.20153652637216e-06 -850.177342222062 246.654764331024 -3.44683121985464 0.000612592451359479 CCDC6 other 2.77776631535829e-06 1 0.0831910917349307 4.47908400557138 -3.44683121985464 1.41490509150805e-11 168.410425328215 23.9938715599112 7.01889334148114 6.91282635400799e-12 -6.7071513554294 87.6494834861769 -0.0765224287543825 0.939032512197343 CUL2 essential 1.2729901108298e-07 1 8.23594131816513e-08 7.01889334148114 -0.0765224287543825 4.36062652174896e-16 372.394435073591 44.3769428623987 8.3916198605273 4.45029959803227e-16 -54.3261283565034 163.18215135028 -0.332917098512135 0.739329509834389 CCNY other 4.66107368909746e-12 1 5.79874037623605e-12 8.3916198605273 -0.332917098512135 8.80113729349064e-15 128.654651598169 16.0089169937655 8.03643692126533 5.97113222868057e-15 223.404534260085 70.0015346929356 3.19142337721676 0.00149900319172778 UBE2S other 9.00972424734637e-11 1 7.6287185353623e-11 8.03643692126533 3.19142337721676 2.16578200918977e-27 953.499294607322 91.8720056161324 10.3785618721694 3.98860068343123e-23 -1083.77274341122 332.000230189129 -3.26437346984316 0.00116680176201753 ZMIZ1 other 2.88682894781688e-23 1 5.63868478616673e-19 10.3785618721694 -3.26437346984316 2.02487980230015e-05 -298.089869066641 115.288248702144 -2.58560497207984 0.00998264334390643 -1253.36973847135 276.141886820753 -4.53886135457938 6.98297355122275e-06 DNAJC12 other 0.119670396315939 0.0851433965100589 1 -2.58560497207984 -4.53886135457938 1.61606640854874e-17 660.551278833571 75.7484043719607 8.72033258403636 3.44560866932194e-17 -243.168805685079 283.799424383246 -0.856833329431638 0.391917785344822 PPIF other 1.79965155255988e-13 1 4.57783567806113e-13 8.72033258403636 -0.856833329431638 7.75192789325314e-12 31.2111272617252 8.22935011927805 3.79266002896269 0.00016577338576695 -104.024397658818 21.500389388358 -4.83825645107362 1.7090245737523e-06 PBLD other 7.06665746748956e-08 0.0214653486463289 1 3.79266002896269 -4.83825645107362 3.77635980760034e-57 853.161863712338 47.4382432836567 17.9846850274548 4.4455275833562e-57 56.4384211656605 173.763452302895 0.324800298438363 0.745457312732914 TSPAN14 other 5.78122922945536e-53 1 6.85722629732694e-53 17.9846850274548 0.324800298438363 0.550031917705853 4.56180920127376 5.40656461291661 0.843753756382624 0.399177884340143 -3.38864200867264 10.4398218705704 -0.324588106069621 0.745617605865565 LGI1 other 1 1 1 0.843753756382624 -0.324588106069621 8.10913127607254e-10 12.6049908384236 22.5901708835611 0.55798563469904 0.577083746680962 -255.600865665657 43.9557627459631 -5.81495689525103 1.03495677043554e-08 TBC1D12 other 6.67138230082488e-06 0.00014143719224772 1 0.55798563469904 -5.81495689525103 1.89892135506161e-06 149.776433797479 71.8350270213142 2.08500560253202 0.0375344623204295 1684.95317018877 327.52938055842 5.14443366062615 3.75184862302296e-07 KRT23 other 0.0123752704709365 0.00484963953011948 1 2.08500560253202 5.14443366062615 1.24089174889168e-43 743.480901848333 54.7241370861965 13.5859776222194 4.91976844692142e-36 -667.858932710265 216.705536457852 -3.08187295823962 0.00216979863116483 NUFIP2 other 1.84433740637771e-39 1 7.36981313348829e-32 13.5859776222194 -3.08187295823962 1.91887320486379e-70 715.564481325721 34.351295612829 20.8307858134609 1.05503494204684e-69 362.529477500188 130.130994523458 2.78588109487502 0.00554265164436598 GIT1 other 2.97041572112914e-66 1 1.63699221607988e-65 20.8307858134609 2.78588109487502 6.82437703429791e-96 6590.32575360923 253.845463011711 25.9619599870697 3.73563712720594e-95 -1884.00766334976 2004.89238670613 -0.939705131229027 0.347816307249359 RPL19 essential 1.0652852550539e-91 1 5.83394450155752e-91 25.9619599870697 -0.939705131229027 2.35047087299223e-108 177.757605490231 6.41511177433016 27.7091984899658 1.19986064878769e-103 -314.943137131469 68.6217567260656 -4.58955223761911 5.60442779344215e-06 FBXL20 other 3.67496120992335e-104 0.0686822626086336 1.87562216618491e-99 27.7091984899658 -4.58955223761911 0.016951617772058 49.7799660264474 24.8852089195962 2.00038368925436 0.045960929032598 -64.8842858797391 58.2950405584193 -1.11303269125813 0.266191444063634 RUNDC3A other 1 1 1 2.00038368925436 -1.11303269125813 3.46735368913579e-34 421.537684253484 52.3974069487966 8.04501040796572 5.55568281902806e-15 -824.465991351665 122.774540071016 -6.71528470703104 4.7895921978013e-11 UBTF essential 4.91844120803912e-30 6.88264398824046e-07 7.09960707443595e-11 8.04501040796572 -6.71528470703104 2.61299812264882e-155 1415.97110717133 36.606382890196 38.6809893623923 9.78642574084582e-155 -120.776964957751 728.524578434427 -0.165782965369948 0.868392560345524 PSMD3 essential 4.09300025931711e-151 1 1.5330435923035e-150 38.6809893623923 -0.165782965369948 9.39949586862566e-15 117.531949605493 15.7537469217747 7.46057113835196 3.66989701352526e-13 -350.919594427218 155.269193431746 -2.26007224402487 0.0242320154684907 RAPGEFL1 other 9.61004457608287e-11 1 4.50810149141443e-09 7.46057113835196 -2.26007224402487 0.0019204226800722 20.4226499628965 5.75746445971255 3.547160404689 0.000424622058864841 9.24454391986229 24.0338353484887 0.384647052200248 0.70065618840817 RGS9 other 1 1 1 3.547160404689 0.384647052200248 6.5579089287336e-32 424.116915771804 35.816773326746 11.8412932371855 7.67481722417505e-29 -397.343020236113 160.958922198512 -2.46859891212534 0.0138811277815056 RNF43 other 9.13254397415441e-28 1 1.12221177451888e-24 11.8412932371855 -2.46859891212534 0.255503288209631 -4.52162784111155 6.40667491330327 -0.705768265488627 0.480632169983324 -19.7434067055097 11.9388849864213 -1.6537060812601 0.0987599213627093 ASPA other 1 1 1 -0.705768265488627 -1.6537060812601 7.27401423458834e-29 109.005473994029 9.33424479279345 11.6780174951258 3.87727652276966e-28 -30.4384575540192 37.5749273868083 -0.810073622782446 0.418269125493596 RAD51C essential 9.851197477903e-25 1 5.65190598724134e-24 11.6780174951258 -0.810073622782446 0.00859567479442222 11.5355888634771 14.0443721045818 0.821367361785706 0.411809165669975 195.741576145461 63.2974332469669 3.09240937751359 0.00209074227855909 SEPT4 other 1 1 1 0.821367361785706 3.09240937751359 5.96355837979551e-55 445.591724366008 25.419622083697 17.5294393795017 1.61261166621867e-54 18.4312877516802 114.565237949016 0.160880281677437 0.87224946172343 MTMR4 other 9.09263746167421e-51 1 2.48229313781039e-50 17.5294393795017 0.160880281677437 8.31992637716086e-43 352.161703441726 23.393817903472 15.0536224952601 1.29720203918623e-42 -3.53082393498401 91.0174284556266 -0.0387928333605401 0.969070798752998 TRIM37 other 1.23301308909524e-38 1 1.96941213589253e-38 15.0536224952601 -0.0387928333605401 0.295156158086834 -5.0494690312978 4.70997616166312 -1.07207953033775 0.284156210846549 5.15148982869763 8.67777296297083 0.593641922954161 0.5529965825441 P2RX1 other 1 1 1 -1.07207953033775 0.593641922954161 5.28085601898189e-35 364.544573797942 30.4150852874401 11.9856502243142 2.7207996005894e-29 -455.472941314475 116.850041178487 -3.89792709288604 0.000110161733673463 DHX40 other 7.53366919667957e-31 1 3.98542725494335e-25 11.9856502243142 -3.89792709288604 2.18868059875211e-34 56.7041321587618 4.2064550901742 13.4802656733971 1.50790279639763e-35 45.60960868353 16.2625315228348 2.80458233821026 0.00523427826603295 TUBD1 other 3.10836418634775e-30 1 2.25642574452941e-31 13.4802656733971 2.80458233821026 8.45264653538988e-32 1354.77300437044 113.384924402468 11.9484403372848 2.68112047432477e-29 -155.224727524941 311.019415566021 -0.499083721967805 0.617927883801044 KPNB1 essential 1.17601671246879e-27 1 3.92784149488579e-25 11.9484403372848 -0.499083721967805 1.28022397712066e-33 114.373546066525 10.8158684041084 10.5746059209707 7.44854824135774e-24 -86.4643594904175 26.1757715450001 -3.30322104705767 0.00101996123994336 GOSR2 essential 1.80742021089894e-29 1 1.0593325308859e-19 10.5746059209707 -3.30322104705767 8.077626903586e-60 303.363912180385 20.6763027809849 14.6720579299785 3.68112235621157e-41 -493.669150582434 66.6915775749182 -7.40227129921869 5.27864529416203e-13 PNPO other 1.24072349239081e-55 7.77808384094776e-09 5.57469169624681e-37 14.6720579299785 -7.40227129921869 4.05671217135147e-51 296.236813862456 18.4444541682736 16.0610236095799 4.13103968804077e-47 -202.373665824522 73.4271335610756 -2.75611556668205 0.00606286254684286 RPS6KB1 other 6.14835296690028e-47 1 6.30851070760706e-43 16.0610236095799 -2.75611556668205 1.35865925758229e-18 121.645383688301 14.5511786363361 8.35983027412893 5.4377502128973e-16 -18.1507212983171 37.6354083147593 -0.482277783371331 0.629805507348305 TRIM16L other 1.55525725215444e-14 1 7.07668812706455e-12 8.35983027412893 -0.482277783371331 3.27317527337913e-51 721.229674256939 51.2348706745525 14.0769297308905 1.87525523278062e-38 -919.958044056268 165.563581185733 -5.55652419129686 4.36675811993259e-08 CDK5RAP3 other 4.96213371444276e-47 0.00058497091774617 2.82563458475384e-34 14.0769297308905 -5.55652419129686 6.43757599146554e-39 558.108510479115 39.9271676942815 13.9781643103888 5.0586307781307e-38 -9.64078046139776 149.918634627479 -0.0643067520282145 0.94875022391333 CBX1 other 9.38405452275932e-35 1 7.61020414261983e-34 13.9781643103888 -0.0643067520282145 7.25770067265595e-40 141.823805104425 11.4757174051697 12.3586003468972 4.85286322756966e-31 -217.013486692284 40.8713042412499 -5.30967853169854 1.6125825729808e-07 RECQL5 other 1.06259995548356e-35 0.00211474078620702 7.16137026492455e-27 12.3586003468972 -5.30967853169854 3.55079560259477e-29 44.2575033102906 7.51458555331555 5.88954680152168 6.82742500971722e-09 -92.3841885231221 13.6314506014431 -6.77728227349052 3.22539462955183e-11 PIGL other 4.82340074656474e-25 4.64779366118419e-07 7.36064690297613e-05 5.88954680152168 -6.77728227349052 4.61329225392324e-20 104.887832258644 11.0029854331622 9.53267028260529 5.20512220836893e-20 -19.1712382586083 40.2030302094586 -0.476860529137376 0.633654711249442 GALK1 other 5.47044195470218e-16 1 7.15912508539063e-16 9.53267028260529 -0.476860529137376 4.13147119634217e-54 170.504647869815 10.0538641024153 16.9591160307065 1.7438662894564e-51 -89.3465540201244 38.6401303326342 -2.3122736194465 0.0211599470936857 INTS2 essential 6.29223063202913e-50 1 2.67666036768663e-47 16.9591160307065 -2.3122736194465 2.09304570309505e-50 101.963220145536 34.6466059905623 2.94294974155075 0.00339023481105774 -893.070475160276 64.4769226436262 -13.8510096100028 1.43876316593925e-37 CAMTA2 other 3.16824328077498e-46 2.25511738629317e-33 1 2.94294974155075 -13.8510096100028 3.12263383665973e-35 725.343689721768 55.6460813023313 13.0349464462896 9.48710315668448e-34 -376.225893583852 217.847718863955 -1.72701323450077 0.0847672336401554 MED13 other 4.46286827935409e-31 1 1.41253478899875e-29 13.0349464462896 -1.72701323450077 0.0192467274948567 28.5102727131822 17.5965007189946 1.6202239961498 0.105783486490303 -128.278430913176 68.8828437571833 -1.86226967291545 0.0631224463976301 HOXB6 other 1 1 1 1.6202239961498 -1.86226967291545 0.351929555953872 571.299349928935 394.943234910947 1.44653534844762 0.148603025966294 453.540252934643 736.006168456825 0.616218005190874 0.538008405187099 ENO3 other 1 1 1 1.44653534844762 0.616218005190874 8.34843768756321e-18 2376.52000204712 285.781544829294 8.31586239575647 7.31638820976504e-16 -57.6613338562204 532.328532022062 -0.108319074382867 0.913782458773418 PFN1 essential 9.38113942951478e-14 1 9.49886681273796e-12 8.31586239575647 -0.108319074382867 5.69173605938161e-63 476.895300850715 52.7618366471033 9.03864101699912 2.7584452619635e-18 -1164.4758374049 98.6819476517363 -11.8002924051977 8.88690414152667e-29 RNF167 other 8.77267278832488e-59 1.38946746252769e-24 3.72086681386257e-14 9.03864101699912 -11.8002924051977 1.32111193581146e-43 371.19404579397 33.7351683204311 11.0031775228809 1.44270375551879e-25 -327.335496546525 63.0958345230779 -5.18790977282025 3.00430449954194e-07 SLC25A11 other 1.9633044478094e-39 0.0038965829359059 2.07273248555385e-21 11.0031775228809 -5.18790977282025 5.4875949016697e-05 150.190701089384 69.218003652292 2.1698213349788 0.0304631003561597 -287.559651298358 121.578631829428 -2.36521539164709 0.0183780633410869 RASD1 other 0.30851258537187 1 1 2.1698213349788 -2.36521539164709 1.24689574350515e-15 25.9667504109574 6.68062977308229 3.88687164129094 0.000114054418703879 -65.9696595260324 12.494969838851 -5.27969738037391 1.87204669012699e-07 CHRNE other 1.31422811365442e-11 0.00244639061465795 0.936957049652365 3.88687164129094 -5.27969738037391 8.96911561482971e-31 235.588374844281 47.3590163227524 4.9745200204063 8.88234874871824e-07 -641.660481827988 83.2843138999036 -7.70445779981062 6.62127224888082e-14 RAI1 other 1.2353162936305e-26 9.84980459743511e-10 0.00857324301226284 4.9745200204063 -7.70445779981062 1.0131804149583e-60 334.903536872604 32.2922863409933 10.3710072844072 4.00029492564537e-23 -596.160161595896 59.1048078590801 -10.0864918301957 4.70583589410175e-22 NUP88 essential 1.55857543233035e-56 7.29075155073184e-18 5.6548169068923e-19 10.3710072844072 -10.0864918301957 5.17047724954252e-51 728.686972831603 58.5184458316961 12.4522612054217 1.66208395995852e-31 -570.382937353879 106.205522592671 -5.37055817277472 1.16326654201726e-07 C1QBP essential 7.83379008078188e-47 0.00153597714207959 2.45656009281869e-27 12.4522612054217 -5.37055817277472 0.0640043639110224 -28.0196270342345 73.170668920637 -0.382935231392041 0.701924271490928 -458.16615046746 200.346251336821 -2.28687159061037 0.0226042931015609 SLC6A4 other 1 1 1 -0.382935231392041 -2.28687159061037 1.8805330533042e-14 250.792785430793 40.9033662812492 6.13134830288432 1.72713370043809e-09 -273.194219595327 106.817004995616 -2.55759108399023 0.0108230602468012 BLMH other 1.90140697019587e-10 1 1.90312862451273e-05 6.13134830288432 -2.55759108399023 1.06800997165402e-20 1055.2806934436 160.401220983194 6.57900661213896 1.16848553936468e-10 -1801.45687207322 415.980140458954 -4.33063191450837 1.78825900389557e-05 CPD other 1.28203916997349e-16 0.212606112973145 1.34364152171545e-06 6.57900661213896 -4.33063191450837 2.66500485085119e-54 400.023657888312 30.0472357322111 13.3131600342017 5.68553616256595e-35 -421.479201923215 77.6750896760997 -5.42618236658312 8.86857163293037e-08 GOSR1 other 4.05906888833145e-50 0.0011760612842429 8.49419102687353e-31 13.3131600342017 -5.42618236658312 1.23019717363931e-36 740.765606829706 57.1883544513447 12.9530848358286 1.7067943744969e-33 -736.236378480731 270.991220895973 -2.71682741620385 0.00680861579316465 CCDC47 other 1.77123789060588e-32 1 2.53971002925139e-29 12.9530848358286 -2.71682741620385 8.3223676634666e-47 33.9948630028642 5.00328970418778 6.79450222009138 2.85079204774848e-11 -94.3588748990113 9.02934960569674 -10.4502404956697 1.99751413509685e-23 MED31 other 1.24827192584336e-42 3.10213945180541e-19 3.33685209188959e-07 6.79450222009138 -10.4502404956697 2.884107957539e-57 221.619919613377 18.253747491024 12.1410641690072 4.60448183321047e-30 -235.989891860858 35.1679022939985 -6.71037726071965 5.05022140606376e-11 DRG2 other 4.41556928299221e-53 7.25413802766998e-07 6.77089053573599e-26 12.1410641690072 -6.71037726071965 8.21319190095835e-87 601.929923760318 25.3051987040347 23.7868088213963 2.06951722365705e-85 -73.9821816154245 112.456402156332 -0.65787434238362 0.510907227331949 FTSJ3 essential 1.27961529816931e-82 1 3.22596344823661e-81 23.7868088213963 -0.65787434238362 2.31119270261628e-52 167.009606807097 15.6614038474607 10.6637698914951 3.44755360950709e-24 -322.640514493275 40.9533286291497 -7.87824885774062 1.88878892307767e-14 AKAP10 other 3.51023947673361e-48 2.82260616664727e-10 4.91310864890855e-20 10.6637698914951 -7.87824885774062 0.213692062661394 110.776464615197 66.0158062475466 1.67802941313489 0.0939308751531197 39.4277913432831 163.738675048561 0.240797058676514 0.809805527923678 ALDH3A1 other 1 1 1 1.67802941313489 0.240797058676514 3.93208488449031e-74 1143.1109763592 53.2810571282699 21.4543599164567 8.65532685558372e-74 57.9103768684943 236.781226569695 0.244573346069092 0.806882361268036 SMARCD2 other 6.09827044735602e-70 1 1.34573021950616e-69 21.4543599164567 0.244573346069092 0.148012081468917 -6.35238857904586 8.08405001998479 -0.785792834450796 0.432347457904571 57.1614247833709 35.4476553620053 1.61255869251763 0.107448289995735 ICAM2 other 1 1 1 -0.785792834450796 1.61255869251763 1.7541064253445e-22 1226.43618745126 145.55346076072 8.4260187359436 3.28051307609354e-16 -1940.40428691585 429.514776156987 -4.51766596780976 7.69111614103328e-06 SYNGR2 other 2.18035428670322e-18 0.0935162811588237 4.28500617999338e-12 8.4260187359436 -4.51766596780976 1.10310823881846e-48 68.3237013967603 6.91672578948431 9.87804106686356 3.07628268927942e-21 -153.625918822688 18.9505332008289 -8.1066805453246 3.61172779479974e-15 B9D1 other 1.66260473754719e-44 5.43167743059933e-11 4.27664819463625e-17 9.87804106686356 -8.1066805453246 1.58581753590324e-41 295.301493384567 20.3270024244849 14.5275475064076 2.3390792739921e-40 117.429192432533 48.4181299736195 2.42531449472572 0.0156358868733456 UTP6 other 2.33765362967497e-37 1 3.53715567813086e-36 14.5275475064076 2.42531449472572 4.87409635977038e-56 125.490822294259 10.124157122224 12.395187152794 4.78022000407664e-31 -161.99292158832 23.2355832613279 -6.97176050053938 9.67230082125674e-12 C17orf75 other 7.44761923772914e-52 1.40451480225469e-07 7.0546486820163e-27 12.395187152794 -6.97176050053938 2.5616945887137e-10 157.121543364431 23.1596321623771 6.7842849257198 3.07402473921476e-11 81.6913348686603 68.9629321349288 1.18456875802247 0.236709093151256 CYTH1 other 2.16744979151066e-06 1 3.59445712756382e-07 6.7842849257198 1.18456875802247 4.99654651780512e-38 963.477115703863 68.5569788937031 14.0536693893371 3.55657681487801e-38 552.280614448122 157.619584444972 3.50388320330164 0.000498707059250924 PSMD11 essential 7.25398623454948e-34 1 5.35371507943586e-34 14.0536693893371 3.50388320330164 9.66481785179093e-11 3079.07656859243 475.745661933778 6.47210645300854 2.1685143131849e-10 -1707.36492977375 1350.75419683052 -1.26400860628825 0.206771278471067 LGALS3BP other 8.33590539716968e-07 1 2.47123891130551e-06 6.47210645300854 -1.26400860628825 0.0124668364570369 7.60044948043915 6.7267215413182 1.12988911964828 0.259047898325643 -32.3646578112075 15.8410329171277 -2.04309011795652 0.0415510105978532 ASIC2 other 1 1 1 1.12988911964828 -2.04309011795652 4.05780823250442e-06 7.41910495236418 2.46461953656568 3.0102435050492 0.0027361616440141 28.1561745234116 5.71112895570153 4.93005406493278 1.10495699204171e-06 CCL7 other 0.0255723074812429 0.0140042249171367 1 3.0102435050492 4.93005406493278 0.110079673390006 12.0257760518864 37.7577876485093 0.318497899395893 0.750234192171388 177.208610883561 87.4940700352939 2.02537852922007 0.0433348928958405 CCL2 other 1 1 1 0.318497899395893 2.02537852922007 1.94340089757554e-05 34.0398643111023 10.4231948499258 3.26578029109229 0.0011628873187166 107.023756004865 24.1102233395346 4.43893673226052 1.10251237125879e-05 CCL8 other 0.115146503181351 0.132786589994409 1 3.26578029109229 4.43893673226052 8.4918010310265e-49 49.1132957154057 6.20877725651765 7.91030080260153 1.44298220824151e-14 -194.156759436812 18.1331925606661 -10.7072573562126 2.08712385036144e-24 PEX12 other 1.28005408741693e-44 3.24714728639233e-20 1.83056722937519e-10 7.91030080260153 -10.7072573562126 0.0451051502766258 -0.775963267421748 2.96250584971155 -0.261928011888078 0.793475726496244 -21.7003926613793 8.84267366468383 -2.45405331964778 0.0144368041047372 KRT32 other 1 1 1 -0.261928011888078 -2.45405331964778 2.77294564809628e-20 152.847513466423 24.9861969820062 6.11727801459725 1.83298665741826e-09 -259.806731327503 56.4484398921628 -4.60254936759685 5.21185237697397e-06 DHX58 other 3.30257826688267e-16 0.0639963353368633 2.01830160848324e-05 6.11727801459725 -4.60254936759685 5.01092711640664e-32 412.432618805138 43.4382219829284 9.49469384283793 7.15743154055273e-20 -395.1682859022 98.1349768590867 -4.02678329939005 6.4673681809493e-05 KAT2A other 6.98723677111741e-28 0.739672898855171 9.82858499148701e-16 9.49469384283793 -4.02678329939005 1.59508132229438e-49 603.474637725615 74.0376917063157 8.15091102677013 2.54955916625589e-15 -1667.26811420782 167.264837984275 -9.96783385139538 1.37096412036291e-21 RAB5C other 2.40857279666451e-45 2.12129278343753e-17 3.27745830822194e-11 8.15091102677013 -9.96783385139538 3.52094279028462e-18 134.594559328505 32.0520477587755 4.19924993065863 3.13484011750976e-05 -429.683018863018 71.3954473188204 -6.01835320036927 3.2652276710487e-09 NAGLU other 3.99169284134568e-14 4.52070771056692e-05 0.271536489192019 4.19924993065863 -6.01835320036927 2.11373451579412e-07 61.453423575121 39.197725654382 1.5677803379965 0.117522546145707 -380.428980285626 87.1656112167773 -4.3644388535235 1.52961056294005e-05 HSD17B1 other 0.00149356480886012 0.182635501215042 1 1.5677803379965 -4.3644388535235 4.3135272623546e-46 343.070334203009 23.9684685244005 14.3134023708588 1.37706538494513e-39 -52.0221310540793 53.2996793559094 -0.976030844514106 0.329489469128473 MLX other 6.45907572264978e-42 1 2.07978185088263e-35 14.3134023708588 -0.976030844514106 9.90068882417874e-07 -0.33201167220112 8.45569017886727 -0.0392648814204303 0.968693798522489 -92.9567679265481 18.8882159094851 -4.92141599672567 1.14467154757709e-06 CNTNAP1 other 0.00660771972125689 0.0144949758069687 1 -0.0392648814204303 -4.92141599672567 0.82566560290086 -1.7487257867926 3.42461002171713 -0.510635014119295 0.609823355932362 -7.45847821312996 16.8644952058523 -0.442259203260453 0.658485532004288 ABI3 other 1 1 1 -0.510635014119295 -0.442259203260453 9.72706811494143e-37 99.945461272517 23.3357532087575 4.28293273323653 2.18546944662584e-05 -547.995438561026 52.0961605990669 -10.5189217834767 1.17554754119372e-23 EZH1 other 1.40167051536306e-32 1.82644821475269e-19 0.191665670469087 4.28293273323653 -10.5189217834767 0.00583498018221106 7.05641425627464 2.29332336950139 3.07693818940537 0.00220157981276895 16.2171864398348 10.3942057202192 1.56021411124166 0.119317657475137 DLX4 other 1 1 1 3.07693818940537 1.56021411124166 6.62394150343581e-58 346.563148637932 21.0223711100705 16.4854452822363 1.70707201936453e-49 -472.01634063212 100.890839515526 -4.67848560779874 3.68318682070606e-06 PPP1R9B other 1.01518527481657e-53 0.0455168227302855 2.61506362646452e-45 16.4854452822363 -4.67848560779874 0.267781547081478 -1612.34520126987 4120.34352187158 -0.391313295289879 0.695724437287933 -32997.0093358022 20309.6108240801 -1.62469924321145 0.104826819374701 COL1A1 other 1 1 1 -0.391313295289879 -1.62469924321145 0.151441084997992 -1.77824455860032 5.42761989516193 -0.327628793642203 0.743322954197029 50.0719777513353 27.7383483489896 1.80515354127634 0.0716234404510477 SGCA other 1 1 1 -0.327628793642203 1.80515354127634 4.06029104909078e-33 120.252827437542 16.9691931224041 7.08653773754123 4.36028772412916e-12 -270.59974988349 37.7516830553381 -7.16788572013685 2.54216497772884e-12 PTGES3L-AARSD1 other 5.71364156428054e-29 3.7209668779017e-08 5.22362469350674e-08 7.08653773754123 -7.16788572013685 3.97103993918129e-56 314.135444369909 18.5237731061511 16.9585020594749 8.87219053119568e-52 -215.569212220752 81.5834168466346 -2.64231654609406 0.0084793756675396 MRPL27 essential 6.06894033905076e-52 1 1.36205869034916e-47 16.9585020594749 -2.64231654609406 3.54589642314343e-24 1099.94052434719 132.436924284463 8.30539164428652 8.20054066297794e-16 -929.942532816867 291.911155995615 -3.18570398464263 0.00152822130286591 VAT1 other 4.52562760485796e-20 1 1.06369212939487e-11 8.30539164428652 -3.18570398464263 1.5895911579979e-91 2088.69165659951 83.04859190857 25.150235646367 3.04212896962071e-92 1046.14045438367 366.309242806436 2.8558942339778 0.00446118627773923 LRRC59 other 2.47896741089773e-87 1 4.74785068288703e-88 25.150235646367 2.8558942339778 8.67988364839601e-17 78.7494375190032 12.922887030233 6.09379601746649 2.1129147030714e-09 -97.0311340833077 28.3568785021354 -3.42178473826027 0.000669785142225495 RND2 other 9.4732250138594e-13 1 2.31976905250209e-05 6.09379601746649 -3.42178473826027 3.25384235824126e-05 26.1166651321921 5.71714957428208 4.56812696482086 6.08611356426012e-06 15.4229663652275 10.5117548555959 1.46721138164833 0.142893264705735 ALOX12 other 0.188039549882762 1 0.0557305419079299 4.56812696482086 1.46721138164833 5.29525989261306e-21 219.829933738207 39.7028402118662 5.53688180908793 4.82392336360133e-08 -521.955143945522 92.6060056186614 -5.63629907648604 2.80909565715535e-08 HDAC5 other 6.39826252824436e-17 0.000378609912671399 0.000501398594412722 5.53688180908793 -5.63629907648604 1.91701947818634e-15 292.72248592814 36.787151745292 7.95719353199455 1.11654648439373e-14 -234.571997191294 178.313960570593 -1.31549989939475 0.188923905842299 ABCC3 other 2.00673598976546e-11 1 1.42013547350039e-10 7.95719353199455 -1.31549989939475 1.89538767509813e-53 464.35838332121 31.9432888245262 14.5369622355439 2.12147329627551e-40 -1041.77703362289 154.537972568327 -6.74123657965218 4.19961761612778e-11 LUC7L3 essential 2.88421142519683e-49 6.04031001727659e-07 3.20830406595745e-36 14.5369622355439 -6.74123657965218 3.44342882969082e-19 140.125353300451 22.1230377471327 6.3339110524554 5.06478573442379e-10 -215.512960804242 51.6880556568125 -4.16949250780799 3.55973436149596e-05 MPP2 other 4.00057561433479e-15 0.414246287647285 5.70244225838775e-06 6.3339110524554 -4.16949250780799 5.72739598469464e-32 181.248861564591 14.6193771590054 12.39785112548 4.37269061546717e-31 360.170581120777 62.7863471471199 5.73644745213208 1.64731869840041e-08 SMURF2 other 7.98169904427046e-28 0.000223705879242776 6.45540315561419e-27 12.39785112548 5.73644745213208 7.40389027500424e-25 320.781597658021 42.6812649908513 7.51574719556182 2.38466303861427e-13 -423.710524350751 94.9675705705406 -4.46163381673562 9.91379895348539e-06 DUSP3 other 9.55398001086547e-21 0.11971903616229 2.94458192008091e-09 7.51574719556182 -4.46163381673562 0.000661671818585946 11.3774575765816 5.50778876194913 2.06570332820013 0.0393475496138115 -64.9233663789884 22.9729107508856 -2.82608360268346 0.0048919840230484 CACNG1 other 1 1 1 2.06570332820013 -2.82608360268346 7.76042713560225e-56 707.90677817957 43.8108813015516 16.158240992849 3.38758773495076e-48 -111.649653509605 103.214795587669 -1.08172140315651 0.279859161284382 EFTUD2 essential 1.18509482787782e-51 1 5.18267047570116e-44 16.158240992849 -1.08172140315651 0.0573628680802685 -9.49803805109382 13.5578530549658 -0.700556202562984 0.48390587847044 -124.793536137048 52.2594632587938 -2.38796054064042 0.0173124215808026 HLF other 1 1 1 -0.700556202562984 -2.38796054064042 1.32981087136304e-11 339.089116952704 62.3504075017782 5.43844267486196 8.25726940822497e-08 -1281.12715659151 330.574790315499 -3.87545328356348 0.000119927109453743 SLC16A6 other 1.19736170857528e-07 1 0.000847822237256927 5.43844267486196 -3.87545328356348 3.63400610279507e-50 1477.22959480449 94.3594659626019 15.6553407730176 1.25616073972978e-45 -1792.64697361602 490.73884826193 -3.6529550899936 0.00028520651193132 PRKAR1A other 5.49752443230838e-46 1 1.91539389593997e-41 15.6553407730176 -3.6529550899936 0.072912789445283 34.9174035205707 16.5508339748131 2.10970659084054 0.0353397636594298 3.38848811862161 29.6068628448942 0.114449414528428 0.908923772242541 EFNB3 other 1 1 1 2.10970659084054 0.114449414528428 1.44240372211633e-06 22.7320959677587 7.23351625034986 3.14260660804615 0.00176888696262658 175.482922808033 37.4691096924407 4.68340252139582 3.5961208902768e-06 FAM20A other 0.00949055005984052 0.0444660348082727 1 3.14260660804615 4.68340252139582 1.17063601696811e-51 2831.6274599934 242.380109954972 11.6825900463509 2.93376552264698e-28 -2990.00678429738 453.450685847573 -6.59389626615862 1.02498130083564e-10 YWHAE other 1.77550364693553e-47 1.46469827889413e-06 4.27977714443742e-24 11.6825900463509 -6.59389626615862 1.02924369706532e-05 142.086263677746 30.4066750398088 4.67286421457542 3.82229581429657e-06 -35.851201243239 117.221703952215 -0.30584098366164 0.759852763159512 MMD other 0.0625265545967183 1 0.0354479713817864 4.67286421457542 -0.30584098366164 1.93384763040444e-38 72.0134038895531 18.0946292655662 3.9798220141815 7.82999088449467e-05 -341.052891151709 32.1826038226085 -10.5974299976348 5.49435977925551e-24 RANGRF other 2.81258799366022e-34 8.54153171283062e-20 0.653491039219925 3.9798220141815 -10.5974299976348 1.62365707238415e-62 258.919862652294 27.5668264782912 9.39244358998642 1.59933009766726e-19 -578.867367572331 50.689995176811 -11.4197558226864 3.18359293840375e-27 DPH1 essential 2.5009189885933e-58 4.97022529543593e-23 2.18868323865765e-15 9.39244358998642 -11.4197558226864 0.00515216311610147 8.12375426257082 7.74832541627922 1.04845290125565 0.294916109143058 85.6619231361373 26.5627110858113 3.22489383178566 0.00133924225918381 MAP2K6 other 1 1 1 1.04845290125565 3.22489383178566 8.54441578486969e-60 234.947445550752 15.8737888665057 14.8009682834134 6.73869736461199e-42 -165.241606761505 44.1286013590072 -3.74454665846274 0.000199979052490234 DHRS7B other 1.31225137624029e-55 1 1.02192345534341e-37 14.8009682834134 -3.74454665846274 1.55820104982663e-25 337.304617631856 32.9235485222891 10.2450869596727 1.91186601859392e-22 -131.748739150634 112.777484555589 -1.16821845840775 0.243287890730616 WSB1 other 2.02831030655933e-21 1 2.68578938292073e-18 10.2450869596727 -1.16821845840775 0.682852180066225 73.8528421166169 152.321426057311 0.48484867840477 0.627990650141828 246.646538280775 286.306407992284 0.861477533843469 0.389377571886166 MYH1 other 1 1 1 0.48484867840477 0.861477533843469 0.75477604372508 14.6803847191703 23.2744409619289 0.630751335474981 0.528477079826029 27.7181411964215 43.5499378929408 0.636467984513808 0.524748304526961 MYH3 other 1 1 1 0.630751335474981 0.636467984513808 4.41351816673339e-29 164.435688532921 14.193101426254 11.5856065277426 7.44724369006379e-28 -40.7076485613527 46.0312451243979 -0.884348195477694 0.376904788776039 NAT9 other 5.99135091134058e-25 1 1.08424420883639e-23 11.5856065277426 -0.884348195477694 6.92416635674226e-43 181.414718327491 12.0303297311228 15.0797793894349 4.21372154742425e-43 37.4129836421298 39.006558850798 0.959145967867513 0.337916853583795 TMEM104 other 1.02657690405061e-38 1 6.40359263562064e-39 15.0797793894349 0.959145967867513 0.638772578047966 0.949097069255916 39.2190359549844 0.0241999081860474 0.980702635466865 -128.453379029312 144.975519220445 -0.88603496452384 0.376017091657517 VTN other 1 1 1 0.0241999081860474 -0.88603496452384 2.03915351065366e-57 465.72445517847 27.2997841284536 17.0596387497827 6.9784364247029e-52 -110.699883470659 99.7794690358937 -1.10944550557627 0.267765030994039 TNFAIP1 other 3.12235185551288e-53 1 1.07160869737738e-47 17.0596387497827 -1.10944550557627 1.77440077187231e-61 172.431643338288 9.6092969570756 17.9442517083752 4.62394089489914e-56 -33.1432656813802 35.1933906330621 -0.941746875910388 0.346772524087183 IFT20 other 2.73080278791149e-57 1 7.12456813086059e-52 17.9442517083752 -0.941746875910388 2.00466841593841e-31 469.374434731392 38.2823510202826 12.2608570848408 1.99058042674247e-30 86.0193713228858 140.242133683001 0.613363252995861 0.539912878732762 TMEM97 other 2.78007415922339e-27 1 2.93073156229294e-26 12.2608570848408 0.613363252995861 7.96339416475237e-14 217.935816382865 27.3325713945096 7.97348384230847 9.3983385468948e-15 197.273683888369 85.7784590904742 2.2998044728257 0.0218434143854616 CDR2L other 7.86464807710944e-10 1 1.19716036410346e-10 7.97348384230847 2.2998044728257 5.24925182078411e-08 94.1977175290343 176.436361280642 0.533890615547223 0.593637323082692 -1590.86317213612 318.796832164888 -4.99021010131399 8.15203977210783e-07 PMP22 other 0.000388287157183401 0.0103962963213691 1 0.533890615547223 -4.99021010131399 2.07092810707587e-11 5.73632893224606 1.37287843793978 4.17832254751871 3.45404534032456e-05 -20.930970744099 5.06728069629292 -4.13061205774756 4.22634980782748e-05 FOXN1 other 1.84851042837592e-07 0.489791679229127 0.297807789242783 4.17832254751871 -4.13061205774756 2.67232042586569e-42 159.490855539335 12.6895382632694 12.5686886496879 9.29087004850792e-32 -185.593347750303 46.8369598570066 -3.96254044491615 8.47064765574973e-05 UNC119 other 3.95182744577018e-38 0.959724379396444 1.37430549757529e-27 12.5686886496879 -3.96254044491615 5.63652366763594e-12 172.893830196628 23.5657193562656 7.33666677358014 8.65934779607133e-13 279.972030286584 86.9808363859659 3.21877831852806 0.00136915391037192 ALDOC other 5.17376507452303e-08 1 1.05340965939208e-08 7.33666677358014 3.21877831852806 4.20944772098991e-74 919.162365842695 50.6316793071903 18.1538984766038 3.3360300206642e-57 -1095.07187463742 191.862858808873 -5.70757613764261 1.94426075431632e-08 SUPT6H essential 6.52801152571115e-70 0.000263291791349516 5.14682711588072e-53 18.1538984766038 -5.70757613764261 3.75116735822975e-10 135.391875259399 35.9746321360403 3.76353744903924 0.000186878886945203 -568.963625785383 139.698656806862 -4.07279238605704 5.38008710666131e-05 RAB34 other 3.14272801272488e-06 0.619463229460983 1 3.76353744903924 -4.07279238605704 5.05071095852156e-49 279.632614391229 24.4514097657534 11.4362573393572 3.95696514494607e-27 -668.289140204485 87.5646153886205 -7.63195426872545 1.13864159163454e-13 PHF12 essential 7.61647212545052e-45 1.68997185030399e-09 5.73562097759933e-23 11.4362573393572 -7.63195426872545 1.66380709539158e-28 384.50152559908 54.7571069271624 7.02194741790398 6.51655992056271e-12 -584.067369454094 113.557244006632 -5.14337393940262 3.76538160417034e-07 TMEM33 other 2.2443093909737e-24 0.00486600264706933 7.76773942531076e-08 7.02194741790398 -5.14337393940262 1.07160842862378e-18 187.317805313368 44.7787919000201 4.18318130894648 3.36023962434045e-05 -588.670824023844 99.4082647193249 -5.92174932019919 5.7068175932066e-09 SLAIN2 other 1.22999215437437e-14 7.85372237177092e-05 0.290055884373068 4.18318130894648 -5.92174932019919 1.97089796470881e-31 289.341956051801 81.7390493169492 3.53982531568059 0.000435547161306541 -1729.23059114327 180.164480184009 -9.59806610813154 3.18415950651883e-20 OCIAD1 other 2.73363547705112e-27 4.90710821549616e-16 1 3.53982531568059 -9.59806610813154 0.109148217106014 -13.5865692724801 6.66173117228353 -2.03949527849574 0.0419085107631658 -23.0877634946473 19.072957896622 -1.21049727157088 0.226641246464943 UGT2B10 other 1 1 1 -2.03949527849574 -1.21049727157088 0.364100332068693 2.69433398858481 11.8643798252756 0.227094380680975 0.820438086733047 35.9490749980045 26.249460204093 1.36951673362026 0.171418887234943 CWH43 other 1 1 1 0.227094380680975 1.36951673362026 6.33188859313347e-12 117.315738841869 24.0277966829128 4.88250089635962 1.39899224561256e-06 -188.732391916534 57.7228079869585 -3.26963289726263 0.00114873589531605 DCUN1D4 other 5.797477195873e-08 1 0.0133365930774246 4.88250089635962 -3.26963289726263 2.57557607129887e-16 125.267323585505 22.9457275814904 5.45928749221944 7.42053705446344e-08 -246.130642085186 56.6657131100902 -4.34355501018761 1.68673618797231e-05 USP46 other 2.77389542878888e-12 0.200940882073141 0.000764018495127556 5.45928749221944 -4.34355501018761 0.772873499519343 -5.56746633458848 8.16657164600182 -0.681738503734819 0.49569659668832 -0.746562599377549 21.3815684184619 -0.034916175687698 0.972159484723501 SULT1E1 other 1 1 1 -0.681738503734819 -0.034916175687698 0.0300888985676744 -2.12225878099462 19.3777273958477 -0.109520520009451 0.912830409348022 133.143666330474 54.2090807850522 2.45611370645464 0.0143592607384692 ODAM other 1 1 1 -0.109520520009451 2.45611370645464 0.841885387012771 -27.1427051797065 61.3598788097906 -0.442352653007124 0.658412140923341 -87.7667762281132 169.567087827352 -0.517593227274592 0.604955254863772 SMR3A other 1 1 1 -0.442352653007124 -0.517593227274592 1.7377321396428e-09 45.274470180222 7.09172960747736 6.38412244771509 3.77947998907711e-10 21.4774113089537 17.6827053746739 1.21459985075105 0.225061659170192 CHIC2 other 1.40599907418499e-05 1 4.27723750363857e-06 6.38412244771509 1.21459985075105 0.000913802142745001 23.9525547778482 7.72963187381234 3.09879631641948 0.0020456089493744 58.3663441504252 18.9536687263989 3.07942198383639 0.00218092484772498 NMU other 1 1 1 3.09879631641948 3.07942198383639 0.0310685146331779 29.5249001642233 14.6258290957659 2.01868215271096 0.0440195849428575 -31.9028347685244 35.7521886690134 -0.892332356597085 0.372616738199073 KIAA1211 other 1 1 1 2.01868215271096 -0.892332356597085 1.05200752296119e-32 136.417068394256 26.7276968120724 5.10395898881338 4.6049155694269e-07 -534.027502495591 59.1872323373119 -9.02268076081228 3.1464964846633e-18 LAMTOR3 other 1.47565095245766e-28 4.81539822012871e-14 0.00452893446253136 5.10395898881338 -9.02268076081228 2.26398007421559e-06 185.789921668587 59.2969705491422 3.13321102154137 0.00182252972799127 -342.296865275198 134.131462203228 -2.55195059870868 0.0109854237930115 NFKB1 other 0.0146411591399522 1 1 3.13321102154137 -2.55195059870868 1.28285127338683e-05 869.963771564861 207.880744557918 4.18491752766681 3.3307374655568e-05 -511.903341245476 636.053816365648 -0.804811366702339 0.421283393773355 AREG other 0.0772404751706209 1 0.287675794900141 4.18491752766681 -0.804811366702339 7.43248738095787e-11 157.303071124478 46.8628609856364 3.35666811236071 0.000844307232833586 -461.189240598212 106.21466531512 -4.34204861663824 1.68551057491442e-05 MANBA other 6.45585853910001e-07 0.200811729895304 1 3.35666811236071 -4.34204861663824 1.82471120915009e-40 960.435936821697 96.6920441343495 9.93293652461429 1.81852382404115e-21 -1361.65417449934 219.182360755395 -6.2124258987197 1.04281440402759e-09 UBE2D3 essential 2.67721628606501e-36 1.46025300995983e-05 2.53356739165412e-17 9.93293652461429 -6.2124258987197 2.75581341305316e-06 66.9089785738928 14.9290137180715 4.48180836573951 9.02897033451067e-06 -20.9384270409265 36.520888540678 -0.573327426511124 0.56665993892987 MAPK10 other 0.0176620081642577 1 0.0816580077053145 4.48180836573951 -0.573327426511124 2.26294389186976e-19 75.1054649541922 21.1274076243274 3.55488313046563 0.000411383632854626 -326.330500596249 46.4385664461507 -7.02714415128761 6.39516309429418e-12 ELF2 other 2.64560770398494e-15 9.31199698160175e-08 1 3.55488313046563 -7.02714415128761 2.36604902950998e-16 156.653965918157 27.1766130366044 5.76429320707326 1.38134096592744e-08 -240.394002614039 59.7348701138557 -4.02434963290025 6.53102826353807e-05 NDUFC1 other 2.55107406361766e-12 0.746561840805037 0.000147085186051954 5.76429320707326 -4.02434963290025 0.299843986437357 -22.0762903573181 17.9876108222036 -1.22730531450388 0.220242629908715 -54.083999777212 40.3866386086276 -1.339155761422 0.181083369986689 UCP1 other 1 1 1 -1.22730531450388 -1.339155761422 1.87587300844609e-15 73.8492588754622 727.437811174134 0.10151968696302 0.919175613764329 -13193.5604009367 1663.65082579421 -7.93048649174219 1.26258135759986e-14 TBC1D9 other 1.96460180174559e-11 1.88957925978394e-10 1 0.10151968696302 -7.93048649174219 7.63544086104511e-32 111.243908746121 12.4084083557036 8.96520371970083 5.05548581159987e-18 -155.933311198799 28.438784578474 -5.48312150150146 6.42576603703794e-08 ZNF330 other 1.06254795022304e-27 0.000855719263152342 6.79811177085834e-14 8.96520371970083 -5.48312150150146 7.95771302847816e-14 -160.794432501071 104.36426388618 -1.54070393939091 0.123980093627071 -1892.49796623113 239.869154234916 -7.88970958882737 1.71881859689533e-14 INPP4B ts 7.85983315822788e-10 2.56963380235852e-10 1 -1.54070393939091 -7.88970958882737 3.30482296160423e-14 170.280583466708 35.8729321475204 4.74677070629361 2.65676997690259e-06 -375.809335395122 82.6754367658572 -4.54559842797614 6.77915298410614e-06 GAB1 other 3.31275453671208e-10 0.0827056664060949 0.0249072185334618 4.74677070629361 -4.54559842797614 0.00825797751736738 10.5875739319388 18.0846079376579 0.585446694141052 0.558491971077141 -104.044882086667 39.6834437202417 -2.62187129776733 0.00899153579854913 KLHL2 other 1 1 1 0.585446694141052 -2.62187129776733 0.00369850965283094 47.0661535846158 272.00449501142 0.173034469826095 0.862689170836944 -1824.59896326932 596.865307041674 -3.05696937272638 0.00234653513539199 CPE other 1 1 1 0.173034469826095 -3.05696937272638 2.71665952785988e-07 -311.220855639465 266.080402831643 -1.16964967102964 0.242656074043828 -3146.34128604807 575.859473668805 -5.4637310488316 7.11716649251062e-08 RPL34 essential 0.00190139000354913 0.000946511971838987 1 -1.16964967102964 -5.4637310488316 1.0322684706966e-29 244.561930847209 103.259924522515 2.36841090072543 0.0182132051493237 -1846.86208067045 198.39923306845 -9.30881663253841 3.16066333234921e-19 WFS1 other 1.40894323565379e-25 4.85256641415574e-15 1 2.36841090072543 -9.30881663253841 2.60235677877648e-26 239.780297081578 27.4358256774916 8.73967854659079 2.92811421534315e-17 -116.69686430793 53.0232638391543 -2.20086158147354 0.0281667458332486 GRPEL1 essential 3.42366057815833e-22 1 3.89409909498486e-13 8.73967854659079 -2.20086158147354 4.26145987362559e-14 118.790881051747 15.6873048211304 7.57242129264542 1.58505710296435e-13 17.5847828654984 34.2300605054292 0.513723394170141 0.607654367917068 GAR1 essential 4.24952778597944e-10 1 1.96531230196549e-09 7.57242129264542 0.513723394170141 3.41158927747535e-17 58.4069928068983 9.72388569767672 6.00654868051906 3.55929813972573e-09 -76.6178899158285 21.1705996202998 -3.61907037542583 0.000324506567699488 FRG1 other 3.76844151589927e-13 1 3.87429602509145e-05 6.00654868051906 -3.61907037542583 1.95380210958887e-17 442.741960650261 100.245899787279 4.41655929658726 1.21242128112074e-05 -1126.89139079888 210.711060126974 -5.34804100990151 1.31584383468853e-07 CLCN3 other 2.17126028438611e-13 0.00173230840836745 0.108511704660306 4.41655929658726 -5.34804100990151 0.000229772287693734 71.1063537492852 18.4427544682754 3.85551702006336 0.000129396943237757 116.149055523755 38.8076561350765 2.99294178240188 0.00288943235649451 AADAT other 1 1 1 3.85551702006336 2.99294178240188 1.7684514845795e-11 -126.917933066575 212.39758257193 -0.597548858747452 0.550391022369223 -3107.91250647557 458.978868594413 -6.77136295183546 3.3324271999268e-11 GALNT7 other 1.58294092384711e-07 4.80136110965454e-07 1 -0.597548858747452 -6.77136295183546 8.14539841924471e-16 497.532304199647 102.08397633799 4.87375513814594 1.44010666316216e-06 -678.248910059926 185.901237561176 -3.64843676652088 0.000289341453040826 DHX15 essential 8.63656594392516e-12 1 0.0137170159666195 4.87375513814594 -3.64843676652088 0.615190893375962 -44.457058088695 68.4184803748412 -0.649781431056788 0.516109211238846 38.6694758790459 124.503187840956 0.310590247122374 0.75623176417141 SOD3 other 1 1 1 -0.649781431056788 0.310590247122374 1.67471727552032e-34 14.4570643665268 14.6747107407099 0.985168608906248 0.32498163940996 -293.626472702333 26.5979314565914 -11.0394476796641 1.07899522419762e-25 SEPSECS essential 2.38111302233479e-30 1.68172195643442e-21 1 0.985168608906248 -11.0394476796641 0.0305982738440641 -41.6272938025381 21.2178497356191 -1.96189973636476 0.0502855010590413 -114.966656402452 46.7970385354388 -2.45670794564038 0.014334056192608 CPZ other 1 1 1 -1.96189973636476 -2.45670794564038 4.73170772033544e-10 267.199568248906 98.6791600595601 2.70776086954562 0.00698657729690832 1495.03684869169 223.849453613481 6.67876032109135 5.95494831003542e-11 TRIM2 other 3.94766375107586e-06 8.54535082490083e-07 1 2.70776086954562 6.67876032109135 0.993903859108849 0.362258856541578 6.04576023809574 0.0599194877525742 0.95224184520581 1.48006097725495 13.4967965265137 0.109660168199724 0.912719480031766 SLC2A9 other 1 1 1 0.0599194877525742 0.109660168199724 5.67644039046076e-08 103.169273526853 17.8071504285931 5.79369921878084 1.1706521910341e-08 54.8427927646402 40.0461410050688 1.36949007790035 0.171415377640022 FBXW7 ts 0.000418978065219909 1 0.000124990534436711 5.79369921878084 1.36949007790035 4.22266059975262e-16 46.2369940349798 5.94205102212732 7.78131891880432 3.68437399325113e-14 84.1861032712169 12.2350720658856 6.88071985337532 1.65843891953554e-11 NEIL3 other 4.51613551143542e-12 2.39992696045988e-07 4.63641623310722e-10 7.78131891880432 6.88071985337532 8.81178600295845e-16 4.26490933867775 5.3179909512554 0.801977547116914 0.42291612911085 -67.3619102916709 9.6550295826003 -6.97687249069297 8.80333914780509e-12 TBC1D19 other 9.33520609153418e-12 1.27877304461017e-07 1 0.801977547116914 -6.97687249069297 1.66730561370729e-16 659.831533887231 77.4101035307146 8.52384254499058 1.58193169473001e-16 312.594439992686 169.555733059162 1.84360879076625 0.0657930233980584 NSD2 other 1.80369121290855e-12 1 2.07818366736682e-12 8.52384254499058 1.84360879076625 2.890846714621e-09 122.278289545694 96.4019267319942 1.26842163524011 0.205198040298438 -1154.15300122051 216.642075150288 -5.32746466917777 1.46860799547426e-07 SH3D19 other 2.30891927096779e-05 0.00193004462765227 1 1.26842163524011 -5.32746466917777 5.50445027151158e-08 46.6841628081865 19.4299973770227 2.40268497737389 0.0166091708478593 -119.451308913329 35.1344376838853 -3.39983551147359 0.00072372658363849 STIM2 other 0.00040672383056199 1 1 2.40268497737389 -3.39983551147359 0.166847397484584 -0.00276387090315919 2.48658671084185 -0.00111151197386697 0.999113550159666 7.91285389902711 4.76745309750632 1.6597654423 0.097539012760188 NKX3-2 other 1 1 1 -0.00111151197386697 1.6597654423 2.64373984889142e-14 556.181712513734 86.4884873514811 6.43070227663323 2.79479510373715e-10 -192.223136258339 169.188675042869 -1.13614659024686 0.256398251062013 MFSD10 other 2.65695854813588e-10 1 3.17600515588689e-06 6.43070227663323 -1.13614659024686 4.72217393181962e-06 36.3954714926257 33.1450198209918 1.09806757362611 0.272661647721407 -304.736933423946 73.9418853713599 -4.12130326260223 4.35611519158747e-05 GLRB other 0.0295608088131908 0.50452526148966 1 1.09806757362611 -4.12130326260223 0.685025392705447 4.26720973603954 6.51970961214418 0.654509171404054 0.51306043483211 10.2035188585962 12.454936683858 0.819234904005596 0.413011156995469 BST1 other 1 1 1 0.654509171404054 0.819234904005596 6.5248732376567e-05 74.1481380386998 25.1554460271427 2.94759782667713 0.00334048284465226 -108.824054346376 56.1375395800829 -1.93852554209529 0.0530779625945943 RAPGEF2 other 0.363580798687855 1 1 2.94759782667713 -1.93852554209529 2.72739774958525e-11 45.0903421064124 20.7721383148716 2.170712587357 0.0303830765576955 -227.422639308844 43.8512415268666 -5.18623034126655 3.02836631308063e-07 SNX25 other 2.42002002320699e-07 0.00392718543480297 1 2.170712587357 -5.18623034126655 9.29358411005899e-13 2.02732744362071 2.79010635441118 0.726612962411089 0.467774473882392 -38.513520412118 5.89008342705552 -6.53870541717795 1.42737776800501e-10 LRP2BP other 8.7908012097048e-09 2.03444153273754e-06 1 0.726612962411089 -6.53870541717795 1.51687992356414e-29 83.4679802888429 15.2061317859244 5.48910015143401 6.1947037951455e-08 -242.156285697966 32.1356028996389 -7.53545176837765 2.03439888630767e-13 UFSP2 other 2.0655353919173e-25 3.01050347195809e-09 0.000640532372418045 5.48910015143401 -7.53545176837765 2.48757259740675e-08 12.0068303085479 50.6155100546585 0.237216424285403 0.812577710973336 -488.473659981348 96.6984909322334 -5.05151275135898 5.98287224457236e-07 KLF3 other 0.000187911234008106 0.00767482851533742 1 0.237216424285403 -5.05151275135898 9.89353865011852e-05 -104.520734263281 63.9990804613091 -1.63315993776612 0.103009748298402 -544.435705790876 126.998880091058 -4.28693312413871 2.14060804890605e-05 KLHL5 other 0.537812761020443 0.253191120024608 1 -1.63315993776612 -4.28693312413871 0.227511591838769 9.43143300889515 6.83280402324925 1.38031662796179 0.168057145306725 -4.86102547769457 14.3465457294732 -0.338828981509339 0.73486955192318 FAM149A other 1 1 1 1.38031662796179 -0.338828981509339 9.01980717545848e-15 265.755419255534 38.893983412543 6.83281566808687 2.24160313214833e-11 535.63865610013 71.9284685911646 7.44682413780634 3.77979265447346e-13 NCAPG essential 9.22996868264667e-11 5.57784002020649e-09 2.632538718395e-07 6.83281566808687 7.44682413780634 2.85234417137268e-10 577.798036112611 302.184441618563 1.91207076386131 0.0563892032870168 -2871.37862918022 612.145780017272 -4.69067781386846 3.44395398475692e-06 UGDH other 2.40566707413572e-06 0.042632706377306 1 1.91207076386131 -4.69067781386846 0.127011411231653 3.24657480477321 27.7017063190682 0.117197647227184 0.906746926594286 90.4577225506488 50.0832523446694 1.80614713134293 0.0714509776826835 PPARGC1A other 1 1 1 0.117197647227184 1.80614713134293 4.70780637527676e-05 2088.72345167279 467.091718826507 4.47176296963768 9.44791207675468e-06 1790.61028706032 863.566798564325 2.07350524596036 0.0385953225852725 CRYAB other 0.267414701516195 1 0.0852957502289413 4.47176296963768 2.07350524596036 2.08644110164923e-15 340.536378345067 41.0102841429853 8.30368248992771 8.07085611413368e-16 125.428120572383 109.755294399307 1.14279790563958 0.253626126609135 HTATIP2 other 2.1817914599946e-11 1 1.04695145512542e-11 8.30368248992771 1.14279790563958 2.08523620934412e-06 395.396364906167 113.279437610313 3.49045134092519 0.000522468178394318 -406.07477882321 256.975784563306 -1.58020639770894 0.114657316880837 CTSC other 0.0135331829986433 1 1 3.49045134092519 -1.58020639770894 2.20715388996117e-15 165.068881677565 22.285075991465 7.40714914953776 5.05670464704869e-13 -80.9741701122998 56.5376477079794 -1.43221682179875 0.152665766147006 CCDC34 other 2.30647581500942e-11 1 6.18788947659348e-09 7.40714914953776 -1.43221682179875 0.00271350096421139 -14.5722147977112 14.471818270928 -1.00693738166855 0.314410894806992 -88.1847103691383 26.7378429060936 -3.29812358756289 0.00103670287179022 ZBTB16 other 1 1 1 -1.00693738166855 -3.29812358756289 1.142711788371e-31 61.7665814446292 5.61742502778271 10.9955328534237 1.7733387333543e-25 -64.4663576482564 17.6833888798742 -3.64558841555685 0.000293036309487229 ELP4 other 1.58802657229918e-27 1 2.54669175497011e-21 10.9955328534237 -3.64558841555685 8.85563955027942e-38 213.765122150889 22.6243224215847 9.44846515920168 1.0052729156718e-19 -138.104781913161 41.6576626246335 -3.31523117745678 0.00097658511808238 ZPR1 other 1.2835363964175e-33 1 1.37812864009447e-15 9.44846515920168 -3.31523117745678 5.22306255545767e-34 576.13560912332 51.5985701020394 11.1657281971957 3.55660011865686e-26 -457.273839956694 146.036917560813 -3.13122084192358 0.00183559018980383 MTCH2 other 7.39637888478361e-30 1 5.12861737110319e-22 11.1657281971957 -3.13122084192358 5.908831676287e-14 135.165417084478 32.1754760946242 4.20088320331213 3.1193802978603e-05 -470.663979584657 92.9358017082351 -5.06439898223799 5.6640435556041e-07 FNBP4 essential 5.86392455554722e-10 0.00727093271232898 0.270294302809595 4.20088320331213 -5.06439898223799 0.73061675827106 -5.13518337323047 7.1952043232443 -0.713695281264095 0.475723396027597 -9.07887260901912 12.9653955490617 -0.70023876823998 0.484079217473065 TECTA other 1 1 1 -0.713695281264095 -0.70023876823998 4.2747491656404e-12 49.0491779775415 60.6619813812475 0.808565379183346 0.419119947328828 -597.122534100625 108.970521126164 -5.47967035423539 6.53562058170082e-08 SC5D other 3.93960883105419e-08 0.000870021811836014 1 0.808565379183346 -5.47967035423539 0.585922924336999 -0.472316010079926 2.21132121472961 -0.213589960126023 0.830946707719749 -3.76023318493172 3.99610329724669 -0.94097497117317 0.347134567035074 CRTAM other 1 1 1 -0.213589960126023 -0.94097497117317 0.493919487154585 2.76804033042507 22.1327027007048 0.125065626546229 0.900520780713029 -34.8185356545474 39.6877088584908 -0.877312816889865 0.380729022434123 B3GAT1 other 1 1 1 0.125065626546229 -0.877312816889865 6.15760315147667e-06 4555.18934225835 1008.32037719564 4.5176011962858 7.67343143497669e-06 1891.36201256576 1813.67352372633 1.04283488060178 0.297487126134142 HSPA8 other 0.0380786178887317 1 0.0697207980181982 4.5176011962858 1.04283488060178 1.32294741505971e-13 -117.649743921424 55.0045325455922 -2.13890998571629 0.0328842992568184 -739.336476476824 99.4177606627457 -7.43666394765088 4.00589284300799e-13 VWA5A other 1.296091582534e-09 5.91029430057399e-09 1 -2.13890998571629 -7.43666394765088 1.61779454773164e-10 64.1357204244311 27.0036245309459 2.37507821777525 0.0179000797825349 -315.637423790113 64.3530738217194 -4.90477618310105 1.24606875363706e-06 DNAJC4 other 1.382890779401e-06 0.0157540472522334 1 2.37507821777525 -4.90477618310105 1.40603168730522e-39 57.7106755482276 49.2696551416337 1.17132290417558 0.241984631595323 -985.832654118433 88.6209292878125 -11.124151620175 4.99027970169796e-26 SIAE other 2.05547772367151e-35 7.7818421668278e-22 1 1.17132290417558 -11.124151620175 2.60781144289477e-14 19.6296698950971 12.4346762102709 1.57862332425538 0.115025932039448 -200.597145855856 29.7045546348383 -6.75307703891949 3.85466100745839e-11 SNX15 other 2.62111128125353e-10 5.54801358803486e-07 1 1.57862332425538 -6.75307703891949 0.183985506218588 1.1583219300209 16.6948291966279 0.0693820773113908 0.944711131905437 -66.9995199091466 41.2151595896267 -1.62560379666732 0.104616320884768 LPXN other 1 1 1 0.0693820773113908 -1.62560379666732 0.000357894944251919 56.6630458832358 41.6927681210252 1.35906173748778 0.174694356625705 -292.435327527474 104.12515816375 -2.8084982792303 0.00515748718782704 DTX4 other 1 1 1 1.35906173748778 -2.8084982792303 3.04216064869235e-13 13.5762619159245 23.0336102497822 0.58941094204079 0.555839185623148 -375.787089629387 54.4511983577123 -6.90135572702528 1.48979278281515e-11 ATG2A other 2.93751032237733e-09 2.15781586662946e-07 1 0.58941094204079 -6.90135572702528 2.66250809541536e-19 187.301014419746 46.6266603676072 4.01703688282744 6.749139766617e-05 -705.300347516116 110.009274910211 -6.41128075875222 3.20458154017377e-10 EHD1 other 3.1063481949211e-15 4.53736700273203e-06 0.566657774805163 4.01703688282744 -6.41128075875222 3.06515807325169e-25 151.877485232761 58.3718255458941 2.60189712780781 0.00952828248524124 -1252.37479587534 144.564801230971 -8.66306863919401 5.47582231678511e-17 OSBP other 3.97275137874152e-21 8.33146365498855e-13 1 2.60189712780781 -8.66306863919401 2.0735849160731e-10 183.579237990061 30.3292090335806 6.05288577710028 2.79075177938424e-09 -188.525553714953 120.211420501133 -1.56828322075419 0.117446398473941 UNC93B1 other 1.76524283905303e-06 1 3.05029169486697e-05 6.05288577710028 -1.56828322075419 8.57856075770021e-89 68.7054413986142 3.59120985755241 19.1315584785793 7.56289695411829e-63 -100.328113994706 12.3669444058516 -8.11260329974753 3.28083446185078e-15 PUS3 other 1.33696869408758e-84 4.93535928096212e-11 1.17028267468026e-58 19.1315584785793 -8.11260329974753 5.32233976593494e-30 136.122834428435 14.5001895746893 9.38765894937282 1.67225751132557e-19 -42.241902418857 26.9942586266488 -1.56484765901871 0.118201202616956 DCPS other 7.28042856582241e-26 1 2.28798272699564e-15 9.38765894937282 -1.56484765901871 3.46488247608047e-30 412.277289000226 35.834243965583 11.5051203367426 2.57864471977969e-27 -254.630978157756 134.286794303788 -1.89617288489084 0.058518058205133 KMT5B other 4.74862143346828e-26 1 3.74264494628824e-23 11.5051203367426 -1.89617288489084 6.71066646619916e-37 129.92696585991 14.6139178133727 8.89063203441715 8.8906233980118e-18 -111.292825350714 27.1850022479631 -4.09390532086689 4.88449653272254e-05 FOXRED1 other 9.67745211090582e-33 0.564012814633472 1.19161025403552e-13 8.89063203441715 -4.09390532086689 1.7270626360881e-41 706.588407948075 49.867135412924 14.1694204428865 1.64034940229248e-38 -391.735686109137 219.093938846401 -1.7879804807552 0.0743894782072544 PPP6R3 other 2.54551761933025e-37 1 2.472170584195e-34 14.1694204428865 -1.7879804807552 0.877048050562138 -9.22033686068247 18.9352117968553 -0.48694131122493 0.626500480461884 -15.0063436259096 44.2997256672032 -0.338745746162021 0.734934931925302 NRXN2 other 1 1 1 -0.48694131122493 -0.338745746162021 0.835434904452678 -20.1351978664838 34.8477140778181 -0.577805414195034 0.563636796420642 -34.2558267088781 91.0888263416239 -0.376070568528388 0.707012407921182 MS4A6A other 1 1 1 -0.577805414195034 -0.376070568528388 0.553819150066746 13.6651365830901 12.5713706869365 1.0870045059836 0.277520672065477 15.2756137762453 32.9992928032876 0.462907307356703 0.643617642406855 MS4A4A other 1 1 1 1.0870045059836 0.462907307356703 0.00114309980081939 210.950723790438 61.245274087373 3.44435920867125 0.000616548852516452 86.0117008500684 113.907908018238 0.755098591015268 0.450516612201941 ST3GAL4 other 1 1 1 3.44435920867125 0.755098591015268 6.43308701697448e-08 188.702633504024 38.2205728363507 4.93720055719714 1.08315259302034e-06 -669.887385190606 289.52242790534 -2.3137668125995 0.0210867629026819 CPT1A other 0.000471931263565248 1 0.0104025975033673 4.93720055719714 -2.3137668125995 2.31691199388966e-24 4524.37501674334 422.069702857461 10.7194972444428 3.31846069105684e-24 -4178.37436012217 4078.96953170677 -1.02437008358182 0.306171153449271 CCND1 og 2.96587904337815e-20 1 4.72947017689421e-20 10.7194972444428 -1.02437008358182 1.29389762371438e-19 193.954106624818 25.2788496149654 7.67258437701989 8.21244245273945e-14 -154.382302119497 63.341839702765 -2.43728794180821 0.0151276068616583 CCDC86 essential 1.52058848738914e-15 1 1.02450219597925e-09 7.67258437701989 -2.43728794180821 3.25255874464383e-24 487.306701135442 100.410461313009 4.85314672159867 1.60813201621609e-06 -1780.83707644786 251.381903910163 -7.08418962840014 4.5593728387027e-12 PRPF19 essential 4.15384277278463e-20 6.64938934796402e-08 0.0152836866821177 4.85314672159867 -7.08418962840014 1.90770959132993e-18 350.630779635555 69.8546716754107 5.01943207556409 7.12947160115212e-07 -924.38614673105 174.896653002199 -5.28532782568131 1.84968518442773e-07 TMEM109 other 2.17726895658485e-14 0.00241827841012081 0.00692271692471871 5.01943207556409 -5.28532782568131 0.0431487602956566 -0.56304134334434 6.07027848741258 -0.0927537911995093 0.92613312265747 31.0126743531497 13.6778233320424 2.26736912740332 0.0237570390896365 CCKBR other 1 1 1 -0.0927537911995093 2.26736912740332 0.17162032850011 32.943671215911 151.965276146515 0.216784202623689 0.828457796485423 -547.147191707343 337.787293121545 -1.61979802925998 0.105855188095892 HPX other 1 1 1 0.216784202623689 -1.61979802925998 1.18212593328372e-12 115.148658881037 48.1356571119463 2.39216966776297 0.0170875243108199 -603.694640147289 107.278010004557 -5.62738477458378 2.93220185889462e-08 TRIM3 other 1.11391726693325e-08 0.000395026234430283 1 2.39216966776297 -5.62738477458378 8.15660669437995e-40 275.86723664898 21.6440402495643 12.7456442266842 1.18725087336183e-32 17.7662797264667 49.758397483324 0.357050882364548 0.721195564454979 CHORDC1 essential 1.19396408792334e-35 1 1.76128667063227e-28 12.7456442266842 0.357050882364548 0.016800915303113 123.47208748869 43.6579134469601 2.82817197937543 0.00486784580781229 73.031164575345 122.360116973399 0.596854321340848 0.550872656534902 FOLR1 other 1 1 1 2.82817197937543 0.596854321340848 7.6912656696252e-33 171.564164463024 14.4403712574626 11.8808693629924 7.25825456797274e-29 -64.0363857374396 47.0984931286178 -1.35962705988422 0.174557126303935 ANAPC15 essential 1.08039208861225e-28 1 1.06159231311169e-24 11.8808693629924 -1.35962705988422 1.2680207779471e-42 186.900125082042 16.4651467167553 11.351257799109 6.47807964960429e-27 -77.3882621283277 33.4878250206221 -2.31093724601915 0.0212142023460104 PANX1 other 1.8770511575951e-38 1 9.38025933262701e-23 11.351257799109 -2.31093724601915 2.06073691569399e-19 291.398444172834 37.5371683301287 7.76293090651026 4.75129844982433e-14 -310.681123434923 120.241825078873 -2.58380246001032 0.010055516272806 ARHGEF17 other 2.4108561176704e-15 1 5.96335468437451e-10 7.76293090651026 -2.58380246001032 1.69991936408276e-23 68.7801685891747 19.5047849714617 3.52632283256698 0.000456734771708272 -230.175664394251 36.4953748526216 -6.30698178395932 5.87261642853719e-10 CEP164 other 2.14716814877294e-19 8.27158023959463e-06 1 3.52632283256698 -6.30698178395932 2.59106997462239e-14 230.371945213224 62.1316517641946 3.70780332844753 0.000230665939713654 -675.541735888688 131.497899512739 -5.13728157173527 3.89987464755215e-07 RNF141 other 2.60506175248535e-10 0.00503629811984885 1 3.70780332844753 -5.13728157173527 0.00229922531628551 -58.7684357352538 33.3649696059733 -1.76138136582425 0.0787376656204433 -236.835063184626 67.7232785201205 -3.49709979138506 0.000508934409570648 CEP126 other 1 1 1 -1.76138136582425 -3.49709979138506 3.00239564246167e-14 3128.17398039718 558.922593933504 5.59679285530787 3.48872681118914e-08 -3787.57182981046 1189.83908944087 -3.18326390805527 0.00154075475780598 EIF4G2 essential 3.01230354808179e-10 1 0.000364816162646048 5.59679285530787 -3.18326390805527 0.80473634378942 7.8331725798813 29.2170438780611 0.2681028447838 0.78872141223364 -18.6649547318363 54.845628327829 -0.340318003474592 0.733747950694373 IL10RA other 1 1 1 0.2681028447838 -0.340318003474592 0.0016654776017235 41.8065889823 20.0011113026877 2.09021330613175 0.0370657579229685 -79.0964741818745 42.7742122608952 -1.84916261460145 0.0649806540197089 GALNT18 other 1 1 1 2.09021330613175 -1.84916261460145 1.63432581302365e-23 227.395898861432 40.8416139405059 5.56775006963927 4.06526176774466e-08 -370.970257919879 82.2250042307223 -4.51164778148191 7.89269421503124e-06 BIRC2 other 2.06513409733669e-19 0.0959120201010596 0.000423844191905059 5.56775006963927 -4.51164778148191 9.70125114436154e-43 360.408965493799 48.5266752645229 7.42702778480455 4.29991685992962e-13 -595.905571889387 89.3321877406559 -6.67067030328851 6.25665462193436e-11 UBE4A other 1.43724035703716e-38 8.97329405877825e-07 5.26825813678576e-09 7.42702778480455 -6.67067030328851 7.11728576514184e-26 461.161875470539 110.163928171007 4.18614226205406 3.3096844752544e-05 -1279.22803573769 203.302718509349 -6.29223280985722 6.44984941681397e-10 DDX6 essential 9.31510360941764e-22 9.07751806922399e-06 0.286024988563405 4.18614226205406 -6.29223280985722 3.89605860323389e-07 18.8479494508456 3.77245380646142 4.99620417314666 7.90510698321713e-07 6.52244627510764 6.98371623459834 0.933950644041707 0.350746004520248 UPK2 other 0.00269451412999656 1 0.00765688662394411 4.99620417314666 0.933950644041707 2.56807933872892e-13 137.399556068924 34.5538109028258 3.97639370242915 7.9422436284619e-05 -207.398972722045 63.8573265385707 -3.24784929097796 0.00123450614511348 CBL other 2.48744164749283e-09 1 0.662303696177438 3.97639370242915 -3.24784929097796 9.42005296034754e-09 369.397190140357 89.3217902620129 4.13557754559982 4.10392623804245e-05 -229.600835516318 165.749231341238 -1.38523016763574 0.166552980118055 NECTIN1 other 7.29771502838124e-05 1 0.351378164501195 4.13557754559982 -1.38523016763574 1.11657925031251e-18 399.426947157241 49.4771891748685 8.07295147154653 4.50168570849361e-15 -711.264241841939 219.189542369908 -3.24497343327446 0.00124748102628311 HIPK3 other 1.28105137388354e-14 1 5.76260787544267e-11 8.07295147154653 -3.24497343327446 0.00514107016781466 61.0859069624884 20.8308670544539 2.93247068414407 0.00350569068858074 179.199433822481 90.8670283401491 1.97210624244991 0.0491082880757455 KIAA1549L other 1 1 1 2.93247068414407 1.97210624244991 1.5164668692344e-35 171.821655955623 14.7728628619445 11.6308976507352 4.6513524816258e-28 -308.105093236143 64.4399797225787 -4.78127234928642 2.24945935829508e-06 FBXO3 other 2.17233879017828e-31 0.0281092441412554 6.77888110672144e-24 11.6308976507352 -4.78127234928642 2.05930691463644e-23 217.035804066737 22.6003277055085 9.6032149132881 3.0138623157172e-20 -170.226993053061 70.0552429006393 -2.42989655027671 0.015432294455499 PDHX other 2.59616822728216e-19 1 4.15430781598459e-16 9.6032149132881 -2.42989655027671 0.158302780802955 28.7493332426457 54.5079212688277 0.527434042124938 0.598113339270959 -240.956061805175 151.076187197986 -1.594930784753 0.111324946643069 SLC1A2 other 1 1 1 0.527434042124938 -1.594930784753 6.68472389692442e-19 126.772304326192 19.2491000305724 6.58588215162502 1.09791925648148e-10 -222.431481583874 51.7638666036649 -4.2970414727119 2.06251925960314e-05 COMMD9 other 7.70414429120539e-15 0.2442641559148 1.26337568843324e-06 6.58588215162502 -4.2970414727119 0.0652313777380816 73.4794376494453 37.6910023486803 1.94952198324909 0.0517713174961748 -38.9208301765022 94.3745437702603 -0.412408141238264 0.680210592225601 SLC15A3 other 1 1 1 1.94952198324909 -0.412408141238264 0.880907552541063 -3.94048473822612 10.1102425524855 -0.389751751035627 0.696879398301736 -11.6748460662925 26.022171562316 -0.448649953687931 0.653870728910133 CD5 other 1 1 1 -0.389751751035627 -0.448649953687931 4.37334689158945e-05 9.31481733114414 12.4784490518791 0.746472361462376 0.455713104551775 -128.925144499129 32.8571647301774 -3.92380613354382 9.86384277359211e-05 ACCS other 0.249674374040842 1 1 0.746472361462376 -3.92380613354382 0.0775490000116261 -7663.1659947387 4966.33821616857 -1.5430213693039 0.123431575944148 -26132.4630447603 12260.9629006418 -2.13135487453373 0.0335264110538968 SCGB2A2 other 1 1 1 -1.5430213693039 -2.13135487453373 3.61137161084153e-07 1764.87416302813 326.241406091135 5.40971847863823 9.60010351450739e-08 672.153746369409 924.847430896602 0.72677257233421 0.467688594288206 MDK other 0.0025066530350851 1 0.000981706585393525 5.40971847863823 0.72677257233421 3.3707910136886e-24 121.229137023315 21.3903249102668 5.66747525022999 2.37971237720298e-08 -421.216889390195 61.6703207826577 -6.83013942597565 2.32916983238692e-11 AMBRA1 other 4.30348888717623e-20 3.36401998891643e-07 0.000250845481680966 5.66747525022999 -6.83013942597565 3.33702980063413e-17 252.904734690822 44.0388480915335 5.74276452838109 1.55749913314154e-08 -584.732983389058 124.637332392309 -4.69147543649722 3.4427510475564e-06 MADD other 3.68808533566084e-13 0.0426212579687482 0.000165421982930963 5.74276452838109 -4.69147543649722 1.7149028185863e-28 230.552113661674 27.4444994653752 8.40066746170924 3.95636455718753e-16 -412.26131153273 77.8541557511772 -5.29530257640096 1.73315018226356e-07 PTPMT1 essential 2.31288943142735e-24 0.002268693588583 5.16068192839541e-12 8.40066746170924 -5.29530257640096 3.95506971480885e-14 87.743711769757 22.8739840174402 3.83596105089769 0.000140131083710753 -257.046741568548 52.6200521503692 -4.88495794025442 1.37217440525519e-06 NAA40 other 3.94953261720811e-10 0.0173168409943205 1 3.83596105089769 -4.88495794025442 2.03278002713503e-17 215.147175268619 30.5231375479361 7.04865857681681 5.55212983266242e-12 -139.465403417428 63.5584189051319 -2.19428685955193 0.0286408041057905 CARS other 2.25821533214431e-13 1 6.63257429809853e-08 7.04865857681681 -2.19428685955193 3.96731277778427e-12 64.1277051708828 37.6819523392304 1.70181482619519 0.0893614419532472 -424.12519716035 75.5609535640217 -5.61302070918143 3.17188943019794e-08 SLC22A18 other 3.66103623133933e-08 0.000426555690573019 1 1.70181482619519 -5.61302070918143 3.15154237266452e-09 1000.5298689935 347.314533346252 2.88076015522228 0.00412304670071511 -2523.41407227581 693.58776553237 -3.6382044172001 0.000300594505002375 CD81 other 2.51209442525089e-05 1 1 2.88076015522228 -3.6382044172001 1.22315330968758e-11 125.400133916675 29.9296771055222 4.18982581985619 3.26173480585873e-05 -137.691553843983 57.2372677363292 -2.40562764942374 0.0164805321516798 SLC35F2 other 1.10316197000723e-07 1 0.282074826010663 4.18982581985619 -2.40562764942374 0.583978624240864 0.931791786750493 1.51774650921909 0.613931101860953 0.539516556277452 -1.35086959371877 3.03094258633961 -0.445692900884072 0.655995762361677 C11orf21 other 1 1 1 0.613931101860953 -0.445692900884072 1.38149653685184e-32 537.041303127795 70.964116976586 7.56778673516064 1.66651816364557e-13 -1122.4773229035 165.385077231924 -6.78705323170982 3.0409717605812e-11 C11orf58 other 1.93616739639785e-28 4.38447308440597e-07 2.06481600475686e-09 7.56778673516064 -6.78705323170982 4.76910323801942e-11 125.921610798545 18.4764895660993 6.81523459031887 2.70075164463535e-11 -8.81465455565947 76.2746368799771 -0.115564687243675 0.908043670876858 PITPNM1 other 4.17964207780022e-07 1 3.16339040136139e-07 6.81523459031887 -0.115564687243675 4.06673126050161e-11 352.221752951389 200.194233710371 1.75940009071871 0.079073735162441 -2874.46588580955 502.16776258683 -5.72411472811842 1.7229733549195e-08 RPS13 essential 3.58075687487167e-07 0.000233721335594831 1 1.75940009071871 -5.72411472811842 6.80802603738076e-26 289.451956446941 26.1298497032994 11.0774443685527 1.15529900470169e-25 4.51185006086359 107.857089512774 0.0418317431078949 0.966649462142014 AIP other 8.91374849074263e-22 1 1.6606267893582e-21 11.0774443685527 0.0418317431078949 1.8282742054451e-20 421.898279574174 70.7912119180788 5.95975500549989 4.54803582408099e-09 -769.652764436676 154.540776332702 -4.9802568791277 8.54489923699095e-07 NUP98 essential 2.1844220206658e-16 0.0108870561178502 4.9305256368862e-05 5.95975500549989 -4.9802568791277 3.04983071015559e-08 329.346444450146 60.3915292807801 5.4535205246899 7.78226746713524e-08 -248.811643673321 234.26092031506 -1.06211331936497 0.288697995574915 TCIRG1 other 0.00022913378125399 1 0.000800484031669531 5.4535205246899 -1.06211331936497 2.32123521474246e-16 196.252971314677 24.8697433389665 7.89123428576696 1.88965411562049e-14 -187.659980745971 97.4323759762163 -1.92605362299468 0.0546620391149115 CHKA other 2.50322005557827e-12 1 2.39041245625992e-10 7.89123428576696 -1.92605362299468 1.56409456180866e-19 99.7262931884567 17.4174924825176 5.7256400878918 1.70997534685638e-08 -102.598486382439 33.2150244424401 -3.08891798530021 0.00211203576509246 EXPH5 other 1.83468292100156e-15 1 0.000181325785780651 5.7256400878918 -3.08891798530021 1.74263698618905e-11 114.947673686578 19.5827500397543 5.86984327804964 7.56072977633458e-09 -88.9002619308575 48.9283534463715 -1.81694775460404 0.0697712051371893 HPS5 other 1.56000863003644e-07 1 8.13458916635838e-05 5.86984327804964 -1.81694775460404 1.36378465175014e-30 161.851392033305 18.9618613435636 8.53562786378269 1.37951189637361e-16 -261.029328117276 47.3788905260713 -5.50940144901956 5.55034344552244e-08 GTF2H1 essential 1.87643130234301e-26 0.000740915346542791 1.81309248540383e-12 8.53562786378269 -5.50940144901956 0.176193423097278 24.4873011353819 16.41699856334 1.4915820965023 0.136387310830444 -2.46774663683992 30.2560776533313 -0.0815620142542904 0.935024952596202 POU2AF1 og 1 1 1 1.4915820965023 -0.0815620142542904 0.144448282983252 -326.94949608729 185.906439779174 -1.75867762556074 0.079193466102394 -876.217397635845 691.000836484099 -1.26804100859581 0.205324737157655 VWF other 1 1 1 -1.75867762556074 -1.26804100859581 9.95762526102581e-19 128.184384947761 25.8762351435345 4.95374942439373 9.73781274008036e-07 -351.247876535524 57.0776467216465 -6.15386051650785 1.46957667930437e-09 PSMD9 other 1.14363326122881e-14 2.05094121363717e-05 0.00937264476232734 4.95374942439373 -6.15386051650785 0.00863467661722347 56.8315286824066 40.3956754000981 1.40687160493097 0.160049371683421 -356.455878850038 151.356133074231 -2.35508050853293 0.0188809052461019 P3H3 other 1 1 1 1.40687160493097 -2.35508050853293 2.83529671688436e-12 262.155694829726 37.3820126322456 7.01288337277999 7.04926738575634e-12 -297.074227850421 208.91492676341 -1.42198660695436 0.155610678400594 PPFIBP1 other 2.63399064998557e-08 1 8.39708730991295e-08 7.01288337277999 -1.42198660695436 1.77431591993639e-08 68.835925169534 17.4179511303531 3.95201046635033 8.78344361138968e-05 -168.500227367262 50.4326482736949 -3.3410941748056 0.000892422773813445 PRPF40B other 0.000135256102576751 1 0.729464991925913 3.95201046635033 -3.3410941748056 0.438108900079707 1.87403290502418 6.80390507055538 0.275434898869217 0.783086914772831 -24.4127829900059 22.084338414758 -1.10543420099431 0.269461035533133 CD69 other 1 1 1 0.275434898869217 -1.10543420099431 5.36210770622753e-15 137.006636664765 26.69301248139 5.13267795308918 3.97774233837098e-07 -292.610997205098 61.7666978736465 -4.73735859740599 2.76436934471653e-06 PRDM4 other 5.53369515282681e-11 0.0344081052336866 0.00392802055914134 5.13267795308918 -4.73735859740599 0.874261636899049 -1.9250009227145 7.64677795240598 -0.251740136132607 0.801337178824349 8.77407110606079 24.9766732315977 0.351290623242844 0.725506591085476 CLEC2B other 1 1 1 -0.251740136132607 0.351290623242844 1.5457626073787e-31 127.767236841876 16.3043983316658 7.83636625178201 2.45327849226715e-14 -262.383852278472 36.4729176637355 -7.19393646259773 2.09629744469733e-12 COQ5 other 2.1453639227809e-27 3.07023723750371e-08 3.09677344078882e-10 7.83636625178201 -7.19393646259773 0.179474762369356 -44.6058334566776 26.8207235089889 -1.66311074500761 0.0968630787342364 -79.7682242706143 61.7002349064759 -1.29283501742782 0.196613914642108 SELPLG other 1 1 1 -1.66311074500761 -1.29283501742782 4.62545718613593e-05 351.365987341701 87.0705997970136 4.03541480316932 6.22875221623501e-05 632.404242694936 201.045631695054 3.14557564550403 0.00174787601775984 CORO1C other 0.263234768462996 1 0.524834661739962 4.03541480316932 3.14557564550403 0.256239675068444 13.8039328529552 10.4617630096499 1.31946526032205 0.187570708566462 40.1387665688907 30.4355046118278 1.31881390109405 0.187788281711882 ASIC1 other 1 1 1 1.31946526032205 1.31881390109405 1.85896213158532e-19 74.715181202051 8.16392255664101 9.15187285078707 1.18669057355981e-18 -52.0123215310601 38.6643858615712 -1.34522559642556 0.179124441225141 CAPRIN2 other 2.17684465608641e-15 1 1.60772838905883e-14 9.15187285078707 -1.34522559642556 0.582795117357454 -5.1396552362481 5.99115702886538 -0.857873564569457 0.391348594205147 -21.682588191653 29.1960549080221 -0.742654727152722 0.458018532096898 TSPAN11 other 1 1 1 -0.857873564569457 -0.742654727152722 3.33377931427844e-09 163.462642190385 38.8009041047784 4.21285652903778 2.95236568648055e-05 -288.946084676054 88.593933829372 -3.26146579327374 0.00117793913501625 KCTD10 essential 2.65502184589135e-05 1 0.256324388900241 4.21285652903778 -3.26146579327374 3.75892436849217e-05 231.060808312386 53.6456038947845 4.30717135304445 1.96334943171626e-05 -42.1785977573327 157.682121840899 -0.267491312679638 0.789192658130718 SLC11A2 other 0.215950204969875 1 0.172696216013762 4.30717135304445 -0.267491312679638 1.15841413909912e-10 548.533423539815 205.906379127213 2.66399431559583 0.00795131765354476 -2416.55520737572 458.140996013817 -5.27469758961025 1.92377508236994e-07 MLEC other 9.95541111141781e-07 0.00251264263508338 1 2.66399431559583 -5.27469758961025 1.06609478573946e-12 87.3849481202451 18.3807186940589 4.75416383737433 2.55935723855656e-06 -177.212917907666 41.9630143657848 -4.22307407096474 2.82812358359851e-05 MVK essential 1.00639347773805e-08 0.331512646469417 0.0240353264078186 4.75416383737433 -4.22307407096474 1.34202683723637e-10 104.085187521941 37.9894313052569 2.73984589781259 0.006349358941229 -594.190272289913 112.151973691373 -5.29808127964866 1.70481864926406e-07 CSRNP2 other 1.1502512021953e-06 0.00223246002121129 1 2.73984589781259 -5.29808127964866 5.86174621253681e-11 111.585863060429 37.0361219985108 3.01289273928075 0.00270836708651721 -417.606066268054 81.7894105405244 -5.1058696169615 4.56338894637166e-07 CAMKK2 other 5.11495974505962e-07 0.00588129567408379 1 3.01289273928075 -5.1058696169615 0.0196747293088856 -8.28640020207412 10.0523891130563 -0.824321473122398 0.410119525218934 68.3883292464637 29.1307051414266 2.34763727532325 0.0192516011918894 BIN2 other 1 1 1 -0.824321473122398 2.34763727532325 0.204867279683664 0.777332611441959 2.55953471501464 0.303700749547174 0.761473083811511 13.4409601155026 7.56902018287562 1.7757860054214 0.0763323219865914 IL23A other 1 1 1 0.303700749547174 1.7757860054214 1.44891139666968e-11 2013.29379400026 289.974776087615 6.94299628803557 1.10798453251261e-11 -132.670431514588 857.498559240529 -0.154717964345143 0.877101583879203 ATP5B essential 1.30271623674571e-07 1 1.3130724694807e-07 6.94299628803557 -0.154717964345143 2.50041635509724e-19 1305.69985451714 145.148313143181 8.99562541404903 3.99358528459487e-18 -454.534703662831 431.17728947585 -1.05417125335004 0.292276830469033 PTGES3 other 2.91898605294052e-15 1 5.37616451012162e-14 8.99562541404903 -1.05417125335004 1.15622849654299e-06 97.6680270974468 24.9054553387994 3.92155155442162 9.92511998513964e-05 -119.915429679527 54.9363063592705 -2.18280837621861 0.0294775220077297 BCL7A other 0.00767157607456275 1 0.820608920371346 3.92155155442162 -2.18280837621861 9.88548197817301e-14 128.667660697507 33.431737211523 3.84866810490358 0.000132940715575804 -407.564320548535 73.7946196339098 -5.5229544182277 5.18372683734585e-08 RSRC2 essential 9.72632571832443e-10 0.000692494068201032 1 3.84866810490358 -5.5229544182277 0.0183986605687662 27.3300536900435 9.65940939477445 2.82937109020646 0.0048434594458336 25.2545748898388 27.5749491517212 0.915852092813829 0.36016737002333 CYP27B1 other 1 1 1 2.82937109020646 0.915852092813829 0.000607916080198749 -62.3682503789436 51.6811743251302 -1.20678856843655 0.228049904820257 -664.54719195697 172.302021560973 -3.85687402815413 0.000128916929079688 LIN7A other 1 1 1 -1.20678856843655 -3.85687402815413 6.77792211393832e-16 3646.87034056006 768.253559053972 4.74696185599299 2.64599441430244e-06 -12944.3273662584 2278.72762609758 -5.68050662045387 2.19339194210513e-08 KRT18 other 7.20560899932782e-12 0.000296524656653192 0.024811489622914 4.74696185599299 -5.68050662045387 3.43804187083068e-06 80.2870012188257 41.6954548360024 1.9255576305526 0.0546933089700058 -449.735707922141 111.254227789398 -4.04241453882978 6.07346072626035e-05 ACSS3 other 0.0218246897960332 0.696140068443961 1 1.9255576305526 -4.04241453882978 1.11626605143038e-07 24.5272514532384 76.9772076578874 0.318630049069145 0.750130952946152 -1234.76559281913 227.001675999978 -5.43945584269278 8.13089047145862e-08 TNS2 other 0.000804604569871016 0.0010797822546097 1 0.318630049069145 -5.43945584269278 0.055893498100893 -5.38013355063391 2.88022468556475 -1.86795619716695 0.0623314747681537 -15.6112612978102 8.15722539326702 -1.91379550584636 0.0561960204251955 GLI1 og 1 1 1 -1.86795619716695 -1.91379550584636 0.0169403216349779 210.2514636025 82.0799910537253 2.56154345173942 0.0106963645209484 -157.348748056687 246.781611880369 -0.637603210619128 0.52400735322181 PPM1H other 1 1 1 2.56154345173942 -0.637603210619128 4.26195764689676e-23 342.729616933825 36.2849972250287 9.44549106090095 1.04173995618274e-19 -224.864890264849 99.2119823170485 -2.26650939748644 0.0238128051049398 METAP2 essential 5.34875684685543e-19 1 1.42780878394406e-15 9.44549106090095 -2.26650939748644 5.18621282803639e-13 141.435804111444 46.3391141784354 3.05219050081159 0.0023829408437051 -770.478397969488 127.041004283796 -6.06480090670824 2.47693693139059e-09 LTA4H other 4.95075876564354e-09 3.43947462292898e-05 1 3.05219050081159 -6.06480090670824 0.0108658602195449 -23.6972800110957 38.9210140832266 -0.60885566754306 0.542874737707783 -320.240227329415 106.213713556613 -3.01505536908588 0.00268944956025878 ELK3 other 1 1 1 -0.60885566754306 -3.01505536908588 0.629895172905903 -1.1161041144675 9.04633538320033 -0.123376380289878 0.901857100885503 -32.8567497682145 34.5634377448005 -0.950621579103696 0.342241548403256 SLC6A12 other 1 1 1 -0.123376380289878 -0.950621579103696 0.0416513502131385 19.908174496922 9.31871099647839 2.13636569526037 0.0331052905352681 -29.68841202841 37.2175037684788 -0.797700249138 0.425400360931148 WNT5B other 1 1 1 2.13636569526037 -0.797700249138 1.59232294555925e-71 220.801896671416 10.7762830953596 20.4896154562325 1.228663333659e-69 33.4801801979906 38.7638975141401 0.863694889962443 0.388134767519226 MAGOHB other 2.46634901037673e-67 1 1.90627116217193e-65 20.4896154562325 0.863694889962443 0.319085452887731 15.9206011273183 16.6178037260694 0.958044840928205 0.338471270932384 52.4641695532392 37.2657048892398 1.40784052546898 0.159756908925475 TRPV4 other 1 1 1 0.958044840928205 1.40784052546898 8.47481780308585e-33 941.458379839763 72.2861715737732 13.0240453926784 6.83611697739823e-34 784.331038884308 265.972032013193 2.9489229861785 0.00332771650909149 FOXM1 other 1.19011866408735e-28 1 1.01837634612301e-29 13.0240453926784 2.9489229861785 0.183106244578074 19.203326535488 179.352311477431 0.107070415637796 0.914772591099649 1183.21586816824 662.918145514599 1.78485967864065 0.074841188240006 PRR4 other 1 1 1 0.107070415637796 1.78485967864065 1.88338841744501e-07 8.30694016611631 8.68149617583787 0.956855822759675 0.339065843195347 -165.418334193164 32.0937694756939 -5.15421955399918 3.57195141663898e-07 PARP11 other 0.00133607574333549 0.00462103354770584 1 0.956855822759675 -5.15421955399918 4.20199722788796e-19 546.79320430185 82.941489347612 6.59251731072987 1.03066450935664e-10 -848.635204622729 186.220886342101 -4.55714297838603 6.41783902351214e-06 ARPC3 essential 4.87347638490445e-15 0.0783810679941538 1.1869132489751e-06 6.59251731072987 -4.55714297838603 2.00979567478715e-26 92.2129581369467 10.5037100998237 8.77908446259329 2.17467126665323e-17 -102.545656557194 23.5830127967912 -4.34828482012894 1.64040511296751e-05 GPN3 essential 2.64730286282963e-22 0.195651117823635 2.8966621271821e-13 8.77908446259329 -4.34828482012894 2.46107117077147e-31 232.908962657676 25.4639580507112 9.14661272194371 1.18800183134895e-18 -314.817053903562 56.9610010187127 -5.52688766477504 5.0749691816799e-08 VPS29 essential 3.41104464268925e-27 0.000678117382056069 1.60938608092842e-14 9.14661272194371 -5.52688766477504 0.120539879816992 127.871984303781 640.972258219383 0.199496909053457 0.841949437666387 2880.57869911071 1430.23003863586 2.01406670346414 0.0444997827984054 MYL2 other 1 1 1 0.199496909053457 2.01406670346414 6.40061772435838e-45 191.152169439552 12.2258541512234 15.6350768686721 8.83006182815329e-46 119.19243060234 44.0870796647103 2.70356829050186 0.00707452367801441 RAD51AP1 other 9.55548220069462e-41 1 1.34658442879338e-41 15.6350768686721 2.70356829050186 0.42632098616949 9.15299196632112 13.2275223466823 0.69196571560636 0.489258491553543 -24.9653634558779 29.7265094618022 -0.839835012851333 0.401375336826345 CUX2 other 1 1 1 0.69196571560636 -0.839835012851333 0.152496130109927 -49.8319890585897 26.773840187651 -1.86121933608814 0.0632594259560013 -66.4948337481995 60.1665175393977 -1.10518003147944 0.269576499291557 SH2B3 other 1 1 1 -1.86121933608814 -1.10518003147944 4.54380452929109e-17 20.0173502994445 2.27846280731714 8.78546282834199 2.03363044682354e-17 4.44236661339269 8.21625794458041 0.540680032608148 0.588949447129707 AKAP3 other 5.00272878674949e-13 1 2.71021929648173e-13 8.78546282834199 0.540680032608148 1.04250782018313e-11 199.102941018007 43.4239612492347 4.58509392718096 5.64219141925184e-06 -553.911134300207 142.448507812597 -3.88850078393888 0.000113408125023064 MANSC1 other 9.43886580393808e-08 1 0.0517614640802164 4.58509392718096 -3.88850078393888 0.721459580635634 -0.140365135879195 1.61925202336963 -0.0866851693580706 0.930953779488992 4.34620153711772 5.78429549803052 0.75137958262982 0.452750368652034 KCNA1 other 1 1 1 -0.0866851693580706 0.75137958262982 4.32550445811561e-13 240.491308298259 75.1485961787453 3.20021025710496 0.00145381004397599 -1386.04374085405 246.833183103013 -5.61530554129587 3.1403666395114e-08 DUSP16 other 4.1416705186457e-09 0.000422442120347073 1 3.20021025710496 -5.61530554129587 1.47152336218511e-14 36.5503357587704 37.6370887593493 0.971125476587003 0.331920577025172 -886.159096896849 119.879499744877 -7.39208203890355 5.53925388942433e-13 CREBL2 other 1.49344906028166e-10 8.15932097912204e-09 1 0.971125476587003 -7.39208203890355 2.00664744339437e-20 115.481824993424 19.073993845376 6.05441240725888 2.64901774308675e-09 -239.056204951023 42.0798356715489 -5.68101564884803 2.19687869381138e-08 ACAD10 other 2.3955357179242e-16 0.000296974061829422 2.89749560738828e-05 6.05441240725888 -5.68101564884803 0.0202758321076269 576.566175113925 250.93808775829 2.29764313685728 0.0219650045717808 -470.337424520866 562.28876163894 -0.836469544847282 0.403262171701573 ALDH2 other 1 1 1 2.29764313685728 -0.836469544847282 3.39938642580571e-12 154.592768227621 69.8916846226053 2.2118907143586 0.027391317450358 -1338.01103104625 223.43722102706 -5.98830859467327 3.86711466420095e-09 CDKN1B ts 3.14749189165351e-08 5.34435246592571e-05 1 2.2118907143586 -5.98830859467327 1.09325961600103e-11 158.727900497652 23.4368923031789 6.77256602301843 3.32380378232773e-11 -25.0027714940465 52.1264532780084 -0.479656103988086 0.631666874308725 NAA25 essential 9.88634670749734e-08 1 3.88253519813702e-07 6.77256602301843 -0.479656103988086 4.87362234244502e-10 -333.08488758227 104.10523965088 -3.19950166484684 0.0014574730844133 -2529.48534485134 392.630524839709 -6.44240624409936 2.60536862567633e-10 SCNN1A other 4.06070213572519e-06 3.69623646924701e-06 1 -3.19950166484684 -6.44240624409936 3.40430334983635e-35 581.241403653367 46.7703150602908 12.4275708406945 2.3088325599873e-31 -438.711843063108 176.393171089399 -2.4871248719757 0.0131788504257359 LTBR other 4.86304733524123e-31 1 3.41106922412524e-27 12.4275708406945 -2.4871248719757 1.05103053766948e-12 70.8641703321267 13.8783627861087 5.10609006438836 4.61087302181463e-07 -115.355199603583 29.8844083021875 -3.86004629695611 0.000127521420091907 OGFOD2 other 9.92383033667523e-09 1 0.00453433252965251 5.10609006438836 -3.86004629695611 0.00469898079826753 483.270764566656 187.020612846176 2.58405080173779 0.0100233082038781 1139.88070154489 422.99385913763 2.69479255294344 0.00726018749191429 CDK2AP1 other 1 1 1 2.58405080173779 2.69479255294344 0.00142953186358377 892.359447598303 245.776855059237 3.63077087703489 0.00030937690821309 737.938433979893 545.694450272634 1.35229235630161 0.176845755575216 OAS3 other 1 1 1 3.63077087703489 1.35229235630161 0.022878481507004 673.420850961255 256.176473572694 2.6287380787532 0.00881337996896206 900.553450132475 568.784558193408 1.58329447795285 0.113937657726951 OAS2 other 1 1 1 2.6287380787532 1.58329447795285 0.146380407678413 36.0898046038633 19.2777477532202 1.87209652630893 0.061736533551494 1.83444861409402 61.0021433699327 0.030071871458179 0.976020906680755 ART4 other 1 1 1 1.87209652630893 0.030071871458179 0.206157886688602 -2100.96717963229 3751.92838487003 -0.559969957876759 0.575733436291111 -21130.1582178094 11872.5318007821 -1.77975166311346 0.0756820359353717 MGP other 1 1 1 -0.559969957876759 -1.77975166311346 4.67778095234082e-05 12.8511845707562 14.4730279255636 0.887940287053356 0.374968195873949 142.164483119449 31.738100427485 4.47930031112811 9.14498074572226e-06 RASAL1 other 0.265885069331052 0.110672556984731 1 0.887940287053356 4.47930031112811 0.00896751147159984 -118.37584500164 351.547982837117 -0.336727419245319 0.736453943734587 -3380.50965599216 1119.5059154648 -3.01964429959143 0.00265105453313945 ARHGDIB other 1 1 1 -0.336727419245319 -3.01964429959143 5.44568052933484e-19 143.451088466611 18.1153304072553 7.91876743297809 1.3535552514532e-14 -117.199719845984 41.5327126146417 -2.82186528323861 0.00494875428091196 GTF2H3 essential 6.29575125996401e-15 1 1.71820303619469e-10 7.91876743297809 -2.82186528323861 2.61029962836201e-30 209.514578184675 22.4721005949935 9.32331970031105 2.7943586256205e-19 -268.938656137351 51.5214061723866 -5.21994013978389 2.54919091917241e-07 EIF2B1 essential 3.58054800022418e-26 0.00331524726820118 3.81262290879661e-15 9.32331970031105 -5.21994013978389 4.90446079698749e-19 125.58374631694 14.6390668096946 8.5786715744595 9.96517720092208e-17 -52.1924809039759 33.5680300183703 -1.55482704452461 0.120566686123119 DDX55 essential 5.67593248035362e-15 1 1.31390861394158e-12 8.5786715744595 -1.55482704452461 6.39311410611594e-06 928.379473977919 460.239305592253 2.01716685797456 0.0441817450070459 -5341.68556299433 1375.18011500734 -3.88435340556522 0.000115582240975555 SLC38A1 other 0.0394774796052659 1 1 2.01716685797456 -3.88435340556522 0.376493092047766 2.24922885056319 5.54708714804314 0.405479270567555 0.685288573856828 -20.039754336775 17.6110859384946 -1.13790565821792 0.25567304121663 RERGL other 1 1 1 0.405479270567555 -1.13790565821792 0.00337112471340971 194.972207081061 57.6456947264041 3.38225097305933 0.000770943672754051 101.877163900231 126.654630443851 0.8043698326955 0.421536738577451 C12orf49 other 1 1 1 3.38225097305933 0.8043698326955 0.153659093543703 14.1362562305005 34.838124901363 0.405769721261532 0.685074038406017 -171.250932729649 99.6699971327736 -1.71817936847655 0.0863424837430994 VDR other 1 1 1 0.405769721261532 -1.71817936847655 0.259957906441543 -9.15092509392493 7.79235837450319 -1.1743460264696 0.240771216878252 -26.6148845905755 18.3010600508932 -1.45428103708542 0.146446167129383 FZD10 other 1 1 1 -1.1743460264696 -1.45428103708542 5.38904175237178e-12 118.65563046388 17.5363881172483 6.76625252991368 3.44270635813771e-11 -30.6212644235815 39.242611742707 -0.78030648480659 0.435551759752054 RFC5 essential 4.94983484955348e-08 1 4.01901540248996e-07 6.76625252991368 -0.78030648480659 0.00823912209407854 20.6084729101289 8.06477026387965 2.55537011419033 0.0108788724481119 -17.3724032026802 18.8708733482166 -0.920593492527569 0.357671501771652 STX2 other 1 1 1 2.55537011419033 -0.920593492527569 0.613108974116089 -11.1983706698939 11.8322705993896 -0.946426180489107 0.344352998334416 -0.537068729201836 27.7175873634782 -0.0193764602293452 0.984547919666783 ADGRD1 other 1 1 1 -0.946426180489107 -0.0193764602293452 1.35262425532293e-35 690.611561367516 84.6989803455711 8.15371753650194 2.48071841203992e-15 -2258.42757714065 267.094960462975 -8.45552298413253 2.60498975530179e-16 COPZ1 essential 1.9380400330267e-31 3.94603848133115e-12 3.18995580604213e-11 8.15371753650194 -8.45552298413253 5.2267988587996e-18 107.861356057243 15.559775632303 6.93206371390836 1.22387497777622e-11 -339.698494500518 67.9804018812741 -4.99700627092191 7.94888461881099e-07 TBC1D30 other 5.90001055181299e-14 0.0101419818851409 1.44901125060245e-07 6.93206371390836 -4.99700627092191 1.60221909284147e-11 639.177797786619 88.5514115371731 7.21815481753555 1.85769686668001e-12 284.519149151481 374.447854507811 0.759836505207017 0.447693380018758 CAND1 other 1.43638941673238e-07 1 2.24595551181613e-08 7.21815481753555 0.759836505207017 9.66595110030623e-33 493.242808478807 86.6257827936813 5.69394922125639 2.04184033484166e-08 -2477.94358599836 254.423199907848 -9.73945609872004 9.34276947922415e-21 RAB5B other 1.35622959888397e-28 1.44252360759221e-16 0.000215802104989415 5.69394922125639 -9.73945609872004 1.56192996312096e-20 54.1700176038053 6.32519577730649 8.56416457466127 1.21270135310033e-16 -115.366719255227 28.4918316302244 -4.04911557643929 5.91644674572262e-05 MDM1 other 1.86884920087422e-16 0.678616441734384 1.59579371054473e-12 8.56416457466127 -4.04911557643929 3.16365908676448e-37 293.317932383982 20.8767618967973 14.0499725883725 2.91063595822098e-38 261.741869361101 102.586023895766 2.55143789983564 0.0110119349168214 NUP107 essential 4.57180374628336e-33 1 4.38254456229334e-34 14.0499725883725 2.55143789983564 2.93032954432295e-138 468.480157392948 13.631698042127 34.3669699802015 4.27388409219674e-137 -279.958367518955 99.7367143249741 -2.80697403572731 0.0051846841373735 CNOT2 other 4.58860303345531e-134 1 6.69204771156166e-133 34.3669699802015 -2.80697403572731 3.26157884963172e-11 356.414777782163 50.2900804271019 7.08717852020151 4.30694808808939e-12 353.569381189192 149.683397573417 2.36211488328739 0.0185254805550427 TIMELESS essential 2.88388801884437e-07 1 5.1605851991487e-08 7.08717852020151 2.36211488328739 2.51436226480152e-33 245.988820963877 18.6603714069996 13.1824182701747 1.8583739737108e-34 198.254109861776 112.265229530752 1.76594401214375 0.0779897370335 CPSF6 essential 3.54399361223774e-29 1 2.77287980617389e-30 13.1824182701747 1.76594401214375 2.92882136146093e-15 297.929553562795 38.9605306329357 7.64695831198298 9.80035688670342e-14 -231.130205456988 122.356240394336 -1.88899401217371 0.0594403789380132 KRR1 essential 3.04919591941697e-11 1 1.22024243596344e-09 7.64695831198298 -1.88899401217371 1.12377808523205e-54 695.838168161775 42.4453360092472 16.3937486090387 2.47312388655516e-49 -458.335681368872 160.198432350222 -2.86104972841974 0.00438568736694398 MRPL51 other 1.71263780189365e-50 1 3.78783654464788e-45 16.3937486090387 -2.86104972841974 1.70554726467273e-32 20748.4868566254 1630.0671949563 12.7286083180035 1.68754513176283e-32 1899.61712765493 6174.26782877773 0.30766678419763 0.758459084920497 GAPDH essential 2.38827783472122e-28 1 2.50279818491745e-28 12.7286083180035 0.30766678419763 1.67577924217248e-56 565.439999351105 31.6009141390824 17.893153244317 3.78416557263961e-56 77.2393831959837 119.39330605726 0.646932275741997 0.517961232857064 NOP2 essential 2.56293677297859e-52 1 5.83139914743764e-52 17.893153244317 0.646932275741997 7.18569321166155e-09 625.068582133372 114.723063998153 5.44849972053948 7.82123992579184e-08 -719.582952345281 426.775933371954 -1.68609074710437 0.0923724612707999 CHD4 essential 5.61202639830767e-05 1 0.000804258101569175 5.44849972053948 -1.68609074710437 0.000635090164468945 3.09323645637227 1.33422735741196 2.3183728314283 0.020808703156173 -12.4144795829135 4.99190344527275 -2.48692301824664 0.0131919460746448 ACRBP other 1 1 1 2.3183728314283 -2.48692301824664 5.3916970248886e-10 40.3024614120732 24.9945023449586 1.61245304490738 0.107448716485866 -353.209264832656 61.6851353779668 -5.72600291250748 1.70962160223244e-08 UHRF1BP1L other 4.48265690649238e-06 0.000231944362774875 1 1.61245304490738 -5.72600291250748 4.25352741880568e-51 337.439312472456 24.3529934695789 13.8561738988669 1.76510640618839e-37 -586.234412925003 89.7260460074594 -6.5336035522647 1.50874945421559e-10 COPS7A other 6.4462208032e-47 2.14921359753011e-06 2.65295492850115e-33 13.8561738988669 -6.5336035522647 1.61944074715934e-32 193.322156394539 17.421959566358 11.0964645313405 7.18457925135772e-26 -264.70864154209 65.1828487098337 -4.0610167671631 5.62410611552355e-05 ING4 other 2.26835065454609e-28 0.646266033734811 1.03407649164792e-21 11.0964645313405 -4.0610167671631 7.58712902707577e-07 8.06699489062944 1.77527689561388 4.54407698909409 6.82381182846236e-06 -11.6239523068391 6.65148519046901 -1.74757245547132 0.0811107265356076 GNB3 other 0.00512586437069239 1 0.0622604591228906 4.54407698909409 -1.74757245547132 1.75929934941073e-44 220.326488076581 14.1018448253146 15.6239478455377 1.27767441672716e-45 155.252757811793 52.8358208489145 2.93839965609208 0.00344118175571686 CDCA3 other 2.62170789049187e-40 1 1.94781464830055e-41 15.6239478455377 2.93839965609208 7.06759919575089e-05 -68.7128620252428 127.474760023659 -0.539031114963384 0.590085501647735 -1340.45752620797 308.516505860887 -4.34484865718139 1.6627491838777e-05 CHPT1 other 0.391757023420472 0.198232957701899 1 -0.539031114963384 -4.34484865718139 6.65069148305806e-46 642.808080706283 45.4380583117848 14.1469091019579 7.93191392552531e-39 -661.174002257515 170.260106808975 -3.8833172059461 0.000115935650039893 USP5 essential 9.95675021928622e-42 1 1.19629125824773e-34 14.1469091019579 -3.8833172059461 2.58389408753937e-40 2937.2656121039 208.756129106484 14.0703203526333 1.75024767268161e-38 -87.4822096986187 729.007407255887 -0.120001811816861 0.904526762603832 TPI1 essential 3.79005584760275e-36 1 2.63762324273119e-34 14.0703203526333 -0.120001811816861 0.131441728932878 70.2311318615804 59.8239904625296 1.17396267481637 0.240922719835673 -177.904278779873 144.787003330927 -1.22873099578732 0.219702975600783 GNPTAB other 1 1 1 1.17396267481637 -1.22873099578732 4.44859589646878e-05 245.191052050962 66.4041464657399 3.69240574724447 0.000244898968616626 -329.780136079727 232.854224411797 -1.4162514633899 0.157282755322704 ENO2 other 0.25356996609872 1 1 3.69240574724447 -1.4162514633899 9.60410323786009e-32 845.947885123537 96.207800630094 8.79292406211522 1.97864770740688e-17 -2101.65239435599 332.807230617658 -6.31492407918999 5.67117257740148e-10 ATN1 other 1.33554659625682e-27 7.9895479270432e-06 2.63773525874411e-13 8.79292406211522 -6.31492407918999 5.86406026485002e-09 -1.25525168733556 70.8110972495787 -0.0177267650988564 0.98586337615557 -1469.62350243947 245.247575012687 -5.99240788563738 3.78082124924062e-09 C12orf57 other 4.60094168380132e-05 5.22622921282531e-05 1 -0.0177267650988564 -5.99240788563738 1.45949236171949e-15 122.900114252945 23.3610112303815 5.26090728868411 2.07030792843568e-07 -393.738591894624 80.9086651192839 -4.86645764472982 1.49343370785204e-06 PTPN6 other 1.53451026911187e-11 0.0188127844178121 0.0020775540061852 5.26090728868411 -4.86645764472982 1.68854494943172e-24 217.378185522514 34.2915617469972 6.33911593546913 4.86291060476691e-10 -902.585085236371 125.595513978275 -7.18644366065888 2.20861316059542e-12 LPCAT3 other 2.16606546113101e-20 3.23451397369199e-08 5.4785550873304e-06 6.33911593546913 -7.18644366065888 0.0183610538193839 46.4391345123319 16.4372571632768 2.82523623321315 0.00489742053156381 25.2760865411256 39.5598117250964 0.638933438732486 0.5231341687526 NT5DC3 other 1 1 1 2.82523623321315 0.638933438732486 4.33988896486554e-23 234.689427417061 43.2973927859568 5.42040553289807 8.95694868945235e-08 -690.188208232063 97.2053829669367 -7.10030851343719 3.91727363519435e-12 SUDS3 other 5.44612666200977e-19 5.71726087056615e-08 0.000917818532208183 5.42040553289807 -7.10030851343719 4.4840270038415e-39 421.397721156907 30.3217900713218 13.8975212270025 1.18211232632962e-37 35.4773907969576 107.041625664159 0.331435463324026 0.74044683812489 GOLT1B other 6.53950498240245e-35 1 1.77730588263658e-33 13.8975212270025 0.331435463324026 6.32674905498434e-32 3816.32412674012 297.646897185572 12.8216492858677 6.01783377367198e-33 3145.79809177922 1042.01920525997 3.01894444545711 0.00265939804780642 LDHB other 8.81316143359318e-28 1 8.93768672065763e-29 12.8216492858677 3.01894444545711 4.57472319931657e-23 37.5365843917678 20.4847169263734 1.83241899444755 0.0674344706546853 -434.669801190523 45.9506931515843 -9.45948301055251 9.18324456690916e-20 PRKAB1 other 5.73944772586257e-19 1.41339317129299e-15 1 1.83241899444755 -9.45948301055251 6.44454075103219e-57 402.549641887601 23.0094783466755 17.4949486391013 2.36466704352582e-54 -1.98858602992234 81.4370489604788 -0.024418689715628 0.980527901206584 CMAS other 9.86208071130457e-53 1 3.63945904669059e-50 17.4949486391013 -0.024418689715628 3.93024164089148e-06 19.4157610454426 10.3453701770751 1.87675846423234 0.0610832935670817 -95.2614202364744 24.7581394055376 -3.84768090509934 0.00013330095844487 HCFC2 other 0.0248116154789479 1 1 1.87675846423234 -3.84768090509934 9.83164091163666e-18 105.54596943036 11.5177453228405 9.16377003240857 1.13168486099295e-18 135.259289794386 41.0778093552778 3.29275810753545 0.00105903994545144 ST8SIA1 other 1.10222526260359e-13 1 1.53377249210374e-14 9.16377003240857 3.29275810753545 0.0247681043685661 2.72075163684815 4.21158961342056 0.646015373430085 0.518540816393804 41.2185230263285 15.104624333659 2.72886780338373 0.00656008970206567 CLEC4A other 1 1 1 0.646015373430085 2.72886780338373 3.16955941149344e-18 112.124970249261 25.0602738652817 4.47421168866786 9.41309728808756e-06 -587.695482022483 89.3769677462549 -6.57546901446664 1.17506106569557e-10 C2CD5 other 3.5971329761039e-14 1.6778696957067e-06 0.0850285078032949 4.47421168866786 -6.57546901446664 1.68717088028248e-17 190.707198377636 24.1260536157424 7.90461637095917 1.50328232777967e-14 -107.098821229648 54.3139336035407 -1.97184799781591 0.0491331568231832 RAB35 other 1.8778211897544e-13 1 1.90601166339184e-10 7.90461637095917 -1.97184799781591 3.14347271610354e-50 279.243350874845 20.5967257523998 13.557657378737 2.67635308908349e-36 -402.916238083965 69.4085784544559 -5.80499193407841 1.09256647976075e-08 PHC1 other 4.75638856673626e-46 0.000149102547492949 4.0134590923896e-32 13.557657378737 -5.80499193407841 1.50249087298958e-17 621.268835628867 88.129327737845 7.04951293259528 5.46746702030395e-12 -672.238170265712 198.10599841974 -3.39332567225651 0.000740778780050458 COX6A1 other 1.67542757247068e-13 1 6.53252959585916e-08 7.04951293259528 -3.39332567225651 2.59999852973723e-08 51.9726803520857 16.2490244195488 3.19851081579758 0.00146164115189637 -145.416140822155 37.9184721978935 -3.83496835165825 0.000140251296393534 RIC8B other 0.000196273889009863 1 1 3.19851081579758 -3.83496835165825 2.61922527810216e-32 614.069433486129 64.845662720325 9.46970711263403 8.49114631622326e-20 -802.817144052999 145.766626004605 -5.50755111823496 5.61878737346423e-08 SRSF9 other 3.65905771350871e-28 0.000749883362862536 1.16481545165951e-15 9.46970711263403 -5.50755111823496 1.60164873690886e-59 185.61569326468 10.4221204870713 17.8097819436012 3.85443786151091e-56 -153.368385888713 58.040745699739 -2.64242617905239 0.00847071687459131 FGFR1OP2 other 2.45885114090248e-55 1 5.93930330080216e-52 17.8097819436012 -2.64242617905239 0.490005258326582 -2.81161251980165 2.38122469404591 -1.18074221505929 0.238224950884886 -1.3526451152261 7.75656408312635 -0.174387151415231 0.861626570178816 KLRB1 other 1 1 1 -1.18074221505929 -0.174387151415231 0.148315056950607 -564.750935678433 983.017217881921 -0.57450767433686 0.565865791823889 -4118.11457282693 2165.07643894885 -1.9020642868509 0.0576995331925422 COL12A1 other 1 1 1 -0.57450767433686 -1.9020642868509 0.0225441197854644 58.247808196612 22.6145805393774 2.57567493216108 0.0102732437015667 -22.3015024401457 91.088869746781 -0.244832354404461 0.806680646270718 BTN3A3 other 1 1 1 2.57567493216108 -0.244832354404461 1.53624961290751e-21 146.954021177907 18.1727459066305 8.08650613027553 4.07681796928476e-15 -228.862773234523 63.3433885637968 -3.6130491030492 0.00033094045215886 TDP2 other 1.8751462775149e-17 1 5.22199613685685e-11 8.08650613027553 -3.6130491030492 9.06673145693413e-06 116.196216615072 37.1900879639761 3.12438671098666 0.00187816024442556 -254.02762857783 114.611636406767 -2.21642091974207 0.0270817740796056 FRK other 0.0553523955445829 1 1 3.12438671098666 -2.21642091974207 3.84477358753165e-07 97.0047911893737 27.0771826495579 3.58252896709538 0.00037116105012833 -208.186809157559 84.567815254674 -2.46177353087116 0.0141377822584012 DSE other 0.0026605833225719 1 1 3.58252896709538 -2.46177353087116 4.52797965391525e-52 189.24996118697 14.9458076204995 12.6624111585243 2.28908015201592e-32 -274.460247253356 47.0677671057687 -5.83117203407164 9.47316460080232e-09 RWDD1 other 6.87302031667796e-48 0.000129611838068177 3.3937902333788e-28 12.6624111585243 -5.83117203407164 0.0929632975227818 -0.270554930813986 1.95533662847102 -0.138367443679274 0.890001512194424 -12.7001847810821 6.15780233354679 -2.06245411806958 0.0396413439029519 RSPH4A other 1 1 1 -0.138367443679274 -2.06245411806958 0.00948067720402645 0.636320821817184 3.43050371067261 0.185489034697013 0.852915388950158 -34.3009705359718 11.8776696590873 -2.88785355380961 0.00403489833923347 MAK other 1 1 1 0.185489034697013 -2.88785355380961 3.29902069889531e-25 351.876646250365 40.0585428755687 8.78406005289252 2.11056702079169e-17 -586.928480973367 138.697456533898 -4.2317176943322 2.72654073290907e-05 TMEM14C other 4.27355141334898e-21 0.31993228959955 2.81169738509869e-13 8.78406005289252 -4.2317176943322 6.7717999872351e-29 162.063697743331 13.6312591699897 11.8891215934128 4.18105734198388e-29 51.1227736301537 47.1964490097571 1.08319110235571 0.279208820988348 PAK1IP1 essential 9.17646616270229e-25 1 6.11981363146181e-25 11.8891215934128 1.08319110235571 9.30108011969555e-05 153.264958819633 35.2794172332248 4.34431662536914 1.67148179993864e-05 162.997448706757 122.325588077069 1.33248857633992 0.183265886160708 GCNT2 other 0.507559942131786 1 0.147809135568574 4.34431662536914 1.33248857633992 0.0541571752880433 -16.804366344957 81.6436668830366 -0.205825717860408 0.837005201615376 -670.283758450853 282.046557278941 -2.3765004080087 0.0178279911514685 NEDD9 other 1 1 1 -0.205825717860408 -2.3765004080087 2.07867370340991e-22 46.5101724641839 4.59558366329864 10.1206235968729 3.80125971471816e-22 20.9707698389051 14.5298282737399 1.44329096282618 0.149523780760998 CEP85L other 2.58046553541306e-18 1 5.32632511226308e-18 10.1206235968729 1.44329096282618 0.848655147085028 -2.54441729080015 9.20508334213631 -0.276414367608501 0.782336571659142 12.9359350116616 31.8003250749752 0.406786250806014 0.684327670531651 ADTRP other 1 1 1 -0.276414367608501 0.406786250806014 2.66905397985358e-60 158.361964047302 9.75569582043752 16.2327697544181 1.85278298238894e-48 -83.1133298954819 30.8616391828298 -2.69309512055091 0.00730168105325135 ASF1A other 4.10260287243294e-56 1 2.83531379794979e-44 16.2327697544181 -2.69309512055091 3.73271457578865e-49 120.477672356106 9.23195008653356 13.0500783937127 5.56151325893761e-34 -129.9841349758 29.2047966407091 -4.45078034868465 1.04206958290288e-05 MCM9 other 5.63117320903475e-45 0.125694433089745 8.28776705846882e-30 13.0500783937127 -4.45078034868465 2.8077849577521e-27 54.9057911503892 4.83651543710196 11.3523448574556 6.85379794766857e-27 25.0255152484766 15.0358706606028 1.66438750461247 0.0966249481785828 FAM184A other 3.73800411425536e-23 1 9.92087252925025e-23 11.3523448574556 1.66438750461247 1.54390446913916e-41 128.02522752147 12.8150375298639 9.99023430271845 1.09458597962982e-21 -111.039970245297 28.8841167366843 -3.84432632154094 0.000135197223603685 RNGTT essential 2.27602396840495e-37 1 1.52793256896526e-17 9.99023430271845 -3.84432632154094 0.0032264268138909 261.958466146678 116.956387969294 2.23979613850125 0.0255164053959591 -546.124159745632 362.878862900338 -1.50497649651096 0.132923572298916 MAN1A1 other 1 1 1 2.23979613850125 -1.50497649651096 1.051110794936e-11 125.53372586859 183.318371299972 0.684785299904144 0.493777638359256 -2542.18377036473 419.8157995732 -6.05547426502099 2.64770991251523e-09 SERINC1 other 9.51465491576067e-08 3.67449181658863e-05 1 0.684785299904144 -6.05547426502099 9.95910175621879e-39 304.581388375768 26.5660246374194 11.4650721187224 2.31214836264637e-27 -140.336983430404 60.3847968562624 -2.32404497053219 0.0204967048332524 HDDC2 other 1.44984603367033e-34 1 3.35723942256253e-23 11.4650721187224 -2.32404497053219 5.16249138559514e-11 529.599995799368 98.2085018006176 5.39260844111601 1.04376145679277e-07 -329.608813799743 223.228748438149 -1.47655181559676 0.14038416257034 TPD52L1 other 4.51717996239574e-07 1 0.00106432355749159 5.39260844111601 -1.47655181559676 1.30378183133595e-28 255.937164117742 30.0857720887764 8.50691693610283 1.79907196257198e-16 -248.93118215535 69.062944235374 -3.60441022188346 0.000342097135212421 HINT3 other 1.7603662286698e-24 1 2.36038241489443e-12 8.50691693610283 -3.60441022188346 3.20159676653958e-11 374.716082300889 63.9044000457736 5.86369768016734 7.92959046978556e-09 -123.408824561099 146.69478994035 -0.841262492084964 0.40057675043621 NCOA7 other 2.83181234000425e-07 1 8.51875904169063e-05 5.86369768016734 -0.841262492084964 0.571201483581468 0.369988740749875 8.18252514087697 0.0452169390719674 0.963951139532392 -28.5988372106086 28.6804301581758 -0.997155100285552 0.319136670152082 RIPOR2 other 1 1 1 0.0452169390719674 -0.997155100285552 2.40578373034673e-09 226.792962015776 67.8026654897648 3.34489743696008 0.000879877182847382 -599.73705942999 168.080214826213 -3.5681597625877 0.000391250514144435 SASH1 other 1.93160375709539e-05 1 1 3.34489743696008 -3.5681597625877 0.427326938580727 15.1617522824023 16.7903570787937 0.903003563965395 0.366922205118695 -19.4517185827693 41.4945768350449 -0.468777369633062 0.639415883209906 UST other 1 1 1 0.903003563965395 -0.468777369633062 7.80875054392321e-05 19.9828523749194 4.69154665020099 4.25933148806338 2.41452355400138e-05 9.71214270961772 11.6671111152691 0.832437662902445 0.405525897711218 ULBP1 other 0.430496417486486 1 0.2109569229131 4.25933148806338 0.832437662902445 8.58864745244392e-15 101.396121057031 13.7597769071703 7.36902362161068 6.43849871028328e-13 -1.439279588379 30.0413397248115 -0.0479099667845466 0.96180561199515 FBXO5 essential 8.79821045028355e-11 1 7.85754382602971e-09 7.36902362161068 -0.0479099667845466 4.33615719302766e-38 59.7686659581044 6.02654080715678 9.91757425538818 2.04370669071684e-21 -59.2605789882744 13.0197468513883 -4.55159225941135 6.57805922937676e-06 MTRF1L other 6.29696747571477e-34 0.0802983690130021 2.8458615668232e-17 9.91757425538818 -4.55159225941135 5.80872217002329e-10 190.24344727431 33.2521984965405 5.72122914802469 1.74458730643023e-08 -143.859403489242 110.849458183989 -1.29779076818276 0.194907235662415 PPARD other 4.81891591225132e-06 1 0.000184943700354669 5.72122914802469 -1.29779076818276 2.15071965458327e-14 57.0049197423055 7.38520284274201 7.71880217187649 5.62965610852031e-14 1.12420270106006 24.6192964889819 0.045663477896827 0.963595169690413 FANCE other 2.16835555575085e-10 1 7.0533961383651e-10 7.71880217187649 0.045663477896827 8.83418235957056e-24 277.406504540992 29.7921052808704 9.31140991634168 3.0783626968256e-19 -216.246393392784 99.8265163869582 -2.16622197407497 0.03072701518258 MAPK14 other 1.12079271595872e-19 1 4.19796320966106e-15 9.31140991634168 -2.16622197407497 1.72713792704953e-21 424.318092075639 52.8722826091399 8.02534089954892 6.25173294100523e-15 -592.420598547116 177.540353751612 -3.33682222677073 0.000905200168486924 KCTD20 other 2.10555384686608e-17 1 7.98408813895778e-11 8.02534089954892 -3.33682222677073 1.74379293058558e-26 533.87903729841 48.8763278178791 10.9230595082292 2.98031328939869e-25 27.2199485765801 164.122298161683 0.16585161724804 0.868335229280979 STK38 other 2.29919097897709e-22 1 4.27466335098454e-21 10.9230595082292 0.16585161724804 1.0686029556631e-16 638.463942146435 86.4192715054528 7.38798107209397 5.63118879832716e-13 -640.750298201216 290.188115150194 -2.20805148367148 0.0276563096960119 SRSF3 essential 1.16402919960381e-12 1 6.88356518707513e-09 7.38798107209397 -2.20805148367148 2.15727442103902e-46 324.210716584614 26.3936601577996 12.2836588273948 8.56300514135823e-31 -182.153154804378 55.6582907368652 -3.27270479191574 0.00113258719924631 MRPL18 essential 3.23181281015856e-42 1 1.2627863681961e-26 12.2836588273948 -3.27270479191574 2.04392602667125e-24 951.940524869673 92.8981081136132 10.24714651568 1.27875269513394e-22 -335.770365588051 383.650103321923 -0.875199466077829 0.38185812330583 MCM3 essential 2.61867802537121e-20 1 1.79907716678394e-18 10.24714651568 -0.875199466077829 3.22321689362791e-23 141.551051590646 14.3701374598894 9.8503616952691 3.60840488743678e-21 -35.3593282373584 48.6883566390492 -0.726237866262246 0.468006459759834 RNF8 essential 4.05255060035837e-19 1 5.0138785910934e-17 9.8503616952691 -0.726237866262246 0.00127998422964248 42.0763713273099 12.1077222933302 3.47516818671077 0.000551808076584401 90.642781467912 42.8424900084585 2.11572159904843 0.0348281885088816 PHACTR1 other 1 1 1 3.47516818671077 2.11572159904843 0.0623446775091984 -34.9390291855605 16.4276459778249 -2.12684332452279 0.0338841523992539 15.7185851386117 55.743576292037 0.28198020622615 0.778066323111406 MDGA1 other 1 1 1 -2.12684332452279 0.28198020622615 3.52400795626223e-07 95.6387226421172 26.8062202986532 3.56778096936412 0.000392986408026548 -288.589490685811 99.1748898185344 -2.90990482786377 0.0037687579927387 ICK other 0.00244777592641975 1 1 3.56778096936412 -2.90990482786377 7.16571643907864e-13 129.581394315646 30.4336338322626 4.25783509882009 2.44501366727652e-05 -531.971894545953 111.725207456669 -4.76143125312405 2.48863327304438e-06 FBXO9 other 6.80313118726126e-09 0.0310481887145016 0.213571943836604 4.25783509882009 -4.76143125312405 0.000606521167363276 90.1330212261775 23.5457067924582 3.82800236241146 0.000144403765968398 131.483040732875 80.5128909272132 1.63306818595969 0.103040812119631 CD83 other 1 1 1 3.82800236241146 1.63306818595969 6.35602992667213e-23 307.809751152713 47.4769943794358 6.48334535865307 2.02955543421264e-10 -388.512968002671 108.646352808214 -3.57594118864243 0.000380350701755439 MDN1 essential 7.95520705622284e-19 1 2.3145050171761e-06 6.48334535865307 -3.57594118864243 0.0156848996446773 10.063676370851 4.00364011911802 2.51363161309014 0.0122377799483152 -7.78000125266988 13.8578437410436 -0.561414993418305 0.574746286447406 GLP1R other 1 1 1 2.51363161309014 -0.561414993418305 1.10319613010091e-21 169.43436729167 19.7750957407595 8.56806811521222 1.09365355664534e-16 -176.871273583531 67.7366303225693 -2.61116138699623 0.00927296958422254 SAYSD1 other 1.35097398092157e-17 1 1.44034173410191e-12 8.56806811521222 -2.61116138699623 0.676700464359933 -18.8456161191575 27.6323958623993 -0.682011658091568 0.495534657059162 -76.6994438638507 103.866621499977 -0.738441693358322 0.460578589726204 BMP5 other 1 1 1 -0.682011658091568 -0.738441693358322 0.283057470618085 -1.21679323018076 7.50529402935112 -0.162124658330802 0.871268221164447 -24.6238883557763 17.2352066821564 -1.42869701593247 0.153668425419871 BACH2 other 1 1 1 -0.162124658330802 -1.42869701593247 0.253572571403106 -85.8279056560368 54.7672663700991 -1.56713875540255 0.11766804108286 -185.634755194949 198.034816856435 -0.937384436442429 0.348979889980596 RBM24 other 1 1 1 -1.56713875540255 -0.937384436442429 0.00246611560711498 57.3151201575905 49.9204928800742 1.14812809030714 0.251424046561329 -521.08851170794 182.016618474681 -2.86286228188787 0.00436136012810954 CAP2 other 1 1 1 1.14812809030714 -2.86286228188787 9.03079819780592e-17 112.847177662833 18.4679529408135 6.11043238113548 1.96685258321005e-09 -301.568359123217 70.1481787697394 -4.29901908235011 2.05373470644251e-05 ZNF451 other 9.84898851452713e-13 0.243264875978115 2.16216104472281e-05 6.11043238113548 -4.29901908235011 3.91886891193369e-08 104.699364164794 20.4830009402173 5.11152464770053 4.51798804503904e-07 -101.626064150971 77.8020832249212 -1.3062126351704 0.19206561106738 BAG2 other 0.000292230054762896 1 0.00444524843751391 5.11152464770053 -1.3062126351704 9.84207392981057e-07 91.4480430765755 20.8437318524994 4.38731623126353 1.39412312339334e-05 -121.26255610297 79.1618152289058 -1.5318314234246 0.126181659883284 RAB23 other 0.00657056855554154 1 0.124160605369411 4.38731623126353 -1.5318314234246 0.177510150213358 -11.6523562087875 7.25656703684863 -1.60576704516299 0.108912961680166 -27.1867516640232 16.4905537823521 -1.64862575404338 0.0998092009427511 FHL5 other 1 1 1 -1.60576704516299 -1.64862575404338 0.000156902639267194 11.2164020509438 3.41272578100086 3.2866402901127 0.00108015949826225 -3.99242268488864 7.75542177867821 -0.514791174332376 0.606910768747099 GPR63 other 0.831897793394662 1 1 3.2866402901127 -0.514791174332376 1.7082230752723e-15 98.9599638187907 20.9757333010819 4.71783095247908 3.04781658951638e-06 -168.367959122411 47.9609562527258 -3.51052131311169 0.000485038208830178 FBXL4 other 1.79192600596064e-11 1 0.028460511312904 4.71783095247908 -3.51052131311169 2.9653079931657e-49 499.904800844302 42.2037327980092 11.8450375761047 6.67887733568309e-29 -356.015834557959 96.5360192846601 -3.68790672327351 0.00024924802856024 CCNC other 4.47464976168704e-45 1 9.7705296543708e-25 11.8450375761047 -3.68790672327351 2.43899884623618e-21 276.733111508726 27.7527808070279 9.97136515554682 1.3975029888948e-21 47.3143961444833 100.237274550501 0.472023968694853 0.637103591120608 E2F3 other 2.96557869713858e-17 1 1.94937691920936e-17 9.97136515554682 0.472023968694853 0.000358502815030275 392.838231782365 179.941510161347 2.18314401957681 0.0295009398639205 -1072.91502414769 477.855645358206 -2.2452701659377 0.0251977354286514 PTP4A1 other 1 1 1 2.18314401957681 -2.2452701659377 0.443248910667832 -7.92234184677263 22.3278311979194 -0.354819139241381 0.722866766180825 -62.0766064984596 50.5505341608113 -1.22801089106164 0.21999001687087 SIM1 other 1 1 1 -0.354819139241381 -1.22801089106164 4.02521101777404e-17 310.117127632143 56.2150279372857 5.5166232057754 5.42427320112622e-08 -396.877456170455 127.52339645695 -3.11219326960472 0.00195775583820812 ASCC3 other 4.43980775260476e-13 1 0.000562280160028744 5.5166232057754 -3.11219326960472 0.0347645101527279 22.42380465387 11.7993783034724 1.900422554235 0.0579241520909593 -13.0189430015565 26.3900043700139 -0.493328565581805 0.621986347933945 BVES other 1 1 1 1.900422554235 -0.493328565581805 0.602204002331491 -13.6213905561825 60.5435022459974 -0.224985176788034 0.822075917523258 -140.450428137688 144.296384181923 -0.973346830095299 0.330816754132243 COL9A1 other 1 1 1 -0.224985176788034 -0.973346830095299 1.95467781286825e-17 101.879928438877 32.5389694960176 3.13101275230447 0.00183704726539376 -461.4225300929 75.8289870873219 -6.08504145731951 2.21861512054213e-09 MED23 other 2.1720379856592e-13 3.08343129452945e-05 1 3.13101275230447 -6.08504145731951 6.47283507691734e-18 80.1527475748145 10.7028915599436 7.48888719706293 2.86367598735973e-13 -54.5558589811651 31.5039751127701 -1.73171349919747 0.0838978010951093 WASF1 other 7.29164871414739e-14 1 3.53005338961834e-09 7.48888719706293 -1.73171349919747 1.37759334659809e-06 16.9531710464872 3.837602894592 4.41764599207953 1.20655599836354e-05 -18.9696105006303 13.3560936658621 -1.42029630633067 0.156099602865402 GPLD1 other 0.00908798330750757 1 0.108010892973504 4.41764599207953 -1.42029630633067 0.00384987889151981 75.764534227999 30.4659721043855 2.48685759864833 0.013188640189545 -150.055987215967 106.209897394755 -1.4128248957651 0.158283312099555 ALDH5A1 other 1 1 1 2.48685759864833 -1.4128248957651 8.73468627727798e-71 1615.41269393719 80.498548196236 20.0676003497505 6.57771187824315e-67 507.696190311093 269.665126734189 1.88269130851144 0.0602949166962602 CRYBG1 other 1.3522167825854e-66 1 1.01934800977134e-62 20.0676003497505 1.88269130851144 0.958644275719286 -3.77431493994352 13.2078863944921 -0.285762220177596 0.775170031986611 -2.67770670085714 31.2282755234985 -0.0857462237657736 0.931699997383623 VNN1 other 1 1 1 -0.285762220177596 -0.0857462237657736 0.181375828196367 -1.40595528442034 5.14666126754549 -0.273178126815185 0.784820929457379 -21.2691210825844 12.1685901353643 -1.74787061163085 0.081055832753128 VNN2 other 1 1 1 -0.273178126815185 -1.74787061163085 1.24199106336544e-21 180.239351620346 19.8279968883873 9.09014423569468 1.88461837654735e-18 -129.306288478326 69.1129737793021 -1.87094088718045 0.0618948557902342 ACOT13 other 1.51870667228326e-17 1 2.54687327406608e-14 9.09014423569468 -1.87094088718045 1.24137263587954e-35 190.570599393685 21.5625140758579 8.83805101405377 1.36691857259867e-17 -262.031136896367 51.8269225382594 -5.05588840824828 5.87298240011869e-07 SMAP1 other 1.77925939900615e-31 0.00753621101583231 1.8266132885636e-13 8.83805101405377 -5.05588840824828 2.24110136696352e-12 1523.52623107833 405.13439955929 3.76054522335215 0.000188200015820655 -3826.86319341242 949.999805585047 -4.02827787007355 6.43076657473525e-05 RPS12 essential 2.08803414359991e-08 0.735679696149712 1 3.76054522335215 -4.02827787007355 1.99105132216681e-28 1035.59915294727 103.938676373034 9.96355917820746 1.41187188491171e-21 -1245.21541934867 362.291312393337 -3.43705569731342 0.000633475945003471 C6orf62 other 2.6833398668842e-24 1 1.96927890507485e-17 9.96355917820746 -3.43705569731342 1.11728366043506e-35 145.581413529478 16.625997096737 8.75625159095271 2.58574224597424e-17 -206.737927555435 39.7326250905304 -5.20322850766553 2.784563000532e-07 B3GAT2 other 1.60184958396575e-31 0.00361603351249086 3.44214007784091e-13 8.75625159095271 -5.20322850766553 3.33716962101301e-17 157.902951885171 17.756044250553 8.89291272633844 8.97438367470513e-18 71.020231745237 61.6271581935477 1.15241776234739 0.249660297118505 GMNN other 3.68808533566084e-13 1 1.20265715624723e-13 8.89291272633844 1.15241776234739 0.654698985038555 11.0211491124734 12.7182940838604 0.86655875700022 0.386572281105559 3.79562886473725 29.8198852651569 0.12728515991885 0.898762531312429 EYA4 other 1 1 1 0.86655875700022 0.12728515991885 0.420432857496209 -0.336538854686282 6.29411311491677 -0.053468828497648 0.957378667033459 -21.7333727976652 18.0332465216312 -1.20518359085236 0.228674348157714 SOBP other 1 1 1 -0.053468828497648 -1.20518359085236 1.84369054578416e-71 983.671233952943 52.5986261733696 18.7014624813713 2.47411352367535e-60 -117.579532601113 150.470536588049 -0.781412330063104 0.434908274330806 SNX3 other 2.85550791731051e-67 1 3.82398986219262e-56 18.7014624813713 -0.781412330063104 1.19090928757249e-33 357.883667092732 37.9085887152227 9.44070141416314 1.14721597019739e-19 -325.202869624918 86.3843519790675 -3.7646039146502 0.000185354812936066 HBS1L other 1.68180209590988e-29 1 1.57168587917042e-15 9.44070141416314 -3.7646039146502 1.2208291508152e-09 130.620187807011 26.1087837333127 5.00292120618205 7.64625580085584e-07 -252.543344936562 98.1462683053302 -2.57313242059196 0.0103435566006043 TRIM38 other 9.94609509169143e-06 1 0.00741075112218948 5.00292120618205 -2.57313242059196 1.22403216128717e-18 36.3856411764472 9.74681370206581 3.73308060343201 0.000209734252199034 -135.823439292246 22.4253177888706 -6.05670075987301 2.64416320092265e-09 PEX7 other 1.40261845361897e-14 3.66983410656054e-05 1 3.73308060343201 -6.05670075987301 2.6634337663166e-50 123.261873743785 9.38010758244145 13.1407739901105 2.97538586070846e-34 -119.228771352066 28.442738576235 -4.19188788844991 3.25221716741138e-05 ZBTB24 other 4.03110700532017e-46 0.379501221265234 4.43719293407452e-30 13.1407739901105 -4.19188788844991 3.44461248531156e-27 143.800159940871 19.955677035243 7.20597751140741 1.9628564407249e-12 -317.770109710381 59.6667589193475 -5.32574779434418 1.48080912565811e-07 FIG4 other 4.58099014421584e-23 0.00194563511020219 2.3717194373279e-08 7.20597751140741 -5.32574779434418 9.26386098584702e-11 1748.58170099376 320.88808849144 5.44919479315731 7.78620263806737e-08 -977.963657801222 734.639549340339 -1.33121563994121 0.183694740081373 PERP other 8.00027034737749e-07 1 0.000800810941325229 5.44919479315731 -1.33121563994121 4.70955952967277e-09 229.741103097491 169.284820067447 1.35712760899622 0.175322714928511 -1879.54586119688 387.559801640401 -4.84969249452971 1.63093979426018e-06 ARFGEF3 other 3.71819724867665e-05 0.0205058060332332 1 1.35712760899622 -4.84969249452971 0.000799827576764139 14.31278073256 4.28652278860531 3.33901892942388 0.000898758708019136 -2.29952005937431 12.2702463268491 -0.187406185509302 0.851412566535643 SLC16A10 other 1 1 1 3.33901892942388 -0.187406185509302 2.61320671406968e-15 183.05989070989 30.7091267456637 5.96109072804354 4.60134908299698e-09 -178.270366676895 69.4440057893378 -2.56710949563722 0.0105309140681268 HECA other 2.72426799941764e-11 1 4.98694213615213e-05 5.96109072804354 -2.56710949563722 3.65914374787822e-10 293.491733718465 45.8847505703689 6.39628046508318 3.51060609445311e-10 126.708156086117 100.601183585161 1.259509595917 0.208402798001398 ADGRG6 other 3.0678261182211e-06 1 3.97892094745316e-06 6.39628046508318 1.259509595917 2.26151442757061e-05 86.7594792292126 27.0911637599138 3.20250100726898 0.00144373500925417 -86.1567282606085 59.1333059241903 -1.45699157038611 0.145707568149888 PHACTR2 other 0.132705666609843 1 1 3.20250100726898 -1.45699157038611 1.03105095242703e-06 29.4130029404752 7.90447203736254 3.72105850984696 0.000219255305273476 -28.1264672593184 17.2876832719451 -1.62696567358813 0.104329895296932 EPM2A other 0.00687092354697375 1 1 3.72105850984696 -1.62696567358813 3.01665843647168e-25 1301.26371984281 127.529110244219 10.2036603043092 1.77915317922877e-22 -481.443701561122 439.069478298436 -1.09650915255349 0.273343866831444 SLC39A7 essential 3.91049433119824e-21 1 2.49971021681642e-18 10.2036603043092 -1.09650915255349 0.0430202462329971 -19.545332228016 25.6419589959098 -0.762240210708305 0.446246400254021 -132.91329225193 53.8211550461955 -2.46953622860469 0.0138341646855982 CCR6 other 1 1 1 -0.762240210708305 -2.46953622860469 2.64533721147506e-05 16.6874386170458 32.5249113624408 0.51306638259793 0.608114711312076 -481.226915549024 114.437938274189 -4.20513444060853 3.05428750254054e-05 PHF1 other 0.15435542628957 0.357046209046989 1 0.51306638259793 -4.20513444060853 8.59372182754489e-06 356.39805197169 93.8754096670495 3.79650063031135 0.000163420221843171 -567.07507052179 332.637499760646 -1.70478394928364 0.0888109692190735 CUTA other 0.0525420152536095 1 1 3.79650063031135 -1.70478394928364 0.0111672845577419 -0.911338402287356 1.0986102929237 -0.829537469435173 0.407162863064601 -6.77926043832897 2.30948945481204 -2.93539354518538 0.0034715138375251 PACRG other 1 1 1 -0.829537469435173 -2.93539354518538 0.00221331715339041 255.301352245727 79.4351595825559 3.21395907791179 0.00138648471118677 47.8532446587482 166.295511926644 0.287760289525174 0.773639426234174 QKI other 1 1 1 3.21395907791179 0.287760289525174 0.00398964312572634 77.1020499457698 24.8996973878655 3.09650550144214 0.00205889581519301 21.0079615574214 52.3707977084629 0.401138849829408 0.688475124430346 PDE10A other 1 1 1 3.09650550144214 0.401138849829408 1.01979342647776e-14 448.585408511238 56.6268772672003 7.92177549177817 1.34441562517986e-14 -90.7358147171219 271.637596614191 -0.33403260759222 0.738484634125798 MDFI other 1.04090315040584e-10 1 1.70673563616583e-10 7.92177549177817 -0.33403260759222 3.67860441673642e-25 107.093014480261 9.73477711975494 11.001075131236 1.52831930995858e-25 36.7464278884161 46.699419120473 0.786871198410827 0.431701826048107 TFEB other 4.76232127790697e-21 1 2.1954306887555e-21 11.001075131236 0.786871198410827 0.0790623855622355 -398.90054825211 195.347901151598 -2.04200068647037 0.041638583448152 -735.940318083756 397.723575002537 -1.85038143157358 0.0648066300600689 SMOC2 other 1 1 1 -2.04200068647037 -1.85038143157358 5.5360267423599e-19 203.699684055473 23.6721196075125 8.60504624988577 8.33956992754711e-17 -214.188080765909 113.870335125191 -1.88098226399727 0.060512151202804 CCND3 other 6.3974325034711e-15 1 1.10140700033115e-12 8.60504624988577 -1.88098226399727 2.09692108907516e-47 179.911662015773 11.7528134290477 15.3079654588162 3.38031407514215e-44 -86.7358897126251 56.5347263370866 -1.53420552874821 0.125564753781159 BYSL essential 3.1499948600087e-43 1 5.1414577082912e-40 15.3079654588162 -1.53420552874821 5.68879863929596e-31 105.497046765809 30.2922059195702 3.48264656083209 0.00053680148993291 -537.016593763279 60.8339396703798 -8.82758204832743 1.49676309826025e-17 FAM120B other 7.85623092086771e-27 2.28406048794514e-13 1 3.48264656083209 -8.82758204832743 1.12081425937904e-45 67.8177092312085 6.73892491049417 10.0635798932259 6.01830358390391e-22 -77.6545156642376 13.5333607772477 -5.73800676287227 1.59928476158005e-08 TBP essential 1.67685021345697e-41 0.000217295499255937 8.41719939244801e-18 10.0635798932259 -5.73800676287227 0.000159676291104271 1.28382347089856 0.562363917167779 2.28290512905638 0.0228223038632674 -7.70482693750139 2.69107616653232 -2.86310251390236 0.00435749788940924 GUCA1B other 0.84564563768822 1 1 2.28290512905638 -2.86310251390236 0.0805097607727352 1.34286942735309 1.30484547539949 1.02914057845965 0.303876068850767 -10.4619117711156 6.20763860921456 -1.68532874249252 0.0925050416027875 PRPH2 other 1 1 1 1.02914057845965 -1.68532874249252 1.4252552795338e-30 205.226445518584 18.3114824081753 11.2075276563605 2.42688810832932e-26 -236.16942210903 88.1235763808671 -2.67997999863639 0.00758870810828824 BICRAL other 1.96029611147078e-26 1 3.50321298437337e-22 11.2075276563605 -2.67997999863639 3.7826298819323e-73 473.639780890671 22.9429745117508 20.6442185884871 3.58147291787643e-70 -88.227102008839 113.201102813559 -0.779383767613537 0.436096382435007 PPP2R5D other 5.86458936894783e-69 1 5.55844596854422e-66 20.6442185884871 -0.779383767613537 5.49769412914131e-52 204.646400051003 12.3490015596999 16.5718984698205 3.8898054105523e-50 -46.4377429116403 66.3041379658528 -0.7003747328041 0.483996071300994 MRPL2 essential 8.34330061038485e-48 1 5.96190475275351e-46 16.5718984698205 -0.7003747328041 8.08844080374421e-25 1029.74489253447 96.7666923519482 10.64152207238 3.84489343325931e-24 -310.263813319295 519.459466259899 -0.597282046957754 0.550568983741836 PTK7 other 1.04292355723478e-20 1 5.47705069567788e-20 10.64152207238 -0.597282046957754 3.38934193264676e-17 224.354448289953 29.0126893544632 7.73297661409109 5.17631702297177e-14 -426.083932764404 155.663179735569 -2.73721719862211 0.00640037016902437 SRF essential 3.74488390138141e-13 1 6.49058391510431e-10 7.73297661409109 -2.73721719862211 7.02103490112801e-26 119.850372101502 13.3750395709955 8.96074897313983 5.23649307504529e-18 -339.572378696323 71.7617440862967 -4.73194155214471 2.84366914778459e-06 CUL9 other 9.19123678906668e-22 0.0353695568601448 7.0404649393984e-14 8.96074897313983 -4.73194155214471 3.7207322648358e-07 89.327707133846 17.0419947080703 5.24162274804278 2.28716298540914e-07 -41.5835214527487 90.1395020316329 -0.461324064538938 0.64475188353323 DNPH1 other 0.00257921466543161 1 0.002289221432096 5.24162274804278 -0.461324064538938 4.96596657541387e-05 80.2322489429491 19.9326936362139 4.02515838587828 6.57249729467811e-05 -24.8704857808887 58.2891655372949 -0.426674246433943 0.669799526753959 DUSP22 other 0.280924729171163 1 0.552352672644748 4.02515838587828 -0.426674246433943 0.00035120682924626 480.983363820164 181.922064504564 2.64389789732239 0.00844911691841947 -965.680508723985 526.524767723743 -1.83406473526172 0.0672291469939283 EXOC2 other 1 1 1 2.64389789732239 -1.83406473526172 2.03533939564662e-24 457.169508807952 69.5285679440394 6.57527577981915 1.15631203591389e-10 -645.491227528085 152.752821975026 -4.22572374887855 2.80020968556439e-05 COX7A2 other 2.60788036764201e-20 0.328352587729281 1.32987447250456e-06 6.57527577981915 -4.22572374887855 6.4408987823712e-18 540.308336696853 133.343811816738 4.0519940845806 5.83122641035581e-05 -1477.43468610068 292.72131566948 -5.04723983875809 6.15346290887497e-07 TMEM30A other 7.2563165682194e-14 0.00788689341030504 0.492388758090444 4.0519940845806 -5.04723983875809 1.79075908783401e-11 272.76648568888 38.0684635918905 7.16515614113164 2.65689134775312e-12 183.596996670997 112.958100879161 1.62535484610707 0.104689380951041 GMDS other 1.60237123179387e-07 1 3.20022562836863e-08 7.16515614113164 1.62535484610707 1.64084920230115e-34 229.922403686279 47.4557340878116 4.84498676726468 1.66086754551302e-06 -875.193069826852 105.76933445834 -8.27454454836879 1.03192240311983e-15 SENP6 essential 2.33312348075201e-30 1.55799644423031e-11 0.0157666156095551 4.84498676726468 -8.27454454836879 4.71092710178212e-05 -2.90075303573086 1.4046746353089 -2.06507112950962 0.0394019967309406 -14.0551523802379 3.12471027288787 -4.49806578939174 8.43211002843359e-06 IMPG1 other 0.267533550110206 0.102298358864956 1 -2.06507112950962 -4.49806578939174 1.43033544292411e-28 1100.75775370146 95.0931978062825 11.5755677492711 7.80518933537184e-28 -273.670754751251 503.357862497058 -0.543690235399572 0.586879036072308 VEGFA other 1.93023768022608e-24 1 1.13612335965673e-23 11.5755677492711 -0.543690235399572 3.23291118700103e-15 282.073262803508 42.4776105587912 6.64051624121146 7.69466485992886e-11 -372.139862288591 129.091965906877 -2.8827499811804 0.00410071138405818 PRPF4B other 3.36222763448107e-11 1 8.89041577916181e-07 6.64051624121146 -2.8827499811804 5.26978883102856e-20 197.949051638554 27.3219841093671 7.24504673036132 1.51706365759122e-12 -105.828571638775 58.6525353268306 -1.80433072584271 0.0717417344302276 TTK essential 6.24153789147023e-16 1 1.83792262117176e-08 7.24504673036132 -1.80433072584271 9.39142236283064e-79 2448.1869427988 108.519595112379 22.5598606432649 1.41175481995347e-79 1723.60804124591 575.29654369632 2.99603406300967 0.00286268363248492 SLC29A1 other 1.46008443474928e-74 1 2.19838460563154e-75 22.5598606432649 2.99603406300967 2.93879325183466e-07 15.6461698559184 3.83746949686738 4.07721022113421 5.24670912469185e-05 -18.240186879001 10.974331270487 -1.66207729923863 0.0970797726687101 WISP3 other 0.0020512776897806 1 0.444868466682622 4.07721022113421 -1.66207729923863 1.10670586984609e-21 99.8660647108897 11.58075221044 8.62345233678872 7.39246354192976e-17 -137.479446074129 46.3805345996019 -2.96416260099143 0.00317031770452571 BTN2A1 other 1.35516133762654e-17 1 9.77209755607695e-13 8.62345233678872 -2.96416260099143 0.92135953669777 -16.7794563139912 94.1747354380648 -0.17817364960931 0.858653671417101 -109.091755693139 269.530566945748 -0.404747249743652 0.685824178334789 LAMA4 other 1 1 1 -0.17817364960931 -0.404747249743652 0.0788759647845951 93.2050263242819 80.1931790270164 1.16225628482545 0.245650553666279 -179.877194530717 175.231857744119 -1.02650965895357 0.305116167843803 FAM46A other 1 1 1 1.16225628482545 -1.02650965895357 0.86761434426012 -6.34145683879723 29.0212411349817 -0.218510876543917 0.827115675759138 -71.9628095427118 136.923628665371 -0.525568963108495 0.599408787807843 CLIC5 other 1 1 1 -0.218510876543917 -0.525568963108495 2.15599292457938e-08 166.653346361749 34.245199792437 4.86647318082092 1.49703528416904e-06 -156.496498812512 81.4763421680233 -1.92075999791179 0.0552931329111441 FBRSL1 other 0.000163532063329346 1 0.0142461600244925 4.86647318082092 -1.92075999791179 0.00857974120340509 255.670493619475 104.797053244995 2.43967254519807 0.0150292631765852 -607.439634480186 492.32225329811 -1.23382526467348 0.217817986775134 ENPP5 other 1 1 1 2.43967254519807 -1.23382526467348 0.004830142408624 -20.4449641437603 6.23811308129619 -3.2774276255204 0.00111556703928812 -23.9406806645832 18.5514633632672 -1.29050092684262 0.197434227514332 LY86 other 1 1 1 -3.2774276255204 -1.29050092684262 4.62549170160406e-08 71.5905738576159 14.6307563755571 4.89315603513287 1.31721513542337e-06 -98.9268211064821 56.6358304881661 -1.7467179390466 0.0812633738116108 PRSS16 other 0.000342933954756925 1 0.0125925766946475 4.89315603513287 -1.7467179390466 0.438380135927427 -12.0045687542714 15.8846732859783 -0.755732808484517 0.450140156711418 -44.9325191174384 35.0148989957833 -1.28324000371526 0.199960489114133 TBX18 other 1 1 1 -0.755732808484517 -1.28324000371526 2.51264244633397e-19 149.483634520947 75.5392054090489 1.97888809806093 0.048336194115216 -1287.95240429229 166.18824230292 -7.74996104685117 4.58980171774386e-14 ERBIN other 2.93300752760565e-15 6.83375577754883e-10 1 1.97888809806093 -7.74996104685117 0.00202178373825613 18.7928595700411 29.6116140254085 0.634644891491418 0.525930326598823 245.727307284714 70.5857484244474 3.48125950024787 0.000539681671669912 PCDHB2 other 1 1 1 0.634644891491418 3.48125950024787 1.74671917067844e-29 135.841578924399 17.816450441408 7.62450294861674 1.1133407517221e-13 -291.417674032601 44.7691451620869 -6.50934193578016 1.72919474814077e-10 HARS2 essential 2.37728479129336e-25 2.46133580450357e-06 1.38477322699195e-09 7.62450294861674 -6.50934193578016 1.49921330200593e-30 40.438200397224 23.6662367192684 1.7086873961799 0.0880782217021383 -566.603539067009 53.0055386051905 -10.6895157369748 2.42361850894828e-24 NUDT12 other 2.06156821158836e-26 3.77018095251994e-20 1 1.7086873961799 -10.6895157369748 4.90486988970876e-11 27.0577920696005 3.83904694998929 7.04804927422833 5.76966414834367e-12 16.6078925223699 17.4777838468902 0.950228739974085 0.342435773366961 CEP72 other 4.29568504940693e-07 1 6.88609416104817e-08 7.04804927422833 0.950228739974085 1.421817880121e-07 220.28243282038 89.6349597565234 2.45755041803707 0.014299133426742 -754.829209468478 198.890518999023 -3.79519955635585 0.000164066142034899 MAN2A1 other 0.00101802160216664 1 1 2.45755041803707 -3.79519955635585 0.0412846811230743 -97.1431276964785 51.6269953365551 -1.88163434775169 0.0604183830340494 -460.971387746817 240.531923316766 -1.91646656040639 0.0558284321222673 SEMA5A other 1 1 1 -1.88163434775169 -1.91646656040639 0.00340966450097243 -123.757521443941 47.0920938054241 -2.62798935964249 0.0088334590776455 -562.895719779839 218.38692501622 -2.5775156627991 0.0102153815316305 C7 other 1 1 1 -2.62798935964249 -2.5775156627991 6.89636599281732e-22 184.871370189368 18.1512467627168 10.185050790511 2.10475510725209e-22 251.162720525055 83.0856859294415 3.02293611366884 0.00262219775946933 PAPD7 other 8.48115089796674e-18 1 2.95549712160339e-18 10.185050790511 3.02293611366884 0.0561972266256355 65.9656486832267 47.1591364825827 1.39878830706728 0.162464699747879 -393.450914038526 228.180953016356 -1.72429341203744 0.0852412846706729 GHR other 1 1 1 1.39878830706728 -1.72429341203744 5.68071268965508e-08 438.484962264937 80.1598596729546 5.47013136068249 6.99806678201149e-08 -481.339465438981 375.622626754361 -1.28144427719407 0.200608779730187 HMGCS1 essential 0.000419236596496545 1 0.000721360723889744 5.47013136068249 -1.28144427719407 4.98096884256123e-15 793.758323876798 95.463873671135 8.3147508408388 7.42995071001113e-16 106.636033966492 467.182825597111 0.228253326372174 0.819535235379681 DAP other 5.1448427174815e-11 1 9.64481901666545e-12 8.3147508408388 0.228253326372174 1.65946507030952e-14 18.6364659068995 7.93787304617945 2.34779087527349 0.019242424314909 -119.892880803229 18.4193886398695 -6.5090586418116 1.7197065413956e-10 NME5 other 1.68103811622354e-10 2.44800226167663e-06 1 2.34779087527349 -6.5090586418116 5.50463283810851e-24 165.360395972468 35.0898634728848 4.7124833101801 3.11196661778071e-06 -609.457789619568 81.4240576621606 -7.48498425549229 2.89912922478091e-13 BRD8 essential 7.00189297007402e-20 4.28288360376883e-09 0.0290315365772762 4.7124833101801 -7.48498425549229 4.86105709729608e-07 50.2396943921318 41.2211531774081 1.21878430173726 0.223455291254014 517.611005935866 95.6353196753452 5.41234146226528 9.3482951884122e-08 KIF20A essential 0.00333225464019646 0.00123855562951273 1 1.21878430173726 5.41234146226528 0.00146920558423431 190.276381181149 60.6761795936976 3.13593213111448 0.00181018775608782 -382.23289928795 284.318593718088 -1.34438235040986 0.179412073416066 NNT other 1 1 1 3.13593213111448 -1.34438235040986 0.0141540331549032 -9.96489113328704 282.93423071601 -0.0352198145415962 0.971918162061661 -3889.9114646298 1340.07408627621 -2.90275851497066 0.00385809121281635 MRPS30 other 1 1 1 -0.0352198145415962 -2.90275851497066 3.86049331534253e-18 1332.69989582118 198.615242494834 6.7099578012289 4.88967091459596e-11 -1688.01130078406 465.513866330582 -3.62612463961563 0.00031470483471853 HSPA9 essential 4.37162263029389e-14 1 5.67837483312029e-07 6.7099578012289 -3.62612463961563 2.28337649513706e-42 253.061840919697 31.1480439189504 8.12448581291921 3.07581130564168e-15 -638.620355070572 73.8227553164874 -8.65072500115617 5.87160609580051e-17 MRPS27 essential 3.37802718690576e-38 8.930125711103e-13 3.94903413531335e-11 8.12448581291921 -8.65072500115617 4.48880155065018e-28 133.564812305454 22.1763532022742 6.02284835054651 3.15719781404591e-09 -394.577953346627 52.7306198373314 -7.48289996521679 2.94113748549563e-13 PFDN1 essential 6.02980712298839e-24 4.34464829357415e-09 3.44481853490549e-05 6.02284835054651 -7.48289996521679 0.336833139996921 7.57110967130261 15.6340141364091 0.484271640363349 0.628388003919711 -42.1731161895262 37.1743382890345 -1.13446851055224 0.257097716004682 HBEGF other 1 1 1 0.484271640363349 -1.13446851055224 0.129105093874644 -32.7094575438155 84.0650333868104 -0.38909706242914 0.697356883188635 323.214880841993 189.833543690392 1.70262259534668 0.0892110159939229 LOX other 1 1 1 -0.38909706242914 1.70262259534668 0.474266283257492 -15.6190879418846 13.0037762393854 -1.20111940211475 0.230231448337203 -21.1607815702035 30.3856490925016 -0.696407093552116 0.486473566371377 GZMK other 1 1 1 -1.20111940211475 -0.696407093552116 4.84958883079629e-09 33.1786016095663 7.31341178516893 4.53667899253945 7.03956973327342e-06 -42.8662975426398 17.318897863511 -2.47511694337977 0.0136233961595088 TMCO6 other 3.82535566973211e-05 1 0.0641375198398541 4.53667899253945 -2.47511694337977 0.00639289945635211 -3003.03416522989 3049.12582723602 -0.984883647111439 0.325117450050288 -22829.2385534503 7154.15823683589 -3.19104467607458 0.00149907114595038 SPARC other 1 1 1 -0.984883647111439 -3.19104467607458 3.76575981394333e-07 65.3317300640497 48.3778490872573 1.35044718392116 0.177432045228064 -460.949919567693 106.509129137153 -4.32779728180974 1.79158407823161e-05 HMGCR essential 0.00260929497508133 0.212965599379391 1 1.35044718392116 -4.32779728180974 7.19004065876849e-27 111.32130945065 33.6608293899653 3.30714695591654 0.00100463300583087 -652.291466079629 74.118934213652 -8.80060504107306 1.79936489072966e-17 COL4A3BP other 9.5253658647365e-23 2.7449311408081e-13 1 3.30714695591654 -8.80060504107306 2.97179694311466e-34 321.888584722831 39.6798790221299 8.11213624273679 3.35669535088895e-15 -796.475925048148 111.198964811293 -7.16261996143385 2.60005186863401e-12 FAF2 essential 4.21876294044557e-30 3.80491590455902e-08 4.30664013519052e-11 8.11213624273679 -7.16261996143385 0.0168870324121503 29.8932990561808 14.7995714369412 2.01987599327127 0.0438914266277446 92.6318123142565 35.2830631665665 2.62539031480783 0.00890122318685747 PCDHB3 other 1 1 1 2.01987599327127 2.62539031480783 0.355073789666562 22.4649249457925 16.8675656498753 1.33184155983757 0.183476209185595 -1.30582597882762 40.2221490030516 -0.0324653458652483 0.974112991966594 PCDHB5 other 1 1 1 1.33184155983757 -0.0324653458652483 0.00731177272367926 -3.50237874259884 9.14969621477374 -0.382786341796097 0.702029093089187 62.0354679045203 22.2753447574835 2.78493862069987 0.00554206675243795 PCDHB6 other 1 1 1 -0.382786341796097 2.78493862069987 0.0157211428558492 4.15843663813036 7.37988501235739 0.563482578816227 0.573340659940204 51.2398124214126 17.9666602105774 2.85193863638866 0.00451204910869573 PCDHB7 other 1 1 1 0.563482578816227 2.85193863638866 5.88788364437218e-07 76.134976525822 25.8769833245134 2.94218903227792 0.00339844137867705 -166.20817453742 57.0026573152443 -2.91579695343379 0.00369463778856527 PDE8B other 0.00400964876181746 1 1 2.94218903227792 -2.91579695343379 1.0252308471202e-16 27.3801945989189 13.050380362312 2.09803805243789 0.0363632950245924 -259.430911501022 35.1631885363027 -7.37791202391058 6.05973901908978e-13 CLK4 other 1.11709153102217e-12 8.92175375780588e-09 1 2.09803805243789 -7.37791202391058 0.903074379304944 -0.532869330304594 2.87872816987029 -0.185105817173632 0.853215540520169 2.23506329528885 7.00785453460502 0.318936884927053 0.749897702614508 PCDHB15 other 1 1 1 -0.185105817173632 0.318936884927053 0.144914653139319 -13.9533482796843 8.65888029475133 -1.61144949516652 0.107659665478672 10.0655708533341 19.7728314909006 0.509060670342853 0.610915351686575 ITK other 1 1 1 -1.61144949516652 0.509060670342853 2.84253359998064e-07 231.569061347999 43.0649484949471 5.37720511555167 1.13290492337647e-07 45.3521263891074 115.308890693995 0.393309883705863 0.694247595194718 RNF130 other 0.00198636247966647 1 0.00115273075953556 5.37720511555167 0.393309883705863 1.17760478783054e-15 14.487193845989 7.51944610167482 1.92663045257578 0.0545443808286269 -124.632003500341 17.3597693560029 -7.17935825899923 2.30140054784177e-12 THG1L essential 1.24237305116122e-11 3.3699408222047e-08 1 1.92663045257578 -7.17935825899923 0.0883182357383341 -14.0813607110722 17.2551937986537 -0.816065057013199 0.414820766509366 58.3450899371323 38.1971109866386 1.52747389606354 0.127225480936834 ARSB other 1 1 1 -0.816065057013199 1.52747389606354 3.14826952971091e-07 200.994995341923 51.8145472993605 3.87912286834557 0.000117623027492643 -287.299411418674 119.621655403881 -2.40173412120623 0.0166507070825302 CLINT1 other 0.00219245490049068 1 0.964861694522147 3.87912286834557 -2.40173412120623 0.0262394795126316 -69.7840008120236 166.319852985642 -0.419577095333578 0.674960371850057 -962.172361277526 367.17934608768 -2.62044249364659 0.00902744183429119 THBS4 other 1 1 1 -0.419577095333578 -2.62044249364659 4.14330720264433e-14 171.259674740177 40.3056973758615 4.24901901939903 2.53753017600646e-05 -547.513110034424 108.23001637618 -5.05879171385697 5.82865309053812e-07 CNOT6 other 4.13377759607825e-10 0.00747991051108757 0.221298006649523 4.24901901939903 -5.05879171385697 2.00771530498304e-33 201.853423591711 21.9245618788046 9.20672553036743 7.10837991219179e-19 -295.316795810716 51.4865678324085 -5.73580271988585 1.60739117339331e-08 TTC1 essential 2.83168166614808e-29 0.000218364090905482 9.65602327272132e-15 9.20672553036743 -5.73580271988585 1.5456113440468e-21 62.7699497549479 16.942400430506 3.70490297478308 0.000233089253245028 -280.580113203876 38.2962522662139 -7.32656843947657 8.575102398266e-13 MSH3 other 1.88610952314031e-17 1.2605400525451e-08 1 3.70490297478308 -7.32656843947657 0.00022268189074375 -0.501848068782785 19.7844944318635 -0.0253657262009457 0.979772567784358 -170.470263915657 44.7101945525731 -3.81278287025138 0.000153160872661543 RASGRF2 other 1 1 1 -0.0253657262009457 -3.81278287025138 0.467499127735835 -17.7780419744239 18.127780215702 -0.98070705640092 0.32717156613886 -45.2473317080059 43.0466366471452 -1.05112350771792 0.293666856901565 GABRG2 other 1 1 1 -0.98070705640092 -1.05112350771792 1.26458091202659e-19 48.5973695776175 55.3226948405469 0.878434604779949 0.380095016422912 -1155.68630264556 132.431003863256 -8.72670499303076 3.19715086337863e-17 CCNG1 other 1.48664132017846e-15 4.87117905544368e-13 1 0.878434604779949 -8.72670499303076 4.33263759458077e-11 3.50191682556106 5.28547653667583 0.662554606242468 0.507896451620454 78.978585035006 11.7559796807453 6.71816277161162 4.64958825341459e-11 POLR3G other 3.80665539059866e-07 6.6828531966328e-07 1 0.662554606242468 6.71816277161162 5.2330257557936e-22 304.795478648287 31.7378748231905 9.60352513664768 2.93322860851755e-20 -245.151628934271 145.507018681573 -1.68480964805388 0.0926063248600414 DROSHA other 6.44918094144003e-18 1 4.044335605424e-16 9.60352513664768 -1.68480964805388 7.86415323372721e-05 -18.5336267444112 5.2595636336831 -3.52379551522465 0.000461625863524428 -80.2324514011347 24.1209840728731 -3.32625116615228 0.000940308687166123 CDH6 other 0.433386565074953 1 1 -3.52379551522465 -3.32625116615228 0.00282709653652885 125.559769909006 78.3693715093582 1.60215358999036 0.10969998950367 623.210075098615 181.671152411265 3.43042947009991 0.000648203225978614 LMNB1 other 1 1 1 1.60215358999036 3.43042947009991 0.373837522458137 -20.4081588246182 100.931010851222 -0.202199092751592 0.839836536755132 -304.370777388688 224.46598002482 -1.3559773171642 0.175667933446732 ARRDC3 other 1 1 1 -0.202199092751592 -1.3559773171642 2.93602781593386e-18 504.228651758183 65.6245237913943 7.68353997296823 7.41724742973155e-14 -1024.67947945064 301.469064362647 -3.39895399090773 0.000726770384403495 GOLPH3 other 3.33496402225813e-14 1 9.26488376447768e-10 7.68353997296823 -3.39895399090773 0.000205102311278488 290.193716347223 196.28717459614 1.4784140479086 0.139883284204556 -3061.3722382129 890.935792036353 -3.43613116183797 0.000635768245079389 SUB1 other 1 1 1 1.4784140479086 -3.43613116183797 0.0113711500223071 139.816697114414 48.6677739801891 2.87288046441837 0.00422776774551818 322.746007042699 216.153067617014 1.49313637137248 0.135986602119356 NPR3 other 1 1 1 2.87288046441837 1.49313637137248 0.0187272633905266 0.481497294437464 14.4461082213487 0.0333305889073917 0.973423163912596 89.7655426748708 34.0651917160419 2.63511045007854 0.00865037530875192 SLC27A6 other 1 1 1 0.0333305889073917 2.63511045007854 1.25203715126866e-18 568.968598739289 60.3766496799679 9.42365304724857 1.26704588210417e-19 426.689842369558 271.711226751237 1.57037987524973 0.116912495930101 TARS essential 1.43458416792363e-14 1 1.73509263095346e-15 9.42365304724857 1.57037987524973 0.0236727585001047 22.7833984898249 8.29712300302922 2.7459395843001 0.006239590684455 14.7201487354018 38.3418633099983 0.383918450086469 0.701193443388697 IRX4 other 1 1 1 2.7459395843001 0.383918450086469 1.08226582961321e-22 231.980657185407 67.5957106103921 3.43188428808 0.000644809710956822 -1226.07491227291 156.377873962609 -7.84046285580065 2.3688906385334e-14 LNPEP other 1.34991016927656e-18 3.53556927801109e-10 1 3.43188428808 -7.84046285580065 0.132285732072507 14.5113345769775 34.7885739213036 0.417129331308726 0.676750825766614 -130.992884332314 80.9508913301615 -1.61817717112038 0.106212687763816 PDE4D other 1 1 1 0.417129331308726 -1.61817717112038 1.90461201533172e-25 159.164073224545 14.9517585078995 10.6451741539601 3.69022518345581e-24 -139.853600563104 70.43819759996 -1.98547954559222 0.0475946309499073 RAD1 other 2.47732884834197e-21 1 5.25709479635115e-20 10.6451741539601 -1.98547954559222 1.37180749308421e-30 254.792751354503 20.574253316242 12.3840582420243 3.42258274009973e-31 12.6272536351916 96.9259448509297 0.130277333428238 0.89639534863489 BRIX1 essential 1.88719556823595e-26 1 5.05447019057928e-27 12.3840582420243 0.130277333428238 0.00532095696210921 163.682761369984 282.485234646696 0.57943829019843 0.562534227104616 -4206.76101626097 1363.70329256933 -3.08480667252412 0.00214073504000039 PRLR other 1 1 1 0.57943829019843 -3.08480667252412 6.44433473237317e-12 384.098780384571 54.1356456696167 7.09511774790088 4.2065808323763e-12 -222.219708897852 248.242934664201 -0.89517032659338 0.371106269760487 SLC12A7 other 5.89721071359469e-08 1 5.04242844376947e-08 7.09511774790088 -0.89517032659338 3.56374178854749e-22 286.238692305268 64.3266437340526 4.44976880013626 1.04311560222115e-05 -1043.3059332102 150.71634749023 -6.92231433805038 1.25570990685496e-11 RAD50 other 4.40442847646585e-18 1.8215327908838e-07 0.0938804041999031 4.44976880013626 -6.92231433805038 0.109299327132873 -17.8875227558934 12.2670066315994 -1.45818155097558 0.145365464793816 22.4528073319014 27.3052838709205 0.822288002499516 0.411271949393143 ST8SIA4 other 1 1 1 -1.45818155097558 0.822288002499516 6.44525471003308e-11 123.620084547959 29.516060828102 4.18823112162249 3.27669950197238e-05 -256.291901948954 68.6071459324875 -3.73564442108052 0.000206891496802987 GNPDA1 other 5.61510590338082e-07 1 0.283303438940532 4.18823112162249 -3.73564442108052 2.49214822751144e-06 -29.9718366239886 15.8056743426857 -1.89627066673423 0.0584518883680122 -188.839525542519 36.7406954888843 -5.13979180387729 3.83675851925619e-07 PCDH12 other 0.0160519267334012 0.00495632465517514 1 -1.89627066673423 -5.13979180387729 3.48806621476815e-50 994.047320299726 127.88758642236 7.77282102280667 3.84872152281587e-14 -3177.90106199354 294.269930463955 -10.7992721410005 9.08344446744669e-25 SKP1 essential 5.27709537632274e-46 1.41392896580275e-20 4.8409219313978e-10 7.77282102280667 -10.7992721410005 4.66492466388325e-17 347.184168460826 38.6413126645338 8.98479229923993 4.39283661468663e-18 274.982244850117 198.356732763475 1.38630154378481 0.166230153174526 NUP155 essential 5.1346825775363e-13 1 5.91056166506086e-14 8.98479229923993 1.38630154378481 2.39952794711095e-45 453.094031537372 69.2598918987096 6.5419396293602 1.40107822010948e-10 -1718.06461982951 159.367333008099 -10.7805319157986 1.07453116191569e-24 PPP2CA essential 3.58729428093087e-41 1.67229284728938e-20 1.60661639499954e-06 6.5419396293602 -10.7805319157986 0.107835628068404 -16.8987706214043 24.3888357435431 -0.692889599122344 0.488672903894435 -119.824042041865 56.6894214890505 -2.11369315287525 0.0349935549330188 FGF1 other 1 1 1 -0.692889599122344 -2.11369315287525 0.00625264113216419 2.82135306206093 69.2886901008357 0.0407188107893946 0.967534977266977 -479.256267042533 160.911940094104 -2.97837604072299 0.00302679254454316 NR3C1 other 1 1 1 0.0407188107893946 -2.97837604072299 2.98483854486596e-29 159.419761562568 44.1879365384664 3.6077665999133 0.000337260828480986 -953.117406939525 101.676647251564 -9.37400507101072 1.84908720518318e-19 C5orf15 other 4.05639558247284e-25 2.84241685180758e-15 1 3.6077665999133 -9.37400507101072 4.44860440252849e-14 31.8443412605782 10.1197555876302 3.1467500360881 0.00174218441373406 -121.868662977788 22.4001762645646 -5.44052250028833 8.07273224281315e-08 PPWD1 essential 4.43258942667939e-10 0.00107213956916801 1 3.1467500360881 -5.44052250028833 0.0450685458108322 49.9998599183961 58.1901930096925 0.859248910036574 0.390587317156331 -598.042661715281 280.615676665734 -2.13118051286801 0.0335286343746413 LIFR other 1 1 1 0.859248910036574 -2.13118051286801 1.43848090737934e-27 43.2793849417014 11.6465339617221 3.71607424869449 0.00022347185450959 -222.086087874546 25.7797148710492 -8.61476121770261 7.77249381199121e-17 TRIM23 other 1.92109125180512e-23 1.18141905942266e-12 1 3.71607424869449 -8.61476121770261 1.01848214700109e-33 33.737310285779 7.09658303109841 4.75402177892325 2.56224245035083e-06 -145.359805965095 15.7083547518709 -9.25366203279709 5.07336347843072e-19 TRAPPC13 other 1.43972636300074e-29 7.78406158495625e-15 0.0240594566087943 4.75402177892325 -9.25366203279709 0.669510832368794 -8.66181058818209 10.088431734353 -0.858588412576263 0.390948576288739 -19.3839249767382 46.9971923203161 -0.412448574472795 0.680174358648842 C9 other 1 1 1 -0.858588412576263 -0.412448574472795 0.000186257864434058 110.717687714041 38.7595761381565 2.85652472873783 0.00444651230611647 -157.786412362282 89.5253396889893 -1.76247767291843 0.07854910576487 SEC24A other 0.976363725363334 1 1 2.85652472873783 -1.76247767291843 7.70413759239772e-29 109.794668610047 26.5675925880893 4.13265403126023 4.15156142476459e-05 -554.969923574936 61.4640461739271 -9.02917979080838 2.98816848356267e-18 TXNDC15 other 1.0429861472588e-24 4.57398949778937e-14 0.355332142345602 4.13265403126023 -9.02917979080838 0.0166638911831617 11.1680205573508 5.63903321490465 1.98048497530256 0.0481542359119967 -44.5872171088213 26.3672401544027 -1.69100811642497 0.0914101433045639 TTC33 other 1 1 1 1.98048497530256 -1.69100811642497 5.24420406164428e-21 217.360151462005 31.8593078698044 6.82250073825409 2.37871380807305e-11 -355.931995793045 81.1433762409022 -4.38645780200639 1.38251096438042e-05 RARS essential 6.33762060849711e-17 0.165569513094199 2.79142065377372e-07 6.82250073825409 -4.38645780200639 2.00958961875552e-05 74.6331671594568 48.2537892731176 1.54667992470045 0.122519836791611 -437.797848736594 123.339053674325 -3.54954765497548 0.00041917088629205 WWC1 other 0.118806938260826 1 1 1.54667992470045 -3.54954765497548 1.97672512643788e-20 769.201674566501 138.687798393326 5.54628225033183 4.55941723521897e-08 -1800.26884554691 320.853807733759 -5.61086950553118 3.20938856652122e-08 H2AFY other 2.36001212845418e-16 0.000431502292768777 0.000474361769152182 5.54628225033183 -5.61086950553118 0.00127715721121247 103.468990974034 29.6054591105777 3.49492945161137 0.000512634436148781 12.2249925655011 69.3124091972939 0.176375236513614 0.860064437733613 TCERG1 essential 1 1 1 3.49492945161137 0.176375236513614 0.513099504458991 -119.733520535829 182.191802960259 -0.657183905040701 0.511338584109206 282.275235281459 427.717462706214 0.659957237881928 0.509558546213236 DPYSL3 other 1 1 1 -0.657183905040701 0.659957237881928 2.85015447880132e-18 182.395432860325 48.6076806937804 3.75239942035876 0.000193933927126148 -738.241695563848 111.9045992523 -6.59706303848522 9.94272537997532e-11 SMAD5 other 3.23834551881406e-14 1.42180972933647e-06 1 3.75239942035876 -6.59706303848522 1.96016697801487e-32 691.576468778361 159.780786041259 4.3282830552591 1.78666098195575e-05 -3795.57561450293 380.835824055583 -9.96643533710466 1.29590882900849e-21 CSNK1A1 essential 2.74227360224281e-28 2.00541891289064e-17 0.157583498608497 4.3282830552591 -9.96643533710466 7.05374479229339e-15 133.886644765293 37.8323181938154 3.53894900332013 0.000436097532063249 -526.928821763297 89.7514029686948 -5.8709814480236 7.5413102537279e-09 HMGXB3 other 7.24983889751914e-11 0.000103496941922162 1 3.53894900332013 -5.8709814480236 9.27003902610043e-27 1316.71934926971 246.951820767757 5.33188759319981 1.43403071822905e-07 -5311.37025732499 683.641347335813 -7.76923496219719 4.03729812562734e-14 ERGIC1 other 1.22661156393361e-22 6.0127480984968e-10 0.00145037866841686 5.33188759319981 -7.76923496219719 0.00148047551490478 -265.871981408846 187.395328007336 -1.41877593340234 0.156538062626547 -1612.31523569726 444.584245428242 -3.62656853515852 0.000314279648377915 PDGFRB other 1 1 1 -1.41877593340234 -3.62656853515852 2.82148384830139e-29 588.086192942466 78.964091317143 7.44751421985645 3.81645574101377e-13 -1409.16880200817 218.59777187052 -6.4464005737572 2.55324140976875e-10 ATP6V0E1 other 3.83580729176575e-25 3.62330488460284e-06 4.6854627132426e-09 7.44751421985645 -6.4464005737572 1.27204879382451e-20 41.4692655702769 5.54656936679485 7.47656124496291 3.12532128234828e-13 -55.1633942117159 15.3546717866607 -3.59261304820847 0.000357467426587834 BNIP1 essential 1.52455047939868e-16 1 3.84820809495543e-09 7.47656124496291 -3.59261304820847 6.05030837368495e-06 1794.33482827788 1383.41667545557 1.29703137175717 0.195177378965476 -15421.5645760562 3829.73827443333 -4.02679333964097 6.46868707342942e-05 STC2 other 0.0374514088331098 0.739759053717388 1 1.29703137175717 -4.02679333964097 5.09456079181335e-15 88.5632804016442 49.3496670304569 1.79460745595276 0.0732775214167825 -953.180337593241 136.379496090665 -6.98917626854676 8.21595911164974e-12 CPEB4 other 5.26064347362647e-11 1.19410749728717e-07 1 1.79460745595276 -6.98917626854676 0.115697691544947 11.0413681807127 5.45025388267671 2.02584474382138 0.0432700786802511 17.9236586332021 15.2129573708899 1.17818371512032 0.239240394323462 HRH2 other 1 1 1 2.02584474382138 1.17818371512032 0.000471829875128338 340.438508692859 86.4394936441713 3.93846023779681 9.2796188543991e-05 372.783600286935 246.176283726855 1.51429534414679 0.130538193759041 DBN1 other 1 1 0.769094810652598 3.93846023779681 1.51429534414679 2.80939791839065e-23 35.8219138044528 6.12942617430994 5.84425242848865 8.82482229628209e-09 -112.257387212192 17.5384105708475 -6.40065909956444 3.37077351969922e-10 ZNF346 other 3.53506540071095e-19 4.77031868507834e-06 9.46373943053291e-05 5.84425242848865 -6.40065909956444 0.000642247737644024 38.5176750891222 21.9330319321599 1.75614913652885 0.0796319045224988 -163.136772110669 62.5016465192688 -2.61011959197547 0.00930323480652109 UNC5A other 1 1 1 1.75614913652885 -2.61011959197547 1.2223335580492e-08 57.5570887023828 9.37924405761957 6.13664473904207 1.6264150167128e-09 11.5159994359112 38.8696619131693 0.296272179100418 0.767135507977461 EHHADH other 9.4034120620725e-05 1 1.79377312193255e-05 6.13664473904207 0.296272179100418 8.91100710995178e-05 16.0678300839977 9.20279253357094 1.74597330379705 0.0813780191546678 -52.213373142275 18.3401887968504 -2.84693760356719 0.00458028000331338 CNTN3 other 0.487253868772163 1 1 1.74597330379705 -2.84693760356719 2.93200210969422e-12 664.50263619567 89.331797827515 7.4385902036665 4.06737519602637e-13 -136.991498258682 336.240728384615 -0.407420894300413 0.683861548071087 SMC4 essential 2.72207075864011e-08 1 4.98822894040674e-09 7.4385902036665 -0.407420894300413 4.39240627777491e-16 103.204174956137 25.1652589237424 4.10105754400832 4.74154040649337e-05 -222.375708927356 46.8619054280254 -4.74534073884171 2.66405735920334e-06 SELENOK other 4.69416458905805e-12 0.0331808344088776 0.403505088592586 4.10105754400832 -4.74534073884171 1.0440135146431e-32 37.1190495730269 13.5481894671766 2.73977933826182 0.00635138284032369 -248.215488035582 25.2285870172589 -9.83865992438568 4.0353285121445e-21 ACTR8 essential 1.46464655969281e-28 6.2357931498169e-17 1 2.73977933826182 -9.83865992438568 3.58866718873653e-31 70.5795519421305 5.58999914527855 12.6260398450586 3.12341392354499e-32 19.9976459513549 22.6399428661271 0.883290477789787 0.377469516702789 TBCCD1 other 4.96635652249249e-27 1 4.6273377277319e-28 12.6260398450586 0.883290477789787 5.90270851302059e-28 282.090806568395 25.0527812490568 11.2598598839806 1.4248136769083e-26 -153.353847989421 79.6371322942206 -1.92565758675053 0.0546699508799131 TIMMDC1 other 7.91494184510931e-24 1 2.05985313270633e-22 11.2598598839806 -1.92565758675053 7.54914588503828e-21 118.506338112589 18.4707203504625 6.41590235053403 3.11567435416635e-10 -305.124400785061 46.3597741922616 -6.58166279066976 1.12351776548045e-10 CRBN other 9.09747570605963e-17 1.60438336910608e-06 3.53660195941423e-06 6.41590235053403 -6.58166279066976 0.253324530912206 16.9455090209575 53.449446914478 0.3170380611809 0.751337256497649 -368.082081389715 225.96456383095 -1.62893718886421 0.103909517107266 BCL6 og 1 1 1 0.3170380611809 -1.62893718886421 0.0521224048450094 55.1117389631439 25.1557924232039 2.19081705064112 0.0288885522181436 -55.949564324065 80.8575953824434 -0.691951869944099 0.489262775077524 HGD other 1 1 1 2.19081705064112 -0.691951869944099 9.19560041637222e-09 24.2901875739613 5.878519165467 4.13202490121195 4.18306615900826e-05 -78.5428978383211 19.8118898976414 -3.96443238096491 8.37447137197547e-05 ARL6 other 7.12750988273011e-05 0.9491625852997 0.357861309903157 4.13202490121195 -3.96443238096491 0.0434686417413175 7.21094507980528 11.6102361388152 0.621085135012691 0.534802800156561 -91.4442320999468 39.8843367716365 -2.29273543204501 0.022242591272151 NPHP3 other 1 1 1 0.621085135012691 -2.29273543204501 0.00638509729089641 19.8036875817238 11.3103326946481 1.75093767056867 0.0805161546352507 108.999551658788 36.9633467946516 2.94885504454806 0.00332561801929817 CD86 other 1 1 1 1.75093767056867 2.94885504454806 0.164565801800217 9.54799568039825 63.1816774791932 0.151119692628335 0.879937319067484 -411.045862527318 223.081464798441 -1.84258186980576 0.0659340398339766 AMOTL2 other 1 1 1 0.151119692628335 -1.84258186980576 1.52947895389377e-18 223.530247251473 27.6521328248462 8.08365302840674 4.08320833503362e-15 -362.475394084831 97.2152079613897 -3.72858734436687 0.000212698311795155 NIT2 other 1.74895918377752e-14 1 5.22977323551107e-11 8.08365302840674 -3.72858734436687 5.91394180995382e-08 166.952627814028 50.9678454844825 3.27564616920796 0.00112108550149167 -701.851953956869 167.167552082916 -4.19849393744037 3.13700432887783e-05 FAM162A other 0.000435680093139298 0.36640210561293 1 3.27564616920796 -4.19849393744037 7.26880853642691e-33 160.985524036735 12.9113703774522 12.4685079376139 1.57338338861671e-31 -80.7350072113751 38.9244229245457 -2.07414782661977 0.0385397436910797 OGG1 other 1.02119491128262e-28 1 2.32593266339209e-27 12.4685079376139 -2.07414782661977 2.74779596590335e-24 357.623472327492 39.318779061426 9.09548772531296 1.75328451419033e-18 -567.83809955027 129.156192626949 -4.39652244310421 1.32292532687503e-05 KPNA1 other 3.51305714240743e-20 0.158631975945585 2.37044066318533e-14 9.09548772531296 -4.39652244310421 1.61012977348913e-16 230.64122233756 34.8235584725059 6.62313768191316 8.47274492694287e-11 -571.543808421819 123.255864905908 -4.63705162312666 4.43249717553361e-06 PCCB other 1.74216041491524e-12 0.054599500208223 9.77924219467746e-07 6.62313768191316 -4.63705162312666 1.05883313861687e-27 288.490300715158 83.2942684854532 3.46350722517649 0.000576062601720599 -1319.47947508759 155.838847209958 -8.46694838104065 2.45491373600453e-16 UBE3A other 1.4166128561555e-23 3.71943980142047e-12 1 3.46350722517649 -8.46694838104065 6.24792288839769e-27 166.82555026172 14.8847269264789 11.2078341165231 2.18281477136665e-26 -105.635834723488 54.4924311820632 -1.93854141634002 0.0530712776294304 ARMC8 other 8.28412095772649e-23 1 3.15220281133057e-22 11.2078341165231 -1.93854141634002 5.21468689010361e-16 123.078634998565 14.6379469394813 8.40818972137403 3.642618310163e-16 -67.4259809413424 53.588469949405 -1.25821806453892 0.208850684833488 CEP70 other 5.55989916222847e-12 1 4.75580246574881e-12 8.40818972137403 -1.25821806453892 0.989034488805946 5.08463037479048 123.511100205064 0.0411673960182409 0.967177522469879 67.6948493629032 462.372374451832 0.146407642634704 0.883653732372074 RBP1 other 1 1 1 0.0411673960182409 0.146407642634704 8.08804581949766e-09 190.169909216698 35.0372288390503 5.4276526859552 8.60003522862237e-08 -334.893346572777 131.907850410176 -2.53884318129212 0.011398450747042 SLC25A36 other 6.29007323382333e-05 1 0.000882105613399796 5.4276526859552 -2.53884318129212 1.94894418695779e-11 166.12592430088 27.1426419001393 6.12047732538619 1.7844460824339e-09 -328.297527126472 101.155994860619 -3.24545794422592 0.00124458593352173 RNF7 other 1.74157652546548e-07 1 1.96556735980094e-05 6.12047732538619 -3.24545794422592 2.72157126460133e-08 145.917506737656 31.4618448618487 4.63791959366627 4.41105794286729e-06 -363.676333650517 113.54688858333 -3.20287361624727 0.00144008532066615 TFDP2 other 0.000205206473350941 1 0.0407361201023795 4.63791959366627 -3.20287361624727 6.44711074665242e-10 181.279943120984 29.8719877991456 6.06855976039763 2.41524328107218e-09 -205.909295242597 107.656367933731 -1.91265318712355 0.0563153356595999 XRN1 other 5.33229241747594e-06 1 2.64589901441457e-05 6.06855976039763 -1.91265318712355 0.162648380782789 34.0863782219575 18.9672080915801 1.79712154036466 0.0728770390881507 -2.43701926173698 43.0944351192484 -0.0565506719137496 0.954924125236507 KAT2B other 1 1 1 1.79712154036466 -0.0565506719137496 0.846263640380392 86.0732980681879 194.929045461827 0.441562199539133 0.658984452747226 -288.429723090055 784.112693265472 -0.367842180808063 0.713136396003432 BCHE other 1 1 1 0.441562199539133 -0.367842180808063 3.43289816989692e-24 221.557261019563 20.5046031620504 10.8052450110138 9.091959921156e-25 -130.421655468485 83.8670820728882 -1.55509947699309 0.120509321820252 PDCD10 other 4.38209451387342e-20 1 1.30024118832452e-20 10.8052450110138 -1.55509947699309 0.750828154894638 -3.22919326770234 21.188517729426 -0.152402981130564 0.878926563164093 -67.8818490159269 91.7519092191733 -0.739841269719778 0.45972083164741 LRRC31 other 1 1 1 -0.152402981130564 -0.739841269719778 0.00250299329090629 -50.8883144918034 71.4114850966932 -0.712606864608672 0.476395720311718 -443.302869326209 133.077304470413 -3.3311680837717 0.000923740842626897 WNT5A ts 1 1 1 -0.712606864608672 -3.3311680837717 6.89836922988997e-10 60.0867678699752 12.736544279421 4.71766646837322 3.07572253032477e-06 -41.6267849955364 22.9976100576555 -1.8100483002876 0.070869919181287 PFKFB4 other 5.69460379927417e-06 1 0.0287118698205817 4.71766646837322 -1.8100483002876 0.063219765077884 28.8646513871144 12.5620353773404 2.29776867522448 0.0219563790618545 -29.7457661833555 55.7440799877335 -0.533613007693393 0.59382887493048 FGF12 other 1 1 1 2.29776867522448 -0.533613007693393 8.03848660833832e-21 291.60831605719 56.4215094476955 5.16838912875098 3.36120624028197e-07 -525.964652864076 102.045930931804 -5.15419525366053 3.61272713450309e-07 PRKAR2A other 9.68155327108267e-17 0.00467306254847975 0.00333364434911166 5.16838912875098 -5.15419525366053 0.0459458003251978 -35.4953983834321 42.9777691979941 -0.82590136821454 0.409220772505296 -466.447370206577 201.341910419925 -2.31669287945932 0.0208896609577478 HES1 other 1 1 1 -0.82590136821454 -2.31669287945932 2.15712180046504e-32 165.911498347881 33.0935567080477 5.01340789119637 7.33712816153005e-07 -487.121081831644 59.8911265443908 -8.13344329849254 3.06269829940727e-15 USP4 other 3.01673483795036e-28 4.60936094060794e-11 0.00711994916794876 5.01340789119637 -8.13344329849254 2.86326917428618e-19 257.485704455919 26.8171543919492 9.60152970343562 2.82530290741883e-20 -96.3965338043277 127.096064353373 -0.75845412125674 0.448506427777632 ACAP2 other 3.33656756879568e-15 1 3.89609270933056e-16 9.60152970343562 -0.75845412125674 1.06381467671569e-19 490.789937746693 50.3712606864708 9.74345154475186 9.39154811338837e-21 112.938324800139 212.895390218872 0.530487413015521 0.595994976402166 ECT2 essential 1.25253540036505e-15 1 1.30044766726089e-16 9.74345154475186 0.530487413015521 9.75500832765318e-12 199.205224534571 162.627188013868 1.22491956583289 0.22115587147056 -1712.02558167484 299.648058563878 -5.71345461031872 1.85848191338926e-08 GNAI2 other 8.8458415515159e-08 0.000251880053721646 1 1.22491956583289 -5.71345461031872 9.27452759063065e-15 491.339067713039 64.101379532232 7.66503110071102 8.29109206927622e-14 -476.798579440614 225.255957502204 -2.11669686665645 0.0347398086069112 TFG other 9.48320446141984e-11 1 1.03423082472152e-09 7.66503110071102 -2.11669686665645 0.010201570185817 35.7428603704843 12.4953264466902 2.86049832495188 0.00439791155878816 10.7493299254967 22.9378875554789 0.468627719073855 0.639529907817145 HYAL1 other 1 1 1 2.86049832495188 0.468627719073855 1.43011240181738e-45 114.446915460922 21.465466865868 5.33167604394866 1.44799760424375e-07 -417.354984806011 39.4774729306555 -10.5719782403276 8.17845989692969e-24 TUSC2 other 2.13916213063844e-41 1.27109623718081e-19 0.00146421517741128 5.33167604394866 -10.5719782403276 7.19073104720819e-41 56.4927703230119 17.9237927985212 3.1518312534651 0.00171513896559756 -371.168298863255 32.958018422606 -11.2618511860734 1.68050275000222e-26 NPRL2 other 1.05696555662913e-36 2.62175234027847e-22 1 3.1518312534651 -11.2618511860734 1.58808080942732e-05 498.41325971948 173.605527267932 2.87095271425466 0.00425414789769417 -2076.3136064677 609.656921216012 -3.40570825034894 0.000709401281211953 RPL24 essential 0.0948878283632822 1 1 2.87095271425466 -3.40570825034894 8.37036224972469e-40 27.123266921904 17.0647107016564 1.58943608222266 0.112563959555262 -377.293429699458 31.3783503304076 -12.0240046314301 1.38290953581583e-29 CYB561D2 other 1.22500251524721e-35 2.16314709592312e-25 1 1.58943608222266 -12.0240046314301 1.09948100647014e-11 146.987149559161 36.5956687969455 4.01651764788706 6.75514882385749e-05 -241.847647341568 69.9599052229705 -3.45694646913501 0.000589952716053596 C3orf14 other 9.94150726050304e-08 1 0.567027192274598 4.01651764788706 -3.45694646913501 3.67500395872634e-22 597.497633615862 57.5751512908971 10.3776997579567 4.15018079288104e-23 -227.150379069819 220.669670669293 -1.0293683693861 0.303772617732307 FXR1 other 4.54083489140227e-18 1 5.8646204784202e-19 10.3776997579567 -1.0293683693861 7.57899167622263e-05 62.321521431722 18.0703392444725 3.44882963117505 0.000607146172785121 -143.005154560798 62.5517908359 -2.28618801555917 0.0226310790272645 CBLB other 0.418746177142477 1 1 3.44882963117505 -2.28618801555917 0.00305322608536849 110.456160027224 61.3013424930617 1.80185548203493 0.0721267805301626 -560.901589586397 210.397789799508 -2.66591008451606 0.00790845143781899 BBX other 1 1 1 1.80185548203493 -2.66591008451606 2.12399841386785e-08 82.1469570003505 18.7662702393632 4.37737259202647 1.44313108314198e-05 -229.735339337301 63.9342477963235 -3.59330636170419 0.000356425032069994 IFT57 other 0.000161190239628431 1 0.128366509845479 4.37737259202647 -3.59330636170419 4.23019790331653e-08 464.32563930109 78.6337295978414 5.90491690621573 6.30116020070938e-09 109.997145528155 322.290176412459 0.341298474413888 0.733013906299526 GNB4 other 0.000314388308174484 1 6.79895185656542e-05 5.90491690621573 0.341298474413888 7.17626253272569e-10 122.215693326985 18.5114249160168 6.60217643328143 9.92027190176787e-11 37.965526459292 80.0382411593749 0.47434233822922 0.635452656320483 IQCG other 5.92185184200524e-06 1 1.14291452580268e-06 6.60217643328143 0.47434233822922 0.00138466467780755 152.677204536541 45.4185645548553 3.36155944233204 0.000832851436755979 11.0829237063971 90.5398293692604 0.122409372577853 0.90262275362095 GBE1 other 1 1 1 3.36155944233204 0.122409372577853 3.15870303237449e-20 158.376214465141 18.4648202849481 8.57718688950595 1.00791398497206e-16 -173.484151365268 58.5539069308303 -2.96281086025915 0.00318128113519083 UMPS essential 3.75664551640299e-16 1 1.32853142359168e-12 8.57718688950595 -2.96281086025915 3.99843071108453e-41 521.104250359178 35.1058182048697 14.8438144161213 5.43058097206885e-42 -185.173632406136 155.288458103675 -1.19244942391346 0.233613687514253 NCBP2 essential 5.88329094828977e-37 1 8.23764827653124e-38 14.8438144161213 -1.19244942391346 3.78720846885412e-17 162.597527284128 21.2736263296076 7.64315047960737 9.64298773124123e-14 -212.880122328481 67.5656596312191 -3.15071477863761 0.00171829188325901 SNX4 other 4.1795632662274e-13 1 1.20084126217147e-09 7.64315047960737 -3.15071477863761 0.000134723114129605 -49.9873052005686 24.338085403243 -2.05387171473677 0.0404646125337274 -325.667136168084 81.6307320730129 -3.98951629977785 7.52552535201794e-05 C3orf52 other 0.720364491250997 0.856103764045561 1 -2.05387171473677 -3.98951629977785 3.13543229701144e-10 -0.377576960212636 23.3107670897845 -0.0161975347597249 0.98708284070213 -276.042201673331 45.6706180258069 -6.04419676382195 2.81732467535959e-09 FRMD4B other 2.63877982116483e-06 3.9065023948536e-05 1 -0.0161975347597249 -6.04419676382195 2.70387840776681e-09 144.027692122736 26.6579830575244 5.40279779651532 9.84001251534029e-08 -201.110942322242 85.8055677198901 -2.34379828333242 0.0194488251946354 SLC41A3 other 2.16310272621345e-05 1 0.00100545247881747 5.40279779651532 -2.34379828333242 0.00105938836497097 98.3163547293056 27.3154257093679 3.5992979122997 0.000348224544929081 142.346266172592 87.9555274749266 1.6183890911594 0.106158376130565 ROPN1B other 1 1 1 3.5992979122997 1.6183890911594 0.00243675543887347 183.631655494103 54.7819786919248 3.35204495855808 0.000858344612722269 -39.9668895238606 172.381541546851 -0.231851329122719 0.816741321259371 PLXNA1 other 1 1 1 3.35204495855808 -0.231851329122719 6.7539101774357e-11 348.28001561517 68.7754461899447 5.06401680991334 5.6387582598773e-07 -901.592605259744 229.21678504346 -3.93336205762069 9.46674118778293e-05 ATP6V1A essential 5.87860341844004e-07 1 0.00550681131659617 5.06401680991334 -3.93336205762069 0.00622457606234311 8.87158691917596 22.8066027172066 0.38899204012015 0.69743738587751 -220.739739464829 72.9830964513391 -3.02453239445665 0.00261020706038237 ABTB1 other 1 1 1 0.38899204012015 -3.02453239445665 3.90547381396446e-09 398.368052943443 64.6275810976086 6.16405637001604 1.39875064523504e-09 -28.3187951975331 206.849070620852 -0.136905595526898 0.89115701610322 PODXL2 other 3.098212376618e-05 1 1.54757771388804e-05 6.16405637001604 -0.136905595526898 0.00371195697797004 29.0300884533947 8.63877785732062 3.36043928121085 0.000835477468299556 28.677775195833 15.9510619780894 1.79785993153467 0.0727802830551604 CSPG5 other 1 1 1 3.36043928121085 1.79785993153467 1.07861280813046e-24 27.671613796583 11.2302881854701 2.46401635822534 0.0140596042476382 -169.118026763899 20.7456681980262 -8.15196816750352 2.66431645577923e-15 KLHL18 other 1.38806682278309e-20 4.01166128746678e-11 1 2.46401635822534 -8.15196816750352 3.7416560067628e-26 179.7981741675 52.5507567983742 3.42141931194915 0.000671884918533435 -757.90442910499 97.4579716903557 -7.77673099449484 4.01138654143581e-14 SCAP essential 4.91242017127887e-22 5.9745591148145e-10 1 3.42141931194915 -7.77673099449484 0.00645571043511546 -5.03767024860453 15.8894188412812 -0.317045594865717 0.751331543271788 -167.886164527922 52.8486793891894 -3.1767333917953 0.00157456119591561 EFCC1 other 1 1 1 -0.317045594865717 -3.1767333917953 4.51305182802681e-13 21.9902520399116 3.57463691754962 6.15174423224659 1.49505274064175e-09 -41.5981686366776 11.9543943272351 -3.47973870511419 0.000542530630599223 KIAA1257 other 4.31853929423886e-09 1 1.65113624676475e-05 6.15174423224659 -3.47973870511419 1.56780138817549e-09 18.3219918613151 14.1916893749508 1.29103670304781 0.197239303152451 -292.340374750215 48.600563251694 -6.01516433536447 3.30085650269347e-09 NEK11 other 1.27070302511624e-05 4.56871548537803e-05 1 1.29103670304781 -6.01516433536447 4.31395999106377e-25 409.106190566706 38.2589454184654 10.6930859199599 2.34770641495809e-24 -157.528515651087 130.441539515407 -1.20765605984343 0.22770339883894 MRPL3 essential 5.57751887244634e-21 1 3.34782934773023e-20 10.6930859199599 -1.20765605984343 0.159811563436784 -37.1034166999047 23.6047664181788 -1.57186120983303 0.11656629227541 -104.592051414211 86.6437703401168 -1.20715027755185 0.227900825096216 PLSCR4 other 1 1 1 -1.57186120983303 -1.20715027755185 1.93963600355705e-41 62.8764243181063 26.2537139111283 2.39495351137556 0.0169726362983436 -561.559287236832 47.9166732832515 -11.7194965501313 2.46970029074197e-28 HEMK1 other 2.8576657240406e-37 3.8591536743134e-24 1 2.39495351137556 -11.7194965501313 2.91490985567353e-23 -14.2934833884345 82.3218969691023 -0.173629179048185 0.862223824076911 -1411.43554409817 150.209237617692 -9.39646300376357 1.72433975969418e-19 CISH other 3.66666510745173e-19 2.65099994655382e-15 1 -0.173629179048185 -9.39646300376357 4.91816632319274e-27 99.8948553627278 34.1092731595811 2.92867147579977 0.00355172938085906 -523.006142911468 62.486069639867 -8.36996383235125 5.23463294568778e-16 MAPKAPK3 other 6.52935761067068e-23 7.91633540376363e-12 1 2.92867147579977 -8.36996383235125 3.66774255856862e-14 35.8746067448065 17.8718221813789 2.00732786957701 0.0452070778768023 -222.764010817077 35.5351691839629 -6.268832143836 7.39375094838443e-10 ACVR2B other 3.66847610708034e-10 1.03911775828595e-05 1 2.00732786957701 -6.268832143836 1.22841822103658e-25 95.3628863679637 28.423404886396 3.35508313480086 0.000848746350723617 -461.599246295827 55.4705222657726 -8.32152335044176 7.0377765790809e-16 WDR48 other 1.60136599294328e-21 1.0636191743965e-11 1 3.35508313480086 -8.32152335044176 2.73647856113368e-24 247.696627833127 22.6406994602569 10.9403257734121 2.54964192586824e-25 4.65053985267081 88.8681440588538 0.052330786266797 0.958284297955061 COMMD2 other 3.49886148826552e-20 1 3.65822623523575e-21 10.9403257734121 0.052330786266797 2.36599044487886e-37 82.8524918335089 24.338952447164 3.40411083892655 0.000712727277807937 -516.759083761546 47.4993903454604 -10.8792782392192 4.46523438784019e-25 GORASP1 other 3.42240517851727e-33 6.95236994186717e-21 1 3.40411083892655 -10.8792782392192 0.594586903848731 -2.25278329486567 42.7132262122643 -0.0527420542683995 0.957957229360115 -174.483647912543 171.28908861951 -1.01865010386113 0.308832121931452 PEX5L other 1 1 1 -0.0527420542683995 -1.01865010386113 2.13017526103479e-09 72.9543136667735 17.2512065872291 4.22893977287252 2.7788453292987e-05 -70.5037621588847 31.5851401797985 -2.23218139155127 0.0260322345019295 RRP9 essential 1.71628220781573e-05 1 0.241481659116057 4.22893977287252 -2.23218139155127 0.000480451989719008 279.969543839314 76.3644366696873 3.6662294131798 0.000270215855150491 -522.773084137412 335.394598463491 -1.55868068994653 0.119651385930163 ABCC5 other 1 1 1 3.6662294131798 -1.55868068994653 1.35777890368416e-28 195.592101740705 65.4636765967231 2.98779585732122 0.00294268272286463 -1049.96863422211 119.682039368675 -8.77298414833763 2.49587070639162e-17 ABHD14B other 1.83313729786398e-24 3.80445571775275e-13 1 2.98779585732122 -8.77298414833763 2.68219455153949e-26 73.9554920471413 16.7903569004725 4.40464085936494 1.27555980709954e-05 -246.908149855086 32.3573451899423 -7.63066773264925 1.04708683546805e-13 EIF1B other 3.52762227418473e-22 1.55450511593586e-09 0.113945757568202 4.40464085936494 -7.63066773264925 5.22971595084139e-27 105.215366357136 45.9486106882797 2.28984869794929 0.0224297404330242 -747.630069467772 84.0041946804723 -8.89991353778869 9.29903371715213e-18 ABHD14A-ACY1 other 6.93878712357636e-23 1.42052039063216e-13 1 2.28984869794929 -8.89991353778869 0.0972686276055176 53.4025342753912 25.1200429137378 2.12589343333431 0.0339602482221991 -27.72974259641 101.884518086258 -0.272168363920937 0.785595454935878 ARHGEF26 other 1 1 1 2.12589343333431 -0.272168363920937 1.59867625296179e-17 311.920601085072 34.2657456584607 9.10298594386651 1.66762111343857e-18 -143.784260965966 146.885653996297 -0.978885664147913 0.328072391194954 KLHL24 other 1.78060561054884e-13 1 2.25545755592567e-14 9.10298594386651 -0.978885664147913 4.30323294457562e-17 194.55979561519 22.6247511610759 8.5994225629281 8.60207519363721e-17 257.268011383541 87.001943752649 2.95703751303496 0.00324123689363813 PLCH1 other 4.74173238162788e-13 1 1.13573198781592e-12 8.5994225629281 2.95703751303496 5.82872612740579e-17 18.2102580347254 22.6823742620358 0.802837384850159 0.422418057593395 -330.835812477366 43.7393432241031 -7.56380384548286 1.67047137232374e-13 VIPR1 other 6.39352968915141e-13 2.47430219668592e-09 1 0.802837384850159 -7.56380384548286 5.30597470442677e-09 14.5566065902271 8.75311735276607 1.6630196995619 0.0969064498152674 -70.7527359759464 15.9080001129402 -4.4476197808418 1.06083683286208e-05 DNAH1 other 4.1736797025021e-05 0.127883880201524 1 1.6630196995619 -4.4476197808418 1.27259149939045e-07 507.549887513606 90.636177495349 5.59985980807334 3.41660087500262e-08 -328.669926642619 347.976352377203 -0.944517994965197 0.345326636625749 SSR3 other 0.000914356992312041 1 0.000357478949551524 5.59985980807334 -0.944517994965197 1.9838794059815e-08 17.1949051026755 15.6938086253038 1.09564896024993 0.273714588025347 -143.68588467123 30.0690902499499 -4.77852450728766 2.27191198503793e-06 ZBTB47 other 0.000150854190030834 0.0283829964290789 1 1.09564896024993 -4.77852450728766 0.316350918438581 182.758579230365 281.666935752956 0.648846406987074 0.51671870203771 780.364977076802 515.139825590631 1.51486050643061 0.130403861772053 TNNC1 other 1 1 1 0.648846406987074 1.51486050643061 1.19142477929502e-16 47.6572090378757 59.1627853241055 0.805526798253328 0.420866407678771 -850.684856074929 114.007044578817 -7.4616867687226 3.38815093655982e-13 NKTR other 1.29567444748333e-12 5.00294367292422e-09 1 0.805526798253328 -7.4616867687226 3.58373938102903e-12 44.162580803778 6.01446440072037 7.34272877207296 8.04940294923935e-13 -41.6401609488232 26.8048979918002 -1.55345343830673 0.12091858308164 CLCN2 other 3.31352543169944e-08 1 9.80095303099383e-09 7.34272877207296 -1.55345343830673 1.92080164184763e-12 -86.270366122912 89.0608593326571 -0.968667569225644 0.333144725289292 -1238.15754871559 173.497947654904 -7.13643916513839 3.10127915287209e-12 FOXP1 other 1.79575745496335e-08 4.53313973775313e-08 1 -0.968667569225644 -7.13643916513839 3.41296493889807e-34 2174.58902963048 163.138103348541 13.3297432359166 3.52050854661792e-35 280.898497511779 717.192868793441 0.391663818387297 0.695463459503209 EIF4G1 essential 4.84163206232081e-30 1 5.26316027719379e-31 13.3297432359166 0.391663818387297 3.15931127090146e-53 287.551417959878 60.2581691035374 4.7719906236414 2.35669349773047e-06 -1351.52621993429 109.462257995344 -12.3469609040203 5.43120948194922e-31 SPCS1 other 4.80626023642239e-49 8.5020153230433e-27 0.0221891443919706 4.7719906236414 -12.3469609040203 3.86152660881095e-37 82.6413593567527 22.8858796376709 3.61101957473911 0.000333698390905446 -424.360246586365 41.7565529617552 -10.1627221714167 2.64804936093346e-22 NEK4 other 5.5783613390883e-33 4.10527092425514e-18 1 3.61101957473911 -10.1627221714167 0.00189743035356139 53.3252643228038 15.411126663958 3.46017948496364 0.000582173918307479 0.850640574286744 34.1135599218908 0.0249355557213741 0.980115510655988 SLC4A3 other 1 1 1 3.46017948496364 0.0249355557213741 6.39602634267647e-08 38.3814162269544 18.3829922364227 2.08787643128676 0.0372710036989236 -207.090776815413 44.1401686031542 -4.69166256878807 3.42805547886244e-06 INO80D other 0.00046953229381588 0.0424461829392747 1 2.08787643128676 -4.69166256878807 0.0210312487377214 117.738306416975 84.2885654115538 1.39684790982142 0.163026785880061 -391.016685636973 200.725309522192 -1.94801884509608 0.0519247506568707 EEF1B2 essential 1 1 1 1.39684790982142 -1.94801884509608 0.0763205730708849 -12.8973721185723 5.88989936479689 -2.18974405499322 0.0289659845589507 -16.6196538809689 14.0943057492169 -1.17917506379428 0.238842984450343 ADAM23 other 1 1 1 -2.18974405499322 -1.17917506379428 2.64742478984601e-11 170.132822744901 26.1747404081107 6.49988577125229 1.82247236043937e-10 -168.952523033643 88.7974323964526 -1.9026735173977 0.0576118529335595 DGUOK other 2.35144269834123e-07 1 2.08253916627406e-06 6.49988577125229 -1.9026735173977 3.08701143542637e-06 366.958551999411 82.2332790972792 4.46240933144976 9.86164608847729e-06 -486.585096333265 280.201217350485 -1.73655596836551 0.0830337644255855 MOB1A other 0.0196982199694557 1 0.0889421860719766 4.46240933144976 -1.73655596836551 7.13928988437249e-07 13.4622825242703 48.5168852009932 0.277476232624982 0.781524730403599 -957.128472387705 182.481810506698 -5.24506234199477 2.27750390749028e-07 KANSL3 essential 0.00482972960677799 0.00296599333872459 1 0.277476232624982 -5.24506234199477 3.9996086895023e-08 89.2335612371207 21.8503756984782 4.08384562666057 5.12799994221227e-05 -286.54601848906 82.1836789643748 -3.48665358012596 0.000530494585542669 LMAN2L other 0.000297930851281027 1 0.435008235097867 4.08384562666057 -3.48665358012596 5.19675928953541e-09 214.956347994527 36.3063607294235 5.92062502756774 5.70798100533922e-09 -151.281078392038 124.21950073807 -1.21785289341188 0.223811749528969 RTKN other 4.08984956086437e-05 1 6.16918587057063e-05 5.92062502756774 -1.21785289341188 1.76274735588863e-06 156.053614841528 29.9483925708548 5.21075094338774 2.67243652163711e-07 87.0373879005902 79.1728101538925 1.09933432615832 0.272107640127043 TTL other 0.0115142657286645 1 0.0026644192120722 5.21075094338774 1.09933432615832 0.208046465376207 15.0671900261033 8.69390315884313 1.73307543813361 0.0836531303375278 15.2454276360981 17.9399127843895 0.84980500291863 0.395810113086907 CCL20 other 1 1 1 1.73307543813361 0.84980500291863 1.72396003688924e-05 68.850576153096 28.1151856361554 2.44887503301974 0.0146442513210067 -213.412258896365 66.4991434610366 -3.20924823672966 0.00140911734129717 PIKFYVE other 0.102627340996016 1 1 2.44887503301974 -3.20924823672966 0.492150137316138 8.01071108568231 8.24662155058762 0.971393077339835 0.331826036901414 27.3395291094967 31.6084997291662 0.864942320697038 0.387488574839632 KCNIP3 other 1 1 1 0.971393077339835 0.864942320697038 4.19194710013273e-11 85.9563144409174 12.1523496029595 7.07322593977909 4.95327965867941e-12 78.6384086270872 49.7985220282961 1.57913137627667 0.114918717394269 FAHD2A other 3.68807505869678e-07 1 5.92560845567818e-08 7.07322593977909 1.57913137627667 3.0833141831215e-08 2322.20521192567 400.973836864717 5.79141330038736 1.18352679053972e-08 350.112521505019 815.792580132757 0.429168553418375 0.667971102136597 NCL essential 0.000231556895152424 1 0.000126341484890115 5.79141330038736 0.429168553418375 1.50893054735555e-17 195.314162469506 26.6223399338821 7.33647616830747 8.03506476897722e-13 -396.712008145118 97.8943875127452 -4.05244895263754 5.80861497868802e-05 ACTR1B other 1.68245756030144e-13 0.666712827253811 9.78429836918357e-09 7.33647616830747 -4.05244895263754 7.60539639937677e-07 78.3578886452143 42.8866523849601 1.82709268006876 0.0682335671672766 -511.83254906492 113.658130778038 -4.50326382777201 8.1929745147976e-06 SLC35F5 other 0.00513592418849913 0.0994627106096428 1 1.82709268006876 -4.50326382777201 0.58227341957522 5.73754180058029 6.93991428223239 0.82674534111604 0.408744554856059 -11.7693262895831 24.8199133008519 -0.474188855815994 0.635555859616652 ZAP70 other 1 1 1 0.82674534111604 -0.474188855815994 2.98160418264696e-10 960.591054257975 146.088177928839 6.57541950263688 1.13961881598483e-10 -1.310564207127 380.949910515965 -0.00344025335339219 0.997256341550049 ACTR3 other 2.51229968429833e-06 1 1.31113144779054e-06 6.57541950263688 -0.00344025335339219 0.0011483463672711 344.844517184941 93.1400483358671 3.70243008615817 0.000235358234624215 210.98690671031 224.728651831808 0.938851833046272 0.348224243102713 STEAP3 other 1 1 1 3.70243008615817 0.938851833046272 1.15746061703755e-08 55.2082382551713 46.2533821989758 1.19360435130285 0.233157848682473 -611.824207266223 110.939784055327 -5.5149215628642 5.42143762508038e-08 EPB41L5 other 8.91591913304028e-05 0.000724032994829485 1 1.19360435130285 -5.5149215628642 0.0503998496161745 263.74874874585 134.067305663011 1.9672861138032 0.0496626479400983 627.945112761273 324.770875687789 1.9335019232603 0.0536976861414802 TFCP2L1 other 1 1 1 1.9672861138032 1.9335019232603 9.07150670764994e-23 397.579610113857 39.941773363739 9.95397992205319 1.5106974515379e-21 -95.6306059151914 115.043761119641 -0.831254167844348 0.406196781724735 SF3B6 other 1.13330333298671e-18 1 2.10636545667929e-17 9.95397992205319 -0.831254167844348 2.80580995194772e-07 69.5422406472502 13.8516583939956 5.02049925497695 7.00701619584652e-07 -40.7979997073517 39.8967483210548 -1.02258959499768 0.306958968508736 TP53I3 other 0.00196210289939704 1 0.00680801693588448 5.02049925497695 -1.02258959499768 7.42571223429957e-07 -1.96365432775075 4.64443792766551 -0.422796979598727 0.672611390218615 -70.9330140345381 13.4080001192543 -5.29035004502099 1.77596773666659e-07 DNAJC27 other 0.00502052404160994 0.00232367618665457 1 -0.422796979598727 -5.29035004502099 6.37996009422683e-05 25.7768918662533 6.06906969398253 4.24725586720664 2.548417847114e-05 41.0470575589 17.8569860109859 2.29865541327339 0.0219055549377906 POMC other 0.355874174055973 1 0.222171067911398 4.24725586720664 2.29865541327339 1.32307451682306e-11 -37.4007458206398 33.5354117515237 -1.11526126763422 0.265239185264609 -579.769244119331 81.2206206495987 -7.13820258306774 3.0970398521318e-12 STAM2 other 1.19156090985085e-07 4.52725285584627e-08 1 -1.11526126763422 -7.13820258306774 0.0720810760842152 4.45472044137374 1.94988631754633 2.28460521071783 0.0227194815304621 1.73934363915885 5.86018184878913 0.29680711009305 0.766726857512451 OTOF other 1 1 1 2.28460521071783 0.29680711009305 4.44076827419895e-05 98.7903637867354 104.162785473879 0.948422830066393 0.343336915170251 -1002.39647980845 256.364807219366 -3.91003933293669 0.000103987912244624 GPD2 other 0.253257014677566 1 1 0.948422830066393 -3.91003933293669 3.84844567556424e-21 118.83414238484 11.7715526713963 10.0950270284731 4.46743685567351e-22 112.689898369972 35.2348025767687 3.19825542159476 0.00146321277821981 CENPA essential 4.6639313142163e-17 1 6.25396485425734e-18 10.0950270284731 3.19825542159476 0.48068349672161 -18.7688438614402 17.1722963855788 -1.0929722758106 0.274891518875394 -35.5390381792986 42.6303317141664 -0.833656149278536 0.404842010892709 CYTIP other 1 1 1 -1.0929722758106 -0.833656149278536 8.45181361025433e-12 40.7657355307682 29.3580957433891 1.38856879162361 0.165534280699905 -466.510433986513 72.8816537948865 -6.40093095718479 3.34681393131249e-10 ACVR1 other 7.68861484124837e-08 4.7370804383797e-06 1 1.38856879162361 -6.40093095718479 0.00047154057103262 68.2029517702616 44.8589291109204 1.52038742613805 0.128993555683478 -331.295448465003 111.389568836753 -2.97420532213868 0.00306756449368924 TANC1 other 1 1 1 1.52038742613805 -2.97420532213868 7.19129997889459e-11 105.173899293142 22.3624362403716 4.70315032595906 3.2574706859804e-06 -266.134868285735 68.2009531538246 -3.90221625914052 0.000107358377841118 MPV17 other 6.24995881165728e-07 1 0.0303367358342784 4.70315032595906 -3.90221625914052 9.13514389963083e-26 356.383513960237 34.349543836726 10.3752036898725 4.07457371699203e-23 -208.060170028497 104.536675466869 -1.99030789050143 0.0470616674401308 GTF3C2 essential 1.19286709041379e-21 1 5.75940994896823e-19 10.3752036898725 -1.99030789050143 2.9707593415717e-15 119.389695279614 18.9707445950011 6.29335842258264 6.44764515481958e-10 -229.332542532077 57.7293368405667 -3.97254766957455 8.07907802545953e-05 EIF2B4 essential 3.09196632270783e-11 0.916813774329147 7.22845498306823e-06 6.29335842258264 -3.97254766957455 1.6718989569658e-22 523.225798449798 54.2784290555833 9.63966362980022 2.17362359905148e-20 -311.11116495433 165.99322888355 -1.87424009429074 0.0614400353481024 NRBP1 essential 2.07900635298697e-18 1 3.00068737849057e-16 9.63966362980022 -1.87424009429074 0.0259889661137463 24.8154986696296 9.15997476466948 2.70912303878219 0.00696072197230621 20.0729153015289 28.0764353950997 0.714938168576496 0.474956790352989 FNDC4 other 1 1 1 2.70912303878219 0.714938168576496 0.729005180262907 -18.8222791414052 28.326628840317 -0.664472968086326 0.506670757473827 -46.2269272671756 76.8163175630977 -0.601785255186235 0.547569190491157 ITGA4 other 1 1 1 -0.664472968086326 -0.601785255186235 8.82742411030247e-13 326.783229372481 45.6589091271614 7.15705293051089 2.67626139590644e-12 -36.1752248780231 112.610294534953 -0.321242609544857 0.748149699314623 PSMD14 essential 8.35515692040129e-09 1 3.22328922522971e-08 7.15705293051089 -0.321242609544857 2.55458490283045e-14 288.09239339884 48.725408558375 5.91257009274112 5.99487890722662e-09 -600.069882117563 148.252484448474 -4.04762108608116 5.93491142537167e-05 SNX17 other 2.56965695375715e-10 0.680674991375877 6.47327024402331e-05 5.91257009274112 -4.04762108608116 0.00867571421838179 25.3575026518617 9.54470570424777 2.65670869669419 0.00812333260100788 -39.5593757801992 34.0046429582631 -1.16335218778077 0.245198540782579 ASB3 other 1 1 1 2.65670869669419 -1.16335218778077 3.57767879294122e-23 762.2339054158 72.409216029114 10.5267526320037 1.106564036536e-23 165.624510988035 221.803426203993 0.746717549961151 0.455561477782719 PPM1G other 4.49535340333064e-19 1 1.57154224468843e-19 10.5267526320037 0.746717549961151 0.00286045355282177 -13.4533081914779 5.20984935724053 -2.58228353047883 0.0100760734832486 -40.3374030101787 14.1557093288586 -2.84955010540833 0.00454461746632566 PDE1A other 1 1 1 -2.58228353047883 -2.84955010540833 1.54576351582702e-11 -30.433878040662 164.061734757257 -0.185502598065852 0.852906899250632 -1886.9857746594 293.053605448885 -6.43904643919671 2.72962303120154e-10 REEP6 other 1.38701360275158e-07 3.87087842054691e-06 1 -0.185502598065852 -6.43904643919671 1.78155502845701e-12 -4.79389705936941 12.4447630815729 -0.38521400752641 0.700240103077563 -151.916985181968 22.3085365935913 -6.80981401646985 2.76840226275787e-11 PCSK4 other 1.66753550663576e-08 3.9936971042545e-07 1 -0.38521400752641 -6.80981401646985 0.00112559354965698 4.25852096312515 4.98431663017637 0.854384117040826 0.393296508332418 -24.7779067203265 8.99427995441197 -2.75485162191023 0.00608341513608264 APC2 other 1 1 1 0.854384117040826 -2.75485162191023 0.0103629824227534 273.49177094376 90.1061280428163 3.035218324039 0.00251881357461084 191.351300357772 219.657472338828 0.871134946243063 0.384065450094605 IFIH1 other 1 1 1 3.035218324039 0.871134946243063 1.16753205063631e-10 491.953931947219 261.249275068483 1.88308247675811 0.0602386408460591 -2298.12388814279 467.82532362674 -4.91235461630626 1.20214054185691e-06 RPS15 essential 1.00314353790672e-06 0.0152072592885455 1 1.88308247675811 -4.91235461630626 5.10090159408506e-07 69.0593366212468 16.2292809739841 4.25523082211407 2.45991578730931e-05 -77.0021528260115 39.5631564029479 -1.94630964328908 0.0521329722918425 GCA other 0.00348901669035418 1 0.214775247389976 4.25523082211407 -1.94630964328908 0.00173430064772638 27.2760770218622 15.6897898999106 1.73846031054995 0.0826997089542763 -152.781056003524 53.6814439369745 -2.84606830216599 0.00459448155579138 INO80B other 1 1 1 1.73846031054995 -2.84606830216599 8.51874788575302e-10 262.416722115555 40.2589719897519 6.51821716119215 1.63458645597012e-10 0.726293697901978 137.743064860314 0.00527281499535759 0.995794869123407 MOGS other 6.99729951335753e-06 1 1.87013036427541e-06 6.51821716119215 0.00527281499535759 0.000966186390534164 13.3892344845065 13.6470081840347 0.981111339859106 0.326978004882489 -160.332360410335 46.6829897196169 -3.43449212171947 0.000639367420135394 TTC31 other 1 1 1 0.981111339859106 -3.43449212171947 7.56860981276588e-09 162.509067953112 55.783183054687 2.91322687329973 0.00372865814536483 -340.458136220615 99.8922797341646 -3.40825274111923 0.000703720585342191 NDUFS7 other 5.90200193199483e-05 1 1 2.91322687329973 -3.40825274111923 3.15585542158389e-08 36.6204596093295 8.02928693713558 4.56086074592244 6.30939142196568e-06 -86.2617208349298 27.4716053764481 -3.14003203136005 0.0017817166297127 PCGF1 other 0.000236878507944087 1 0.0576930751624542 4.56086074592244 -3.14003203136005 0.330891931587782 86.6098417006543 101.102159464066 0.856656694177118 0.39201323195741 350.38363410577 247.673569939826 1.41469933263731 0.157730896265118 GRB14 other 1 1 1 0.856656694177118 1.41469933263731 0.00337551730340059 88.3010580771097 26.0647924328418 3.38775220653013 0.000755389089541996 46.7186337938188 80.7679614199589 0.578430270771623 0.563211730764291 CLIP4 other 1 1 1 3.38775220653013 0.578430270771623 0.00130562999064307 1414.65444286476 410.127190731298 3.44930664153793 0.000605765045268159 -1015.64383294829 1444.47601353158 -0.703122671082057 0.482281207640337 SPTBN1 other 1 1 1 3.44930664153793 -0.703122671082057 2.12441048251491e-10 429.114265395464 71.6127141421598 5.99215195982686 3.79047087518333e-09 -569.750876463724 244.964534609058 -2.32585046391715 0.0203965933549317 AUP1 other 1.80723599747543e-06 1 4.12213707676188e-05 5.99215195982686 -2.32585046391715 1.30428756684256e-06 886.660689866455 221.658545692334 4.00011958527038 7.20874750639297e-05 -2143.87562795311 771.590209561281 -2.77851585127304 0.00564980451295883 RTN4 other 0.00862134081682929 1 0.603444253760155 4.00011958527038 -2.77851585127304 8.24336841294923e-09 101.988824846436 19.5285466598193 5.22255069069129 2.52481771931277e-07 -170.621161456251 66.9527223589089 -2.54838273105034 0.0110985901511553 HTRA2 other 6.40921894106803e-05 1 0.0025210304927338 5.22255069069129 -2.54838273105034 7.94405520779828e-06 63.8362652100951 14.045797138525 4.54486595388768 6.78622572232351e-06 -54.7820138873359 48.2842359597163 -1.13457348549619 0.257056516700584 LOXL3 other 0.048712946534219 1 0.061924309716202 4.54486595388768 -1.13457348549619 0.68885359586722 -23.2163084300578 27.4667514698017 -0.845251337988875 0.398343494505729 4.75563074785322 94.4393405934017 0.0503564586322989 0.959856885054626 DOK1 other 1 1 1 -0.845251337988875 0.0503564586322989 0.0214998958296883 205.230808416179 74.0870820962285 2.77012945589642 0.00579630695605132 104.422925584728 183.431092349302 0.569276038469412 0.569405535330105 GALNT3 other 1 1 1 2.77012945589642 0.569276038469412 0.000109726553258276 118.59195071357 31.3975521077408 3.77710817412203 0.000176085788666748 -158.398165492154 107.091861172954 -1.47908686764104 0.139693784723698 POLE4 other 0.592852567254463 1 1 3.77710817412203 -1.47908686764104 0.726803665117695 -6.48231355572899 8.14283841115485 -0.796075425842774 0.426334804488425 -1.4083212042212 27.7684058847654 -0.0507166745568874 0.959569871329253 TACR1 other 1 1 1 -0.796075425842774 -0.0507166745568874 3.95212339690321e-11 297.115355901785 42.483039205831 6.99374059521157 7.89914370730912e-12 311.393280803626 149.07126314043 2.08888872505417 0.0371827811815427 CCDC88A other 3.48103028799234e-07 1 9.39761126858566e-08 6.99374059521157 2.08888872505417 0.605403409625431 7.24155003104126 7.28893582379644 0.99349894224607 0.320909374644014 2.55602932678839 16.9281270235009 0.150993037991736 0.880037283534002 ACADL other 1 1 1 0.99349894224607 0.150993037991736 0.0106135031038813 23.1417159680616 9.15785475728278 2.52698001676191 0.0117871052278962 63.2778940307267 31.5008474402759 2.00876799110559 0.0450553670349082 EVA1A other 1 1 1 2.52698001676191 2.00876799110559 1.34734296552408e-17 214.217529785727 25.2163703443401 8.49517701637853 1.90638391407286e-16 -184.780426545973 86.7206454929492 -2.13075474122245 0.0335580164677072 MRPL19 essential 1.50444315530419e-13 1 2.50060378008937e-12 8.49517701637853 -2.13075474122245 3.59530253927061e-09 157.946598094146 62.7696631651699 2.51628876322835 0.0121475055020398 -710.998908351184 145.300310747591 -4.89330617872041 1.30958325503577e-06 LANCL1 other 2.85862504897406e-05 0.0165413460943568 1 2.51628876322835 -4.89330617872041 1.44404022756533e-13 239.225935885421 33.950632526663 7.04628803889135 5.65047908617453e-12 -149.475555554875 88.4317008038521 -1.69029379957786 0.0915510167829362 WDR75 essential 1.41183813049062e-09 1 6.74667202889239e-08 7.04628803889135 -1.69029379957786 0.136082685755593 393.312783457436 265.825669417457 1.47958917706992 0.139561757555419 1444.47652728892 938.744532363805 1.5387322934938 0.124451094692166 EFEMP1 other 1 1 1 1.47958917706992 1.5387322934938 8.49500172572076e-05 147.445297484529 33.9889423387014 4.33803723620551 1.71386908154609e-05 12.5219542008488 120.72680070512 0.103721411713992 0.917428660308855 FANCL other 0.465950844655784 1 0.151415567297819 4.33803723620551 0.103721411713992 0.0436428416328244 15953.0973826686 8497.13566286479 1.87746765682332 0.0609888556803127 -20504.1829071652 19401.8527639789 -1.05681571531318 0.291064776371179 FN1 other 1 1 1 1.87746765682332 -1.05681571531318 8.11170808585779e-08 3090.91168156941 538.601666423542 5.73877110721526 1.5939592676971e-08 816.37262194344 1369.51802373678 0.596102137974015 0.55135770393505 STAT1 other 0.00059037011448873 1 0.000169246595044078 5.73877110721526 0.596102137974015 0.000681900217273163 342.819099890336 94.4906121442648 3.62807576446783 0.000312804675307552 522.921175950704 240.938403921379 2.17035212087376 0.0304177235432207 GLS other 1 1 1 3.62807576446783 2.17035212087376 1.45533312609249e-07 51.7991663166548 10.9762378712988 4.71920952552438 3.01868597521909e-06 -93.9565179979768 40.2860197590596 -2.33223630827535 0.0200542187748804 PAPOLG other 0.00104143638503179 1 0.0282005643804968 4.71920952552438 -2.33223630827535 0.00184196995378282 -5.65435991231055 2.82154380492541 -2.00399508327322 0.0455658737858433 -32.5709446371347 10.1504834937064 -3.20880721172834 0.00141138631260778 DNAH6 other 1 1 1 -2.00399508327322 -3.20880721172834 1.23409452160191e-07 43.8283943332515 13.0584918129158 3.35631365100692 0.000844952333537917 -104.244720747518 29.9237904365884 -3.48367366655715 0.000534337892208441 PECR other 0.000887190551579615 1 1 3.35631365100692 -3.48367366655715 2.0560337831775e-09 42.5635326525557 12.3311732882294 3.451701768978 0.00060028432063533 -200.625745187244 42.4836793848592 -4.72241924645409 2.96810803415825e-06 UNC50 essential 1.65798564275434e-05 0.0368787423244163 1 3.451701768978 -4.72241924645409 0.00485317265587548 296.504352550589 430.117371318505 0.689356841463224 0.490892662567773 -2849.41690630899 988.503776828106 -2.88255540656825 0.00410055674546487 IGFBP2 other 1 1 1 0.689356841463224 -2.88255540656825 0.515743428794683 15.2842611801139 23.6901745551233 0.645173008098775 0.519087575252388 -74.6734710837827 86.7877037496329 -0.860415333711357 0.389939870965037 ELMOD3 other 1 1 1 0.645173008098775 -0.860415333711357 0.673481776913818 722.369430639417 5698.847937596 0.126757098724087 0.899179574904982 -10410.2098144777 12810.3992374067 -0.812637422265471 0.416782103917975 IGFBP5 other 1 1 1 0.126757098724087 -0.812637422265471 2.54689387640927e-07 354.622806027048 84.3630100799209 4.20353429413077 3.0735299392155e-05 -893.955170554601 307.381914680974 -2.90828811930078 0.00378310825917643 USP34 other 0.00178741012246403 1 0.26656725162816 4.20353429413077 -2.90828811930078 7.9752555975561e-06 20.5864415132132 450.855741319931 0.0456608170341673 0.96359728956457 -4154.76660261223 897.032920589917 -4.63167683955225 4.53916362619536e-06 EFHD1 other 0.0488962920686164 0.0558861825657172 1 0.0456608170341673 -4.63167683955225 2.82599480126197e-30 1287.08674042409 104.167115285505 12.3559794940697 4.56046480261128e-31 235.310213086665 376.609080665134 0.624812903265851 0.532357285819587 CCT4 essential 3.87500407149042e-26 1 6.73124604865425e-27 12.3559794940697 0.624812903265851 3.41642222291875e-06 170.73259532142 38.7003972195485 4.41164968806003 1.23799581055988e-05 -268.679525922026 141.149840426599 -1.90350570082115 0.0575040171573878 GGCX other 0.0217045303822028 1 0.11071396533837 4.41164968806003 -1.90350570082115 2.06702527910187e-10 229.671831708881 34.5176165096859 6.65375697781547 7.01402552249731e-11 -46.4814197631716 124.560755824893 -0.373162634212939 0.709173571563309 EHBP1 other 1.75986532262733e-06 1 8.11312332187264e-07 6.65375697781547 -0.373162634212939 2.89099601189229e-09 77.2061497471568 12.4405222090634 6.20602161627181 1.07799767430922e-09 110.427050949169 43.8285506130061 2.5195232195609 0.0120367178014123 OTX1 other 2.30891927096779e-05 1 1.19851781429699e-05 6.20602161627181 2.5195232195609 4.88777582225909e-16 132.101064288838 16.3026970507754 8.10301902055861 3.57722010149639e-15 -86.7912373994561 52.4924507940442 -1.65340417691649 0.0988276750436163 TXNDC9 other 5.21525680235045e-12 1 4.58778478016912e-11 8.10301902055861 -1.65340417691649 3.28437462260796e-15 91.7039120387021 18.3269988257992 5.00376045801941 7.63121159630083e-07 -259.612958154185 47.0309263492972 -5.52004772829792 5.28224499299475e-08 COQ10B other 3.41476429512549e-11 0.000705496641264379 0.0073969334002944 5.00376045801941 -5.52004772829792 0.123702064919109 17.1298678652469 8.67926161445803 1.97365497506283 0.0489284518916048 -8.91396095505915 31.655395807737 -0.281593729208101 0.778362526844987 GNLY other 1 1 1 1.97365497506283 -0.281593729208101 8.24213816293432e-08 657.01108703451 177.271235238227 3.70624758242126 0.000232134473109765 -1610.24525906611 455.06747667883 -3.5384758120224 0.000437256226735726 SF3B1 essential 0.000599450708590213 1 1 3.70624758242126 -3.5384758120224 0.0788900875260821 39.5043882471623 19.7237662619541 2.00288259972761 0.0456883151651094 -55.8017990686245 72.1945775049191 -0.772936153893585 0.439897728865873 ST3GAL5 other 1 1 1 2.00288259972761 -0.772936153893585 0.00309585341375005 -9.75095341029258 19.768203526409 -0.493264519320938 0.62202548896981 -211.362474054253 61.9551540152407 -3.41153980510256 0.000694165260958477 CHST10 other 1 1 1 -0.493264519320938 -3.41153980510256 9.38804520534599e-29 128.453282364003 11.1226988610056 11.5487512490642 9.5771584317888e-28 -39.0766464878789 35.3522219988974 -1.10535192071089 0.26949574146108 PDCL3 other 1.2698269944751e-24 1 1.393093465488e-23 11.5487512490642 -1.10535192071089 8.12810618843921e-15 180.886604407557 25.0720264818492 7.21467826059092 1.85177606041971e-12 -156.525392703587 64.3400832893357 -2.43278194092004 0.0153087921011028 MOB4 other 8.33618570686326e-11 1 2.23935278986555e-08 7.21467826059092 -2.43278194092004 7.11536933155001e-12 416.266657027366 56.7645345666561 7.33321712588979 8.3274186182135e-13 277.938146524199 145.669712200689 1.90800230415286 0.0569239461501914 HSPE1 essential 6.5020244951704e-08 1 1.01353012002276e-08 7.33321712588979 1.90800230415286 0.000138889237796375 181.986933080361 50.0083436658045 3.63913138768488 0.000299737890806654 -276.411602764452 179.056974127037 -1.54370754957773 0.123242834867708 KDM3A other 0.740937643975819 1 1 3.63913138768488 -1.54370754957773 0.0306442634131235 0.207594151976966 25.4129354021359 0.008168837983176 0.993485277499198 -147.595297393858 57.9053638307785 -2.5489054489872 0.0110796220353812 PLCD4 other 1 1 1 0.008168837983176 -2.5489054489872 7.15572274030088e-06 251.387031909969 60.3732470982059 4.1638812552363 3.63953735253721e-05 -405.866426630661 216.168946043712 -1.87754270009065 0.060980533907264 CHMP3 essential 0.0440434734665519 1 0.313182189185827 4.1638812552363 -1.87754270009065 4.44700571035987e-10 41.3521667103232 17.9671679792967 2.30154060773366 0.0217380972413752 -222.552119877357 40.9395995537944 -5.43610886044268 8.23394383133994e-08 ZNF142 other 3.71502857043463e-06 0.001093220722487 1 2.30154060773366 -5.43610886044268 0.896949403494903 -0.501680909905715 6.21168387134718 -0.080764076262772 0.935659172315539 10.2929374943082 23.3875894089253 0.440102539613602 0.660037005923556 IL1R2 other 1 1 1 -0.080764076262772 0.440102539613602 0.950525577496699 13.2290674496442 45.7060685529011 0.289437877036671 0.77236101490578 31.6139927435564 176.078728869814 0.179544644299032 0.857579603939692 SMYD1 other 1 1 1 0.289437877036671 0.179544644299032 0.6692238594765 1.39832979422562 83.7660391844353 0.0166932781809916 0.986687396538539 -277.034691435586 314.589449888787 -0.880622956470801 0.378908674399457 IL1R1 other 1 1 1 0.0166932781809916 -0.880622956470801 0.0710390028687226 5.06564737947064 7.49013832686504 0.676308922266706 0.499134625609574 39.3325725684894 17.067318546741 2.30455489892992 0.0215707310428812 WNT6 other 1 1 1 0.676308922266706 2.30455489892992 0.00062091243179863 6.43814258108231 2.663948437635 2.41676696520371 0.0159846511683014 35.2675143243078 10.4295951195256 3.38148450827994 0.000772372989643783 IL1RL2 other 1 1 1 2.41676696520371 3.38148450827994 0.614725195437212 -11.0189639079204 12.5969441288994 -0.874733093611263 0.38210235073529 -29.1742364234108 48.8886805202345 -0.596748288416906 0.550921893957769 IL1RL1 other 1 1 1 -0.874733093611263 -0.596748288416906 0.523788627153333 -2.2403770290407 2.45793250606 -0.911488425136603 0.362438856589245 4.95411654498849 9.53922441819753 0.519341649572449 0.603732198410954 IL18R1 other 1 1 1 -0.911488425136603 0.519341649572449 0.325816545063898 1.16788378360934 0.807030973282252 1.44713625904526 0.14843054554426 1.73318148406594 2.62484162255962 0.660299451658277 0.509339125163238 IL18RAP other 1 1 1 1.44713625904526 0.660299451658277 0.00354925285006531 62.7587838368814 19.3558204250527 3.24237270540345 0.00125760923368197 -18.9402794846684 62.1555835285529 -0.304723701547546 0.760692498604585 SLC9A2 other 1 1 1 3.24237270540345 -0.304723701547546 0.0598436092067138 -80.640142273308 138.532762990722 -0.58210159483146 0.560738523208539 -1038.92922262701 437.032942000409 -2.37723320780253 0.0177865592313733 FHL2 other 1 1 1 -0.58210159483146 -2.37723320780253 7.18779488695305e-15 -644.505326408104 574.597588897948 -1.12166381979471 0.262497551278659 -9080.42197287761 1118.3301247462 -8.11962565609898 3.11578597578842e-15 MLPH other 7.38617802583295e-11 4.68863473636642e-11 1 -1.12166381979471 -8.11962565609898 2.44697488577004e-15 175.618211017951 44.6864968891504 3.93000622656974 9.59397935529728e-05 -617.662373369051 100.169651969821 -6.16616271717847 1.36827457390948e-09 CNPPD1 other 2.55366299078962e-11 1.91120592483677e-05 0.794381490618615 3.93000622656974 -6.16616271717847 2.63316796471572e-10 136.332119399934 20.2727676419916 6.72488935933664 4.43401911268712e-11 26.9386802936982 63.8744562150119 0.421744182103378 0.673377443013432 UXS1 essential 2.22555356377773e-06 1 5.15632082614385e-07 6.72488935933664 0.421744182103378 0.000133015473548541 143.674173465771 34.9361693121875 4.11247644760098 4.52320836532666e-05 2.76561166084083 78.3157539747189 0.0353136057623042 0.971842699776113 ABCB6 other 0.712297860852439 1 0.385739209395057 4.11247644760098 0.0353136057623042 5.71168026682337e-19 23.5445823716659 19.9687540349054 1.17907117942912 0.238889071005259 -395.541286722927 44.9466747243291 -8.80023470365485 1.84447695488839e-17 STK16 other 6.59641954015431e-15 2.81338069929125e-13 1 1.17907117942912 -8.80023470365485 1.00760102725141e-12 2496.59785290639 494.043261374042 5.0533992629771 5.93324750040828e-07 -3378.58591310267 955.816886173413 -3.53476273748285 0.000442840146071733 HDLBP other 9.52082210649857e-09 1 0.00578728961189824 5.0533992629771 -3.53476273748285 1.07625493092231e-20 194.901770746426 35.209120943847 5.53554776494599 4.8242502488812e-08 -397.778441063605 68.4129830297074 -5.81437065667601 1.03642536857065e-08 PPP1R7 essential 1.29182879358605e-16 0.00014162752661518 0.000501398594412722 5.53554776494599 -5.81437065667601 3.74399525977758e-06 51.775418422284 18.4528182263181 2.80582715264815 0.00519779640076608 -105.033120628689 35.8546963492989 -2.92941040709002 0.00353797804605044 PASK other 0.0236920020038725 1 1 2.80582715264815 -2.92941040709002 9.44976961859928e-10 216.042830683243 49.864715541248 4.33257922637767 1.7549155240466e-05 -296.449101752354 96.4723959719672 -3.07289042389386 0.00222594756233469 STK25 other 7.74503117940397e-06 1 0.154888844152353 4.33257922637767 -3.07289042389386 1.19177330980883e-05 -9.39985059823818 2.62062430262707 -3.58687454314424 0.000364715921685304 -31.8917224985489 8.14099933230851 -3.9174210925166 0.00010085348450105 TPO other 0.0719592724462574 1 1 -3.58687454314424 -3.9174210925166 0.0958726891724854 -3.02178739669139 3.4933366769548 -0.865014648208925 0.387414856213754 -17.8809667215572 8.28046414140568 -2.1594159960364 0.0312574897474498 PROC other 1 1 1 -0.865014648208925 -2.1594159960364 6.19041248887085e-05 235.303993512205 58.63018050469 4.0133595272384 6.83022532212379e-05 -178.347690394574 180.448780926914 -0.988356305198922 0.323420004261506 ID2 other 0.34561072925366 1 0.573055904526186 4.0133595272384 -0.988356305198922 1.73299987033161e-23 64.4980204786742 7.37067721343008 8.75062339742033 2.70124867133939e-17 -90.2455471933983 22.2426799360348 -4.05731447167901 5.69528686843682e-05 TAF1B essential 2.18808563628069e-19 0.654046743971285 3.59455160695132e-13 8.75062339742033 -4.05731447167901 1.40506676520935e-06 232.124582958565 46.115206768026 5.03358001030387 6.55788124982175e-07 -20.7001807279485 135.1323133793 -0.153184536032072 0.878309659901715 HPCAL1 other 0.0092607950494948 1 0.00638081845607657 5.03358001030387 -0.153184536032072 1.54203103627084e-08 449.468261279484 73.8597703945979 6.08542727493177 2.19361930637682e-09 429.48763565431 217.35312577637 1.9759901502231 0.0486607129377523 ODC1 other 0.000117872852412543 1 2.40705846488728e-05 6.08542727493177 1.9759901502231 2.42534693644015e-05 243.603205487818 85.4072714079288 2.85225369540612 0.00450579565373704 -783.188515917373 267.082832377873 -2.93238059872492 0.00350510128205534 BIRC6 other 0.141979809659206 1 1 2.85225369540612 -2.93238059872492 2.72740929440651e-33 267.795293615105 20.851080284184 12.8432335382754 3.66159303834245e-33 41.4680320292602 61.3601619849187 0.67581360100471 0.499446182983807 NOL10 essential 3.84346517767766e-29 1 5.44222573288838e-29 12.8432335382754 0.67581360100471 7.92928384394895e-06 110.387070735916 92.9245318896573 1.18792173058235 0.235390363667783 -1047.35025025851 246.733042946864 -4.24487226254517 2.57784001438657e-05 PLEKHB2 other 0.0486302978149389 0.30294775849071 1 1.18792173058235 -4.24487226254517 3.21581969796412e-12 349.021055327633 62.8065072500812 5.5570842992098 4.31075244441124e-08 -500.769955888446 157.128287998225 -3.18701337784641 0.00152050332132413 GORASP2 other 2.98106486001274e-08 1 0.000448878652036542 5.5570842992098 -3.18701337784641 1.5663701908004e-10 271.823455792579 41.8808813721285 6.49039482663505 1.93225709654916e-10 -111.61861325388 132.658258711909 -0.841399656061217 0.40049446279321 STRN other 1.33971642419158e-06 1 2.20528502429155e-06 6.49039482663505 -0.841399656061217 9.09095642462638e-14 260.488722441269 34.7910282045443 7.48723840266511 2.8682202634548e-13 -131.294884524105 110.635433873824 -1.18673448394338 0.235852268017643 CEBPZ essential 8.95277388697206e-10 1 3.53536829673438e-09 7.48723840266511 -1.18673448394338 1.02954969267339e-12 357.607051101278 47.3984560429336 7.54469830783848 1.92690140560551e-13 387.296304281246 150.727041420822 2.5695210403549 0.0104501550108724 PRKD3 other 9.72409684730014e-09 1 2.38473317957738e-09 7.54469830783848 2.5695210403549 1.51135863596619e-06 25.4526068131937 15.0062188686836 1.69613725055754 0.0904351782874152 -158.945236286008 37.1939860424572 -4.27341226897732 2.27495166581654e-05 DCAF17 other 0.00992358080375401 0.268489795599668 1 1.69613725055754 -4.27341226897732 0.0620728793067545 97.275564827793 41.3952392405958 2.34992155166471 0.01913508262722 94.4911686029253 131.636818169572 0.717817172405393 0.473179294944299 QPCT other 1 1 1 2.34992155166471 0.717817172405393 1.79218974261617e-16 182.313901021503 50.3790336631057 3.61884474086325 0.000323578959973858 -733.320013072827 114.781621404978 -6.38882779400275 3.59774059175848e-10 RAB3GAP1 other 1.93753633074234e-12 5.08864429298319e-06 1 3.61884474086325 -6.38882779400275 2.08059510934659e-06 -2.42790464997209 28.2272730368148 -0.086012724176563 0.931488066434066 -345.2681136377 69.415788155447 -4.97391332450941 8.82149495165901e-07 SLC25A12 other 0.0135093040449874 0.0112350559704329 1 -0.086012724176563 -4.97391332450941 0.0242480679130156 -1.45018732577793 2.38783102542881 -0.607324098872327 0.543890193735129 -20.776861304679 7.59364004138387 -2.73608719816177 0.00642132290078261 RMDN2 other 1 1 1 -0.607324098872327 -2.73608719816177 0.0102121243702607 -32.9969001072951 14.9809651427103 -2.20258840421582 0.028043975837193 -97.6568629112409 36.840806455311 -2.65077972790041 0.00826541501569483 DLX2 other 1 1 1 -2.20258840421582 -2.65077972790041 0.0207844981509171 12.9203921692503 4.75427397930901 2.71763727237447 0.0067853480176345 16.5993773928602 10.9229132111428 1.51968408720181 0.129173501065942 LCT other 1 1 1 2.71763727237447 1.51968408720181 2.25092634248459e-19 422.895664864282 52.1395470754486 8.11084270165083 3.37766875315588e-15 -264.336264177734 119.732314011658 -2.2077270147138 0.02768137396096 DARS essential 2.63200817226723e-15 1 4.33321124342368e-11 8.11084270165083 -2.2077270147138 3.4450039993616e-08 247.65959327538 43.6129706368468 5.67857657157942 2.21880646938214e-08 -90.5106829828966 136.978048688329 -0.660767793450165 0.509042505243091 SRSF7 essential 0.00025789299939221 1 0.00023410627058451 5.67857657157942 -0.660767793450165 2.36824991514916e-05 1941.79096618262 463.897454403902 4.18581940415643 3.31516707333917e-05 -1323.11169392388 1339.47715459341 -0.98778220247101 0.323700077063344 SDC1 other 0.138684715031135 1 0.286430435136504 4.18581940415643 -0.98778220247101 0.0144908089958545 -19.3387625451971 32.962016298478 -0.58669840977204 0.557652369452956 -245.123982022776 83.9422004054502 -2.92015197169958 0.00364528825511679 PLCL1 other 1 1 1 -0.58669840977204 -2.92015197169958 0.0908632756602424 -245.566329064227 147.691316883243 -1.66269984076558 0.0969496042335356 -866.082283197276 512.1357325473 -1.6911186393683 0.0913879640600734 SLC1A4 other 1 1 1 -1.66269984076558 -1.6911186393683 6.4469742684995e-10 286.729455845625 44.9314747588396 6.3814833006169 3.77721717796287e-10 -78.2506419922137 142.255731001946 -0.550070225227996 0.582498651357108 SOS1 other 5.33229241747594e-06 1 4.27505440201837e-06 6.3814833006169 -0.550070225227996 0.463640528596066 105.293246231815 102.116463522074 1.03110940782878 0.302958044430131 -73.6975110659894 238.7102325598 -0.308732098644021 0.757646184427796 KYNU other 1 1 1 1.03110940782878 -0.308732098644021 0.357983063657059 18.4825603585505 57.6038543668296 0.320856313552403 0.748442956891894 -174.39567635414 140.477936977271 -1.24144531238636 0.214978278067399 WIPF1 other 1 1 1 0.320856313552403 -1.24144531238636 4.71547622304042e-15 78.4601847481627 13.9893857088827 5.60855111017088 3.26383964567992e-08 -162.85456139168 34.685826091024 -4.69513284660743 3.38410401859866e-06 ORC2 other 4.87533086700149e-11 0.0419290487904374 0.000341789287695601 5.60855111017088 -4.69513284660743 5.68542774896379e-15 307.957570305494 39.7774356850083 7.74201667357757 4.81556656226238e-14 -219.018010226956 127.339172588715 -1.71995785565804 0.0860098893916453 COX7A2L other 5.86281309473146e-11 1 6.04305447898306e-10 7.74201667357757 -1.71995785565804 1.30136964081589e-21 151.331121289201 15.5432300448726 9.7361437006539 9.19183859502486e-21 -72.5818031010046 50.6964265209903 -1.4316946594047 0.152803390805715 PNO1 essential 1.59027370107702e-17 1 1.27306964541094e-16 9.7361437006539 -1.4316946594047 5.92688162326909e-19 68.1351345751524 18.1282898110865 3.75849764567885 0.000190038490823466 -298.469530720257 42.3725089197849 -7.04394283768487 5.8663108555931e-12 ORC4 essential 6.84258483406416e-15 8.54486839225691e-08 1 3.75849764567885 -7.04394283768487 0.0546246201407595 38.3935697429325 30.9920652505019 1.23881933754998 0.215943735059746 228.875632544188 101.102855251952 2.26378999854971 0.0239778925892499 PLEK other 1 1 1 1.23881933754998 2.26378999854971 0.0484236086844712 -1.20247957012553 74.4377035278042 -0.016154173397845 0.987117451320312 -410.998404798688 175.838283260621 -2.33736588629861 0.0197900971265065 RND3 other 1 1 1 -0.016154173397845 -2.33736588629861 2.09296165958292e-09 118.679134670441 31.0423967722681 3.82313052503934 0.000147033347081296 -292.3073987317 75.3595935814828 -3.87883459609746 0.000117832294298078 ATF2 other 1.68713639378979e-05 1 1 3.82313052503934 -3.87883459609746 3.03159767908959e-10 119.763630591862 23.5414619021742 5.08734891187029 5.01550613429551e-07 -266.694553791155 76.1341101643286 -3.50295752082107 0.000498188556327827 THADA other 2.55351472509716e-06 1 0.00491920841651704 5.08734891187029 -3.50295752082107 0.00939242249255839 65.0273028508692 28.4290922894176 2.28735065435329 0.0225569930605297 -160.727417737117 96.3862348459479 -1.66753497523795 0.0959814764122106 AAK1 other 1 1 1 2.28735065435329 -1.66753497523795 0.000103542334641295 -71.5822773861954 83.1525629354604 -0.860854733266065 0.389698005451036 -889.796213867867 206.270159534657 -4.31374182225503 1.90716040530768e-05 TRAK2 other 0.56130299609046 0.226246438881649 1 -0.860854733266065 -4.31374182225503 6.94032160770929e-05 11.9549314742105 5.47872013096479 2.18206646596953 0.0295317419386579 -62.5873456763712 18.2844024026669 -3.42299104439106 0.000665990582308875 C2orf42 other 0.385187849227866 1 1 2.18206646596953 -3.42299104439106 6.15929196415423e-05 161.800696562789 49.3438533869643 3.27904461157331 0.00110817979646738 -397.287984204287 164.677671036022 -2.41251884183729 0.0161725283704568 TIA1 other 0.343934863278372 1 1 3.27904461157331 -2.41251884183729 0.0246740360134783 191.749142338639 115.069192651331 1.66638122611719 0.096213137571268 -712.933998608771 384.026081327945 -1.8564728628417 0.063926611972604 PCYOX1 other 1 1 1 1.66638122611719 -1.8564728628417 0.0386928428760114 11.5817820718378 7.39474255847548 1.56621842887057 0.117900011319461 -13.2305879722569 13.2203096690993 -1.00077746311659 0.317395442475098 KISS1R other 1 1 1 1.56621842887057 -1.00077746311659 0.124588496362569 84.2127735564383 183.780018953826 0.458225948804566 0.646973106763436 -1193.31848324996 627.6271734472 -1.90131742814088 0.0577885616191617 EPAS1 other 1 1 1 0.458225948804566 -1.90131742814088 1.46394849989851e-09 47.1752184659691 12.7703348806541 3.6941254013186 0.000243733725928945 -65.8045898358547 22.9404629740374 -2.86849441139563 0.0042899558328807 ARID3A other 1.18872618191759e-05 1 1 3.6941254013186 -2.86849441139563 2.10717678015721e-16 378.690619898127 51.7034034496717 7.32428804743475 8.72829284742304e-13 -336.287824635887 126.703585254329 -2.65413029916134 0.00818441721150816 SUMO1 other 2.27511876953574e-12 1 1.06153497610359e-08 7.32428804743475 -2.65413029916134 0.676248401831216 -3.98241533786861 19.0224340176472 -0.209353615534905 0.834250717824655 51.358348052573 63.1285824582466 0.813551422393201 0.416258565535767 CD207 other 1 1 1 -0.209353615534905 0.813551422393201 0.0087691822519426 1.73789062334609 2.16334545349535 0.803334770476972 0.42214343736658 -8.60367610548226 3.88505809633608 -2.21455532765295 0.0272176608312828 GRIN3B other 1 1 1 0.803334770476972 -2.21455532765295 2.36454042687877e-05 23.4525376940965 5.0444312881572 4.64919360665215 4.18712195659083e-06 18.4974716289635 16.8605164157703 1.09708808276252 0.273088274546024 VAX2 other 0.138491132802289 1 0.0387183167325954 4.64919360665215 1.09708808276252 0.774139832603997 -57.7821766667945 95.9025364370816 -0.602509368505633 0.547086653436227 -154.003327549964 320.484701622475 -0.480532539526262 0.631042309212874 ATP6V1B1 other 1 1 1 -0.602509368505633 -0.480532539526262 9.5578451452878e-10 220.604804489762 72.1860142352931 3.0560601915309 0.00235416700434999 -817.309601955143 174.139151972246 -4.69342817338059 3.41427478752594e-06 NFE2L2 other 7.82978674301977e-06 0.0422823789687212 1 3.0560601915309 -4.69342817338059 2.18503908336736e-25 819.98639451899 73.4418788303895 11.1651064430515 3.29614794599024e-26 718.941082066652 258.087644542554 2.78564703607155 0.00552805819832412 MSH6 ts 2.8383657692942e-21 1 4.75337495291252e-22 11.1651064430515 2.78564703607155 3.19230512892676e-16 21.3614981668637 11.8843281254664 1.79745105834709 0.0728310057709461 -227.352169380992 29.5016016983854 -7.7064347795542 6.38329296194937e-14 PLEKHA3 other 3.42757801692866e-12 9.49770159808446e-10 1 1.79745105834709 -7.7064347795542 0.0551993378266646 -42.1971461063583 55.2401918775159 -0.763884857603718 0.445265826799798 -442.892401245276 185.976503310193 -2.38144278100857 0.0175866901422249 SPR other 1 1 1 -0.763884857603718 -2.38144278100857 0.831897088132559 -4.2223027244449 31.8711695886903 -0.132480319327321 0.894653465395602 -42.9006533171776 70.7157760990964 -0.606663119373242 0.544328056223568 EPHA4 other 1 1 1 -0.132480319327321 -0.606663119373242 5.17330032535823e-07 1.4482633355461 18.8745457098907 0.0767310301294921 0.938865730107113 -238.06204997225 45.517750862426 -5.23009255645727 2.42096230733474e-07 PARD3B other 0.00353595077238235 0.0031511245392269 1 0.0767310301294921 -5.23009255645727 3.28123633748474e-13 286.890983015654 37.7312770497784 7.6035322800541 1.2758429438923e-13 22.7194119770576 83.5014982569724 0.272083884137498 0.785660944074675 FARSB essential 3.1611430875328e-09 1 1.5849796891974e-09 7.6035322800541 0.272083884137498 0.000461437441063134 104.097634748488 32.0528473062513 3.24768760022719 0.00123573503564387 -188.2701961561 110.40992280319 -1.70519271616283 0.0887336068202626 ALMS1 other 1 1 1 3.24768760022719 -1.70519271616283 0.271980460326878 -40.3944857205985 65.3443115726892 -0.618179069430757 0.536716978977146 -748.170009805002 490.047485256455 -1.52672961766851 0.127411581039408 PRRX1 other 1 1 1 -0.618179069430757 -1.52672961766851 0.000365284537611343 1713.45949723789 946.344876577969 1.81060788687718 0.0707551597429553 -5960.69512462959 2138.85007120147 -2.7868690774016 0.00550858746120752 DHCR24 other 1 1 1 1.81060788687718 -2.7868690774016 1.75600045032966e-20 75.7901188349152 35.0357948438828 2.1632196207516 0.0309590944722506 -403.909994351777 56.6358395030756 -7.13170313878445 3.17450276307922e-12 DNAJC16 other 2.09929853836911e-16 4.63890088768766e-08 1 2.1632196207516 -7.13170313878445 0.00748465264130878 26.2659042235256 8.45112242917133 3.10797819386236 0.0019842165904744 41.613672036981 53.4614397544215 0.778386669497419 0.436686500082056 MARK1 other 1 1 1 3.10797819386236 0.778386669497419 0.378612239568508 -6.45446996350579 5.28906733628485 -1.22034180189499 0.222865028620089 -29.5114985383927 38.7181894425467 -0.762212772944467 0.446263973613928 TNR other 1 1 1 -1.22034180189499 -0.762212772944467 8.35964300455761e-14 15.9487687894618 9.27763695057308 1.71905506482193 0.0861763766320557 -120.712446075446 18.9531745572865 -6.36898297488839 4.06940615346133e-10 MORN1 other 8.248459752597e-10 5.7504778354562e-06 1 1.71905506482193 -6.36898297488839 0.00103313071773349 58.2652956599483 22.2763066209968 2.61557252965039 0.00915599889426488 -74.387043802342 46.2975178703171 -1.60671775127785 0.108698686798354 GPX7 other 1 1 1 2.61557252965039 -1.60671775127785 2.13880806571383e-23 329.236947989587 30.6957643998742 10.7258103659062 1.75318624881676e-24 151.204493067841 220.86909474663 0.684588729995453 0.493894497307901 CACYBP other 2.69618144763885e-19 1 2.50284868881081e-20 10.7258103659062 0.684588729995453 0.00014401992774108 -84.2888748514794 139.325507079096 -0.60497805906874 0.54544677171111 -1211.00095905588 290.848496294163 -4.16368306690876 3.64260099706782e-05 SCP2 other 0.766041995654805 0.423743773988899 1 -0.60497805906874 -4.16368306690876 0.0284759368365625 -0.466102251810397 12.1020156139682 -0.0385144315358857 0.969291785839586 -139.660319654057 55.074951974755 -2.5358228132105 0.0114996697837954 TPSG1 other 1 1 1 -0.0385144315358857 -2.5358228132105 0.893381958956068 -0.0213639524616384 4.37538572535884 -0.00488275864178496 0.996105934343617 -14.558336390756 30.718735413008 -0.473923688427331 0.635745175875883 PAPPA2 other 1 1 1 -0.00488275864178496 -0.473923688427331 1.379500651591e-06 256.335083066249 55.7150896751218 4.60081971618381 5.24528122063843e-06 -828.54330004254 382.4834780925 -2.16621984346776 0.0307295784160031 RALGPS2 other 0.00909918629789426 1 0.0482251155425497 4.60081971618381 -2.16621984346776 0.168124119118212 10.7902400929516 7.56690798983919 1.42597744117421 0.154448428636543 -58.4667325766731 52.0770693538361 -1.12269629036578 0.262061752317459 ANGPTL1 other 1 1 1 1.42597744117421 -1.12269629036578 3.92561257358397e-21 154.414125348096 26.4635822598487 5.83496685489844 9.25470801415855e-09 -205.162233287696 45.70863445911 -4.4884787243257 8.76383131352071e-06 CEP104 other 4.75548707163962e-17 0.106217635519871 9.91641963717088e-05 5.83496685489844 -4.4884787243257 2.05694326111526e-17 402.649934333182 45.6771983597631 8.81511889503003 1.62073957339176e-17 -462.164177880074 314.039756994749 -1.47167410363205 0.141688206207125 FAM20B other 2.28464688012072e-13 1 2.1628769606913e-13 8.81511889503003 -1.47167410363205 4.21605014159027e-09 493.273410846117 222.979907424414 2.21218771029102 0.027369903037722 -2461.82416300217 500.604805946978 -4.9176998178138 1.16266797052097e-06 TMEM59 other 3.3370036870687e-05 0.014718213838825 1 2.21218771029102 -4.9176998178138 1.04763407691666e-31 287.837087746137 28.0019538454946 10.2791787078261 9.25220482026775e-23 -251.965937060255 63.0126574587643 -3.99865594027901 7.25558550069567e-05 LRRC42 other 1.45642089372954e-27 0.826411188529237 1.30372818122393e-18 10.2791787078261 -3.99865594027901 1.39634810152111e-15 92.1489444894524 14.5318980055676 6.3411499622518 4.82889551126089e-10 -53.1225522038711 25.8410447223839 -2.05574320909152 0.0402883883572971 WRAP73 other 1.46923747242052e-11 1 5.44264813074215e-06 6.3411499622518 -2.05574320909152 1.57129364688331e-35 754.13146955279 61.7222316449109 12.2181497566602 1.70507535738976e-30 -273.508305834737 140.985047676232 -1.93998094367313 0.0529003740450796 MRPL37 other 2.25072101979565e-31 1 2.5110644788279e-26 12.2181497566602 -1.93998094367313 2.73725393786767e-19 396.292683778742 68.2695049966959 5.80482726215638 1.09665467096154e-08 -431.356989099985 112.292955999762 -3.84135394121159 0.000136801005500877 ICMT other 3.19163809155371e-15 1 0.00011721045123237 5.80482726215638 -3.84135394121159 2.13759950447982e-14 40.0967189944319 187.526167091024 0.213819327811297 0.830768214237123 -2208.21064198329 312.172681010727 -7.07368317699591 4.67120208972171e-12 RPL22 other 2.1557691002679e-10 6.81201400744117e-08 1 0.213819327811297 -7.07368317699591 0.81756109027527 1.2814123883858 11.8243257361886 0.108370863335067 0.913741545140441 11.8365922132275 19.6838207886925 0.601336109503045 0.547867095294033 CHD5 other 1 1 1 0.108370863335067 0.601336109503045 5.97656070004466e-05 1036.35660076376 233.255607872736 4.44300829555702 1.07562972861045e-05 28.6939972520858 1675.50023725092 0.0171256300740163 0.986342682640094 QSOX1 other 0.334627633595501 1 0.0966668437102212 4.44300829555702 0.0171256300740163 1.10889716398541e-17 203.2163387403 32.5677485532836 6.23980311097713 8.8712715524598e-10 -283.369726771589 76.2111672541475 -3.71821790665682 0.000221631720826064 STXBP3 other 1.24107770593247e-13 1 9.8959034167689e-06 6.23980311097713 -3.71821790665682 2.65560212958523e-16 100.354149342785 24.9930352302967 4.0152845950113 6.77308369155779e-05 -197.088396610469 41.0544197164952 -4.80066209610269 2.04745281008375e-06 PHF13 other 2.8587556924985e-12 0.0256279668238184 0.56839718339553 4.0152845950113 -4.80066209610269 0.180443265441034 51.4570521606385 158.22154461806 0.32522152583489 0.745139151350604 -368.213481986103 258.392517681487 -1.42501603873835 0.154729198691262 ERRFI1 other 1 1 1 0.32522152583489 -1.42501603873835 3.95933165237821e-23 701.44282805699 162.313242293572 4.32153789885058 1.84431762330064e-05 -1678.58094914919 265.074692770344 -6.33248286211724 5.07492538500148e-10 PARK7 other 4.97292055538704e-19 7.15513730031359e-06 0.162539712141485 4.32153789885058 -6.33248286211724 0.000128671372914024 517.246554253086 537.303629723337 0.962670872927885 0.336142798134698 -4406.71115375814 1285.96149770597 -3.42678312034947 0.000657216941271565 KIAA1324 other 0.690193244310822 1 1 0.962670872927885 -3.42678312034947 0.427903260770632 11.4022773510862 18.4587205404845 0.617717643326263 0.537021405683171 -20.9469832156356 29.8329560863765 -0.702142394303367 0.482892334748762 OPRD1 other 1 1 1 0.617717643326263 -0.702142394303367 3.93694217414014e-13 128.682442408822 25.0954059204016 5.12772906790116 4.10067875538824e-07 -186.117243218185 57.0904825680565 -3.26003976225492 0.00118455619173655 AMPD2 other 3.77749601608746e-09 1 0.0040473699315682 5.12772906790116 -3.26003976225492 3.93099847147265e-17 228.078059926072 59.7491053082121 3.81726318326518 0.000150538377579198 -517.92506321814 96.7633101849137 -5.35249426904051 1.28365011366367e-07 SRSF4 other 4.33707061357578e-13 0.00169056719969505 1 3.81726318326518 -5.35249426904051 2.20444874491961e-09 72.5017626010527 18.4438210010453 3.93095132494204 9.55950002143205e-05 -78.3549605349724 29.8699579890271 -2.62320290385934 0.00895645834533192 MECR other 1.7741403499113e-05 1 0.791622196774788 3.93095132494204 -2.62320290385934 0.0822056053619415 -3.02778794896437 22.9428480839321 -0.131970884254987 0.895056116234216 -103.682435007568 49.7665325405977 -2.08337671351701 0.0376831912580018 KCNC4 other 1 1 1 -0.131970884254987 -2.08337671351701 8.30418958513917e-08 341.444202335305 62.4933618298206 5.463687539568 7.12419584573883e-08 -682.867441999753 443.744108359648 -1.53887663889004 0.124419070287379 EDEM3 other 0.000603880666631321 1 0.000734077139944929 5.463687539568 -1.53887663889004 7.8289861009249e-22 226.144635420009 25.6125436717554 8.82944850453854 1.4300909762951e-17 -66.3088274459209 57.7044724891705 -1.14911071162405 0.251013457589541 WDR77 essential 9.61712652637614e-18 1 1.91017251703736e-13 8.82944850453854 -1.14911071162405 3.75248375060761e-26 384.607191924908 54.1646834352891 7.10070044781856 3.88396842638237e-12 -629.962457989394 122.03178744105 -5.16228165791401 3.42213986122348e-07 ATP5F1 essential 4.92626066779767e-22 0.00442961783636767 4.65843173060302e-08 7.10070044781856 -5.16228165791401 2.24656245391964e-14 170.763024957473 33.4433748500329 5.10603447538445 4.55167059076622e-07 -272.031049174925 75.1910109309808 -3.61786662802855 0.000324618019379018 RAP1A other 2.26318701607865e-10 1 0.00447747836013673 5.10603447538445 -3.61786662802855 4.67679789642156e-21 742.106576515735 92.3315481144284 8.03741074064985 5.83450824382079e-15 -382.50248560774 171.08165915756 -2.2357889647041 0.0257741746823799 HDAC1 other 5.6579900950908e-17 1 7.45475118312982e-11 8.03741074064985 -2.2357889647041 1.27099063439579e-15 745.420904600824 106.668682385429 6.9881889222872 8.17586183694444e-12 -360.906681252965 233.654628438111 -1.54461601580711 0.123020672238419 CAPZA1 other 1.33924283146285e-11 1 9.72355248267803e-08 6.9881889222872 -1.54461601580711 4.17317256722348e-20 107.077464789808 18.3710276167632 5.82860507444351 9.62984692019363e-09 -165.098732747601 34.1725335790383 -4.83132842245194 1.77042114961746e-06 S100PBP other 4.95146925101066e-16 0.0222258671122976 0.000103126030668354 5.82860507444351 -4.83132842245194 6.73371811691995e-06 105.166961981465 29.0843672567623 3.615927451783 0.000327317507068042 -84.887268152763 54.0907449678952 -1.5693492149747 0.117152340223793 RNF19B other 0.0415201059089284 1 1 3.615927451783 -1.5693492149747 3.8385781786423e-33 474.589735471341 36.8001312086917 12.8964142214593 2.8822691251698e-33 684.035088838939 382.007966242926 1.79063042995273 0.0739264635413741 SCAMP3 other 5.40279878643903e-29 1 4.28506950838994e-29 12.8964142214593 1.79063042995273 1.40988173365264e-05 31.5127114204371 15.7896099318204 1.99578783494394 0.0464569829724084 -91.9502115290283 29.4082374309386 -3.12668216668752 0.00186274518371158 TRIM62 other 0.0846492992885042 1 1 1.99578783494394 -3.12668216668752 0.0188661257940791 12.4842984169214 4.78849300048891 2.6071455916604 0.00938291863798194 17.8905702599776 8.5770537207735 2.08586431219929 0.037460580213956 DLGAP3 other 1 1 1 2.6071455916604 2.08586431219929 2.07131546033212e-11 798.620473905815 144.148634396913 5.54025695246487 4.72539538365472e-08 -533.83143271646 275.176265722642 -1.93996175983624 0.0529046327171609 SFPQ other 1.84864904834642e-07 1 0.000491535627807764 5.54025695246487 -1.93996175983624 0.0599350005999853 64.4668337320722 27.7801955512737 2.3206040293376 0.0206777940420669 -61.0921931078353 165.114402133225 -0.369999178257886 0.711527368635424 RHOU other 1 1 1 2.3206040293376 -0.369999178257886 5.49506500415224e-16 238.597666288284 27.5553546033379 8.65884942229639 6.17654905135128e-17 20.6553862280876 274.125236094183 0.075350181261644 0.93996541314782 GON4L other 5.85773929442629e-12 1 8.17528032436855e-13 8.65884942229639 0.075350181261644 3.30419539006012e-11 386.455160338748 54.5593868993031 7.08320203546282 4.46643399480781e-12 -380.588677556705 517.245013382893 -0.735799606974602 0.462175725514818 ARHGEF2 other 2.92024788573513e-07 1 5.34944799558132e-08 7.08320203546282 -0.735799606974602 1.12230237631405e-10 215.625599299439 31.3642803799557 6.8748779403605 1.72833621020462e-11 189.4098108464 282.874966165479 0.669588452502359 0.503407970552009 LAMTOR2 essential 9.65404504105349e-07 1 2.03615288924207e-07 6.8748779403605 0.669588452502359 3.681146894165e-07 198.151454250548 36.0038028709399 5.50362568534346 5.75195799655696e-08 -114.468312516393 323.723869006007 -0.353598617450939 0.723777462266839 MEF2D other 0.00255397971517167 1 0.000595672770123439 5.50362568534346 -0.353598617450939 7.08719724021821e-16 437.695488163112 55.6422452064941 7.86624419159901 2.00384636203868e-14 -90.4848655606263 122.458570521772 -0.73890186023802 0.460287633028934 DOCK7 other 7.52943834800783e-12 1 2.53246103234448e-10 7.86624419159901 -0.73890186023802 1.2024011877842e-06 298.125197736386 72.4675357868291 4.1139138305096 4.49129359205013e-05 -98.1633138539568 116.900459339776 -0.839717092715958 0.401435226743853 SRM other 0.0079659078690703 1 0.383197169273717 4.1139138305096 -0.839717092715958 0.00123478655431179 115.123845237516 58.7436595346922 1.95976631604858 0.0505342046554012 -156.26301560579 93.6524082052336 -1.66854241765305 0.0957845596930248 FBXO2 other 1 1 1 1.95976631604858 -1.66854241765305 1.26370241987917e-08 50.7702628883281 20.9801934396387 2.41991395524532 0.0158514710463184 -120.285843588713 33.5511014203059 -3.58515334807796 0.00036724512866086 FBXO6 other 9.70776198951182e-05 1 1 2.41991395524532 -3.58515334807796 0.000835620430719336 294.390494628237 88.389563516393 3.33060242540555 0.000925581683777256 -984.504884645764 628.837370464466 -1.56559538425428 0.118027006911392 C1orf21 other 1 1 1 3.33060242540555 -1.56559538425428 7.06453815425439e-12 26.12405219538 3.60541031561392 7.24579171536864 1.4930686164536e-12 -16.4541967906895 25.7252665025324 -0.63961229669165 0.522695934491953 SWT1 other 6.45628141917309e-08 1 1.80915124255682e-08 7.24579171536864 -0.63961229669165 2.42953497662038e-06 195.461083931309 47.5528006904541 4.11040109295912 4.55924991800625e-05 -41.2005278062519 76.4848837636534 -0.538675432044403 0.590331180960698 MAD2L2 essential 0.015672930134178 1 0.388676055510033 4.11040109295912 -0.538675432044403 0.00096042503035072 55.6335263424439 15.9409016683892 3.48998616889817 0.000522742176930566 -3.09565491985942 31.9951550617692 -0.0967538651987468 0.922957960443435 DNAJC6 other 1 1 1 3.48998616889817 -0.0967538651987468 0.625827995696399 -26.0416139702309 42.0713071286109 -0.618987517802152 0.536186585909909 -77.0025632881821 84.4329531973143 -0.911996564993198 0.362178991825418 LEPR other 1 1 1 -0.618987517802152 -0.911996564993198 3.89059423434274e-06 271.454322322574 55.0787272607698 4.92847848566608 1.10464682726413e-06 571.998269191148 393.00035667985 1.45546501286541 0.146122731760506 IVNS1ABP other 0.0245691025898744 1 0.0106057141885629 4.92847848566608 1.45546501286541 1.97578186234016e-23 225.361408608235 94.1889319943546 2.39265276541985 0.0170665371289887 -1145.2012394053 149.96069411388 -7.63667603815999 1.01436613111206e-13 MFN2 essential 2.49205366296965e-19 1.50663801454074e-09 1 2.39265276541985 -7.63667603815999 2.71488764955064e-05 94.041468804363 21.5939321065725 4.35499511345319 1.60227738941267e-05 -183.414983577708 146.229120073411 -1.25429862045008 0.210294846320877 PRG4 other 0.158169354462821 1 0.141897685606386 4.35499511345319 -1.25429862045008 0.000176127793927518 92.6765984400623 28.1759628931031 3.28920785393097 0.00106968486317881 -21.4815603050797 44.7497704487293 -0.480037329570026 0.631393804116005 MIIP other 0.925727684883036 1 1 3.28920785393097 -0.480037329570026 7.80723277576429e-14 357.292489685411 45.034553910378 7.9337410646156 1.22219581994379e-14 484.183771823705 320.966422121624 1.50851845692517 0.132003485155414 SMG7 essential 7.71276525917754e-10 1 1.55279978923858e-10 7.9337410646156 1.50851845692517 0.0161856032239443 2.72895234674845 11.1284109926811 0.245223900208505 0.806375720675072 228.617028619416 79.3134593345371 2.88244934135491 0.00410220637600317 NCF2 other 1 1 1 0.245223900208505 2.88244934135491 1.97348620448793e-07 46.7062355552946 33.314772360079 1.40196772322126 0.161499431691658 -318.102705140305 67.7409382023631 -4.6958709693396 3.37092977344682e-06 SLC35D1 other 0.00139643883829566 0.041772561752553 1 1.40196772322126 -4.6958709693396 0.0905795353392858 34.0924197256516 16.0571181001067 2.12319667284661 0.0342063345571323 76.5283972127361 110.653987214889 0.69160090059944 0.48949488381906 PLA2G4A other 1 1 1 2.12319667284661 0.69160090059944 2.31237290934359e-05 26.7021248535994 39.0619301440026 0.683584368595242 0.494531954098085 -310.819165510908 75.8091419988028 -4.10002220465464 4.76956693476594e-05 GADD45A other 0.135574423674815 0.551171154981552 1 0.683584368595242 -4.10002220465464 0.00136629559261974 -49.1821736208269 104.131394771204 -0.472308795333909 0.636897558434282 -724.271367940788 203.203439026799 -3.5642672752466 0.000397272359585992 WLS other 1 1 1 -0.472308795333909 -3.5642672752466 1.77435448403125e-14 48.2957734855231 54.740753878724 0.882263579937545 0.378024676057874 -559.13952401262 87.0391494717729 -6.42400031946487 2.90358307826775e-10 PRDM2 other 1.79546930239122e-10 4.11495793852105e-06 1 0.882263579937545 -6.42400031946487 0.43550135549298 59.7873273985372 55.5458900984005 1.07635915623321 0.282259151773488 310.96700687631 393.919838325104 0.789416974271977 0.430223355085961 RGS2 other 1 1 1 1.07635915623321 0.789416974271977 5.38136319568694e-11 193.994255474738 27.983653425635 6.93241345309923 1.21402408925158e-11 -133.954098652057 197.738764158838 -0.677429634102777 0.49843067657978 TROVE2 other 4.70438770566952e-07 1 1.4375259240828e-07 6.93241345309923 -0.677429634102777 0.722816269551411 -24.9467370583513 37.7364250733555 -0.661078441051518 0.50884395142507 -60.5535096414777 88.3243695043028 -0.685581000819121 0.493271573799423 AMPD1 other 1 1 1 -0.661078441051518 -0.685581000819121 1.03565342506278e-17 177.133322433328 19.3609359188371 9.14900618316634 1.25307807180724e-18 -14.5738318963975 137.303709301629 -0.106143031171734 0.915509260223685 UCHL5 other 1.16003540141282e-13 1 1.6972942482629e-14 9.14900618316634 -0.106143031171734 2.28409285449826e-28 147.99338957228 17.0517406827231 8.67907812615441 4.73912260504345e-17 -167.410985775152 40.0173999535467 -4.18345484637901 3.35156787461697e-05 BCAS2 essential 3.07667307500915e-24 0.3906922671441 6.28549831106913e-13 8.67907812615441 -4.18345484637901 2.46188573080747e-10 412.743526752417 103.770428479809 3.97746769285749 7.91846918175126e-05 -758.402547439813 202.579749512221 -3.74372339419868 0.000200841889972396 SRSF11 essential 2.08595577971317e-06 1 0.660479514449873 3.97746769285749 -3.74372339419868 0.369895084332661 10.3748967460639 10.27154331125 1.01006211351907 0.312918739879349 -11.3355195397047 20.0656140487124 -0.564922633924185 0.572361425665609 CTH other 1 1 1 1.01006211351907 -0.564922633924185 0.0815711354881161 12.9980336260725 5.95334758207388 2.18331509237103 0.0294384317714427 6.80393148966305 9.6334442577656 0.706282333463272 0.480314394048711 AGMAT other 1 1 1 2.18331509237103 0.706282333463272 0.220770512678414 -22.5272154320942 48.3691598547948 -0.465735098557041 0.641592564051962 -450.959448122185 263.909407802162 -1.70876609469051 0.0880678353313588 OLFML3 other 1 1 1 -0.465735098557041 -1.70876609469051 0.236020409657371 -2.12626490577184 2.88793009426797 -0.736259132446487 0.461891541028496 -9.83951834272511 5.80095422725065 -1.6961896193738 0.0904241951917554 TNNI3K other 1 1 1 -0.736259132446487 -1.6961896193738 0.228155978703911 0.72233195383207 0.659153017685209 1.09584866404576 0.273649365785697 -5.67322244651997 4.62881332468142 -1.22563215420022 0.220888751840485 CFHR3 other 1 1 1 1.09584866404576 -1.22563215420022 1.56230841258566e-13 66.8228391954297 44.8560737451651 1.48971663402957 0.136878283407389 -410.369035289312 71.1116809314734 -5.77076831701902 1.32611334715009e-08 PLEKHM2 other 1.52621908825493e-09 0.000180709465816143 1 1.48971663402957 -5.77076831701902 5.83091953148487e-06 73.6571748846376 43.9882655234269 1.67447327163672 0.0946134339805654 -331.675880484595 88.5428081462577 -3.74593812223261 0.000198938131512266 CRYZ other 0.0361517010952062 1 1 1.67447327163672 -3.74593812223261 4.33151794953263e-196 339.940775733692 7.07797437330138 48.0279749268339 1.92970260486913e-197 204.141654966147 38.3010826819491 5.32991865168232 1.44386230795959e-07 PHTF1 other 6.79095384127726e-192 0.00189853454873607 3.02538774391382e-193 48.0279749268339 5.32991865168232 3.64098729443361e-13 83.1379718649996 19.9863043685569 4.15974711141671 3.71215108725164e-05 -119.843003360847 33.0758105384555 -3.62328243540736 0.000318679188975638 ZBTB17 essential 3.50044518486847e-09 1 0.319170750481896 4.15974711141671 -3.62328243540736 4.28842320163243e-18 47.9451715128467 5.59731693201378 8.56574178221442 1.14961885635473e-16 -16.9678102444788 18.4098702003017 -0.921669194832276 0.357116582974983 CD58 other 4.85020664104628e-14 1 1.51370314816227e-12 8.56574178221442 -0.921669194832276 0.170229028258895 0.926868148171458 2.1968414896939 0.421909433393215 0.673260605595693 -6.38445650136084 4.20316353122337 -1.51896457369161 0.129362123583231 TFAP2E other 1 1 1 0.421909433393215 -1.51896457369161 0.0702323469722947 39.2362782010713 17.3483390454065 2.26167347193161 0.0241173919309974 12.1629572326931 57.152705894618 0.212815072222826 0.831552119484303 CD2 other 1 1 1 2.26167347193161 0.212815072222826 1.52791578705341e-23 152.144961095488 15.0004790527107 10.1426734813509 3.14592791867072e-22 -31.0992671399449 51.7602848297631 -0.600832612150972 0.548205934253378 TTF2 essential 1.93174392957163e-19 1 4.41059094197635e-18 10.1426734813509 -0.600832612150972 0.216224402788442 -4.53070119808349 3.91396271951785 -1.15757392769485 0.247547817683084 -39.0550529770602 28.4578044254752 -1.37238461524103 0.170511391819819 NR5A2 other 1 1 1 -1.15757392769485 -1.37238461524103 0.000560403852143245 18.9751197187078 6.29092717701729 3.01626758421712 0.00267889878424591 115.715070404558 44.8365639518111 2.58081931811111 0.0101178905017785 KIF21B other 1 1 1 3.01626758421712 2.58081931811111 1.20679159510752e-19 552.054126293391 57.8439088052388 9.54385928779752 4.58215068425932e-20 -608.653134554806 414.094389440789 -1.46984153872927 0.142181705268654 TMEM9 other 1.41966963248448e-15 1 6.30733041688295e-16 9.54385928779752 -1.46984153872927 8.41288928628527e-17 163.511964799836 25.7372070728123 6.35313553398585 4.54662957911297e-10 -177.006908392099 50.7431693467188 -3.48829035850408 0.000526534530203852 ADPRHL2 other 9.18603381169489e-13 1 5.12950749115525e-06 6.35313553398585 -3.48829035850408 1.7664908860875e-12 273.449135431103 73.4929800317784 3.72075176857522 0.000219435132923896 -684.982895169038 145.875468765236 -4.69566885348908 3.37413363360309e-06 MAP7D1 other 1.65431871482094e-08 0.0418088898539759 1 3.72075176857522 -4.69566885348908 5.14926491971095e-14 73.8165793071941 11.788151241594 6.261930119011 8.03534705401241e-10 -150.267475502238 43.227804468662 -3.47617644128039 0.000551672859557739 WARS2 other 5.1199141096686e-10 1 8.97869679815346e-06 6.261930119011 -3.47617644128039 0.697610010036976 -8.03049209873595 14.0111293436387 -0.573150950346622 0.566796105308243 -39.2007265705391 53.1235688287418 -0.737915908792071 0.460906278189305 HAO2 other 1 1 1 -0.573150950346622 -0.737915908792071 6.76262502643276e-09 23.334160659187 15.5163471692759 1.50384368206141 0.13320407324106 -158.458758998446 31.2627210115437 -5.06861699402092 5.50708976970325e-07 OSCP1 other 5.29175408318363e-05 0.0070744075181608 1 1.50384368206141 -5.06861699402092 2.74275284717704e-13 417.579921141015 63.748571035759 6.5504201012879 1.33515856433611e-10 -201.080349137591 128.649583009603 -1.56300816865128 0.118634333488847 MRPS15 other 2.65279055378963e-09 1 1.53236148428855e-06 6.5504201012879 -1.56300816865128 1.32006973882824e-14 78.5339668887782 9.74199521206833 8.0613842625883 4.83636523841276e-15 -77.3284159119323 59.4124251215387 -1.30155292859605 0.193621184709043 EXOC8 other 1.34237891741444e-10 1 6.18812932254913e-11 8.0613842625883 -1.30155292859605 2.11056463555479e-33 283.873685678223 21.7788053223081 13.034401174772 5.55727185818976e-34 -165.839385020318 132.819983204804 -1.24860266519232 0.212348493239462 GNPAT other 2.97610719259581e-29 1 8.2820022502602e-30 13.034401174772 -1.24860266519232 3.68170678150329e-19 215.068828470885 22.742390082705 9.45673817434162 9.392620303299e-20 -159.402681937673 137.243991506476 -1.16145472153622 0.245965448220546 TSNAX other 4.27482974400347e-15 1 1.28819787459746e-15 9.45673817434162 -1.16145472153622 3.34299276278675e-15 87.2373430498989 13.3392356608447 6.53990567885165 1.4272149486425e-10 -81.0815513314547 27.6361277788144 -2.93389696199086 0.00348934507281631 C1orf109 essential 3.47403807908799e-11 1 1.63615921712376e-06 6.53990567885165 -2.93389696199086 6.00024314374727e-12 178.994055616264 31.7264597366911 5.64179101928793 2.72109726755719e-08 -179.748118604437 68.3799858325123 -2.62866563097434 0.00881659502150967 RRAGC other 5.49922284124438e-08 1 0.000286232221574341 5.64179101928793 -2.62866563097434 1.6046927253695e-46 180.33603697252 11.2607821346887 16.0145214440298 1.47119940378614e-47 -8.65231811248949 70.8414429464205 -0.122136390121719 0.902836189661608 TBCE essential 2.40479251823874e-42 1 2.2474042092237e-43 16.0145214440298 -0.122136390121719 0.134950674084809 -90.3516634336463 79.404406072234 -1.137867127316 0.255676861279931 -839.146011314615 486.849409527622 -1.72362540632188 0.0853436650009138 NID1 other 1 1 1 -1.137867127316 -1.72362540632188 3.00073243621772e-11 531.303989796589 83.305558069672 6.37777360968204 3.83746842950438e-10 -1464.26840617219 519.211869146348 -2.82017514079491 0.00497451278378365 LGALS8 other 2.65714857227079e-07 1 4.34132803429831e-06 6.37777360968204 -2.82017514079491 1.9231295736418e-12 179.245057306685 24.1105739640776 7.43429242181221 4.12935351987862e-13 -124.200129940935 150.189874411348 -0.826954083474155 0.408626999177994 MTR other 1.79774152544036e-08 1 5.06300035072317e-09 7.43429242181221 -0.826954083474155 5.69924889960611e-07 113.020194781764 21.3582807583521 5.29163353832063 1.76297569965161e-07 21.3206772909223 47.073664640206 0.452921552929452 0.650786479773789 BMP8B other 0.00388574789975144 1 0.00177461133926931 5.29163353832063 0.452921552929452 5.23036733360417e-06 72.5020537066201 19.5615405957004 3.70635704033228 0.000231870755781829 -87.6754010767319 43.1136481567079 -2.03358808231799 0.0424797317892615 MYCL other 0.0325799581210204 1 1 3.70635704033228 -2.03358808231799 0.000896546842658982 134.897676917322 36.2902149587596 3.71719145424243 0.000222271508144941 180.34890826701 217.617301727983 0.82874342634963 0.407612399632463 SIPA1L2 other 1 1 1 3.71719145424243 0.82874342634963 2.58186356704404e-09 133.77219893326 26.6268184651173 5.02396480858235 6.89104537052638e-07 -127.806975736499 57.8043463495003 -2.21102709065758 0.0274521972180202 RLF other 2.06858908991568e-05 1 0.00669878520468869 5.02396480858235 -2.21102709065758 8.51553235631263e-07 121.535124833961 22.8201985535821 5.3257698239827 1.47452421709692e-07 -22.0564575883541 140.327476027991 -0.157178467201637 0.875162623962794 KMO other 0.00572669550962024 1 0.00149000672137644 5.3257698239827 -0.157178467201637 3.0079344308068e-07 5.03176926793513 1.95595448812682 2.57253903323382 0.0103610855932739 -16.1857731331846 4.18912839350374 -3.86375675624662 0.000125194726861749 ZNF684 other 0.00209803426548774 1 1 2.57253903323382 -3.86375675624662 6.41215304326396e-08 57.6111486354872 10.0431125814222 5.73638383204593 1.6167482267224e-08 15.9516166597435 21.4882347302721 0.742341884290346 0.458204797785853 KCNQ4 other 0.000470523790314709 1 0.00017163399174885 5.73638383204593 0.742341884290346 0.00173604729317972 38.7695375862184 15.6931335439354 2.47047777154746 0.0138004767180853 -56.751446552931 33.6104708524707 -1.68850495436481 0.0918906084359515 RIMS3 other 1 1 1 2.47047777154746 -1.68850495436481 1.84749409017158e-05 198.331335229288 42.1958164462168 4.70026064034295 3.29639851076554e-06 151.707195834515 267.856656574889 0.56637455934234 0.571372760719611 AKT3 og 0.109667249192585 1 0.0306894701352272 4.70026064034295 0.56637455934234 1.45679130803807e-13 223.131774450249 28.3603969642514 7.86772395081454 1.97113799926235e-14 210.942480236768 255.85610535187 0.824457481468603 0.410042337455005 ETV3 other 1.42415918273802e-09 1 2.49191265866746e-10 7.86772395081454 0.824457481468603 1.43020743747142e-07 187.996080287782 57.4541257502561 3.27210757857445 0.00113557057392298 -361.23876880235 115.589148895626 -3.12519619924306 0.00187219014147885 ACADM other 0.00102388550448579 1 1 3.27210757857445 -3.12519619924306 0.0241861480783015 144.395479079278 52.8649984430443 2.7314004224335 0.00651323850635865 91.6977432983035 105.102535143427 0.872459861916455 0.38334603755558 ST6GALNAC5 other 1 1 1 2.7314004224335 0.872459861916455 0.134416582032756 -1.80971906969864 2.10045093854678 -0.861585974938655 0.38929710499421 38.3452055248983 20.9760159252085 1.82804998154182 0.0680925908511308 SLAMF1 other 1 1 1 -0.861585974938655 1.82804998154182 0.335961089468744 -13.2061704589279 9.34337342239455 -1.41342637845072 0.158104447312419 42.9312583652824 93.3986483488192 0.459656099143379 0.645947400159631 CD48 other 1 1 1 -1.41342637845072 0.459656099143379 0.0220105886032107 170.055973690462 83.8786330743998 2.02740516216596 0.0431116273415745 -140.563313494317 161.610726162842 -0.869764754058976 0.384815417404977 ADGRL2 other 1 1 1 2.02740516216596 -0.869764754058976 0.00257005349895476 1116.59074918725 332.889181678815 3.35424162346191 0.000850865950398253 1350.20631916198 531.8595456897 2.53865203718601 0.0114035909177335 PADI2 other 1 1 1 3.35424162346191 2.53865203718601 1.33652866307886e-23 277.082397605856 43.9755958656955 6.30082190249531 6.09439029297487e-10 -283.465423426988 69.7721484445932 -4.06273032644381 5.56027175640799e-05 SDHB ts 1.69070875879476e-19 0.639320046551791 6.84278142095218e-06 6.30082190249531 -4.06273032644381 0.460822415278031 -114.624482612006 96.7947622785711 -1.18420129264971 0.236848642293302 -146.633749349708 153.590558949057 -0.954705486802374 0.340149136646561 MFAP2 other 1 1 1 -1.18420129264971 -0.954705486802374 4.77296463417533e-24 109.74217137563 21.9041354071594 5.01011198733551 7.37018891353817e-07 -273.764222822417 41.5972194138422 -6.58131064239639 1.10021243585753e-10 RPF1 essential 6.07932505454912e-20 1.5715434433789e-06 0.00714982026502338 5.01011198733551 -6.58131064239639 3.98887932744182e-21 781.360468387169 77.6817628891611 10.0584801287535 6.15406945995055e-22 -811.792069212232 608.584738915413 -1.33390145579228 0.18279638141879 KDM5B other 4.83133064139753e-17 1 8.60400451195687e-18 10.0584801287535 -1.33390145579228 1.03441630521908e-17 447.895724920304 49.0220019919271 9.13662654972888 1.32002089931729e-18 -679.233148934464 455.984130778697 -1.48959821863651 0.136918073855316 UAP1 other 1.15875314510642e-13 1 1.78730829767561e-14 9.13662654972888 -1.48959821863651 0.697397802373248 32.9806312219859 39.6416342128944 0.831969515809168 0.405789203591651 37.2100400954034 63.7426992551009 0.583753755806407 0.559626622884807 ACTL8 other 1 1 1 0.831969515809168 0.583753755806407 8.36893323182938e-09 4.70629410243134 26.7620813140913 0.175856804528626 0.860471882410682 -279.890899615848 50.7641334083124 -5.51355614336199 5.44013693263957e-08 CTBS other 6.50433490777779e-05 0.000726367083246035 1 0.175856804528626 -5.51355614336199 0.221784086914613 -24.2089154336674 18.7938787228864 -1.28812768192373 0.198258356233622 -196.090579398557 174.478484369196 -1.12386682006951 0.26157355275461 RGS4 other 1 1 1 -1.28812768192373 -1.12386682006951 1.84722282275962e-28 252.424115409646 21.0766019585181 11.976509112164 1.70785618714949e-29 -153.482492912186 165.119289013314 -0.929524913953634 0.353030150671414 KLHL12 other 2.49024108736224e-24 1 2.50508345531087e-25 11.976509112164 -0.929524913953634 0.363426263583219 17.7468552882385 53.0229574918675 0.334701346882818 0.737978921307338 -83.1584537164456 83.8712618952012 -0.991501163060522 0.321880112196073 IGSF21 other 1 1 1 0.334701346882818 -0.991501163060522 7.29964516317352e-17 301.36681357803 39.6527851359978 7.60014239969342 1.3097674660974e-13 -80.7827106862812 75.6095848004375 -1.06841891672197 0.285807205545919 SSX2IP other 7.98508184399551e-13 1 1.62633826265314e-09 7.60014239969342 -1.06841891672197 2.57476213491084e-05 215.656233339372 54.4123616820863 3.96336837205084 8.37932866133666e-05 -63.8809031462168 104.033449089189 -0.614041961556529 0.539445239423261 ZNHIT6 essential 0.150390188634783 1 0.69741152448305 3.96336837205084 -0.614041961556529 0.551200628704513 11.1296417686551 13.9044576917908 0.800436954490221 0.423805177941578 24.5667760733207 23.4032153600292 1.04971798513117 0.294311344013685 PLA2G2D other 1 1 1 0.800436954490221 1.04971798513117 7.55823169758813e-34 165.153097661809 12.4767971846598 13.2368183290552 7.43778090143709e-35 47.9756453173407 114.377593270614 0.419449683679145 0.675053717695772 RBBP5 essential 1.06941420289174e-29 1 1.11083257762963e-30 13.2368183290552 0.419449683679145 0.0017958904972065 93.2266505772828 70.403721833938 1.32417219074266 0.186015555565967 -369.786771007934 146.143711828191 -2.53029546315796 0.0116845204660339 GBP3 other 1 1 1 1.32417219074266 -2.53029546315796 1.03536350313731e-05 727.714063949423 151.026235931367 4.81846123927852 1.89258659740715e-06 740.186087548106 313.601179394813 2.36027839237249 0.0186232219658023 GBP1 other 0.0628776255455287 1 0.0179095469712639 4.81846123927852 2.36027839237249 1.44978671007465e-19 212.509326015726 63.8264138344714 3.32948873748182 0.000928774004831275 -628.606467900157 104.64795594673 -6.00686809611594 3.45577757125501e-09 PINK1-AS other 1.70190461895663e-15 4.78245058085981e-05 1 3.32948873748182 -6.00686809611594 3.59923777064216e-06 -4.10580050023577 2.17517033417113 -1.88757654319533 0.0596129007403567 -17.9688527528543 3.59864844968426 -4.99322259567502 8.00125935766081e-07 KIF17 other 0.0228083697525593 0.0102072065625679 1 -1.88757654319533 -4.99322259567502 0.000423768816474276 46.9722159541816 12.9554802137905 3.62566382558186 0.000315407335695438 172.600306554536 118.990116543949 1.45054321793849 0.147485553569524 CDK18 other 1 1 1 3.62566382558186 1.45054321793849 2.46441003599591e-13 80.1126924460152 14.8445656596943 5.39676904549222 1.01735060287301e-07 742.162668522196 135.743456247265 5.46739186580237 6.98990072998311e-08 RAB29 other 2.38850620688723e-09 0.000929936393116952 0.0010382062902319 5.39676904549222 5.46739186580237 3.19667795283262e-10 463.39676882442 310.021111439561 1.49472649353675 0.1355645992517 -2501.35291798504 515.918033183709 -4.84835333734952 1.62618721500593e-06 ECE1 other 2.68840615833223e-06 0.0204476780414846 1 1.49472649353675 -4.84835333734952 5.96006286321818e-19 86.9981552890189 41.0791005976617 2.11782035203495 0.034642400775655 -441.251714389247 65.0397837943336 -6.7843355043208 3.04724805176557e-11 HMGCL other 6.87970056301274e-15 4.39321751623043e-07 1 2.11782035203495 -6.7843355043208 3.84162212073339e-10 281.614629545708 60.294077379367 4.67068478009548 3.78561932767708e-06 -157.486412180558 95.4625028245159 -1.64972012592271 0.0995763824513292 GALE other 3.21659020169006e-06 1 0.0351267617415156 4.67068478009548 -1.64972012592271 0.426183995720959 59.6173063922309 61.2761904851155 0.972927754161095 0.331020822005052 -22.6960059050184 96.9928746122693 -0.23399663115199 0.815075466086799 ID3 other 1 1 1 0.972927754161095 -0.23399663115199 0.257092506403043 -12.0537421140938 7.33964557585071 -1.64227849826341 0.101132244891327 8.52924807771568 57.6975474979508 0.147826873889546 0.882536264358454 CR2 other 1 1 1 -1.64227849826341 0.147826873889546 2.69626259277259e-13 1245.62963059291 162.640689632483 7.65878227279803 8.80267062404131e-14 -1674.79778939549 1256.8133405368 -1.33257480277872 0.183236536496397 CD46 other 2.60863405850748e-09 1 1.09734091999299e-09 7.65878227279803 -1.33257480277872 3.31034953527513e-15 185.721576920654 22.4882388748234 8.2586092203324 1.25073713983351e-15 313.227024262182 271.471286558105 1.15381272263997 0.249112128243127 PRPF3 essential 3.44077730696497e-11 1 1.61632760580685e-11 8.2586092203324 1.15381272263997 3.62497908996978e-26 872.076629241543 77.2943327258902 11.2825429560819 1.55787827024682e-26 1217.73359585257 940.491976745967 1.29478360896373 0.195975077068166 APH1A other 4.76032254094831e-22 1 2.25175725181475e-22 11.2825429560819 1.29478360896373 9.04368937208342e-06 47.7673890744198 33.067395691581 1.44454645052623 0.149165297982702 -315.214803109441 79.0285592004119 -3.98861887776638 7.56201992456334e-05 P3H1 other 0.0552298109953134 0.860028526020588 1 1.44454645052623 -3.98861887776638 2.8947353579896e-05 852.746186093688 193.295746585581 4.41161381539317 1.23861428826316e-05 24.5812391385861 464.528393450657 0.052916548235059 0.957817932775783 SLC2A1 other 0.168155176945616 1 0.110744503513609 4.41161381539317 0.052916548235059 1.10638215887847e-13 508.386366980569 67.7841602155473 7.50007620311216 2.63129042501503e-13 -9.10525847695708 152.659419060849 -0.0596442625877398 0.952460989877898 CDC20 essential 1.08624600358688e-09 1 3.24595986829854e-09 7.50007620311216 -0.0596442625877398 0.0278457338120311 0.734210050446032 12.9727708677788 0.0565962397647544 0.954887687422005 -71.1823053322839 28.2780449128903 -2.5172286680907 0.0121155276830423 ARTN other 1 1 1 0.0565962397647544 -2.5172286680907 3.54149657766935e-22 192.067788497445 27.9603645444792 6.86928770874589 1.77583364602881e-11 -312.887711821251 60.9480004255209 -5.13368296969157 3.96691773867782e-07 IPO13 essential 4.37728976999931e-18 0.00512208418418079 2.09086653483432e-07 6.86928770874589 -5.13368296969157 5.73855972575417e-09 599.430777852948 131.995867098903 4.54128444342731 6.89562283857757e-06 -746.146368682124 287.724580676092 -2.59326598696864 0.00976378831465307 ATP6V0B essential 4.5076386645799e-05 1 0.0628811846649888 4.54128444342731 -2.59326598696864 1.17490897736906e-17 365.321647691427 53.9461318002651 6.77197114047075 3.31396495746109e-11 -423.322210786881 117.591773837118 -3.5999304796035 0.000347508771790567 B4GALT2 other 1.3141356911873e-13 1 3.87137386330605e-07 6.77197114047075 -3.5999304796035 6.37175003856853e-24 322.742637768655 39.7606382100708 8.11713926882866 3.20414963118682e-15 -361.753966708596 87.0007976703252 -4.15805344773276 3.72863679429366e-05 ERI3 other 8.0984942990206e-20 0.433491313704581 4.11220563666516e-11 8.11713926882866 -4.15805344773276 0.340527174938715 -3.90389501960218 6.08954193200373 -0.641081884843451 0.521739462473547 -18.75331475297 12.8581750516917 -1.45847405853311 0.145287017784329 PTCH2 other 1 1 1 -0.641081884843451 -1.45847405853311 6.96218209306365e-09 159.85438958913 97.3915628229342 1.64135767982036 0.10130115620794 -1026.54445295416 205.142090084045 -5.0040654871635 7.59064211123341e-07 AKR1A1 other 5.44373017856647e-05 0.00969552716867843 1 1.64135767982036 -5.0040654871635 1.99974549397997e-16 3110.89020528011 430.621054735261 7.22419438406847 1.71151576474707e-12 -1845.27707498071 907.044723814464 -2.03438378123256 0.0423974248453896 PRDX1 other 2.15992510804776e-12 1 2.07178983322633e-08 7.22419438406847 -2.03438378123256 0.000108959033310589 79.9405533160156 127.806727143389 0.625480012693922 0.531919330252837 -967.04467795576 259.314463108411 -3.72923540925472 0.000212280776419884 PIK3R3 other 0.589032534077043 1 1 0.625480012693922 -3.72923540925472 0.313880136893004 -412.451859576144 344.08206653936 -1.19870199491772 0.231167678485794 -919.804251938876 698.128012070777 -1.31752950180378 0.188217856050324 TSPAN1 other 1 1 1 -1.19870199491772 -1.31752950180378 8.05966324461722e-15 117.343000337358 14.5694947016071 8.05401990533098 5.0875516801504e-15 -154.945508473289 109.157833151283 -1.4194630289019 0.156336815036445 BLZF1 other 8.26760255632834e-11 1 6.50646984374434e-11 8.05401990533098 -1.4194630289019 0.00513475724269477 108.313790490384 55.3194985148911 1.95796768586446 0.050744541588667 -1019.2481784764 414.46575276458 -2.45918552178988 0.0142354702267434 SLC19A2 other 1 1 1 1.95796768586446 -2.45918552178988 0.000103514906132654 -116.615733838776 50.9972562230384 -2.28670604019858 0.0225955911141846 -445.557227418846 104.82631624472 -4.25043293879258 2.50999419272892e-05 FAAH other 0.561257821051248 0.295300816774557 1 -2.28670604019858 -4.25043293879258 2.87343075730411e-20 91.7758565782386 18.9535646617379 4.84214226801932 1.67569406301265e-06 -241.697840460805 38.8088490899406 -6.22790539087267 9.4529104387793e-10 NSUN4 essential 3.42024463041908e-16 1.32501445620369e-05 0.0159056880461161 4.84214226801932 -6.22790539087267 1.63336860742978e-07 221.600839972944 61.7930672104862 3.58617641066599 0.000366189487341156 -302.168817616265 117.282969278481 -2.5764083180635 0.0102492372148289 TMED5 other 0.00116426514337595 1 1 3.58617641066599 -2.5764083180635 4.9736088321328e-47 414.495734813173 27.6297737537459 15.001778100227 9.13695286584194e-43 -140.517249065665 83.3578629534155 -1.68571079064483 0.0924302730775352 DR1 essential 7.46439213526491e-43 1 1.38772040126407e-38 15.001778100227 -1.68571079064483 3.29340321679393e-08 716.076084283527 229.41170925564 3.12135804491821 0.00189614330647363 -1539.6360385432 461.286853659591 -3.33769763072283 0.000902736368525117 CNN3 other 0.000246774703034369 1 1 3.12135804491821 -3.33769763072283 3.47889411364555e-11 782.992434767997 110.467619700676 7.08798140929982 4.28416054532256e-12 65.8807725813688 802.137152181688 0.082131556183607 0.934572589500977 PRRC2C other 3.07116772352629e-07 1 5.13413799751455e-08 7.08798140929982 0.082131556183607 0.00199019447547666 -102.490089200524 57.4456060296666 -1.78412408335626 0.0749628202170118 -403.569246052936 114.418849139771 -3.5271220527655 0.000455723090624134 F3 other 1 1 1 -1.78412408335626 -3.5271220527655 4.46124574783227e-06 23.6856184664158 132.386826816557 0.178912200223939 0.858073748153672 -1191.97029202079 264.060329039502 -4.51400744805736 7.81428361471276e-06 ABCD3 other 0.0279898558218997 0.0949826173368336 1 0.178912200223939 -4.51400744805736 4.14231448956811e-13 73.5713674779136 9.71516954274283 7.57283412854807 1.58853576309454e-13 -83.1945218248061 70.8994535943146 -1.17341555692155 0.24114554625266 VAMP4 other 3.96999420680208e-09 1 1.96946663908462e-09 7.57283412854807 -1.17341555692155 1.73897529763194e-22 77.0717192523321 14.575142002884 5.28788805193678 1.80615340945489e-07 -171.607896009356 27.8906840903976 -6.15287511246232 1.49223825179375e-09 DPH5 other 2.16172019248627e-18 2.08226925655299e-05 0.00181699032991162 5.28788805193678 -6.15287511246232 0.0526679650723726 -1.72999502790427 1.06604020352057 -1.62282343779438 0.105214030721618 13.5624448945832 7.91282902345949 1.71398179518021 0.0871091270635216 FASLG other 1 1 1 -1.62282343779438 1.71398179518021 3.4779567643708e-07 58.9089798857256 19.3668398307811 3.04174456960693 0.00246595976375079 -111.713678155521 37.3103997112209 -2.99416996387536 0.00287754700860355 PTBP2 other 0.00241717995123771 1 1 3.04174456960693 -2.99416996387536 0.594299131817463 4.61394224960446 5.9191883898187 0.779489001826784 0.436034466413304 30.8327309673848 43.8019940846583 0.703911582376658 0.48179238296242 TNFSF4 other 1 1 1 0.779489001826784 0.703911582376658 3.44791917770252e-18 763.796687212534 83.1281547487684 9.18818286681446 8.68734068786086e-19 -662.175292563441 625.375324954398 -1.05884461081308 0.290146595166525 PRDX6 other 3.90925076367912e-14 1 1.17921962497023e-14 9.18818286681446 -1.05884461081308 9.12108859977513e-16 189.899754456126 22.089382237971 8.59687936993068 8.95075341013851e-17 75.8184451181494 166.686785120929 0.454855764739503 0.649396490775168 DARS2 other 9.65832071830188e-12 1 1.18114142000188e-12 8.59687936993068 0.454855764739503 0.532556129440302 4.87489966270852 5.70071392092581 0.855138449381587 0.39285728985011 -25.9756789235432 38.6008449641208 -0.672930319211597 0.501282179152897 HSD11B1 other 1 1 1 0.855138449381587 -0.672930319211597 9.53209799739916e-11 749.924361866898 108.422232580929 6.9167028202185 1.32635001531857e-11 -118.192590631482 734.059312304855 -0.161012316920783 0.872144594516143 IRF6 other 8.22620057175547e-07 1 1.56827625811268e-07 6.9167028202185 -0.161012316920783 2.16890952551012e-21 180.720046673045 17.786008929452 10.1607981526305 2.71251171324341e-22 192.891849188373 120.4179730726 1.60185264928914 0.109779543969895 DIEXF essential 2.63934600159326e-17 1 3.80511143133785e-18 10.1607981526305 1.60185264928914 0.75910342367468 -7.41452579685792 11.7531473989891 -0.630854489027822 0.528402575083756 -13.8733385488871 22.6593376604166 -0.612257019900557 0.540625436218844 PLPPR4 other 1 1 1 -0.630854489027822 -0.612257019900557 7.07620711971528e-11 111.794090493816 47.3749642482164 2.35977150099961 0.0186371003597089 -359.815084606041 79.7727324292969 -4.51050219352769 7.9222951808746e-06 RCAN3 other 6.15205446988047e-07 0.0962558864476264 1 2.35977150099961 -4.51050219352769 1.37086694171702e-28 42.9716632030698 29.7671788564676 1.44359206528345 0.149428312538567 -445.702295981633 47.2753485659432 -9.42779502429123 1.19097892331009e-19 SYF2 essential 1.8505332846238e-24 1.83220197562024e-15 1 1.44359206528345 -9.42779502429123 1.3287945432167e-07 8.57335204132446 46.512010902418 0.184325551077792 0.853827269704681 -352.878605386745 74.2941249986843 -4.74975114644656 2.61354257683007e-06 RSRP1 other 0.000953144325849335 0.0325725811350332 1 0.184325551077792 -4.74975114644656 1.45778956012768e-07 376.493100233911 79.243997801708 4.75106141383741 2.6020535636423e-06 -146.456479886605 151.41235232035 -0.967269034805966 0.333845790842335 SLC35A3 other 0.00104290265131534 1 0.024420272694783 4.75106141383741 -0.967269034805966 8.77410802347925e-11 217.52185546093 33.1320571995345 6.56529880263476 1.23216093942856e-10 -359.236757483659 213.540336588293 -1.68228992809106 0.0930972274783534 RCOR3 other 7.58609379710016e-07 1 1.41587613549735e-06 6.56529880263476 -1.68228992809106 4.40169388160491e-36 139.09788672631 25.872710223804 5.37623950189546 1.13054469141483e-07 -386.68333280712 45.5038534749132 -8.49781509208454 1.86137798675955e-16 MTFR1L other 6.32611444664257e-32 2.82277971692086e-12 0.00115044227798373 5.37623950189546 -8.49781509208454 9.77392801169006e-07 -30.6631521096569 32.7203543246586 -0.937127752511794 0.349109458924191 -290.324353000505 57.5685145325969 -5.04311002911348 6.25333629978574e-07 MAN1C1 other 0.00652996130461013 0.00801302513454545 1 -0.937127752511794 -5.04311002911348 2.97854369732033e-11 115.311944012405 16.6825120694266 6.91214509736408 1.36606622397102e-11 258.258625566139 107.186427112419 2.40943403492004 0.0163146209927054 NEK2 other 2.63898971582582e-07 1 1.61428045686655e-07 6.91214509736408 2.40943403492004 7.80180665160946e-21 273.341376120385 53.4703555261348 5.11201718093651 4.42134531377733e-07 -423.492319710547 87.9049453750008 -4.81761655051303 1.8866353603014e-06 RPS6KA1 other 9.39883647319392e-17 0.0236565207828192 0.00435325659594516 5.11201718093651 -4.81761655051303 5.37141016485973e-22 163.390006376514 31.2892424208993 5.22192273557188 2.52333174284808e-07 -258.11105721824 51.4192669251806 -5.01973428741823 7.01835660248325e-07 DHDDS essential 6.61865160514016e-18 0.00897577625891583 0.00251979907840809 5.22192273557188 -5.01973428741823 2.77341670892415e-08 279.15762064481 50.0609424641428 5.57635567577982 3.89562024656825e-08 -466.013980757169 309.69192575223 -1.50476632422766 0.132972083504459 NENF other 0.000209060151518702 1 0.000406624841336794 5.57635567577982 -1.50476632422766 6.1072526012504e-31 116.277261620503 9.47779098631601 12.2683926864798 1.14308833019662e-30 -71.3127389324199 58.1263832921978 -1.22685663365524 0.220415103119529 NSL1 essential 8.43228366654643e-27 1 1.6847978898768e-26 12.2683926864798 -1.22685663365524 0.859887341188888 -0.0702836166191792 6.05685033481908 -0.0116039876724606 0.990745915305409 20.0996963537727 37.0576045208637 0.5423906000847 0.58777657838903 PROX1 other 1 1 1 -0.0116039876724606 0.5423906000847 1.8168049008522e-14 195.822221856758 124.748285958463 1.56973877718817 0.117057334251552 -1252.18766329522 205.085437620548 -6.10568784319069 1.94837590736475e-09 ARID1A other 1.83787983770209e-10 2.71213926305173e-05 1 1.56973877718817 -6.10568784319069 5.62585955162225e-05 449.628359890045 103.622179691688 4.33911312450525 1.71526953536847e-05 1075.02590626255 621.216955878596 1.73051603966947 0.0841234974243401 CENPF other 0.315948272419106 1 0.151492605363743 4.33911312450525 1.73051603966947 9.55861453762305e-19 154.544451895533 33.9731513832738 4.54901725636264 6.6535251690052e-06 -264.586373323637 54.3898948698367 -4.86462373124333 1.5045498868585e-06 RPA2 essential 1.09866715495439e-14 0.0189498058249828 0.0607599918433555 4.54901725636264 -4.86462373124333 9.68708002457074e-22 167.704420889737 27.881456585926 6.01490888300259 3.30928955760458e-09 -184.713194315877 44.6449406762619 -4.1373824562856 4.07060052687629e-05 PPP1R8 essential 1.18753914021213e-17 0.472026837096574 3.60745654674475e-05 6.01490888300259 -4.1373824562856 4.81913993083811e-20 112.659739565477 39.2309627398443 2.87170468674366 0.00424209192762385 -408.988381555123 61.7735595824257 -6.62076759571224 8.5994040108069e-11 STX12 other 5.7126084740155e-16 1.23057471394647e-06 1 2.87170468674366 -6.62076759571224 1.30273801097962e-08 44.3976991628239 10.0373179494511 4.42326320501303 1.17830975041187e-05 -240.404323691287 63.5580164088228 -3.78243905764679 0.000172816220461841 MARC2 other 9.99981697227956e-05 1 0.105576553636904 4.42326320501303 -3.78243905764679 0.0225928406492234 1.06477890549516 1.99357816879978 0.534104416952061 0.593489913211299 -9.74769041619504 4.13028982762567 -2.36004997784831 0.0186284934445515 SLC5A9 other 1 1 1 0.534104416952061 -2.36004997784831 3.10224693442216e-06 122.540513446426 86.1108746762956 1.42305503116853 0.155298726364043 -713.00941631408 174.395141125194 -4.0884706518413 5.00448379376666e-05 OSBPL9 other 0.0197923354416134 0.577367295286859 1 1.42305503116853 -4.0884706518413 2.99059950125126e-26 381.232178791056 45.0725019732541 8.45819872651574 2.56255240075888e-16 -399.938530722369 90.7458575114778 -4.40723732950327 1.26386861794244e-05 TXNDC12 other 3.93054492449454e-22 0.151689511525452 3.35361232687315e-12 8.45819872651574 -4.40723732950327 1.49572187961331e-07 394.459120255692 101.852481630805 3.87284741559392 0.00012099403084335 -813.151004983668 303.031333201051 -2.68338919409423 0.00751536101444227 ESYT2 other 0.00106929157173555 1 0.99130409469957 3.87284741559392 -2.68338919409423 7.79596986980917e-14 88.109541821442 15.4678084642346 5.69631709787284 2.00119144310622e-08 -156.868373187607 46.2933601869717 -3.38857176394282 0.00075318192047569 CD3EAP other 7.70241823137146e-10 1 0.000211605983194052 5.69631709787284 -3.38857176394282 3.54186122449989e-44 786.070638576515 50.8138114111525 15.4696256145035 5.60602302787383e-45 631.567112572733 111.278243552129 5.67556687104675 2.25397808242879e-08 RCN2 other 5.27312299103544e-40 0.000304557518497778 8.5357306622407e-41 15.4696256145035 5.67556687104675 0.196335802431318 16.3129756143378 578.612840521864 0.0281932485280223 0.977518594625156 -1907.61002723459 1214.85033969642 -1.57024282325285 0.116953172384154 MUC5B other 1 1 1 0.0281932485280223 -1.57024282325285 0.000327251540452651 -3492.81400958795 2485.98972729066 -1.40499937358734 0.160591182090771 -19811.3696069375 4958.73098623518 -3.99524992622738 7.3507705148423e-05 CTSD other 1 0.837105746230241 1 -1.40499937358734 -3.99524992622738 0.468248779486595 10.3420684984548 9.2088407399806 1.1230586770335 0.261907959573289 -7.05870803986188 28.1741731886547 -0.250538249786308 0.802265721652981 COLEC11 other 1 1 1 1.1230586770335 -0.250538249786308 3.1836245420543e-07 144.074597885646 32.5660440889919 4.42407427478571 1.17080099067717e-05 -298.992552336197 116.950703546519 -2.55656907798991 0.0108419069378903 STAG1 other 0.00221643940617821 1 0.104915476774581 4.42407427478571 -2.55656907798991 7.41442263108114e-18 60.5008809539062 53.0060231238492 1.1413963430636 0.254222418208925 -709.725669517791 95.1356561119512 -7.46014374129736 3.57812725738947e-13 STK11 ts 8.34270834449249e-14 5.28203145735833e-09 1 1.1413963430636 -7.46014374129736 2.66244846505811e-17 219.454075800323 76.0483211002554 2.88571887748861 0.00405990537710256 -759.850972063597 140.882973551086 -5.39349044750298 1.03142695764048e-07 KMT2A og 2.95132412351692e-13 0.00136478415034988 1 2.88571887748861 -5.39349044750298 0.00269920913815473 -26.7382631564965 27.4242183601391 -0.974987246869372 0.330002331073713 -166.268795300927 50.6547522411616 -3.28239282484969 0.00109573136214049 TREH other 1 1 1 -0.974987246869372 -3.28239282484969 8.03049798513265e-29 23.0379366979946 31.5179663673022 0.730946166688435 0.46512673589245 -554.098217360829 58.2555003169657 -9.51151761371895 6.01885713028303e-20 IFT46 other 1.0869279022877e-24 9.26843809492284e-16 1 0.730946166688435 -9.51151761371895 0.55354702145355 -34.1570779647735 51.7932877763419 -0.659488505774599 0.509860693459807 32.2643550592881 95.3658309938581 0.338321962101562 0.735250866208099 APOA1 other 1 1 1 -0.659488505774599 0.338321962101562 0.000435294892324749 12.2098087262197 4.56075872498522 2.67714419079673 0.00764901531500418 -24.4687645240612 12.9654097772601 -1.88723418267711 0.0596599825449844 ZNF541 other 1 1 1 2.67714419079673 -1.88723418267711 0.949354826001481 1.08790224130487 8.94242338993024 0.121656311031965 0.903215892882451 -6.33222498413084 26.0153984026609 -0.24340296028229 0.807784503587381 SLC8A2 other 1 1 1 0.121656311031965 -0.24340296028229 2.12114076372466e-07 34.6057186467677 9.60540205364274 3.60273504987164 0.000343648487632974 -79.3658257241633 27.3085049314625 -2.90626769657847 0.00380613396144756 KPTN other 0.00149794960734235 1 1 3.60273504987164 -2.90626769657847 6.44611962192984e-26 433.507061901523 213.93388343345 2.02635999003112 0.0432171043158752 -3189.28379624911 395.706960747497 -8.05971113124848 4.91143573618033e-15 RPS25 essential 8.44312748080371e-22 7.37452075787476e-11 1 2.02635999003112 -8.05971113124848 2.50215337390712e-05 55.0109317285237 12.3710463450442 4.44674849597996 1.05846572643785e-05 144.550060401028 91.5284696106953 1.57929069518865 0.114853872875899 KIF14 other 0.14627588623861 1 0.0951772381212911 4.44674849597996 1.57929069518865 0.943166761735608 2.39384022244461 9.12984873781027 0.262199330042653 0.793266843264264 -13.9277017939502 65.5548792771427 -0.212458659790506 0.831828664017811 TNNT2 other 1 1 1 0.262199330042653 -0.212458659790506 3.17973458661893e-18 77.8926757024548 8.37501499824251 9.30060133848125 3.4148300337506e-19 50.5565336003593 60.4818799188821 0.835895538765749 0.403582017333408 DDX59 essential 3.60836280889516e-14 1 4.65397609634567e-15 9.30060133848125 0.835895538765749 1.84186214854878e-11 205.827900162721 29.0205536015038 7.09248703484607 4.125380767081e-12 301.984261501213 206.890144810942 1.45963579742848 0.144968462462942 CAMSAP2 other 1.64736150566203e-07 1 4.94633153973012e-08 7.09248703484607 1.45963579742848 7.42271093858175e-29 411.54715585413 34.0686080385632 12.0799521773325 6.52319753786518e-30 -469.307822302754 365.256102348685 -1.28487332390887 0.199386393252661 ATF6 other 1.00499491540705e-24 1 9.58388182263152e-26 12.0799521773325 -1.28487332390887 1.50441300887814e-14 -17.8141151065691 49.4827136155255 -0.360006834810688 0.718981487866298 -903.684068087104 113.390610009049 -7.96965522996114 9.36949063272611e-15 MREG other 1.52652788010865e-10 1.40383078150135e-10 1 -0.360006834810688 -7.96965522996114 1.68777280500181e-12 121.095435851731 20.3193378340349 5.95961526112805 4.53760237835943e-09 -138.225673535349 48.388596437822 -2.85657538575159 0.0044455113631628 FASTKD2 other 1.5816118955672e-08 1 4.9196684986173e-05 5.95961526112805 -2.85657538575159 0.492120579466997 66.5884777927481 82.1645495681626 0.810428319058784 0.41804713313376 209.16964337122 197.287978964202 1.0602249790859 0.289511029240275 NRP2 other 1 1 1 0.810428319058784 1.0602249790859 1.08121435058694e-05 66.0426795915565 30.85754491948 2.14024413685175 0.0327790991798566 -271.886446976743 75.6791156118826 -3.59262188489493 0.000357057458129386 CREB1 other 0.0655648382195923 1 1 2.14024413685175 -3.59262188489493 0.00143028202185047 34.6904214361116 29.9864274751683 1.15687076977872 0.247831972773155 -221.43142762518 73.5644314330565 -3.0100338344446 0.00273311158968508 KLF7 other 1 1 1 1.15687076977872 -3.0100338344446 1.80186791417398e-10 31.5886929314846 4.82650357109717 6.54483985480689 1.38014511369974e-10 3.15386211976023 12.6614712013822 0.249091284069417 0.803384361181986 B4GALT6 other 1.53717351758182e-06 1 1.58344048894771e-06 6.54483985480689 0.249091284069417 3.29004013410128e-10 28.6952251751531 4.43806581464085 6.46570519087158 2.34424257755624e-10 80.9459326042791 54.000922755132 1.49897313739118 0.134493314195571 C1orf54 other 2.76560773672553e-06 1 2.66915459880554e-06 6.46570519087158 1.49897313739118 0.814606847579529 1.35189380652479 3.05124801921653 0.44306257571022 0.657906884865051 -17.6388724622573 35.752293386867 -0.493363384311917 0.621966572480564 CA14 other 1 1 1 0.44306257571022 -0.493363384311917 3.85630802694145e-06 -0.433412103074296 3.03410209406132 -0.142846908125675 0.886465276488342 -62.1548953041983 12.5107636375346 -4.96811362639145 9.13146802134679e-07 CASC1 other 0.024368010422243 0.0116216193507681 1 -0.142846908125675 -4.96811362639145 0.389971051964921 -4.18602268608434 3.07340422274842 -1.36201501094475 0.173769565919549 -5.86425080114702 12.5968929782853 -0.465531525214661 0.641741379694104 LRMP other 1 1 1 -1.36201501094475 -0.465531525214661 0.000171047918743148 2.6595385991744 2.67504159089964 0.994204579181876 0.32056447997467 26.348168045831 6.31277657548715 4.1737843452503 3.48666903619811e-05 ATP10B other 0.900567292182676 0.405987742574908 1 0.994204579181876 4.1737843452503 1.260699720612e-104 535.094972915494 20.3145954465266 26.3404198387316 7.68077817662766e-98 -124.94520098191 85.4182028070998 -1.46274677850662 0.144139648778506 SPCS2 essential 1.97022152337243e-100 1 1.19989116675277e-93 26.3404198387316 -1.46274677850662 2.89562617906733e-35 106.915669261104 8.17191487066722 13.0833067834411 6.87677563037129e-34 -15.6241848973351 40.3181426995253 -0.387522436580868 0.69853275217361 USP35 other 4.14103499868419e-31 1 1.02436449790011e-29 13.0833067834411 -0.387522436580868 2.18815887637977e-06 31.7753659318758 8.18707083323694 3.88116416470684 0.000116938443773471 -14.3931764949277 17.5895768376939 -0.818278724254673 0.413562355266864 ELOVL4 other 0.014168328724559 1 0.959596869605103 3.88116416470684 -0.818278724254673 0.158096017688802 27.9407465249931 21.2986841404025 1.31185318026248 0.190132303714845 -25.6232753875457 47.4032079834458 -0.540538847001533 0.589050435337839 FILIP1 other 1 1 1 1.31185318026248 -0.540538847001533 5.688362071765e-28 183.2876865505 23.1569405302654 7.9150216891108 1.40722408434045e-14 -177.743241355383 53.2543705148494 -3.33762730902661 0.000903069547632434 CASP8AP2 other 7.62923121065122e-24 1 1.7860488078449e-10 7.9150216891108 -3.33762730902661 4.96899791991872e-22 208.940137917676 39.8175012841439 5.24744474613429 2.22976580311827e-07 -406.178108989901 85.258508576398 -4.76407710822123 2.44942645272134e-06 HMGN3 other 6.12727133505178e-18 0.030571291556415 0.00223333342840326 5.24744474613429 -4.76407710822123 1.2375647964466e-19 12.8679729271085 2.57839248792473 4.99069594228672 8.16838229766106e-07 -25.0046662418738 5.65817508586514 -4.4192104101442 1.20151825482447e-05 UBE3D other 1.45525244414155e-15 0.144350403134611 0.00790617722590614 4.99069594228672 -4.4192104101442 0.803363692972103 -0.688295760512087 11.3416516148978 -0.0606874363525659 0.951630508078668 -14.8548175109271 25.4145427408845 -0.584500679881603 0.55912671774628 CNR1 other 1 1 1 -0.0606874363525659 -0.584500679881603 3.48548322164666e-14 101.742761493687 17.8697200757765 5.69358451404089 2.04778179695448e-08 -118.037633650238 34.8851158257355 -3.38361019753757 0.000767512191878167 ANKRD13C other 3.4900143498348e-10 1 0.00021638910248418 5.69358451404089 -3.38361019753757 0.314947621614093 -20.1636945631191 13.2944474627304 -1.51670045856708 0.129926409079112 -16.9669750427767 26.9573473926214 -0.629400763942404 0.529352409357021 SGIP1 other 1 1 1 -1.51670045856708 -0.629400763942404 2.42155564318849e-09 95.8994159110604 67.0684504481284 1.42987373750688 0.153394468210381 -927.014935550828 178.120078133325 -5.20443818162346 2.87363980813327e-07 PHF3 other 1.94354055922309e-05 0.00372998447095699 1 1.42987373750688 -5.20443818162346 0.75679316751149 19.7216416075302 26.7095045484758 0.738375418822795 0.460609515680691 14.8916026067465 58.2836691175628 0.255502147208835 0.798433300260331 PLAGL1 other 1 1 1 0.738375418822795 0.255502147208835 1.24923750602488e-12 78.0193892384872 19.6498543108024 3.97048181652911 8.14365910274145e-05 -167.119235070202 43.1825031401513 -3.87006826648764 0.00012210844870213 FBXO30 other 1.17653188317423e-08 1 0.678529676440418 3.97048181652911 -3.87006826648764 0.347433131634508 -22.7064890090228 47.5046571980281 -0.477984482960659 0.632859452564536 -156.657942412384 108.716036106241 -1.44098283954441 0.150183409198123 TNFAIP3 ts 1 1 1 -0.477984482960659 -1.44098283954441 1.7120072627035e-09 21.2477790753473 5.26875792694018 4.03278711415139 6.31214444090895e-05 -32.9196562634955 12.322646825478 -2.67147608218648 0.00778148811814033 AKAP7 other 1.38552747770594e-05 1 0.531608804813351 4.03278711415139 -2.67147608218648 0.00332972950591521 35.8072642298447 17.6898670934043 2.02416807547387 0.0434446606454228 -56.3105448979293 38.6490449064752 -1.45697118865918 0.145705562233552 RAB32 other 1 1 1 2.02416807547387 -1.45697118865918 0.000710583164692715 -184.44373382052 113.930954588511 -1.61890799990822 0.106059702599029 -991.889134061609 259.162778620291 -3.82728237188283 0.000144964222783925 MYB other 1 1 1 -1.61890799990822 -3.82728237188283 2.9258999779687e-07 6.54799361617023 1.53842254294471 4.25630373540721 2.45590614222637e-05 -4.07042515026526 3.53484977877368 -1.15151290861288 0.250037557271553 ALDH8A1 other 0.00204257077461995 1 0.214474283400629 4.25630373540721 -1.15151290861288 0.261077447573147 2.57531553054619 85.9469401846501 0.0299640164619395 0.976107009409401 -283.590648909288 197.623745425007 -1.43500290564477 0.15187498707025 SGK1 other 1 1 1 0.0299640164619395 -1.43500290564477 2.43247334425141e-30 94.7452099633703 13.868865119856 6.83150417460793 2.28032421801741e-11 -198.592382479523 32.3304668034453 -6.14257702144777 1.57984508424063e-09 RNF146 other 3.33856966498506e-26 2.20325195448199e-05 2.67710063195244e-07 6.83150417460793 -6.14257702144777 0.0218889252542145 -646.478977188397 483.113623452987 -1.33815099762201 0.181413555279798 -3177.7920088121 1145.60089213529 -2.77390846203778 0.00573143352940336 CTGF other 1 1 1 -1.33815099762201 -2.77390846203778 2.46903513146397e-25 32.7301281745989 6.87322828140914 4.76197309830783 2.46166090904896e-06 -82.3650247144897 15.3076458495056 -5.38064608524699 1.10458129360383e-07 PMFBP1 other 3.20406689010079e-21 0.00145970417949746 0.0231494591886964 4.76197309830783 -5.38064608524699 1.68687537864153e-30 145.921876881921 91.5829138798559 1.59333079392243 0.111670050949682 -1758.11349265939 174.939933306803 -10.0498122951498 6.67473726698669e-22 FBXL5 other 2.31844152040491e-26 1.03358306579289e-17 1 1.59333079392243 -10.0498122951498 2.31759388088168e-22 98.9531012358461 44.2965492647356 2.23387832412089 0.0258966944700074 -664.970774967479 84.7610808637477 -7.84523708512414 2.30239685609892e-14 MED28 essential 2.87451169045755e-18 3.43701802678446e-10 1 2.23387832412089 -7.84523708512414 0.118469373032789 48.7650199405188 26.5702817669133 1.83532189715969 0.0670160697515409 104.504562024519 77.5908250263305 1.34686751931115 0.178596361373293 SLC16A7 other 1 1 1 1.83532189715969 1.34686751931115 3.77082889137682e-15 66.6543381990328 10.3822193472702 6.42004719506894 3.03799607669263e-10 -121.833496893185 31.7107820186076 -3.84202120344095 0.000136865191958566 TMEM5 other 3.91223497480345e-11 1 3.44934074547682e-06 6.42004719506894 -3.84202120344095 9.31238624120957e-08 25.7717448783213 6.66955793173079 3.86408591725559 0.000124901863098757 -67.9360392389174 23.4211886303848 -2.90062303459623 0.00387428834318041 ZNF430 other 0.000674123640001161 1 1 3.86408591725559 -2.90062303459623 0.00408465407764144 251.313303539607 96.6540345286989 2.6001325735139 0.00957295995245564 -607.372593397895 352.520969563111 -1.72294032366536 0.0854696963881981 VAMP8 other 1 1 1 2.6001325735139 -1.72294032366536 4.88162608381015e-188 244.80419839963 5.317517973625 46.0373053018087 2.91432469055181e-189 166.092181370261 29.013177479402 5.72471531214321 1.71877995559903e-08 DCLRE1B essential 7.65146072376403e-184 0.000233169688776565 4.56849538490901e-185 46.0373053018087 5.72471531214321 7.90980404034945e-30 1377.87384563884 196.763416053936 7.00269325097073 7.60932062582388e-12 -2621.4161329014 447.884711110636 -5.85288148461458 8.45535258440657e-09 MYL12B other 1.08087472211375e-25 0.000115880607169292 9.05509154473042e-08 7.00269325097073 -5.85288148461458 7.33018268582933e-48 877.89167608964 68.0479491937263 12.9010747052841 2.65868542331119e-33 -667.693340982152 195.325226212346 -3.41836717115216 0.000678533676872036 FOXO3 other 1.10253277777559e-43 1 3.95293348737907e-29 12.9010747052841 -3.41836717115216 4.48986066655961e-56 34.914794070039 2.15370018161968 16.2115388056389 2.79292873925577e-48 -0.951387967276768 6.17699520428447 -0.154021160096881 0.87765179094375 ARMC2 other 6.8614050706364e-52 1 4.27318097106133e-44 16.2115388056389 -0.154021160096881 1.88090357517368e-52 2967.94356643589 171.591415429462 17.296573718491 1.56736349179772e-53 1473.89313356991 1145.97016274594 1.28615314908218 0.198948035923192 RPN2 essential 2.85728062104634e-48 1 2.41060505038489e-49 17.296573718491 1.28615314908218 5.73175391357646e-18 242.363765813905 26.7468915644983 9.06138065537304 2.47886240888967e-18 -112.559609914594 176.668657091209 -0.637122689263904 0.524320035491235 TGIF2 other 6.46369888834017e-14 1 3.34522482079661e-14 9.06138065537304 -0.637122689263904 0.733920735438839 -15.1959173641386 23.5986445913599 -0.643931786222259 0.519895103597947 -36.9490586825004 55.8051732967182 -0.662108125460715 0.508186491299492 CASQ2 other 1 1 1 -0.643931786222259 -0.662108125460715 0.577068167849264 -9.91234801925054 9.46138620662927 -1.0476633976008 0.295266782161819 -8.85059218846653 18.2187636525025 -0.485795433613347 0.627311108605112 OLFM3 other 1 1 1 -1.0476633976008 -0.485795433613347 0.050844678831871 18.5691218010108 26.2477425573847 0.70745595589463 0.479583920806825 -125.734818510457 64.4838190620907 -1.94986618874711 0.0517016587628869 PKD2 other 1 1 1 0.70745595589463 -1.94986618874711 0.017738577627845 -33.050323517896 13.314721435003 -2.48223920261751 0.013354385387664 -71.2347879727161 32.7107783078782 -2.17771608190562 0.029852940769954 ABCG2 other 1 1 1 -2.48223920261751 -2.17771608190562 0.951739826957476 -40.3444454635587 641.281263452693 -0.0629122473442339 0.949859322078709 420.594657781216 1575.45986554787 0.266966278848972 0.789595557135447 SPP1 other 1 1 1 -0.0629122473442339 0.266966278848972 3.85406852502121e-06 95.7667397759583 32.2582304568232 2.96875366130636 0.00312309651900573 -253.780099740011 90.4693703315396 -2.80514939818851 0.00521092844273574 STBD1 other 0.0243577130781341 1 1 2.96875366130636 -2.80514939818851 7.90897370103749e-15 649.700879094256 244.367605006953 2.65870297773623 0.00807777109673514 -4042.48637330076 633.69925390116 -6.37918752217954 3.84065095114336e-10 CCNI other 8.11618881200467e-11 5.42991231472648e-06 1 2.65870297773623 -6.37918752217954 0.0834721570015644 399.911807168088 181.588532678562 2.20229659477446 0.0280694041730034 317.391908353135 696.04695873253 0.455992091296673 0.64858035473371 RARRES1 other 1 1 1 2.20229659477446 0.455992091296673 1.69461162303884e-07 212.355761476949 40.2673767320619 5.27364280245914 1.94336576815982e-07 -289.033733827136 154.348871578264 -1.87260023913151 0.0616677672030939 MFSD1 other 0.00120605509211675 1 0.0019528882604238 5.27364280245914 -1.87260023913151 1.92852584470773e-16 237.248053919882 28.0086626660226 8.4705241642147 2.3988313778234e-16 -273.466512300782 176.93901222597 -1.54554108141813 0.122810063255582 RAB3GAP2 other 2.08377217520671e-12 1 3.14078992298417e-12 8.4705241642147 -1.54554108141813 3.10164474065474e-38 176.205793103502 14.4725758386005 12.1751507864644 2.54505664888994e-30 -226.834108449694 70.4388122177875 -3.22030002079468 0.00135716845270861 EEF2KMT other 4.50637964369727e-34 1 3.7460688815011e-26 12.1751507864644 -3.22030002079468 8.1948363159665e-11 456.29956667321 66.2089579656767 6.89181012197412 1.53551640133275e-11 936.996407786091 329.387539217859 2.84466258198783 0.00461387102716876 PPL other 7.10000618415338e-07 1 1.81221645685291e-07 6.89181012197412 2.84466258198783 4.97017353506611e-24 395.542203008232 38.3785249936208 10.3063419731211 7.25135462344836e-23 -110.928757008513 190.931987073611 -0.580985714906668 0.561491584763595 UBN1 other 6.32752792749266e-20 1 1.02287608318362e-18 10.3063419731211 -0.580985714906668 0.151032648044822 23.0550102122659 19.5940747246735 1.17663173873856 0.239893566872611 -30.9688713277315 36.7041062353436 -0.843744052209356 0.39920957333248 KLF12 other 1 1 1 1.17663173873856 -0.843744052209356 1.93568091443772e-25 182.324986326515 17.5487428508181 10.3896323444055 4.09701825262823e-23 25.3324928262728 33.5732928159512 0.754542992406063 0.450862850948848 UCHL3 other 2.51696589304337e-21 1 5.78990619461421e-19 10.3896323444055 0.754542992406063 0.543181546330359 16.6218985229491 16.1700654904997 1.02794256045004 0.304466039598581 24.3836666819166 27.5848818469827 0.883950376049328 0.377141150259034 PCDH17 other 1 1 1 1.02794256045004 0.883950376049328 1.82268753991424e-12 109.839296778541 19.3386922034843 5.67976860186807 2.20042809879316e-08 -194.696717058652 56.4298899504735 -3.45024094907027 0.000603635322068509 HS1BP3 other 1.70530646234376e-08 1 0.000232255185827618 5.67976860186807 -3.45024094907027 0.000148222400198011 20.435551159548 10.9092472269092 1.87323201450059 0.0615743144093044 -101.760248384175 31.5582871821152 -3.22451747133618 0.00133785139500097 LDAH other 0.787209167451634 1 1 1.87323201450059 -3.22451747133618 1.22658380998063e-05 28.4317682333923 24.2342633208741 1.17320538515824 0.241226879656437 -294.95369959551 69.6905822497942 -4.23233226174374 2.71458821371498e-05 WDR35 other 0.0739752695799317 0.318611218643728 1 1.17320538515824 -4.23233226174374 0.396415951266663 -26.0216154760975 24.9687088001538 -1.04216904784188 0.297797937800165 -100.094603090678 89.0768440598675 -1.12368825082539 0.261642752365192 CCND2 og 1 1 1 -1.04216904784188 -1.12368825082539 6.06850599578159e-10 182.485382611821 68.057657656548 2.68133504583322 0.00755512373949865 -719.099451246496 158.453155457702 -4.53824633008621 6.98413999386326e-06 ELL2 other 5.03018461990336e-06 0.0851506348051809 1 2.68133504583322 -4.53824633008621 1.17471037684949e-07 -20.3310144753221 6.14325812095118 -3.3094840026312 0.000997031827663597 -82.8807031386245 15.4224287506261 -5.37403702612404 1.14698742744434e-07 DNAH7 other 0.00084543905821858 0.001514711596683 1 -3.3094840026312 -5.37403702612404 3.32497164216502e-10 15.6353589534833 7.97726970362549 1.9599887598607 0.0505119214960986 -110.950074802943 19.6126134373608 -5.65707753111526 2.50201318594923e-08 CYP20A1 other 2.79364117374705e-06 0.000337696719707568 1 1.9599887598607 -5.65707753111526 5.77804752491957e-17 136.896815944275 16.7580006854453 8.16904226905617 2.2232374398188e-15 -67.1400652006623 41.7690421848171 -1.60741213321543 0.108549584914762 NDUFB3 other 6.33909593958926e-13 1 2.86152890879078e-11 8.16904226905617 -1.60741213321543 2.4793943344325e-09 134.435712123545 23.5861638596629 5.69977012469827 1.97540748151567e-08 -86.6237548464886 59.6747122233194 -1.45159903783563 0.147193831333595 GTF3C3 other 1.98797837734798e-05 1 0.000208998111544357 5.69977012469827 -1.45159903783563 0.0950318113476779 32.748040248794 18.6149847800823 1.75923003084235 0.0791057760340702 -36.4363437205395 46.4294374093415 -0.784768150415035 0.432934293122545 SATB2 other 1 1 1 1.75923003084235 -0.784768150415035 8.01087255389595e-33 222.937740455874 31.0746354783725 7.17426727695763 2.38590706555722e-12 -523.857608993094 71.3707026450665 -7.33995308408675 7.81231946746496e-13 UBE2B other 1.12504694146915e-28 1.14872345449605e-08 2.87692673964889e-08 7.17426727695763 -7.33995308408675 0.00898152754698179 13.3638548555866 4.35442840451248 3.06902619910749 0.00225463892582074 12.0648373691583 9.48553999728543 1.27191887574255 0.203945401222921 TRPM6 other 1 1 1 3.06902619910749 1.27191887574255 0.00052988198193183 0.191348524042734 67.1257208367615 0.00285059916910332 0.997726599020916 -556.57642424461 150.00832836855 -3.71030348979808 0.00022829327212071 KLF9 other 1 1 1 0.00285059916910332 -3.71030348979808 1.95493590934036e-13 286.106246675096 46.960035153241 6.09254754050902 2.11132096940226e-09 -297.153207736116 106.201586042834 -2.79801101667413 0.00532509485836147 TJP2 other 1.9023481333791e-09 1 2.31823042440369e-05 6.09254754050902 -2.79801101667413 0.619429938216681 26.2386799759803 27.9891023878636 0.937460573489408 0.348935416712329 39.5514717435523 87.2617150610145 0.453251139012079 0.650547653463362 C2orf40 other 1 1 1 0.937460573489408 0.453251139012079 1.26036556949017e-16 424.575399659253 51.3974069263377 8.26063852341327 1.12426322443578e-15 -201.639305559522 156.515312911613 -1.2883040119748 0.198191883777189 ITGB1BP1 other 1.36900908158022e-12 1 1.45378477551791e-11 8.26063852341327 -1.2883040119748 7.43098343279012e-35 322.677011562147 24.6731725624683 13.078051099638 3.78557640345466e-34 -30.5106478161867 75.1347111668796 -0.406079258738619 0.684845230582963 CPSF3 essential 1.05898944900692e-30 1 5.6435373022702e-30 13.078051099638 -0.406079258738619 5.10234977400116e-05 19.6909835583112 4.57413291198355 4.30485601035417 1.98766102768131e-05 -24.0236738123592 20.2333995726288 -1.18732760286402 0.235625323150982 PIGZ other 0.287976621244626 1 0.174715404333187 4.30485601035417 -1.18732760286402 2.01323373681885e-38 220.185043990004 15.3987119599514 14.2989260765871 1.63943010260639e-39 -35.4022736084378 68.1152686169771 -0.519740644458299 0.603459322850344 SENP5 other 2.92784582345565e-34 1 2.47586734095617e-35 14.2989260765871 -0.519740644458299 9.38088184524253e-07 22.1861963182789 22.71562238667 0.976693305629972 0.329155928285116 -244.620176272118 51.5359653747647 -4.74659152095556 2.64946929214091e-06 CCDC92 other 0.00628050039538988 0.0330044389721993 1 0.976693305629972 -4.74659152095556 8.92898680780565e-09 411.596273656797 66.6284462338369 6.17748569750933 1.27818072231893e-09 -36.8547662794982 400.09315542783 -0.0921154630603175 0.926640276339707 C1orf198 other 6.92710796549562e-05 1 1.41686333069053e-05 6.17748569750933 -0.0921154630603175 0.701466648566362 -9.1053783679031 12.6420946544185 -0.720242856647231 0.471685398106025 -36.2990059141018 77.0886125678259 -0.470873773764762 0.637919976936979 TRIM67 other 1 1 1 -0.720242856647231 -0.470873773764762 4.93037348103595e-21 480.726688898687 48.3782795483652 9.936828952714 1.71246031099702e-21 -388.115958073805 301.535954462234 -1.28712995027734 0.198596375324748 HEATR1 essential 5.96131457592057e-17 1 2.38631344337435e-17 9.936828952714 -1.28712995027734 8.01997036776666e-06 524.08323264384 136.309564735172 3.84480160040165 0.000134887959234551 -475.918718025 295.41241278832 -1.61103155257739 0.107751806794531 PTBP3 other 0.0491624183544096 1 1 3.84480160040165 -1.61103155257739 6.17867178571271e-23 948.506161292995 134.423687897763 7.05609387844192 5.22541097035184e-12 -1441.50531740687 281.56898239884 -5.11954585738065 4.25375634039137e-07 RAD23B other 7.73507920853374e-19 0.00548692030347083 6.24593373286155e-08 7.05609387844192 -5.11954585738065 2.87487148001131e-19 219.191105718276 45.2145652651941 4.84779858951796 1.63055099348446e-06 -628.348243388366 100.67300664707 -6.24147687960857 8.71817140134822e-10 FKBP15 other 3.34980024850917e-15 1.22289790246711e-05 0.0154886038871089 4.84779858951796 -6.24147687960857 0.0692258023828109 64.3635859000272 28.5990949356089 2.25054625137412 0.0248114362798566 13.8989660572416 60.3001001956443 0.230496566542116 0.81779226738159 CTNNAL1 other 1 1 1 2.25054625137412 0.230496566542116 2.07770106645147e-17 75.3222785951754 14.5679370274008 5.17041489495059 3.28315402666856e-07 -164.677005764903 30.7536663309812 -5.35471133726281 1.26439243807701e-07 FAM206A other 2.30707926418771e-13 0.00166545771943504 0.00325787374066321 5.17041489495059 -5.35471133726281 1.30497083062932e-05 422.718867142606 97.036354167761 4.3562937907971 1.58197468257908e-05 -93.2838732648296 220.354789060683 -0.423334903055546 0.672218551930671 WDR34 other 0.0785461942955786 1 0.14014713712968 4.3562937907971 -0.423334903055546 2.43565455001936e-13 1307.37249378043 181.705295142722 7.1950159336498 2.08121001452118e-12 -193.784382988334 411.93945355923 -0.470419575775039 0.638243825055002 SET other 2.36112352078877e-09 1 2.51347733453723e-08 7.1950159336498 -0.470419575775039 1.15509575785588e-23 674.431599550199 145.004147297314 4.65111937913994 4.14969169084316e-06 -2420.62421251732 320.990104613735 -7.54111786539399 1.96559715824207e-13 PTPA other 1.4626977581729e-19 2.90928035391409e-09 0.0383846481402992 4.65111937913994 -7.54111786539399 3.42090017614284e-28 278.35984632113 33.808040436304 8.23353979493648 1.36083677058077e-15 -410.681106358985 76.5279980772673 -5.36641643159588 1.19140556179823e-07 GLE1 essential 4.6007686468945e-24 0.00157217877934895 1.75724852185095e-11 8.23353979493648 -5.36641643159588 1.24114171251386e-29 511.459214632775 72.1799669245261 7.08588873651848 4.31790409778049e-12 -1393.52082006733 178.73623972776 -7.79652085212182 3.27879422488681e-14 RAB14 other 1.69266906752641e-25 4.88769855103876e-10 5.17328089955081e-08 7.08588873651848 -7.79652085212182 7.66368812705915e-07 62.0902180737744 18.417181458818 3.37132031916024 0.000801531613416684 -144.077212114804 45.7817592761297 -3.14704402785861 0.00174012344513683 CNTRL other 0.00517355893329757 1 1 3.37132031916024 -3.14704402785861 1.39237669371192e-25 64.5635436530182 14.1513084202105 4.5623727316133 6.26579151546687e-06 -264.699010372123 31.1719707729253 -8.49157123559315 1.98213868930533e-16 TRIM32 other 1.81315293055166e-21 3.00472403911795e-12 0.0573006634089446 4.5623727316133 -8.49157123559315 2.9865883216198e-20 280.295283363844 57.7708706967002 4.8518445365902 1.60441077888962e-06 -882.971095776621 132.360042296062 -6.67097925068352 6.32421721462671e-11 FBXW2 other 3.55404010272756e-16 9.0689274857747e-07 0.0152515288641247 4.8518445365902 -6.67097925068352 3.12393540382283e-08 175.810684606084 29.7972946167556 5.90022305270702 6.42515652976423e-09 187.390020483984 68.2894085258696 2.74405686810124 0.00627110736595856 PHF19 other 0.000234545070119018 1 6.93081634865667e-05 5.90022305270702 2.74405686810124 7.10042393958358e-07 164.323874215129 44.1879243240514 3.71875069329039 0.000220977486166127 -258.504715691821 100.462137765856 -2.57315563296405 0.0103414008081061 NEK6 other 0.00480627696470413 1 1 3.71875069329039 -2.57315563296405 8.62158537605227e-14 146.207982545471 58.0179175095562 2.5200487852979 0.0120179228523615 -808.603603883732 128.537454476604 -6.29080144130993 6.48090819521114e-10 BSPRY other 8.50433181493796e-10 9.11993401230111e-06 1 2.5200487852979 -6.29080144130993 7.42458375193058e-34 215.890978382385 40.9686193859908 5.26966692112179 1.97590511734285e-07 -927.710695732345 93.8060854537403 -9.88966431383428 2.58868816008621e-21 PPP6C other 1.05057860089818e-29 4.00237076430929e-17 0.00198420391883569 5.26966692112179 -9.88966431383428 3.82542266927201e-18 219.520816401191 26.9457397628436 8.14677267476232 2.60219992942752e-15 -143.759844279922 67.039103670546 -2.1444177563353 0.0324442723188617 NDUFA8 essential 4.33267371521748e-14 1 3.34434734930025e-11 8.14677267476232 -2.1444177563353 8.17952852709291e-10 56.2020419330242 25.333499374357 2.21848711472971 0.0269321739298101 -286.993875626104 56.125825647364 -5.11340140329113 4.38542636358675e-07 HDHD3 other 6.7260263078285e-06 0.00565544583848148 1 2.21848711472971 -5.11340140329113 7.60105269019029e-25 174.383546374285 27.7845615113527 6.27627491270763 7.11583154970768e-10 -493.936788630694 69.138939629202 -7.14411865845381 2.94089050649537e-12 RBM18 other 9.80383775980743e-21 4.30017009859753e-08 7.96546183674278e-06 6.27627491270763 -7.14411865845381 0.0109625739177404 1.42244509651762 1.36004585792593 1.04588024604321 0.296082529271216 -7.05082295525774 3.03147089769931 -2.32587519167967 0.0203932090467958 SLC46A2 other 1 1 1 1.04588024604321 -2.32587519167967 3.13932998121542e-17 225.32045399579 60.4614522334607 3.72667949035951 0.000214311963891484 -864.970297707714 131.867727536646 -6.55937820318729 1.2591865036688e-10 HSDL2 other 3.47147109322801e-13 1.79685914073537e-06 1 3.72667949035951 -6.55937820318729 8.09297212133952e-20 282.308760046524 38.1231629321861 7.40517675694166 5.04129669480694e-13 -323.177135398456 87.2908273058961 -3.7023034993807 0.000235514393691804 MAPKAP1 other 9.54970710318063e-16 1 6.16953889510473e-09 7.40517675694166 -3.7023034993807 0.302567829443651 26.8083662078428 23.1169961736774 1.15968208007789 0.246688878417907 -28.5494660848587 48.4300891908904 -0.589498523786092 0.555772542139051 NR4A3 other 1 1 1 1.15968208007789 -0.589498523786092 1.03533033760466e-08 39.3964770000024 8.29019772417909 4.75217579975192 2.58247245127703e-06 -37.5809157033709 17.3620915916811 -2.16453850072865 0.0308597246549075 INVS other 7.9937855366456e-05 1 0.0242442513725887 4.75217579975192 -2.16453850072865 0.0227586490490239 55.0446765785575 20.2442510377025 2.71902756372875 0.00675689331917945 19.0548622965272 42.5557688477608 0.447762143945612 0.654503446534276 GALNT12 other 1 1 1 2.71902756372875 0.447762143945612 2.76522141504291e-14 83.7605078739527 17.3153120369111 4.83736635501574 1.71801606652379e-06 -197.045819767624 41.2240917703398 -4.77987049091027 2.26351736038271e-06 DENND1A other 2.7773883892691e-10 0.028282649417982 0.0162967311190782 4.83736635501574 -4.77987049091027 2.48165527613111e-18 66.9159391163554 26.0255000209459 2.57116824124416 0.0103997179422503 -418.184891926241 54.698214253323 -7.64531159992734 9.47318733544102e-14 ALG2 essential 2.82511636634765e-14 1.40752617429983e-09 1 2.57116824124416 -7.64531159992734 0.181983774870015 123.045380632966 71.8236720374649 1.71315914575884 0.0872540677751098 -2.66950918036377 145.034455352461 -0.0184060344411013 0.985321699515342 CSF3R other 1 1 1 1.71315914575884 -0.0184060344411013 1.57894926214364e-35 431.147124429421 47.324575562533 9.11042770705294 1.57132139927051e-18 -568.711798927129 103.360193815321 -5.50223231917767 5.786223502376e-08 KDSR other 2.26152902816833e-31 0.000771882215216958 2.12584072107307e-14 9.11042770705294 -5.50223231917767 2.13498451979122e-34 460.372630245948 47.3980175826247 9.71290897226707 1.1375569769552e-20 -454.868803206831 103.520596340661 -4.39399326593877 1.33877083701848e-05 VPS4B other 3.03253201191144e-30 0.160465072525035 1.57403758901291e-16 9.71290897226707 -4.39399326593877 0.00237860837755351 64.4589602119433 18.8180394097181 3.42538129549538 0.000660456719451106 81.7915271127536 39.1538221299153 2.08897938089832 0.0371754436766193 ONECUT2 other 1 1 1 3.42538129549538 2.08897938089832 1.91400105260962e-15 27.8682229586301 26.3659896681777 1.05697617686111 0.291028817097152 -331.268567721873 47.7514766074977 -6.9373470991232 1.23163601808016e-11 C19orf25 other 2.00395910208227e-11 1.78685753503069e-07 1 1.05697617686111 -6.9373470991232 1.30143550870801e-20 89.963533681323 10.3845234478855 8.66323179227273 6.28648867735853e-17 -107.333024028253 38.0128529725495 -2.82359822099547 0.00493710790028084 ZBTB45 other 1.55924988298307e-16 1 8.31891046674854e-13 8.66323179227273 -2.82359822099547 4.79292514630763e-16 98.7210960910323 50.5137887367296 1.95433956865822 0.0511701693771947 -685.31188404134 100.482038185762 -6.82024266639973 2.41342698662673e-11 YLPM1 other 5.11453042362487e-12 3.484988568689e-07 1 1.95433956865822 -6.82024266639973 3.54576295315718e-13 130.653438798112 16.9196063876806 7.72201408262327 5.54793287592578e-14 84.391915738525 33.1410854811834 2.54644392340258 0.0111576271361068 DCAF4 other 3.41173311352784e-09 1 6.95155989353501e-10 7.72201408262327 2.54644392340258 2.77828591935924e-24 2.05980786208965 0.897159940892901 2.29592045766067 0.0220577381032022 -15.5557633168974 1.78463072547135 -8.71651658512651 3.43109687970817e-17 PROX2 other 3.55176071930885e-20 5.22556054779554e-13 1 2.29592045766067 -8.71651658512651 1.01364105559217e-20 135.382381485045 21.1566247426616 6.39905387233396 3.36256559898961e-10 -178.821825415814 42.084761971699 -4.24908724768521 2.52316344400114e-05 FCF1 essential 1.2173829077662e-16 0.296724021014535 3.81314938925421e-06 6.39905387233396 -4.24908724768521 0.123626409430745 9.32650079459575 12.576854315424 0.741560692418767 0.458671803092403 -35.2009222411816 24.8881330892572 -1.41436571859124 0.157823484918595 PGF other 1 1 1 0.741560692418767 -1.41436571859124 0.00646854118123303 11.4738753354147 19.5549125706841 0.586751553807297 0.557613092567768 -106.554368120927 40.5210064267726 -2.62960813457303 0.00878935829312387 IFI27L2 other 1 1 1 0.586751553807297 -2.62960813457303 9.12410722134102e-24 -23.6098147251737 23.8472676952437 -0.990042759904219 0.322591755050541 -484.014888456465 47.5848611196908 -10.1716150277084 2.26156672963926e-22 BBOF1 other 1.15711927781047e-19 3.50678537097863e-18 1 -0.990042759904219 -10.1716150277084 1.14056123775767e-39 93.4349346994238 51.1072012779088 1.82821466179192 0.0680618021386368 -1245.06880447004 101.237513867944 -12.2984924945325 7.31359934206092e-31 NEK9 other 1.66795675409682e-35 1.1447977050128e-26 1 1.82821466179192 -12.2984924945325 9.60686515281657e-05 21.6673358749035 5.24695166646041 4.12950933270562 4.20369119131504e-05 5.65732974416687 10.3768217764366 0.545189063284614 0.58584571409363 ACYP1 other 0.523285944873919 1 0.359583744505089 4.12950933270562 0.545189063284614 3.9188985603004e-34 114.626608134237 15.5753817761262 7.35947341656408 6.82499171512506e-13 -220.463943638441 32.1311215044163 -6.86138339765508 1.85561650662126e-11 IFT43 other 5.55543059908185e-30 2.68377815352633e-07 8.32102989908047e-09 7.35947341656408 -6.86138339765508 1.59718949336809e-18 48.1010537610289 21.3364631472594 2.25440615105917 0.0245676102827201 -302.145880092595 41.9207967230668 -7.20754145224392 1.91376627336433e-12 DNAL1 other 1.82558759091973e-14 2.80405034373342e-08 1 2.25440615105917 -7.20754145224392 1.83070817714579e-15 75.2779574411794 60.3162100119704 1.2480551650417 0.212547767934886 -896.463137898126 126.768089557759 -7.07167821985417 4.72416968627651e-12 IRF2BPL other 1.91803295719565e-11 6.8887842365284e-08 1 1.2480551650417 -7.07167821985417 1.14228164633456e-18 114.293582637644 33.8733370442359 3.37414593927919 0.000793219231576727 -429.955331382197 66.5638047166116 -6.45929620779171 2.33606892296152e-10 ACOT2 other 1.30985436385184e-14 3.31745147749765e-06 1 3.37414593927919 -6.45929620779171 1.98217292361717e-07 -661.417645889977 234.081318829482 -2.82558919779408 0.00489242657580303 -2617.77114432173 465.657595569594 -5.62166529490336 3.02293892910926e-08 LTBP2 other 0.00140238734345915 0.000406948038636689 1 -2.82558919779408 -5.62166529490336 1.21103149389681e-12 152.307706383226 27.1434181894663 5.6112205662562 3.19534971036846e-08 -121.439072297024 53.9936926374895 -2.24913441487247 0.0249009547131581 AREL1 other 1.14067056410141e-08 1 0.0003347448356582 5.6112205662562 -2.24913441487247 6.34593116089953e-27 29.9620371838361 12.7951992357883 2.34166241820073 0.0195560057064355 -235.784029830913 25.3048837694634 -9.31772822902448 2.89341077393237e-19 MLH3 other 8.41153175377233e-23 4.44283224337316e-15 1 2.34166241820073 -9.31772822902448 4.06343384631237e-16 78.2163005955594 19.755934117698 3.95912945090714 8.51558351476413e-05 -215.906210754252 40.6802235939733 -5.30739980461263 1.6186111921937e-07 TTLL5 other 4.34746787216961e-12 0.00212232299520438 0.708326236758081 3.95912945090714 -5.30739980461263 3.61287159001561e-05 27.9563078541952 7.43772392353226 3.75871814302545 0.000189188153127803 58.0684489458136 14.7821990193465 3.92826864729769 9.65315850906831e-05 FLVCR2 other 0.207993017437199 1 1 3.75871814302545 3.92826864729769 1.83824497959391e-32 54.0745997813821 16.4662254092485 3.28397057840654 0.00108899667410983 -323.996756560913 32.6718262590285 -9.91670174762206 1.99139593353394e-21 ABCD4 other 2.57280767343964e-28 3.08009209039694e-17 1 3.28397057840654 -9.91670174762206 2.42779307987822e-37 262.124804851477 37.7668122070714 6.94061239307873 1.10892578485769e-11 -609.027207095096 75.1257500427029 -8.1067704049399 3.42446606356091e-15 DLST other 3.51131713142788e-33 5.1503969595956e-11 1.31396616247788e-07 6.94061239307873 -8.1067704049399 0.157507808290826 -22.3800338779579 18.7525501419092 -1.19343949002125 0.233215592340456 -72.4811081142789 38.8583790427089 -1.86526329455522 0.0626806544209011 PPP4R4 other 1 1 1 -1.19343949002125 -1.86526329455522 3.58329396344873e-18 -343.860481492539 98.3951083140546 -3.49469081730176 0.000513082855604411 -1881.75356803786 202.609250614132 -9.28759946712229 3.69564203934527e-19 TGFB3 other 4.06166370756914e-14 5.67244096619105e-15 1 -3.49469081730176 -9.28759946712229 8.70963569380865e-14 16.4761629389506 3.41203594991461 4.82883626691064 1.78501705283369e-06 -24.9894689803573 6.74793502928216 -3.70327646486183 0.000234429186374645 ZC2HC1C other 8.58770079409533e-10 1 0.0169130365755992 4.82883626691064 -3.70327646486183 1.53654587348403e-30 303.77949072723 29.6230756063222 10.2548261620207 1.12562974917819e-22 -131.119763376526 62.1837758356591 -2.10858478139142 0.035437844727425 SLIRP other 2.11259692145319e-26 1 1.58443643494323e-18 10.2548261620207 -2.10858478139142 2.45209077031367e-11 150.65330213965 62.2858235205967 2.41874143463531 0.0159027000244214 -609.539685208849 122.040245394898 -4.99457931468838 7.96468441394096e-07 RBM25 essential 2.18137994927104e-07 0.0101613443753059 1 2.41874143463531 -4.99457931468838 8.91213049952274e-27 86.6028241538058 52.6209543400754 1.64578588966887 0.100383328040251 -1015.57187456005 104.999903395956 -9.67212198977284 1.57005212769842e-20 ALDH6A1 other 1.17960959291683e-22 2.42211941740035e-16 1 1.64578588966887 -9.67212198977284 6.93080474834814e-05 26.0224547738945 15.2294659517432 1.7086912211072 0.0880796092162183 -93.9388591045564 30.8960500562732 -3.04048119204425 0.00247593942506744 GPR68 other 0.384728971580805 1 1 1.7086912211072 -3.04048119204425 0.0689989355272214 -0.248896599718234 3.32907008447114 -0.0747646019467249 0.940429390109472 -14.8871714107665 7.0004751867711 -2.12659441160495 0.0339016353017244 ESRRB other 1 1 1 -0.0747646019467249 -2.12659441160495 2.72911147021991e-42 90.8523504301284 11.9654312106743 7.592902322574 1.3602992618545e-13 -204.679675156202 23.6638633332676 -8.64946151326252 5.7614143002975e-17 EIF2B2 essential 4.03553713101418e-38 8.7631111507525e-13 1.6884034438138e-09 7.592902322574 -8.64946151326252 2.1990338172772e-41 97.6455503046704 13.5374239820561 7.21300820851142 1.8527110315914e-12 -252.420644965927 27.5647019859079 -9.15738704866004 1.08418371268646e-18 NRDE2 essential 3.23873700608585e-37 1.66237888666215e-14 2.24029817940033e-08 7.21300820851142 -9.15738704866004 5.41609165134482e-19 31.0634638479358 33.1132858453734 0.938096690041288 0.348609498638872 -530.109909606116 65.3045654958605 -8.1175015189362 3.17502709053458e-15 COQ6 other 6.26208516728488e-15 4.77682825770928e-11 1 0.938096690041288 -8.1175015189362 5.3616686432814e-48 205.887017740458 26.0778635690487 7.89508761694806 1.60528123836614e-14 -485.977600995748 51.4536118533782 -9.4449657369163 1.03455994804207e-19 ZNF410 other 8.06770280754553e-44 1.59187739205233e-15 2.03340974463839e-10 7.89508761694806 -9.4449657369163 1.98736307011628e-05 285.259983027738 61.3678016636866 4.64836567865092 4.20331350195421e-06 -4.92672494898692 211.573251929507 -0.0232861427616967 0.981430563982386 RHOQ other 0.117612146489481 1 0.0388596333255666 4.64836567865092 -0.0232861427616967 0.0205306759766181 4.54654706549741 1.70894019727773 2.66044831336981 0.00803484735509632 -2.73746651793955 6.08839109828088 -0.449620675437966 0.653163728582393 GPR75 other 1 1 1 2.66044831336981 -0.449620675437966 8.67963481454857e-20 133.669565710316 16.2326537481763 8.23460955823898 1.35471943064566e-15 -165.138075446695 50.1243818201486 -3.29456582705055 0.00105013482272726 SUPT7L other 1.02393651907229e-15 1 1.74948467273581e-11 8.23460955823898 -3.29456582705055 0.541788910998913 -10.3114765553215 10.5055543972012 -0.981526168487456 0.326772876571237 -22.79103521458 30.3731249827027 -0.7503684664505 0.453359637048938 KLHL29 other 1 1 1 -0.981526168487456 -0.7503684664505 7.07403180368708e-23 358.670721290743 35.2085649826845 10.1870303849968 2.06912403872345e-22 -28.4475256622694 103.593941751247 -0.274606074268112 0.783723923086836 DNMT3A other 8.8460767705107e-19 1 2.90587779998322e-18 10.1870303849968 -0.274606074268112 7.52727868696786e-13 419.713272157936 64.19226625402 6.53837754375359 1.44506887060186e-10 -444.521966392793 193.279447569267 -2.29989257514556 0.0218355253360597 TMEM214 other 7.14037656245772e-09 1 1.65648244637091e-06 6.53837754375359 -2.29989257514556 5.44596519071597e-14 101.439586497028 14.1960708539327 7.14561004525605 2.91785403230852e-12 -69.6396574129032 40.8815885708086 -1.70344792967828 0.0890596368180022 ATAD2B other 5.41111101349539e-10 1 3.51076197167362e-08 7.14561004525605 -1.70344792967828 0.0770395599149324 1.608581610087 3.76622139014387 0.427107555147085 0.669470917551479 -22.1394937831504 10.8477976174375 -2.04092061485015 0.0417435306097574 FKBP1B other 1 1 1 0.427107555147085 -2.04092061485015 5.13078570566736e-11 487.911099951553 69.3692218352873 7.03353860751193 6.09668042790844e-12 241.183427745013 217.911058449213 1.10679755979995 0.268872441150542 ATL2 essential 4.48995057102951e-07 1 7.27333975049477e-08 7.03353860751193 1.10679755979995 9.05835261948247e-07 65.6101855521365 38.7185065482613 1.6945432921168 0.0907312774772412 -558.207619497149 121.277222840583 -4.60274078200903 5.18870602314585e-06 YPEL5 other 0.00607906044293469 0.063717309964231 1 1.6945432921168 -4.60274078200903 4.21088884818933e-18 245.493637143921 26.6826739951242 9.20048857130215 7.58976961393576e-19 72.8303936523602 82.7678239444891 0.879936069132448 0.379282487804747 FAM98A other 4.7641996428414e-14 1 1.03076661126862e-14 9.20048857130215 0.879936069132448 6.38937422188201e-19 243.914234998738 28.2974761676401 8.61964627353121 7.30615652437677e-17 -173.53959546102 88.3159150346734 -1.96498666625248 0.049923300948084 YIPF4 other 7.36822635267433e-15 1 9.66020015653096e-13 8.61964627353121 -1.96498666625248 0.0015097510529994 66.612699858633 58.2128680495232 1.14429510330884 0.253005435991183 -658.33697419555 205.543545504836 -3.2029075521618 0.00144021622695183 AFTPH other 1 1 1 1.14429510330884 -3.2029075521618 2.000813098494e-13 150.170267249909 19.4964477994338 7.70244245489014 6.37047118870632e-14 -17.4823595637758 68.8399170100398 -0.253956720506013 0.799625127352066 LGALSL other 1.94579073828542e-09 1 7.96882240995274e-10 7.70244245489014 -0.253956720506013 0.0628446331636249 -23.509794180202 10.158531947832 -2.31429051962763 0.0210213254688129 -28.478833442685 33.1393399178957 -0.859366345655729 0.390514879722277 CNRIP1 other 1 1 1 -2.31429051962763 -0.859366345655729 1.79558495189334e-07 128.330418148505 23.8252263022725 5.38632525544005 1.07426763997264e-07 228.798199010214 87.4455846194083 2.61646371290236 0.00913289684961563 BCL11A og 0.00127558354982503 1 0.00109446387160412 5.38632525544005 2.61646371290236 1.971036754912e-09 73.5827789049899 11.4099833635911 6.44898213785223 2.48859659359929e-10 40.8509540772387 39.3373596454736 1.03847727568414 0.299509259894594 CRIPT other 1.59082376488947e-05 1 2.832022923516e-06 6.44898213785223 1.03847727568414 9.83600875661978e-29 2139.05923286613 178.087778055874 12.0112635253106 1.20976564998873e-29 362.589186011678 619.945343180554 0.584872827903598 0.558875726318882 EPCAM other 1.32992674398256e-24 1 1.77557304448846e-25 12.0112635253106 0.584872827903598 9.01826670203708e-15 155.933986365054 29.8364462815648 5.22629219624596 2.48314460200973e-07 -200.509479321605 68.3566417326281 -2.93328452421468 0.0034977380558246 SLC17A5 other 9.2294321941619e-11 1 0.00248066145740772 5.22629219624596 -2.93328452421468 5.3958570403254e-08 598.850636061624 154.591178290008 3.87376978871458 0.000120266832470788 -739.0647282763 362.010322893593 -2.04155705386759 0.0416791728829237 OGFRL1 other 0.000398807793850451 1 0.985706958930575 3.87376978871458 -2.04155705386759 4.50707651545956e-11 166.667316087518 37.7804690370143 4.41146762694318 1.23733493267834e-05 -239.39846370491 72.875576996408 -3.28503009611451 0.00108511126434695 SLF2 other 3.95450893466422e-07 1 0.11066723637875 4.41146762694318 -3.28503009611451 1.87120219885847e-11 218.402550071674 47.2767501383805 4.6196608149334 4.803407111002e-06 -302.702800061085 90.4655720907641 -3.34605522371962 0.000876285876773804 IDE other 1.67285476577947e-07 1 0.0442537897136615 4.6196608149334 -3.34605522371962 0.102726385064357 4.80419167256951 2.98749532828412 1.60810014565908 0.108393426133449 11.4670556689993 6.08584472614325 1.88421758769818 0.0600685164705453 ELOVL3 other 1 1 1 1.60810014565908 1.88421758769818 0.00374468619815307 590.755374295813 176.761634029848 3.34210179453342 0.000889586326643994 346.599664405778 342.007182718664 1.01342802700987 0.311313855278516 IFIT3 other 1 1 1 3.34210179453342 1.01342802700987 1.73363472854103e-05 730.215887935671 154.904102656483 4.71398675317855 3.10218150251861e-06 419.230439083308 309.178210244825 1.35595079210575 0.175686859568205 IFIT2 other 0.103185939042762 1 0.0289433534184986 4.71398675317855 1.35595079210575 0.0450842531103395 790.16962917599 370.59411876754 2.13216991085505 0.0334393347411979 -214.8277211109 686.565118938901 -0.312902178081694 0.754474681578133 GPAM other 1 1 1 2.13216991085505 -0.312902178081694 4.93663789553165e-06 76.5089295983602 18.3281902721594 4.17438538460491 3.47966883008224e-05 -32.2693184345821 35.9631192155223 -0.897289199004018 0.369962271820655 CUTC other 0.0308342402954907 1 0.299947453153089 4.17438538460491 -0.897289199004018 0.186000913108663 -11.2836606228689 103.509422000389 -0.109010951899881 0.913234001378346 -343.351850789029 197.649189346634 -1.7371781383169 0.0829217271510089 PPP1R3C other 1 1 1 -0.109010951899881 -1.7371781383169 0.22308445219775 2.01871667201233 6.61696882785409 0.305081786620265 0.760420337229433 21.9545548920876 13.0121695731471 1.68723246101823 0.092130860055705 CNNM1 other 1 1 1 0.305081786620265 1.68723246101823 9.54286006244964e-07 164.538144971612 55.2416512150504 2.97851605360384 0.0030256722143162 -288.139822869205 103.064313632871 -2.79572834391153 0.00536127659380351 MXI1 other 0.00638512766778506 1 1 2.97851605360384 -2.79572834391153 1.14804743441776e-09 123.386501777555 19.7577579435792 6.2449647439705 8.54906063081999e-10 30.0691772675356 36.8620364632512 0.815722085715813 0.415016115257528 SMNDC1 essential 9.36117878024244e-06 1 9.54246147612127e-06 6.2449647439705 0.815722085715813 2.69738049638476e-121 99.5913926415667 3.27526536376855 30.4071217383669 1.73995846609824e-119 8.02725147246391 12.0555134394883 0.665857287021083 0.505784045289352 C10orf88 other 4.22140047684216e-117 1 2.72286100359714e-115 30.4071217383669 0.665857287021083 1.14156616449466e-07 128.902553378636 25.3380538125192 5.08731074345367 5.00780879738794e-07 219.854020615678 49.338136369062 4.45606658044627 1.01400295654223e-05 HELLS other 0.000822384264901956 0.122390156854647 0.00491215964935784 5.08731074345367 4.45606658044627 1.10111850134049e-20 101.340916185422 35.4203378757977 2.86109400031067 0.00438357524752692 -524.866451780453 68.7807927252587 -7.63100323482756 1.04462721287823e-13 TCTN3 other 1.32123208975846e-16 1.5510624856816e-09 1 2.86109400031067 -7.63100323482756 3.29470503713337e-24 75.8918055887161 9.49865683189664 7.98974075301576 8.19941112294208e-15 -67.8000754227848 17.6498839685754 -3.84138929998062 0.000136837281180712 FAM45A other 4.2070088619156e-20 1 1.04517893584143e-10 7.98974075301576 -3.84138929998062 0.177613105047668 35.6989092883578 19.8361078417691 1.79969324492107 0.0724600204393452 11.7357554997319 38.0705077680922 0.308263697747892 0.757999040877649 AVPI1 other 1 1 1 1.79969324492107 0.308263697747892 6.58838342699958e-37 219.443238989035 19.2309250393014 11.4109559753662 3.64968644663597e-27 -372.588529982082 69.2665877893868 -5.37905131280584 1.11788271403971e-07 WDR11 other 9.50308425510419e-33 0.00147705843006067 5.29131541033282e-23 11.4109559753662 -5.37905131280584 5.34715745926973e-32 110.980170524472 15.8333927469303 7.00924762609635 7.12299120312758e-12 -245.347872541466 32.2542997251163 -7.60667181220539 1.2449642051486e-13 C10orf76 other 7.45286806673015e-28 1.84677990191743e-09 8.48205792468433e-08 7.00924762609635 -7.60667181220539 0.297102149166159 62.1287966160617 60.7802811390385 1.02218672654604 0.307146874953367 -92.0474557547963 123.815876771923 -0.743422072795671 0.45754712704875 KCNIP2 other 1 1 1 1.02218672654604 -0.743422072795671 0.431302593815703 0.590782107505744 3.34434968397351 0.176650818045983 0.859848419836893 8.77437518912473 6.92984908112377 1.26617118012357 0.20599372718161 CFAP58 other 1 1 1 0.176650818045983 1.26617118012357 9.04224164442271e-08 278.08509516771 53.4868589805176 5.19912929022438 2.83659082804626e-07 -25.3260583522491 105.181102872932 -0.240785251917783 0.80981211222648 GOT1 other 0.000655743364053535 1 0.00282439348748566 5.19912929022438 -0.240785251917783 1.13953914342702e-12 3.33408965102697 2.13235607456913 1.56357078012904 0.118500982110514 -28.4189217527439 4.40021242187176 -6.45853404973914 2.35030467620418e-10 C10orf95 other 1.07447145833734e-08 3.33719760974231e-06 1 1.56357078012904 -6.45853404973914 2.25691380647772e-52 568.662014745826 33.2220777850578 17.1169912497644 2.09587815401621e-52 42.5065401662399 138.68566320805 0.306495561134345 0.759350277959487 GNA13 other 3.428026380659e-48 1 3.2192688445689e-48 17.1169912497644 0.306495561134345 0.247128646199537 5.28033619283034 8.0410761337698 0.656670339266496 0.511680640750805 -43.0340310833153 31.8653450970077 -1.35049631354397 0.177438673629501 HOXB8 other 1 1 1 0.656670339266496 -1.35049631354397 1.40907299675468e-36 230.396758126249 30.5683612137235 7.53709878378476 2.1162209670593e-13 -578.888858475856 73.9078289494408 -7.83257831686363 2.65755859990715e-14 KANSL1 essential 2.02836057882836e-32 3.96481167520148e-10 2.61649560367212e-09 7.53709878378476 -7.83257831686363 0.0240898162923457 -3.93527047432917 11.6093758356042 -0.338973475409445 0.734764991842386 -123.689102864559 45.4457868966594 -2.72168469974608 0.00671033673565266 HOXB5 other 1 1 1 -0.338973475409445 -2.72168469974608 2.67421213393842e-06 24.7144690948721 9.08109878078517 2.72152849467576 0.00671021380121992 108.990090095405 21.5087402938968 5.0672465521531 5.57070734875556e-07 CRHR1 other 0.0171684418998846 0.00715390237727189 1 2.72152849467576 5.0672465521531 5.86384839391114e-05 94.6828851418577 40.2543492595386 2.35211565665595 0.0190360405796749 -491.946356326419 157.452332799161 -3.1244145296591 0.0018802266822876 HOXB3 other 0.328434148542963 1 1 2.35211565665595 -3.1244145296591 7.49766691943829e-05 209.350839351459 277.488566751477 0.754448523059172 0.450909430224063 -2841.30641784995 747.4025320973 -3.80157451417365 0.000160195039943138 DUSP1 other 0.414620980644937 1 1 0.754448523059172 -3.80157451417365 2.05837796305655e-14 374.057238620921 139.603635110709 2.67942334255325 0.00759700372715873 -2210.36233148113 356.222494737888 -6.20500491724289 1.08063946707118e-09 PANK3 other 2.07793255370558e-10 1.51289525389965e-05 1 2.67942334255325 -6.20500491724289 1.64108308936005e-08 0.907909894181782 20.6129569555664 0.0440455921068911 0.96488434388428 -322.196747112929 56.924779497134 -5.66004383256593 2.45940181790139e-08 MSX2 other 0.00012529669387264 0.000332068433453046 1 0.0440455921068911 -5.66004383256593 0.0166012926396951 -38.8201423599748 17.8845396305058 -2.1705977991046 0.0304081943062426 -109.579221327948 43.1306907490869 -2.54063219078559 0.0113515303812581 TEK other 1 1 1 -2.1705977991046 -2.54063219078559 2.46606737901118e-49 149.229406196978 10.912291927905 13.6753495217048 8.71126412544802e-37 -102.708742619738 26.811381726321 -3.83078886676354 0.000142676752923329 RCL1 other 3.72178888840367e-45 1 1.30712518202347e-32 13.6753495217048 -3.83078886676354 2.05498712115347e-42 89.951368054374 9.12293864119366 9.85991154738323 3.73532614040403e-21 -157.617308900834 21.7929774604095 -7.23248161877702 1.68784078172404e-12 CAAP1 other 3.04055894445868e-38 2.4740370178511e-08 5.18986213947736e-17 9.85991154738323 -7.23248161877702 0.0658056196983519 44.7724139685713 19.7575328391865 2.26609335958036 0.0238519362700125 13.3265460329683 47.7999271845509 0.278798458866178 0.780509279463146 MOB3B other 1 1 1 2.26609335958036 0.278798458866178 8.1365253716469e-10 35.962173062821 5.45189960612243 6.59626472623154 1.0022630227675e-10 31.2069874637709 13.4176578274197 2.32581482291177 0.0203957768585339 CD274 other 6.69229211817958e-06 1 1.15460700222816e-06 6.59626472623154 2.32581482291177 0.00810794103408049 -227.939872632624 164.794539311773 -1.38317612697947 0.167181411274044 -1147.29248653728 368.876797425478 -3.11023218197685 0.00196790744031102 GRIA2 other 1 1 1 -1.38317612697947 -3.11023218197685 2.7779502711664e-33 159.413499701757 20.1523298752787 7.9104252802706 1.43744500899993e-14 -309.155698491209 50.1995958707528 -6.15852962815043 1.42631306862185e-09 NUP43 essential 3.91357634201922e-29 1.99127567510297e-05 1.82383022741912e-10 7.9104252802706 -6.15852962815043 2.83306260766944e-09 220.049467135464 34.468785626693 6.38402145984091 3.69451462774316e-10 204.222990500998 74.234296626112 2.7510598171299 0.00613786003227703 MTHFD1L other 2.26361702352788e-05 1 4.18256001006803e-06 6.38402145984091 2.7510598171299 3.71776437282125e-14 266.644906224242 44.0265462729454 6.05645749660126 2.59454279932067e-09 -252.515142898719 109.670437322389 -2.30249052583261 0.0216834325663634 LRP11 other 3.7166490435094e-10 1 2.83894873101667e-05 6.05645749660126 -2.30249052583261 2.56325086033546e-05 -54.3338128238546 39.9212365745017 -1.36102529595886 0.174067158421071 -396.569999687152 86.6310360532235 -4.57768967975301 5.82653621780198e-06 CCDC170 other 0.149796380278004 0.0713342829145496 1 -1.36102529595886 -4.57768967975301 9.50446793319455e-36 332.906901854967 37.320614819475 8.92018803723583 7.04561814386403e-18 -525.221073405954 92.9659147691855 -5.64960904983258 2.59349541933012e-08 PCMT1 other 1.36322583565809e-31 0.000349888467021827 9.46085604358062e-14 8.92018803723583 -5.64960904983258 0.00358550877638948 100.264211358669 30.1450858461322 3.32605492883456 0.000940170217258811 68.2844635145128 64.5513311221922 1.05783199706996 0.290600679966848 PLEKHG1 other 1 1 1 3.32605492883456 1.05783199706996 0.0304999160768481 -29.4304537498734 11.1787698818372 -2.63270950748264 0.00871185956227806 -35.7558296707141 24.4704160533474 -1.46118601305199 0.144542808618475 MYCT1 other 1 1 1 -2.63270950748264 -1.46118601305199 1.51316777374528e-21 161.870135704923 26.5592020618838 6.09469122331917 2.07795504682985e-09 -352.901350405542 63.269117362562 -5.57778210154648 3.8434769698766e-08 CYSTM1 other 1.84727521818824e-17 0.000515794609357439 2.28201023242855e-05 6.09469122331917 -5.57778210154648 1.2063718730378e-36 175.714530787095 20.8397097874873 8.43171678391599 3.1305137164003e-16 -364.855956589908 49.4705849981887 -7.3752100688372 6.22971185512408e-13 WDR55 essential 1.73717549717443e-32 9.17075882192816e-09 4.09032922184864e-12 8.43171678391599 -7.3752100688372 0.783503831738477 6.44644056682544 14.5470410468649 0.443144454329753 0.657838073368247 -11.9873511898805 34.3885102662255 -0.348585940393407 0.727535546792012 ARAP3 other 1 1 1 0.443144454329753 -0.348585940393407 0.402757594757661 11.9152066793707 9.79008349133802 1.21706895451024 0.224110593081206 -2.64555526338222 23.8343962307709 -0.110997368583087 0.911659751931999 PCDHB8 other 1 1 1 1.21706895451024 -0.110997368583087 0.00176757619440226 1.2310315175867 8.20956851562949 0.149950818394784 0.880859511091088 67.8796024986009 19.9865618161784 3.39626210465348 0.000733514310696551 PCDHB10 other 1 1 1 0.149950818394784 3.39626210465348 0.759942232361703 8.43892928358764 11.6072301903957 0.727040744877307 0.467516643192249 11.1300036832687 28.2583211618604 0.39386641617941 0.693835431619209 PCDHB14 other 1 1 1 0.727040744877307 0.39386641617941 0.143157300381258 0.924409301030329 2.41629645821471 0.382572799743842 0.702187351766524 -9.84636718193222 5.88258182343924 -1.67381729272327 0.0947466702090483 PCDHB12 other 1 1 1 0.382572799743842 -1.67381729272327 0.0843466496179397 -20.3485952296257 14.5845490550146 -1.39521593385359 0.16351900026582 -193.369731915892 104.918406892159 -1.84304868558144 0.065864744659318 TNN other 1 1 1 -1.39521593385359 -1.84304868558144 3.44299748009409e-19 103.348588638452 11.0166973913863 9.38108626994317 1.74521864965822e-19 -99.946033811193 79.2698285090765 -1.26083322861925 0.207908423616429 MRPS14 essential 4.00041877212132e-15 1 2.38745911273244e-15 9.38108626994317 -1.26083322861925 4.30062389462259e-08 38.6477778698965 6.5774897857631 5.87576402680992 7.38321647326361e-09 52.1244345827147 48.3974430231516 1.07700802618395 0.281959371527964 CENPL other 0.000319364330414673 1 7.9458175685263e-05 5.87576402680992 1.07700802618395 1.88737092025404e-07 30.6124574779631 5.43197624791435 5.63560223403352 2.81021383307963e-08 3.43674704825629 38.1625585053523 0.090055467527794 0.928276467385378 SEC16B other 0.00133833471955214 1 0.000295325371718338 5.63560223403352 0.090055467527794 5.2197639914127e-14 44.7958119628779 5.6024850334298 7.99570399484927 7.82786912463405e-15 -15.4205186555018 41.3157066329376 -0.373236231743602 0.709118561638257 GORAB other 5.18844540746423e-10 1 9.98209870773334e-11 7.99570399484927 -0.373236231743602 2.10516173742866e-25 359.551344018958 35.1885187958226 10.217859583838 1.51629592022317e-22 51.0768488759437 74.2046687737917 0.688323925164983 0.49154115611474 ACAT2 other 2.73544716161481e-21 1 2.13191206383378e-18 10.217859583838 0.688323925164983 2.93859995429316e-45 1708.83884348482 125.431266711473 13.6237071368786 1.3635931101828e-36 -156.678936845574 264.506319638182 -0.5923447767142 0.553864954585515 TCP1 essential 4.39203149168656e-41 1 2.0453896652742e-32 13.6237071368786 -0.5923447767142 3.27497752721278e-36 301.597751585668 56.4988727228163 5.33811980754568 1.38510577079174e-07 -794.596484863017 107.93195764137 -7.36201308886897 6.80009944882632e-13 SNX19 other 4.70909018637926e-32 1.00063463389479e-08 0.0014020040611954 5.33811980754568 -7.36201308886897 0.576626872562507 8.00203429171515 7.87997978900896 1.01548918981701 0.310327463854525 12.0610734072362 15.0495618585245 0.801423557749919 0.423238979626235 KCNJ5 other 1 1 1 1.01548918981701 0.801423557749919 1.12224704183473e-18 9.79901018885889 6.89837822607276 1.42048027343921 0.15605041940518 -83.9235330808518 12.4329480097813 -6.75009121045363 3.85421730714968e-11 MSANTD2 other 1.28732958168862e-14 5.54776039191125e-07 1 1.42048027343921 -6.75009121045363 0.00731379724031086 -2.98478669094104 2.51494093084619 -1.18682178747505 0.235819776328374 -14.7492330819195 4.80315433830129 -3.07073894426133 0.00224276921270143 TP53AIP1 other 1 1 1 -1.18682178747505 -3.07073894426133 4.2260589840846e-15 34.3064248284009 6.92981517635619 4.95055408482622 9.9075382647656e-07 -72.4329108141327 16.0147048145149 -4.52290015039699 7.50445293737694e-06 SLC10A7 other 4.37777450161324e-11 0.0912991744361279 0.00953303331835746 4.95055408482622 -4.52290015039699 1.05895969001808e-64 199.421230660373 10.1808691535761 19.5878394714782 9.88034988754063e-65 377.29841917697 118.828563560062 3.17514920548765 0.00158432812887562 NUDCD1 other 1.63450428154291e-60 1 1.52997218008567e-60 19.5878394714782 3.17514920548765 1.67603087748375e-63 319.315202552882 16.305863753302 19.5828450049584 9.82823989035883e-65 116.850199669247 190.669210940576 0.612842519737833 0.540241863726133 ENY2 other 2.58427200999219e-59 1 1.52200122942097e-60 19.5828450049584 0.612842519737833 4.52742474217366e-26 185.722564119031 16.5289550287971 11.2361951372885 1.68184717805339e-26 49.1864112965083 59.8339953168593 0.822047918345329 0.411407797208018 MASTL essential 5.93998126173185e-22 1 2.43060554172276e-22 11.2361951372885 0.822047918345329 9.64315954136824e-05 -115.335816686908 92.878309999318 -1.24179495393225 0.214852303720151 -1559.03387209186 360.302282994565 -4.3270163573051 1.8016984833355e-05 KIAA1217 other 0.524877173836673 0.214131864744425 1 -1.24179495393225 -4.3270163573051 0.177435773929266 -144.843428982176 154.530501139458 -0.937312879426049 0.349016652290272 -1059.83086043419 599.922530670894 -1.76661286457933 0.0778579665639068 PLXDC2 other 1 1 1 -0.937312879426049 -1.76661286457933 4.01178401901225e-06 39.7475881212251 18.3748631060968 2.16315016290036 0.0309668781378408 -267.18233350178 67.0511122141513 -3.98475617598168 7.68069778100616e-05 EPC1 other 0.0252983100238912 0.872911302811351 1 2.16315016290036 -3.98475617598168 0.0943568989211192 6.92130522569775 3.24348769173957 2.13390827513382 0.0333220623311405 2.39025613972099 12.4561182202913 0.191894143700981 0.847900761927526 IQSEC3 other 1 1 1 2.13390827513382 0.191894143700981 2.132737428913e-47 123.136979286798 7.86246277753566 15.6613751658857 1.48354103356063e-45 -1.43881739558282 30.2303437037016 -0.047595138503392 0.962057215403226 CCDC77 other 3.20358489197022e-43 1 2.26150995155982e-41 15.6613751658857 -0.047595138503392 1.95860239859367e-25 82.6055024544896 16.4934473246422 5.00838307653684 7.43777198562963e-07 -168.731200779353 26.9143133951448 -6.26919952599612 7.41447770549176e-10 TAF12 other 2.54618311817178e-21 1.0418824071757e-05 0.00721463882606074 5.00838307653684 -6.26919952599612 1.18175370130994e-05 -8.42881374720198 10.5750459563181 -0.797047481591905 0.425771184749165 -90.3194732089437 20.1778330488858 -4.47617308509404 9.26174539688784e-06 ENOX1 other 0.0713779235591201 0.112057857556946 1 -0.797047481591905 -4.47617308509404 0.134829064355627 -12.287401141426 13.5161250766946 -0.909091997277586 0.363703405362292 -51.755963357317 25.876428810573 -2.00012002182348 0.0459830226821569 TNFSF11 other 1 1 1 -0.909091997277586 -2.00012002182348 3.29670395992604e-36 27.4076947908875 3.55337125994208 7.71315260520632 5.8905961146781e-14 -38.2789139024753 6.71358993378155 -5.70170568653036 1.94746896818062e-08 MTRF1 other 4.74000095358166e-32 0.000263687298291655 7.37502633557698e-10 7.71315260520632 -5.70170568653036 0.572764657160139 1.48428503091341 6.07431875848619 0.244354155573376 0.80705022722278 -9.04880450199123 11.9238428894251 -0.758883238055439 0.448256610371868 SOHLH2 other 1 1 1 0.244354155573376 -0.758883238055439 1.80429182586914e-16 71.2629272122199 33.0812301238515 2.15418008778457 0.0316637060805082 -390.971134731642 63.0458092152953 -6.20138181423786 1.10677816121546e-09 DNAJC15 other 1.95043946376455e-12 1.54893603662103e-05 1 2.15418008778457 -6.20138181423786 1.37320762501697e-27 389.047992340468 37.081192341218 10.4917875552782 1.44364646188354e-23 62.6764781865054 71.1561919303507 0.880829573452364 0.3788012038783 PROSER1 other 1.83446806626018e-23 1 2.04838996476656e-19 10.4917875552782 0.880829573452364 8.13669118448773e-31 309.285975196841 47.8621306313567 6.46201853358809 2.30707654320457e-10 -536.857784992254 91.7467807534412 -5.85151632115569 8.44503118620223e-09 UFM1 other 1.12115467831056e-26 0.000115753592360375 2.62729876740137e-06 6.46201853358809 -5.85151632115569 1.7956569470337e-37 56.9638819163179 7.72347402805852 7.37542221406771 6.14948708843709e-13 -92.6715671342771 14.592406392526 -6.35067065989488 4.52879260642525e-10 WBP4 other 2.59921343083129e-33 6.39284364322988e-06 7.50852373498169e-09 7.37542221406771 -6.35067065989488 6.16623353448533e-18 164.862472222359 73.1596864294168 2.25346061838873 0.0246267706680608 -890.443077604946 138.130647000136 -6.44638316653992 2.52504671088571e-10 ELF1 other 6.95057844007186e-14 3.58405130143117e-06 1 2.25346061838873 -6.44638316653992 0.336972775360101 1.81314466404961 6.68573657499777 0.271195947329141 0.786344739709917 17.876905246403 12.9192207275143 1.38374485763915 0.167012550922303 SMAD9 other 1 1 1 0.271195947329141 1.38374485763915 8.25119936250201e-16 1128.19942711904 147.46211671654 7.65077466836941 9.46368637158049e-14 85.7902097923253 301.854290038738 0.284210669264683 0.776359732575584 HSPH1 other 8.74709644418838e-12 1 1.17879677444407e-09 7.65077466836941 0.284210669264683 1.12286591027815e-24 65.0470075767225 14.1308443630568 4.60319326329706 5.18395728738697e-06 -164.048859656795 26.6982219226928 -6.14456124201132 1.55055950511022e-09 KBTBD7 other 1.44456699357284e-20 2.16272039772773e-05 0.0476820391293854 4.60319326329706 -6.14456124201132 1.1103814488889e-45 121.55062768817 17.9495324506405 6.77179909963799 3.35150040338238e-11 -303.859973474797 34.3461867775587 -8.84697842711712 1.30385859900968e-17 ALG5 other 1.66146376197246e-41 1.98994899380858e-13 3.91388217106994e-07 6.77179909963799 -8.84697842711712 4.08938289099817e-30 113.35789878869 12.49099218984 9.07517169700055 2.15538506783285e-18 -61.8004422083584 23.9013440583496 -2.58564715262401 0.00998241944289564 EXOSC8 essential 5.59836517777649e-26 1 2.91041645709469e-14 9.07517169700055 -2.58564715262401 7.50590388181641e-10 292.07692805627 64.5180272871161 4.52705918543477 7.34992196528002e-06 -437.231400065629 151.217177257826 -2.89141358140913 0.00398815734819601 ETF1 essential 6.18711656978127e-06 1 0.0668842898840482 4.52705918543477 -2.89141358140913 0.0348525005131198 -37.3923362282823 279.013409800655 -0.134016269164259 0.893439182848957 1521.96578894377 642.344653439823 2.36939123069443 0.0181648594831858 TGFBI other 1 1 1 -0.134016269164259 2.36939123069443 0.00233367461347545 91.1936996258382 28.9947399566761 3.14518080734987 0.00175053147328282 -20.7870371549332 68.1838445916611 -0.304867484070786 0.760583681967563 FAM53C other 1 1 1 3.14518080734987 -0.304867484070786 1.61586580477439e-13 293.665449553477 72.3971057318062 4.05631477370595 5.71473481904521e-05 -839.387495274948 170.692640048233 -4.91753771596573 1.16241167719802e-06 SIL1 other 1.57756978520124e-09 0.0147161318333269 0.483123681602082 4.05631477370595 -4.91753771596573 2.13153688804953e-22 324.352309037206 51.8308007480331 6.25790657979589 7.92280610743077e-10 -687.432159829761 121.988894257541 -5.63520281099083 2.81161313324287e-08 PAIP2 other 2.64523727806946e-18 0.000378921101967142 8.85452810566463e-06 6.25790657979589 -5.63520281099083 0.216185117018139 232.052810059902 137.430486388676 1.68851043285708 0.0918853279000387 48.7931219328638 317.776514816522 0.153545399542934 0.878025026570766 MYOT other 1 1 1 1.68851043285708 0.153545399542934 5.94007107393049e-17 232.494016490805 66.1666751752602 3.51376302156609 0.000478584059534547 -998.769102998091 155.597129135765 -6.41894300071965 2.9905565942992e-10 KDM3B other 6.51506995388697e-13 4.23612341582482e-06 1 3.51376302156609 -6.41894300071965 0.00280412729251777 157.220630847913 652.552129144555 0.240931909997776 0.809698499478524 -4784.36858178163 1529.4499093051 -3.12816297720752 0.00185302495480271 EGR1 other 1 1 1 0.240931909997776 -3.12816297720752 1.51576789190466e-08 734.969008597665 147.431541386126 4.98515447703803 8.34051392322223e-07 -1912.51076213145 601.77060360135 -3.17813922894515 0.00156661096136699 SERP1 other 0.000115956243730706 1 0.00806861316932518 4.98515447703803 -3.17813922894515 0.00054706955230667 52.6117253611272 19.0166099060171 2.76661958262499 0.00585638185381064 -157.052421505428 66.9880616284367 -2.34448374363409 0.0194114933708275 PLS1 other 1 1 1 2.76661958262499 -2.34448374363409 1.59930254917094e-26 86.3536017869331 8.29912134578968 10.4051499175563 3.08687143003983e-23 -105.649163692782 40.7802434701986 -2.59069477527736 0.00983659401466868 ZFP30 other 2.10963999261138e-22 1 4.36854044779237e-19 10.4051499175563 -2.59069477527736 1.77871572369805e-12 51.3379002846698 9.0662638763538 5.66251997347738 2.43035413501603e-08 -79.9408413770237 24.3672540966545 -3.28066679404797 0.00110270412043317 NR2C1 other 1.66505578895375e-08 1 0.000256110718747989 5.66251997347738 -3.28066679404797 2.3620539816105e-06 167.617551583744 36.9422997686546 4.53727982917747 7.02292060165277e-06 -93.6986979817752 89.6990343363613 -1.04458981832977 0.296678243598622 UTP20 essential 0.0152541446132406 1 0.0639998754428617 4.53727982917747 -1.04458981832977 6.94510675290399e-07 529.218789309038 99.1245429129907 5.33892791590045 1.37734375854446e-07 564.920771227522 243.296603172688 2.32194269817466 0.020605702167715 TMPO other 0.00470808786779362 1 0.00139442282115042 5.33892791590045 2.32194269817466 4.50219689042085e-16 251.0367272888 78.4437302482727 3.20021404507759 0.00145348980216326 -1303.07941999697 190.930132596609 -6.82490187523239 2.35839574860238e-11 ARL1 other 4.80969693803659e-12 3.40575930055669e-07 1 3.20021404507759 -6.82490187523239 0.00123565633357465 -58.1788898326446 21.7560624293383 -2.67414611543814 0.00771599864426207 -169.137544368667 52.0657663594035 -3.24853653744635 0.00123118557669085 GLT8D2 other 1 1 1 -2.67414611543814 -3.24853653744635 2.82748829813905e-20 34.1566518674702 14.4367097033556 2.36595821134583 0.0183317558018458 -280.838104615363 33.2823807587877 -8.43804133636719 2.90702982144763e-16 MTERF2 other 3.36697306542398e-16 4.40211525861815e-12 1 2.36595821134583 -8.43804133636719 0.0315524237913389 -26.7659740830578 36.900695446198 -0.725351480762285 0.468552397015832 -251.006493319563 95.1657567960419 -2.63757155693635 0.0085922294274597 SOCS2 other 1 1 1 -0.725351480762285 -2.63757155693635 8.59164382935561e-12 93.9366672454655 17.5011128280675 5.36746823863762 1.18152802258804e-07 -125.714235125358 41.882985696297 -3.00155858125636 0.00280860733035431 NFYB essential 7.813240898416e-08 1 0.00120090508215849 5.36746823863762 -3.00155858125636 1.06122710575952e-18 56.3770162169802 10.7773922365524 5.23104429898848 2.40912453245565e-07 -155.545920701262 26.0353387899288 -5.97441508083743 4.17606834599186e-09 WASHC3 other 1.21818259470135e-14 5.76756799264936e-05 0.00240780666232596 5.23104429898848 -5.97441508083743 1.33403302824711e-06 71.4186267177227 18.40870678964 3.87961129121332 0.000117541115834535 -100.762381717759 44.9632031135331 -2.24099652027307 0.0254319163021987 APAF1 other 0.00880862008551568 1 0.964307314306527 3.87961129121332 -2.24099652027307 6.9668140584809e-17 392.890339123525 374.614660677055 1.04878527288131 0.29474786312127 -4791.11596609963 762.288712468115 -6.28517238644017 6.77220682314091e-10 DUSP4 other 7.62657134981905e-13 9.52443167606538e-06 1 1.04878527288131 -6.28517238644017 2.41280092358936e-27 132.27130271986 38.278918515022 3.45546080848528 0.000592396865901051 -491.329803385957 77.4521265416595 -6.34365801591882 4.73744509894796e-10 TNFRSF10B other 3.21385083022103e-23 6.68358754559578e-06 1 3.45546080848528 -6.34365801591882 5.71062969963802e-28 401.806858251695 96.8956716104402 4.14679883604214 3.92685642094025e-05 -1188.84569200896 196.389600194216 -6.05350635081118 2.68742531668972e-09 SORBS3 other 7.65852549018455e-24 3.72880262690699e-05 0.336806475224045 4.14679883604214 -6.05350635081118 9.25118648096467e-18 83.8479790934647 25.6648087984431 3.26704086330661 0.00115504361925628 -255.892405412053 54.5257813419881 -4.69305343479783 3.40715138700135e-06 PTK2B other 1.03807563502905e-13 0.0422009770793987 1 3.26704086330661 -4.69305343479783 2.64940017449715e-34 41.1282815747094 9.2192348911442 4.46113826801575 9.93593008914966e-06 -130.353368353978 18.6676655539596 -6.98284249721461 8.57929726415101e-12 PPP3CC other 3.7618833077685e-30 1.24640030653586e-07 0.089562473823595 4.46113826801575 -6.98284249721461 2.07880960956103e-08 52.5583176431109 27.4222017259145 1.91663376152041 0.0558239591266439 -180.661908458964 55.6375717751229 -3.24712065417173 0.00123982593596354 PDLIM2 other 0.000157823225557874 1 1 1.91663376152041 -3.24712065417173 3.17213097664078e-41 151.745516072804 35.5354363029583 4.27025898258554 2.30490312818301e-05 -661.563293948551 76.2089271718085 -8.68091598320359 4.59484701807437e-17 EPHX2 other 4.66937679761522e-37 6.99473561561461e-13 0.201679023716013 4.27025898258554 -8.68091598320359 2.24079987477114e-18 48.9169947980354 19.7403058978472 2.47802617908622 0.0135135183277118 -209.634945200563 31.9694575553904 -6.55735071004407 1.27514793187289e-10 UBIAD1 other 2.55428777725162e-14 1.81950858398943e-06 1 2.47802617908622 -6.55735071004407 0.000206037743227682 255.725374328408 63.0565865969097 4.05549028467299 5.73292673010882e-05 126.762025060575 101.85892643503 1.24448616824397 0.213855596857552 TARDBP other 1 1 0.484489637961497 4.05549028467299 1.24448616824397 0.0378644244751756 9.0050189500543 4.03556943903313 2.23141221730825 0.0260604840366987 0.664915506523066 6.38037601457992 0.104212589509404 0.917039052427787 TNFRSF8 other 1 1 1 2.23141221730825 0.104212589509404 7.25554063925789e-71 386.585607721162 18.3933345178689 21.0177011322009 5.15220825197151e-72 -71.660754241544 243.826271875671 -0.293900873315589 0.768947210022105 ZNF706 other 1.12330280176991e-66 1 8.00395551943774e-68 21.0177011322009 -0.293900873315589 6.04224526888735e-48 808.862786249505 49.8684975645157 16.219914891221 1.13379660489446e-47 -552.434504852021 400.036172873274 -1.38096137877767 0.167920325516974 LYPLA1 other 9.09055800704102e-44 1 1.73232783261824e-43 16.219914891221 -1.38096137877767 0.00133415693111357 1536.42064310848 419.959448881357 3.65849761733195 0.000279564965546622 512.994087824181 4285.19368698224 0.119713162413773 0.904756609302963 CRISPLD1 other 1 1 1 3.65849761733195 0.119713162413773 4.62314715805241e-79 409.706098660586 18.2860382692662 22.4054052948795 1.20701019828123e-78 -252.146290374413 171.427664450203 -1.47086114241297 0.141924358820054 COPS5 essential 7.18945614548731e-75 1 1.87883207464456e-74 22.4054052948795 -1.47086114241297 1.03785229959876e-06 572.005617404322 122.149286733233 4.68284042176645 3.61213014746835e-06 3530.49961315157 1204.32698215512 2.93151250903124 0.00352106533982289 RDH10 other 0.00691520987222655 1 0.0335675254604234 4.68284042176645 2.93151250903124 2.52768217911732e-21 474.77638758011 47.3951357368085 10.0174074870595 1.12351123478069e-21 14.3007607228975 161.765210183771 0.0884044270498663 0.929590081867799 AKAP1 other 3.07265045693502e-17 1 1.5680846303834e-17 10.0174074870595 0.0884044270498663 6.14138562642895e-56 163.567611603105 9.70014342466076 16.8623910433392 4.7821914650092e-51 -104.024757257128 32.547645332325 -3.19607628124837 0.00147926113203629 COIL other 9.37973826724494e-52 1 7.33731636476362e-47 16.8623910433392 -3.19607628124837 0.00131373284920893 116.359661239322 83.6887760127051 1.39038550667364 0.165017104772734 1012.3037055441 280.90391252628 3.60373658180856 0.000344381914081556 SCPEP1 other 1 1 1 1.39038550667364 3.60373658180856 3.7555388343975e-68 288.584123961072 18.3181455364204 15.754003230693 5.15088617062891e-46 -805.341133670842 82.6268319140571 -9.74672651746474 9.89685494335249e-21 SPOP other 5.80531193021166e-64 1.52787646615476e-16 7.8592221191456e-42 15.754003230693 -9.74672651746474 0.055574918286092 -2.60149440364398 6.73641989450998 -0.386183528399726 0.69952437125338 -59.5992988295826 24.7303627862228 -2.40996459877188 0.0163127485263019 TBX2 other 1 1 1 -0.386183528399726 -2.40996459877188 3.58173343421765e-95 477.154276144987 18.7160646514877 25.4943699452897 1.12516764516972e-93 -6.31137678089086 84.5636430573236 -0.0746346367387759 0.940534061942415 SLC35B1 essential 5.5903695441269e-91 1 1.756836761168e-89 25.4943699452897 -0.0746346367387759 0.524094805191879 -0.666469520002135 33.5072727747843 -0.0198902943991217 0.984138473362337 -166.214493976816 148.68780552037 -1.11787576254224 0.264133283829028 TEX14 other 1 1 1 -0.0198902943991217 -1.11787576254224 9.89611008706312e-14 29.3789451226306 7.0222392023741 4.18370042317813 3.36664196550308e-05 -183.050328009769 31.6681415116745 -5.78026746351021 1.28690216864178e-08 FAM117A other 9.7357931036527e-10 0.000175404765585875 0.290574868042571 4.18370042317813 -5.78026746351021 2.45208848366417e-20 185.572600508098 18.6820963500042 9.93317864502161 2.13548984007148e-21 116.305755894699 70.7978978227364 1.64278544238567 0.101035354309596 NCAPH essential 2.92288947252769e-16 1 2.97302895534752e-17 9.93317864502161 1.64278544238567 4.12804677950276e-06 51.0493339780392 10.4945582539547 4.86436234310311 1.50499693282206e-06 72.0152718635546 23.7737986491941 3.02918658167385 0.00256835483281437 LRAT other 0.0259819264301904 1 0.0143200458158019 4.86436234310311 3.02918658167385 1.84521679055197e-24 65.5263204018525 6.39922631990316 10.2397254177508 1.26397601512289e-22 108.918955757777 14.5163711810551 7.50318067782147 2.55041503955083e-13 MND1 other 2.36538340380857e-20 3.77002351146404e-09 1.7784142532779e-18 10.2397254177508 7.50318067782147 6.02918384718557e-08 -22.7118207498245 10.0959548545449 -2.24959610824728 0.0248706857149723 -131.990030394251 22.5443272937415 -5.85468923842731 8.23886756205872e-09 TRIM6 other 0.000443627347475914 0.000112963113143387 1 -2.24959610824728 -5.85468923842731 0.00424251907535104 -165.700006813517 186.003772134146 -0.890842185146729 0.37344575257446 -1566.00542815856 496.034293873662 -3.15705072713665 0.0016907432569061 ABCC11 other 1 1 1 -0.890842185146729 -3.15705072713665 2.49028150812767e-15 86.4696490114026 22.4651208986673 3.84906225973315 0.000133660106268836 -240.031027276662 58.0243187581077 -4.13673150179161 4.12129171691437e-05 PAPD5 other 2.59786166927879e-11 0.477781348741882 1 3.84906225973315 -4.13673150179161 0.000867136702617602 53.6140394793299 25.4138928715901 2.10963506261035 0.035376412524811 -93.9714887170371 65.6347253929485 -1.4317343167727 0.152832411577044 ADCY7 other 1 1 1 2.10963506261035 -1.4317343167727 5.23809322746695e-36 201.358834327846 15.9085124612046 12.6573012290678 2.44501924674855e-32 -183.032311303271 72.0037187123889 -2.54198414437973 0.0113008150364603 CEP89 other 7.52347330261078e-32 1 3.62425202945537e-28 12.6573012290678 -2.54198414437973 0.110894975877886 -28.7281438605073 14.022942472963 -2.04865304952201 0.0409946252226653 0.575900718280745 61.3134131443521 0.00939273625046584 0.992509372626686 TSHZ3 other 1 1 1 -2.04865304952201 0.00939273625046584 5.16676263721442e-06 -127.232764106915 74.2301792803796 -1.71403013357055 0.0870949192003533 -770.333482332256 154.391765950714 -4.98947257704253 8.16860915596535e-07 ECHDC2 other 0.0321992647551203 0.010416610395687 1 -1.71403013357055 -4.98947257704253 0.0022051910088026 173.522904940042 51.709580789846 3.35572058967679 0.000846936390388526 18.8420239077766 161.911053161543 0.116372684507076 0.907400208934716 PLBD1 other 1 1 1 3.35572058967679 0.116372684507076 1.09523201369237e-39 198.166801479931 16.1228751080722 12.2910337115193 1.01754384384136e-30 -216.108681264682 56.611301685481 -3.81741233341233 0.000150817132474182 PYROXD1 essential 1.60188634322646e-35 1 1.50006313459093e-26 12.2910337115193 -3.81741233341233 0.777632810932267 22.362767719735 37.6950301165527 0.59325506971581 0.553264974102686 -25.3922478241093 131.964907733649 -0.192416667886888 0.847489960653592 KCNJ8 other 1 1 1 0.59325506971581 -0.192416667886888 0.000711526002886006 21.0915181315305 5.5187486591489 3.82179356846869 0.000147900201375299 16.5908995380377 17.8207223232864 0.930989173001047 0.352275184083402 BCL2L14 other 1 1 1 3.82179356846869 0.930989173001047 6.56048295160667e-17 134.199943262816 23.8448377871142 5.62805016586598 2.98884691056467e-08 -165.162443248728 48.6579506854022 -3.39435674791537 0.000740627945893917 PSPC1 other 7.18504092859962e-13 1 0.000313619706325551 5.62805016586598 -3.39435674791537 1.26838058177298e-29 95.5296409551464 7.86916916741543 12.1397366002391 3.5301128687221e-30 5.61756112313808 39.5256754978488 0.142124354672795 0.887034400736943 ZNF549 other 1.72956376130564e-25 1 5.19350205246396e-26 12.1397366002391 0.142124354672795 0.0322364182005298 45.9425216822906 23.8034978600658 1.93007439294737 0.0541507262385428 -119.934089435693 89.4233890972056 -1.34119373741607 0.180453359149981 A1BG other 1 1 1 1.93007439294737 -1.34119373741607 5.58261779694885e-08 236.928199052623 49.2540839673832 4.81032596625938 1.97376202960648e-06 -514.883416339209 216.074266431904 -2.38290021686351 0.0175330054765321 ZSCAN18 other 0.000412332150482642 1 0.0186540249418108 4.81032596625938 -2.38290021686351 1.71920829531418e-36 87.6518253038349 6.48690054364196 13.5121272037607 4.5092749174528e-36 -30.7874749641423 32.7552112194223 -0.939926009266179 0.347673439651717 ZNF211 other 2.47411265778664e-32 1 6.75624660881954e-32 13.5121272037607 -0.939926009266179 0.00814684855435988 -27.0700716847855 53.6761479567343 -0.504322175030245 0.614238820417212 -322.566300706534 107.610143700556 -2.99754548794333 0.00284569593696619 PDZRN3 other 1 1 1 -0.504322175030245 -2.99754548794333 0.000267786076695164 10.8747811562818 2.69578500476964 4.03399423063823 6.26845840760782e-05 -7.2589361557541 19.0395274503307 -0.381256109149286 0.703162072966292 LHX4 other 1 1 0.527992251672807 4.03399423063823 -0.381256109149286 4.44640370436746e-05 66.6891032275121 16.4581778394496 4.05203442799487 5.82004919841515e-05 -199.564183115409 117.44621428407 -1.69919638816725 0.0898560057470626 RNF2 other 0.25349567113672 1 0.491619555790128 4.05203442799487 -1.69919638816725 7.41963246222327e-12 104.179882313816 14.2091339704489 7.33189528161823 8.32638773377936e-13 60.0241340782987 101.397797782056 0.591966841403342 0.554120090871018 TRMT1L other 6.77041462177873e-08 1 1.01348791495562e-08 7.33189528161823 0.591966841403342 4.69821205962707e-29 76.074297237012 7.02525225991371 10.8286926109535 7.10292343001371e-25 -79.964996343003 23.3083222031438 -3.43074871052783 0.000647714493603664 SEC22A other 6.37500394370798e-25 1 1.01685451824076e-20 10.8286926109535 -3.43074871052783 0.0416249392015024 53.1843311871825 43.0965123469833 1.23407506294196 0.217705843782867 335.871353442974 140.387542566247 2.39245838557564 0.0170729866706165 CSTA other 1 1 1 1.23407506294196 2.39245838557564 0.0848193119626657 2.8743378568545 5.26872749974989 0.545546881479626 0.585601887877903 -34.2168541070444 16.7480945428196 -2.04302967239424 0.0415326451884706 POPDC2 other 1 1 1 0.545546881479626 -2.04302967239424 6.40735624467985e-17 132.187314369222 15.9429453423482 8.29127313245572 8.91724406714589e-16 -98.5408995721337 50.0270241741049 -1.96975337228115 0.0493763434411125 B4GALT4 other 7.01797729479784e-13 1 1.15585317598345e-11 8.29127313245572 -1.96975337228115 5.47043622545982e-24 977.347265344155 96.5623300127999 10.1214134457464 3.58729826902863e-22 -737.61164130546 321.844932330571 -2.29182307132881 0.0222984007181769 NAA50 essential 6.95894192240744e-20 1 5.02723979421672e-18 10.1214134457464 -2.29182307132881 0.000231212479127046 6.36996530132927 2.09295598696269 3.04352568377389 0.00245165564934287 21.5220664913481 6.65303429438613 3.23492492884165 0.00129092694024061 CD80 other 1 1 1 3.04352568377389 3.23492492884165 3.68111215631775e-05 59.7322003503569 13.3246409652246 4.48283751181359 9.0131605782641e-06 22.6332083397952 32.7482738567569 0.691126757971864 0.489785093540176 KIF18A essential 0.211663948988271 1 0.0815240374303988 4.48283751181359 0.691126757971864 1.47544562995113e-12 257.444348896761 34.4169402326146 7.48016375531251 3.00442517311531e-13 330.640506344762 215.86565236071 1.53169576877504 0.126179896069 DESI2 other 1.38529590196111e-08 1 3.70085092824344e-09 7.48016375531251 1.53169576877504 0.00104103076122373 68.4741326603215 24.4169444390142 2.80436943415866 0.00522861863737003 -98.6726852510679 69.9348672137951 -1.41092260816653 0.158860842292549 MAPK8IP1 other 1 1 1 2.80436943415866 -1.41092260816653 6.36688705061577e-08 -14.9969852770231 38.2431322083625 -0.392148456755949 0.695103822950063 -623.467443603893 110.560798297018 -5.63913659459087 2.76336768880643e-08 CRY2 other 0.000467584184997222 0.000372557231804883 1 -0.392148456755949 -5.63913659459087 2.99510658739705e-08 68.8652971682869 21.0405844111204 3.27297454399082 0.00113454397959953 -219.394947078357 59.7438827276074 -3.6722579293792 0.000265143824936031 PEX16 other 0.000225142162174636 1 1 3.27297454399082 -3.6722579293792 0.000105745444555386 8.27492727634256 1.99743579671658 4.14277509692428 3.98318490590033e-05 -3.49199317228724 8.89302110049919 -0.392666691422921 0.694720912236847 DEPDC7 other 0.572505836822858 1 0.341438610133777 4.14277509692428 -0.392666691422921 0.00229430356972319 250.170049392612 91.8439985882352 2.7238584255701 0.00666411537766078 -424.227918159462 282.229588612352 -1.50313055496866 0.133397628956982 CAT other 1 1 1 2.7238584255701 -1.50313055496866 6.67426599545751e-24 293.636147539807 66.5317491483324 4.41347403756281 1.23846526406564e-05 -869.283225858099 133.07521524278 -6.53226992172957 1.55006314360162e-10 ZMYM2 other 8.47898752062922e-20 2.20728991648871e-06 0.11074356391275 4.41347403756281 -6.53226992172957 1.06195618442556e-06 139.539254275029 26.277531521125 5.31021165983 1.62304669046148e-07 123.973987004204 51.8729527925524 2.38995430817279 0.0172041887412089 GJB6 other 0.00706838036353655 1 0.00163700489199945 5.31021165983 2.38995430817279 4.59082017458081e-27 211.826708151888 20.3509464550254 10.4086907515587 3.27325022421613e-23 -277.96979710807 78.4171481534032 -3.54475779410255 0.000427731201144745 TBC1D15 other 6.09660919184332e-23 1 4.63164906726583e-19 10.4086907515587 -3.54475779410255 0.00228285592130239 -28.0888786422881 120.813176812637 -0.232498468986125 0.816240122924502 -734.762079432814 224.61514824607 -3.27120448095454 0.00114017509820165 ADGRB2 other 1 1 1 -0.232498468986125 -3.27120448095454 5.15838892119086e-20 1.34055422649075 0.492592406803862 2.72142689975432 0.00671224794039536 -6.55684967049097 0.886579919829098 -7.39566679082345 5.48241727554367e-13 HCRTR1 other 6.11269087161117e-16 8.07614888860338e-09 1 2.72142689975432 -7.39566679082345 6.73635307155841e-15 157.220178593061 28.8072556118896 5.45765902560226 7.37392842721138e-08 -164.526427066602 50.0905212541624 -3.28458205159785 0.00108779600347202 ZCCHC17 other 6.93103367532645e-11 1 0.000759367149434228 5.45765902560226 -3.28458205159785 0.693176400804723 -105.138202162579 183.919008083225 -0.571654899938362 0.567794985898507 -264.418483098505 321.095082318495 -0.823489669132421 0.410595151911888 FABP3 other 1 1 1 -0.571654899938362 -0.823489669132421 3.15225152802924e-10 482.317012333539 93.1117742968258 5.1799787510867 3.14613575167699e-07 -308.092694935581 172.992293161175 -1.78096196833771 0.0754848953202848 KHDRBS1 other 2.65224766015621e-06 1 0.00312442741499042 5.1799787510867 -1.78096196833771 2.1194761796307e-07 54.3449223339323 12.4828589981788 4.35356374223733 1.60479014950523e-05 -33.0387553803422 23.1918940392931 -1.42458202526995 0.154860014309861 TMEM39B other 0.00149698602567316 1 0.142104167738688 4.35356374223733 -1.42458202526995 0.0133956684280973 5.00071486707456 5.27872441422228 0.9473339531803 0.343889248458853 -19.5746044762266 9.84583759461609 -1.98810962379985 0.047300310883509 CCRL2 other 1 1 1 0.9473339531803 -1.98810962379985 0.394448440978586 -8.48280794078709 7.76830661951855 -1.0919764571951 0.275325047431828 2.7728503801171 14.4564143155888 0.191807616991653 0.847964214666475 CCR2 other 1 1 1 -1.0919764571951 0.191807616991653 0.000181595318959175 953.912142567793 268.115791595564 3.55783647390195 0.000407274148342408 -2477.57155444937 1145.78177274702 -2.16234156746042 0.0310360130222761 TNFSF10 other 0.953375424535669 1 1 3.55783647390195 -2.16234156746042 2.33097845197119e-24 187.070174165667 17.0343116776293 10.9819626237872 1.9845494341523e-25 15.4939134405435 70.3699757793354 0.220177899295134 0.825817071539478 ZNF639 other 2.98365241852312e-20 1 2.84882071272563e-21 10.9819626237872 0.220177899295134 0.673769130013121 -5.77589614992357 7.28594610355572 -0.792744836131136 0.428277898976409 -12.0426195253719 28.4098766174564 -0.423888483837072 0.6718175187783 SLITRK3 other 1 1 1 -0.792744836131136 -0.423888483837072 3.35039356948755e-09 143.834953287844 22.7862305724207 6.31236275919787 5.79757717979231e-10 -85.5507893710865 94.1315694950788 -0.908842695707514 0.363844697922495 PIK3CA og 2.66724832066904e-05 1 6.51473747693262e-06 6.31236275919787 -0.908842695707514 5.26857432987052e-17 636.991997450965 107.497887959319 5.92562337310313 5.51358834717036e-09 -628.009094555151 219.608474396594 -2.8596760497549 0.00440292596093736 PDS5A other 5.78752890136276e-13 1 5.96294579746475e-05 5.92562337310313 -2.8596760497549 0.309943289497476 -12.8213185000736 16.1463991529848 -0.794066737641835 0.427500298283292 -49.0482430382922 32.0152928645272 -1.53202543690105 0.126093222195856 TMEM156 other 1 1 1 -0.794066737641835 -1.53202543690105 2.68111713081476e-40 25.9472349215682 5.85161624686058 4.43419968551237 1.11741770574258e-05 -117.836305149232 11.8416559194761 -9.95099891016301 1.48786956140193e-21 LIAS other 3.93185827233985e-36 2.30173421148878e-17 0.100310587444511 4.43419968551237 -9.95099891016301 0.903361016796488 -25.6560527056169 57.2833037544909 -0.447880115566929 0.654418682211258 -13.5347815019601 118.899738425482 -0.113833568359301 0.909411880743415 CPXM2 other 1 1 1 -0.447880115566929 -0.113833568359301 3.27103989288934e-08 439.408044818124 82.0516544568436 5.35526124033536 1.26602485276877e-07 -28.8953512297378 152.598647797197 -0.189355224616011 0.849885564899745 TMEM54 other 0.000245131729573127 1 0.00128476202058975 5.35526124033536 -0.189355224616011 2.26620987654121e-09 13.2036417918516 4.75162899292539 2.7787610967755 0.0056466599475127 -35.8553211281249 8.76389098411045 -4.09125594934181 4.94526606409683e-05 ZSCAN20 other 1.82271260370209e-05 0.570832061778697 1 2.7787610967755 -4.09125594934181 0.0815736921992104 10.6105087355637 10.6822827816183 0.99328101984174 0.321018717436071 -26.9066348155343 19.2435445927059 -1.39821614910451 0.162623217988553 CSMD2 other 1 1 1 0.99328101984174 -1.39821614910451 2.36309756549681e-08 60.4541018232029 12.0150785995274 5.03151946301716 6.63662295992001e-07 -21.1097822008645 22.3454939403966 -0.94469973486251 0.345234684294488 HPCA other 0.000178744699854179 1 0.00645544315311419 5.03151946301716 -0.94469973486251 0.000336614762841042 56.1475364262666 24.2014768613686 2.32000454963522 0.0207104565820201 -105.307886513098 51.9660436157928 -2.02647496683958 0.0432043889069476 LRIF1 other 1 1 1 2.32000454963522 -2.02647496683958 0.00895082256873993 5.82940565996623 4.2395757488632 1.37499740664601 0.169696198148266 -18.4597543543749 9.55166676536753 -1.93262126996582 0.0537997183101799 TMIGD3 other 1 1 1 1.37499740664601 -1.93262126996582 1.2614113554977e-40 341.236609984395 27.6616016814483 12.3361117665595 5.60926731151139e-31 -173.957650333184 65.2510627543435 -2.66597420777801 0.00790653376210405 CLCC1 other 1.85200415214172e-36 1 8.27703484486621e-27 12.3361117665595 -2.66597420777801 1.73760435476943e-22 474.513802184896 47.7844043889201 9.93030693283943 1.85953481656558e-21 88.0524049314493 112.718822480604 0.781168601602457 0.435045666363754 GPSM2 other 2.16018973384936e-18 1 2.59033199947585e-17 9.93030693283943 0.781168601602457 1.84261779818349e-05 44.9848063129625 13.8289410440255 3.25294656834171 0.00121475802178258 -68.3205916134548 32.2061809863284 -2.12135029739965 0.0343549646594944 GTDC1 other 0.109414644856135 1 1 3.25294656834171 -2.12135029739965 0.117822167421927 309.310579514149 154.970382092012 1.99593351541521 0.0464410712625165 50.1717526347615 353.757032424037 0.141825456559751 0.887270576333268 CXCR4 other 1 1 1 1.99593351541521 0.141825456559751 5.31530356042487e-11 27.7803643427687 6.18005367393304 4.49516554523531 8.50556538438587e-06 -51.297717282219 14.1574439546102 -3.62337420841524 0.000318146596648565 ZRANB3 other 4.64823296359155e-07 1 0.0770859390786891 4.49516554523531 -3.62337420841524 7.04604243130309e-05 22.9544777168208 14.4628178362283 1.5871373045522 0.113081328801472 -113.805738343065 33.804947083096 -3.3665409403931 0.000816725487441993 ACVR2A other 0.390703052815756 1 1 1.5871373045522 -3.3665409403931 1.76116015419047e-23 36.1921124235407 17.5741524471461 2.05939447335442 0.0399309221129369 -339.951757760974 38.6971287605594 -8.78493492022221 2.03321345501981e-17 POLK other 2.22328857865005e-19 3.10105716159621e-13 1 2.05939447335442 -8.78493492022221 1.70585241176892e-08 138.616069734992 25.5775991168019 5.41943241435571 9.10493539310145e-08 2.87054773302423 54.1265193171879 0.0530340352425486 0.957724848534967 FLT3 og 0.000130173597542086 1 0.000932709581669312 5.41943241435571 0.0530340352425486 1.06442941148262e-15 97.2980360966342 19.2861665780767 5.04496503764706 6.23092025290735e-07 -159.090713967192 41.6090076283524 -3.82346811508158 0.000147134523759792 RPL21 other 1.12456967323139e-11 1 0.00606953941835705 5.04496503764706 -3.82346811508158 5.22833856850338e-47 206.028834518023 19.6232942359321 10.4991971297442 1.45835335456151e-23 -257.794415209571 42.3315265918127 -6.08989176543024 2.1667077638643e-09 MTIF3 other 7.84564485589617e-43 3.01259047487693e-05 2.06896590411642e-19 10.4991971297442 -6.08989176543024 2.90912539235921e-50 1042.14922499804 73.4024198957103 14.1977502441843 4.90958346490241e-39 -241.732950876036 158.362307875737 -1.52645508971565 0.127489727297426 GTF3A essential 4.40267036879643e-46 1 7.40757953184476e-35 14.1977502441843 -1.52645508971565 3.33726788308791e-07 22.6286949521219 8.89558609561201 2.54381158350928 0.011246242391134 -61.1801809937805 19.1918133763157 -3.18782700697173 0.00151757495820499 RASL11A other 0.00232140353947595 1 1 2.54381158350928 -3.18782700697173 6.98032371617253e-23 282.143079798498 55.6640045813846 5.06868095316401 5.55383114663433e-07 -713.601061846469 120.982372340552 -5.89838873251517 6.56711297493987e-09 UBL3 other 8.72959283944536e-19 9.02386993886488e-05 0.00542886994583505 5.06868095316401 -5.89838873251517 2.25244678530185e-38 519.074632173563 36.3198933707099 14.2917443857963 2.19487280002307e-39 -174.905040692168 157.037094533572 -1.1137816909544 0.265881538668305 FYTTD1 other 3.27483238115036e-34 1 3.31359946619482e-35 14.2917443857963 -1.1137816909544 1.0386288771936e-23 30.9971082556019 22.1002797820841 1.4025663277227 0.161314521575436 -408.408495258501 42.941886225868 -9.5107255678135 5.98920169177872e-20 MTERF4 other 1.31625437606744e-19 9.22337060533923e-16 1 1.4025663277227 -9.5107255678135 0.439511042086367 -7.94405523596648 6.90935053576344 -1.14975426342133 0.250755934604522 -15.3039527458105 16.362146425082 -0.93532671987036 0.350039576463119 PAEP other 1 1 1 -1.14975426342133 -0.93532671987036 0.556795410442481 -12.0359119050593 12.8663636910814 -0.93545559522791 0.349973245670809 5.62120934120635 30.4690470663132 0.184489174504614 0.853699238923734 OBP2A other 1 1 1 -0.93545559522791 0.184489174504614 2.04360506811282e-08 197.683089598031 35.8261957863148 5.51783646740256 5.3455069967438e-08 -35.7860658163186 84.9823087438892 -0.421100183617826 0.673850413849671 MRPS2 other 0.000155273113075212 1 0.0005543825306323 5.51783646740256 -0.421100183617826 0.031185525236361 383.439454429289 188.965272483986 2.02915302578564 0.042931800742056 -2726.72340700738 1573.48802845386 -1.73291652538768 0.0836803464805472 FMOD other 1 1 1 2.02915302578564 -1.73291652538768 0.116495821371603 1.32402350683319 2.19095762903174 0.604312693814312 0.545890046170221 36.2251069837664 18.4281434328551 1.96574913342499 0.0498405179971734 LAX1 other 1 1 1 0.604312693814312 1.96574913342499 4.48493757616032e-26 304.545270573729 45.6972144023538 6.66441651984027 6.54897836672793e-11 -807.467376337244 127.654053284627 -6.32543468507698 5.28846509057971e-10 KIAA1191 other 5.88468659367995e-22 7.4540915451721e-06 7.58109735732425e-07 6.66441651984027 -6.32543468507698 7.92774116922715e-24 1664.52559139153 155.111687978922 10.7311422696768 1.7473349159265e-24 -2369.91314900138 1495.35948868333 -1.58484509372933 0.113586946441991 COPA essential 1.00618890919831e-19 1 2.49467005946827e-20 10.7311422696768 -1.58484509372933 0.983575501899337 0.115313933565467 0.633924061642488 0.181904963926894 0.855725571052276 0.0175827668158985 6.53137778750391 0.00269204559710793 0.997853055165778 CD244 other 1 1 1 0.181904963926894 0.00269204559710793 0.16179859243968 -3.47547278873965 1.90367120583799 -1.82566862285956 0.0684523226973095 -10.5224269514914 19.6136991492416 -0.536483550166941 0.591845339022518 LY9 other 1 1 1 -1.82566862285956 -0.536483550166941 0.885524822987624 -0.0847488419393379 3.1709866013327 -0.0267263323987934 0.978687865865607 -8.46512727568272 17.5132092727694 -0.48335671342915 0.629038038302593 HS3ST2 other 1 1 1 -0.0267263323987934 -0.48335671342915 9.75271148231504e-09 139.442666968913 25.9260777254176 5.37847137718812 1.11890447153034e-07 -235.439645516836 144.318777536645 -1.63138608527261 0.103389752280307 RBBP6 essential 7.54469760271891e-05 1 0.00113904475201788 5.37847137718812 -1.63138608527261 8.39489313326116e-13 105.633320234003 19.7018555535111 5.36159246255248 1.22547251523937e-07 -370.879847518365 102.300444388891 -3.62539820558825 0.000315879929363338 ZC3H7A other 7.95080328651165e-09 1 0.00124471243372863 5.36159246255248 -3.62539820558825 1.17781068391237e-20 46.7308857124033 8.27260546566596 5.64887155641011 2.60622914535363e-08 -77.8356738415964 17.5613431630261 -4.4322164380611 1.12853934403208e-05 SERAC1 other 1.41243057214772e-16 0.135810992224866 0.000274435929005737 5.64887155641011 -4.4322164380611 5.54358733827861e-27 673.582203980016 67.9080857487284 9.91902800017638 2.00516315210569e-21 -1033.72187735917 249.811294463155 -4.13801097176426 4.05980998121122e-05 ANXA11 other 7.35356860422657e-23 0.470856761620877 2.79239020562238e-17 9.91902800017638 -4.13801097176426 0.705967937609747 183.800869633541 284.247628174115 0.646622351131651 0.518151632100655 -177.528311593227 621.196296046556 -0.285784562340536 0.775152927948889 LDB3 other 1 1 1 0.646622351131651 -0.285784562340536 2.86054629110628e-20 152.758506164583 26.640976838651 5.73396790552212 1.64163280296738e-08 -326.526801140447 56.6545032363318 -5.7634747899625 1.39287509451193e-08 FAM35A other 3.40519430493291e-16 0.000189653872868744 0.000174193656722869 5.73396790552212 -5.7634747899625 5.17119928147902e-41 1122.02003954726 77.2084231144545 14.5323527445182 1.17748937004416e-40 -116.134297105607 283.740214473949 -0.409297981679892 0.682482392770427 FAM213A other 7.60579990319934e-37 1 1.78165916581382e-36 14.5323527445182 -0.409297981679892 1.34170334839268e-11 75.8165948278123 12.3127845410868 6.15755068033705 1.43625239232134e-09 -95.9253513991401 57.8538492023975 -1.65806342571178 0.097881135173884 ZNF205 other 1.20793552455793e-07 1 1.58806427018971e-05 6.15755068033705 -1.65806342571178 3.16969874548364e-30 247.466290870871 26.0445981888506 9.50163596598731 6.56706901581739e-20 -537.910827658925 120.186174263069 -4.47564647894957 9.28709173233348e-06 NAA60 other 4.34502304030897e-26 0.11235523577777 9.02183941392993e-16 9.50163596598731 -4.47564647894957 2.51310975956047e-14 1141.84588588121 465.048384348763 2.45532706769901 0.0143897819655652 -5425.82464931962 889.556804102704 -6.09946956090415 2.02985282539833e-09 RPL5 other 2.5289423510457e-10 2.82413423597669e-05 1 2.45532706769901 -6.09946956090415 8.89004551084945e-12 226.179087144943 37.0483628849133 6.10496846642169 1.9566057711578e-09 -87.035455729807 71.6701454647349 -1.21438927136868 0.225125998053512 ODF2L other 8.07927336025998e-08 1 2.15167936654223e-05 6.10496846642169 -1.21438927136868 0.0259666716740932 44.5936695240026 16.487495932487 2.70469631693041 0.00705246835069021 41.1609276798597 33.2478481914259 1.2380027556332 0.21625300712727 PTGFR other 1 1 1 2.70469631693041 1.2380027556332 3.72242513079405e-10 33.2189159800179 9.89829729067545 3.35602326385077 0.000846659876027576 -75.4948459466185 18.9094648526839 -3.99243693752143 7.44999396818484e-05 TRMT13 other 3.11939225960542e-06 0.847809313579434 1 3.35602326385077 -3.99243693752143 0.581407777671892 -3.78844725244761 21.3537712389157 -0.177413498068361 0.859250503540958 -41.2711823399654 40.7937218752676 -1.01170426337067 0.312135102360811 LRRC39 other 1 1 1 -0.177413498068361 -1.01170426337067 8.9056433169444e-21 50.0801559387198 7.95944591232365 6.29191485065317 6.47041260071096e-10 -70.4064942247899 15.7700571544632 -4.46456810746965 9.76624398854642e-06 RWDD3 other 1.07179417319426e-16 0.117985993625629 7.25268548413692e-06 6.29191485065317 -4.46456810746965 1.96525029968968e-14 321.126677319125 47.5135908216086 6.75862783187248 3.63832863675029e-11 -147.119161511365 93.2764023681065 -1.57723880613205 0.115329464334007 ZNF644 other 1.98509932771654e-10 1 4.24447418763289e-07 6.75862783187248 -1.57723880613205 8.37906028062471e-12 50.5621813341327 8.62994612520887 5.85892201417526 8.13867267775418e-09 -27.0019420839032 16.4324447127567 -1.64320906328328 0.100926121472912 CCDC18 other 7.62494485536848e-08 1 8.73849285410466e-05 5.85892201417526 -1.64320906328328 2.80014488892276e-12 114.292221959016 24.1317411673619 4.73617801410848 2.78971233545869e-06 -156.011782689536 45.9479738253292 -3.39540070434038 0.000735873244152216 RPAP2 other 2.60189463078703e-08 1 0.0261172868845643 4.73617801410848 -3.39540070434038 4.84389633363941e-10 136.032663530692 37.2737645841236 3.64955525819451 0.000289544310179984 -262.470527977939 76.7284046144585 -3.42077395322879 0.000674129180224642 PQLC1 other 4.03738759408845e-06 1 1 3.64955525819451 -3.42077395322879 1.47758645799046e-10 31.4320634010269 6.80450354351408 4.61930296604626 4.8113838276723e-06 -112.63024167012 27.8027310330897 -4.05104957265068 5.84100309586909e-05 BBS9 other 1.26481400803984e-06 0.67019669522002 0.0443224678205172 4.61930296604626 -4.05104957265068 0.000111096051042548 296.870503602366 73.1189307695422 4.06010455128301 5.63675143264717e-05 -167.432140535924 287.688018995127 -0.581992052087368 0.560816734171673 ZMIZ2 other 0.600029771680803 1 0.476869171201951 4.06010455128301 -0.581992052087368 2.47766040242954e-10 292.353345474893 54.9858037869851 5.31688772992152 1.54456575605023e-07 -574.719884415012 210.305892990829 -2.73278069502348 0.00648485630824434 SEPT7 other 2.09857836085782e-06 1 0.0015589302175815 5.31688772992152 -2.73278069502348 0.163016632821175 14.7645981276193 11.5162962410726 1.2820613345254 0.200368229446956 -45.8531201951445 44.0467320312038 -1.04101071931196 0.298333852709467 EEPD1 other 1 1 1 1.2820613345254 -1.04101071931196 2.20865645905651e-10 114.921237673974 17.2589030257321 6.65866408210492 6.84444114798992e-11 13.0983996057977 77.9927831334436 0.167943738889106 0.866690769853454 KLHL7 other 1.87691625890622e-06 1 7.91901840822433e-07 6.65866408210492 0.167943738889106 3.63039943230787e-21 76.5686040927767 11.1946278277529 6.83976325706457 2.13636890762814e-11 -237.002751532827 43.0838806881075 -5.50096109606597 5.81694562763613e-08 HERPUD2 other 4.40149627173006e-17 0.000775806038357831 2.51044710335383e-07 6.83976325706457 -5.50096109606597 8.55637421655936e-58 1856.03206222331 101.491181497177 18.2876190309692 1.75540451797786e-58 399.416331550481 519.33015424002 0.769099056331479 0.442171387393332 CBX3 other 1.31117878494556e-53 1 2.71034457575782e-54 18.2876190309692 0.769099056331479 9.47684812780439e-11 1459.3332875197 210.915276005358 6.91904974906905 1.29908348918035e-11 525.63169917715 1088.25374417379 0.483004723844266 0.629289234711815 HNRNPA2B1 og 8.17946761910797e-07 1 1.53629613430468e-07 6.91904974906905 0.483004723844266 0.0932719572123245 -1.64299709514572 10.7714501466188 -0.152532581294215 0.878824081494811 94.9779456955109 45.1998668384912 2.10128817491625 0.0360802107113308 WIPF3 other 1 1 1 -0.152532581294215 2.10128817491625 0.564313580605766 -1.1818366371953 27.5177353723686 -0.0429481794632714 0.965758572479231 -103.267045022901 98.7959772731109 -1.04525556478307 0.296368243838435 NXPH1 other 1 1 1 -0.0429481794632714 -1.04525556478307 0.926264258710568 -1.41793558516651 5.20964850119055 -0.272174904860179 0.785592152433304 -9.26631898933796 28.2552743892123 -0.327950062055521 0.743077245022536 NPY other 1 1 1 -0.272174904860179 -0.327950062055521 0.104594875539896 14.1732611683394 19.8827057369155 0.712843682136503 0.476250403898702 187.080213843915 88.2508790900978 2.11986799194283 0.034472675915074 FAM126A other 1 1 1 0.712843682136503 2.11986799194283 0.383327760287149 -22.7523018608862 18.0620097459538 -1.25967719987435 0.208347670331288 26.3806644469616 75.5623360598272 0.349124521852719 0.727136343752506 HOXA7 other 1 1 1 -1.25967719987435 0.349124521852719 0.975733856332891 18.1630219810601 89.9957702376989 0.201820840391581 0.84013168427815 -15.1989598502532 350.568015963897 -0.0433552382366179 0.965434151271484 INHBA other 1 1 1 0.201820840391581 -0.0433552382366179 7.32414291594103e-08 450.837019329084 82.6296980882149 5.4561135978952 7.39598431903944e-08 -289.324757923171 347.819130108394 -0.831825316315999 0.40587186463201 FKBP9 other 0.000534880998377748 1 0.000761564505331491 5.4561135978952 -0.831825316315999 1.72876576831665e-06 76.9979233892486 15.3347378630732 5.02114376370682 6.96930923909829e-07 -20.8134857900296 64.5636216050954 -0.322371720677871 0.747294729749692 NT5C3A other 0.0113009418274859 1 0.00677207778763181 5.02114376370682 -0.322371720677871 0.0398670264330304 -20.1351749889554 24.5941019671118 -0.818699337584311 0.413318449009831 -221.955154638651 87.4255850660633 -2.53878946844828 0.0114027478406582 ARL4A other 1 1 1 -0.818699337584311 -2.53878946844828 4.45614504683803e-20 226.9698675347 23.7363032457799 9.56214053993658 3.96233066360478e-20 14.3108639631085 83.0506659574283 0.172314861032472 0.863254087462445 CCZ1 other 5.28454241104521e-16 1 5.45692178991651e-16 9.56214053993658 0.172314861032472 0.361650224599947 -52.4027283490238 153.867289068709 -0.340570946990712 0.733558566964297 -869.813505806199 609.754487227285 -1.42649791682792 0.154300422832794 RAMP3 other 1 1 1 -0.340570946990712 -1.42649791682792 3.28129205617268e-19 108.389059526586 14.4890332879889 7.48076544322927 3.07407004278348e-13 -190.332507246822 49.2939178975286 -3.8611762944565 0.000126728647293221 MRM2 other 3.81548640291759e-15 1 3.78571725768786e-09 7.48076544322927 -3.8611762944565 0.761116165510116 10.5359488901411 29.7706516351039 0.35390387215165 0.723548807186078 -69.6285824978288 127.032957841738 -0.548114313645868 0.583839498557347 TWIST1 other 1 1 1 0.35390387215165 -0.548114313645868 1.21410692968814e-59 338.7894236632 28.0325249612313 12.0855835901954 6.18063251463641e-30 -611.916486413767 68.0186202043328 -8.99630843106675 3.93428753899111e-18 SMU1 essential 1.8640183691502e-55 6.0186730771486e-14 9.08182141700674e-26 12.0855835901954 -8.99630843106675 1.77611450289518e-10 335.105860342372 49.0601433509958 6.83051123485089 2.30707818928448e-11 210.216425365799 128.569737743136 1.63503814393541 0.102629247285612 GLIPR2 other 1.51591372822104e-06 1 2.70781767076319e-07 6.83051123485089 1.63503814393541 1.65197010410924e-14 47.2764372795479 6.99763550615407 6.7560588484454 3.70451922285043e-11 -41.8031604911886 17.4528021157724 -2.39521196733276 0.0169529451397547 SLC25A51 other 1.67377610948348e-10 1 4.31983986576589e-07 6.7560588484454 -2.39521196733276 3.0506343991041e-20 523.018159376515 64.2099612528609 8.1454364583223 2.68136016390578e-15 -482.663213629147 167.871805330335 -2.87518927123808 0.00419864924461201 CLTA other 3.62964480805406e-16 1 3.44554781061892e-11 8.1454364583223 -2.87518927123808 0.523156342162943 -14.1046824938624 18.3271576348214 -0.769605564316403 0.441872924051277 -49.699743171988 48.0966833780206 -1.0333299446319 0.301915518822275 RECK other 1 1 1 -0.769605564316403 -1.0333299446319 0.922942367570488 2.51103122860348 6.79379122981919 0.369606769425312 0.711821213174646 4.60774372891482 16.3616782439181 0.281618038212406 0.778344895552493 TAF1L other 1 1 1 0.369606769425312 0.281618038212406 0.049669765181431 101.211173644086 73.2230663042419 1.3822307471194 0.167475495472233 -239.512540255387 174.677377092094 -1.37117092231761 0.17089440291424 ACO1 other 1 1 1 1.3822307471194 -1.37117092231761 0.236616488814985 7.66144633721736 5.26138279106123 1.4561659247135 0.14592898665266 18.0309832374177 14.103493166001 1.2784764047594 0.201631725143183 PHF24 other 1 1 1 1.4561659247135 1.2784764047594 0.00631481584812061 6.48878367301516 4.24115328837985 1.52995735636188 0.126616118218895 -24.774276786237 11.3336871551688 -2.18589735600198 0.0292542149928753 DNAI1 other 1 1 1 1.52995735636188 -2.18589735600198 1.37586838161843e-06 298.662328714682 166.691234833116 1.79170985813195 0.0737444844261036 -1733.79441933069 415.775842777517 -4.17002201895229 3.55273350209617e-05 DCAF10 other 0.00907797958191842 0.413502652308973 1 1.79170985813195 -4.17002201895229 2.83899281528071e-05 75.9685118450842 17.4598517692754 4.35103990852707 1.62273563989832e-05 -5.53414214101658 46.5629741230791 -0.118852849184167 0.905436467187049 CNTFR other 0.165059042280421 1 0.143677013556598 4.35103990852707 -0.118852849184167 4.67100930669925e-07 108.752530652921 28.2687209311315 3.84709767795526 0.000133610131878754 -199.292904619818 83.5588339825533 -2.38506086216365 0.0174158612316358 KIAA1549 other 0.00320637658583854 1 1 3.84709767795526 -2.38506086216365 1.81211288132377e-15 151.111896522788 34.8063338624004 4.34150569031996 1.68686006746795e-05 -560.225006460001 103.454064510433 -5.41520537748909 9.18751655275835e-08 TRIM24 other 1.89891308833918e-11 0.00121762156873706 0.149118429964167 4.34150569031996 -5.41520537748909 1.72653238925239e-24 119.194283145234 13.8707713992643 8.59319786292178 8.88002262765068e-17 -166.558868453376 45.1603192538981 -3.68816853390599 0.00024843112530007 C7orf49 other 2.21427778921619e-20 1 1.17198538639734e-12 8.59319786292178 -3.68816853390599 0.49944763821169 225.061058376218 265.041117561522 0.849155257293148 0.396167056878035 898.990067482729 855.10653895405 1.0513193696102 0.293577003924732 CALD1 other 1 1 1 0.849155257293148 1.0513193696102 0.25046582101379 200.555600382926 124.963040969895 1.60491933315901 0.109107220340829 21.8461072172812 320.656731375361 0.0681292643493835 0.94570842926965 PLAU other 1 1 1 1.60491933315901 0.0681292643493835 0.0279731945474029 104.021606006441 60.1114315030715 1.73047960105767 0.084111715035149 404.046348347504 162.906741456203 2.48023098820703 0.0134311896402071 SRGN other 1 1 1 1.73047960105767 2.48023098820703 0.00846573796943933 91.0666415552241 47.011255833634 1.93712420441385 0.0532503863779176 353.743438768812 121.691339955096 2.90689081819086 0.0038000619464203 CHST3 other 1 1 1 1.93712420441385 2.90689081819086 0.647678067278694 -11.0892262151137 23.438173169028 -0.473126729423069 0.636317930865895 -55.0681148063995 60.5236392548774 -0.909861262216841 0.363310046392376 BICC1 other 1 1 1 -0.473126729423069 -0.909861262216841 7.82817369805298e-08 69.0366979468512 12.6720497246883 5.44795036688901 7.80731814041457e-08 -10.2282197289237 34.3208088495522 -0.298018026724251 0.765805975011117 CISD1 other 0.00057028245390316 1 0.000802904597560235 5.44795036688901 -0.298018026724251 0.490747686695993 -54.5181791820846 52.1811139117518 -1.04478756958476 0.296595651672885 -118.003824960585 132.856238633359 -0.888206878159763 0.374830876940336 EGR2 other 1 1 1 -1.04478756958476 -0.888206878159763 2.28969320855043e-29 171.940647985632 20.3037569211691 8.46841540968035 2.37179125063838e-16 -289.996782114736 52.06207435843 -5.57021182287524 4.0211169617892e-08 ECD essential 3.11466967159115e-25 0.000539151362236696 3.10609782183602e-12 8.46841540968035 -5.57021182287524 1.32727229679422e-14 778.805987520829 95.9192161370397 8.11939482916697 3.2356210333805e-15 328.132144565309 245.911301402693 1.33435162472657 0.182655237054885 P4HA1 other 1.34943774415068e-10 1 4.1522724721372e-11 8.11939482916697 1.33435162472657 3.11320569862e-10 130.682516037396 26.761041978939 4.88331194802665 1.37549286403153e-06 -207.794368596994 69.7690628688126 -2.97831675032975 0.00302833347954559 SLC25A16 other 2.62131919823804e-06 1 0.0131290793871809 4.88331194802665 -2.97831675032975 1.88858370913139e-09 309.532047779415 48.9354775075954 6.32530964332312 5.37027139971793e-10 91.7127085370276 131.889843572799 0.69537354850531 0.487125426167575 ZWINT essential 1.52616449534907e-05 1 6.03940721612279e-06 6.32530964332312 0.69537354850531 3.63666716906643e-31 379.505797940923 35.096783540108 10.8131218778846 8.0946381418151e-25 -279.324111498297 94.752092352179 -2.94794663172283 0.00333626402558475 VPS26A other 5.03205636183722e-27 1 1.15793798618665e-20 10.8131218778846 -2.94794663172283 2.71242191424725e-18 63.2037159978726 15.242334884313 4.14659016991682 3.91626620036869e-05 -225.553186713391 33.9107807614321 -6.65137108756637 7.10877135476507e-11 RBM19 essential 3.08348123211627e-14 1.01854475971074e-06 0.33597647732963 4.14659016991682 -6.65137108756637 5.2553042046717e-12 45.0777567130191 13.8918666467196 3.24490278084147 0.00124778457820219 -166.227957310039 31.2504822644228 -5.31921254537829 1.53010838068658e-07 IFT81 other 4.82857350325236e-08 0.00200872628216534 1 3.24490278084147 -5.31921254537829 0.00137435520183856 19.7193601605134 32.592648112824 0.605024792470133 0.545415276675696 -235.812141703094 72.5185316376805 -3.25175008894646 0.00121814386829335 ACADS other 1 1 1 0.605024792470133 -3.25175008894646 0.0679081913235324 -5.96533202285987 4.91349719626702 -1.21407050509604 0.225251490588876 -24.8148710088695 10.9593581465098 -2.26426316916856 0.023953669294418 HVCN1 other 1 1 1 -1.21407050509604 -2.26426316916856 7.01398576482538e-14 252.746382013313 49.538250987353 5.10204492439264 4.65499824014711e-07 -476.101823542093 109.957853603596 -4.32985737661328 1.77768905918324e-05 DDX54 essential 6.94314450860064e-10 0.211367229136887 0.00457586327006461 5.10204492439264 -4.32985737661328 9.89634835208092e-11 223.121836005802 224.814178866497 0.992472259226587 0.321410887309429 -3059.4629318475 493.240329896412 -6.20278340274818 1.10291336858578e-09 MED13L other 8.53065227949375e-07 1.54363755067266e-05 1 0.992472259226587 -6.20278340274818 4.54933752118745e-06 216.741295791095 48.7922762469507 4.4421230666532 1.08179858330148e-05 -65.4168795391849 98.3788970979933 -0.664948291441248 0.506368496203359 CDKN2C other 0.0285197969203241 1 0.0972104206954708 4.4421230666532 -0.664948291441248 3.07931670507577e-11 210.958782675534 77.7346853923773 2.71383079008668 0.0068643120784637 -821.146854291775 157.328769111642 -5.21930514634029 2.56894114080763e-07 RNF11 other 2.72581114733307e-07 0.00334013727127809 1 2.71383079008668 -5.21930514634029 0.0141596584968812 56.2994364225999 30.7444488122749 1.83120656240622 0.0676277502706053 -236.51320605662 127.59514607713 -1.8536222836694 0.0643455497909025 RASSF8 other 1 1 1 1.83120656240622 -1.8536222836694 2.00203491565197e-08 267.050802744023 46.3879268982184 5.75690315564155 1.44760804770269e-08 -219.111994883403 251.786016655824 -0.870230991353721 0.384565928292319 BHLHE41 other 0.000152194694287863 1 0.00015405444843652 5.75690315564155 -0.870230991353721 1.07780700123391e-09 168.778663995599 27.4079119742038 6.15802707460724 1.45113010794323e-09 -173.193857269868 148.781683456537 -1.16408050538333 0.244912187954722 SSPN other 8.8067610070823e-06 1 1.60407922132045e-05 6.15802707460724 -1.16408050538333 0.0109432385334202 262.377789453598 123.511805860237 2.12431344215384 0.0341019194519404 -1161.71860350714 673.247850364901 -1.72554372491125 0.0850069606333349 ITPR2 other 1 1 1 2.12431344215384 -1.72554372491125 3.61457914666159e-16 114.299195954444 15.1191324053742 7.55990442373634 1.75135766962775e-13 -261.977128294234 86.311167237599 -3.03526341583423 0.00251952749999017 CCDC91 other 3.87374447147723e-12 1 2.16940674536789e-09 7.55990442373634 -3.03526341583423 0.752704052662475 9.4375717174898 12.6485152721641 0.74614067457066 0.455917679694932 -5.89223164106128 129.282452322103 -0.045576422284913 0.963665258536331 NECAB1 other 1 1 1 0.74614067457066 -0.045576422284913 1.06568103623315e-28 1433.41777017212 122.950962526514 11.6584509849852 4.53539930611298e-28 -4212.91181482027 1333.112496099 -3.16020727969188 0.00166819667236878 WWP1 other 1.44026792046911e-24 1 6.61034448865967e-24 11.6584509849852 -3.16020727969188 7.85540645501663e-38 612.502167440781 43.6251928220412 14.0401022395326 2.39047479923396e-38 293.589468794055 163.069894478664 1.80039037697709 0.0723621565580668 DDX39A other 1.13895538191286e-33 1 3.60029409512627e-34 14.0401022395326 1.80039037697709 4.22924260695995e-15 626.538170046946 88.1388476225188 7.10853598552009 3.7624391210665e-12 -774.264364541193 328.039901577475 -2.36027495685104 0.0186186500671087 PKN1 other 4.38064949228912e-11 1 4.5149269452798e-08 7.10853598552009 -2.36027495685104 1.13899939198478e-06 124.62288413594 23.6310521034775 5.273691733666 1.94287305343366e-07 82.2768872195245 90.337653317756 0.910770694143687 0.362825602910541 ADGRE5 other 0.00756067796399499 1 0.00195258741870083 5.273691733666 0.910770694143687 6.12731425731945e-24 135.520406751698 18.5181834693124 7.31823437089694 9.19685018950258e-13 -313.161917234915 56.2123276606471 -5.5710540777722 4.00606383836422e-08 WDR83 other 7.78904188390449e-20 0.000537213160724642 1.11787714053404e-08 7.31823437089694 -5.5710540777722 4.40988076600021e-19 575.496466014297 64.5526534683765 8.91514810148317 7.50094088689035e-18 -219.681589842008 241.009260031848 -0.911506843400864 0.362435100158148 GIPC1 other 5.11237477202404e-15 1 1.00692630465616e-13 8.91514810148317 -0.911506843400864 9.51343353246202e-46 61.8937516276135 6.97710373713308 8.87098056149096 1.06589367958105e-17 -83.6326642190587 12.8850322855416 -6.49068332664586 1.93994848244308e-10 SPRYD7 other 1.42368532813294e-41 2.75899473173055e-06 1.42691186885516e-13 8.87098056149096 -6.49068332664586 2.42625613070536e-31 182.426303407348 20.7272674808842 8.80127125177457 1.82963684240201e-17 -116.192687268376 38.3373684072628 -3.03079455099906 0.00255603170364874 EBPL other 3.36327624838377e-27 1 2.44018665671157e-13 8.80127125177457 -3.03079455099906 2.51003596911145e-11 -107.76793020101 57.319182542612 -1.88013724935615 0.0606355237938787 -684.232416790758 99.8066125607139 -6.85558200239016 1.97471918272912e-11 ATP7B other 2.23167298013699e-07 2.8548515224715e-07 1 -1.88013724935615 -6.85558200239016 2.8848954951506e-15 300.216218046486 79.6220684041576 3.77051518584777 0.000180817284743482 -696.506373849661 152.199682436942 -4.57626693234549 5.8738600255453e-06 ZC3H13 other 3.00461865819935e-11 0.0718901728526489 1 3.77051518584777 -4.57626693234549 0.000229281649603917 13.1497179764299 3.21067619106347 4.0956226021891 4.86207780595302e-05 9.88646464064745 5.90701132088559 1.67368303590203 0.0947774193126373 GUCY1B2 other 1 1 0.413227992727947 4.0956226021891 1.67368303590203 0.00346355063193931 81.5741912732817 33.7718460793907 2.41544957541017 0.0160468127403232 234.796665093067 74.2989512381918 3.160161229468 0.0016651811679042 NLN other 1 1 1 2.41544957541017 3.160161229468 0.0431703672526479 17.7974296520176 7.44950213410062 2.38907638814526 0.0172336915417463 28.1844504226459 16.4895445786335 1.70923158539903 0.0879836712530331 CENPK essential 1 1 1 2.38907638814526 1.70923158539903 1.37330716881545e-12 418.357352645947 55.4920870043161 7.53904520861519 2.00401562274189e-13 30.8345262327413 307.987393790557 0.100116195839204 0.920289097724065 OPTN other 1.29104606940341e-08 1 2.47896732533172e-09 7.53904520861519 0.100116195839204 0.826037249712609 -64.2647547700136 104.1291601601 -0.617163863332863 0.537386301685592 -26.53145244693 451.59809742634 -0.0587501422130271 0.953172814478191 ITIH5 other 1 1 1 -0.617163863332863 -0.0587501422130271 2.26942646023192e-07 41.8588294572163 11.0493774984126 3.7883427788787 0.000168604085611878 -96.0810915456777 32.4817255024612 -2.95800454130423 0.00323124901576497 ATF1 other 0.00159858399858736 1 1 3.7883427788787 -2.95800454130423 5.66123003072239e-13 144.211773854476 21.6979754011837 6.64632396286194 7.55416914115624e-11 -139.491408322562 62.424733781385 -2.23455351545541 0.0258675120504407 TSFM essential 5.3940199732723e-09 1 8.7318641102625e-07 6.64632396286194 -2.23455351545541 0.330895558064995 -12.9812454973839 8.85810290503947 -1.46546564614854 0.143401799427075 -2.62471648633721 25.3925033575239 -0.103365802472543 0.917712734998827 ARHGAP9 other 1 1 1 -1.46546564614854 -0.103365802472543 0.572611522066491 -24.7260125717091 33.2517767560597 -0.743599740642524 0.45744147083814 49.9046599387058 96.4735929083305 0.517288290342057 0.60516635428997 NCKAP1L other 1 1 1 -0.743599740642524 0.517288290342057 0.0298618024373108 -22.5580508045398 19.4260328365641 -1.16122787366449 0.246056654037423 -149.090559672 56.9681135000897 -2.61708788499316 0.00911414086521097 MMP19 other 1 1 1 -1.16122787366449 -2.61708788499316 4.18285816187349e-13 238.882445971732 135.153594780121 1.76748865881345 0.0777111393685601 -2638.50269373776 389.929454219775 -6.76661551258611 3.44053413422826e-11 PFDN5 other 4.00759640489099e-09 4.95540131352897e-07 1 1.76748865881345 -6.76661551258611 1.0326180846825e-10 141.596399099774 22.5403875567037 6.28189727188883 6.87129220057413e-10 -81.3708506449919 69.0327444399763 -1.17872831661421 0.239023582238893 SPATS2 other 8.89600479953975e-07 1 7.69653439386309e-06 6.28189727188883 -1.17872831661421 1.29367841623661e-31 248.10594636631 28.8164983107141 8.60985757849916 7.84525135323123e-17 -566.712778926756 84.5062684826727 -6.70616262085878 5.00053120209731e-11 ORMDL2 other 1.79704868799428e-27 7.18326307181279e-07 1.03643615627538e-12 8.60985757849916 -6.70616262085878 0.363139396722172 1.56294946849324 282.905622143087 0.00552463205451158 0.995594029110958 -1144.89742186148 838.419480352558 -1.36554248641748 0.17264696182784 NR4A1 other 1 1 1 0.00552463205451158 -1.36554248641748 0.764843835856111 -6.27837430138948 9.17656181414114 -0.684175013316477 0.494157618732729 1.92011734930082 26.8434932667813 0.0715300847850883 0.943002316476824 PDE1B other 1 1 1 -0.684175013316477 0.0715300847850883 0.000542790886464542 70.0841047855781 18.8985566923359 3.70843688893978 0.000230270328088724 -10.5166340552405 58.0925731328099 -0.181032333189951 0.85641062853409 HOXC13 other 1 1 1 3.70843688893978 -0.181032333189951 1.66105190486783e-09 181.095257021458 30.816619346019 5.87654521698378 7.34321113620417e-09 381.483824644309 90.5095763813192 4.21484488046997 2.93065737809859e-05 CDK2 essential 1.34511983256197e-05 0.343179978975345 7.90423246701017e-05 5.87654521698378 4.21484488046997 0.111022226627116 -486.530749012513 506.959362577303 -0.959703646736231 0.337652119981172 -3103.26753440126 1518.38339988003 -2.04379706380249 0.0414788590483637 LRP1 other 1 1 1 -0.959703646736231 -2.04379706380249 6.05762992829951e-07 87.4713172224098 16.4980815377273 5.30190840810084 1.6791790622911e-07 18.1525402083057 51.1064635640027 0.355190692965334 0.722586721303196 HOXC11 other 0.00412100564022216 1 0.0016924445768832 5.30190840810084 0.355190692965334 2.59728583079689e-07 172.752604555473 34.5221199556042 5.00411344313832 7.59293221848758e-07 -97.443475027754 102.91868538879 -0.946800618951241 0.344161525695981 ATG101 other 0.0018209570959717 1 0.00736134778582371 5.00411344313832 -0.946800618951241 0.365121351751352 6.03544385539595 4.64365024205168 1.29971973357092 0.194251591679968 13.1036154779229 14.6435715370396 0.894837399795433 0.371272688133341 NFE2 other 1 1 1 1.29971973357092 0.894837399795433 0.00727067230000362 46.2639000228414 19.4183621742194 2.38248208617012 0.0175440377408501 156.955376084257 59.6904114472778 2.62949060458211 0.00879688281498829 HOXC12 other 1 1 1 2.38248208617012 2.62949060458211 5.78963722160383e-08 3.30901482765281 6.50868343671532 0.508400025877237 0.611380846441743 -105.582068172059 19.1992819694285 -5.49927170923266 5.89723564539896e-08 IKZF4 other 0.000426985745093282 0.000786396373313951 1 0.508400025877237 -5.49927170923266 1.98810571381745e-26 154.925033457697 18.0998359413122 8.55947169687249 1.18193221882527e-16 -295.187866217667 57.0771329879875 -5.17173604847658 3.27308504891761e-07 SMUG1 other 2.61893165681172e-22 0.00423929975535809 1.55589557286159e-12 8.55947169687249 -5.17173604847658 1.57836922924475e-09 2854.68612821406 517.288879305634 5.51855306080802 5.32492574354329e-08 7568.22655263179 1607.87980193934 4.70696039809904 3.20375676561817e-06 TUBA1B essential 1.27895258645702e-05 0.0397361951639621 0.00055230129812031 5.51855306080802 4.70696039809904 0.0141775817418105 12.0941636342486 7.97661177993329 1.51620311579834 0.130069856214829 -47.2461423933731 22.7806964579407 -2.07395513480469 0.0385703730646749 EEF1AKMT3 other 1 1 1 1.51620311579834 -2.07395513480469 2.06694705140874e-27 113.171659235739 17.5961396337694 6.43161861585524 2.78694652304047e-10 -356.327754200775 50.0164659905467 -7.12420894087404 3.37050648704374e-12 KBTBD4 other 2.75627389305355e-23 4.9236358762735e-08 3.1673647234355e-06 6.43161861585524 -7.12420894087404 5.82073408298553e-05 -16.3039081111358 12.0336179675359 -1.35486336321464 0.176020379389154 -123.629803215735 27.8028813473491 -4.44665434748269 1.05671361948091e-05 SARDH other 0.326135730669679 0.127407961100813 1 -1.35486336321464 -4.44665434748269 8.26989407551893e-13 132.511124905951 41.8304809368229 3.16781260789433 0.00162227263381244 -461.625175494583 86.6282551902557 -5.32880610928555 1.45129515655371e-07 ATPAF1 other 7.83324366833154e-09 0.00190779684897727 1 3.16781260789433 -5.32880610928555 1.2701632786539e-14 273.827619889673 34.1689279665556 8.01393652612381 6.85653011216254e-15 82.5125748378987 70.5218036110531 1.17002927623601 0.242503413237454 STIL essential 1.29239113603034e-10 1 8.75030372914183e-11 8.01393652612381 1.17002927623601 4.82655149069703e-11 143.835353244895 25.1854252949228 5.71105516625486 1.84429979177926e-08 280.713269053424 48.8583367622014 5.7454528266012 1.52328043412256e-08 HJURP essential 4.22902441614874e-07 0.000207120440627645 0.000195311347949424 5.71105516625486 5.7454528266012 0.208409738680211 -91.7703488044598 185.797814427136 -0.49392587898524 0.62156086811879 -1023.855437228 581.231334664828 -1.76152828687121 0.078719102109072 COL10A1 other 1 1 1 -0.49392587898524 -1.76152828687121 9.32893544887636e-16 467.363358128728 66.1242511881055 7.06795691038083 4.87981952215217e-12 -250.065531404071 187.743260424757 -1.33195477077747 0.183436939058237 AMD1 other 9.87467817263563e-12 1 5.83821607630286e-08 7.06795691038083 -1.33195477077747 4.57934391069107e-31 111.907779582798 11.3068930747379 9.89730590384947 2.5267130812543e-21 -37.0736562451743 25.7053487164503 -1.44225455387224 0.14981462705096 NDUFAF4 other 6.33002708774826e-27 1 3.51465789602473e-17 9.89730590384947 -1.44225455387224 8.28389455438722e-31 42.4319648384844 6.23352543721814 6.80705730101596 2.68089946825167e-11 -76.4001701451671 14.2470991385696 -5.36250709018632 1.22308945375314e-07 USP45 other 1.14127215275793e-26 0.00161276575371889 3.14040563711001e-07 6.80705730101596 -5.36250709018632 1.8829588914526e-07 43.4354451050843 13.2093851076708 3.28822611734296 0.00107371649389887 -113.454751909257 32.7404051362638 -3.46528246785782 0.000571710636971709 METTL8 other 0.00133595933348562 1 1 3.28822611734296 -3.46528246785782 0.0013723252374668 44.938090903315 21.5163569215005 2.08855481749376 0.037215572007702 -120.442309924369 53.2720245124786 -2.26089229809834 0.0241630981293541 TTC21B other 1 1 1 2.08855481749376 -2.26089229809834 0.00983856240295184 75.8785012705421 28.1010212961212 2.70020439723362 0.00715122431019014 -30.5936098993808 66.7781893206767 -0.458137757411581 0.647041252866306 NMI other 1 1 1 2.70020439723362 -0.458137757411581 0.00485048498875167 -26.9107251323048 15.0330202661547 -1.79010768666969 0.074007308391418 -113.799363592699 35.7238928370698 -3.18552527608671 0.00152995539978524 TNFAIP6 other 1 1 1 -1.79010768666969 -3.18552527608671 0.121740614290302 46.1424239945511 30.7779628900084 1.49920331502935 0.134403109535152 -66.9553468478603 76.4064827456179 -0.876304528645515 0.381252712112193 ACVR1C other 1 1 1 1.49920331502935 -0.876304528645515 8.98108071263034e-09 -1.19113969321803 18.0790859682493 -0.0658849510041561 0.947493538293037 -267.737538423852 45.3720807338591 -5.90093145593942 6.34807962337208e-09 BAZ2B other 6.96572620071609e-05 8.72543544232492e-05 1 -0.0658849510041561 -5.90093145593942 0.0157437643458728 22.0828504659504 14.9317305016398 1.47892104425039 0.139735987484793 99.2852614161325 34.9116048158027 2.84390425304056 0.00462284285050738 SLC36A1 other 1 1 1 1.47892104425039 2.84390425304056 1.50626712044074e-09 574.020699570792 89.9734077510541 6.37989283632604 3.84529463454867e-10 -335.076070750243 578.086086305814 -0.579630056297505 0.562408572827923 LPGAT1 other 1.22233576823766e-05 1 4.34979729060146e-06 6.37989283632604 -0.579630056297505 0.516541407717357 -0.323255813953511 0.988703927073778 -0.326949054314203 0.743834056003024 6.36356589147283 6.06443652235999 1.04932517110368 0.294501377650531 BATF3 other 1 1 1 -0.326949054314203 1.04932517110368 0.220868926792073 72.4919354519824 56.3034822229119 1.28752135018894 0.198469313948365 -414.615965285185 381.243826365136 -1.08753489659944 0.277290184690191 G0S2 other 1 1 1 1.28752135018894 -1.08753489659944 0.00817319195474015 -3.6767398979335 5.04540395127841 -0.728730530486441 0.466492692506349 49.1626786233283 17.113423021687 2.87275541316468 0.00423436916907764 KCNJ2 other 1 1 1 -0.728730530486441 2.87275541316468 3.43417312434461e-32 199.895935190714 16.1765286368713 12.3571589231505 4.50859416278393e-31 42.0653032611883 39.0522030837926 1.077155702866 0.281890787542665 EXOSC9 essential 4.7944490988975e-28 1 6.65558670310163e-27 12.3571589231505 1.077155702866 5.86205508549919e-25 109.958719530512 45.9659472170603 2.39217782266653 0.0170877740519368 -898.869443767763 100.298755737186 -8.96192018695702 5.115844803163e-18 PLA2G12A other 7.57084414292221e-21 7.82263828851654e-14 1 2.39217782266653 -8.96192018695702 6.16598016575795e-08 -1.99452244032943 3.87610075632809 -0.514569296753495 0.60706224623346 -69.9854522808854 12.3601495115804 -5.66218492869485 2.41812503412835e-08 B9D2 other 0.000453322861786525 0.000326543604608692 1 -0.514569296753495 -5.66218492869485 1.02921030711119e-15 91.9261966718457 18.3148702947443 5.0192109030783 7.03284268056727e-07 -363.092302288289 69.8103727126892 -5.20112252920677 2.80602183245961e-07 COQ8B other 1.08818405770866e-11 0.00364333874726556 0.00683170337990305 5.0192109030783 -5.20112252920677 0.168687762131985 94.089240856013 49.7924350212534 1.88962923415679 0.0593479605864117 11.5987981156828 387.160764829193 0.0299586093668349 0.976111235537499 PFKFB2 other 1 1 1 1.88962923415679 0.0299586093668349 0.772414483373932 28.9601428555565 45.7704907575311 0.632725198621371 0.527183444348106 -122.728992238162 355.966316362425 -0.344776981969289 0.730397533059606 C4BPA other 1 1 1 0.632725198621371 -0.344776981969289 0.637556027720222 -3.22582247193536 5.41767603249339 -0.595425502113447 0.551810392289093 -30.6060035032337 41.4730258232411 -0.737973728603192 0.460853377784687 C4BPB other 1 1 1 -0.595425502113447 -0.737973728603192 4.38595599260743e-05 55.6347278918505 21.695668967494 2.56432415037335 0.0106131493608016 -96.014905156382 49.1057279089714 -1.95526895221607 0.0510784554489903 RAB38 other 0.250350368058032 1 1 2.56432415037335 -1.95526895221607 2.34091813282168e-34 419.044966638936 31.4312916498449 13.3320950124239 2.95552597723756e-35 693.74177491106 247.472965571669 2.8033032752022 0.00524007400698145 AGO2 other 3.32433784042007e-30 1 4.4202846515565e-31 13.3320950124239 2.8033032752022 0.000919337581111517 166.229874259803 44.4568469637104 3.73912874197972 0.000204339178220972 79.4857751462412 97.9199445680133 0.811742444268153 0.417296438037677 CKS2 other 1 1 1 3.73912874197972 0.811742444268153 0.0119750638734425 491.001368738028 254.829494688791 1.92678390442072 0.0545280666345302 -974.651177114701 563.95240952244 -1.72825075424369 0.0845117719715601 ACSL3 other 1 1 1 1.92678390442072 -1.72825075424369 9.35396276704273e-05 384.813674107725 143.975584322479 2.67277035838113 0.00775064845215507 -857.758613385714 316.244084494338 -2.71233093500306 0.00689462350573534 CHPF other 0.510165129314511 1 1 2.67277035838113 -2.71233093500306 1.0148415839535e-14 238.675480256227 58.107736470189 4.10746476725478 4.62181715504429e-05 -766.480492392578 130.399355871919 -5.87794692134391 7.28503468713686e-09 DNPEP other 1.03605177305813e-10 0.000100016241219702 0.393871257952874 4.10746476725478 -5.87794692134391 0.931265631847434 -3.72501478709785 13.4964421487613 -0.275999759495115 0.782653647616081 -9.43086328892103 29.7698889124449 -0.316792021517372 0.751523623766519 INHA other 1 1 1 -0.275999759495115 -0.316792021517372 0.000971753721194879 303.568604518567 86.5929102389345 3.50569814181016 0.000493272683387928 -87.4843236036279 190.109941904265 -0.460177530576928 0.645574033688281 OBSL1 other 1 1 1 3.50569814181016 -0.460177530576928 0.000496388695952846 -6.71161512053927 3.0907695750233 -2.17150290813532 0.0303246111516671 -24.6153722021684 6.58048256188985 -3.74066369307407 0.000203014927645406 FAM124B other 1 1 1 -2.17150290813532 -3.74066369307407 0.00316730662500929 8.88958049248615 30.148478510433 0.29486000394381 0.768216506265179 -173.729479011246 67.4626199912333 -2.57519614615949 0.010288830751653 SLC12A4 other 1 1 1 0.29486000394381 -2.57519614615949 4.32218671452039e-10 47.8440753877614 16.8977783984443 2.8313825793908 0.00481287668235835 -120.855142115409 37.0816575389953 -3.25916234969586 0.00118994137776892 ENKD1 other 3.61161921865323e-06 1 1 2.8313825793908 -3.25916234969586 7.26191590881723e-38 990.573760186203 69.9103011054638 14.1692103241247 7.41739513820825e-39 248.661879218563 557.105886344753 0.446345812014422 0.655530462228416 FAM210B other 1.05326828341485e-33 1 1.11883988264733e-34 14.1692103241247 0.446345812014422 0.662956442669481 16.6514302185672 25.3519836005499 0.656809758199987 0.511581513872599 119.384240626985 169.253921021671 0.705355834041208 0.480891286119956 PI3 other 1 1 1 0.656809758199987 0.705355834041208 6.68212415783901e-90 97.5048134912312 3.96055314236172 24.6189888094995 1.18560771307043e-89 -41.729446926557 32.7160264278553 -1.2755047443973 0.20269259715901 FAM209A other 1.04180997744868e-85 1 1.84931091084726e-85 24.6189888094995 -1.2755047443973 3.76947652510032e-18 94.9239951795802 11.1784577276112 8.49168977444132 1.98806117624205e-16 -192.597844840355 73.257198493544 -2.6290637480128 0.00880641302610614 SNX21 other 4.27043995528616e-14 1 2.60634820205332e-12 8.49168977444132 -2.6290637480128 0.117889492244393 -28.9744564793215 150.888645809759 -0.192025425928022 0.847794077533193 2042.90557005716 1011.04906801367 2.02058004372695 0.0438136166128347 SLPI other 1 1 1 -0.192025425928022 2.02058004372695 6.43710836981644e-12 7.59199396993508 1.03239234034749 7.35378757980684 7.20818454069649e-13 6.1676409198717 6.87205769965953 0.897495508539934 0.369855272233099 WFDC3 other 5.89124158005601e-08 1 8.78533531820089e-09 7.35378757980684 0.897495508539934 2.50167191193897e-22 118.006131625396 11.4669624557812 10.2909669479124 8.68203309594731e-23 -33.6577244786223 71.1330194183783 -0.473165974871107 0.636287403696616 TTPAL other 3.10057216765716e-18 1 1.22399302586665e-18 10.2909669479124 -0.473165974871107 0.000492762288379636 428.307251517749 191.411569503341 2.23762467769887 0.0256548622101963 -4262.04189365032 1448.75318909053 -2.94186886057926 0.00340321405318997 PREX1 other 1 1 1 2.23762467769887 -2.94186886057926 0.524794433731167 4.27276043702191 4.07728980473567 1.04794131436505 0.295131862011453 15.6783938524674 27.4799514517178 0.570539357757392 0.568547947223154 KCNS1 other 1 1 1 1.04794131436505 0.570539357757392 2.13590100682781e-08 16.7623332140485 2.83819406306968 5.90598558152116 6.21773595508123e-09 37.1321100518587 17.7314821860234 2.09413458290179 0.0367153222874338 SLC12A5 other 0.000162029450377958 1 6.7126677371057e-05 5.90598558152116 2.09413458290179 0.0870873186097034 -53.8675052231203 31.3327140511754 -1.71920967762764 0.086156791752717 -306.211878333806 186.53066154829 -1.64161685693981 0.101259302986422 ARHGAP40 other 1 1 1 -1.71920967762764 -1.64161685693981 8.09097109627897e-16 1663.66829982086 209.892620139277 7.92628296658029 1.2936384004564e-14 -3212.38636709269 1385.34884289869 -2.31882849114821 0.0207753501337592 SDC4 other 8.57966575049422e-12 1 1.64266204089953e-10 7.92628296658029 -2.31882849114821 2.55849496083832e-33 474.309794143688 37.6068566330826 12.6123222361116 4.17636339880196e-32 -413.270745319344 226.295510576512 -1.82624367698013 0.0683717616791018 NCOA3 other 3.60568694830945e-29 1 6.18394128460607e-28 12.6123222361116 -1.82624367698013 6.70783390224938e-21 1130.2998002479 124.736760939637 9.06148108812023 2.33349487546552e-18 -2625.9860363431 825.437260478159 -3.1813272335464 0.00154994382390658 PIGT other 8.09501395323456e-17 1 3.1499847323909e-14 9.06148108812023 -3.1813272335464 0.0951496440062966 13.7892545753228 6.45311463077598 2.13683707237426 0.033057484788782 28.9828370167821 43.0170434985364 0.673752416708233 0.500755418016367 MATN4 other 1 1 1 2.13683707237426 0.673752416708233 4.74156488810986e-20 149.370763253413 16.5583892598838 9.02085105676889 3.28597985335345e-18 -270.631407525096 103.447747992722 -2.61611695543278 0.00914345235484296 NCOA5 other 5.62159933134305e-16 1 4.42785785239378e-14 9.02085105676889 -2.61611695543278 7.63861166740596e-77 589.2901398469 26.4805103929257 22.2537304267492 4.436661134185e-78 9.86858340649976 248.679367926869 0.0396839652954317 0.968359945048248 VAPB other 1.18620000583147e-72 1 6.90433205701869e-74 22.2537304267492 0.0396839652954317 5.52128977027928e-06 248.574096881393 60.5269756130921 4.10683161290527 4.65033656768112e-05 -1094.62123380653 475.165059940316 -2.30366524412384 0.021630448551722 PARD6B other 0.0343313797915965 1 0.396115668835077 4.10683161290527 -2.30366524412384 3.09609236629698e-34 1198.8393065404 90.5833776842388 13.2346500780683 1.0040228708881e-34 -481.295615251619 693.557218803579 -0.693952282815077 0.48801790361913 ATP5E essential 4.39490311395857e-30 1 1.49910654852302e-30 13.2346500780683 -0.693952282815077 3.63523629214309e-14 328.997664466287 49.1592457916215 6.69248803899184 5.64345021771547e-11 -1045.02732754557 301.436958933992 -3.46681883748172 0.000569831842895117 CHD6 other 3.63778095754759e-10 1 6.54245183739755e-07 6.69248803899184 -3.46681883748172 1.11422413085322e-17 294.732895542784 33.0734720973113 8.91145914996763 8.33078784367073e-18 -146.552029042498 198.140037511904 -0.739638645893028 0.45985050767024 PLCG1 other 1.24692822483783e-13 1 1.11740857347155e-13 8.91145914996763 -0.739638645893028 0.541428111608957 3.80116005277016 3.88132749001509 0.979345356079546 0.327855341956048 -8.98298971786973 24.8231800137578 -0.361879086921622 0.7175863493439 TOX2 other 1 1 1 0.979345356079546 -0.361879086921622 4.76661184653442e-18 355.739095540649 56.0170785062934 6.35054710146448 4.6246740660343e-10 -1992.46095511142 349.659652309024 -5.69828672525965 2.01162458748095e-08 SRSF6 other 5.38388808066063e-14 0.000272192922932047 5.21570741167348e-06 6.35054710146448 -5.69828672525965 1.27589895063918e-13 392.525741544845 53.4296786753029 7.34658622841923 7.60479650244576e-13 -957.247364351416 418.24573238168 -2.28871998023845 0.0224830797510194 ARFGEF2 other 1.25114651099678e-09 1 9.26416309927942e-09 7.34658622841923 -2.28871998023845 1.84081126487898e-19 483.501379249276 52.3297535464924 9.23951187386558 5.77837901986238e-19 -698.874727591053 364.564695768198 -1.91701153650769 0.0557677784394844 ZNFX1 other 2.15595815342626e-15 1 7.85686195330687e-15 9.23951187386558 -1.91701153650769 0.595228861142205 -1.76841221842692 1.78698717171042 -0.989605435574714 0.322825496353622 -4.88357977441492 14.1653991934544 -0.344754122896271 0.730418082989425 ZNF831 other 1 1 1 -0.989605435574714 -0.344754122896271 0.30155716064726 -8.34213574647756 6.13531277302627 -1.35969200839337 0.174514414847096 -42.5199115179728 48.302079184006 -0.8802915368507 0.379106488191618 EDN3 other 1 1 1 -1.35969200839337 -0.8802915368507 8.20026054328409e-52 1106.5130452904 64.5089399832123 17.15286355005 6.53229347002298e-53 284.294579294939 504.973818248244 0.562988751141906 0.573677516618482 CSE1L essential 1.24422553223249e-47 1 1.00407882927723e-48 17.15286355005 0.562988751141906 3.46573417436421e-45 644.446644920059 41.1994674930716 15.6421110304019 1.27187239405847e-45 -244.815903866096 315.427247441297 -0.776140634177959 0.438012161888969 TMEM189-UBE2V1 other 5.17884657675244e-41 1 1.93909665198154e-41 15.6421110304019 -0.776140634177959 4.31118164969624e-87 446.042248485894 18.3861742457355 24.2596552455359 3.37302553158768e-88 -92.9383675469884 177.092470459592 -0.524801349858602 0.599939089570557 RAB22A other 6.71725212839171e-83 1 5.25989601395783e-84 24.2596552455359 -0.524801349858602 0.79536254069035 -10.9235910135591 30.6419240673821 -0.356491680794519 0.721613192060779 -129.483371151612 212.718174489915 -0.60870854811586 0.542976483162889 PTGIS other 1 1 1 -0.356491680794519 -0.60870854811586 7.64084405286172e-41 788.789285905436 54.0299528156076 14.5991111374352 6.78100366887336e-41 -582.057821992797 422.944658215901 -1.37620327077325 0.169332316094171 STAU1 other 1.12289844200856e-36 1 1.02664395546743e-36 14.5991111374352 -1.37620327077325 4.36527846233707e-07 5.21696985531864 0.95959275996968 5.43664987164293 8.36953567094225e-08 13.7404095496259 10.2772149029214 1.33697793414051 0.181815553659721 CDH26 other 0.00300680380485778 1 0.000858965445908803 5.43664987164293 1.33697793414051 6.72677135101705e-06 6.30398377017218 4.00111212443347 1.57555788843703 0.115726676047024 134.919527067676 28.0863268646298 4.80374410359746 2.03192150997866e-06 SNAI1 other 0.0414839989217221 0.0254355934619128 1 1.57555788843703 4.80374410359746 1.96513282611176e-44 77.4275027582781 5.07091927755204 15.2689282791454 7.7683457058704e-44 -71.5014351127762 40.1163627844227 -1.78235089499541 0.0752687336558412 MOCS3 essential 2.92804791090653e-40 1 1.18125464803465e-39 15.2689282791454 -1.78235089499541 2.02970429612608e-58 479.777500493926 25.8458762393949 18.563019340108 1.12065624771522e-59 214.935723199009 246.555173768429 0.871755071750726 0.383735249848209 STX16 other 3.11214559725012e-54 1 1.7310777058457e-55 18.563019340108 0.871755071750726 6.01504291424996e-16 583.173947750665 68.458755798148 8.51861739161846 1.62016240342332e-16 -558.186108770191 670.488956994086 -0.832506043459138 0.405492074212782 PMEPA1 other 6.40181017363623e-12 1 2.12743525193516e-12 8.51861739161846 -0.832506043459138 4.51337614683945e-34 424.28401588171 31.8011867145215 13.3417667614262 3.3056098114224e-35 386.779292651948 219.894666171793 1.75892985212191 0.079167536913877 RNF114 other 6.39500266245682e-30 1 4.94320891200106e-31 13.3417667614262 1.75892985212191 5.74429364034364e-62 485.60945441939 25.3380882756647 19.1651970399749 9.63736113742521e-63 -16.683432221734 176.586197461598 -0.0944775552198075 0.924765118188911 DDX27 essential 8.84391448867307e-58 1 1.49109251518243e-58 19.1651970399749 -0.0944775552198075 0.508200429438058 2.82006138713604 3.56731962630807 0.790526693021508 0.429570512467911 -27.0808500902147 34.246705803089 -0.790757810281772 0.429435723877313 C20orf85 other 1 1 1 0.790526693021508 -0.790757810281772 4.46837360378438e-06 165.951662377114 36.0780763277541 4.59979242988217 5.30473042583805e-06 -432.240998481073 288.516499312169 -1.4981500174567 0.134694137034587 BCAS4 other 0.0280301076165394 1 0.0487663868047291 4.59979242988217 -1.4981500174567 9.47319811276023e-10 244.915391128532 39.9818904106745 6.12565810702996 1.74708152337248e-09 -385.173599462775 248.410651029906 -1.55055186992125 0.121598234038892 KCNK15 other 7.76139121378446e-06 1 1.92475971429946e-05 6.12565810702996 -1.55055186992125 1.8990709813499e-05 3.42873116948907 0.953566165858617 3.59569298099178 0.000353080108092806 -16.0977657803449 6.30198970511772 -2.55439417288674 0.0109095487355173 TP53TG5 other 0.112614909194049 1 1 3.59569298099178 -2.55439417288674 0.661536168404673 10.1299946418602 23.182404446562 0.43696911013743 0.662309080983797 -173.219043416653 230.975702550348 -0.749944870841534 0.453615728272931 PCK1 other 1 1 1 0.43696911013743 -0.749944870841534 0.222915284586966 3.56115667361399 4.50147468244084 0.79110889760309 0.429228414779171 70.9093475732059 44.2599041044256 1.6021125442546 0.109716575052659 ZBP1 other 1 1 1 0.79110889760309 1.6021125442546 0.000161173378953795 3.01462708431283 0.81711377084394 3.68936027255939 0.000247730882945099 -8.15365422607758 5.2518457583079 -1.55253116738611 0.121124306969749 NEURL2 other 0.853090694802435 1 1 3.68936027255939 -1.55253116738611 2.93115729959253e-26 50.5830299717873 4.76157750043663 10.6231663702101 4.52481316725597e-24 -63.8157491096162 21.8476625187209 -2.92094172797357 0.00363538595079254 FASTKD3 other 3.85300627031438e-22 1 6.44423891280595e-20 10.6231663702101 -2.92094172797357 9.45645643937992e-12 186.429922961308 26.018879171708 7.16517885843541 2.5775175203467e-12 26.087917635875 116.99513227385 0.22298293210021 0.823633581261457 PEPD other 8.58362551002515e-08 1 3.10539310851371e-08 7.16517885843541 0.22298293210021 0.951919130530768 -10.018470474727 34.889420417706 -0.287149237642329 0.774107798116325 -29.264515669657 156.986856686167 -0.186413794679384 0.852190025650411 CHST8 other 1 1 1 -0.287149237642329 -0.186413794679384 8.44072496633372e-17 193.390180608452 22.8776555943621 8.45323419660668 2.62050505961664e-16 -114.219739100187 78.4994658009618 -1.45503842522693 0.146236458696186 STAMBP other 9.21558351824315e-13 1 3.42866882000241e-12 8.45323419660668 -1.45503842522693 0.00381342426824415 118.122491955047 47.1166192653345 2.50702392906943 0.0124667532625684 -283.125842956396 158.488016604626 -1.78641798302453 0.0745904473349508 NAGK other 1 1 1 2.50702392906943 -1.78641798302453 0.0423106697036899 2.48119466064353 7.66772386922263 0.323589464482773 0.746372996349978 -62.3138568177538 25.8073557497999 -2.41457735623445 0.0160818117768712 MCEE other 1 1 1 0.323589464482773 -2.41457735623445 0.00273178707395704 60.4310066757764 18.2337774348292 3.31423408516243 0.000980004747901883 92.3694702286832 61.3696566215833 1.50513259016993 0.132869301262197 PAIP2B other 1 1 1 3.31423408516243 1.50513259016993 3.87062386006607e-11 76.798191444997 12.0853488920902 6.3546524085259 4.41513977547104e-10 -86.2691492468491 40.7901112504463 -2.11495253634311 0.0348872326020713 SNRNP27 essential 3.41040668310421e-07 1 4.9855758344619e-06 6.3546524085259 -2.11495253634311 2.00533473528036e-14 202.289600539274 26.0780625601716 7.75707934868698 4.30407270196996e-14 -112.52575859711 87.7712668367277 -1.28203411722917 0.200375762886408 MPHOSPH10 essential 2.02498701568611e-10 1 5.40763694275505e-10 7.75707934868698 -1.28203411722917 0.00370157500977637 44.850901550652 32.6882045954543 1.37208213500013 0.170603386312549 -139.28244407789 68.5918222552506 -2.03059839348747 0.042781625528778 ATP8A1 other 1 1 1 1.37208213500013 -2.03059839348747 1.66025722549783e-49 1523.03703995512 123.028907147389 12.3795055590514 3.52594299556526e-31 -1649.07528998992 358.746990137963 -4.59676411321454 5.34234860229014e-06 USP22 other 2.50665635905662e-45 0.0655613020473047 5.20676002155122e-27 12.3795055590514 -4.59676411321454 0.356792188423556 8.08119501527742 5.99910927855904 1.34706581261318 0.178517836741945 16.4855677626393 17.4722379417012 0.943529261543136 0.345827562501082 HIF3A other 1 1 1 1.34706581261318 0.943529261543136 4.43962026918244e-18 33.6145752845516 6.70917148403493 5.01024237710132 7.34955003996167e-07 -122.717057757845 21.0813061316389 -5.8211316220901 9.96771389110721e-09 ZNF576 other 5.01943467633767e-14 0.000136288552033109 0.00713053344877081 5.01024237710132 -5.8211316220901 6.77084628971201e-17 35.5403974142149 8.75375728775923 4.06001631595528 5.62475257970423e-05 -178.089150897854 28.3574854750261 -6.28014606777085 6.90896677622981e-10 ZNF45 other 7.41339960260568e-13 9.71331639070148e-06 0.475966563294572 4.06001631595528 -6.28014606777085 0.230986159881055 -27.8121135591448 110.64818417488 -0.251356258275216 0.801633254547346 -599.107749902685 354.753657962822 -1.68879935824501 0.0918288433040634 LYPD3 other 1 1 1 -0.251356258275216 -1.68879935824501 0.220437440965395 2.55116461357254 2.89604538440291 0.880913202297249 0.378768660547492 -13.0107023222615 10.9777894984891 -1.18518416882125 0.236481851758132 CEACAM8 other 1 1 1 0.880913202297249 -1.18518416882125 0.507732433652909 -85.5427478425543 89.4781080189552 -0.956018737280774 0.339493745389726 -256.709692928877 269.222727266912 -0.953521626999829 0.340755648320895 F13A1 other 1 1 1 -0.956018737280774 -0.953521626999829 0.149049437154748 -50.804104861241 27.9035180693585 -1.82070607494581 0.0692038310584538 8.24319438926465 95.519844902401 0.0862982388391363 0.931261267716475 GRM4 other 1 1 1 -1.82070607494581 0.0862982388391363 0.00249105766962015 -6.74801441302096 22.1324792190969 -0.304891934889901 0.760565499245683 -361.120497384847 105.205531317105 -3.43252386888649 0.000643665308640552 TRERF1 other 1 1 1 -0.304891934889901 -3.43252386888649 0.0264133143427818 20.5301064910105 7.61682524306434 2.6953626787886 0.0072499579743246 28.1544500808328 25.9509435550228 1.08491045888709 0.278444531839642 PACSIN1 other 1 1 1 2.6953626787886 1.08491045888709 9.92863553447563e-09 61.6727347975735 10.4111127074221 5.92374096129102 5.66018493487771e-09 -2.54493600793271 42.2097204779733 -0.0602926524770701 0.951945238510706 BTN2A2 other 7.67781385881001e-05 1 6.11922593309629e-05 5.92374096129102 -0.0602926524770701 1.69952869997225e-20 102.361924260905 11.1506585492392 9.17989944799172 9.28476057041894e-19 -45.0154379876479 38.0552244223212 -1.18289771433444 0.237373128651085 SIRT5 other 2.03246637229682e-16 1 1.25957061898303e-14 9.17989944799172 -1.18289771433444 9.37204655756804e-33 208.087646319921 18.0475483115356 11.5299675461689 1.22224828474538e-27 -154.699753268874 63.1598972655872 -2.44933509974472 0.0146298644024571 MRS2 other 1.31546045482025e-28 1 1.77666010670589e-23 11.5299675461689 -2.44933509974472 6.31217200220197e-48 477.419463363089 30.7556403117037 15.5229889062467 4.8630466217276e-45 -13.3874417912679 95.5673038367873 -0.14008391211006 0.888647112105099 WRNIP1 other 9.49603156011265e-44 1 7.40690630955331e-41 15.5229889062467 -0.14008391211006 5.11456401077046e-56 246.354263315608 14.7166185882843 16.7398687298811 6.34247632918759e-51 -168.695985905911 71.3380952450037 -2.36473913869639 0.0183974377306889 RRP36 other 7.81403089565512e-52 1 9.72935868897377e-47 16.7398687298811 -2.36473913869639 1.86183217659757e-07 8.41244247750981 1.74134913596002 4.83099127210465 1.77935166877409e-06 -10.2818683705121 7.01394944526787 -1.46591709146821 0.14326166309676 BTN2A3P other 0.00132152847894896 1 0.0168611364133032 4.83099127210465 -1.46591709146821 7.11027433594994e-26 412.817052898846 39.221098049046 10.5253823435187 1.03907351782811e-23 -79.9980419524857 132.101072726373 -0.605582076673892 0.545044404312339 SNRPC essential 9.30663807832487e-22 1 1.47610783942661e-19 10.5253823435187 -0.605582076673892 3.93449418100995e-09 244.50568682602 75.8417550357961 3.22389278453034 0.00134277085990079 -989.996395275617 236.466735091701 -4.1866201387341 3.31712642932746e-05 SERPINB6 other 3.12065414270613e-05 0.386810112923875 1 3.22389278453034 -4.1866201387341 1.49010916164557e-67 669.7924410871 33.8312924966538 19.798015140963 5.38762482051443e-66 -27.6203027661417 180.221203781979 -0.153257786467541 0.878252240608031 XPO5 essential 2.30311272023939e-63 1 8.34650837194095e-62 19.798015140963 -0.153257786467541 1.71799257745516e-53 115.227974053587 7.08798042838165 16.2568132372646 1.19308100954754e-48 -97.7807299646635 37.4961084660027 -2.60775675036571 0.00936639661319184 ABCC10 other 2.61444110437126e-49 1 1.82612979321347e-44 16.2568132372646 -2.60775675036571 0.962485891987368 -0.025066636665741 2.45434823251346 -0.0102131540804504 0.991855052383275 -2.67410897258376 9.95490675161017 -0.268622202026275 0.78832455924241 HIST1H1D other 1 1 1 -0.0102131540804504 -0.268622202026275 3.69585624478358e-29 304.990505991917 26.4593455119215 11.5267592637354 1.25931834971483e-27 -128.823511685566 129.526711663783 -0.994571004164437 0.320392060004893 PEX6 other 5.01934236604058e-25 1 1.8304192213105e-23 11.5267592637354 -0.994571004164437 5.54037207302218e-11 150.071666341392 24.9285061773255 6.02008260237807 3.26174803254276e-09 -111.402374932236 74.2215019382689 -1.50094476698802 0.133966458676659 NQO2 other 4.84173115461409e-07 1 3.55628387988137e-05 6.02008260237807 -1.50094476698802 3.45327836558336e-53 388.281870461377 23.6313478194422 16.4307966446978 1.7696762542805e-49 -192.450397220523 113.669227959165 -1.69307384835638 0.091019235429795 PRICKLE4 other 5.25278172188884e-49 1 2.71079008630687e-45 16.4307966446978 -1.69307384835638 2.76685604090844e-22 74.8273085079439 10.0252978224529 7.46384893826885 3.36199059326893e-13 -232.411299055089 45.3491204848806 -5.12493509400198 4.14418973039214e-07 OARD1 other 3.42647452106102e-18 0.00534724800912497 4.13390363348348e-09 7.46384893826885 -5.12493509400198 0.805158079272007 3.82392415917877 37.7396799959698 0.101323703846644 0.919330902261659 -102.861805066331 170.714259616811 -0.602537862374335 0.547067706423165 UNC5CL other 1 1 1 0.101323703846644 -0.602537862374335 1.37557416265206e-48 107.9271515343 7.34171033982372 14.7005461314471 2.8031096113035e-41 -154.845170110578 38.5666017065127 -4.01500685201491 6.80234136165763e-05 AARS2 essential 2.0720273612028e-44 0.776351219605986 4.24615043920255e-37 14.7005461314471 -4.01500685201491 4.73966248045902e-16 43.4210734192255 5.40320710515794 8.03616677542778 6.04159143205516e-15 -17.2419618319297 20.7800103875765 -0.829737883203269 0.407059855210441 ZNF391 other 5.05816779914586e-12 1 7.71752889530726e-11 8.03616677542778 -0.829737883203269 6.28976737131455e-10 428.035179833186 78.7554035721643 5.43499443109289 8.30124433778808e-08 -498.010649891009 268.324002131371 -1.85600485210109 0.0639964105751557 RPS10 other 5.20792738344845e-06 1 0.000852122731273947 5.43499443109289 -1.85600485210109 0.00971471955284385 -28.2734369089923 16.169901732696 -1.74852249422286 0.0809397251571746 -207.952317851219 72.4997531481551 -2.86831759863048 0.00428737866789543 MOCS1 other 1 1 1 -1.74852249422286 -2.86831759863048 1.18211276335498e-05 24.7147142093539 5.13924867042187 4.80901310566962 1.97551183350795e-06 31.8663351938868 20.3323543943189 1.56727226841918 0.117643421665504 HIST1H2BJ other 0.071387789779007 1 0.0186685868266501 4.80901310566962 1.56727226841918 1.98122033994876e-73 216.406988724548 10.5673462655711 20.478839557819 2.10229235053736e-69 -73.5965514065621 50.8322567051679 -1.44783167572963 0.148244452414338 MED20 essential 3.07227838115854e-69 1 3.26107589415355e-65 20.478839557819 -1.44783167572963 3.37076161925721e-50 141.478183257962 9.16392560173057 15.4386001596569 8.82803546278803e-45 -118.818468949057 43.5998702594676 -2.72520235133626 0.00663544914445753 TBCC essential 5.09996232993615e-46 1 1.34371527779097e-40 15.4386001596569 -2.72520235133626 0.00172737571388265 133.668029353459 215.275246776152 0.620916855770462 0.53491583274813 -2306.42520883669 733.454634917418 -3.14460513170849 0.00175442819754948 SPDEF other 1 1 1 0.620916855770462 -3.14460513170849 2.87420631349419e-39 96.5248097317111 7.26730469092253 13.2820645117961 4.98432437634782e-35 -102.154715073073 38.7118919605268 -2.63884584037474 0.00855951928643028 MAD2L1BP other 4.19547895580747e-35 1 7.44807591557654e-31 13.2820645117961 -2.63884584037474 0.825760045209844 -12.046857851397 23.6643861027163 -0.509071217783002 0.610909099619198 -50.4506638865834 107.04510884149 -0.471302840761176 0.637613783338703 APOBEC2 other 1 1 1 -0.509071217783002 -0.471302840761176 2.38578108980532e-53 797.963739640168 47.8356521337637 16.681360116275 1.16396390527408e-50 -239.260625245667 233.506014931987 -1.02464437721382 0.305991502415192 KLHDC3 other 3.62972735002982e-49 1 1.78493864873781e-46 16.681360116275 -1.02464437721382 0.494054686975801 5.42495658411816 7.36963300631421 0.73612303074931 0.461975467828584 -26.1939510749165 36.0805615252038 -0.725985127937073 0.468162418599796 GNMT other 1 1 1 0.73612303074931 -0.725985127937073 0.0852545083726837 9.0497532558891 4.32505551688827 2.09240163982914 0.0368671474641568 25.3261955609886 20.1303527010845 1.25810987701295 0.208893739938592 TREM1 other 1 1 1 2.09240163982914 1.25810987701295 7.61079375185362e-41 365.072717218532 26.2671503221415 13.898451592246 9.61956838554717e-38 -217.853860326487 129.602653863082 -1.68093672338405 0.0933556162944546 MEA1 other 1.11855835770993e-36 1 1.44668688950244e-33 13.898451592246 -1.68093672338405 0.689679872774033 15.5968445197584 20.352422092917 0.766338495170378 0.443821991389971 -10.5101524833736 74.552027536027 -0.140977419806519 0.887942270587116 KLHL31 other 1 1 1 0.766338495170378 -0.140977419806519 0.0381273858893694 16.4810131677851 7.30101349745594 2.25735963555305 0.0243996562089662 -16.122283792082 29.756136035561 -0.541813754743378 0.588178892505402 COL21A1 other 1 1 1 2.25735963555305 -0.541813754743378 0.547888415155894 93.1126749613147 120.19815031324 0.774659798995744 0.438876656657134 400.559122942535 405.803443966313 0.987076696608288 0.324043050369311 CDKN1A other 1 1 1 0.774659798995744 0.987076696608288 7.27101561701596e-08 965.908759152613 180.322510929681 5.35656227374341 1.2655353235139e-07 -551.739551077295 669.784386749999 -0.823756961183442 0.410447493586675 SOX4 other 0.000531220400979186 1 0.00128439179983426 5.35656227374341 -0.823756961183442 2.54053094938282e-18 907.660447815213 108.890362796792 8.33554434481096 6.33617915348638e-16 -518.97655215413 378.134906348139 -1.37246401599413 0.170484616232543 GLO1 other 2.89087016730271e-14 1 8.2357656637016e-12 8.33554434481096 -1.37246401599413 0.795883877776813 -4.83586655987919 7.79147544189511 -0.620661208001315 0.535082493667933 -12.1264736415206 26.5420049523027 -0.456878584090106 0.647940694054264 CPNE5 other 1 1 1 -0.620661208001315 -0.456878584090106 0.138451344022804 -10.3005702393543 6.92532981507772 -1.48737612711644 0.137495940276735 -41.1212213753507 23.7233341392724 -1.73336602409849 0.0835982999450679 KCNK17 other 1 1 1 -1.48737612711644 -1.73336602409849 5.96923056891473e-08 -44.4677034556594 36.8119748101635 -1.20796843106016 0.227591117928157 -643.694122357555 111.13452944554 -5.79202634472836 1.18505335862136e-08 RREB1 other 0.000439514446789192 0.000161605726515194 1 -1.20796843106016 -5.79202634472836 1.33768241241592e-19 907.638385881844 111.028903420399 8.17479375118356 2.1308872507965e-15 -684.495549729675 336.268886276819 -2.0355601652845 0.0422831197564964 SSR1 other 1.57124176162374e-15 1 2.74415660157573e-11 8.17479375118356 -2.0355601652845 2.37533422257825e-14 200.689048421189 25.3673556882019 7.91131132814631 1.44966174310489e-14 70.9233366559358 76.8307549353494 0.923111281616528 0.356361488522552 RIOK1 essential 2.39148649529178e-10 1 1.83889592112855e-10 7.91131132814631 0.923111281616528 0.000297528641701023 93.6846972939075 23.8087415585715 3.93488656523216 9.4190848227143e-05 163.194751464072 71.8703569069051 2.27068235761596 0.0235621538499832 NRN1 other 1 1 0.780371177561879 3.93488656523216 2.27068235761596 4.03449584224524e-18 89.3049592514106 12.9939261169492 6.87282338283589 1.74198263424862e-11 -159.893013264582 41.0075240891199 -3.89911404836568 0.000108704649418272 SLC35B3 other 4.56745274300584e-14 1 2.05170714661802e-07 6.87282338283589 -3.89911404836568 1.74715670292195e-30 81.9921221671563 6.65798371658661 12.3148577192964 7.40688057332066e-31 34.9204727402408 20.5673650881563 1.69785835913176 0.0901160060170291 RPP40 essential 2.40041859414447e-26 1 1.09258895337053e-26 12.3148577192964 1.69785835913176 0.000121997010658576 -101.65251020474 39.0115011621673 -2.60570619372424 0.00942336081679611 -514.650006004224 129.065943640724 -3.9874965578591 7.60401645884252e-05 ATXN1 other 0.6564659143538 0.864652711534982 1 -2.60570619372424 -3.9874965578591 4.53859921878389e-18 433.10193066418 49.2076527243969 8.80151575385856 1.8261535966099e-17 -85.6840098346641 178.534955663846 -0.479928479641791 0.631472582598454 NUP153 essential 5.12952483706955e-14 1 2.43572366715829e-13 8.80151575385856 -0.479928479641791 2.66463083721763e-18 1256.96415102042 134.629777223755 9.33644975829785 2.62296022794154e-19 984.38283419219 491.536985669631 2.00266279627187 0.045715711793124 DEK other 3.02995172500017e-14 1 3.5800784151174e-15 9.33644975829785 2.00266279627187 2.46261955107846e-26 90.8288898137831 8.40430754114936 10.8074210003697 8.67535461694533e-25 -13.1694301136891 26.5490025643194 -0.496042368513994 0.620065605478404 EEF1E1 other 3.24154611508458e-22 1 1.24074921731552e-20 10.8074210003697 -0.496042368513994 0.56671561311788 15.8679213972291 16.7223444900344 0.94890530491616 0.34310370644511 56.0584339455336 78.8908933184731 0.710581812266118 0.477657755253875 RUNX2 other 1 1 1 0.94890530491616 0.710581812266118 2.81340613263841e-21 138.579104911949 123.017513613253 1.12649899060405 0.260450133829596 -2167.76062699032 238.653298182677 -9.08330470811682 1.93244034776887e-18 LRRFIP1 other 3.41660040747608e-17 2.96049861278192e-14 1 1.12649899060405 -9.08330470811682 5.51075229022177e-15 -18.6080991981073 37.9820795917481 -0.48991786121553 0.624388451286988 -590.833008006769 73.9239158476592 -7.99244738636878 7.89337255812361e-15 RAB17 other 5.68489206259278e-11 1.18392694999296e-10 1 -0.48991786121553 -7.99244738636878 0.939429203220724 2.39046958773799 13.1276335237622 0.182094479055271 0.855577043660045 14.0270010320445 40.4892708043725 0.346437482162056 0.72914915790091 EREG other 1 1 1 0.182094479055271 0.346437482162056 6.04078502701924e-05 24.2045015877493 7.27110541488181 3.32886132254524 0.000933706799645301 -28.0039485609556 18.5936699353316 -1.50610119779219 0.132647230492965 MYRF other 0.337921514411457 1 1 3.32886132254524 -1.50610119779219 0.00824322818297954 -3238.24835350463 1502.48030052238 -2.15526842673329 0.031597348325837 -10788.2284765792 3709.34366968309 -2.90839281481322 0.00378762857737489 SCGB1D2 other 1 1 1 -2.15526842673329 -2.90839281481322 0.345127596234082 -91.6609136158492 251.646148942362 -0.364245246752589 0.715822097122869 -897.098589414256 621.222770035898 -1.44408516990196 0.149313786475594 SCGB2A1 other 1 1 1 -0.364245246752589 -1.44408516990196 0.00370039849690727 -268.126090969345 1845.16856903024 -0.145312518037451 0.884525257106199 -14554.2976048457 4666.75780698054 -3.11871714942553 0.00192581474679701 AHNAK other 1 1 1 -0.145312518037451 -3.11871714942553 5.56113996572644e-57 687.312659020256 39.0617937661705 17.5955221906759 3.73837368664868e-55 -281.875683063045 119.75681862309 -2.35373389426945 0.0189419954702598 EMC3 essential 8.51132471754432e-53 1 5.75672164007029e-51 17.5955221906759 -2.35373389426945 0.442682961586078 1.88302033682506 1.50144126328362 1.25414185880768 0.210335078575108 -0.0551676128425574 3.78721378997016 -0.0145668071310524 0.988383180680265 SSUH2 other 1 1 1 1.25414185880768 -0.0145668071310524 4.62988933917059e-07 14.1807215773446 13.4825019649745 1.05178709516853 0.293363359757978 -131.460284346243 29.9102330718401 -4.39516081437727 1.33095837186466e-05 SH3TC1 other 0.00317980799814236 0.159541980035416 1 1.05178709516853 -4.39516081437727 3.71303969139644e-47 1433.27592462565 144.576706242778 9.91360200320822 2.15690653218203e-21 -1333.19969263762 311.759948399682 -4.27636615761957 2.24733227319515e-05 CNOT1 essential 5.57475779266261e-43 0.265364994818883 3.00241389279738e-17 9.91360200320822 -4.27636615761957 4.93462856488665e-07 9.09489734240643 3.54623052429358 2.56466613777686 0.0106054731365641 -18.6479419735995 7.81545824316236 -2.38603308896371 0.01738599076683 LRRC29 other 0.00338120749266034 1 1 2.56466613777686 -2.38603308896371 1.38311151488631e-29 170.173125854499 26.6875668070529 6.37649460832549 3.86227436299649e-10 -237.751757858463 57.3153947330841 -4.14813086371759 3.88665659272133e-05 BBS2 other 1.88462775018409e-25 0.451357430112728 4.36823230454902e-06 6.37649460832549 -4.14813086371759 0.0574415281426907 -81.4682844470437 104.756353817047 -0.777693013154365 0.437093133110366 -504.701689664218 223.665345518356 -2.2565037444426 0.0244411234972478 MT1G other 1 1 1 -0.777693013154365 -2.2565037444426 0.000855843738912753 -301.799719162848 360.212046565432 -0.837839050749309 0.402491777570348 -2621.56284680626 771.331355352066 -3.3987505222184 0.000726918508681389 MT2A other 1 1 1 -0.837839050749309 -3.3987505222184 6.22321691077955e-44 126.474873037701 19.3682930967744 6.52999582388412 1.55229895275954e-10 -322.494479012076 42.7626302750364 -7.54150240380182 2.05271088319004e-13 C16orf70 other 9.25890211985781e-40 3.03719102276799e-09 1.7772270710144e-06 6.52999582388412 -7.54150240380182 1.26597158705873e-33 919.213621854565 118.992799647194 7.72495163219935 5.47856620898564e-14 -1007.34952189668 256.640702010128 -3.92513546762712 9.78899496841221e-05 GOT2 other 1.78742528376822e-29 1 6.8662870297217e-10 7.72495163219935 -3.92513546762712 5.49270572036862e-14 79.8911454705765 16.3631165361996 4.88239176771955 1.37893399271197e-06 -78.7640914894834 35.6944908786223 -2.20661759141817 0.0277570061247564 DOK4 other 5.45590459204215e-10 1 0.0131577881584576 4.88239176771955 -2.20661759141817 0.503483901090922 -0.124473548809284 0.913950959539188 -0.136192809373539 0.891719804716075 2.36113084593703 2.24222136804169 1.05303199746027 0.292799035010801 GPR18 other 1 1 1 -0.136192809373539 1.05303199746027 2.95467877682088e-15 38.7862431729642 5.16656301408912 7.50716541484056 2.51163945680698e-13 -14.6252609019796 12.6747895668439 -1.15388589489785 0.249057386029893 CLYBL other 3.07552513879285e-11 1 3.09961425364549e-09 7.50716541484056 -1.15388589489785 4.90869458807242e-34 266.143959104397 21.9370584144767 12.1321625751228 3.90062051867145e-30 -57.2394982743752 52.3885716476477 -1.09259513046765 0.275056998207496 TMTC4 other 6.95365675346339e-30 1 5.73742272091384e-26 12.1321625751228 -1.09259513046765 3.0222955677915e-39 513.83045126064 35.4465519863873 14.4959219575988 2.05062010397953e-40 478.686390928531 91.7091943016421 5.21961178018941 2.56821591181623e-07 RAP2A other 4.41134261074848e-35 0.00333945115013464 3.10156290726904e-36 14.4959219575988 5.21961178018941 0.19082611084376 41.3874137507957 22.8732404027563 1.80942503213529 0.0709429724543388 46.7805432675035 57.3164545849684 0.816179988909711 0.414758420765431 ABCC4 other 1 1 1 1.80942503213529 0.816179988909711 5.31330656033776e-08 225.018809014132 44.3376531563684 5.07511771587332 5.34266071450624e-07 -122.103932288843 107.229447098101 -1.13871642159204 0.255328241098287 EFNB2 other 0.000392919020136977 1 0.00522939630735871 5.07511771587332 -1.13871642159204 2.37083103311118e-40 1853.90623792339 153.126056147561 12.107059272374 5.09917420494445e-30 -1464.22602679428 375.524230705033 -3.89915192435186 0.000108688116420974 TM9SF2 other 3.47824620867741e-36 1 7.49578608126833e-26 12.107059272374 -3.89915192435186 2.71079512873606e-28 54.5713505204012 4.5637106594032 11.9576709816081 2.18058489637587e-29 53.8079322640733 10.6784233473934 5.03893978666876 6.40277651356506e-07 C17orf53 other 3.64818808425299e-24 0.00820131643622548 3.19630134110776e-25 11.9576709816081 5.03893978666876 0.735556029066153 47.1606657761033 66.6709858898247 0.707364157686783 0.479642560485663 -5.51028569005011 156.19615478719 -0.03527798554041 0.971870994267097 IRF1 other 1 1 1 0.707364157686783 -0.03527798554041 9.55469225675886e-20 51.7274077695075 12.4861847053 4.1427713100825 3.97896231636816e-05 -224.161859162031 30.674761752005 -7.3076968282363 9.76736534853545e-13 ATP5S other 1.12621157630417e-15 1.43541201162077e-08 0.341116439382243 4.1427713100825 -7.3076968282363 1.12866581805716e-05 32.6907597908241 28.5239751838335 1.1460800810594 0.252269631611494 -262.730185406207 65.1827415560151 -4.03067098950461 6.36129441627754e-05 BMP4 other 0.0683181419669997 0.727922920054638 1 1.1460800810594 -4.03067098950461 0.00130162436129962 70.7637903183315 20.8585019869875 3.39256339513151 0.000742799817880153 -14.2085782567768 49.6107229628851 -0.286401354550035 0.774679774810009 PTGER2 other 1 1 1 3.39256339513151 -0.286401354550035 3.68445625381082e-31 15.9263418912077 20.3284995909352 0.783448961393564 0.433705721841073 -419.914771650846 39.829334215256 -10.5428518935675 9.12999873536923e-24 FAM193A other 5.09781367277266e-27 1.41880180347638e-19 1 0.783448961393564 -10.5428518935675 2.68864754457943e-16 7.95695431551251 2.42842189337517 3.27659470424781 0.00111739958794854 -25.4771537957097 4.72579010710169 -5.39108873189773 1.04386141082435e-07 GRK4 other 2.89379135223084e-12 0.00138081987423845 1 3.27659470424781 -5.39108873189773 1.80927617319178e-05 -13.171145323245 87.5965035362805 -0.150361541745668 0.880537574816783 1379.85878136309 298.40757407741 4.624074256926 4.7515547542879e-06 SOX9 other 0.107498916961906 0.0584298688134783 1 -0.150361541745668 4.624074256926 7.53117618644237e-05 2.70759649032298 3.3706205211603 0.803293183947897 0.422158078566487 -21.3128729176325 6.11964561282135 -3.48269724524238 0.000536549431259904 TEKT3 other 0.416323419586534 1 1 0.803293183947897 -3.48269724524238 0.681481615836114 1227.35286911395 2388.10538357696 0.513944182511575 0.607511030874716 3855.14513310239 4493.87916984767 0.857865774177696 0.391364865867409 MYH2 other 1 1 1 0.513944182511575 0.857865774177696 0.000461356219197278 46.4121432974161 13.0190768905572 3.56493349625111 0.00039634975101788 1.68305912074804 23.4531456690616 0.0717626174542659 0.942817492057492 HS3ST3B1 other 1 1 1 3.56493349625111 0.0717626174542659 4.67137980195543e-45 88.9944815136119 27.7639076087449 3.20540187525984 0.00142772849819149 -614.179410377008 49.3801130725618 -12.437788659465 1.94223410532469e-31 SLC25A35 other 6.97670573422043e-41 3.04095593870687e-27 1 3.20540187525984 -12.437788659465 3.96407262666223e-63 487.920770536312 26.0151461189846 18.7552577373475 9.68938163472405e-61 -103.116942079364 87.1342340078444 -1.18342627617614 0.237163869013492 MRPS7 essential 6.11061795399983e-59 1 1.49788150691199e-56 18.7552577373475 -1.18342627617614 1.29806453636595e-49 218.468823445942 13.5434301636551 16.1309816498498 5.42560509872595e-48 -39.6420130870274 45.38031357338 -0.873550885075446 0.382754808122583 GGA3 other 1.96072648218077e-45 1 8.29683531697172e-44 16.1309816498498 -0.873550885075446 8.62735319672962e-25 75.3441114849707 8.87282974305887 8.49155384097297 2.02153707526336e-16 -148.775181804863 29.1069045805647 -5.11133643198197 4.46029906255634e-07 ARMC7 essential 1.11154818586664e-20 0.00575110961126015 2.64962864454769e-12 8.49155384097297 -5.11133643198197 1.21655220422951e-57 311.923821246837 16.9831324679795 18.3666836394845 9.26453672174818e-59 167.473225227868 56.9255283537985 2.94197050200401 0.00340291492064683 NUP85 essential 1.86351466643877e-53 1 1.43053711520514e-54 18.3666836394845 2.94197050200401 1.91484556797459e-34 98.2004605828953 7.37536426038155 13.3146590617092 3.79747551284227e-35 109.642534800475 24.5339556396668 4.46901169998056 9.59331608686273e-06 SLC25A19 other 2.72137852120549e-30 0.11595441154191 5.67684614414791e-31 13.3146590617092 4.46901169998056 1.75503892112394e-48 180.972472650693 13.3362643231226 13.5699524443979 2.81914735517022e-36 -278.890928546268 44.6680241966207 -6.24363699900045 8.69259263627726e-10 MIF4GD other 2.6423865996442e-44 1.21939689501697e-05 4.22674762960671e-32 13.5699524443979 -6.24363699900045 1.2080562877947e-14 67.6514886413447 13.7534884028693 4.91886033998697 1.15966312978755e-06 -242.753852824089 45.0104461653337 -5.39327808332312 1.03931380448798e-07 NT5C other 1.2304053291189e-10 0.0013750121633376 0.0111176904252733 4.91886033998697 -5.39327808332312 3.45876174405109e-31 144.324493073899 11.4238180404849 12.6336477491524 5.21911302759379e-32 74.4832039032015 112.761349413134 0.66053842288026 0.509207778070915 MSTO1 essential 4.78727212994111e-27 1 7.72533110344433e-28 12.6336477491524 0.66053842288026 0.943087905849009 -0.409993989811621 1.21552762855213 -0.337297137622435 0.736023980023413 -0.676551299827768 10.9293389266847 -0.061902307574699 0.950663534356323 C1orf61 other 1 1 1 -0.337297137622435 -0.061902307574699 1.01045481875863e-33 83.4798746367868 8.28788829881689 10.0725144484276 5.41872087310244e-22 -87.5385047866717 19.0583709840606 -4.59317875908094 5.43149197952492e-06 TTF1 other 1.42847997727908e-29 0.0666226806208527 7.58079050147032e-18 10.0725144484276 -4.59317875908094 4.73396546153601e-13 310.10944179176 56.0530687964288 5.53242576098737 4.91011279081996e-08 -406.788100261311 128.436300015462 -3.16723621135409 0.00162511033775858 GTF3C4 essential 4.52661777432073e-09 1 0.000510111617838286 5.53242576098737 -3.16723621135409 1.8241482292142e-17 66.2564851497903 10.9243211445788 6.06504370138095 2.46797577655383e-09 -107.090350233224 25.0312680129259 -4.27826309789515 2.22485653802943e-05 DDX31 other 2.02881766053203e-13 0.262822302837416 2.70243347532645e-05 6.06504370138095 -4.27826309789515 4.25365669093776e-10 172.546880681803 29.6472477185949 5.81999659191231 1.00888382966668e-08 -281.140045095838 113.138935514252 -2.48490976000409 0.0132596209478576 PPP1R12C other 3.55478089661668e-06 1 0.000107970747450928 5.81999659191231 -2.48490976000409 7.87253244054507e-20 955.519769451669 98.3121531518681 9.71924364199028 1.17206362708831e-20 237.675530756111 408.487832528063 0.58184237529225 0.560920252865667 MBOAT7 other 9.2911627863313e-16 1 1.62166723443939e-16 9.71924364199028 0.58184237529225 9.46083927965771e-07 14.9822022629222 2.97066471074626 5.04338379512324 6.36388590742726e-07 -23.5349007532619 21.1666178051401 -1.11188764165934 0.266709299545189 SRMS other 0.00633308581380287 1 0.00619651570806192 5.04338379512324 -1.11188764165934 0.00086686778519941 16.1453724259359 4.34785419565729 3.71341165075456 0.000227545843874143 30.6495008410917 26.4126451433901 1.16041012457103 0.246436732042824 OPRL1 other 1 1 1 3.71341165075456 1.16041012457103 2.52487647385235e-36 613.750090019647 44.7046620538778 13.7289951835439 1.02384135658443e-36 -211.58488595796 347.646870302956 -0.60862013736403 0.543047759586143 SLC2A4RG other 3.63178231998921e-32 1 1.5358644190123e-32 13.7289951835439 -0.60862013736403 6.6469609322086e-26 10.1030355635163 0.886561917775029 11.3957472805413 5.80642897897818e-27 5.57442883034595 6.31694220025996 0.882456836492274 0.377944736915064 FNDC11 other 8.70419534072716e-22 1 8.4094510902541e-23 11.3957472805413 0.882456836492274 2.90611894135723e-26 1947.45779301415 175.036076193094 11.1260366169645 6.59475293626723e-26 -1862.9122011975 1251.92221604522 -1.48804149117377 0.137354369598774 PPDPF other 3.82038396030822e-22 1 9.49380632705031e-22 11.1260366169645 -1.48804149117377 0.577780238429913 10.5654628767321 10.1503275963127 1.04089870760134 0.298384094210149 2.73104019796978 26.758009213153 0.102064401585875 0.918743096978566 IL1B other 1 1 1 1.04089870760134 0.102064401585875 0.808248509570334 0.175230481837495 1.925484965064 0.0910058946275235 0.927522552487783 -4.73470198074468 7.61425766366911 -0.621820562145667 0.534329279891735 PLGLB2 other 1 1 1 0.0910058946275235 -0.621820562145667 0.000261785561607861 10.3702809541072 27.656637873314 0.374965351956736 0.707832104666144 -285.346438298117 73.1142325805418 -3.90274818221996 0.000107014270897817 CHCHD5 other 1 1 1 0.374965351956736 -3.90274818221996 0.704727255319935 4.7373582014983 7.45105524767416 0.635796950100063 0.525176149882594 13.3747871768276 19.8924678414265 0.672354344541119 0.501643605866385 PAX8 other 1 1 1 0.635796950100063 0.672354344541119 5.99516316891071e-05 79.4371852987093 31.3233177970759 2.53603994996101 0.0114915830189307 -220.822297534247 77.0386812464773 -2.86638210781086 0.00431358269001316 INSIG2 other 0.335609234195621 1 1 2.53603994996101 -2.86638210781086 1.00729918994227e-05 97.5601831549956 26.279472903166 3.71241019614371 0.00022640760581469 -156.929568949701 69.4735022650779 -2.25884062028329 0.0242876843440812 POLR1B essential 0.0612538637403892 1 1 3.71241019614371 -2.25884062028329 0.0127324384472482 43.3370914143025 28.0086733154682 1.54727397924874 0.122379788333401 -139.502145407381 68.4430772089352 -2.03822141107894 0.0420118038427655 CCDC93 other 1 1 1 1.54727397924874 -2.03822141107894 9.11307736908908e-08 -26.3218552812737 69.2032723556352 -0.380355644831445 0.703829627810057 -1054.33560379597 184.723726459505 -5.7076349855204 1.88289574776034e-08 PSD4 other 0.000660606978485268 0.000255132373821526 1 -0.380355644831445 -5.7076349855204 2.11625398607211e-18 180.73087306125 38.584743972905 4.68399824521742 3.55664995494173e-06 -546.816442183123 91.9243546315971 -5.94854806840456 4.84017848850703e-09 SLC25A23 other 2.41397457386405e-14 6.67605818919774e-05 0.0330590613311834 4.68399824521742 -5.94854806840456 1.10497530654527e-26 4.75409219258718 2.58904965674658 1.83623059534563 0.0668680840785848 -62.1037453923592 6.17720647758051 -10.0536942739016 6.27770769941443e-22 PSPN other 1.46044586266089e-22 9.72228591408313e-18 1 1.83623059534563 -10.0536942739016 5.66825062394469e-35 172.573691251502 43.1003592885378 4.00399658147156 7.0915773731448e-05 -1100.84882397317 102.833029057373 -10.7052066253827 2.1071799615561e-24 GTF2F1 other 8.08519268999471e-31 3.27813986619282e-20 0.593777773453414 4.00399658147156 -10.7052066253827 1.68642413764615e-09 150.449420308598 41.9553789329425 3.58593877912679 0.000366052800690273 -380.380478790682 100.101223566175 -3.79995833456742 0.000161027529200734 ALKBH7 other 1.36516033942456e-05 1 1 3.58593877912679 -3.79995833456742 9.14772662318042e-22 257.598952391599 31.7851936094263 8.10436946072921 3.50778595779382e-15 -236.684407564876 75.8362062866054 -3.12099482759438 0.0018979055008478 CLPP other 1.12187719306685e-17 1 4.49943704806214e-11 8.10436946072921 -3.12099482759438 0.0665261681066839 6.48391552910852 2.96809327078148 2.18453900790029 0.0293464227077728 -0.589968647684555 7.94846346991255 -0.0742242384226553 0.940859094482092 TNFSF9 other 1 1 1 2.18453900790029 -0.0742242384226553 5.03088035785763e-165 617.769080286866 14.9724072746015 41.2605046708034 1.75914166232482e-164 -81.1526711150767 173.144991797765 -0.468697767532679 0.639486346799003 MED1 essential 7.88288643272711e-161 1 2.75639907069675e-160 41.2605046708034 -0.468697767532679 4.03718537842195e-121 4786.15460328208 155.182251887909 30.8421520183843 5.23236687268815e-119 -2091.07385064787 1158.85250711277 -1.80443485069354 0.0717483740125012 RPL23 essential 6.31779139869251e-117 1 8.18760768238241e-115 30.8421520183843 -1.80443485069354 1.77367680148548e-08 28.7042915501849 8.20738936995931 3.49737172885307 0.000508500449509715 -61.3999339854706 17.5312869551511 -3.50230614230119 0.000499380911612069 ATG4C other 0.000135225119345253 1 1 3.49737172885307 -3.50230614230119 0.255454705243447 0.807106643245142 1.22163268709563 0.660678657153482 0.509096551061992 5.39297189497516 3.27149516580863 1.64847313587338 0.0998298135650304 CD70 other 1 1 1 0.660678657153482 1.64847313587338 0.772983531784215 -464.017798561293 647.038930303627 -0.717140463779436 0.473593539427239 -353.522072652301 1743.27021149053 -0.20279247033656 0.839372650998706 C3 other 1 1 1 -0.717140463779436 -0.20279247033656 1.0201583180136e-17 61.8567402555717 12.5697709474688 4.92107139534057 1.14077305180427e-06 -195.396386930084 34.1472351082504 -5.7221730049492 1.73393757474852e-08 SH2D3A other 1.14298537950244e-13 0.000235191292638889 0.0109411543398548 4.92107139534057 -5.7221730049492 7.70206768618716e-12 143.832370974588 26.3995700503195 5.44828460086408 7.70002098744025e-08 -206.158899819371 71.3084564781881 -2.89108627505394 0.00399168428992204 TRIP10 other 7.02197510949683e-08 1 0.000792101158977978 5.44828460086408 -2.89108627505394 0.375223759164542 -0.607840570744439 1.91170201097646 -0.317957802656684 0.750638292216087 6.12253666658745 5.15056051946975 1.1887126931998 0.235068545795577 TNFSF14 other 1 1 1 -0.317957802656684 1.1887126931998 0.227311218310624 -5.18384466557411 302.920015494272 -0.0171129156226791 0.986352775190631 -1478.83215443792 906.604540490945 -1.63117664691719 0.103428631159805 FOSB other 1 1 1 -0.0171129156226791 -1.63117664691719 5.12732671045288e-16 48.3983200888601 12.5649208602518 3.8518603202639 0.000131105113311879 -227.262936812165 37.6053536252017 -6.0433665662929 2.79374572664021e-09 OPA3 other 5.46726847135591e-12 3.87436657370465e-05 1 3.8518603202639 -6.0433665662929 9.89508109932463e-12 587.054402009826 90.8557819870784 6.46138736765611 2.29667381403309e-10 -281.337358867558 273.704557985869 -1.02788700684365 0.304457288018155 SNRPD2 essential 8.96989101653778e-08 1 2.61568180680229e-06 6.46138736765611 -1.02788700684365 0.00509285674027034 21.8551795172656 25.3294898334839 0.862835361507142 0.388606129271352 -203.409401872795 75.8082309413785 -2.68320998059022 0.00751263901413796 RTN2 other 1 1 1 0.862835361507142 -2.68320998059022 5.5347086591897e-10 324.833477325089 59.1940297913838 5.48760539652212 6.23986358214749e-08 -306.827648394683 177.160878891608 -1.73191536593363 0.0838523837803511 VASP other 4.59934289578664e-06 1 0.000645014698486587 5.48760539652212 -1.73191536593363 1.18911955558588e-18 378.251707508574 53.828446915918 7.02698534288788 6.30444291989299e-12 -580.535313925665 161.215501239748 -3.60098941765119 0.000345855678147404 SYMPK essential 1.3630877465681e-14 1 7.51804818197239e-08 7.02698534288788 -3.60098941765119 0.000119142244290034 79.0366896310342 32.1529893151027 2.45814436898748 0.0142746323846436 -376.091084807408 133.552965831394 -2.81604442451851 0.00503732981908018 GPCPD1 other 0.641461843257545 1 1 2.45814436898748 -2.81604442451851 0.286665804955536 11.055840926261 7.04386677510229 1.56956985122713 0.117094528616351 6.86770667976529 25.8628762233041 0.265543036299151 0.790691391170803 SDCBP2 other 1 1 1 1.56956985122713 0.265543036299151 7.46897553741343e-27 140.010642237774 14.9771494548212 9.34828370779891 2.28057744610258e-19 -245.075558998792 59.0376093812321 -4.15117687805125 3.8378735171124e-05 PANK2 other 9.89340499685783e-23 0.445884145218119 3.11595296460995e-15 9.34828370779891 -4.15117687805125 0.0590814900393529 5.92890099064254 4.05606715420298 1.46173639765774 0.144386641005545 -21.4001771223768 15.2238414352037 -1.4057015250363 0.16037947404197 TGM3 other 1 1 1 1.46173639765774 -1.4057015250363 0.00500299404617429 -234.105734398456 73.1400981873071 -3.20078507139717 0.00145188452080306 -429.356966168257 295.417908372717 -1.45338841688147 0.146702249756651 CD93 other 1 1 1 -3.20078507139717 -1.45338841688147 4.1700702405931e-12 69.8304663688251 12.686511400095 5.5043080139669 5.76717525681992e-08 -180.006896633877 51.645105008211 -3.48545901117362 0.000531775960004076 GZF1 other 3.84563877587496e-08 1 0.000597133326091134 5.5043080139669 -3.48545901117362 0.947652518382458 -1.59513818264884 6.13548818407166 -0.259985535754103 0.79497366158949 -6.77384107292948 26.0854754073946 -0.259678651323689 0.795210268955653 PAX1 other 1 1 1 -0.259985535754103 -0.259678651323689 0.0641620372608326 24.969000955687 24.4666555944787 1.0205318360439 0.307940149732301 -179.565969664689 99.5773025212817 -1.80328212472227 0.0719095846684045 NAPB other 1 1 1 1.0205318360439 -1.80328212472227 2.85897851600613e-16 334.407161249629 55.407468856516 6.03541667127251 2.95793408709130e-09 -1032.13324058423 225.759782527038 -4.57182067164961 6.00688654499826e-06 CENPB other 3.07397370040979e-12 0.0734822431049637 3.22976822969499e-05 6.03541667127251 -4.57182067164961 6.52389429574081e-39 453.618498854076 42.8527763853342 10.5855101376657 6.05553337704213e-24 -989.428924016218 158.157410839207 -6.25597573181148 7.98507400738366e-10 PSMF1 other 9.50857593604222e-35 1.12110439063667e-05 8.61884065554407e-20 10.5855101376657 -6.25597573181148 0.16646106323325 10.1092954670748 5.33459240135131 1.89504552672366 0.0586192264127456 12.858679052059 22.8877826371798 0.561814102130228 0.574475352525882 NKX2-2 other 1 1 1 1.89504552672366 0.561814102130228 2.9255538477661e-93 396.530253906734 15.7054311550345 25.2479699533511 1.26968778146734e-93 152.043778985844 96.290427691453 1.57901239646627 0.11491554582045 DTD1 other 4.56503422405422e-89 1 1.98236353320496e-89 25.2479699533511 1.57901239646627 6.57139041529264e-20 301.134486395056 44.9687881371986 6.69652216280107 5.37495358125359e-11 -819.966431109538 166.607779734547 -4.92153747211551 1.14280919348279e-06 RBCK1 other 7.76804060991743e-16 0.0144725356262661 6.23494615425416e-07 6.69652216280107 -4.92153747211551 0.0145617665740536 211.16141772924 91.6482024640266 2.30404320054312 0.0215982486137051 -397.152788004094 350.016186913509 -1.13466977486453 0.257016190653739 TMX4 other 1 1 1 2.30404320054312 -1.13466977486453 1.20568130076669e-27 298.52076512523 28.5308072007231 10.4631026744194 1.75569902628231e-23 -249.802757100431 107.086117741442 -2.33272773697498 0.0200234992531208 STK35 other 1.61151362660476e-23 1 2.48923007946306e-19 10.4631026744194 -2.33272773697498 2.20846326409071e-18 943.245098706533 107.570638228474 8.76861115858711 2.27948377529605e-17 -268.572370276809 400.406488768017 -0.670749295555026 0.502662844159594 SNRPB essential 2.51764812106341e-14 1 3.03558854356175e-13 8.76861115858711 -0.670749295555026 8.46797119861306e-20 233.639053514834 33.5930501832184 6.95498182631686 1.02488990211286e-11 -568.178680159989 124.46107038645 -4.56511163206135 6.18995139841118e-06 NRSN2 other 9.99135921724355e-16 0.0756535859913815 1.21603186885691e-07 6.95498182631686 -4.56511163206135 4.68101434399636e-33 64.2749979918466 6.10108703307921 10.5350075557613 9.46620008147886e-24 -116.380803878712 24.6002976547274 -4.73086974442959 2.85061764601203e-06 AP5S1 other 6.58478287769969e-29 0.0354531316634516 1.34495770757652e-19 10.5350075557613 -4.73086974442959 4.16545671836744e-19 1285.13655742619 139.831121908362 9.19063324306586 8.69865610028331e-19 -784.717994040953 868.002021214572 -0.904050883364209 0.366376842618611 RRBP1 other 4.8327628846499e-15 1 1.18066859249145e-14 9.19063324306586 -0.904050883364209 0.320559179632813 8.52609240053979 8.14100536820194 1.04730214696111 0.295426192499014 41.9599009188728 31.8473830819668 1.31753057420382 0.188216472417147 BMP2 other 1 1 1 1.04730214696111 1.31753057420382 1.90054936439501e-49 103.221234830059 6.34918596307614 16.2573966852357 1.03019424142442e-48 -24.6261025646321 39.0429501363594 -0.630743898158931 0.528473365860284 ZNF133 other 2.86887926555427e-45 1 1.5770213447725e-44 16.2573966852357 -0.630743898158931 0.0987556555054507 12.5594161469257 27.2147150778538 0.461493574744278 0.644629683463455 -211.889630515698 110.734414252717 -1.91349393903982 0.0562113288711976 FLRT3 other 1 1 1 0.461493574744278 -1.91349393903982 1.94247899315396e-11 16.4574476410901 5.89163520793439 2.79335822063906 0.00540015142981189 -217.243217263268 36.2430432181618 -5.99406666696259 3.72890364937783e-09 OVOL2 other 1.73599347618169e-07 5.15520929526485e-05 1 2.79335822063906 -5.99406666696259 0.46214529589982 25.0517901337234 22.0489653066058 1.13618892248962 0.25637870143579 -36.5085950745571 133.382805500596 -0.27371290427981 0.784409342426574 PCSK2 other 1 1 1 1.13618892248962 -0.27371290427981 7.77386402713339e-33 156.678328089998 14.5005881275667 10.8049636822758 9.19905580990612e-25 -257.696559611628 56.8090738319347 -4.53618660240798 7.06876131266403e-06 MKKS other 1.09191694125116e-28 0.0861399253561239 1.31546498081657e-20 10.8049636822758 -4.53618660240798 4.9386044417223e-12 19.2187789540017 2.72708438173179 7.04737230822212 5.55579459136937e-12 -14.6387727189488 16.7696174206895 -0.872934209034977 0.38308479126997 BFSP1 other 4.54334693418364e-08 1 6.63584105993158e-08 7.04737230822212 -0.872934209034977 4.51530063522805e-45 2120.64615024762 151.881061847436 13.9625449312292 4.86692543858039e-38 -4245.2305727873 934.239685021134 -4.54404864281832 6.81682561908326e-06 DSTN other 6.74405302877661e-41 0.0831584557271967 7.32326270743192e-34 13.9625449312292 -4.54404864281832 1.12727749948039e-07 -57.7445975982013 16.905016328284 -3.41582619483118 0.000684012783085365 -357.565952719426 67.7408697211185 -5.27843758415687 1.89437551392479e-07 LAMP5 other 0.000812428893875515 0.00247443329628856 1 -3.41582619483118 -5.27843758415687 7.30908863365597e-105 529.049356207199 19.4131375374438 27.2521304290342 1.0510589778873e-103 19.0027342156907 117.437653527325 0.161811255972253 0.871514679122973 SNRPB2 other 1.14233746255409e-100 1 1.64312050013122e-99 27.2521304290342 0.161811255972253 1.09337773447534e-57 168.212442677138 9.40603824679712 17.883452976009 1.33174771214162e-56 -46.0391103052328 57.8622807860284 -0.795667050793987 0.42657262438058 MGME1 other 1.67516402698967e-53 1 2.05315544780874e-52 17.883452976009 -0.795667050793987 5.133131251912e-31 166.86268705948 22.0453049073379 7.56908048044006 1.63891528450039e-13 -611.701931924467 81.6770799554724 -7.48927278323303 2.84904539382067e-13 TBC1D20 other 7.09090751139124e-27 4.20946456937004e-09 2.03110771208134e-09 7.56908048044006 -7.48927278323303 1.28690036591939e-13 168.73009222576 25.9488921138083 6.50240062218196 1.79700655288836e-10 -263.940635772248 101.707313470767 -2.59509986809463 0.00971249326148624 ITPA other 1.26180580878396e-09 1 2.05451759191726e-06 6.50240062218196 -2.59509986809463 6.02821078315917e-05 4.24874900284284 1.60756434619312 2.64297290052764 0.00845722960708949 24.9395762772211 5.95596940888207 4.18732444126208 3.29672819473747e-05 TCF15 other 0.337338675425587 0.384530376634178 1 2.64297290052764 4.18732444126208 3.60830682799114e-13 112.005194968422 14.6292504704863 7.65624973025011 8.72722048065367e-14 35.6072571499844 59.6089775352212 0.597347222219088 0.550522769158014 MCM8 other 3.47155199921028e-09 1 1.0881098495279e-09 7.65624973025011 0.597347222219088 0.0665914885296227 10.2991882366282 4.48647937642384 2.29560583533489 0.0220765632188755 4.45119941892861 16.558319479191 0.268819515441919 0.788170118458337 TMEM74B other 1 1 1 2.29560583533489 0.268819515441919 9.91891777621629e-15 167.865983019924 27.483573552956 6.10786594750773 1.92148668170298e-09 -364.060854149177 101.301939132938 -3.5938192029219 0.000355402170590026 FAM110A other 1.01311826166273e-10 1 2.11363534987328e-05 6.10786594750773 -3.5938192029219 1.06431986629822e-13 211.560801907107 31.7068539670146 6.6723996687656 6.19855593728511e-11 -294.062305154997 124.366252576193 -2.36448633824389 0.0184046413158957 MRPS26 essential 1.04601356459789e-09 1 7.18040719775108e-07 6.6723996687656 -2.36448633824389 0.806588945408827 -2.05437499394517 3.15416975541115 -0.651320364232385 0.515114237676605 -1.38735084880956 6.35791390322918 -0.218208498876483 0.827348343183584 S1PR4 other 1 1 1 -0.651320364232385 -0.218208498876483 6.90740065618615e-13 268.940692726757 51.4756832770582 5.22461627715041 2.4886064051366e-07 -289.513314503913 104.491714597794 -2.77068201644788 0.00578483888072317 NCLN other 6.5641028435737e-09 1 0.00248586893809095 5.22461627715041 -2.77068201644788 2.4285315249733e-07 233.939253110538 103.672680879603 2.25651783213956 0.0244335820915607 -525.509327340334 165.150589206125 -3.18200092331758 0.00154594113786313 HNRNPR other 0.00170677195575124 1 1 2.25651783213956 -3.18200092331758 2.14164457576829e-10 -37.8136645283049 45.7308648074696 -0.826874031083893 0.408670333865529 -448.277499328216 72.386484882068 -6.19283420183408 1.16434830362095e-09 ZNF436 other 1.82125454723335e-06 1.62869040710498e-05 1 -0.826874031083893 -6.19283420183408 1.04934354973045e-31 138.511107146966 34.9877428293542 3.95884661158414 8.54473188839382e-05 -650.70804246704 69.4925583352012 -9.3637082596429 2.10154716692055e-19 MAX other 1.4586924684803e-27 3.22923737669012e-15 0.71057990383883 3.95884661158414 -9.3637082596429 3.68186093978291e-51 95.4365390809621 13.3761324887096 7.1348380528914 3.15386825353274e-12 -293.484902573339 26.5676374667748 -11.0467068417494 1.0509814024281e-25 CHURC1-FNTB other 5.58096481252294e-47 1.63816471196468e-21 3.790634253921e-08 7.1348380528914 -11.0467068417494 0.00656318592337725 13.9819923057798 5.93593213592638 2.35548385419634 0.0188633889007557 83.3461589376827 33.2773083457641 2.50459436417405 0.0125594864548239 GDF5 other 1 1 1 2.35548385419634 2.50459436417405 7.12810871870893e-39 137.49864468941 9.70181793455649 14.172461864045 6.08856350873434e-39 -67.4858052016416 77.8298305610542 -0.86709433536158 0.386279051401438 MMP24 other 1.0384941592287e-34 1 9.1858157656275e-35 14.172461864045 -0.86709433536158 5.83092767484736e-07 188.675146698858 42.8278885400652 4.40542723749628 1.28035041140952e-05 -598.798978321918 246.01233170158 -2.43402017362397 0.0152645625302567 NECAB3 other 0.00397261102487351 1 0.114360898747098 4.40542723749628 -2.43402017362397 0.956550776327468 -5.66054421423155 19.2720001417825 -0.29371856437253 0.769089711295885 1.94338805613809 113.628786672692 0.0171029552725579 0.986361016206462 ID1 other 1 1 1 -0.29371856437253 0.0171029552725579 1.98087955276613e-17 680.70797183228 77.1899309549749 8.81861096921227 1.7033939002767e-17 -305.139322955545 431.53578018686 -0.70710086385749 0.479816936531067 RALY other 2.20075718312317e-13 1 2.2728384811392e-13 8.81861096921227 -0.70710086385749 2.93902972957443e-17 483.964018703908 57.5504028373755 8.40939411095839 3.90964282795513e-16 -610.087902186947 318.732254259913 -1.91410782571583 0.0561497280406025 DYNLRB1 essential 3.25291810469298e-13 1 5.10012906906747e-12 8.40939411095839 -1.91410782571583 4.59096889430834e-27 361.600156056613 31.2495071809206 11.5713874770284 9.46632159840184e-28 76.4613480457082 171.595366221781 0.44559098377333 0.656075713929529 EIF2S2 essential 6.09660919184332e-23 1 1.37725512935148e-23 11.5713874770284 0.44559098377333 1.14387199813407e-20 828.013398044933 89.929163628857 9.20739573940878 7.80976800868873e-19 -1192.41584801736 504.150054081963 -2.36520027789881 0.0183808488241667 ERGIC3 other 1.37207446176182e-16 1 1.06048839789984e-14 9.20739573940878 -2.36520027789881 5.56175008129782e-07 221.703812603873 41.0496242828066 5.40087312557285 1.00518882299243e-07 57.7186957914558 221.402407959118 0.260695880968528 0.794428876831348 ROMO1 essential 0.00379366973045324 1 0.00102629778827527 5.40087312557285 0.260695880968528 0.651196651744133 203.549797549388 264.86234292399 0.768511655157422 0.442517989439319 -622.362087380307 1552.53981055653 -0.400867071587178 0.688675970129959 BPIFB1 other 1 1 1 0.768511655157422 -0.400867071587178 5.35713912867988e-20 249.328861654924 26.9787350746091 9.24168093742761 5.92918449754007e-19 -268.979776336793 151.244937660719 -1.77843821087211 0.0759072472680638 CEP250 other 6.34231701444411e-16 1 8.05894756905646e-15 9.24168093742761 -1.77843821087211 1.77545718564166e-12 106.377634723064 14.9621515041363 7.10978195172372 3.74692135049002e-12 -131.167356182458 85.9861910852791 -1.52544675519316 0.127739726172299 PLAGL2 other 1.66218301719772e-08 1 4.49668031272307e-08 7.10978195172372 -1.52544675519316 3.49663869014937e-34 55.5600862357354 36.0138827247558 1.54274079971787 0.123496198276457 -723.7794695083 66.2218216676774 -10.9296218569833 3.40852950708483e-25 TMEM115 other 4.95963231810787e-30 5.30810300138321e-21 1 1.54274079971787 -10.9296218569833 5.03464155571977e-17 688.2153903475 93.1993110564531 7.38433988992291 5.89492684531823e-13 -319.417859705369 178.663049995416 -1.78782271831565 0.0743694164147394 PSMB2 essential 5.53407799804717e-13 1 7.20183212692528e-09 7.38433988992291 -1.78782271831565 5.57379749640411e-13 89.4234296436362 20.9341821413957 4.27164668003956 2.29593845486085e-05 -178.34653532793 41.038063329986 -4.3458808934001 1.6600169256642e-05 AGO3 other 5.31405853307168e-09 0.197923818046943 0.201009411723067 4.27164668003956 -4.3458808934001 3.41997781137945e-11 75.4217307552635 36.0935853535234 2.08961592528244 0.0371153678106574 -447.373651613499 77.7628210348833 -5.75305326709808 1.46270018294283e-08 UROD essential 3.02086640079147e-07 0.000198985732887543 1 2.08961592528244 -5.75305326709808 6.89920161364029e-12 33.8384321152673 9.88303635955448 3.42389027867471 0.000664013078860591 -110.286894307225 21.9507489925312 -5.02428843520331 6.87235498666961e-07 ST3GAL3 other 6.30587027486723e-08 0.00879111649894776 1 3.42389027867471 -5.02428843520331 5.79247571357104e-20 47.0334033000846 11.1992788134447 4.19968143338135 3.12198188358391e-05 -172.009392792256 24.5987644008258 -6.99260296124797 7.92835602100706e-12 TMEM53 other 6.85481575943997e-16 1.15286224901464e-07 0.27048851039371 4.19968143338135 -6.99260296124797 4.58238590784481e-14 121.928774002839 35.3738150943387 3.4468652498371 0.000610980258633571 -441.696302734026 76.1721396496617 -5.79865951994414 1.13424705453636e-08 HECTD3 other 4.56268164844107e-10 0.000154722640709305 1 3.4468652498371 -5.79865951994414 5.93729105994926e-18 303.551621063032 47.042254031 6.4527439706226 2.4352605626727e-10 -340.734128952351 97.5193500982411 -3.4940155836672 0.000514644663889582 KLC1 other 6.69429567009279e-14 1 2.77181357243406e-06 6.4527439706226 -3.4940155836672 6.22353108194343e-09 67.3593253704104 14.2321718099753 4.73289152701193 2.82717123291336e-06 -54.9883293653383 29.5035213338351 -1.86378868959878 0.0628908861102995 XRCC3 essential 4.87738130891907e-05 1 0.026462322740069 4.73289152701193 -1.86378868959878 7.96281233153271e-78 313.446513856603 14.1411822218148 22.1655098520027 3.70225502160978e-78 117.404504518288 40.7704082990396 2.87964995732096 0.0041370820029655 TUBGCP3 essential 1.2375006644435e-73 1 5.76181949013131e-74 22.1655098520027 2.87964995732096 2.0905695739522e-17 178.783673481831 39.7614584371106 4.49640633189064 8.44567267099557e-06 -738.484232051275 113.951994283232 -6.48066088440492 2.04290700763606e-10 MCF2L other 2.32095034100173e-13 2.90440089275619e-06 0.0765600227625748 4.49640633189064 -6.48066088440492 0.307657034305887 -3.10225894059263 4.61433425414892 -0.672309106736963 0.501672376228973 -19.9298416717675 13.2227153217577 -1.50724273999709 0.132328921197768 F10 other 1 1 1 -0.672309106736963 -1.50724273999709 8.38602730104916e-53 240.213756779489 14.9356656960687 16.0832306820256 6.9438765081813e-48 -98.5462882248328 42.8321964571234 -2.30075262013428 0.0217836542943409 PCID2 essential 1.27501159085151e-48 1 1.06164927933584e-43 16.0832306820256 -2.30075262013428 0.0855877272282084 2.56427879632952 1.45996244408513 1.75640052024516 0.0796008306973392 16.4597701954882 10.5391569432474 1.56177294674734 0.118941764320241 SLURP1 other 1 1 1 1.75640052024516 1.56177294674734 8.03167001102381e-22 97.9861936011094 9.74134978463576 10.058790184873 6.09460630016739e-22 -10.3005050313101 44.9455344475286 -0.229177495782932 0.818817255653097 LRFN3 other 9.86208760653614e-18 1 8.52269745015408e-18 10.058790184873 -0.229177495782932 0.0248844881664739 11.5463060801081 6.35997108869394 1.8154651835814 0.0700018902050484 -47.6183631573433 29.204143468748 -1.63053448933713 0.103566319861239 IGFLR1 other 1 1 1 1.8154651835814 -1.63053448933713 9.20683512170468e-18 1143.80320658446 143.350324961944 7.97907648195501 8.8586133197727e-15 -1842.10822986798 677.644997497385 -2.71839714993998 0.0067703866911347 CAPNS1 other 1.03328310570892e-13 1 1.12867592307224e-10 7.97907648195501 -2.71839714993998 1.28441465736627e-37 77.1266734783797 5.51876309251337 13.9753550180489 3.99530580950493e-38 32.8880330522514 24.25872071192 1.35572000860257 0.175752876655569 PDCD2L other 1.86034618972931e-33 1 6.01333477388586e-34 13.9753550180489 1.35572000860257 4.54148706314736e-19 335.537037171716 37.4125949331228 8.96855825615701 4.80931863996105e-18 -337.950096887478 202.019193390458 -1.67286133171662 0.0949284748348303 RBM42 essential 5.26176691136253e-15 1 6.46853357074761e-14 8.96855825615701 -1.67286133171662 1.42085299619019e-40 901.831858623528 62.7645519591167 14.3684903416655 6.88315736163646e-40 26.7421104828942 272.292043145917 0.098211134537499 0.921801017273719 UBA2 essential 2.08567011310758e-36 1 1.0401827404905e-35 14.3684903416655 0.098211134537499 0.137897798819304 21.9855650619204 11.6121478897804 1.8933245830661 0.0588422137581665 60.0315690469012 63.0406719645318 0.952267277237724 0.3413820358257 FFAR2 other 1 1 1 1.8933245830661 0.952267277237724 0.0434032673989016 -10.454419977391 6.37536089792162 -1.639816183708 0.101621484299873 -64.4723569964908 29.4208596621879 -2.19138249992578 0.0288474094667445 HCST other 1 1 1 -1.639816183708 -2.19138249992578 8.96821857928526e-27 963.777197449521 85.9525488851919 11.2128983951 2.12653520675011e-26 -409.810289628108 464.123502437606 -0.882976809999404 0.377638103348121 COX6B1 other 1.1869437289684e-22 1 3.07114214558852e-22 11.2128983951 -0.882976809999404 4.34242463275291e-62 113.124965941907 6.46012056674335 17.511277811791 3.62137511038097e-54 -625.233040279536 105.812162684003 -5.90889576793483 6.28155713432544e-09 THRA other 6.68646544951293e-58 8.63588474827061e-05 5.57184774483217e-50 17.511277811791 -5.90889576793483 0.268543139221314 -0.965543709171806 5.01203692287986 -0.192644971301811 0.847311661711561 29.9547489640075 20.1081162820764 1.48968449076993 0.136908847336064 CCR7 other 1 1 1 -0.192644971301811 1.48968449076993 6.58688345373617e-16 38.7569723441531 5.35011295257855 7.24414095322487 1.6053178736622e-12 -202.629329532321 58.5121041541007 -3.46303269146952 0.000578773089012053 NR1D1 other 7.00646792973916e-12 1 1.94403994500493e-08 7.24414095322487 -3.46303269146952 3.84576427917628e-09 99.9462061579633 34.2848711057171 2.91516937163859 0.00370914446332918 -368.65671682962 85.8572510942587 -4.29383321887267 2.09776543701331e-05 FRMD8 other 3.05238310838221e-05 0.248249561816155 1 2.91516937163859 -4.29383321887267 1.00928153759965e-08 628.239162487426 136.816974794557 4.59182176356979 5.49194607435956e-06 -636.007405669599 325.204965486826 -1.95571246803538 0.0510230303975629 PRDX5 other 7.80073700410771e-05 1 0.0504325408008439 4.59182176356979 -1.95571246803538 1.29157815796754e-06 70.3409507776948 13.3458735555428 5.27061420782613 1.96622934761181e-07 52.9800458505363 44.0320424312319 1.20321572485036 0.229418144292188 BCL2L12 other 0.00853862320232338 1 0.00197507737967606 5.27061420782613 1.20321572485036 5.04983582374829e-05 136.363297938401 32.7055824622089 4.16941964253252 3.55490911266611e-05 -55.8041070781051 107.360903641135 -0.519780527040237 0.603428765097888 IRF3 other 0.285214727325303 1 0.306148772782805 4.16941964253252 -0.519780527040237 3.92986968314947e-10 392.995955552971 58.7264986921772 6.69196979736373 5.50494727364361e-11 232.893767599283 193.756345097221 1.20199298496482 0.229891145951963 PRMT1 essential 3.28969391176442e-06 1 6.38298636378976e-07 6.69196979736373 1.20199298496482 0.136889262447008 20.1299978454031 27.5181005093476 0.731518435967815 0.464778114490451 -148.916511246972 92.6032990259242 -1.60811237626948 0.108391815519972 RRAS other 1 1 1 0.731518435967815 -1.60811237626948 1.08819917342613e-09 42.8380548798495 9.44875186367166 4.53372630564597 7.13776392722676e-06 -121.194476876917 34.6857218223116 -3.49407394482874 0.000514608087341036 PRRG2 other 8.88949904771808e-06 1 0.0649964783213269 4.53372630564597 -3.49407394482874 8.34080840563409e-12 271.039679095619 47.1022046380711 5.75428859812958 1.45662343118586e-08 -442.115219676326 154.619941695771 -2.85936739354248 0.00440835726180074 SCAF1 other 7.59263789164871e-08 1 0.000154984733078176 5.75428859812958 -2.85936739354248 5.83255102856385e-18 191.316964118639 32.2960616367234 5.9238481233605 5.62709081308998e-09 -655.295783981313 119.196887372336 -5.49759140886256 5.96467539086018e-08 PRR12 other 6.5767845398086e-14 0.000795270169863387 6.0845732961942e-05 5.9238481233605 -5.49759140886256 0.0112203749493192 3.08968614584424 1.53705266751385 2.01013680997786 0.0449219389479655 -4.54679817014112 3.61925374179602 -1.25628057453767 0.209566678476683 FLRT1 other 1 1 1 2.01013680997786 -1.25628057453767 2.88473301460504e-05 72.2965697677624 24.6343174952453 2.93479085757973 0.00348271908132483 -263.6876899458 93.1258432861522 -2.83152002323946 0.00480914163779823 ASL other 0.167631835478699 1 1 2.93479085757973 -2.83152002323946 1.27783706214789e-07 196.404570251271 42.0496771973956 4.67077474410279 3.81333367393782e-06 -348.748676836184 154.672855735547 -2.25475035795848 0.0245586707868865 SBDS other 0.000917870361740827 1 0.0353724831594472 4.67077474410279 -2.25475035795848 5.77380252853462e-05 58.5097381831269 53.994147609195 1.08363111140517 0.279012881980549 -429.598227338857 121.2735632523 -3.54238974940573 0.000430899747089473 STAT5A other 0.323737107774936 1 1 1.08363111140517 -3.54238974940573 8.6871620361284e-10 32.6196135748822 94.4110622901663 0.345506265723691 0.729849862447439 -1238.73758543252 210.208896627435 -5.89288848049095 6.72635710868444e-09 WNK4 other 7.13302874786503e-06 9.24134203162155e-05 1 0.345506265723691 -5.89288848049095 7.80132524670752e-69 426.68946670744 43.5502237325738 9.79764120909197 5.92722367214344e-21 -1237.75379504145 97.0892622608202 -12.7486167493616 1.09746994237963e-32 BECN1 other 1.20631892289838e-64 1.71896717074922e-28 8.22402284509902e-17 9.79764120909197 -12.7486167493616 1.41138346472648e-20 521.231007286421 54.6026877129388 9.54588554370573 4.61271308915654e-20 59.1195563197882 255.130960991928 0.231722391080786 0.816841258740783 TRAP1 other 1.68942600727759e-16 1 6.34893829591507e-16 9.54588554370573 0.231722391080786 0.00370869004176094 62.7321132975024 27.0075760627194 2.32275984900756 0.0205607065016752 -231.673940982249 135.216727744145 -1.71335266610369 0.0872184528452087 GLIS2 other 1 1 1 2.32275984900756 -1.71335266610369 2.03462540529465e-27 266.979562655881 42.1184694531172 6.3387764589371 4.87927946231249e-10 -361.307276017597 67.5721371050673 -5.34698607291056 1.32037329034463e-07 DNAJC8 essential 2.71357990304148e-23 0.00173813939940967 5.49650831429503e-06 6.3387764589371 -5.34698607291056 1.37379677960494e-13 74.6834556611953 44.8771099048744 1.66417703411608 0.0966582559436807 -400.191104998807 70.234239554616 -5.69794885708996 1.99718485434465e-08 AHDC1 other 1.34453490819936e-09 0.000270259054489918 1 1.66417703411608 -5.69794885708996 0.586665430535026 869.737525078442 1499.20514072659 0.580132432481469 0.562065959834899 -1000.90198730646 2345.10689603777 -0.42680441944781 0.669690953492179 IFI6 other 1 1 1 0.580132432481469 -0.42680441944781 4.03501798545954e-51 336.868689654621 21.9149007951952 15.3716730366618 2.37506014562152e-44 -306.903810291096 81.9913042918923 -3.74312633445257 0.000201652230216742 ZNF384 other 6.11587676056103e-47 1 3.61317899953402e-40 15.3716730366618 -3.74312633445257 4.58340253101171e-49 333.33614194372 24.7730080147432 13.4556183788961 8.00492317956734e-36 -453.532675852095 85.8742583300244 -5.28135770453025 1.858425631331e-07 EMG1 other 6.91314603752496e-45 0.00242933398527588 1.19865719690841e-31 13.4556183788961 -5.28135770453025 1.49461870501283e-37 133.089678628659 33.0465694630506 4.02733720295737 6.44168514886234e-05 -787.157486909988 70.8302862960922 -11.1132896402456 5.29428123286167e-26 PCNX4 other 2.16420788485857e-33 8.25484329827792e-22 0.541938971573788 4.02733720295737 -11.1132896402456 9.98124589918245e-34 28.2554843309929 14.7701756173741 1.91300936853832 0.0562754291647338 -376.799230666461 32.4036635929123 -11.6282910290699 4.76632879817371e-28 ATG14 other 1.41114854522641e-29 7.44691211426661e-24 1 1.91300936853832 -11.6282910290699 2.34626911280886e-15 550.165096122774 225.780076030298 2.43673005074614 0.0151427229401055 -3335.21797390575 494.800193740759 -6.74053489892765 4.0610990068561e-11 KTN1 other 2.44997420759501e-11 5.84270314116387e-07 1 2.43673005074614 -6.74053489892765 4.65999664466281e-07 249.540195719344 68.1057322048822 3.66401164249514 0.000272602331246386 -360.301111210535 146.513861372413 -2.45916057249158 0.0142364484520828 SIX1 other 0.00320001969588995 1 1 3.66401164249514 -2.45916057249158 4.50391679763101e-07 -50.6008383542571 15.1330490965691 -3.34373053515892 0.000883940746541178 -161.602138136303 30.3238560919355 -5.32920805475266 1.45123752394437e-07 RHOJ other 0.00309689319005108 0.00190779684897727 1 -3.34373053515892 -5.32920805475266 5.11305368458722e-12 114.349327459375 25.3531779522555 4.51025617674893 7.94568635065754e-06 395.476719627811 56.1180499637183 7.04722847432325 5.5827127221185e-12 DLGAP5 other 4.69838503076719e-08 8.13401243612666e-08 0.0721468320639705 4.51025617674893 7.04722847432325 2.15814069155306e-08 15.1566839202829 4.26342003288678 3.5550529395107 0.000410810588467243 -29.6497986117245 9.1395333917117 -3.24412607744426 0.00125044335234259 L3HYPDH other 0.000163673390047384 1 1 3.5550529395107 -3.24412607744426 1.23104229834913e-08 283.67659837016 128.411983536093 2.20911312603802 0.0275850344493325 -1098.73237138342 254.683205318724 -4.31411395976586 1.90524563626114e-05 HSPA2 other 9.46794631660316e-05 0.226038342286022 1 2.20911312603802 -4.31411395976586 2.20289980741847e-16 32.1400545099051 21.2436112883181 1.51292800803501 0.130881881964023 -306.135061145124 42.1330694104042 -7.26590930661055 1.30110430133526e-12 ZBTB1 other 2.37758976214675e-12 1.90924045177936e-08 1 1.51292800803501 -7.26590930661055 1.78777841539611e-26 73.3297139419015 11.7836780135828 6.22299029703425 9.75736823953233e-10 -169.413835269297 25.3119112712662 -6.69304792726631 5.45884734116479e-11 TRMT5 essential 2.35647072933362e-22 7.83726712771028e-07 1.08736111661348e-05 6.22299029703425 -6.69304792726631 6.85522921226186e-06 16.7457840866296 22.2053589179305 0.754132556403207 0.451097739339798 -183.75385451376 44.306486912516 -4.14733523956854 3.90499338565182e-05 SGPP1 other 0.0422556328643821 0.45344783194189 1 0.754132556403207 -4.14733523956854 5.38492651588491e-18 87.6440239841113 34.5681745824938 2.53539635930028 0.0115129876421172 -484.839204771503 68.7543310017309 -7.05176237929356 5.42921580284654e-12 PLEKHG3 other 6.0774280658277e-14 7.91199618948826e-08 1 2.53539635930028 -7.05176237929356 0.576079884108689 22.6053685033989 21.5452819049927 1.04920272582558 0.294549008884551 17.4273210725785 71.5088255718385 0.243708674184152 0.807547995640465 PZP other 1 1 1 1.04920272582558 0.243708674184152 7.24694051063731e-43 200.486292527888 22.3394229691756 8.97455107969992 5.36867569139902e-18 -390.094741878516 51.4179096498562 -7.58674836326424 1.55455673764255e-13 RHOT1 other 1.07428646129687e-38 2.3032312624912e-09 7.21764759951684e-14 8.97455107969992 -7.58674836326424 0.298028199331427 -17.5828124246905 11.3035778252958 -1.55550859174363 0.120435719247979 -19.8788497380449 27.5146308476174 -0.722482880040758 0.470323692182295 EVI2A other 1 1 1 -1.55550859174363 -0.722482880040758 2.58785978411151e-19 60.3410841416813 14.5278718049042 4.15347030535553 3.81649312976388e-05 -296.665116387843 43.138894215076 -6.87697544839166 1.72709211459591e-11 WDR60 other 3.01951479610131e-15 2.49875687139736e-07 0.327684100121527 4.15347030535553 -6.87697544839166 1.55759966567807e-05 508.282253614145 121.557796611405 4.18140397229326 3.37909366444598e-05 1007.02947244452 281.421806255007 3.5783633324136 0.000376806970125802 AIF1L other 0.0931288840108916 1 0.291615783241688 4.18140397229326 3.5783633324136 0.578402374568496 3.61091665109413 8.15208153382039 0.442944128577908 0.657983204486518 -13.829025510901 18.8262759413063 -0.734559801100071 0.462925890247147 FAM78A other 1 1 1 0.442944128577908 -0.734559801100071 4.74721792791867e-23 253.040580340416 37.6113575072396 6.72777046911189 4.39637320543276e-11 -468.310237983601 87.0750907013157 -5.37823428275252 1.12110123142272e-07 NUP214 essential 5.95491016878118e-19 0.00148108683683256 5.1129820379183e-07 6.72777046911189 -5.37823428275252 1.35067429653181e-13 207.671268343784 53.877506363718 3.85450779666435 0.000129784376060217 -650.870975975268 130.70298581708 -4.97977128759834 8.55636967537261e-07 MAP2K2 other 1.32217506887499e-09 0.0108991036924896 1 3.85450779666435 -4.97977128759834 9.73640979397495e-18 3939.23846952308 522.247635063069 7.54285554408946 1.95171188867584e-13 -3591.21392760773 1395.61167795912 -2.57321859964612 0.010340521045106 CANX other 1.09164626610047e-13 1 2.41465794866975e-09 7.54285554408946 -2.57321859964612 0.00177827618232993 -2.35758460647884 0.738522086773049 -3.1923007432049 0.00149566513350365 -9.64571595489516 5.21112708247056 -1.85098459550946 0.0647310899142425 RGS13 other 1 1 1 -3.1923007432049 -1.85098459550946 9.63397661992061e-15 61.8763603644722 23.3153421423661 2.65389030050034 0.00819016433357794 -331.968208009948 50.9182701841462 -6.51962855001522 1.61331703200413e-10 IPPK other 9.84785090088285e-11 2.29671812676107e-06 1 2.65389030050034 -6.51962855001522 7.29182290888051e-14 7.15808933045851 5.18447721318353 1.3806771707389 0.167947319397087 -79.0103556311122 11.3143330427818 -6.98320929146756 8.4780538367065e-12 ZNF484 other 7.21380040375549e-10 1.23203078355019e-07 1 1.3806771707389 -6.98320929146756 0.00149768217207251 -70.2956040797867 27.5639376354559 -2.55027438421441 0.0110377432208906 -196.607632476855 59.9827249963541 -3.27773759009458 0.00111347354807879 OMD other 1 1 1 -2.55027438421441 -3.27773759009458 1.53491357650134e-05 -325.272044539338 155.038717568055 -2.09800525727748 0.0363679131034155 -1579.89262784762 334.568504325361 -4.72217978507388 2.97664565272602e-06 FGD3 other 0.0918492284178401 0.036981845589468 1 -2.09800525727748 -4.72217978507388 1.9498188050028e-08 -62.8891109802683 30.4423760853025 -2.0658410764011 0.0393225829571945 -420.986299966586 69.5332839288452 -6.05445732143746 2.6483260668187e-09 HIVEP3 other 0.000148342214684613 3.67508208292431e-05 1 -2.0658410764011 -6.05445732143746 1.12753755709842e-20 257.517173069945 35.6676741929008 7.21990370544544 1.78037090745595e-12 -374.63936765654 85.5211732652709 -4.38066216063802 1.42225360675394e-05 PPCS other 1.35270680725097e-16 0.170115753903838 2.15424879802169e-08 7.21990370544544 -4.38066216063802 0.0345002464689873 43.8373332990703 22.3604701034 1.96048352724055 0.0504539568192319 -52.567114772352 50.633624890425 -1.03818588706835 0.299649024550077 EDN2 other 1 1 1 1.96048352724055 -1.03818588706835 0.138209298692615 19.9697259901269 13.9054214539793 1.43611080442385 0.151547716195891 52.2419488390725 28.5223694108061 1.8316132186157 0.0675577316839758 BCL11B og 1 1 1 1.43611080442385 1.8316132186157 2.87845379230158e-07 135.904920765401 26.1045947676554 5.20616856821665 2.8003244567546e-07 -11.4078047221081 60.6284140589814 -0.188159378719856 0.850826557265142 TRAF2 other 0.00201088781930188 1 0.0027888431264819 5.20616856821665 -0.188159378719856 7.80095153606469e-22 98.1019952603432 10.7420060353456 9.13255819607133 1.30975883509436e-18 -84.9586128871838 38.0128885576899 -2.23499492174206 0.0258228282811254 ABHD8 other 9.58346896205548e-18 1 1.77367541448479e-14 9.13255819607133 -2.23499492174206 0.984172376891937 -0.30418070603009 4.15323994079684 -0.0732393770564892 0.941642802371368 2.81247106315356 17.4447440697718 0.16122168671004 0.871979211451386 MASP1 other 1 1 1 -0.0732393770564892 0.16122168671004 0.0498429117968074 35.1832254826865 18.7030311256619 1.88115098810976 0.0604842197302015 -134.445722181136 83.5717714718193 -1.60874563041267 0.108251055231359 ATP13A4 other 1 1 1 1.88115098810976 -1.60874563041267 1.24844765231955e-09 23.2923122319109 3.72499709855884 6.25297459719432 8.15982673214971e-10 29.1540482246065 16.5907378604008 1.75724844005837 0.079438988753877 HRASLS other 1.01661092328381e-05 1 9.11371047713801e-06 6.25297459719432 1.75724844005837 0.00212352836195527 31.1532689041727 8.90134113872281 3.49983990262424 0.000505197240771601 35.8571777046074 32.0130885234787 1.12007867276878 0.26319335261469 HELB other 1 1 1 3.49983990262424 1.12007867276878 1.68346587011839e-27 237.83272833013 21.1498914979343 11.2451039454911 1.98012255686075e-26 -231.953525448511 104.51583438765 -2.21931467903892 0.0268927751738626 RAP1B other 2.24759528319506e-23 1 2.86068305789672e-22 11.2451039454911 -2.21931467903892 0.0582956525909932 76.2759534946388 33.6480096983329 2.26687861120112 0.0237982124459088 -121.357099396241 237.228950940184 -0.511561084409299 0.609170486100887 TSPAN8 other 1 1 1 2.26687861120112 -0.511561084409299 1.1297227139051e-52 252.968108508499 14.6961570786831 17.2132147985429 4.69810132538717e-53 -109.426352366155 116.743339914899 -0.937324154387933 0.349019568730555 RAB3IP other 1.71683960832158e-48 1 7.22286097765023e-49 17.2132147985429 -0.937324154387933 0.0191290002973025 8.89665317987796 17.281397065595 0.514810992775002 0.606898918038284 -335.634049813345 124.188449170191 -2.70261889939043 0.0070993683979733 PTPRB other 1 1 1 0.514810992775002 -2.70261889939043 1.19838885250443e-07 105.041995017766 21.8021871097674 4.81795677144274 1.89905531193303e-06 351.882319703719 95.1107137600297 3.69971274310421 0.000238519296326971 DYRK2 other 0.000862120940491685 1 0.0179650632508865 4.81795677144274 3.69971274310421 1.62127164548561e-92 264.00463922262 10.3870149382549 25.4167959507119 2.10856644056725e-93 31.6492796362263 62.5156001373094 0.50626211004472 0.612885993794075 YEATS4 essential 2.5293458941221e-88 1 3.29168307036954e-89 25.4167959507119 0.50626211004472 1.77067603598122e-13 82.2397794848461 15.3029283381373 5.37412040804579 1.14243793148895e-07 -171.955458811696 47.2839987979466 -3.63665221180835 0.000302416909915711 LRRC61 other 1.7255237970637e-09 1 0.00116197362011742 5.37412040804579 -3.63665221180835 1.16970827932776e-12 62.7941554162911 21.0573962078962 2.98204748565943 0.00299912845381929 -234.456896914891 47.3780913816899 -4.94863533074912 1.01454006221319e-06 IDUA other 1.10233308243849e-08 0.0128765424696098 1 2.98204748565943 -4.94863533074912 5.60997939144793e-08 250.543938504097 42.6740820129693 5.8711031775201 7.65852664613103e-09 252.341820933644 95.951976839645 2.62987620729647 0.00879078257903463 FGFRL1 other 0.000414184778470601 1 8.23751126057854e-05 5.8711031775201 2.62987620729647 1.65067891221247e-24 121.738544432565 20.2585405425514 6.00924554149707 3.55029474189033e-09 -260.810951307145 45.4640314682629 -5.73664373537153 1.6571187222889e-08 TMEM175 other 2.11782104436859e-20 0.000224987008925164 3.865205885496e-05 6.00924554149707 -5.73664373537153 6.5653512984918e-16 58.8751371743096 8.24631866823428 7.13956609524479 3.0128235629136e-12 -11.5832192406641 14.5032844700412 -0.798661797235724 0.424835076828917 AUNIP other 6.98422071133558e-12 1 3.62442674618506e-08 7.13956609524479 -0.798661797235724 2.10772262581173e-14 138.313170919348 21.908075133359 6.31334200186038 5.73297447566996e-10 -274.153993017774 78.4113287954058 -3.49635693246709 0.000510765657123503 PIN1 other 2.12648135718146e-10 1 6.44329001320547e-06 6.31334200186038 -3.49635693246709 4.35683593091171e-47 73.7778394387955 5.34781505841168 13.7958846057604 2.81436907513347e-37 -97.9328914931647 20.0631283191093 -4.88123735917533 1.39220595480702e-06 FBXL12 other 6.53961073229847e-43 0.0175598937079809 4.22774522466549e-33 13.7958846057604 -4.88123735917533 1.94168185798879e-19 389.172707884676 57.1649336773295 6.80789223130009 2.61227084585672e-11 -224.723037659967 95.1698040719725 -2.36128507199636 0.018561346450382 EMC1 essential 2.27254444659008e-15 1 3.06132020425949e-07 6.80789223130009 -2.36128507199636 0.0502695119379959 -1.11722099846175 3.0596335789171 -0.36514862634537 0.715141606658195 -11.6620026041557 5.14980628208532 -2.26455170648349 0.0239307417092069 PLA2G5 other 1 1 1 -0.36514862634537 -2.26455170648349 2.27568238149816e-08 414.895108651518 150.4050399532 2.75851865589488 0.00600072001515454 -777.269958111641 246.509924892207 -3.15309802820931 0.00170408099608257 UBR4 other 0.0001724056972223 1 1 2.75851865589488 -3.15309802820931 3.99692735686445e-12 304.319660151076 165.621889419352 1.83743623030736 0.0666887549123097 -1415.88303565248 273.649166068536 -5.17408131000067 3.22230185114972e-07 HP1BP3 other 3.68796487217883e-08 0.00417481427834957 1 1.83743623030736 -5.17408131000067 4.47736993815773e-06 32.022427909195 6.62212948172088 4.8356692507428 1.72883348992035e-06 64.8304105420851 24.6120775957957 2.63408931203596 0.00867610001273991 ADGRE2 other 0.0280820642521253 1 0.0163962568184046 4.8356692507428 2.63408931203596 5.56634880005906e-34 351.913682829014 30.7370285982918 11.4491770635426 2.42236818378831e-27 -379.157596423221 110.934740915277 -3.41784361954559 0.000678441065300031 SIN3B other 7.88139326600363e-30 1 3.51655189240549e-23 11.4491770635426 -3.41784361954559 1.91466482065471e-25 619.455066450737 61.2872044059434 10.1074126721085 3.95983439802331e-22 -482.636119323361 227.469916119977 -2.12175802214126 0.034308631629885 SLC35E1 other 2.49021306574352e-21 1 5.54812397507046e-18 10.1074126721085 -2.12175802214126 1.37399042631835e-25 278.315344562799 28.9214638807381 9.62314168157162 2.37508664099543e-20 -340.873860921642 105.342272845355 -3.23586962493256 0.00128632940700045 EPS15L1 other 1.78934773219438e-21 1 3.27690703858139e-16 9.62314168157162 -3.23586962493256 0.00558141385240158 -23.7961158785536 46.1227272072824 -0.515930373579392 0.606111896390354 -521.301969724041 161.973946983928 -3.21843098492727 0.00136544586741347 KLF2 other 1 1 1 -0.515930373579392 -3.21843098492727 0.0619263641953288 9.2443668883726 5.18589354457211 1.7825986609479 0.0752092288433214 -19.000545698247 18.7175371118203 -1.01511996929596 0.310499906706507 F2RL3 other 1 1 1 1.7825986609479 -1.01511996929596 2.2479508659834e-11 309.487941236833 82.5763032918574 3.74790259310809 0.000198222327557086 -529.929133647032 147.847534170213 -3.58429470346756 0.000369687280929435 UQCR11 other 2.00269942650461e-07 1 1 3.74790259310809 -3.58429470346756 2.20673778170871e-23 155.206384911092 16.7035929012398 9.29179643138763 3.66753551333341e-19 -151.337024068606 76.3945644647427 -1.98099203953771 0.0480971714177192 GFER other 2.78115162628749e-19 1 4.99555012271144e-15 9.29179643138763 -1.98099203953771 0.00639641510648284 20.9660910840867 6.62817431320719 3.16317738390042 0.00164800925349753 19.1707547690718 30.3142259780694 0.632401262131542 0.527391392052833 SYNGR3 other 1 1 1 3.16317738390042 0.632401262131542 7.72901506966001e-08 288.216820987655 49.7315537191335 5.79545176922088 1.15701851352304e-08 351.306670096023 226.280573477389 1.55252686829135 0.121119901730249 PKMYT1 essential 0.000563445198578215 1 0.000123552052981029 5.79545176922088 1.55252686829135 0.0171043189169835 4.78414547085567 1.8554375046576 2.57844603164822 0.0101917369477418 -2.39403421100204 8.16563967769428 -0.293183915222431 0.769495689947083 WFIKKN1 other 1 1 1 2.57844603164822 -0.293183915222431 2.1611781283532e-22 119.256923839664 13.4518053574348 8.86549579560711 1.13849950154445e-17 -130.206831933304 58.8191881744915 -2.21367951470251 0.0272726543958818 WDR24 essential 2.68158982166065e-18 1 1.52308463316616e-13 8.86549579560711 -2.21367951470251 9.80627577344235e-15 255.487912690902 39.8728186314853 6.40757090819652 3.24538557942877e-10 -478.993925006276 174.409179101975 -2.74638025058426 0.00622862369061722 FBXL16 other 1.00180913301487e-10 1 3.68221447841989e-06 6.40757090819652 -2.74638025058426 4.27156118573113e-08 115.195507670225 19.7656790669989 5.82805717323201 9.67843581879024e-09 88.3357837500378 86.82937639866 1.01734905182851 0.309445539076499 CHTF18 other 0.000317248849264251 1 0.000103636690747606 5.82805717323201 1.01734905182851 0.000281116991362251 19.4939219601395 5.25251252005275 3.71135183128392 0.00022761762019725 -7.3500095046669 23.0821770701289 -0.318427914417946 0.750283940180335 GNG13 other 1 1 1 3.71135183128392 -0.318427914417946 1.0839157765049e-43 1435.62054002105 98.7491260572869 14.5380581817829 1.10893991454311e-40 -432.621065225822 330.089111873142 -1.31061901063881 0.190540569740849 SMARCA4 other 1.61145758492983e-39 1 1.67804787868664e-36 14.5380581817829 -1.31061901063881 3.14213948617102e-13 119.340630121013 164.51997083825 0.725386890800903 0.468526060698393 -3171.7451680638 448.589385815657 -7.07048643671474 4.75220024597843e-12 KDM4B other 3.03090774836056e-09 6.92870795863655e-08 1 0.725386890800903 -7.07048643671474 3.4463382574e-16 72.6213046551786 14.3628671752391 5.05618437942353 5.84786813908256e-07 -191.955226893514 38.8288357244519 -4.94362561514131 1.02188097025786e-06 TICAM1 other 3.69688704871298e-12 0.0129676695125723 0.00570634973011676 5.05618437942353 -4.94362561514131 8.47033382415812e-16 -0.740522561893475 4.24675413190036 -0.174373777923918 0.861637808650431 -89.8956924791613 10.7905712272879 -8.33094843503993 6.8005781055443e-16 METTL25 other 8.97855385360761e-12 1.02783937487197e-11 1 -0.174373777923918 -8.33094843503993 0.0351803291889214 -6.94307685283621 5.18090935052168 -1.34012706710205 0.180759413325682 19.9853560224106 12.3259781609017 1.62140121956444 0.105506808785995 IL17B other 1 1 1 -1.34012706710205 1.62140121956444 2.63876187228909e-21 105.161679657429 12.1795142142046 8.6343082168895 6.44876486383754e-17 -31.9762554311492 22.5070530173508 -1.42072155810441 0.15596645267063 EMC6 other 3.20609567483124e-17 1 8.53171591485706e-13 8.6343082168895 -1.42072155810441 1.25513605064737e-56 159.939052882951 21.6824761437054 7.37642010178723 6.1642080160862e-13 -482.198137010766 40.1514109958921 -12.0094941883886 1.29647403575352e-29 METTL16 other 1.92010713028035e-52 2.02807433412923e-25 7.52588156683964e-09 7.37642010178723 -12.0094941883886 0.0502655272547525 222.226510335373 94.8986583231017 2.34172446968383 0.0195574415691884 283.776318890611 213.602667445741 1.3285242281101 0.184566135965602 TUBA4A other 1 1 1 2.34172446968383 1.3285242281101 0.000805336934866372 91.711073327809 29.9351589892136 3.06365746581987 0.00229478311019454 -89.9387982150109 68.0484228958043 -1.32168820947879 0.186827534278744 VIL1 other 1 1 1 3.06365746581987 -1.32168820947879 8.05075754922881e-17 309.264094856631 65.5241737123359 4.7198473072604 3.00698780036688e-06 -890.691922049472 148.82965806135 -5.9846399813827 3.94139042337562e-09 AAMP essential 8.79545262253248e-13 5.44660742606278e-05 0.0280972940066281 4.7198473072604 -5.9846399813827 7.90816356072022e-06 151.059556389172 65.7336572626156 2.29805494901443 0.0219378476683285 -527.834972067908 149.367718726043 -3.53379549858436 0.000444558576332832 PNKD other 0.0485165834450185 1 1 2.29805494901443 -3.53379549858436 0.00203469114474846 -33.7681581281023 37.3462522917962 -0.904191346008768 0.366295658415321 -259.200007752216 75.5861824760055 -3.42919829076562 0.000651433224620566 TNFRSF19 other 1 1 1 -0.904191346008768 -3.42919829076562 3.70715456161447e-39 277.461574534482 25.7045319327268 10.7942667565644 1.01232963995563e-24 -194.508232487085 55.153325286902 -3.52668187231273 0.000456736292039273 RNF6 other 5.40762635902703e-35 1 1.44712522031658e-20 10.7942667565644 -3.52668187231273 3.39181626160339e-18 742.581253074048 108.427041562814 6.84867208743173 2.08716111185361e-11 -646.939453342045 215.27998096687 -3.00510735107136 0.0027814952646964 ECHS1 other 3.84598045903208e-14 1 2.45324917087274e-07 6.84867208743173 -3.00510735107136 0.0524885562849871 5.51668167146459 2.37687302426175 2.32098291122558 0.0206564930105901 -2.32131325315536 9.50541720695639 -0.244209507338252 0.807160640184411 ZNF835 other 1 1 1 2.32098291122558 -0.244209507338252 0.00227074474402423 -212.610649278593 151.247924523768 -1.40570953253102 0.160388699643821 -1742.20874332384 501.449657867174 -3.47434426565174 0.000553467719482813 AKAP9 other 1 1 1 -1.40570953253102 -3.47434426565174 0.904242991517692 15.1576399269089 38.7256744735189 0.391410611512367 0.695647862978339 -13.1270300505946 123.80042834691 -0.106033801545584 0.915594837884975 GNG11 other 1 1 1 0.391410611512367 -0.106033801545584 5.48259825420973e-14 390.365533062182 62.3798519109295 6.25787848325729 7.97409686679995e-10 -618.45772408331 198.492556027835 -3.11577288569241 0.00193250361741304 SEM1 other 5.44696136555737e-10 1 8.91105324864894e-06 6.25787848325729 -3.11577288569241 0.0220927310174492 8.34107012402163 3.44191540893066 2.42338033711672 0.0157038537904132 -7.04787533126265 11.0024893366355 -0.640570975860438 0.522072684398295 GNGT1 other 1 1 1 2.42338033711672 -0.640570975860438 0.000134417756425121 165.53273193258 68.8072210549179 2.4057465102458 0.0164822505169539 -705.126035085747 245.882709118736 -2.86773330915776 0.00429949229831148 HIP1 og 0.718866161361547 1 1 2.4057465102458 -2.86773330915776 7.61910094008582e-09 304.25577752409 65.400309639182 4.65220698805083 4.13039155418356e-06 -635.088560003936 218.255112673871 -2.90984505344863 0.00376433075381429 PTPN12 other 5.9390891827969e-05 1 0.0382143826593063 4.65220698805083 -2.90984505344863 0.517287687366495 -48.6805560596929 44.5429142600712 -1.0928911336035 0.274929816713995 12.4338495723481 149.653801218174 0.0830840878824139 0.93381552395259 FGL2 other 1 1 1 -1.0928911336035 0.0830840878824139 1.46606938252322e-15 152.321515426961 25.0104244403876 6.09032108951287 2.15624506936915e-09 -387.927519571089 87.5353558852674 -4.43166667511521 1.13526931466483e-05 STYXL1 other 1.54127874184667e-11 0.136595603940472 2.36626333912571e-05 6.09032108951287 -4.43166667511521 0.0810947982015825 175.588476035473 306.347255377246 0.573168105649413 0.566767286460225 -1909.99627293689 985.483037285675 -1.93813206384314 0.0531232022822567 STEAP4 other 1 1 1 0.573168105649413 -1.93813206384314 0.0164382293618467 85.7006799768845 29.8712778316991 2.86899946027551 0.00427798846852622 51.2117998593343 94.9756090423077 0.539210017979686 0.589962960660215 GNAI1 other 1 1 1 2.86899946027551 0.539210017979686 4.83339378493115e-11 8.21850683257498 1.75920346561068 4.67172046510383 3.80673468488204e-06 -25.7773687119632 6.3362398712301 -4.06824382217695 5.47075520168699e-05 PMS2P3 other 4.23453629497818e-07 0.629519801058122 0.0353188844063355 4.67172046510383 -4.06824382217695 6.9635626950238e-14 107.06234817601 21.381887837355 5.00715133249215 7.47125486736705e-07 -332.906575668112 70.8626587913531 -4.6979125726614 3.33159796310684e-06 PEX1 other 6.89531978061256e-10 0.0412918251547462 0.00724637009585931 5.00715133249215 -4.6979125726614 1.57773767407777e-15 34.5831515911896 5.95386815318772 5.80851821058108 1.07413934767599e-08 -87.9980295778966 19.6577688176999 -4.47650139718109 9.25131984753218e-06 MTERF1 other 1.65630901024684e-11 0.111940970155139 0.00011483623766004 5.80851821058108 -4.47650139718109 0.114757518504821 103.229526218454 51.7876557692747 1.99332301655754 0.0467306237104979 -8.23926490973516 165.46686356272 -0.0497940477768956 0.96030499037044 SGCE other 1 1 1 1.99332301655754 -0.0497940477768956 8.33321011875869e-15 26.6890088345958 6.81021503075619 3.91896712718516 0.000100248113033195 -133.206985595192 22.0853384468985 -6.03146679936431 3.00008438072459e-09 RBM48 essential 8.54237369273954e-11 4.15661690949393e-05 0.828550654219353 3.91896712718516 -6.03146679936431 0.05355595152444 315.197570552542 153.10499066533 2.0587021310202 0.0400036800815546 -332.244201392819 489.186124084461 -0.679177484877833 0.49731748965198 CASD1 other 1 1 1 2.0587021310202 -0.679177484877833 1.02621860289531e-18 54.5583989707125 6.95287452455519 7.84688387199147 2.2560239910527e-14 -137.383813791956 40.0418124532158 -3.43100887234994 0.000646764632130405 ZNF780B other 1.17850944356497e-14 1 2.84913269830045e-10 7.84688387199147 -3.43100887234994 9.87853542421488e-42 74.1426044098728 4.94740784900952 14.9861516722775 9.67523791938087e-43 60.445870882385 26.7876360241737 2.2564839550544 0.0244371752231375 LRFN1 other 1.45757790184291e-37 1 1.46928163043718e-38 14.9861516722775 2.2564839550544 0.0676844403825222 -84.5907200493795 174.923799521526 -0.48358611167127 0.628875662303756 -2222.71261552027 955.509368364556 -2.32620703586052 0.0203767321105423 ZFP36 other 1 1 1 -0.48358611167127 -2.32620703586052 0.000183116156327194 210.888172252767 71.1426274100588 2.96430115009992 0.00316942702945802 -311.123726114651 176.487384855536 -1.76286665683965 0.0784960071619088 SRD5A3 other 0.960993588405114 1 1 2.96430115009992 -1.76286665683965 0.00467503696778576 -22.4336776694858 11.6868857737209 -1.91955993271793 0.0554603790671387 -92.2780805903809 28.8608752677115 -3.19734172073493 0.00147140220745038 RASL11B other 1 1 1 -1.91955993271793 -3.19734172073493 7.45858058346719e-28 1349.50333890823 125.71002098248 10.7350498262689 1.76527314670752e-24 -298.234077209769 308.27873991072 -0.967416946417193 0.333772757412787 PAICS essential 9.99151454961264e-24 1 2.51992741692498e-20 10.7350498262689 -0.967416946417193 0.0298738585721883 -115.512179449123 46.1278795409777 -2.50417276056462 0.0125720136567015 -193.858401578236 114.434307865178 -1.69405840953424 0.0908394808230839 KDR og 1 1 1 -2.50417276056462 -1.69405840953424 5.52193990932441e-29 250.412324022116 21.88893985427 11.4401302981911 2.91334221855449e-27 11.1880826270949 53.6782568606547 0.208428575766505 0.834973671666885 PPAT essential 7.48719832305297e-25 1 4.22696822490072e-23 11.4401302981911 0.208428575766505 7.78117794374819e-15 99.4967065569877 27.3021520136091 3.64428073315951 0.000294442213860184 -306.190071255323 58.1982095357402 -5.26115964215855 2.07869390118894e-07 TUBGCP6 essential 7.98582292366877e-11 0.0027108247165405 1 3.64428073315951 -5.26115964215855 3.56443617601025e-16 143.105471849377 21.0487868923697 6.79875151860906 2.87768587847071e-11 -98.7973941053216 45.066130797904 -2.19227593663126 0.0287978404585709 ADM2 other 3.82107558068299e-12 1 3.36775578357427e-07 6.79875151860906 -2.19227593663126 1.56776144663807e-19 232.923451537728 37.5122701197053 6.20926035119834 1.0691839488803e-09 -247.735949276363 76.4129921576338 -3.24206580950664 0.00126058826515131 DGCR6L other 1.83882740076179e-15 1 1.18903946954979e-05 6.20926035119834 -3.24206580950664 1.23346844400463e-11 9.97454051541022 4.56794410140748 2.18359513469897 0.0294192854245197 -48.9984243590922 9.64788241175376 -5.07867138797201 5.23309445948275e-07 ASPHD2 other 1.11221849595898e-07 0.00672871285600293 1 2.18359513469897 -5.07867138797201 0.932337496178329 0.516828719310944 1.39411287697909 0.37072229074511 0.710987906244393 0.698477739512974 3.15089982669585 0.221675641223233 0.824649125259876 VPREB3 other 1 1 1 0.37072229074511 0.221675641223233 5.65332448760272e-09 128.724052138973 25.8917928860523 4.97161601382636 8.98018273894351e-07 -55.6440769626405 56.2889872308168 -0.988542869575326 0.323337926961635 SDF2L1 other 4.44351304725574e-05 1 0.00866587634308049 4.97161601382636 -0.988542869575326 3.21475178860205e-38 919.472892859218 95.263812762349 9.65185904487144 1.87027334571269e-20 -959.547260831463 197.979411229631 -4.84670226500728 1.63920815996059e-06 YWHAH other 4.6700699233022e-34 0.0206052597009682 2.58340857243294e-16 9.65185904487144 -4.84670226500728 2.04671638575681e-05 5.58127912023437 1.47548556621267 3.78267280144299 0.00017232550735377 -1.97364548397698 3.23024927304416 -0.610988600925227 0.541461859148958 POM121L9P other 0.120920004070512 1 1 3.78267280144299 -0.610988600925227 3.90467877092384e-08 50.2952853598017 13.2520559667274 3.79528168957939 0.000164013241944055 -67.432970668703 30.3095911226388 -2.22480634581494 0.0265028999387054 GNAZ other 0.000291249989523209 1 1 3.79528168957939 -2.22480634581494 0.0104061466083476 56.3091464601488 20.2477424310855 2.78100863105111 0.00560652213303995 9.23969764319549 41.8828317780142 0.220608236142374 0.82548010498681 MGAT3 other 1 1 1 2.78100863105111 0.220608236142374 0.000129981218864494 174.474468135277 57.718242681958 3.02286521605786 0.00262147951938589 -149.086043654997 127.9451815439 -1.16523374976684 0.244433193957293 ADORA2A other 0.69682931433255 1 1 3.02286521605786 -1.16523374976684 4.57817163887807e-24 1524.93850455054 178.612950840532 8.5376704061735 1.36873358858873e-16 -746.938177196073 369.464210584966 -2.02167938272955 0.043697653857393 ATF4 essential 5.83213285076678e-20 1 1.79933717555875e-12 8.5376704061735 -2.02167938272955 0.0235654953112222 41.6145882951826 26.2954512122 1.5825774564338 0.114095790916795 -63.9776715502821 52.0732416025515 -1.22860935062562 0.219746628452491 A4GALT other 1 1 1 1.5825774564338 -1.22860935062562 6.13238261163395e-12 556.014291917257 86.420858857132 6.43379734094567 2.7310531513407e-10 -28.6516000131775 177.761365453102 -0.161180130115149 0.872011369873125 CDC42EP1 other 5.61603599573437e-08 1 3.10466122244411e-06 6.43379734094567 -0.161180130115149 0.00414460053669176 16.7444075485228 40.7160332732538 0.41124849850052 0.681051695881472 -230.148539401708 83.9526889435172 -2.74140759870777 0.00631818234279436 APOL3 other 1 1 1 0.41124849850052 -2.74140759870777 0.0228396640824037 2.4757187343319 8.90482320780283 0.278019975979148 0.781103047548106 -37.9515476985214 16.7361711274592 -2.26763621198005 0.0237442289662224 MCHR1 other 1 1 1 0.278019975979148 -2.26763621198005 3.63458048580759e-10 72.0529925557521 29.2494550203201 2.46339607030954 0.0140718006048769 -269.940711666662 61.6405053332319 -4.37927480002554 1.4291301012114e-05 TPST2 other 3.04759573734967e-06 0.170895377502859 1 2.46339607030954 -4.37927480002554 0.0481959078067171 23.5762955626078 9.66587420709261 2.43912708333283 0.0150443575490896 15.6885416160934 19.8370147220763 0.790872106307098 0.429366475328353 BAIAP2L2 other 1 1 1 2.43912708333283 0.790872106307098 1.77507735925837e-11 248.519467688466 38.8519087132346 6.39658322896783 3.41811200180416e-10 3.25839589664673 79.3323789362098 0.0410727112982048 0.967252943825622 MPST other 1.58869423653625e-07 1 3.87545538764555e-06 6.39658322896783 0.0410727112982048 2.40900153914489e-08 131.537320429073 32.600383346564 4.03483968365474 6.24358304740762e-05 -138.860794574882 66.567282040234 -2.08602169592794 0.0374402333289433 TST other 0.000182168696390136 1 0.526021871744092 4.03483968365474 -2.08602169592794 0.0383146848496538 5.70143071003058 2.34523204860705 2.43107316967502 0.015374387249221 2.37342087555965 5.31927568574237 0.446192492320203 0.655634775708394 IGLL1 other 1 1 1 2.43107316967502 0.446192492320203 1.33656202878529e-10 138.07824548825 40.1827073466801 3.43626038676208 0.000634785891860883 -306.748152590356 82.9865107508998 -3.69636161123969 0.000240826529296848 APOL2 other 1.14583462727763e-06 1 1 3.43626038676208 -3.69636161123969 0.00285587847674858 -92.1535633039695 33.350453960243 -2.76318767396166 0.0059174428956501 -211.375355652512 68.1870739829487 -3.09993292431597 0.00203563236835754 RAC2 other 1 1 1 -2.76318767396166 -3.09993292431597 0.050698310817403 83.701343060608 34.56422628766 2.42161772591134 0.0157799872949193 58.7304913070992 71.797829585252 0.817998143486541 0.413719038815249 LIF other 1 1 1 2.42161772591134 0.817998143486541 1.42307712424113e-05 26.1834292391915 6.9222051996306 3.78252716931719 0.000172522313963278 -11.5977795149731 14.2454326689947 -0.814140207914899 0.415922174162504 C22orf23 other 0.0854130889969529 1 1 3.78252716931719 -0.814140207914899 7.39091598293158e-14 35.7066777727054 6.94135965194477 5.14404663684317 3.7592301595e-07 -43.4751539669429 14.4041786373977 -3.01823207427239 0.00266165887608097 APOBEC3F other 7.30739863232445e-10 1 0.0037171267817136 5.14404663684317 -3.01823207427239 1.20592522885351e-13 35.9402364623536 5.41202922676795 6.64080605562749 7.56101904508194e-11 -5.30470066985011 10.6423382757405 -0.498452551723741 0.618366201452387 RIBC2 other 1.18313324202818e-09 1 8.7390258123057e-07 6.64080605562749 -0.498452551723741 0.00220636685891466 771.735122814551 650.429369557676 1.18650103905881 0.235943356234329 6012.49831737181 1709.57019717075 3.51696486480766 0.000473044630689367 KRT17 other 1 1 1 1.18650103905881 3.51696486480766 9.10047775823844e-32 247.394482838287 36.7688259098898 6.72837591944281 4.38674356707088e-11 -407.84753888255 67.1745729936468 -6.07145711102805 2.39068419680905e-09 EMC4 other 1.26578545139338e-27 3.32042128094809e-05 5.10222144286014e-07 6.72837591944281 -6.07145711102805 0.00013982288593956 92.6121803669524 25.9398880651054 3.57026137254366 0.000388991276249605 -37.4577640925235 69.1665790000165 -0.541558721481867 0.588349682020272 SPECC1 other 0.745395804943796 1 1 3.57026137254366 -0.541558721481867 0.718268072673604 33.5199055320472 41.9112079918941 0.799783808152946 0.424185799685199 15.6001022321766 138.813241449544 0.112381946198173 0.910562101582987 CPA4 other 1 1 1 0.799783808152946 0.112381946198173 0.947350257560501 -2.80577186525081 19.2546511110304 -0.145719174503426 0.884197866565867 14.13076254823 60.1688942242542 0.234851624421807 0.814413587306479 DOCK4 other 1 1 1 -0.145719174503426 0.234851624421807 2.38799673208788e-16 66.8204331687494 18.356340716138 3.64018265960841 0.000298695707897835 -357.323532051417 56.7968946966393 -6.29125120237534 6.52128209587435e-10 POT1 other 2.57378287784431e-12 9.1760960371048e-06 1 3.64018265960841 -6.29125120237534 1.38712399610122e-18 339.512720986653 44.9085480573776 7.56009124483101 1.75807127456634e-13 -535.510278321612 164.81661014635 -3.24912809361934 0.00123016174100111 ATP6V1F essential 1.58728598873862e-14 1 2.17754708067787e-09 7.56009124483101 -3.24912809361934 8.60923368368723e-07 72.708395909465 25.1008290963795 2.8966531595545 0.00392429654570012 -261.563927491043 77.6350723606542 -3.36914643778454 0.000807748005461933 LSM8 other 0.00578712688217455 1 1 2.8966531595545 -3.36914643778454 0.191203729566509 -17.1988469913161 22.6826423860989 -0.758238246609946 0.448637327069029 -125.324413188059 69.2737485057052 -1.80911840186817 0.0709855162292232 CDHR3 other 1 1 1 -0.758238246609946 -1.80911840186817 1.05204839137649e-14 70.4563524273388 18.6202561979311 3.78385515636285 0.00017159478538215 -314.55134486932 54.0955841255362 -5.81473238442828 1.03724570582979e-08 PRKRIP1 essential 1.07298415436489e-10 0.000141729253244583 1 3.78385515636285 -5.81473238442828 0.293984186981769 8.61818372448585 7.72800248026847 1.11518904742723 0.265269164053906 -15.527909042576 22.5211201842413 -0.689482091278985 0.49081831478771 VGF other 1 1 1 1.11518904742723 -0.689482091278985 0.0398210807880634 385.367253051116 155.289651964082 2.48160291543605 0.0133790789745648 143.931487382877 511.211632712068 0.281549710868852 0.778395478372483 PODXL other 1 1 1 2.48160291543605 0.281549710868852 0.263841618849941 4.97386653401047 4.87607711099608 1.02005493776829 0.308160877264347 -13.1950200361533 14.9918463809819 -0.88014642765363 0.379172969361178 FOXP2 other 1 1 1 1.02005493776829 -0.88014642765363 0.110319987207283 -2.77540922832796 6.08870765867625 -0.455828951546569 0.648694217421707 -47.1151726532666 22.4536012101232 -2.09833479326358 0.0363344385403634 STRIP2 other 1 1 1 -0.455828951546569 -2.09833479326358 1.34548241517145e-17 73.2898116333928 18.9976388419957 3.85783792622588 0.000128154530242853 -370.3053882308 55.5075634938835 -6.67126000354176 6.27284626625188e-11 IFT22 other 1.50263476126348e-13 8.99588883043182e-07 1 3.85783792622588 -6.67126000354176 1.46132919648044e-11 147.299532895954 38.5949321051503 3.81655115999797 0.000150842753577709 -591.494180505706 129.22525101985 -4.57723375143492 5.84101550871186e-06 MKLN1 other 1.31358881471627e-07 0.0714998708421419 1 3.81655115999797 -4.57723375143492 0.000663956850187234 8.24026030934712 31.9560201906756 0.257862532949316 0.796611423678554 -345.699067288218 96.4474377064101 -3.58432609003611 0.000368616020028334 DNAJB9 other 1 1 1 0.257862532949316 -3.58432609003611 0.602400944794595 186.022450836779 192.970719247506 0.963993146536314 0.335483259480465 -0.655288416232354 704.874860265117 -0.000929652131423565 0.999258590267438 FLNC other 1 1 1 0.963993146536314 -0.000929652131423565 0.260886967964669 -5.80434486458746 3.62641566308992 -1.60057351496265 0.110051948065821 -10.6152968345424 13.0017132226299 -0.816453697507047 0.414598069327267 LRRC4 other 1 1 1 -1.60057351496265 -0.816453697507047 6.67433956873088e-21 1895.71220076569 189.847716820012 9.98543586680556 1.14026501412791e-21 1156.58073473785 689.113310851835 1.678360752179 0.0938520622930717 CALU other 8.05526042550129e-17 1 1.5912398272155e-17 9.98543586680556 1.678360752179 0.0139365531938388 7.01552843923843 2.64191035046929 2.65547558719858 0.00815313456052356 -4.2004804330935 9.6323896973203 -0.436078747339517 0.662953553765786 CCDC136 other 1 1 1 2.65547558719858 -0.436078747339517 5.42428991242629e-10 226.569291332432 34.3318529440278 6.59939012618439 9.76989322093071e-11 129.960064204203 126.601859627518 1.02652571286524 0.305097571340445 SMO og 4.50921220419998e-06 1 1.12578479584785e-06 6.59939012618439 1.02652571286524 3.83204236102276e-08 54.21106123136 9.43594491455485 5.74516508121408 1.5298401831392e-08 7.65673921675304 34.7537250190259 0.220314202651985 0.825709113877004 IRF5 other 0.000286023641826739 1 0.000162606713065866 5.74516508121408 0.220314202651985 0.00360411373538175 -68.5957442209638 23.3263519421128 -2.94069747344945 0.0034153718303899 -170.483812328113 69.3754278055669 -2.45740916806906 0.0143081633708394 LRRC17 other 1 1 1 -2.94069747344945 -2.45740916806906 2.94033946341786e-11 349.187516193505 62.4439798847587 5.5920125020528 3.55709286759861e-08 -594.919669628454 231.246909435627 -2.57265998097183 0.0103560388727839 KLHDC10 other 2.60631690037359e-07 1 0.000371787346521407 5.5920125020528 -2.57265998097183 1.3964440220171e-26 214.512488033619 35.0883210506874 6.11350106275367 1.86539695120953e-09 -793.540806765898 109.733910808759 -7.23150028024479 1.63652350583254e-12 NDUFA5 other 1.84330610906257e-22 2.39930711190109e-08 2.05305588450121e-05 6.11350106275367 -7.23150028024479 9.43832101487418e-09 5.13327126154841 0.839679033704754 6.11337315271511 1.86466219105843e-09 2.68753422476438 3.04788495042969 0.88177023361249 0.378291221643595 OPN1SW other 7.30997962602005e-05 1 2.05243367369802e-05 6.11337315271511 0.88177023361249 4.22654688441512e-38 266.786558102532 19.0006019179297 14.0409529790096 1.8990910420035e-38 88.5815712888423 101.149515423686 0.875748844844185 0.381552388078866 MRPS12 essential 6.13821404023608e-34 1 2.86136047298667e-34 14.0409529790096 0.875748844844185 0.000941686611062972 199.91936368535 107.664872197343 1.85686714343476 0.0638774259665039 -754.419266148896 275.748315951015 -2.73589800012746 0.00642687763577857 MYO1B other 1 1 1 1.85686714343476 -2.73589800012746 0.537550066523826 -0.112917272610801 4.45647934167738 -0.0253377753947581 0.979794973400252 -11.76676556639 10.9441529487437 -1.0751645761439 0.282784784928673 HOXD3 other 1 1 1 -0.0253377753947581 -1.0751645761439 2.34408745866409e-19 119.68375159684 17.5708985140344 6.81147589016263 2.58808456631478e-11 -198.968109428092 43.3017080358863 -4.59492519932925 5.3964317994825e-06 MTX2 other 2.73883178670313e-15 0.0662088217478508 3.03401153709081e-07 6.81147589016263 -4.59492519932925 0.000114084494091453 -9.09930849369131 6.44661864055828 -1.41148546254061 0.158681725888586 -67.1898110789695 15.6489867366919 -4.29355665063161 2.08738847494073e-05 PDE11A other 0.6153717611293 0.247105047663483 1 -1.41148546254061 -4.29355665063161 0.00152548922282013 59.9883091755906 18.3475396004907 3.26955605393468 0.00114553081031294 -23.5760663788092 44.7439592370381 -0.526910599348425 0.598471253457799 CHN1 other 1 1 1 3.26955605393468 -0.526910599348425 0.363442961937559 -19.5150452515778 24.8345170363978 -0.785803292368289 0.432326758666374 56.5073979718775 61.7365981225602 0.915298213544232 0.360442879475572 GAD1 other 1 1 1 -0.785803292368289 0.915298213544232 1.6736782167458e-09 13.7421986214414 5.99027954418423 2.29408302568839 0.0221694415561735 -79.6788893871416 15.1140189848882 -5.27185320243469 1.95753149916988e-07 OSGEPL1 other 1.35517725209908e-05 0.00255601102313684 1 2.29408302568839 -5.27185320243469 9.63567519397811e-16 123.436279880078 17.913292631148 6.89076444078433 1.55429085648374e-11 -144.562661966166 45.1968631700807 -3.1985109546687 0.00146254846472611 ORMDL1 other 1.01964714902676e-11 1 1.83421863973646e-07 6.89076444078433 -3.1985109546687 2.11331946811928e-08 104.837007581762 34.7859142324212 3.01377755609055 0.00270083742636138 -352.646667557192 85.5446308965796 -4.12237055512612 4.33772794430648e-05 HAT1 other 0.000160400947630253 0.502482405068462 1 3.01377755609055 -4.12237055512612 0.0420805266008657 -11.2307725996554 8.11350555663349 -1.38420717423103 0.166875391164489 -48.0185980192225 19.8468838478343 -2.41945276585383 0.0158781618189994 HOXD9 other 1 1 1 -1.38420717423103 -2.41945276585383 0.390906859892808 3.40268681543301 2.75845160876808 1.23354957709504 0.217914484776891 -1.5399262042036 6.71045939056791 -0.229481487715743 0.818582740899844 HOXD10 other 1 1 1 1.23354957709504 -0.229481487715743 2.14919651081548e-15 202.540344258174 59.0355634521133 3.43081919464467 0.000647897461416877 -607.868081645658 113.879724540798 -5.33780779762852 1.38833792903393e-07 HERC2 other 2.24655511275542e-11 0.00182677504702285 1 3.43081919464467 -5.33780779762852 6.02326564426103e-19 273.271279591967 82.8404326799364 3.29876692759178 0.00103582608151854 -1082.64404669755 165.153094288747 -6.55539668427102 1.31025210475223e-10 SNRPN other 6.95145088004165e-15 1.86907462742906e-06 1 3.29876692759178 -6.55539668427102 1.04856493422666e-32 215.959051330608 24.8255038340927 8.69908029959227 4.24029656205373e-17 -315.427409888409 59.6212191687147 -5.29052264087087 1.78902185861794e-07 PSMG2 essential 1.47092688973317e-28 0.00234036826036975 5.6268735378453e-13 8.69908029959227 -5.29052264087087 3.82970230203495e-06 9.0237331388118 50.042928032042 0.180319847252623 0.856969124387724 -481.010616038307 108.624461790982 -4.42819792252579 1.15059877186939e-05 TWSG1 other 0.024211377953465 0.138382514292732 1 0.180319847252623 -4.42819792252579 0.00524001686024939 20.1893360736729 6.25130628086706 3.22961876551546 0.00131409770294683 9.92924756432069 16.4500297045051 0.60360058569386 0.54635989616358 ARHGAP22 other 1 1 1 3.22961876551546 0.60360058569386 5.66173144058827e-18 254.561862686676 57.1050258132027 4.45778386510808 1.00690720308482e-05 -502.555468487922 100.829608436103 -4.98420529726048 8.38422431742937e-07 EIF2AK4 other 6.38643306498357e-14 0.0106856938925637 0.0907122699259112 4.45778386510808 -4.98420529726048 8.78834737857209e-33 156.165433806549 64.3059898491589 2.42847414638765 0.0154898129604229 -1552.95449945098 141.18633401523 -10.9993258928549 1.61457524913403e-25 MYO5C other 1.23388397195152e-28 2.51566969567572e-21 1 2.42847414638765 -10.9993258928549 7.00094349746775e-05 -68.8270399612408 89.3847318842028 -0.770008909915462 0.441630078885024 -715.163150426901 166.129158714542 -4.30486228883972 1.98325225259231e-05 CGNL1 other 0.388412345239511 0.235114554544819 1 -0.770008909915462 -4.30486228883972 0.000161206491346552 75.7098594042067 21.3826278255722 3.54071819524739 0.000433575700299365 160.662368527319 47.0244008534922 3.4165744934821 0.000681993614766597 TMOD2 other 0.853104752205951 1 1 3.54071819524739 3.4165744934821 2.86507579783013e-14 3.92828098227518 17.2096490876308 0.228260376622006 0.819532534077887 -204.404083937987 29.665623290359 -6.8902676319097 1.59722170242911e-11 TTBK2 other 2.87624959344166e-10 2.31229785860662e-07 1 0.228260376622006 -6.8902676319097 5.46237474960363e-13 101.055042789067 21.9880330668429 4.59591098857561 5.43554252164357e-06 -124.825663173725 38.5341038837952 -3.23935554723561 0.00127595265991108 ELL3 other 5.20837432374706e-09 1 0.0499308936038178 4.59591098857561 -3.23935554723561 5.10543680238735e-27 95.3365727856629 24.7588371900505 3.85060784776979 0.000131866200257327 -343.28905612812 43.512547384724 -7.88942676908498 1.68180010152186e-14 INO80 essential 6.7759357241285e-23 2.51462751179548e-10 1 3.85060784776979 -7.88942676908498 3.20673306743098e-38 623.301214356644 48.7622943808422 12.7824423003674 6.90335212751001e-33 -190.377006355128 100.078497641298 -1.90227682111575 0.0576647590457 ICE2 other 4.65874180036373e-34 1 1.02494069037141e-28 12.7824423003674 -1.90227682111575 0.00532405506313317 12.7580603641467 15.6008990885093 0.817777250642144 0.413842420475253 -65.6063035288142 27.4088258643603 -2.39361962652045 0.0170208516771708 DLL4 other 1 1 1 0.817777250642144 -2.39361962652045 0.862401804009836 -4.91645726401776 9.05582797888741 -0.542905328533172 0.587418167845708 -2.73888886633831 16.8293402186055 -0.162744874769978 0.870779970925256 ALDH1A2 other 1 1 1 -0.542905328533172 -0.162744874769978 6.84916315710561e-13 12.9067971297724 36.456995750955 0.354027995557869 0.723455583549353 -468.11977235115 66.43585789367 -7.04619142723153 5.61000688585427e-12 MINDY2 other 6.50944466451317e-09 8.17321903200109e-08 1 0.354027995557869 -7.04619142723153 6.95558617502776e-43 413.175427842242 94.4687995683111 4.37367077522216 1.46456589659264e-05 -1795.31322194688 167.064229079445 -10.7462455119171 1.47350784569959e-24 IVD other 1.03116565044787e-38 2.29292555869314e-20 0.130170616889154 4.37367077522216 -10.7462455119171 2.61990648731753e-05 99.5220720219182 21.8301090406002 4.55893609311912 6.35798845492365e-06 113.438801109974 38.6184754902268 2.93742307716632 0.00345000883438769 KNSTRN other 0.152897742599851 1 0.0581183724664571 4.55893609311912 2.93742307716632 8.6444237083314e-14 224.712438342462 42.208828911184 5.32382546825222 1.49680049355087e-07 -214.039265968542 73.943337044265 -2.89463898336656 0.00395061355441815 DUT essential 8.52513066115643e-10 1 0.00151191817853573 5.32382546825222 -2.89463898336656 0.000637280745097273 11.29147082339 7.1006511994562 1.59020215276237 0.112370185572008 48.0809064919019 12.4749548821069 3.85419482044503 0.000129972481736118 CHAC1 other 1 1 1 1.59020215276237 3.85419482044503 2.13348825359243e-13 282.633122624084 37.0639470310822 7.62555381344206 1.1022909830717e-13 36.3665093034368 80.573156544885 0.451347705152621 0.651920170470004 CLN6 other 2.07225714071433e-09 1 1.37124998294119e-09 7.62555381344206 0.451347705152621 1.81334508782425e-32 1094.07545446907 130.468238970484 8.38576088021374 4.39335581543265e-16 -1563.99547017624 266.99882689349 -5.85768667365771 8.1553036233555e-09 ARPP19 other 2.53832045393639e-28 0.000111825523283451 5.72542129867183e-12 8.38576088021374 -5.85768667365771 9.61103510722068e-26 1038.00512830276 101.51356244295 10.2252852064581 1.56853281859042e-22 -285.713693503563 208.412164947116 -1.37090698892774 0.170980923701601 VPS13C other 1.25452841254552e-21 1 2.2047297298107e-18 10.2252852064581 -1.37090698892774 9.72502468515412e-14 79.0688833332681 10.2864500900309 7.68670266624809 7.17570831457285e-14 6.05424501157255 22.3616700266745 0.270742078044736 0.786692863694061 CALML4 other 9.56942429019165e-10 1 8.96676510989024e-10 7.68670266624809 0.270742078044736 0.421464650664985 -126.746869340149 205.561806146489 -0.616587642014715 0.537766117264699 -521.584492251193 404.617067598597 -1.28908178625978 0.19792055765007 ISLR other 1 1 1 -0.616587642014715 -1.28908178625978 1.43196271146225e-20 26.2126732460654 3.18303805604488 8.23511148296988 1.37332671889609e-15 -20.9893427759336 6.8678841466512 -3.05615853845875 0.00235340829262727 THAP10 other 1.71391616934916e-16 1 1.77323945943863e-11 8.23511148296988 -3.05615853845875 0.00197779576325787 -189.010684108464 71.8054480349431 -2.63226105095096 0.0087236681606832 -428.898056166553 141.977537284789 -3.02088671467965 0.00263926357721366 LOXL1 other 1 1 1 -2.63226105095096 -3.02088671467965 0.681954253992458 3.03377622864058 3.83346324606428 0.791393065201626 0.429058304518294 6.62186788982631 13.1689947800942 0.502837764036151 0.615281101475824 ACKR4 other 1 1 1 0.791393065201626 0.502837764036151 1.439745593832e-13 107.700850807511 27.4909985850229 3.91767692520951 0.000100792939521222 -590.977468125387 97.0650428700375 -6.08846862527697 2.15497000445397e-09 ANAPC13 essential 1.40778324164893e-09 2.99648579119325e-05 0.832650473384818 3.91767692520951 -6.08846862527697 1.05512078718582e-20 192.85588356568 20.8532177231932 9.24825540718276 5.27181600455183e-19 -136.3476432787 67.1178306401153 -2.03146677981584 0.0426968284954885 MBD4 other 1.26698904125273e-16 1 7.17125131099186e-15 9.24825540718276 -2.03146677981584 2.64670727604088e-18 645.799923687854 133.669627763771 4.83131384811777 1.77397924721301e-06 -1633.46470609646 304.710931111243 -5.36070268348895 1.23474007636822e-07 COPB1 essential 3.0103648557689e-14 0.00162751089466095 0.0168137753050849 4.83131384811777 -5.36070268348895 2.14537956053778e-19 430.587709435933 61.07787657125 7.04981465643512 5.54283711773761e-12 -435.836091471917 137.81372776977 -3.1625012872449 0.00165276615981056 PSMA1 essential 2.50923593400499e-15 1 6.62202750456112e-08 7.04981465643512 -3.1625012872449 3.49109414621671e-09 346.048074045535 83.0259144380888 4.16795257706651 3.59439296944464e-05 -1417.72374177577 359.551799450763 -3.94303058402553 9.13688986056301e-05 SUMF2 other 2.77716539331539e-05 1 0.309405346809794 4.16795257706651 -3.94303058402553 0.216510821595177 -174.152735884403 246.344949998399 -0.706946644879606 0.479904579675992 -944.410115942583 539.64476511822 -1.75005888500687 0.0806761077244842 PALLD other 1 1 1 -0.706946644879606 -1.75005888500687 8.00280035085698e-13 268.366887922468 83.3610919741401 3.21933028427362 0.00136225915191766 -854.880283832893 175.111083178884 -4.88193133360722 1.38613043661864e-06 SPCS3 essential 7.58425389250716e-09 0.0174874215883807 1 3.21933028427362 -4.88193133360722 0.456853034272911 -26.9586982771104 25.2191756273104 -1.06897619000346 0.285562468381468 -62.8338682584375 64.4420004332112 -0.97504527848355 0.32997845713849 BBOX1 other 1 1 1 -1.06897619000346 -0.97504527848355 2.34418638291521e-09 23.0640531220064 16.6135857646148 1.38826460757981 0.165625754547265 -221.536085057257 41.685669964602 -5.31444223507449 1.56440986803754e-07 SERGEF other 1.88378817731066e-05 0.00205281862883885 1 1.38826460757981 -5.31444223507449 0.288415187403493 20.1553091925088 16.188594049226 1.24503147902906 0.213657215177839 -17.9813933287157 40.619309900231 -0.4426809163642 0.658172834020611 KCNC1 other 1 1 1 1.24503147902906 -0.4426809163642 0.355426944521221 -99.6437902572154 74.135629728743 -1.34407424097974 0.179482586036621 -181.159244377792 187.086895806774 -0.968316052263199 0.333315273632208 TPH1 other 1 1 1 -1.34407424097974 -0.968316052263199 0.0739264244478038 41.9108320752926 112.308714459379 0.373175245367548 0.709163385660808 642.638078755659 286.084114437094 2.24632563055845 0.0250835439788307 CSRP3 other 1 1 1 0.373175245367548 2.24632563055845 5.44462947270694e-09 66.5787822840593 10.9348328294896 6.08868771221691 2.15221168995419e-09 98.9300240047873 27.854311943653 3.55169512730792 0.000415967022348711 E2F8 other 4.2805676914422e-05 1 2.36205232972473e-05 6.08868771221691 3.55169512730792 1.46073548581146e-27 143.397206351816 36.9607549899114 3.87971529236773 0.000117442662591068 -655.956783027969 77.8031319400457 -8.43098171849229 3.11252780560112e-16 DCTD other 1.95066616775262e-23 4.71205584489954e-12 0.963617046559716 3.87971529236773 -8.43098171849229 0.781656160781014 9.51887933904118 13.6913360691768 0.695248388539011 0.487195971929884 5.29800811694674 24.4822753250207 0.216401786460273 0.828755548357257 SOX15 other 1 1 1 0.695248388539011 0.216401786460273 4.56974681875266e-14 107.418841309885 14.4513430352351 7.43313898562773 4.14259312147485e-13 153.500989036954 26.372308611487 5.82053665829215 1.00295041721827e-08 PIMREG other 4.55101085679577e-10 0.00013711335153791 5.07881916692817e-09 7.43313898562773 5.82053665829215 3.11124879288935e-52 130.060505488939 16.939248372202 7.67805646573864 7.50539098384834e-14 -334.44599911584 30.7431562839342 -10.8787138193294 4.40604472518605e-25 RPAIN essential 4.72412016712319e-48 6.86065224158719e-21 9.37423333882658e-10 7.67805646573864 -10.8787138193294 0.0423697416798691 2.88623738175358 5.77300715179401 0.499953889864255 0.617312344289044 -22.1409021985333 10.848981042826 -2.0408278078036 0.0417564070884487 USP6 other 1 1 1 0.499953889864255 -2.0408278078036 2.83090784408854e-28 74.1774035000564 25.415270571642 2.91861553434818 0.00366137619365577 -441.720104199266 47.557183398385 -9.28818892613953 3.7365019525131e-19 PLD2 other 3.80926959500554e-24 5.73478319671711e-15 1 2.91861553434818 -9.28818892613953 0.192707751454607 -76.4817370879774 177.064999896059 -0.43194158717349 0.665954701568776 443.551455470081 316.73867744553 1.40037035908366 0.161971483729378 CD68 other 1 1 1 -0.43194158717349 1.40037035908366 3.80268381905509e-25 278.848995182992 33.7340481756839 8.26609939402386 1.05719830820538e-15 -207.143419728213 60.7494447724021 -3.4097993900072 0.000698152949152706 TXNDC17 other 4.92029259347538e-21 1 1.36780317115612e-11 8.26609939402386 -3.4097993900072 0.948005796370437 -2.3798691468253 7.65886914326119 -0.310733752243212 0.756121839216917 -0.615546574515838 13.6952699207902 -0.0449459249854875 0.964166874067291 ATP1B2 other 1 1 1 -0.310733752243212 -0.0449459249854875 5.48181914571211e-60 299.786380687271 24.9828343542125 11.9996945277237 1.33380664272208e-29 -347.894342179564 44.673260956335 -7.78752960343787 3.46634666888809e-14 FXR2 other 8.42336329930123e-56 5.16624307531081e-10 1.9570944868661e-25 11.9996945277237 -7.78752960343787 6.20584435373806e-17 614.155927153243 109.873742737527 5.5896514658682 3.60902431637994e-08 -817.754166424505 204.473731510179 -3.9993116004918 7.23438881690403e-05 KIF1C other 6.80160541169691e-13 0.824069230133538 0.000377179131304867 5.5896514658682 -3.9993116004918 6.68966165049457e-50 210.148527346973 44.4603870863409 4.72664637262086 2.9093976500859e-06 -986.650805264259 79.5319470968887 -12.405716712333 2.65462700324014e-31 MPDU1 other 1.01154373817128e-45 4.15608403627277e-27 0.0272086868236033 4.72664637262086 -12.405716712333 9.783545642673e-56 330.230796493151 18.5945921464264 17.7595073821835 6.18723924421788e-56 -203.107437554178 172.902317374222 -1.17469470993024 0.24063366050137 PHF20L1 other 1.49355607781046e-51 1 9.53206077964207e-52 17.7595073821835 -1.17469470993024 0.00224194799664604 15.7218062752785 7.08434692918701 2.21923155831144 0.0268865412719974 -165.034583388447 65.6770648874851 -2.51281910467797 0.0122678187315911 LRRC6 other 1 1 1 2.21923155831144 -2.51281910467797 1.66818196974883e-07 104.628951431214 27.9903338996418 3.73803870315933 0.000205091799762752 -259.125760904688 82.7679041676016 -3.13075175106486 0.00183723248367553 CCNT1 other 0.00118807919885512 1 1 3.73803870315933 -3.13075175106486 4.01763343717729e-09 96.8291673620249 19.4860730957102 4.96914729234704 9.11544529951071e-07 -162.435921864598 60.1028782869886 -2.70263132971725 0.00710205825607876 PUS7L other 3.18477802565044e-05 1 0.00879275853590803 4.96914729234704 -2.70263132971725 2.56705702270929e-35 244.05445120414 20.9193575564582 11.6664410245618 3.33300879201389e-28 -258.844124909881 68.7176031613313 -3.76678046092763 0.000183541462605885 KRI1 essential 3.67140495387882e-31 1 4.86052672139386e-24 11.6664410245618 -3.76678046092763 9.90890232993548e-19 956.761344766931 116.795076557281 8.19179517638053 1.89239975699805e-15 -931.948750258589 383.993861334692 -2.42698866856701 0.0155526718475751 ILF3 essential 1.13833469966299e-14 1 2.44006024667329e-11 8.19179517638053 -2.42698866856701 1.57183181315946e-20 1786.01834780547 182.247241916352 9.79997463349935 5.62467625265432e-21 498.684576214826 602.510614835297 0.827677660668513 0.408219371503948 SLC44A2 other 1.88053958126397e-16 1 7.80648817105893e-17 9.79997463349935 0.827677660668513 4.08937950686586e-18 555.637578774389 69.933653004936 7.94521028002314 1.13875622345288e-14 -588.966831329463 226.585647991422 -2.5993121654014 0.00959700750338915 AP1M2 other 4.62835972587079e-14 1 1.44804241374268e-10 7.94521028002314 -2.5993121654014 3.40622327614165e-14 78.357936196226 9.72608547412576 8.05647209297935 5.06119122104133e-15 38.4861561476285 31.9490347693699 1.20461091940486 0.228881225600884 CDKN2D other 3.41201385571109e-10 1 6.47376969083396e-11 8.05647209297935 1.20461091940486 8.50584561558457e-14 866.874672072022 214.112000977801 4.04869726177515 5.9040807065566e-05 -1217.23390618772 437.754471089817 -2.78063157906153 0.00561469571042739 MTUS1 other 8.39101669977418e-10 1 0.498186330019246 4.04869726177515 -2.78063157906153 0.927579206576971 5.5628166915052 14.6717395582207 0.379151815599691 0.70472280364462 -0.149628330486 53.4164701099887 -0.00280116470028633 0.997766021856687 KLK14 other 1 1 1 0.379151815599691 -0.00280116470028633 0.679170318471523 -0.482898658718309 2.44036666686916 -0.197879550345538 0.843213087894996 -7.81621033404813 8.88482054912088 -0.87972630294953 0.379395326725883 SIGLEC9 other 1 1 1 -0.197879550345538 -0.87972630294953 0.827751486478296 -16.0744832734573 59.4512611733661 -0.270380862511602 0.786969619516522 104.818549012066 216.477869059204 0.484199837459592 0.628438565740522 KLK10 other 1 1 1 -0.270380862511602 0.484199837459592 0.0823185284779687 1.93886063546859 23.2356793641667 0.0834432514359205 0.933529737826105 186.722074234739 84.6072943722706 2.20692643134486 0.0277352908041146 KLK8 other 1 1 1 0.0834432514359205 2.20692643134486 4.31297645919775e-101 321.313594958119 12.4575480740338 25.7926835239639 3.74090646127811e-96 -21.2870070708649 41.2181909474585 -0.516446903213192 0.605754127502746 NGDN other 6.73686922926688e-97 1 5.84366998316254e-92 25.7926835239639 -0.516446903213192 1.20199978210792e-11 0.0963977948961602 11.4506969028771 0.00841850899677023 0.993286242780443 -212.24979771476 30.8275702742759 -6.88506411067602 1.63632775654224e-11 RIPK3 other 1.08468460337419e-07 2.36825716204358e-07 1 0.00841850899677023 -6.88506411067602 1.27612529967175e-08 -28.7480901267949 12.2215712873569 -2.35224174133277 0.0190240916638473 -204.323602634644 33.4010849254551 -6.11727442658392 1.84602473962109e-09 ADCY4 other 9.79936617617934e-05 2.57114325734426e-05 1 -2.35224174133277 -6.11727442658392 1.94278639398548e-25 67.835180534197 11.8152313620869 5.74133323803279 1.55726360809727e-08 -235.140083605173 32.9094990680608 -7.14505204466572 2.88150453887148e-12 RAB2B other 2.52601086945992e-21 4.21420038809955e-08 0.000165412540452092 5.74133323803279 -7.14505204466572 1.33975737494268e-20 187.027087496391 26.4063229285937 7.08266304256514 4.41968571091196e-12 -412.529891558605 87.7100706281252 -4.70333553039374 3.25322460079878e-06 BCL2L2 other 1.60489535944384e-16 0.040336731825304 5.29434151310143e-08 7.08266304256514 -4.70333553039374 4.95364870949674e-09 63.7826523546016 17.8290906028236 3.57744843949026 0.000378097057298426 -239.205833843419 60.0811718222406 -3.98137763609449 7.78753899128741e-05 AJUBA other 3.90446591282533e-05 0.884664429410249 1 3.57744843949026 -3.98137763609449 3.42692970690547e-51 128.222534583937 7.76254373036879 16.5181078571322 1.02519664800264e-49 -37.6694873634167 32.5094343536712 -1.15872478596856 0.247092178619987 DTD2 other 5.194882742698e-47 1 1.57060126474004e-45 16.5181078571322 -1.15872478596856 2.62419129898891e-30 141.847705546744 12.8650763647016 11.0257958464931 1.14142307011815e-25 -62.0416318884544 35.9356754844432 -1.72646349489973 0.0848276494787252 PARP2 other 3.59907836656328e-26 1 1.64090980560186e-21 11.0257958464931 -1.72646349489973 6.54844562370292e-58 331.461207758778 18.3740517726983 18.0396361052651 5.48340108322153e-57 -35.007720656339 77.3857532861127 -0.452379400209591 0.651182191751145 HEATR5A other 1.00368026074495e-53 1 8.45650115054424e-53 18.0396361052651 -0.452379400209591 5.08307958505913e-32 51.436540668819 255.998709400241 0.200924999931936 0.840833867679033 -7976.42510139719 653.704352976073 -12.2018846365081 2.26234029125239e-30 FOXA1 other 7.08581294157243e-28 3.54033632178087e-26 1 0.200924999931936 -12.2018846365081 2.38556691605213e-28 373.865599243729 33.0174774875933 11.3232635468356 9.47003809295233e-27 -72.791743615465 86.3724710698762 -0.842765556129288 0.399742620873011 SNX6 other 3.21216585246419e-24 1 1.37003041090741e-22 11.3232635468356 -0.842765556129288 8.82480506979685e-48 251.144496538088 21.0617257083397 11.9242126697455 3.46369196430002e-29 -423.805534316536 55.0912523462646 -7.69279180028065 7.12604375395291e-14 EAPP other 1.32725068249745e-43 1.05978522708788e-09 5.07223051252095e-25 11.9242126697455 -7.69279180028065 0.0107305055595171 139.026892545647 72.5237435312451 1.91698450433341 0.0557802996484507 -331.643646082551 189.994907502671 -1.74553965915054 0.0814737593131696 EGLN3 other 1 1 1 1.91698450433341 -1.74553965915054 0.190084892082494 42.9294027073956 23.6401018716433 1.8159567560447 0.0699450983306592 21.1740697680611 54.6684015563707 0.38731825268803 0.698676982785044 MIS18BP1 essential 1 1 1 1.8159567560447 0.38731825268803 9.40632399370219e-33 8.55985238596519 1.14588644349974 7.47007038482965 3.25225061653695e-13 -29.9978796518079 3.59123323845771 -8.35308587884724 5.65687260148094e-16 NRL other 1.3201775725161e-28 8.55375706069933e-12 4.00221960871038e-09 7.47007038482965 -8.35308587884724 0.0437165161208804 373.661064425773 156.694469820898 2.38464742790774 0.0174352364741303 666.752642390293 439.450316514426 1.5172423760637 0.129783196548318 RNASE1 other 1 1 1 2.38464742790774 1.5172423760637 2.5209825320641e-42 501.39247406075 40.356298299424 12.4241443142447 2.53321386195542e-31 -568.776829989942 115.477776099246 -4.9254224423331 1.12304462927253e-06 NEDD8 other 3.72878526317601e-38 0.0142300984975123 3.74206351688054e-27 12.4241443142447 -4.9254224423331 2.99095622136105e-55 839.528787293256 53.6265040824956 15.6551093840049 6.68198312873039e-46 -605.975979801296 170.894193906617 -3.54591321067598 0.000424861494895147 DAD1 essential 4.56270371568628e-51 1 1.01920288662525e-41 15.6551093840049 -3.54591321067598 3.42916556507386e-19 98.4393877596068 24.0492040420754 4.09324930618834 4.8942201209266e-05 -457.53309343777 67.286728201106 -6.79975242770459 2.74743202671936e-11 TEP1 other 3.98503330317233e-15 3.9639949281507e-07 0.415812941473924 4.09324930618834 -6.79975242770459 4.95745639702026e-17 49.1757010639515 34.0014012170031 1.44628454427814 0.148672247640167 -580.266590052006 76.005454623586 -7.63453876995741 1.02168298516286e-13 EPB41L4A other 5.45121905416348e-13 1.51740356956389e-09 1 1.44628454427814 -7.63453876995741 0.0141537993684471 53.1379525306976 19.8677566143701 2.67458241824161 0.00770859638382452 -3.96976281561132 44.5345822068997 -0.0891388808177992 0.929004526293084 CDO1 other 1 1 1 2.67458241824161 -0.0891388808177992 7.86385205618801e-34 1014.49182480136 213.154725125846 4.75941513472154 2.49179524309318e-06 -4625.151759302 476.684748064949 -9.70274752460052 1.23074818596292e-20 REEP5 other 1.11249915038892e-29 1.89965982503376e-16 0.0234153998993466 4.75941513472154 -9.70274752460052 2.00512146491403e-36 189.359134837702 34.1360578252183 5.5471881318941 4.77071686661966e-08 -695.332920096959 91.5135186807025 -7.59814429738001 1.55220849499076e-13 ITFG1 other 2.88476825157181e-32 2.29990732702782e-09 0.000496106846959778 5.5471881318941 -7.59814429738001 0.000424238550897518 29.8124501411809 8.67880637894867 3.43508644385638 0.000637653165445075 75.8492260791476 28.2362960378881 2.68623143691975 0.00744755618333203 QRICH2 other 1 1 1 3.43508644385638 2.68623143691975 0.00481961299571682 26.0655398859818 15.7504293044234 1.65490980481792 0.0985227651078643 -134.706049800893 55.1704394164126 -2.44163452794287 0.0149402562841829 FOXJ1 other 1 1 1 1.65490980481792 -2.44163452794287 1.10181906287535e-13 282.530778058892 35.5718183899157 7.94254527451951 1.16800605178446e-14 154.023715210869 103.814789346369 1.48363943307714 0.13849127457905 SEC14L1 other 1.0818761378373e-09 1 1.4847692930284e-10 7.94254527451951 1.48363943307714 1.09990529793182e-25 196.99261967467 18.6001782309474 10.5908995725056 5.97084109198473e-24 369.270199711056 59.3509885463668 6.22180369283269 9.8385230264993e-10 RHBDF2 other 1.43438649903288e-21 1.37847546124282e-05 8.49949229444026e-20 10.5908995725056 6.22180369283269 2.24025645283688e-160 646.605954472945 15.6056125285058 41.4341925568015 1.09475520482626e-155 -104.75184422437 99.0229483730228 -1.05785422415182 0.290689433709205 ASH2L other 3.50958575901425e-156 1 1.71504350388082e-151 41.4341925568015 -1.05785422415182 3.23347096242301e-77 118.403744212382 8.85864124266094 13.365903525044 3.42879528603204e-35 -161.210180473331 20.4274395136323 -7.89184471043211 1.80198603660846e-14 TTI2 essential 5.02255044593167e-73 2.69360872752233e-10 5.1267347116751e-31 13.365903525044 -7.89184471043211 0.541895201051515 3.18477135666133 2.99351276989703 1.06389102083934 0.287850948031946 0.882115550799447 6.53498894689215 0.134983480150943 0.892674955828444 CHRNA10 other 1 1 1 1.06389102083934 0.134983480150943 0.040330736046854 41.0552562071883 27.0338882338085 1.51865894584282 0.129429295713132 -59.6839448688452 54.209143812411 -1.10099405139804 0.271386162372188 CDKN1C other 1 1 1 1.51865894584282 -1.10099405139804 3.68537414429638e-15 63.0665870735267 9.18903574424719 6.86324319861413 1.8595338239568e-11 141.148395436779 20.8510709095249 6.7693595235102 3.39238705179649e-11 SGO1 other 3.82468128695079e-11 4.88673354811285e-07 2.18811345064997e-07 6.86324319861413 6.7693595235102 7.66081025515272e-08 65.9908300184986 25.2044791013649 2.61821836321644 0.00909622497776333 -152.165568038261 45.5866322280637 -3.33794273893709 0.000904341088189707 KLF16 other 0.000558626283805737 1 1 2.61821836321644 -3.33794273893709 3.13641292703709e-13 318.213611167827 44.4464906802303 7.15947662678727 2.73503662959369e-12 -80.482763018923 195.489943333706 -0.41169771521974 0.680728387052115 TMEM8A other 3.02601119200538e-09 1 3.29325760569377e-08 7.15947662678727 -0.41169771521974 8.01020637497521e-08 44.0866382043372 12.1755439695219 3.62091733352495 0.000321110790983907 -74.8900829211932 27.7024626337144 -2.70337276188763 0.00707942844191574 DOHH essential 0.000583062922034446 1 1 3.62091733352495 -2.70337276188763 8.07486217854769e-16 167.170410170633 32.6510910178823 5.11990273400289 4.28716378378418e-07 -531.507252367047 105.396919058371 -5.04291071423719 6.30977359398572e-07 MAU2 essential 8.56339134034983e-12 0.00808281997389571 0.00422457119254093 5.11990273400289 -5.04291071423719 4.3179895530738e-07 51.2305013767405 41.7915198956204 1.22585877481114 0.220806696963015 -306.317569268692 75.0459365834541 -4.08173424457238 5.17335105678072e-05 SHC2 other 0.00297639019893377 0.596280442804545 1 1.22585877481114 -4.08173424457238 0.00143945004052909 -28.534517561205 32.6832713342312 -0.87306185691758 0.383028503015911 -205.363629178544 58.4486369672379 -3.51357430787745 0.000480283445936387 PLPPR3 other 1 1 1 -0.87306185691758 -3.51357430787745 0.211985308408962 60.3646619370918 121.965659264409 0.494931625025922 0.620847486769263 418.428477900493 242.678136976421 1.7242116785376 0.0852356406574984 INS-IGF2 other 1 1 1 0.494931625025922 1.7242116785376 7.94757034590457e-11 61.4265157481384 27.7901936473828 2.2103665964891 0.0275135370037722 -240.474303166383 50.263341378926 -4.78428804311858 2.23755161371843e-06 ABHD17A other 6.89451727507221e-07 0.0279649200682529 1 2.2103665964891 -4.78428804311858 0.00253255439623372 -56.7728115869889 82.2884355356396 -0.689924546717142 0.490541917719713 1930.63035256058 587.473864553968 3.28632551854265 0.00108185037094557 LBP other 1 1 1 -0.689924546717142 3.28632551854265 0.0515930172706084 9.04045944934431 6.70546289577319 1.34822302201433 0.178149812579643 56.4541813915989 25.6202353786793 2.20349971642255 0.0279793719367502 SYT5 other 1 1 1 1.34822302201433 2.20349971642255 0.576734760393109 7.12478615494019 9.38117286796907 0.759477120314769 0.447897992722284 -21.9185460020809 35.800149890187 -0.612247324922203 0.540631368642036 TNNI3 other 1 1 1 0.759477120314769 -0.612247324922203 2.79157553190539e-07 90.9999533444604 28.4993700762755 3.19305139379954 0.00149089479812368 -94.9999638863192 61.2329355379436 -1.55145205846699 0.121386930845861 CBFA2T3 other 0.00195242792701463 1 1 3.19305139379954 -1.55145205846699 2.0380871526159e-10 4.43615134226736 69.8733197407445 0.0634884868606086 0.949401554455551 -743.621847187938 125.123824408774 -5.94308758305337 5.0842302737412e-09 GAMT other 1.73583882788297e-06 7.0075945862975e-05 1 0.0634884868606086 -5.94308758305337 1.01484856236611e-42 47.4159055058161 11.2012379310779 4.23309510944861 2.70883375471211e-05 -241.602684237375 22.6597313764828 -10.6622042522587 3.22773321680401e-24 ERMARD other 1.50319369057668e-38 5.01944792545192e-20 0.235641448322406 4.23309510944861 -10.6622042522587 4.9603771004162e-20 213.529938357405 46.3723564371713 4.60468164145835 5.15660059359908e-06 -495.247512470432 93.7727112995338 -5.28136070299264 1.86210704169195e-07 PHF10 other 5.87903893941328e-16 0.00243377390349137 0.047435568860518 4.60468164145835 -5.28136070299264 4.15915114438166e-05 -8.15792841216577 12.112291094571 -0.67352479794862 0.500900051515998 -201.975338986165 44.7767378270075 -4.51072027101406 7.92311555079889e-06 CRACR2A other 0.237820262435744 0.0962579308266557 1 -0.67352479794862 -4.51072027101406 2.0746787776127e-08 -21.03399883303 9.4287049474991 -2.23084707286435 0.0260996496693343 -127.643733663108 21.1282832823624 -6.04136795958541 2.84178630166142e-09 NXNL2 other 0.000157592599947461 3.94013670725355e-05 1 -2.23084707286435 -6.04136795958541 2.08155042388261e-12 -68.3900423653996 155.874840444821 -0.438749718493598 0.661016138268765 -2187.19063557147 302.310387539237 -7.23491724308546 1.58249782154031e-12 SH3BP4 other 1.94146208035531e-08 2.32041655572455e-08 1 -0.438749718493598 -7.23491724308546 7.08763169743121e-15 161.61169717889 21.4407379928028 7.53759955618785 2.02421908022881e-13 -103.5787807796 72.5786523214195 -1.42712460849913 0.154119812971909 DOCK6 other 7.28395909545006e-11 1 2.50355415842699e-09 7.53759955618785 -1.42712460849913 4.98210283374026e-33 223.032879933676 19.478664030539 11.4501117522229 2.51052315129894e-27 -213.745906459213 68.0148410551723 -3.14263627089604 0.00176622748246908 ECSIT other 7.00782584593905e-29 1 3.64427540642554e-23 11.4501117522229 -3.14263627089604 1.72912473041201e-26 186.112206222094 22.3775300763573 8.31692352047057 7.38903184258436e-16 -432.333246965984 78.136988705414 -5.53301648974384 4.91380853849314e-08 ELOF1 other 2.28002386952127e-22 0.000657025339681917 9.59244113804301e-12 8.31692352047057 -5.53301648974384 0.247542419507094 4.09179947444323 2.655065750756 1.54112924445586 0.123868941812751 -2.022609363481 8.98761479569006 -0.225044064466461 0.822029815721114 ANGPTL8 other 1 1 1 1.54112924445586 -0.225044064466461 2.03191574083656e-26 1543.67485042072 149.399164083322 10.3325534643539 5.86282144682947e-23 -1037.99574476851 500.12114586092 -2.07548861582663 0.0384140425934445 PRKCSH other 2.67603303068175e-22 1 8.2753724721998e-19 10.3325534643539 -2.07548861582663 0.0717915512145059 -142.898703246324 81.0534084622306 -1.76301905074 0.0784628444748716 -533.737019201277 283.019137498108 -1.88586900490022 0.0598490620572248 CNN1 other 1 1 1 -1.76301905074 -1.88586900490022 1.8899036885455e-50 287.841625367247 22.3946210861088 12.8531589911915 3.8520479631932e-33 -480.132429351284 64.5685946234894 -7.43600557130009 4.15017061289134e-13 CDC16 essential 2.86131418445789e-46 6.12233168813731e-09 5.72337286371245e-29 12.8531589911915 -7.43600557130009 8.37687919943471e-34 354.127941114583 26.9387931778298 13.1456497986712 2.4389667304983e-34 -71.843952962908 194.46539211544 -0.369443386205497 0.711945662506619 THEM6 other 1.18474202517605e-29 1 3.63845056855736e-30 13.1456497986712 -0.369443386205497 0.0602391272232122 -4.54636460460879 2.31182223834525 -1.9665718796195 0.0497386604250038 -13.1460706538452 6.84668908117718 -1.92006245617115 0.0553706746123077 EXOC3L2 other 1 1 1 -1.9665718796195 -1.92006245617115 6.02844656731078e-11 409.297552589688 164.8544618266 2.4827811637892 0.0133354143670874 -3036.03152823978 545.037409370482 -5.57031769937846 3.99612817204562e-08 NECTIN2 other 5.25801109600846e-07 0.000535960710434758 1 2.4827811637892 -5.57031769937846 0.797899897323011 190.507327562311 349.62464521856 0.544891014313992 0.586050963735386 616.216247478783 1155.91964433716 0.533096094090639 0.594183975034921 APOE other 1 1 1 0.544891014313992 0.533096094090639 1.32666109210934e-14 271.175543368297 32.9963695986209 8.21834482602084 1.50782174814832e-15 203.964494455075 109.091714020939 1.86966073716585 0.0620659228745395 TOMM40 essential 1.34894899845678e-10 1 1.94614553033504e-11 8.21834482602084 1.86966073716585 0.45253268220003 -10.8058580604719 74.935845996824 -0.144201455481398 0.885394599870067 286.926131392031 247.750888380894 1.15812352184549 0.247319955776926 APOC1 other 1 1 1 -0.144201455481398 1.15812352184549 0.000602554411879866 4.63695873961044 33.9340223677963 0.136646304094234 0.891361115125788 -271.43682124835 74.8592363335599 -3.62596300126379 0.000315051046685598 GADD45G other 1 1 1 0.136646304094234 -3.62596300126379 0.00469877156616952 3.28931003781984 2.75085256907937 1.19574203095904 0.232317239838011 27.8887819372908 8.47819870167126 3.28947019510091 0.00106858643742868 DPP6 other 1 1 1 1.19574203095904 3.28947019510091 2.37121695666345e-43 451.601345214117 58.7645676735356 7.68492585060732 7.2078859347783e-14 -655.148566688879 118.873013458529 -5.51133135795738 5.50993518949932e-08 XPO7 other 3.52102005894956e-39 0.000735576347798159 9.00481189831853e-10 7.68492585060732 -5.51133135795738 8.06161445008192e-29 102.127574120562 9.12247311876506 11.1951630649899 2.52807762739711e-26 -130.492501493822 54.9645260663508 -2.37412219903973 0.0179368205499324 FAM98C other 1.09105889967409e-24 1 3.64902724738498e-22 11.1951630649899 -2.37412219903973 4.44736898780758e-14 35.2612445330729 26.4508354217267 1.33308623228245 0.183062530984959 -433.659350350159 62.3738298655473 -6.95258494283505 1.0333064459493e-11 SAFB2 other 4.43180319635025e-10 1.49994763694001e-07 1 1.33308623228245 -6.95258494283505 7.71911780085376e-10 2149.40537295791 456.889872874565 4.70442769815564 3.23375487869104e-06 -2881.93906022228 1082.41560111808 -2.66250694949831 0.00798607993439064 RPL36 essential 6.3551496854429e-06 1 0.0301353617145218 4.70442769815564 -2.66250694949831 2.04721028709549e-05 18.6561693046716 10.4714279402708 1.78162609828255 0.0753926204773601 -56.546258190342 18.9393771042047 -2.98564508638398 0.00296284108048601 ATP8B3 other 0.120920004070512 1 1 1.78162609828255 -2.98564508638398 0.00197668539731001 9.96240787579342 3.45509687134641 2.88339466207533 0.00409186202296339 32.5536542775807 11.5839842797096 2.81022949371585 0.00513124064458131 GDF1 other 1 1 1 2.88339466207533 2.81022949371585 0.94285421581729 -41.3101730346913 121.945181098854 -0.338760192591812 0.734924812118396 -60.851819741008 397.917797630069 -0.152925604492765 0.878515256392555 NCAN other 1 1 1 -0.338760192591812 -0.152925604492765 0.0128141838056919 319.146809447504 119.11466886045 2.67932415462115 0.00759963448957109 495.169523873584 231.445420984396 2.13946563197277 0.0328407145411655 KIF1A other 1 1 1 2.67932415462115 2.13946563197277 3.5985630880839e-26 139.461712113112 13.713103580034 10.1699597978802 2.34481584688714e-22 -110.667141923603 47.7488289683232 -2.31769331970465 0.0208368060438903 GTPBP3 other 4.72599290358059e-22 1 3.29141800427548e-18 10.1699597978802 -2.31769331970465 0.00393467322083674 -134.429652072318 77.2727764132692 -1.73967674402383 0.0824824122715334 -865.958613041843 269.062693454513 -3.21842690981698 0.00136589471417836 PLVAP other 1 1 1 -1.73967674402383 -3.21842690981698 0.0133140485335509 634.440196835583 335.934153620235 1.88858498011727 0.0594801865489293 -1964.19305332779 1169.71787985221 -1.67920238474594 0.0936878772720044 BST2 other 1 1 1 1.88858498011727 -1.67920238474594 1.30378600567586e-07 52.8904337232386 28.6443872305177 1.84645017181199 0.0653738783156976 -469.593369916173 100.269967745081 -4.68329032587339 3.57603361368912e-06 SLC27A1 other 0.000935622596492781 0.0442283837341071 1 1.84645017181199 -4.68329032587339 1.63741110665822e-13 141.32843588265 21.7817927033689 6.48837484624445 2.01820497140017e-10 -256.146570810535 83.3694442200553 -3.07242747276126 0.00223408317676706 NSUN5 other 1.59811324009842e-09 1 2.30216641087618e-06 6.48837484624445 -3.07242747276126 0.00828491441131358 -4.53396792126675 3.26943183226035 -1.38677548696042 0.166078218520305 -35.2861393811968 11.5695846267208 -3.04990546503293 0.00240062546821347 USHBP1 other 1 1 1 -1.38677548696042 -3.04990546503293 1.03845331613498e-17 735.495644222507 80.5581407113799 9.12999775972497 1.36392256892184e-18 470.301041158725 278.242374951052 1.6902567096096 0.091555968817201 COLGALT1 other 1.16296386873957e-13 1 1.84634198154949e-14 9.12999775972497 1.6902567096096 1.03539532524763e-22 198.100031276064 21.1175230842617 9.38083649704647 1.76804366667561e-19 -152.394519407707 71.6874068589384 -2.1258199464179 0.0339688775362557 DDA1 other 1.29206982637652e-18 1 2.41850693164557e-15 9.38083649704647 -2.1258199464179 1.67196124360142e-19 165.956449007819 19.6048155105488 8.46508598453901 2.38642294676934e-16 -160.408950243792 69.3758376921806 -2.31217316546899 0.0211406215356905 MRPL34 essential 1.95987296974958e-15 1 3.12502084879445e-12 8.46508598453901 -2.31217316546899 4.45026039589758e-08 174.258499528186 40.2446149346112 4.32998302533937 1.77727182920649e-05 -375.562026359711 141.083175900363 -2.66199016263246 0.00799904637855758 PGLS other 0.000330031310959765 1 0.156790920772596 4.32998302533937 -2.66199016263246 1.00635303451833e-05 174.736324560959 42.2334087466859 4.13739571932305 4.08367141765459e-05 -20.347566586994 77.2365589848097 -0.26344475795453 0.792309993663066 LSM7 essential 0.061206391559405 1 0.349725620207939 4.13739571932305 -0.26344475795453 1.07448265296846e-12 203.231523779124 52.558077716417 3.86679902708168 0.000123608605736064 -426.768047669625 111.126703693165 -3.84037349697679 0.000137306290293571 TULP4 other 1.01409672787163e-08 1 1 3.86679902708168 -3.84037349697679 8.9330533313654e-21 197.391560925961 52.1285134538389 3.78663322330794 0.00016977011452807 -691.534991343462 110.565716619545 -6.25451552693338 8.0951149247569e-10 SNX9 other 1.07500363789651e-16 1.13631128198813e-05 1 3.78663322330794 -6.25451552693338 7.95927572003266e-79 88.4213469819008 4.14697959194565 21.321866920598 3.94787272899595e-73 16.1799252896449 13.8921235510979 1.16468337112984 0.244676132003921 RTN4IP1 other 1.23750818895068e-74 1 6.1365733699513e-69 21.321866920598 1.16468337112984 1.28975183087921e-100 263.396624831398 10.429384741817 25.2552409707641 1.17307265075383e-92 28.6728890071095 35.0072459365617 0.81905583372851 0.413126906702408 QRSL1 essential 2.01433440946715e-96 1 1.83093179329658e-88 25.2552409707641 0.81905583372851 4.65285132070812e-103 148.498934007286 5.75433301612016 25.8064546475293 2.19545993460078e-95 20.7228568141903 19.3149793667599 1.07289044532211 0.283814118377592 C6orf203 other 7.27008018860644e-99 1 3.4288693258595e-91 25.8064546475293 1.07289044532211 9.64323663856692e-23 36.7667569999909 17.2052412642781 2.13695096948897 0.0330465333990689 -290.47608171708 36.317164400251 -7.99831392439528 7.61026952191509e-15 RSPH3 other 1.20415095905785e-18 1.14154042828726e-10 1 2.13695096948897 -7.99831392439528 3.35490025917995e-34 280.511260509619 42.1593787254865 6.65359094440455 6.98839997602246e-11 -856.589919725115 100.596509641534 -8.51510577034421 1.6319251088773e-16 MLLT1 other 4.7595969976986e-30 2.47530400514509e-12 8.08418109226278e-07 6.65359094440455 -8.51510577034421 8.63519316236881e-11 961.054985119943 175.074713353339 5.48939916400333 6.21319387733957e-08 -366.269784940378 359.879862694343 -1.01775570935866 0.309249829371726 AFDN other 7.46857856613279e-07 1 0.000642319983039364 5.48939916400333 -1.01775570935866 4.71672414545524e-42 3337.31824483378 227.457375747301 14.6722797353533 2.56417851527883e-41 -590.689820217794 1234.98962879267 -0.478295369002617 0.632631793494876 ACTN4 other 6.96943159732466e-38 1 3.88498686849895e-37 14.6722797353533 -0.478295369002617 0.531356025147665 -0.233026523851756 2.71850870208262 -0.0857185131220058 0.931721723313511 5.58492771406928 5.67072195011517 0.984870667826669 0.325125423425131 STK33 other 1 1 1 -0.0857185131220058 0.984870667826669 1.18806422765978e-18 235.136053393125 61.0616902726018 3.85079502947578 0.000131635146791134 -782.820963579008 117.78710444113 -6.646066793927 7.28163808370023e-11 NDUFA10 other 1.36199683058917e-14 1.04294902272838e-06 1 3.85079502947578 -6.646066793927 0.784486157600158 1.90154392091513 5.2274330909871 0.363762460048257 0.716177770862082 11.3853662404199 16.887215103955 0.674200344481515 0.500472454011043 EPO other 1 1 1 0.363762460048257 0.674200344481515 5.30952503032257e-05 406.738157933295 115.667219013495 3.51645143198125 0.000474078617749304 -609.35310185747 366.742314271561 -1.66152930312335 0.0971865106686634 ARPC1B other 0.298873163956857 1 1 3.51645143198125 -1.66152930312335 2.04937913452244e-12 107.30119540767 14.2777973474304 7.5152485216483 2.44838148809674e-13 100.83394972773 57.742127196443 1.74628048226705 0.0813437731208271 CACNG6 other 1.91201401196118e-08 1 3.0220372707578e-09 7.5152485216483 1.74628048226705 2.67560887968256e-05 30.0938649992004 24.5469788477686 1.22597021759099 0.220742277478303 -198.164225120034 55.7701220525976 -3.55323276741519 0.000413723591736256 ZSWIM6 other 0.15601475377429 1 1 1.22597021759099 -3.55323276741519 0.00105735271865286 29.2621396566733 7.85534225955347 3.72512599576236 0.000215798339125824 29.1873772318918 26.7635581281681 1.09056415787902 0.27595199221476 FCHO1 other 1 1 1 3.72512599576236 1.09056415787902 0.512807536524404 -18.0152741435558 20.868036689101 -0.86329511548946 0.388359201232121 33.3401606693632 67.3279645588038 0.495190384676551 0.62066754398207 UNC13A other 1 1 1 -0.86329511548946 0.495190384676551 1.23727279795059e-11 133.85178092094 23.9511060855837 5.5885427772167 3.63685166347029e-08 -224.902084437641 78.3059236046963 -2.87209541864279 0.00423782353268925 MAP1S other 1.11552515463225e-07 1 0.000380014630316011 5.5885427772167 -2.87209541864279 0.0926103872001535 97.9505551529166 50.6136083277713 1.93526125461345 0.0534959573191531 -14.1358646076932 108.43751488661 -0.130359540445709 0.896332003599538 KLHDC7B other 1 1 1 1.93526125461345 -0.130359540445709 1.54227711281762e-12 222.118061372513 35.2540916379631 6.30049027084637 6.28516291350859e-10 -93.1214636706492 75.4801458650178 -1.23372129986579 0.217858800184851 SCO2 other 1.44696438724549e-08 1 7.05069575637394e-06 6.30049027084637 -1.23372129986579 2.33798425605134e-09 1421.67864038947 221.530437401075 6.41753186184326 3.00824274185571e-10 1107.99233066745 684.38635090657 1.61895737575677 0.106033882027705 PXDN other 1.87927174501407e-05 1 3.41616045765134e-06 6.41753186184326 1.61895737575677 1.8287224568723e-08 94.5432941039378 21.9426496471596 4.30865440702035 1.95066709953013e-05 -241.407212770915 81.4204093187759 -2.96494717713542 0.00316061236354834 SSBP4 other 0.000139275502315394 1 0.171658704758651 4.30865440702035 -2.96494717713542 0.0813511643230623 80.2607654807352 71.1808799498419 1.12756073733974 0.260003465451448 -414.611649416277 264.143227330919 -1.56964709489542 0.117079745783452 GDF15 other 1 1 1 1.12756073733974 -1.56964709489542 1.55427705476792e-12 66.7139347017306 22.9002979272226 2.91323435676463 0.00372406846821905 -505.524944243639 84.9863226947776 -5.94830942455525 4.85178202607145e-09 PGPEP1 other 1.45791187737231e-08 6.69157777035774e-05 1 2.91323435676463 -5.94830942455525 2.77481766847696e-10 56.6686519518597 9.79598208737911 5.78488725748795 1.22420703586966e-08 -67.2090658375632 36.3569573298263 -1.8485888471868 0.0650586548589822 KIAA1683 other 2.34139114866086e-06 1 0.000130622890727292 5.78488725748795 -1.8485888471868 1.31738950052819e-12 458.714601128869 63.9310040582556 7.17515089722159 2.37675859455585e-12 -109.22135232554 237.25721640666 -0.460349969453971 0.645448992166779 LSM4 essential 1.23940004209692e-08 1 2.8661331891749e-08 7.17515089722159 -0.460349969453971 4.61581170198866e-07 402.679529676291 138.71502276439 2.90292660197482 0.0038468964331158 -1904.13526704824 514.791542220677 -3.69884722432364 0.000238579828853295 JUND other 0.00317060105809601 1 1 2.90292660197482 -3.69884722432364 0.642099483302316 10.603633632899 16.6601760100558 0.63646588286335 0.524740023962905 -27.8934125285963 55.4452641807067 -0.503080162765324 0.615111158793666 HRC other 1 1 1 0.63646588286335 -0.503080162765324 1.82724183344997e-09 171.231950822667 53.748849354208 3.18577891210728 0.00152626371226662 -843.308723242453 182.539723301301 -4.61986414787364 4.79696636433856e-06 TRPM4 other 1.47787319489434e-05 0.0589787014495426 1 3.18577891210728 -4.61986414787364 0.030082851850906 9.67727488842201 3.85053706222026 2.51322730622984 0.0122495309214737 3.53126526151119 7.65741838077463 0.461156108483911 0.644869917760285 SULT4A1 other 1 1 1 2.51322730622984 0.461156108483911 8.94431300605822e-84 130.720148484658 5.78616287212062 22.5918542864572 2.75177825767922e-80 -16.4744743797367 21.7505585497566 -0.757427646837188 0.449120445678014 ZNF557 other 1.39262953504327e-79 1 4.28616981416116e-76 22.5918542864572 -0.757427646837188 9.15400311064074e-20 64.7080754706924 12.6366467585267 5.12066822054908 4.22967253009686e-07 -179.703310512089 30.1055670811434 -5.96910564839173 4.30112873595958e-09 CRB3 other 1.07962312686897e-15 5.9381383328658e-05 0.00417045711467551 5.12066822054908 -5.96910564839173 0.00066320903310496 20.5295680158131 49.9858066100261 0.410707947077427 0.681448717822874 -406.910021396597 118.816160552098 -3.42470266254883 0.000661985413602911 OLFM1 other 1 1 1 0.410707947077427 -3.42470266254883 5.47250003304582e-19 269.307642677723 30.1136565382865 8.94304025601558 6.07846327392163e-18 -5.30243313727078 71.1878812973753 -0.074485053363518 0.940652120024241 CAMSAP1 other 6.32621003820097e-15 1 8.1676311011685e-14 8.94304025601558 -0.074485053363518 2.55996075038784e-19 203.287230778417 23.4606759752544 8.6650201806989 5.37133083142684e-17 -59.0837744583834 55.7912750548636 -1.0590145932367 0.290071026241888 UBAC1 other 2.98747419570261e-15 1 7.11701335164056e-13 8.6650201806989 -1.0590145932367 2.03004270565952e-39 93.3221553089141 6.39433185538047 14.5945123618176 1.49083562739954e-40 113.815449429532 49.7256741259425 2.28886689683214 0.0224958445369534 ZBTB46 other 2.96487737161573e-35 1 2.25533613713002e-36 14.5945123618176 2.28886689683214 1.8823877620211e-15 338.788599235689 39.8249735265683 8.50693846688118 1.98670828884801e-16 193.410219171439 283.985060548656 0.681057724648517 0.496143466908905 HELZ2 other 1.97123646438849e-11 1 2.60477323750863e-12 8.50693846688118 0.681057724648517 6.12464322016764e-29 69.627919124276 5.72992973375003 12.1516183198824 5.52340217626103e-30 90.8809667946008 43.351643373531 2.09636728212453 0.0365466058471645 SAMD10 other 8.30256634925926e-25 1 8.11829651866846e-26 12.1516183198824 2.09636728212453 0.210647865952529 212.248903684953 318.763628932903 0.665850443463326 0.505788416589649 1116.87117326604 635.828485822841 1.75656045328116 0.0795543331736855 TNNT3 other 1 1 1 0.665850443463326 1.75656045328116 0.192131932951183 137.396301435867 211.293120052951 0.650263962221933 0.515795742003857 760.010182963636 421.460205600591 1.80327863191877 0.0718966384266221 TNNI2 other 1 1 1 0.650263962221933 1.80327863191877 0.14335708446797 -13.3281017651242 9.20444253788708 -1.44800749314947 0.148189971962042 -55.0823379221439 31.9515491844466 -1.72393324668454 0.0852869803770942 CYP2G1P other 1 1 1 -1.44800749314947 -1.72393324668454 0.00872258951725537 -1068.19666823933 628.217628534437 -1.70036086177861 0.0896346218211586 -4511.66444510194 1491.16570109702 -3.02559564090214 0.0025987516139127 COL5A1 other 1 1 1 -1.70036086177861 -3.02559564090214 9.92606998800201e-53 533.624555531887 64.1956839265237 8.31246779990157 7.47821061357627e-16 -1151.94767487949 126.211274533971 -9.12713764386737 1.35440620765019e-18 ATXN10 other 1.50876263817631e-48 2.07616927570698e-14 9.706717376422e-12 8.31246779990157 -9.12713764386737 2.79715338695182e-22 227.662406285109 40.1524896919392 5.66994495314727 2.3561247508411e-08 -457.826368951684 80.026250524219 -5.7209523869062 1.77783677455615e-08 TUBGCP2 essential 3.46343532372374e-18 0.000241074666629814 0.000248382671233669 5.66994495314727 -5.7209523869062 0.223091237423897 13.6511347802606 19.0766620996477 0.715593467502507 0.474561754917269 -43.7541713828115 37.7773599191372 -1.15821146518623 0.247306361628192 CYP2E1 other 1 1 1 0.715593467502507 -1.15821146518623 4.8400467608332e-05 16.3406149188793 23.8334948657495 0.685615559569567 0.493273321738871 -221.500774888047 55.4412637145458 -3.9952331539285 7.43522684589851e-05 PNPLA7 other 0.274237049468809 0.846277519600168 1 0.685615559569567 -3.9952331539285 5.97363367652078e-22 383.067538726832 40.6678274900968 9.41942469929365 1.28260869746918e-19 -448.233528266824 217.600544187386 -2.05989157766458 0.0398840524929306 PAK4 other 7.35414041916474e-18 1 1.75627608944455e-15 9.41942469929365 -2.05989157766458 5.56415379974819e-05 22.1405978116386 4.96163941880067 4.46235527066786 9.87811185596268e-06 19.1259769755236 14.5243502051812 1.31682152422219 0.188459089124979 MNX1 other 0.312594160469853 1 0.0890768550999027 4.46235527066786 1.31682152422219 4.51274609665246e-18 99.8217879301937 14.0770876985101 7.09108233663688 4.24001561817986e-12 -245.264820021844 61.7241074729153 -3.97356608403721 8.05314203861351e-05 ZNF337 other 5.1016594622656e-14 0.914031621382634 5.08165871838857e-08 7.09108233663688 -3.97356608403721 1.36436979930571e-12 189.107594363378 29.0682399676779 6.50564308584401 1.75383952997043e-10 -0.672140566726988 48.1354882832119 -0.0139635140454451 0.988864199770089 CEP85 essential 1.28278048530723e-08 1 2.00569088647418e-06 6.50564308584401 -0.0139635140454451 5.91839316744414e-06 13.4766350960218 3.20889154135086 4.19977893374001 3.14940871248687e-05 75.2068778854269 23.7773217558917 3.16296674022135 0.00165402354574228 GATA5 other 0.036658527279149 1 0.272707300414238 4.19977893374001 3.16296674022135 0.0362649280884559 10.4361534188805 4.46966425927942 2.33488530983375 0.0199327081708679 -26.7515152962489 33.1230217599072 -0.807641147301044 0.419670060491507 RBBP8NL other 1 1 1 2.33488530983375 -0.807641147301044 6.83683380192023e-76 404.615503851946 18.253704301673 22.1662133430561 3.53179693665661e-77 417.704966615795 134.684579340917 3.10135702735864 0.00203069663020348 OSBPL2 other 1.06100823772e-71 1 5.49547603343768e-73 22.1662133430561 3.10135702735864 9.4154403029171e-46 691.029158285015 43.3654085737586 15.9350316533896 7.91456966099455e-47 935.031323781016 318.036537838792 2.94001227071265 0.00342830008706008 ADRM1 essential 1.40911479573457e-41 1 1.20847564153726e-42 15.9350316533896 2.94001227071265 3.08457233597153e-07 844.874369377004 177.868035499793 4.75000675080817 2.60920241690707e-06 1712.20095586423 395.399731215869 4.33030379307326 1.77477172928484e-05 ASS1 other 0.00214994691817216 0.21103810632926 0.0244847554802559 4.75000675080817 4.33030379307326 5.59084710238291e-24 138.551269637095 13.4707346748572 10.285353618886 8.76930703062748e-23 5.71187090177609 29.9453741351128 0.190743013461922 0.848798493779876 EXOSC2 essential 7.10932117539011e-20 1 1.23612151903725e-18 10.285353618886 0.190743013461922 1.4684590249099e-20 84.1750215294654 17.163817890348 4.90421315742348 1.24118254521068e-06 -257.21258393427 40.0346773423085 -6.42474477151458 2.89040910070638e-10 POMT1 other 1.75730491510967e-16 4.09686585934122e-06 0.0118843228703922 4.90421315742348 -6.42474477151458 2.41378929842454e-23 85.750976618531 16.2183618277693 5.28727731747277 1.80335157959528e-07 -260.426082722826 37.8328283321188 -6.88360067708005 1.61916492784905e-11 UCK1 other 3.04040900029555e-19 2.3437412330615e-07 0.00181435202423082 5.28727731747277 -6.88360067708005 0.0388115171113426 23.7194375246171 16.1383682386769 1.46975438742137 0.142208501467445 -54.3683584578476 37.0105676271466 -1.46899553137276 0.142414153341166 FIBCD1 other 1 1 1 1.46975438742137 -1.46899553137276 1.3211787900164e-25 1185.12770649969 185.020342272662 6.4053913853061 3.25710683059663e-10 -2795.05863420123 431.599869424929 -6.47604142680908 2.11369526669902e-10 PRRC2B other 1.72109960975436e-21 3.00398371303265e-06 3.69518769931188e-06 6.4053913853061 -6.47604142680908 1.34624180019774e-17 747.207652693106 91.8871803103886 8.13179433920042 3.34773439095423e-15 -714.414173010927 330.528986594632 -2.16142668868888 0.0311353733859597 CHMP2A essential 1.50334821828081e-13 1 4.29547799703337e-11 8.13179433920042 -2.16142668868888 1.60811388524955e-14 271.302276493047 34.2060043797195 7.93142260877157 1.42800664742526e-14 -20.4412203731721 117.310942020167 -0.174248199026977 0.861740935940926 UBE2M essential 1.63014504547747e-10 1 1.81214043558266e-10 7.93142260877157 -0.174248199026977 2.71918283330721e-25 2087.28202412247 191.887084163189 10.8776577288931 6.79859154504743e-25 -167.699370468285 702.408305420292 -0.238749128070091 0.811397358049217 TRIM28 other 3.52623629823279e-21 1 9.73422337419891e-21 10.8776577288931 -0.238749128070091 2.98807144382599e-13 231.862278001299 35.1016267774152 6.60545676334528 9.61141175539739e-11 -256.46745188201 154.47959613071 -1.66020276014319 0.0974618205418411 METTL26 other 2.88558059330276e-09 1 1.10771520480955e-06 6.60545676334528 -1.66020276014319 2.44515681072674e-27 543.980190543508 51.7765628550484 10.5063017038503 1.27055812836197e-23 -394.276134296522 169.482570978174 -2.32635209638929 0.0203682519515325 YIPF2 other 3.25670435620694e-23 1 1.80330315158415e-19 10.5063017038503 -2.32635209638929 8.25299188150434e-27 144.306702671124 14.2512563266084 10.1258934204762 3.50227540027887e-22 -133.245030537917 46.8780975177685 -2.84237282640177 0.00464727472692571 ATG4D other 1.09261359519236e-22 1 4.90913942857089e-18 10.1258934204762 -2.84237282640177 0.0206432925961345 10.5124971529911 7.68963137249692 1.36710027356976 0.172154391494414 -39.4863647715267 22.028655249507 -1.79250001074897 0.0736043656343074 TMEM160 other 1 1 1 1.36710027356976 -1.79250001074897 1.23378139514934e-08 52.1713470398632 21.1393315451594 2.46797524928406 0.0138922701664026 -268.312628607755 60.6919709175339 -4.42089166905337 1.18556850846008e-05 ZC3H4 other 9.48654514730324e-05 0.142469767661648 1 2.46797524928406 -4.42089166905337 1.70446022810859e-05 -0.203468356848442 3.37004172320121 -0.0603756195205698 0.951878487560733 -42.910008835739 9.65423226428971 -4.44468370565932 1.06573943386097e-05 NPAS1 other 0.101500606583866 0.128453573963263 1 -0.0603756195205698 -4.44468370565932 0.0914241909512592 -10.1537213389742 7.38310472728986 -1.37526443332755 0.169616588561897 -78.7949515286268 39.9756656816947 -1.97107290610317 0.0492229226571612 GMFG other 1 1 1 -1.37526443332755 -1.97107290610317 5.31049553542272e-08 38.2790395295316 8.55143980557936 4.47632684083873 9.25861297320739e-06 -76.2795316423596 33.0487388083147 -2.30809206017776 0.0213689242767915 MAP3K10 other 0.000392764249799864 1 0.0836793440518484 4.47632684083873 -2.30809206017776 7.99817246930899e-12 45.0484724714032 27.9990817537148 1.60892678080153 0.108217869445539 -275.235309559678 49.787630718932 -5.52818653117828 5.04754150984543e-08 ARHGEF16 other 7.28873457128128e-08 0.000674603922790842 1 1.60892678080153 -5.52818653117828 1.11032595312038e-21 196.433979536137 35.3765574530142 5.55265954854519 4.41175376539162e-08 -306.859514864234 61.7963350119859 -4.96565880168648 9.18803619430711e-07 LRRC47 other 1.35948309700059e-17 0.0116917760572558 0.000459307684514922 5.55265954854519 -4.96565880168648 1.11641012475542e-09 51.6826915191742 24.0964945910541 2.14482199159215 0.0324109410071586 -164.682163721957 38.6588510313903 -4.25988251922537 2.41161796909678e-05 SESN2 other 9.11437225850322e-06 0.283992132040836 1 2.14482199159215 -4.25988251922537 0.000486107805621178 67.6566886234285 28.9682372001724 2.33554731535496 0.0198780374381672 -71.8848553173325 46.3771923336376 -1.55000446771751 0.121723053968791 SMPDL3B other 1 1 1 2.33554731535496 -1.55000446771751 7.3387501794828e-14 161.168054395177 87.9553828668061 1.83238420596996 0.0674426781533748 -818.740418877384 141.109904214828 -5.80214708126314 1.11434032363556e-08 ATPIF1 other 7.25875780252644e-10 0.000152040593756835 1 1.83238420596996 -5.80214708126314 1.00024266990086e-14 49.7189788110381 11.4684133225044 4.33529708189667 1.73573179644058e-05 -71.8007056821441 18.3991775453391 -3.90238669664518 0.000107238612881966 MED18 essential 1.02154783876975e-10 1 0.153230402989774 4.33529708189667 -3.90238669664518 0.454172981888122 39.7603681084192 31.808897279441 1.24997631194582 0.211846646492293 26.224944991328 50.9249954305391 0.514971965527191 0.60678217088074 THEMIS2 other 1 1 1 1.24997631194582 0.514971965527191 1.38535152527726e-07 294.28005741698 79.5039592211957 3.70145160441928 0.000236245284543599 -536.362085072764 175.515983696386 -3.05591589880829 0.00235403201777111 CLIP1 other 0.000992604367861156 1 1 3.70145160441928 -3.05591589880829 0.00033592608409969 147.713282279589 49.3582658023836 2.99267569227394 0.00289971028991597 -181.549375580854 108.508393362665 -1.67313670357339 0.0949148152307522 HIP1R other 1 1 1 2.99267569227394 -1.67313670357339 2.38232151341321e-55 208.669012573275 12.8687066139678 16.2152280592662 2.24349747798018e-48 -161.748242168425 50.2756546233359 -3.21722796809389 0.00137282995147316 ZNF317 other 3.63494616516588e-51 1 3.43277549105747e-44 16.2152280592662 -3.21722796809389 4.77670907842041e-28 198.10754113444 17.2836264880418 11.4621512604144 2.17103281099051e-27 -26.8349026141281 62.9979919578719 -0.425964412200205 0.67030256955589 PPAN other 6.41368727959509e-24 1 3.15255674483933e-23 11.4621512604144 -0.425964412200205 1.97605141381596e-24 535.506361916869 65.0069628293009 8.23767699043306 1.3196651315166e-15 -1221.52468507587 236.947270548772 -5.15525957419474 3.55310429006354e-07 EIF3G essential 2.53211228166377e-20 0.00459736164091321 1.70461145038e-11 8.23767699043306 -5.15525957419474 0.000139847899820793 9.30522810744283 4.30883181461897 2.15957097138768 0.031242983835035 -47.6715820290694 15.626285266089 -3.05073030584707 0.00239436048973266 ANGPTL6 other 0.745395804943796 1 1 2.15957097138768 -3.05073030584707 0.000439395042775561 35.1497540986356 17.2059420515287 2.0428846030847 0.0415452820114667 -174.651675517549 62.1545105165185 -2.8099597932017 0.00513313402621059 C19orf66 other 1 1 1 2.0428846030847 -2.8099597932017 9.77606657993488e-29 807.64795541326 68.5107347885985 11.7886336777061 1.02938996051512e-28 63.2879186308803 250.266653295844 0.252881947304688 0.800455320090918 DNMT1 other 1.32191972293879e-24 1 1.5041446103047e-24 11.7886336777061 0.252881947304688 1.71779813994177e-20 105.189607055202 12.2755336793229 8.56904553423896 1.12557501633117e-16 -128.183958055702 46.1108865737377 -2.77990660298232 0.00562921303449365 ZNF426 other 2.05414301574237e-16 1 1.48215718150488e-12 8.56904553423896 -2.77990660298232 8.22936473922623e-10 58.9630489889575 11.9419384183423 4.93747722718054 1.05699803107269e-06 -170.815718158781 50.0205321463705 -3.41491205369304 0.000686080039668671 ZNF331 other 6.7661836885918e-06 1 0.0101556370825464 4.93747722718054 -3.41491205369304 2.13650005645357e-20 71.602558520806 15.0928452737724 4.74413917468784 2.69631490655614e-06 -180.977057448899 30.8728885024086 -5.86200599386027 8.0465725240322e-09 ZNF236 essential 2.54905821735476e-16 0.000110358742167102 0.0252509890998982 4.74413917468784 -5.86200599386027 0.00325752228939332 27.4231242378891 8.0733281381897 3.39675580733156 0.000733292115965088 19.0806518332945 36.4597459340837 0.523334744783764 0.600960885463624 SLC7A10 other 1 1 1 3.39675580733156 0.523334744783764 2.31642576179059e-14 257.543069318274 33.1336643944811 7.77285199282612 4.01487917726298e-14 -116.037137656247 148.189029635355 -0.783034600751327 0.43395653431663 LRP3 other 2.33264074212313e-10 1 5.04630163790184e-10 7.77285199282612 -0.783034600751327 1.91649872877329e-05 46.3042151746524 13.837854769879 3.3461989553065 0.000875629607511633 -69.0970204274172 31.2977671403074 -2.20773003127209 0.0276780935136768 C12orf65 other 0.113629209628968 1 1 3.3461989553065 -2.20773003127209 8.18300894284993e-80 467.1705774717 20.3457823751729 22.961544012275 4.38120166755805e-81 284.220335600355 82.8127714035232 3.43208337051576 0.000646670089326141 NOL11 essential 1.27270338088145e-75 1 6.82591219805544e-77 22.961544012275 3.43208337051576 1.1229405570285e-19 284.301424806479 51.0446352435693 5.5696631673413 4.02327177340479e-08 -345.13416334359 83.9045202111463 -4.11341561187713 4.50421719061879e-05 UBE4B other 1.32158874156684e-15 0.521363139814125 0.000419667478683854 5.5696631673413 -4.11341561187713 3.22912542636577e-12 41.2823568177994 67.8641916429625 0.60830838500204 0.543238259349512 -671.189058197092 110.042471198181 -6.09936373555549 2.02879127173315e-09 CASZ1 other 2.99307635769843e-08 2.82286017548951e-05 1 0.60830838500204 -6.09936373555549 0.066987051318731 9.74680665480265 11.8901226219773 0.819739792824925 0.412724787093587 -44.0090717151374 24.8084655890667 -1.77395379642232 0.0766321606909213 HABP4 other 1 1 1 0.819739792824925 -1.77395379642232 0.109925798539331 48.6286070457824 23.8962201990693 2.03499158614534 0.0423386970089768 6.74576460779312 50.0303069974492 0.13483356414617 0.892793616047979 FBP2 other 1 1 1 2.03499158614534 0.13483356414617 1.22237197364731e-09 20.4654245744159 12.1216719512351 1.68833347880947 0.0919224600593966 -135.547046228867 25.2915879040918 -5.35937271882154 1.23723259213956e-07 SLC35D2 other 9.95744209733095e-06 0.00163054883318072 1 1.68833347880947 -5.35937271882154 2.90199551769819e-21 17.3738941360182 5.80599553949189 2.99240569818603 0.00289490364762703 -82.4178446336986 11.7274322850809 -7.02778260664502 6.38083641108165e-12 POLN other 3.52360295758914e-17 9.2917739818171e-08 1 2.99240569818603 -7.02778260664502 3.27051350846855e-29 76.8934399173424 12.3864213801699 6.20788180518752 1.06487122357275e-09 -212.336725974408 30.9340261734979 -6.86418007095122 1.82563930997814e-11 PPIL4 essential 4.44397375530707e-25 2.64060469795239e-07 1.18434977485761e-05 6.20788180518752 -6.86418007095122 3.28828483935138e-06 15.5849201957528 3.11780907294761 4.99867690134682 7.78789250743992e-07 9.93894398356041 7.79837499685179 1.27448910671425 0.203032271713025 ULBP2 other 0.0209266447176322 1 0.00754568905045853 4.99867690134682 1.27448910671425 0.519185687727759 -107.491741818185 113.558820402014 -0.946573251092682 0.344276539303162 36.3002702009152 245.451011882781 0.147892118767272 0.882482707006169 AKAP12 other 1 1 1 -0.946573251092682 0.147892118767272 0.263860133269195 -109.078197938584 95.8098409210421 -1.13848636935403 0.255419488553164 -326.559204839459 209.377232725471 -1.55966912251454 0.119420699885873 SYNE1 other 1 1 1 -1.13848636935403 -1.55966912251454 3.350162058052e-14 9.53734701214782 1.18132357733948 8.07344168447679 4.38627890853192e-15 7.99328567203597 2.93775900945511 2.72087861744608 0.00671853462580837 ULBP3 other 3.35786743078552e-10 1 5.61575288659342e-11 8.07344168447679 2.72087861744608 1.18085778485471e-19 140.570445945714 27.3140863856764 5.14644509652827 3.71149387985548e-07 -360.310130462668 68.1732496550347 -5.28521278193254 1.81918249036424e-07 LATS1 other 1.38951535543854e-15 0.00237876302440029 0.00367140974595304 5.14644509652827 -5.28521278193254 4.8045962177693e-05 100.591324549944 36.2479981433541 2.77508634137874 0.00570922551508138 -434.179511591949 139.189174480282 -3.11934827699878 0.00190889328925565 EPS8L1 other 0.272372559585342 1 1 2.77508634137874 -3.11934827699878 0.383190464315695 7.63342996896848 5.52353724282069 1.38198216711405 0.167551768396254 9.10068331667362 24.504881632789 0.371382463831058 0.710499164719599 LILRB2 other 1 1 1 1.38198216711405 0.371382463831058 3.53519397228099e-60 252.200655849479 14.0424818635449 17.9598348995704 1.09875947155097e-56 -326.973179165414 93.3517957934716 -3.50259120765923 0.000499670009202766 AAR2 other 5.43323961599866e-56 1 1.69417722918444e-52 17.9598348995704 -3.50259120765923 0.0212471462616332 0.314851469222136 2.40524067064794 0.130902272302472 0.895902382269184 -39.7142986258842 14.4464788104145 -2.74906426313754 0.00618087345357304 TTLL9 other 1 1 1 0.130902272302472 -2.74906426313754 2.630690422109e-16 425.921708252268 74.3264950876254 5.73041561760901 1.68694471563232e-08 -2284.75702840488 406.118837487807 -5.62583366617037 3.00078347901638e-08 RBM39 essential 2.83246437748476e-12 0.000404055495449555 0.000178951095434277 5.73041561760901 -5.62583366617037 0.115711112118476 -4.30321885904982 2.0708290108569 -2.07801746860267 0.0381958445196918 -4.26642700042162 12.2097232347009 -0.349428641289437 0.726908453710877 COX4I2 other 1 1 1 -2.07801746860267 -0.349428641289437 7.65807456933749e-08 21.2694663715988 3.91959145083196 5.4264498324396 8.77926921941395e-08 -27.0535858261223 22.4773183674443 -1.20359490326507 0.229286552243878 ZNF341 other 0.000558503378341783 1 0.000899962887682124 5.4264498324396 -1.20359490326507 0.000133631693801087 29.5495465717579 13.3299215040755 2.21678323932541 0.0270623951563979 -272.348071670032 83.7663155547883 -3.25128388262344 0.00122202466346199 GGT7 other 0.715330456917217 1 1 2.21678323932541 -3.25128388262344 3.62363459170151e-05 111.456939694729 24.4088903913807 4.56624360663635 6.17986354689111e-06 115.304695243706 207.832839684193 0.554795360631722 0.579268689632471 ACSS2 other 0.208576407098339 1 0.0565642910446943 4.56624360663635 0.554795360631722 0.0997329632806734 8.9729877651607 4.22578499121213 2.12338956757638 0.0341761621906614 11.2805533280843 9.94406954681714 1.13440008388668 0.257131011719686 C1QL1 other 1 1 1 2.12338956757638 1.13440008388668 0.390678121699747 0.699527626891976 4.35562536323211 0.160603258672571 0.872466061187517 -12.2567725260758 10.2469837682031 -1.19613466785311 0.232169921320559 GFAP other 1 1 1 0.160603258672571 -1.19613466785311 0.00108224820340251 1.29234554510307 3.92008986502657 0.329672428337128 0.741776043032768 -30.0263437482087 9.15661904598328 -3.27919547569038 0.00110848296803128 PYY other 1 1 1 0.329672428337128 -3.27919547569038 1.18612168544153e-08 -1.32914565702588 1.24420153358673 -1.06827199705685 0.285875154111542 -17.5729440902315 2.9312354178657 -5.99506405494607 3.72333648758831e-09 HIGD1B other 9.13076473452888e-05 5.1478850277396e-05 1 -1.06827199705685 -5.99506405494607 3.305246522447e-42 358.288240479579 58.7441524047909 6.09913031020868 2.02695351375114e-09 -938.104106171595 111.092254827131 -8.44437002049664 2.80234690670784e-16 ATP6V1E1 essential 4.8861459341334e-38 4.24387415551835e-12 2.22721652090975e-05 6.09913031020868 -8.44437002049664 5.18541443649014e-22 52.9754026168598 7.80958919814614 6.78337890415993 3.06591951814231e-11 -144.042131868938 26.2490288528731 -5.48752232611346 6.2520778118144e-08 ZNF227 other 6.39154183441774e-18 0.000833026847646151 3.58528628451562e-07 6.78337890415993 -5.48752232611346 1.63804069475185e-05 28.0558075895716 29.6836416969159 0.945160566079955 0.344993448352942 -383.442111617597 93.2804673386928 -4.11063669123091 4.5500641814932e-05 ZNF428 other 0.0977255078488957 0.526624428366023 1 0.945160566079955 -4.11063669123091 7.44866650393735e-19 3.99679567718298 6.15741898100779 0.64910243878334 0.516572606364343 -113.195441448083 13.6647388443854 -8.28376178550917 1.12023497403414e-15 ZNF141 other 8.57713947928386e-15 1.69099469330453e-11 1 0.64910243878334 -8.28376178550917 4.24311564317716e-24 1132.08909352245 224.00163354289 5.0539323111931 5.91744434134659e-07 -2128.14738455575 470.373475537521 -4.52437795758742 7.44027998298363e-06 COX4I1 other 5.40912382192224e-20 0.0905482073929108 0.0057724669549836 5.0539323111931 -4.52437795758742 7.75440291146861e-65 149.066821035021 13.5787287548053 10.9779658852283 1.81335548147483e-25 -178.362032499221 28.5135145523664 -6.2553506749107 8.02486278942017e-10 EMC8 other 1.19696963341429e-60 1.1265302383788e-05 2.60379713584971e-21 10.9779658852283 -6.2553506749107 2.2227847071549e-25 902.186482583715 143.386612579238 6.29198546750763 6.4268985617418e-10 -1076.27719263867 309.192873125522 -3.48092497009701 0.000539579818014053 GSE1 other 2.8871750561235e-21 1 7.2058386674249e-06 6.29198546750763 -3.48092497009701 1.1193859175986e-32 206.292078342779 30.5886206816104 6.74407912962222 3.93813295152255e-11 -294.549628936385 64.140280921433 -4.59227219938724 5.4499957925701e-06 GINS2 essential 1.56960293365676e-28 0.0668387484000797 4.58792488852377e-07 6.74407912962222 -4.59227219938724 1.59026910885838e-56 555.333937361389 65.8566858643437 8.43246103372565 3.24817878954627e-16 -1035.505017039 142.050062519823 -7.28971884045804 1.14100256924475e-12 CHMP1A essential 2.43231660199889e-52 1.67556227293592e-08 4.24374558854221e-12 8.43246103372565 -7.28971884045804 0.000426755133838984 58.2970938336413 18.1264454686838 3.21613489717873 0.00137737411320384 -55.1739094254027 51.623404933712 -1.0687770304235 0.285649452503734 F12 other 1 1 1 3.21613489717873 -1.0687770304235 0.000198029783687323 19.1184306456068 4.63723931754496 4.12280439641586 4.33441048519693e-05 25.9418883196619 13.2066754884589 1.96430118558846 0.050009529280252 PRR7 other 1 1 0.370375375960078 4.12280439641586 1.96430118558846 0.0380306250313334 34.9881590922025 30.6241109069288 1.1425036696914 0.253776625796813 -98.1767198720836 63.0400282569187 -1.55737112730924 0.119997874009664 NFATC1 other 1 1 1 1.1425036696914 -1.55737112730924 0.877174345886514 7.7794626683633 16.196408476912 0.480320231454579 0.631233109412489 48.5405926502783 195.855944837443 0.247838239939901 0.804372613811308 IDO1 other 1 1 1 0.480320231454579 0.247838239939901 3.08320847284648e-12 1160.5248316399 223.733314218999 5.18708997670293 3.02251927877952e-07 -1729.03190388322 493.108369608284 -3.50639334160304 0.000491871817265415 CAP1 essential 2.85936753771782e-08 1 0.00300589542274623 5.18708997670293 -3.50639334160304 0.0069453613294048 637.760110915729 316.917006308915 2.01238841153911 0.0446740950679695 -1191.497213273 698.509421501635 -1.70577114151381 0.0886246727887247 PPT1 other 1 1 1 2.01238841153911 -1.70577114151381 0.532710022899422 15.0360546248955 24.3414282898809 0.617714558317278 0.537024887030892 -32.1065554488793 51.270623424585 -0.626217379550796 0.53143795993785 TRAF3 other 1 1 1 0.617714558317278 -0.626217379550796 4.74077462137541e-31 75.9204950002119 6.08920367109649 12.4680498634957 1.44572638812408e-31 32.3864497428031 22.5647418062986 1.4352679069327 0.151784400593674 HAUS8 essential 6.55080237181654e-27 1 2.13765103748026e-27 12.4680498634957 1.4352679069327 6.90984868410211e-21 221.777095063508 22.5632905038579 9.82911136235152 4.23347351269949e-21 9.9281582432594 65.3718149743679 0.151872152351165 0.879343975103282 MRPS25 essential 8.33535046763237e-17 1 5.88029470913959e-17 9.82911136235152 0.151872152351165 1.96221302445607e-09 307.049016227516 47.6170770822063 6.44829617948672 2.50255718904164e-10 231.46290268324 137.689819435628 1.68104587275933 0.0933290582641836 SH3BP5 other 1.58429079594583e-05 1 2.84765982541048e-06 6.44829617948672 1.68104587275933 8.02286265124439e-20 60.4229462770725 9.43933571533746 6.40118628039625 3.3325674131228e-10 -154.083650584209 27.1099317693912 -5.68366058221433 2.15179317477929e-08 HACL1 other 9.4677802147335e-16 0.000290965473093655 3.77979795996388e-06 6.40118628039625 -5.68366058221433 3.23365591145244e-11 201.129993554587 42.3954974549861 4.7441357131884 2.68772171016851e-06 -377.630890341438 102.256399325047 -3.69298051597773 0.000244316024233682 TBC1D5 other 2.85984528808854e-07 1 0.0251785769808586 4.7441357131884 -3.69298051597773 7.45071803035924e-33 239.767911485494 21.1087827847001 11.3586801252833 5.60655277961659e-27 -218.908076996701 61.0349578821622 -3.58660159017949 0.000365202536369707 CAPN7 other 1.04667686890487e-28 1 8.1216523565526e-23 11.3586801252833 -3.58660159017949 0.4180350394721 2.77581434132552 41.2356021661859 0.0673159647369416 0.946355083954232 132.595579206934 102.724436291625 1.29078906629877 0.197329180539618 RFTN1 other 1 1 1 0.0673159647369416 1.29078906629877 8.10920901034176e-31 194.035941664243 17.8445208312321 10.8736986271234 4.6953923451705e-25 -188.188358184825 51.7034503887915 -3.63976401516177 0.000298921153080423 RBSN other 1.1175300937152e-26 1 6.72896676986384e-21 10.8736986271234 -3.63976401516177 0.232549612039017 -3.45164684923956 29.9151568344322 -0.115381205197852 0.908185708919486 -124.245591682299 74.0384643994309 -1.67812221242198 0.093899699994786 GALNT15 other 1 1 1 -0.115381205197852 -1.67812221242198 0.0010020647338587 25.4765412928081 43.4866100731013 0.585847948368058 0.558224292254855 -440.775403221998 127.109337714608 -3.46768704130651 0.000567130004796553 SLC6A6 other 1 1 1 0.585847948368058 -3.46768704130651 0.412382241858776 15.8810242446882 21.840746349499 0.727128276230017 0.467459595397728 -70.6316264151589 77.1328440444279 -0.915714016385492 0.360221900089662 KCNC3 other 1 1 1 0.727128276230017 -0.915714016385492 0.000391460269158441 2.61024738170005 1.12666015377255 2.31680100956778 0.0208844005622338 -10.4177123752032 3.97891631272038 -2.61822857190999 0.0090845649485653 NAPSA other 1 1 1 2.31680100956778 -2.61822857190999 0.0104987098112295 -32.5670890028835 10.7561327440583 -3.0277693458993 0.00258022691903866 -32.3396314026735 37.9863900341322 -0.851347847837481 0.394950060559388 NAPSB other 1 1 1 -3.0277693458993 -0.851347847837481 3.92971219263933e-15 219.005256863918 31.5643253193047 6.93837915584955 1.1292316724582e-11 -332.659250783149 111.472664132532 -2.98422266455967 0.00297047151308885 NR1H2 other 4.07393263010919e-11 1 1.33780076236123e-07 6.93837915584955 -2.98422266455967 0.415134661305813 2.92786511985708 2.27505353742109 1.28694339350624 0.198661349587415 -0.13027663073752 8.08232322464297 -0.0161187108108109 0.987145596118068 LRRC4B other 1 1 1 1.28694339350624 -0.0161187108108109 0.152721148864473 28.5191941698545 29.4699581886571 0.96773785654136 0.333605340710443 -80.8173354192419 68.8684562094854 -1.17350293396167 0.241107709404248 PDLIM4 other 1 1 1 0.96773785654136 -1.17350293396167 1.27206512287504e-17 101.443322865069 22.2607336313159 4.55705209653832 6.41313632634831e-06 -287.375431981213 52.0256334343245 -5.52372768981249 5.15407121316209e-08 KIF3A other 1.42153277481285e-13 0.000688583914078455 0.0586032397501709 4.55705209653832 -5.52372768981249 4.447499478995e-10 353.024466037635 61.9496615912282 5.69856972532069 2.01221022082095e-08 -227.409789755987 164.855233389525 -1.37945144403549 0.168340661173839 MGAT1 other 3.71502857043463e-06 1 0.000212690620340774 5.69856972532069 -1.37945144403549 0.51089881616049 -6.4904401073313 19.6742037893587 -0.329895947852376 0.741608442932689 49.8220912488864 53.2069239583764 0.936383604657583 0.349500581297255 GFPT2 other 1 1 1 -0.329895947852376 0.936383604657583 4.43101464012231e-38 393.639915944512 31.1368021097198 12.6422718221802 2.97068632790894e-32 -75.7549706637778 69.3589686173213 -1.09221593362706 0.275227962310833 TUBG1 essential 6.4342763589216e-34 1 4.40136886342988e-28 12.6422718221802 -1.09221593362706 4.44150814310175e-54 721.494836278918 50.7470442485489 14.2174750660389 3.90956387720444e-39 -443.166695395357 113.1335884349 -3.91719825673493 0.000101210400063538 PSME3 other 6.76397275112966e-50 1 5.89953189070149e-35 14.2174750660389 -3.91719825673493 3.63882877901109e-13 986.196738353634 275.244537429889 3.5829838715867 0.000370708029943822 -2961.75933746471 606.680890067025 -4.88190642882702 1.38909355329748e-06 RPL27 essential 3.49873387101916e-09 0.0175220260812945 1 3.5829838715867 -4.88190642882702 4.74639861190289e-28 130.907923035654 11.9178995416889 10.9841438567038 1.87049005759651e-25 1.07529489313149 26.5023284037227 0.0405736008078612 0.967650938571224 PSMC3IP other 6.3734640560632e-24 1 2.68564962469707e-21 10.9841438567038 0.0405736008078612 0.190079207428269 -111.309333822958 224.404339454023 -0.496021307314175 0.620083466357946 -902.681633491467 499.958515139119 -1.80551306989998 0.0715574774192608 AOC3 other 1 1 1 -0.496021307314175 -1.80551306989998 1.86022092278847e-26 1340.24606911124 151.41022378156 8.85175409980786 1.27349897795381e-17 -1021.76485771519 345.147020180406 -2.96037571809578 0.00320942446103648 ACLY other 2.45121310995837e-22 1 1.70228608383086e-13 8.85175409980786 -2.96037571809578 6.82220067664543e-56 359.783077126897 28.8741890843994 12.4603699198356 1.83645415821609e-31 -448.46899449208 64.2891974860843 -6.97580638783294 9.03409646388676e-12 VPS25 essential 1.04188648733729e-51 1.31220251137955e-07 2.71372830959592e-27 12.4603699198356 -6.97580638783294 1.31453311513197e-13 4.52631863254222 30.9193101162215 0.146391320360267 0.883667519399647 -499.250597889426 69.0368189407628 -7.23165704256751 1.65613119438807e-12 RAMP2 other 1.28850535945236e-09 2.42788833097291e-08 1 0.146391320360267 -7.23165704256751 0.0104908371813056 3.96003772833349 2.12497033859534 1.86357317860313 0.0629303225033649 -6.74793959673034 4.73281565269667 -1.42577697757687 0.154517014312007 AOC2 other 1 1 1 1.86357317860313 -1.42577697757687 2.24845818912923e-20 293.507741003357 53.0058406557952 5.5372716925539 4.79079429054502e-08 -719.668478968719 125.523184999496 -5.73335100580509 1.63529842085942e-08 NDUFA2 other 2.68173608217444e-16 0.000222106231521126 0.000498146790330871 5.5372716925539 -5.73335100580509 4.1578430751412e-21 327.175773752298 88.9499680662267 3.67820001361555 0.000258228655066626 -1591.59924146839 211.503979390172 -7.52515033550404 2.19585158309823e-13 ANKHD1 other 5.03390061107345e-17 3.24876241719383e-09 1 3.67820001361555 -7.52515033550404 0.0495842894695448 238.706776654908 97.5581070563089 2.44681640365501 0.0147295559300607 146.824892713108 230.485896211237 0.637023328223713 0.524379112359692 DIAPH1 other 1 1 1 2.44681640365501 0.637023328223713 3.16203645796577e-35 485.766087283191 87.5861457059456 5.54615211535922 4.55186880525803e-08 -1950.943511021 203.585279048848 -9.58293016143318 3.27741415312917e-20 NDFIP1 other 4.51823389478729e-31 5.05016746855674e-16 0.000473621949187098 5.54615211535922 -9.58293016143318 3.55266042887391e-24 225.311281565818 32.7587599935801 6.87789408420749 1.67399518365354e-11 -433.336298927647 78.0376543638833 -5.55291291697511 4.39868345618282e-08 UBE2D2 other 4.53390523932889e-20 0.000589203648955689 1.97364032152752e-07 6.87789408420749 -5.55291291697511 1.72556018815301e-18 227.168081878745 37.8598822040101 6.00023213634519 3.59089906275414e-09 -605.078827714741 124.845626065432 -4.84661615135494 1.63911062771205e-06 EXOC4 essential 1.97145251496482e-14 0.0206052597009682 3.90761636008905e-05 6.00023213634519 -4.84661615135494 2.16268059183233e-10 169.680658691131 38.306611065667 4.4295398097278 1.15111188086648e-05 -199.981710991867 74.8524880553221 -2.67167753788043 0.00778307952189057 ACAP3 other 1.83871103917585e-06 1 0.103254735713723 4.4295398097278 -2.67167753788043 1.87400313808124e-08 67.2428223170421 15.6003913001203 4.31032921055791 1.9509355820107e-05 -53.7321151936052 29.1776515339783 -1.84155037738498 0.0661113811178298 C1orf159 other 0.000142686598933506 1 0.171662821861122 4.31032921055791 -1.84155037738498 3.14030932608645e-31 1037.95764498428 82.640004433055 12.559990190043 1.35580310099129e-31 -47.4383516167226 800.489658832842 -0.05926166702252 0.95276765766027 ANO1 other 4.3480722928993e-27 1 2.00496162574593e-27 12.559990190043 -0.05926166702252 9.18029280929554e-100 765.51037968523 28.2830571617871 27.0660408210574 1.76243056033533e-99 140.747782430303 242.03375241865 0.581521300330248 0.561155491113999 PPFIA1 other 1.43341091924341e-95 1 2.75379775052395e-95 27.0660408210574 0.581521300330248 0.0080268957056213 -21.6764783044265 12.7236602433513 -1.7036354232858 0.0890224326338172 -174.861296039836 57.7091908464868 -3.03004241568709 0.0025618600533224 TMEM204 other 1 1 1 -1.7036354232858 -3.03004241568709 0.000100496788184871 39.9978690221255 9.25302941040674 4.32267825466333 1.83397266545966e-05 52.9633744334859 42.1185168557172 1.25748431776264 0.209118862148146 KREMEN2 other 0.545999050208406 1 0.161646350733615 4.32267825466333 1.25748431776264 3.64966006051109e-22 206.118040593661 20.7000857865633 9.95735199935527 1.45803379092869e-21 46.2527901710162 94.1478208368052 0.491278393487091 0.623428430569867 THOC6 other 4.50988493677356e-18 1 2.03337392482915e-17 9.95735199935527 0.491278393487091 1.81150898839395e-18 462.828758385722 55.6956951880045 8.30995567652785 7.92596684506789e-16 -377.927330336189 254.870126606419 -1.48282317495687 0.138710204641401 TRAF7 other 2.06838096294821e-14 1 1.02831493847911e-11 8.30995567652785 -1.48282317495687 0.152255881449556 14.4990946667418 14.4384264177371 1.00420186017848 0.315730258542231 59.8859761550658 31.4885888762275 1.90183105347973 0.0577241395390329 BARX1 other 1 1 1 1.00420186017848 1.90183105347973 4.17999841035518e-13 21.9644764441267 104.903813153479 0.209377293197071 0.834232534806224 -1641.10653498529 226.379013031892 -7.24937578358507 1.45434881342677e-12 NINJ1 other 4.00569247664336e-09 2.13323883953439e-08 1 0.209377293197071 -7.24937578358507 0.983102482861431 -8.61028425089788 64.7937608011129 -0.132887551894503 0.894331815281904 -18.9380144057332 107.070779605578 -0.176873788306165 0.859673845955863 CA6 other 1 1 1 -0.132887551894503 -0.176873788306165 4.86522364029183e-10 42.6081792369343 11.849303404728 3.59583831906383 0.0003528316925252 -63.7033973781266 19.7254008298904 -3.22951091982857 0.00131500303713317 NPHP4 other 4.05419085945518e-06 1 1 3.59583831906383 -3.22951091982857 0.00907088183383556 166.360737729178 133.901212606918 1.24241397437936 0.214625125276917 982.494574848035 318.984312541607 3.08007176597401 0.00217525065752953 MAP1B other 1 1 1 1.24241397437936 3.08007176597401 0.724513456344916 27.9903477240184 43.6261692525094 0.641595359015126 0.521406179798894 -19.0513824231653 98.8588836364659 -0.192712902698993 0.84725573992613 CKMT2 other 1 1 1 0.641595359015126 -0.192712902698993 3.24488601238088e-17 40.6830608314133 6.82513636581765 5.96076893571921 4.51693895713812e-09 -60.3044575786044 15.4660694109091 -3.89914567020294 0.000108597760948738 ZCCHC9 essential 3.5875459752883e-13 1 4.89816860512058e-05 5.96076893571921 -3.89914567020294 2.53636235022302e-06 222.041500256022 44.3565368218919 5.00583490428032 7.62224824049131e-07 52.8984733091427 175.93651744123 0.30066795727506 0.763787647782711 TNS4 other 0.0163189553613349 1 0.00738900744433227 5.00583490428032 0.30066795727506 3.60331991566542e-72 1504.30396043274 70.2615352808991 21.4100639050751 1.83585546866602e-73 1970.17420754261 404.888372554235 4.86596884744746 1.51074193301929e-06 TOP2A essential 5.582983877332e-68 0.0190247731625119 2.85402091158819e-69 21.4100639050751 4.86596884744746 4.67953807609581e-177 453.72569609816 10.2425267411653 44.2982193324044 6.53771385518369e-176 -184.84151748572 197.459727239128 -0.936097299789505 0.349671405574606 STARD3 other 7.33283616524214e-173 1 1.02445976110728e-171 44.2982193324044 -0.936097299789505 6.36770072221936e-49 536.715173765485 40.2035278721149 13.3499521602369 3.86079237466753e-35 -2150.89473355293 304.809248791633 -7.0565271299339 5.51543303505345e-12 RARA og 9.60121914896235e-45 8.03708901867989e-08 5.77111244165302e-31 13.3499521602369 -7.0565271299339 1.79084820365288e-56 2188.18795019642 119.936806487047 18.2445073725782 1.69533380488049e-57 3283.45993337579 2306.85792623761 1.42334727077492 0.155253005402894 PPP1R1B other 2.73856507302599e-52 1 2.61623912769157e-53 18.2445073725782 1.42334727077492 5.16844092238673e-05 44.4272900349233 10.4376244032656 4.25645609752189 2.44836584546403e-05 157.006748452046 85.2758075191042 1.84116401849226 0.0661448552674325 KHDRBS3 other 0.291396699204164 1 0.213840272942828 4.25645609752189 1.84116401849226 1.51152139340368e-11 53.4714964804809 8.40978813616986 6.35824537011867 4.57799233101813e-10 -89.6807983460145 49.3902334080737 -1.81575975972923 0.0700013043959776 CLUHP3 other 1.35674160271914e-07 1 5.16443314862156e-06 6.35824537011867 -1.81575975972923 4.63577840614083e-19 1095.04731079728 287.096257439105 3.8142165995652 0.000152510272795063 -4532.4349125532 686.053384701196 -6.60653385527317 9.50215019610186e-11 MCCC2 other 5.36915854999231e-15 1.35909254254845e-06 1 3.8142165995652 -6.60653385527317 1.00934281692671e-36 148.060356742888 10.8420926974704 13.6560681479354 9.79373709832689e-37 -26.5415969854654 54.6026641866588 -0.486086116507669 0.627101134037017 ZNF304 other 1.454261130628e-32 1 1.469256439491e-32 13.6560681479354 -0.486086116507669 2.33467224515259e-18 23.4996368422095 2.52002927218136 9.32514439479824 2.7240321684051e-19 23.4161909909474 11.3336046795207 2.06608503235157 0.0392906864225597 ZSCAN5A other 2.65965862167783e-14 1 3.71694189378875e-15 9.32514439479824 2.06608503235157 3.0307741646569e-05 6.87761680368742 3.67308828829253 1.87243438324336 0.061724156525614 -49.0255008797305 13.4671226256609 -3.64038423369777 0.000300291327004487 ZNF132 other 0.175754593808453 1 1 1.87243438324336 -3.64038423369777 6.33415858519388e-55 466.005006607751 27.7308107373935 16.8045936709441 3.22751036746485e-51 -149.660143829504 89.3467807712193 -1.67504797081299 0.0945080843565618 SELENOS other 9.65705817898659e-51 1 4.9532601609483e-47 16.8045936709441 -1.67504797081299 2.26401284763171e-15 428.022376113281 55.1423563182752 7.76213431364424 4.24585788990688e-14 -255.13806794707 180.674159978611 -1.41214475815066 0.158486560801114 CHSY1 other 2.36498782063608e-11 1 5.33534502445698e-10 7.76213431364424 -1.41214475815066 7.99980073874375e-31 146.339688906165 11.7654467983797 12.4380902326904 2.21237202488501e-31 183.519203685498 37.9074671031086 4.84124152073585 1.69031011088622e-06 SNRPA1 essential 1.10269253382844e-26 0.0212370562331745 3.2687796667676e-27 12.4380902326904 4.84124152073585 1.17967301398663e-24 167.440239589958 23.2559486642755 7.19988859655379 2.10824887558923e-12 -203.781549222666 47.0368953828371 -4.33237669204294 1.76912968422407e-05 LLGL1 other 1.5172954305896e-20 0.210384902047926 2.54549969238643e-08 7.19988859655379 -4.33237669204294 0.0114035839830445 32.1253912350808 14.8643156330919 2.16124253736654 0.0311106151253028 70.7423696048784 24.4178319600143 2.89716014594266 0.00391664801470147 LIN28A other 1 1 1 2.16124253736654 2.89716014594266 1.06348606023555e-27 30.7494797109019 3.49035514588749 8.80984267378422 3.94922860589201e-17 -75.7793843608498 15.4504267405257 -4.90467905084357 1.36741376976059e-06 THAP1 essential 1.42273165138312e-23 0.0172608640156879 5.24299589718223e-13 8.80984267378422 -4.90467905084357 2.01667456764174e-13 283.085521412812 38.2532145687982 7.40030673510287 5.24879977181965e-13 -178.484005919774 174.78525355445 -1.02116169579587 0.307635943186953 RHPN2 other 1.96081268211807e-09 1 6.42138164084416e-09 7.40030673510287 -1.02116169579587 4.69390623951402e-07 94.4890710385382 17.7460885198279 5.3245012799843 1.5133164907925e-07 -3.03535626955111 71.793215807826 -0.0422791518028119 0.966292519420564 C19orf12 other 0.00322142785217848 1 0.00152814699240226 5.3245012799843 -0.0422791518028119 1.28867713349608e-14 27.5853975689772 3.50360601339759 7.87343024971762 1.90882986358474e-14 -11.4692283814261 16.0085543740444 -0.716443728361994 0.474027701146924 FAAP24 other 1.31058464476551e-10 1 2.41428801146197e-10 7.87343024971762 -0.716443728361994 1.45871512518159e-48 200.060989926595 22.0359829368612 9.07883213105682 2.00266332059603e-18 -443.126814462161 46.554443459874 -9.5184644371079 5.65114654423074e-20 ACTR10 essential 2.196970850036e-44 8.70333079276977e-16 2.70539787979318e-14 9.07883213105682 -9.5184644371079 0.165932585948987 5.26208082545149 9.85533459952955 0.533932234599389 0.593607328914767 -37.8568644310691 24.011970404065 -1.5765830039779 0.11547496659307 ABHD12B other 1 1 1 0.533932234599389 -1.5765830039779 2.47846311266768e-09 103.140232186854 16.2453109713203 6.34892322892058 4.59505567044856e-10 48.4001918585378 36.4805038150336 1.32674132199326 0.185153994502577 GCH1 other 1.98747957004821e-05 1 5.18322279626598e-06 6.34892322892058 1.32674132199326 0.0014241710805608 426.977025601619 212.555257293378 2.00878129780759 0.0450566902764382 -1015.09116077815 469.146554496059 -2.16369735863993 0.030924606773991 LGALS3 other 1 1 1 2.00878129780759 -2.16369735863993 0.0654598808417985 14.1213296610391 10.7525068563367 1.31330580391279 0.189646061144164 -56.5807134568686 37.578746827674 -1.50565727261562 0.132748663676254 PODNL1 other 1 1 1 1.31330580391279 -1.50565727261562 7.44090396957251e-18 708.818647635166 93.5581988937124 7.57623229194937 1.54744878874036e-13 -1059.49247409439 348.1284690169 -3.04339509229552 0.00245270183627588 DNAJB1 other 8.37176105616603e-14 1 1.91914598779579e-09 7.57623229194937 -3.04339509229552 1.32764697547592e-18 147.790177728994 15.8247909538703 9.33915513701298 2.59452001344205e-19 68.5511507034079 58.3661741081012 1.17450135718067 0.240716778312802 ZSWIM4 other 1.52059999130882e-14 1 3.54177927034974e-15 9.33915513701298 1.17450135718067 2.57222779109069e-11 51.3464276555255 12.577924316558 4.08226559194122 5.13721086727502e-05 -169.357460845952 38.6818057336741 -4.37822013822172 1.43820397629713e-05 FBXW9 other 2.28568161516318e-07 0.171951667406084 0.435738225762267 4.08226559194122 -4.37822013822172 8.37330627969466e-11 21.6801388770267 9.54033745626482 2.27247086137295 0.0234562360706367 -189.158552104669 33.1310578591084 -5.70940272746725 1.88646409365401e-08 RFX1 other 7.2504459075876e-07 0.000255597020049182 1 2.27247086137295 -5.70940272746725 1.78491990377493e-22 24.2102376086709 4.18353433037536 5.78702974489485 1.23421831347277e-08 -104.897240267836 15.0631848660188 -6.96381550122745 9.96017210205085e-12 ZNF20 other 2.21829845641148e-18 1.44611738749676e-07 0.000131641725315005 5.78702974489485 -6.96381550122745 8.37628476427954e-34 111.400664972573 8.50381280683192 13.1000843390007 3.31950496792976e-34 43.3003323875985 31.3643965543105 1.38055684612391 0.167991757391627 C19orf57 other 1.1847417170597e-29 1 4.94971385768007e-30 13.1000843390007 1.38055684612391 1.06111374177833e-38 228.141921894025 16.5189715514858 13.8109034925666 2.68472029859517e-37 -6.50062353709375 57.7318627256681 -0.112600273578277 0.910389942155515 DCAF15 other 1.54445105115835e-34 1 4.03325530457952e-33 13.8109034925666 -0.112600273578277 2.03075356170058e-34 361.847950703863 29.5728949323443 12.2357973925679 1.63324038250667e-30 -227.161518942233 109.070927893914 -2.08269539215048 0.03775519058689 CC2D1A other 2.88529466046419e-30 1 2.40559975939407e-26 12.2357973925679 -2.08269539215048 0.0931292011160057 -5.99861387648193 12.754455947359 -0.470315151131479 0.638320118755543 75.1180843626545 39.6895862072351 1.89263964533248 0.0589413326534879 RTBDN other 1 1 1 -0.470315151131479 1.89263964533248 0.000238604136711398 -143.345791164586 50.8661687234655 -2.81809687582108 0.00500667833528659 -526.202661764535 146.276074837447 -3.59732555272139 0.000350812568384897 MATN3 other 1 1 1 -2.81809687582108 -3.59732555272139 1.62474440106229e-09 79.0397591460425 19.014102860919 4.15690183881873 3.74387644011433e-05 -122.804999814898 41.2042262320622 -2.98039815438496 0.00300672872094964 TRIM21 other 1.31636791374067e-05 1 0.321757144862239 4.15690183881873 -2.98039815438496 2.56834497652906e-06 -25.3927674223408 18.7614758368884 -1.35345255581728 0.176480518904764 -198.878290276772 38.8713094229138 -5.11632597999226 4.34409602598026e-07 SPATA6 other 0.0165118898541053 0.00560258064470674 1 -1.35345255581728 -5.11632597999226 3.68104784132498e-20 416.191712668156 73.2891507309467 5.67876293444914 2.21075702121189e-08 -806.25494037093 149.382914713214 -5.39723663793 1.01192175582901e-07 LRRC41 other 4.37087620678928e-16 0.00133917725166411 0.000233279080878278 5.67876293444914 -5.39723663793 7.83529518005323e-20 17.2766592368706 3.34922366922889 5.15840712449292 3.52271053024916e-07 -42.5693993490084 7.8673173275801 -5.41091678096862 9.5031303238813e-08 CCT6B other 9.24799890101682e-16 0.00125878464270132 0.00348854023810574 5.15840712449292 -5.41091678096862 2.53192192948836e-30 219.123905085283 48.3383634016034 4.53312627208257 7.22498166895338e-06 -701.83644506875 89.2822371311186 -7.86087431969299 2.22655441840942e-14 DHX30 other 3.47354369506508e-26 3.32446840212711e-10 0.0657762331141516 4.53312627208257 -7.86087431969299 5.40020399372313e-27 509.196131948239 44.5923990916749 11.4188996851551 3.39080496988604e-27 63.3129956952871 113.563459564421 0.557512037218022 0.577409090255267 RAF1 og 7.16445063847248e-23 1 4.91734536732873e-23 11.4188996851551 0.557512037218022 1.22429249597211e-10 46.2837740743334 8.49237568075015 5.45003845970284 7.62834920476947e-08 119.641180362091 22.9289269375468 5.21791450110013 2.57265683592043e-07 SLC6A11 other 1.05044296154407e-06 0.00334471115238015 0.000784804566186683 5.45003845970284 5.21791450110013 0.64045253196169 18.0897142744067 33.5138637935147 0.539768090777621 0.589579481657109 -53.3246855435364 85.5061895697977 -0.623635386067673 0.533130396149905 PPARG other 1 1 1 0.539768090777621 -0.623635386067673 7.6530459954873e-10 917.704252881715 140.036587156567 6.55331775442144 1.32928481044151e-10 864.331301575313 348.512062703581 2.48006136393176 0.0134437574728516 NUP210 other 6.30151807268424e-06 1 1.52575310542476e-06 6.55331775442144 2.48006136393176 0.0582958571669155 -3.34118346404325 1.43204634760592 -2.33315316199717 0.0200070313262072 -7.3088385242418 15.679824054448 -0.466130136337114 0.641310668499116 FCRLA other 1 1 1 -2.33315316199717 -0.466130136337114 0.000647679803328365 43.5118608639538 11.3161617608784 3.84510771261511 0.000134972382051955 -61.8439386308929 103.619262103015 -0.596838245860209 0.550867386835601 HSD17B7 other 1 1 1 3.84510771261511 -0.596838245860209 1.47833063633264e-20 260.063070900391 45.953380421109 5.6592805255504 2.50520199680081e-08 -473.625039445964 100.50032192791 -4.71267186373491 3.13708571282164e-06 ENOSF1 other 1.76897043943563e-16 0.0389280966104038 0.000263822822283093 5.6592805255504 -4.71267186373491 0.00488012702521512 60.5257582727471 22.3115119041575 2.71275915916163 0.00688866942756115 145.669134682102 50.6337122942281 2.8769199033962 0.00417695816716324 EMILIN2 other 1 1 1 2.71275915916163 2.8769199033962 1.10798585350283e-23 190.538905736789 86.5614631476197 2.20119784033513 0.0281428028605962 -1678.28856655639 191.694568500351 -8.75501366411074 2.59949780293208e-17 ARFIP2 other 1.40337488204668e-19 3.96215455122908e-13 1 2.20119784033513 -8.75501366411074 5.3738232418738e-06 11.2215281114848 18.5984749724229 0.603357432699384 0.546521030389566 -182.881931763576 42.4366464454069 -4.30952836951541 1.94024159110232e-05 TRIM5 other 0.0334507916087865 0.230073847872913 1 0.603357432699384 -4.30952836951541 0.350524064576306 41.3315353247136 63.4582351126075 0.651318701999358 0.515114306205065 -133.673533799006 142.323815785541 -0.939221120943178 0.348031768922269 TRIM22 other 1 1 1 0.651318701999358 -0.939221120943178 5.34597662977782e-43 89.6705968365362 10.0971199139167 8.88080933979446 1.00519675322241e-17 -175.651221348705 22.3543265984026 -7.85759394609797 2.16361257426276e-14 RRP8 other 7.92754874429752e-39 3.23178810217629e-10 1.3463605312661e-13 8.88080933979446 -7.85759394609797 6.94067803399895e-27 114.455319195387 24.7859979892181 4.61774100220517 4.85023268892242e-06 -427.761795475702 54.6200319679288 -7.83159181830706 2.55302380041338e-14 TIMM10B other 9.1963983950486e-23 3.8093668125968e-10 0.0446609425995977 4.61774100220517 -7.83159181830706 2.8377811896506e-26 435.093148957009 39.2751608446373 11.078074273919 7.74747801414372e-26 -699.143092256076 359.622583740378 -1.94410230020707 0.0524030639602602 EFR3A other 3.73111470815261e-22 1 1.11493956101542e-21 11.078074273919 -1.94410230020707 4.65628602043191e-11 165.278274864133 25.4286638936252 6.49968380389686 1.8273681129937e-10 -171.728562329178 92.28573360745 -1.86083542511185 0.0633086987330114 PTCD3 essential 4.08449409712288e-07 1 2.0879508059066e-06 6.49968380389686 -1.86083542511185 3.29575414174374e-12 350.777097535529 48.2616280684707 7.26824004026278 1.27802898494614e-12 -119.313262360341 175.151151079757 -0.68120170278533 0.496034805133292 IMMT other 3.05396330749347e-08 1 1.54986575004419e-08 7.26824004026278 -0.68120170278533 1.40006303441387e-05 78.445501445938 18.6909985170047 4.19696686480231 3.16108578531542e-05 -106.844748276657 67.939656051191 -1.57264187790636 0.116385301724809 MRPL35 essential 0.0840737852165529 1 0.273686807292609 4.19696686480231 -1.57264187790636 0.00822855847036025 1.63664396840556 16.1547614655033 0.10131031472674 0.919341252142992 -91.1850574862875 31.5016710355367 -2.89461017428005 0.00394782937904895 IQCA1 other 1 1 1 0.10131031472674 -2.89461017428005 1.31176884977957e-08 63.7396072605665 15.8316472749892 4.02608813558286 6.47190409004098e-05 -87.9946733686233 30.7083323112475 -2.86549827834166 0.00432366613619489 ILKAP other 0.000100638906155088 1 0.544351853013347 4.02608813558286 -2.86549827834166 2.63571605821032e-08 -28.2905553619481 48.0070953050373 -0.589299460469119 0.555903706103822 -538.974087574839 93.1184108841148 -5.78805074590017 1.20047581973368e-08 PER2 other 0.000198864776591968 0.000163696882778885 1 -0.589299460469119 -5.78805074590017 0.12090440946309 -40.6205129814587 88.4649989728783 -0.459170445408722 0.64629418324173 -349.846666776039 171.389113433165 -2.04124205889229 0.0417061453497954 RAMP1 other 1 1 1 -0.459170445408722 -2.04124205889229 2.85132935566154e-12 49.0993993811253 10.4384805690471 4.70369217592051 3.23944996139835e-06 -75.9260154018267 20.2011531826244 -3.75849906762416 0.000189314806919046 SCLY other 2.64802957260287e-08 1 0.0301819552903484 4.70369217592051 -3.75849906762416 0.00497910114592987 -22.3485082547454 25.0694667934961 -0.891463246459771 0.373075544071998 -164.06332093214 50.4042426071997 -3.25495062411086 0.0012047613911074 PTPRE other 1 1 1 -0.891463246459771 -3.25495062411086 2.74181452688117e-13 881.983116755534 121.225522029845 7.275556351396 1.21648197745456e-12 -126.771595259575 283.975841265734 -0.446416831426682 0.655474476943931 RAN essential 2.65215719185215e-09 1 1.47607923144336e-08 7.275556351396 -0.446416831426682 0.0163052644462439 75.1831973096814 42.560806119324 1.76648903450975 0.0778766603019338 -379.465751538867 197.668229316828 -1.91971037961113 0.055419107197695 PRKAA1 other 1 1 1 1.76648903450975 -1.91971037961113 0.735986929494037 6.28617229975286 8.53436988723079 0.736571344201789 0.461702932303726 15.6075881156943 39.5908871186259 0.394221732615625 0.693572974987476 CARD6 other 1 1 1 0.736571344201789 0.394221732615625 2.53712932492261e-14 193.77703458825 28.9332969947703 6.69737135810257 5.30328998370049e-11 -76.888666673894 53.608829891407 -1.43425377553742 0.152074424251905 RAP1GAP2 other 2.55235210087215e-10 1 6.15340736808768e-07 6.69737135810257 -1.43425377553742 2.71171410409585e-21 593.645050312299 67.0017101333101 8.86014773550036 1.17089826049645e-17 -116.00107488132 124.090573995531 -0.934809721208131 0.350306531263002 CLUH other 3.29391912224522e-17 1 1.56595933358795e-13 8.86014773550036 -0.934809721208131 1.12246138037747e-41 150.926688160782 25.521215814474 5.91377343689033 5.93560062984084e-09 -475.972291264775 46.8297056860388 -10.1638967038538 2.52568917777844e-22 INPP5K other 1.65529379764265e-37 3.91608107014546e-18 6.41163580035407e-05 5.91377343689033 -10.1638967038538 1.25704213374929e-36 428.771375843867 39.12327797812 10.9594951650948 2.18467130154902e-25 -249.982935041034 74.1838895584107 -3.36977390278523 0.000805747369979473 MYBBP1A essential 1.80976355995885e-32 1 3.135221784853e-21 10.9594951650948 -3.36977390278523 6.05554155025881e-32 674.839702784694 63.8806655378741 10.5640681276965 7.3825812215467e-24 -259.154728678218 117.316965946672 -2.20901321975902 0.0275889480172184 RPA1 essential 8.43779159613063e-28 1 1.05002452714059e-19 10.5640681276965 -2.20901321975902 0.230381502076675 -390.811154285115 243.141992012216 -1.60733714094717 0.108561716753828 -50.8745063624012 444.263843585322 -0.114514172370704 0.908872542436962 SERPINF1 other 1 1 1 -1.60733714094717 -0.114514172370704 6.12270069792912e-37 325.047576944429 35.8203402594738 9.07438551922912 2.04518743285854e-18 -395.032746316922 66.7633682533797 -5.91690857803485 5.78356302060818e-09 UBE2G1 other 8.83260802683254e-33 7.95818271635686e-05 2.76243466556203e-14 9.07438551922912 -5.91690857803485 2.53837176375262e-15 67.306333234685 11.5893471846783 5.80760349674117 1.08275221028769e-08 -185.335593516367 38.0640695741342 -4.86904305267214 1.47484142974756e-06 EEFSEC essential 2.64726791241761e-11 0.018584476856249 0.000115735383757651 5.80760349674117 -4.86904305267214 2.27914213180445e-16 143.758538260763 62.0048000183897 2.31850660300697 0.0207929545748653 -750.198798135568 120.139596939087 -6.24439250046704 8.59954352487858e-10 TBC1D14 other 2.45896644600382e-12 1.20642996110522e-05 1 2.31850660300697 -6.24439250046704 1.04707856054054e-41 68.9056264837092 13.3451345269126 5.16335195758047 3.40148751578289e-07 -248.845390078345 25.6899317357348 -9.68649479641082 1.38408203305332e-20 TMEM128 other 1.54454558465336e-37 2.13563857700127e-16 0.00337223472314716 5.16335195758047 -9.68649479641082 6.5114619442254e-35 75.6564630068173 6.76802744580153 11.1785100773712 3.23127584755223e-26 -8.41220452661104 15.4687357842766 -0.543819782296736 0.586792036503088 COQ3 other 9.28208900149331e-31 1 4.66046915492458e-22 11.1785100773712 -0.543819782296736 1.05613850627277e-20 48.6214264650266 54.2330808300377 0.896527096024701 0.37037453983729 -990.272530179122 123.952984062968 -7.98909794439527 8.39369175441999e-15 PNISR other 1.26810550448171e-16 1.25821439398756e-10 1 0.896527096024701 -7.98909794439527 0.333190306213201 7.63142639313908 6.13679419409589 1.24355260283637 0.214217163321005 -0.453215924311082 13.7488110476929 -0.0329640085050942 0.973715769868497 POPDC3 other 1 1 1 1.24355260283637 -0.0329640085050942 1.90832408445706e-10 275.214533260554 41.8074805056518 6.58290167051203 1.10963207211023e-10 -80.8208097637073 175.294607535281 -0.461057022232933 0.644946479405604 SEC61G essential 1.6266554495912e-06 1 1.27674266217004e-06 6.58290167051203 -0.461057022232933 0.00923438790781231 46.5121345752288 21.5865949142058 2.15467676861902 0.031637844770516 -163.417699348121 93.0818444002399 -1.75563452143735 0.0797295681020825 LANCL2 other 1 1 1 2.15467676861902 -1.75563452143735 3.37868542876777e-06 68.9340342236398 14.3108677547607 4.81690107161447 1.89490740241538e-06 -29.7232317780952 56.6962798389773 -0.524253652312143 0.600316452302588 FIGNL1 other 0.021474924585248 1 0.0179296138416543 4.81690107161447 -0.524253652312143 0.596292817289826 21.9397689025983 21.76385712154 1.00808274838765 0.313864564300291 7.33698033952549 86.2232643668911 0.0850928156501439 0.932219023869117 DDC other 1 1 1 1.00808274838765 0.0850928156501439 3.63623133827047e-34 663.584095879806 60.6976876631945 10.9326091557551 2.8936579876108e-25 -486.921920544138 158.04977144853 -3.08081382264262 0.00216973345040294 GRSF1 essential 5.15690328393517e-30 1 4.15066301742893e-21 10.9326091557551 -3.08081382264262 0.0172733230875318 -90.4880110515997 31.6618845550387 -2.8579477287368 0.00442905942322082 -80.3785470905052 88.018588846919 -0.913199679107543 0.361546578343025 ENAM other 1 1 1 -2.8579477287368 -0.913199679107543 0.0100804418735591 -1316.26341299477 432.28644968045 -3.04488705109255 0.00244162565029834 -1341.14217711259 1196.87783387243 -1.12053389172845 0.262986261336101 JCHAIN other 1 1 1 -3.04488705109255 -1.12053389172845 2.91267496755729e-13 543.28519620555 84.1009981508209 6.45991377214405 2.34703651330667e-10 -499.611976193128 253.98721773231 -1.96707527510181 0.0496879692878933 ANKRD17 other 2.81364401866034e-09 1 2.67210107039965e-06 6.45991377214405 -1.96707527510181 3.07884148786945e-36 113.927632447503 13.6486192329324 8.34719106036826 5.93414590347968e-16 -277.665321066886 37.7891322638893 -7.34775594019708 7.52723423282704e-13 UTP3 essential 4.42737405955627e-32 1.1071056109642e-08 7.71973040583671e-12 8.34719106036826 -7.34775594019708 3.82331066954005e-07 550.705284855647 130.161514459781 4.23093790158543 2.73570434439174e-05 2055.92315075121 476.72636252796 4.31258539982803 1.91983598656529e-05 ITGB4 other 0.00264726030758953 0.227730944726375 0.237869492744861 4.23093790158543 4.31258539982803 7.4979873618925e-40 829.986672775328 62.1185149238234 13.3613412006573 2.24202800171103e-35 -739.90163860346 228.055526546632 -3.24439249426463 0.00124997901096489 WBP2 other 1.09763036990744e-35 1 3.3540738905597e-31 13.3613412006573 -3.24439249426463 2.03136120024705e-39 167.244575935009 12.6134736206219 13.2592005156754 6.15892322332818e-35 -147.541560746344 46.0595342467265 -3.2032794764274 0.00143884216484433 UNK other 2.96659989684079e-35 1 9.20019951100764e-31 13.2592005156754 -3.2032794764274 1.32348570482672e-17 262.486922085003 33.0225787269393 7.94871061571186 1.10694417627288e-14 723.883050442379 121.111047119897 5.97701917089157 4.13131027531618e-09 TRIM47 other 1.47820118372096e-13 5.7061657522667e-05 1.40814368663673e-10 7.94871061571186 5.97701917089157 2.23263902463448e-07 178.303594849925 53.6455083004484 3.32373763431065 0.000948195358328113 -317.634825126776 104.696722386872 -3.03385643681435 0.0025302344434164 ZRANB2 other 0.00157423377626977 1 1 3.32373763431065 -3.03385643681435 2.3683050499512e-22 1997.59143882961 207.474807557054 9.62811563654684 2.36312931504537e-20 137.092090695625 378.3408405575 0.362350758891412 0.717231959603506 EIF5A essential 2.93646143143449e-18 1 3.2606458288996e-16 9.62811563654684 0.362350758891412 1.76707052357249e-20 113.162087784713 31.4781623064978 3.59493945939003 0.000353856463419171 -380.527741091102 56.6813896977946 -6.7134511542491 4.77505187731642e-11 KDM6B other 2.11200268977384e-16 6.86270455807916e-07 1 3.59493945939003 -6.7134511542491 0.356992508312493 -10.7539566499543 7.60248219312569 -1.41453230363081 0.157774626630326 -4.88463366197911 13.8615241686268 -0.35238791943491 0.724683090024417 CLEC10A other 1 1 1 -1.41453230363081 -0.35238791943491 1.04170560156426e-05 10.9883771850638 6.04559761247089 1.81758328777901 0.0696778090968505 -37.2500967514198 11.2494243905088 -3.31128913429987 0.000990285008488466 SLC52A1 other 0.0632523641269819 1 1 1.81758328777901 -3.31128913429987 0.000114979669107889 3.90085262901162 2.25448972194976 1.7302596640973 0.0841479100351005 -11.1195647185539 4.02141916986219 -2.76508472478758 0.00588290906859084 GUCY2D other 0.61985539616063 1 1 1.7302596640973 -2.76508472478758 4.86529416760627e-42 378.545891028514 36.3808041514993 10.405099608358 3.13813706091669e-23 -367.05064130554 66.3422426313179 -5.53268365293801 4.92656635212535e-08 GPS2 other 7.1879856032215e-38 0.000658632655615638 4.44077775490321e-19 10.405099608358 -5.53268365293801 0.0129761366507224 226.79325607743 92.8199031202477 2.44336880834298 0.0148665154111862 427.005393275519 168.233495756883 2.53817107796768 0.0114201039271524 XAF1 other 1 1 1 2.44336880834298 2.53817107796768 1.38962862458283e-22 -4.72484350964586 16.7332360033047 -0.282362808288411 0.777772922608045 -293.225536315384 30.3637208758446 -9.65710156256427 1.8122347804065e-20 DLG4 other 1.72939282329333e-18 2.79482847834291e-16 1 -0.282362808288411 -9.65710156256427 1.73962992930792e-41 111.003663482076 7.40270328198873 14.9950172597293 1.26073937324922e-42 111.637111472439 83.0589420976414 1.34407095314557 0.179500491793971 RIDA other 2.56386658981401e-37 1 1.91418059040429e-38 14.9950172597293 1.34407095314557 1.58140859464973e-14 208.269661907113 27.0827728632262 7.69011588875778 7.20036717629974e-14 -887.31984583847 339.134625155621 -2.61642362655037 0.00913914009562034 VPS13B other 1.60402273755322e-10 1 8.9961387500689e-10 7.69011588875778 -2.61642362655037 0.116591375495532 -5.35143598815979 9.54602575784951 -0.560593080713135 0.575312313662942 -256.885595819914 126.997743433808 -2.02275716775869 0.0436007432775538 RGS22 other 1 1 1 -0.560593080713135 -2.02275716775869 0.0363018546024032 83.8629647358761 36.2564754981443 2.31304790616419 0.0211019687869444 512.281997066171 406.665985358933 1.25971193930572 0.208327726569369 MATN2 other 1 1 1 2.31304790616419 1.25971193930572 0.321426637166194 17.3131196495521 12.6308614913748 1.37069982608666 0.171032785825229 31.836172842092 29.6041788841502 1.07539455718992 0.282673959261208 REEP2 other 1 1 1 1.37069982608666 1.07539455718992 2.6447267593421e-26 25.354381822497 8.3918009855808 3.02132782534549 0.00263504362123968 -178.720208403882 19.4449945251532 -9.19106498964026 8.18795535199185e-19 PCBD2 other 3.47887357923859e-22 1.25570483278147e-14 1 3.02132782534549 -9.19106498964026 8.64566985022002e-56 221.78100059452 16.0860031188052 13.7872036301702 5.5645379837119e-37 -389.214255259096 58.9518235919106 -6.60224284075421 1.01836266439591e-10 SDF2 other 1.32010732943009e-51 1.45544391995463e-06 8.35404087494668e-33 13.7872036301702 -6.60224284075421 3.39801199326104e-47 619.069878732297 42.494269763061 14.5683143205919 1.75254153833852e-40 -355.159972847409 161.460334729227 -2.19967321040812 0.0282753750367226 FLOT2 other 5.1027946102801e-43 1 2.65106958504468e-36 14.5683143205919 -2.19967321040812 1.4591025990867e-72 357.823156483088 18.6364704343559 19.2001569043594 2.92456160964544e-62 -224.164116575574 71.776002574141 -3.12310672838075 0.00189100181021259 ERAL1 essential 2.26117129780466e-68 1 4.52371189779956e-58 19.2001569043594 -3.12310672838075 1.398636655147e-34 133.778074305307 20.9469504941451 6.38651790114745 3.668431244487e-10 -269.793251568398 46.7915242276528 -5.76585730047572 1.36932793492058e-08 PRMT7 other 1.98928091461558e-30 0.000186502464736182 4.15449838438153e-06 6.38651790114745 -5.76585730047572 8.46873342663829e-59 173.549233461864 16.9145121806837 10.2603747366747 1.07274703417884e-22 -231.765967911692 37.1784902866456 -6.23387249252941 9.14504761126357e-10 NIP7 essential 1.29918839498058e-54 1.28231857605138e-05 1.51042782412381e-18 10.2603747366747 -6.23387249252941 1.68507478514288e-76 149.111643036417 13.2846170131334 11.2243840292124 1.95347077000623e-26 -248.662379623092 29.1358566563231 -8.53458274991641 1.41232058828762e-16 TERF2 essential 2.61624711141284e-72 2.14319649272646e-12 2.822374568505e-22 11.2243840292124 -8.53458274991641 3.82655053489639e-79 356.086830786936 32.7818226986163 10.8623255656241 5.24979296951161e-25 -677.827751424628 71.9684264303558 -9.41840450104276 1.30058465013538e-19 VPS4A other 5.95105139187087e-75 2.00055930883824e-15 7.52085340812234e-21 10.8623255656241 -9.41840450104276 1.27207012623861e-18 460.819342916089 76.089819530194 6.05625490717883 2.62374692665827e-09 -370.417151725489 165.578292268213 -2.23711180162111 0.0256893389430233 MTSS1L other 1.45741074363158e-14 1 2.87064151245681e-05 6.05625490717883 -2.23711180162111 0.00446019749866369 -12.9053514032433 10.0310364052253 -1.28654217589328 0.198818782737785 -130.526455193622 39.7892493092463 -3.28044528257259 0.00110498084614785 HSPA12B other 1 1 1 -1.28654217589328 -3.28044528257259 7.95547593833974e-15 92.5551540944664 16.0815947576279 5.75534674821756 1.4533988828229e-08 -285.34285551365 63.927975170152 -4.46350529254485 9.82710769212564e-06 ANKEF1 other 8.16152276514274e-11 0.118701633813186 0.000154656175121185 5.75534674821756 -4.46350529254485 1.21956114560121e-11 102.050807075243 19.4455461954676 5.24802985986729 2.20281770722964e-07 -254.457894916711 74.7376183007686 -3.40468295220072 0.000710993423301856 PCED1A other 1.10016610944685e-07 1 0.00220744362441482 5.24802985986729 -3.40468295220072 0.534462108478929 -14.0465518854116 27.8774759498942 -0.503867420087036 0.614560806638862 -120.148630427839 110.122639701397 -1.09104386485493 0.275741963557528 SNAP25 other 1 1 1 -0.503867420087036 -1.09104386485493 0.00162188474307435 115.492484008643 32.0569761798587 3.60272545235276 0.00034398971254187 132.201467722013 127.641155240826 1.03572760268882 0.300792825264079 BTBD3 other 1 1 1 3.60272545235276 1.03572760268882 2.48753463736214e-12 572.689150551959 77.5609489448686 7.3837305801794 5.78391465755133e-13 207.299122262593 319.484297240941 0.648855433750026 0.516704638338335 PCNA essential 2.31365596621053e-08 1 7.06794371152773e-09 7.3837305801794 0.648855433750026 5.98546065765862e-12 59.2166290891206 9.32984380829083 6.34701183705761 4.69225787362587e-10 -78.9492587971678 37.9802363561665 -2.07869319339688 0.0381224098886568 NXT1 other 5.48627323880989e-08 1 5.29052075251316e-06 6.34701183705761 -2.07869319339688 1.07841083691292e-91 94.8095879239043 3.86840856527816 24.508680074512 6.95670202292825e-90 -22.5528644260682 23.7065770366172 -0.951333648515896 0.341858281039675 POLR3F other 1.68199738233308e-87 1 1.08517594855658e-85 24.508680074512 -0.951333648515896 9.55666321478827e-06 193.638203502707 60.9289737606655 3.1780972425916 0.00156667608869336 -726.567015354658 265.967557011652 -2.73178813054567 0.00650377375563566 RIN2 other 0.0582478622941345 1 1 3.1780972425916 -2.73178813054567 2.43935587720518e-35 407.263961266564 42.2151199631588 9.64734819235345 1.94186839838506e-20 -1117.25048937701 167.372045894581 -6.67525143404595 6.08815032221866e-11 PTPRA other 3.49023038910517e-31 8.73466926728711e-07 2.68152607132992e-16 9.64734819235345 -6.67525143404595 6.76030568680928e-31 634.851509486868 51.6015084323269 12.3029641724417 1.1747616215721e-30 1103.2864678942 511.56851657931 2.15667390024608 0.0314959242140919 DAP3 essential 9.3258416949534e-27 1 1.7312462017108e-26 12.3029641724417 2.15667390024608 0.627218395850069 1.85065728854104 2.35154504414526 0.786996316804008 0.43162927977742 -11.6917110157219 21.143766859041 -0.552962539440913 0.580517895561335 RHBG other 1 1 1 0.786996316804008 -0.552962539440913 0.772628758900563 -4.17054775648047 9.17363229263957 -0.45462338400316 0.649563244361405 50.6318648306848 90.0353283041511 0.562355530705056 0.574107605447784 ATP1A4 other 1 1 1 -0.45462338400316 0.562355530705056 0.0201583145007129 370.121722610613 134.839105568095 2.74491380709803 0.00625273743116771 -641.152331487742 1210.55091881171 -0.529636813722055 0.596579839586747 NES other 1 1 1 2.74491380709803 -0.529636813722055 0.598983629636411 9.6988996354242 10.0759166752274 0.962582358314841 0.33618640019514 -27.1844722035242 90.4517414800478 -0.30054116989578 0.763879642199287 BCAN other 1 1 1 0.962582358314841 -0.30054116989578 0.5639555699913 -148.174650371027 140.468689806522 -1.05485891962913 0.291959839839108 -232.297206684426 1314.14710567182 -0.176766516991773 0.859757822575283 CRP other 1 1 1 -1.05485891962913 -0.176766516991773 2.65624150036115e-18 316.705351861602 34.5147627829547 9.17593882516869 9.43754547197575e-19 572.881416182016 309.168765832656 1.85297313148412 0.0644315482496297 ARHGEF11 other 3.02094345836074e-14 1 1.28020304327351e-14 9.17593882516869 1.85297313148412 1.33488048740636e-13 418.449677209348 52.8639864406726 7.91559065790391 1.4184523400216e-14 36.0008792909732 476.781172551129 0.0755081814542762 0.939838509155184 RAB25 other 1.30738194936579e-09 1 1.80015786472142e-10 7.91559065790391 0.0755081814542762 0.0244206959827297 -1.71600657271775 0.677414377432122 -2.53317117245522 0.0115833684576047 6.7961679334862 6.46258629417581 1.05161735938614 0.293442044025982 FCRL2 other 1 1 1 -2.53317117245522 1.05161735938614 1.09057242206932e-15 391.476010828091 45.6667036651714 8.57246044510669 1.07026133682964e-16 23.7649482723673 436.867902632463 0.0543984763567324 0.956637812045226 DCAF8 other 1.151535420463e-11 1 1.40996228513937e-12 8.57246044510669 0.0543984763567324 0.649598645319812 -1.80484764542945 9.96622802043164 -0.181096362809416 0.856361301485776 -85.7487476915977 94.9529204820135 -0.903065932635961 0.366901926797315 SYT11 other 1 1 1 -0.181096362809416 -0.903065932635961 1.03044302814021e-85 132.055618205958 5.52857363443199 23.8860196025093 1.51266065620943e-84 -41.8879555077255 42.6667643267984 -0.981746710083107 0.326702306551753 IGHMBP2 other 1.60501806063119e-81 1 2.35748163270239e-80 23.8860196025093 -0.981746710083107 0.547859588321827 -0.987302304144613 2.11820259718388 -0.466103811532107 0.641341775354374 -9.4866401989563 8.8021929193656 -1.07775872283881 0.281654973074067 ACY3 other 1 1 1 -0.466103811532107 -1.07775872283881 0.0908458348777363 427.290215002448 219.723307686993 1.94467405165384 0.0523690044074802 -471.525177106475 919.138097119058 -0.513007978435908 0.60817007315356 ALDH3B2 other 1 1 1 1.94467405165384 -0.513007978435908 1.5764953409336e-21 241.95275165182 24.981085084802 9.68543803563679 1.95878373728213e-20 -162.113217347941 120.367576444858 -1.34681798982808 0.178653906297191 TESMIN other 1.92363961500718e-17 1 2.70468858443916e-16 9.68543803563679 -1.34681798982808 4.72299239852065e-12 1048.37798597722 177.89995340996 5.89307622560917 6.65164355574722e-09 -755.824461055615 374.722072534393 -2.01702679520231 0.0441834347506458 MMACHC other 4.34656990435855e-08 1 7.17180208180665e-05 5.89307622560917 -2.01702679520231 3.4365811788992e-19 171.58546715811 22.7447540376332 7.5439579110949 1.93683234686008e-13 -154.914230534165 49.5790130546688 -3.12459286681135 0.0018757861884002 DPH2 other 3.99330732988087e-15 1 2.39663634600467e-09 7.5439579110949 -3.12459286681135 3.306587510542e-13 32.9715324380833 9.17470604897552 3.59374265094466 0.000355504220466885 -106.453897602647 19.7666986403859 -5.38551730561358 1.07579207344332e-07 TOE1 essential 3.18490509015405e-09 0.00142219712109206 1 3.59374265094466 -5.38551730561358 2.97632338230329e-17 889.829818797718 111.429290268873 7.98560070382398 8.37183663642251e-15 -232.109867715122 230.517533789608 -1.00690764775823 0.314426810597822 NASP essential 3.29359945485683e-13 1 1.06699057931205e-10 7.98560070382398 -1.00690764775823 2.80549438472603e-22 89.7772844397341 10.4646425431064 8.57910665079288 9.97132434663338e-17 -64.6279985390539 22.545837918376 -2.8665157078229 0.00431059276137307 MUTYH ts 3.47348259772929e-18 1 1.31461940186014e-12 8.57910665079288 -2.8665157078229 9.75011901937926e-70 331.939031097711 16.1406634118685 20.5653895770872 1.36158085012886e-69 -77.1884387213858 110.853240688626 -0.696311972856068 0.486537576981796 CTNNBL1 essential 1.50834341229797e-65 1 2.11222037280489e-65 20.5653895770872 -0.696311972856068 7.15036777245469e-09 66.5807942045284 11.5000584346275 5.78960486009784 1.21656717034634e-08 -94.5008306678646 69.2271253167038 -1.36508384878814 0.172812494152172 LPIN3 other 5.58658234061885e-05 1 0.000129832048419361 5.78960486009784 -1.36508384878814 4.32910993933723e-24 22.8889241971188 2.18893236141154 10.4566612475677 2.03098819409608e-23 -25.1587478890647 14.0679599978258 -1.78837215153817 0.0742796204565251 ZSWIM3 other 5.5174506176853e-20 1 2.87892576513119e-19 10.4566612475677 -1.78837215153817 3.53438952371485e-17 163.443041129677 19.095374461766 8.55930013087376 1.20265319901911e-16 690.965326519725 185.902980735955 3.71680606617669 0.000222964027771238 RBM38 other 3.9030263510383e-13 1 1.58281187522906e-12 8.55930013087376 3.71680606617669 0.764318393440072 -3.88007151361568 10.3031476271864 -0.376590887951321 0.706626968755643 40.9873511492776 71.4780607784381 0.573425617635695 0.566597501804985 VSTM2L other 1 1 1 -0.376590887951321 0.573425617635695 1.0123240973406e-30 186.53417547361 15.9663066279026 11.6829884218573 3.06818290136703e-28 -291.274765354403 97.2017068874351 -2.99660134252288 0.00285696920977614 OSER1 other 1.39386904962827e-26 1 4.47525157993396e-24 11.6829884218573 -2.99660134252288 1.72454140663567e-30 921.979950335983 80.8281784013656 11.4066649598082 3.92647994235385e-27 -1782.57361522432 502.217460749993 -3.54940589393743 0.000420029469715196 SERINC3 other 2.36969234685807e-26 1 5.69182532443613e-23 11.4066649598082 -3.54940589393743 2.5940485642834e-14 192.809690233891 24.3555584475013 7.91645531961398 1.50108829352457e-14 -107.314421490486 161.672366590473 -0.663777142338244 0.507128844958652 PPP1R3D other 2.6077970216741e-10 1 1.90337995618916e-10 7.91645531961398 -0.663777142338244 0.0021712657286317 15.3821053892287 4.50934808154733 3.41115946497315 0.000695022939542594 6.17386109401906 9.95176026489641 0.620378800300946 0.53526870170942 DMGDH other 1 1 1 3.41115946497315 0.620378800300946 0.00128584022891321 58.548828578226 15.997795480944 3.65980604314933 0.0002770052568685 44.3922190304718 35.3008661904851 1.25753908674448 0.209098064646344 BHMT2 other 1 1 1 3.65980604314933 1.25753908674448 1.18034794385725e-24 175.721843837493 39.3401067293541 4.46673531026228 9.66452038548969e-06 -632.746766594391 86.8593867174099 -7.28472523819426 1.1384602398965e-12 AP3B1 other 1.51804549059481e-20 1.671942708312e-08 0.087193302917888 4.46673531026228 -7.28472523819426 0.0829275993493378 2.14143483864495 20.4121987490696 0.104909562412651 0.916486454187583 -89.5731140736835 45.0252851484436 -1.98939582011242 0.0471606138137002 ZBED3 other 1 1 1 0.104909562412651 -1.98939582011242 4.86511647279782e-07 -117.857680352079 118.085739138218 -0.998068701709422 0.318691417773493 -1549.28954508641 286.593670552487 -5.40587495215695 9.68105189251753e-08 PATJ other 0.00333455083045563 0.00128186808108825 1 -0.998068701709422 -5.40587495215695 0.173271433230802 77.4716968100547 52.4839062624126 1.47610386358642 0.140495659847017 -70.4959545639301 116.977598894142 -0.602644910054317 0.54699652792187 KANK4 other 1 1 1 1.47610386358642 -0.602644910054317 0.52061407408535 14.6693708462203 13.7695793815217 1.06534632901758 0.28719622455897 1.81125715025681 29.5653250556521 0.0612628863997741 0.951172556697912 SYT4 other 1 1 1 1.06534632901758 0.0612628863997741 0.109276094651822 0.463152988449434 4.69292552106846 0.0986917406573258 0.921419515272623 -18.7684915411078 10.0269997017103 -1.87179536246584 0.0617732710253461 SLC14A2 other 1 1 1 0.0986917406573258 -1.87179536246584 9.66089669528097e-09 89.2684944328291 27.0025629180931 3.30592672642251 0.00100916479817618 -119.780822679998 43.0489871591893 -2.7824306815179 0.00558305448339446 FBXO44 other 7.47656795247794e-05 1 1 3.30592672642251 -2.7824306815179 1.88900655988914e-14 8.17562247018313 4.25563339706682 1.92112940833159 0.0552366934968277 -37.4460088730428 6.57473606455072 -5.69543910286256 2.01442957177835e-08 RSG1 other 1.90972899802223e-10 0.000272532176765893 1 1.92112940833159 -5.69543910286256 2.52686678286496e-21 37.4523516592115 11.0897955039856 3.37719046719585 0.000784572459113319 -115.095142944399 17.9663078496881 -6.40616557989109 3.22860706428011e-10 CASP9 other 3.07191194792893e-17 4.57073902090135e-06 1 3.37719046719585 -6.40616557989109 5.01980643647271e-27 191.473715481569 59.7390190633398 3.20517006277848 0.00142871026197845 -1332.37028332734 141.181269510558 -9.43730204400594 1.09556725385127e-19 DCTN4 essential 6.66329106377388e-23 1.68553022005018e-15 1 3.20517006277848 -9.43730204400594 0.321861688042151 50.8158625863939 54.5982497531509 0.93072328904575 0.352410315941043 -71.2263004802424 117.682916938209 -0.605239080856918 0.54527301000543 ATP8A2 other 1 1 1 0.93072328904575 -0.605239080856918 6.56079820855483e-05 13.3195661997288 3.09307963496622 4.30624742058227 1.97943473491342e-05 7.29991200323455 6.72836718831607 1.08494554457595 0.278439961506987 MTUS2 other 0.365436460216504 1 0.174040288706121 4.30624742058227 1.08494554457595 1.96799850175038e-31 50.1536919679653 8.21188708621491 6.10745026586605 1.98886503419143e-09 -111.512080988906 16.4252203727736 -6.78907670388081 3.10000348115599e-11 ZMYM5 other 2.72981072177795e-27 4.46865501808636e-07 2.18576267257638e-05 6.10745026586605 -6.78907670388081 3.74560559637421e-28 83.0913000751495 12.3546473228832 6.72550967288625 4.56606281460488e-11 -151.32636602793 26.6950805373135 -5.66869861345466 2.37233155023807e-08 USPL1 essential 5.03484304264621e-24 0.000320430822490656 5.30759141569671e-07 6.72550967288625 -5.66869861345466 1.26753986834416e-11 146.176856923417 30.291790348487 4.82562619250129 1.83222918713199e-06 -146.749821852673 61.1398473306822 -2.40023206238902 0.0167318572630993 XPO4 other 1.14256043732542e-07 1 0.0173457137145786 4.82562619250129 -2.40023206238902 1.15828181951474e-47 683.979096738097 48.4598841151617 14.1143362025519 1.30584818333855e-38 -88.218183060727 104.356683190487 -0.845352500325236 0.39829696337305 POMP other 1.74147671564041e-43 1 1.96856613638286e-34 14.1143362025519 -0.845352500325236 3.60079825658144e-20 112.173927687759 11.5770274024212 9.68935494307456 1.44677389595836e-20 70.0595375694759 24.865223872555 2.817571155947 0.00501741086440447 CDK8 other 4.27666808934178e-16 1 2.00002023377283e-16 9.68935494307456 2.817571155947 0.075867548883261 -39.1827184348773 20.6487671933014 -1.8975814908499 0.0582975038632361 -84.7536011820092 42.1103822735112 -2.01265333170157 0.0446592666110727 ALOX5AP other 1 1 1 -1.8975814908499 -2.01265333170157 6.78948360679329e-05 71.2190103381703 17.010515397477 4.1867638148538 3.30932533337273e-05 116.988160369662 36.6144544128787 3.19513597145157 0.00148021318744047 WASF3 other 0.377563183373775 1 0.286024988563405 4.1867638148538 3.19513597145157 2.72631712332021e-06 396.505838889359 78.2043768954479 5.07012336943048 5.49419992683723e-07 283.356542683089 168.41938362123 1.68244614479976 0.093068031697566 GPR12 other 0.0174893243460992 1 0.00537332752844681 5.07012336943048 1.68244614479976 5.09931155344328e-05 36.4590549374671 14.3402347588787 2.54243082840004 0.0112855242400043 336.874486685897 87.0831157438411 3.86842482389845 0.000122860439550943 CHRM3 other 0.287856137191873 1 1 2.54243082840004 3.86842482389845 6.9307585118201e-15 490.648957020856 95.4774157234706 5.13890068455469 3.86102274946368e-07 -622.859055511198 170.701066236864 -3.64882932041516 0.000288862066620213 MYH10 other 7.12759205355579e-11 1 0.00381507657874506 5.13890068455469 -3.64882932041516 9.95514591379319e-14 98.9115871888716 22.822934132433 4.33386814398729 1.75288935968186e-05 -149.800063271928 40.0875633468589 -3.73682136716015 0.000206560826525999 PEMT other 9.79287703539836e-10 1 0.154727543779117 4.33386814398729 -3.73682136716015 1.60948327807647e-67 179.975464377698 17.4519382831167 10.3126347032644 7.02669102050541e-23 -343.543558196102 31.3726360307973 -10.9504205467101 2.46391237349902e-25 SCO1 other 2.48745640626718e-63 3.83778991296208e-21 9.91395836083109e-19 10.3126347032644 -10.9504205467101 1.37425008667197e-11 184.656732273686 76.4388135975647 2.41574566091341 0.0160363925424468 -653.740286830051 134.418695247559 -4.86346252376619 1.51825654350093e-06 MPRIP other 1.23668765299611e-07 0.0191163681392202 1 2.41574566091341 -4.86346252376619 0.467731182968277 156.482172194315 250.806135521671 0.623916842659514 0.532944696061558 2121.52280708534 2020.57391565565 1.04996050411595 0.294204200163047 CHI3L1 other 1 1 1 0.623916842659514 1.04996050411595 8.76261415691904e-05 72.1816273530981 16.951070680564 4.25823410882602 2.43179221720977e-05 -164.226365572233 137.994775157889 -1.19009118558533 0.234535440774651 PIK3C2B other 0.479402620525041 1 0.212441368095446 4.25823410882602 -1.19009118558533 1.2515802974242e-23 146.076118471933 13.6189257004936 10.725964858347 1.78185335333214e-24 90.6672178353993 124.96598576558 0.725535170870249 0.46843634456201 DSTYK other 1.58400002442007e-19 1 2.5434174765463e-20 10.725964858347 0.725535170870249 0.841416361555995 -25.2997136272741 44.7181162925352 -0.565759824536646 0.571791201522829 -52.7867262667466 360.263353007748 -0.146522608602966 0.883563324647866 CHIT1 other 1 1 1 -0.565759824536646 -0.146522608602966 4.18173552713909e-08 81.0203077259864 15.5698830246723 5.20365551864456 2.78022869838946e-07 374.676649727144 142.375990216622 2.63159995696663 0.00874134202476003 SLC41A1 other 0.000310912036442791 1 0.00276938580646574 5.20365551864456 2.63159995696663 0.535351831399312 -12.6339401585576 22.6174246433968 -0.558593224372522 0.57666836747256 171.212754385883 176.250353376208 0.971417935375302 0.331770336599858 LGR6 other 1 1 1 -0.558593224372522 0.971417935375302 0.00162706292024617 -3.85068282957244 6.70539785290463 -0.574266123210631 0.566025102488383 220.266199539507 61.5359835204515 3.57946987986796 0.000375076653361572 TMCC2 other 1 1 1 -0.574266123210631 3.57946987986796 0.118158146708993 -9.30991024315277 159.220131820718 -0.0584719415609813 0.953394626456036 -564.595466360686 313.288311387412 -1.80215937153974 0.0720851911659788 DCLK1 other 1 1 1 -0.0584719415609813 -1.80215937153974 0.0174209617510163 14.8648906753858 8.14930865494214 1.82406769761641 0.0686984741108581 45.1391383617237 15.9928834321121 2.82245153310434 0.00494279602445167 CCNA1 other 1 1 1 1.82406769761641 2.82245153310434 1.48169298816472e-32 121.688137767654 19.2204429650354 6.33118279266619 5.11489934791243e-10 -234.741689266657 36.8826739987589 -6.36455180214309 4.18020224671072e-10 COG6 other 2.07600004571759e-28 5.90578973415291e-06 5.75733070601023e-06 6.33118279266619 -6.36455180214309 0.00910008327276217 40.7165431637047 28.8458306183172 1.41152264611335 0.158661197599617 169.647894073551 55.224931571828 3.07194394352303 0.00223289553757964 EPSTI1 other 1 1 1 1.41152264611335 3.07194394352303 0.011555398108384 -3463.43301734359 1789.27927808249 -1.93565815005427 0.0534341463004181 -10157.7876466959 3429.78897334768 -2.96163633553852 0.00319550187376139 POSTN other 1 1 1 -1.93565815005427 -2.96163633553852 5.15345335577379e-09 18.0164495509029 3.37640504298756 5.33598585522822 1.40360758472459e-07 -0.879847584726025 6.62195953372689 -0.132868160888751 0.894347420181159 RFXAP other 4.0563212597332e-05 1 0.00142017015422434 5.33598585522822 -0.132868160888751 1.91282888189101e-34 3418.65391519666 1413.13673283494 2.41919542232716 0.0158830824763122 -27319.6125959639 2701.24811234149 -10.1136998379178 3.83309011800005e-22 TPT1 essential 2.71870368983169e-30 5.93975644685288e-18 1 2.41919542232716 -10.1136998379178 5.02887182140133e-36 83.8808627141897 13.4660956514438 6.22904105877165 9.41211931135893e-10 -189.287659071676 25.7494148742821 -7.35114409379188 7.27235143809316e-13 GPALPP1 other 7.22447725862515e-32 1.06990834357227e-08 1.04898069725095e-05 6.22904105877165 -7.35114409379188 0.0616752091962083 0.00548238921059894 4.63183216198018 0.00118363295967424 0.999056038962856 -18.9003005953593 9.20687577604626 -2.05284627001622 0.0405732944491639 KL other 1 1 1 0.00118363295967424 -2.05284627001622 5.1859364872552e-15 154.090253209162 18.616142659416 8.27723852509391 1.01509180314929e-15 117.030839596506 37.1530286747252 3.14996768153443 0.00172431828021526 RFC3 essential 5.35396082944227e-11 1 1.31383332081612e-11 8.27723852509391 3.14996768153443 3.17256480399881e-16 -75.0870691609977 34.3549411752159 -2.18562648027954 0.0292757706666838 -575.894555555553 68.4234282996558 -8.41662819105557 3.56164900448058e-16 STARD13 other 3.40670008653392e-12 5.3909119331818e-12 1 -2.18562648027954 -8.41662819105557 5.79079529104672e-64 269.148635594869 15.0212999710584 17.917799132794 2.0360735486692e-56 -227.603634036158 49.7927148379151 -4.57102278469957 6.05318043339255e-06 FAM104A other 8.93172265691046e-60 0.0740425030612577 3.13840376791871e-52 17.917799132794 -4.57102278469957 5.03005329376841e-16 399.421721522183 77.052999895504 5.18372707180592 3.11052848408602e-07 -1581.38851047676 266.973444520274 -5.92339254309866 5.71421798876742e-09 SLC39A11 other 5.36404883247463e-12 7.86333537434284e-05 0.00308987187262622 5.18372707180592 -5.92339254309866 0.00117680203511587 95.7215578700193 27.2966972478997 3.50670841240269 0.000491020314919701 122.102046159659 42.901881525146 2.84607671782627 0.00459249680527046 EPHB2 other 1 1 1 3.50670841240269 2.84607671782627 1.56840092328986e-16 170.065398888959 52.9181020832409 3.21374713366409 0.00138748924034499 -490.487839361713 89.2196238336097 -5.49753314670379 5.92054731108577e-08 SRRM1 essential 1.69779399946127e-12 0.000789445778460176 1 3.21374713366409 -5.49753314670379 2.62514159919124e-16 160.273475660264 72.9996757807668 2.19553681500721 0.0285636456525539 -851.927953307302 132.569956828002 -6.42625202339473 2.94673443537115e-10 BTBD2 other 2.82675247400912e-12 4.17493334803385e-06 1 2.19553681500721 -6.42625202339473 0.0124449210246984 -3.44843544216696 2.2021262820584 -1.56595717069577 0.117957746340794 -19.588128840614 6.78303963234322 -2.88780987615241 0.00403843631370883 PRAM1 other 1 1 1 -1.56595717069577 -2.88780987615241 5.34372915951569e-09 61.0605331764963 10.3901771751968 5.87675572292057 7.36404689254834e-09 -50.8555890824287 39.908455423074 -1.27430612243202 0.203108180984564 KMT5C other 4.20230861104313e-05 1 7.92592367044978e-05 5.87675572292057 -1.27430612243202 3.52052200343008e-17 33.5794565366289 7.23160697750749 4.64342941217233 4.33005999110117e-06 -132.224459914553 22.2749608565192 -5.93601312102215 5.29407465030767e-09 ZNF414 other 3.88806450058818e-13 7.29205842333379e-05 0.0400010941977926 4.64342941217233 -5.93601312102215 7.3008716460097e-11 -1.9681113175535 12.9143792855841 -0.152396896051399 0.878934772251381 -181.265805086257 28.5217567374213 -6.35535204773806 4.65141147801852e-10 PDE6B other 6.34445746038243e-07 6.56407187777974e-06 1 -0.152396896051399 -6.35535204773806 1.0674955197549e-11 208.27324377333 29.6292392430961 7.0293145924042 6.30470801668643e-12 -84.4063411624734 113.341653246273 -0.744707164091491 0.456773334532539 HSPBP1 other 9.6608344537818e-08 1 7.51804818197239e-08 7.0293145924042 -0.744707164091491 7.99654725306024e-09 140.966668587232 50.0754391687608 2.81508601676274 0.00506065047263815 -323.345449441853 90.9976993787452 -3.55333653102639 0.000414871357500544 CSNK1G2 other 6.22211341760618e-05 1 1 2.81508601676274 -3.55333653102639 3.1871033306144e-13 32.5369358445642 8.40229279543473 3.87238776804382 0.000120907238439157 -92.1551864393029 19.4911745880468 -4.72804684104662 2.89271384802253e-06 SLF1 other 3.07364385874443e-09 0.0359651112724641 0.990713911770454 3.87238776804382 -4.72804684104662 4.64787687475978e-16 697.870487208785 156.430436117573 4.46121934151142 9.92873985223264e-06 -1539.55848476653 316.342242501888 -4.86674960824223 1.49279763115166e-06 CNDP2 other 4.96300292686849e-12 0.0188077573548797 0.0895075897678773 4.46121934151142 -4.86674960824223 5.61451258672366e-05 121.333951801522 31.5509221325196 3.84565469408144 0.000134849807692409 -36.7816529626423 74.6290492961094 -0.492859728343877 0.62231582814098 MACROD1 other 0.315367171996268 1 1 3.84565469408144 -0.492859728343877 0.738897059620161 -274.867695318788 669.120504170154 -0.410789526857618 0.681395123735809 -1334.29486718218 1732.82591145167 -0.770010915905783 0.44164107253995 WDR74 essential 1 1 1 -0.410789526857618 -0.770010915905783 0.413842903474209 24.4608755869335 28.3100006705022 0.864036559787889 0.387960148412297 -42.08587202976 71.7381871000289 -0.586659263790388 0.557683305118148 LGALS12 other 1 1 1 0.864036559787889 -0.586659263790388 5.58562130235917e-16 997.275042147736 196.908967208534 5.06465021012266 5.65024810795911e-07 -2091.19051812527 479.951832796539 -4.35708413892393 1.58218197538617e-05 RTN3 other 5.9531551840544e-12 0.188785953303078 0.00551633722780048 5.06465021012266 -4.35708413892393 4.0699465129026e-05 151.852512346571 229.213410468238 0.662494013925129 0.507943193425529 -2223.23081836309 576.383025110505 -3.85721078086374 0.000128827296873409 RARRES3 other 0.233045137328803 1 1 0.662494013925129 -3.85721078086374 0.0343386798615851 0.100892959271561 13.2387086713979 0.00762105744418562 0.993922207880598 -80.3345564816443 33.6208427255153 -2.38942721149216 0.0172239202134358 HRASLS2 other 1 1 1 0.00762105744418562 -2.38942721149216 0.191646612532872 -208.670839165733 422.584716550963 -0.493796464928631 0.621649236198695 3332.51289096525 2151.57223115245 1.54887335071259 0.121993702442885 MYH11 other 1 1 1 -0.493796464928631 1.54887335071259 1.03366789123489e-36 236.997506648936 18.5640259113637 12.7664929892099 7.82639240229566e-33 -172.032515144801 94.5179536431903 -1.82010410206543 0.0692925297958559 FOPNL other 1.48910196411298e-32 1 1.16190621604481e-28 12.7664929892099 -1.82010410206543 6.32392451475212e-17 99.1387632996269 11.1026102245642 8.92932033948964 6.7091984010604e-18 86.6113058667684 50.9957903084413 1.69840109042161 0.0900081376706684 MED10 other 6.92849169836242e-13 1 9.01112437246423e-14 8.92932033948964 1.69840109042161 0.057652402507514 82.9012760139174 45.1891734113704 1.83453844705772 0.0671292314372255 -224.801184733663 208.380433135388 -1.0788017922374 0.281162230467531 PDZD2 other 1 1 1 1.83453844705772 -1.0788017922374 3.3145070900032e-25 332.118631945901 36.7351519396284 9.04089446783055 2.76211127855547e-18 -132.195421713733 79.676818543235 -1.65914533399699 0.0976660699883036 MORC2 other 4.29328103368115e-21 1 3.72553569251562e-14 9.04089446783055 -1.65914533399699 2.97127808146002e-05 55.8105702831469 55.7044857530633 1.00190441628981 0.316836019694941 -350.025843250846 101.934063696086 -3.4338456700249 0.000640516140789377 LARGE1 other 0.17245297984794 1 1 1.00190441628981 -3.4338456700249 0.220942492825404 18.5219422422709 38.7744127811815 0.477684661449217 0.633065484525507 -109.972622172397 88.3144881732367 -1.24523874221719 0.213577175248987 GSTT2B other 1 1 1 0.477684661449217 -1.24523874221719 0.318675902166885 15.2175605716722 24.3149054041451 0.62585316778892 0.531673256649176 -48.7289230423575 52.8770257328548 -0.921551890769076 0.357170117289838 MYO18B other 1 1 1 0.62585316778892 -0.921551890769076 2.13259659311345e-22 43.8310008006409 8.25882184871631 5.30717354164186 1.62052226359841e-07 -101.629721121434 18.8011548251929 -5.40550418664995 9.66533648931657e-08 SLC2A11 other 2.64633911239448e-18 0.0012798838579153 0.00163462080729172 5.30717354164186 -5.40550418664995 0.115383805179254 -86.7938735931537 51.6658169869614 -1.67990905118286 0.0935480892866903 -197.516725372448 105.633970964207 -1.86982202382012 0.0620444534672088 C1QTNF6 other 1 1 1 -1.67990905118286 -1.86982202382012 3.31500372273582e-19 200.01135316943 38.394397813541 5.20938898796558 2.69455865193251e-07 -303.415385165455 70.1024647517055 -4.32817000429466 1.79033557928144e-05 FAM83F other 3.85435482842494e-15 0.212835093664977 0.00268566660838114 5.20938898796558 -4.32817000429466 0.262308613986356 -29.5133306880325 19.4840014056709 -1.51474689790581 0.130417300466591 5.05554589235382 60.616594160901 0.0834020116493903 0.933562569151296 GIMAP6 other 1 1 1 -1.51474689790581 0.0834020116493903 0.151407357099243 -29.4051001442931 22.2747827468971 -1.32010715787517 0.187354430829396 62.9307592733151 69.1934537178426 0.909490073005092 0.363494262712747 GIMAP4 other 1 1 1 -1.32010715787517 0.909490073005092 1.20532532109239e-15 112.162982591927 23.2190057770497 4.83065397670008 1.77195343536046e-06 -394.290410987032 76.2206049542596 -5.17301602661967 3.243808815895e-07 ADCK2 other 1.27101555109193e-11 0.00420202994011038 0.0167963466137818 4.83065397670008 -5.17301602661967 2.6500328673334e-40 468.383870798734 52.5653632756912 8.9105038301017 7.63865961147962e-18 -1421.21736784309 171.517168375009 -8.2861522336686 9.16720296482539e-16 MKRN1 other 3.88653820323116e-36 1.38433931971828e-11 1.02510811986056e-13 8.9105038301017 -8.2861522336686 1.1793821299049e-14 178.158542192005 39.8150385404806 4.4746545205744 9.32544912666292e-06 -617.350405709587 122.335846252808 -5.04635742195979 6.14929401524215e-07 AGAP3 other 1.20143657573412e-10 0.00788216506873738 0.0842740837576528 4.4746545205744 -5.04635742195979 3.33730600596582e-12 43.0241829071198 8.75092693042982 4.91652864309845 1.17113517553292e-06 -100.859990193828 27.2397592829647 -3.70267553197155 0.000235303304825008 KRBA1 other 3.09134655332614e-08 1 0.0112265017926585 4.91652864309845 -3.70267553197155 4.2589817470372e-11 33.4213473704959 8.16211767710552 4.09469070315437 4.87723993730793e-05 -105.72370173725 25.5050261367342 -4.14521048402217 3.94345733183727e-05 ZNF767P other 3.74577444651922e-07 0.45775652707967 0.414467849872428 4.09469070315437 -4.14521048402217 6.09331115699198e-06 96.2277344632785 21.5192749056918 4.47169966855279 9.45732521794353e-06 -24.2051410933402 60.3136470803584 -0.401321131535799 0.688341882966006 ACTR3B other 0.0377054094394664 1 0.0853712747423763 4.47169966855279 -0.401321131535799 0.35975436635232 -205.981217783474 178.628814314051 -1.15312425139504 0.249379169708114 -498.648341778488 439.559762591666 -1.13442672468115 0.257128410496522 NTS other 1 1 1 -1.15312425139504 -1.13442672468115 0.00169008453094615 -27.0856299024082 147.905020458038 -0.183128536262855 0.854766803900446 -1424.32272584816 405.387381956946 -3.51348559240412 0.000479852284364095 BTG1 other 1 1 1 -0.183128536262855 -3.51348559240412 0.000352878869973246 10.3018572289297 4.1621689725026 2.47511749210305 0.0136308674928342 -24.2543533479481 10.3152410289821 -2.35131232317328 0.019072554946533 LRRIQ1 other 1 1 1 2.47511749210305 -2.35131232317328 8.0420259622652e-17 56.4179069078815 11.4978327177595 4.90682968632331 1.2336605373696e-06 -167.418374064609 28.8094554874531 -5.81123007123553 1.07127450671572e-08 C12orf29 other 8.78752176896718e-13 0.000146293246637098 0.0118135333058513 4.90682968632331 -5.81123007123553 1.86883994874799e-14 518.108892165085 63.3350854664189 8.18044040439155 1.99645720696968e-15 -0.12543570497902 295.203018953873 -0.000424913354285919 0.999661123403875 ATP13A3 other 1.88977095617397e-10 1 2.57243511118043e-11 8.18044040439155 -0.000424913354285919 0.578796377204513 -0.244626930990741 2.57896211151763 -0.094854798330785 0.924465282107864 -10.1672585206603 9.76204549049005 -1.04150902908259 0.298104568934002 SFTPD other 1 1 1 -0.094854798330785 -1.04150902908259 2.06848828687239e-09 12.2336072061719 1.97152379278877 6.2051532174852 1.08487781904e-09 -3.99559735075725 7.24533103049027 -0.551472021629201 0.581536998169972 DYDC2 other 1.66761525687652e-05 1 1.20595018364487e-05 6.2051532174852 -0.551472021629201 1.12371342674586e-47 566.257509722632 37.7924525128 14.9833491100067 9.96830417777863e-43 -501.268233253729 142.414801363812 -3.51977623430582 0.000468170509495289 TMEM254 other 1.68961550845508e-43 1 1.51368698939569e-38 14.9833491100067 -3.51977623430582 0.133768474686124 43.0731208125375 46.5987668125401 0.924340358314937 0.355725074496199 -360.06193734139 227.103134753373 -1.58545560250591 0.113452618448011 TMTC1 other 1 1 1 0.924340358314937 -1.58545560250591 1.1241305074287e-33 433.231564763765 34.4217413076679 12.5859863070686 5.66422471937773e-32 -190.79944618884 141.070618179315 -1.35251017292853 0.176787833598522 KRAS essential 1.58817158089526e-29 1 8.38305258467904e-28 12.5859863070686 -1.35251017292853 1.91433072339015e-39 356.117339787847 25.7463774144092 13.8317454939716 1.94906938274208e-37 -240.85883125682 119.447427074544 -2.01644218846594 0.0442510874788428 IPO8 other 2.79645432072834e-35 1 2.92886656144653e-33 13.8317454939716 -2.01644218846594 1.18801851039382e-08 379.276914082899 74.6820808623154 5.07855311078086 5.22433866130494e-07 -256.846509122946 174.881287848389 -1.46869063170221 0.142491545640472 LARS essential 9.1441784745012e-05 1 0.00511723971874818 5.07855311078086 -1.46869063170221 0.633849150533922 -2.78400266012483 11.9681325875727 -0.23261796606562 0.816144926262998 22.3434593274048 28.3011464054003 0.789489549552003 0.430167388702722 SPINK5 other 1 1 1 -0.23261796606562 0.789489549552003 7.15956519131012e-26 60.3083048018041 5.36771513822753 11.2353772971862 2.31362958182395e-26 -37.3480488257912 55.6812903375658 -0.670746827154508 0.502680776061974 IMPA1 other 9.36972296586755e-22 1 3.34088111615379e-22 11.2353772971862 -0.670746827154508 1.51339603952733e-10 107.349353755487 15.6155666329983 6.87450902541314 1.8125770905099e-11 63.0160055736474 170.5374626108 0.369514150198553 0.711897007309659 LRRCC1 other 1.29516433062749e-06 1 2.13394700865731e-07 6.87450902541314 0.369514150198553 1.14543891431634e-48 188.708622398165 11.4555070234998 16.4731794071663 3.118252398074e-49 292.937389979448 122.845803094039 2.38459420347639 0.0174610401424108 E2F5 other 1.72606189998329e-44 1 4.77497989717072e-45 16.4731794071663 2.38459420347639 7.04511470133411e-13 91.1431471939065 12.1625742771985 7.49373817718631 2.79711908631155e-13 12.2748061436593 31.7044360151552 0.387163680747757 0.698789286819142 CCDC59 essential 6.6928589662674e-09 1 3.44856812151351e-09 7.49373817718631 0.387163680747757 0.000579037861863383 38.4141737654128 62.0558053005051 0.619026271263296 0.536159622850135 -425.388410696674 130.816875516815 -3.25178543682613 0.0012182630988388 SWAP70 other 1 1 1 0.619026271263296 -3.25178543682613 9.35510773152452e-05 9.9657981763144 10.7561725381181 0.926518995581116 0.354593313069734 -87.0645467846783 24.5440926858389 -3.54727094209971 0.000423368842964386 ARNTL other 0.510165129314511 1 1 0.926518995581116 -3.54727094209971 0.196342749162025 72.8534855018161 44.5834354868408 1.63409312688161 0.102822120229161 128.865975359151 94.3581564808773 1.36571103299657 0.172598241921167 LYVE1 other 1 1 1 1.63409312688161 1.36571103299657 0.00616308157737959 33.7285903960522 14.1684144646623 2.38054797734604 0.0176328228210641 -30.0650757976682 29.9865960203342 -1.00261716192397 0.316494668825111 AMPD3 other 1 1 1 2.38054797734604 -1.00261716192397 3.49451937167123e-05 25.4890383351514 9.26843994770237 2.75008938710016 0.00615840824006974 -45.4931244820883 19.954670584902 -2.27982337711498 0.0230087140770031 MICALCL other 0.201354206195696 1 1 2.75008938710016 -2.27982337711498 7.75791912426985e-08 139.28311145376 45.4414283209146 3.06511297290482 0.00228444193835869 -312.964722947296 96.0924616774656 -3.25691232677296 0.00119689092526559 SBF2 other 0.00056547472496803 1 1 3.06511297290482 -3.25691232677296 0.138300035857157 71.6478813970496 127.530300103461 0.561810654714402 0.574478996936156 -423.375251495603 275.377806451811 -1.53743417797792 0.124774913222103 MICAL2 other 1 1 1 0.561810654714402 -1.53743417797792 0.00294339160855886 48.5396541890501 17.4358673047488 2.7838967423106 0.00556106419846902 -28.2676625396379 39.8538140284951 -0.709283746831027 0.478457392619918 RRAS2 other 1 1 1 2.7838967423106 -0.709283746831027 5.21111509935458e-27 349.879728790513 105.86376523647 3.30499985532329 0.00101255921890583 -2195.82624642924 240.116861802764 -9.14482319127144 1.19910094766286e-18 HSD17B4 other 6.91462862533359e-23 1.83822175276716e-14 1 3.30499985532329 -9.14482319127144 1.56218559098865e-17 179.523739428224 20.8782818995473 8.59858777134898 9.1319830676984e-17 -134.272157964502 82.3278299234463 -1.63094494400443 0.103495992314258 ZFC3H1 essential 1.74136827827505e-13 1 1.20487384595213e-12 8.59858777134898 -1.63094494400443 3.63507407373516e-55 1284.6132585642 199.761617158356 6.43073117267495 2.82193865855034e-10 -3816.53948888065 410.350648267869 -9.30067859034865 3.56390480235657e-19 SARAF other 5.54421497726086e-51 5.47095026209758e-15 3.20656889771075e-06 6.43073117267495 -9.30067859034865 0.000270519346409078 13.0790581931784 7.7030144878075 1.69791426640574 0.0901315645286531 -39.3139341197245 17.77486731446 -2.21177089112459 0.0274233279237769 RNF122 other 1 1 1 1.69791426640574 -2.21177089112459 0.167389384844523 20.5118546052651 13.1925975515597 1.55480029805352 0.120613944803809 -2.19399192614091 30.4751215746021 -0.0719928851069582 0.942635793598032 DUSP26 other 1 1 1 1.55480029805352 -0.0719928851069582 2.34411258580929e-22 134.735883135815 26.5738239562683 5.0702482020482 5.53738852981673e-07 -454.614986251066 66.3827316530529 -6.84839226904816 2.11851423353325e-11 DPF2 other 2.90693401766211e-18 3.06188862172561e-07 0.00541335102674883 5.0702482020482 -6.84839226904816 1.97554372383256e-20 146.620277350206 29.0758903393777 5.04267541385093 6.31349386247153e-07 -398.850433163967 68.1444811971684 -5.85301151548778 8.46628573299929e-09 MEN1 ts 2.35879920625608e-16 0.000116021979685022 0.00614871167266102 5.04267541385093 -5.85301151548778 9.69355202508124e-05 2.03800351970442 6.29689362657803 0.323652207034653 0.746325061320618 -49.8842490910526 13.0305062333126 -3.82826639256141 0.000143964671345787 GSC other 0.52742616568467 1 1 0.323652207034653 -3.82826639256141 0.722724158741581 1.32616506640796 7.16798192229172 0.185012334124856 0.85328793789523 -9.3043009155487 14.5460001558887 -0.63964669433762 0.522670113249791 UNC79 other 1 1 1 0.185012334124856 -0.63964669433762 4.02197015853158e-13 25.7385815094824 10.5795589896982 2.4328595865428 0.0153001620314121 -125.005560736373 21.5481915854071 -5.80120889685375 1.11604103655531e-08 CATSPERB other 3.85787377606349e-09 0.000152250318206876 1 2.4328595865428 -5.80120889685375 2.94256574235783e-37 210.065305075399 27.0296192301081 7.77167089506791 3.91272451433927e-14 -365.17755288183 52.7426643917414 -6.9237600544695 1.24850475626432e-11 COX16 other 4.25347878057825e-33 1.81120584991265e-07 4.92103362168449e-10 7.77167089506791 -6.9237600544695 8.8579621098923e-14 171.916881717551 41.4621288587471 4.14635925480905 3.92009388783497e-05 -347.465597131822 81.0103194720599 -4.28915228820523 2.12386734110477e-05 TTC9 other 8.73040745550985e-10 0.251274745126105 0.336265653698484 4.14635925480905 -4.28915228820523 8.67123443198383e-32 98.2171722706222 10.0976393161864 9.72674594478543 1.01959131273909e-20 -60.3051392821201 19.6570844852465 -3.06785776534571 0.00226372177056418 MED6 other 1.20625542183327e-27 1 1.41101241769962e-16 9.72674594478543 -3.06785776534571 3.45100486499898e-19 347.730736392239 45.6523473026989 7.61693005808886 1.18007412805189e-13 -163.811376664918 87.9683964408289 -1.86216167729174 0.0631262705994365 EIF2S1 essential 4.00903235166931e-15 1 1.46706815599411e-09 7.61693005808886 -1.86216167729174 0.985300857890935 -0.0496062690182732 116.951631456917 -0.000424160555952118 0.999661724059229 -31.239857036924 236.847670759973 -0.131898519148129 0.895113238224537 LOXL2 other 1 1 1 -0.000424160555952118 -0.131898519148129 4.47169571928069e-62 126.741438143152 21.4699347042946 5.90320557042964 6.29142649858618e-09 -471.065764021294 44.2520362638777 -10.6450641324684 3.69383244943451e-24 ELP3 essential 6.88506989897649e-58 5.74354007562572e-20 6.7897074772742e-05 5.90320557042964 -10.6450641324684 0.000313194566751781 -8.32978234089319 22.8143484520084 -0.365111559438811 0.715171352875642 -154.923206243438 46.265589187782 -3.34856226762051 0.000869088381918713 PEBP4 other 1 1 1 -0.365111559438811 -3.34856226762051 0.00415006398829016 5.89993246975393 21.4306785664524 0.275303110513248 0.783188878163953 117.116842500216 43.3336554246923 2.70267627672787 0.00709528579237448 ADAMDEC1 other 1 1 1 0.275303110513248 2.70267627672787 3.9368556703735e-09 107.662451331863 44.6991552314198 2.40860147746562 0.0163483254768089 -400.420065635579 93.8903714734861 -4.26476175726554 2.36332517431978e-05 CTIF other 3.12153286103915e-05 0.2784706052901 1 2.40860147746562 -4.26476175726554 0.100091265429664 -2.37507265659565 2.42138106864065 -0.980875206862421 0.327091103082939 6.41256108252277 4.95425186074595 1.29435508382839 0.196092978712633 MRO other 1 1 1 -0.980875206862421 1.29435508382839 1.06220348393875e-17 269.3283392231 55.2446170237626 4.87519605950482 1.43219785215341e-06 -563.810880573376 114.941035758856 -4.90521837436928 1.23761073218087e-06 MBD2 other 1.18934924096622e-13 0.0156508253191592 0.0136445489374655 4.87519605950482 -4.90521837436928 2.54277982467727e-33 231.747870623282 28.113500208368 8.24329481941571 1.27450224134778e-15 -318.299359725521 57.9814051424572 -5.48967999211948 6.19906448522274e-08 IER3IP1 other 3.58379388490014e-29 0.000826211314590486 1.64678434604547e-11 8.24329481941571 -5.48967999211948 1.69059264715522e-49 58.4512177952516 7.62097089690016 7.66978624981059 8.17017481482919e-14 -171.982245524951 16.4101837229939 -10.4802145075298 1.66567859352065e-23 MRPS36 other 2.55228771941024e-45 2.58713199145627e-19 1.01939271164624e-09 7.66978624981059 -10.4802145075298 5.8075676506752e-05 172.35702996816 64.1493034902119 2.6868106213259 0.0074377340044355 599.252722588208 138.132249842951 4.33825354520414 1.71663865582916e-05 CCNB1 other 0.325514166820345 0.204348665589903 1 2.6868106213259 4.33825354520414 1.13998843713655e-24 80.8296751007888 14.9816040187259 5.39526174899281 1.02848224512943e-07 -214.874383859023 32.2597839223394 -6.6607508710009 6.76613880350279e-11 CDK7 essential 1.46636712668875e-20 9.69790674706055e-07 0.00104905189003201 5.39526174899281 -6.6607508710009 4.37230078356195e-06 -17.9811755205353 10.0774631580091 -1.78429583304848 0.0749432669235097 78.9400680117788 22.2430613795165 3.54897496638993 0.00042083219702882 CD180 other 0.0274580489207691 1 1 -1.78429583304848 3.54897496638993 4.12347817624954e-19 59.4071674114974 6.60990681622973 8.98759529644671 4.11727149167402e-18 88.8268499596234 20.2364404729987 4.38945031257568 1.36471072533086e-05 IRAK2 other 4.78488407571996e-15 0.16350599200189 5.54061224634573e-14 8.98759529644671 4.38945031257568 2.48483709585852e-05 33.8794260781577 9.52232716710771 3.55789351527271 0.000406806454651301 -70.8607948858076 28.7073392709484 -2.46838601853701 0.0138816152896016 CAMK1 other 0.145288424994848 1 1 3.55789351527271 -2.46838601853701 4.66542119145353e-31 273.123544557516 24.7672557861472 11.0276062441395 1.21330103253437e-25 -255.244463072952 63.7563934427007 -4.00343321336621 7.11639182707902e-05 THUMPD3 other 6.44807862870793e-27 0.811268668287008 1.7437562439584e-21 11.0276062441395 -4.00343321336621 3.24303773915907e-41 404.56325241883 27.592975735189 14.6618203234563 2.79295638928868e-41 -66.6162880285011 84.3763643028051 -0.789513610582133 0.430154593566141 VHL ts 4.77342724826824e-37 1 4.23104963413343e-37 14.6618203234563 -0.789513610582133 1.36903581830896e-13 -164.315687679327 404.615406394412 -0.406103388755185 0.684830238099333 -8320.36822738736 1058.74997329678 -7.85867148735697 2.17286831699525e-14 BHLHE40 other 1.34001225896081e-09 3.24517883143241e-10 1 -0.406103388755185 -7.85867148735697 8.40274262472913e-28 587.982150851462 62.2454731008813 9.44618333767852 1.08425381573528e-19 -872.016292236099 162.863802578716 -5.35426705277026 1.27717675139474e-07 ARL8B other 1.12495918259874e-23 0.00168216949926201 1.48586142908362e-15 9.44618333767852 -5.35426705277026 2.5582519307942e-13 269.585439922388 59.1627720680554 4.55667357189216 6.44164578025292e-06 -843.622437658058 154.794111126136 -5.44996467579199 7.69438285878759e-08 EDEM1 other 2.47817864536034e-09 0.00102281431341863 0.0588573174941709 4.55667357189216 -5.44996467579199 0.326026062716839 -1.40330863788642 32.1999958681546 -0.0435810191911943 0.965255143461134 -111.578579946286 75.7550199221194 -1.47288694611915 0.14138770336448 CHL1 other 1 1 1 -0.0435810191911943 -1.47288694611915 0.471507967442124 -11.3408089043327 15.0783946302317 -0.75212309947073 0.452302329051024 11.6954062096152 26.0286086399401 0.449328904644906 0.653373368301579 MEIS2 other 1 1 1 -0.75212309947073 0.449328904644906 6.51518438623887e-27 65.1163074847278 7.5922287003385 8.57670521461301 1.02372438470286e-16 -34.9532701173119 13.7729580446758 -2.53781867365985 0.01143300920315 DPH6 other 8.63392234864375e-23 1 1.3491663665999e-12 8.57670521461301 -2.53781867365985 2.28637613528199e-21 60.3348124480813 9.87093514766018 6.11237046394567 1.88212708394602e-09 -73.7549255219479 18.2232615986847 -4.04729554709742 5.93848342559493e-05 KATNBL1 other 2.78137656857054e-17 0.680965894412971 2.0710926431742e-05 6.11237046394567 -4.04729554709742 1.01133519947883e-35 203.610320652982 32.5533068468779 6.25467396018201 8.0975717583616e-10 -448.800930841865 59.948689395678 -7.48641772432511 2.89153951872849e-13 EMC7 essential 1.45035580957258e-31 4.27196048496947e-09 9.04660716844158e-06 6.25467396018201 -7.48641772432511 0.0016821665492917 554.756686398272 250.340091603671 2.21601215708006 0.0271060453734364 -956.267399788511 569.926185036806 -1.67787939016481 0.0939481969943597 GSTM1 other 1 1 1 2.21601215708006 -1.67787939016481 6.8067356661386e-16 173.769063367505 30.2619041339616 5.74217215804645 1.56264315458649e-08 -262.68909118161 70.9688249625659 -3.70147161546174 0.000236394774583322 PRPF38B essential 7.23487933953872e-12 1 0.000165952703017085 5.74217215804645 -3.70147161546174 0.526375427284215 15.3927536574309 13.8590541113867 1.11066408527723 0.267207265177978 21.0601709932527 32.6334396605062 0.645355537520621 0.518970913359163 TSPAN2 other 1 1 1 1.11066408527723 0.645355537520621 0.638763351254586 -174.088866274829 259.685639192553 -0.670383109424642 0.502898608835141 -524.40247583473 591.851883106693 -0.886036677085634 0.375989982223113 GSTM5 other 1 1 1 -0.670383109424642 -0.886036677085634 1.96872237532515e-05 393.84908215923 343.588554373259 1.14628114687246 0.252183723854981 -2874.79331702543 780.412868355218 -3.68368261672092 0.000252911451034153 GSTM3 other 0.116607426290509 1 1 1.14628114687246 -3.68368261672092 0.327566247949888 -0.148813518580097 0.909209643240011 -0.163673493441835 0.870049310823432 -7.4537200779626 4.98612893457523 -1.49489116221532 0.135525898556577 SYT6 other 1 1 1 -0.163673493441835 -1.49489116221532 2.07967846497033e-05 764.59027092441 369.148873437057 2.07122471702404 0.0388220693194108 -2306.23917148903 782.363650049827 -2.94778415554218 0.00334192906187524 VAV3 other 0.12270102943325 1 1 2.07122471702404 -2.94778415554218 7.7666442209661e-20 137.150803475322 14.8031520909574 9.26497293499406 4.68004886377937e-19 25.1718704377596 35.7371676748712 0.704361091700596 0.481513269171202 PSRC1 other 9.16774683842838e-16 1 6.36861049383097e-15 9.26497293499406 0.704361091700596 0.977181522678484 -8.87754203188235 202.414875226053 -0.04385815035564 0.965034844709053 -156.785599820748 729.800465703887 -0.2148335157193 0.829984019858926 HMGCS2 other 1 1 1 -0.04385815035564 -0.2148335157193 0.894289879712139 1.97796066659307 4.55576054643257 0.434166951145387 0.664340307113899 -3.7804853550468 24.8569144369434 -0.152089888897396 0.879172739755037 PTPN22 other 1 1 1 0.434166951145387 -0.152089888897396 1.6566859210167e-17 1060.99333643771 146.533569043513 7.24061621758935 1.54593277953584e-12 -803.074252568682 352.822358035883 -2.27614331767208 0.0232281029095185 SORT1 other 1.84422276727579e-13 1 1.87274296912971e-08 7.24061621758935 -2.27614331767208 2.00851626852207e-06 2.53143335984316 9.18650673997401 0.275559952384068 0.782990710100323 -92.2640467080136 20.1227742854921 -4.58505598676487 5.63656864615889e-06 WNT2B other 0.0130633898104676 0.0690592390527387 1 0.275559952384068 -4.58505598676487 2.60538709826295e-14 665.271888982533 88.0877531921095 7.55237663437333 1.85958745741244e-13 -226.493147566172 302.667474854393 -0.748323379230401 0.454593958613138 PTGFRN other 2.61893511117392e-10 1 2.3021692722766e-09 7.55237663437333 -0.748323379230401 1.58253599716757e-21 300.629243685032 39.1962812699328 7.66984096309267 7.99420943788054e-14 -243.759092200269 84.8168116668266 -2.87394783427833 0.00421224019923577 LAMTOR5 other 1.93085217014416e-17 1 9.97837222036249e-10 7.66984096309267 -2.87394783427833 1.22130364317756e-07 1075.51463296097 200.796565486931 5.35624018445162 1.31145542569704e-07 -605.312317637814 720.920085869098 -0.839638580617554 0.40152220380506 NOTCH2 og 0.000878117319444665 1 0.00132968465611423 5.35624018445162 -0.839638580617554 6.39696552445175e-08 61.413267500574 16.2815269666742 3.77195994124369 0.000180076828329038 -181.235206778103 56.4910745258347 -3.2082095853075 0.00141576465701646 TRIM45 other 0.000469537269494758 1 1 3.77195994124369 -3.2082095853075 4.41627582004111e-14 118.699164647082 30.0484375957203 3.95026078374165 8.83607829803324e-05 -320.755789254538 67.5426400913023 -4.74893769063438 2.62013571192804e-06 CEPT1 other 4.40170210983498e-10 0.0326495111063353 0.733482859519739 3.95026078374165 -4.74893769063438 1.28994720116353e-17 16.4323275051589 1.8061296309933 9.09808865497757 1.79570800514148e-18 10.3048539915601 6.19844837297982 1.66248928304072 0.0969993374363644 CD101 other 1.44112901313989e-13 1 2.42743808135025e-14 9.09808865497757 1.66248928304072 1.75198512342269e-25 2774.19297519404 258.763513032167 10.7209588503661 2.01946492659076e-24 -260.550047932423 897.816828187392 -0.290204014618939 0.771772823223887 VTCN1 other 2.27950784408527e-21 1 2.88177645024502e-20 10.7209588503661 -0.290204014618939 0.272746492990712 1.73450640397325 1.62001218336622 1.07067491330165 0.284795712510977 -2.70480658977173 3.83470810563708 -0.705348755436072 0.480898496602814 NGF other 1 1 1 1.07067491330165 -0.705348755436072 6.16944574303953e-132 119.938787091665 3.61586345929242 33.1701648698692 1.76188898142452e-132 -15.4160614775788 19.7286946289754 -0.781403015632743 0.434907311456718 AP4B1 other 9.65765036615408e-128 1 2.75841338931823e-128 33.1701648698692 -0.781403015632743 2.4243355193036e-18 88.2478800435118 20.6240582774351 4.27888046360228 2.22429127634211e-05 -266.887923109735 46.9347820474631 -5.68635692906473 2.1330785289397e-08 NAPG other 2.76059085583101e-14 0.000288456209468516 0.194936887458622 4.27888046360228 -5.68635692906473 4.29606288050307e-11 187.727544434963 42.7716832342579 4.38906141258905 1.37494808882603e-05 -337.618632319445 102.751534185813 -3.28577704454423 0.00108443218527707 SPIRE1 other 3.7762392719622e-07 1 0.12257662211884 4.38906141258905 -3.28577704454423 8.9794264176268e-18 118.233036953155 18.5848065050541 6.36181156478555 4.33845724468747e-10 -298.011521888672 58.4778247765468 -5.09614581300557 4.84157002390474e-07 PPHLN1 other 1.00803040964278e-13 0.00623352140577735 4.8999818139683e-06 6.36181156478555 -5.09614581300557 0.380593278954808 -32.4855030443608 25.6029659680647 -1.26881795979735 0.205049630173383 18.3983763409682 79.7643020670036 0.230659278200833 0.817666389039675 FKBP11 other 1 1 1 -1.26881795979735 0.230659278200833 2.22854355482419e-32 1355.72369211081 150.763273312532 8.99240022004824 4.01968253061401e-18 -3152.33495367741 469.692741384371 -6.71148322281121 4.85830630964427e-11 ARF3 other 3.11594959835518e-28 6.98041450569689e-07 5.41072428029825e-14 8.99240022004824 -6.71148322281121 3.38912922768803e-09 527.790083322882 83.0642755922843 6.35399610192842 4.49219684695099e-10 472.486524997205 237.64241426768 1.98822473022428 0.0472959756258282 TMEM106C other 2.69740795231691e-05 1 5.0685457024148e-06 6.35399610192842 1.98822473022428 0.00147278744414617 205.136169925699 146.965887229256 1.3958080599051 0.163355637842502 -1277.90581579396 439.193560387956 -2.90966428256629 0.00376986091863589 SLC38A2 other 1 1 1 1.3958080599051 -2.90966428256629 8.06464881836683e-06 17.9533298300809 3.99466836639192 4.49432297837949 8.5762093173692e-06 35.2494250701885 11.7710395237616 2.99458896548875 0.00287653886303012 PLEKHA8P1 other 0.0494282326077703 1 0.0777068524982663 4.49432297837949 2.99458896548875 4.458937315936e-29 2319.92476937031 193.92833009635 11.9627945448594 2.04992448367281e-29 318.834000746268 590.46554051819 0.539970546742594 0.589440360544928 YWHAQ other 6.05211561891993e-25 1 3.00518929306433e-25 11.9627945448594 0.539970546742594 2.91329953478232e-05 192.539040531636 61.1181941905633 3.15027371278852 0.00172134599893561 -490.770482972264 188.10625413748 -2.60900672985375 0.00933174834169525 KIDINS220 other 0.169175303984809 1 1 3.15027371278852 -2.60900672985375 1.90286739398415e-20 453.235451043853 46.917476434595 9.66026916805049 1.78679624626216e-20 -0.545131758791249 140.960608930245 -0.00386726308100025 0.99691580375847 GRHL1 other 2.27297510211407e-16 1 2.46828033458655e-16 9.66026916805049 -0.00386726308100025 1.38881657122598e-13 387.176809163918 50.4893075449674 7.6684911715037 8.09180786876445e-14 20.4642034411374 150.351589453442 0.136108993031126 0.891785562887183 ROCK2 other 1.35895701494462e-09 1 1.0098576220218e-09 7.6684911715037 0.136108993031126 0.504905500899081 82.0661582634423 76.8844107262615 1.06739659559374 0.286268859919549 -54.7952644259265 234.916065846048 -0.233254648755426 0.815651899579996 RSAD2 other 1 1 1 1.06739659559374 -0.233254648755426 1.8851571154447e-06 57.57965095342 11.3210981923455 5.08604818853629 5.04550917231283e-07 7.56349104772862 33.2299797410695 0.227610462199012 0.820034918900199 MYCN og 0.0122912243926994 1 0.00494762629436997 5.08604818853629 0.227610462199012 1.40224518043836e-06 272.374354242776 54.8071212774844 4.96968911875091 9.0120419066037e-07 483.904176485504 165.240830283484 2.9284782438779 0.00354976489930886 LPIN1 other 0.00924445593414474 1 0.00869481803149125 4.96968911875091 2.9284782438779 0.0183849239418586 91.1093045612627 33.6811113918576 2.70505635937205 0.00704453148977233 -25.0702397896654 102.910773546387 -0.24361142109543 0.807624129782545 CMPK2 other 1 1 1 2.70505635937205 -0.24361142109543 4.88597116701464e-35 294.900616912466 23.1546426638253 12.7361333618502 1.12585847633056e-32 -119.521960863677 70.5104860071866 -1.6950948381138 0.0906339217017792 IAH1 other 6.97228085532989e-31 1 1.67032363548402e-28 12.7361333618502 -1.6950948381138 1.57139142204776e-11 2997.27614559637 491.600282533505 6.09697807769686 2.0434501911563e-09 -1765.86275496322 1228.60586478128 -1.43728986291106 0.151207412286356 LDHA other 1.40906668815023e-07 1 2.24513872502343e-05 6.09697807769686 -1.43728986291106 0.691332190443552 135.274393730166 422.040145568604 0.320524943303471 0.748692609541339 -666.30603374569 1054.48567586363 -0.631877747604285 0.527730272980808 SAA2 other 1 1 1 0.320524943303471 -0.631877747604285 0.029428287357416 21.0831878632883 9.54074419624245 2.20980538096722 0.0275413411058674 -16.2492806668875 24.5944037939232 -0.660690163625856 0.509095412643479 ANO3 other 1 1 1 2.20980538096722 -0.660690163625856 8.16158268638268e-15 -419.794040746369 935.293823940236 -0.448836536712974 0.653729973796775 -16463.6595703628 2128.48123581298 -7.7349329152411 5.11928675164161e-14 IL6ST og 8.3688868866168e-11 7.6205702584937e-10 1 -0.448836536712974 -7.7349329152411 0.000420103689245674 -87.0489462393582 38.3169861275197 -2.27181088694339 0.0234971230671374 -352.054684067174 90.4231034914789 -3.8934151834365 0.000111438100674389 FST other 1 1 1 -2.27181088694339 -3.8934151834365 0.0228589388972568 94.9353928010037 47.7323997736993 1.98890885962355 0.0472117358265719 -655.097659790431 350.511216647039 -1.86897773502669 0.0621630405659521 NAV1 other 1 1 1 1.98890885962355 -1.86897773502669 1.54260450379311e-16 215.526247016758 24.6128939361109 8.75663981554595 2.74265244099974e-17 -80.9952531656243 170.625840650581 -0.474695115679996 0.635200945029105 CDC73 ts 1.67033215670718e-12 1 3.64909907275015e-13 8.75663981554595 -0.474695115679996 7.88500611549592e-26 285.383911968126 25.1515523429844 11.3465724928795 6.20421034508553e-27 98.1646589293339 183.914852420543 0.533750578799742 0.593731729774547 TIMM17A other 1.0311222497234e-21 1 8.98493742175286e-23 11.3465724928795 0.533750578799742 0.964380646143784 0.0615537742364399 2.98189814657864 0.0206424804640176 0.983538464075773 4.39141372657876 16.5616766180922 0.265155142673267 0.790990948621369 ERN2 other 1 1 1 0.0206424804640176 0.265155142673267 5.44119406536738e-11 1243.56872501632 194.685107475316 6.38759040762269 3.62004836913553e-10 -1033.39380147418 1008.55828134251 -1.02462477438449 0.305995670390009 RPS15A essential 4.75560361313109e-07 1 4.10115279739365e-06 6.38759040762269 -1.02462477438449 8.58246092707736e-43 1478.22414019751 113.052731473178 13.0755278615114 3.68437236571705e-34 -361.540979420864 235.312585377905 -1.53642857155405 0.125015766213997 NARS essential 1.27183488478359e-38 1 5.49303076004754e-30 13.0755278615114 -1.53642857155405 0.000181514563408865 -29.1727965155852 9.36616255082077 -3.11470106965298 0.00193867813288321 -78.9042545114783 20.528711055087 -3.84360490533214 0.000135612324332685 GRP other 0.953132972459948 1 1 -3.11470106965298 -3.84360490533214 4.83104002550245e-29 225.925719936031 26.2252579966763 8.61481400734605 7.73762350348334e-17 -248.877131183492 58.472365974519 -4.25632052056774 2.45053252777251e-05 KIAA1468 other 6.55282269059153e-25 0.288525699819935 1.02237219351525e-12 8.61481400734605 -4.25632052056774 4.14293211617554e-37 350.128112966409 26.5274693449869 13.1987001252562 1.05269237358783e-34 -308.672590398274 115.083808535751 -2.68215480809696 0.00753729011478809 FBXO18 other 5.98239397575747e-33 1 1.57166971376663e-30 13.1987001252562 -2.68215480809696 1.9638987621422e-39 491.530889273623 34.1300071528634 14.4017224219183 4.42114294129765e-40 45.0182453697929 147.862906730724 0.304459356069446 0.760894171761698 RBM17 essential 2.8684705319849e-35 1 6.68344178435966e-36 14.4017224219183 0.304459356069446 6.24559988336917e-05 13.0486956694933 5.55629628023183 2.34845210035287 0.0192086452517703 97.9602312392011 24.0441122712855 4.07418789822361 5.30516845090307e-05 IL2RA other 0.348566929490833 0.611049302175016 1 2.34845210035287 4.07418789822361 3.74798496978916e-14 32.266644219982 4.93335778698677 6.54050357042724 1.41567582261887e-10 -80.0870394309242 21.402328115525 -3.74197792869225 0.000201982572275589 ANKRD16 other 3.74648577580124e-10 1 1.6232138982148e-06 6.54050357042724 -3.74197792869225 3.27933860905597e-06 53.4579716556499 12.4975306180788 4.27748275153797 2.23442547090761e-05 -156.879398457887 71.1332081886625 -2.20543122477768 0.0278428704015955 ECHDC3 other 0.0208729902466412 1 0.195780359760924 4.27748275153797 -2.20543122477768 1.5128880633284e-05 38.0327568951007 8.01773108279334 4.7435810084379 2.6863849186335e-06 37.9203516057448 34.6956347525109 1.09294301361645 0.274902571561526 IL15RA other 0.0905789530627043 1 0.0251687403026773 4.7435810084379 1.09294301361645 8.31061360712885e-40 67.4660226727896 17.807963565487 3.78853103695378 0.000168512093020053 -447.566667622382 39.2313418020774 -11.4083956108451 3.615682651817e-27 CCNH essential 1.21634140753938e-35 5.64408061948633e-23 1 3.78853103695378 -11.4083956108451 6.14722583469925e-19 125.821301382421 25.7929364776154 4.87813016139576 1.42434983425606e-06 -342.742054887926 58.8643626212969 -5.82257310918242 1.01328052584572e-08 TMEM241 other 7.09328389065946e-15 0.000138495182272593 0.0135740539204602 4.87813016139576 -5.82257310918242 1.58284988327869e-07 66.7545798875546 30.6168519647542 2.18032147669531 0.0296727917394923 -276.299571199647 68.7922794113648 -4.01643285502182 6.76254477341702e-05 KCTD1 other 0.00112952167670768 0.771876860437819 1 2.18032147669531 -4.01643285502182 2.55964053991145e-11 258.460523485025 54.2190766427625 4.76696652707616 2.43107795187158e-06 -401.034679770304 124.479868245222 -3.22168303536662 0.00135419561375062 CABLES1 other 2.2750085118733e-07 1 0.022869150293256 4.76696652707616 -3.22168303536662 0.404866098585263 -21.8673005788705 21.8597642101552 -1.0003447598356 0.317589259585272 26.5379744519062 56.4032237893842 0.470504568160889 0.638183501452323 DOCK2 other 1 1 1 -1.0003447598356 0.470504568160889 0.15527394161194 193.58262893944 195.996176120048 0.987685743526294 0.323749738344979 -785.744329847968 626.095252043806 -1.25499167623937 0.210025641270264 EMP1 other 1 1 1 0.987685743526294 -1.25499167623937 0.186600739927312 -4.00037843772743 6.78599098118801 -0.589505416204825 0.555775392914678 -46.9607859523437 25.627567288963 -1.83243245146285 0.0674521717136522 SOX5 other 1 1 1 -0.589505416204825 -1.83243245146285 0.00201234344435864 171.485082915898 125.602368407949 1.36530134813162 0.172730017108731 -1096.21556222728 406.37077218567 -2.69757481900401 0.00720424440295177 RERG other 1 1 1 1.36530134813162 -2.69757481900401 8.33386511963954e-05 12.4908048744835 3.01628122854456 4.14112741089154 4.00457689709704e-05 27.2156210872619 10.8286587182745 2.51329567172827 0.0122482402371157 KLRD1 other 0.457695872370604 1 0.343192240081217 4.14112741089154 2.51329567172827 0.0081265476771146 2.41408925352409 0.811016149211174 2.9766229141949 0.00304363014420472 5.0287955089109 2.91734604706814 1.72375694476311 0.0853178046910786 KLRC1 other 1 1 1 2.9766229141949 1.72375694476311 0.081713584144366 31.3381483210481 14.1486569858347 2.21492035268246 0.0271908173660132 16.5036803341017 49.9474220079346 0.330421064203873 0.741212647396403 SPX other 1 1 1 2.21492035268246 0.330421064203873 0.0760829854453145 33.9672143971477 17.1986505097872 1.974993001795 0.0487778390161023 -18.448161556579 49.6178249103481 -0.371805124265566 0.710183797459221 LRP4 other 1 1 1 1.974993001795 -0.371805124265566 3.13928491725843e-09 22.8743396616733 18.2698709518604 1.25202524538598 0.211102682293695 -288.207618135471 53.1295621611164 -5.42461873225071 8.77818686061514e-08 DDB2 ts 2.50295186453015e-05 0.00116425092332339 1 1.25202524538598 -5.42461873225071 2.23544978859017e-11 134.610550879481 37.8917747134319 3.55250055975245 0.000414976765027305 -500.852125437848 109.119059075278 -4.58996008288823 5.51924654619943e-06 ACP2 other 1.99178576163384e-07 0.0676604434098588 1 3.55250055975245 -4.58996008288823 2.80919042810799e-07 20.7921992601394 5.25135277199049 3.95939868504744 8.52164538468619e-05 -11.8814534875891 10.6600945487335 -1.11457299306981 0.265530176714845 PIWIL4 other 0.0019639050282903 1 0.70874524664435 3.95939868504744 -1.11457299306981 5.78764622856264e-13 146.137266230422 77.4645138635449 1.88650594887674 0.059765075465285 -785.018541723916 132.972623158452 -5.90361025508595 6.30243162630719e-09 PUM1 other 5.51331179732877e-09 8.66395275668449e-05 1 1.88650594887674 -5.90361025508595 0.0571178344970456 42.4745896579613 17.7329899099793 2.39523001330185 0.016953405826058 28.9102856942865 32.9891896383797 0.876356346160507 0.381230389537005 SPOCD1 other 1 1 1 2.39523001330185 0.876356346160507 1.03963289177758e-15 615.515054843509 80.2063870343067 7.6741401477196 7.86004241601685e-14 -44.0564544312618 149.067175314203 -0.295547657211588 0.767689370411895 YARS essential 1.0988919666089e-11 1 9.81247695215544e-10 7.6741401477196 -0.295547657211588 6.44886826291959e-12 292.079265272949 40.0647853527707 7.29017421911009 1.10455211247445e-12 118.29980491081 83.0059199486266 1.42519720260949 0.154676861257107 CDCA8 essential 5.90071446057143e-08 1 1.34103671975523e-08 7.29017421911009 1.42519720260949 4.2791981061954e-21 479.291426701184 54.7981237188224 8.74649338653458 2.80128254853127e-17 -229.160189222378 113.043834775299 -2.02717989599246 0.0431347326053225 GNL2 essential 5.18039722736015e-17 1 3.72626604605629e-13 8.74649338653458 -2.02717989599246 1.4221353746e-06 43.2107330421729 25.2185233580863 1.71345214898625 0.0872065257913474 -189.118155286015 48.6154366873972 -3.89008447053693 0.000112787468821796 AGO4 other 0.00936618357711561 1 1 1.71345214898625 -3.89008447053693 3.09054888263393e-05 167.644058948856 55.560414593339 3.01732915738455 0.00267104276768057 -250.708428384614 112.814646307693 -2.22230389927231 0.0266785933053093 HOOK1 other 0.179035496770983 1 1 3.01732915738455 -2.22230389927231 0.0384907461998221 26.3193927470642 25.6032079588297 1.02797246303612 0.30442558038438 -96.0221938704879 51.9869563853827 -1.84704396154045 0.0652906844954838 CYP2J2 other 1 1 1 1.02797246303612 -1.84704396154045 4.17730497439392e-24 382.542621809413 39.8785647413658 9.59268780836046 3.15095303572633e-20 -143.569504224352 83.170004985959 -1.72621733338347 0.0848802973898593 BTF3L4 other 5.32648157284969e-20 1 4.34264347383803e-16 9.59268780836046 -1.72621733338347 1.38703837503129e-15 296.97140022837 36.1974447418654 8.20420895303963 1.69716973228085e-15 43.48601295218 75.2302378176434 0.578039020128971 0.563477850328857 ZCCHC11 other 1.45985788972043e-11 1 2.18985810556198e-11 8.20420895303963 0.578039020128971 1.92263973764746e-22 282.935765780189 37.0860945192651 7.62916045617079 1.07200198394262e-13 -323.546966806901 77.2339920648038 -4.18917834177763 3.26891736760063e-05 PRPF38A essential 2.38830308210567e-18 0.381417278451641 1.33410646901659e-09 7.62916045617079 -4.18917834177763 1.07473066745071e-11 1912.21860252395 262.98688499431 7.27115575579111 1.25864058748138e-12 1444.64652899093 627.916613497472 2.3006980512019 0.0217888698573986 DSC2 other 9.72308834842661e-08 1 1.52673103261492e-08 7.27115575579111 2.3006980512019 0.000991468293083726 591.592530377619 158.150164407946 3.74070133023456 0.000202985293982134 555.184012802919 386.879956502408 1.43502914398064 0.151853450681823 DSG3 other 1 1 1 3.74070133023456 1.43502914398064 1.42409064985799e-30 242.908882619509 20.4419933356185 11.882837384369 4.21798526752928e-29 8.77445074515171 53.3289388174477 0.164534508649945 0.869371724895371 RNF138 other 1.95883668887966e-26 1 6.17344323755585e-25 11.882837384369 0.164534508649945 2.7714685369386e-07 -94.4399175438782 499.058349937363 -0.189236223691541 0.849978913582427 -5630.3914496299 1079.64149291673 -5.21505655957979 2.62393520937684e-07 ELP2 essential 0.00193864224158855 0.00341085337866896 1 -0.189236223691541 -5.21505655957979 0.00772115997790511 220.343733315702 73.5051164519317 2.99766525041553 0.00284529107205917 36.6020505971405 178.264092072735 0.205324864764162 0.837395408600932 DSG1 other 1 1 1 2.99766525041553 0.205324864764162 2.24253796257576e-06 700.168043974374 135.889463008837 5.15248223424683 3.60801476348792e-07 490.555337590164 323.033085599607 1.51859162252562 0.129449469364793 DSC3 other 0.0145069780799026 1 0.0035701306084713 5.15248223424683 1.51859162252562 2.44973641537674e-05 9.74177667579186 2.10783377336637 4.62170062880883 4.76585868931451e-06 5.77354831769597 5.11543398011931 1.12865268912361 0.259545539951409 DSC1 other 0.143309580299539 1 0.0439126219633439 4.62170062880883 1.12865268912361 3.82431091259628e-12 337.926132375534 48.4779505537773 6.97071820312757 9.19835585843772e-12 27.9206574870749 105.247163681691 0.265286555099175 0.79088958704671 DTNA other 3.53098626560015e-08 1 1.09248872530665e-07 6.97071820312757 0.265286555099175 0.133353562056528 17.8012922578932 21.2790299639176 0.836565026135049 0.403205787647616 -62.8951561320853 46.0831204293087 -1.36481982005898 0.172875990549305 FHOD3 other 1 1 1 0.836565026135049 -1.36481982005898 1.11662253801172e-23 507.891107517854 54.9897999857028 9.23609665155909 5.69533585992559e-19 -186.173915910311 118.218049762063 -1.57483494512913 0.115875899541169 TPGS2 other 1.41420244439184e-19 1 7.74451770232682e-15 9.23609665155909 -1.57483494512913 6.44398402010402e-07 32.1955138482217 11.053774480005 2.91262626231968 0.00373868091053591 -89.8671228316453 28.4019055001812 -3.16412301389679 0.00164686998132689 DAGLA other 0.00437675394645465 1 1 2.91262626231968 -3.16412301389679 0.00056977763114994 250.636136968661 86.6378180650462 2.8929183879087 0.00397526428409787 -266.45175481629 224.147962863043 -1.18873154773704 0.23508273384753 SLC43A3 other 1 1 1 2.8929183879087 -1.18873154773704 7.97158789279979e-13 89.7347704147106 17.8018830577884 5.04074597745721 6.40859081228332e-07 -147.640516164845 46.3002342284367 -3.18876391502502 0.00151472371939759 TIMM10 essential 7.55626816358492e-09 1 0.00623876315575781 5.04074597745721 -3.18876391502502 4.1373578402361e-09 88.6378502625402 19.7104530832264 4.49699709531137 8.42007127954058e-06 -158.232856493375 57.341871134676 -2.759464477916 0.0059836193377928 DHX34 other 3.27595993789894e-05 1 0.076353206362874 4.49699709531137 -2.759464477916 0.0986610455647399 -78.8087081401788 36.5871500300382 -2.15399964401372 0.0316819865392665 -77.7863745436773 96.9187183022986 -0.802593925159578 0.422562565278155 APLNR other 1 1 1 -2.15399964401372 -0.802593925159578 7.44463289966782e-06 2288.9709641009 540.390157212001 4.23577471490273 2.69411139317152e-05 -1030.46879103666 1381.70173253637 -0.745796843682786 0.45612713912031 FADS2 other 0.0457621584342581 1 0.234414632319854 4.23577471490273 -0.745796843682786 0.36872471904746 -78.2645098124948 322.831921348816 -0.242431137185876 0.808539365488387 -1112.89988877227 814.626699701758 -1.36614708206804 0.172468908860517 TCN1 other 1 1 1 -0.242431137185876 -1.36614708206804 5.91812216916891e-08 -46.2579324171505 30.4356375365781 -1.51986080007547 0.129122696262382 -515.153914226065 88.1550785045894 -5.84372361711692 8.76619158689854e-09 C5AR2 other 0.000435928878980982 0.000120070526165749 1 -1.51986080007547 -5.84372361711692 1.90688615146131e-16 381.575512924867 50.956024665647 7.48832970053321 2.90339894885757e-13 -222.048905037024 126.006061919327 -1.76220811645702 0.0786062193591103 TMEM165 other 2.06077186388423e-12 1 3.57843920446696e-09 7.48832970053321 -1.76220811645702 6.15495050800313e-17 240.077445387974 41.7861659475825 5.745381035655 1.54210678259136e-08 -460.737531777283 103.330474626135 -4.45887366185339 1.00485486308997e-05 CLOCK other 6.74767224192383e-13 0.121316127620852 0.000163864266718158 5.745381035655 -4.45887366185339 0.000103848463215262 666.632535666773 174.926499486483 3.81092937675967 0.000154718780696771 1412.78273535181 436.32778422996 3.23789313083767 0.0012796685892123 PDGFRA other 0.562547125237072 1 1 3.81092937675967 3.23789313083767 2.81245655307282e-28 37.8546885779375 4.3805875687645 8.64146372688859 6.25352993105224e-17 -51.0499703682011 10.4614174502798 -4.8798330255749 1.39824260057411e-06 GGACT other 3.78472278347009e-24 0.0176332374358401 8.27592151075453e-13 8.64146372688859 -4.8798330255749 7.56614896242296e-09 2516.20466493971 433.036864622023 5.81060152265785 1.06466017690546e-08 4154.76241512813 1021.42737498877 4.06760433180463 5.45814406031886e-05 COL4A2 other 5.90083957579367e-05 0.628123218461495 0.000113833466114732 5.81060152265785 4.06760433180463 1.80946552389799e-08 126.61579465302 22.4316635213071 5.64451203241133 2.68774305389546e-08 224.742259046835 56.2180250145031 3.99769040247955 7.29305131323082e-05 CLDN10 other 0.000137863178265788 0.830605614063858 0.000282777446700341 5.64451203241133 3.99769040247955 3.54683746133987e-12 97.0869256511082 15.2785240774236 6.35447018043904 4.47327251714384e-10 221.797323774349 38.3511474353614 5.78332953787563 1.24539515383154e-08 DZIP1 other 3.28153401923165e-08 0.000169797175273392 5.04808803559682e-06 6.35447018043904 5.78332953787563 1.4256805797896e-60 456.072480876669 28.2676889994429 16.1340561262598 4.89428895914953e-48 -280.696614244293 69.5917415122015 -4.03347592896606 6.29264886822923e-05 UBAC2 other 2.1926967317164e-56 0.720256589457518 7.48630439191513e-44 16.1340561262598 -4.03347592896606 7.26493137832868e-31 321.656221094638 31.879713083557 10.0896836885443 4.84797197668823e-22 -292.435313338846 77.1002469512734 -3.7929231734324 0.000165763394879265 ARGLU1 other 1.00183403707152e-26 1 6.78473678137517e-18 10.0896836885443 -3.7929231734324 4.53385301273722e-31 174.531870909361 14.3430970863125 12.1683531708026 2.99238198985415e-30 27.4533424105339 34.5341771140284 0.794961533899757 0.426987740636052 BIVM other 6.2680517901092e-27 1 4.40269162167241e-26 12.1683531708026 0.794961533899757 1.95549305464249e-50 304.452480322025 24.7695331711822 12.2914097015053 9.1549291588394e-31 -411.637142110248 59.6381269971115 -6.90224798860946 1.45101345009854e-11 ERCC5 other 2.96042093542326e-46 2.10237338784777e-07 1.34989430447087e-26 12.2914097015053 -6.90224798860946 1.75946967000919e-38 337.895820404336 27.8305119734488 12.1412003029876 3.67495015578583e-30 -211.292390880374 65.5292249731345 -3.22439935718757 0.00133867925309774 TPP2 other 2.55950052896237e-34 1 5.40621917417654e-26 12.1412003029876 -3.22439935718757 1.13662816180639e-20 62.9446208333011 6.29879902182893 9.99311465807404 1.12139179241204e-21 58.0575870960696 15.1657511426239 3.82820386211512 0.000144318241103943 KDELC1 other 1.36349914290294e-16 1 1.56523866384873e-17 9.99311465807404 3.82820386211512 1.01803717357582e-44 338.827362082431 23.6221505823215 14.3436289131102 7.93615936684032e-40 -47.9445063735098 55.2820905570418 -0.867270139215143 0.386174998270548 CARS2 other 1.5187078555404e-40 1 1.19915368032957e-35 14.3436289131102 -0.867270139215143 2.31172624675864e-08 239.732755755533 136.315975341649 1.75865488366049 0.0792014848246341 -1022.68402218164 267.469496928997 -3.82355384043336 0.000146846170683453 ARHGAP32 other 0.000174997676879629 1 1 1.75865488366049 -3.82355384043336 4.05291903149002e-41 1083.28567684657 140.301134838227 7.72114693224427 5.50752191704797e-14 -1467.6145631246 250.591371291163 -5.85660454134064 8.14999153649118e-09 STT3A other 5.96305977103127e-37 0.000111760833939904 6.90147571425281e-10 7.72114693224427 -5.85660454134064 0.000201467073390907 -15.9065475660765 9.40643730746588 -1.69102786168058 0.0914095692077145 -73.3440761148508 17.9690071593468 -4.08169886429702 5.1480536697505e-05 ADAMTS8 other 1 0.59341614651214 1 -1.69102786168058 -4.08169886429702 0.497321012204098 -120.698579276862 116.768750451521 -1.03365479899499 0.301760261767744 -226.472909070348 210.746332746963 -1.07462325022883 0.283023367951214 ETS1 other 1 1 1 -1.03365479899499 -1.07462325022883 0.425790254749026 -21.5110037172837 79.345803591683 -0.271104491271905 0.786413694660899 -169.902331682923 142.191194277364 -1.19488645233195 0.232653027768386 SLC37A2 other 1 1 1 -0.271104491271905 -1.19488645233195 0.291503780525864 36.8153633941946 26.6020123522143 1.38393152017051 0.166944868748399 2.33957800015504 53.8450243074243 0.0434502171787942 0.965358533008551 KLB other 1 1 1 1.38393152017051 0.0434502171787942 1.76033288645557e-18 258.485598478219 91.0482151277795 2.83899687781307 0.00469598395535485 -1477.23807643418 204.415166621304 -7.22665593190003 1.69788329932027e-12 TMED7 other 2.01065222290955e-14 2.48858755181372e-08 1 2.83899687781307 -7.22665593190003 1.02994709129439e-11 88.6896062287282 32.6739758146021 2.71438060467354 0.00685071804858955 -381.584246060874 72.9604655172094 -5.23001386238233 2.42194362264087e-07 APC ts 9.32720085876197e-08 0.00315191743050483 1 2.71438060467354 -5.23001386238233 0.153960195349662 -119.638740639082 82.0266915235291 -1.45853426996704 0.145270439114028 114.103239380856 182.83406616251 0.624080849787789 0.532836103012087 NREP other 1 1 1 -1.45853426996704 0.624080849787789 7.09789797353518e-09 40.3315264521465 21.8961982887285 1.84194196272455 0.0660287582294505 -235.197976068753 48.9938583153779 -4.80056039993345 2.04845041003482e-06 WDR36 other 5.54700726631774e-05 0.0256363568815858 1 1.84194196272455 -4.80056039993345 1.17582476990306e-11 118.07934023042 23.1882581033067 5.0922039811857 4.88038666144475e-07 -164.532080012499 51.0395148358306 -3.22362155168831 0.00134139640230928 OSTF1 other 1.06165218474548e-07 1 0.00479058754687417 5.0922039811857 -3.22362155168831 4.38373551711475e-12 72.5765839677009 20.6437825981621 3.51566306332649 0.000475111059453715 -234.051181783073 46.1567886892958 -5.07078565102498 5.43519566135873e-07 RFK other 4.03917390546953e-08 0.00698476994441211 1 3.51566306332649 -5.07078565102498 1.59136584075155e-17 677.670628180303 103.525853926889 6.54590715724867 1.38334051629838e-10 -927.99396060056 229.859920002018 -4.03721518998359 6.19614042546903e-05 UBQLN1 other 1.77262241001315e-13 0.709582001524713 1.5869682402975e-06 6.54590715724867 -4.03721518998359 1.04814258471681e-17 106.634235101961 18.3868573901913 5.79948127290346 1.1311460454123e-08 -199.388204199586 40.257687073831 -4.95279830244385 9.78857284958725e-07 NAA35 essential 1.17371006636588e-13 0.0124383395199705 0.000120829020570942 5.79948127290346 -4.95279830244385 0.000128437976854451 34.4097916991888 8.10832869567014 4.24375885471486 2.58413472937502e-05 31.8369783785705 17.6629098033195 1.80247641714092 0.0720238449460821 C9orf40 other 0.689455059754694 1 0.225103976275858 4.24375885471486 1.80247641714092 0.0470358010789437 810.069314498525 332.05180199367 2.43958716572171 0.0150230513775087 276.693631868058 730.425303501861 0.378811673885765 0.704975787585317 ANXA1 other 1 1 1 2.43958716572171 0.378811673885765 0.00371534250161556 292.451019146221 92.7954425954315 3.15156661756812 0.00171371312702884 441.009672967969 202.684628055518 2.17584173599574 0.0299983475000016 CTSL other 1 1 1 3.15156661756812 2.17584173599574 0.0185368897554041 -98.3585934383869 83.2258154175281 -1.18182793337549 0.237789384811432 -525.75924238517 186.578163607297 -2.81790340423635 0.00500932656191234 TMEM2 other 1 1 1 -1.18182793337549 -2.81790340423635 1.03634950927741e-09 143.664848278868 22.0184831543869 6.52473866031252 1.5654118656707e-10 68.2125284770127 48.4110866769444 1.40902700516117 0.159400626756662 AGTPBP1 other 8.47407027298181e-06 1 1.79208350381982e-06 6.52473866031252 1.40902700516117 0.000217310940487027 481.014517569073 482.315280886409 0.997303084996716 0.319063268741061 -3683.54717302926 1056.60290372949 -3.48621715880908 0.000529692605920241 GOLM1 other 1 1 1 0.997303084996716 -3.48621715880908 0.0539729371561135 -35.6987718304739 29.2972973400855 -1.2185005127292 0.223565900660148 -156.954681852332 66.2083196454089 -2.37061871820539 0.0181085058558613 FAM189A2 other 1 1 1 -1.2185005127292 -2.37061871820539 4.54766450765346e-07 267.789207956763 62.7414842232248 4.26813632594359 2.32761270531116e-05 639.584149691072 138.215807946547 4.62743125546409 4.638920547829e-06 PSAT1 other 0.00312560981611022 0.0570865562615837 0.203596283333568 4.26813632594359 4.62743125546409 1.34278745993509e-26 84.4430289382223 16.369802964986 5.15846336812 3.49989991897321e-07 -291.606985100882 35.861151474397 -8.13155665983212 2.91044306354367e-15 ISCA1 other 1.77288228335229e-22 4.38079889924594e-11 0.00346665086974297 5.15846336812 -8.13155665983212 0.00122442059259539 -32.1618117237407 22.3177626368968 -1.44108584032386 0.15013366534414 137.080940664851 50.9633283810109 2.68979568288808 0.00736831943762816 ADAM19 other 1 1 1 -1.44108584032386 2.68979568288808 0.956527475559132 0.0972776788537083 18.7733132166574 0.00518170009369441 0.995867512628528 12.0786631811262 42.8694641943338 0.281754470416794 0.778238539965514 HAVCR2 other 1 1 1 0.00518170009369441 0.281754470416794 0.268454093973163 -8.64602587372741 9.85408573979836 -0.877405180148587 0.380652498535676 22.8190797223885 23.1806425986837 0.984402379064518 0.325353715758432 CCNJL other 1 1 1 -0.877405180148587 0.984402379064518 7.25498021809881e-05 53.7435501245414 36.7494959985684 1.46242958343252 0.144203114284235 -289.956122072361 82.2336840118762 -3.52600185138836 0.000457611279689509 TAOK3 other 0.401780804478312 1 1 1.46242958343252 -3.52600185138836 1.01860274476865e-28 82.4350962703377 13.0035856704581 6.339412709651 4.8415658507829e-10 -235.669659731735 30.0124421506627 -7.85239863349576 2.18102959414965e-14 USP30 other 1.37694719037826e-24 3.25693149294367e-10 5.45644471383233e-06 6.339412709651 -7.85239863349576 0.660294701412037 -23.6723122564028 31.6302102520455 -0.748408311793373 0.454538540499814 -51.0395794683285 70.5852836310235 -0.723090945346796 0.469935929738403 SDS other 1 1 1 -0.748408311793373 -0.723090945346796 6.30792393651591e-06 78.4731186996897 15.9762855128919 4.91185004401473 1.19517130867481e-06 73.7175250201306 35.9131071779541 2.05266352072659 0.0405830488019844 MSI1 other 0.0389703540797953 1 0.011452131479722 4.91185004401473 2.05266352072659 9.43119844848989e-05 0.975669516774117 1.88988968151961 0.516257391272494 0.605885203126768 -16.5243157230588 4.17841353730669 -3.9546865276791 8.68057425463929e-05 HNF1A other 0.514188939411669 0.983161840080446 1 0.516257391272494 -3.9546865276791 3.86221217614294e-19 202.695402802377 35.9474549248049 5.63865795857805 2.76352865118542e-08 -457.419589913025 79.4958854992457 -5.75400333036564 1.46027964870022e-08 FBXO21 other 4.48286967284911e-15 0.000198671046205665 0.000290557402385635 5.63865795857805 -5.75400333036564 1.62740094141745e-08 -480.893477421451 189.766934799084 -2.53412681155754 0.0115542809797338 -2537.61747695029 419.478494867462 -6.04945785779096 2.71729920046374e-09 TBX3 other 0.000124268335886636 3.7694374508833e-05 1 -2.53412681155754 -6.04945785779096 0.134518978298309 100.159135309756 50.5580972019112 1.98107011246401 0.0480883902334067 100.957475958552 111.780406991307 0.903176850719496 0.366833264408406 OASL other 1 1 1 1.98107011246401 0.903176850719496 0.00072473938414911 16.7135467298624 9.26148219526332 1.80462979655787 0.0716885875252012 76.5175143977293 20.3109847454714 3.76729712304027 0.000183137190185005 HRK other 1 1 1 1.80462979655787 3.76729712304027 9.28914470664637e-05 43.6259409279948 10.0843704057515 4.32609465664937 1.80784708109134e-05 38.6402086975315 22.1630674811999 1.74345039242914 0.0818230378283389 RNFT2 other 0.507094409535826 1 0.159434034081445 4.32609465664937 1.74345039242914 9.68551721879843e-13 22.7443283507107 36.8967413263705 0.616431899758451 0.537868319536081 -576.409180912067 81.5761072977796 -7.06590691816151 4.92677834914763e-12 P2RX4 other 9.15475087520828e-09 7.18275015522233e-08 1 0.616431899758451 -7.06590691816151 1.32677589340591e-08 102.407404689947 31.9610819562645 3.20412822163158 0.00143408917614585 -289.968808816664 71.9525916222439 -4.02999811791381 6.37282153587065e-05 BICDL1 other 0.000101723907747431 0.729178240134319 1 3.20412822163158 -4.02999811791381 0.621854349367529 11.3592811849563 11.8090954158877 0.961909509992928 0.33652478881004 11.6870059772577 26.310253536906 0.444199671465123 0.657075854831177 DTX1 other 1 1 1 0.961909509992928 0.444199671465123 1.4495500926558e-16 256.201336625003 42.4951969209787 6.0289480973913 3.06755577131883e-09 -409.50772027825 94.5144035389329 -4.33275463786388 1.75746524467811e-05 TRAFD1 other 1.57116734542962e-12 0.209015341549567 3.3482371243945e-05 6.0289480973913 -4.33275463786388 5.9379433918162e-07 75.4552582090884 29.040843566476 2.59824608869806 0.00962505193315754 -370.935482292238 94.183135370646 -3.93844907405628 9.27173003621218e-05 DMTF1 other 0.00404255186114847 1 1 2.59824608869806 -3.93844907405628 5.27615470420562e-07 17.9819725304014 8.55502092990929 2.10192034335467 0.036021108714662 -119.874938242956 27.7450168586177 -4.32059345481071 1.85138233224325e-05 TMEM243 other 0.00360414127844286 0.219925707247176 1 2.10192034335467 -4.32059345481071 0.00098536710485667 -2.9704132692628 6.89626669036905 -0.430727725975435 0.666838543675083 -86.0829837622654 23.1698473611806 -3.71530215198963 0.000224138144370932 CCDC146 other 1 1 1 -0.430727725975435 -3.71530215198963 1.32427839460148e-13 43.3690330881612 9.3729995970242 4.62701749202361 4.64595509363119e-06 -162.304485181984 31.5050460190882 -5.15169808301968 3.62023256613602e-07 TMEM60 other 1.29726311535161e-09 0.00468240880104033 0.0428403519183732 4.62701749202361 -5.15169808301968 0.0358943758510228 1402.54141503491 608.133416753428 2.30630545271216 0.0214706326225917 3354.87542919882 1932.90858602555 1.73566171388225 0.0831930533890747 CD36 other 1 1 1 2.30630545271216 1.73566171388225 0.110783178753267 -70.0882459786527 54.6917160977177 -1.28151484318806 0.200609245486776 187.617678508596 167.908669418139 1.11737934175022 0.264370934405634 UGT2B28 other 1 1 1 -1.28151484318806 1.11737934175022 1.58963014917064e-10 51.7318213748996 22.7423284041589 2.27469327043221 0.0233163529746914 -376.099525602549 68.6393139374364 -5.47936020959297 6.56153660490271e-08 PNPLA8 other 1.35929274055581e-06 0.000873274906746502 1 2.27469327043221 -5.47936020959297 3.97267456299796e-09 238.720344796047 40.6710574399948 5.86953867988925 7.62573110898791e-09 -79.5498597646477 146.609714813669 -0.542596101941472 0.587631368942451 HILPDA other 3.14953639354478e-05 1 8.2029989539383e-05 5.86953867988925 -0.542596101941472 2.53874040760365e-18 100.155333583836 13.7280469970821 7.29567240009623 1.06425054535194e-12 -142.254870272775 42.1109486771638 -3.37809702088041 0.000782437619446064 RINT1 essential 2.88908658385295e-14 1 1.29242586227539e-08 7.29567240009623 -3.37809702088041 4.65880840305265e-11 219.03597705546 51.1752417873139 4.28011611485455 2.2083394282227e-05 -621.175015326941 155.589056863233 -3.99240812850334 7.44035208224209e-05 SRPK2 other 4.08624085031748e-07 0.846786470479972 0.193605117672284 4.28011611485455 -3.99240812850334 9.5580017589991e-21 73.2367856810707 8.83365876689931 8.29065142922398 9.05487809287545e-16 -98.7849728130718 32.4521581102689 -3.04401859738915 0.00244856382727696 KCP other 1.14925413150205e-16 1 1.17324055449387e-11 8.29065142922398 -3.04401859738915 0.00130951716769482 207.426538380529 70.99893292533 2.92154444910716 0.00362901529143401 -251.401396515334 218.296591143428 -1.15165058326612 0.249975261553366 TES other 1 1 1 2.92154444910716 -1.15165058326612 0.0342538509847942 37.2056972624854 32.6856353547325 1.13828894126418 0.255505542219556 -186.095490611113 100.501604178975 -1.85166686772195 0.0646203628628755 MDFIC other 1 1 1 1.13828894126418 -1.85166686772195 1.12481544066492e-36 74.0796932101024 10.4830805389874 7.06659582883052 4.97315269334828e-12 -162.814650110718 23.9951304458357 -6.78532048318054 3.08008974925816e-11 MTO1 other 1.62018416073375e-32 4.44025738253057e-07 5.94888525178322e-08 7.06659582883052 -6.78532048318054 7.87267867894238e-06 0.713276762157346 10.7643280066582 0.0662630088674513 0.947193003419367 -100.789129876946 24.6330879543059 -4.0916157188213 4.93910651722617e-05 ANKRD6 other 0.0483067563739905 0.570219847413761 1 0.0662630088674513 -4.0916157188213 0.00030645108537172 9.77862448702663 3.76580542166209 2.5966887271384 0.00967063906700452 -12.2621872241221 8.64818745802745 -1.41789100706184 0.156802589428471 KHDC1 other 1 1 1 2.5966887271384 -1.41789100706184 1.73031684600121e-23 20.1782047864827 7.87694617030691 2.56167864426278 0.0106891543831713 -128.834221812983 17.2899538727732 -7.45139187536294 3.72519905279745e-13 CEP162 other 2.18487108144573e-19 5.49802128202376e-09 1 2.56167864426278 -7.45139187536294 5.13205231224914e-43 1228.75733761405 125.993401393302 9.75255310219262 8.48079790392923e-21 -1277.72127681499 277.222966170975 -4.60900225714692 5.06071688617403e-06 SYNCRIP other 7.6113467842967e-39 0.0621759676635341 1.17518416554747e-16 9.75255310219262 -4.60900225714692 4.32815142386582e-34 146.11658753743 41.8754099749128 3.48931718220709 0.000524022962634946 -818.34321594881 92.0451477752902 -8.89067197704577 9.21820964108552e-18 SNX14 other 6.13342338276025e-30 1.40835806896505e-13 1 3.48931718220709 -8.89067197704577 0.00134588516029232 77.7835443815083 24.5545129228692 3.1677901584056 0.00162321095025748 9.8085735528661 53.9765905586525 0.181719027662702 0.85587167638834 NT5E other 1 1 1 3.1677901584056 0.181719027662702 0.204208664921844 -0.0221549077671306 9.0397796953762 -0.00245082386006185 0.998045437598629 -29.9334306324036 19.8351667791183 -1.5091090972785 0.131859026123563 MRAP2 other 1 1 1 -0.00245082386006185 -1.5091090972785 0.00136379890600161 47.9632635499061 15.7986017648223 3.03591825807666 0.00251503613337962 -4.33892980472278 36.113531461734 -0.120146926348655 0.904411949328424 EPHA7 other 1 1 1 3.03591825807666 -0.120146926348655 9.20673792260206e-47 165.618929626274 16.0296248216114 10.3320527753702 5.79735736313314e-23 -162.476060614323 35.2421452211289 -4.61027725738197 5.02082724442002e-06 AKIRIN2 essential 1.3806424188734e-42 0.0616909043521888 8.18354965379874e-19 10.3320527753702 -4.61027725738197 6.94349368077016e-42 187.357656692391 21.9189372181787 8.54775278689167 1.28741542701535e-16 -268.977409757995 48.2607681620747 -5.57341749834326 3.94529770508774e-08 ORC3 essential 1.02520684196571e-37 0.000529380046068673 1.69346625269599e-12 8.54775278689167 -5.57341749834326 1.27951516372326e-05 -25.6416953375809 8.82631465265925 -2.90514176603204 0.00382301829678078 -90.2606396170644 18.8822481027153 -4.78018502490096 2.26748635110352e-06 LCA5 other 0.0770577216549515 0.0283299744706874 1 -2.90514176603204 -4.78018502490096 6.22089700599321e-23 212.275099327317 39.3006189159152 5.40131695588525 9.93178839824483e-08 -444.242472708927 90.2847688438659 -4.92045865983418 1.14826336678001e-06 MAP3K7 other 7.7873188721023e-19 0.0145393107501685 0.00101433354911274 5.40131695588525 -4.92045865983418 0.142982330270523 -72.1396904316379 293.00750691032 -0.246204239585293 0.805617517057098 962.738674754796 642.753461129008 1.49783506892943 0.134759322597255 CGA other 1 1 1 -0.246204239585293 1.49783506892943 0.0374184117079318 -19.8301208387756 9.48022131976624 -2.09173606500408 0.0369410920118558 -53.3377085845138 25.302899626682 -2.10796823176222 0.0355061975621298 PRR5L other 1 1 1 -2.09173606500408 -2.10796823176222 0.0102566804540638 28.1102185274548 9.36456615551941 3.00176410317597 0.00280835067462328 43.0458271146409 40.6556911913326 1.05878970085787 0.29016894080325 LMO2 other 1 1 1 3.00176410317597 1.05878970085787 2.20932907222152e-11 70.1049928537396 20.7754444387438 3.37441603525949 0.000794301277401124 -289.032424964267 59.13313678209 -4.88782501137007 1.35603054863901e-06 PHF21A other 1.96939593497826e-07 0.0171185296460188 1 3.37441603525949 -4.88782501137007 1.82107697426702e-50 578.298057088818 36.8383703766777 15.6982529676432 5.37803018997755e-46 -348.456687403013 132.357976671105 -2.6326836974011 0.00871476812262592 NAT10 essential 2.75729264673769e-46 1 8.20526066084874e-42 15.6982529676432 -2.6326836974011 0.0170925451648587 230.309457360786 135.515620599689 1.69950487140605 0.0898086594848948 -771.035075009435 418.920638809618 -1.84052778397447 0.0662475412134245 EHF other 1 1 1 1.69950487140605 -1.84052778397447 2.86715357291179e-11 862.376912851687 127.355108477667 6.77143558008833 3.38251617100027e-11 1481.08693218542 393.693975373751 3.76202590039473 0.000187262393057876 ELF5 other 2.5420183577436e-07 1 3.94908762964282e-07 6.77143558008833 3.76202590039473 2.98068162115874e-11 106.111742741932 20.9331112159885 5.06908608314686 5.50676595422891e-07 -369.915916254826 93.7588248776609 -3.94539838503204 9.02233568933753e-05 PRRG4 other 2.64028778002241e-07 1 0.00538506642664045 5.06908608314686 -3.94539838503204 6.81819845100193e-21 1268.9478047431 155.658626769015 8.15212000184304 2.51007905686337e-15 -2873.06233495162 680.143769777068 -4.22419856303812 2.8144923355898e-05 CAPRIN1 other 8.22615643113383e-17 0.329999226347904 3.22720864340923e-11 8.15212000184304 -4.22419856303812 1.89350774120083e-24 744.512413662173 138.895865627466 5.36022012101526 1.23698557302491e-07 -3377.96933530348 430.323058111832 -7.84984506785508 2.28015708754862e-14 ATP5G2 other 2.42709822267122e-20 3.40404651600133e-10 0.00125603515084949 5.36022012101526 -7.84984506785508 1.61327835868104e-30 234.351992336573 29.0931020584931 8.05524250612386 5.01070857263127e-15 -596.820657703933 85.3174270877566 -6.99529601484641 7.77532161720581e-12 DNAJC14 other 2.21777375967883e-26 1.13084277600641e-07 6.40969840610992e-11 8.05524250612386 -6.99529601484641 6.15985269790431e-13 1133.01719377328 341.644356414539 3.31636443717079 0.000972598536882106 -5704.24977178912 991.809098597523 -5.75135858287171 1.47526137729686e-08 CD63 other 5.86233181259553e-09 0.000200635547312373 1 3.31636443717079 -5.75135858287171 0.0705063018699646 5.23137149147639 4.56126569602365 1.14691224763269 0.251925805997095 31.5194076365853 14.1164213287352 2.23281856658846 0.0259699842498468 PRPH other 1 1 1 1.14691224763269 2.23281856658846 0.00466459353972843 4.3875442374207 6.57379049605842 0.667429885398907 0.504791399767419 -56.2664566851613 18.9126918094238 -2.97506337289993 0.00306440124103326 AVIL other 1 1 1 0.667429885398907 -2.97506337289993 0.691425278996146 -346.745715450836 492.360132759404 -0.704252217797408 0.48157874502771 -957.324807759028 1448.57904876959 -0.660871637327748 0.508975953586749 LACRT other 1 1 1 -0.704252217797408 -0.660871637327748 6.7994333997279e-09 65.3673541267807 10.6331142113544 6.14752675721093 1.52018008744519e-09 20.9197101519523 30.868413961013 0.677706025919377 0.498245175787407 GDF11 other 5.31987669194711e-05 1 1.67812679853075e-05 6.14752675721093 0.677706025919377 2.90084386135953e-08 17.462590444192 7.98696379742937 2.18638657781476 0.0292166285347775 -113.774140810521 23.618640356955 -4.81713337817169 1.89548234684866e-06 GLS2 other 0.000218375525883146 0.0237636621824416 1 2.18638657781476 -4.81713337817169 0.192075194679355 87.7784225370394 67.1969464680622 1.30628588277831 0.192006374279725 308.230719356828 195.060185781933 1.58018264014889 0.114645213860112 ITGA7 other 1 1 1 1.30628588277831 1.58018264014889 0.0466936585825839 -8.05526441396411 3.78302003013664 -2.12932111112115 0.0336785992954032 7.42858377512 11.1302460392536 0.667423141314328 0.504786473390317 TESPA1 other 1 1 1 -2.12932111112115 0.667423141314328 0.00266230530598366 2.1869364812681 0.707807361800193 3.08973401421819 0.00210615097756269 -1.38502779030914 2.05862796950214 -0.672791689818581 0.501366561779765 FAM186B other 1 1 1 3.08973401421819 -0.672791689818581 0.166956916731026 42.559461664607 22.4688363855997 1.89415512820608 0.0587326491252821 30.3428576044723 65.22805351158 0.465181098790346 0.641987243591805 RDH5 other 1 1 1 1.89415512820608 0.465181098790346 0.223005920061949 12.5308421966179 11.0994718520681 1.12895841924974 0.259437934025936 -31.6261475561742 31.7322767869557 -0.996655480112756 0.319397102078082 AGAP2 other 1 1 1 1.12895841924974 -0.996655480112756 4.4627190964178e-09 140.593099015508 40.5479271144697 3.46733135379777 0.000567072853429608 -482.755889867715 117.714102564344 -4.10108796950507 4.7385134966741e-05 BLOC1S1 other 3.52867198953755e-05 0.547772160215526 1 3.46733135379777 -4.10108796950507 0.00078491986775954 1.62794693943391 3.70728886596914 0.439120607616408 0.660747554297882 42.4233050887663 11.2739967283921 3.76293395419646 0.000186071367666021 KRT85 other 1 1 1 0.439120607616408 3.76293395419646 4.97595629120368e-06 371.902328147197 76.5565844375454 4.8578751374494 1.57432633226892e-06 514.913453019693 218.867596549964 2.35262533667082 0.0190145376575958 CDK4 essential 0.0310698710822757 1 0.0149718434198774 4.8578751374494 2.35262533667082 0.0319954833284605 152.252171016688 82.5740064741576 1.84382685929545 0.0657550384072005 555.212752434886 241.547415218677 2.29856631639896 0.0219099507025751 PPP1R1A other 1 1 1 1.84382685929545 2.29856631639896 1.13348723403343e-09 98.231310627007 18.823430773683 5.21856572311695 2.57541287911579e-07 300.898012034638 57.99408421468 5.18842595946144 3.00568425346369e-07 TROAP other 9.2492558297128e-06 0.00389807190831705 0.00257000451206965 5.21856572311695 5.18842595946144 2.83881974650919e-12 305.535881047409 52.8738166059841 5.77858570952545 1.30167026673047e-08 -480.017493027648 151.160938618102 -3.17553924589196 0.00158462058558857 TSPAN31 other 2.63697966253239e-08 1 0.000138745033730801 5.77858570952545 -3.17553924589196 0.00785293679652118 44.5896037273144 30.2676363421417 1.47317759547785 0.141314065907733 261.944970743806 86.3011080706071 3.03524458260138 0.00252494412173203 B4GALNT1 other 1 1 1 1.47317759547785 3.03524458260138 9.6413895672192e-11 56.8677480966901 22.7438334346011 2.50035897687217 0.0127010002189903 -370.189014211585 67.1440903787729 -5.51335213751913 5.45457979831313e-08 TFCP2 other 8.31733975450472e-07 0.000728240948872785 1 2.50035897687217 -5.51335213751913 0.0305180094337772 24.5283931475228 9.49925206864305 2.58213941163755 0.0100831702891541 2.61523738971795 28.0261607233066 0.0933141508584554 0.925688859023649 COQ10A other 1 1 1 2.58213941163755 0.0933141508584554 0.145926102235845 55.0692206593011 63.9504253017882 0.861123603157042 0.389551456883086 -273.898635799885 187.119485945621 -1.46376329763691 0.143839409909605 FAIM2 other 1 1 1 0.861123603157042 -1.46376329763691 9.17588739006833e-15 117.528291250348 23.3196298135776 5.03988666157637 6.36900969243835e-07 -347.754878115207 68.9604824192225 -5.04281388290102 6.27664364215879e-07 PAN2 other 9.38785038877891e-11 0.00804100816996963 0.00620086783655798 5.03988666157637 -5.04281388290102 4.23507939684913e-08 126.264117996078 23.9770922677631 5.26603128461238 2.02015008088425e-07 280.939963269197 69.1568447985559 4.06235946835828 5.5827598696853e-05 ESPL1 essential 0.000314706455945903 0.641682419421628 0.00202823068120779 5.26603128461238 4.06235946835828 0.137698395214517 -71.7309322437726 689.792678932195 -0.103989117940209 0.917216169822273 3977.05851757201 2109.59712465348 1.88522181372677 0.0599306321504544 KRT7 other 1 1 1 -0.103989117940209 1.88522181372677 4.54700871002595e-19 29.8605306857931 6.7028726519549 4.45488557463258 1.02083653522763e-05 -136.637503680412 19.6494956923805 -6.95374099261978 1.03127409733659e-11 ZC3H10 other 5.26770959056506e-15 1.49710060710353e-07 0.0919365383626005 4.45488557463258 -6.95374099261978 0.0379835205187127 209.200068460879 113.082861703384 1.84997147498452 0.0648637725303068 -438.565824258123 356.602433139971 -1.22984529408968 0.21929058170868 HNRNPA1 other 1 1 1 1.84997147498452 -1.22984529408968 0.0597855511318568 14.7723711009028 12.263334672037 1.20459658779328 0.228912358493162 79.8731410147346 34.9660395966883 2.28430619927284 0.022759569080135 SLC26A10 other 1 1 1 1.20459658779328 2.28430619927284 1.70595805879178e-22 180.534162259057 38.4377300492826 4.6967956231439 3.35342693486893e-06 -874.785219539589 114.367928619221 -7.64886826316594 9.31235709414416e-14 ACVR1B other 2.12101765449582e-18 1.38390938776076e-09 0.0312069910558902 4.6967956231439 -7.64886826316594 7.61732068508496e-11 650.62596907332 169.456637968403 3.83948352141056 0.000138672348331058 -2301.4145228534 486.791259539133 -4.72772359354244 2.93614316010361e-06 OS9 other 6.61107262258524e-07 0.0364962594800878 1 3.83948352141056 -4.72772359354244 9.17451878801923e-14 4.20278162753691 0.735434066733713 5.71469533115693 1.8203185302906e-08 -8.44589309534934 2.17478796310896 -3.88354783942962 0.00011572918147427 MIP other 9.03414865056253e-10 1 0.000192844545098986 5.71469533115693 -3.88354783942962 0.352488067872257 12.1616754687821 8.67195239610726 1.40241492495293 0.161364929840461 1.03157823238469 25.2197237957723 0.040903629268042 0.967387814738131 KCNH3 other 1 1 1 1.40241492495293 0.040903629268042 1.93999765963711e-30 184.563303128247 18.7701010251932 9.83283483027215 4.35184793489427e-21 -83.9619260705243 40.9588412795181 -2.04990970075392 0.0408592404665335 LTV1 essential 2.66400478621368e-26 1 6.04428159677466e-17 9.83283483027215 -2.04990970075392 2.89720215115562e-14 295.780007570099 65.7581212724368 4.49799966675871 8.43785211971848e-06 -599.209878453945 152.323628823017 -3.93379466523976 9.47597235640271e-05 MAP7 other 2.90821151933001e-10 1 0.0764975673173677 4.49799966675871 -3.93379466523976 7.95985357600059e-22 1549.97298187658 299.853119449226 5.16910741073358 3.33814828721233e-07 -3865.91391303558 740.335626633915 -5.22183962780872 2.54901373842933e-07 CD164 other 9.77549617668632e-18 0.00331524726820118 0.00331144310091463 5.16910741073358 -5.22183962780872 2.41033385274971e-45 29.1148213248749 2.23264745566452 13.0404920181226 6.56957004613752e-34 -15.104003825733 6.39952988080794 -2.3601739670018 0.0186277239173496 AFG1L other 3.60320807647554e-41 1 9.78734545473567e-30 13.0404920181226 -2.3601739670018 1.40362317893053e-12 155.889665786258 22.9307214939431 6.79828874235095 2.88099109379839e-11 8.42137943876621 51.8347310481957 0.162465961884437 0.87100132338963 NHSL1 other 1.31898470124102e-08 1 3.37133577796287e-07 6.79828874235095 0.162465961884437 3.90363610227229e-13 45.6200686530663 15.3247699788635 2.97688439800318 0.00304502182143777 -171.979129610289 34.8412091615954 -4.93608384291833 1.06932892951724e-06 AHI1 other 3.74631956735072e-09 0.0135601601552081 1 2.97688439800318 -4.93608384291833 0.00049380127410715 80.2370856557145 23.4683961563247 3.41894201551948 0.000676576908739872 -5.91330298306978 53.5637040489131 -0.110397574030166 0.912135476768436 HEY2 other 1 1 1 3.41894201551948 -0.110397574030166 0.00175444895806245 -52.3535165115245 116.267866808137 -0.450283624777578 0.652689380189666 -890.057426627802 266.264025381595 -3.34276260321769 0.000887848385825789 PKIB other 1 1 1 -0.450283624777578 -3.34276260321769 2.22700218446269e-41 85.9838088489776 7.68643191963405 11.1864399175048 3.65056312733888e-26 -103.465232368927 23.4672994899153 -4.40891089379029 1.26434506764558e-05 SMPD2 other 3.2797061170582e-37 0.151734051568147 5.2633819169972e-22 11.1864399175048 -4.40891089379029 7.0103822097318e-14 103.797882952005 19.2530536829682 5.39124258734227 1.0666280236444e-07 -183.611009603381 58.5984298038833 -3.13337763857988 0.00182629563989688 MICAL1 other 6.94027838763448e-10 1 0.00108700061889601 5.39124258734227 -3.13337763857988 2.07205732535242e-35 275.581187779048 27.0914793163641 10.1722458401372 2.65443117847725e-22 -206.664002939574 61.286521190815 -3.37209551013881 0.000801093970039393 REPS1 other 2.96552844404439e-31 1 3.72416694340359e-18 10.1722458401372 -3.37209551013881 0.630803430608833 -1.96578252556029 5.91998688227091 -0.332058594833611 0.739974340088738 8.27822929625155 12.8963497714994 0.641904836866805 0.521208373333035 STX11 other 1 1 1 -0.332058594833611 0.641904836866805 0.00894346684972844 0.876166192006044 2.20227360543196 0.397846203053499 0.690901958596382 -12.7704970666909 4.91857088459353 -2.59638365824756 0.00967960587501021 TEC other 1 1 1 0.397846203053499 -2.59638365824756 0.000746423928094212 51.9207191595368 13.97730796452 3.71464371331964 0.000224426849973334 -13.6817469692885 47.0572380830051 -0.290746918575098 0.771355288616566 PRADC1 other 1 1 1 3.71464371331964 -0.290746918575098 0.000245173644673315 42.6381700489418 10.7803172942821 3.95518692864052 8.65710096451575e-05 -18.6498806017178 36.7626386622259 -0.507305277324415 0.61214584846944 SEMA4F other 1 1 0.71957823217055 3.95518692864052 -0.507305277324415 1.12176967591694e-21 1162.78018159501 118.45833068837 9.81594265965101 4.70028884955482e-21 -572.289506925356 398.812266587229 -1.43498471554707 0.151864001719673 CCT7 essential 1.37315826028993e-17 1 6.52729112537678e-17 9.81594265965101 -1.43498471554707 0.000477806127690857 -29.4844940250552 33.7577444288412 -0.873414220171205 0.382821308706329 -446.644267654692 113.65180053023 -3.92993569455939 9.58831488412406e-05 RAB11FIP5 other 1 1 1 -0.873414220171205 -3.92993569455939 3.45089442965504e-16 136.642974475613 16.4935779250707 8.28461690340165 9.2084250150679e-16 -76.4567545885706 55.5287345196092 -1.37688631390602 0.169111670943257 SMYD5 other 3.701429365248e-12 1 1.19295146070205e-11 8.28461690340165 -1.37688631390602 2.70765033091259e-05 90.9792142009669 30.3379356623461 2.99885975148552 0.00283388098589997 405.880841775423 102.731311909065 3.95089709488669 8.81130284515939e-05 DYSF other 0.157801861285586 0.99726325601514 1 2.99885975148552 3.95089709488669 0.00235251806635254 82.7132826780837 29.0772853731144 2.84460126235039 0.00461537399180226 -158.44115063781 99.4874111413524 -1.59257486771563 0.111840753449722 CCDC142 other 1 1 1 2.84460126235039 -1.59257486771563 0.081641197036483 -13.833938048305 9.10952676332634 -1.51862313023751 0.129436187381878 -57.3934654260873 30.6689364513887 -1.87138753627984 0.0618259002502148 EMX1 other 1 1 1 -1.51862313023751 -1.87138753627984 4.98766499278964e-37 68.2365871439267 4.89760551288099 13.9326425871705 7.71868531278743e-38 -0.753280423112128 35.4716998548068 -0.0212360959918883 0.983065282633509 KCNMB4 other 7.20019318359113e-33 1 1.16104464474948e-33 13.9326425871705 -0.0212360959918883 1.17693819426592e-14 899.13519695769 133.002619946802 6.76028184495406 3.68895966708444e-11 -2015.98506375647 557.581124427769 -3.61559058482373 0.000328673421212866 GNS other 1.19906463231812e-10 1 4.30243365972058e-07 6.76028184495406 -3.61559058482373 0.107140583680994 58.9008068791272 38.1627152405265 1.54341237272808 0.123339072743603 302.499960410763 187.058794220035 1.61713840652119 0.106454836157392 CPM other 1 1 1 1.54341237272808 1.61713840652119 3.43933198498376e-29 793.472675974198 68.0917656640968 11.6529901704778 4.83274803590948e-28 -766.120454466114 333.502577319625 -2.297195004079 0.022004033826243 MDM2 og 4.67233250160044e-25 1 7.04179716312371e-24 11.6529901704778 -2.297195004079 3.24431279761341e-19 193.845752166426 30.6051554890748 6.33376138982935 4.99042135583061e-10 -118.156370191695 64.7624196918205 -1.82445885675606 0.0686270832790932 KLHL36 other 3.77346021490415e-15 1 5.62071157307202e-06 6.33376138982935 -1.82445885675606 4.25983608121073e-15 148.826847833345 36.745483341725 4.05020792485671 5.85715078159763e-05 -270.547837795731 78.4576150021452 -3.44833115037124 0.00060749957230987 MPHOSPH6 other 4.41148624570183e-11 1 0.49434352596684 4.05020792485671 -3.44833115037124 0.000157625372207344 70.7692329884569 25.5543246929645 2.76936424025092 0.00580690313854591 -44.8017302841261 54.8943560265827 -0.816144564341564 0.414772072366105 KIAA0513 other 0.835414472698923 1 1 2.76936424025092 -0.816144564341564 6.09805458982897e-46 724.290263984229 80.1593190315227 9.03563394418809 2.93665277549624e-18 -915.210667328569 174.474893459624 -5.24551498029923 2.24610353656024e-07 DYNC1LI2 other 9.13000733189193e-42 0.00292599907707702 3.95890160664648e-14 9.03563394418809 -5.24551498029923 3.72370529369475e-05 10.031518753088 8.94437397697594 1.12154509403458 0.262587862252868 -57.339439452692 19.6838370038085 -2.91302145214867 0.00373773499689859 FBXL8 other 0.2139641061757 1 1 1.12154509403458 -2.91302145214867 2.88805242077866e-19 118.210753859482 29.9389313577297 3.94839590121048 8.94034710162819e-05 -314.083400772862 65.8523348754254 -4.76951047167912 2.39601265201191e-06 FHOD1 other 3.36486987544922e-15 0.0299166139730207 0.741780599022091 3.94839590121048 -4.76951047167912 3.81176206098831e-10 12.7831284830348 8.24126110338049 1.55111315157716 0.12145504715001 -77.6221116751673 17.9774811621113 -4.31774123277965 1.87290393308866e-05 CCDC102A other 3.19235072607771e-06 0.222388613014948 1 1.55111315157716 -4.31774123277965 2.76275916160641e-17 17.9889300738326 4.37660976372284 4.11024309796604 4.58427563165798e-05 -39.5124988236438 9.6229868993715 -4.10605347766029 4.66553087615529e-05 SLC9A5 other 3.06086087514374e-13 0.539475335209836 0.390763654842526 4.11024309796604 -4.10605347766029 0.50296545574705 2.71446970402338 81.9232624326547 0.0331342969434941 0.973579668505172 -571.927124749996 489.908725258877 -1.16741567410905 0.243554919046585 AGT other 1 1 1 0.0331342969434941 -1.16741567410905 4.28821337514772e-07 9.04172143669393 1.66068787789071 5.44456400089949 7.90093475816632e-08 10.7683123669385 10.5502297152195 1.02067089130812 0.307868281123617 ZNF670-ZNF695 other 0.00295629430082684 1 0.000812058074444335 5.44456400089949 1.02067089130812 3.56618616669056e-07 65.5810154699411 12.0490025121654 5.44285847759819 7.93754268739865e-08 -47.9720352846502 71.9367980841767 -0.666863643673935 0.505141455359617 PCNX2 other 0.00247600305553325 1 0.000815661886557085 5.44285847759819 -0.666863643673935 8.71322581689334e-08 162.183580703794 29.8872654520639 5.42651119969206 8.65235416436189e-08 410.767571436416 180.736303081081 2.27274523398954 0.0234293376976443 KCNK1 other 0.000632667326564625 1 0.000887385443096956 5.42651119969206 2.27274523398954 3.73487384037113e-15 101.519435487298 12.0771468687036 8.40591214058781 3.73308713332148e-16 45.3878845371289 71.5210621949314 0.634608647357945 0.52595047599969 URB2 essential 3.87567858415312e-11 1 4.87242532641119e-12 8.40591214058781 0.634608647357945 5.89878244351812e-13 210.445186366091 27.4801761602103 7.65807268261995 8.6837865274315e-14 190.213899192384 165.740620748138 1.14766011092378 0.251613356749679 EGLN1 other 5.6162307644736e-09 1 1.08295501783598e-09 7.65807268261995 1.14766011092378 0.032930473663866 43.8223227697953 19.8595049711654 2.20661707496849 0.0277585785159699 -149.131558494958 118.761685945967 -1.25572113015311 0.209757153960177 CAPN9 other 1 1 1 2.20661707496849 -1.25572113015311 8.98952167230353e-19 198.365239052645 22.7746263765615 8.70992286647532 3.65644614687772e-17 -423.429081004596 136.190302141747 -3.10909862409947 0.00197478643002733 COG2 other 1.03352530666474e-14 1 4.8561261276683e-13 8.70992286647532 -3.10909862409947 4.87760880639173e-17 90.3376007152642 10.0722145897976 8.96899087185551 4.83778007272002e-18 19.1141378653389 60.2094330040554 0.317460851425914 0.751015973730149 ABCB10 other 5.36683296967282e-13 1 6.50584664179388e-14 8.96899087185551 0.317460851425914 2.70662107317628e-28 192.776718792019 16.4244523157424 11.7371779031711 1.61358457789121e-28 -161.387342210502 98.3188928380369 -1.64146826262943 0.10127714748171 NTPCR other 3.64284130238795e-24 1 2.35664027601012e-24 11.7371779031711 -1.64146826262943 4.12422196427278e-23 144.498241842645 13.5739222215231 10.6452828802515 3.65504979240649e-24 27.8268914067806 81.1418534933619 0.34294128379822 0.731775354531272 TAF5L other 5.17713583175162e-19 1 5.20734943924153e-20 10.6452828802515 0.34294128379822 2.00351673693522e-08 4905.88938968842 848.545563965067 5.78152735459988 1.24977811644204e-08 -9034.06106771532 5931.1793702252 -1.52314750639084 0.128303951188924 GLUL other 0.000152287307174446 1 0.000133276338337379 5.78152735459988 -1.52314750639084 2.18781738780613e-29 312.317428952594 25.5495453574036 12.2239916438315 1.61166856166461e-30 77.6175156174823 179.721799385556 0.431875909783043 0.666003353665677 STX6 other 2.97674433784902e-25 1 2.37398779133198e-26 12.2239916438315 0.431875909783043 1.57733871770479e-07 47.1515079453392 8.69513314398926 5.42274708903497 8.85279658876508e-08 -91.3209481556745 61.6774910430268 -1.48062034643997 0.139288820922043 RNASEL other 0.00112590437669768 1 0.000907234594416645 5.42274708903497 -1.48062034643997 4.18882623541755e-06 321.857910435412 63.9545274770171 5.03260555792671 6.58981692766419e-07 131.402707078059 450.733046956182 0.291531113517029 0.770756485840279 DHX9 essential 0.026343528194541 1 0.00641123288892449 5.03260555792671 0.291531113517029 0.254136680266703 4.59219853788023 4.11040383101589 1.11721347261037 0.264398966478893 36.6427356270398 28.7888074933263 1.27281186049593 0.203631517256591 KIAA1614 other 1 1 1 1.11721347261037 1.27281186049593 1.6804429007548e-09 274.947624318142 42.5418362614223 6.46299380752094 2.28685372404133e-10 14.8889079128259 299.518955487163 0.0497094011582983 0.960372243733105 CEP350 other 1.36048657245109e-05 1 2.60472639168308e-06 6.46299380752094 0.0497094011582983 0.078378360559441 12.5865445462622 9.57453978171906 1.31458480858725 0.189204444581005 127.910112236109 67.3349565022508 1.89960933934566 0.0580139869314603 NPL other 1 1 1 1.31458480858725 1.89960933934566 0.123895543967581 -168.376521983173 122.008335051888 -1.38004114154631 0.168142946867647 -1399.87846890564 870.10851152777 -1.60885504550194 0.108230321538896 FAM129A other 1 1 1 -1.38004114154631 -1.60885504550194 9.43657975385721e-22 145.506139425085 14.1654732424049 10.271886927823 1.0164260958301e-22 -9.07201350114932 103.396950697727 -0.0877396619526108 0.93011630384111 PIGC other 1.15701904362043e-17 1 1.43143287075752e-18 10.271886927823 -0.0877396619526108 0.0672589452249318 302.525965156101 131.384023355235 2.30260847118476 0.0216767394840151 -214.915582234042 921.44223095799 -0.233238259560344 0.815663971511169 LAMC1 other 1 1 1 2.30260847118476 -0.233238259560344 0.000211677951055436 59.5523687888365 14.5183769758926 4.10186130913405 4.73295218778927e-05 -36.7135054290568 109.555874275439 -0.335112157808663 0.737671103241466 RC3H1 other 1 1 0.402821560702745 4.10186130913405 -0.335112157808663 0.0100395539511413 5.11610175793045 5.5613137294598 0.919944820021402 0.358010088139302 34.4108602487908 11.2974044755694 3.04590849369023 0.00243242787477786 GPR55 other 1 1 1 0.919944820021402 3.04590849369023 1.01750714823757e-07 156.527977926851 44.613943854796 3.50849901179548 0.000488010245265635 -291.571197489391 91.021875893222 -3.20330903563703 0.00143824734294807 SP110 other 0.000735657668175764 1 1 3.50849901179548 -3.20330903563703 3.44558902800905e-22 99.1403210606812 13.8047373742328 7.18161587381819 2.2763067273622e-12 -156.888684760104 29.6178668239172 -5.29709602966452 1.71129321130627e-07 MRPL44 other 4.25943715642478e-18 0.0022405962015633 2.74545354387155e-08 7.18161587381819 -5.29709602966452 0.169807783675396 -6.91887774729309 39.2051627387609 -0.176478740654547 0.859983649195217 -152.951486135205 82.5237950455242 -1.85342283459977 0.0643639856961376 DOCK10 other 1 1 1 -0.176478740654547 -1.85342283459977 1.02536442516438e-05 148.215880412773 57.0823803050236 2.5965259265779 0.00967182707688886 603.159631222411 130.066674612152 4.63731107926747 4.42535386057052e-06 TTLL4 other 0.0623113961172394 0.0545159342083683 1 2.5965259265779 4.63731107926747 9.93234596187615e-06 108.283701772495 29.6965707977315 3.64633689559761 0.000291512019694616 -140.387012662093 67.5043228405435 -2.07967440831472 0.0380222494393708 USP37 other 0.0604283928320545 1 1 3.64633689559761 -2.07967440831472 3.08416628702559e-05 -11.9940146592296 3.81640487191822 -3.14275216119853 0.00176502593973815 -32.4606232691696 7.76385672492838 -4.18099205320782 3.38315064712586e-05 HTR2B other 0.178696594670263 0.394204713403105 1 -3.14275216119853 -4.18099205320782 5.58478506852183e-08 243.037200731972 103.121328594739 2.35680827665725 0.0187868756478288 1224.83413101869 209.483481038216 5.84692465939709 8.65031179464211e-09 ITM2C other 0.000412436377310337 0.000118517921898392 1 2.35680827665725 5.84692465939709 0.302892244412395 81.3501260331937 55.4736465477781 1.46646436814153 0.143103907701136 -7.41636359006479 115.368471197574 -0.0642841455128922 0.948767766751109 SLC19A3 other 1 1 1 1.46646436814153 -0.0642841455128922 0.000109438961825093 357.510053663019 119.984039779623 2.97964674568105 0.00301470853075716 979.161298110574 257.424043272389 3.80369015132938 0.000158712626212236 SERPINE2 other 0.591408149702801 1 1 2.97964674568105 3.80369015132938 7.43531239768457e-07 288.397453168834 85.624137953241 3.36817934828526 0.000810834581899485 -611.296335136171 193.186494773287 -3.16428089786273 0.00164254574403702 DNAJB2 other 0.005025527649595 1 1 3.36817934828526 -3.16428089786273 0.0116092033914113 7.96614213321798 7.13423203470379 1.11660821998324 0.26465938709684 48.1270070914452 16.1562123090367 2.9788545836654 0.0030235973528835 WNT10A other 1 1 1 1.11660821998324 2.9788545836654 0.138243195336311 136.38017516281 86.9887472395348 1.56779100160242 0.11751138051782 318.463060880974 198.21067414611 1.60668976205702 0.108702690352127 CYP27A1 other 1 1 1 1.56779100160242 1.60668976205702 6.75121248664095e-18 184.507661373268 32.4974893095937 5.67759741731184 2.22119297687965e-08 -328.548435369768 64.4245561990974 -5.09973921053369 4.69854730392168e-07 EIF4E2 other 7.60321550245503e-14 0.00605266863691191 0.000234335859060803 5.67759741731184 -5.09973921053369 4.62967574069285e-17 -28.2344221307115 17.7408336268637 -1.59149354109032 0.112081586173343 -320.913435877201 36.0942263747947 -8.89099083451477 8.98673680075719e-18 ARMC9 other 5.09634705535469e-13 1.37308351578769e-13 1 -1.59149354109032 -8.89099083451477 2.66844242771295e-10 135.475803745828 61.2085137935337 2.2133490155113 0.0272885461837389 -666.550509895954 124.340645270733 -5.36068080107387 1.22789468565607e-07 CAB39 other 2.25403331868913e-06 0.00161885635356897 1 2.2133490155113 -5.36068080107387 8.7725849246327e-15 535.78423950211 69.1092345591164 7.75271558019931 4.50106680243976e-14 -357.683659407464 273.733278243836 -1.30668679271377 0.191875318371258 COX5B essential 8.98312696282388e-11 1 5.6519895838236e-10 7.75271558019931 -1.30668679271377 3.37871594072765e-08 84.1571461477147 17.5594050428606 4.79271056976567 2.12688324597207e-06 -148.46974069232 55.9981791703034 -2.65133157706413 0.00825166225638991 REV1 other 0.000253032036801094 1 0.0200692703089924 4.79271056976567 -2.65133157706413 0.000296367836363269 5.10936055685568 4.9031872479281 1.04204883446267 0.297851058454769 -58.0571542873873 15.8156926450455 -3.67085752046241 0.000265530539993354 TSGA10 other 1 1 1 1.04204883446267 -3.67085752046241 2.69394557915759e-14 51.0061878854792 7.08811597956391 7.19601485536321 2.05452022658723e-12 -52.969080221582 22.565507396817 -2.34734718303093 0.0192631532467417 MFSD9 other 2.70633772882171e-10 1 2.48186043371737e-08 7.19601485536321 -2.34734718303093 5.82531949686046e-10 59.82491804813 59.6178590485396 1.00347310357827 0.316103893410793 -1406.80307721169 223.115022643044 -6.30528173561134 6.19264372422748e-10 TMEM127 other 4.83210252264575e-06 8.71924236371229e-06 1 1.00347310357827 -6.30528173561134 7.87287118387564e-10 53.5843539336702 20.1902735442361 2.65396869518726 0.00818699757202615 -342.460225902348 63.6947856690152 -5.37658180815483 1.12692355505393e-07 TGFBRAP1 other 6.47858569721127e-06 0.00148855332387074 1 2.65396869518726 -5.37658180815483 0.000343895467629753 20.2064033055829 31.0809985593875 0.650120788975743 0.515890166537379 -459.673354523439 121.189081997405 -3.79302612865143 0.000165599463558775 GCC2 other 1 1 1 0.650120788975743 -3.79302612865143 8.71675921995791e-18 146.85680192203 16.1546161736022 9.0907020224971 1.81276218923048e-18 26.4578496835925 50.963391480971 0.519154022421594 0.603863702887856 MRPS9 essential 9.78892060401273e-14 1 2.45031065118283e-14 9.0907020224971 0.519154022421594 7.54155905302226e-09 47.3401847141146 10.3872995103128 4.55750646904079 6.39251812092801e-06 -105.471351123381 32.7690862899733 -3.21862349746547 0.00136454682356521 C2orf49 other 5.88317021726266e-05 1 0.058427615625282 4.55750646904079 -3.21862349746547 0.778209207511259 2.48146776833252 8.56988176480175 0.289556826620924 0.772271608544028 25.2200930110268 36.3576639387031 0.693666486756313 0.488203522900979 ANKRD36 other 1 1 1 0.289556826620924 0.693666486756313 3.77877526463599e-09 6.72924712326527 23.1680642674863 0.290453576335637 0.771583088762168 -322.374412227012 54.7255983525117 -5.89074257627036 6.84425666680399e-09 EPC2 other 2.99996968259451e-05 9.40195538318864e-05 1 0.290453576335637 -5.89074257627036 3.69330416622097e-06 62.2781551378867 12.5597260445813 4.95855999699575 9.54528423866289e-07 81.0894129048586 35.3299119259136 2.29520563410693 0.0221067228615221 ARHGEF4 other 0.0233860019805112 1 0.00919497230710397 4.95855999699575 2.29520563410693 1.54511582908067e-21 83.6593804225611 31.5563664354404 2.65110942331449 0.00825529769848408 -624.700672358355 72.5944332265667 -8.60535229207822 8.08914063565257e-17 ISCU essential 1.88565935781005e-17 1.22938759380648e-12 1 2.65110942331449 -8.60535229207822 0.0758099115791608 -8.32420599801443 31.8236260397484 -0.261573146555245 0.793749371961392 160.237210546164 77.2149480621818 2.07520971738689 0.0384356348955186 ALDH1L2 other 1 1 1 -0.261573146555245 2.07520971738689 0.209392969164214 -0.0549947473911246 2.09534530989248 -0.0262461500409909 0.97907059578769 -8.59153469820712 5.08278673616898 -1.69031972895301 0.0915375689627234 STAB2 other 1 1 1 -0.0262461500409909 -1.69031972895301 3.25950414260741e-10 260.477508152955 47.2729274165438 5.51007780537402 5.56456630341295e-08 -247.938258837745 116.709725770892 -2.12440100600066 0.0340911642708072 SCYL2 other 2.74059108310431e-06 1 0.00057660036035965 5.51007780537402 -2.12440100600066 2.59569528568423e-10 820.372272097065 121.021947339108 6.778706591114 3.16401621409062e-11 557.806749457191 292.307363383924 1.90828839547416 0.0568800334549001 CKAP4 other 2.19569864216029e-06 1 3.69810215102912e-07 6.778706591114 1.90828839547416 0.0192161503741262 -65.8467492335298 39.9520071315157 -1.64814621244867 0.0999064988551822 -275.422623333913 103.873343696193 -2.65152361071059 0.0082492215788927 PLXNC1 other 1 1 1 -1.64814621244867 -2.65152361071059 1.56651505159498e-18 50.5676083800227 35.5606978706384 1.42200832402041 0.15559585861699 -728.403152919557 86.6458033533281 -8.40667550797864 3.69801924271615e-16 APPL2 other 1.79099665848854e-14 5.59695212385089e-12 1 1.42200832402041 -8.40667550797864 2.86328841884833e-29 205.860653776328 22.4868820531884 9.15469976181687 1.08579407366282e-18 -255.514028830055 52.0338590808349 -4.91053389742076 1.20167532132147e-06 PWP1 essential 3.89178161889864e-25 0.0152035961653593 1.47179386684996e-14 9.15469976181687 -4.91053389742076 0.035148085959318 80.5705810222901 31.0493389975298 2.59492097492639 0.0097160682974856 52.3833678009534 75.160359820994 0.69695472354992 0.486128298118684 DRAM1 other 1 1 1 2.59492097492639 0.69695472354992 1.6413790082708e-05 101.722316235575 34.1740831755353 2.97659239936528 0.00304416795185302 -215.944551858662 83.2672323074 -2.59339173255397 0.00975884199419546 WASHC4 other 0.0978918440532707 1 1 2.97659239936528 -2.59339173255397 0.856957948868024 11.1620505976049 22.2534458902342 0.501587513801774 0.61615988549626 -3.95107967702246 53.8924420245446 -0.0733141703844667 0.9415829652116 SLC41A2 other 1 1 1 0.501587513801774 -0.0733141703844667 2.82271191037382e-17 -32.1848694490163 10.7560421923909 -2.99225950152788 0.00289555454364572 -194.468857209908 21.5808333391945 -9.01118386641351 3.49680937640505e-18 VILL other 3.126153440739e-13 5.35081770777501e-14 1 -2.99225950152788 -9.01118386641351 2.438424880859e-21 1476.15680046107 773.488495511177 1.90844053793653 0.056860338334119 -11476.6392684454 1462.29611057623 -7.84836886690685 2.25134610458321e-14 FLNB other 2.96512465512455e-17 3.36125973414273e-10 1 1.90844053793653 -7.84836886690685 1.64140894351551e-24 38.9718069680618 7.36865661492034 5.28886186515329 1.80075376136673e-07 -69.8746882665908 12.8306201036897 -5.44593228557184 7.88552348264551e-08 NEK3 other 2.10609181542475e-20 0.00104759179466946 0.0018119184346872 5.28886186515329 -5.44593228557184 0.0387863702194878 31.9825137089747 12.8854267369915 2.48206864714533 0.0133793005456997 41.8141006330057 22.8356391831261 1.83108956564278 0.0676636277410564 PCDH8 other 1 1 1 2.48206864714533 1.83108956564278 1.72419113380911e-30 103.6790670902 33.5190613383326 3.09313754474477 0.00208550894832504 -506.884041827445 58.2861113420446 -8.69648069079202 4.36438705481037e-17 VPS36 other 2.36938345608048e-26 6.64434285224331e-13 1 3.09313754474477 -8.69648069079202 6.17848143964e-17 83.8482142994071 14.5101447691806 5.77859253875259 1.28006292157462e-08 -77.2522562993131 26.6958062160883 -2.89379746294221 0.00396134283689164 RNASEH2B other 6.77285135413336e-13 1 0.00013646750806907 5.77859253875259 -2.89379746294221 3.68090952856321e-10 311.808170340328 46.7682739018209 6.66708741474822 6.59872811301471e-11 221.231442822213 81.3250941725915 2.72033429623464 0.00673700348921259 CKAP2 other 3.08533836684168e-06 1 7.63802779081453e-07 6.66708741474822 2.72033429623464 4.08497888592888e-06 344.752159191121 69.3973638968406 4.96779906083459 9.18132436109294e-07 229.743982495419 122.300669140507 1.87851778825081 0.0608653184783608 CNMD other 0.0257190270658082 1 0.00885446921383803 4.96779906083459 1.87851778825081 5.02120740921855e-06 270.276797345335 55.2924159141344 4.88813507018861 1.35686726440787e-06 134.180172627727 105.93724443085 1.26660055534399 0.205863026172774 TBC1D4 other 0.0313323342335238 1 0.0129553686405663 4.88813507018861 1.26660055534399 3.43191664501927e-05 -18.590999557324 6.86669499218938 -2.70741595170174 0.00700106402075423 -54.7064053642575 11.9862654925706 -4.56409090872933 6.24874569801724e-06 THSD1 other 0.197918632918262 0.0763471749383746 1 -2.70741595170174 -4.56409090872933 5.67582004354101e-24 99.4815944086725 9.25903385282476 10.7442737536079 2.1680084885203e-24 55.2905582774714 17.3493787525645 3.18688980545189 0.0015271617964814 BORA essential 7.21680518536239e-20 1 3.09288090972305e-20 10.7442737536079 3.18688980545189 6.25857924992914e-08 -1.52867202234791 19.2130638344045 -0.0795641983768635 0.93661334648159 -178.774800075625 35.7090112410856 -5.00643377853971 7.51827997736773e-07 LRCH1 other 0.000459817817492294 0.00960610632708275 1 -0.0795641983768635 -5.00643377853971 9.63774549809303e-26 132.872127868787 23.8397260304475 5.57355934791726 3.94871012665742e-08 -237.855920642749 43.875078493272 -5.4212078658554 8.94513163575859e-08 SUCLA2 other 1.2579185424111e-21 0.00118594555226887 0.000412008414615436 5.57355934791726 -5.4212078658554 5.65350765520126e-21 52.6806939547763 28.2206086362937 1.8667454920524 0.0624788469860639 -385.452662652935 52.1971297453736 -7.38455667070657 5.83133542130393e-13 RCBTB1 other 6.82774119518656e-17 8.5878076749543e-09 1 1.8667454920524 -7.38455667070657 5.77108943355011e-55 187.788197966805 20.0760999789683 9.35381862829592 2.25257380117029e-19 -292.748914899103 36.9292008320511 -7.92730165568665 1.29582520687064e-14 MED4 essential 8.80033427722057e-51 1.93920242208191e-10 3.0781420992992e-15 9.35381862829592 -7.92730165568665 4.95769635798618e-30 68.5813211468828 22.0843376504595 3.10542802923753 0.00199976667525016 -346.163931842897 40.8474194351418 -8.47456061190209 2.25517398359454e-16 PHF11 other 6.78460746590409e-26 3.41749065473917e-12 1 3.10542802923753 -8.47456061190209 1.18635944384172e-40 133.141237627283 22.4027502110593 5.94307557656723 5.00468698011468e-09 -369.239277117318 42.7706500562635 -8.63300596627816 6.64665976017108e-17 COG3 essential 1.74205020733718e-36 1.01075754972922e-12 5.41957553076619e-05 5.94307557656723 -8.63300596627816 1.45659548839781e-05 312.749711983996 65.878659734204 4.74735996824807 2.66680762760876e-06 217.362305640856 126.405903200398 1.71955818626808 0.0861066917949783 LMO7 other 0.0873228995294489 1 0.0249933210859493 4.74735996824807 1.71955818626808 2.52243058274157e-06 65.1431691624348 12.6732799160637 5.14019808556933 3.89106140867129e-07 59.3334244279286 25.4613215459966 2.33033561595541 0.0201700462286952 SCEL other 0.0162343632305247 1 0.00384397956562637 5.14019808556933 2.33033561595541 3.11442441784154e-26 500.369376487986 295.220145582034 1.69490254637432 0.0906725680463954 -4737.30507600704 543.707655351332 -8.71296372118559 3.66340843924254e-17 ITM2B other 4.09235368504379e-22 5.57900471212246e-13 1 1.69490254637432 -8.71296372118559 0.532928656610434 16.5838949354359 21.1823903016345 0.782909515842329 0.434033254617024 -19.7545778989508 45.2879745204715 -0.43619919212817 0.662871527567275 SPRY2 other 1 1 1 0.782909515842329 -0.43619919212817 5.34860301144276e-20 126.461397336556 14.9517387581061 8.45797264000451 2.56694091956468e-16 6.52495295241002 27.5031387552811 0.237243938245307 0.812557696025831 NUDT15 other 6.33274596554822e-16 1 3.35909888734234e-12 8.45797264000451 0.237243938245307 0.047078991620907 -29.8501228519947 18.527645428205 -1.61111259213507 0.107761969034802 -89.3101569077102 37.2230662355844 -2.39932294514555 0.0167763507268833 EDNRB other 1 1 1 -1.61111259213507 -2.39932294514555 0.00196377539029994 -23.9923175586167 11.0431162438102 -2.17260391260162 0.0302475698203636 -72.065973784488 20.3888085665529 -3.53458484586047 0.000443730054452271 RCBTB2 other 1 1 1 -2.17260391260162 -3.53458484586047 0.163555385172972 407.188475420353 227.589651963409 1.78913440003775 0.0741504193180369 630.948723108077 423.954421615374 1.4882465919426 0.137266372108541 LCP1 other 1 1 1 1.78913440003775 1.4882465919426 2.81983189065043e-16 -3.51094064628427 12.1677339884288 -0.288545151432723 0.773040198522005 -169.871526620111 22.5055666901669 -7.54797819396085 1.89299462719565e-13 SETDB2 other 3.03244721520547e-12 2.80238924610044e-09 1 -0.288545151432723 -7.54797819396085 6.05597098082609e-05 372.701053469278 84.4503676241486 4.41325554825298 1.23084379345077e-05 127.011318688246 354.376181397577 0.358408170061947 0.720178468422059 SCRN1 other 0.338649897247795 1 0.11012359420004 4.41325554825298 0.358408170061947 3.84796366192064e-20 57.12218312121 7.14817911439195 7.99115162156495 7.94393137437616e-15 -106.375968594396 28.0150228597901 -3.79710447236785 0.000162750055966061 C7orf25 other 4.5675328666998e-16 1 1.01285125023296e-10 7.99115162156495 -3.79710447236785 0.266935497584389 -153.705523597901 101.375310872346 -1.51620273491887 0.130050008470511 -362.491874082402 412.491807095372 -0.878785633671 0.379906217557286 TNS3 other 1 1 1 -1.51620273491887 -0.878785633671 0.112353984913638 0.527807362949232 0.496972233499343 1.06204598038158 0.288686925248817 -2.9903206988452 1.95775379082931 -1.52742429249926 0.127237805765522 SPDYE1 other 1 1 1 1.06204598038158 -1.52742429249926 0.120628347887873 17.9526440868253 10.1160725227639 1.77466541945276 0.0765185481312525 66.1969714232498 46.2709018019276 1.43063931856396 0.153114155385113 IGF2BP3 other 1 1 1 1.77466541945276 1.43063931856396 0.000261982824578303 887.227408620982 295.624222732393 3.00119997076195 0.00281393994016845 4548.60588461184 1336.1866543134 3.40416952222078 0.000713135127083861 GPNMB other 1 1 1 3.00119997076195 3.40416952222078 0.0633724417116921 44.2873165553025 20.7871079938745 2.13051842364763 0.0335784233951115 -39.5476407946278 91.656873317902 -0.431474905951255 0.666294664448715 RAPGEF5 other 1 1 1 2.13051842364763 -0.431474905951255 5.62219947380741e-25 941.486801327784 106.77930097111 8.81712834571291 1.57470123016841e-17 -1579.96468010709 375.354719573336 -4.20925753085781 2.9957305666797e-05 RAC1 essential 7.26163284036965e-21 0.350470518995858 2.10196553296209e-13 8.81712834571291 -4.20925753085781 1.39567266271412e-12 1309.79250257856 183.54999515992 7.13588960564879 3.07497405544209e-12 -362.657707188435 645.222026500993 -0.562066532593609 0.574301349692212 KDELR2 other 1.31165316841873e-08 1 3.69765630166911e-08 7.13588960564879 -0.562066532593609 2.19604456455906e-08 45.3091546689829 8.36849239203772 5.41425534569317 9.29475625871257e-08 -50.5684772000869 37.8171203183052 -1.33718476643526 0.181728467070405 NUPL2 other 0.000166504098884868 1 0.000951411250641818 5.41425534569317 -1.33718476643526 0.6067502127762 9.32072979489079 9.71450703892116 0.959465030757329 0.337753123735335 21.84934362986 43.5269988712114 0.501972205676488 0.615891301623993 IL6 other 1 1 1 0.959465030757329 0.501972205676488 8.24234917678991e-13 103.58421638585 21.229255502501 4.87931460307909 1.3990217706471e-06 -327.555208068025 74.6258982164334 -4.38929669051399 1.36564204388678e-05 ZDHHC4 other 7.80797737517309e-09 0.163590260437198 0.0133365930774246 4.87931460307909 -4.38929669051399 0.768392543737882 -1.27383483437754 8.20212104309099 -0.155305539589731 0.876638056220647 20.2825688378077 31.3719824775044 0.646518556879582 0.518216246427869 AOAH other 1 1 1 -0.155305539589731 0.646518556879582 5.77652128945314e-10 425.228093638656 75.2608644544239 5.65005593174078 2.60948559915046e-08 -551.935297350704 277.633464613025 -1.98799989086333 0.0473209142193542 BZW2 other 4.79335736598822e-06 1 0.000274726643878561 5.65005593174078 -1.98799989086333 7.30341508718313e-15 273.001714703024 33.0042681537934 8.27170938712804 1.06924584829767e-15 94.9011146803255 133.242315328263 0.712244563196923 0.476626168431894 TBRG4 other 7.50352866057195e-11 1 1.38328335394269e-11 8.27170938712804 0.712244563196923 9.67741386930119e-21 268.011450929182 30.695313381013 8.73134760353887 3.24751298103839e-17 -383.251593703627 121.314773279098 -3.15915022832309 0.00167204366137575 DDX56 essential 1.16341869536739e-16 1 4.31626950309812e-13 8.73134760353887 -3.15915022832309 8.14605552828563e-12 36.1556725568483 6.68371971995742 5.40951357503642 9.48257425568807e-08 -101.053654769462 27.1635582568377 -3.72019209758812 0.000219751401602121 HUS1 essential 7.42268579737387e-08 1 0.000970256997842003 5.40951357503642 -3.72019209758812 0.588945113933487 -0.288624366367523 7.15196031249762 -0.0403559798651523 0.967824550495501 -28.8624761526973 28.3920257421762 -1.01656980783242 0.309822827620108 NACAD other 1 1 1 -0.0403559798651523 -1.01656980783242 3.5738659666464e-09 144.768177277269 24.5310419849447 5.90142796894304 6.38775375825429e-09 -107.762139950958 96.544377063658 -1.11619281441843 0.264838812907967 CCM2 other 2.84193821667722e-05 1 6.89174752978055e-05 5.90142796894304 -1.11619281441843 0.314072112119315 11.7159927590028 9.99041125641316 1.17272377065378 0.241425578798712 46.7265064507804 39.3200038957406 1.18836474621616 0.235214049016543 MYO1G other 1 1 1 1.17272377065378 1.18836474621616 1.11627978163315e-10 719.487371855301 104.173663259933 6.9066148711699 1.40287000897331e-11 521.187625620748 366.255971726412 1.42301468332117 0.15531041703354 TTYH3 other 9.60447124117164e-07 1 1.65749091560197e-07 6.9066148711699 1.42301468332117 8.11422448773739e-10 85.8009038668232 20.0868307678807 4.27150031074195 2.29952581141854e-05 -189.222085400934 55.075314469204 -3.43569686754562 0.000637117306657627 CIDEB other 6.67476106361277e-06 1 0.20125449901535 4.27150031074195 -3.43569686754562 3.35763564840293e-33 69.6161012992142 8.56295009466439 8.12992024122531 2.87924177908533e-15 -153.993587586068 22.5930205563976 -6.81598050166258 2.47613365957496e-11 TTC5 other 4.72721522938648e-29 3.57429893759646e-07 3.69781021687929e-11 8.12992024122531 -6.81598050166258 1.75751366641707e-10 15.6177716443689 4.85828622225159 3.21466684544798 0.00138415424063171 -78.555089701106 16.0745732624198 -4.88691602686319 1.35296009647735e-06 ZFHX2 other 1.50038941702025e-06 0.017085180098316 1 3.21466684544798 -4.88691602686319 1.3418632320441e-26 124.432961148437 12.4173593981067 10.020887465608 8.31131853826746e-22 -92.0696734950162 30.4422322174233 -3.02440612230535 0.00260860207295955 MTHFS other 1.77179621159103e-22 1 1.1609249734252e-17 10.020887465608 -3.02440612230535 0.000101063824020575 4.56217901292317 10.4770020046089 0.435446992461799 0.663411679898831 108.347390623044 25.3523486341384 4.27366285414474 2.27247898648798e-05 ADAMTS7 other 0.548978692079766 0.268220694775176 1 0.435446992461799 4.27366285414474 1.70946013395197e-09 246.363642431149 43.6303970241538 5.64660556021898 2.64561147474719e-08 -130.272998317133 88.5367025208212 -1.47140106428175 0.141764106828234 ABHD17C other 1.38363703242073e-05 1 0.000278450607717142 5.64660556021898 -1.47140106428175 1.27671021188532e-24 394.21479549817 38.6853389869484 10.1902892884348 1.98211717426438e-22 -136.912265508531 93.4531598630686 -1.46503623536262 0.143490848050891 IREB2 other 1.64070029329383e-20 1 2.78427999468918e-18 10.1902892884348 -1.46503623536262 0.00326798519170372 137.261133467968 41.8538652147972 3.27953303150219 0.00110680263534984 -1.19670272194801 109.515322533861 -0.0109272629095166 0.991285514875837 ALPK3 other 1 1 1 3.27953303150219 -0.0109272629095166 7.38951358991689e-06 6.28536559755502 7.01675552836603 0.895765225415895 0.37078481683631 -64.8458749899136 14.8658078058004 -4.3620821577292 1.54872781592192e-05 TM6SF1 other 0.045438119064399 0.18485615210844 1 0.895765225415895 -4.3620821577292 1.15217526244451e-06 33.1604929484052 11.3974607721077 2.90946322268175 0.00376913675318114 138.484369871637 27.5331366212968 5.02973459858254 6.68847355820162e-07 CIB2 other 0.00764583504158175 0.00855923961243062 1 2.90946322268175 5.02973459858254 3.121669233563e-56 608.487761756688 38.6076511584567 15.7608075989726 4.47647811267283e-46 -1012.43962667798 182.90157989008 -5.53543401476598 4.91832633278806e-08 CALCOCO2 other 4.7717835904244e-52 0.000657580230693764 6.83065795212747e-42 15.7608075989726 -5.53543401476598 7.01794903830473e-89 294.074329278522 13.0065808868643 22.609656745034 1.52226484144975e-79 -351.279645261266 63.3460444525027 -5.54540774088362 4.65282329743388e-08 RSAD1 other 1.09381753711018e-84 0.00062273387012855 2.37031858462141e-75 22.609656745034 -5.54540774088362 7.72342282539041e-50 483.796433966782 40.8977279705167 11.8294208009685 7.45113377024134e-29 -657.372926950667 100.315809571455 -6.55303416040739 1.32354509633638e-10 NMT1 essential 1.16762706274252e-45 1.88737530737567e-06 1.08965380256009e-24 11.8294208009685 -6.55303416040739 4.07469906369172e-11 3.71801385284551 1.18649582515062 3.13360887921668 0.00182336255036939 -32.5369246106622 5.77942080181124 -5.62978985722329 2.94447175654306e-08 MYCBPAP other 3.58695758576782e-07 0.000396649790323916 1 3.13360887921668 -5.62978985722329 8.7902818130948e-15 444.876358885445 53.6005209983041 8.2998513932266 9.10744962481273e-16 394.867129580029 195.149692502856 2.02340636316529 0.043544262056676 SRSF1 essential 9.00036954842776e-11 1 1.17996117339074e-11 8.2998513932266 2.02340636316529 8.39253090437205e-22 299.719767163472 37.1596520191553 8.06573126704659 5.09104911100743e-15 -621.343985138516 135.938412484794 -4.57077564597881 6.08275280640436e-06 VEZF1 other 1.03018316851167e-17 0.0743920668223253 6.5104336031563e-11 8.06573126704659 -4.57077564597881 5.53439331603389e-07 121.501177414568 59.5615036068172 2.03992797456277 0.0418565265084854 -1305.58621959312 287.597826868225 -4.53962477328222 6.99140230568052e-06 CHAD other 0.00377556312019832 0.0852251941062455 1 2.03992797456277 -4.53962477328222 7.72351676524374e-93 207.586218993951 8.28937883134011 25.0424336030004 1.50315191385679e-91 -21.3294587391687 38.0934338303436 -0.559924811036031 0.575770457684693 TACO1 other 1.20502308571333e-88 1 2.34566856157352e-87 25.0424336030004 -0.559924811036031 3.91552564254798e-37 483.371196881295 36.2535662781622 13.3330661367916 4.39010299180666e-35 -321.603899567994 164.143752160188 -1.95928200333901 0.0506146810067219 TEX2 other 5.65597679066055e-33 1 6.56100892125505e-31 13.3330661367916 -1.95928200333901 1.12361561266024e-44 824.094548641014 52.8898578399438 15.5813341592807 3.15911152256384e-45 170.166538651183 243.535211501897 0.6987348466029 0.485028935969621 DCAF7 other 1.67564796316022e-40 1 4.81353822693052e-41 15.5813341592807 0.6987348466029 2.09084549771419e-10 114.564031652314 17.1326059781962 6.68690050994658 5.85547560721001e-11 200.482544018412 78.8781423994206 2.54167425753024 0.011319261526624 LIMD2 other 1.77972768765432e-06 1 6.78708177631713e-07 6.68690050994658 2.54167425753024 3.12367704349045e-26 105.336166541652 9.51426018190921 11.0713985667474 1.14050559611728e-25 181.864748747568 36.7361255862976 4.95056965983922 1.00849192648452e-06 BRIP1 other 4.10419926744211e-22 0.0128038134986475 1.63970489553781e-21 11.0713985667474 4.95056965983922 3.69190246264941e-78 472.582075391094 22.477176923492 21.0249746665105 1.88455896239293e-71 -390.784380437292 98.9615696551853 -3.94884985958603 8.9368527800716e-05 KAT7 other 5.73832399769598e-74 1 2.92690852449247e-67 21.0249746665105 -3.94884985958603 3.77394518773737e-05 87.9861066536449 19.3192599180302 4.55432076730484 6.50385889283618e-06 18.5807847894425 80.9096398089076 0.229648591111351 0.818451965699029 RTP4 other 0.216775411583634 1 0.0594192548449513 4.55432076730484 0.229648591111351 5.51422775172229e-38 492.037525916015 34.7339737065609 14.165886404845 7.15321590173699e-39 159.467373730925 142.361535827502 1.1201577224072 0.263152940824732 ACTL6A essential 8.00335015884974e-34 1 1.07906261877702e-34 14.165886404845 1.1201577224072 3.32873380197191e-28 336.729014825025 28.4874555813112 11.8202558969826 8.76892352394526e-29 -232.129232423669 116.759399964858 -1.98809888106254 0.0473137719165113 NDUFB5 other 4.47714696365222e-24 1 1.28149048378936e-24 11.8202558969826 -1.98809888106254 3.23807507889779e-37 292.269838605583 20.8172606095972 14.0397838162645 2.62529020099652e-38 42.6139775345943 85.3221464707863 0.49944802489451 0.617670665068576 MRPL47 other 4.67869468149942e-33 1 3.95342451368066e-34 14.0397838162645 0.49944802489451 4.7901723795233e-13 296.703289062439 38.7818162080672 7.65057746317512 9.17718688276048e-14 190.917939201757 156.343216269568 1.22114629439742 0.222560580061556 TRA2B essential 4.57892577758632e-09 1 1.14356925746078e-09 7.65057746317512 1.22114629439742 0.262990636761982 17.6975405087907 12.073336287201 1.4658367900803 0.143273712392066 33.6727815782423 30.1820941360022 1.11565424938743 0.265065468720909 SCN2A other 1 1 1 1.4658367900803 1.11565424938743 2.38106774770999e-12 140.524647215868 65.189413347714 2.15563601510452 0.0315483638660132 -1003.07940026697 163.111229627915 -6.14966487932909 1.5011399016058e-09 MARCH7 other 2.21701217989278e-08 2.09454050471058e-05 1 2.15563601510452 -6.14966487932909 0.456791490727127 7.72538228849275 6.86981097948447 1.12454073504545 0.261281471230731 14.870583488409 17.0543481368624 0.8719526169556 0.383620311920632 ERMN other 1 1 1 1.12454073504545 0.8719526169556 0.0551122237672768 -158.204214650998 118.667962742345 -1.33316702330599 0.18303707059195 -685.126290877459 294.593949577931 -2.32566314365603 0.0204046180260631 GALNT5 other 1 1 1 -1.33316702330599 -2.32566314365603 0.00028986896544834 -26.9332841638183 7.72358303263196 -3.48714891133115 0.000527966626625472 -58.1739572803187 19.2878266729757 -3.01609705783112 0.00268105482045697 SCN7A other 1 1 1 -3.48714891133115 -3.01609705783112 6.13606799891195e-05 95.639853843977 35.4140102712563 2.70062196038845 0.00713624252664715 -221.856662226189 87.6402876761647 -2.53144607473175 0.0116393030901497 TANK other 0.342760758419221 1 1 2.70062196038845 -2.53144607473175 0.0781754626895124 -5.12625634166237 2.61643450334112 -1.95925269106346 0.0505963540538438 -1.81650191052378 5.45033922560163 -0.333282358278033 0.739050279707505 BLK other 1 1 1 -1.95925269106346 -0.333282358278033 3.68192964194935e-05 37.0029394515189 8.59988788176702 4.30272347270601 2.00247872903478e-05 69.228936350146 17.9145727507859 3.8643922639522 0.000124878031136396 GATA4 other 0.211674135115668 1 0.175957805920286 4.30272347270601 3.8643922639522 0.0405819165537469 248.778819650546 108.397138229683 2.29506815136953 0.0221168338425838 -486.844389408543 463.902357592102 -1.049454441093 0.294444621705274 SKIL other 1 1 1 2.29506815136953 -1.049454441093 4.64156118117587e-13 842.310854030205 108.807471519614 7.74129609177041 4.97692711764722e-14 525.51198161006 679.291395497576 0.773617898140939 0.43949975889426 EPRS essential 4.44011742591284e-09 1 6.24206199095315e-10 7.74129609177041 0.773617898140939 0.135012793074031 -1.64807310132001 3.440733665122 -0.47898886159838 0.632141897123829 -42.6984643755046 21.5361535981396 -1.98264115181613 0.0479176271365185 HLX other 1 1 1 -0.47898886159838 -1.98264115181613 6.18638915055348e-33 188.147470329618 14.6707204687713 12.8246919249887 7.87518806144801e-33 344.604274414473 179.001029085505 1.92515247635734 0.0547660805796283 VPS45 other 8.69682586784808e-29 1 1.16907166772196e-28 12.8246919249887 1.92515247635734 0.324273635794657 0.908584515656326 0.604787200008966 1.50232100752605 0.133603119140058 0.0780400258958372 4.72979148054834 0.0164996757714972 0.986841900465696 IL10 other 1 1 1 1.50232100752605 0.0164996757714972 4.06956637169453e-08 640.514669169678 117.983803316506 5.42883557882449 8.66215850474101e-08 -1219.59027921579 731.998982536264 -1.66610925467423 0.0962847556424809 KCTD3 other 0.000302938520708941 1 0.000888304354661191 5.42883557882449 -1.66610925467423 1.2919178021281e-24 142.875809861985 13.2549846599479 10.779024912319 1.20360849182993e-24 -73.8070695276541 81.3179623047209 -0.907635501872004 0.364480234961088 RPS6KC1 other 1.65998518395439e-20 1 1.7197158131266e-20 10.779024912319 -0.907635501872004 0.00570877535554295 17.7447709067525 19.6209933927489 0.904376784169869 0.366195966902658 -147.733283428821 52.3831815908134 -2.82024266076135 0.00497380542617916 CBWD2 other 1 1 1 0.904376784169869 -2.82024266076135 0.219373702679553 -5.96436095627336 26.1972149064214 -0.227671566522569 0.819986963333992 -121.466373639209 69.945834943931 -1.73657764949947 0.0830268033505184 IL1RN other 1 1 1 -0.227671566522569 -1.73657764949947 2.63468086034893e-07 234.561783584555 92.0954540671601 2.54694203921838 0.0111434395692528 -1055.06222614532 255.61670067089 -4.12751679908319 4.24697026568546e-05 SMPD4 other 0.00184559394267442 0.492096444684974 1 2.54694203921838 -4.12751679908319 1.07963233239043e-20 141.119406319252 25.3160686850931 5.5743017636205 3.92320395386237e-08 -413.467924798055 65.151568461517 -6.34624667619902 4.66387665286441e-10 WDR33 essential 1.295774725335e-16 6.58072995719169e-06 0.000409464796664615 5.5743017636205 -6.34624667619902 6.39197833634563e-15 29.675160667524 22.759639592862 1.30385020142546 0.192841232018027 -484.438374744652 63.7131385274554 -7.60342977823792 1.29000377815727e-13 CCDC115 essential 6.58245929076873e-11 1.91320460338504e-09 1 1.30385020142546 -7.60342977823792 1.77801932041584e-15 140.088715671792 19.6366832194555 7.13403145053518 3.12575871649633e-12 -118.20554971488 50.6052166225556 -2.33583724374759 0.0198621228699248 SAP130 essential 1.86425325745601e-11 1 3.75747455310023e-08 7.13403145053518 -2.33583724374759 0.227192020631917 108.074158609682 69.2597192872831 1.56041866357269 0.119246816244965 -36.4082724644555 164.170440766706 -0.221771180575639 0.824575856723514 BIN1 other 1 1 1 1.56041866357269 -0.221771180575639 1.01035172942346e-15 202.239439923928 27.7147731956311 7.29717102486728 1.05821913921698e-12 -189.852125595819 77.5844967432635 -2.44703688965159 0.0147218303152815 IMP4 essential 1.06854798903825e-11 1 1.28520714457902e-08 7.29717102486728 -2.44703688965159 4.47152572709665e-05 193.206608757566 80.6020315790926 2.39704390785706 0.0168643027741668 -628.022537936035 209.255044656331 -3.00123009682976 0.00281227385530995 HS6ST1 other 0.254742820672696 1 1 2.39704390785706 -3.00123009682976 1.87634596977432e-19 614.648459119893 74.4606598895756 8.2546738107265 1.1590333931845e-15 -485.243051898454 193.311116420726 -2.51016631057244 0.0123565759014882 UGGT1 other 2.1966382268148e-15 1 1.49851427404824e-11 8.2546738107265 -2.51016631057244 0.249574819804928 0.237793598923944 33.3076282674981 0.00713931346339616 0.99430633218364 -124.582620482342 78.6715609393105 -1.58357885613136 0.113873955428543 GYPC other 1 1 1 0.00713931346339616 -1.58357885613136 1.09528671810863e-26 154.622129878044 13.4437326859463 11.5014284715495 1.47286585789738e-27 30.4545552854315 52.9443766365062 0.575217940415461 0.565381306214395 STAM other 1.44774998399599e-22 1 2.14007409152489e-23 11.5014284715495 0.575217940415461 7.1917305522684e-18 326.377467213815 36.8605595686459 8.85438178457379 1.17126129013344e-17 -52.6432273479781 134.413857409682 -0.391650298283799 0.695469145099266 ABI1 other 8.09429273657808e-14 1 1.56632772329545e-13 8.85438178457379 -0.391650298283799 9.85340866217688e-20 855.162736934492 97.0291179561807 8.81346501903369 1.6134096015527e-17 -664.107116971523 351.240582315965 -1.89074711296918 0.0591863322529835 YME1L1 other 1.16112567675092e-15 1 2.15325645423224e-13 8.81346501903369 -1.89074711296918 0.0196570725401749 -70.6865339849764 162.63625440299 -0.434629623293125 0.664005560319457 -1761.35174454856 627.202691541122 -2.80826560265659 0.00516183654388268 DNAJC1 other 1 1 1 -0.434629623293125 -2.80826560265659 3.97519449885154e-13 81.9714708944767 17.9467702692135 4.56747758314449 6.10198758891284e-06 -162.834829219764 37.9837329925733 -4.28696224385323 2.14033671191643e-05 NIPSNAP3A other 3.81340408274829e-09 0.253180429652595 0.0558697983640859 4.56747758314449 -4.28696224385323 1.00483978530314e-13 155.094687523169 40.0041088554238 3.87696894045776 0.00011868970810216 -459.917740926028 88.3801272660737 -5.20385922891261 2.77035928843233e-07 LRRC8A other 9.88259928845636e-10 0.00359786560788707 0.973374296145814 3.87696894045776 -5.20385922891261 4.2746854141728e-09 820.577564191222 151.724787345894 5.40832897870874 9.5217836214706e-08 -408.530870621596 322.288157686966 -1.26759504151064 0.205481937093068 TXN essential 3.38213109969352e-05 1 0.000974078464476442 5.40832897870874 -1.26759504151064 2.83041198227559e-24 342.324898177597 44.7478605175477 7.65008414298056 9.23323261504643e-14 -487.105614664168 101.29945074635 -4.80857113316305 1.9722052276608e-06 ODF2 other 3.61783259574466e-20 0.0247077870921345 1.15046078383478e-09 7.65008414298056 -4.80857113316305 8.33004983692759e-21 500.991274028213 93.1785013823342 5.37668310389028 1.12711149464367e-07 -1259.09080814798 202.42982085076 -6.21988797330526 9.9150570260271e-10 KIAA0368 other 1.00310460136282e-16 1.38900033877614e-05 0.00114717407924833 5.37668310389028 -6.21988797330526 6.2576510352608e-17 116.094184875059 19.5544157628807 5.93698048987154 5.18779569592823e-09 -184.8138975045 43.2320656696034 -4.27492636870329 2.25936778686882e-05 TOR1B other 6.85713400443879e-13 0.266740960917733 5.61475128170312e-05 5.93698048987154 -4.27492636870329 8.03034703402558e-31 215.297765446166 27.2357516947893 7.90496872856117 1.50836353666477e-14 -391.549494459031 60.2144201140113 -6.50258681753744 1.79494393623807e-10 C9orf78 essential 1.10674242822941e-26 2.55420522126678e-06 1.9123032917836e-10 7.90496872856117 -6.50258681753744 1.89999114114132e-07 234.454557679537 45.079789017428 5.20087965781951 2.80606096577887e-07 -25.2660080498839 95.5192628988279 -0.264512175692197 0.79148473694166 SMC2 essential 0.00134671372084097 1 0.0027942755097226 5.20087965781951 -0.264512175692197 0.00235123635158768 -21.578549945886 77.906593418959 -0.276979765112342 0.781900662811004 -551.750210404756 163.186121242411 -3.38110990201879 0.000773694365737851 KLF4 other 1 1 1 -0.276979765112342 -3.38110990201879 1.70128677642938e-31 145.305569043253 19.7112090772576 7.37172278340366 6.33557746943073e-13 -316.024615435431 43.578713656733 -7.2518114675146 1.42761310887619e-12 TOR1A other 2.36053540229577e-27 2.09416566941048e-08 7.73320585918716e-09 7.37172278340366 -7.2518114675146 1.95492058401737e-20 33.0638414724528 15.5244659240934 2.12978930380716 0.0336388895395129 -295.258804883026 34.8216083501532 -8.47918344017923 2.16082272190043e-16 RALGPS1 other 2.33456616143354e-16 3.27494291731229e-12 1 2.12978930380716 -8.47918344017923 1.51352066526269e-15 1053.88900904932 146.576148198218 7.19004436945715 2.16512284180276e-12 -653.266782265664 337.141506528418 -1.93766347250572 0.0531843480398266 FAM129B other 1.59025616299151e-11 1 2.61265373320338e-08 7.19004436945715 -1.93766347250572 5.15201375669314e-05 78.8563228432406 29.2821361506288 2.69298395573327 0.00730077615597173 -162.888844194549 66.1538090854898 -2.46227460589684 0.0141159548655708 ST6GALNAC4 other 0.29062509601506 1 1 2.69298395573327 -2.46227460589684 5.08161672557091e-06 101.56795086924 26.4884352350918 3.83442623045859 0.000140608965410395 -96.2227219703588 55.0775118772918 -1.74704191766569 0.0811954161856137 TMOD1 other 0.031678798667209 1 1 3.83442623045859 -1.74704191766569 0.000140425228443577 109.467318996014 56.7148957521888 1.93013347806056 0.054113667356607 -440.846524846445 141.357095467101 -3.1186727725956 0.00191355906463717 DAB2IP other 0.748185617147376 1 1 1.93013347806056 -3.1186727725956 2.15786105623406e-15 159.787341956532 31.2697485062681 5.10996568854728 4.47525149725213e-07 -334.285307464345 71.2718275411343 -4.69028673737057 3.45905254191065e-06 STXBP1 other 2.25539637597584e-11 0.0428126933112282 0.00440499004874527 5.10996568854728 -4.69028673737057 6.23563677771981e-10 42.6218991336913 16.5732938932478 2.57172167513762 0.0103857691213054 -182.33540593791 37.1930388078254 -4.90240678853987 1.25405631263879e-06 SLC2A8 other 5.16435437930755e-06 0.0158537799043796 1 2.57172167513762 -4.90240678853987 0.00325745575720131 18.896477190472 113.283442776368 0.166807052534371 0.867584080691646 -797.914021254482 252.632499185878 -3.1583981626505 0.00167476761432688 ANGPTL2 other 1 1 1 0.166807052534371 -3.1583981626505 9.19268504501236e-15 202.233261970987 49.2486503585692 4.106371656859 4.64673934622493e-05 -618.385607267821 111.274851593589 -5.55728089870983 4.32370219989663e-08 CDK5RAP2 other 9.40411680104764e-11 0.000579246383720152 0.395885500228986 4.106371656859 -5.55728089870983 5.1152997619905e-05 5.09820755405307 3.99872895966625 1.27495701896199 0.20286971292987 -32.3246622318335 8.87807243253698 -3.6409550020529 0.000297623802226516 ZFP37 other 0.288656365569124 1 1 1.27495701896199 -3.6409550020529 4.6406386715376e-05 67.930730582885 33.7286617333492 2.01403575154951 0.0444966503857866 -236.151163426682 75.0989369678208 -3.14453403685156 0.00175416644456552 SLC31A2 other 0.264005934023774 1 1 2.01403575154951 -3.14453403685156 1.08779415720952e-08 284.984658945534 56.2689823302241 5.06468478980218 5.6040790999644e-07 -204.537683533363 124.842584498483 -1.63836470027459 0.101921728663172 SLC31A1 other 8.390156334557e-05 1 0.00547462487275522 5.06468478980218 -1.63836470027459 0.171798366007839 2.32841796932664 20.9860782866463 0.110950599608133 0.911696898232757 -81.6766988274325 46.4604852683519 -1.75798204335738 0.0793191826908511 TLR4 other 1 1 1 0.110950599608133 -1.75798204335738 1.18631917928627e-13 22.475198711427 15.6497237643348 1.43614028272162 0.151537212896648 -225.202637767607 32.7097909732809 -6.88486936378054 1.60025573895243e-11 ZNF189 other 1.16413501063362e-09 2.31653020770754e-07 1 1.43614028272162 -6.88486936378054 0.758175952309465 -13.7982292383914 24.2827099454375 -0.568232675405486 0.570111455258444 -32.5690847437541 50.7537627207335 -0.641707786730249 0.521333220569131 ALDOB other 1 1 1 -0.568232675405486 -0.641707786730249 5.30142762918024e-10 79.262446607911 15.2968956375315 5.18160341065789 3.11040051603203e-07 -72.7880284286472 32.0361602899535 -2.2720584417688 0.0234746667118169 STX17 other 4.4091973591892e-06 1 0.00308987187262622 5.18160341065789 -2.2720584417688 5.64205674419727e-18 194.475656795472 30.2622209966063 6.42635108696354 2.85045823104819e-10 -279.143550431685 67.1420332379335 -4.15750815055711 3.73526043486341e-05 PRPF4 essential 6.36480421312894e-14 0.434224025552872 3.23869064211696e-06 6.42635108696354 -4.15750815055711 1.50849319495472e-11 101.708316203555 36.3665141821657 2.79675736019354 0.00534515724789224 -438.254329878896 82.372933806328 -5.32036810670484 1.51777756356378e-07 FPGS other 1.35417434111085e-07 0.00199284194095924 1 2.79675736019354 -5.32036810670484 3.67899902770989e-25 86.0908886778107 19.7247854937036 4.36460455832546 1.52597314900126e-05 -358.981505702285 43.7620234312534 -8.2030371896815 1.71778751504259e-15 USP20 other 4.76246424137046e-21 2.5892211214237e-11 0.135399597510882 4.36460455832546 -8.2030371896815 0.000245428795765672 -57.0686640820437 123.263891223141 -0.462979575898137 0.643564156027625 -1163.82539639759 289.243512586429 -4.02368712089897 6.54100634699732e-05 KIF12 other 1 0.747571615398324 1 -0.462979575898137 -4.02368712089897 4.59176513274789e-22 429.588142060214 101.651958883271 4.22606850649595 2.78794178090715e-05 -1776.01047354298 230.414856844876 -7.70788176536142 6.09768176738261e-14 ATP6V1G1 essential 5.66577899729763e-18 9.07335046986532e-10 0.242244261343022 4.22606850649595 -7.70788176536142 3.63645831756518e-08 118.502759988208 20.04121683908 5.91295233915788 5.95136376101616e-09 105.927040866258 41.8302038444245 2.53230993710247 0.0116125595189138 TEX10 essential 0.000271936269191541 1 6.42747286189746e-05 5.91295233915788 2.53230993710247 3.00251542156804e-10 0.499181188794561 9.88803501565317 0.0504833556924441 0.959755845702529 -140.894833087714 22.1890827441142 -6.34973670216663 4.57250176786687e-10 GARNL3 other 2.52961924267107e-06 6.45317174499052e-06 1 0.0504833556924441 -6.34973670216663 1.60540511434449e-24 63.1024396900379 11.8460157527271 5.32689142132122 1.46490287706627e-07 -181.668168994665 24.7595871321992 -7.33728587737274 7.97307071120721e-13 MRPL50 essential 2.06005584272685e-20 1.17220085596168e-08 0.00148057733785088 5.32689142132122 -7.33728587737274 5.23160610088849e-13 255.244660104844 42.4720321135095 6.00971150668479 3.41396069934062e-09 -242.391430658183 95.9522450635679 -2.52616737104588 0.0118151306462043 DPM2 other 4.99304486268798e-09 1 3.71916878586167e-05 6.00971150668479 -2.52616737104588 0.0677552615642801 1.85603841818876 2.23473606500919 0.830540325208883 0.406598376351369 -9.17844753599258 5.08540488159976 -1.80486072391255 0.0716503353111301 WDR38 other 1 1 1 0.830540325208883 -1.80486072391255 4.03510326765869e-22 67.9278885968427 17.631114635436 3.85272797559365 0.000130732887076239 -288.574227720163 36.6980043310622 -7.86348557586021 2.02021085823742e-14 TSTD2 other 4.98335253555848e-18 3.01819502220671e-10 1 3.85272797559365 -7.86348557586021 0.160266294498673 26.9487072788392 29.0831816944953 0.926607946885669 0.354541779349932 115.523480592767 61.1362285146229 1.88960757638388 0.0593429002373007 GABBR2 other 1 1 1 0.926607946885669 1.88960757638388 3.75866361727209e-12 417.058789438502 63.3582211518592 6.58255206437822 1.09009839299799e-10 -176.728759377153 143.792372561082 -1.22905517329913 0.219582486733625 PSMB7 essential 3.47112585055077e-08 1 1.25448523066209e-06 6.58255206437822 -1.22905517329913 2.91466642068121e-25 7.99955774766449 6.92080739710154 1.15587059264425 0.248241479883839 -146.31266570137 14.4052049507305 -10.1569305123944 2.60449786896975e-22 TRMO other 3.77915648105525e-21 4.0380134960507e-18 1 1.15587059264425 -10.1569305123944 4.35855600353429e-16 46.0815566530273 14.0451313597829 3.28096302359821 0.00110106568062418 -212.178239668031 32.1592187457342 -6.59774235641767 9.94571979900630e-11 RABEPK other 4.65929636777815e-12 1.42213847405991e-06 1 3.28096302359821 -6.59774235641767 1.14581190637901e-29 123.375381206354 21.2205303325603 5.81396314196021 1.04273352471287e-08 -408.78254954874 48.4615042040842 -8.43520142972139 3.01484494508958e-16 GOLGA1 other 1.56346034625416e-25 4.56447524686562e-12 0.000111530777803288 5.81396314196021 -8.43520142972139 2.55673363768332e-26 -2.87528689834655 7.01482473078862 -0.409887204412492 0.682050051464533 -160.155972319528 14.6008958409655 -10.9689141038991 1.9871355643556e-25 XPA ts 3.36389444709995e-22 3.09555978215316e-21 1 -0.409887204412492 -10.9689141038991 5.77828544920819e-16 272.897542270069 37.5910926316558 7.25963315150515 1.34852156437561e-12 -162.811212380854 78.2433844218354 -2.08083039331589 0.0379166952865162 NCBP1 essential 6.15502966049657e-12 1 1.63467784033611e-08 7.25963315150515 -2.08083039331589 1.02571154394006e-08 769.660380405952 124.763148338011 6.16897209359267 1.34257965237082e-09 547.565234582849 260.581856983825 2.10131757030513 0.0360724901023511 ANP32B other 7.92259596539301e-05 1 1.48663844907021e-05 6.16897209359267 2.10131757030513 3.01966657773936e-24 94.7954532881524 11.0843301115808 8.55220408756238 1.25435215536815e-16 -118.155754679258 27.5184256409983 -4.29369602101161 2.08417366062243e-05 PDCL other 3.85792601971981e-20 0.24674531968109 1.65035113081787e-12 8.55220408756238 -4.29369602101161 0.003436617638115 256.832273110342 291.875794943499 0.879936868900206 0.379282770163556 -1880.81165230291 664.197716977543 -2.83170448230629 0.00480182357341035 RPL35 essential 1 1 1 0.879936868900206 -2.83170448230629 5.17284266942403e-05 109.105010381995 30.0500955018527 3.63077083649429 0.000309530605529265 228.575910964848 61.9419416198458 3.69016380480417 0.000246881516553176 CTSV other 0.291593141275432 1 1 3.63077083649429 3.69016380480417 3.70288426520671e-16 184.988610550982 97.5524334414076 1.8962992928525 0.0584510133220032 -1607.90279260476 217.179009594133 -7.40358285825886 5.08472972777612e-13 LMX1B other 3.96727020174247e-12 7.49438314576922e-09 1 1.8962992928525 -7.40358285825886 1.47268275967817e-10 214.142105194808 31.5289091931841 6.79192876235315 2.91273421197819e-11 81.0084748349976 71.7477429361997 1.12907349443777 0.259365386636143 ARPC5L other 1.26100550658779e-06 1 3.40819030143568e-07 6.79192876235315 1.12907349443777 0.220833192189767 57.8023436001383 34.2422985395107 1.68803923993136 0.0919908771674415 -151.672104297866 389.211096867394 -0.389691109833751 0.696921218904449 ENPP2 other 1 1 1 1.68803923993136 -0.389691109833751 1.17067772597772e-49 82.0819979062975 4.99768819453755 16.4239933967895 2.56079736171381e-49 206.611637400489 56.7722415517349 3.63930737545759 0.000300096798777086 DSCC1 other 1.76865990840714e-45 1 3.9218611594647e-45 16.4239933967895 3.63930737545759 4.52918583166817e-81 686.777259658747 29.7558810325908 23.0803873327272 2.58067180161447e-82 -65.6528004449342 332.60027257511 -0.197392503429498 0.843595366367763 DERL1 other 7.04650731690934e-77 1 4.02146086845583e-78 23.0803873327272 -0.197392503429498 0.0006034780262002 204.522390671005 53.4897004196696 3.82358452312058 0.00014734429821664 475.82319875795 605.669963383808 0.785614654059418 0.432448356814212 MYC og 1 1 1 3.82358452312058 0.785614654059418 0.178374643104167 5.95022236630145 8.9911347781123 0.661787695674017 0.508394912639447 182.887553061183 104.395107122029 1.75187858993624 0.0803730248645416 NOV other 1 1 1 0.661787695674017 1.75187858993624 0.353936622008471 -36.2898968076814 29.4836854208321 -1.23084669673081 0.218913087371933 -82.5364236601224 72.4484506889507 -1.13924346035339 0.255103942240494 IL33 other 1 1 1 -1.23084669673081 -1.13924346035339 4.17826250870189e-29 137.493725908307 19.6234210805054 7.00661344136874 7.26074593839673e-12 -323.513285439327 47.8481575722117 -6.76124853817173 3.5423268843491e-11 RANBP6 other 5.67282700806456e-25 5.10130494615114e-07 8.64464411425514e-08 7.00661344136874 -6.76124853817173 6.38794920995168e-19 201.41163085126 23.2612908162787 8.65866096778725 5.61692509844968e-17 -49.8968144020438 57.0093897174189 -0.875238529115462 0.381836159642613 POLR1E essential 7.36722182383728e-15 1 7.43961729289661e-13 8.65866096778725 -0.875238529115462 9.0156000755409e-30 264.468383573914 26.6365827912168 9.92876547441817 2.07669825709628e-21 -205.701544389504 63.6168362021848 -3.233445054321 0.00129980958819093 PLAA other 1.23135065831738e-25 1 2.89159465318086e-17 9.92876547441817 -3.233445054321 0.00197493917979567 22.6481069254585 10.1281128667927 2.23616257276471 0.0257495422419825 -52.9305790458006 27.1744514995933 -1.94780671273504 0.0519568599034612 IL11RA other 1 1 1 2.23616257276471 -1.94780671273504 6.28626789942486e-31 343.329059759174 31.0455937318732 11.058865960959 8.86804546451772e-26 -155.447356909296 81.0468826265479 -1.91799304145447 0.0556360583724427 UBAP2 other 8.67693558157613e-27 1 1.27575702052552e-21 11.058865960959 -1.91799304145447 3.59527365720428e-47 178.109695502272 15.2770449509593 11.6586483887441 3.58585212492776e-28 -230.187797749934 37.1823666987264 -6.1907785379842 1.18571171966775e-09 APTX other 5.39830339629223e-43 1.65809926878338e-05 5.22781381293218e-24 11.6586483887441 -6.1907785379842 1.9480402342207e-17 165.460007195825 31.8631408845031 5.19283418403671 2.94610503456106e-07 -461.72257441456 83.299081758559 -5.54294914982203 4.67219425829312e-08 RNF38 other 2.16505191631289e-13 0.000625233035644785 0.00293137450938825 5.19283418403671 -5.54294914982203 0.284773788059937 -42.3919503015115 28.7770173777185 -1.47311827855846 0.141301780352839 -77.876179000164 77.0862344668114 -1.01024754340144 0.31282915719197 CCL21 other 1 1 1 -1.47311827855846 -1.01024754340144 0.618869672353604 -1.07557560574802 3.041325967573 -0.35365351074365 0.723737626777592 -7.90025531620359 8.07621609298967 -0.978212472925431 0.32841054404374 SIT1 other 1 1 1 -0.35365351074365 -0.978212472925431 0.143100459795347 11.9858476767793 11.4204404132854 1.04950835896277 0.294415423574603 -39.0286633779266 30.615083211126 -1.27481813813078 0.202923904828977 DNAJB5 other 1 1 1 1.04950835896277 -1.27481813813078 0.0012068188805238 4.67950239104933 2.28680992485846 2.04630141761299 0.0412186612192661 -14.0202246684111 6.084112108858 -2.30439946167309 0.0215852434993841 SPAG8 other 1 1 1 2.04630141761299 -2.30439946167309 1.74434829731737e-24 170.753163387092 22.6711936778357 7.53172355251975 2.14585505663722e-13 -320.255080153722 60.4472813243894 -5.2980890643382 1.71288406531878e-07 DCTN3 essential 2.23642895199059e-20 0.00224250781831535 2.6529206065206e-09 7.53172355251975 -5.2980890643382 4.69503287139356e-07 48.4837019621502 11.4247676993276 4.24373634879277 2.59050152843269e-05 -60.9919961105305 30.338376660628 -2.01039089180021 0.044890253925067 CD72 other 0.00322173155635026 1 0.225606778111203 4.24373634879277 -2.01039089180021 1.08619171945196e-11 35.3326694558427 21.7581269438082 1.62388378131498 0.104991824194702 -363.861715906106 58.1329891864893 -6.2591262035201 7.96570121918855e-10 TMEM8B other 9.824604102443e-08 1.11846410818626e-05 1 1.62388378131498 -6.2591262035201 2.20709409963806e-27 234.795611655025 35.6561083752763 6.58500387041202 1.08671945460655e-10 -612.062059580019 87.3627816314086 -7.00598181686068 7.38941717195678e-12 GRHPR other 2.9416150159976e-23 1.07508630434799e-07 1.25070542030668e-06 6.58500387041202 -7.00598181686068 0.00999404327912083 106.978994918346 42.0418255024858 2.54458491370743 0.0112227380322897 -88.6115918505044 105.731345372497 -0.838082515060423 0.402361439384864 ALDH1B1 other 1 1 1 2.54458491370743 -0.838082515060423 1.52056903129276e-08 73.6240751601549 23.0418399853626 3.19523420034706 0.00148019311338216 -244.3486345454 61.3033624445152 -3.98589285810476 7.66324725187582e-05 HINT2 other 0.000116308325203584 0.871157947593243 1 3.19523420034706 -3.98589285810476 1.81099542863699e-10 132.278769978996 21.9987620076245 6.0130097290543 3.37513395592242e-09 -75.241047750679 58.4204558579071 -1.28792298255398 0.198329557780356 ARHGEF39 other 1.54477910062735e-06 1 3.67736419311659e-05 6.0130097290543 -1.28792298255398 3.3780852108893e-12 94.0329325007469 47.5851092865859 1.97609995880065 0.0486577008527544 -642.415904951614 109.372955439646 -5.87362664169853 7.50347751957532e-09 DENND4C other 3.12810690528349e-08 0.000102985228956171 1 1.97609995880065 -5.87362664169853 1.01349370573267e-20 5622.36080132142 1130.37008842231 4.97391151704014 8.85962844804564e-07 -15909.3184340467 2598.1219580003 -6.12339170032329 1.77675681693943e-09 RPS6 essential 1.2173072899555e-16 2.47502224599663e-05 0.00855219934089846 4.97391151704014 -6.12339170032329 3.07748595312108e-16 248.000587129896 31.7734298139012 7.80528223054449 3.08912714018682e-14 -298.375473313747 155.566101118144 -1.91799801607901 0.0556373648955822 CNPY3 other 3.30614315943798e-12 1 3.89291802206343e-10 7.80528223054449 -1.91799801607901 8.02674815053803e-17 671.714832183386 82.2156198611123 8.17016077137314 2.18283840488439e-15 -513.342504569086 380.241992147527 -1.3500415923813 0.177566150090037 FOXP4 other 8.77163037890796e-13 1 2.81018616244817e-11 8.17016077137314 -1.3500415923813 3.64965775642642e-30 240.068546886252 21.2408085392279 11.3022320427628 9.3448025992959e-27 -80.9034625656064 72.3682686618658 -1.11794110957139 0.264084689223439 PPIL1 other 4.99930119475291e-26 1 1.35200604006613e-22 11.3022320427628 -1.11794110957139 4.85351031902207e-42 201.461839222771 14.3014577186531 14.086804519235 1.41099236862654e-38 -123.630221977923 69.3256230536453 -1.78332651813682 0.0750978564850375 KLC4 other 7.1710614963551e-38 1 2.12678879723079e-34 14.086804519235 -1.78332651813682 0.000523987294073751 78.9756890023822 54.0506831995007 1.46114136450197 0.144560427965509 -609.67560211986 196.079951088439 -3.10932147185653 0.00197443403794871 KIF13A other 1 1 1 1.46114136450197 -3.10932147185653 1.2506998640659e-16 33.2784335834218 6.92783837234837 4.80358111647763 2.01901701438556e-06 -138.527144467783 24.6768220976888 -5.613654137449 3.16355139268299e-08 ZSCAN9 other 1.3587603323212e-12 0.000425466026801936 0.0190675966838573 4.80358111647763 -5.613654137449 2.70100028694668e-08 231.858459153566 39.2098769412169 5.91326668791046 5.94070013619771e-09 125.950935140466 132.860075138941 0.947996868199495 0.34355352332391 PIM1 og 0.000203682431638649 1 6.41655021710715e-05 5.91326668791046 0.947996868199495 0.0156533882834227 54.8744138773787 19.323240446103 2.83981426564743 0.00468542955390062 16.0335038819336 63.7252137233156 0.251603767882968 0.801443781524956 GMPR other 1 1 1 2.83981426564743 0.251603767882968 1.00864958891805e-19 217.559467186315 27.1926978538231 8.00065768964249 7.52794728904285e-15 -246.926460707496 92.2936504131662 -2.67544364755423 0.00768824413344269 CMTR1 essential 1.18818921574547e-15 1 9.60340235663196e-11 8.00065768964249 -2.67544364755423 3.88097679119365e-09 324.940275519206 118.873274386832 2.73350151407287 0.00647278844727575 -1847.1177234177 394.664414195617 -4.68022364565702 3.63091996919733e-06 TFAP2A other 3.07916698613304e-05 0.0448854326592174 1 2.73350151407287 -4.68022364565702 2.99811573074612e-45 677.187033078197 46.5045720360876 14.5617302434844 9.31264184885319e-41 -654.84154441141 247.732478874061 -2.64334150850002 0.00844770198120878 YIPF3 other 4.48068395960007e-41 1 1.40946834382393e-36 14.5617302434844 -2.64334150850002 3.94614790947826e-31 283.025460773292 24.3368195236341 11.6295171806833 4.82471587013301e-28 -129.686848987725 84.2630491712472 -1.53907139918665 0.124374783464027 TMEM14B other 5.45831178839032e-27 1 7.03057596595782e-24 11.6295171806833 -1.53907139918665 4.64017579461886e-34 396.382688680568 31.8233830158997 12.4557055572164 1.80910148890304e-31 -309.244027919995 167.476954908214 -1.84648704706553 0.065370553397566 TMEM63B other 6.57373704823654e-30 1 2.67349018030091e-27 12.4557055572164 -1.84648704706553 2.96428114339151e-23 24.8766497449347 2.64532039596481 9.40402144968213 1.49600699907802e-19 -33.5085662965986 12.7242647948572 -2.63343830365287 0.008695224007795 FRS3 other 3.72847282215784e-19 1 2.0478839810379e-15 9.40402144968213 -2.63343830365287 5.97121486551555e-47 151.679664432456 10.1045690297377 15.010997894721 7.84168763822961e-43 -124.832143965219 53.4526667466001 -2.3353772891632 0.01988832950194 TJAP1 other 8.95861366273298e-43 1 1.19115235224708e-38 15.010997894721 -2.3353772891632 1.6433334390307e-43 96.23401632299 6.24310751714864 15.4144416155982 1.17922147207072e-44 91.9548695028692 32.8576001073943 2.79858751711375 0.00531711074874943 CAPN11 other 2.44150049036791e-39 1 1.79477508049164e-40 15.4144416155982 2.79858751711375 0.0790632055647388 13.1405024736179 6.7912298363988 1.9349223616596 0.0535226695029657 39.8683240964716 23.6716846514706 1.68421997350302 0.0927181028677177 KIAA0319 other 1 1 1 1.9349223616596 1.68421997350302 0.227932552145799 22.8692624540163 18.1113371081721 1.26270425631343 0.20727822691301 81.5221087889934 52.4103202514861 1.55545908511562 0.120463217586444 IRF4 other 1 1 1 1.26270425631343 1.55545908511562 1.37991481994602e-06 126.704433936676 46.0643266713683 2.75059776387505 0.00615088864507377 -461.354360475831 138.264836661418 -3.33674397349192 0.000906777557065567 SLC22A23 other 0.00910053823754398 1 1 2.75059776387505 -3.33674397349192 7.08412772516212e-13 247.367640226637 32.5275271949726 7.60487075282101 1.30083910173631e-13 139.487423469791 97.3221247557584 1.43325501595707 0.152372376060183 TUBB2A other 6.72850451335899e-09 1 1.61538199653615e-09 7.60487075282101 1.43325501595707 1.23457116922315e-13 166.410339101868 29.4577173831845 5.64912538664184 2.65358171053897e-08 -396.405043573787 108.249536908497 -3.66195602212015 0.000275809799724777 LRRC1 other 1.21086740277406e-09 1 0.000279262939217122 5.64912538664184 -3.66195602212015 0.577626998961443 -1.38813463971917 5.32116621672652 -0.260870377504037 0.794294763777068 -20.3113405880345 19.4176970535469 -1.04602211745416 0.296032175288357 GCM1 other 1 1 1 -0.260870377504037 -1.04602211745416 0.707531177266578 -2.50042965980464 3.12316008931644 -0.800608866755819 0.423728729027379 -0.476425080107136 9.24912122192159 -0.0515103077012276 0.958938938898573 FOXF2 other 1 1 1 -0.800608866755819 -0.0515103077012276 2.43166391978258e-29 135.801088260693 14.7722132146117 9.19300894779715 8.67151403677007e-19 -206.57147528616 44.1961095563605 -4.67397418821972 3.75173671110254e-06 BPHL other 3.30706293090431e-25 0.0463489553289608 1.17715803049154e-14 9.19300894779715 -4.67397418821972 2.09757714353402e-22 107.990939414747 18.6048752513285 5.80444308042515 1.11397433354127e-08 -354.501760526224 55.3936836288951 -6.39967839837437 3.43397072829888e-10 RIPK1 other 2.60330299284008e-18 4.85941197761575e-06 0.00011903929728222 5.80444308042515 -6.39967839837437 1.94195266461945e-07 228.324113895847 40.5266249374962 5.63392866413102 2.85818950039267e-08 253.639724790591 121.255367014386 2.09178142820266 0.0369316052073706 TUBB2B other 0.00137587346288288 1 0.000300281388911254 5.63392866413102 2.09178142820266 3.80407240546198e-11 340.372349610677 50.9303471716463 6.68309502119724 5.92720627555964e-11 -9.18713172114224 175.448771488371 -0.0523636138526691 0.958258659006725 UQCC2 other 3.35290941817419e-07 1 6.86903935274606e-07 6.68309502119724 -0.0523636138526691 3.27812484339512e-13 1219.02026892626 159.174705191047 7.65837931009923 8.71081970548277e-14 612.897073158936 544.976518919295 1.1246302398025 0.261243559363435 HMGA1 other 3.15847328661120e-09 1 1.08615210907665e-09 7.65837931009923 1.1246302398025 8.6959938187645e-17 385.036446448002 44.5154018351361 8.64951074403403 5.75922853087659e-17 133.967822453936 160.144011491977 0.836545938907292 0.40321314256481 TCF19 other 9.4899380544177e-13 1 7.62637042058678e-13 8.64951074403403 0.836545938907292 3.78679214247662e-14 649.384596005273 122.510546627429 5.30064238452985 1.68451114531636e-07 -1895.66330327382 444.667536127672 -4.26310254124228 2.37965318472288e-05 FLOT1 other 3.78414138797689e-10 0.280275552096661 0.00169731343002077 5.30064238452985 -4.26310254124228 0.0642682848598691 74.6434620552438 226.487802906166 0.329569456268551 0.741853101170981 -1744.96295293834 822.066149027416 -2.12265515981019 0.0342371488660255 IER3 other 1 1 1 0.329569456268551 -2.12265515981019 2.06902393093057e-32 733.410162458344 57.3227860953392 12.7943914177259 6.44117189668476e-33 369.838842972096 224.753731525226 1.64552926646554 0.100443686761624 MDC1 other 2.89394377219259e-28 1 9.56385203219754e-29 12.7943914177259 1.64552926646554 2.22747412213784e-10 35.3380989747771 6.72302888254401 5.25627653728078 2.11633610243973e-07 -58.3386831941723 23.5488948821885 -2.47734271548758 0.013539689553486 PGBD1 other 1.89223926675609e-06 1 0.00212289674435729 5.25627653728078 -2.47734271548758 6.20372309671475e-19 78.1549201609654 9.54316581397303 8.18962194354116 1.90341610021468e-15 -84.8014659032454 36.7624631998259 -2.30674058596941 0.02144686174651 ATAT1 other 7.15785570898948e-15 1 2.45388403639676e-11 8.18962194354116 -2.30674058596941 7.82619879857792e-10 112.720518102905 19.7859737714076 5.69699118199557 2.01138091904393e-08 -126.337596532479 71.9582102845756 -1.75570787590251 0.0797083999415353 TPMT other 6.44252685098934e-06 1 0.000212623076952133 5.69699118199557 -1.75570787590251 7.86402767328893e-05 214.180793643358 54.1723688338287 3.95369075146681 8.72770510726781e-05 -163.536448555057 199.658187574243 -0.819082104981274 0.413103599158056 RNF144B other 0.433386565074953 1 0.725185017362883 3.95369075146681 -0.819082104981274 5.74267907423326e-10 96.607742597102 14.6696223287012 6.58556440189252 1.07631218607801e-10 53.6545462398908 57.0425578274015 0.940605545814371 0.347327604526258 NRM other 4.76757216742845e-06 1 1.23905058861301e-06 6.58556440189252 0.940605545814371 9.46654754403274e-24 1003.79494449347 105.008563505617 9.55917223303203 4.037152359189e-20 -590.641038601688 357.801948132006 -1.65074852634335 0.0993660326897727 MTCH1 other 1.20016889763247e-19 1 5.55875508336734e-16 9.55917223303203 -1.65074852634335 9.97664176048578e-20 214.84463525016 27.0154603281146 7.95265498498923 1.07256405060879e-14 -279.037869472216 99.0293429588186 -2.81772918142307 0.00501331475673798 VARS2 essential 1.17534816580283e-15 1 1.36473049799463e-10 7.95265498498923 -2.81772918142307 5.94070025647771e-35 87.8388468797929 7.95464621329755 11.0424580206918 1.06028219215483e-25 -185.661516698255 38.1376453259546 -4.86819558762593 1.4809110265317e-06 TAF8 essential 8.47322077581416e-31 0.0186594789342995 1.52468579231864e-21 11.0424580206918 -4.86819558762593 1.81993314583545e-08 97.1436364575717 33.9392388871614 2.86228093625044 0.00436894232147148 -543.6956586854 123.765531505877 -4.3929489258452 1.34589540661053e-05 FAM8A1 other 0.000138642507049745 0.161292105528206 1 2.86228093625044 -4.3929489258452 0.000174761989850113 4.45094662158523 1.21912749475653 3.65092793061328 0.000286810311630285 -4.08114803617666 4.22106922956503 -0.966851717946643 0.334052583468947 C6orf52 other 0.919073304621745 1 1 3.65092793061328 -0.966851717946643 0.549201283587109 19.2505154125724 32.0909070097472 0.599874456858615 0.548839685654591 66.9801397633302 61.3049106036067 1.0925738102192 0.275064571235851 FGFBP1 other 1 1 1 0.599874456858615 1.0925738102192 0.00655159096143749 31.8637699301054 26.3086906479804 1.21114997156088 0.226363808141878 159.00915202696 50.2588452168865 3.16380432818888 0.00164420250456438 FGFBP2 other 1 1 1 1.21114997156088 3.16380432818888 7.54216465435971e-14 -170.357481099901 70.2168285266873 -2.42616313887138 0.0155840608523573 -1049.35946920711 133.971308857559 -7.83271790173228 2.52532012436569e-14 CPEB2 other 7.45467554436914e-10 3.76853522159092e-10 1 -2.42616313887138 -7.83271790173228 3.93751517831994e-06 100.181490090684 25.7115671547339 3.89635876676769 0.000109890135573954 -92.6429428593535 58.3342377822121 -1.58814011087676 0.112838889345736 FHDC1 other 0.0248496582903771 1 0.904945266451509 3.89635876676769 -1.58814011087676 0.000451451874839655 97.3294564688236 27.7819341360469 3.50333623253893 0.000497068975618043 190.033869472154 63.3945541866741 2.99763713003758 0.00284439566197475 TLR2 other 1 1 1 3.50333623253893 2.99763713003758 0.00107566069089623 14.4601478881959 3.90549197157052 3.70251635221799 0.000236882862652046 11.3882418633943 24.896128450535 0.457430234022975 0.647557787564448 MYO7A other 1 1 1 3.70251635221799 0.457430234022975 7.79363670435894e-31 218.832086191431 20.6472699201279 10.5985966686135 8.68098045939464e-24 -159.272487634033 63.1414176795628 -2.5224724671582 0.0119663428859218 FCHSD2 other 1.07443075606292e-26 1 1.23391456249835e-19 10.5985966686135 -2.5224724671582 1.16310898962202e-52 465.211926394859 27.3635123781389 17.0011773330139 7.46446000380016e-52 116.536594286089 126.190492261757 0.923497422011449 0.356177181232458 ARRB1 other 1.76746042062962e-48 1 1.14616783358351e-47 17.0011773330139 0.923497422011449 0.771892345002143 3.42068390117909 20.5314587131935 0.166606959055518 0.8677440806222 -66.6530414985454 105.022994539723 -0.634651885433863 0.525934600917737 SLCO2B1 other 1 1 1 0.166606959055518 -0.634651885433863 5.84219729540591e-117 555.712381224949 18.7439971864873 29.6474853093537 2.63632280456855e-112 -76.2855231588303 82.8178519938051 -0.921124145607357 0.357428943845071 THAP12 other 9.139533448933e-113 1 4.12373613090612e-108 29.6474853093537 -0.921124145607357 1.49246534907077e-17 71.5818691581013 16.6769267338672 4.29226981088392 2.11137313159958e-05 -198.438742789781 39.0524419429424 -5.08134019070331 5.24131496159989e-07 ANKRD42 other 1.66469585035354e-13 0.00673875864612898 0.185272992297863 4.29226981088392 -5.08134019070331 1.53591341101139e-16 472.042902441423 63.8235445799903 7.39606215148093 5.86607349804756e-13 -451.841435977284 209.267573396756 -2.15915647437946 0.031307314558445 IL18BP other 1.66324063278423e-12 1 7.16716859991451e-09 7.39606215148093 -2.15915647437946 1.81577115620326e-20 2038.73894093039 303.731114575776 6.7123150809818 5.1615647633059e-11 -4744.95006160052 995.974317937342 -4.76412892997812 2.48276171030594e-06 NUMA1 other 2.16966495454728e-16 0.0309774178594872 5.9899959078165e-07 6.7123150809818 -4.76412892997812 4.02618371904585e-53 252.420450966127 17.5596770772443 14.3750052951281 1.10531071714019e-39 -82.4083656666704 41.0959350388009 -2.00526805361319 0.045453100610934 CCDC90B other 6.12302019992493e-49 1 1.66946130716855e-35 14.3750052951281 -2.00526805361319 0.00184730384597453 153.151635849265 164.033745257913 0.933659324844788 0.350907226587167 -969.640746262715 376.87569795278 -2.57283966976349 0.0103592901231211 SYTL2 other 1 1 1 0.933659324844788 -2.57283966976349 2.89243721743007e-05 281.330416716417 142.391947821162 1.97574666981701 0.0487137402325841 -919.591388245019 335.234618680574 -2.74312775889427 0.00629652589714525 RAB30 other 0.168050602332687 1 1 1.97574666981701 -2.74312775889427 1.73263065601312e-25 329.25235707274 40.6994745507881 8.0898429453155 4.15475739709588e-15 -263.494262375883 92.5852838930775 -2.84596267674872 0.00460050288804792 CREBZF other 2.25449900960427e-21 1 5.32016684698127e-11 8.0898429453155 -2.84596267674872 0.152299969823523 -21.4331235651166 21.2226049602277 -1.00991954594092 0.313019397209577 -208.916461101261 112.720754760737 -1.85339835192472 0.0644106317826814 LRRC32 other 1 1 1 -1.00991954594092 -1.85339835192472 0.000292999381718453 200.855149953967 162.522827345568 1.23585808365796 0.217073633956578 -1087.02623033005 383.079796706495 -2.83759738747826 0.00472433371798138 PRCP other 1 1 1 1.23585808365796 -2.83759738747826 1.03981906096188e-112 155.454225887144 5.60564817381841 27.7317129200517 2.095951158321e-103 -93.482860803094 26.5194352912197 -3.52506981300787 0.000462042835928382 NARS2 other 1.62627701134438e-108 1 3.27618125557155e-99 27.7317129200517 -3.52506981300787 2.46152110857427e-44 125.870941899845 9.74965794063048 12.9102931268279 3.74485578833778e-33 -141.168638960579 33.1967290109597 -4.25248640954877 2.51936436870721e-05 RNF121 other 3.66618953911051e-40 0.296327637047341 5.56523018704878e-29 12.9102931268279 -4.25248640954877 1.30090031199424e-53 400.728277256792 22.556465945328 17.7655612465211 7.56165005630345e-55 397.134358315236 177.699288977747 2.23486745838904 0.0258769351926151 MRPL15 essential 1.98023045491763e-49 1 1.16411602616792e-50 17.7655612465211 2.23486745838904 0.0976619985126407 661.10507116799 317.158205640088 2.08446465962862 0.0376043921697703 2335.27485328999 3164.35421521979 0.737994135440928 0.460850282410206 PI15 other 1 1 1 2.08446465962862 0.737994135440928 1.70361731945857e-06 6.75853865598282 1.33822970269367 5.0503576795365 6.10499482142003e-07 -8.35269594287535 11.3511541456324 -0.735845521584185 0.462155227415603 TTPA other 0.011145064503898 1 0.00594992795295596 5.0503576795365 -0.735845521584185 1.24790552254071e-14 231.112541115331 28.0839096678298 8.2293578012776 1.51799998713367e-15 375.368119826763 238.221817528402 1.57570840371079 0.115700010050195 GGH other 1.27036782194645e-10 1 1.95913078339471e-11 8.2293578012776 1.57570840371079 0.116968276514309 5.492757247107 2.68757728262301 2.04375787912086 0.0414675912509871 14.9594323731896 24.6134460302099 0.607774805479444 0.543595220041056 SLCO5A1 other 1 1 1 2.04375787912086 0.607774805479444 0.589990851457013 104.062719078366 180.325417153697 0.5770829244203 0.564125280899166 -1268.78940636622 1638.2068841685 -0.774498885719318 0.438976693175113 SULF1 other 1 1 1 0.5770829244203 -0.774498885719318 1.05368984697143e-49 179.948394854547 10.7161338451903 16.7922869809351 1.06859417118813e-50 67.7099080863071 84.2689602234018 0.803497609402136 0.42206150304183 TGS1 essential 1.59223072775853e-45 1 1.63879602093412e-46 16.7922869809351 0.803497609402136 2.78000837606976e-08 347.611175920976 58.6451983648234 5.92735953860258 5.64874677626506e-09 801.795939828186 490.682229505072 1.6340431579047 0.102862090494084 SDCBP other 0.000209445831053096 1 6.10742501449778e-05 5.92735953860258 1.6340431579047 8.55374461147748e-12 46.6488836593274 15.7863191110706 2.95501968071921 0.00326242190835103 -165.964307497853 33.6070473089889 -4.938378131585 1.05070082929462e-06 NEK1 other 7.77963072413877e-08 0.0133291907204316 1 2.95501968071921 -4.938378131585 3.75594973901002e-06 413.439097536697 101.98814128394 4.05379578774419 5.78053539799445e-05 -300.262707251501 221.410999818516 -1.35613274632975 0.175623710524184 DDX60 other 0.0237638939987164 1 0.488455241130531 4.05379578774419 -1.35613274632975 4.37377510773089e-13 4.53102318805118 159.131343369265 0.0284734804100592 0.97729498057757 -1783.70597673112 285.579388096521 -6.24591987755172 8.51095760011618e-10 SORL1 other 4.18701491063078e-09 1.1941724608723e-05 1 0.0284734804100592 -6.24591987755172 0.697600391802967 38.1213745099086 48.4426767484177 0.78693782153881 0.43166032783513 17.1386674670111 89.4545009187551 0.191590890240134 0.8481340366074 TMPRSS4 other 1 1 1 0.78693782153881 0.191590890240134 8.73642394059844e-35 88.3038779080296 11.8062400881342 7.47942420693093 3.01252767137492e-13 -107.39705941507 21.7284915436301 -4.94268362805673 1.02767220791059e-06 BUD13 essential 1.24406676914122e-30 0.0130401326461774 3.71053033283248e-09 7.47942420693093 -4.94268362805673 0.0224075395179303 -13.5069929018287 7.00393176582661 -1.92848722023987 0.054317458162891 -38.7100207708203 14.2190412636707 -2.7224072321756 0.00668988236672184 TRPC6 other 1 1 1 -1.92848722023987 -2.7224072321756 0.510472119496329 498.237501021526 454.873791129045 1.09533130010601 0.273857105522146 275.782530118254 917.377086292919 0.300620687216725 0.763818819449522 MMP7 other 1 1 1 1.09533130010601 0.300620687216725 0.00604170119178355 47.4099013667468 15.5501260470495 3.0488435414157 0.00240919056932 27.0370848245417 31.3848683872778 0.861468797348899 0.38936014994417 MMP20 other 1 1 1 3.0488435414157 0.861468797348899 2.77658327617697e-08 1.89513114522902 4.05653268197208 0.467180050995596 0.640558819138303 -38.594098425081 8.23383614286233 -4.68725606818604 3.50712606136453e-06 C11orf70 other 0.000209271081525458 0.043390163631202 1 0.467180050995596 -4.68725606818604 1.05491389589985e-31 119.643436221425 19.3636876298752 6.17875264816984 1.27014711518114e-09 -229.096871471274 39.1886312322487 -5.84600340117896 8.70389775978888e-09 DCUN1D5 other 1.4663303153008e-27 0.000119234695411348 1.40808509188981e-05 6.17875264816984 -5.84600340117896 3.69654791704905e-25 408.777231814274 98.6290283514945 4.14459352025118 3.95054394795377e-05 -1248.21729680154 198.769629694396 -6.27971837911377 6.97049003552929e-10 YAP1 other 4.78481162382829e-21 9.79841784294352e-06 0.338798648976515 4.14459352025118 -6.27971837911377 0.0989966765023844 410.40052509243 192.97132310058 2.12674359328781 0.0338916501521025 334.170697816745 356.572994010408 0.937173323358837 0.349086042502449 TRIM29 other 1 1 1 2.12674359328781 0.937173323358837 1.14508952977924e-31 161.730921876091 21.484634432 7.52774837235318 2.16733640153541e-13 -167.289361436719 39.7394711740575 -4.20965243105519 2.99404711185252e-05 SLC37A4 other 1.59121641058123e-27 0.350303512086745 2.67904452593791e-09 7.52774837235318 -4.20965243105519 4.24983524527006e-09 44.8507445639822 12.3534525399774 3.63062426628015 0.00030949765813608 -46.4145357967754 22.5240916511753 -2.06066182448487 0.039811048066565 POU2F3 other 3.36331961310672e-05 1 1 3.63062426628015 -2.06066182448487 4.88870877177733e-17 404.25859767702 65.8126833056546 6.1425636727121 1.57073093548138e-09 -226.850346899511 124.117748313824 -1.82770272568862 0.0681427737117438 RDX other 5.37806851983224e-13 1 1.73283036802305e-05 6.1425636727121 -1.82770272568862 1.00044122715628e-11 169.923827057245 44.5477890851739 3.81441661969703 0.000152177656964168 -244.29061409145 82.0730074870311 -2.97650374430415 0.00304551631962434 PPP2R1B other 9.06799928294454e-08 1 1 3.81441661969703 -2.97650374430415 1.17192111985224e-33 59.1777361031471 9.65502354473492 6.12921717165754 1.69707217607639e-09 -116.997870613635 18.5793669388873 -6.29719360183117 6.25250098740073e-10 FDX1 other 1.65510419756732e-29 8.80227089006274e-06 1.870682659689e-05 6.12921717165754 -6.29719360183117 4.28015437432206e-36 29.0974154340934 14.1879200754428 2.05085842599697 0.0407601106546101 -263.979711760366 26.1392382089004 -10.0989825966115 4.31831934713108e-22 C11orf1 other 6.15229389765053e-32 6.69080399644489e-18 1 2.05085842599697 -10.0989825966115 0.0586870112362507 60.5293649713454 55.6062041681016 1.08853617823581 0.276838710635936 246.915242560628 104.378827247557 2.36556827731946 0.0183508704845216 FXYD6 other 1 1 1 1.08853617823581 2.36556827731946 0.667409130510941 1.12286457647334 8.48125242703827 0.132393722051432 0.894721924106988 -10.3123282809017 15.6608521951976 -0.658478105301569 0.510510054338637 ARHGAP20 other 1 1 1 0.132393722051432 -0.658478105301569 0.600445561262781 44.5534241117105 63.3135788889152 0.7036946085433 0.481924057497037 -26.6720678110427 127.756626623368 -0.208772480269639 0.834704002955546 MMP13 other 1 1 1 0.7036946085433 -0.208772480269639 1.30322398612741e-11 198.158591022509 38.4487066144686 5.15384283298466 3.5723626135463e-07 -88.528197785077 72.172358564007 -1.22662193042458 0.220493414863564 TMPRSS13 other 1.17446545629802e-07 1 0.00353628175114948 5.15384283298466 -1.22662193042458 1.19784884214751e-06 18.3335852130288 26.6785470863614 0.687203285609257 0.492249656347495 -205.547049114355 52.2494947837107 -3.93395285380704 9.44624145795077e-05 CASP1 other 0.00793814427691154 1 1 0.687203285609257 -3.93395285380704 6.18780612219533e-10 1.68980633586748 0.726883996100832 2.32472629048373 0.0204557741508221 -5.42861391336151 1.42228925952415 -3.81681424999141 0.000150805195244649 CASP5 other 5.12659737223883e-06 1 1 2.32472629048373 -3.81681424999141 6.27554413825277e-13 28.104804422711 10.0594469808316 2.793871718422 0.00539307865891924 -81.6010974381342 19.2820223490105 -4.23197815878072 2.72188838405478e-05 ALKBH8 other 5.97055269313369e-09 0.319440820752669 1 2.793871718422 -4.23197815878072 4.5450314875588e-37 112.468370588775 10.1242185401592 11.1088446128116 5.85474914301235e-26 -109.174203964729 22.144619813707 -4.93005546643673 1.09614946420542e-06 MAP2K5 other 6.56166195858864e-33 0.0138958867577321 8.43200971576638e-22 11.1088446128116 -4.93005546643673 5.26124048191113e-20 3.03395121356314 79.1123396197527 0.0383499113810259 0.96942294888994 -1189.64706430631 136.857879924925 -8.69257265243992 4.30684281523163e-17 SQOR other 6.23193935082374e-16 6.55716818619016e-13 1 0.0383499113810259 -8.69257265243992 3.90420753523029e-12 52.2748095244191 32.3511316055774 1.61585721828063 0.106724777260026 -316.350055086387 56.3135427278247 -5.61765500379499 3.14064120771892e-08 CTDSPL2 other 3.60319313426403e-08 0.000422447648850272 1 1.61585721828063 -5.61765500379499 5.19364808145613e-13 180.557153978377 89.547847655494 2.0163204220498 0.044260173247774 -1020.16007921877 162.733641509669 -6.26889480106766 7.43738720628803e-10 SLTM other 4.95733709374987e-09 1.04502727635553e-05 1 2.0163204220498 -6.26889480106766 0.00443228162588072 1148.10900699473 896.770562750815 1.28027062292605 0.201001691784063 -2939.22690314683 1514.99810703645 -1.94008618855397 0.0528914075556878 THBS1 other 1 1 1 1.28027062292605 -1.94008618855397 1.41235933713035e-17 23.1453042243636 21.1736657381439 1.09311748426574 0.274840693665223 -262.505653873516 35.702416079539 -7.35260194404484 7.45614835206595e-13 MAPKBP1 other 1.57633425617118e-13 1.0967994225889e-08 1 1.09311748426574 -7.35260194404484 0.000993453932894052 269.054648531962 78.6985416023269 3.41880094667481 0.000676109201982838 404.117855129674 134.788638789153 2.9981596279923 0.00284029205172501 NUSAP1 other 1 1 1 3.41880094667481 2.9981596279923 1.24981906534439e-41 74.0404557104821 12.7938586759931 5.78718724237707 1.2096460144183e-08 -202.746725419037 21.9123094365818 -9.25264066783204 4.98266642394313e-19 NDUFAF1 other 1.8428582118503e-37 7.64540336089833e-15 0.000129105519118865 5.78718724237707 -9.25264066783204 1.25104258024448e-10 189.651445317157 37.4428765576635 5.06508748132868 5.60222422169469e-07 485.866909446914 81.8153171042232 5.93858126624353 5.13519558582224e-09 KIF23 essential 1.07301922107569e-06 7.07681303682162e-05 0.00547337306459571 5.06508748132868 5.93858126624353 0.465875166185217 -79.2667833061143 139.19692579083 -0.569457858754924 0.569281386063158 -366.838084134882 301.770022150555 -1.21562135801503 0.224658409382817 ITGA11 other 1 1 1 -0.569457858754924 -1.21562135801503 0.00780887931750245 71.4471170365773 26.3312278605955 2.71339860848257 0.00687116938490548 123.198718796381 46.2568110744481 2.66336385787812 0.00796603589897344 KNL1 other 1 1 1 2.71339860848257 2.66336385787812 3.551858289823e-08 52.5970177026938 18.7237490966121 2.80910716284971 0.00515486857512394 -96.089926150128 31.4179697539388 -3.0584384319767 0.00233955920983883 HAUS2 other 0.000265714518661658 1 1 2.80910716284971 -3.0584384319767 5.699824654076e-38 270.533115399765 61.7162448765892 4.38349928678805 1.40307866785154e-05 -1014.42634259113 105.0674308608 -9.6550028327532 1.85547054817554e-20 RTF1 essential 8.27158553799509e-34 2.8613211323415e-16 0.124916093798823 4.38349928678805 -9.6550028327532 3.24443068424767e-23 413.503911001269 41.3199224690125 10.0073738354996 9.9324523104431e-22 -86.4629572970853 91.0197465580742 -0.949936256325637 0.342572759654867 PARP6 other 4.07857381316775e-19 1 1.38676899158407e-17 10.0073738354996 -0.949936256325637 0.000615202070061723 1818.7940845952 900.020569175543 2.02083613073565 0.0437870002235755 -5080.66595885003 1966.60820527555 -2.5834662670586 0.0100415364334688 RPLP1 essential 1 1 1 2.02083613073565 -2.5834662670586 0.0150131048524974 -25.2119785456658 21.4786202693136 -1.17381741608822 0.240982747890365 -135.479651870082 46.9322950011282 -2.8867041738919 0.00404798238593109 PAQR5 other 1 1 1 -1.17381741608822 -2.8867041738919 0.0305264090780247 10.3005193833572 16.5199825776606 0.623518780055265 0.533207915986551 -82.7433822875967 35.8454935362401 -2.30833430160314 0.0213588470859904 LRRC49 other 1 1 1 0.623518780055265 -2.30833430160314 1.89462489898414e-27 176.595383796728 36.4270454742821 4.84791949216433 1.64411094674739e-06 -430.652404549687 62.6630667051599 -6.87250763796764 1.78743856938799e-11 TUBGCP4 essential 2.52761907773474e-23 2.58552989061973e-07 0.0156108334393665 4.84791949216433 -6.87250763796764 2.10237765502589e-36 208.090499733696 33.337243265336 6.24198282015922 8.70256666090988e-10 -467.541303550294 58.5039035252099 -7.99162577842051 8.01361371941843e-15 RMDN3 other 3.02448049452025e-32 1.20172151336399e-10 9.71119413690933e-06 6.24198282015922 -7.99162577842051 0.0109356495490946 1.94912609091305 7.31268362182823 0.266540464720086 0.78992474722737 -31.1049880726571 12.4826834104136 -2.49185107480238 0.0130067988692054 ITPKA other 1 1 1 0.266540464720086 -2.49185107480238 0.0876069730989051 91.5000735311642 54.1801103288973 1.68881297907513 0.0918347197169555 -102.711229340646 116.74691935936 -0.879776784726027 0.379373040792229 UACA other 1 1 1 1.68881297907513 -0.879776784726027 1.48328359720866e-07 50.7827133864191 9.39850358454757 5.40327648221711 9.83653877671707e-08 69.0389864097066 21.6972137457539 3.18192866691085 0.00154726238037713 SMAD6 other 0.00106069610036391 1 0.00100519589759272 5.40327648221711 3.18192866691085 0.173076197390039 30.6962305566904 16.4068157540167 1.8709438209651 0.0619036484741433 29.6285694907138 29.1321193416374 1.01704133308169 0.309597806508322 PLCB2 other 1 1 1 1.8709438209651 1.01704133308169 1.16956944772566e-25 56.5928977691949 40.6199061553341 1.39323063802212 0.164140770331663 -633.509100115446 69.9553393082738 -9.055907760289 2.66957763625563e-18 TMEM62 other 1.52500160288949e-21 4.08685640334374e-14 1 1.39323063802212 -9.055907760289 2.7324759445381e-09 208.868429053437 101.201063222788 2.06389559953165 0.0395030170540841 -907.99840365313 184.419459597993 -4.92354985548939 1.12987457852521e-06 ADAM10 other 2.18488776525266e-05 0.0143143810353359 1 2.06389559953165 -4.92354985548939 0.998764025507879 -1.57865312413429 32.2180356674518 -0.048999049489821 0.960938477714091 -1.73332738022624 57.3518575028499 -0.0302226894767987 0.975900808918776 DUOX1 other 1 1 1 -0.048999049489821 -0.0302226894767987 0.408992907485987 23.8938659095053 20.7565364050383 1.15114898956386 0.250179454737025 -13.4512131339686 40.8560765793483 -0.329234088541135 0.742106178181477 STRA6 other 1 1 1 1.15114898956386 -0.329234088541135 0.001472651738728 -42.9981738986394 41.4966557522572 -1.03618407602161 0.300586142895582 -256.917397770932 71.9795813749063 -3.56930941891389 0.000390248699336334 SEMA6D other 1 1 1 -1.03618407602161 -3.56930941891389 8.16380983555321e-17 91.9564440336722 46.2897797006305 1.98653881328408 0.047476655084196 -613.678884014075 85.6619971977347 -7.1639572282854 2.57165470665317e-12 RSL24D1 essential 8.91814586435833e-13 3.76387382865758e-08 1 1.98653881328408 -7.1639572282854 0.00959502394960346 -0.420409024391245 27.7071432218384 -0.0151733082340977 0.987900142913462 -126.06037215065 47.2634128909577 -2.66718724780808 0.00790411360636864 SPTBN5 other 1 1 1 -0.0151733082340977 -2.66718724780808 3.55775902620716e-06 69.2025155967813 22.0561637004129 3.13755903051652 0.00179584755804063 -79.0835691084185 38.7066099915622 -2.0431541053494 0.041518506017764 GCHFR other 0.0225526344671272 1 1 3.13755903051652 -2.0431541053494 0.00396538912463613 -21.1735752627612 46.3013461801832 -0.457299344610057 0.647641538195445 -465.938297180304 140.765145642429 -3.31004024507515 0.000995685588387749 BCAR3 other 1 1 1 -0.457299344610057 -3.31004024507515 0.000189365603836049 65.8973747644925 20.3851826365127 3.23261144820264 0.00130150517884858 -39.9263954678197 38.8738084282493 -1.02707702389163 0.30484403673082 TTLL7 other 0.991897032893222 1 1 3.23261144820264 -1.02707702389163 3.35468665529527e-35 746.137109269828 61.8173428695245 12.0700288080106 7.6725210667979e-30 -506.544000016932 186.961516502535 -2.70934901199341 0.00695725630422753 FNBP1L other 4.79250535575482e-31 1 1.12701661950194e-25 12.0700288080106 -2.70934901199341 9.16394139423711e-11 23.4053601317713 23.1162889970993 1.01250508395652 0.311753449437162 -284.900531889756 48.2233987087624 -5.90793140919758 6.16182645743674e-09 KYAT3 other 7.91764536462087e-07 8.47312756162126e-05 1 1.01250508395652 -5.90793140919758 1.45632091330804e-32 87.0176836274066 13.0574343798156 6.66422522956881 6.54653296217406e-11 -202.638142268817 26.7050513005886 -7.58800797601728 1.42188369974989e-13 GTF2B essential 2.04059686372723e-28 2.10765820813927e-09 7.57892121030891e-07 6.66422522956881 -7.58800797601728 7.10880541171133e-18 304.50221423318 46.6518293754326 6.52712269400381 1.54475615663269e-10 -341.780021152296 93.8565365239445 -3.64151537879412 0.000297090973640218 RABGGTB essential 8.00167137142227e-14 1 1.7689002749601e-06 6.52712269400381 -3.64151537879412 2.89878509855631e-06 1005.01949458484 196.959045398426 5.10268260364379 4.6427665699536e-07 697.578075262318 397.413931680126 1.75529346017942 0.0797750836250331 IFI44L other 0.0185580222009575 1 0.00456430381492139 5.10268260364379 1.75529346017942 0.0690072779458666 -9.98238154490275 5.11533859932996 -1.95146056337508 0.0515198726914508 -19.6912832315352 10.293990912447 -1.91289106421548 0.0562915924176596 GIPC2 other 1 1 1 -1.95146056337508 -1.91289106421548 2.3488205271367e-06 366.751084109942 145.481234218892 2.5209511458923 0.0119912119307084 -897.795409599839 291.116539122893 -3.08397252971203 0.00214722839438169 ARHGAP29 other 0.015171031784776 1 1 2.5209511458923 -3.08397252971203 5.88640437016057e-07 577.587204122086 107.59259853572 5.36828008601662 1.18060845449312e-07 295.262993269637 216.098163398899 1.36633735625326 0.172399679357552 IFI44 other 0.00400923001651636 1 0.00120008849399226 5.36828008601662 1.36633735625326 0.0613382839706114 -62.3655165328775 30.2271006135332 -2.06323184384265 0.0395653790885134 -111.908419766277 60.9281155185847 -1.83672872226193 0.0667963614013726 SLC44A5 other 1 1 1 -2.06323184384265 -1.83672872226193 0.0162535333030654 660.785103249951 275.982166407359 2.39430363146947 0.0169901027142744 -277.953568341792 536.356608388294 -0.51822530755614 0.604512168845 CLCA2 other 1 1 1 2.39430363146947 -0.51822530755614 0.821457913744402 -3.14005285950047 6.43030596452986 -0.488320909894689 0.625519687844408 -6.9057083848624 12.2115227619192 -0.565507555404753 0.571962175013491 DNASE2B other 1 1 1 -0.488320909894689 -0.565507555404753 2.09411227287875e-13 126.257134449198 27.3860624209308 4.61026972437997 5.03113049264435e-06 -207.972603427981 52.3176632904164 -3.97518907282845 7.99434179385391e-05 DBT other 2.03526771801086e-09 0.907698809339133 0.0463115561847912 4.61026972437997 -3.97518907282845 6.07172734110211e-28 216.228324871561 22.8692201552825 9.45499336677709 1.00297207090696e-19 -121.888951067999 43.4874636640965 -2.80285261080036 0.00524866439438576 RTCA other 8.14097201894971e-24 1 1.37507470921344e-15 9.45499336677709 -2.80285261080036 1.48979810642363e-08 80.4194980309799 17.7355656568719 4.53436330066079 7.12781875596607e-06 -160.354213981654 54.3566560005424 -2.95003824333958 0.00331566095251989 IFT172 other 0.000113999351103536 1 0.0649201732293389 4.53436330066079 -2.95003824333958 2.48012906747217e-12 378.638002315776 55.5834698092091 6.81206127676907 2.55636530167273e-11 -234.019358693741 167.036724487357 -1.40100543405623 0.161782630072701 SELENOI other 2.3075120843761e-08 1 2.99784958927161e-07 6.81206127676907 -1.40100543405623 1.12228658912516e-08 174.711152045324 28.7662067572391 6.0734859315908 2.36791844443654e-09 40.9119783387566 88.3117197755541 0.463267824958399 0.643359751543076 CGREF1 other 8.652829602155e-05 1 2.59429144772468e-05 6.0734859315908 0.463267824958399 1.90058268241573e-07 213.566479890636 65.3394426475496 3.26856904860123 0.00114932694637406 -722.996397260651 196.338782015042 -3.6823921888507 0.000254163886138935 HADHB other 0.00134694294702803 1 1 3.26856904860123 -3.6823921888507 4.08991037222302e-08 58.5550827764833 9.98116291326374 5.86655916603373 7.77872223171997e-09 17.4098356831478 30.6419845226372 0.568169325661205 0.570157049437081 KHK other 0.000304371129900837 1 8.36212639909897e-05 5.86655916603373 0.568169325661205 3.80260913972215e-06 218.525343558548 46.9336992654572 4.65604346085247 4.05879174898647e-06 -92.5782068895184 135.500769195518 -0.683230120678759 0.494753390254572 ADCY3 other 0.0240477001996029 1 0.0375641176368697 4.65604346085247 -0.683230120678759 6.59124794111006e-13 163.057927696756 23.1372121696207 7.04743192487347 5.56440050280694e-12 -140.100207508079 76.5630854238862 -1.82986626952694 0.0678190260530695 PPM1B other 6.26761766720156e-09 1 6.64556352050233e-08 7.04743192487347 -1.82986626952694 4.96668194891298e-25 270.174994360339 24.9844940211403 10.8137068588115 8.05225130047961e-25 -105.610976684004 88.579998484692 -1.19226663457502 0.233676528573689 PNPT1 essential 6.41844308258025e-21 1 1.15195507104661e-20 10.8137068588115 -1.19226663457502 4.75482765594768e-06 13.7930399676461 12.0974012948976 1.14016553071309 0.254720928712887 -180.266692952949 39.129074976412 -4.60697558175393 5.09811655518225e-06 DYNC2LI1 other 0.0297462018156087 0.0626303618804139 1 1.14016553071309 -4.60697558175393 5.80607740594429e-08 28.9280833230403 5.84325290903393 4.95068137104184 9.89098981245635e-07 -39.031832113035 18.2095021836972 -2.14348704974372 0.0325184057088729 THUMPD2 other 0.000428140147914332 1 0.00951809949652675 4.95068137104184 -2.14348704974372 0.383267635779025 409.179099694551 295.201423158976 1.38610137890221 0.166285919559055 230.266380468747 927.322707021683 0.248313104731688 0.803986213088471 CYP1B1 other 1 1 1 1.38610137890221 0.248313104731688 4.45464531733614e-20 644.815413130041 73.1318256917629 8.81716553676396 1.58805637065831e-17 -707.097319927854 251.055806817412 -2.81649458298374 0.00503135340863666 RAB1A other 5.28320934636066e-16 1 2.11957883791765e-13 8.81716553676396 -2.81649458298374 7.78990966728331e-16 1360.17443791334 168.120820945064 8.09045798293954 3.88459953776605e-15 -853.324620134901 572.701266157945 -1.48999953476541 0.136802837330976 ACTR2 essential 8.26587314795432e-12 1 4.97889122755475e-11 8.09045798293954 -1.48999953476541 4.47401991250589e-22 300.782158333089 31.2134283496959 9.63630636671217 2.20774097305865e-20 -142.331277143088 95.8390028489938 -1.48510807616966 0.13809979384506 PREB essential 5.52138797402352e-18 1 3.04756563921016e-16 9.63630636671217 -1.48510807616966 1.14653284545382e-08 811.874682499954 136.840188900074 5.9330134591733 5.31784397121421e-09 -70.9818196238416 417.335178171953 -0.1700834804647 0.86500818631172 SLC5A6 other 8.83518210706713e-05 1 5.75337539245666e-05 5.9330134591733 -0.1700834804647 1.85079778613185e-05 214.957387523547 58.1292612476906 3.69792051214286 0.0002394726509425 -445.064356530993 193.151548595529 -2.30422359938198 0.0215866520813603 PREPL other 0.109844848606925 1 1 3.69792051214286 -2.30422359938198 0.0299950912053927 44.6561317373343 26.3668518146126 1.69364670652814 0.0909059309769303 -151.811518109107 86.6807016056999 -1.7513877402571 0.0804437227151255 SLC3A1 other 1 1 1 1.69364670652814 -1.7513877402571 0.0133259193156626 -258.776276765642 87.7059011627932 -2.95050017541375 0.00331078691353586 -191.703456449737 267.693203067123 -0.716131206370854 0.474221054028241 EMILIN1 other 1 1 1 -2.95050017541375 -0.716131206370854 4.13779866978816e-14 252.715807385298 32.6965192416088 7.72913488184694 5.24688337345739e-14 -145.479631418915 114.901303863638 -1.2661268978424 0.206008572321887 FBXO11 other 4.12869551271463e-10 1 6.57696830862884e-10 7.72913488184694 -1.2661268978424 1.49954932898158e-05 74.954221493191 16.4867820775477 4.54632208642257 6.73607872423702e-06 116.049130137537 54.7821771906979 2.11837382317917 0.0345969863654065 SIX3 other 0.0898230048059965 1 0.0614801905161113 4.54632208642257 2.11837382317917 3.57339296894036e-12 283.381811593987 50.0895323767514 5.65750563336296 2.49397115789999e-08 -512.496514418685 152.763044884909 -3.3548461593234 0.000849877448117259 ATRAID other 3.30450218781212e-08 1 0.000262689982061606 5.65750563336296 -3.3548461593234 5.41549060159664e-19 247.435137672195 26.948839933231 9.18166192998457 8.9216754431196e-19 -8.01037844593482 77.8031264747808 -0.10295702510787 0.918035160054716 CENPO other 6.26193178262619e-15 1 1.21067135763133e-14 9.18166192998457 -0.10295702510787 9.53335022622869e-13 1016.74282209913 136.646270571638 7.44069207191496 3.97071150086315e-13 -190.474864134285 449.325890499636 -0.423912505737168 0.671798432663443 LRPPRC essential 9.01473597392185e-09 1 4.87126886925891e-09 7.44069207191496 -0.423912505737168 1.42197822857847e-11 198.145246666227 27.4631810826667 7.21494156375373 1.83665121268945e-12 106.031810319852 83.1107244350603 1.27578974964539 0.202578356376426 DTNB other 1.27892721878348e-07 1 2.22142964174788e-08 7.21494156375373 1.27578974964539 6.82780421869475e-24 447.059455909722 57.7092975247834 7.74674922559455 4.65674633245501e-14 -534.787707920151 119.085724403395 -4.49077931548363 8.67305698620798e-06 ACTR1A essential 8.67267691858608e-20 0.105143469843799 5.84654502039727e-10 7.74674922559455 -4.49077931548363 1.03288055731587e-09 39.3089702815964 6.32258261557482 6.21723315797632 1.00973443150208e-09 53.3561161126656 13.046932871652 4.08955243638882 4.97679448279891e-05 MFSD13A other 8.44793007828647e-06 0.574421619204651 1.12454123636387e-05 6.21723315797632 4.08955243638882 0.190405394709366 3.53741763403025 6.29819600437893 0.561655691815689 0.574581514827555 -16.8621062817109 12.3514910126354 -1.3651879165407 0.172757248860185 CYP2C8 other 1 1 1 0.561655691815689 -1.3651879165407 5.92565917304157e-09 -135.620173337911 269.766953283853 -0.502730863387885 0.615357338523523 -3092.14697103509 517.20952513273 -5.97851899622607 4.08284076785761e-09 MYOF other 4.64808705533381e-05 5.64003623671851e-05 1 -0.502730863387885 -5.97851899622607 0.0317224116719898 -39.1505968731857 49.9624901907836 -0.78359979103699 0.433614134258911 190.131482922157 96.4946807777272 1.97038304484492 0.0492983862818008 LOXL4 other 1 1 1 -0.78359979103699 1.97038304484492 0.213676890192262 8.43672034205729 4.86691891748136 1.73348282252117 0.0835838788075247 8.71577318555834 9.90654653579638 0.879799348245598 0.379361557464454 STAMBPL1 other 1 1 1 1.73348282252117 0.879799348245598 0.0392691944214096 -4.77727481433681 4.84533342514201 -0.985953781745535 0.324598166158335 -24.7653004707343 9.70874591429952 -2.55082383341176 0.0110221000107669 CH25H other 1 1 1 -0.985953781745535 -2.55082383341176 6.5396402915142e-13 186.916441927748 35.9767240535678 5.19548254725577 2.91962655692277e-07 -268.567834190986 75.5407247397336 -3.55527214117026 0.000411434497210386 ATAD1 other 6.2205058452883e-09 1 0.00290561234944954 5.19548254725577 -3.55527214117026 3.32224095989617e-07 265.579791335149 59.2129301548294 4.48516549748025 8.8929736644973e-06 530.343560813156 112.568871825181 4.71128076718029 3.12966243257738e-06 KIF11 essential 0.00231128303579976 0.0388391107882853 0.0804903046373651 4.48516549748025 4.71128076718029 5.89925797211022e-145 131.127220788891 3.63948512162316 36.0290580691838 2.60465561209302e-146 98.7700394749228 13.3802704141744 7.38176706580536 5.87539063229683e-13 CUZD1 other 9.23882791012182e-141 8.65210024512031e-09 4.07915115409888e-142 36.0290580691838 7.38176706580536 1.25928838151434e-16 431.341130640166 50.1704331105793 8.59751658291366 8.72870893202144e-17 -70.2610155258982 190.320715152072 -0.369171666204372 0.7121436835309 TACC2 other 1.36796496883903e-12 1 1.15227686611615e-12 8.59751658291366 -0.369171666204372 3.1330302995823e-07 144.073231108418 96.4072328074921 1.4944234671283 0.135645847303805 -763.821953000849 179.902800767441 -4.24574798025649 2.56279427469481e-05 DUSP5 other 0.00218215560365907 0.301256466990375 1 1.4944234671283 -4.24574798025649 7.9685882672029e-07 17.6824106254631 22.9773073138076 0.769559739266635 0.441893277895151 -226.78569136643 48.0169521202156 -4.72303387350884 2.95695189055626e-06 CALHM2 other 0.0053724222097482 0.0367460411439427 1 0.769559739266635 -4.72303387350884 7.63881456510564e-21 201.735797481541 37.3950149895598 5.39472433793282 1.02472182211599e-07 -479.712038285039 77.8041710065927 -6.16563395096634 1.3677168765397e-09 ARL3 other 9.20400766949578e-17 1.91056370483831e-05 0.00104552367510494 5.39472433793282 -6.16563395096634 9.22507627272268e-12 215.246750415165 41.3220445952654 5.20900532690068 2.69817728119993e-07 530.927858180774 79.2031450069894 6.70336838434789 5.10600632232072e-11 CEP55 essential 8.37913677851401e-08 7.33375688074925e-07 0.00268900347844385 5.20900532690068 6.70336838434789 3.33300832495338e-05 113.476884411516 25.5647344841015 4.43880551476435 1.09839215154002e-05 138.106325692825 49.8487444181385 2.77050760866451 0.00579076208525848 KIF20B other 0.192347910433059 1 0.0986356152082942 4.43880551476435 2.77050760866451 0.000745056852059568 -64.3822844447208 25.6266802628605 -2.51231465739349 0.0122814153502385 -181.44605995314 49.721669531952 -3.64923506513674 0.000288273459189798 ENTPD1 other 1 1 1 -2.51231465739349 -3.64923506513674 4.21168698110176e-12 26.8800647316224 34.9056997489988 0.770076661545608 0.441588691621703 -433.116509368297 66.3587366938099 -6.5268950397107 1.5401736532225e-10 EXOC6 other 3.88359656527393e-08 2.19336129955416e-06 1 0.770076661545608 -6.5268950397107 0.391667935280149 -19.7262375771251 46.7506194924434 -0.42194601464722 0.673230811035441 -123.573189371555 90.5030373885036 -1.36540378021889 0.172689469096581 PLCE1 other 1 1 1 -0.42194601464722 -1.36540378021889 0.14599234818147 226.13170124173 142.756066986732 1.58404266813226 0.11376514167507 -130.530586841162 273.624637525151 -0.477042520811613 0.633523422083365 RBP4 other 1 1 1 1.58404266813226 -0.477042520811613 1.57776168598089e-17 67.6680603175421 7.69669027698473 8.79183881413139 1.91016405361365e-17 -41.7932495470555 28.2291698653645 -1.48049870918568 0.139315937598983 DBR1 essential 1.7584153990257e-13 1 2.54701274908843e-13 8.79183881413139 -1.48049870918568 9.88039586291077e-15 297.332808406465 42.3116571649867 7.0272078270787 6.29523355725435e-12 -444.963278979543 145.132744225143 -3.06590550158188 0.00227729552777129 DNAJC13 other 1.00928243739634e-10 1 7.50769554038153e-08 7.0272078270787 -3.06590550158188 0.000565480947057677 27.3176205704656 7.4907049077574 3.64686914073672 0.000290875497309583 -49.0999665949849 35.4280534865235 -1.3859064149167 0.166341246755568 GPR87 other 1 1 1 3.64686914073672 -1.3859064149167 8.23282670566756e-32 683.297550079924 71.3893866774648 9.57141645111817 3.84886189694776e-20 -969.158296237039 190.024593718908 -5.1001729685088 4.7157694246148e-07 ANXA7 other 1.14551550782658e-27 0.00607438259584633 5.30142237685585e-16 9.57141645111817 -5.1001729685088 9.1116249661111e-34 277.36998706753 23.2518391497846 11.9289482987026 2.86512941807245e-29 -102.19113761578 61.5339346120121 -1.66072815366225 0.0973506892598225 FAM149B1 other 1.28838377020811e-29 1 4.19655505865072e-25 11.9289482987026 -1.66072815366225 7.29264803592965e-26 181.578834602581 17.0494875026645 10.6501051468089 3.56279522129653e-24 -21.7376534359533 44.2513315869699 -0.491231623012993 0.623461851873634 ASCC1 other 9.54097142540676e-22 1 5.07698319034755e-20 10.6501051468089 -0.491231623012993 0.0950331431304735 -5.57832720651787 9.72624795185678 -0.573533312550699 0.566526014432718 -53.7257337773834 24.7636093220327 -2.16954374779215 0.0304834255999998 ZNF365 other 1 1 1 -0.573533312550699 -2.16954374779215 0.16859616804695 -3.72103428293051 7.75799150376381 -0.479638870592375 0.631677328090268 -41.8613205696586 22.1856223565931 -1.8868670843132 0.0597114134933847 ADAMTS14 other 1 1 1 -0.479638870592375 -1.8868670843132 8.20663010069226e-22 3312.56940623831 415.892410834836 7.96496718848241 9.96429344958763e-15 -7047.53124542629 1459.44623972822 -4.82890774156827 1.79376539440062e-06 RPS24 essential 1.007610043763e-17 0.0225099619343333 1.2684545561325e-10 7.96496718848241 -4.82890774156827 1.924047368527e-09 49.2007927733249 7.7648403544292 6.33635600057893 4.95113906569305e-10 62.7300581207067 20.1926817493785 3.10657390134114 0.00199179722744162 TET1 og 1.55424546429611e-05 1 5.57696304359665e-06 6.33635600057893 3.10657390134114 1.42084194085478e-15 92.3248649246142 10.8144185200706 8.53720102965016 1.39531219670135e-16 72.3066695974854 28.2495841443342 2.55956580557266 0.0107510054959913 DNA2 other 1.49472572177922e-11 1 1.83357975768525e-12 8.53720102965016 2.55956580557266 0.713672936078346 -25.06567867969 39.6383949050157 -0.632358569002458 0.527419261699397 -71.5108232361183 103.567134996305 -0.690477951704173 0.490189242339561 MYPN other 1 1 1 -0.632358569002458 -0.690477951704173 0.0269456715094593 102.171659551177 42.4766565931186 2.40536020831097 0.0164918434333957 -61.5595819458348 106.171066749949 -0.579815045946731 0.562281177878592 AOX1 other 1 1 1 2.40536020831097 -0.579815045946731 1.43863878697475e-15 439.377792077658 72.3469395772149 6.07320495718711 2.35588325099955e-09 -660.795618370298 165.19268672337 -4.00015056039895 7.2061431817668e-05 ATIC other 1.51301641226135e-11 0.820995892698691 2.58157686644531e-05 6.07320495718711 -4.00015056039895 1.41952934243787e-14 75.826524980285 14.1545306249654 5.35704976656336 1.24981441346599e-07 -145.731449323977 32.5293991253444 -4.47999204542436 9.10014012901583e-06 SMARCAL1 other 1.44110618844293e-10 0.110148096121608 0.00126878378725295 5.35704976656336 -4.47999204542436 0.00320610100569411 62.478981414457 19.9176070439332 3.13687187806468 0.00180015843460974 -17.7086464563698 45.3605190904875 -0.390397791106484 0.696395524745594 BARD1 other 1 1 1 3.13687187806468 -0.390397791106484 0.820708007770608 -0.494881877814333 4.34107272710111 -0.113999904844904 0.909280477127088 -6.95209697926227 11.0790425824417 -0.627499797706357 0.530598392039312 STAT4 other 1 1 1 -0.113999904844904 -0.627499797706357 1.33732808567498e-08 -11.5995260173323 6.8021892947731 -1.70526363126141 0.0887214430073227 -102.869192886432 16.7973451397084 -6.12413402420675 1.75866081889019e-09 CARF other 0.000102519571047844 2.45069385112348e-05 1 -1.70526363126141 -6.12413402420675 5.87302473375052e-16 157.250967451844 22.5654363456929 6.96866504342418 9.39264472165033e-12 -188.578634138574 58.7765165748687 -3.20840099290955 0.00141423523297748 ASNSD1 other 6.25359673649755e-12 1 1.11547048714319e-07 6.96866504342418 -3.20840099290955 1.12496378149885e-17 207.162292179544 24.6532444328094 8.40304377560321 3.82880547928789e-16 -76.1689227152401 63.5380298366085 -1.19879264294333 0.231131485509455 METTL5 other 1.25883447149721e-13 1 4.99544250882691e-12 8.40304377560321 -1.19879264294333 7.9916697619263e-25 545.995513209545 52.8472324844719 10.3315819493476 5.77621832271287e-23 -142.980052488842 136.201506602185 -1.04976850884959 0.294291543142113 SSB other 1.0305258158004e-20 1 8.15428740617376e-19 10.3315819493476 -1.04976850884959 0.000249015565909555 144.218890533448 39.0569072924292 3.69253226973767 0.000244649445529985 -74.4594963300178 99.2549368799603 -0.75018430992576 0.453471040038534 NAB1 other 1 1 1 3.69253226973767 -0.75018430992576 0.0161768374154653 -3.53980371685829 1.8580370166488 -1.90513089090268 0.0572900647185003 -11.8547505904694 4.55335533537349 -2.60351976011488 0.00947912615232589 CDK15 other 1 1 1 -1.90513089090268 -2.60351976011488 1.83664415905655e-12 202.922793895442 45.8923867082615 4.42170931717769 1.18283759279922e-05 -538.53049408571 117.392859714169 -4.58742120599956 5.57546354121609e-06 PPIG other 1.7179969463815e-08 0.0683384566246856 0.105934934811098 4.42170931717769 -4.58742120599956 2.39969807280672e-05 49.0116111612537 11.7648797892979 4.16592536762151 3.6070957706218e-05 -24.2274503287026 30.0937755770104 -0.805065162618239 0.421134443692934 FASTKD1 other 0.140502322162833 1 0.310462732977419 4.16592536762151 -0.805065162618239 0.000136648014667837 6.16839189073102 3.36545929672934 1.83285291749797 0.0673687935926024 -25.6607078429689 8.01452552575699 -3.20177504713171 0.00144533704355112 MDH1B other 0.730110342370254 1 1 1.83285291749797 -3.20177504713171 0.579538701749645 6.1114637902871 21.9898722979424 0.277921749952998 0.781179000271084 -50.1730142672538 55.4066850990064 -0.905540805727675 0.365583549228892 HECW2 other 1 1 1 0.277921749952998 -0.905540805727675 0.00356941056644731 375.675610955441 155.633088211631 2.41385437552069 0.0161134089395579 -587.331924207601 368.109504742528 -1.59553588440594 0.111172131731431 IDH1 other 1 1 1 2.41385437552069 -1.59553588440594 7.3212423312485e-09 178.2570403058 60.5243636045009 2.94521131144192 0.00336594362578969 -655.623723916994 149.769928197518 -4.37753914826179 1.44063559086117e-05 OLA1 other 5.71642601223883e-05 0.172227984887453 1 2.94521131144192 -4.37753914826179 1.46789800377026e-16 35.8301626459304 22.1898571197108 1.61470902911327 0.106955681803401 -423.303399629236 54.1141801058431 -7.82241177453465 2.72604647443928e-14 CIR1 other 1.59046748708508e-12 4.06671613056852e-10 1 1.61470902911327 -7.82241177453465 0.0205253600101335 -507.263814990161 488.719508373879 -1.03794468258078 0.299759488738559 -3663.7725889845 1317.22906665172 -2.78142403758027 0.0056008506394087 SSFA2 other 1 1 1 -1.03794468258078 -2.78142403758027 0.253325266838054 8.00501096714568 4.94764522200152 1.61794360912308 0.106256520913936 1.51846789656797 12.065772357109 0.12584920812577 0.89989795649699 CHRNA1 other 1 1 1 1.61794360912308 0.12584920812577 1.29034603901168e-07 85.1926871461237 20.0534814511637 4.24827416394474 2.53573921882508e-05 -119.721291396863 49.0049133856504 -2.44304668910853 0.0148819837089965 FAM117B other 0.000926726525218185 1 0.221167174665923 4.24827416394474 -2.44304668910853 1.10862871006659e-12 148.132534532163 20.5143350280011 7.22092791845164 1.76818627301224e-12 -12.4389653148548 50.6581559030898 -0.245547140299595 0.806126278520106 WDR12 essential 1.04576946220582e-08 1 2.13968220897211e-08 7.22092791845164 -0.245547140299595 5.85346187692782e-12 321.401215553349 96.3206777238087 3.33678316171051 0.000906091882510033 -1291.55594444635 239.543322092618 -5.39174264247276 1.04624525501454e-07 ABI2 other 5.36820988733051e-08 0.00138376397428223 1 3.33678316171051 -5.39174264247276 0.0153841734651575 274.53357133666 198.188018247328 1.38521780360131 0.166567503592016 -1074.41090396007 507.862623914921 -2.11555419392324 0.0348477063777208 ITGAV other 1 1 1 1.38521780360131 -2.11555419392324 0.00144536631264821 78.7932694399876 895.728311640103 0.0879655900299891 0.929936757549026 -8159.98044017618 2333.11641526235 -3.49745961530112 0.000508557492472315 SLC40A1 other 1 1 1 0.0879655900299891 -3.49745961530112 4.17632833573134e-08 65.6143153782699 16.2780616567905 4.0308432761648 6.35061266109119e-05 -205.389993567779 54.9577836276691 -3.73723210818081 0.000205733980412951 SLC35A5 other 0.00031059353832834 1 0.534658079937267 4.0308432761648 -3.73723210818081 4.77279455567667e-11 52.1587741680005 11.7431979754708 4.44161584237529 1.08236861232594e-05 -176.36708106464 38.5774131712979 -4.57177054048454 5.99423041097522e-06 DIRC2 other 4.18239986913947e-07 0.0733334148478708 0.0972508198174855 4.44161584237529 -4.57177054048454 0.000208170343752748 19.207173743385 12.7727854874078 1.50375763863885 0.133229471062439 -161.899954749946 44.4671830545293 -3.64088623629274 0.000297900226759278 SENP7 other 1 1 1 1.50375763863885 -3.64088623629274 1.12133871010154e-09 110.346174075206 20.0472325450567 5.50430957625696 5.72641258808931e-08 -166.339211197716 63.7256236923314 -2.61024061531049 0.0092981145983477 COX17 essential 9.15236655184879e-06 1 0.000593084551748409 5.50430957625696 -2.61024061531049 1.34256525428392e-07 549.726091372885 102.384287258623 5.36924274312009 1.17216992642088e-07 -320.514169557828 336.316768801213 -0.953012752531752 0.341006084114915 PARP9 other 0.000962753543846998 1 0.00119162794719946 5.36924274312009 -0.953012752531752 0.00015850095518475 2.74558791067594 7.90411085261504 0.347362019823845 0.728455207189949 -54.1918439977984 14.5678093280461 -3.71997208210763 0.000220176682791648 MNS1 other 0.839738060568805 1 1 0.347362019823845 -3.71997208210763 6.67232383722358e-32 251.928556349847 38.5493840198638 6.53521613263735 1.47803354569895e-10 -601.58532112924 78.9640154581055 -7.6184742840036 1.16740636067806e-13 USP8 essential 9.28987647856639e-28 1.7323849794186e-09 1.69367864001642e-06 6.53521613263735 -7.6184742840036 2.49228696860127e-11 22.8121417119946 60.7749054102577 0.375354623063622 0.707545792106035 -667.73661114126 106.978800693414 -6.24176572192934 8.82360276651639e-10 SECISBP2L other 2.21639080117711e-07 1.23759852403159e-05 1 0.375354623063622 -6.24176572192934 6.94984503372561e-16 274.853510225662 54.2321326754778 5.06809333629511 5.53105176999822e-07 -557.816731505529 119.088950332681 -4.68403432851863 3.56510156506312e-06 TMOD3 other 7.3856003173402e-12 0.0440967412582657 0.00540770931552726 5.06809333629511 -4.68403432851863 8.86519701463031e-30 272.222815582444 41.1887346194205 6.60915704494818 9.30423954038715e-11 -583.425128965642 83.4739169656292 -6.9893105556059 8.19310565213944e-12 SPPL2A other 1.21107456416865e-25 1.19086790653847e-07 1.07296490379745e-06 6.60915704494818 -6.9893105556059 1.30235879396199e-07 27.3954080204227 77.6536467379422 0.352789716532876 0.724383246277205 -906.929866686877 169.140061791755 -5.36200505710755 1.220230111582e-07 GLCE other 0.000934833142305915 0.00160911744814318 1 0.352789716532876 -5.36200505710755 0.192629481080741 -6.75336696258158 10.3230321183803 -0.654203811935944 0.51326057199641 22.0082170108239 18.3377049699258 1.20016201847057 0.23060561175357 SHF other 1 1 1 -0.654203811935944 1.20016201847057 5.53806292511617e-21 150.276291020802 29.4143649385194 5.1089422238047 4.50108567793972e-07 -447.817455887178 64.923485066744 -6.89761887284399 1.48424544105213e-11 APH1B other 6.68998001354034e-17 2.14992952136402e-07 0.00442951841566048 5.1089422238047 -6.89761887284399 3.94211323024873e-52 409.307619502146 25.9103548582556 15.7970673015206 1.73039958155942e-46 -144.428744969152 58.5273692484081 -2.46771291489546 0.0139068680885678 INTS14 other 5.98531051748665e-48 1 2.64110888133414e-42 15.7970673015206 -2.46771291489546 0.000714664191155433 -919.878913883494 310.127723158581 -2.96612925963127 0.00314943355791945 -2197.18520445378 704.342903305968 -3.11948227793717 0.00190858481293488 CILP other 1 1 1 -2.96612925963127 -3.11948227793717 1.48972550873658e-26 80.3092400536822 8.79299752805528 9.13331771076296 1.33488959471222e-18 -87.2019360169377 19.9395360495921 -4.37331820560195 1.4692658834286e-05 PARP16 other 1.96584178132879e-22 0.17562135104622 1.80717353332141e-14 9.13331771076296 -4.37331820560195 4.09014537008589e-13 61.104924940899 10.6394590316206 5.74323607612894 1.55484470831192e-08 -68.3956403410893 20.4491846461958 -3.34466344377271 0.000881250849511051 PPCDC other 3.92122236630135e-09 1 0.000165171153363976 5.74323607612894 -3.34466344377271 0.000258529565160591 29.1965809625112 11.9406521215694 2.44514124230879 0.0147973806255795 88.58830919028 23.0200266681333 3.84831479421843 0.000133127407173612 SEMA7A other 1 1 1 2.44514124230879 3.84831479421843 2.41762722846957e-14 151.900824762371 28.7438814186381 5.28463162472816 1.82952809718891e-07 -245.873790215242 55.4144706726237 -4.43699609922848 1.10578236615491e-05 UBL7 other 2.43382533090031e-10 0.133158312532374 0.0018401393601526 5.28463162472816 -4.43699609922848 0.0209878783920191 -19.7299886857761 11.5879239281984 -1.70263360443407 0.0892110684846955 -77.241524149876 28.7565957818572 -2.68604548103737 0.00745247068287457 ARHGAP24 other 1 1 1 -1.70263360443407 -2.68604548103737 0.240370874798817 55.3533815760359 35.7637379950606 1.54775156846527 0.122260460147689 -8.72961050173407 87.8348623545662 -0.0993866247150811 0.920867714102992 FAM13A other 1 1 1 1.54775156846527 -0.0993866247150811 0.00786947694845842 229.264681834069 73.3697885348828 3.12478318954221 0.00187353699592315 176.417048920823 180.685578037549 0.976375927934663 0.329309014331832 HERC6 other 1 1 1 3.12478318954221 0.976375927934663 2.9043753847472e-06 177.731078878541 35.013835870572 5.07602421898362 5.2881694513256e-07 197.677430625274 86.2275236159136 2.29250965742442 0.0222543080762316 HERC5 other 0.0185909068377668 1 0.00517817552673803 5.07602421898362 2.29250965742442 0.138263561082934 285.054861662495 151.573100320476 1.88064281234463 0.0605614441538619 54.2339800196124 311.632510911762 0.174031842380427 0.861906023665285 PCDH10 other 1 1 1 1.88064281234463 0.174031842380427 0.625096125586176 18.877786345013 35.178109171008 0.53663448064375 0.59174031571439 -39.2147641870604 76.848980923598 -0.510283463954416 0.610060630072108 NDST4 other 1 1 1 0.53663448064375 -0.510283463954416 3.13256491220702e-16 55.0849048239364 6.55067629080291 8.40904089571257 3.60607297995407e-16 21.4076224335475 14.2005719485067 1.50751832469668 0.132255152953654 ZGRF1 other 3.36406145921912e-12 1 4.70844948992603e-12 8.40904089571257 1.50751832469668 1.83674144543121e-23 98.6845515369352 32.2624053788924 3.05880948360717 0.00233098856105214 -557.063522952916 69.9385206162732 -7.96504584375351 9.62956352534401e-15 AP1AR other 2.31815137827873e-19 1.44270120736704e-10 1 3.05880948360717 -7.96504584375351 2.88197022247224e-30 136.075670351875 19.804308904641 6.87101332377151 1.76874565804187e-11 -323.755724741707 46.5899906284159 -6.94904034911403 1.06727798968123e-11 COPS4 essential 3.95146937203169e-26 1.54915400202231e-07 2.08287488691011e-07 6.87101332377151 -6.94904034911403 3.99874813364629e-07 498.182615496264 107.222786490556 4.64623828387579 4.2521823050149e-06 -236.583593729394 250.903723431904 -0.942925798363463 0.346140516064035 HNRNPD other 0.00276233521072285 1 0.0392944166806427 4.64623828387579 -0.942925798363463 0.406948137029728 2.66415070030232 3.66572457876905 0.726773286714559 0.467682720139214 -6.28511336176141 8.32827852543035 -0.754671369667796 0.450778250790351 PRKG2 other 1 1 1 0.726773286714559 -0.754671369667796 6.57205285141154e-09 46.0956425633389 24.2761343848007 1.89880488518796 0.058126870481548 344.737681671785 55.4156982895907 6.22093905359197 9.96288303961527e-10 RASGEF1B other 5.1452601773701e-05 1.39560065618931e-05 1 1.89880488518796 6.22093905359197 9.074969189848e-09 590.714896457898 155.391715305336 3.80145682346821 0.00016030082113353 -1128.90607550314 366.419176724518 -3.08091428400286 0.00216921287251864 SEC31A other 7.03673110980814e-05 1 1 3.80145682346821 -3.08091428400286 0.270070722462156 15.9889451029609 10.0518777249089 1.59064261827815 0.112276340004824 21.0564950568166 23.7118094395251 0.888017218193293 0.374927583665489 GPAT3 other 1 1 1 1.59064261827815 0.888017218193293 0.412082559114289 16.492684792935 42.7905281027281 0.385428400260465 0.700072104366007 -108.646631231638 102.105166361766 -1.06406595379019 0.28777528012291 FGF2 other 1 1 1 0.385428400260465 -1.06406595379019 3.35066871745176e-16 59.376348809717 7.34177947664898 8.08746013123487 4.00928504116622e-15 -5.41625785724371 17.8979291874862 -0.302619247204901 0.762296146401744 BBS7 other 3.59493246695399e-12 1 5.13669599474216e-11 8.08746013123487 -0.302619247204901 5.73910511395694e-14 254.410172648216 80.589168530652 3.15687799349178 0.00168352898630727 -1144.66724432038 195.961092643602 -5.84129853981884 8.94701415116854e-09 KIAA1109 other 5.69720964662505e-10 0.000122511464771951 1 3.15687799349178 -5.84129853981884 1.59872882071043e-05 -527.185831401276 663.745736038449 -0.794258708986625 0.427393741106572 -7075.60672140936 1522.44300978998 -4.64753470304641 4.22657787431661e-06 BMPR1B ts 0.0954920724610338 0.0521306115018211 1 -0.794258708986625 -4.64753470304641 1.82789121704604e-06 125.181982881967 75.6649087750728 1.65442587466922 0.0986199586415942 -667.051548012276 170.955401632986 -3.90190389797879 0.00010744688850182 RAP1GDS1 og 0.0119251623000084 1 1 1.65442587466922 -3.90190389797879 4.05740289729906e-12 91.2135234381811 21.9434370854835 4.15675644079125 3.75741471366674e-05 -177.814058044733 45.5742299791502 -3.90163603699023 0.000107702784252812 LARP1B other 3.74335991304811e-08 1 0.322874646345383 4.15675644079125 -3.90163603699023 0.0433186249606125 -32.7326012429159 24.7930736757412 -1.32023167724231 0.187313916012868 -140.067464297314 56.7219644859874 -2.46936906305345 0.0138416859297952 MMRN1 other 1 1 1 -1.32023167724231 -2.46936906305345 0.0138533572511318 -92.7345565166868 76.2643812541944 -1.21596156674498 0.224529861969982 -485.94333872883 165.471362070393 -2.93672169400591 0.00345822222626717 PDE5A other 1 1 1 -1.21596156674498 -2.93672169400591 0.00107117707291656 2.69650151351622 4.12102253223427 0.654328262566978 0.513176866105936 -31.1729010624017 9.87537423131905 -3.15662984836959 0.00168443818533702 PRDM5 other 1 1 1 0.654328262566978 -3.15662984836959 0.000297871263403512 82.9723908690718 23.5688451800422 3.52042665795656 0.000467186851362564 -47.2961276949452 69.0427317471061 -0.68502688839405 0.493620340726657 NAAA other 1 1 1 3.52042665795656 -0.68502688839405 1.85985093500666e-21 178.129597743063 18.297724126632 9.73506849869915 9.509910847268e-21 21.6653363289116 53.6969505332015 0.403474240413628 0.686758504542474 NUP54 essential 2.26641434939911e-17 1 1.31674225591273e-16 9.73506849869915 0.403474240413628 0.0386119285527527 433.653980812264 207.603983379353 2.08885192737296 0.0371869677863157 1282.80532712224 610.343698186694 2.10177532910293 0.0360338722444714 CXCL9 other 1 1 1 2.08885192737296 2.10177532910293 0.00663138378318989 -33.7650183684183 82.1887683213491 -0.41082278099607 0.681365457206617 -597.587769160497 194.308138926049 -3.07546442708676 0.00220814171112823 BMP2K other 1 1 1 -0.41082278099607 -3.07546442708676 3.51780747786586e-31 957.105707620155 90.3711958207438 10.5908270763466 6.18201049862859e-24 -817.654230607572 271.725451466213 -3.00911904348879 0.00274281353382828 G3BP2 other 4.86864554936635e-27 1 8.79638273849862e-20 10.5908270763466 -3.00911904348879 0.131065160858259 118.513105639398 110.509621449948 1.07242341512385 0.284010703209141 -346.347475270562 286.575893149746 -1.20857156358781 0.227358403936496 SEPT11 other 1 1 1 1.07242341512385 -1.20857156358781 0.992185935470867 -1.51217533998524 33.9873992379229 -0.0444922345896347 0.964528428523227 7.87169703877552 85.2026428886143 0.0923879444569133 0.92642395498081 FRAS1 other 1 1 1 -0.0444922345896347 0.0923879444569133 2.29011759612202e-22 1547.6700169501 196.707880744783 7.86785974761279 1.96349682833797e-14 -2206.85653366039 580.298132437877 -3.80297024977354 0.000159193579505545 SCARB2 other 2.84089087798937e-18 1 2.4824490400677e-10 7.86785974761279 -3.80297024977354 8.93649918199523e-16 -135.145031695404 128.099135669921 -1.05500346265909 0.291897281774773 -2772.37556742496 332.762941911804 -8.33138315071081 6.67979835941634e-16 CCNG2 other 9.46464628365114e-12 1.00965152202578e-11 1 -1.05500346265909 -8.33138315071081 1.20597360409723e-13 145.808173283253 37.4451760849113 3.89391073906598 0.000111070571337912 -463.716151706064 93.6656095450852 -4.95076212025138 9.91309661101274e-07 CNOT6L other 1.18313324202818e-09 0.0125926066249695 0.913666519825665 3.89391073906598 -4.95076212025138 1.07531798890728e-26 697.076732906942 68.1792538404355 10.2241766173968 1.52418508192355e-22 -320.807387756944 199.01751355116 -1.61195556126007 0.107558052190196 USO1 other 1.42146284953653e-22 1 2.14285180667632e-18 10.2241766173968 -1.61195556126007 0.0788872819145178 3.85126355579091 2.32389199715386 1.65724722169002 0.0980513996054446 -6.29062388375041 7.02296168610593 -0.895722369694204 0.370800902723613 CDKL2 other 1 1 1 1.65724722169002 -0.895722369694204 4.27106172254007e-11 211.922052375024 129.091746184828 1.64163905623837 0.101253593290724 -2087.89699495065 356.529808235649 -5.85616390753688 8.28321633592993e-09 SHROOM3 other 3.75554457262948e-07 0.000113562895965599 1 1.64163905623837 -5.85616390753688 0.182287545788601 49.4155689181794 52.487993492134 0.941464240304499 0.346885651747261 232.479708895514 127.299461917811 1.82624266743258 0.068362659847019 ANXA3 other 1 1 1 0.941464240304499 1.82624266743258 1.76690712184242e-18 199.658850013168 40.0331246071693 4.98734115741274 8.28207271306988e-07 -462.17670686535 86.6467664540959 -5.33403294524792 1.41902241013778e-07 PPA2 essential 2.01780793314404e-14 0.00186700778501828 0.00801456176443772 4.98734115741274 -5.33403294524792 2.26349710207623e-16 274.786884780702 31.5597081941873 8.70688927444877 3.85603152427476e-17 318.199059968997 71.4015409188504 4.45647328999017 1.01465998596831e-05 CENPE essential 2.44231337314026e-12 0.122459313706516 5.11965305477959e-13 8.70688927444877 4.45647328999017 2.513259806954e-11 18.703082805044 27.7734900414093 0.673414928306035 0.500974155736551 -376.490092317268 60.1969861341801 -6.2543013611689 8.17747390208477e-10 GSTCD other 2.23403664240141e-07 1.1477084621576e-05 1 0.673414928306035 -6.2543013611689 1.93002302750343e-30 49.1071560437948 15.2088027424429 3.22886402535502 0.00131906674036362 -321.900351601355 32.9639554279748 -9.76522226844705 7.72682292104461e-21 INTS12 essential 2.65069362597321e-26 1.19325326369692e-16 1 3.22886402535502 -9.76522226844705 0.00690878213391697 50.6789600939641 16.6629808448447 3.04141021140545 0.00246801843448788 75.1923971145935 36.6156735429682 2.05355766640086 0.0404951418877208 ENPEP other 1 1 1 3.04141021140545 2.05355766640086 6.9941270890459e-19 61.80047842706 19.3954329232437 3.18634178838037 0.00152381591881575 -292.616086613251 42.4781184638744 -6.88863106924351 1.5673928058017e-11 CASP6 other 8.05723440658087e-15 2.26942804352028e-07 1 3.18634178838037 -6.88863106924351 0.00230425349691784 -87.6187241600287 66.5827974070692 -1.31593636152521 0.188753759454916 -506.818871307887 144.666837393816 -3.5033521188288 0.000497539740991766 LEF1 other 1 1 1 -1.31593636152521 -3.5033521188288 6.09890209473387e-08 312.587930124314 70.4745164958785 4.43547463206213 1.1137315596323e-05 -262.651775498363 153.122515354614 -1.71530473418682 0.0868630265132255 HADH other 0.000448635238088624 1 0.0999908194237875 4.43547463206213 -1.71530473418682 0.0895443121092028 16.4161356116397 36.0687677609419 0.455134362239466 0.649193830505527 -141.266752331989 79.1148115856945 -1.78559171791711 0.0747213239368575 EGF other 1 1 1 0.455134362239466 -1.78559171791711 1.20333743425653e-16 1316.81275543806 151.691050473223 8.68088625749553 4.65386650849761e-17 1686.86273430836 329.584598237038 5.11814794541814 4.29657593023789e-07 PAPSS1 other 1.3082684585237e-12 0.00554172363482083 6.17335392352208e-13 8.68088625749553 5.11814794541814 3.25999026233842e-22 212.781599164543 37.8565368888526 5.62073598515556 3.04850956715772e-08 -471.317483212668 82.5078695112677 -5.71239429650165 1.84038311263885e-08 SEC24B other 4.03293395353886e-18 0.000249500738580449 0.000319788653594845 5.62073598515556 -5.71239429650165 0.0343903093609553 249.419217411668 130.753713462674 1.90754978047235 0.056977672456986 -253.529214023408 287.907630717963 -0.880592200321941 0.378928878253618 PPP3CA other 1 1 1 1.90754978047235 -0.880592200321941 0.090674541747628 726.09665672611 357.761365157883 2.02955580853645 0.0428897565106549 11.2105028062249 811.183086088677 0.0138199415131782 0.988978718459821 SLC39A8 other 1 1 1 2.02955580853645 0.0138199415131782 3.29637269232478e-05 57.5697863394612 47.4952047618276 1.21211786807014 0.225992478874221 510.082563895511 111.997863439325 4.55439548783757 6.48676272619269e-06 FBN2 other 0.190365522981756 0.0791968861240866 1 1.21211786807014 4.55439548783757 9.69474464282997e-10 211.737648758012 36.0231126750323 5.87782767880489 7.26105675826898e-09 -136.593348630936 164.889430659821 -0.82839359736003 0.407811586473827 MAPK8IP3 other 7.9370874390849e-06 1 7.81797981162821e-05 5.87782767880489 -0.82839359736003 1.61877254074022e-13 178.125450196516 37.6603851745349 4.72978301658372 2.86655673461431e-06 -370.333694374669 84.3236358958354 -4.39181364086507 1.35090412128606e-05 RGS3 other 1.58024575427061e-09 0.161878840853709 0.0268252379225207 4.72978301658372 -4.39181364086507 2.05704167569125e-43 612.264389816852 71.0503908752317 8.61732612973266 7.3782167514598e-17 -1095.71555159563 157.268652704517 -6.96715799844933 9.32791077806884e-12 GUCD1 other 3.05532400090422e-39 1.35459920319116e-07 9.754740367105e-13 8.61732612973266 -6.96715799844933 9.31280425973979e-55 229.720200957264 25.426415661734 9.03470642552998 2.90131610384086e-18 -485.792598852601 52.4710131626631 -9.2583041487424 4.835172982361e-19 RNF185 other 1.41936449722694e-50 7.41957294143295e-15 3.91155437119824e-14 9.03470642552998 -9.2583041487424 0.165222659280115 29.0920320505689 15.3394590923747 1.89654875542715 0.0584150654790865 24.9773866923213 30.5637419734536 0.817222796672462 0.414157562332247 KIAA1644 other 1 1 1 1.89654875542715 0.817222796672462 0.745287520786511 -5.92681152751998 12.8132134877237 -0.462554653693896 0.643867560230091 7.85188539049946 25.4976820877112 0.307945065888312 0.758241356522862 PARVG other 1 1 1 -0.462554653693896 0.307945065888312 1.11811771733758e-09 186.350679998267 39.4462711239814 4.72416465963432 2.97867631529545e-06 -461.881545718666 151.666770024585 -3.04537075355265 0.00244199234953968 B4GALNT3 other 9.12719492662663e-06 1 0.0278416875190666 4.72416465963432 -3.04537075355265 0.00481343345632872 73.8236435574525 33.5382860401451 2.20117520224755 0.0281483398996014 -171.234526123532 106.127923219713 -1.61347288186381 0.107229258977125 ERP27 other 1 1 1 2.20117520224755 -1.61347288186381 2.16246310601369e-23 727.70431924948 71.121312591056 10.2318741420556 1.41529269463136e-22 35.3007925967036 237.770374117089 0.148465900042365 0.882030621698624 ETV6 other 2.72578474513025e-19 1 1.99075070426847e-18 10.2318741420556 0.148465900042365 9.34850171175292e-12 188.728215867767 31.0440017566257 6.07937782465455 2.27251867235736e-09 -206.057657279786 104.904005904172 -1.96424965380269 0.0500098418695569 GABARAPL1 other 8.48843955427165e-08 1 2.49181672423984e-05 6.07937782465455 -1.96424965380269 7.33394300913663e-09 228.978694145704 37.4683017850545 6.11126427504756 1.96484152369753e-09 -9.26111185286001 126.241536740008 -0.0733602591667834 0.941548203397949 KIF21A other 5.72487591293205e-05 1 2.16014677115306e-05 6.11126427504756 -0.0733602591667834 7.87185851293371e-05 -1.72633914351972 9.87377794133407 -0.174840790807421 0.86127481012354 143.075662386825 33.452722112299 4.27695127190331 2.26656238905056e-05 CPNE8 other 0.433660685477518 0.267567690027418 1 -0.174840790807421 4.27695127190331 1.11733486487668e-41 121.779685002465 8.4488300302328 14.4137927460602 9.86724187230807e-40 -78.7571238141911 38.4813296942294 -2.04663207950429 0.0412083279701583 YARS2 essential 1.64784545872012e-37 1 1.49064422964958e-35 14.4137927460602 -2.04663207950429 5.32815912782376e-20 134.717643505152 13.8800919448297 9.70581780298178 1.49900756490047e-20 0.343448909230506 64.2166273294615 0.00534828631638425 0.995734796602208 FGD4 other 6.3096060391689e-16 1 2.07162845469245e-16 9.70581780298178 0.00534828631638425 1.44651578785083e-24 41.7833237793822 3.85294144826332 10.8445260174446 9.51504450785085e-25 -10.1943939601558 17.8518710720679 -0.571054648501611 0.568219684897854 ALG10 other 1.8579048779156e-20 1 1.36055621417759e-20 10.8445260174446 -0.571054648501611 0.311187227488004 -0.985683713379073 12.8246043301019 -0.0768588010988753 0.938764822708097 -60.1640730081421 40.8864134582283 -1.47149304425072 0.141750200993929 PIK3C2G other 1 1 1 -0.0768588010988753 -1.47149304425072 1.07179735818969e-35 199.888842399197 15.6276808462638 12.7906913614112 7.88606526412942e-33 -56.3210141877326 53.7201014601441 -1.0484160054969 0.294925736495541 AEBP2 other 1.53674305217238e-31 1 1.17060752780737e-28 12.7906913614112 -1.0484160054969 1.19893534056377e-10 23.5712395876212 6.3499039677918 3.71206237246737 0.000227851027595012 -164.153341480015 31.8966335866721 -5.14641587595645 3.77532973305655e-07 ETFBKMT other 1.02916609633994e-06 0.00487848108105568 1 3.71206237246737 -5.14641587595645 1.50268717493954e-12 261.055604021216 54.809943932567 4.76292412089299 2.47341664197302e-06 -841.671572281172 194.917270513276 -4.31809644196635 1.88266743952518e-05 ETNK1 other 1.41072271983324e-08 0.223453798397244 0.0232525898511884 4.76292412089299 -4.31809644196635 1.22442283794126e-17 156.850449441896 21.8992288498099 7.16237318298345 2.68872490967511e-12 -276.290926759674 68.9067850705046 -4.00963310763921 6.96127647805234e-05 ZCRB1 essential 1.36890473281832e-13 0.793933582321869 3.23803140872174e-08 7.16237318298345 -4.00963310763921 0.0883277812519013 0.229530242180855 4.74800574913857 0.0483424524543802 0.961461706422808 31.7318668613848 14.7427230836771 2.15237488225752 0.0318229497787908 TMEM117 other 1 1 1 0.0483424524543802 2.15237488225752 0.063858535001808 -20.8119224025129 38.8201361309961 -0.536111525531088 0.592107678778117 258.640788445269 122.170664916733 2.11704494382141 0.0347239290800396 PRICKLE1 other 1 1 1 -0.536111525531088 2.11704494382141 0.0495701010178661 88.7399960415703 65.2730983881241 1.3595186720555 0.174546572756922 -399.64472513967 240.708713968394 -1.66028357906538 0.0974347306112773 C1RL other 1 1 1 1.3595186720555 -1.66028357906538 1.70036256650601e-60 579.219005625634 32.3988184540907 17.8777817606648 1.41986019521554e-56 -140.972521636337 116.831860789461 -1.20662737616051 0.228100128145887 NDUFA9 other 2.61498759102959e-56 1 2.18885647694428e-52 17.8777817606648 -1.20662737616051 2.87403443052974e-10 391.082959527775 68.9759380588326 5.66984618888696 2.32617923366881e-08 -563.214865290219 254.354168406265 -2.21429382824436 0.0272238988486875 CLSTN3 other 2.42338583182267e-06 1 0.000245272338398039 5.66984618888696 -2.21429382824436 0.0495654215925248 2.60368925763568 1.45069194971775 1.79479127746056 0.0732389431378866 -5.33487394409637 4.84368397727938 -1.10140834313738 0.271203383895908 KLRG1 other 1 1 1 1.79479127746056 -1.10140834313738 2.09836568703465e-05 -1.36414054833451 7.50877371724179 -0.18167288024703 0.85590749663684 -130.37058364701 28.3398340423697 -4.60025924824043 5.26096835291749e-06 VAMP1 other 0.123740624564434 0.0645783865320622 1 -0.18167288024703 -4.60025924824043 2.77035925433749e-18 169.60498345063 20.8253034972672 8.14417823360348 2.65237730736686e-15 -201.91943511334 78.599471394289 -2.56896683312824 0.0104671716097788 TAPBPL other 3.14879032847999e-14 1 3.40857007769715e-11 8.14417823360348 -2.56896683312824 0.0348538316536545 18.4529915031618 8.0017208048288 2.30612788839446 0.0214813256345759 -19.2433752370029 30.1783065843429 -0.637655899717936 0.523967975636245 CD27 other 1 1 1 2.30612788839446 -0.637655899717936 0.389109443361709 3.82918242868051 13.3237881966237 0.287394423580738 0.773920176227115 -60.7160433440926 49.1325114546879 -1.23576103778223 0.217082725694854 RBP5 other 1 1 1 0.287394423580738 -1.23576103778223 2.32485866377261e-46 330.134764146702 23.0097801426438 14.3475844662621 8.16841992363503e-40 -295.420333212392 84.2548815535232 -3.5062696399938 0.000492024259285475 PEX5 other 3.482405792465e-42 1 1.23416656626202e-35 14.3475844662621 -3.5062696399938 0.718485924028995 1.93747815759049 2.53145947146426 0.76536013293146 0.444398448738295 -0.903582149280138 9.47211071705611 -0.0953939598333758 0.92403803789639 PIANP other 1 1 1 0.76536013293146 -0.0953939598333758 0.579109086482546 -1.60523957451887 3.20217114644997 -0.50129724524515 0.616368529396544 -9.66792251381448 9.51866701273788 -1.01568029440224 0.310241614097107 SLC38A4 other 1 1 1 -0.50129724524515 -1.01568029440224 0.0175060323591628 322.587240368894 156.015563957478 2.06766063709397 0.0391503492543717 -622.870326228884 458.696459420541 -1.35791396126262 0.17506126727388 AMIGO2 other 1 1 1 2.06766063709397 -1.35791396126262 3.87524352820326e-09 250.49757181138 75.5371623013544 3.31621633881379 0.000974851283969581 -991.77459085044 224.160772370478 -4.42438960377644 1.17405683814611e-05 SCAF11 other 3.07500573962929e-05 0.141109891376781 1 3.31621633881379 -4.42438960377644 0.00159959902400461 393.796086149221 473.57777401226 0.831534138126649 0.406042924549132 4978.20364504965 1379.84286127262 3.60780476152067 0.000337759107133333 COL2A1 other 1 1 1 0.831534138126649 3.60780476152067 0.199957100508202 9.83064303890305 5.47523982349504 1.79547259221749 0.0731479761561384 5.83200316084196 14.5649748291126 0.400412855447226 0.689013804477674 PPFIA2 other 1 1 1 1.79547259221749 0.400412855447226 5.94380010903616e-47 120.803788897995 7.83478552209707 15.4189018394036 1.52602460027175e-44 -88.3155336117398 35.1619301604695 -2.5116804796748 0.0123136597269179 LLPH other 8.91807768359786e-43 1 2.3219990317735e-40 15.4189018394036 -2.5116804796748 0.000281808177167376 -10.4416553593924 29.5460518118747 -0.353402729605852 0.723926536039685 336.726710658292 86.7403738210437 3.88200668068369 0.000116621091013808 LRIG3 other 1 1 1 -0.353402729605852 3.88200668068369 7.32904175168274e-12 64.1485359710729 13.7969331720491 4.64947790723739 4.22095688452664e-06 -170.739775730433 39.2849578523 -4.34618706662141 1.66560270647787e-05 MARCH9 other 6.69068221511117e-08 0.198539842612162 0.0390143044836797 4.64947790723739 -4.34618706662141 0.0340474668355909 90.3610192068572 34.8826023150308 2.59043228457531 0.00985090934594304 27.0688114037113 109.000101888841 0.248337487164152 0.80397003577061 GLIPR1 other 1 1 1 2.59043228457531 0.248337487164152 0.655531907904212 -94.0353530050171 163.870860569156 -0.573838159379976 0.566321674672025 300.226701766347 514.575515200043 0.583445369820275 0.559842653432757 PHLDA1 other 1 1 1 -0.573838159379976 0.583445369820275 1.05420001691004e-22 158.312964907433 16.7567387729471 9.44771933563951 1.10243113052397e-19 -204.187750759879 65.5402065517258 -3.11545784645536 0.00193603203187798 TMEM19 other 1.31511452109527e-18 1 1.51055113504395e-15 9.44771933563951 -3.11545784645536 0.000803033073345578 -1.5421959271089 12.794236700583 -0.120538330124737 0.904102312894252 325.069429519944 86.4026415093996 3.76226263272959 0.00018712629446257 LGR5 other 1 1 1 -0.120538330124737 3.76226263272959 0.333507671950803 -10.5219087688339 15.9576654325225 -0.659363915939092 0.509947418137688 -76.6271268600899 53.2019260266751 -1.44030738326409 0.15036867665004 PTPRQ other 1 1 1 -0.659363915939092 -1.44030738326409 0.135803475696911 2.6199673327214 91.0093659055367 0.0287878869021107 0.97704457787671 -468.396606890088 243.308679829602 -1.92511260682571 0.0547490863813218 DUSP6 other 1 1 1 0.0287878869021107 -1.92511260682571 1.86005891366994e-14 54.8505834600916 14.3016157275807 3.8352717975992 0.000140484418654547 -229.080755150933 38.2346059384669 -5.99145066434332 3.8391623361933e-09 POC1B other 1.88107757939441e-10 5.30649018108639e-05 1 3.8352717975992 -5.99145066434332 2.79121553728882e-08 135.797205489074 34.6378248918911 3.92048882725499 9.99671740620707e-05 -283.774215061751 86.9663242749353 -3.26303563393834 0.00117329076547887 TMTC3 other 0.000210234354268594 1 0.826328660797076 3.92048882725499 -3.26303563393834 0.00429420994413065 -1348.83977679276 813.892830268541 -1.65726951587436 0.0980556573997389 -7013.40508504119 2182.84614767612 -3.21296353960068 0.001393435080366 LUM other 1 1 1 -1.65726951587436 -3.21296353960068 3.97676622151154e-05 -7.10807123706122 2.47262134441976 -2.87471078137491 0.00420614261508349 -27.5816868789998 6.63152662807904 -4.15917607300469 3.72429617231249e-05 KERA other 0.227868704492611 0.433023915954774 1 -2.87471078137491 -4.15917607300469 7.29214904193938e-16 231.257155369005 28.4181008313415 8.13767101262299 2.76418038453279e-15 -51.3498812553415 77.9096478959427 -0.659095280778642 0.510113985168099 SNRPF essential 7.74353306763543e-12 1 3.55058970393237e-11 8.13767101262299 -0.659095280778642 0.00182875261737797 -5.1140149386919 4.45862365457242 -1.14699408043721 0.251889207959893 -43.5620061763932 12.2235402390139 -3.56377983175088 0.000397748524945177 AMDHD1 other 1 1 1 -1.14699408043721 -3.56377983175088 1.63878961984516e-09 93.7240081627793 19.8357155215149 4.72501272067152 2.93578629774505e-06 -161.925152622228 53.4759013190954 -3.02800230810523 0.00257892490684178 NEDD1 essential 1.32741959207458e-05 1 0.0274466660976184 4.72501272067152 -3.02800230810523 0.0001023201250253 -3.39139284724615 12.9516495617456 -0.261850263248558 0.793535819733076 -131.786266540675 31.3457947846524 -4.20427261283546 3.06124381984663e-05 SYCP3 other 0.555393638637326 0.357828790101872 1 -0.261850263248558 -4.20427261283546 0.125160799653863 -2.03709628303429 39.5546191034215 -0.0515008443819923 0.958945264492021 -189.014595672698 96.5110593555352 -1.95847602269487 0.0506828829228505 ASCL1 other 1 1 1 -0.0515008443819923 -1.95847602269487 3.49746857415695e-07 47.9999973940563 11.6999580130519 4.1025786024625 4.71750820683879e-05 136.852540701191 28.8854311729458 4.73777039649549 2.76752017848736e-06 GAS2L3 other 0.00243015676046534 0.0344445561414537 0.401648648730254 4.1025786024625 4.73777039649549 4.93171345462737e-06 50.0907592010092 12.7839416974868 3.91825623006842 0.000100557728552388 -53.829918860399 29.8175918109043 -1.80530739040815 0.0715793327190243 SLC15A4 other 0.0308084139510572 1 0.830807953299826 3.91825623006842 -1.80530739040815 1.58936570943418e-17 158.498557801467 18.3020466102237 8.66015485464497 5.30540127032391e-17 2.06911490191347 43.7997494170548 0.0472403365190895 0.962338921577023 TDG other 1.77071233688062e-13 1 7.03124830356028e-13 8.66015485464497 0.0472403365190895 9.06227696655039e-18 97.2257702010266 16.0059716266947 6.0743435305654 2.34551058135018e-09 -167.549054993019 35.4317060103215 -4.72878881260221 2.88384568583893e-06 RITA1 other 1.01724058949528e-13 0.0358577372577212 2.57044504610166e-05 6.0743435305654 -4.72878881260221 2.50679604444493e-08 60.5464357923829 21.9677746973908 2.75614788600205 0.00604595897278569 -208.445550788601 49.0247311248519 -4.25184485474791 2.4976643668817e-05 SDSL other 0.000189338305236926 0.2938751894073 1 2.75614788600205 -4.25184485474791 2.20721210701089e-12 105.462357359122 25.202786763807 4.18455142867669 3.33406924725632e-05 -268.50510889738 57.5500252839695 -4.66559497710894 3.88330373729847e-06 MMAB other 2.05690096252345e-08 0.0479549178518988 0.287896879500583 4.18455142867669 -4.66559497710894 8.13301243232501e-14 162.199818341266 29.6705630937613 5.4666916104255 7.03221224576903e-08 -259.072180623897 66.3968180463764 -3.90187644900306 0.000107575243513095 GLTP other 8.02809657194802e-10 1 0.000724739794048956 5.4666916104255 -3.90187644900306 4.15997020337138e-11 66.3989536255966 25.0557836518858 2.65004497756345 0.00828493571456827 -305.532777702133 56.083285001916 -5.44784025564293 7.77013893928218e-08 GIT2 other 3.66118977598715e-07 0.00103257376364121 1 2.65004497756345 -5.44784025564293 1.18434956232778e-19 91.7323398190964 18.9080189463787 4.85150454308515 1.60704829787806e-06 -278.078566595753 42.3225164347064 -6.57046390482859 1.18597175452105e-10 TCHP other 1.39350569503486e-15 1.69333047110516e-06 0.015274994071331 4.85150454308515 -6.57046390482859 0.000283036037700036 27.1264130605475 16.4917354396846 1.64484890991353 0.100586177096817 -114.520948980177 37.6696834439439 -3.04013568764375 0.00248002374928453 FAM222A other 1 1 1 1.64484890991353 -3.04013568764375 4.55898211017491e-27 357.502365787171 38.0332092232107 9.39974230649453 1.49843622752779e-19 -135.298247002811 81.5869620557666 -1.65833171861861 0.0978259166576255 NUP58 other 6.05524003873431e-23 1 2.05105950824004e-15 9.39974230649453 -1.65833171861861 9.92273303768024e-21 168.296476662488 25.1413619662283 6.69400794151708 5.40857009546395e-11 -185.612636260612 53.8728653573997 -3.44538266211076 0.000614186329153383 MTMR6 other 1.19231560180766e-16 1 6.27285959671909e-07 6.69400794151708 -3.44538266211076 6.86482606573419e-11 63.2637683576929 20.1887845066711 3.13360957103625 0.00182261497799055 -179.115456029001 43.4758486784025 -4.11988406146929 4.39993286762048e-05 SLC46A3 other 5.97308515979532e-07 0.509468226741775 1 3.13360957103625 -4.11988406146929 4.46138338516861e-14 524.920218413189 66.4047206651995 7.9048629849637 1.57511661817189e-14 317.040587336913 144.442042618428 2.19493287127237 0.0286030419449308 SLC7A1 other 4.44487626664348e-10 1 1.99551524356197e-10 7.9048629849637 2.19493287127237 1.45744579110319e-25 199.671046517548 26.4948401869712 7.53622384994553 2.10147088533191e-13 -224.362266748569 56.4354818627581 -3.9755533104897 7.99382482905445e-05 LNX2 other 1.89774016459547e-21 0.907698809339133 2.5984687497129e-09 7.53622384994553 -3.9755533104897 1.32485500757756e-27 99.0480183897221 22.4902191966475 4.40404860102416 1.2823788837249e-05 -619.342355608234 65.9446835171327 -9.39184665959199 1.66162508326016e-19 SUOX other 1.77013877562438e-23 2.55491472802083e-15 0.114529258105471 4.40404860102416 -9.39184665959199 4.29334918872665e-05 4.57948592067806 3.2945439439577 1.39002119825325 0.165091989311676 -39.1595755310061 10.2639279623557 -3.8152621174495 0.000151671165863308 CCDC65 other 0.245321972643841 1 1 1.39002119825325 -3.8152621174495 2.25702476186967e-20 114.067873465368 14.5591953775738 7.834764937702 2.55456852258591e-14 -170.992735964703 44.7829659323689 -3.81825393661814 0.000150162760073934 TARBP2 other 2.69150202852958e-16 1 3.22361001865116e-10 7.834764937702 -3.81825393661814 0.00174263768570346 25.5398329422841 12.2045022111985 2.09265666885206 0.0368512279508191 -83.2700568133083 36.4886261011805 -2.28208254765214 0.0228769719722977 RDH16 other 1 1 1 2.09265666885206 -2.28208254765214 0.210558507302741 -25.5923408864057 18.7606256675859 -1.36415177936328 0.173085981907975 -81.9130022158321 55.8205152710999 -1.46743543691796 0.142837661953967 ACVRL1 other 1 1 1 -1.36415177936328 -1.46743543691796 4.91699811768615e-07 -0.551412073508325 2.48000968770346 -0.2223427094831 0.824131173770596 40.7397070592814 7.82061468488017 5.20927173896505 2.70129371671425e-07 GPR84 other 0.00336961881005032 0.00350952079675516 1 -0.2223427094831 5.20927173896505 2.07557692767749e-08 5.40556868274945 1.07802997980457 5.01430274112542 7.25438740349581e-07 -6.43281012795798 3.31593735832575 -1.93996732531943 0.0529098042058692 NPFF other 0.000157640067657105 1 0.00704255929131373 5.01430274112542 -1.93996732531943 2.6729212104367e-11 121.65296919936 21.4601145965958 5.66879401560406 2.34992994281618e-08 -172.665805446021 63.32031453 -2.72686272529829 0.00660300587945432 NABP2 other 2.37355403486779e-07 1 0.00024775311387111 5.66879401560406 -2.72686272529829 0.000107878437438514 12.4344326021537 13.7391130834856 0.905038958963069 0.365854420851954 -87.8152444224662 27.2335454989995 -3.22452485761328 0.00133927087116418 N4BP2L1 other 0.583298711230043 1 1 0.905038958963069 -3.22452485761328 3.93106091532739e-11 150.974349753754 61.4541286881821 2.45669986665659 0.0143372953721138 -1040.84111845554 180.883100160023 -5.75421981121915 1.46391939977377e-08 SMARCC2 other 3.46326466640343e-07 0.000199136955951226 1 2.45669986665659 -5.75421981121915 7.58334499246984e-10 101.222191500806 15.3179772644612 6.60806513505204 9.48627773230391e-11 94.7491438096821 30.2954346655473 3.12750567389724 0.00185961838273506 BRCA2 ts 6.24715960479665e-06 1 1.09348323420267e-06 6.60806513505204 3.12750567389724 1.38857009544636e-14 87.1289953452395 12.1543642102707 7.16853583107321 2.48405334323144e-12 -72.5272526897891 35.9406663664947 -2.01797184142923 0.0440845771883064 KANSL2 essential 1.41064835996396e-10 1 2.99378108926254e-08 7.16853583107321 -2.01797184142923 3.54430367242825e-21 113.356409392255 19.7666832958961 5.73472077714678 1.6243505594597e-08 -375.459492511055 57.7581137970845 -6.50054975531434 1.81763658820509e-10 CERS5 other 4.29817706355374e-17 2.5861333376982e-06 0.000172408568381053 5.73472077714678 -6.50054975531434 4.41627306653072e-23 186.239212684972 33.2307079915971 5.6044310801944 3.3521747045893e-08 -742.519761189844 102.21510360308 -7.26428614770262 1.33590786007935e-12 MAP3K12 other 5.54153944388274e-19 1.96004401230843e-08 0.000350872126329362 5.6044310801944 -7.26428614770262 0.0118478708459865 17.168803535983 9.96431124258023 1.72302963225556 0.0854556441697992 80.8434817400464 28.6291310844879 2.82381891023754 0.00492075252891318 ITGB7 other 1 1 1 1.72302963225556 2.82381891023754 5.39301142063702e-12 580.467079053522 298.308354063833 1.94586263222555 0.0521877526620411 -5544.5144949839 881.472556293557 -6.29005912367555 6.54290610251456e-10 GALNT6 other 4.95294168871304e-08 9.20521459562773e-06 1 1.94586263222555 -6.29005912367555 5.53002632495566e-06 58.2609124254266 50.0715951534847 1.1635521546066 0.24511941692542 -625.904554209952 144.441879337857 -4.33326232723633 1.75242892609064e-05 CSAD other 0.0343801736622494 0.208433896469221 1 1.1635521546066 -4.33326232723633 6.17948413128736e-10 47.8770629921795 11.6752141837435 4.10074386976501 4.75516730827491e-05 -143.802788479177 36.1267085536052 -3.98051176640686 7.82061939118048e-05 LMBR1L other 5.12032055118471e-06 0.888265950450279 0.404604347084463 4.10074386976501 -3.98051176640686 2.91464100551072e-20 89.1959325085206 22.697768816894 3.92972248629706 9.60924308593637e-05 -500.267968673739 65.4849663538501 -7.63943232360425 1.00019399103013e-13 C12orf10 other 3.46900572475886e-16 1.48568815427616e-09 0.795453142653813 3.92972248629706 -7.63943232360425 3.37183469383608e-06 428.029417469108 104.692910604494 4.08842790784665 5.00537796349453e-05 -553.281978779684 306.879180019115 -1.80293097350306 0.0719574524491638 ESYT1 other 0.0214381249834098 1 0.424956589100686 4.08842790784665 -1.80293097350306 7.34132859644066e-29 3541.22102905406 657.57877253896 5.38524231155021 1.08276113242159e-07 -17028.8836514343 1911.49951021814 -8.90865185180765 7.9674993553716e-18 TMBIM6 other 9.9408930524403e-25 1.21767292648144e-13 0.00110300876559787 5.38524231155021 -8.90865185180765 6.56969425047652e-10 255.322630738608 51.8692431617109 4.92242830578031 1.13961224181034e-06 -461.523681875115 153.032652985915 -3.01585101525747 0.00268410582154105 ANKRD52 other 5.42985229801884e-06 1 0.0109311606234448 4.92242830578031 -3.01585101525747 2.94907136335825e-09 47.7169146529707 32.2012614118086 1.48183370964071 0.138967835417774 -514.687146950912 92.5196043761683 -5.56300635331605 4.17797946132392e-08 ZNF740 other 2.35424366936889e-05 0.000559891027612019 1 1.48183370964071 -5.56300635331605 1.90911132191349e-09 46.0693595316437 16.1547265802245 2.85175730476544 0.00451616069832871 -104.946582430767 29.8053531795094 -3.52106488383823 0.000466577109677509 WDFY2 other 1.54237103697391e-05 1 1 2.85175730476544 -3.52106488383823 0.717805193713827 -29.4863445016407 43.4711450957557 -0.678296935511819 0.497881161712801 2.11539568475086 75.5917350322625 0.0279844838043207 0.977685120270194 HNRNPA1L2 other 1 1 1 -0.678296935511819 0.0279844838043207 1.08393796699357e-07 -38.7853446868376 27.2236301702605 -1.42469407805897 0.154828708632015 -275.28886125868 50.2697161959714 -5.47623663092694 6.69281660280222e-08 LPAR6 other 0.00078271160596606 0.000890613105334891 1 -1.42469407805897 -5.47623663092694 3.60148143654682e-24 152.362361987902 42.8836584461849 3.5529235962716 0.000414325347822033 -548.14983242066 79.3105065567334 -6.91144031501742 1.35724114159379e-11 ESD other 4.5958504611774e-20 1.96718531062604e-07 1 3.5529235962716 -6.91144031501742 2.91197606489203e-33 185.574067794482 45.2731841581602 4.0989842275327 4.79413213837318e-05 -703.041118772211 83.5990683345698 -8.40967648058693 3.75310599527599e-16 RB1 ts 4.10151828740042e-29 5.67995061325068e-12 0.407740938368639 4.0989842275327 -8.40967648058693 0.452201788650077 8.32416659772926 6.82706319172603 1.21928951936722 0.223264676950104 1.14809178308764 14.9459831224608 0.0768160765123765 0.938798208241286 MORN3 other 1 1 1 1.21928951936722 0.0768160765123765 1.2289681652639e-15 148.287934404997 29.7697267920623 4.98116544504318 8.51115061033184e-07 -329.79666400653 65.3454601640852 -5.04697133019489 6.13730450398021e-07 SETD1B other 1.2955782398212e-11 0.00786741064365223 0.00822602706488572 4.98116544504318 -5.04697133019489 4.01273177387686e-35 212.95352174613 20.7051542144096 10.2850488115625 8.72547680894464e-23 -247.577975475661 45.5810092081415 -5.43160363881192 8.44599514989482e-08 VPS33A other 5.73058224627355e-31 0.00112086801634254 1.23003046575693e-18 10.2850488115625 -5.43160363881192 0.0145265450344068 104.972767668264 37.6997764047607 2.7844400598357 0.00555779419897905 0.060084713549563 81.4678512166956 0.000737526676501436 0.999411822295757 VPS37B other 1 1 1 2.7844400598357 0.000737526676501436 0.000144152319353875 55.3397872344241 17.0094284974011 3.25347716667139 0.0012110385013419 -57.9572574397053 37.0035376254461 -1.56626261051997 0.117870778677021 RHOF other 0.766602034323909 1 1 3.25347716667139 -1.56626261051997 3.36981836805115e-22 415.330592928041 47.2470544590389 8.79061346116538 1.97069524381695e-17 -289.092352253822 104.794154899261 -2.75866867318818 0.00599981072085344 DENR essential 4.16711739393206e-18 1 2.62733089905676e-13 8.79061346116538 -2.75866867318818 3.68629356818704e-07 126.57315265787 24.7520656664807 5.11363998315808 4.5030728858711e-07 186.863323063063 42.1965357852255 4.42840436035249 1.1658926673738e-05 DIAPH3 other 0.00255718184825135 0.140151957545004 0.00443102371969717 5.11363998315808 4.42840436035249 0.00175071252874144 48.129588855324 14.217897190744 3.38514115059552 0.00076517102663114 72.5766748821954 28.5645432341949 2.54079591916292 0.0113496017946593 SLAIN1 other 1 1 1 3.38514115059552 2.54079591916292 1.14368489085302e-36 294.747626121282 27.7711007807638 10.6134657192071 5.77989431563639e-24 -215.628633250142 57.5712307721533 -3.74542337132802 0.000200098430153947 RBM26 other 1.6472493482956e-32 1 8.2294135266031e-20 10.6134657192071 -3.74542337132802 4.75661494020255e-24 629.449343525151 61.9346664803981 10.1631183195984 2.61935333131235e-22 -49.3949950251406 160.240645252027 -0.308255093128537 0.758007991977896 MBNL2 other 6.05897611083e-20 1 3.67547659449749e-18 10.1631183195984 -0.308255093128537 4.88599502601603e-36 105.116498217968 9.70585578458462 10.8302143109235 7.33655724759024e-25 -97.0489381067641 22.9162386617542 -4.23494184797145 2.68896234042785e-05 ABHD13 other 7.02019765337983e-32 0.315684178766229 1.05000807327512e-20 10.8302143109235 -4.23494184797145 4.91979865626026e-09 74.2658998449484 21.9412130276366 3.38476727569277 0.000763766685441809 -198.287106287261 51.6727558431327 -3.83736270790778 0.000138954898380942 RAB20 other 3.87926124046121e-05 1 1 3.38476727569277 -3.83736270790778 1.4553311750224e-32 89.035365579304 11.3029864766414 7.87715403918277 1.84759467436414e-14 -259.985959236712 32.3953939578828 -8.02539890623707 6.32766539354164e-15 GRTP1 other 2.03935557555889e-28 9.49656022262729e-11 2.33794630094039e-10 7.87715403918277 -8.02539890623707 2.18042663021016e-67 716.132376111485 39.6748667073031 18.0500260125553 2.12306337265559e-57 -511.463300672963 113.778770882954 -4.49524367950076 8.49947092849253e-06 CUL4A other 3.36919522900074e-63 0.103090082891686 3.27609909034484e-53 18.0500260125553 -4.49524367950076 8.8801978893286e-14 -15.3132541551787 22.2052127087078 -0.689624294802344 0.490731741814491 -441.260570962678 56.784601158054 -7.7707787316226 4.06252196309814e-14 TTC6 other 8.75054700014441e-10 6.04990770744575e-10 1 -0.689624294802344 -7.7707787316226 1.91238490449873e-15 222.042149240813 26.1848047139419 8.47980925069066 2.26294984898456e-16 131.720362927823 65.1300025336181 2.02242219873757 0.0436354299741582 SSTR1 other 2.00245823350062e-11 1 2.96469059715467e-12 8.47980925069066 2.02242219873757 5.49093749628516e-19 82.1494192350297 8.61626822417907 9.53422260051063 5.13892360259829e-20 86.0593023733452 29.0388233904644 2.96359467517561 0.00317506180479558 CDH24 other 6.34697465195602e-15 1 7.06961720009447e-16 9.53422260051063 2.96359467517561 4.42331998632285e-24 23.9800983620439 2.46173619566897 9.74113245937279 9.09638113922952e-21 -15.6831789730105 8.14108331827244 -1.9264240838575 0.0545749824623726 REM2 other 5.63619432657257e-20 1 1.26012167921747e-16 9.74113245937279 -1.9264240838575 2.11210505139686e-10 6.47231026873481 4.64421045004026 1.3936298404993 0.164011309578421 -73.6478512445471 12.4835448055484 -5.8995944174297 6.488122234868e-09 CBLN3 other 1.79740139873873e-06 8.91662638737909e-05 1 1.3936298404993 -5.8995944174297 6.18339753834575e-07 0.974589940905162 0.913813701833677 1.06650834732455 0.286674050654453 -12.5750938667454 2.61483779492924 -4.80912961068995 1.97251587014271e-06 TSSK4 other 0.00420347364656744 0.0247097063052777 1 1.06650834732455 -4.80912961068995 0.000491827910989616 -27.9589726418742 82.4807957298982 -0.338975544482283 0.734762413313436 -779.812738055413 205.227824402487 -3.79974177636882 0.000161643859627601 NOVA1 other 1 1 1 -0.338975544482283 -3.79974177636882 0.62119435520165 2.23748118383307 6.81568163538822 0.328284286668507 0.742825408233876 -16.9940846939525 21.177732667528 -0.802450619277562 0.422649319704379 FITM1 other 1 1 1 0.328284286668507 -0.802450619277562 7.05093577121432e-18 237.240166486895 34.2830764930395 6.92003725322207 1.27670538103687e-11 -306.822676020875 84.49346391887 -3.63131846879285 0.000308686023796851 TMX1 other 7.93723839765596e-14 1 1.51047013630472e-07 6.92003725322207 -3.63131846879285 3.42017060459016e-09 -161.573269910516 100.256074486288 -1.6116057878629 0.107629884453923 -1484.31845262959 234.079737560637 -6.34108047154267 4.81182566646344e-10 FRMD6 other 2.72142975007239e-05 6.78708010254668e-06 1 -1.6116057878629 -6.34108047154267 0.000827354297646211 -8.21286907032129 11.9508891645796 -0.687218244368195 0.49223969360253 -97.7769840910894 26.1869426632014 -3.73380678105994 0.00020859621996146 PELI2 other 1 1 1 -0.687218244368195 -3.73380678105994 2.35168001481771e-05 -136.11013252838 63.7194096542146 -2.13608590015204 0.0331181298248878 -633.285337945655 136.478642367385 -4.64017905630188 4.36668934557611e-06 RTN1 other 0.137808448868318 0.0538194461842256 1 -2.13608590015204 -4.64017905630188 1.96940492998746e-09 -4.83777025585015 7.38038321790929 -0.6554903875602 0.51242917354404 -97.0261559554187 15.6175610211288 -6.21263178188662 1.03648176584216e-09 C14orf37 other 1.58970365948588e-05 1.45148906488535e-05 1 -0.6554903875602 -6.21263178188662 2.57441611025455e-25 43.0208596160431 6.05540501323652 7.10453875867984 3.82434114399915e-12 -70.8652800467231 13.0070608208516 -5.44821624368198 7.73711452462253e-08 SLC38A6 other 3.33979001983322e-21 0.00102833989146758 4.58806207045578e-08 7.10453875867984 -5.44821624368198 5.63579895385383e-27 110.991612138457 18.1670858023354 6.10948906974333 1.90761558186574e-09 -280.78631708621 39.4349354279581 -7.12024285165031 3.43242167963569e-12 NAA30 other 7.47476015249634e-23 5.01339510527588e-08 2.0985679016105e-05 6.10948906974333 -7.12024285165031 1.69074453828639e-44 210.358454094933 39.3238229518498 5.34938971606364 1.31121459139358e-07 -822.480465597169 77.0860447051465 -10.6696415511154 3.18587930370957e-24 DCAF5 other 2.5197165854082e-40 4.95467949312912e-20 0.00132957159567309 5.34938971606364 -10.6696415511154 0.00926192078759246 97.9583897736052 46.8933184738274 2.08896262754957 0.0371795546452397 -108.613860619989 92.8893403729439 -1.16928228991521 0.242806742607571 RAB15 other 1 1 1 2.08896262754957 -1.16928228991521 3.22867450430288e-23 55.5220742587982 9.31831244096386 5.95838298088395 4.59356836701216e-09 -105.745854069623 18.5928851561557 -5.68743652109378 2.11291315051591e-08 WDR89 other 4.05908958680959e-19 0.000285750374475772 4.97896875300448e-05 5.95838298088395 -5.68743652109378 0.167727601500798 2.02596784420961 1.2660183839332 1.60026731832711 0.110124142248838 -0.652211917189723 2.5494398108545 -0.255825579569623 0.798182940577432 ESR2 other 1 1 1 1.60026731832711 -0.255825579569623 2.06271649304079e-10 92.185188088236 29.7236831519001 3.10140528739767 0.00202627268096728 -258.327692674096 62.1453565891407 -4.15683016161558 3.75005799796561e-05 STON2 other 1.75640309382423e-06 0.435794239943584 1 3.10140528739767 -4.15683016161558 9.85501339435673e-30 25.4925340698624 9.31335386626158 2.73720234793304 0.0063991422719508 -187.253800705676 18.8609983232529 -9.92809593089351 1.844269642968e-21 EFCAB11 other 1.34540642859758e-25 2.8527162837429e-17 1 2.73720234793304 -9.92809593089351 0.373376361286453 -10.1500021973768 7.38629531108649 -1.37416685495124 0.169957853786246 -12.4007255083654 14.8478217931194 -0.835188196703165 0.403979749030818 GPR65 other 1 1 1 -1.37416685495124 -0.835188196703165 9.55450669999541e-27 48.4808748896505 18.416088249149 2.63252837593732 0.00871555593015245 -326.825132698494 36.336345349775 -8.99444150347161 3.91812956498401e-18 PTGR2 other 1.26387014627539e-22 5.99473823442553e-14 1 2.63252837593732 -8.99444150347161 5.17889277434378e-11 12.5086184048277 24.3401073641967 0.513909746479895 0.607523006426622 -297.727582687997 48.3750559860716 -6.15456822982737 1.45835090378426e-09 JDP2 other 4.53049539899594e-07 2.03556619150207e-05 1 0.513909746479895 -6.15456822982737 4.09053341191088e-10 10.5437152343239 3.72976565107243 2.82691091631781 0.00487321603153106 -34.8952058795228 7.73956381270652 -4.50867861858483 7.99694405903635e-06 AK7 other 3.42214025240464e-06 0.0971228855969965 1 2.82691091631781 -4.50867861858483 0.00926487357044883 211.230382962923 140.20246589269 1.50660961358981 0.132489069809641 874.444417532495 286.053756162658 3.05692338832727 0.00234565691468971 FBLN5 other 1 1 1 1.50660961358981 3.05692338832727 1.17592850455227e-05 568.379612736474 193.697641597187 2.93436516856759 0.00348364070487535 1849.76318955418 398.139656711887 4.64601593528966 4.2513329888158e-06 WARS essential 0.0710378409600026 0.0524274384180765 1 2.93436516856759 4.64601593528966 1.81438175914758e-37 55.5796126917028 11.2825751341451 4.92614602879966 1.11503935267289e-06 -243.061226098927 23.4483117004823 -10.3658305639944 4.2844968606108e-23 WDR20 other 2.62613615819021e-33 6.65082447672615e-19 0.0107021477069544 4.92614602879966 -10.3658305639944 3.42415211007398e-21 229.691812501256 33.3325322880538 6.89091997320517 1.58452950326678e-11 -256.726517984068 69.6390496037489 -3.68653104034102 0.000250837489398852 NIPA2 other 4.15315917322876e-17 1 1.86942790795415e-07 6.89091997320517 -3.68653104034102 2.44563280327099e-08 40.9894952860545 22.126798937052 1.85248193390578 0.064503127113441 -163.780027907693 40.4548776341852 -4.04846182921822 5.91131425208731e-05 SLC12A6 other 0.000184865383599254 0.678086857856936 1 1.85248193390578 -4.04846182921822 0.0397789002828692 -5.93303201305131 13.2517217646919 -0.447717822514156 0.654541537392121 47.4216610447703 23.5653781416984 2.01234458278684 0.0446938304111931 DUOXA1 other 1 1 1 -0.447717822514156 2.01234458278684 3.14342957847278e-39 110.115013016834 27.7297604958466 3.97100483552056 8.17146402509835e-05 -496.474351303982 48.0357384254016 -10.3355203350313 6.88913333135722e-23 MFAP1 essential 4.58720678386533e-35 1.06919349302664e-18 0.680764667930944 3.97100483552056 -10.3355203350313 1.35027363621075e-09 41.6140096134317 67.1723177540673 0.619511295795833 0.53584039257201 -709.307326183145 124.288563439823 -5.70693961336654 1.89685657517531e-08 TCF12 other 1.09817754833021e-05 0.00025698612880475 1 0.619511295795833 -5.70693961336654 1.02719838071097e-06 306.177430721036 221.220296785149 1.38403860391887 0.166929159211566 -1542.40999607593 395.546291434729 -3.89944244068447 0.000108800280432296 SORD other 0.00684935880258077 1 1 1.38403860391887 -3.89944244068447 7.60087703858012e-11 1852.5361914643 579.232385311156 3.19826072996444 0.00146798096737619 -3924.6612082735 1007.985555873 -3.89356889630668 0.000111830380570179 SERF2 other 6.59756126948754e-07 1 1 3.19826072996444 -3.89356889630668 1.18504583659951e-28 86.7575714040997 21.3518186123205 4.06324037213574 5.5753035427654e-05 -287.035436880233 36.7178764262643 -7.81732128372534 2.94477620792459e-14 ZSCAN29 other 1.60087842066228e-24 4.39213371411952e-10 0.471893691859663 4.06324037213574 -7.81732128372534 0.17061321887984 -2.75537035016091 4.22356284003018 -0.652380574060836 0.514445080525262 9.50204208802671 7.55271495934808 1.25809621297384 0.208923762922622 DUOXA2 other 1 1 1 -0.652380574060836 1.25809621297384 0.596711976472468 3.42143675375471 5.02736308160524 0.680562891165251 0.496452189696984 8.89371667909617 9.01956527753195 0.986047154761519 0.324570316151634 DUOX2 other 1 1 1 0.680562891165251 0.986047154761519 6.00346027189733e-07 43.4989039863068 8.01926781922659 5.42429869744667 8.7996204739997e-08 36.1642652810185 17.6262594797776 2.05172659136837 0.0406788540571908 LYSMD2 other 0.00408475436899894 1 0.00090196109858497 5.42429869744667 2.05172659136837 4.14925436740093e-05 263.214482703314 101.208658929107 2.60071110010148 0.00955989441915342 -462.75599046739 198.946496005601 -2.32603237432421 0.020388886123067 SLC27A2 other 0.237295857271659 1 1 2.60071110010148 -2.32603237432421 0.508077150916338 11.6564842492876 18.744453027648 0.621863131033714 0.534295790125392 -23.0708937255805 36.721746793148 -0.62826242595533 0.530099144615554 FGF7 other 1 1 1 0.621863131033714 -0.62826242595533 0.434997310111419 -96.8512787591797 137.384210578554 -0.704966592240248 0.481137814393004 -345.438084058433 270.784899204595 -1.2756918316831 0.202618079240038 HDC other 1 1 1 -0.704966592240248 -1.2756918316831 0.585626978749083 38.2316666776068 38.5627838388214 0.99141355658869 0.321924445424252 5.31228929154298 70.3901171485619 0.0754692491892168 0.939869108066967 GCNT3 other 1 1 1 0.99141355658869 0.0754692491892168 3.21807712013321e-06 194.789386967393 38.7764144522146 5.0233986230841 6.89529199047317e-07 73.0707265644536 70.780065238568 1.03236308582317 0.302360793950347 BNIP2 other 0.0204959331781284 1 0.00670222381473992 5.0233986230841 1.03236308582317 2.9538308110082e-17 171.55781984714 20.9320581332181 8.1959365273731 1.79218078655235e-15 -24.5571578332919 38.208082443323 -0.642721546408915 0.520675585892159 GTF2A2 essential 3.26900455854278e-13 1 2.31137556041656e-11 8.1959365273731 -0.642721546408915 4.64479736698092e-32 980.295489466729 153.67678485149 6.3789432503684 3.82559989295828e-10 -1832.35520056438 271.345119306687 -6.7528585192401 3.74278916020946e-11 SRP14 essential 6.47856336746498e-28 5.38849355395355e-07 4.32866627888229e-06 6.3789432503684 -6.7528585192401 5.87046604271719e-25 146.11145194339 30.0534830839099 4.86171441544542 1.52589756838845e-06 -343.534749636916 53.2741974806364 -6.44842655324429 2.50055892412647e-10 BAHD1 other 7.58111984756497e-21 3.54954339279752e-06 0.014514337670511 4.86171441544542 -6.44842655324429 0.0104445223215887 28.655389321792 19.9505853230098 1.43631822614961 0.151487673853252 -58.4077371221835 35.2935108514305 -1.65491433731411 0.0985197093116211 DISP2 other 1 1 1 1.43631822614961 -1.65491433731411 2.37650462559963e-29 31.2230563740077 15.1806417787457 2.05676787774038 0.0402030668786747 -241.63219746351 25.8748307920089 -9.33850348262507 2.77583706481131e-19 CDAN1 essential 3.23228394127805e-25 4.26285298043073e-15 1 2.05676787774038 -9.33850348262507 3.65435848531143e-15 -54.4866518647533 111.209864805473 -0.489944412395974 0.624371852604483 -2016.61415538006 246.179579800581 -8.19163862824703 1.86889986366763e-15 TLE3 other 3.7935895436018e-11 2.81624520456075e-11 1 -0.489944412395974 -8.19163862824703 2.10149811918599e-26 616.69110652627 71.592038622815 8.61396208837309 7.69402581121883e-17 -744.18597851643 155.251820974646 -4.79341223725782 2.11975635861024e-06 ANP32A other 2.76746287315603e-22 0.0265139125334968 1.01668857069446e-12 8.61396208837309 -4.79341223725782 1.77952074177131e-11 283.60647496017 49.3627705002375 5.74535165036585 1.53522575259486e-08 -290.211572795844 107.159048305643 -2.70823208478012 0.00697918101065169 COMMD4 other 1.59249311181115e-07 1 0.000163163792985781 5.74535165036585 -2.70823208478012 3.31174734884088e-13 172.249818772168 39.4347437546839 4.36797104207653 1.50343727769848e-05 -427.720271991489 84.7449893780979 -5.04714526640831 6.13541479915543e-07 UBE2Q2 other 3.18954387166865e-09 0.00786560177251726 0.133475161514071 4.36797104207653 -5.04714526640831 0.0150918803503205 -3.15812465339241 5.82558158775909 -0.542113196050394 0.587963331691171 33.3211985793789 12.7575647004738 2.61187768682383 0.00925427189549509 PSTPIP1 other 1 1 1 -0.542113196050394 2.61187768682383 2.47559362046516e-24 739.625778255241 68.5260794309862 10.7933473561716 9.84159862564092e-25 144.123974253004 149.591009537416 0.963453450168441 0.335749661732063 ETFA other 3.16801715610927e-20 1 1.40705335550788e-20 10.7933473561716 0.963453450168441 9.24458262767847e-08 14.7820376280193 23.3592827210626 0.632812137450204 0.52712174666054 298.547340148653 52.3448739808117 5.70346850501719 1.92686255478081e-08 BCL2A1 other 0.000669492673896475 0.000260954995793965 1 0.632812137450204 5.70346850501719 6.81397624116085e-27 220.243237704564 21.143711257151 10.4164890934214 2.77296172516354e-23 -102.205847696161 47.1203073851699 -2.16904034306721 0.0305136565465077 HMG20A other 9.02919991716224e-23 1 3.9254046181415e-19 10.4164890934214 -2.16904034306721 2.69478488622592e-23 127.418658116038 13.7252307677671 9.28353484702589 3.92145779094723e-19 -79.8620357090748 30.1121404700965 -2.65215406352077 0.00823228321400383 SCAPER other 3.39138677931532e-19 1 5.33945692815375e-15 9.28353484702589 -2.65215406352077 1.07163557572881e-09 936.624989429753 165.072844077172 5.67401012968481 2.27340688312063e-08 -600.587336465503 361.496523030556 -1.66139173741026 0.0972130632438623 TSPAN3 other 8.75847756043156e-06 1 0.000239821692100395 5.67401012968481 -1.66139173741026 2.14597554182457e-58 472.930907272542 29.0581029027203 16.2753538610488 8.7606554526315e-49 -300.858081950283 70.196400160836 -4.28594744546656 2.15369874676308e-05 WDR61 essential 3.29020970072543e-54 0.254653339817266 1.34125634979788e-44 16.2753538610488 -4.28594744546656 1.18319731405711e-22 353.749211458315 34.9108375843975 10.1329339521895 3.55072865690143e-22 -532.045111165322 315.350744969329 -1.68715349385671 0.0921622419833279 NCOA2 other 1.47438217304656e-18 1 4.97634621264735e-18 10.1329339521895 -1.68715349385671 5.34559734355588e-15 156.556978292803 32.4361093189803 4.82662629951096 1.8144395841333e-06 -376.404754840393 70.4271078020602 -5.34460048960553 1.34358865160848e-07 NEIL1 other 5.51719101828402e-11 0.00176856574211224 0.0171845573013265 4.82662629951096 -5.34460048960553 3.98003535989766e-23 921.24751169335 106.079988011678 8.68446093330943 4.4894476339049e-17 -950.821162227137 256.260132068957 -3.71037490127915 0.000228311589111145 DNAJA4 other 4.99773040142349e-19 1 5.95615017590163e-13 8.68446093330943 -3.71037490127915 0.159265358904936 526.030233737256 298.472393162199 1.76240833587378 0.0785649689677117 -150.599012238315 658.92743190277 -0.228551741734949 0.819303700310325 TPM1 other 1 1 1 1.76240833587378 -0.228551741734949 3.24310510503961e-25 2596.01799109986 302.164744036198 8.59139936851424 9.29640575590594e-17 -4313.09869709519 873.711164250955 -4.93652693655674 1.06193463339007e-06 IGF1R other 4.20176697408932e-21 0.0134706408245531 1.22638184731911e-12 8.59139936851424 -4.93652693655674 1.6883904433977e-05 66.2580619441562 19.5830364624955 3.38344168796553 0.000767874599615508 -136.708481601463 55.7742726504698 -2.45110290291364 0.0145584264322591 ARRDC4 other 0.100594302617635 1 1 3.38344168796553 -2.45110290291364 1.09113230983833e-07 18.9797012139934 6.15439342660556 3.08392718800585 0.00214754991959313 76.9271255687317 13.9838078477368 5.50115722458114 5.83782963015501e-08 PIF1 other 0.00078741812534944 0.000778532959477473 1 3.08392718800585 5.50115722458114 9.5701530008091e-35 258.303602135229 24.7547079571074 10.434524316861 2.40614207965094e-23 -288.30600711972 54.8275045294527 -5.2584192841541 2.09712318295384e-07 USP3 other 1.36240698119518e-30 0.00273443891825351 3.40902209844945e-19 10.434524316861 -5.2584192841541 0.000127739328468149 6.19732221527222 2.66428264204606 2.32607536357814 0.02038312616868 21.0418765209221 5.13639094807528 4.09662674310392 4.83410955817071e-05 CYP11A1 other 0.686087933202427 0.558387995064299 1 2.32607536357814 4.09662674310392 1.39888084962985e-31 154.328871345881 20.6525878234772 7.47261663598616 3.21138917137738e-13 -360.308175600796 45.486742037929 -7.92116910242448 1.36261064603345e-14 BBS4 other 1.94220617162608e-27 2.03846552646604e-10 3.95354120888269e-09 7.47261663598616 -7.92116910242448 7.50161476162426e-06 265.217686442233 65.9775148680602 4.019819281957 6.64933202720208e-05 501.33735409458 130.349971225311 3.84608718653275 0.000134282812613625 PML other 0.0461049243249427 1 0.558610383605247 4.019819281957 3.84608718653275 6.14694249363638e-06 31.5750919912765 6.55545367052548 4.81661431507691 1.89574141436599e-06 1.30632715171957 21.8877471200463 0.0596830338250365 0.952430002771841 ADAMTS17 other 0.038018839323141 1 0.0179356095213167 4.81661431507691 0.0596830338250365 9.51176463252954e-47 83.5129479734074 6.02341755443696 13.8647117219842 1.249644231953e-37 -91.9046372386512 20.0499155295075 -4.58379174233403 5.6739116415997e-06 LINS1 other 1.42619398900148e-42 0.0695110915212379 1.87859017389494e-33 13.8647117219842 -4.58379174233403 7.49201929487837e-13 159.697908471077 35.2678501828898 4.52814412114506 7.34404528285842e-06 -317.815152653702 67.8756564031137 -4.68231424188661 3.6017393717005e-06 ULK3 other 7.1084279069806e-09 0.0445319055917049 0.0668381561192945 4.52814412114506 -4.68231424188661 5.42038952438079e-14 866.957298637538 126.044981273921 6.8781580184733 1.69523251270896e-11 -960.995802614044 406.108332563377 -2.36635332387343 0.0183189206402324 PCSK6 other 5.3862410703772e-10 1 1.9978315162275e-07 6.8781580184733 -2.36635332387343 8.0815526629148e-14 29.7434583926751 4.2175716693436 7.05227100439627 5.44318513965166e-12 -16.0813205536493 9.29312509536007 -1.73045346841167 0.0841237767324098 CELF6 other 7.97891694409578e-10 1 6.50449798035038e-08 7.05227100439627 -1.73045346841167 5.50822819785668e-31 463.524927086539 62.9354290107102 7.36508727075901 6.75285072771997e-13 -942.456927738337 121.124013314142 -7.78092553203319 3.7477656535898e-14 SCAMP2 other 7.60741396405985e-27 5.58379604728345e-10 8.23442617738173e-09 7.36508727075901 -7.78092553203319 5.63613259141095e-17 345.383244332916 69.6180410392647 4.96111696303144 9.41084087374668e-07 1415.15787006346 165.761371196546 8.53732000313561 1.40511201005258e-16 HAPLN3 other 6.18565551907352e-13 2.13239798645579e-12 0.00907016843411705 4.96111696303144 8.53732000313561 0.831294902390584 61.3953627729788 103.60317378682 0.59260117744375 0.553695698710385 74.3599596501582 255.484092260256 0.291055145517277 0.77112069439959 RHCG other 1 1 1 0.59260117744375 0.291055145517277 3.61491701538936e-28 388.703671020073 32.6020809376749 11.922664438603 3.00234351762829e-29 217.998337889123 80.5034277231692 2.70793858168082 0.00698527153836054 POLG other 4.86061741889253e-24 1 4.39693208156663e-25 11.922664438603 2.70793858168082 2.51880742894665e-27 726.123168664839 62.8550103527768 11.5523514289384 9.92127039768109e-28 781.962605449693 154.860538597638 5.04946329472228 6.07506328433723e-07 FANCI other 3.35454773387115e-23 0.00779005364950562 1.44275114123078e-23 11.5523514289384 5.04946329472228 1.01561564520942e-08 2945.97348988325 666.109220521719 4.42265832557589 1.17985234477159e-05 -4863.71495489789 1644.80529916233 -2.95701561599717 0.00324247744896774 ABHD2 other 7.84867770617837e-05 1 0.105702971568087 4.42265832557589 -2.95701561599717 8.7441419941288e-55 17.8299342117795 1.10982401936003 16.0655508447735 7.87792641431536e-48 -36.9670925250819 6.92500291688561 -5.33820605836036 1.37971519692149e-07 WDR93 other 1.33278212274511e-50 0.00181570519914868 1.20421983169225e-43 16.0655508447735 -5.33820605836036 4.09897003349182e-21 51.7213549670947 6.08296219750224 8.50265927812806 1.80097607924965e-16 249.342069799607 37.7944922969961 6.59731232371719 9.9573111766234e-11 TICRR other 4.96385271055859e-17 1.42369635203361e-06 2.36270051836762e-12 8.50265927812806 6.59731232371719 0.377288573958731 41.2417775400343 33.9604156136963 1.21440732672899 0.225121055593029 81.970322412869 81.4067600646262 1.00692279545084 0.314421188497368 NTRK3 other 1 1 1 1.21440732672899 1.00692279545084 1.95511343219397e-26 44.0432922871165 5.20897630717011 8.45526830799582 2.59023492294312e-16 -62.6187678477136 12.4044754272882 -5.04807867247338 6.10343810541498e-07 DET1 other 2.57566643557234e-22 0.00782521799495254 3.38932239667107e-12 8.45526830799582 -5.04807867247338 8.10884809711506e-06 2157.70416902773 538.150920130142 4.00947780318936 6.94181923289496e-05 4869.99481719233 1281.22985039863 3.80103134162628 0.000160505836144033 MFGE8 other 0.0496748034429268 1 0.581793869908927 4.00947780318936 3.80103134162628 4.32133320053081e-14 49.1865318632248 6.30993448210383 7.79509391147041 3.28454434685359e-14 -40.4342054002121 39.3936512657564 -1.02641425968453 0.305151696965997 ZNF710 other 4.30880133424927e-10 1 4.13754051373147e-10 7.79509391147041 -1.02641425968453 1.59508125621095e-35 631.729773225491 52.5373180815405 12.0244008695879 1.23479252900362e-29 -430.095928475892 133.11824418473 -3.23093150086205 0.00131003554860012 UNC45A essential 2.28447537514532e-31 1 1.81218151556571e-25 12.0244008695879 -3.23093150086205 0.0240860564419391 18.3534475538143 6.76445427440359 2.71321925011201 0.00687842988115541 17.7080211813538 17.4015309771727 1.01761282984716 0.30932280704323 ST8SIA2 other 1 1 1 2.71321925011201 1.01761282984716 1.83291745152396e-05 41.2574483566545 16.053894965588 2.56993386621073 0.0104398519795259 197.269385868537 44.4164660832104 4.44135707462565 1.08552005582471e-05 MCTP2 other 0.108856967446008 0.130772601125203 1 2.56993386621073 4.44135707462565 0.000308305557471183 552.731200660963 146.522095304044 3.77234027068753 0.000179704966709138 -176.451544939497 370.056417538646 -0.476823361456959 0.633681882180134 FURIN other 1 1 1 3.77234027068753 -0.476823361456959 0.00034861604443887 344.908204090102 116.256575765949 2.96678447492279 0.00314209185825261 -1636.00092650503 712.337758370758 -2.2966646191083 0.022018389825307 IQGAP1 other 1 1 1 2.96678447492279 -2.2966646191083 1.29278848222127e-16 181.257747933883 26.0810080158545 6.94979840593957 1.05416226852484e-11 -304.246751107916 80.3746935128573 -3.78535503913612 0.000170622383063984 CRTC3 other 1.40358045514763e-12 1 1.25034186669732e-07 6.94979840593957 -3.78535503913612 2.14772642614507e-16 146.458690557628 21.2697357967128 6.88577855209013 1.61390767000692e-11 -143.37717408015 45.171206582305 -3.17408333600537 0.00158938881262931 EFL1 other 2.31825590438098e-12 1 1.90360409677317e-07 6.88577855209013 -3.17408333600537 7.88021638626379e-22 356.293774928474 41.3385217876495 8.61892877444211 7.59017164231944e-17 -352.92112024527 108.389842715166 -3.25603498819258 0.00120105973625533 SEC11A other 9.67926978724781e-18 1 1.00304118253251e-12 8.61892877444211 -3.25603498819258 2.89268793765521e-30 526.842680115232 52.0259426277375 10.1265379060013 3.43272254359822e-22 -1132.16474540743 264.518320964073 -4.28009954577474 2.20916602602953e-05 GLYR1 other 3.9658751625253e-26 0.261035057635649 4.81233373387034e-18 10.1265379060013 -4.28009954577474 1.32774685854933e-21 235.330176885239 25.2961058604137 9.30301992661689 3.38464239045549e-19 -165.555803824707 124.930439011209 -1.3251838794055 0.185670594024015 PMM2 other 1.62224111177557e-17 1 4.61326757819084e-15 9.30301992661689 -1.3251838794055 5.6058101124535e-33 394.551906305506 34.3564083344285 11.4840847874697 2.68014496133044e-27 -688.055347262739 202.057795471821 -3.40524029600578 0.000713386701423452 SLC5A2 other 7.88232959912087e-29 1 3.8891583533866e-23 11.4840847874697 -3.40524029600578 0.0150845429865546 20.8609524297398 13.8133511170703 1.51020214088095 0.131609936560496 225.934549364134 81.3583698559989 2.77702896166712 0.00568731398396808 ITGAX other 1 1 1 1.51020214088095 2.77702896166712 0.158032057117518 -1.94806884336374 18.7772623727535 -0.103746158768621 0.917411658677534 -208.992945216514 110.608257366131 -1.88948773078229 0.0593945605091625 TGFB1I1 other 1 1 1 -0.103746158768621 -1.88948773078229 1.92916129993619e-38 603.635266227734 48.4212689799107 12.4663247978523 2.61867624918827e-31 -1126.69813410604 284.776416929018 -3.95643061408021 8.69013871464377e-05 C16orf58 other 2.80596511075719e-34 0.98407130804626 3.86778482005107e-27 12.4663247978523 -3.95643061408021 2.24528249325031e-20 100.356319830737 11.5007812779059 8.72604368396529 3.77580258681407e-17 -171.193761051331 67.7458380378194 -2.52700041817715 0.011805937606414 ARMC5 other 2.67817295794897e-16 1 5.01351067477172e-13 8.72604368396529 -2.52700041817715 4.27871406915155e-43 407.85942184245 29.6512331479504 13.7552262938731 3.84618083160744e-37 -429.73563921682 154.737577026913 -2.77718992033898 0.00567292786222435 PARN other 6.34790019299325e-39 1 5.77619437290806e-33 13.7552262938731 -2.77718992033898 4.05812909693858e-06 -9.89225680933874 90.4399913243215 -0.1093792321791 0.912942872479138 -810.573597963492 203.51730770994 -3.9828239036984 7.75626114160743e-05 FTO other 0.0255723074812429 0.881188828298021 1 -0.1093792321791 -3.9828239036984 1.75270011544932e-28 672.723842925659 62.9864186327769 10.6804587009109 2.65015167669941e-24 -869.991249640448 340.709092118257 -2.55347236033983 0.010937109378875 UQCRC2 essential 2.36316556566032e-24 1 3.77805623030267e-20 10.6804587009109 -2.55347236033983 0.2819002877132 -2.13835738032939 9.21454062050656 -0.23206337335695 0.816576385114547 72.733811809537 49.6771203879804 1.4641309971569 0.143737896571526 IGSF6 other 1 1 1 -0.23206337335695 1.4641309971569 1.65953640409411e-15 142.313498008741 17.7783604851915 8.0048718849683 7.32358111919746e-15 -96.0079087561232 99.5552615585895 -0.964368002786286 0.335291527698218 ARHGAP17 other 1.74135154881595e-11 1 9.34342479187212e-11 8.0048718849683 -0.964368002786286 0.0470822537756229 0.383123173530985 1.36848514563552 0.279961514199019 0.77962738701949 -6.88213381508296 3.62706386087887 -1.89743938321928 0.0583685565877053 MYLK3 other 1 1 1 0.279961514199019 -1.89743938321928 0.00207371709775289 -7.69771623378097 11.3679719287407 -0.677140679272746 0.498633028730148 -98.9555029872529 30.3364273958706 -3.26193660499136 0.00118289314093258 ABCC12 other 1 1 1 -0.677140679272746 -3.26193660499136 0.922392412995489 1.4722170099312 9.49558955775248 0.155042191006375 0.876849276353225 -5.42578917831222 24.5339414495338 -0.221154403155035 0.825060552103367 NKD1 other 1 1 1 0.155042191006375 -0.221154403155035 7.2432690047066e-71 284.858059286907 25.5938493627638 11.1299420126049 4.54708444533399e-26 -459.143625910494 57.4597976445591 -7.99069340185834 8.04340044976189e-15 DHX38 other 1.12147533999872e-66 1.2061078974418e-10 6.55234868572628e-22 11.1299420126049 -7.99069340185834 3.79420700663599e-45 70.0667465438089 7.53516269717677 9.29863751582446 3.41475977426493e-19 -83.3144488069277 16.9169130310085 -4.92492032406938 1.12061189113753e-06 TXNL4B other 5.66854526791417e-41 0.0142003938844948 4.65397609634567e-15 9.29863751582446 -4.92492032406938 4.9949492710619e-28 153.937914809907 24.9471601655906 6.17055864427538 1.33797792287195e-09 -256.455470870032 54.5494289368726 -4.70134107484086 3.28674713809858e-06 MARVELD3 other 6.70521990147349e-24 0.0407458042710081 1.48207814516525e-05 6.17055864427538 -4.70134107484086 2.12762383752894e-09 28.4897713066507 4.6459673522887 6.13215056119928 1.68171888195613e-09 19.8106531001727 10.1648205959568 1.94894271995835 0.051822597728204 CHST4 other 1.71465205066457e-05 1 1.85392689546844e-05 6.13215056119928 1.94894271995835 1.8575455453671e-10 183.831099917896 42.7596905335033 4.29916815637054 2.03253447878109e-05 -167.113553955077 95.3053256817489 -1.75345451851365 0.0800882278178434 ZFHX3 other 1.58374333197999e-06 1 0.178517503271343 4.29916815637054 -1.75345451851365 2.12612695382594e-15 99.0247817416053 26.7885216158195 3.69653776202147 0.000240705624799412 -213.659107206247 56.7243851309526 -3.76661830204063 0.000183519174925688 CPNE2 other 2.22286573022502e-11 1 1 3.69653776202147 -3.76661830204063 1.50234554930456e-08 237.509812906003 49.056981980553 4.84150886004679 1.6824247837241e-06 7.0297587329053 104.350386607752 0.0673668681202864 0.946314442112607 NLRC5 other 0.000114944457977292 1 0.0159678936223255 4.84150886004679 0.0673668681202864 3.33890665872983e-59 116.287445352543 12.6675187266355 9.17997027373877 8.90711344142444e-19 -207.212191889819 27.5759535913681 -7.5142348642 2.36256744898695e-13 KATNB1 essential 5.12422004915267e-55 3.49400100030679e-09 1.20878436513571e-14 9.17997027373877 -7.5142348642 0.00837187864864468 14.2613530642773 22.2374203487814 0.641322277521227 0.52158341618633 -99.3316593002395 48.5019108034288 -2.04799476257371 0.0410400593539029 KIFC3 other 1 1 1 0.641322277521227 -2.04799476257371 0.264287174078139 10.3984662972922 9.84227005627539 1.05651097133453 0.291202062955569 36.3102524584701 22.2983892197371 1.62838006371916 0.104021154398596 ADAMTS18 other 1 1 1 1.05651097133453 1.62838006371916 6.25764103917745e-14 19.4094910386978 3.81364152109623 5.08949017135689 4.94471534247412e-07 -17.8072987137322 8.56375967223228 -2.07937861351619 0.038047809873408 NUDT7 other 6.20507685444836e-10 1 0.00485175469403561 5.08949017135689 -2.07937861351619 1.32397453194643e-29 53.5419280272311 7.59397633607886 7.05057872946669 5.39799621432005e-12 -61.9590843139525 16.1416886871059 -3.83845120017993 0.000138273917609605 GCSH other 1.80470968449617e-25 1 6.45114527573389e-08 7.05057872946669 -3.83845120017993 0.40465782627901 -75.9057418806554 57.1101327341216 -1.32911163477832 0.184375554204733 -119.25844110067 124.306000158664 -0.959394083539398 0.337792008160035 CMTM3 other 1 1 1 -1.32911163477832 -0.959394083539398 0.00999580755531812 -547.872361036056 183.589292488336 -2.98422829354748 0.00297161180473171 -514.528820100867 398.013445863112 -1.29274230669541 0.196653037078636 CDH11 other 1 1 1 -2.98422829354748 -1.29274230669541 4.22201723898443e-24 184.215384615385 34.3596431243859 5.36138818288956 1.24978702448085e-07 -342.462237762239 75.1811317900939 -4.55516204143342 6.54466962930201e-06 NOL3 other 5.38264977798124e-20 0.079897326834519 0.00126878378725295 5.36138818288956 -4.55516204143342 4.90530576707219e-43 188.937790663481 42.7284839543809 4.42182294286877 1.18304286600684e-05 -789.695863815286 90.9954616799264 -8.67840933202818 4.70416045049844e-17 MAP1LC3B other 7.27554951372148e-39 7.16020262170368e-13 0.105941488650912 4.42182294286877 -8.67840933202818 8.64101283149812e-21 252.205191433262 146.988810399889 1.7158121815336 0.0867626637115389 -2182.12333615938 319.079010959339 -6.83881816481327 2.14202712447007e-11 MBTPS1 essential 1.04020512465574e-16 3.09565760028415e-07 1 1.7158121815336 -6.83881816481327 0.227172827956254 -41.4303645661972 27.5758050323647 -1.50241722834825 0.133566449697773 -92.8442890238032 58.8766007686083 -1.57693018638579 0.11538971126707 CDH13 other 1 1 1 -1.50241722834825 -1.57693018638579 1.79662210256607e-32 186.631106226151 29.3680573334655 6.3549013169993 4.4318173073481e-10 -302.969271750985 62.5295244779589 -4.84521950679121 1.65415463059329e-06 ZCCHC14 other 2.51509128138225e-28 0.0207894153972965 5.00396492172673e-06 6.3549013169993 -4.84521950679121 1.3387405405969e-31 256.467637453824 29.96349349502 8.55933696437798 1.15093949300038e-16 -141.347083988339 63.3910045679874 -2.22976564185448 0.0261681039387688 TLDC1 other 1.85897511467286e-27 1 1.5153269364843e-12 8.55933696437798 -2.22976564185448 4.96116392426488e-07 14.0031988834399 19.5709157454472 0.715510662126141 0.474598853666933 -162.316924272571 41.7222169905801 -3.89041944509369 0.000112397131146876 OSGIN1 other 0.00339790117172901 1 1 0.715510662126141 -3.89041944509369 0.906429734701044 7.59424586568415 23.4391282319777 0.323998648350898 0.746062904526598 21.6802155196737 49.481933886392 0.438144062223809 0.661454825881295 IRF8 other 1 1 1 0.323998648350898 0.438144062223809 1.28259463008939e-16 382.992559049364 51.9031867557643 7.37897965401574 6.14330615220134e-13 -472.702544028121 226.951195584742 -2.08283786657391 0.0377412493542187 RHOT2 other 1.39264124935106e-12 1 7.50159114245306e-09 7.37897965401574 -2.08283786657391 0.375766241285516 30.6097076010029 22.9159373533848 1.33573884100716 0.182195261784007 4.74278725658008 104.806975586864 0.045252591538139 0.963922642553347 RPL3L other 1 1 1 1.33573884100716 0.045252591538139 4.27187683572388e-32 74.5052619966148 8.00254731172737 9.31019325401934 3.12552749184847e-19 -196.705666230984 36.7775406494782 -5.34852692043111 1.30792827930582e-07 ZSCAN32 other 5.95969537351839e-28 0.00172201837253405 4.26165673513538e-15 9.31019325401934 -5.34852692043111 4.76090801453744e-05 1160.33809126687 363.918738859431 3.18845381500146 0.00151293363217049 -3236.82698637553 1664.39721801776 -1.94474429020645 0.0523226269482141 RPS2 essential 0.270038702584564 1 1 3.18845381500146 -1.94474429020645 6.22865526838871e-22 385.610981955686 44.636755822043 8.63886666614018 6.37972692092356e-17 -512.3268108257 204.148026134601 -2.50958493464887 0.0123777692983966 NDUFB10 essential 7.66498317327914e-18 1 8.44165466176605e-13 8.63886666614018 -2.50958493464887 8.30039195376086e-14 187.533794998302 33.4450118605756 5.60722764219928 3.27385766445557e-08 -530.849690723671 154.437052055193 -3.4373207961387 0.000632442995976047 PDPK1 other 8.19082677997122e-10 1 0.000342805636045142 5.60722764219928 -3.4373207961387 0.000405762196673333 29.7029200085217 8.5967286406698 3.455142211655 0.000592919993982692 -31.3139952162681 39.9541537848802 -0.783748177595446 0.433528986635712 TIGD7 other 1 1 1 3.455142211655 -0.783748177595446 1.96102683206121e-34 153.933071387907 22.426243795124 6.86397030167734 1.89895304397136e-11 -227.294959244412 48.5739766608295 -4.67935661993483 3.66820238619459e-06 DEF8 other 2.78681523104219e-30 0.0453389814933651 2.23335867501471e-07 6.86397030167734 -4.67935661993483 2.1750926731621e-41 239.241415858691 58.211796874973 4.10984420172654 4.59068830041496e-05 -1086.59529589909 126.440556086043 -8.59372443094655 9.59834808899788e-17 TCF25 other 3.20369399830046e-37 1.457797107757e-12 0.391264363844367 4.10984420172654 -8.59372443094655 1.32803935902193e-29 164.833082179269 23.5305719883721 7.00506057654372 7.49245306688562e-12 -174.910248180729 50.575768279269 -3.45838044841771 0.000586973993732089 GALNS other 1.80998484241099e-25 1 8.91901613082064e-08 7.00506057654372 -3.45838044841771 1.03341099735838e-35 89.7826642999024 16.5126693676788 5.43719869275885 8.31857998783404e-08 -229.008191177391 35.7579248645574 -6.40440383620751 3.36573011750908e-10 GAS8 other 1.48191137021192e-31 4.7635178353106e-06 0.000853819049951285 5.43719869275885 -6.40440383620751 1.20079366835433e-48 84.2761235810055 9.65018858064644 8.73310639234783 3.21775816469583e-17 -141.216763014904 17.1489393082649 -8.23472288731261 1.40183837741202e-15 MED9 other 1.80911574074264e-44 2.11453300848829e-11 4.27736592833017e-13 8.73310639234783 -8.23472288731261 2.46656987038868e-40 479.765377341453 107.517094963533 4.46222414681293 9.88394335511431e-06 -2032.25187794174 194.300985858915 -10.4592978206369 1.96831778819109e-23 NCOR1 other 3.61821134287315e-36 3.05699435683958e-19 0.0891136332897106 4.46222414681293 -10.4592978206369 1.262096601831e-35 331.369060247521 30.6285120466601 10.8189735022944 8.34365069956753e-25 -122.518371079585 53.8062409573829 -2.27702900071807 0.0231784421640902 COPS3 essential 1.80871064008401e-31 1 1.19347579606614e-20 10.8189735022944 -2.27702900071807 2.27760120496225e-28 66.4639647830035 10.148943773908 6.54885535516277 1.38580281080841e-10 -116.48247643428 19.5530842750833 -5.95724310270146 4.70914594888866e-09 GID4 other 3.06815658320465e-24 6.49673775108679e-05 1.58965440427833e-06 6.54885535516277 -5.95724310270146 3.24477246814769e-51 26.4916826061524 2.50023452309934 10.595679069863 5.8217691191343e-24 -76.0777578862066 8.02658959332265 -9.47821699386449 8.10071753123242e-20 ZNF287 other 4.91939953895871e-47 1.24710546393323e-15 8.28845269491151e-20 10.595679069863 -9.47821699386449 0.227102892036203 -9.41415835162729 5.79390155755023 -1.6248391965444 0.104787971791175 -2.492575617594 10.1985379889414 -0.24440519026323 0.807011077503134 MYOCD other 1 1 1 -1.6248391965444 -0.24440519026323 0.0931109248206719 84.2377729334387 38.5661775302851 2.18423961947717 0.0294160066856352 103.462006921279 178.352753138994 0.580097616102674 0.562114354927443 KSR1 other 1 1 1 2.18423961947717 0.580097616102674 1.18225104720235e-59 282.305757858523 27.4623952861179 10.2797208661994 9.13865345722561e-23 -391.609523650544 60.8017283325924 -6.44076302417581 2.62435782533867e-10 UTP4 other 1.81522825787449e-55 3.7226515752429e-06 1.28791043172681e-18 10.2797208661994 -6.44076302417581 5.02800535623267e-42 123.072316431259 15.8612117717877 7.75932622311791 4.4314264684653e-14 -211.177691467521 35.549970143656 -5.94030573342706 5.16017982773813e-09 RANBP10 other 7.42787231276253e-38 7.11021178464037e-05 5.56542850174557e-10 7.75932622311791 -5.94030573342706 2.46367478113499e-40 19.838931898701 2.17871119975627 9.10581076597959 1.74100263038084e-18 -19.6443877973747 4.87610768039714 -4.02870262204193 6.42913442290361e-05 CTRL other 3.61421090392503e-36 0.735557269324402 2.35400965653793e-14 9.10581076597959 -4.02870262204193 1.27224642895239e-45 122.529095226248 16.7015307694636 7.33639909524194 8.36193571364057e-13 -261.46251020279 36.5586681847051 -7.15186091795808 2.88323805043755e-12 GFOD2 other 1.90328065771277e-41 4.21644732495987e-08 1.01764757635006e-08 7.33639909524194 -7.15186091795808 7.1151968925925e-34 149.249411575878 28.3812273070899 5.25873705040915 2.0882173362278e-07 -409.362991001159 62.0527205249887 -6.59701923683278 9.96045638600306e-11 NOB1 essential 1.00694266423969e-29 1.42404644950686e-06 0.00209531727517097 5.25873705040915 -6.59701923683278 4.84133270334006e-86 200.615486948378 9.69510929874818 20.6924420103527 2.7365074014816e-70 -66.5150547267211 24.9759335146668 -2.66316591080213 0.0079745591342426 PRPSAP2 other 7.54134395199281e-82 1 4.24733313783959e-66 20.6924420103527 -2.66316591080213 0.00869361507891371 158.984224994627 61.1005444046882 2.60200995823579 0.00954005112757626 513.763619051974 235.986166299534 2.17709210293225 0.0299360535829641 PCTP other 1 1 1 2.60200995823579 2.17709210293225 5.31547054174937e-41 414.198645435509 33.9569121435678 12.1977712132452 3.85784214681873e-30 -789.93747493642 130.68817350046 -6.04444498517414 2.93411116455385e-09 TOM1L1 other 7.81693097869662e-37 4.06609125183873e-05 5.67488579797036e-26 12.1977712132452 -6.04444498517414 1.19513091181579e-49 176.020911774155 11.1163027139877 15.8344834881716 1.71349609090428e-46 -84.7202510620205 36.8360911826265 -2.29992510991444 0.0218416310425594 C17orf80 other 1.80548426848011e-45 1 2.61548043315629e-42 15.8344834881716 -2.29992510991444 2.96384344419896e-41 1018.75911717275 87.1291051947356 11.6925235820545 3.52100698417495e-28 -2437.26212369392 361.812549538869 -6.73625645876633 4.34964687438032e-11 TOB1 other 4.36366670289412e-37 6.25305234660914e-07 5.13433238432391e-24 11.6925235820545 -6.73625645876633 1.30545813000065e-38 203.420147658463 26.4101933259281 7.7023346685901 6.57033246215915e-14 -362.88836206441 48.1992502905086 -7.52892129809477 2.20473216961925e-13 VPS53 other 1.89983321658994e-34 3.26168077173472e-09 8.21685777717624e-10 7.7023346685901 -7.52892129809477 1.06302978816086e-33 125.507002004011 60.289738690998 2.08173073443343 0.0378400852413892 -1205.31401327495 110.416755963091 -10.9160426129333 3.42461422628976e-25 SGSM2 other 1.50206109067129e-29 5.33280927317841e-21 1 2.08173073443343 -10.9160426129333 1.59640095650329e-35 647.48394538299 79.8942704434798 8.10426006506992 3.70126599034801e-15 -1546.17147065858 203.397371452279 -7.60172788674086 1.34037174641495e-13 NPEPPS other 2.28620580980837e-31 1.98736918840945e-09 4.74465287302711e-11 8.10426006506992 -7.60172788674086 2.7027094510099e-22 102.333652210826 15.1729367500632 6.74448552027345 4.04910288600973e-11 -354.775111375041 57.6283241857553 -6.15626285143192 1.47713608829484e-09 SKAP1 other 3.34838673885616e-18 2.06134341121545e-05 4.71477540046973e-07 6.74448552027345 -6.15626285143192 5.57626702450625e-30 40.3523218778484 6.35404561714467 6.35065032724482 4.60906803432432e-10 -144.211686523256 17.5514910355259 -8.21649204796091 1.61005913520167e-15 LRRC46 other 7.6266604094172e-26 2.42732515223004e-11 5.1985678359144e-06 6.35065032724482 -8.21649204796091 1.3430575280776e-18 83.450430306113 22.5287138787582 3.70418084029185 0.000234285776783224 -445.177590446867 62.230041065182 -7.15374090755575 2.81695886378124e-12 SCRN2 other 1.53780086964885e-14 4.12036573005281e-08 1 3.70418084029185 -7.15374090755575 1.36894005316735e-11 97.7396748649675 16.7289685822681 5.84254040434786 9.12285310398056e-09 -128.952685356935 62.2185021993292 -2.0725777831136 0.0387085013096607 SSH2 other 1.23204604785061e-07 1 9.77878624215677e-05 5.84254040434786 -2.0725777831136 0.00184619295049966 22.5829795686232 9.9432699714792 2.27118238098726 0.0235494522984937 -35.8443106492108 22.8204357679323 -1.57071105099492 0.116866328852257 RHBDL3 other 1 1 1 2.27118238098726 -1.57071105099492 1.63724332217646e-35 151.348228349364 16.6284411229439 9.10176890487555 1.84530661997794e-18 -759.265665247918 87.9699921441595 -8.63096206719768 7.28200267638318e-17 ARSG other 2.34420498869225e-31 1.10693722683701e-12 2.49393189690019e-14 9.10176890487555 -8.63096206719768 0.332663164291751 -27.8665036982884 21.2244749583216 -1.31294195748115 0.189773927607104 -83.3491539723203 90.7613495407122 -0.918333127417117 0.358864588675835 ABCA8 other 1 1 1 -1.31294195748115 -0.918333127417117 1.69890430670623e-50 389.275277286481 54.0217572869644 7.20589808322311 1.96390008108594e-12 -1424.1600957778 126.004566226257 -11.3024483035047 1.01561664441376e-26 G6PC3 other 2.57282068207592e-46 1.58466665027879e-22 2.37278407796803e-08 7.20589808322311 -11.3024483035047 4.04038212425147e-45 4717.07982826009 309.439101991795 15.2439681924399 2.13848697947709e-43 -1614.27617872872 1190.81547475316 -1.35560564416023 0.175834223285856 CLTC other 6.03592685541927e-41 1 3.25092790620108e-39 15.2439681924399 -1.35560564416023 4.71792057466903e-31 76.4139783176686 6.98986315718676 10.9321136335984 4.18902961037788e-25 -238.278847999533 48.1279443947315 -4.95094587970013 1.0096422069835e-06 BCAS3 other 6.5201662341926e-27 0.0128163981754485 6.00497394647669e-21 10.9321136335984 -4.95094587970013 8.07539018154616e-63 292.193562288654 15.3197175575025 19.0730384677072 2.25447069300423e-61 -45.8360780590556 58.9568238184304 -0.777451617818103 0.437259319518695 PTRH2 other 1.24417536527082e-58 1 3.48631347966175e-57 19.0730384677072 -0.777451617818103 3.33959091772491e-42 530.845337960801 51.5526459521789 10.297150188047 8.62851205899758e-23 -728.442795213343 117.441353074748 -6.20260901413247 1.11919357398377e-09 SS18 other 4.93658329458095e-38 1.56608756807548e-05 1.21662020031866e-18 10.297150188047 -6.20260901413247 2.79913233790765e-13 133.052766696257 17.6402922930135 7.54254886972327 2.00619806271574e-13 39.1735640248457 39.6433457388344 0.988149796511032 0.323528492358196 TAF4B other 2.70704088399049e-09 1 2.4814663837731e-09 7.54254886972327 0.988149796511032 3.56445407520208e-29 479.021431621056 51.922809998655 9.22564536922144 6.6363966340835e-19 -435.588927123043 123.553838391025 -3.52549894681933 0.000459222157619864 AFG3L2 essential 4.84124152493946e-25 1 9.01687210672925e-15 9.22564536922144 -3.52549894681933 1.73023345345546e-14 28.7145743548141 4.79668069709168 5.98634267488856 3.95375949274067e-09 -31.3445334550189 11.4437579877258 -2.73900701925348 0.00636959074405616 PRELID3A other 1.75168834827831e-10 1 4.29575968886273e-05 5.98634267488856 -2.73900701925348 4.88013592717372e-11 314.332013091912 45.0194966402239 6.98213077778093 8.68585193551115e-12 213.437899535896 106.145907839157 2.01079724956819 0.0448499707889034 IMPA2 other 4.27451105861146e-07 1 1.03248721957421e-07 6.98213077778093 2.01079724956819 9.83957826863638e-08 -3.09929261276263 15.6608381859255 -0.197900813223904 0.843198120694578 -192.956702711881 36.316664430606 -5.3131724991039 1.58569165731387e-07 GNAL other 0.000711862784659112 0.00208026888523007 1 -0.197900813223904 -5.3131724991039 2.14998536695928e-06 -886.5463688623 3280.8262861511 -0.270220454098577 0.787094089614566 -34570.1839690734 7093.74998480707 -4.87332990916138 1.44522078026881e-06 SLC39A6 other 0.0139362051486301 0.0182155627145081 1 -0.270220454098577 -4.87332990916138 3.26111079891067e-33 503.381441301826 51.5075233108242 9.77296924692243 7.01064244513179e-21 -485.181118979117 111.348323122379 -4.3573275768677 1.5763080758778e-05 RPRD1A other 4.59164400486623e-29 0.188116605775257 9.72095681441973e-17 9.77296924692243 -4.3573275768677 5.98427604960477e-20 86.8837361785839 10.8156352938283 8.03316068064557 5.99887322078273e-15 -49.6173990001634 23.3811058280473 -2.12211515422182 0.0342826735283771 C18orf21 other 7.0799969942874e-16 1 7.66356053954993e-11 8.03316068064557 -2.12211515422182 4.22488300505086e-07 397.306601203434 110.097420577997 3.60868219362113 0.000336316502078142 -581.066398090295 238.093401748419 -2.44049769469998 0.0149868356821305 GALNT1 other 0.00291390180858358 1 1 3.60868219362113 -2.44049769469998 0.0763649290375787 9.28652589238631 5.3579596904705 1.73322055947958 0.0836252128389896 -8.061259420641 11.5613333798244 -0.697260355341766 0.48593883992139 ASXL3 other 1 1 1 1.73322055947958 -0.697260355341766 0.548193092886131 -13.3918626463324 13.9802151972013 -0.957915343750448 0.338544687003402 0.967654950462782 30.7198349166442 0.0314993538568301 0.974883233114126 ADCYAP1 other 1 1 1 -0.957915343750448 0.0314993538568301 0.00927506411678835 26.5075697430646 17.4484164706054 1.51919630000355 0.129297261480481 -92.5222623980428 45.5272270145309 -2.03224023216948 0.0426173186972281 GAREM1 other 1 1 1 1.51919630000355 -2.03224023216948 2.54845536491055e-17 137.320066777251 20.4152134102815 6.72635960337765 4.72458372129672e-11 -145.248216356251 46.8087378832138 -3.10301501225349 0.00202290575538383 ESCO1 other 2.82572730861282e-13 1 5.4885489090304e-07 6.72635960337765 -3.10301501225349 6.19666534562809e-16 372.787153584693 67.9370377006366 5.487244751933 6.33490859702122e-08 -632.865225873539 154.76640401453 -4.08916411738897 5.00180650556248e-05 OSBPL1A other 6.59325192774829e-12 0.577109100765287 0.000654522756244233 5.487244751933 -4.08916411738897 0.00095633063308587 52.3613862734756 13.9527724008121 3.75275857509352 0.000194836430219032 49.6468376809149 31.5829922102214 1.57194851426545 0.116577819601357 GATA6 other 1 1 1 3.75275857509352 1.57194851426545 2.53117007099001e-07 -111.632803955527 44.0376084484594 -2.53494247050631 0.0115479224829805 -553.391090402382 99.2004243390327 -5.57851535504609 3.96379682303048e-08 GREB1L other 0.00177738762384918 0.000531743343809538 1 -2.53494247050631 -5.57851535504609 5.05400904997897e-29 134.946467974682 13.3777557457247 10.0873771759369 5.48490408766749e-22 -79.3526001090103 30.4090621494143 -2.60950501265422 0.00932653247975775 C18orf8 other 6.85424707358148e-25 1 7.67283232823805e-18 10.0873771759369 -2.60950501265422 4.71192326674165e-47 486.610033098726 46.3093248917513 10.5078196289016 1.21316208638371e-23 -593.68967484249 87.0578624402261 -6.81948371119401 2.43345058494272e-11 PELP1 essential 7.07212563105255e-43 3.5136592995988e-07 1.72208358162168e-19 10.5078196289016 -6.81948371119401 1.01290409096061e-11 264.410601697053 40.5554871380953 6.51972446531612 1.65901259844202e-10 -55.8381290369691 92.0193317844062 -0.606808677635187 0.544240706967491 NPC1 other 9.17792396819406e-08 1 1.89791041261767e-06 6.51972446531612 -0.606808677635187 0.596026273562839 -13.3267360164781 23.4268338840261 -0.568866287371642 0.569682524517369 -50.2827140409651 50.0542476782513 -1.00456437511922 0.315554924584334 SLC14A1 other 1 1 1 -0.568866287371642 -1.00456437511922 5.95886956650372e-08 116.162327274794 23.0483034228327 5.03995132065635 6.34221513155059e-07 -28.1613154953501 43.1348450367928 -0.652866968023862 0.514116837649237 ARRB2 other 0.000438811154877334 1 0.00617604909510397 5.03995132065635 -0.652866968023862 1.10694753365869e-05 13.2895060068758 4.61496665336201 2.87965374510222 0.00413732135363522 -20.4992458821233 8.74741478111066 -2.34346334260835 0.0194634673872303 ZMYND15 other 0.0670588815890435 1 1 2.87965374510222 -2.34346334260835 2.97493388716334e-42 76.5584238320994 8.22695914327809 9.30579847289653 3.23907182898542e-19 -97.9655821524617 14.7167478905445 -6.65674120947634 6.8513523987054e-11 WRAP53 other 4.398439752171e-38 9.81730285210497e-07 4.41550271727292e-15 9.30579847289653 -6.65674120947634 3.13702869407314e-32 264.797799597694 44.8933059208943 5.8983804860415 6.46024350825435e-09 -666.381752400613 84.1451132059625 -7.9194349738351 1.35506776710358e-14 MINK1 other 4.38054686840373e-28 2.02745239314037e-10 6.96801864800315e-05 5.8983804860415 -7.9194349738351 4.37125356598524e-27 134.111093551693 25.7220678796531 5.21385349650596 2.63019335043338e-07 -326.448125895358 45.9951274716175 -7.09745018310476 3.97631326847546e-12 SAT2 other 5.80808461312459e-23 5.80183869003254e-08 0.00262309182838721 5.21385349650596 -7.09745018310476 0.743493823409196 -6.24853490298739 11.316837619236 -0.552144964275738 0.581074555691923 5.2956629251634 20.5101255240295 0.25819748976958 0.79635161148063 ASGR1 other 1 1 1 -0.552144964275738 0.25819748976958 0.3737656998464 -12.2697000623176 10.1250456057002 -1.21181677003114 0.226109580484241 1.69943978602978 17.9092656437492 0.0948916510500769 0.924435894310684 PIK3R5 other 1 1 1 -1.21181677003114 0.0948916510500769 4.94697774407831e-16 334.66139903528 81.7957114278344 4.0914296506919 4.93661587375065e-05 -744.695744028553 146.208352728765 -5.09338714327805 4.85695768668606e-07 TP53 ts 5.27694115960833e-12 0.00625236163007097 0.419365518475117 4.0914296506919 -5.09338714327805 4.12013198322068e-27 25.8587696249872 8.34698476329888 3.09797733652114 0.00204962884889547 -267.556286949163 25.3274464030404 -10.5638872032928 7.64617152848639e-24 CCDC40 other 5.47565540570028e-23 1.18844444067264e-19 1 3.09797733652114 -10.5638872032928 1.72049672862149e-23 1339.83049572858 139.546542426392 9.60131632380152 3.13865706202127e-20 -1183.41455585128 392.629135295831 -3.01407727921063 0.00270121572673959 ARHGDIA other 2.17264326890322e-19 1 4.32601102858391e-16 9.60131632380152 -3.01407727921063 2.2791763791382e-08 211.078736382663 36.5968121849711 5.76768094761393 1.35798856101812e-08 -62.394516857918 107.958005501292 -0.577951737513078 0.563538970536043 TMC6 other 0.000172647610719719 1 0.000144625781748429 5.76768094761393 -0.577951737513078 2.40960027071215e-09 61.8355756118899 13.029044801355 4.7459791991397 2.65717685426825e-06 -135.623288264308 39.4814870590218 -3.43511094355593 0.000637596754924249 CARD14 other 1.93442709732771e-05 1 0.0249083758319105 4.7459791991397 -3.43511094355593 0.00103831000107135 20.3709327783863 7.18736657377803 2.83426934876349 0.00476626773631759 73.7774145361102 24.696152893326 2.98740515799317 0.00294237060606615 TTYH2 other 1 1 1 2.83426934876349 2.98740515799317 1.77531483578043e-06 62.0345520125602 12.1829540324527 5.09191382051626 4.96727854339685e-07 -4.16075067721377 34.7806060741426 -0.119628469623105 0.904823758062387 RAB40B other 0.0115928058776462 1 0.00487290025107231 5.09191382051626 -0.119628469623105 1.02558710027062e-36 611.106524516056 45.6996527404344 13.3722356269757 1.89818600764801e-35 -216.600815105141 138.353366383672 -1.56556230445798 0.118034756643209 EIF4A3 essential 1.47756333535988e-32 1 2.83987608604218e-31 13.3722356269757 -1.56556230445798 3.13392034193172e-35 595.941818251336 58.4353184574796 10.198315573226 2.07295472702169e-22 -1153.78976985383 166.59632478111 -6.92566160369853 1.26829607832526e-11 CSNK1D other 4.47868556065462e-31 1.83953663200295e-07 2.91105032315656e-18 10.198315573226 -6.92566160369853 5.90922619984974e-16 413.395485665313 53.7216423917926 7.69513863054325 6.96999636430335e-14 -376.179613493942 151.18276904823 -2.48824397027635 0.0131442031908655 ANAPC11 essential 6.29096221236003e-12 1 8.71249545537919e-10 7.69513863054325 -2.48824397027635 1.03369912398744e-21 592.73940270218 64.7978954188741 9.14751009844572 1.32386400887201e-18 -538.310341190081 184.988802304758 -2.90996176245979 0.00376987434464349 TBCD essential 1.26679827644661e-17 1 1.79237948161181e-14 9.14751009844572 -2.90996176245979 2.76364766007058e-32 258.142278805967 21.8060655294889 11.838095160123 8.67880002776521e-29 -179.839500890994 62.2532247259415 -2.88883831613068 0.00402824208236324 FN3KRP other 3.86026305158659e-28 1 1.26849341205816e-24 11.838095160123 -2.88883831613068 7.05620837397536e-27 281.301133994054 24.6898336234769 11.3933993352864 5.1460315556993e-27 316.81288039666 70.3798569164047 4.50147093610836 8.32553298861887e-06 NARF other 9.34877047467995e-23 0.101046993882867 7.45762893051943e-23 11.3933993352864 4.50147093610836 4.38743091372448e-33 211.137673643749 18.3757107599766 11.4900411963177 1.73233908367493e-27 -219.608451245056 54.4161663187689 -4.03572074443086 6.22993349002849e-05 RPTOR essential 6.1722378094276e-29 0.713389683943163 2.5163957529462e-23 11.4900411963177 -4.03572074443086 9.29372842213683e-44 656.959714561786 42.3493532679153 15.5128629805903 7.22533192372007e-45 266.338892152724 121.062923270628 2.20000380758477 0.0282466095858806 FOXK2 other 1.38197741637175e-39 1 1.10005678538638e-40 15.5128629805903 2.20000380758477 1.34190448969759e-31 161.578001040475 12.8053894222629 12.6179685531127 3.59675369808501e-32 199.057806446023 46.6302799087082 4.26885291779793 2.32109208787441e-05 TRIM65 other 1.8632343839451e-27 0.273656757160393 5.32823092834313e-28 12.6179685531127 4.26885291779793 5.06292346869455e-10 70.2842671747677 11.6352844199043 6.04061444811209 2.87328317243115e-09 -57.6288745590866 33.002759979488 -1.74618348874168 0.0813519575035026 CBX8 other 4.21437749534134e-06 1 3.13906186588103e-05 6.04061444811209 -1.74618348874168 0.00559639279029202 147.067877172498 45.4730440104285 3.23417709047079 0.00129684550640934 63.1459515642274 129.790716785515 0.486521325470286 0.626801007370454 SECTM1 other 1 1 1 3.23417709047079 0.486521325470286 6.59539525414626e-05 33.3866134225301 13.0781192992264 2.55286044259474 0.0109571175959435 -131.447190126529 43.6927219116102 -3.00844590072564 0.00274787667859326 RNF157 other 0.367231607750864 1 1 2.55286044259474 -3.00844590072564 1.16284725703367e-08 110.509741968964 18.427200657543 5.99709874672298 3.71622171968905e-09 -15.1591456081606 51.8626377704052 -0.292294149697317 0.770175900498291 CEP131 other 8.95624957367332e-05 1 4.04287760884972e-05 5.99709874672298 -0.292294149697317 0.000142546271400387 24.7999470326067 10.6495122071967 2.3287401854751 0.0202559103494482 119.45138974823 30.4028471234176 3.92895406352333 9.68595553816375e-05 ZNF750 other 0.758631256392857 1 1 2.3287401854751 3.92895406352333 4.05869383134761e-23 719.110604313079 67.9322745924805 10.5856988983066 7.65261643846616e-24 122.549212541623 193.937010352971 0.631902143477304 0.527729062130997 WDR45B other 5.09569010525692e-19 1 1.08820205754989e-19 10.5856988983066 0.631902143477304 7.58989052577497e-11 228.27181870688 56.2759523689619 4.05629419134947 5.72665609970608e-05 -779.675966556004 159.623235807864 -4.88447664032127 1.37116640134702e-06 CBX4 other 6.58954295447783e-07 0.0173057377802527 0.484016973547158 4.05629419134947 -4.88447664032127 8.13202379112214e-05 21.3205266132304 9.06377444885734 2.35227903491335 0.0190168037162641 -42.2509174493559 18.7317418167392 -2.25557867830526 0.0244964605280807 RNF165 other 0.447586589463363 1 1 2.35227903491335 -2.25557867830526 2.04871933535112e-35 343.865623822936 32.9398576458206 10.4391958071065 2.34751682574417e-23 -223.959079162606 67.0805121744178 -3.33866084057742 0.000900114502547533 DYM other 2.93233198468806e-31 1 3.32643134207949e-19 10.4391958071065 -3.33866084057742 0.697412766230815 13.7634447477657 39.5537492850763 0.347968144525776 0.727999206976031 -44.9265344594398 81.9503743589288 -0.548216342034866 0.5837690797899 MAPK4 other 1 1 1 0.347968144525776 -0.548216342034866 3.47182240510001e-07 19.9599044692507 5.25194253010668 3.80048036604187 0.000160790888918286 -20.4413293919333 10.7359040675506 -1.90401565283332 0.0574374233667332 ELAC1 other 0.00241326375378502 1 1 3.80048036604187 -1.90401565283332 5.09528823389204e-35 180.156046689627 26.7977560513592 6.72280344459997 4.53697025287118e-11 -427.561423650975 55.6892132235528 -7.67763448074977 7.62818519908373e-14 MBD1 other 7.27046678094056e-31 1.13415857539977e-09 5.27468161598804e-07 6.72280344459997 -7.67763448074977 1.24147478460153e-31 344.199357532854 47.3521088825688 7.26893406978881 1.26929752782972e-12 -596.853957998837 97.1302317721001 -6.1448834941448 1.54941855207032e-09 SMAD4 ts 1.72465677076844e-27 2.16128393828289e-05 1.53953097150467e-08 7.26893406978881 -6.1448834941448 0.71809269367821 14.343318853598 18.7323899981465 0.76569614742258 0.444191661916692 23.8454709305862 42.0131947385194 0.567570999515629 0.570562187928143 TNFRSF11A other 1 1 1 0.76569614742258 0.567570999515629 2.53225425746716e-21 208.389501799156 24.019806502032 8.67573607562271 4.82227482285413e-17 -79.4333204009844 54.1657781216645 -1.46648535580095 0.143097120268389 ZCCHC2 other 3.07795504995133e-17 1 6.39433641510458e-13 8.67573607562271 -1.46648535580095 7.61943546024191e-08 17.663925909812 4.41712385156719 3.99896550411301 7.25327297833715e-05 -19.0319528712967 8.93475891628347 -2.13010256344032 0.0336170934235271 FBXO15 other 0.000555761622470045 1 0.606953882827252 3.99896550411301 -2.13010256344032 0.0143642879481779 42.8005169670827 126.928214145505 0.337202545984127 0.736096712634081 -631.597675081385 255.448131531526 -2.47250849436507 0.0137272435808062 CBLN2 other 1 1 1 0.337202545984127 -2.47250849436507 5.91214458748293e-06 95.4629124351554 35.722927385061 2.6723149367394 0.00775892634525894 -210.618461010447 78.3472785921835 -2.6882677330347 0.0074024838202191 PMAIP1 other 0.0366257357194568 1 1 2.6723149367394 -2.6882677330347 1.45004501376444e-29 245.229660048161 30.1403249976903 8.13626462445091 2.85868471832387e-15 -362.786560632716 71.8516861152645 -5.04910295425405 6.09296740806717e-07 P3H4 other 1.97525131774992e-25 0.00781240281062373 3.67169465221517e-11 8.13626462445091 -5.04910295425405 1.08403190582798e-25 186.110674921355 20.9391556366679 8.88816522264369 9.48883527799616e-18 -132.988340817224 48.8081156474886 -2.72471778623288 0.006646242220799 NT5C3B other 1.41390281477144e-21 1 1.27112437384037e-13 8.88816522264369 -2.72471778623288 5.77092386020505e-73 485.800133301507 46.6626086604598 10.4109081606737 3.05606773426307e-23 -1373.88134078964 103.765581725877 -13.2402413010039 8.0206709902025e-35 RETREG3 other 8.94550907570385e-69 1.25667873074493e-30 4.32555827107594e-19 10.4109081606737 -13.2402413010039 2.42114509541706e-186 5496.12365203142 118.655190776742 46.3201282308227 1.11738636779798e-184 -3979.66706139064 2377.78481283419 -1.67368680290589 0.094806531259509 ERBB2 og 3.79466070804716e-182 1 1.75127965424978e-180 46.3201282308227 -1.67368680290589 5.51862494625149e-191 491.036699908547 10.2578914746145 47.8691650349128 8.68712483771572e-191 150.606518340336 204.878005728358 0.735103398751457 0.462614415312736 GRB7 other 8.65154832823846e-187 1 1.36188056080869e-186 47.8691650349128 0.735103398751457 1.6455985850039e-184 835.609483325386 18.1126360786646 46.1340624134592 3.84540962606388e-184 134.16270956526 361.996935298558 0.370618357458216 0.711075689112121 MIEN1 other 2.57898210241812e-180 1 6.02652596596731e-180 46.1340624134592 0.370618357458216 6.31715843274295e-19 61.1639161272511 6.53269679936537 9.36273609594019 2.54145007809133e-19 -53.1758074350966 130.707766212165 -0.406829746816893 0.684305063576749 PNMT other 7.28684225216899e-15 1 3.46958764661028e-15 9.36273609594019 -0.406829746816893 6.7736911919011e-05 -35.7346630057187 38.2414706728747 -0.934447927262008 0.350519475973271 1255.06403034283 302.780626549987 4.14512660418062 3.98280627957347e-05 STAC2 other 0.376820441005458 0.462244496807297 1 -0.934447927262008 4.14512660418062 1.17417747315463e-17 653.992171131159 398.462666361205 1.64128844768186 0.101342196152797 -12936.7879780248 1582.0418842842 -8.17727274261013 2.23636915002869e-15 IGFBP4 other 1.31343492147077e-13 3.36886648760322e-11 1 1.64128844768186 -8.17727274261013 3.6792418206788e-13 672.686561038103 139.560466527172 4.82003663198657 1.87192065984444e-06 -1193.36586252746 332.698961798808 -3.58692391486669 0.000365225075769096 FKBP10 other 3.53648723803647e-09 1 0.0177158571247678 4.82003663198657 -3.58692391486669 1.20376097821784e-23 423.477387718672 48.7736153288203 8.6825096902021 5.15245948883575e-17 -197.93849017072 100.400958508325 -1.97148008456818 0.049204880895071 TXNL4A essential 1.52384102232596e-19 1 6.82958505245179e-13 8.6825096902021 -1.97148008456818 2.50361261901629e-06 15.2141448234506 2.99680702628158 5.07678495479512 5.30743022021306e-07 22.9995992798682 10.6489622983856 2.1597972305109 0.0312319102116053 CACNA1A other 0.0161207616538459 1 0.00519597418558858 5.07678495479512 2.1597972305109 3.07369045618052e-08 166.459266458089 29.7109909111429 5.60261577797662 3.3855099654895e-08 -48.9198943523611 103.704076286017 -0.471725857886623 0.637315160529922 SAMD1 other 0.000230864890163719 1 0.000354293617888476 5.60261577797662 -0.471725857886623 1.47300619320986e-37 731.76010053079 54.2636539998301 13.4852713850247 6.15702210810199e-36 -57.8585655638824 189.297654638544 -0.305648612891486 0.759989773370856 BRD4 og 2.1330602683872e-33 1 9.22075630909354e-32 13.4852713850247 -0.305648612891486 2.11500010981281e-20 122.236819314543 19.9833689712914 6.11692750557484 1.82409892501323e-09 -177.975230805231 41.6750549291565 -4.27054580030599 2.30134992802406e-05 SLC39A3 other 2.52382963103962e-16 0.271444224010437 2.00869773622456e-05 6.11692750557484 -4.27054580030599 6.52915314698967e-39 324.52522989648 113.517298560985 2.85881741382468 0.00441558727987069 -3026.54512565264 257.3655901946 -11.7597116357482 1.33630438541715e-28 NFIC other 9.51558779642274e-35 2.08864375440701e-24 1 2.85881741382468 -11.7597116357482 3.05628066876085e-05 10.9426767241208 10.6494879183213 1.02753078909035 0.304646488230853 -65.2807805177041 19.1055619074602 -3.41684692833943 0.000682919723557024 TPGS1 other 0.177172590368066 1 1 1.02753078909035 -3.41684692833943 2.19605274010848e-05 447.374116272884 122.866883242849 3.64112854876151 0.000298830813841618 -178.365651234354 222.051346728183 -0.803263091453775 0.422192537256151 PLPP2 other 0.129105940590977 1 1 3.64112854876151 -0.803263091453775 3.2730798383022e-13 37.8977540297243 5.05702444232713 7.49408164068208 2.71601451602213e-13 -12.7241043424092 16.0004532091163 -0.795233995944537 0.426823589457652 PRDM15 other 3.153939732188e-09 1 3.34911749970688e-09 7.49408164068208 -0.795233995944537 3.03228001381774e-14 843.942370277806 109.799196830049 7.68623445929292 7.33818051653623e-14 -160.699375280616 312.040502335045 -0.514995246059659 0.606769844213926 PFKL other 3.04168008186057e-10 1 9.16685510125706e-10 7.68623445929292 -0.514995246059659 4.28917039162199e-09 245.501423223086 55.3750056679806 4.43343382563376 1.12163837153018e-05 -384.741097738692 144.514980503932 -2.66229214713297 0.00798983942492221 FEM1A other 3.39316269681216e-05 1 0.100678260228549 4.43343382563376 -2.66229214713297 0.984963653238923 1.52658830860553 10.7112818582425 0.142521532792155 0.886720552377636 -1.40537300705563 29.1522272240362 -0.0482080835970192 0.961568004002526 VAV1 other 1 1 1 0.142521532792155 -0.0482080835970192 1.2672314810651e-14 159.347832771721 23.3809998626453 6.81527024968266 2.51724941327663e-11 -216.718234698715 81.9653939218342 -2.6440211451358 0.00843053619013995 MVB12A other 1.28966147827995e-10 1 2.95223011189084e-07 6.81527024968266 -2.6440211451358 8.25527712901227e-17 267.805790395764 47.1553961476656 5.67921833499478 2.20141276622702e-08 -543.780078257657 122.741386351404 -4.43029115461376 1.13753170138306e-05 SH3GL1 other 9.01558815259431e-13 0.136856438993395 0.000232326205724628 5.67921833499478 -4.43029115461376 6.95055822969442e-15 82.9494885774152 14.3377920777166 5.78537393538666 1.22427634932227e-08 -130.77502155823 35.584441317621 -3.67506181679103 0.00026143473422706 DUS3L other 7.14725902759477e-11 1 0.000130622890727292 5.78537393538666 -3.67506181679103 7.62601051458876e-21 263.546909605565 48.7873767665347 5.40194876364706 9.84900760894533e-08 -764.615422459431 127.306500484394 -6.00609882095661 3.46751987344767e-09 DPP9 other 9.18934267007945e-17 4.79835400087689e-05 0.00100627310740594 5.40194876364706 -6.00609882095661 2.05459327956976e-25 162.29624367296 23.1267174114457 7.01769476340111 6.71369523074096e-12 -436.109576562993 73.7467116794789 -5.91361386333307 5.90514840154633e-09 CCDC97 other 2.6699439668009e-21 8.12371265600729e-05 8.00071060647401e-08 7.01769476340111 -5.91361386333307 8.41625393351732e-08 -15.1166654916545 6.05274654460201 -2.4974885996401 0.0128009066912523 -111.242971958334 19.3010597376354 -5.76356808747758 1.37805811003847e-08 TMEM91 other 0.000611945823506045 0.000187650172843939 1 -2.4974885996401 -5.76356808747758 2.11226725604694e-13 9.71635357484956 7.7002917477432 1.26181629127198 0.207559646343034 -248.958090472009 34.4201784352868 -7.23291109428947 1.62806370494745e-12 ZFP14 other 2.0522788659752e-09 2.38706700419395e-08 1 1.26181629127198 -7.23291109428947 3.98790279388993e-21 42.1839515318855 24.5598063600068 1.71760114528337 0.086445904750715 -382.882238612644 50.4342441846891 -7.59171163962599 1.4071858030809e-13 SIRT3 other 4.83054665423887e-17 2.08615295306744e-09 1 1.71760114528337 -7.59171163962599 8.92304146501144e-05 1238.76173153558 621.540121882466 1.99305191720163 0.0467603922121301 -2865.73870179622 1273.52558877843 -2.25024037761586 0.0248368851130895 IFITM3 other 0.487733446477525 1 1 1.99305191720163 -2.25024037761586 0.000658543957531644 14.7913752202578 255.339813357153 0.0579281978230658 0.953827330841351 -1699.94409650513 523.187119697694 -3.24920861485923 0.00122954582887222 PGGHG other 1 1 1 0.0579281978230658 -3.24920861485923 0.000267536146607513 58.9002957766787 14.5077775913389 4.05991168570451 5.6384117277022e-05 22.6693242156239 42.1235008651965 0.538163347062966 0.590686845473873 HUNK other 1 1 0.476953248046329 4.05991168570451 0.538163347062966 0.0141622781287144 -2091.21200955135 777.668303188957 -2.68907965128061 0.00738721099172963 -4678.29140561803 2846.19833751394 -1.64369831292374 0.10082274961851 COL6A1 other 1 1 1 -2.68907965128061 -1.64369831292374 5.15983827270548e-27 382.464781137112 38.1094889553227 10.0359462071373 7.7304308292939e-22 -455.717048511366 119.679532947839 -3.80781105412556 0.000156375343218757 IFNAR1 other 6.84762137170745e-23 1 1.08017309977724e-17 10.0359462071373 -3.80781105412556 5.68679969678118e-20 1306.76215824596 149.230055667953 8.7566955088028 2.64518891695802e-17 -926.53610051918 435.465434690891 -2.12769149215452 0.0338192889984465 SOD1 essential 6.73089612111021e-16 1 3.52074644847113e-13 8.7566955088028 -2.12769149215452 0.0274568046389217 -1889.28248199122 769.364235480537 -2.45564115780764 0.0143779397843709 -4328.90653038831 2815.81799213901 -1.53735310395538 0.124793663144338 COL6A2 other 1 1 1 -2.45564115780764 -1.53735310395538 0.300765869631151 51.8574633696644 65.9780783961671 0.785980201761635 0.432240561523971 -217.347090674012 193.816212705239 -1.1214082023394 0.262636754472124 SIK1 other 1 1 1 0.785980201761635 -1.1214082023394 8.86581743063545e-07 102.617348153691 19.236464849873 5.33452216686105 1.41440059435014e-07 57.5168764776418 54.6776403743169 1.05192682207732 0.293306243580397 TRPM2 other 0.00595516956815783 1 0.00143094908130404 5.33452216686105 1.05192682207732 2.4072958150077e-21 344.358733079453 51.382175177186 6.70191037829692 5.37369067010984e-11 -651.166180230464 130.46979952564 -4.99093416712499 8.21491281014958e-07 SCYL1 other 2.92751244063086e-17 0.0104740138329407 6.23401854639443e-07 6.70191037829692 -4.99093416712499 1.02168640903567e-15 163.300598336905 31.6506515288187 5.15947035681763 3.49274767950643e-07 -571.735899819431 99.7930625990166 -5.72921488657735 1.6840039158827e-08 TMEM50B other 1.08043337755522e-11 0.000228502491346124 0.00345991585131907 5.15947035681763 -5.72921488657735 0.00595552066503659 2930.30414986207 1124.92805339993 2.60488138864139 0.00947455420343911 -2814.74366209575 3159.79718824827 -0.890798837521653 0.37348152688853 APP other 1 1 1 2.60488138864139 -0.890798837521653 2.4004459474189e-09 418.769798586737 74.1960413744894 5.64409894152011 2.69618658643231e-08 -390.690413645243 224.006257589097 -1.74410490961329 0.0817151198830461 DOPEY2 other 1.92779814037212e-05 1 0.000283638828892679 5.64409894152011 -1.74410490961329 2.66888938667192e-22 304.639604211303 32.0439743225083 9.50692324070793 6.39743326784494e-20 -205.378240983169 99.4135341412996 -2.06589819743516 0.039314501625525 URB1 essential 3.3067539500865e-18 1 8.78943356669216e-16 9.50692324070793 -2.06589819743516 8.18011156756773e-25 1087.94733774374 154.007209324749 7.06426239728571 5.05017882538585e-12 -1639.21118117817 322.058477451491 -5.08979361186068 4.97166070525443e-07 AKT1 og 1.05466178440651e-20 0.00639803016159193 6.03900383939639e-08 7.06426239728571 -5.08979361186068 0.776955208834241 5.23442715660596 7.97433085929687 0.65640957830379 0.511842325847502 -16.8076882617976 62.3639557199903 -0.269509656142771 0.787641232375243 IL19 other 1 1 1 0.65640957830379 -0.269509656142771 0.284176881125657 -32.4856772073368 22.9487634142537 -1.41557419112002 0.157469308554397 -77.4066760703414 69.5222250063924 -1.11340907261274 0.266021803980625 EMP3 other 1 1 1 -1.41557419112002 -1.11340907261274 7.2295037315461e-12 390.711933643544 61.3936200127044 6.36404782064802 4.15443739788539e-10 -228.129890103563 176.322186034656 -1.29382407985076 0.196271227334139 SAE1 essential 6.60125985727475e-08 1 4.69576059082985e-06 6.36404782064802 -1.29382407985076 0.00020469566973725 33.55966115896 17.3954207586247 1.92922388165409 0.0542247885502057 -151.45740675145 52.6617084674275 -2.87604430542033 0.00418537453732333 LMTK3 other 1 1 1 1.92922388165409 -2.87604430542033 2.37121286512508e-13 65.0414737074657 10.2802891022636 6.32681367814301 5.23784854112512e-10 -66.8108852678485 30.1827043490567 -2.21354867659287 0.027274711400657 GEMIN7 other 2.2996022365983e-09 1 5.89362717847398e-06 6.32681367814301 -2.21354867659287 1.1480594488719e-10 83.3929627005658 18.4307263427931 4.52467044160603 7.42763947686687e-06 -225.91241377067 60.9351741371636 -3.70742214114539 0.000230759226990009 CBLC other 9.8698670819517e-07 1 0.0675766639605348 4.52467044160603 -3.70742214114539 6.25436746957886e-06 49.7065218293753 12.0670792919068 4.11918415607931 4.397443241736e-05 -90.1748685089939 53.412411819981 -1.68827554188932 0.0919346463823086 WTIP other 0.0386582453294669 1 0.375541652844254 4.11918415607931 -1.68827554188932 0.00287823730244403 8.48211235441849 6.69624901198228 1.2666960770486 0.20582035991491 -71.6522811635111 26.0410878062494 -2.75150875787593 0.00613520146613604 ADAMTS10 other 1 1 1 1.2666960770486 -2.75150875787593 1.48569472199959e-05 30.3917196141578 13.5983579789876 2.23495510716216 0.0258239716781885 -82.7473347003929 26.4417046253964 -3.12942512113673 0.00184505032719511 CAPN10 other 0.0890228277422157 1 1 2.23495510716216 -3.12942512113673 0.406510436831864 -10.3632882462223 13.3942151516868 -0.773713736031574 0.43944571109099 -56.0879562220196 43.9015053501442 -1.27758617329133 0.201955763221565 MYO1F other 1 1 1 -0.773713736031574 -1.27758617329133 1.69046042429261e-32 279.868485111733 22.8582808071136 12.2436366703762 1.91760666348134e-30 -183.331126114961 96.4496125684909 -1.90079691595208 0.0578844847334874 ERVK3-1 other 2.36732077817937e-28 1 2.82348405130992e-26 12.2436366703762 -1.90079691595208 0.002117058461184 4.57201572502534 1.3002887376579 3.51615421453279 0.000475673514461523 4.79084392342519 5.14570726941845 0.931037012520659 0.352261529028153 NLRP12 other 1 1 1 3.51615421453279 0.931037012520659 4.02226451136936e-27 168.388693032953 14.4551526759455 11.6490428574418 3.57298508416014e-28 68.7630460731197 65.6978237120404 1.04665637593285 0.295719517163068 ZNF787 other 5.3467962149633e-23 1 5.20941225270548e-24 11.6490428574418 1.04665637593285 7.6990018277681e-43 84.8267304535877 6.17926562122146 13.7276394402382 5.20779193197107e-37 -59.2255852058602 20.2268703539394 -2.92806470647722 0.00355441489961912 TIMM29 other 1.14114605091179e-38 1 7.81897880666136e-33 13.7276394402382 -2.92806470647722 0.000284445312591388 69.7361495647643 17.7595447237679 3.92668565830042 9.71511663532318e-05 117.034207714394 51.1152297451704 2.28961521444501 0.022424302992032 FBN3 other 1 1 0.80382875040664 3.92668565830042 2.28961521444501 6.4250933717101e-42 577.199882538545 41.0839859923467 14.0492668517136 1.90239518746386e-38 -230.151847454471 134.486502494856 -1.71133789030817 0.0875919343176971 CARM1 other 9.48986291001582e-38 1 2.86614858943305e-34 14.0492668517136 -1.71133789030817 1.74100291700868e-19 86.6170977047118 15.1791775059144 5.70631034988307 1.89676698275337e-08 -213.987173578415 39.9012629969665 -5.36291729900087 1.21184686598258e-07 EVI5L other 2.03975901756737e-15 0.00159830483154443 0.000200772785124444 5.70631034988307 -5.36291729900087 7.65611363385694e-05 3.73691103929233 7.47806831527163 0.499716087329778 0.617482002323621 -77.5105299465143 20.5094060518618 -3.77926741274295 0.000175111836207035 SLC47A1 other 0.422847155997919 1 1 0.499716087329778 -3.77926741274295 2.47617595214147e-34 492.340019916535 50.8111389625329 9.68960802629471 1.36511866242527e-20 -407.851447544195 94.9203912667954 -4.29677377116826 2.05261884784277e-05 PSMB6 essential 3.51616985204089e-30 0.243153228715454 1.88782259826791e-16 9.68960802629471 -4.29677377116826 0.531260468878105 -6.4887283599178 6.31557874040493 -1.02741627119699 0.304677768547274 6.60370168763091 25.8217766922836 0.255741569076628 0.798246358812321 SIGLEC10 other 1 1 1 -1.02741627119699 0.255741569076628 0.670595828281666 1.60060311593074 9.82301136891912 0.162944239380114 0.870622517345769 -29.1985008139363 35.4421334316724 -0.823835869537228 0.410391875740824 KLK3 other 1 1 1 0.162944239380114 -0.823835869537228 4.05541028345863e-15 74.371681540895 8.98955010120192 8.27312609681673 1.02088714907741e-15 22.5498747256471 31.5954801831781 0.713705713441031 0.475716949081254 ZNF473 other 4.20262167674818e-11 1 1.32113005962108e-11 8.27312609681673 0.713705713441031 0.0911541921247635 15.2803136368727 7.14050555814607 2.13994842696265 0.032802294004548 0.752691453681479 24.9955611573453 0.0301130048228699 0.975987952966425 FAM71E1 other 1 1 1 2.13994842696265 0.0301130048228699 5.226611312259e-07 2503.03742365372 537.530289737723 4.65655140080575 4.04583678499201e-06 -3151.73910471701 1935.61744818429 -1.62828616143831 0.104043181421313 RPS11 essential 0.00357134350966658 1 0.037448265281886 4.65655140080575 -1.62828616143831 0.000176338755956533 1714.85320716192 546.423545170357 3.13832231849982 0.00179126110725355 -3816.79094770855 1967.64157913134 -1.93977957580749 0.0529230081242829 RPL13A other 0.92666016255158 1 1 3.13832231849982 -1.93977957580749 0.00704173374527195 7.68077496274219 2.44022162457343 3.14757269806788 0.00173636105227952 2.98389371524115 8.88429248307775 0.335861715598027 0.737104406512503 CTU1 other 1 1 1 3.14757269806788 0.335861715598027 1.48764421329188e-08 161.54319034285 32.2245702400808 5.0130440573548 7.26758344198639e-07 -257.133352736197 118.294193277359 -2.17367687806372 0.0301615485842298 NOSIP other 0.000113849411643227 1 0.00705464324713619 5.0130440573548 -2.17367687806372 0.771217842927652 -13.1633157569341 45.222627419536 -0.291078084314216 0.771102545341363 93.6316631319971 164.206377154232 0.570207227969305 0.568772572322913 RCN3 other 1 1 1 -0.291078084314216 0.570207227969305 5.92745761079107e-13 75.9102703165582 9.85795556943926 7.70040702474744 6.49754049768619e-14 65.1064475943094 41.4724985883839 1.569870391473 0.117029926813771 ZNF614 other 5.6429396454731e-09 1 8.12712365450588e-10 7.70040702474744 1.569870391473 0.779138720510773 6.25561404674217 16.5463261591796 0.378066646732434 0.705529652636839 19.2959391179505 27.3425715619381 0.705710473290346 0.480672528826547 SLC2A5 other 1 1 1 0.378066646732434 0.705710473290346 1.29466630413492e-20 86.7245858552079 116.821374430603 0.742369162132448 0.458186486255412 -1613.02284150839 193.298011386913 -8.34474617682281 5.99987375797273e-16 RERE other 1.55126916561446e-16 9.07060914730318e-12 1 0.742369162132448 -8.34474617682281 2.6055746257781e-10 55.518739088205 17.1977810584993 3.22825013874492 0.00132098489327127 -141.215924136413 34.8678205347098 -4.0500358775174 5.86994798130651e-05 MMEL1 other 2.20301334609538e-06 0.673459131895296 1 3.22825013874492 -4.0500358775174 0.605224426403942 4.18734574651544 4.41444787123298 0.94855480654841 0.343272172691106 5.7768829008431 7.97747888895436 0.724148942448696 0.469288487589437 PRDM16 og 1 1 1 0.94855480654841 0.724148942448696 0.000339648359823652 155.272618161741 38.6633835204045 4.01601215475093 6.74486060399968e-05 116.713716565228 62.0642615631098 1.88053017349684 0.0605659470360911 PADI3 other 1 1 0.566414364189158 4.01601215475093 1.88053017349684 0.000103553017130757 6.48187301809267 4.99323597147593 1.29813072226521 0.194794536482599 -22.9605887984735 8.11057744442947 -2.83094378369365 0.00481340938273155 FHAD1 other 0.56130299609046 1 1 1.29813072226521 -2.83094378369365 0.00359938232056703 74.6020221128198 30.8273756298933 2.41999263928513 0.0158474752936273 -39.0632636069702 49.7221714852942 -0.785630684261719 0.432425921281315 EPHA2 other 1 1 1 2.41999263928513 -0.785630684261719 1.37003470585198e-05 189.937814810439 50.2381179093632 3.78075100570277 0.000173626794869638 -43.9201566517967 78.7980010877846 -0.557376532976612 0.577499036571888 ARHGEF19 other 0.0823390858217038 1 1 3.78075100570277 -0.557376532976612 0.00025343380296403 176.327990495983 69.9280610785229 2.52156269995792 0.0119685109975353 -163.06460279746 113.35513741128 -1.43852856184031 0.150860253502079 EFHD2 other 1 1 1 2.52156269995792 -1.43852856184031 3.10172724685365e-17 46.9796275664488 17.3166241306611 2.71297841957924 0.0068801624854351 -169.585846413476 28.0746078920585 -6.04054193973078 2.85545013874465e-09 PEX14 other 3.4311306804695e-13 3.95822498232784e-05 1 2.71297841957924 -6.04054193973078 3.90924625393558e-14 790.646792111016 137.445806884294 5.75242570169207 1.4704941072112e-08 -443.89628146844 222.695727603277 -1.99328602414512 0.0467300349697523 PGD essential 3.90416423380546e-10 1 0.000156430018996974 5.75242570169207 -1.99328602414512 0.628156931519591 -26.8533735305503 44.6679582234813 -0.601177546468509 0.547970324099487 -72.0918741979166 75.4525271236459 -0.955460034887605 0.339766394155923 MYOM3 other 1 1 1 -0.601177546468509 -0.955460034887605 1.10936905061442e-07 772.301094254483 166.076941155808 4.65026083018916 4.16463612162446e-06 -141.946992825702 272.92302103499 -0.52009900919096 0.603205762436201 SH3BGRL3 other 0.000799855085492994 1 0.0385187194889046 4.65026083018916 -0.52009900919096 1.96674572176880e-09 44.994078563059 30.2173477467483 1.48901481824793 0.137061884067579 -232.000538460787 50.1930643010055 -4.62216327478017 4.74608216448942e-06 CNKSR1 other 1.58775382118395e-05 0.0583720645410554 1 1.48901481824793 -4.62216327478017 4.29451561515001e-16 496.178736941715 744.335298592361 0.666606484846354 0.50530561821266 -8273.82150039221 1178.49237657588 -7.02068309040053 6.59576925193906e-12 RPL11 essential 4.59169609571839e-12 9.60146130004769e-08 1 0.666606484846354 -7.02068309040053 0.0187003740404776 8.83423314918499 3.21243503007469 2.75001146061453 0.00615616546626537 4.38830167056257 5.41937848841496 0.809742607928838 0.418439583727499 IL22RA1 other 1 1 1 2.75001146061453 0.809742607928838 8.30323235709317e-05 106.938574677984 34.0472369712461 3.14088848878682 0.00177575002858443 -56.4970433607795 56.5547700907412 -0.9989792774355 0.318248056111574 ZNF593 other 0.456096553375128 1 1 3.14088848878682 -0.9989792774355 1.14427844627628e-11 34.8265580059885 15.6028888251664 2.23205833203244 0.0260227937090209 -165.341784009884 30.1868690781446 -5.47727502252267 6.64541481492888e-08 C1orf216 other 1.03397000405524e-07 0.000884371803570736 1 2.23205833203244 -5.47727502252267 4.82277625288714e-09 341.51436960701 141.475148823011 2.41395306842373 0.0161133833863138 -1163.74195828363 268.209390515787 -4.33893069905443 1.71042803486372e-05 KIAA0319L other 3.80565274115324e-05 0.20369487467192 1 2.41395306842373 -4.33893069905443 0.00258648694128252 -168.391526350924 92.0134408707264 -1.83007531027456 0.0677897495871543 -630.908407479057 184.597470215679 -3.41775218664654 0.000679022140468742 EVA1B other 1 1 1 -1.83007531027456 -3.41775218664654 5.0106177744882e-09 99.5568029492028 15.8466576510136 6.28251112264262 6.8811236694778e-10 96.557199970118 33.1199180957295 2.91538160484063 0.00370058564571661 PLK4 essential 3.94786574451925e-05 1 7.70617039744818e-06 6.28251112264262 2.91538160484063 3.29801905488145e-13 37.1345484135685 45.2393166533504 0.820846802309476 0.41209845155569 -436.097783714932 70.7532193640749 -6.16364580487714 1.398749112927e-09 MAP3K6 other 3.1769817555673e-09 1.95349301111386e-05 1 0.820846802309476 -6.16364580487714 0.607806238186737 1.52590360658417 5.99842961563169 0.254383847833726 0.799296408006238 -6.46123595964549 9.39227545622753 -0.687930841653646 0.491793370480908 FCN3 other 1 1 1 0.254383847833726 -0.687930841653646 3.20233097412804e-26 31.7704661985019 16.7392308317163 1.89796451927203 0.0582298366367827 -221.54412947291 25.9618097559166 -8.53346248030418 1.41889233747401e-16 GPN2 essential 4.206902200712e-22 2.15302723288306e-12 1 1.89796451927203 -8.53346248030418 7.33378967487888e-05 10.1552937537215 52.0726738050936 0.195021553756438 0.845449699742836 -296.053908435936 81.4011432739167 -3.63697482036226 0.000302398647717362 SYTL1 other 0.405998596401295 1 1 0.195021553756438 -3.63697482036226 1.88168808184044e-28 50.1016998583719 73.2035715641419 0.684416057684729 0.494005019567836 -1112.49425616275 113.554762152474 -9.79698460086567 5.65690872807079e-21 WDTC1 other 2.53632736551273e-24 8.73822691225095e-17 1 0.684416057684729 -9.79698460086567 3.34134234822948e-09 32.0933432067712 17.5578345024512 1.827864546866 0.068114426886714 -124.660698403632 29.1422872444165 -4.27765663546251 2.22939827557403e-05 NBPF3 other 2.66037677766031e-05 0.263336524310804 1 1.827864546866 -4.27765663546251 0.00291298867335068 -1270.71742636402 497.385691169595 -2.55479288794164 0.0108952092235224 -2722.36601697955 831.055830533373 -3.27579197083827 0.00112051819853862 HSPG2 other 1 1 1 -2.55479288794164 -3.27579197083827 3.54656092467336e-17 85.2708053840377 12.6558756102501 6.73764566040582 4.13626164441061e-11 -80.7218955819198 24.9310401333821 -3.23780697275582 0.00127848221202149 ITGB3BP other 3.91611257302433e-13 1 4.81502218025839e-07 6.73764566040582 -3.23780697275582 5.70471698786213e-19 1415.06799034367 188.370905625252 7.51213668398889 2.43885006751609e-13 -1059.19386478292 362.791336035773 -2.91956769518464 0.00365202037168643 SERBP1 essential 6.58894812098076e-15 1 3.01051652334186e-09 7.51213668398889 -2.91956769518464 2.764615977216e-16 68.4819641725617 16.4179967157549 4.17115226407894 3.53077024048275e-05 -162.388534879536 31.110849543418 -5.21967536286363 2.56076877571338e-07 BCL10 other 2.97445032988669e-12 0.00333002371593768 0.304140548515184 4.17115226407894 -5.21967536286363 0.00782903735675266 -254.637894790939 383.20557578538 -0.664494232029526 0.506656640687256 -2241.99078028764 731.970214576299 -3.06295356783802 0.00230050034121625 CYR61 other 1 1 1 -0.664494232029526 -3.06295356783802 0.844841930199093 -162.627811148943 452.423515059654 -0.35945923617056 0.719391828993199 225.651695923157 863.353262627126 0.261366587341679 0.793909291006298 PRKACB other 1 1 1 -0.35945923617056 0.261366587341679 5.01012109003155e-06 22.6681854641742 42.4430752055757 0.534084426125567 0.593503733832841 -370.021855874726 84.3910017010808 -4.38461267689855 1.39803191492126e-05 PIGK other 0.0312681657228869 0.167344420216075 1 0.534084426125567 -4.38461267689855 0.132582569752395 171.681280409281 88.532148269632 1.93919704609913 0.0530027533431244 56.1754631872734 159.002497983166 0.353299249381735 0.724003274942976 TINAGL1 other 1 1 1 1.93919704609913 0.353299249381735 9.2616677694078e-08 -23.1782380490968 11.2874459145843 -2.05345285589796 0.0405088633041239 -121.137804360365 21.0076331764767 -5.76637088732155 1.36287330481242e-08 AZIN2 other 0.000670544746505124 0.000185636972848499 1 -2.05345285589796 -5.76637088732155 7.14670753190473e-12 1009.48943424654 666.63863738965 1.51429781837936 0.130531091922612 -8867.64609804334 1406.76699202884 -6.3035642350795 6.01752898551243e-10 RPS8 essential 6.52994667190135e-08 8.47328256450005e-06 1 1.51429781837936 -6.3035642350795 4.49012308644467e-17 447.812468638384 51.6209716336207 8.67501045537708 4.78929363226467e-17 64.0991195205482 108.932598438918 0.588429179503052 0.556488475501659 KIF2C other 4.94497255510151e-13 1 6.3515612151094e-13 8.67501045537708 0.588429179503052 2.21515328464632e-14 3230.93808621535 597.768056497833 5.40500291224086 9.73998143201623e-08 -5346.54331491081 1329.53386883166 -4.02136676639094 6.61024195948459e-05 PTPRF other 2.2322099649381e-10 0.755220143871115 0.000995718301795019 5.40500291224086 -4.02136676639094 2.70144603573249e-07 2.20274693664833 13.5979127396571 0.1619915481752 0.871372768524076 -144.430475188251 28.1422286656319 -5.13216195150293 3.99523782186017e-07 MOB3C other 0.00189128236961632 0.00515825155180366 1 0.1619915481752 -5.13216195150293 0.407721434944233 -105.347986991938 127.740309932647 -0.824704332152353 0.409902266319651 -344.501261506423 268.265175558387 -1.28418182042956 0.199626993777373 CYP4B1 other 1 1 1 -0.824704332152353 -1.28418182042956 0.00763489530997836 19.5033573737876 6.2267353539997 3.13219628986796 0.00182872715220745 16.5819900070087 14.0665197382077 1.17882676849829 0.238984402257501 TMEM61 other 1 1 1 3.13219628986796 1.17882676849829 1.79121055756161e-11 1421.29093128934 199.235368381883 7.13372802646712 3.13206905876474e-12 774.365226701626 392.178513238152 1.97452231716578 0.0488276910030682 LMO4 other 1.60259608585037e-07 1 3.76474700863521e-08 7.13372802646712 1.97452231716578 0.731248499156476 -19.0339342317862 31.797643216939 -0.598595754469206 0.549694422187784 -51.4246641085819 71.6353431069402 -0.717867213001451 0.473150760872857 SYPL2 other 1 1 1 -0.598595754469206 -0.717867213001451 2.38118914475228e-20 123.838542488327 17.3596788802199 7.13368855166046 3.17803147705903e-12 -113.086620569523 32.9485940203924 -3.43221384498324 0.000644821269633095 MTF2 other 2.83885369837367e-16 1 3.81904042598183e-08 7.13368855166046 -3.43221384498324 4.42146569531146e-08 11.087765527 16.8984829451519 0.656139699817316 0.512013202477027 -172.550779670458 33.9846984574203 -5.07730795041917 5.27509484291349e-07 SLC44A3 other 0.000327984325278204 0.006780606911081 1 0.656139699817316 -5.07730795041917 3.32405757542404e-25 865.353138561855 80.3613510189485 10.7682751420868 1.30068097581939e-24 57.344565053925 264.743999299243 0.216603833158491 0.82859951218972 IGSF3 other 4.30531937168922e-21 1 1.85828291015317e-20 10.7682751420868 0.216603833158491 2.02446788894989e-05 26.0855745721273 6.69843376619455 3.8942796902427 0.000111727834142806 -44.6849149348006 25.7290346545652 -1.73675054407344 0.0830409940995649 ZNF697 other 0.119666296915828 1 0.91862625232215 3.8942796902427 -1.73675054407344 0.00143362569120411 84.6891636056613 31.6926813134062 2.67219938787057 0.00776156343022175 -78.7610158890426 69.9488797825919 -1.12597966020099 0.260670611326308 CTTNBP2NL other 1 1 1 2.67219938787057 -1.12597966020099 2.65987522309481e-24 79.2533270073897 17.997698994859 4.40352553012629 1.28319471655376e-05 -281.967829843744 38.8514117561579 -7.25759546688938 1.37011541576529e-12 STRIP1 essential 3.40224639786057e-20 2.00995931492768e-08 0.114589288188251 4.40352553012629 -7.25759546688938 5.7286169127489e-41 802.413570198222 61.3299292471666 13.0835561046289 3.58300040643185e-34 -206.62191101866 148.115509633324 -1.39500523294403 0.163587755143255 PSMA5 essential 8.42335830850598e-37 1 5.34225360598988e-30 13.0835561046289 -1.39500523294403 0.510212524383966 3.69656318321875 14.4167153285645 0.256408141450541 0.797732282949095 -29.9165659971685 32.4805284364923 -0.92106155402191 0.357425067765681 C1orf162 other 1 1 1 0.256408141450541 -0.92106155402191 0.584022538526076 39.5028346545911 45.8844233532553 0.860920368345188 0.389661884771743 -16.5063768931912 98.5242330011231 -0.167536213075651 0.86701053171753 CD53 other 1 1 1 0.860920368345188 -0.167536213075651 0.00222235426077044 313.35790981354 308.587606297833 1.0154585064933 0.310345461596743 -2018.06842757425 745.043583705678 -2.70865822041824 0.00697155721946695 CELSR2 other 1 1 1 1.0154585064933 -2.70865822041824 0.00462708806428091 78.1694251507102 23.7210539328162 3.29536054224678 0.00104747052211269 33.4024878420619 192.821788942199 0.173229841011769 0.862535681324897 GPR161 other 1 1 1 3.29536054224678 0.173229841011769 7.02071457579643e-08 417.09280287793 73.1866674020927 5.6990271272552 1.98886537526438e-08 -659.699956325352 610.333670242438 -1.08088409420916 0.280233850818842 ALDH9A1 other 0.000513495064073751 1 0.000210382179395466 5.6990271272552 -1.08088409420916 0.0870934347211226 409.102619386682 200.6648052024 2.03873628449215 0.0419619660636828 -1062.98796919915 1502.81956804566 -0.707329071168213 0.47966657642867 ATP1B1 other 1 1 1 2.03873628449215 -0.707329071168213 1.18147809840163e-26 239.048203305522 20.8900836296675 11.4431424757933 2.70836309228572e-27 -174.109045492664 173.639464784049 -1.00270434321598 0.31645346218778 TIPRL essential 1.56061442017872e-22 1 3.92983484690658e-23 11.4431424757933 -1.00270434321598 4.16879125450623e-07 89.4239364274753 17.3377422907982 5.15776131214824 3.50604254672441e-07 -195.842072571821 130.131122417618 -1.50495952800071 0.13291484811206 NME7 other 0.00287771660298565 1 0.00347238453827586 5.15776131214824 -1.50495952800071 3.3125915568817e-22 491.470323215888 47.9364819046944 10.2525321777475 1.21117411336759e-22 -598.096379818534 398.50209651115 -1.50086131303904 0.133980253868828 POGK other 4.0966819783956e-18 1 1.70436421233087e-18 10.2525321777475 -1.50086131303904 1.20154193193882e-05 259.054834712627 56.093862090743 4.6182385212406 4.84296737977617e-06 -529.167802577249 465.394623736585 -1.13703032993514 0.256029897312065 MPC2 other 0.0725370864311467 1 0.0446037295677385 4.6182385212406 -1.13703032993514 9.02905220805812e-11 349.048210081037 51.254029083249 6.81016139266042 2.60995141197339e-11 -455.68543474465 419.788912920315 -1.08551088587504 0.278180696239141 CREG1 other 7.80380982342463e-07 1 3.05886305483281e-07 6.81016139266042 -1.08551088587504 1.70787530019365e-13 420.504367797065 55.4154322916825 7.58821776547217 1.43073815715701e-13 -821.836490957038 460.096620805579 -1.78622587907317 0.0746236438622404 DCAF6 other 1.66586156780889e-09 1 1.77540297921614e-09 7.58821776547217 -1.78622587907317 2.26663010902849e-06 18.4832397966912 3.59298337509583 5.14425976051119 3.7664948038545e-07 -3.558117404401 29.8396307139675 -0.119241335072404 0.905128587941332 TBX19 other 0.0146560302849782 1 0.00372355676309055 5.14425976051119 -0.119241335072404 3.6678383107055e-17 476.277681054752 53.4738046240525 8.90674760105853 8.0876179482725e-18 -523.983161166348 446.071402030833 -1.17466208051179 0.240649588641391 TMCO1 other 4.04892671118781e-13 1 1.08503482394024e-13 8.90674760105853 -1.17466208051179 0.994412588612212 -0.0334884785608879 0.766067022407397 -0.0437148155205128 0.965147888940495 0.552496163899656 5.95656868469239 0.0927540994061732 0.926133318043183 XCL1 other 1 1 1 -0.0437148155205128 0.0927540994061732 0.408463957871525 -0.704529424246032 0.550848044931052 -1.27899051422469 0.201449737683855 1.37613935363817 4.4852916849071 0.306811563285582 0.759105077498792 XCL2 other 1 1 1 -1.27899051422469 0.306811563285582 0.0885126438901239 29.8395143876677 16.6648674315159 1.79056416201887 0.0739243419514158 -164.989523846802 138.226575115103 -1.19361652207192 0.233153089628443 POU2F1 other 1 1 1 1.79056416201887 -1.19361652207192 1.2735550308211e-07 10.4572980064872 17.7744039732827 0.588334664960122 0.556555037055759 839.94801268268 147.198033152022 5.7062448097741 1.91100476902983e-08 MAEL other 0.000914921934141881 0.000258883816060471 1 0.588334664960122 5.7062448097741 0.099930348734185 3.77105863397123 2.08881078005021 1.80536153393491 0.0715780595626689 21.4308773183337 17.3670492473348 1.23399646152455 0.217744001664727 ILDR2 other 1 1 1 1.80536153393491 1.23399646152455 0.0606391869567002 240.238419662237 117.315953497211 2.04778985722474 0.0410628792030558 -949.735145881133 913.098184949392 -1.04012379121504 0.298747003953303 DPT other 1 1 1 2.04778985722474 -1.04012379121504 2.16097406106552e-11 410.539156660657 61.7319009302627 6.65035663043059 7.21101671434551e-11 1479.23727989613 518.326035971352 2.85387415880821 0.00448568887708962 MGST3 other 1.92715666765823e-07 1 8.33881972846915e-07 6.65035663043059 2.85387415880821 1.34717410896241e-29 218.882111460969 17.8422369222269 12.2676384365403 1.057457362092e-30 59.8289098607027 124.699590226574 0.47978433411045 0.631574303096318 RFWD2 other 1.83579415828307e-25 1 1.55879789745981e-26 12.2676384365403 0.47978433411045 7.9801730291119e-26 474.583916592642 42.8782387058738 11.0681765603313 8.56223478475913e-26 1175.76608302447 485.440243723578 2.42206141379161 0.0157621703322865 NECTIN4 other 1.04340762355638e-21 1 1.23193434083114e-21 11.0681765603313 2.42206141379161 1.33542577737786e-34 610.811617900175 45.4172917516697 13.4488780449512 9.2543796446489e-36 -182.484208261618 513.954372408195 -0.355059161004053 0.722684160238348 UFC1 other 1.89977671089775e-30 1 1.38538063280394e-31 13.4488780449512 -0.355059161004053 8.54786063894305e-27 103.156611700431 8.95799116068028 11.5155965048527 1.36562848827022e-27 121.517799941688 100.11850666923 1.21373963699994 0.225377748107152 PPOX other 1.13148031277689e-22 1 1.98466788200311e-23 11.5155965048527 1.21373963699994 7.97683827236027e-11 104.855415824102 15.1673518054779 6.91323160225189 1.35902585652174e-11 93.2439313457539 139.943203980439 0.66629838887201 0.505508680410505 NUF2 essential 6.91831183361807e-07 1 1.6060967572374e-07 6.91323160225189 0.66629838887201 0.234504391320988 -241.536287508725 178.380624430518 -1.35405001681002 0.176294231020221 -1633.0138346127 1647.5991786735 -0.991147516793172 0.322063286132335 RGS5 other 1 1 1 -1.35405001681002 -0.991147516793172 7.0134354364248e-60 626.655359885625 33.3008565774623 18.8179952196707 4.49513137321993e-61 120.435981703383 365.816786216883 0.329224864033384 0.742113856435415 SDHC ts 1.07740395174358e-55 1 6.95037212927265e-57 18.8179952196707 0.329224864033384 9.25003335289022e-25 245.938797881464 22.2998923411447 11.0286988887247 1.23743304079307e-25 256.097413227766 252.139740431321 1.01569634675468 0.310231406276785 PFDN2 essential 1.19131179551873e-20 1 1.77806753631556e-21 11.0286988887247 1.01569634675468 2.7025460277703e-37 36.6438394710002 2.63569711044718 13.9029023197522 8.61625531604691e-38 55.4200388660266 29.4500688879885 1.88183053414284 0.0603956180639247 NR1I3 other 3.90707079234752e-33 1 1.29588479953345e-33 13.9029023197522 1.88183053414284 2.69631179456076e-32 161.59710716582 12.5372640382955 12.8893438530302 2.56055098198222e-33 102.234962649956 140.056420348967 0.72995555930407 0.465735057429516 USP21 other 3.76647794582192e-28 1 3.80728325510936e-29 12.8893438530302 0.72995555930407 3.12632716103859e-28 339.017755905462 28.4003040162882 11.9371171418104 2.48591488837178e-29 150.576776855436 253.837477424634 0.593201517692133 0.55329328516915 PRCC other 4.205222664313e-24 1 3.64285967742e-25 11.9371171418104 0.593201517692133 0.130362725986668 -2.85941721562166 3.86950321037742 -0.738962357739654 0.460249741604178 67.6033708148687 35.919468783229 1.8820815870872 0.0603604682949985 FCRL5 other 1 1 1 -0.738962357739654 1.8820815870872 1.59581789393967e-12 136.140433933743 18.2848945685356 7.44551375035059 3.82306606107791e-13 231.838173832501 163.27647336709 1.41991169365391 0.156208309126473 RRNAD1 other 1.49623885735783e-08 1 4.69281358997314e-09 7.44551375035059 1.41991169365391 6.42958770527602e-18 393.462269130803 42.6269882507803 9.23035582096514 6.02771565859322e-19 135.339780015972 380.641205545939 0.355557354390626 0.72231041919432 MRPL24 other 7.2442164675345e-14 1 8.19226835159404e-15 9.23035582096514 0.355557354390626 1.12130781897743e-22 134.405966204036 12.7502589037984 10.5414303519746 9.2452621511848e-24 -25.9461337642089 125.441427289707 -0.206838636364414 0.836213561685533 PIGM other 1.39815871948295e-18 1 1.31384420430487e-19 10.5414303519746 -0.206838636364414 0.982854105808825 4.92225293600956 82.9323530240782 0.0593526260442707 0.952693162591825 -139.845515494787 792.700152289349 -0.176416662833869 0.860032634342888 CASQ1 other 1 1 1 0.0593526260442707 -0.176416662833869 6.30204952374905e-26 261.00991253261 22.9455537315134 11.3751847345545 4.91767074970716e-27 7.40298791467721 204.894213564865 0.0361307807862207 0.971191381555631 ISG20L2 essential 8.25568487611125e-22 1 7.12718021755058e-23 11.3751847345545 0.0361307807862207 0.000428697654569329 2203.46660973466 562.311229220564 3.91858902193532 0.000100466513590501 3392.39917822589 5016.31255277445 0.676273486258268 0.499155496853925 CRABP2 other 1 1 0.830154801798306 3.91858902193532 0.676273486258268 2.48385827236224e-15 1430.91620275393 169.654583971582 8.43429142470804 3.03565122346497e-16 1234.9508908685 1514.94459306905 0.815178915795642 0.415327962134738 HDGF other 2.59140933555552e-11 1 3.96729258394637e-12 8.43429142470804 0.815178915795642 2.91981931433543e-09 145.821680079505 22.928684128652 6.35979279322374 4.29107336498406e-10 -6.63309902907788 157.314341452251 -0.0421646174649067 0.96638296798327 ABL2 other 2.33147572249684e-05 1 4.84805468775899e-06 6.35979279322374 -0.0421646174649067 8.42219708757485e-06 166.510932490336 35.0955485238029 4.74450292114405 2.67822853258861e-06 -238.130281465056 249.192170825389 -0.955609001182932 0.339696617637232 XPR1 other 0.0515185795846953 1 0.0250976795788879 4.74450292114405 -0.955609001182932 0.289857176575708 34.1857208350192 25.749126884186 1.32764582615866 0.184854029530104 163.960888066133 182.647179343423 0.897691870498836 0.369748425686712 RGS16 other 1 1 1 1.32764582615866 0.897691870498836 8.29878811249178e-12 260.7235002917 36.8813824462919 7.06924423647558 4.8290175131401e-12 -352.057157561558 259.227378871415 -1.35810175257834 0.174997500639452 TOR1AIP1 other 7.55604657642377e-08 1 5.77840235622345e-08 7.06924423647558 -1.35810175257834 0.153793111163811 6.67286967275084 36.496714905083 0.182834802806362 0.854997425006575 -487.266486867685 254.923181141738 -1.91142478563675 0.0564880346026617 HMCN1 other 1 1 1 0.182834802806362 -1.91142478563675 0.0644606980227443 32.1086080730664 14.4739830487271 2.21836711877938 0.0269434341562056 -62.653049968326 103.052733226605 -0.607970773861542 0.543461520104685 RGL1 other 1 1 1 2.21836711877938 -0.607970773861542 6.15458306603709e-22 84.3433799899021 8.39985545936765 10.0410513487873 7.67217011839669e-22 -74.1596190749588 52.1533319994316 -1.4219536169955 0.15562570534716 LYPLAL1 other 7.57444537937185e-18 1 1.07210905234475e-17 10.0410513487873 -1.4219536169955 1.24226889697271e-23 201.075086943636 18.6170614591396 10.8005813583928 1.04051577530742e-24 -209.351359773463 229.152968809936 -0.913587813680491 0.361349663994337 PRUNE1 other 1.57233974289836e-19 1 1.4872091976469e-20 10.8005813583928 -0.913587813680491 0.000138066392052471 65.5705882104576 22.8122134779583 2.87436325606077 0.00420591043243313 848.987718787146 289.542603278041 2.9321685623303 0.00350693515080865 RORC other 0.736998400776092 1 1 2.87436325606077 2.9321685623303 9.16252976482235e-08 199.362661326739 35.2328389369889 5.65843307952796 2.47914385226208e-08 345.938777944916 430.571615979273 0.803440740416964 0.4220728910888 TUFT1 other 0.000663733656163731 1 0.000261202596274333 5.65843307952796 0.803440740416964 3.80725749732278e-28 401.193095477386 33.6496268529986 11.9226610514891 4.70242379388655e-29 126.867772194305 401.580125991949 0.315921441283796 0.752192404451299 SF3B4 essential 5.11695407640182e-24 1 6.88011625283541e-25 11.9226610514891 0.315921441283796 0.329230689891678 357.900596242597 242.72857062806 1.474488954129 0.140956301591599 -967.880579125155 2966.41444189084 -0.326279620762706 0.744344330064117 ECM1 other 1 1 1 1.474488954129 -0.326279620762706 6.58926437482225e-24 221.863553955204 20.6254739245147 10.756773626981 1.45451958234207e-24 190.763506112531 242.57341716667 0.786415545201555 0.431972267639611 ZNF687 other 8.37297824108663e-20 1 2.07734486750094e-20 10.756773626981 0.786415545201555 0.0512390953225267 115.372249546347 59.0755307835046 1.95296170878522 0.051340279024346 966.75826066784 721.958176834457 1.33907792956477 0.181108687777712 CGN other 1 1 1 1.95296170878522 1.33907792956477 7.32456152896756e-29 287.776561465723 23.8168966713785 12.0828739964075 6.1760302745256e-30 -62.0555192230097 291.102738263826 -0.213173945367593 0.831271299609943 SNX27 other 9.91892122252787e-25 1 9.07567648841537e-26 12.0828739964075 -0.213173945367593 4.09372866653903e-32 227.659020182966 17.6893814673519 12.8698123562512 3.74624925871189e-33 18.1276826116827 217.701675415423 0.0832684570621287 0.933669699299306 SETDB1 other 5.71238898128857e-28 1 5.56692639844587e-29 12.8698123562512 0.0832684570621287 1.77604509336585e-05 59.5051694134507 12.6254009290351 4.71313107186993 3.14060925046061e-06 4.66170265414551 149.161539478904 0.0312527121296225 0.975080063234418 ADAMTSL4 other 0.105639162153401 1 0.0292893218697957 4.71313107186993 0.0312527121296225 1.54739658650538e-14 1083.28958951786 132.549883161572 8.17269365826135 2.33827478538245e-15 565.660250204934 1565.997368421 0.361214049021865 0.718086999692325 MCL1 essential 1.56998857666836e-10 1 3.00819051139452e-11 8.17269365826135 0.361214049021865 0.488230916054507 -348.678870620461 334.873755560628 -1.04122483422662 0.298254139808215 -1995.96389668351 3832.30979829547 -0.520825299032784 0.602709753161525 CTSK other 1 1 1 -1.04122483422662 -0.520825299032784 3.88366389937395e-08 132.52813398842 25.2676740101365 5.24496769806571 2.25245438927616e-07 741.661745507046 306.454482212462 2.42013672031352 0.0158455388755352 RFX5 other 0.000289721326893297 1 0.00225560782542115 5.24496769806571 2.42013672031352 2.1386927236795e-32 354.310251354314 27.8176855013361 12.7368702668414 1.1922953656659e-32 467.856483844162 329.666854954959 1.41917962577125 0.156427908458493 PI4KB other 2.99117564333814e-28 1 1.7686509454288e-28 12.7368702668414 1.41917962577125 5.70920218365142e-30 308.840018053947 25.1562790673497 12.2768560973228 1.08430006979966e-30 206.680243295246 297.295839713139 0.695200590410789 0.487231999360041 PIP5K1A other 7.80790490636168e-26 1 1.59825830288469e-26 12.2768560973228 0.695200590410789 4.93925686610635e-13 434.355773373084 56.3343581481669 7.71031724956676 6.60238366359951e-14 127.869635464001 688.331683607022 0.185767470115473 0.852700831333585 ANP32E other 4.71945993556461e-09 1 8.25496029459847e-10 7.71031724956676 0.185767470115473 0.00125606558308656 109.104140178221 30.4893926749114 3.57842943418149 0.00037743838698773 241.48315180943 375.286661861339 0.643463187878106 0.520202434324094 MINDY1 other 1 1 1 3.57842943418149 0.643463187878106 0.104672660047294 41.6012350607985 33.2644631619395 1.25062096623275 0.211625673281019 675.183484931333 409.603906383347 1.64838145928089 0.0998681556075684 ANXA9 other 1 1 1 1.25062096623275 1.64838145928089 1.25182304361368e-05 453.56520188046 100.518064594601 4.51227551694046 7.88782776818757e-06 1627.51951996851 1218.06066394015 1.33615637393941 0.18206514025955 SELENBP1 other 0.0754473748385967 1 0.0716293639629113 4.51227551694046 1.33615637393941 8.70280888829553e-11 1278.85075415626 183.94156000164 6.95248400712083 1.06374087813185e-11 -240.335840844451 2264.60749728065 -0.106126929780568 0.915521952458857 CERS2 other 7.52531884570915e-07 1 1.26149030737656e-07 6.95248400712083 -0.106126929780568 1.34763638095716e-16 687.347649478104 78.5332036668636 8.75231898591352 2.95565559269536e-17 714.297374930187 933.259641471229 0.765379046932897 0.444394444452524 ENSA other 1.46232023697662e-12 1 3.93013524160703e-13 8.75231898591352 0.765379046932897 0.0371022823164289 40.819278441667 15.8579265007989 2.57406152308819 0.0103216915905403 -22.673981637452 187.01173361259 -0.121243631078374 0.903544018460687 SEMA6C other 1 1 1 2.57406152308819 -0.121243631078374 8.44039793296157e-35 258.868545446656 19.3279209893876 13.3935018457905 1.42030466624657e-35 155.467682529443 243.64716771504 0.638085326365342 0.523685656507259 MRPL9 essential 1.20208147361239e-30 1 2.12562796350462e-31 13.3935018457905 0.638085326365342 6.97286086661731e-19 201.48783361423 21.2096574001258 9.49981557047848 7.50817759443509e-20 -314.336003214266 246.532605871612 -1.27502811282482 0.202865409016177 ARNT og 8.03343300442981e-15 1 1.03079770193999e-15 9.49981557047848 -1.27502811282482 8.75567736196568e-19 409.970955249367 43.2389649099407 9.48151640778788 7.97585130205384e-20 -423.836363874413 526.010730255828 -0.805756117690372 0.420739471744903 POGZ essential 1.00690289662605e-14 1 1.09460583269387e-15 9.48151640778788 -0.805756117690372 4.91527729789439e-19 100.088357562494 10.7869739990871 9.27863157647033 4.35401679540507e-19 233.979542864108 132.893029295755 1.76066076681407 0.078872529489547 C1orf56 other 5.68795888912339e-15 1 5.92625226022584e-15 9.27863157647033 1.76066076681407 2.42013315057552e-17 46.9996539495818 5.29170519376868 8.88175970288877 9.48993788228113e-18 79.9278215743741 66.7070702302968 1.19819115572659 0.231362443766663 OAZ3 other 2.68465370393343e-13 1 1.27117717933156e-13 8.88175970288877 1.19819115572659 6.81963931516675e-08 48.9538067325064 8.60687018268591 5.68775939376718 2.14996619783079e-08 90.8215946436194 98.4817723561938 0.922217304488909 0.356842917755202 HORMAD1 other 0.000499061205083903 1 0.000227014930828953 5.68775939376718 0.922217304488909 6.10567354371262e-07 220.85398520305 40.8641541585504 5.40458966423606 9.90994711632471e-08 -385.675286230307 467.576975363988 -0.824838062075396 0.409841740950775 GOLPH3L other 0.00415246857707895 1 0.00101220199846141 5.40458966423606 -0.824838062075396 1.71094791177404e-15 80.5918900036239 9.52872161091787 8.45778618521953 2.68346373465542e-16 62.4840663269137 117.267808319556 0.532832217317853 0.594373906059414 GABPB2 og 1.79461326465979e-11 1 3.51050725767622e-12 8.45778618521953 0.532832217317853 0.988206826680502 0.174124188742366 5.15410129462332 0.0337836178974615 0.973062347004258 -5.15566243007896 34.8797387776739 -0.147812529874193 0.882546619374819 SYT14 other 1 1 1 0.0337836178974615 -0.147812529874193 0.36813688595404 17.5987364387335 14.9902772890299 1.17401006661915 0.240914310292182 86.460820570605 97.9704575919562 0.882519309348452 0.37789313488854 KCNH1 other 1 1 1 1.17401006661915 0.882519309348452 0.00144316499103865 113.56000821269 31.4685694552112 3.60868034927099 0.00033664855875017 173.048133282368 199.192721485686 0.868747271444874 0.385374926153645 DTL essential 1 1 1 3.60868034927099 0.868747271444874 0.000169091077834086 23.3148937482113 5.78290952718951 4.03168917628603 6.33926627458884e-05 -58.3726940615791 48.2565863466912 -1.20963164783788 0.226952512531525 DYRK3 other 0.89127907126347 1 0.53376622032038 4.03168917628603 -1.20963164783788 1.90619774476403e-20 189.069758562406 19.0372575867094 9.93156486438476 1.85237906062921e-21 73.8886564200493 158.870838703178 0.465086336946312 0.642057464905274 EIF2D other 2.27676258634615e-16 1 2.58054926936256e-17 9.93156486438476 0.465086336946312 8.51676007062826e-15 179.874550142407 21.6901594366857 8.29291046326639 9.00032486729131e-16 81.8286308164631 137.907119902443 0.593360450673973 0.553190709529099 INTS7 essential 8.72627236836572e-11 1 1.16626209630361e-11 8.29291046326639 0.593360450673973 0.00620154056320648 45.3107913914699 15.0766179810886 3.00536840877083 0.00277746719611075 142.116507350032 94.4129736140978 1.50526460410957 0.132848415299832 VASH2 other 1 1 1 3.00536840877083 1.50526460410957 2.8959502723476e-13 20.7521425418165 2.65812676011093 7.80705527412485 3.08546932292091e-14 12.2165231601728 16.4439961679039 0.742916930619185 0.457856842929791 TAF1A other 2.7978997915096e-09 1 3.88861698767722e-10 7.80705527412485 0.742916930619185 2.25074760518277e-14 174.815277219953 21.4281808684239 8.15819496266982 2.44948309045186e-15 201.582872026639 129.680265558279 1.5544606664616 0.120667008454997 SMYD2 other 2.2671780627006e-10 1 3.1500352543211e-11 8.15819496266982 1.5544606664616 0.0571348474326133 94.322795457804 39.7659598488205 2.3719481641181 0.0180467867049145 161.474729546977 247.705268866094 0.651882498447249 0.514756398620421 SUSD4 other 1 1 1 2.3719481641181 0.651882498447249 0.000300188901517554 65.875803846919 20.1323734657324 3.27213301298265 0.00113598686784246 -259.881686866123 126.154105304029 -2.06003352994192 0.0398766282193867 DUSP10 other 1 1 1 3.27213301298265 -2.06003352994192 0.0413986788066551 27.747060387625 11.5714313543533 2.39789353087993 0.016830052239289 -39.2759688975577 71.5844615477286 -0.548666121786369 0.58346263530067 HHIPL2 other 1 1 1 2.39789353087993 -0.548666121786369 3.44207957882747e-05 160.933769043675 40.9200075285538 3.93288708296001 9.49988652589011e-05 681.937358108805 259.118817541584 2.63175544168793 0.00874014025688627 TP53BP2 other 0.198435887719404 1 0.786970599804737 3.93288708296001 2.63175544168793 0.294244064213819 44.6073261450261 32.0177608190465 1.39320567722183 0.164140528529452 194.615255874152 334.126289421464 0.582460171604952 0.560503996569113 ATP8B2 other 1 1 1 1.39320567722183 0.582460171604952 2.29227373698511e-10 776.566273956259 123.811942409984 6.27214353349516 7.51879485050112e-10 2911.71191462053 1320.69778535225 2.20467691164026 0.0279155783992251 ADAM15 other 1.94636963007406e-06 1 8.41052391977055e-06 6.27214353349516 2.20467691164026 3.97424160697921e-16 550.271656226696 64.98597999791 8.46754417251834 2.43430505831231e-16 877.753897343689 691.748269323789 1.26889207572825 0.205032369023075 JTB other 4.25522048859264e-12 1 3.18674875183664e-12 8.46754417251834 1.26889207572825 5.04820052997695e-09 221.919661667157 35.4092768442526 6.2672746083821 7.57732158219578e-10 4.43591389828734 377.578587662946 0.0117483195372486 0.990630800612235 RAB13 other 3.97596273740985e-05 1 8.47523418968599e-06 6.2672746083821 0.0117483195372486 0.0071735600028109 318.194220245199 236.610697507222 1.34480065186185 0.179254170858737 7219.09852696403 2599.6441556035 2.7769564197482 0.00567765558659725 S100A8 other 1 1 1 1.34480065186185 2.7769564197482 4.93842058063439e-12 1284.04628605328 174.265699364968 7.3683248667546 6.68464687809964e-13 -78.8503224498341 1816.22554189871 -0.0434143891443145 0.965387589512236 TPM3 other 4.54334693418364e-08 1 8.15259533253032e-09 7.3683248667546 -0.0434143891443145 4.58771588181397e-35 142.206352251524 10.5280444693768 13.5073852190844 5.11464208563027e-36 67.212417389286 104.36123253257 0.644036255209132 0.519825878767313 SNAPIN other 6.54804687811308e-31 1 7.66122238006558e-32 13.5073852190844 0.644036255209132 0.000484546008854425 65.6040576291443 18.7430460501764 3.5001812113953 0.000503508451123004 311.642873523488 192.199970673589 1.62145120226239 0.105506782418459 SLC27A3 other 1 1 1 3.5001812113953 1.62145120226239 0.113639474917271 384.890867267686 206.819820432525 1.86099604217216 0.0632889843792319 1916.51327101682 2203.93239545265 0.869588048604006 0.384912641929436 S100A7 other 1 1 1 1.86099604217216 0.869588048604006 2.28578565041984e-23 741.282816883351 69.0521792169 10.7351111187223 1.88160454377106e-24 -595.886538867607 719.162890466366 -0.828583547297864 0.407714488329088 UBAP2L other 2.880089919529e-19 1 2.68542600487005e-20 10.7351111187223 -0.828583547297864 2.07626347094567e-19 502.611965632332 53.7850224936078 9.34483137367964 2.47762869967042e-19 1002.39885006691 555.004851619016 1.80610826579766 0.0714632882757936 SLC39A1 other 2.42881300831224e-15 1 3.38295422652999e-15 9.34483137367964 1.80610826579766 9.62872953268242e-31 320.279355075599 25.6617313113734 12.4808163248771 1.60098205725748e-31 82.2314629712322 267.701107415395 0.307176401940066 0.758829762988678 HAX1 other 1.32587605665037e-26 1 2.366571677038e-27 12.4808163248771 0.307176401940066 5.61655588806275e-11 624.62799225308 90.3377652773659 6.91436178806585 1.34660610438317e-11 594.318741079207 961.607300331646 0.618047243270963 0.536807693704053 CREB3L4 other 4.90774653498924e-07 1 1.59182307599135e-07 6.91436178806585 0.618047243270963 4.38608464806286e-07 118.064830982542 22.6516911990715 5.21218614296587 2.68742151582925e-07 338.691341791409 236.083247167641 1.43462675075333 0.151988885165572 EFNA3 other 0.00302069649712089 1 0.0026788217669786 5.21218614296587 1.43462675075333 0.0695871497218762 -4.64548226608904 2.90485849241545 -1.59921121053516 0.110368485531495 -47.4550633927139 31.141312231247 -1.52386203382585 0.128138497845508 KCNN3 other 1 1 1 -1.59921121053516 -1.52386203382585 1.65451407956198e-21 942.161405313393 92.998381278696 10.1309441342849 3.63918375656724e-22 531.305342675882 969.244297926117 0.5481645275734 0.583810173865415 C1orf43 other 2.01734901720992e-17 1 5.09958819807768e-18 10.1309441342849 0.5481645275734 1.02886101931834e-22 247.024624822319 23.5649250555603 10.4827248225868 1.58933531548552e-23 -422.472682878766 241.686135021038 -1.74802200731123 0.0810295878787267 GATAD2B other 1.28401855210928e-18 1 2.25399534442156e-19 10.4827248225868 -1.74802200731123 9.58831877902766e-19 1017.70340290204 107.491456319188 9.46776085980304 8.92917759989244e-20 -679.621148938497 1065.5398415529 -0.637818617789109 0.523863121092841 ILF2 essential 1.10188959408586e-14 1 1.22472599960125e-15 9.46776085980304 -0.637818617789109 1.03092933090321e-14 108.094815074627 13.0976232946963 8.25300992725893 1.22850571434814e-15 32.6538169271157 125.270034994116 0.260667420813362 0.794450047544634 RIT1 other 1.05185719632054e-10 1 1.58772078522354e-11 8.25300992725893 0.260667420813362 4.7237269618843e-16 384.818438001386 45.6012316576434 8.43877290180352 2.97936530874681e-16 761.820263884974 467.533522813963 1.6294452198845 0.103804134595173 INTS3 essential 5.04257853181149e-12 1 3.89522220465557e-12 8.43877290180352 1.6294452198845 1.42401247185707e-13 59.5480716720181 7.61864439903214 7.81609805539461 2.9616773738379e-14 63.5665208179812 79.1274268832054 0.803343711805609 0.422136906613927 HCN3 other 1.39299356401807e-09 1 3.73349049746006e-10 7.81609805539461 0.803343711805609 0.238573800088147 3.15200998232296 1.87575336721427 1.68039681411 0.0934573915297311 -9.21620392616147 29.3368889345685 -0.314150690849218 0.753527694795713 FLG other 1 1 1 1.68039681411 -0.314150690849218 0.679057258003055 1325.22694420963 1584.34981316335 0.836448449199266 0.403271965953398 -1995.22969146238 9461.98681321513 -0.210867942520881 0.833069721184418 ACTA1 other 1 1 1 0.836448449199266 -0.210867942520881 6.59215062444542e-32 69.5810828661169 5.43059296154255 12.8127965691527 5.03116911612213e-33 35.0659155450083 33.1189546565894 1.05878690642887 0.290167598481705 C1orf131 other 9.17956974454025e-28 1 7.47279548817619e-29 12.8127965691527 1.05878690642887 1.55578505443073e-12 320.373318567034 46.4342300839331 6.89950749668804 1.45313504682145e-11 -727.428195070577 275.250096541793 -2.64278997250098 0.0084590914702079 GALNT2 other 1.45917080255058e-08 1 1.71600717679145e-07 6.89950749668804 -2.64278997250098 4.45742614033561e-15 90.4909736411773 10.9431955988604 8.26915436388629 1.04057957973111e-15 121.990939637771 65.8979643920603 1.85120952920465 0.0646811943780987 TTC13 other 4.61254457001928e-11 1 1.34650997617206e-11 8.26915436388629 1.85120952920465 3.92430243840337e-08 378.534522352164 67.2784573722807 5.62638528195689 2.96325715163684e-08 -699.656880364596 423.140533662724 -1.65348583910961 0.0988153642202287 SCCPDH other 0.000292595989807355 1 0.000311023470635803 5.62638528195689 -1.65348583910961 7.07116373482029e-05 101.031109505831 28.9114765333537 3.49449843522437 0.000513589391696684 -442.251390280651 180.751331577425 -2.44673932092839 0.0147303339785287 LYST other 0.391883894183741 1 1 3.49449843522437 -2.44673932092839 1.11547059269906e-06 51.2325605666218 10.0733323224743 5.0859595341969 5.04196416381782e-07 107.606319298763 60.8581043467321 1.76815102037501 0.0775960927936596 MAP3K21 other 0.00741007114729989 1 0.00494465425545614 5.0859595341969 1.76815102037501 7.22082521477542e-26 430.855942925572 40.7891828899475 10.5629951962523 7.45297759214597e-24 -221.993039480233 126.461773841849 -1.75541614462765 0.0797499353076621 ACP1 other 9.44844979353364e-22 1 1.05988794337908e-19 10.5629951962523 -1.75541614462765 5.35307769815721e-24 264.822275278864 24.3330909097302 10.8832156285155 4.55823390370524e-25 74.7551328279394 152.580866420801 0.489937792211595 0.62437764146963 SNAP47 other 6.81125606313523e-20 1 6.53286083079035e-21 10.8832156285155 0.489937792211595 1.06019169863784e-14 710.011212031567 88.1734891037927 8.05243411878352 5.1794673106882e-15 -796.272563866242 563.137320142523 -1.41399359514073 0.15793791349364 SRP9 essential 1.08118349427087e-10 1 6.62246690344593e-11 8.05243411878352 -1.41399359514073 5.11204734370269e-09 179.398622681378 28.7839727132971 6.23258729669733 9.30758772899671e-10 -76.7784798579296 179.983333292495 -0.426586609178723 0.669852049283612 NVL essential 4.0252260784315e-05 1 1.03751680415126e-05 6.23258729669733 -0.426586609178723 6.91457155255469e-15 116.010607985264 13.9883998916414 8.29334369076656 8.78054665934662e-16 -19.1680806871117 87.859205878446 -0.218168153188534 0.827380365082582 SDE2 essential 7.1116368418025e-11 1 1.1383100689177e-11 8.29334369076656 -0.218168153188534 0.00010277248916874 573.335194603701 133.254913333496 4.30254450107082 2.0078137063644e-05 -99.5404432201917 833.229787918942 -0.119463375725923 0.904953099089493 DEGS1 other 0.557643526229584 1 0.176406512241176 4.30254450107082 -0.119463375725923 9.19714693113722e-19 270.993888912689 28.9620028987528 9.35687665870511 2.24658511391256e-19 -157.875908700616 181.096538426622 -0.871777616912238 0.38372075510868 FBXO28 other 1.05730401120354e-14 1 3.0701832166729e-15 9.35687665870511 -0.871777616912238 0.000474688163196724 0.389179339261373 8.44863777643737 0.0460641525367279 0.963276147544194 208.837120657212 53.0662929134765 3.93540059407799 9.3910620217394e-05 LEFTY2 other 1 1 1 0.0460641525367279 3.93540059407799 3.37593801827964e-15 232.153852223476 27.5674090609122 8.42131560896837 3.43803487878328e-16 139.794704141997 172.376281149288 0.81098572964877 0.417734489984574 CNIH4 other 3.50793719479437e-11 1 4.49041735517884e-12 8.42131560896837 0.81098572964877 0.00172238313760849 196.389419226183 56.3205960930111 3.48699113379151 0.000528271277425046 -209.847025701991 357.934933796682 -0.586271430609204 0.557938100546441 ITPKB other 1 1 1 3.48699113379151 -0.586271430609204 5.80362845716006e-09 541.027465979736 88.0891529911199 6.14181709789258 1.6325797685406e-09 -387.483771412458 538.524624948335 -0.719528417943066 0.472141782228985 GUK1 essential 4.55642870171637e-05 1 1.80024571076972e-05 6.14181709789258 -0.719528417943066 1.09592071419296e-06 241.360014838264 45.6319303189277 5.28927908925541 1.78708022757996e-07 2.80174237292764 294.219999722913 0.00952261020857262 0.992405688074628 CDC42BPA other 0.00728458498724058 1 0.00179833883301371 5.28927908925541 0.00952261020857262 0.000440906819571636 10.3065741243437 3.67842637345053 2.8018976263145 0.00526399727919718 -59.1613881685659 23.0431512813182 -2.5674174268226 0.0105159949651592 CNIH3 other 1 1 1 2.8018976263145 -2.5674174268226 7.42973263334308e-13 103.058577571758 13.4250725524708 7.67657509253394 8.09956775889545e-14 71.1347093109177 82.5909671907944 0.861289215158221 0.389474224175815 C1orf35 other 7.05007329577925e-09 1 1.01074506063256e-09 7.67657509253394 0.861289215158221 1.61881245127958e-05 426.581070963091 118.862559756447 3.58885987174741 0.000362298091894669 -824.112794986267 365.828722021205 -2.25272851850735 0.024676171020485 MBOAT2 other 0.0966431033413911 1 1 3.58885987174741 -2.25272851850735 4.54322176227018e-21 1092.33894174712 108.068977975181 10.1077937648117 4.0616643997555e-22 284.731433546321 686.888244409319 0.414523666497121 0.678654950125603 PARP1 other 5.49775265452314e-17 1 5.68998565761747e-18 10.1077937648117 0.414523666497121 2.98392879898953e-23 130.975329667621 12.4041923467013 10.5589566822907 8.05410025285629e-24 -71.2081072597386 78.8325066568107 -0.903283560038701 0.366778178875183 PSEN2 other 3.75288725048913e-19 1 1.14513197395111e-19 10.5589566822907 -0.903283560038701 3.14664491842285e-05 125.12864273831 31.015922091842 4.03433573142814 6.26570369462344e-05 499.990509919329 200.685309862501 2.4914155912154 0.0130225683573642 LBR other 0.182190740776683 1 0.527822879235079 4.03433573142814 2.4914155912154 0.00476330652936873 21.038860653004 8.23610943977571 2.55446589276708 0.0109114282812787 -95.6196457177824 51.4037525389199 -1.86016858682418 0.0634112453123155 WNT9A other 1 1 1 2.55446589276708 -1.86016858682418 1.11785474543513e-06 527.713035844882 108.083394392798 4.88246172142837 1.380502128185e-06 -1236.05698525941 690.295843897252 -1.7906191905791 0.0739123872689009 EPHX1 other 0.00742479121918011 1 0.0131699903028849 4.88246172142837 -1.7906191905791 7.37574368373489e-21 304.118843280054 30.502735201063 9.97021549954167 1.32503664292499e-21 -426.64443897979 257.147902485237 -1.65914026463538 0.0976681648553796 SOX13 other 8.89293415947915e-17 1 1.84855862054465e-17 9.97021549954167 -1.65914026463538 5.71396786535685e-06 202.090571266434 41.5558512448922 4.8631074857665 1.51786184688031e-06 -415.766796557268 350.329238121575 -1.18678874417266 0.235832802045053 ETNK2 other 0.0354665985402699 1 0.0144394197493724 4.8631074857665 -1.18678874417266 0.00355084674162966 10.2847589831563 4.89620017009901 2.10055933700692 0.036140200020224 99.5065284212211 38.4121202481417 2.5904982015679 0.00984118623582582 PPFIA4 other 1 1 1 2.10055933700692 2.5904982015679 1.13292544743013e-18 426.322466303714 46.5377260031971 9.16079282160082 1.06573294790683e-18 -1109.60677169923 397.731542709765 -2.78983850297471 0.00545973400789243 PLEKHA6 other 1.29923890311287e-14 1 1.44492073077207e-14 9.16079282160082 -2.78983850297471 0.0385075042569263 -0.177907524375966 5.67842638495022 -0.0313304271844542 0.975017515995625 107.429107531968 41.9728424264072 2.5594908831902 0.0107517942262459 PTPN7 other 1 1 1 -0.0313304271844542 2.5594908831902 0.71621217790546 1.67809290042448 2.19051881190683 0.76607098341407 0.44396694925475 -4.88297601267854 16.8783474855043 -0.28930415236872 0.772459058458704 SYT2 other 1 1 1 0.76607098341407 -0.28930415236872 2.67996851516202e-25 263.31974689841 23.6347605712279 11.1412064490708 4.14340632697838e-26 -215.230103630248 174.699470239008 -1.23200203947836 0.218480567766023 ARL8A other 3.47618716101666e-21 1 5.97230587970664e-22 11.1412064490708 -1.23200203947836 0.0292126263592383 60.7981804375635 24.6599007627901 2.46546736024596 0.013991621747136 112.698651282583 70.9106671979661 1.58930462419645 0.112573675257822 OSR1 other 1 1 1 2.46546736024596 1.58930462419645 0.491827445094927 1.94922381511379 1.65684810357132 1.17646500660638 0.239925543895101 0.481887975304415 4.79293274614519 0.100541359711751 0.919951727845239 GDF7 other 1 1 1 1.17646500660638 0.100541359711751 5.04137915119573e-28 2861.25663049735 240.766700493292 11.8839383711913 4.1218761318246e-29 1921.51209694537 709.739072481487 2.70735002685862 0.00699590263881583 PDIA6 other 6.76704323465003e-24 1 6.03442665699122e-25 11.8839383711913 2.70735002685862 3.25682496487322e-07 -691.190070372514 496.853577050663 -1.39113433473789 0.164754419591839 -7967.73965394795 1437.83792409292 -5.54147273516556 4.68326122159088e-08 RHOB other 0.00226642449305527 0.00062662035144886 1 -1.39113433473789 -5.54147273516556 1.27939948609755e-25 1330.21821924582 117.873957290786 11.2850900217448 1.1177531539976e-26 865.78881998878 347.472274803283 2.49167741650448 0.013011426461833 ATP6V1C2 other 1.66769723012815e-21 1 1.61660638662673e-22 11.2850900217448 2.49167741650448 2.24240386466632e-05 86.8844460193509 18.5925933754887 4.67306761701645 3.75148090828481e-06 56.2600710047917 58.2646232204727 0.965595723358653 0.334678745296009 HNRNPLL other 0.131629106855913 1 0.0348212457906996 4.67306761701645 0.965595723358653 0.187241886760364 28.9397356380289 20.3685418688442 1.4208054668015 0.155949417446169 -55.0371668000719 63.9727833045982 -0.860321592356228 0.389992885392127 GALM other 1 1 1 1.4208054668015 -0.860321592356228 6.49862276890923e-11 27.2858166137799 3.96521466560822 6.88129620079336 1.64052317010161e-11 -2.35130855425111 13.1755906876652 -0.178459441401164 0.858428731530295 CAMKMT other 5.66030043171994e-07 1 1.93466897450082e-07 6.88129620079336 -0.178459441401164 7.83926741709422e-16 451.121486496758 52.4061824604659 8.60817303067389 8.04361980594058e-17 197.41656730234 167.767474150278 1.17672730248954 0.239819941353838 EML4 other 8.31667880279526e-12 1 1.06248174016669e-12 8.60817303067389 1.17672730248954 2.12438357969893e-13 2084.31701497826 276.347663273248 7.5423724966233 1.94854787815753e-13 -1038.45725553436 962.000025017592 -1.07947736853268 0.280853346053851 CALM2 other 2.06362620931954e-09 1 2.41093828964431e-09 7.5423724966233 -1.07947736853268 1.28532027106579e-17 26.7719781042848 2.93135869769987 9.13295876253281 1.31866271745491e-18 9.56956231581892 10.4434656223629 0.916320564633956 0.359906303717957 CHAC2 other 1.43608833886181e-13 1 1.7856011857057e-14 9.13295876253281 0.916320564633956 0.000251789932394451 510.732062659166 134.651902981113 3.79298065123375 0.000165564961118459 -469.896181987953 472.488071401963 -0.99451438127037 0.320415471270759 RPS27A essential 1 1 1 3.79298065123375 -0.99451438127037 2.41331007814176e-07 18.0072173341098 3.80904006618655 4.72749485991567 2.89900847924705e-06 -29.094517014978 13.4194290659439 -2.16808903508531 0.030584737019279 WDPCP other 0.00169631565392584 1 0.0271173253148769 4.72749485991567 -2.16808903508531 8.44942572598417e-11 178.52878422161 26.4833633289941 6.74116735113309 4.03146409519496e-11 -54.5642438300204 93.1268538324513 -0.585913102231386 0.558177808162094 VPS54 other 7.3129779658393e-07 1 4.69504308526405e-07 6.74116735113309 -0.585913102231386 9.2584305964507e-08 122.955541829457 36.2072165089451 3.39588495567123 0.000734313810510381 -405.172045928523 110.014428106883 -3.68289916968785 0.000253759167835999 ASXL2 other 0.000670402959488995 1 1 3.39588495567123 -3.68289916968785 0.006478965773666 -0.254624876969789 10.7012333007287 -0.0237939749386129 0.981025639151257 -110.406449427975 35.1325473675085 -3.14256886279991 0.00176560184555002 ETAA1 other 1 1 1 -0.0237939749386129 -3.14256886279991 7.11751262849849e-16 102.917023813333 12.2463751948522 8.40387642676461 3.79083755547223e-16 -21.6546127919138 40.7783078334392 -0.531032648053055 0.595612889313589 SNRPG essential 7.5602219139911e-12 1 4.94666392613572e-12 8.40387642676461 -0.531032648053055 1.23771339661464e-05 4.9444616664763 2.14945956300316 2.30032783662515 0.0218106854082105 -23.4581749359612 6.59978964420495 -3.55438221528151 0.000412149920769288 ABHD1 other 0.0746341178158625 1 1 2.30032783662515 -3.55438221528151 0.658721671346247 -12.4538019220148 13.8612506723756 -0.898461633540346 0.369335521296949 0.221821833428884 45.9000621948316 0.00483271313418528 0.99614583297181 MEIS1 other 1 1 1 -0.898461633540346 0.00483271313418528 9.38980999075857e-21 207.380508974284 26.8844816817414 7.71376258725221 6.36763219063929e-14 -502.447449773297 100.613001454556 -4.99386205072352 8.11605238641038e-07 CIAO1 essential 1.12931244758853e-16 0.0103520248188664 7.96590787048976e-10 7.71376258725221 -4.99386205072352 0.000838880683704606 20.5863952907861 13.1723350726466 1.56285086715835 0.118738568544651 -153.492714952845 49.6562779775995 -3.09110390879654 0.0021086194564271 ZNF514 other 1 1 1 1.56285086715835 -3.09110390879654 6.35265731383781e-11 1008.55737456771 176.545504789029 5.71273324558975 1.88220235486797e-08 -1984.8551569304 660.70729353869 -3.00413689441764 0.00279297512580221 SNRNP200 essential 5.53507031754688e-07 1 0.000199268763309872 5.71273324558975 -3.00413689441764 2.3895592786908e-22 206.07928202942 20.0127505443502 10.2973992291928 1.25835148219733e-22 -7.73598565756551 75.4428655698436 -0.102540983817796 0.918369578778389 MRPS5 essential 2.96257559372085e-18 1 1.77062637059987e-18 10.2973992291928 -0.102540983817796 0.639204193939194 1.13713578672839 1.48819089729217 0.764106129662165 0.445137740989396 -2.11096123979977 4.97006641373593 -0.424735016410574 0.671199032089089 ANKRD53 other 1 1 1 0.764106129662165 -0.424735016410574 1.57356432807841e-13 83.342115238817 11.4438776955316 7.28268140014804 1.15178319032707e-12 -72.3657261995022 38.9379096410065 -1.85849026993714 0.0636383329309214 TPRKB other 1.53674292280138e-09 1 1.39791925809996e-08 7.28268140014804 -1.85849026993714 0.00467588406347475 62.6852316046649 24.3770131931184 2.57148942358372 0.01039019450639 -134.67025472099 82.7565670169702 -1.62730595982038 0.104250097570095 EXOC6B other 1 1 1 2.57148942358372 -1.62730595982038 0.0058500875905853 -116.165168417633 51.472230033744 -2.25685128352663 0.0244118652931199 -455.39220541082 173.290950554245 -2.62790528850073 0.00883291312291273 SFXN5 other 1 1 1 -2.25685128352663 -2.62790528850073 8.52680915737361e-07 289.64120851375 55.5382501196645 5.21516626630619 2.62078276356007e-07 -63.4671347300019 185.479424783242 -0.342178841691858 0.732349441642129 TEX261 other 0.00573342647741802 1 0.00261423080665117 5.21516626630619 -0.342178841691858 0.0108775200784372 19.7624776563473 7.2424363687942 2.72870573519966 0.00656595102407036 -21.7179631746077 24.7740932007619 -0.876640085213686 0.381072691979161 DQX1 other 1 1 1 2.72870573519966 -0.876640085213686 6.08141436588534e-09 51.3138651214845 10.2986984737786 4.9825582574472 8.43931293195971e-07 -103.738790209033 35.0414257527885 -2.960461453278 0.00320550135784678 DUSP11 other 4.76782886285411e-05 1 0.00815912774261865 4.9825582574472 -2.960461453278 0.00199653927242069 -42.5332786117713 16.5377259155691 -2.57189403361252 0.0103777227081676 -150.504908938975 52.4470702309649 -2.86965331478357 0.00426839925508414 ST6GAL2 other 1 1 1 -2.57189403361252 -2.86965331478357 3.76322772523786e-06 8.06231612756454 5.93472477734341 1.3584987392075 0.174872706701825 -77.0240266408588 17.2316691486678 -4.46991095153504 9.54072896244824e-06 NPHP1 other 0.0238061785898547 0.115328331698074 1 1.3584987392075 -4.46991095153504 0.00232058737161483 123.199436443331 35.5074964469136 3.46967397793092 0.000562489797991111 125.411500730536 103.880651047172 1.2072652555247 0.227855623829723 MALL other 1 1 1 3.46967397793092 1.2072652555247 0.154941738009124 5.71649285102823 44.3092708460783 0.129013471489662 0.897396587074142 -321.201421664243 170.697684897043 -1.88169758633795 0.0604321909198048 THNSL2 other 1 1 1 0.129013471489662 -1.88169758633795 5.08711113141247e-11 134.355928914784 45.9032633910164 2.92693632194086 0.00356767099960441 -596.843945755467 110.100016170211 -5.4209251416709 8.9585578308323e-08 RALB other 4.45274837332533e-07 0.00118763601163344 1 2.92693632194086 -5.4209251416709 0.662026727984542 5.89594384653339 6.89270001741047 0.855389590674287 0.39271208099686 8.72763657828224 16.8016667043939 0.519450643310276 0.603657800115125 C1QL2 other 1 1 1 0.855389590674287 0.519450643310276 1.25038734681686e-06 25.5992182026534 7.81908331043784 3.27394109850198 0.00112837162639387 -59.0579423441429 18.7736148897611 -3.14579491967486 0.0017474362958063 TMEM177 other 0.00827506346123398 1 1 3.27394109850198 -3.14579491967486 9.90995000161394e-09 6.77748459111737 1.38565680433806 4.89117115428524 1.32129638594309e-06 17.2465496396412 3.65282964366736 4.72142183513549 2.98212632807282e-06 NT5DC4 other 7.66534632624838e-05 0.0370439732473206 0.01263027215323 4.89117115428524 4.72142183513549 0.00282204014255625 -6.75420197358819 13.0567762679598 -0.51729476211999 0.605160674632253 -119.755611716713 34.8583513864249 -3.43549269984553 0.000636633288389991 RABL2A other 1 1 1 -0.51729476211999 -3.43549269984553 3.22997648561059e-05 156.307952160599 64.6612731971708 2.41733489663853 0.0159617970348425 -564.283103791523 170.941218131711 -3.30103593480153 0.00102632923129122 SLC20A1 other 0.186757240398004 1 1 2.41733489663853 -3.30103593480153 0.0561646491568463 1.78103886593486 14.6226343039224 0.121800137302012 0.903102283403304 -88.0908341220344 38.152238275599 -2.30892964878484 0.021321345434876 FBLN7 other 1 1 1 0.121800137302012 -2.30892964878484 4.74804947186685e-06 29.8546263990183 8.15785803944656 3.65961582742173 0.000277205968581949 -54.4103548136342 21.4615268959668 -2.53525087368594 0.011515636695315 ZC3H8 essential 0.0297085455454709 1 1 3.65961582742173 -2.53525087368594 1.32145570642102e-08 10.7952203570219 3.14025784049699 3.43768598164327 0.000631609020786414 -44.8527374582748 10.202285942593 -4.39634192872613 1.32442665484324e-05 LIPT1 other 0.000101355652682492 0.158798755915705 1 3.43768598164327 -4.39634192872613 0.56749497812478 -14.0026063604872 16.5743001252133 -0.84483847008333 0.39857242885956 -45.2608197917795 57.2107317312091 -0.791124644313704 0.429216037544322 CNGA3 other 1 1 1 -0.84483847008333 -0.791124644313704 0.000752023061948792 36.4584746315168 10.2969942114104 3.54069099030046 0.000433817887628273 -30.3200395869256 44.2872051610115 -0.684623007405714 0.49387776353066 FAHD2B other 1 1 1 3.54069099030046 -0.684623007405714 2.20038586740042e-05 4.91819221840048 1.051485788805 4.6773739319767 3.67193297624553e-06 2.72308519787772 3.33744417928882 0.815919323767682 0.414904045449088 LYG1 other 0.129338681285797 1 0.0341049134833685 4.6773739319767 0.815919323767682 6.85936651253615e-05 -1042.09482211811 296.268456054722 -3.51740052246949 0.000472355288408429 -3059.2675894735 935.495775976102 -3.27020994432759 0.00114293759026745 AFF3 og 0.381106403436509 1 1 -3.51740052246949 -3.27020994432759 7.75290560310576e-15 364.851758338699 108.175350650564 3.37278091676606 0.000797279630150997 -1496.94664659675 248.532156935723 -6.02315074658086 3.15848886759586e-09 UBXN4 other 7.95758231102776e-11 4.37387538384675e-05 1 3.37278091676606 -6.02315074658086 1.5406865301162e-06 -46.9782825470389 90.1508145542313 -0.521107688037345 0.602506975396021 -1079.98058185645 211.754627327929 -5.10015103558502 4.71629057326432e-07 SPOPL other 0.0101099850106225 0.00607438259584633 1 -0.521107688037345 -5.10015103558502 0.000844490944986535 -12.5099835794903 4.05525803214847 -3.08487979810808 0.0021408041064745 -29.0840043648931 9.45201319513333 -3.0770169025862 0.00219707252663855 THSD7B other 1 1 1 -3.08487979810808 -3.0770169025862 8.64258031375989e-18 204.501646332912 23.2129693870552 8.80980123322581 1.6894348636274e-17 1.05185808442012 60.0558027319689 0.0175146786250547 0.986032456315084 POLR2D essential 9.7073462084151e-14 1 2.2543818820244e-13 8.80980123322581 0.0175146786250547 1.41569919668373e-16 112.762901568304 20.4961128432242 5.5016725576617 5.79919125679286e-08 -264.044108161844 52.8200317110612 -4.99893884210882 7.78610623143774e-07 AMMECR1L other 1.53560891864284e-12 0.00993896460443027 0.000600274286990628 5.5016725576617 -4.99893884210882 0.000810879565069452 71.6594241590731 19.0079184687396 3.76997745844312 0.000181266064087762 33.9644893215945 47.5232464553492 0.714692110807416 0.475108156407011 GALNT13 other 1 1 1 3.76997745844312 0.714692110807416 4.3187874925657e-07 8.89796558412365 93.9456745514225 0.0947139464015793 0.924576852046243 -1208.60327175096 233.774862049866 -5.16994539598169 3.29301864026302e-07 PKP4 other 0.00297650833987628 0.00426445913914062 1 0.0947139464015793 -5.16994539598169 0.942073610449674 2.93902486327141 14.7007458600218 0.199923520293211 0.84161538167025 12.0083898995385 36.5861336457479 0.328222435740601 0.742870244871933 SCN1A other 1 1 1 0.199923520293211 0.328222435740601 0.0680718944991346 2.92092509287874 32.8925068456736 0.0888021428887515 0.929271776267036 182.130270364116 81.3715680096385 2.23825440284674 0.0256075057682605 SLC4A10 other 1 1 1 0.0888021428887515 2.23825440284674 1.50211179614268e-11 43.0695276132855 14.3406055983894 3.00332697373133 0.0027937441110315 -188.600137084156 34.9722898165385 -5.39284496592974 1.03716997220421e-07 SCRN3 other 1.34889639293613e-07 0.00137227959022339 1 3.00332697373133 -5.39284496592974 1.35864476340585e-08 165.440257587518 36.8954898973167 4.48402387522031 8.94220097743334e-06 -243.286851171435 89.5687644239959 -2.71620193418966 0.00681404188371789 LNPK other 0.000104126534667424 1 0.0809179766447943 4.48402387522031 -2.71620193418966 0.311558986072846 -10.5646021987387 43.3435786619339 -0.243740884460401 0.807523735893918 -175.210422555075 115.30428359697 -1.51954825171541 0.129207655833298 ZNF385B other 1 1 1 -0.243740884460401 -1.51954825171541 3.68698154942235e-09 142.62043972719 28.3989331901172 5.02203511562969 6.94224463571356e-07 362.194766185875 69.6234847995249 5.20219243878392 2.79413698188288e-07 CDCA7 other 2.92856944470618e-05 0.00362818687097492 0.00674647333698643 5.02203511562969 5.20219243878392 0.481121874048334 21.3785085625025 17.8241111121583 1.19941513088525 0.230890634583164 22.2783274336019 43.8325983316575 0.508259338518649 0.611478276604215 DLX1 other 1 1 1 1.19941513088525 0.508259338518649 1.96559529450539e-07 181.302854926807 50.0147806951047 3.62498550242673 0.000316164905903427 -405.439965814966 128.548011514258 -3.15399640211469 0.00169959973248454 UBR3 other 0.00139144490898037 1 1 3.62498550242673 -3.15399640211469 3.08207923248713e-06 4.34596709396997 5.57987992614537 0.778863909527208 0.436399170774487 -66.1204105922097 14.3565675493377 -4.60558628411565 5.12894167493182e-06 PHOSPHO2 other 0.0196698296617329 0.0630039195348624 1 0.778863909527208 -4.60558628411565 0.0647751104758566 30.6881471545492 18.9898639393406 1.61602775315171 0.106681132089506 -61.0008628658095 49.6515564154538 -1.22857906719765 0.219772867766406 GULP1 other 1 1 1 1.61602775315171 -1.22857906719765 0.959800534247922 -13.2879829480397 46.9470473166439 -0.283041931442806 0.777255000304225 -13.7263937927029 120.267759426407 -0.114131949062393 0.909176336132781 FAM171B other 1 1 1 -0.283041931442806 -0.114131949062393 2.93035921794248e-12 1850.64846527185 251.604456456736 7.35538826034298 7.16310740925413e-13 1867.88037971988 645.669854254255 2.8929341635088 0.0039714915282905 HSPD1 essential 2.7208385338596e-08 1 8.73111162113986e-09 7.35538826034298 2.8929341635088 8.66973232206163e-08 13.2914059878625 3.04586383160254 4.3637558087649 1.53271000996499e-05 36.6504187428501 7.7035439244037 4.75760495461666 2.51899575677842e-06 CCDC150 other 0.000629595961228115 0.0314194340742973 0.13595824860144 4.3637558087649 4.75760495461666 2.12486296743116e-14 60.4388309940648 8.14764584438188 7.4179501844376 4.59751829403073e-13 -26.7179867392548 20.0397160270547 -1.33325176380664 0.183007229131838 METTL21A other 2.14313678895107e-10 1 5.6309659154687e-09 7.4179501844376 -1.33325176380664 0.93177274362507 2.02857967120581 6.10683563275409 0.332181803015215 0.739879700050662 -1.12613570694019 14.5625479015494 -0.0773309529728907 0.938388648701971 UNC80 other 1 1 1 0.332181803015215 -0.0773309529728907 0.00020938521231551 41.5324484914555 10.2003582543132 4.07166566663418 5.3585596101831e-05 46.1374986939173 24.3982722177617 1.89101499819851 0.0591514567602656 PTH2R other 1 1 0.454137926963018 4.07166566663418 1.89101499819851 0.00200170905728435 -541.876145167388 241.53013697599 -2.24351359193431 0.0252690167152025 -1952.08108385562 596.435191173562 -3.27291399425082 0.0011326558916888 NBEAL1 other 1 1 1 -2.24351359193431 -3.27291399425082 3.49713161672951e-07 70.6908471172927 13.2160545877246 5.34886161736589 1.30653707634457e-07 4.84600088122559 30.693513596337 0.157883549760948 0.874607255079541 KANSL1L other 0.00243015676046534 1 0.00132508990282866 5.34886161736589 0.157883549760948 0.0455624353865215 7.05488751830494 34.5092273414852 0.204434815317465 0.838090610715978 -185.698622831125 79.8937969528624 -2.3243184066053 0.0204777833554868 SPAG16 other 1 1 1 0.204434815317465 -2.3243184066053 0.0109377865250796 223.904337004861 99.459648013706 2.25120781619905 0.0247707080528926 -290.444926371153 227.100228039491 -1.27892837835745 0.201467566312577 ABCA12 other 1 1 1 2.25120781619905 -1.27892837835745 4.31803865403766e-19 221.696747198367 40.6523076745255 5.45348492817032 7.5864956205141e-08 -717.227328854281 105.411071419786 -6.80409865106122 2.75630095319452e-11 SUMF1 other 5.00633401549127e-15 3.97651538517374e-07 0.000780650399350901 5.45348492817032 -6.80409865106122 1.18200344967513e-16 29.9451914696613 19.2678356036562 1.55415439936486 0.120728074403294 -329.353163349044 41.4019193644968 -7.95502161263258 1.04168773842239e-14 RHBDD1 other 1.28590155290158e-12 1.56013572583522e-10 1 1.55415439936486 -7.95502161263258 0.00366169434747563 221.579842622485 71.7544634681138 3.08802870111279 0.00211710573150041 -31.2221910720181 139.92069819977 -0.223142047414894 0.823508257436199 ACKR3 other 1 1 1 3.08802870111279 -0.223142047414894 0.563888729735498 -0.87645349398917 20.7382497933871 -0.0422626548875232 0.96630473762543 40.2084982996561 40.2310614333055 0.999439161363247 0.318023906467672 TRPM8 other 1 1 1 -0.0422626548875232 0.999439161363247 0.00457616016402443 84.9033021807645 25.7593725939824 3.29601592084578 0.00104423877988351 65.1444270055632 49.9649442667233 1.30380265527384 0.192849299627048 HES6 other 1 1 1 3.29601592084578 1.30380265527384 0.0264242120192378 -0.142723322963227 3.24675361606124 -0.0439587784725007 0.964953304061334 -15.9964709583272 6.29766361282334 -2.54006437018248 0.0113586941634074 ESPNL other 1 1 1 -0.0439587784725007 -2.54006437018248 2.84188525530489e-17 12.710258305121 15.1705536698983 0.837824286554608 0.402495991780876 -239.98023510367 29.5203326867726 -8.12932014181533 2.91073000782481e-15 ANKMY1 other 3.14710373172464e-13 4.38093973477712e-11 1 0.837824286554608 -8.12932014181533 1.21716889131864e-07 104.576415450049 22.0468274567384 4.74337705301386 2.68780085576655e-06 -70.8506370277515 44.3952667281555 -1.5959052000203 0.111089625497395 COPS7B other 0.000875387866636368 1 0.0251785769808586 4.74337705301386 -1.5959052000203 6.70752898317997e-24 71.646009949959 12.9069923952327 5.55094539115263 4.44933083929214e-08 -184.700565604426 25.8396882974783 -7.1479409301718 2.85533316788477e-12 DIS3L2 other 8.52057406733352e-20 4.17621029134826e-08 0.000463130847061919 5.55094539115263 -7.1479409301718 5.13271940776941e-44 298.126736192254 19.4366199897922 15.3384043289844 2.10805180390082e-44 257.655672211938 59.3675329407181 4.34000975700341 1.69853196397069e-05 FANCD2 other 7.63851302264244e-40 0.202329127548189 3.2071900144547e-40 15.3384043289844 4.34000975700341 4.54750172724254e-29 40.7528978401234 3.9033487405193 10.440496237777 2.2468301513223e-23 -38.1835764935602 10.4722722708598 -3.64615964004394 0.00029185380085057 TAMM41 essential 6.17186934421358e-25 1 3.1844323734691e-19 10.440496237777 -3.64615964004394 5.50171301548206e-10 458.130378822289 68.9351846961299 6.64581346727006 7.33836289010845e-11 365.380242067875 184.572754653358 1.97960009186669 0.0482520966193861 VGLL4 other 4.57302385846869e-06 1 8.48388133725438e-07 6.64581346727006 1.97960009186669 2.1008210786886e-20 227.724606516352 32.7410707904362 6.95531945103246 1.02455836051302e-11 -341.723297785797 74.3893325839305 -4.59371372098606 5.42884546937275e-06 RAB5A other 2.50711987530698e-16 0.0665956473727956 1.21574095058475e-07 6.95531945103246 -4.59371372098606 1.0949069206609e-20 168.721552538055 79.8550941451181 2.11284645449722 0.0350704925207794 -1585.40823779486 179.003894809124 -8.85683654808415 1.17476409929343e-17 RETREG2 other 1.31388830479309e-16 1.79362982680121e-13 1 2.11284645449722 -8.85683654808415 3.81999694485258e-24 -73.0428164778503 72.2474409247419 -1.01100904811199 0.312462386961474 -1762.69315832924 164.169101250672 -10.7370579780282 1.61381834780579e-24 CTDSP1 other 4.87317010254843e-20 2.51110134918582e-20 1 -1.01100904811199 -10.7370579780282 6.20723753826449e-11 278.978308433733 40.8089870248235 6.83619782730785 2.18588673876966e-11 36.5126629852295 92.7643482367895 0.393606635299453 0.694025419400761 CNOT9 other 5.41209040961281e-07 1 2.5679797407066e-07 6.83619782730785 0.393606635299453 0.707140092638631 10.0113532802341 13.6124391833544 0.735456235681569 0.462378059340535 18.2056678335853 31.2835853761058 0.581955924000025 0.560837012474904 MARCH4 other 1 1 1 0.735456235681569 0.581955924000025 2.25683094629992e-06 50.5284772930653 18.0572323074026 2.79824041873521 0.00532035024908365 -140.961976228482 39.9708917961664 -3.52661574195855 0.000456441071969047 STK11IP other 0.0145971825606679 1 1 2.79824041873521 -3.52661574195855 1.28239330783154e-08 169.71118054213 38.3751591867725 4.42242284171757 1.18068660725614e-05 -262.414971518267 84.6002146736842 -3.10182394371505 0.00202383599467181 GMPPA other 9.84621581753055e-05 1 0.105754099411932 4.42242284171757 -3.10182394371505 0.427426872426647 2.06660300787781 2.23899886807731 0.923003149908896 0.356420086550901 7.21940288940173 6.53033932383787 1.10551726815306 0.269430560419073 GRIP2 other 1 1 1 0.923003149908896 1.10551726815306 1.49596238079545e-32 374.175518046828 32.4257170184066 11.5394678191518 1.04447185412028e-27 -286.773486389056 93.4398150973281 -3.06907163814856 0.00225430193046543 EAF1 other 2.09584329549442e-28 1 1.51855762870548e-23 11.5394678191518 -3.06907163814856 0.0523191736526071 -29.8146173397633 16.5633176817902 -1.80003897241805 0.0724262509756978 -80.1085845687132 41.2233201495702 -1.94328317753291 0.0525140145803714 CNTN4 other 1 1 1 -1.80003897241805 -1.94328317753291 1.36403396100906e-09 87.2202774106063 37.5462323061459 2.32301011455494 0.0205457953876382 -370.280596127045 76.657171833609 -4.83034512322959 1.77375495035643e-06 DYNC1LI1 other 1.10923241709257e-05 0.0222659458918242 1 2.32301011455494 -4.83034512322959 0.0397755282925263 -35.4776606369193 23.0031605051714 -1.54229505241001 0.123589871098606 -115.452611264487 47.3058172430436 -2.44055843431104 0.0149861337870627 RBMS3 other 1 1 1 -1.54229505241001 -2.44055843431104 0.00158863422350578 15.2124128803094 28.4349637594622 0.534989705244383 0.592876388147946 -184.556138460154 58.8848608513181 -3.13418654289004 0.001816590030734 OSBPL10 other 1 1 1 0.534989705244383 -3.13418654289004 2.45388017941315e-14 64.1469629180477 17.9698154947751 3.56970626307761 0.000388822872609628 -162.492092010149 34.1341288810941 -4.76039955717601 2.47685084637e-06 POMGNT2 other 2.4695850125614e-10 0.0309110985626976 1 3.56970626307761 -4.76039955717601 0.37524615480765 24.9761668662211 21.5742984072721 1.15768153358824 0.247499265670191 51.1482987361655 41.2089945169515 1.24119259243575 0.215066621025692 ACKR2 other 1 1 1 1.15768153358824 1.24119259243575 0.00628964125049788 8.68353912938078 29.7562826895977 0.291822040406156 0.770533331051584 -152.007939327127 56.8373750586098 -2.6744363048149 0.00770941196832118 FAM198A other 1 1 1 0.291822040406156 -2.6744363048149 3.63134257008688e-05 51.9091116851848 70.362925962025 0.737733841727961 0.46099429925857 -515.898191437582 137.318814085131 -3.7569374224114 0.00019057491155856 CSRNP1 other 0.2089837649085 1 1 0.737733841727961 -3.7569374224114 5.71858291323744e-33 77.3626583942835 20.9073975670757 3.70025289594682 0.000237211754983893 -394.902957465654 40.580900215188 -9.73125178031058 9.57647687915068e-21 SLC25A38 other 8.04032757601185e-29 1.47851226537207e-16 1 3.70025289594682 -9.73125178031058 0.00890569274429327 48.1660220184632 40.3941815934143 1.1923999971896 0.233625257741136 245.530081587499 79.57854604689 3.08538034161651 0.00213648817364263 ITGA9 other 1 1 1 1.1923999971896 3.08538034161651 1.08128460845954e-12 499.260797397439 138.109859414028 3.61495406277077 0.000328466880708528 -1260.16326289982 270.162969128979 -4.66445592807431 3.9040353560744e-06 GOLGA4 other 1.02040828500327e-08 0.0482070285768067 1 3.61495406277077 -4.66445592807431 9.12621576838103e-15 58.0643802335012 48.6593012818952 1.19328429927754 0.233279155991051 -683.237081071708 97.6349155534614 -6.99787649939218 7.68824265530575e-12 CTDSPL other 9.33794397420747e-11 1.11825489421422e-07 1 1.19328429927754 -6.99787649939218 2.24155497213513e-07 29.615514653466 13.6273406118773 2.17324241735425 0.0301935955139881 151.58763717869 27.0095185724585 5.61237834624952 3.18568037718709e-08 STAC other 0.00158007209985806 0.000428378440320348 1 2.17324241735425 5.61237834624952 2.23242617420012e-14 182.715526420553 38.5464639670884 4.74013716476196 2.74411409754394e-06 -517.315897995821 98.3200192168128 -5.26155204318105 2.07307671732354e-07 IQSEC1 other 2.24939261312404e-10 0.00270370665473336 0.0256931402953039 4.74013716476196 -5.26155204318105 0.00177864980944436 32.6972387774267 14.3250469657556 2.28252227413916 0.0228501035656749 118.805595422847 36.7427342153485 3.23344459686994 0.00129849809331955 CAND2 other 1 1 1 2.28252227413916 3.23344459686994 1.15635997115471e-10 1906.05403743249 372.20270263074 5.12101073947191 4.25015840800883e-07 -3099.32351788058 954.646113350796 -3.24656799471166 0.00124134014572316 RPL32 essential 9.93928177790681e-07 1 0.0041902311744559 5.12101073947191 -3.24656799471166 6.1420187593183e-06 -85.5336935964839 60.0222100415632 -1.4250340588468 0.154730456290317 -556.934367542117 114.741240698225 -4.85382905181305 1.59145452812275e-06 PTPRG other 0.0380006700639023 0.0200220894183123 1 -1.4250340588468 -4.85382905181305 0.994231388351434 -5.26785714285712 55.9865207349987 -0.0940915254904211 0.925070970002861 0.0903600464576054 104.208627780367 0.00086710715208774 0.999308465386696 IL17RD other 1 1 1 -0.0940915254904211 0.00086710715208774 2.71639415779527e-29 59.804621365182 15.1283999793717 3.95313591964309 8.73544645723292e-05 -259.010270654385 29.7363370838133 -8.71022782410463 3.6786509204956e-17 SHQ1 essential 3.69320949693845e-25 5.6018496217307e-13 0.725653537202338 3.95313591964309 -8.71022782410463 5.17958613868946e-26 48.5326137964767 54.1747652182147 0.895852775752482 0.370735804603686 -1019.86018803605 105.179902476095 -9.69634087907475 1.39125994194248e-20 SLC25A26 essential 6.79147334504962e-22 2.14657496442305e-16 1 0.895852775752482 -9.69634087907475 1.27490533984366e-22 174.314675417923 31.8638646686238 5.47060682157523 6.89729931035172e-08 -349.98421586434 62.5412412623739 -5.59605483997481 3.50573325324263e-08 UBA3 essential 1.58802209130927e-18 0.000470784918577953 0.000711387450869676 5.47060682157523 -5.59605483997481 8.24274850271328e-22 217.396907265599 108.28733703848 2.0075930686923 0.0451889034597066 -1731.90149032937 212.542469088891 -8.1484961464574 2.62170431546273e-15 ARL6IP5 other 1.01196223367811e-17 3.94776235822378e-11 1 2.0075930686923 -8.1484961464574 1.46026730440712e-19 108.666154646534 51.4734722969893 2.1111098551805 0.0352261243103879 -759.913296096035 101.030269963081 -7.52163976572298 2.30098277866395e-13 TMF1 other 1.71391573518263e-15 3.40361372619971e-09 1 2.1111098551805 -7.52163976572298 4.48374727271482e-19 115.692084181968 256.127214277169 0.451697741329322 0.651670145375795 -4132.67011425612 496.657792079894 -8.32096099197276 7.32752358109134e-16 LRIG1 other 5.19576633962193e-15 1.10711553786709e-11 1 0.451697741329322 -8.32096099197276 1.99996211157059e-19 70.8444544001201 44.0101187347277 1.60973104451586 0.10803244568586 -627.762766253624 82.2542330735639 -7.63198127070477 1.03218536710571e-13 LIMD1 other 2.34015566674875e-15 1.53279527015199e-09 1 1.60973104451586 -7.63198127070477 0.0911363270022557 -1.75195885888751 2.54743403367317 -0.687734730607076 0.491915681382086 -10.5434273019982 4.88476287870986 -2.15843175273698 0.0313350798626852 ZNF660 other 1 1 1 -0.687734730607076 -2.15843175273698 0.781755451492164 49.6409634528386 89.6478552216335 0.553732862098182 0.579994331860214 -112.853915308578 312.931052812354 -0.360635080137764 0.718515408363337 NFKBIZ other 1 1 1 0.553732862098182 -0.360635080137764 0.172581762952181 -15.1879039434363 143.87709254867 -0.105561654564979 0.915969205121338 -905.452305735308 484.49137442045 -1.86887187995537 0.0621797810916117 COL8A1 other 1 1 1 -0.105561654564979 -1.86887187995537 0.000260299184585796 143.840205750605 52.7382572145534 2.72743570507885 0.00659210109715256 -499.709785574674 185.202879365131 -2.69817503533239 0.00719185605703923 NXPE3 other 1 1 1 2.72743570507885 -2.69817503533239 0.2885238948392 10.8668138313907 7.82109618331486 1.38942337195308 0.165272455127235 -15.4566434510651 27.4900220803295 -0.562263769956195 0.57416792141574 ADGRG7 other 1 1 1 1.38942337195308 -0.562263769956195 0.340108294364187 -8.88231335423201 47.4773976338483 -0.187085093052773 0.85166392539484 -237.596000475778 161.624445711685 -1.47004990135969 0.142128478349567 PHLDB2 other 1 1 1 -0.187085093052773 -1.47004990135969 3.934276549805e-09 48.9353462759607 15.7685335904924 3.10335428434932 0.00201302219902645 -270.817936267409 53.692340513517 -5.04388398191042 6.22921276147933e-07 ABHD10 other 3.12065414270613e-05 0.00798335907511191 1 3.10335428434932 -5.04388398191042 0.709669556084758 -2.83838754966586 7.89856621599038 -0.359354783140216 0.719469654397223 -19.9471087001645 25.1077577544876 -0.794459979071577 0.427275416743185 PLA1A other 1 1 1 -0.359354783140216 -0.794459979071577 8.83171729111189e-08 51.8176218568273 22.8137092708194 2.27133699486152 0.0235171311765645 -356.775110648469 73.4583769535284 -4.85683356268781 1.56236928648223e-06 RABL3 other 0.000641006040988901 0.019659292731806 1 2.27133699486152 -4.85683356268781 0.389237204715441 12.3236227177411 9.09579128806025 1.35487087681068 0.17602314357607 -0.390749854128249 28.9134658115113 -0.013514459203043 0.98922232288293 ADPRH other 1 1 1 1.35487087681068 -0.013514459203043 6.0439879932226e-21 176.753932983352 19.0752041418176 9.26616206407266 4.46639396095013e-19 -163.782205831223 63.9743244053838 -2.56012403965988 0.0107324624934917 ATG3 other 7.29751110301697e-17 1 6.07831554145704e-15 9.26616206407266 -2.56012403965988 0.0371406258004804 123.419565012603 59.3356090284034 2.08002525015835 0.03799164743644 -239.166311051378 200.70157932903 -1.19165136542991 0.233918545464713 BOC other 1 1 1 2.08002525015835 -1.19165136542991 3.17176481398262e-10 318.187054072629 48.5125330875821 6.55886291276917 1.26136119918344e-10 -78.5250606205237 169.871527540392 -0.462261461691113 0.644078315782833 SRPRB essential 2.66777138504078e-06 1 1.44930401786178e-06 6.55886291276917 -0.462261461691113 0.157138708320592 19.7515757324502 10.4450239373531 1.89100339558011 0.0591559334220685 24.8797039552629 36.4491912312877 0.682585898748457 0.495159636105263 TMEM108 other 1 1 1 1.89100339558011 0.682585898748457 0.0271991540401362 -193.240302451752 135.08435029315 -1.43051583719651 0.153144208178183 -1245.56489269528 526.523168105271 -2.36564118759965 0.0183492261190324 AGTR1 other 1 1 1 -1.43051583719651 -2.36564118759965 0.0583057778063571 12.0377857745743 5.65874855634047 2.12728762459084 0.0338437569973706 -28.7151365863314 26.5194531012273 -1.08279520232649 0.279377283942475 MED12L other 1 1 1 2.12728762459084 -1.08279520232649 4.09723522015876e-13 299.147210375482 41.6669606200951 7.17948239860841 2.31377218210436e-12 -416.40717961173 170.071829995449 -2.44841946854381 0.0146637375768513 EIF2A other 3.92719995852217e-09 1 2.79040925161786e-08 7.17948239860841 -2.44841946854381 0.210999112530349 47.0079274930192 28.058444355219 1.67535758212039 0.0944408671819179 79.6825671092795 90.1721414955476 0.883671672732913 0.377265269966064 ALDH1L1 other 1 1 1 1.67535758212039 0.883671672732913 1.10722298001244e-15 111.683838258748 14.020719060894 7.96562842274275 9.70549069079554e-15 -69.5382731367493 44.5936286598189 -1.55937687123916 0.119489815936093 OSBPL11 other 1.16878457770114e-11 1 1.23570307475209e-10 7.96562842274275 -1.55937687123916 0.339381865105542 4.93056830731975 4.28983301123356 1.14936136078219 0.25091022107346 -11.3682554255984 15.1149280388032 -0.752121041953601 0.452302374123049 TRPC1 other 1 1 1 1.14936136078219 -0.752121041953601 0.000486846726959335 92.4361983510168 31.4156715633419 2.94235945791075 0.00339898070191561 -328.933781971372 132.779119786096 -2.47730051608472 0.0135469859019557 NCEH1 other 1 1 1 2.94235945791075 -2.47730051608472 7.42182342736235e-25 8.16826252118346 1.74650023013552 4.67693183215306 3.69854344438784e-06 -18.8541565185309 3.7441632240025 -5.035612870097 6.53594308879323e-07 FAM86B2 other 9.57637876832565e-21 0.00836862153089086 0.0343409758811411 4.67693183215306 -5.035612870097 0.0179337937393767 264.910323505536 106.155327830115 2.49549720132262 0.0128754305694771 -627.81264583826 455.669745227974 -1.37777996545319 0.16884192498452 LPP other 1 1 1 2.49549720132262 -1.37777996545319 7.36646703061692e-05 23.9292572526987 6.06640375607146 3.94455400841883 9.0390980925545e-05 -59.6318736619814 28.2775815898863 -2.10880387604678 0.0354171547798153 TMEM44 other 0.407733950144647 1 0.749612404815545 3.94455400841883 -2.10880387604678 4.95986815182668e-07 16.9635020550953 10.3507562350391 1.63886596011902 0.101844865344971 -70.9752076517611 18.749244983471 -3.78549684077046 0.000171243922227669 AMT other 0.00339750968400128 1 1 1.63886596011902 -3.78549684077046 1.39365048714612e-12 138.789480311127 50.2665113253895 2.7610724645819 0.0059639874613105 -445.738510694448 90.9699134877775 -4.89984538409324 1.28179548555607e-06 TCTA other 1.30989209286864e-08 0.0161967677554865 1 2.7610724645819 -4.89984538409324 6.0976810216919e-33 61.7349018999318 16.5732296809415 3.72497715221581 0.000216616433485664 -276.93387120149 30.0360063149539 -9.22006302361223 7.29086838750501e-19 NICN1 other 8.57272974839664e-29 1.11820048459164e-14 1 3.72497715221581 -9.22006302361223 5.33084330160294e-29 159.65563417874 36.7611785401096 4.34304993798123 1.69405682340467e-05 -524.880181032585 67.3599839706577 -7.7921660619935 3.68535711590211e-14 DCAF1 other 7.22862351697359e-25 5.49191917411733e-10 0.149703801484271 4.34304993798123 -7.7921660619935 2.14897473339509e-05 226.151588490647 55.7764035357589 4.05461044733118 5.78782279356787e-05 -6.08114632553454 102.16131315493 -0.0595249428353797 0.952556780079466 MANF other 0.126531632302303 1 0.48901314782855 4.05461044733118 -0.0595249428353797 0.44093197373276 2.9023953695429 5.06093072791638 0.573490435965291 0.566548372378031 20.3295228846463 16.4611615783625 1.23499929138467 0.217360978000963 EAF2 other 1 1 1 0.573490435965291 1.23499929138467 7.353661812689e-06 14.4335846606382 10.9339703641814 1.32006802468764 0.187363435699487 -157.54565264355 35.7333554480604 -4.40892411776296 1.2506158332404e-05 ILDR1 other 0.04523237380985 0.150123924622177 1 1.32006802468764 -4.40892411776296 0.778138368712358 3.65124438693435 5.95316658127859 0.613328106493226 0.539918134063993 9.98408069874772 28.1236467260426 0.355006617598507 0.722723500588104 TM4SF19 other 1 1 1 0.613328106493226 0.355006617598507 0.566842117600242 2.5955702377929 3.15894299924335 0.821657826182557 0.411633616582006 -27.550551185963 42.3539709357141 -0.650483309529109 0.515656224533079 MUC4 other 1 1 1 0.821657826182557 -0.650483309529109 3.4365330041419e-05 -119.58660965763 31.8154348484595 -3.75876080987842 0.000189191654711484 -239.729649492636 57.6656089686567 -4.15723780222173 3.74054889092888e-05 SLIT2 other 0.198150493018822 0.434763997592663 1 -3.75876080987842 -4.15723780222173 8.54142654204099e-31 280.866692572618 22.7255316405159 12.3590812754355 4.55555432793394e-31 -279.274959248724 100.159190192261 -2.78831087504443 0.00548552403360964 EIF2B5 essential 1.17666692043157e-26 1 6.72445374346328e-27 12.3590812754355 -2.78831087504443 5.68491786931992e-18 105.768338158462 11.6723066946811 9.06147695782007 2.42755749311905e-18 73.8786679893446 51.3476082535256 1.4387947268074 0.150794540898793 ECE2 other 6.41201886480594e-14 1 3.27623159271347e-14 9.06147695782007 1.4387947268074 0.0768207551513331 11.0144632439512 4.90064428439073 2.24755411835007 0.0250097292246651 -9.02874234386787 21.3912318318237 -0.422076784303549 0.673137898300763 VWA5B2 other 1 1 1 2.24755411835007 -0.422076784303549 2.11701876824419e-30 158.386378813691 18.7232921517474 8.45932315374935 2.86856645152992e-16 -194.113410471406 41.8900412674741 -4.63387966681539 4.5649197377001e-06 DGKQ other 2.90624336504562e-26 0.0561895970513505 3.75151120531083e-12 8.45932315374935 -4.63387966681539 2.53607591554814e-31 190.32701071739 23.889747416371 7.96689087583086 1.02423770229526e-14 -364.866851229295 59.0164049015253 -6.18246488985752 1.27208996019419e-09 FIP1L1 essential 3.51474761135817e-27 1.77812734635944e-05 1.30344489994094e-10 7.96689087583086 -6.18246488985752 6.18429751960777e-31 54.5388037657527 6.09086291805002 8.95419983991582 6.33053829077105e-18 -56.1156540515814 13.6450949399039 -4.11251473871947 4.55888482769858e-05 SLC26A1 other 8.53804115557049e-27 0.527508563413003 8.50444513982183e-14 8.95419983991582 -4.11251473871947 8.44250830900118e-12 90.6470613863155 13.8784971833241 6.5314752879176 1.49062769440797e-10 162.678442921316 26.7166767420117 6.08902239197684 2.1408294462119e-09 LYAR other 7.68099405952928e-08 2.97725151084689e-05 1.70766308671377e-06 6.5314752879176 6.08902239197684 2.10775712623873e-12 27.8466341142051 14.0135535398636 1.98712154165546 0.0474242285059048 -202.301676417529 34.2806974478536 -5.90132907083533 6.44462387249458e-09 CENPC essential 1.96569429593024e-08 8.85749105035656e-05 1 1.98712154165546 -5.90132907083533 0.18172039502058 -22.6557133566611 13.2289242379063 -1.71258924378319 0.087363255696507 -40.2813453737244 29.4755308700201 -1.36660287990589 0.172319592658506 CORIN other 1 1 1 -1.71258924378319 -1.36660287990589 0.000353511265096677 5.73649496985911 26.0400752026694 0.220294869550571 0.825724774108926 -202.400107562894 57.3440080948347 -3.52957727036045 0.000451744599246355 ATP10D other 1 1 1 0.220294869550571 -3.52957727036045 2.71212591977097e-10 257.774500622519 44.7659558942589 5.75827088851638 1.43934487065763e-08 -80.5753533244628 98.670528236215 -0.816610134401706 0.414517460700058 OCIAD2 other 2.28984791406263e-06 1 0.000153189474584091 5.75827088851638 -0.816610134401706 0.14267072736472 -1.18235672903861 1.58218526807773 -0.747293476240685 0.455208716451465 -7.66869605909501 3.87903096036924 -1.97696180758635 0.048549517225905 SLC10A6 other 1 1 1 -0.747293476240685 -1.97696180758635 0.000148170127031019 197.463052137208 46.8921667530331 4.21100294164666 2.97932799772724e-05 218.544646572739 109.288878321335 1.99969704081111 0.0460343758033888 SCD5 other 0.787079714788772 1 0.258635463482702 4.21100294164666 1.99969704081111 0.110320065236498 -6.55151501769944 3.15894422514317 -2.07395716757314 0.0385584039878929 -3.47089309288956 7.43147274432887 -0.467053195551081 0.640650910626596 PLAC8 other 1 1 1 -2.07395716757314 -0.467053195551081 5.73986426973641e-27 349.966124746559 36.0554422087335 9.7063328947825 1.22454012150051e-20 -190.610849881329 83.4040998469489 -2.28538945005234 0.022676721001948 ENOPH1 other 7.61220799452443e-23 1 1.69402880408381e-16 9.7063328947825 -2.28538945005234 4.14282082342636e-18 26.3036142861719 7.1641300059658 3.67157132328253 0.000264852873961683 -103.888299343796 16.1195862302637 -6.44484900913594 2.55241905837126e-10 TRMT10A other 4.68801604378927e-14 3.62239312764049e-06 1 3.67157132328253 -6.44484900913594 3.27360676744521e-16 95.0737142951919 15.0405428548932 6.32116242162504 5.39165452764843e-10 -120.14230343066 36.7908858416941 -3.2655452751971 0.00116091434834961 KLHL8 other 3.51290742214545e-12 1 6.06291551634066e-06 6.32116242162504 -3.2655452751971 0.525124009209828 -5.23052537888334 4.78336600852595 -1.09348215661531 0.274666122870253 -1.16312795008505 10.9481521638987 -0.106239658772778 0.915431370142701 SNCA other 1 1 1 -1.09348215661531 -0.106239658772778 2.45115064647242e-14 278.388295836296 38.8656605974809 7.16283453199146 2.55941549511805e-12 -112.897354087268 95.7132968637125 -1.17953678106005 0.238696316628067 PYURF other 2.46708312567449e-10 1 3.08383973006774e-08 7.16283453199146 -1.17953678106005 7.72136762036376e-24 122.473611819688 24.5290566279378 4.99300130768969 8.04458551118223e-07 -363.274950763782 53.2098825599985 -6.82720827948004 2.3440256521283e-11 TBCK other 9.80304833081382e-20 3.38524184680369e-07 0.00778876769192664 4.99300130768969 -6.82720827948004 0.00693694103368991 193.013642551095 63.1755588539746 3.05519485782834 0.00236001568264459 69.6997479051842 137.431407147234 0.507160257993379 0.612249038527069 CAMK2D other 1 1 1 3.05519485782834 0.507160257993379 2.12593553750821e-29 203.211235248947 19.8144199809767 10.2557246411474 1.13392836639508e-22 -97.4386513301385 44.9093790355167 -2.16967264795799 0.0304662336959529 CISD2 other 2.89297307944117e-25 1 1.59600417570108e-18 10.2557246411474 -2.16967264795799 0.345417187154797 12.7808648210126 15.3831487323609 0.830835418897433 0.406431774971753 48.6894470086701 34.0696440015653 1.42911522663498 0.15354613342574 DDIT4L other 1 1 1 0.830835418897433 1.42911522663498 0.835716315597087 -19.3580697637822 33.501058439418 -0.577834571966988 0.563615787704592 -28.538977727741 72.7964965596639 -0.392037791329018 0.695184393932829 ANK2 other 1 1 1 -0.577834571966988 -0.392037791329018 0.000395062525264529 100.27854429387 29.2352855284878 3.43005181858597 0.000649001562854159 -22.2884558306626 63.3763228638401 -0.35168426982657 0.725210491015021 TIFA other 1 1 1 3.43005181858597 -0.35168426982657 1.99772043193485e-10 58.7827884202277 12.5299941238908 4.69136600057514 3.44452083824731e-06 -91.200613204826 30.1175966595099 -3.02815042766796 0.00257834253594764 SPATA5 other 1.7016582639221e-06 1 0.0320340437957 4.69136600057514 -3.02815042766796 4.96797807789184e-28 437.938436250751 37.5956631174553 11.6486424214026 3.84664070093307e-28 574.463969258829 91.6514202548521 6.26792217361647 7.47139099064787e-10 CCNA2 essential 6.66951056956979e-24 1.04973043418603e-05 5.60763281382023e-24 11.6486424214026 6.26792217361647 3.06125189842536e-31 90.4795761277231 17.6491460525965 5.12656962881284 4.11492149306914e-07 -315.844860702025 37.2452502322849 -8.48013797013623 2.15347875202339e-16 METTL14 essential 4.23952775412928e-27 3.26402774444185e-12 0.00406101602150993 5.12656962881284 -8.48013797013623 0.00053506726599174 11.1825717306907 55.404803604666 0.201833974730469 0.840122389841748 -408.41757998267 116.910413136946 -3.4934234601007 0.000515909314430185 USP53 other 1 1 1 0.201833974730469 -3.4934234601007 3.64683729279744e-14 518.965038284104 111.565882522451 4.65164642228029 4.14634728442058e-06 -1091.01195736753 245.188640386358 -4.44968394803429 1.0449749123214e-05 SETD7 other 3.64829602771456e-10 0.126034424175084 0.0383578587281748 4.65164642228029 -4.44968394803429 0.000279838531339192 55.936049317566 28.7269332944113 1.947163964364 0.052032131142152 -165.704073756386 64.4612870598044 -2.57059828176643 0.0104186017491209 NAF1 essential 1 1 1 1.947163964364 -2.57059828176643 0.18898616995528 -5.58420911693498 15.1438774407717 -0.368743681317751 0.712463043575567 -61.494694850905 34.127590963979 -1.8019055290428 0.0721168282488817 MARCH1 other 1 1 1 -0.368743681317751 -1.8019055290428 3.64447016582232e-05 -2531.70983663588 631.440832216135 -4.0094173633822 6.93045760415059e-05 -5060.74420789617 1438.4837279656 -3.51811015273244 0.000470712535292026 SFRP2 other 0.209702813341416 1 0.580910956379903 -4.0094173633822 -3.51811015273244 1.77656948863543e-05 107.222201599324 135.285182469918 0.792564267880303 0.428381081231658 -1232.805930729 307.444750459232 -4.00984544015647 6.93466451199919e-05 RPS3A essential 0.105652587489149 0.790967834238628 1 0.792564267880303 -4.00984544015647 0.00147225682342229 0.682550439291229 1.95101602896118 0.349843583629937 0.726590743883745 15.5315331535471 4.45195034879052 3.48870313833725 0.000524455079493976 RNF175 other 1 1 1 0.349843583629937 3.48870313833725 0.0691684698745349 60.3572697379046 34.9498313552151 1.72696884069222 0.0847419574384054 -60.7139889262422 78.13735418607 -0.777016185903387 0.437487581716169 PDGFC other 1 1 1 1.72696884069222 -0.777016185903387 6.18714576235159e-26 39.5864953271465 25.4487601187475 1.55553728914219 0.120405102847307 -522.497389659365 53.7876328082371 -9.71408040064089 1.15506048813837e-20 CBR4 other 8.10577966325682e-22 1.7830668755392e-16 1 1.55553728914219 -9.71408040064089 0.0373167045605779 176.609911381855 131.138782286304 1.34674051644218 0.178627714834432 -394.222575606864 279.663375402877 -1.40963247346549 0.159222821521257 GLRA3 other 1 1 1 1.34674051644218 -1.40963247346549 9.33023825481553e-11 30.6184537275488 34.7875109282665 0.880156496125449 0.379163188087416 -426.738789861276 73.0261523465174 -5.84364335445679 8.80373464081096e-09 CYP4V2 other 8.05479468538225e-07 0.000120575949640547 1 0.880156496125449 -5.84364335445679 0.316824714720457 1.16472906461125 2.71285688053815 0.429336716200157 0.667848184891122 -18.3382883418845 13.2757912382441 -1.38133298519011 0.167743694316882 ROPN1L other 1 1 1 0.429336716200157 -1.38133298519011 9.33681328773826e-12 326.936311553223 46.2074492295487 7.07540271113157 4.77030457559991e-12 -167.26249720407 211.034953380376 -0.792581961067796 0.428378067378711 NDUFS6 other 8.47876014659512e-08 1 5.71005457699309e-08 7.07540271113157 -0.792581961067796 5.99917232263339e-16 598.357384556446 84.5876802125753 7.07381243997622 4.6580775233667e-12 -1630.14990611867 413.943098836361 -3.93810142191329 9.28068360559693e-05 MARCH6 other 6.38611893744324e-12 1 5.57711621872694e-08 7.07381243997622 -3.93810142191329 0.625206242169419 5.38003601918196 9.02089725161327 0.596396995677987 0.551167109480324 -27.6855351169388 41.3659794640916 -0.669282716754517 0.503609361414125 NKD2 other 1 1 1 0.596396995677987 -0.669282716754517 0.444700680266048 -4.65161796148805 3.99618961984304 -1.16401332368977 0.244937442406244 -13.3249404871392 19.522785149771 -0.682532762867369 0.49519754669834 CDH18 other 1 1 1 -1.16401332368977 -0.682532762867369 0.178546362894922 -34.5810040549474 19.1006413440994 -1.81046298037684 0.0707796931189403 -56.7996306037212 84.0776663039791 -0.675561455266427 0.49960830573882 ADAMTS16 other 1 1 1 -1.81046298037684 -0.675561455266427 0.000198589191965471 176.287741540383 43.9834270152844 4.00804924725676 6.98104137714617e-05 328.829746163661 199.268942553296 1.65018061495315 0.0994864088669972 SRD5A1 other 1 1 0.584732025749763 4.00804924725676 1.65018061495315 1.90121902759591e-21 889.176225413064 92.3457178443554 9.62877593210907 2.33591163843825e-20 2181.39549499567 465.032488954362 4.69084536416067 3.45146826852356e-06 MYO10 other 2.31663538512562e-17 0.0427222742277847 3.22355806104478e-16 9.62877593210907 4.69084536416067 0.439412037522485 4.66007922176826 22.7497931575563 0.204840509515596 0.837773495534247 -140.740101829191 114.7080837003 -1.22694144378617 0.220376308452538 FAM105A other 1 1 1 0.204840509515596 -1.22694144378617 3.77404204284939e-05 1681.27618068453 395.848594887264 4.24727080605995 2.54674901046461e-05 -1575.83688138203 1838.46825197686 -0.857146638070888 0.391742678531468 RPL37 essential 0.216775411583634 1 0.222076513712514 4.24727080605995 -0.857146638070888 1.13735665805855e-08 110.945712860144 21.3861526081442 5.18773595667198 3.0125516600897e-07 430.769049122585 107.403134798208 4.01076793458519 6.90179367367354e-05 SKP2 other 8.76674512031533e-05 0.787356622292678 0.00299628388112521 5.18773595667198 4.01076793458519 0.0721232392425531 65.5895663378629 67.5739476098913 0.970633930054163 0.332166770498822 -586.086454529044 314.240498150568 -1.86508886657958 0.0627131179464661 OSMR other 1 1 1 0.970633930054163 -1.86508886657958 2.27717109931604e-07 92.1636791655597 189.380588684113 0.486658531404656 0.626698896350611 -2133.8739091898 435.862127460443 -4.89575435613746 1.29733398905314e-06 PLK2 other 0.00160381160524829 0.0163918149516864 1 0.486658531404656 -4.89575435613746 0.618484193664203 -2.04478789662803 9.7231483348704 -0.210301008089608 0.833512074379293 17.9274024831087 22.7198752069327 0.789062541929739 0.430421749122764 GZMA other 1 1 1 -0.210301008089608 0.789062541929739 0.00021819202000318 -0.202991739225711 206.967822687777 -0.000980788881042323 0.999217808053624 -1713.09221637484 453.873741109494 -3.7743805406922 0.000178278618033846 PIK3R1 other 1 1 1 -0.000980788881042323 -3.7743805406922 0.00452566648191239 -5.33187852233459 48.3307937273713 -0.110320524682693 0.912195791873173 322.392563482614 107.988580837819 2.98543198717272 0.00295894235321126 HAPLN1 other 1 1 1 -0.110320524682693 2.98543198717272 0.488365969005601 -39.2059075888881 62.0791044049367 -0.631547570872661 0.527948325977897 91.2235013196563 137.421953562266 0.663820437382466 0.507086989660097 LHFPL2 other 1 1 1 -0.631547570872661 0.663820437382466 4.16671100244811e-19 136.228876653252 36.8903550017254 3.69280470862588 0.000244179518171743 -560.93460829785 83.7145052306384 -6.70056648787975 5.19726735170566e-11 SSBP2 other 4.83380143394005e-15 7.46327591704933e-07 1 3.69280470862588 -6.70056648787975 0.000126494332881761 1.17487996867853 1.23816412291835 0.948888719137929 0.343097006880044 -10.2067263988508 2.93995560384845 -3.47172807150219 0.000558065512263592 ANKRD31 other 0.679780544906583 1 1 0.948888719137929 -3.47172807150219 4.83503509030274e-10 77.7239366600477 113.64888244307 0.683895300941317 0.494333561772171 -1443.58973478493 251.549370437457 -5.73879287503069 1.58796472531312e-08 IQGAP2 other 4.0309687547854e-06 0.0002157885265228 1 0.683895300941317 -5.73879287503069 0.00302949419538985 11.3953362608939 3.58713662072568 3.17672212289161 0.00157446139597525 1.25229372532785 7.96040812211456 0.157315266518672 0.875055083227141 CRHBP other 1 1 1 3.17672212289161 0.157315266518672 8.78443826669333e-11 44.4364995084948 70.163409423535 0.633328680484409 0.52678567680424 -945.738651199422 155.587723336111 -6.0784914832668 2.28685976098268e-09 RASA1 other 7.59326843772971e-07 3.17736295190934e-05 1 0.633328680484409 -6.0784914832668 2.25997548736737e-41 21.2914877779199 3.97096164240586 5.36179638467124 1.21901251802089e-07 -94.4806812684989 8.84004107706879 -10.6878102086633 2.46073850333036e-24 GIN1 other 3.32803990269719e-37 3.82767874193038e-20 0.00123839481705743 5.36179638467124 -10.6878102086633 5.87172898527414e-12 72.1309803980549 37.6095778290221 1.91788859545224 0.0556474101973927 -483.233954055351 83.7253649970637 -5.77165538869013 1.31834200727078e-08 PPIP5K2 other 5.38437547949639e-08 0.000179663648750862 1 1.91788859545224 -5.77165538869013 0.486450154595541 307.902829888392 271.555320258975 1.13384937402351 0.257356232189115 491.673869888874 604.528676416904 0.813317695370664 0.416391099451327 PAM other 1 1 1 1.13384937402351 0.813317695370664 7.39282223657944e-10 91.9148281033855 43.9371205070327 2.09196294710923 0.0369179804246309 -533.517859332817 106.774545748271 -4.99667646061099 7.93917563955389e-07 BDP1 essential 6.09612121628341e-06 0.0101303881160708 1 2.09196294710923 -4.99667646061099 3.72020000783442e-07 115.673884081311 40.1565832770491 2.88057087136252 0.00413399964135829 -301.819545079189 93.5715469585755 -3.22554830917571 0.00133670967504255 GTF2H2 essential 0.00257921466543161 1 1 2.88057087136252 -3.22554830917571 1.29638152330165e-22 181.379092896254 42.2365204007396 4.29436637240311 2.08003876806619e-05 -642.473769408163 90.9476061479308 -7.06421858276453 5.04151343214924e-12 SLC30A5 other 1.61425427281522e-18 7.34951828138717e-08 0.182627403836212 4.29436637240311 -7.06421858276453 1.47439779963115e-44 1085.66911612482 228.511863844229 4.75104048367876 2.58952751912521e-06 -6389.38883395937 538.877659785549 -11.8568449033535 5.0724883197927e-29 BTF3 other 2.19817967947009e-40 7.93235723449183e-25 0.0243053052945093 4.75104048367876 -11.8568449033535 5.85401060280611e-34 111.050345054852 23.3811706473851 4.74956308773493 2.61005508161357e-06 -493.138093284125 51.5199563802527 -9.57178786496686 3.63682233387358e-20 FBXL17 other 8.28693740933233e-30 5.60361585203242e-16 0.0244875367756985 4.74956308773493 -9.57178786496686 2.30161234663489e-19 6.01147240105252 0.785915663563132 7.64900444126296 9.25484694534188e-14 -4.38197897074918 1.82505301505698 -2.40101461962866 0.016684360528187 SPATA9 other 2.69012451074686e-15 1 1.15296883245069e-09 7.64900444126296 -2.40101461962866 0.694363649101036 1.48476718303636 1.75727986817771 0.844923571892994 0.398524269725935 1.71768310448245 3.90466090829874 0.43990583172838 0.660179706536736 TSLP other 1 1 1 0.844923571892994 0.43990583172838 0.931051467003886 -1.42564971481754 17.3144180620278 -0.0823388755954861 0.934407639250876 -14.6226843910151 39.2116221705694 -0.37291709910411 0.709355936753483 TNFAIP8 other 1 1 1 -0.0823388755954861 -0.37291709910411 3.29854257969941e-15 76.020933048412 41.0345576898549 1.85260759048481 0.064483048090568 -637.015144119466 92.1509728962121 -6.91273378998313 1.34347059935785e-11 FEM1C other 3.42883501159754e-11 1.94762932788907e-07 1 1.85260759048481 -6.91273378998313 7.13443458083558e-32 73.1411202169096 16.7587928238261 4.36434300404528 1.5282376595313e-05 -358.408937254118 37.81033474479 -9.47912626728343 8.04043462795469e-20 COMMD10 other 9.93113293652313e-28 1.2379053153199e-15 0.135585245153617 4.36434300404528 -9.47912626728343 2.45752150415955e-33 122.375459906196 20.6655691560062 5.92170769565418 5.67280114560029e-09 -398.944717582682 46.3270777023145 -8.61148031279234 7.93807243030411e-17 ATG12 other 3.46485956871455e-29 1.20650762868192e-12 6.13229803839391e-05 5.92170769565418 -8.61148031279234 0.664116772362434 32.7293390912845 37.3121040453288 0.877177525328594 0.380776009250367 46.7747612030054 86.4463303394674 0.541084404847781 0.588670091306435 MEGF10 other 1 1 1 0.877177525328594 0.541084404847781 0.0211027535095244 8.07087978988882 8.91013993698458 0.905808421300756 0.365437535308158 -44.2344840478054 21.0652736621227 -2.09987701832438 0.036198765709448 ADAMTS19 other 1 1 1 0.905808421300756 -2.09987701832438 6.22315700984957e-14 113.021729041532 30.2602924502055 3.7349846908292 0.000207495722406463 -371.682005236406 69.8357174536953 -5.32223364760089 1.49999634248322e-07 YIPF5 other 6.1721271223688e-10 0.00197054519512021 1 3.7349846908292 -5.32223364760089 0.605242257312357 -32.6537207699826 34.2997159467431 -0.952011405012329 0.341513209200894 -50.479214624079 79.5323486695048 -0.63470041396419 0.525890168423406 ARHGAP26 other 1 1 1 -0.952011405012329 -0.63470041396419 0.0303889961952658 577.337734412734 1687.26291244888 0.342174139046765 0.732351757365573 -9001.83276434696 3877.6937396978 -2.32143984765762 0.0206309711134163 CXCL14 other 1 1 1 0.342174139046765 -2.32143984765762 0.0375289969981582 36.3260319071115 25.9533031508263 1.39966892445268 0.162181421941757 -89.0344053584462 59.6462829888032 -1.49270668509486 0.136092626587638 SLC25A48 other 1 1 1 1.39966892445268 -1.49270668509486 4.9678177256895e-08 184.055325843085 48.1377580124028 3.82351263213511 0.000146753506714517 -303.641911863883 111.186694162123 -2.73091950572015 0.00652032439005576 DDX46 essential 0.000367966258941822 1 1 3.82351263213511 -2.73091950572015 0.0105656882919189 42.6121259525231 68.6248524186314 0.620943061452094 0.534896208577285 483.29148433769 161.193634319362 2.99820452822706 0.00283942045700824 RNF145 other 1 1 1 0.620943061452094 2.99820452822706 0.979065811419357 0.846453795765287 4.16705481918243 0.203129988083852 0.839109109328252 0.979027359729739 9.80253379189361 0.0998749283108174 0.920480280753812 C1QTNF2 other 1 1 1 0.203129988083852 0.0998749283108174 0.113048574533354 -0.494934062544204 3.450559970867 -0.143435867431061 0.88599887785458 -16.3505341145034 8.14505663804418 -2.00741809923491 0.0451974461979605 GABRB2 other 1 1 1 -0.143435867431061 -2.00741809923491 8.21589625093461e-31 101.919032039886 23.5302318273205 4.33140790060341 1.76231793625435e-05 -532.359862884648 55.6421422494506 -9.56756590172271 3.7009305116295e-20 FBXO38 other 1.13198618545377e-26 5.70202363926757e-16 0.155524557874447 4.33140790060341 -9.56756590172271 5.11837878966814e-17 36.3540004826535 11.425388398116 3.18186123883964 0.0015462096248258 -183.85745044283 27.1823107387156 -6.76386390436495 3.45521368910872e-11 PCYOX1L other 5.62458645196632e-13 4.97619875505439e-07 1 3.18186123883964 -6.76386390436495 0.00053683344499178 184.790127068725 73.4208033950391 2.51686332107354 0.012125308988004 -332.06396613734 171.639920530216 -1.93465462528505 0.053547969053177 TNIP1 other 1 1 1 2.51686332107354 -1.93465462528505 1.744073043222e-05 475.457224907434 110.770844560166 4.29225963560462 2.09277573201769e-05 -97.3055937659438 259.901425822673 -0.374394228342302 0.7082563937975 G3BP1 other 0.103772346071709 1 0.183661998241872 4.29225963560462 -0.374394228342302 0.000333650416080958 3.48459371244066 9.26155231288931 0.376242944456638 0.70688244333568 84.6435889637046 21.7303629037854 3.89517604185799 0.000110295848486368 ZNF300 other 1 1 1 0.376242944456638 3.89517604185799 6.02137697216681e-11 194.950404267421 53.7499052597344 3.62699065840892 0.00031388164114296 -642.460313955214 146.483122504564 -4.38589991099621 1.38867883242845e-05 N4BP3 other 5.25244713282111e-07 0.166252629818334 1 3.62699065840892 -4.38589991099621 2.65942376522399e-15 370.241647101317 52.4169598862432 7.06339413626479 5.00908429310811e-12 -270.836768546159 143.240298130742 -1.8907861270922 0.0591859859597714 NHP2 essential 2.77191739049296e-11 1 5.99086481455731e-08 7.06339413626479 -1.8907861270922 1.61748614252793e-29 446.840166154955 54.5999949618555 8.18388658217139 1.97243274651792e-15 -850.361851527538 149.205897733222 -5.69925093073715 1.97758498394232e-08 RMND5B other 2.20220738305177e-25 0.000267666127576593 2.54167683716299e-11 8.18388658217139 -5.69925093073715 2.70381309337479e-11 129.561521091643 30.2780564983285 4.27905671880874 2.2225890993139e-05 -317.884575053093 83.6762727187987 -3.79898105788449 0.000161899877331366 BOD1 other 2.39990450167947e-07 1 0.194809934554863 4.27905671880874 -3.79898105788449 0.336151920187922 137.911508387432 94.0080508900865 1.46701805942852 0.142951128865845 95.3768589367651 262.398871960248 0.363480445720872 0.716387744673224 CPLX2 other 1 1 1 1.46701805942852 0.363480445720872 0.0508440855787354 -16.5916981693232 15.0515643141483 -1.10232383977041 0.270808343970798 -93.6170905612452 38.3990560467389 -2.43800499802119 0.0150876419260487 TENM2 other 1 1 1 -1.10232383977041 -2.43800499802119 0.0203449981194581 -12.5534583411339 20.3952446707083 -0.615509082818861 0.538476933940954 122.856819024611 52.9319415962681 2.32103367682384 0.0206550959283047 KCNMB1 other 1 1 1 -0.615509082818861 2.32103367682384 9.64169270645386e-07 57.0909345584936 11.0836686309871 5.15090593730688 3.65727865887182e-07 11.9179973788964 33.8503240822969 0.352079269608213 0.72491823609198 FAM50B other 0.0064473999128057 1 0.00361817553685305 5.15090593730688 0.352079269608213 0.389524396843711 4.49169075838232 3.30854181431221 1.35760434973256 0.175172510873357 2.29468773224948 10.1896063621059 0.225198859573534 0.821912206352426 MYLK4 other 1 1 1 1.35760434973256 0.225198859573534 3.98933475882816e-23 51.553317582441 8.21765794405494 6.27348058697639 7.28232484363126e-10 -147.970199470667 24.6393933510414 -6.00543192612382 3.52230165057865e-09 FARS2 other 5.00900872318464e-19 4.87345656374061e-05 8.15037796499211e-06 6.27348058697639 -6.00543192612382 0.0667013774335633 42.3362040594825 18.1952250892658 2.3267755057594 0.020348957835009 50.461621059487 61.7590171700777 0.817072929132294 0.414249769441638 GFOD1 other 1 1 1 2.3267755057594 0.817072929132294 2.61876295027586e-10 108.314785972976 16.0285349792196 6.75762233500458 3.70587074858074e-11 68.8036199277904 58.5320153450146 1.1754869454303 0.240327738294891 CDKAL1 other 2.21390219816321e-06 1 4.32104529284514e-07 6.75762233500458 1.1754869454303 0.694851337750282 0.53392576452409 0.855214523070022 0.624317934414187 0.53268247582548 -0.668924956467999 2.08671972577989 -0.320562914225578 0.748665655881175 PCDHB18P other 1 1 1 0.624317934414187 -0.320562914225578 0.181507580889331 0.404501867750026 2.28235323450838 0.177230177009456 0.859393560128638 9.71871580936516 5.43700350336096 1.78751325125272 0.0744111317085732 PSD2 other 1 1 1 0.177230177009456 1.78751325125272 0.662650722295474 -0.589256581735595 1.38382573869901 -0.425817041305777 0.670409894107809 -2.93917918324137 3.26820311849594 -0.899325738540389 0.368877815120553 LRRTM2 other 1 1 1 -0.425817041305777 -0.899325738540389 4.60826222683499e-32 320.359481065385 36.7260041214738 8.72296043985001 3.37622834055467e-17 -561.925846977483 93.1688573968497 -6.03126262012614 3.02334425908871e-09 ZMAT2 essential 6.42852580643481e-28 4.18823880211559e-05 4.48633221892905e-13 8.72296043985001 -6.03126262012614 2.30918339029064e-08 0.794298664381847 11.7178735466486 0.0677852223972003 0.94598155966917 153.765396674583 27.1922432447171 5.65475217659569 2.525496276163e-08 GFRA3 other 0.000174828274478904 0.000340840977430959 1 0.0677852223972003 5.65475217659569 0.00765984155709527 5.2874762157107 10.1867283437428 0.519055386311399 0.603932822399145 -63.8912796999739 23.5544755426552 -2.71249001423411 0.00688899483833171 KLHL3 other 1 1 1 0.519055386311399 -2.71249001423411 0.404149708193604 -11.0263963172583 29.6719164634595 -0.371610520366526 0.710329434163263 -140.049896644997 103.968750664532 -1.34703837210554 0.178536029203719 DCDC2 other 1 1 1 -0.371610520366526 -1.34703837210554 0.377711906440713 -0.901965336517429 2.18239621966753 -0.413291284318132 0.67955758632788 -10.6373373832396 7.61614385533314 -1.39668283389775 0.163083783989348 KAAG1 other 1 1 1 -0.413291284318132 -1.39668283389775 0.00848772157594892 19.9921795220184 8.12016107755164 2.46204223427134 0.0141400620214946 -20.7024763820111 21.4336710280123 -0.965885701751902 0.334552966548122 TRIM7 other 1 1 1 2.46204223427134 -0.965885701751902 1.42686585590426e-30 167.985812869177 22.0684386142144 7.61203888529642 1.28942399208414e-13 -401.352066402111 58.2510185255554 -6.89004375478916 1.62745310344831e-11 TRIM41 other 1.96236861162513e-26 2.35557562193108e-07 1.60159354056771e-09 7.61203888529642 -6.89004375478916 2.02395315873343e-11 149.352120374566 34.6597801598476 4.30909023905427 1.94695498186413e-05 -378.974449427771 97.1298614726374 -3.90172953695124 0.000107522200529974 HIGD2A other 1.80739017074895e-07 1 0.171351507953862 4.30909023905427 -3.90172953695124 1.79150272292224e-08 74.4634917357104 25.6299570190676 2.9053303398173 0.00381960953807886 -291.58892855036 73.1089898541039 -3.98841413528287 7.57192558940946e-05 FAM193B other 0.000136530422513904 0.861079378027643 1 2.9053303398173 -3.98841413528287 1.17733032437951e-11 60.9853883727932 8.52524758612084 7.15350349145024 2.76284252969944e-12 122.011903527782 39.7537333787908 3.0691935865545 0.00225399915827345 PLA2G7 other 1.06289381684982e-07 1 3.32618612150516e-08 7.15350349145024 3.0691935865545 3.8316701773616e-07 333.147023176573 61.5306658955435 5.41432500896601 9.23715351489617e-08 117.283857933822 289.386202424241 0.405284899388133 0.685427146551444 TNFRSF21 other 0.0026522820967697 1 0.00094569977685507 5.41432500896601 0.405284899388133 1.00958853218502e-12 162.286267707942 30.2481203612455 5.3651686706413 1.20009588671594e-07 -274.951459255511 85.2356650862269 -3.225779478313 0.00133207843101607 RNF44 other 9.53859245208406e-09 1 0.00121941743049206 5.3651686706413 -3.225779478313 5.8021638569879e-56 414.374156160995 23.9715341821481 17.2860924550079 1.19889485257602e-53 -69.4335667442945 115.901831005643 -0.59907221604561 0.549375036756312 MUT other 8.86222507516332e-52 1 1.84414006223244e-49 17.2860924550079 -0.59907221604561 6.48244981681654e-11 8.39269321674885 3.1036340170508 2.70415041549388 0.0070667640727434 58.2318282351458 8.3272739860829 6.99290408031089 8.09607180394033e-12 RASGEF1C other 5.64686203542889e-07 1.17708787957488e-07 1 2.70415041549388 6.99290408031089 0.235288065033966 10.696451487346 6.28686569463047 1.70139653157879 0.0894452650623516 11.9139163238837 17.9048367329034 0.665402120198598 0.506077957522914 DOK3 other 1 1 1 1.70139653157879 0.665402120198598 8.02784840353732e-42 177.802740986741 12.6535516221258 14.0516075088229 2.17145923373549e-38 -61.1239053816796 48.4052562288315 -1.26275347232379 0.207228915985467 ABT1 essential 1.18491042436211e-37 1 3.27108618969914e-34 14.0516075088229 -1.26275347232379 1.51267456684543e-05 185.953393182777 39.5375636982252 4.70320818455296 3.25658376248161e-06 310.982584280172 153.221646767464 2.02962564912342 0.0428844355628254 PPP1R18 other 0.0905789530627043 1 0.0303318211637537 4.70320818455296 2.02962564912342 0.203387683765569 -6.0985082366483 21.5526107165263 -0.282959142020416 0.777316191861842 -171.919842971388 96.6337942231827 -1.77908612978941 0.075785984682437 DAAM2 other 1 1 1 -0.282959142020416 -1.77908612978941 2.61377489164541e-23 97.9493778138178 10.3349031370921 9.47753225303834 9.96130816954653e-20 -74.9474820251525 38.8650002082575 -1.92840554801357 0.0543627231677927 PRIM2 other 3.29048121109241e-19 1 1.36579496312652e-15 9.47753225303834 -1.92840554801357 0.713230128137852 7.08294392624077 12.8754703378453 0.550111470912376 0.582477774021228 -18.94267834682 46.2470543927122 -0.409597510491503 0.682268927216382 MLIP other 1 1 1 0.550111470912376 -0.409597510491503 0.12421471471049 -15.6273152823582 8.73524782612717 -1.78899506841887 0.074197537153454 -47.7017771898207 32.4118755040085 -1.47173764085084 0.141696658932119 HMGCLL1 other 1 1 1 -1.78899506841887 -1.47173764085084 0.633790247880198 1.19858615710781 5.83000434190367 0.205589239186815 0.837188834829976 18.5067229631633 19.5102715476542 0.948563064228005 0.343264844911619 FGD2 other 1 1 1 0.205589239186815 0.948563064228005 0.000129763450183994 284.429095185733 69.8581837807969 4.07152147095927 5.3644482796519e-05 36.8238006337139 233.328805850925 0.157819350677348 0.874657712071129 SCUBE3 other 0.695791619886577 1 0.454583347217702 4.07152147095927 0.157819350677348 0.0140163488665287 34.9300036413644 16.0865156238347 2.17138406216509 0.0303320514213455 -33.3626931407468 31.2568587592884 -1.06737191339909 0.286275633288571 ANO7 other 1 1 1 2.17138406216509 -1.06737191339909 0.703474738516481 -0.686082861538748 0.957321585117816 -0.716669165517993 0.473888668911829 -2.9892679545371 5.06334264987041 -0.590374414935874 0.555187095130072 TTBK1 other 1 1 1 -0.716669165517993 -0.590374414935874 1.10487415565242e-71 966.877646439525 48.8410100349684 19.7964302078781 5.48672721009011e-66 -602.391940670906 239.117886333001 -2.51922576729372 0.0120488959192319 RPL7L1 essential 1.7114500671056e-67 1 8.49948912115059e-62 19.7964302078781 -2.51922576729372 1.60818435263326e-06 58.7161393594995 11.8473590260977 4.95605300980228 9.70576410430009e-07 -32.5015909970872 62.7621278992159 -0.517853554125485 0.604777354476737 NFKBIE other 0.0105384320628058 1 0.0093437391032097 4.95605300980228 -0.517853554125485 1.04090555949071e-68 250.17404499322 12.1285514180842 20.6268693077558 8.97836050629145e-70 228.572430902907 56.2597522410271 4.06280550123401 5.58538693131331e-05 CYP39A1 other 1.60944817608454e-64 0.641928520015839 1.39317219976124e-65 20.6268693077558 4.06280550123401 2.46781833572289e-08 -139.642713396915 87.228375127233 -1.60088633077515 0.109994597484371 -1104.37464631466 191.388815667343 -5.77031966295354 1.34319740429221e-08 TPBG other 0.000186468353447222 0.000182983782386728 1 -1.60088633077515 -5.77031966295354 2.81134925772476e-13 9.8092104655859 8.40166424747758 1.16753183377102 0.243518665030983 -106.668688947257 17.8773148272636 -5.96670640853645 4.42140015303532e-09 IRAK1BP1 other 2.71829359729407e-09 6.10241649121934e-05 1 1.16753183377102 -5.96670640853645 7.54244634858209e-14 124.191777100369 65.9671760681168 1.88262988508301 0.060295988059603 -790.75336086987 140.366948749388 -5.63347260815426 2.8653341569343e-08 PHIP other 7.45467554436914e-10 0.000386067863577934 1 1.88262988508301 -5.63347260815426 2.01635277012855e-23 160.158907250585 18.8917817388675 8.47770260446516 2.22782417350318e-16 -46.5813980195863 42.9919289263262 -1.08349169676502 0.279076472461506 MMS22L other 2.5426208431321e-19 1 2.91889523212387e-12 8.47770260446516 -1.08349169676502 3.50586050641556e-13 68.263615229955 12.9238565893118 5.28198489036237 1.86362705262384e-07 -60.938043291015 29.5617848522829 -2.06137902685903 0.0397503830630166 FAXC other 3.37439073742497e-09 1 0.0018742497268238 5.28198489036237 -2.06137902685903 4.19874848521268e-13 218.152817861629 61.7199029513525 3.53456190677385 0.000443300444316307 -531.700048972116 138.260075092489 -3.84565138284814 0.000134488010491017 PNRC1 other 4.02198117398523e-09 1 1 3.53456190677385 -3.84565138284814 6.60413984708592e-10 164.7336185296 29.9190519553803 5.5059772206444 5.67530996203722e-08 -5.89924510321304 67.0121206224498 -0.0880325088717866 0.929883353768921 PM20D2 other 5.45634034166239e-06 1 0.000587905358967435 5.5059772206444 -0.0880325088717866 1.46252072631249e-52 134.930025805149 17.5049353893673 7.70811332940463 6.13704459791544e-14 -330.985997678093 38.5098377419671 -8.59484269697124 8.94532815154008e-17 RARS2 essential 2.22215399155919e-48 1.35897425278197e-12 7.68173872321075e-10 7.70811332940463 -8.59484269697124 0.590678900605105 -1.43993695300372 1.44374603924861 -0.99736166462706 0.31904670960261 -2.72793740927332 4.14542641858552 -0.658059541726018 0.510787221246736 SCML4 other 1 1 1 -0.99736166462706 -0.658059541726018 4.62942942194712e-32 39.1601609598634 3.85060998360324 10.1698590941737 2.52825167670947e-22 -40.9042818573415 11.7509059404859 -3.48094709161207 0.000540610200202674 TBC1D32 other 6.45759110067403e-28 1 3.54814840309406e-18 10.1698590941737 -3.48094709161207 0.506777312726006 -9.21227832620677 8.98429866426112 -1.02537534319207 0.305651243520644 -20.0509458123154 20.5341920974127 -0.976466262572939 0.32927642741703 CLVS2 other 1 1 1 -1.02537534319207 -0.976466262572939 3.09852471214229e-07 45.9490610872403 16.4176261768045 2.79876399866864 0.00531459510279141 -108.600011204127 37.263104829038 -2.91441123069001 0.00371248646904587 RNF217 other 0.00215936187189196 1 1 2.79876399866864 -2.91441123069001 0.519238514182506 -4.47955528053363 9.67236394303896 -0.463129314293172 0.643458961349022 -25.7712507577958 22.5382616854354 -1.14344447311346 0.253362630291021 RSPO3 other 1 1 1 -0.463129314293172 -1.14344447311346 2.80706577044302e-07 38.2685119627549 25.9949792028754 1.4721501280725 0.14156075023002 -255.419169258815 61.6729513849504 -4.14151039512507 4.00129655727615e-05 ARHGAP18 other 0.00196270038669376 0.464270439540752 1 1.4721501280725 -4.14151039512507 1.37358454856728e-23 420.822866745309 44.0634676238573 9.55038015477164 4.89714472166709e-20 -4.42946950875588 99.6428106247443 -0.0444534781885801 0.964559836818839 ABRACL other 1.7373097370279e-19 1 6.73847113701391e-16 9.55038015477164 -0.0444534781885801 2.57440924647131e-06 30.006951918406 15.8292062257722 1.8956700348973 0.0585383441770176 -125.195113431889 37.4260346108695 -3.34513433585959 0.000879678096574305 SLC18B1 other 0.0165483026363176 1 1 1.8956700348973 -3.34513433585959 2.02219341826109e-25 51.2548164837125 5.04420532783489 10.1611280970024 2.78800913665506e-22 4.75610550200437 11.6750434695891 0.407373686821208 0.683898034266722 MTFR2 other 2.62804256637211e-21 1 3.91046161507239e-18 10.1611280970024 0.407373686821208 0.0108829208143689 42.8834056228715 14.4402882057804 2.9697056604248 0.00311535939804445 29.8106205214766 33.0962237761235 0.900725736057622 0.368141720905156 SLC2A12 other 1 1 1 2.9697056604248 0.900725736057622 3.84456141002277e-13 52.584559884137 15.2831227709518 3.44069472399208 0.000625114613719983 -152.483105225687 33.6284903962145 -4.53434285717602 7.12307520101865e-06 SHPRH other 3.69077895362186e-09 0.0867875482492113 1 3.44069472399208 -4.53434285717602 5.1298323433356e-11 99.0732338236465 37.056530509468 2.67357014975628 0.0077358881624245 -355.999557931823 80.9585204186386 -4.39730810408762 1.32459702342922e-05 AIG1 other 4.48962926688731e-07 0.158805937138929 1 2.67357014975628 -4.39730810408762 8.02550713362695e-42 529.748349478226 53.8535224552519 9.83683750526078 4.07097267837943e-21 -588.001285251163 114.001994006434 -5.15781579415163 3.51145234203429e-07 DYNLT1 other 1.18464510799467e-37 0.00454417047582658 5.6553952448047e-17 9.83683750526078 -5.15781579415163 1.48922254594208e-19 71.6385918274238 14.313417785832 5.00499551535027 7.56387283814446e-07 -142.515109760111 30.0436329362433 -4.74360441237408 2.68846593892541e-06 TIAM2 other 1.74775157991763e-15 0.033482154803377 0.00733468749114868 5.00499551535027 -4.74360441237408 0.000385145861133544 102.655863578622 124.788354491806 0.822639772731063 0.411075311409256 -795.845754464437 264.163244895788 -3.01270434037254 0.00271047255302462 TMEM181 other 1 1 1 0.822639772731063 -3.01270434037254 0.745972891771713 0.18844713758796 8.06108530993108 0.02337739030696 0.981357765262916 11.6702172682468 16.9826791081937 0.687183523512273 0.49225832412786 PNLDC1 other 1 1 1 0.02337739030696 0.687183523512273 7.91803065298797e-32 281.236447507499 38.5715427700922 7.29129371837224 1.08427518328751e-12 -474.74500074771 81.3387051599516 -5.83664320466043 9.14131459017822e-09 WTAP essential 1.10179396536328e-27 0.00012513545542495 1.31652692754769e-08 7.29129371837224 -5.83664320466043 7.88179775839494e-11 205.678196063443 68.2710251319348 3.01267185699888 0.0027112129335708 -582.012361013798 129.263801896019 -4.50251619151644 8.2358864675118e-06 ZMYM4 other 6.83824773518345e-07 0.0999754258291258 1 3.01267185699888 -4.50251619151644 0.0906817632075631 500.254801470741 269.329460089886 1.85740839974872 0.0637922624526717 -124.006101534753 587.985133707255 -0.21090006264766 0.833044086481038 ARMT1 other 1 1 1 1.85740839974872 -0.21090006264766 0.0943712162812508 10.5464248355584 7.82505240348484 1.34777689550828 0.17828909039529 35.2413914025027 16.4505536414733 2.14226172386417 0.0326140510421616 SLC22A3 other 1 1 1 1.34777689550828 2.14226172386417 0.464036585074702 7.34271410918537 5.9456565327339 1.23497112030605 0.21737535816155 4.22905484617093 21.4086089662782 0.197539917368398 0.843478970886121 VWDE other 1 1 1 1.23497112030605 0.197539917368398 3.69323379973917e-05 168.956045270843 45.9815004944726 3.67443522838394 0.000262151855207218 -268.558049303927 161.644317480108 -1.66141348790053 0.0972108370354805 GNA12 other 0.21225014647101 1 1 3.67443522838394 -1.66141348790053 3.70866478039605e-10 308.13709634619 58.5851924353592 5.25964127686663 2.11556372460617e-07 -568.889297173157 212.113344435388 -2.68200616367372 0.00755183497580673 C7orf50 other 3.10823195244993e-06 1 0.00212233352852491 5.25964127686663 -2.68200616367372 0.571113375234019 13.7904520268606 20.8799206807803 0.660464770805117 0.509236214601285 -45.1903671047317 72.0178156430549 -0.627488722078308 0.530603184660776 SDK1 other 1 1 1 0.660464770805117 -0.627488722078308 0.789423951429969 11.1859092230718 16.2979063611212 0.686340255933476 0.492790993013023 8.58528559329923 43.5113641483715 0.197311340642501 0.843657604563398 WASH2P other 1 1 1 0.686340255933476 0.197311340642501 1.44028265753577e-19 193.154217215482 21.4100576072799 9.02165798702963 3.15711799835765e-18 -79.4351322601427 76.4848737350574 -1.03857309793444 0.29946386779626 CCZ1B other 1.6911798964785e-15 1 4.25453221458677e-14 9.02165798702963 -1.03857309793444 5.27914078434829e-14 68.7390952652814 12.7250970231849 5.40185235051961 9.87513918732764e-08 -191.36744955208 44.7956527958709 -4.27200939394994 2.28678242075075e-05 C7orf26 essential 5.24641011148533e-10 0.269794590000174 0.00100874546798552 5.40185235051961 -4.27200939394994 2.54253189498139e-07 57.9716731163343 16.0510843724735 3.61169823614855 0.000332359309071618 -177.5309805993 55.2287389701716 -3.21446739341962 0.00138436685091504 RBAK other 0.00178485739027694 1 1 3.61169823614855 -3.21446739341962 0.0560848163851888 5.81515208774107 12.2179373803623 0.475952029111531 0.634301404216557 118.991889849139 49.4401442546745 2.40678686607773 0.0164288855827576 CREB5 other 1 1 1 0.475952029111531 2.40678686607773 0.450469464536528 119.030286424454 104.080203768342 1.14364002101098 0.253288264013632 333.019521718893 443.957685250022 0.750115456456954 0.45351739851035 EGFR og 1 1 1 1.14364002101098 0.750115456456954 5.15730402871198e-07 220.649596784567 43.4745205584927 5.07537734631701 5.38364699727065e-07 10.5586353926858 104.928423938129 0.100627027419298 0.919885103299169 CDCA5 essential 0.00352604876443038 1 0.00526682185742988 5.07537734631701 0.100627027419298 0.927696138295754 -58.1270581527129 185.095948014144 -0.314037442614742 0.753613211814372 -210.06840184953 741.974630790297 -0.283120733691098 0.777192189625543 IGFBP3 other 1 1 1 -0.314037442614742 -0.283120733691098 0.763489495408334 -16.0189977973568 24.3023771173317 -0.65915353547586 0.510076608844391 -43.3282231577298 97.2740131791278 -0.445424443195757 0.656190574792259 IGFBP1 other 1 1 1 -0.65915353547586 -0.445424443195757 0.000887378330133522 11.6285904029389 4.53115270936832 2.56636470867475 0.0105465597266499 -32.6245562013682 15.4361365996823 -2.11351823629494 0.0350161497122424 SSC4D other 1 1 1 2.56636470867475 -2.11351823629494 2.84666624976453e-18 984.317706557293 122.70676586828 8.02170686833936 6.6462291883876e-15 -1213.88036712589 428.745436849767 -2.83123798598288 0.00481165274445001 MDH2 other 3.23466685960744e-14 1 8.48457618189562e-11 8.02170686833936 -2.83123798598288 2.04094719480556e-10 48.6103946815314 12.2732673470133 3.96067268047908 8.47759003367825e-05 -189.107435217522 41.8986331959733 -4.51345117471986 7.83698438617242e-06 POMZP3 other 1.73807063109641e-06 0.0952507082295395 0.705420266702368 3.96067268047908 -4.51345117471986 8.04872561987574e-11 247.587216601939 47.9526222704655 5.16316324069791 3.4517736655222e-07 -756.581045321583 207.663495697904 -3.64330304071453 0.000295898496209263 NIPSNAP2 other 6.97904998499425e-07 1 0.0034213980572656 5.16316324069791 -3.64330304071453 8.83758333243593e-09 696.129257205557 112.460544454221 6.18998654669439 1.21369005810089e-09 398.855215575893 487.021328212892 0.81896868262316 0.413175875701155 CCT6A essential 6.85708090763704e-05 1 1.34683185747455e-05 6.18998654669439 0.81896868262316 3.11747303752498e-10 99.1527915848271 15.6984031845129 6.3161068307027 5.72263108466773e-10 -80.5098184709424 67.9834621719722 -1.18425593370463 0.236847636892963 PSPH other 2.62428880298853e-06 1 6.43223733916653e-06 6.3161068307027 -1.18425593370463 0.0920288034165023 -78.8866870865723 60.8581239840957 -1.2962392187309 0.19546917378057 -491.912435729888 245.898415213475 -2.0004701343961 0.0459699683855802 ZNF92 other 1 1 1 -1.2962392187309 -2.0004701343961 5.82257311995314e-06 10.1655204152071 7.02560757879653 1.44692402773632 0.148497356812608 -88.1677703065482 21.5501553433104 -4.09128235513705 4.94344727256543e-05 ATXN7L1 other 0.0361057759168294 0.570671553144953 1 1.44692402773632 -4.09128235513705 9.10046950384392e-11 27.7203875232579 20.2150697224572 1.37127340661422 0.170862483258974 -379.068860576757 62.5385749461385 -6.06136070262604 2.54408494147641e-09 TMEM168 other 7.86462574522192e-07 3.5319531242517e-05 1 1.37127340661422 -6.06136070262604 1.19706308093573e-16 111.547276671386 25.0637301541215 4.45054570829883 1.03984350040045e-05 -478.491574251457 79.3348851143953 -6.0312884245248 3.00969706740763e-09 SLC12A9 other 1.30156668790142e-12 4.16963431718654e-05 0.0936171103410526 4.45054570829883 -6.0312884245248 3.41898381384242e-11 113.139443790308 50.8190228124715 2.22632072654774 0.0264045190214423 -949.952788150196 163.596915597282 -5.80666685971419 1.0884656594807e-08 GIGYF1 other 3.0203303011484e-07 0.000148553793205926 1 2.22632072654774 -5.80666685971419 8.90506083587674e-08 31.9361227966907 29.4162962419496 1.08566090489487 0.278115256756614 -485.611568630027 93.8967194063639 -5.17176288692696 3.27669933207671e-07 TRIM4 other 0.000646062163642858 0.00424365330497254 1 1.08566090489487 -5.17176288692696 5.76451962527473e-19 177.521261410158 35.7928781843381 4.95968109901361 9.46758557091086e-07 -731.214312803997 114.711279845724 -6.37438893356795 3.93812427466119e-10 MEPCE essential 6.65629081130473e-15 5.56693247466106e-06 0.00912296545612971 4.95968109901361 -6.37438893356795 2.43690995351426e-19 170.070923882856 25.1957237265327 6.74999161479775 3.80534402038064e-11 -356.750226023068 82.5523939521697 -4.32150067301217 1.84346104165697e-05 TMEM209 other 2.84631082570465e-15 0.219021606359265 4.43512845575364e-07 6.74999161479775 -4.32150067301217 0.0175905635438286 3.67108723386949 1.52390573064167 2.40899890331386 0.0163258205458245 -3.25821017113943 4.96151708709387 -0.656696351931315 0.51165235552122 AGBL3 other 1 1 1 2.40899890331386 -0.656696351931315 2.98472215876812e-05 11.8930574555646 3.78203405543525 3.14461934536862 0.00175349580239036 -23.8280996408239 11.1797403011488 -2.13136432501705 0.0335050931831129 ZC3HAV1L other 0.173173579651726 1 1 3.14461934536862 -2.13136432501705 2.66122191770143e-06 68.4855234244222 17.1226654697966 3.99969990333728 7.21445139563687e-05 -96.0283597719146 55.7478035529248 -1.72254965490701 0.0855352214652601 TMEM140 other 0.0170903671554786 1 0.603849581814806 3.99969990333728 -1.72254965490701 2.08755672666869e-80 214.201674875061 9.3197084456398 22.9837313178262 8.3754851298111e-81 38.3227973826636 35.8848412723574 1.06793832782491 0.286052578818836 TLK2 other 3.24740324400582e-76 1 1.30481682837327e-76 22.9837313178262 1.06793832782491 2.56075051802762e-15 82.9201477844509 15.9028251673016 5.21417716110885 2.6291247505792e-07 -238.44918803471 51.8827243740381 -4.5959265036982 5.36304764384575e-06 EPHA1 other 2.67009456514739e-11 0.0658045945899873 0.00262228902622769 5.21417716110885 -4.5959265036982 5.08064634616779e-25 115.406510741456 13.1357340822047 8.78569176410176 2.08394471231343e-17 -134.302312762987 38.4526133215446 -3.49267061876751 0.000517557017692142 NOM1 essential 6.56521120851802e-21 1 2.77664793468641e-13 8.78569176410176 -3.49267061876751 2.18077456233753e-06 193.002323328414 40.355476330741 4.78255594721832 2.24410763394315e-06 -35.559342176367 119.334598242004 -0.297980155799029 0.76583464437281 NCAPG2 essential 0.0141248768402602 1 0.0211507144499142 4.78255594721832 -0.297980155799029 0.000213637346606126 -0.743265146266703 1.37855338478009 -0.539163121626422 0.5899948878717 -18.2964048565404 4.49812496816908 -4.06756259241676 5.45362387674984e-05 RAB19 other 1 0.627657571975139 1 -0.539163121626422 -4.06756259241676 1.4396532277019e-16 168.121060888142 45.8729017672435 3.66493189685665 0.000271601847146288 -870.844412043823 136.864207745411 -6.36283529776999 4.20157353062414e-10 LUC7L2 other 1.56101599479717e-12 5.9347226120066e-06 1 3.66493189685665 -6.36283529776999 0.00308896056985702 23.1574490261999 9.4085113330523 2.4613297690196 0.014151619299503 -45.4462992905141 30.8851478142564 -1.4714612850108 0.14174463090095 DENND2A other 1 1 1 2.4613297690196 -1.4714612850108 6.55316578562272e-70 95.2031677174985 10.3023296340349 9.24093589502164 5.80499904783887e-19 -215.366106747312 22.5033352247122 -9.57040832377622 3.95240867144229e-20 MCPH1 other 1.01403687366726e-65 6.089080799224e-16 7.89189620553694e-15 9.24093589502164 -9.57040832377622 1.63518390823695e-05 88.6754539225493 29.1808909778475 3.03881927353989 0.00249135724752513 -58.2847343439776 60.7049124449581 -0.960132088104486 0.337423265326797 MFHAS1 other 0.097571423804499 1 1 3.03881927353989 -0.960132088104486 4.10106026460273e-45 249.791333362467 29.7561205741384 8.39462028459333 4.79816065359403e-16 -315.688443234622 61.3029664377505 -5.14964383583599 3.75465114930359e-07 FBXO25 other 6.12616382326356e-41 0.00485288661047489 6.24816480311014e-12 8.39462028459333 -5.14964383583599 7.17371048734587e-08 49.5130182110136 24.8671395752406 1.99110227620679 0.0469702906592444 -154.6195665706 50.8834395217385 -3.03870115746683 0.00249036503038847 CSGALNACT1 other 0.000524398236624983 1 1 1.99110227620679 -3.03870115746683 2.29107329678224e-08 256.603597014386 124.414530066137 2.06248897840131 0.039635382641077 -785.166237313571 253.796566695586 -3.0936834470867 0.00207842256312352 ATP6V1B2 essential 0.000173525891498287 1 1 2.06248897840131 -3.0936834470867 4.4015929386313e-92 230.951683381589 20.3140637606796 11.3690537798067 5.26146816582428e-27 -465.960683646252 43.1484639679532 -10.7990097629507 9.44009839415546e-25 CCDC25 other 6.86648498426483e-88 1.46925691406636e-20 7.6233412254628e-23 11.3690537798067 -10.7990097629507 1.01458537727549e-39 56.8937482849331 12.7936562919691 4.44702804159644 1.05713843234559e-05 -205.403737747789 25.7858055909344 -7.96576771756953 9.75503447582943e-15 HMBOX1 other 1.48433840695404e-35 1.46130416447925e-10 0.0950684592208388 4.44702804159644 -7.96576771756953 0.0150057912831132 -2.44116248693833 1.15434120256962 -2.11476683107575 0.0350724595411637 -13.2233385579937 5.10981359730299 -2.58783188587802 0.0100125056362009 CHRNA6 other 1 1 1 -2.11476683107575 -2.58783188587802 3.52263845044537e-09 2.88779533023193 1.73972465832841 1.65991515749776 0.0975067529342509 -12.5838205333455 3.49052748571618 -3.60513434855923 0.000340616663059806 GNRH1 other 2.80190662348424e-05 1 1 1.65991515749776 -3.60513434855923 3.43770656459006e-49 98.6657243057689 15.7007014531607 6.28416027144485 6.87592088524957e-10 -254.088268611771 31.8552768116436 -7.97633215100167 9.32379941003211e-15 BIN3 other 5.18646789399702e-45 1.39717134159331e-10 7.70103139147952e-06 6.28416027144485 -7.97633215100167 0.986656613080203 -1.35037838203214 8.30400459499085 -0.162617730588289 0.870879923577167 -1.98856228889896 16.7999457376325 -0.118367185225159 0.90582049878128 DOK2 other 1 1 1 -0.162617730588289 -0.118367185225159 1.8041669324088e-07 -38.9929527525304 83.0791531006079 -0.469347017841052 0.639009321474154 -775.483463923608 168.398357952186 -4.60505359644773 5.13753272826881e-06 SLC25A37 other 0.00128131935539673 0.0631043145013258 1 -0.469347017841052 -4.60505359644773 8.55899710568872e-66 260.464934161337 30.6039911177787 8.51081589845405 1.67962264200825e-16 -517.394134718338 61.9784771012364 -8.34796463090276 5.75201538206053e-16 CHMP7 essential 1.32168033306045e-61 8.69647205613732e-12 2.20484064216424e-12 8.51081589845405 -8.34796463090276 5.26904272553705e-13 24.5705229050907 40.7026482011834 0.603659073572915 0.546321490285477 -447.595750025442 81.6644815646728 -5.48091093520231 6.47759406367372e-08 DOCK5 other 5.0271936644349e-09 0.000862491649578156 1 0.603659073572915 -5.48091093520231 7.66816802155363e-124 420.702066328832 13.2608019457011 31.7252356268857 2.28959528037298e-117 -211.439826763701 84.8330241915705 -2.49242354352741 0.0130421729600268 PLPBP other 1.20014497705336e-119 1 3.58207181614353e-113 31.7252356268857 -2.49242354352741 1.36191511539868e-69 1224.55758584938 59.579737199291 20.5532559123802 6.430057156182e-67 -81.6832263150096 350.523371524352 -0.23303218258967 0.815840979175858 ERLIN2 other 2.10674649201022e-65 1 9.96530258065086e-63 20.5532559123802 -0.23303218258967 0.032478683789277 92.6163220608818 35.7218544637828 2.59270755819193 0.00981594563515584 -17.8048233571086 289.83177537342 -0.0614315781427649 0.951041343355796 PXDNL other 1 1 1 2.59270755819193 -0.0614315781427649 0.000416615357042607 69.9436388155562 23.9490328166746 2.92052039641691 0.00366967749893732 -665.434251434036 298.489986692563 -2.22933525780018 0.0262833722674681 TACC1 other 1 1 1 2.92052039641691 -2.22933525780018 2.02855794345828e-60 354.867891199737 20.564900752201 17.2559982406799 7.56347167918319e-51 -268.458550019607 88.5488025835636 -3.03175810611626 0.0025815410736218 GOLGA7 other 3.1189078380671e-56 1 1.16008528615312e-46 17.2559982406799 -3.03175810611626 4.9791989019588e-101 484.842623445277 17.97167367842 26.9781564099656 6.44874040682991e-96 -224.997083107021 113.740034773779 -1.97816963529618 0.0485217862098862 PLPP5 other 7.77701076496946e-97 1 1.00729325154683e-91 26.9781564099656 -1.97816963529618 2.5819819697308e-19 83.713260296528 9.26157044098439 9.03877596461171 5.86429635075862e-18 -13.180515961941 40.3031412672181 -0.327034458047611 0.743804748145797 GINS4 essential 3.01291476047887e-15 1 7.88220072505466e-14 9.03877596461171 -0.327034458047611 1.0386305174203e-33 332.061542403975 27.2754667618769 12.1743669981149 1.17878688724643e-29 -1312.14463355591 342.448646207884 -3.8316537328618 0.000145461626488699 NSD3 other 1.4678965102701e-29 1 1.73022339310031e-25 12.1743669981149 -3.8316537328618 4.00891228464306e-07 4.01638593251589 0.740051660313054 5.42716968004219 8.76630619089754e-08 10.3255214300628 6.77979296812875 1.52298476938782 0.128365757073813 DNAJC5B other 0.00276872714309708 1 0.000898721710690816 5.42716968004219 1.52298476938782 0.771918056298611 2.27268407171332 5.38856553694707 0.421760495651489 0.673373143186309 -25.794464249082 48.6113362064429 -0.530626521754883 0.595902847456232 TRIM55 other 1 1 1 0.421760495651489 -0.530626521754883 1.20956287551612e-33 50.1515206853896 3.95560975784813 12.6785814970464 2.48720787598094e-32 -88.9328716244506 36.1938019115724 -2.45712986554241 0.0143269579657198 ADHFE1 other 1.70790278022876e-29 1 3.68653951377895e-28 12.6785814970464 -2.45712986554241 1.23617661975242e-46 134.114279510485 8.51194949547599 15.7560003829634 5.77604603910105e-46 -196.245391136435 85.6659933204615 -2.29082023717761 0.0223753551924646 MRPS28 other 1.85302875300888e-42 1 8.81135823264866e-42 15.7560003829634 -2.29082023717761 7.13398568432136e-57 92.762352824033 5.08999409245153 18.2244519618598 5.94095534782614e-58 37.8261559657506 47.2983449730887 0.799735297023024 0.42422313881967 LACTB2 other 1.09157114955801e-52 1 9.17105277043921e-54 18.2244519618598 0.799735297023024 4.73039915608117e-52 123.730197172868 7.28489655019811 16.9844823904196 7.56224057516993e-52 -119.652148759978 70.9039860313137 -1.68752358586915 0.092098946416392 TERF1 other 7.1797998391e-48 1 1.16110641791159e-47 16.9844823904196 -1.68752358586915 2.02128386456471e-22 744.136049962042 71.6119853271029 10.3912221754926 4.07512148850094e-23 -363.63476322767 690.165426485179 -0.526880584383313 0.598500340587036 RPL7 essential 2.50982817463e-18 1 5.75977671184723e-19 10.3912221754926 -0.526880584383313 0.0251094085784997 1.81779170434714 1.46411086363025 1.24156698068611 0.214953960510863 37.8242775432149 15.1071620521901 2.50373150248503 0.0125932582907167 SLC26A7 other 1 1 1 1.24156698068611 2.50373150248503 0.73188995282297 -4.25750444387853 7.20331630719559 -0.591047826072221 0.554745191787966 -40.9834663710805 77.8894918577958 -0.526174524875637 0.598991287822012 ATP6V0D2 other 1 1 1 -0.591047826072221 -0.526174524875637 0.0135171162668931 24.9678132250531 27.4324469596354 0.910156256268034 0.363150740106665 -876.351674215631 314.060351570404 -2.79039257847604 0.00545264165607096 SYBU other 1 1 1 0.910156256268034 -2.79039257847604 2.16897604189753e-59 1116.23931920078 59.5438971771723 18.7464941348972 1.48673998507836e-60 19.3079604727116 670.744307763476 0.0287858730208116 0.977046183298581 MTDH other 3.32916132670852e-55 1 2.29805399493562e-56 18.7464941348972 0.0287858730208116 6.50820940749917e-10 47.978065014577 8.62023131115464 5.56575146104178 4.14350421805833e-08 352.670400407337 97.4534862513554 3.61885873941664 0.000324150863108099 LRP12 other 5.37968589623881e-06 1 0.000431836009606039 5.56575146104178 3.61885873941664 7.51695963860608e-59 163.951710306847 8.81388049403854 18.6015354324057 6.17426987290685e-60 -92.9564210426491 101.164422135965 -0.918864745925356 0.358580398864545 EBAG9 other 1.15332711735133e-54 1 9.53986438062837e-56 18.6015354324057 -0.918864745925356 2.82236885441358e-77 343.835776985862 15.4167648122753 22.302719226286 3.00849592181996e-78 -150.087005006779 205.762068817967 -0.729420178699494 0.466066298292725 POLR2K other 4.38426777844605e-73 1 4.68242305272059e-74 22.302719226286 -0.729420178699494 7.61792265821469e-35 1809.96093541386 134.846761320244 13.4223537717412 1.56060818492881e-35 -2253.47251946285 1562.94613034787 -1.44181074171846 0.149950872119792 MAL2 other 1.08540162034243e-30 1 2.33513802710897e-31 13.4223537717412 -1.44181074171846 2.39954383871237e-13 1634.57095602489 209.572632011903 7.7995439592134 3.48686508043703e-14 -1825.31749282094 2488.53712459025 -0.733490159654133 0.463593935509445 EIF3H essential 2.32659770601552e-09 1 4.38961444976218e-10 7.7995439592134 -0.733490159654133 9.18290418399871e-57 283.647885400398 15.5234702126799 18.2721956826836 6.87495330823073e-58 -180.038588431966 181.300710968449 -0.993038513033176 0.321156621455773 UTP23 essential 1.40489251110996e-52 1 1.0612177926585e-53 18.2721956826836 -0.993038513033176 2.29342524783972e-56 970.022279849177 53.4645207580573 18.1432895328626 1.33575737633938e-57 -1.05560752524104 605.068837608108 -0.00174460732338151 0.998608660669488 NDUFB9 other 3.50618851889736e-52 1 2.06147435890457e-53 18.1432895328626 -0.00174460732338151 0.0118636766297741 46.6600410292114 16.1872691936757 2.88251467686973 0.00410372778916813 157.443393831887 180.915312783414 0.87026018643526 0.384548527520705 FAM83A other 1 1 1 2.88251467686973 0.87026018643526 0.000231636418954803 15.7509953461358 4.35212181275863 3.61915314501547 0.000324011523525411 101.386996478822 45.3627402752752 2.23502803983125 0.0258329442913586 GSDMC other 1 1 1 3.61915314501547 2.23502803983125 0.144070777247597 12.3049535814361 8.53129102570769 1.44233194534767 0.149786349305674 -79.5417622220335 67.1868055329793 -1.18388962819478 0.23697570425179 FAM135B other 1 1 1 1.44233194534767 -1.18388962819478 5.916731299586e-53 149.528891501166 8.58966789599186 17.4079945012705 5.69901457791608e-53 -29.7253674090508 58.2786862718132 -0.510055550504535 0.610246992835783 ZNF7 other 8.99698161415047e-49 1 8.76052520917259e-49 17.4079945012705 -0.510055550504535 3.5312921248507e-22 118.767912286752 11.7285735210154 10.1263731752154 5.32524070228639e-22 -102.465941237354 79.1037615409303 -1.29533588847523 0.195818063677645 ARHGAP39 other 4.36503019552795e-18 1 7.45054426656889e-18 10.1263731752154 -1.29533588847523 5.59113798601221e-13 126.68695840505 16.3895574501912 7.72973637574164 6.03765678235422e-14 104.024322036689 111.972569899318 0.929016116449087 0.353332621140189 SLC39A4 other 5.33003184206544e-09 1 7.55793876015101e-10 7.72973637574164 0.929016116449087 8.2920991811122e-05 134.96571936551 33.5755605199155 4.01976072105942 6.71080103282961e-05 -286.358733950932 229.056311520864 -1.25016740228461 0.211815118371638 NAPRT other 0.455733770993926 1 0.563640178747359 4.01976072105942 -1.25016740228461 8.3327451250841e-11 267.751651859427 39.5469440962713 6.7704764041344 3.36263398966293e-11 118.082309737471 93.9135808627226 1.25735073301141 0.209171180951976 VLDLR other 7.21699055283534e-07 1 3.92654770972941e-07 6.7704764041344 1.25735073301141 2.48135549339863e-19 137.614039663362 33.3342876789149 4.12830299506918 4.23067432196659e-05 -526.131421513669 81.3894809281532 -6.46436634702355 2.2708619142777e-10 AK3 other 2.8969825385429e-15 3.22553226304004e-06 0.361807268014583 4.12830299506918 -6.46436634702355 2.57641609867766e-37 289.879246108181 22.6648759940645 12.7898006670804 6.31636228499285e-33 -51.7442743202999 55.6930087738272 -0.929098202082 0.353251025398162 UHRF2 other 3.72524003707803e-33 1 9.37979799321438e-29 12.7898006670804 -0.929098202082 1.93747049102078e-12 1415.39982167216 192.699851696924 7.34510073156821 7.68193817897811e-13 509.90103043954 447.440066820931 1.1395962683056 0.254962600213106 NFIB other 1.81075992090803e-08 1 9.35736889581323e-09 7.34510073156821 1.1395962683056 8.53478509086673e-11 562.962789202887 81.0926776384221 6.94221482873014 1.12411104271805e-11 411.807554786914 186.389102616372 2.209397164353 0.0275706629406553 PLIN2 other 7.38514953912698e-07 1 1.33184676341235e-07 6.94221482873014 2.209397164353 2.60559185838592e-28 229.786562099756 21.0610941470366 10.9104759940541 3.70588583805143e-25 -17.9931708312705 48.2577313771908 -0.372855712810715 0.709403783113565 HAUS6 other 3.50764775975912e-24 1 5.31386970318195e-21 10.9104759940541 -0.372855712810715 0.199937288243676 49.2625112092726 49.431087603775 0.996589668512785 0.319428131675666 -115.685716924001 113.352765620745 -1.02058133553672 0.307928322750095 CDKN2B other 1 1 1 0.996589668512785 -1.02058133553672 7.14870802020896e-17 556.745140295705 62.4756377201949 8.91139587544763 8.50026228877108e-18 379.255044292669 144.314111265895 2.62798309164585 0.00884307548681275 CDKN2A ts 7.82211631571264e-13 1 1.1398851729242e-13 8.91139587544763 2.62798309164585 5.57283089427238e-10 43.3277464237154 9.70764449591798 4.46326052029764 9.87767299843676e-06 -67.341919406926 23.1365251194718 -2.91063239009261 0.00375954798206279 C9orf72 other 4.6299079069615e-06 1 0.0890768550999027 4.46326052029764 -2.91063239009261 1.42138383641219e-26 122.881096871759 15.1558750627292 8.10781933495503 3.53397870636817e-15 -189.861951783475 37.4415656847898 -5.07088708260415 5.46678940231844e-07 ZCCHC7 other 1.8759423872968e-22 0.00702373102409874 4.53268108878782e-11 8.10781933495503 -5.07088708260415 7.1786313920075e-35 138.814953905508 10.8742832284584 12.7654348327276 8.85486791882799e-33 -0.567621122454064 26.8858881546987 -0.0211122325283817 0.983163969077031 FBXO10 other 1.02309854598891e-30 1 1.31432804519164e-28 12.7654348327276 -0.0211122325283817 1.18870151050179e-16 308.703435421458 42.2330242150929 7.30952710961997 9.82204523010511e-13 -289.801218129044 113.103501666225 -2.56226565808956 0.0106718374404789 SIGMAR1 other 1.29283176282174e-12 1 1.19337849545777e-08 7.30952710961997 -2.56226565808956 2.13118701933068e-09 118.505478251885 24.2788824319469 4.88101042476123 1.39095816176434e-06 -128.277953339719 53.4849532636428 -2.39839329591259 0.0168048298465864 CEP78 other 1.7168842627728e-05 1 0.013262786072423 4.88101042476123 -2.39839329591259 0.139850662402333 -345.509612044926 290.385623870046 -1.18983029338791 0.234635957153028 -1202.41531654698 638.530032892638 -1.88309907851923 0.0602241716513633 NTRK2 other 1 1 1 -1.18983029338791 -1.88309907851923 1.17437197505888e-08 6.4814824788271 6.49739346574871 0.99755117386603 0.318946330854768 -79.2135826506609 14.4527140046554 -5.48087941303933 6.51846386085747e-08 IDNK other 9.04266420795334e-05 0.000867803093795955 1 0.99755117386603 -5.48087941303933 0.611985457024047 -0.511652710483055 7.77529956624456 -0.0658048871459986 0.94755747480903 15.6935948694046 17.1808971188655 0.913432794622363 0.361421854259629 SHC3 other 1 1 1 -0.0658048871459986 0.913432794622363 1.21805326339623e-20 7.38321812022301 7.88755542449767 0.93605911120342 0.349659630687421 -158.812074175161 17.4496155770588 -9.10117896144106 1.70024790178604e-18 AUH other 1.46032405748574e-16 2.60511983511657e-14 1 0.93605911120342 -9.10117896144106 4.35590829633046e-15 326.128493640479 45.8788714622579 7.10846808663913 3.71861302634615e-12 -196.667967965074 98.788629800811 -1.99079558408309 0.0470050408553511 MFSD14B other 4.50880067753166e-11 1 4.46345121552328e-08 7.10846808663913 -1.99079558408309 0.614907329449283 -0.473384306091791 3.75804520357528 -0.125965569983413 0.899805718285217 -7.58046669730084 7.85476312094596 -0.965078969356356 0.334934075054278 PLPPR1 other 1 1 1 -0.125965569983413 -0.965078969356356 2.21151297965067e-05 97.8463145430744 38.972435346328 2.51065435540695 0.0123386445067538 372.044381861247 81.659997446386 4.55601755443984 6.43629709023547e-06 ZNF462 other 0.129948502684273 0.0785936237688654 1 2.51065435540695 4.55601755443984 1.31329301805948e-22 112.616544692375 23.8174876168863 4.72831335125924 2.88907061029298e-06 -389.412428986621 52.8621163123658 -7.36656903188583 6.5471398341628e-13 INIP other 1.63504980748405e-18 9.63608040792082e-09 0.0270301446299011 4.72831335125924 -7.36656903188583 1.05472853215365e-06 -698.146497850785 319.21618430445 -2.18706485503546 0.0291628518085708 -3648.8703920603 689.653862217396 -5.29087212000574 1.76761400731829e-07 UGCG other 0.00702449202414333 0.00231292292857598 1 -2.18706485503546 -5.29087212000574 1.82928872828857e-12 78.4830638729516 25.7968550832368 3.04235007018166 0.0024610884243392 -316.646228118935 57.4998372159726 -5.5069065140062 5.64702563157084e-08 SNX30 other 1.71129960531396e-08 0.000753595570533128 1 3.04235007018166 -5.5069065140062 2.69366050107313e-12 189.552701438098 276.963076340564 0.684397010397941 0.494016495772845 -4767.87453613449 683.090406143981 -6.97985873209516 8.64942733519281e-12 STOM other 2.50375743574747e-08 1.25650230898346e-07 1 0.684397010397941 -6.97985873209516 0.0342125916112451 320.345521941699 826.617503473018 0.387537791778873 0.698509970266004 -4857.56548668387 2042.72427030583 -2.37798392925375 0.0177526719324055 GSN other 1 1 1 0.387537791778873 -2.37798392925375 6.30301542395359e-31 112.282232541472 14.1667038835459 7.92578382836698 1.30220402917067e-14 -257.545321259589 35.2523427137424 -7.30576470763717 9.94004997895582e-13 MRRF other 8.69942188814075e-27 1.46059094390777e-08 1.653408455838e-10 7.92578382836698 -7.30576470763717 0.000328604017086187 6.16914512316016 7.77152509464322 0.793813961613847 0.427650499034728 -61.9411492824329 17.6330620507167 -3.51278462607776 0.000480379815515814 NR6A1 other 1 1 1 0.793813961613847 -3.51278462607776 4.59703095355255e-07 11.1788766117507 3.40839169594582 3.27980983671791 0.00110548705577359 -27.5023183151951 8.36253260656517 -3.28875468821537 0.00107161910124236 CRB2 other 0.00315907967128132 1 1 3.27980983671791 -3.28875468821537 1.16840602110457e-27 52.5566043612399 45.7753281061542 1.14814260291832 0.251412477996425 -1087.58299227624 101.560576189216 -10.7087123083073 2.02458714651033e-24 ALAD other 1.56239253142103e-23 3.15005514125542e-20 1 1.14814260291832 -10.7087123083073 3.20901519857031e-05 -27.2893372218825 49.3559325542175 -0.552908957639595 0.580554985811156 -489.776898105451 108.554561485088 -4.51180393900567 7.89586657083434e-06 ASTN2 other 0.185577348933321 0.0959426747022081 1 -0.552908957639595 -4.51180393900567 2.75946016228726e-16 28.9155091422943 11.9363438564647 2.42247621968713 0.0157395441407528 -188.199903735776 26.4447143387164 -7.11673044848295 3.49235131489994e-12 WDR31 other 2.96945508063732e-12 5.09988062514839e-08 1 2.42247621968713 -7.11673044848295 3.68695132621978e-13 277.264660703839 48.6027367232166 5.70471293175957 1.91195454527345e-08 -334.132971654773 107.833677009057 -3.09859573486221 0.00204449333208877 POLE3 other 3.54352891962983e-09 1 0.000202361269071742 5.70471293175957 -3.09859573486221 2.55243538921027e-23 1194.05290151654 127.776730082619 9.34483845958868 2.30808667295056e-19 -477.183264018313 304.610913938197 -1.56653370638955 0.117800961012237 SURF4 other 3.21377139855465e-19 1 3.15330801258506e-15 9.34483845958868 -1.56653370638955 0.135548038602693 5.97369372015594 6.89397301238716 0.866509588799136 0.386590689596856 32.8031084831179 16.4364513289724 1.99575369564695 0.0464561384781452 GBGT1 other 1 1 1 0.866509588799136 1.99575369564695 1.60330212580834e-13 113.256887739946 31.6138730515366 3.58250593197852 0.000370613897584578 -399.372486291635 75.3652934859743 -5.29915651912056 1.68855288149695e-07 SURF1 other 1.56546419563927e-09 0.0022116665641847 1 3.58250593197852 -5.29915651912056 1.07008757078334e-05 55.5360010918516 13.209381804901 4.20428464496698 3.05852739935454e-05 -23.3317366296866 31.4902553974249 -0.740919256932878 0.459059755992016 SURF2 other 0.0649222129194253 1 0.265357837168 4.20428464496698 -0.740919256932878 2.44216344644694e-13 109.279907417479 24.1339971001789 4.52804841916008 7.30878895190822e-06 -249.210108455735 57.4411858292189 -4.33852652688392 1.70804037132957e-05 SURF6 essential 2.36718902864102e-09 0.203427608225351 0.0665319058292205 4.52804841916008 -4.33852652688392 9.60213806507992e-18 129.460822903201 22.5258030539591 5.74722342165054 1.50697449902214e-08 -249.869655252301 53.6999612607217 -4.65306956254855 4.1054168338717e-06 MED22 essential 1.07697580537936e-13 0.050652632896309 0.000160236598481024 5.74722342165054 -4.65306956254855 1.09474971108273e-14 109.198594551699 16.1683639299033 6.75384318568786 3.68293979903495e-11 -79.1188697142963 38.6306562405331 -2.0480850550833 0.0410276757501212 REXO4 other 1.11609733044885e-10 1 4.29578098159437e-07 6.75384318568786 -2.0480850550833 6.14038251136816e-15 444.302668133173 312.475503973819 1.42187999533685 0.15562996918868 -5346.36170227991 744.920055374866 -7.17709459384801 2.32694450983904e-12 RPL7A essential 6.32643610146261e-11 3.40711215130632e-08 1 1.42187999533685 -7.17709459384801 0.0102898321142369 124.30976293135 45.2081973806893 2.74971731087975 0.00616198010280382 -23.4582418458615 105.350715069417 -0.222668083746792 0.823876961618389 GTF3C5 essential 1 1 1 2.74971731087975 -0.222668083746792 3.44479156930444e-15 119.086100099109 21.6946274038836 5.48919775768038 6.2103426312534e-08 -194.65462102545 47.6596397224687 -4.08426547407747 5.08927718132407e-05 ASB6 other 3.57913844050731e-11 0.586844551778479 0.000642087324645289 5.48919775768038 -4.08426547407747 5.53710387954708e-06 142.638275168631 31.8130649008396 4.48363826664392 8.96102251873029e-06 -36.673546610776 71.3198231479018 -0.514212528748466 0.60731299906644 PTGES2 other 0.0344186377152646 1 0.0810793317494717 4.48363826664392 -0.514212528748466 1.39646210821648e-09 102.229362607354 18.1225839495179 5.64099263615624 2.72604965473469e-08 -44.0885831462178 40.1098819254875 -1.09919503697671 0.27217100861629 NTMT1 other 1.13476510913671e-05 1 0.000286725902684995 5.64099263615624 -1.09919503697671 1.74145285525584e-13 275.150909333057 44.7151437091183 6.15341663940462 1.4734282566523e-09 -255.162202897216 100.268935693547 -2.54477821203837 0.0112103441301051 CIZ1 other 1.69756824330339e-09 1 1.62813822360079e-05 6.15341663940462 -2.54477821203837 3.50315974827714e-10 139.65053093996 35.2617687255366 3.9603949542901 8.48136805565685e-05 -299.285368582567 79.0512676859726 -3.78596545436139 0.000170214867789022 SLC25A25 other 2.94125292465348e-06 1 0.705565008550094 3.9603949542901 -3.78596545436139 1.39550372267455e-14 193.206502686141 107.012550811996 1.80545647421838 0.071554972257755 -1638.20364782667 236.400030689716 -6.92979456494605 1.1940237298038e-11 SH3GLB2 other 1.41741313112054e-10 1.73240902957233e-07 1 1.80545647421838 -6.92979456494605 4.83144325883115e-13 40.4208670255925 16.8028790494285 2.40559173857573 0.0164784241209364 -224.829716807124 37.0654210979757 -6.06575374424662 2.45778340611793e-09 MIGA2 other 4.61692717813904e-09 3.41312381607597e-05 1 2.40559173857573 -6.06575374424662 0.00682858766926855 -291.728245787911 175.555306549966 -1.66174552920666 0.0971420394994258 -1199.83893945318 385.667036624983 -3.11107464602915 0.00196221716214276 PTGES other 1 1 1 -1.66174552920666 -3.11107464602915 0.000594021805701992 -41.1276378180628 95.5644287718674 -0.430365548631522 0.667100824254603 746.508576088198 214.240224275278 3.48444639009062 0.000533056206399265 LCN2 other 1 1 1 -0.430365548631522 3.48444639009062 7.86256740369514e-25 83.7850273142238 20.7572713720933 4.03641816943564 6.21199483004004e-05 -390.539335647317 46.58253239577 -8.38381503884879 4.47464145369231e-16 LRSAM1 other 1.01395669238053e-20 6.7696850552911e-12 0.523484804327474 4.03641816943564 -8.38381503884879 0.460300957563565 4.86240822647723 14.6978451246561 0.330824565454183 0.740905092945572 -33.1783861845153 32.6732343752021 -1.0154607224835 0.310340174471901 HMCN2 other 1 1 1 0.330824565454183 -1.0154607224835 3.64158627457053e-22 554.488989629953 98.3998630532334 5.63505855013212 2.82099741629424e-08 -1374.34980350632 218.762810164703 -6.282374058331 6.86914191583727e-10 GPR107 other 4.50027231811426e-18 9.6580135336672e-06 0.000296430408504199 5.63505855013212 -6.282374058331 6.0827115145083e-05 26.5797893597402 6.04022185967103 4.40046574070507 1.30613692809341e-05 2.09475575071099 23.9745638472707 0.0873740921443064 0.930407101076611 IDI2 other 0.340023573661014 1 0.116585782201617 4.40046574070507 0.0873740921443064 4.85309468993886e-14 61.1005974124029 9.93681183655068 6.14891359698047 1.55796660934922e-09 -66.4229599767222 22.9838670367402 -2.88998191081352 0.00401385179595565 INPP5E other 4.82882921648917e-10 1 1.71906035675593e-05 6.14891359698047 -2.88998191081352 8.83815687747906e-20 550.820093388661 202.612222186079 2.71859262706663 0.00677585462003844 -3723.09062707932 467.403360154639 -7.96547681182169 1.05188873168354e-14 SEC16A essential 1.04246060369866e-15 1.57520337569611e-10 1 2.71859262706663 -7.96547681182169 1.26066053145154e-08 77.165478848305 14.5819327995101 5.29185533284707 1.82239627236547e-07 -43.2030270891615 33.9933197413651 -1.27092697676684 0.204351564289348 DPH7 other 9.68565486314219e-05 1 0.00183314841037243 5.29185533284707 -1.27092697676684 1.14296025816591e-08 547.732597314749 95.0742493405444 5.76110357025105 1.43781642530517e-08 864.690558342791 218.764128646535 3.95261583191229 8.80789808897426e-05 NOTCH1 og 8.80879470968467e-05 0.996965984690997 0.000153041180309483 5.76110357025105 3.95261583191229 0.000142104137169483 33.0023051376505 7.8471535179529 4.20564030793422 3.09380529598352e-05 35.9405331086107 18.2021138711506 1.97452523168611 0.0488808099176268 CACNA1B other 0.756562426290329 1 0.268201981108811 4.20564030793422 1.97452523168611 1.0851477732447e-11 89.55274917503 26.0420278322547 3.43877787674097 0.000631054046390489 -297.577703835967 60.4392141246715 -4.92358658440091 1.14169988472929e-06 NACC2 other 9.81624675677153e-08 0.0144596290400965 1 3.43877787674097 -4.92358658440091 2.877292588869e-28 80.7300533762271 6.87046269480344 11.7503080887534 1.49620129657954e-28 -29.4201202054337 38.7975289604623 -0.758298814221264 0.44860232159274 PROSER2 other 3.87139717832324e-24 1 2.18550123391374e-24 11.7503080887534 -0.758298814221264 5.50635049245261e-19 173.539989083746 18.206480921858 9.53177002346459 5.15241339173158e-20 86.551203728447 95.6219425449888 0.905139567602131 0.36579361829996 USP6NL other 6.36423989917673e-15 1 7.08765986166596e-16 9.53177002346459 0.905139567602131 0.00373182881916717 12.4496026640914 49.2787178184845 0.252636497360765 0.800647258741542 -616.470255068161 191.136030424782 -3.22529589893707 0.00133618466877317 COMMD3 other 1 1 1 0.252636497360765 -3.22529589893707 0.000573567371340683 69.4150837897618 26.7252996995208 2.59735473765357 0.00965070377540566 -233.733140240943 103.607280922837 -2.25595284577556 0.0244728561394648 MSRB2 other 1 1 1 2.59735473765357 -2.25595284577556 1.04846824941004e-26 56.9553192667375 4.92640894608638 11.5612243908382 8.33161877316633e-28 53.6785594701693 18.2188212311391 2.94632450635299 0.00335302131593521 PDSS1 other 1.3863895661949e-22 1 1.21258379624663e-23 11.5612243908382 2.94632450635299 3.73156857668814e-13 301.047413560601 39.6307344924366 7.59631173674198 1.3384145317275e-13 444.510784461922 154.906190576873 2.8695482266174 0.00427038736894767 FAM171A1 other 3.58529108848196e-09 1 1.66177548259286e-09 7.59631173674198 2.8695482266174 0.00710906862922549 34.3354837061939 14.6404071601774 2.34525470026462 0.0193718099793732 -91.6684388049788 55.9125562378297 -1.63949647401306 0.101686961637078 MINDY3 other 1 1 1 2.34525470026462 -1.63949647401306 1.21467852204551e-19 614.292153666502 63.4263486272438 9.68512561359464 1.40855291756e-20 648.391047304506 252.983550090277 2.56297710690331 0.0106447495131537 RSU1 other 1.42870487762993e-15 1 1.94760611911021e-16 9.68512561359464 2.56297710690331 6.79527431972318e-05 -39.8622879334719 16.8291053637696 -2.36865163488067 0.0181995633922875 -296.11912535694 73.6475544978889 -4.02075978456865 6.61573500581495e-05 ST8SIA6 other 0.377817252176609 0.7557815670643 1 -2.36865163488067 -4.02075978456865 1.73141863629994e-09 241.330771535318 40.0904313248343 6.01966014233984 3.25868451603218e-09 -162.500634937816 147.147922273257 -1.10433523237962 0.269946970095949 PARD3 other 1.40106396049391e-05 1 3.55326959628148e-05 6.01966014233984 -1.10433523237962 0.000143481288249553 -529.247554629404 144.705661004092 -3.657407394825 0.000281522441179674 -1616.31394876583 551.168881169314 -2.93252032904469 0.00351487052178374 ANKRD30A other 0.763463934775872 1 1 -3.657407394825 -2.93252032904469 0.000843788905580896 -125.684889564413 33.4560818102244 -3.75671276383603 0.000190848294304751 -160.313837175003 121.902171466679 -1.31510239109091 0.18903262805468 ZEB1 other 1 1 1 -3.75671276383603 -1.31510239109091 0.681504412274205 -4.84885701539181 7.52480276634742 -0.644383270359852 0.51960676667316 7.23386315180117 19.4978905764093 0.371007475062636 0.710780773922583 FAM13C other 1 1 1 -0.644383270359852 0.371007475062636 2.0493183407944e-12 89.7495343886169 13.4011630865537 6.69714515142859 5.42496069553039e-11 -34.4899941925747 34.0162724301292 -1.01392632786025 0.311079677759075 NRBF2 other 1.91201401196118e-08 1 6.2913269186066e-07 6.69714515142859 -1.01392632786025 0.637162739768777 1.01821584901554 1.99743413645868 0.50976191426305 0.610425770370986 4.28558276821779 4.68404388412982 0.914932241078682 0.36063405897555 CDHR1 other 1 1 1 0.50976191426305 0.914932241078682 1.56770534640168e-40 201.693045534261 15.1321150503263 13.328807299143 3.35643369281229e-35 -142.707913561254 49.9360204019965 -2.85781510846123 0.00443181776501243 POLR3A essential 2.30060759584446e-36 1 5.01887530086222e-31 13.328807299143 -2.85781510846123 3.40607567495916e-17 121.566563933097 24.5302243662884 4.95578687409662 9.65586135596828e-07 -359.31103435836 62.9162188778668 -5.71094450313131 1.85689005492699e-08 HERC4 other 3.76269179812739e-13 0.000251682878044804 0.00929666331352626 4.95578687409662 -5.71094450313131 4.08435254712609e-18 165.792639931419 20.4537409439434 8.1057367640374 3.66149466511609e-15 -96.1455862450243 52.6278745923836 -1.82689472052019 0.0682789151131103 CAMK2G other 4.62348708334674e-14 1 4.69476845961186e-11 8.1057367640374 -1.82689472052019 3.148488702465e-05 517.017393981457 285.64942366662 1.80997177359919 0.0708569802734286 -2058.23830172443 606.473842045058 -3.39377918556875 0.000740054923474221 ADIRF other 0.182266010985699 1 1 1.80997177359919 -3.39377918556875 2.51791249399769e-18 303.595666594353 134.195689179181 2.26233546287009 0.0240762081103394 -2230.9092266307 284.398098963794 -7.84431835078724 2.37205020819158e-14 GLUD1 other 2.86613979191757e-14 3.54004773070512e-10 1 2.26233546287009 -7.84431835078724 0.353364214223936 4.7541296028789 19.4932734404737 0.243885646882065 0.807411333188209 53.3616690742287 37.9304404238182 1.40682967236838 0.160048927847531 ANKRD1 other 1 1 1 0.243885646882065 1.40682967236838 0.669467797484165 1.76529616299642 2.38742430428584 0.739414506180322 0.459974860638728 3.49801647819097 4.64639602743101 0.752845099199394 0.451869258181452 HTR7 other 1 1 1 0.739414506180322 0.752845099199394 7.31770536034005e-22 107.876471664735 12.2836377476934 8.78212740236429 2.09621186881978e-17 -38.5373848109774 23.9063686881403 -1.6120133222113 0.107540080729742 RPP30 essential 8.99419165839395e-18 1 2.79278307282859e-13 8.78212740236429 -1.6120133222113 4.62305908067625e-15 34.5170585104455 14.8083954669361 2.33091144732827 0.020122525871383 -187.66403392345 28.5943148620537 -6.56298410466518 1.23128149384095e-10 FRA10AC1 other 4.78209231305151e-11 1.75753120430857e-06 1 2.33091144732827 -6.56298410466518 0.0204745231824451 304.962945047771 109.716184742837 2.77956206518274 0.00563154606459523 171.747036343877 204.867913451636 0.838330578226063 0.402213258843334 ADD3 other 1 1 1 2.77956206518274 0.838330578226063 0.332923056407013 23.7681306143941 17.9465698649296 1.32438292070736 0.185928985049938 -3.62445290020883 34.3216677436101 -0.105602470348593 0.915936478064402 HABP2 other 1 1 1 1.32438292070736 -0.105602470348593 4.15405378202267e-31 156.188357326994 28.3784347568368 5.50376927639976 5.75649282514229e-08 -637.254795004296 71.6351848021283 -8.89583515090427 8.77081019055775e-18 DNAJB12 other 5.74422556978095e-27 1.34026750521913e-13 0.000596084832043484 5.50376927639976 -8.89583515090427 9.54727320242183e-12 632.88649836389 107.591100098161 5.8823313246772 7.0776905789267e-09 -663.285630835117 291.600816116262 -2.27463571491057 0.0233169378575932 EIF4EBP2 other 8.66033152191684e-08 1 7.62408829161984e-05 5.8823313246772 -2.27463571491057 0.0265229588695645 209.897319046008 121.01331513602 1.73449771878476 0.0833941737366086 -285.622666940005 230.644006420116 -1.23837021118921 0.216110987059542 PLEKHS1 other 1 1 1 1.73449771878476 -1.23837021118921 0.828022899915412 1.29946849808818 34.6506267117534 0.037502020061513 0.970098411606383 -36.633237502481 66.643489887652 -0.549689663074931 0.582756601280909 TCF7L2 other 1 1 1 0.037502020061513 -0.549689663074931 1.18011197705115e-10 919.185194631112 168.529727708037 5.45414276241827 7.54819145037144e-08 2115.94952015853 354.057131706496 5.97629402339677 4.18444886040356e-09 MKI67 other 1.01359817708923e-06 5.77872387621732e-05 0.000776784382157725 5.45414276241827 5.97629402339677 0.00613923333068713 26.1856270981133 9.53467267102766 2.74635826541604 0.0062256525127003 49.5560206143133 19.8155802974582 2.50086143682958 0.0126821196942851 INA other 1 1 1 2.74635826541604 2.50086143682958 0.186128055033938 12.251970004799 6.98795263960927 1.75329894701233 0.0801331787781995 16.8049362616927 13.8744568658267 1.21121399015509 0.226357285333457 FUOM other 1 1 1 1.75329894701233 1.21121399015509 4.82692909764017e-29 32.8910200521547 11.3710850721294 2.89251376130945 0.00397790250439262 -219.293448349659 22.6185853909549 -9.69527689549291 1.40364201255379e-20 LRRC27 other 6.54772932094889e-25 2.16553889696799e-16 1 2.89251376130945 -9.69527689549291 5.29014867590683e-10 141.075628226345 29.0776536605092 4.85168541703701 1.61532976924594e-06 -128.017735275607 57.7331691095637 -2.21740356973406 0.0270221726211789 MTG1 other 4.4003456686193e-06 1 0.015348863467375 4.85168541703701 -2.21740356973406 9.21554758555636e-07 13.9860873379161 4.94954160781198 2.82573386510005 0.00489384563631486 -29.9767588786947 9.84317526727842 -3.04543585425591 0.00243811419346622 NKX6-2 other 0.00618086776563265 1 1 2.82573386510005 -3.04543585425591 6.02644290966784e-15 25.0220067961616 5.75380418155088 4.34877621946062 1.6444849095861e-05 -54.2948352062893 11.4240768431718 -4.75266719155007 2.59435134084642e-06 PAOX other 6.21024941841271e-11 0.0323359951123098 0.14553691449837 4.34877621946062 -4.75266719155007 7.97839270261929e-07 162.929540700593 43.4533606963539 3.74952680505249 0.000196076021699614 -205.960900948052 90.0038765763879 -2.28835588846276 0.0224980079515578 GSTO1 other 0.00537823452083566 1 1 3.74952680505249 -2.28835588846276 7.95069671307472e-11 41.8784625672271 6.01430419761946 6.96314339800158 9.61063026659993e-12 33.0696852909784 12.5288943944034 2.6394735441102 0.00854122782055077 TAF5 other 6.89643432892101e-07 1 1.14107013155341e-07 6.96314339800158 2.6394735441102 2.53449063486505e-09 211.358756433642 34.0946909063679 6.19916916138301 1.1227508891218e-09 45.9024638976604 69.4545001886845 0.660899780042457 0.508956367280727 PPRC1 essential 2.03114079478085e-05 1 1.24748851290323e-05 6.19916916138301 0.660899780042457 0.13111158637168 -50.3893608593693 33.2580787066765 -1.51510137743626 0.130325407320947 49.6904673106667 68.8866399080308 0.721336784273518 0.471011089977612 ITPRIP other 1 1 1 -1.51510137743626 0.721336784273518 1.21241252012709e-05 203.354901824796 42.3180540134007 4.80539350321734 1.99970106349826e-06 155.275697860797 87.7852884477917 1.76881229880727 0.0774844809951773 CNNM2 other 0.0731660739402649 1 0.018891175946868 4.80539350321734 1.76881229880727 8.92929156215002e-17 379.298975827373 45.76055322634 8.28877601088632 8.92692259307796e-16 -17.7078199068112 95.3094668361811 -0.185792875509917 0.852676193054236 PDCD11 essential 9.73917830683703e-13 1 1.15701843728883e-11 8.28877601088632 -0.185792875509917 0.0039428637069205 -395.969512057041 177.937539786355 -2.22532868855258 0.0264721779864047 -1074.56158936018 341.059837077868 -3.15065414493481 0.00171948591724474 ADAM12 other 1 1 1 -2.22532868855258 -3.15065414493481 4.87150907469606e-05 143.94531635297 49.795423533758 2.89073384937443 0.00399809305887424 -192.050399796632 92.470507906345 -2.07688271801365 0.0382846230109173 RGS10 other 0.275873558900038 1 1 2.89073384937443 -2.07688271801365 3.23707575873748e-32 148.864018542846 14.6784398959433 10.1416785161199 3.12617534407327e-22 -113.702168080301 33.4909424523069 -3.39501249456385 0.000736991718487369 BTBD10 other 4.51992888192515e-28 1 4.38321044992513e-18 10.1416785161199 -3.39501249456385 0.397543816827648 39.0763604353265 39.0700918749292 1.00016044396357 0.317679174640599 103.016988504231 82.5646221266039 1.24771343767874 0.212674813342908 ADM other 1 1 1 1.00016044396357 1.24771343767874 0.648220844790825 3.03181741834967 4.58514084634933 0.661226671098575 0.508750549503022 -4.72568420818931 12.0411351944384 -0.392461685038801 0.694872840770093 GAS2 other 1 1 1 0.661226671098575 -0.392461685038801 1.64246172942314e-23 194.087130118493 22.3978683358229 8.66542865635442 5.33183219138779e-17 -184.43180605529 56.698979798572 -3.25282406686151 0.00121458178650134 LIN7C other 2.07508614895319e-19 1 7.06521083680796e-13 8.66542865635442 -3.25282406686151 1.16304771879581e-05 -47.1766523736762 14.5128949800196 -3.25067138145945 0.0012251764786333 -174.576161724042 38.9369825429242 -4.48355651421084 9.02110288522855e-06 LRRC4C other 0.0703062346012067 0.109245555940118 1 -3.25067138145945 -4.48355651421084 4.89665747737563e-24 37.6188156653582 4.00193683716864 9.40015227526014 1.60662938469187e-19 -36.0212859461064 12.1113175690526 -2.97418391853167 0.00307099076668876 IMMP1L other 6.23589329743787e-20 1 2.19851165001235e-15 9.40015227526014 -2.97418391853167 0.684780435446855 9.60037493977902 13.4199395007519 0.715381387467589 0.474678644720423 -6.9372909593917 33.6629630284409 -0.206080818064963 0.836804459816298 SAA4 other 1 1 1 0.715381387467589 -0.206080818064963 5.46411004704011e-24 113.791079897073 23.0727827594562 4.93183163398165 1.08386136365815e-06 -353.642736108123 50.3824484902794 -7.01916533842838 6.67445815754465e-12 PGAP2 other 6.95144080184443e-20 9.715341294122e-08 0.0104083206752092 4.93183163398165 -7.01916533842838 5.54636314526949e-18 79.467819360106 18.0828743010614 4.39464534437656 1.34856187917471e-05 -262.109427899415 45.3853207126518 -5.77520272598512 1.33189508434405e-08 TUT1 essential 6.2585161731221e-14 0.000181470705241877 0.120318690859967 4.39464534437656 -5.77520272598512 0.335518293867883 -6.74602447371356 27.2549489472443 -0.247515579162207 0.804602454519073 63.2550383584902 54.3646493745773 1.16353253605403 0.245122652788274 SYT8 other 1 1 1 -0.247515579162207 1.16353253605403 2.07245420776885e-11 8.55520499837389 4.23210608732023 2.02150060084885 0.0437153073542473 -53.7842730866492 9.75515208728639 -5.51342230294335 5.43566824116658e-08 ZNF214 other 1.84945813501292e-07 0.000725824780242974 1 2.02150060084885 -5.51342230294335 1.09968642436636e-07 5.99437692446579 3.05622388968983 1.96136707938441 0.0503439839039492 -29.4113428503172 7.04470262360566 -4.1749587486865 3.46834222528698e-05 ZNF215 other 0.000793313786537894 0.403923135556922 1 1.96136707938441 -4.1749587486865 0.000151875678000074 69.1175825123497 61.146488980182 1.13036060884463 0.258835574902196 -551.901843462665 161.005606765792 -3.42784238728713 0.000655696445998022 HSD17B12 other 0.806156098824393 1 1 1.13036060884463 -3.42784238728713 1.8594293324973e-17 74.250997297835 9.99657930996902 7.42764049536312 4.41644537630976e-13 -103.194191526615 30.6343349238179 -3.36857946429195 0.000810201590790807 APIP other 2.06749947480375e-13 1 5.41058723051709e-09 7.42764049536312 -3.36857946429195 0.383709297987459 -14.6539787968605 32.076350275099 -0.456846825501728 0.647969032703308 -123.606147435036 89.2237393061988 -1.38535045040921 0.166530284760733 PAMR1 other 1 1 1 -0.456846825501728 -1.38535045040921 3.34801792356843e-06 170.837548406982 38.9184186689731 4.38963231934134 1.37291441878011e-05 -106.986743191367 110.328115464606 -0.969714226884346 0.332634635350447 DGKZ other 0.0212900459759716 1 0.122409049578434 4.38963231934134 -0.969714226884346 2.67159085737374e-27 578.643370783065 55.4857304884511 10.4286879831834 2.59480244058643e-23 -812.267847686061 248.33321712516 -3.27087876961976 0.00114093702230326 EIF3M essential 3.5569560675074e-23 1 3.67398077562633e-19 10.4286879831834 -3.27087876961976 9.02508868794416e-16 515.314638991292 146.860775458988 3.50886502798834 0.000488072698295564 -2193.92542262569 386.265900276386 -5.67983200447118 2.21917969468314e-08 TNKS1BP1 other 9.55756892053287e-12 0.000299922135736426 1 3.50886502798834 -5.67983200447118 0.54051643203134 12.7103264372118 12.17502389368 1.04396726841823 0.296969383952327 3.64236447928442 30.1349340874811 0.120868506588092 0.903840314221219 GLYAT other 1 1 1 1.04396726841823 0.120868506588092 0.0589823312196623 -296.538331706001 277.610460336754 -1.06818140550715 0.285931477298706 -1710.4576543363 717.424268372108 -2.38416475402688 0.0174735341444769 SERPING1 other 1 1 1 -1.06818140550715 -2.38416475402688 7.34446846124088e-20 801.958548559606 130.457700103916 6.14726879226604 1.55933551884538e-09 -1506.19297584561 340.29997033257 -4.42607436719323 1.16735567007036e-05 SSRP1 essential 8.67381725272548e-16 0.140316151542458 1.72041487794211e-05 6.14726879226604 -4.42607436719323 0.0124742347655447 -19.3136345250819 23.060583825216 -0.837517153575406 0.402685959687303 -177.156690910684 60.1392019827515 -2.94577721469425 0.00336553374494866 SLC43A1 other 1 1 1 -0.837517153575406 -2.94577721469425 6.86369717277363e-06 152.150745586342 47.3776684539233 3.21144434818094 0.00140129829994611 -351.202636228597 143.227615797686 -2.45205950174219 0.0145274437301132 PTPRJ other 0.0423009656758039 1 1 3.21144434818094 -2.45205950174219 6.27885936579722e-18 98.078725451499 20.0158874910775 4.9000438024654 1.26794237105903e-06 -328.213011813989 58.2157727223003 -5.63787091480558 2.77548039584479e-08 C11orf49 other 7.07627450525347e-14 0.000374134757359878 0.0121329405486638 4.9000438024654 -5.63787091480558 8.29422368182531e-28 328.965559142311 47.8078804323367 6.88099025029779 1.64962636950852e-11 -930.191019823775 139.875872214021 -6.65011774439918 7.1762212249475e-11 ARFGAP2 other 1.11059655099641e-23 1.02806545268598e-06 1.94507445228749e-07 6.88099025029779 -6.65011774439918 7.85357259797381e-28 490.503791999893 52.4483353957849 9.35213269016949 2.27116266767325e-19 -568.181882640781 149.349837518055 -3.80436893727516 0.000158413262668038 CELF1 other 1.05198604949859e-23 1 3.10331666910873e-15 9.35213269016949 -3.80436893727516 5.80085630562827e-47 119.032844927309 9.84508726561083 12.0905830203348 7.3437874119371e-30 -79.6525175374164 22.3704866074194 -3.56060728294568 0.00040361838727035 HIKESHI other 8.70418488659522e-43 1 1.07887580868768e-25 12.0905830203348 -3.56060728294568 0.165564799748346 -342.096584591258 262.713236709879 -1.30216729417804 0.193418480804977 -988.394147609336 527.522306099962 -1.87365375109284 0.061522033779173 SESN3 other 1 1 1 -1.30216729417804 -1.87365375109284 3.69199187780254e-14 369.433760006197 74.9031892756136 4.93214993352059 1.08609305608201e-06 -404.010893467172 152.397845082429 -2.65102759982367 0.00826162963481475 ENDOD1 other 3.69125347942698e-10 1 0.0104286655244995 4.93214993352059 -2.65102759982367 6.13345152634859e-08 76.4878310043498 15.113134649904 5.06101697471712 5.74055455385596e-07 11.9428542148018 29.6657648322336 0.402580357605518 0.687417468078324 CCDC82 other 0.000450992690732412 1 0.00560278124456342 5.06101697471712 0.402580357605518 9.82085832563383e-28 68.2469594752982 6.05506256175905 11.271057694154 1.77015806795078e-26 -12.5561912731793 27.9078191213501 -0.449916606474402 0.652960624331204 KLHL35 other 1.31432546971958e-23 1 2.55805542399567e-22 11.271057694154 -0.449916606474402 0.363542481591452 -2.94849365794547 10.5323458502466 -0.279946528519705 0.779633615147457 -61.0481647393429 43.1427621925202 -1.41502680025265 0.15767941373891 TENM4 other 1 1 1 -0.279946528519705 -1.41502680025265 3.85677253648781e-05 486.444915002672 130.315863024555 3.73281428455885 0.000210618618911326 -887.321624145639 600.034647052446 -1.47878398106582 0.139814202843201 SERPINH1 other 0.221301608143671 1 1 3.73281428455885 -1.47878398106582 3.10977043805608e-07 21.9129190525854 4.17878100140111 5.24385437888183 2.31319322714575e-07 -16.4473677681191 26.6423833339999 -0.617338455119727 0.537288658833219 CAPN5 other 0.00216657706419367 1 0.00231434982375933 5.24385437888183 -0.617338455119727 1.54972935672932e-132 255.3886946728 7.74923430585646 32.9566360485179 7.65033246514633e-128 -66.1931724357658 44.7025210894949 -1.48074808360912 0.139298567130688 INTS4 essential 2.42625628089542e-128 1 1.19750654076935e-123 32.9566360485179 -1.48074808360912 4.08734259540677e-14 1341.36743482815 167.981123406836 7.9852271947216 9.47172153739812e-15 549.681646506072 1022.58689407432 0.53754028111583 0.591130319066259 PAK1 other 4.0795766444755e-10 1 1.20631845500302e-10 7.9852271947216 0.53754028111583 6.57155062903234e-31 4365.15718049672 403.431786880088 10.8200625792389 1.01243840029053e-24 -6104.68212425167 1853.79281326491 -3.29307681018575 0.00105919198960697 RPS3 essential 9.06742555793882e-27 1 1.44717944937528e-20 10.8200625792389 -3.29307681018575 3.15599455221626e-08 72.7274383345687 12.4668309003917 5.83367488623623 9.33138239191277e-09 54.0650700677802 23.5099924059388 2.29966344243152 0.0218464954423875 ZC3H12C other 0.000236878507944087 1 9.99764309469534e-05 5.83367488623623 2.29966344243152 9.46372505663904e-30 3.62579470168167 18.4934551214158 0.196058263741259 0.844637376059915 -339.87682972948 33.7868791639229 -10.0594324820741 5.89383331223307e-22 TTC12 other 1.29227165648406e-25 9.12895841731781e-18 1 0.196058263741259 -10.0594324820741 0.928151111562386 6.01499420652323 27.0369013529005 0.22247350493358 0.824028187487374 19.1448265466087 49.5791135406125 0.38614701190505 0.699537667117609 NCAM1 other 1 1 1 0.22247350493358 0.38614701190505 0.0213751104413808 14.0477250477198 8.02889871624417 1.74964531801831 0.0807444245659147 40.7599892072628 14.6958362991137 2.77357398229328 0.00573509661367514 DRD2 other 1 1 1 1.74964531801831 2.77357398229328 3.31863622841801e-20 41.3437129368927 22.7716711662776 1.8155765835104 0.0699857714586 -294.077276017897 42.1006375716246 -6.98510267255673 8.34249309689161e-12 C11orf52 other 3.94453102109765e-16 1.21241452177126e-07 1 1.8155765835104 -6.98510267255673 2.45013748248783e-21 83.4730906596648 18.6627850339016 4.47270278835839 9.42476667016199e-06 -174.067953357459 35.692657034003 -4.87685613294721 1.420708193849e-06 NPAT essential 2.97887715120871e-17 0.0179080267834666 0.0851056430315628 4.47270278835839 -4.87685613294721 5.61868345267902e-19 88.9722126944127 42.6432230096487 2.08643264779216 0.0374080248350965 -520.456969135516 81.4875951393147 -6.38694721872355 3.65389798784021e-10 ATM ts 6.49182686122533e-15 5.16770792420241e-06 1 2.08643264779216 -6.38694721872355 1.80366224184413e-36 190.772117404125 30.4774602264546 6.25944931062641 7.85005814746693e-10 -393.021490665877 59.8490893987513 -6.56687502874651 1.20364024750328e-10 AASDHPPT essential 2.59528959978952e-32 1.71843718136043e-06 8.77479499723853e-06 6.25944931062641 -6.56687502874651 4.09683202286399e-14 129.937301966784 40.6531891215799 3.19623883819263 0.0014784444266427 -298.205523737515 72.8980981601966 -4.09071747087552 4.99567671021587e-05 GLB1L2 other 4.08863835881826e-10 0.576501092358911 1 3.19623883819263 -4.09071747087552 8.03489681157044e-18 73.8912027655849 10.4328584984016 7.08254624338147 4.44076680341605e-12 -161.852784392008 40.6068090975536 -3.98585330857133 7.64988302976179e-05 SLX4IP other 9.03202750588633e-14 0.869715201653618 5.31915047713174e-08 7.08254624338147 -3.98585330857133 3.19524990995702e-44 511.385055020052 39.3618019225085 12.9919117022848 1.75190001966052e-33 -521.352535990087 128.38184866052 -4.0609520849688 5.66737458391631e-05 LAMTOR1 other 4.758366165908e-40 0.650954644708627 2.60665203925288e-29 12.9919117022848 -4.0609520849688 0.000346216533184809 15.0823854645389 6.03596457704227 2.49875314409641 0.0127681966525155 -59.6269485100771 25.9346359651269 -2.29912417472352 0.0218903893671084 P4HA3 other 1 1 1 2.49875314409641 -2.29912417472352 0.00126724198791311 -23.6593832544894 8.51553862238658 -2.77837777545756 0.0056521719072107 -54.9605346124492 15.3362543066571 -3.58370000350034 0.0003692477256171 GRIK4 other 1 1 1 -2.77837777545756 -3.58370000350034 3.64691033028855e-14 1058.47834640527 215.359946054353 4.91492668807657 1.17973272812578e-06 -1005.48381193571 411.357802413316 -2.44430470514193 0.0148319454748221 ST14 other 3.64829602771456e-10 1 0.0113065584663574 4.91492668807657 -2.44430470514193 2.05086356660294e-21 1249.91326899861 195.721067573648 6.38619686931902 3.6705967235994e-10 -1056.01346375544 362.635870815525 -2.91204910694739 0.00373911048033979 HYOU1 essential 2.49713147869574e-17 1 4.15658372980396e-06 6.38619686931902 -2.91204910694739 0.793236939654122 -0.629721544785271 3.37174112835167 -0.186764499649806 0.851916481301902 -10.0689640366846 14.8034012870955 -0.680179091372872 0.496686950487348 GGTLC1 other 1 1 1 -0.186764499649806 -0.680179091372872 0.230856482928206 -8.83597835200863 9.15401700827034 -0.965256929720104 0.334859705989543 -59.8192055181785 36.8361380654923 -1.62392717205652 0.104990425341512 ADAM33 other 1 1 1 -0.965256929720104 -1.62392717205652 1.28523973418103e-77 184.79108384054 8.90428769707249 20.753045064042 7.12092249244436e-71 -237.370915136014 54.7549973458591 -4.3351461353685 1.73633277268299e-05 KAT14 other 1.99700549897049e-73 0.206571509966096 1.10580805385168e-66 20.753045064042 -4.3351461353685 1.0823478799748e-13 254.398908563424 51.9849175844974 4.8937061052356 1.32349934857438e-06 -538.13689418266 137.022349428146 -3.92736583797124 9.75058960084715e-05 TKFC other 1.06340679207524e-09 1 0.012650006773674 4.8937061052356 -3.92736583797124 8.46015864866976e-25 374.793129036936 57.308301174123 6.53994484844667 1.49036403444318e-10 -819.11112022683 143.844589394139 -5.69441731299631 2.08652144025169e-08 MTA2 other 1.09042984822705e-20 0.000282222890008443 1.70751007426155e-06 6.53994484844667 -5.69441731299631 1.77172622485213e-32 96.3949496176486 12.4299851003743 7.75503340022071 4.71878767387595e-14 -218.797924302121 32.7630751562075 -6.67818644186904 6.24938205050265e-11 TMEM138 other 2.48041671479298e-28 8.96348867503595e-07 5.92302228824909e-10 7.75503340022071 -6.67818644186904 0.000343648041454307 15.4210150675302 4.49722686816845 3.42900536699198 0.00065445773995686 -6.6476572513968 11.2873694928798 -0.588946543797494 0.556155867266349 ROM1 other 1 1 1 3.42900536699198 -0.588946543797494 8.19274462730449e-05 18.4471381552213 26.0860864971465 0.707163880532221 0.479785120298484 -241.853267966009 65.4721910963833 -3.69398463555267 0.000244422967592879 EML3 other 0.45068288194802 1 1 0.707163880532221 -3.69398463555267 2.68266989294883e-11 152.489869580729 24.9263056795663 6.11762816122946 1.86237888933561e-09 -63.0703330164149 61.407942761879 -1.02707125788242 0.304861688747599 INCENP essential 2.38167433095997e-07 1 2.05010668138064e-05 6.11762816122946 -1.02707125788242 0.0207851992448203 3.61662709586755 15.7207630676378 0.230054169782166 0.81813679670216 -78.1953920562493 32.1707267501926 -2.43063803511312 0.015396827812859 PLCH2 other 1 1 1 0.230054169782166 -2.43063803511312 1.62580585117061e-26 243.67738470643 41.5487200591247 5.86485899829578 8.0351517614587e-09 -769.027693590887 110.021083263016 -6.98982113957605 8.54733376778993e-12 CPSF7 other 2.14427533710892e-22 1.24192759645988e-07 8.6289494766305e-05 5.86485899829578 -6.98982113957605 0.0388242433477681 -20.7935474367109 8.35590609977147 -2.48848505337795 0.0131308138697328 -33.5112499052909 21.8796586395379 -1.53161666995727 0.126205928422665 MS4A2 other 1 1 1 -2.48848505337795 -1.53161666995727 1.55804168750655e-09 150.795451596468 35.8546006737062 4.20574901862045 3.06914098681659e-05 -258.270317816707 89.7962231364272 -2.87618241386743 0.00419196009649671 B3GAT3 other 1.26310439606156e-05 1 0.266217289196471 4.20574901862045 -2.87618241386743 1.04079396453731e-57 729.941209112219 81.3021031085855 8.97813440492829 4.39674202961249e-18 -1129.02970208076 145.375860217874 -7.76628045666378 3.9988702476161e-14 EI24 other 1.59470451246407e-53 5.95631723382418e-10 5.91537672664065e-14 8.97813440492829 -7.76628045666378 4.1796693686783e-17 17.7514620835434 6.24975260982372 2.84034636117285 0.00467551018700458 -58.6519057628611 11.2141822081537 -5.23015451989143 2.42173083653955e-07 CCDC15 other 4.60724954509409e-13 0.00315188268375623 1 2.84034636117285 -5.23015451989143 0.00355481838092142 30.7404700461956 13.0605093604373 2.35369610769654 0.0189399901084404 -65.2914619692548 44.4821179279812 -1.46781369706733 0.142728540790497 CHEK1 essential 1 1 1 2.35369610769654 -1.46781369706733 0.862821329201521 -3.11696127986081 8.36486628987864 -0.372625356083968 0.709571369394273 -8.05399547943384 14.9571731357855 -0.538470431967147 0.590470960781443 FEZ1 other 1 1 1 -0.372625356083968 -0.538470431967147 0.0104405918206889 -105.469820750118 34.8217026681314 -3.02885306199122 0.00257334564287665 -119.778496866407 62.7591594280285 -1.90854208306865 0.0568560495177532 ESAM other 1 1 1 -3.02885306199122 -1.90854208306865 0.294951990690687 2.60784778021577 3.88698192672981 0.670918421894953 0.502557776133142 11.2632037297214 7.27389883227963 1.5484410753334 0.122098740581346 KIRREL3 other 1 1 1 0.670918421894953 1.5484410753334 2.12151715141204e-11 140.987085311167 50.2650640220088 2.80487229160666 0.00521299582444596 -351.724540697125 92.7246378650275 -3.79321557673921 0.000165317297346983 MPZL2 other 1.89281760248982e-07 1 1 2.80487229160666 -3.79321557673921 0.00548310548318106 -9.44393282096972 4.22069106925083 -2.23753235335606 0.0256541654397302 -24.9604097798724 7.78596543247372 -3.20582078052484 0.00142554369291928 SCN2B other 1 1 1 -2.23753235335606 -3.20582078052484 2.54564494821006e-12 17.6457830481791 50.7149413572736 0.347940519616679 0.728018707503629 -552.344036096228 93.0084242621451 -5.93864524077347 5.11245870180428e-09 SIDT2 other 2.3666861083509e-08 7.04599058282667e-05 1 0.347940519616679 -5.93864524077347 5.57528797383645e-24 -44.1989196604306 64.2831906192144 -0.687565742065382 0.492019321880482 -1107.95329953837 118.816340745203 -9.3249235971198 2.77295231061739e-19 TMEM25 other 7.09009371632781e-20 4.25870015864619e-15 1 -0.687565742065382 -9.3249235971198 0.999105902076106 -22.1293539583787 703.801605093931 -0.0314426022876508 0.974928035236418 -53.1624749982878 1290.73358917661 -0.0411877985078248 0.967161209778825 TAGLN other 1 1 1 -0.0314426022876508 -0.0411877985078248 0.337835713248383 5.34972134820365 16.1558836329426 0.331131460819346 0.740675575147571 146.74139315542 99.8532231416827 1.46957092158365 0.142269101800605 JPH2 other 1 1 1 0.331131460819346 1.46957092158365 0.039213054737135 17.5989463168938 7.6882219725468 2.28907885070649 0.0224679417984319 -38.5260783359534 45.1775153681094 -0.852771074771164 0.394172197459443 DUSP15 other 1 1 1 2.28907885070649 -0.852771074771164 2.40119350841795e-25 288.835535950069 27.0128152264077 10.6925373578872 2.42173370258335e-24 -292.562517696995 154.521204469147 -1.89334867471481 0.0588438734760781 COMMD7 other 3.11698929327734e-21 1 3.45315008651359e-20 10.6925373578872 -1.89334867471481 0.0125355031813929 -3.58012297779935 10.6802426600832 -0.335209890986826 0.7375979114981 214.940449734344 74.5970521758706 2.88135312944536 0.00411834804523559 KIAA1755 other 1 1 1 -0.335209890986826 2.88135312944536 7.5632475859899e-35 169.618274898643 12.5441453323562 13.5217083671003 5.29034639796219e-36 128.55460259742 82.7993755916739 1.55260352724624 0.12111478690774 DSN1 essential 1.0776871485277e-30 1 7.92388083486777e-32 13.5217083671003 1.55260352724624 9.49665401807984e-27 669.049334761827 60.9688232509208 10.9736304407306 2.18246699100238e-25 -899.022340586941 402.433195884152 -2.23396665528989 0.0259015814918989 SOGA1 other 1.25631236005178e-22 1 3.13227662548661e-21 10.9736304407306 -2.23396665528989 5.77885225068365e-11 7.61836425869999 1.11512454709858 6.83185055743061 2.30376978978416e-11 -5.52453214635325 7.52558273089542 -0.734100247635697 0.463211661268325 CNBD2 other 5.0472495557471e-07 1 2.70416497924864e-07 6.83185055743061 -0.734100247635697 6.3076918621256e-47 404.288053450043 24.9274756404111 16.2185717993295 3.87250186378414e-48 303.863352880936 154.113354978329 1.97168735262213 0.0491769870623087 LSM14B other 9.46279933156083e-43 1 5.92376610103061e-44 16.2185717993295 1.97168735262213 2.22074654140917e-69 449.346989712079 21.5291069069849 20.8716038084372 1.36039688986476e-70 284.750047452032 151.904948518744 1.87452779009958 0.0614224235927248 YTHDF1 other 3.43505075025171e-65 1 2.11201617151504e-66 20.8716038084372 1.87452779009958 1.22258755227481e-37 127.038158718702 9.36549523699598 13.5644891705108 4.6942801595634e-36 404.479891633147 69.4042067887525 5.82788724701189 9.90669254458863e-09 CABLES2 other 1.77104032822529e-33 0.000135483927239794 7.03297053505789e-32 13.5644891705108 5.82788724701189 1.21446456442716e-29 730.506474261687 60.7779113221265 12.0192757265046 2.61580940984003e-29 -657.675623223265 587.370395944893 -1.11969487696988 0.263397998532336 ORAOV1 essential 1.65665111233509e-25 1 3.83242236635663e-25 12.0192757265046 -1.11969487696988 7.70431844170335e-17 114.65435839297 20.4168307034242 5.6156785574825 3.16633209381425e-08 -196.621995362428 48.6462074494066 -4.04187717134827 6.09009409498678e-05 TRPT1 other 8.42467221600261e-13 0.697802981403586 0.000331863266752671 5.6156785574825 -4.04187717134827 4.78038760227667e-10 102.028999909103 27.7291166967151 3.67948972284392 0.000257592345869688 -237.461049919132 66.0820139811162 -3.59342937076629 0.000356783329598748 NUDT22 other 3.98636522153852e-06 1 1 3.67948972284392 -3.59342937076629 0.42207590221768 15.7994884118189 22.8182712187311 0.692405145874914 0.488986182750223 -40.6576533341216 54.3095408365586 -0.748628191434695 0.454413425661311 FERMT3 other 1 1 1 0.692405145874914 -0.748628191434695 2.10733103935556e-16 183.396095714303 35.8515345797835 5.11543223641308 4.38234613750463e-07 -381.712930778618 85.8237650921845 -4.44763673987752 1.05841010127973e-05 PLCB3 other 2.27511876953574e-12 0.127601921810284 0.00431617271082831 5.11543223641308 -4.44763673987752 4.41535920206345e-19 191.565975488083 44.480774066736 4.30671406933409 1.97930500063825e-05 -671.246060079022 107.63138561005 -6.23652716421355 9.2339725272948e-10 MRPL49 other 5.11828438703196e-15 1.294695288052e-05 0.174040288706121 4.30671406933409 -6.23652716421355 4.13588223908893e-10 53.5844063424654 13.0202161051161 4.11547749360399 4.49605425957179e-05 -113.631887145298 32.5119126141532 -3.49508466308536 0.000514631531901532 CDC42EP2 other 3.45966549299789e-06 1 0.383513428341474 4.11547749360399 -3.49508466308536 1.01475498682305e-09 549.845827256785 193.746857711726 2.83795997391037 0.00471663924836839 -2048.84191085887 468.814745036124 -4.37025911098636 1.49742369100213e-05 FAU essential 8.30272530218617e-06 0.178882234127114 1 2.83795997391037 -4.37025911098636 1.52560172947193e-05 237.020823995464 60.538994919019 3.91517606647615 0.000102343201301953 -145.317343283021 146.098007998918 -0.994656568377698 0.320365050654611 TM7SF2 other 0.0913225195261897 1 0.845150156351528 3.91517606647615 -0.994656568377698 7.15732496697572e-09 140.187753839115 61.7022609568685 2.27200351599936 0.0234938664437122 -668.023712390175 148.913091265932 -4.48599721294621 8.93951706864438e-06 VPS51 essential 5.59130226420144e-05 0.108293309769558 1 2.27200351599936 -4.48599721294621 2.38772013918332e-16 14.7355266799028 1.90400859074219 7.73921228693554 5.06514146751621e-14 -25.06627240243 11.4574199604779 -2.18777634833107 0.0291202663699631 TBX6 other 2.5737235380257e-12 1 6.35168740026533e-10 7.73921228693554 -2.18777634833107 3.12989993655486e-25 648.302273383659 62.413847964371 10.3871543660269 3.88468950105555e-23 -615.585090503945 375.576912286132 -1.6390386905225 0.10179639516332 PPP4C essential 4.0563503177751e-21 1 5.49217401659234e-19 10.3871543660269 -1.6390386905225 6.61905990404141e-16 8388.991740994 1102.20923801433 7.61107006878939 1.24578299643708e-13 -14427.9669220443 6632.57203021647 -2.17532005024804 0.0300457307558444 ALDOA essential 7.04003211393844e-12 1 1.54788537307307e-09 7.61107006878939 -2.17532005024804 6.68501319564442e-07 18.7061158358065 4.00786958424894 4.6673464399446 3.86310876371899e-06 -37.2572245054526 24.1295404944603 -1.54405031102877 0.12316852762055 FAM57B other 0.00453377594928605 1 0.0358187444572025 4.6673464399446 -1.54405031102877 6.70157819259006e-13 88.767337166662 12.6751784434148 7.00324161611941 7.55242944794626e-12 -108.92022152482 76.311423087935 -1.42731215219652 0.154074418315387 DOC2A other 6.37052022987611e-09 1 8.98814628600084e-08 7.00324161611941 -1.42731215219652 2.46367859952581e-30 189.220709900453 17.4606722422065 10.8369659126332 7.16904512708411e-25 -359.548707531518 105.122681532506 -3.42027716844663 0.000673427504644511 HIRIP3 other 3.38115250998922e-26 1 1.02617711949082e-20 10.8369659126332 -3.42027716844663 9.15167666660194e-29 275.784378875973 29.922059900175 9.21675779662349 7.01454577404179e-19 -988.617967746011 183.524383620455 -5.38684804843459 1.07676759102093e-07 TAOK2 other 1.23794730269125e-24 0.00142337907857057 9.52926043403577e-15 9.21675779662349 -5.38684804843459 3.57322316218819e-14 433.959993927059 66.6879272352465 6.50732466757039 1.76643771441022e-10 -1281.57398781982 408.915331987187 -3.1340815263439 0.00181882774258109 TMEM219 other 3.57643906303416e-10 1 2.01974488265664e-06 6.50732466757039 -3.1340815263439 0.172509759096591 4.94522643534466 5.75178130525196 0.85977302906652 0.390306592459725 46.0021304836012 25.8273367149035 1.78114108285334 0.0754674647509573 HMGA2 other 1 1 1 0.85977302906652 1.78114108285334 0.621556614450751 -15.917893592262 46.5363456155907 -0.34205293479102 0.732443401912802 -89.1329790935846 93.9003524069408 -0.949229441731 0.342926201741062 MMP3 other 1 1 1 -0.34205293479102 -0.949229441731 0.782617116796852 3.77411785092877 7.17560864068892 0.525964840045459 0.599128565935527 -1.15790142978356 14.1593525329572 -0.0817764390771708 0.934854793117282 CNTN5 other 1 1 1 0.525964840045459 -0.0817764390771708 0.627041395192072 -0.0727927606302953 2.57485389034742 -0.028270637376039 0.977456648079289 -8.1109954441048 8.74019094152613 -0.928011241215347 0.353812541776031 CLEC1A other 1 1 1 -0.028270637376039 -0.928011241215347 0.133553551276167 -76.9100059861311 59.9610721678326 -1.28266562297048 0.200154494154888 -390.378560955467 214.817091177319 -1.8172602506438 0.0697262996268632 MKX other 1 1 1 -1.28266562297048 -1.8172602506438 0.000438085282742559 -84.7152441113822 37.2324581908491 -2.27530623084681 0.0232757108087268 -504.408985390662 136.35005629146 -3.69936763584788 0.000238103249204139 MPP7 other 1 1 1 -2.27530623084681 -3.69936763584788 0.387368214134901 0.507211276309563 3.27328611738354 0.154954763537443 0.876914880046413 -15.5809078392527 11.9434059843931 -1.30456151784616 0.192597908096983 CCDC7 other 1 1 1 0.154954763537443 -1.30456151784616 0.00039853237284974 1308.58740482581 329.759304203216 3.96831078955513 8.21605759516968e-05 582.632160920254 1199.34643523256 0.485791380875934 0.627312139320246 ITGB1 other 1 1 0.684397597677635 3.96831078955513 0.485791380875934 8.98586025550577e-14 53.4024630826246 7.00157721030145 7.62720476809902 1.13761982651949e-13 -18.4527999418617 41.958107587269 -0.439791044042717 0.660269782947494 CTF1 other 8.85017376564763e-10 1 1.41463025427699e-09 7.62720476809902 -0.439791044042717 9.6737850956829e-53 218.472572832092 22.9600983268679 9.51531520997172 6.11236765131162e-20 -323.014399174544 46.6690679710014 -6.92138097498014 1.28197797378995e-11 CWC15 other 1.47060881024571e-48 1.85925265538757e-07 8.40022686319757e-16 9.51531520997172 -6.92138097498014 0.224402952959528 1.61666554181623 5.44518267237634 0.296898311606266 0.766668185080827 104.054076275809 61.6681330603459 1.68732327560469 0.0921686503360358 FCGR1A other 1 1 1 0.296898311606266 1.68732327560469 0.00392469766089156 -134.136003513152 82.2561952854202 -1.63071004010961 0.103542246570981 -688.390941651444 208.772751809676 -3.29732178018615 0.00104118716222303 ARID5B other 1 1 1 -1.63071004010961 -3.29732178018615 0.139917985644236 15.1497806340177 45.7431112331747 0.331192615141369 0.740636110044451 -136.143343849655 85.581290245035 -1.5908073301986 0.112277476318305 KLHL1 other 1 1 1 0.331192615141369 -1.5908073301986 0.984169756279494 0.310589213379591 2.13778077699025 0.14528581074476 0.884539833708878 0.7907497638228 4.65115065647382 0.170011642758158 0.865065129183726 CDH8 other 1 1 1 0.14528581074476 0.170011642758158 9.54848474127257e-33 78.3466946819553 8.1157935278733 9.65360865981588 1.88864843339711e-20 -140.860589910064 23.2606071996659 -6.05575721652216 2.61665417831811e-09 DCUN1D2 other 1.34003434859019e-28 3.63217766492337e-05 2.60860121620808e-16 9.65360865981588 -6.05575721652216 2.65941710349836e-29 454.529983017855 54.0764275677478 8.40532563746768 3.80569776710911e-16 -1007.67038268988 155.108211704064 -6.49656373198632 1.86823766344704e-10 TMCO3 other 3.61627537733707e-25 2.65719442872073e-06 4.96567444652397e-12 8.40532563746768 -6.49656373198632 1.92064131118189e-39 35.4171808343486 12.0818707844537 2.93143185076283 0.00351618317022396 -212.146642373409 21.6512475541472 -9.79835650776497 5.55619223250076e-21 TMEM218 other 2.80548076324338e-35 8.58376137999043e-17 1 2.93143185076283 -9.79835650776497 4.912515247597e-32 40.9589552472771 7.31583130881405 5.59867409708179 3.43308503863911e-08 -89.6326260842257 13.6195076210438 -6.5811943117336 1.10101002800547e-10 TIRAP other 6.85050251277402e-28 1.57257262300022e-06 0.000359135025892037 5.59867409708179 -6.5811943117336 6.74668783592351e-22 26.1858794042319 5.47855906981614 4.77970193814315 2.28363293878327e-06 -61.3360784121818 10.7928589094397 -5.6830242039517 2.19851922784401e-08 EEF1AKMT1 other 8.29910070696951e-18 0.000297173844027675 0.0215186731821548 4.77970193814315 -5.6830242039517 0.000875728751428464 53.8508301588068 20.6761804330848 2.60448637179804 0.00946092670099334 -47.5948452257566 42.0346559274652 -1.13227631285685 0.258033198252415 LATS2 other 1 1 1 2.60448637179804 -1.13227631285685 8.65931535903276e-56 652.733031778337 63.4287350691833 10.2908095371346 9.33716158717079e-23 -1029.584174822 128.950560437225 -7.98433268790032 8.91350578318847e-15 SAP18 essential 1.32210426901712e-51 1.33577797666862e-10 1.31551269601649e-18 10.2908095371346 -7.98433268790032 0.249137232791903 28.4768932594757 18.3920642125796 1.54832502378925 0.122142077795446 50.7599062135838 44.240009753064 1.14737556562289 0.251745079059811 ADGRL3 other 1 1 1 1.54832502378925 1.14737556562289 7.20072554964308e-25 21.0432658740485 5.71243961864063 3.68376162881108 0.000252791295956072 -101.01873833691 12.2807042628781 -8.22580987006322 1.43628075013084e-15 KIAA1328 other 9.29469653947929e-21 2.16619862734733e-11 1 3.68376162881108 -8.22580987006322 0.0343868493011495 2.61620270520102 6.85720105182555 0.381526323266331 0.702964503075908 30.3996687823515 12.6452393138267 2.40404060594657 0.0165546335531295 FAM124A other 1 1 1 0.381526323266331 2.40404060594657 2.20402306305091e-13 -69.5288157574785 41.0527125048628 -1.69364730160626 0.0909133067626668 -745.452441306502 95.596913959032 -7.79787140017893 3.30342947367759e-14 HNMT other 2.13944518730351e-09 4.92409197346382e-10 1 -1.69364730160626 -7.79787140017893 0.0599978168597511 42.9921486432497 18.5994656024347 2.31147225206416 0.0211802500224829 7.74637293765356 43.080015614069 0.179813605618187 0.857365982901904 LYPD1 other 1 1 1 2.31147225206416 0.179813605618187 5.7300400423423e-05 -107.280174377333 41.4588289871574 -2.58763156119446 0.00992930762134226 -419.314537574165 97.9304613938217 -4.28175801079825 2.20216960346032e-05 LYPD6B other 0.321455246375403 0.260230382040906 1 -2.58763156119446 -4.28175801079825 9.93478707872237e-10 -76.2848018826078 44.5303480448551 -1.71309691551853 0.0872644737123563 -535.672261599399 82.6920187862473 -6.47791974923326 2.08351259131203e-10 ADRA2A other 8.12963626651851e-06 2.96150479729092e-06 1 -1.71309691551853 -6.47791974923326 0.527510315753216 -75.6186775610105 126.041367007228 -0.599951264862703 0.548789916603676 -301.57767755027 268.308485217035 -1.1239960499435 0.261513187052159 GPM6A other 1 1 1 -0.599951264862703 -1.1239960499435 0.00606262212558616 14.8614080928179 8.91980748709515 1.66611309877695 0.0962697397647303 -33.3531798350755 18.9658008257295 -1.75859591385288 0.0792115184661781 WDR17 other 1 1 1 1.66611309877695 -1.75859591385288 0.654080274352823 5.86260460410459 14.2681199107771 0.410888374976188 0.681317991685899 -16.6342317638515 29.4683076389326 -0.564478692419884 0.572663656295787 VEGFC other 1 1 1 0.410888374976188 -0.564478692419884 0.179741939128363 1.62528038340727 3.76419655772757 0.43177351620247 0.666079654603235 -11.0798135451384 7.69287507377924 -1.4402695271763 0.150374990340975 CCDC102B other 1 1 1 0.43177351620247 -1.4402695271763 0.00637179603980837 -9.09853944392094 4.23369681376846 -2.14907676296788 0.0320770941650249 10.4233451116275 8.67321622265512 1.20178545582675 0.229979353704439 CD226 other 1 1 1 -2.14907676296788 1.20178545582675 1.18257520011603e-07 89.0311360218267 66.8788948939988 1.33122917421017 0.183673275485386 -496.041655862273 116.640260982269 -4.25274816504121 2.4871964155606e-05 FSIP1 other 0.000850862856483481 0.292668402219016 1 1.33122917421017 -4.25274816504121 0.00489160855571708 7.21832845930668 4.67402733166667 1.54434879111688 0.123112187775122 -19.6970191016572 11.0974854664525 -1.77490830343513 0.0764979521134347 DLG2 other 1 1 1 1.54434879111688 -1.77490830343513 0.36268421952854 -1.53048991891865 1.13128107230341 -1.35288210541914 0.176675614100124 -4.24640171522764 7.82520875720552 -0.542656668592709 0.587596496835091 RGS18 other 1 1 1 -1.35288210541914 -0.542656668592709 0.0460580937765938 -1540.73129313771 630.960309018795 -2.44188306477423 0.0149404875456729 -2303.75660527334 1430.91138653778 -1.60999250334256 0.108001708720288 PRSS23 other 1 1 1 -2.44188306477423 -1.60999250334256 1.11550779616297e-07 251.2854465468 46.2592869097302 5.43210808755342 8.46112884414778e-08 -122.221489969335 212.823993548535 -0.574284355497082 0.566016317368531 MTMR12 other 0.000804169570253882 1 0.000868111819409563 5.43210808755342 -0.574284355497082 0.233363445857181 -2.27699107629148 3.33087077425445 -0.683602346236665 0.494518976372484 -15.18547254253 8.97758269504589 -1.69148790474632 0.0913195480145907 PPP1R1C other 1 1 1 -0.683602346236665 -1.69148790474632 4.81770740429183e-31 1938.58169015619 153.784133303798 12.6058628319382 3.69342744160409e-32 1432.84878237173 715.484415125131 2.00262752350957 0.0457112271923823 CCT5 essential 6.65614454976959e-27 1 5.47033538375982e-28 12.6058628319382 2.00262752350957 1.28049346524959e-17 61.9865128018237 7.82060786280401 7.92604793505131 1.28050680847922e-14 -128.452305404007 36.3855680194748 -3.53030919663683 0.000450125247470101 FAM173B other 1.43082339806989e-13 1 1.62611559608776e-10 7.92604793505131 -3.53030919663683 8.26496405234545e-15 -124.310879606882 71.5926069069684 -1.73636475856256 0.0830675784513297 -1293.16259077665 157.459669663884 -8.21265911161282 1.59421520494719e-15 DOCK1 other 8.47324114646456e-11 2.40375768601938e-11 1 -1.73636475856256 -8.21265911161282 3.98480719784036e-16 27.4143162800384 39.7175490477814 0.690231822891643 0.490342776851916 -497.104875791321 73.4304533683113 -6.76973725462309 3.35028218441066e-11 DIXDC1 other 4.2657361052881e-12 4.82675154308044e-07 1 0.690231822891643 -6.76973725462309 6.78400734694174e-42 285.323640259125 32.3225447398535 8.82738789768996 1.46613355804893e-17 -303.811253628721 59.7584486245519 -5.08398829992216 5.09219663318865e-07 DLAT other 1.00172652484942e-37 0.00655060174893389 1.95802136677435e-13 8.82738789768996 -5.08398829992216 9.16278569189446e-45 6.47710822778908 2.99563633387248 2.16218108805487 0.0310394445319735 -64.203036808194 5.53838138043741 -11.5923827555414 6.36791344123632e-28 PIH1D2 other 1.36717925308757e-40 9.94795437789937e-24 1 2.16218108805487 -11.5923827555414 9.70905163595842e-29 137.488805225575 22.529218287497 6.10268867170937 1.98067545854036e-09 -213.760730809289 41.6566312143462 -5.13149346401472 4.00405434629638e-07 TIMM8B other 1.31295505273066e-24 0.00516923416106863 2.17696039648171e-05 6.10268867170937 -5.13149346401472 0.000143920806665854 0.569791790330502 17.4780850206644 0.0326003557973792 0.97400522148477 -112.422821308802 32.3170619036909 -3.47874511748118 0.000544041931072898 IL18 other 0.765658691462344 1 1 0.0326003557973792 -3.47874511748118 1.00032275050105e-23 115.23552945455 14.6520570514227 7.86480212642637 1.98972694833593e-14 -45.0656357139872 27.1006011169167 -1.66290170168426 0.096905993161392 PTS other 1.26790908626008e-19 1 2.51521383539145e-10 7.86480212642637 -1.66290170168426 0.262763181837173 -0.406027006444376 26.3921207397002 -0.0153844024301394 0.987731189226536 -163.702140027315 102.302262333699 -1.60018103503261 0.110143280399563 PIP4K2A other 1 1 1 -0.0153844024301394 -1.60018103503261 0.0517312279909117 -8.42827853139929 4.13103666826351 -2.04023328966047 0.041810371101896 -22.4655581500902 12.3017715901668 -1.82620511081898 0.0683683236152463 C2orf50 other 1 1 1 -2.04023328966047 -1.82620511081898 0.0230545326440406 59.5255237168476 30.2595171723025 1.96716700329023 0.0496792834357713 -35.8291068156839 58.4325732821616 -0.61317010022254 0.540023963425203 FREM2 other 1 1 1 1.96716700329023 -0.61317010022254 0.0147861444448463 -4.81887201613179 36.4300940851119 -0.13227723224852 0.89481383555647 -179.522393906625 70.4485604511652 -2.54827625656127 0.0110988806773026 FOXO1 og 1 1 1 -0.13227723224852 -2.54827625656127 0.00680646914642582 -294.453313032358 149.033869965538 -1.97574761428692 0.0486901347098308 -1339.61278820761 472.006410200994 -2.83812414250299 0.00470801568324119 CRIM1 other 1 1 1 -1.97574761428692 -2.83812414250299 8.61739722109494e-08 482.637299155557 102.296689938186 4.71801481990469 3.0344323336371e-06 -246.266183375489 216.677861924967 -1.13655442779276 0.256226855319633 SEC24D other 0.000626140082084759 1 0.0283415979961705 4.71801481990469 -1.13655442779276 2.36033518299437e-11 164.917813916494 32.4279728068332 5.08566523411363 5.11286200554019e-07 -228.722477024656 69.8092041459303 -3.27639427813173 0.00112116941422909 ABCB9 other 2.10046227934669e-07 1 0.00501111605162994 5.08566523411363 -3.27639427813173 1.34302576820496e-12 -44.9563917363751 20.4364359039917 -2.19981566000919 0.0282382393939732 -352.049535855451 46.4257228508687 -7.58307063923 1.46059025776392e-13 RILPL2 other 1.26311573499677e-08 2.16474082103191e-09 1 -2.19981566000919 -7.58307063923 4.29086717438194e-15 118.850564493988 17.6254539188904 6.7431207752674 3.96867919480502e-11 -111.147364242278 40.3121082186818 -2.75717071504508 0.00602624977463553 DHX37 essential 4.44233478563762e-11 1 4.62271752610889e-07 6.7431207752674 -2.75717071504508 1.12827989288563e-09 3911.26733737929 958.034973220741 4.08259348218815 5.12234321943134e-05 -8098.1055322122 2194.15960632988 -3.69075499742596 0.000246106933582552 UBC other 9.20789220583962e-06 1 0.434579598736555 4.08259348218815 -3.69075499742596 0.000366965584505731 96.1357426387829 160.396407588668 0.599363440142128 0.549186188482158 -1601.84438820852 421.340964040495 -3.80177700465546 0.000160324058006729 ITPR1 other 1 1 1 0.599363440142128 -3.80177700465546 0.000483255773486463 11.6804417231935 2.99262684049706 3.90307323490205 0.000107546883225467 25.4869476285655 17.6814693619873 1.44144963898526 0.150063109228137 PRSS53 other 1 1 0.885971224011397 3.90307323490205 1.44144963898526 0.226608317229484 59.7873336533034 34.7188178514379 1.72204404853685 0.0856341702021177 55.7254458869523 75.4943790032821 0.738140330746077 0.460749834434964 SLC7A11 other 1 1 1 1.72204404853685 0.738140330746077 0.00190300114785048 36.17290571071 23.462258545991 1.54174866157081 0.123720458775515 -124.572279974639 51.5630687735303 -2.41592059855422 0.0160262975771842 NOCT other 1 1 1 1.54174866157081 -2.41592059855422 0.0882518049788097 3.2343819653642 1.86654144116246 1.73282087074899 0.083697367646958 -6.54961511848955 6.9747955763228 -0.939040441661602 0.348129033149387 ENKUR other 1 1 1 1.73282087074899 -0.939040441661602 5.59818417617653e-06 45.744979390873 9.19809138444211 4.97331212301796 8.84770739621183e-07 37.7678539455273 34.0470538004799 1.10928405631958 0.267799602757241 GPR158 other 0.0347703219182324 1 0.0085415767203029 4.97331212301796 1.10928405631958 0.00321442636357142 -3.71577979927561 2.38384258657723 -1.55873538806554 0.119652561307416 -31.3672501073801 9.46645005957033 -3.31351772945431 0.000983872710562437 CACNA2D4 other 1 1 1 -1.55873538806554 -3.31351772945431 7.10908686079436e-39 65.0735886529673 6.7409648621441 9.65345317528763 1.92635833797246e-20 -213.233162318143 26.5085164900007 -8.04394928696129 5.58086070423083e-15 DCP1B other 1.03579395561774e-34 8.37854617526174e-11 2.66049350057376e-16 9.65345317528763 -8.04394928696129 0.00596585864998066 22.053259346885 10.0021048173294 2.2048618515451 0.0278869600413843 -84.3523017383012 46.4468535758274 -1.81610368074967 0.0699119461944373 CACNA1C other 1 1 1 2.2048618515451 -1.81610368074967 3.29092983659696e-11 55.405107693825 33.848324344833 1.63686412152579 0.10224363835964 -428.806869047 71.9394037861286 -5.9606675407238 4.54804249097756e-09 THRB other 2.90885288256805e-07 6.27538902905083e-05 1 1.63686412152579 -5.9606675407238 1.0744286345376e-13 94.9902596588897 18.9462360594822 5.0136744502003 7.26890485683723e-07 -159.635795927332 39.2254246204682 -4.06970217586971 5.41620142662486e-05 NGLY1 other 1.0558410191601e-09 0.62356727024732 0.00705519905404622 5.0136744502003 -4.06970217586971 1.01251718077693e-19 45.9563328433926 6.57803286196888 6.98633372738083 8.40206014853182e-12 -54.2495173424994 13.6188597760548 -3.98341111036937 7.73213900376806e-05 OXSM other 1.19264398723715e-15 0.878680276388202 9.99004951660433e-08 6.98633372738083 -3.98341111036937 2.2346941306379e-25 200.924715148669 28.7774724283609 6.98201399198121 8.48101840415526e-12 -414.324498695572 72.2211791137908 -5.73688360920787 1.59917205810963e-08 UEVLD other 2.90242073687251e-21 0.000217295499255937 1.00822346788598e-07 6.98201399198121 -5.73688360920787 0.0264545142104039 -6.31966139427816 50.8578631240622 -0.124261245087353 0.90115433186868 -343.579148564765 133.277321388981 -2.57792657433444 0.0102014423104866 TMEM86A other 1 1 1 -0.124261245087353 -2.57792657433444 0.000105983293032542 29.5553458054684 9.26933704053133 3.18850697479593 0.00151219887803722 -40.4882100228566 22.4905665137442 -1.80023077667314 0.0723770436099734 C12orf45 essential 0.57368756518515 1 1 3.18850697479593 -1.80023077667314 1.07688567365699e-08 237.020728326925 62.2560378762033 3.80719262601072 0.000156479469097637 -496.998403687529 143.525027496237 -3.46279957131908 0.000576498842229263 TMEM263 other 8.30924985793736e-05 1 1 3.80719262601072 -3.46279957131908 0.134703089711091 8.45736015517007 10.0475786414729 0.841731172947582 0.400306284819642 -34.2581867478769 23.2094536176895 -1.47604451669498 0.140507348380068 BTBD11 other 1 1 1 0.841731172947582 -1.47604451669498 1.19060351046387e-25 209.480230375441 39.0787283911926 5.36046690870967 1.22927619460966e-07 -700.78325155914 89.2282888016249 -7.85382372531141 2.17132696433555e-14 UBE3B other 1.5523088569428e-21 3.24309395393158e-10 0.00124832997562611 5.36046690870967 -7.85382372531141 9.52208035592552e-06 154.324095713679 66.4127359434885 2.3237123651252 0.0205218203995197 -572.15000652041 170.326881080785 -3.35912923955347 0.000838691872955879 ANK3 other 0.0580561239300779 1 1 2.3237123651252 -3.35912923955347 2.45961990602446e-09 73.6364347575228 12.3892319020426 5.94358353606915 5.05344228714421e-09 -16.6553597355744 33.4377717624815 -0.498100168093807 0.618619671872439 IPMK other 1.97310708861282e-05 1 5.47136196429104e-05 5.94358353606915 -0.498100168093807 5.54185571123861e-06 3.95218827734623 1.01582987739778 3.89060054767282 0.000112481805727348 -3.87407667875918 2.25091370164724 -1.72111293112841 0.0858031079156502 RAD9B other 0.034442633245348 1 0.924487961273075 3.89060054767282 -1.72111293112841 5.69585596481024e-09 268.711586145108 60.9252743517221 4.41051089230774 1.2442971104715e-05 -395.228700352268 135.959506312043 -2.90695892529333 0.00379896871459375 PLBD2 other 4.47580361714788e-05 1 0.111227718705048 4.41051089230774 -2.90695892529333 1.44639728436449e-06 382.420588138676 123.841564536047 3.08798253293516 0.00211975387598574 -1376.38642862898 410.028203071439 -3.35680916170826 0.000844519952411634 DLG5 other 0.00951295493926525 1 1 3.08798253293516 -3.35680916170826 4.15423780159462e-06 55.8953677027766 11.3547032893434 4.92266211440641 1.13421507023364e-06 81.556197798291 41.7284256904243 1.95445182627645 0.051160620423024 MAT1A other 0.0261384642476333 1 0.0108805251687513 4.92266211440641 1.95445182627645 0.267854116722524 -25.1356591986909 21.3426153001705 -1.17772160745877 0.239450503681091 -94.4326050597366 71.0043310140125 -1.32995556343036 0.184120473550405 SLC2A13 other 1 1 1 -1.17772160745877 -1.32995556343036 2.72611493855620e-09 107.46102949253 19.0593239093975 5.63823932073186 2.80894613578869e-08 -106.438781596173 60.3686314294079 -1.76314716891732 0.0784573745947549 GXYLT1 other 2.18007411636339e-05 1 0.000295220238871392 5.63823932073186 -1.76314716891732 3.2588195205403e-11 168.010692148388 55.5678401215398 3.02352389045371 0.00262062992168641 -957.567362959819 171.393544255512 -5.58695117204815 3.71541935744525e-08 TWF1 other 2.88177410201379e-07 0.000498795048737024 1 3.02352389045371 -5.58695117204815 2.47196387983179e-06 94.1356548783224 25.0942181795661 3.75128861177176 0.00019544007421194 -290.357831570932 100.302698674437 -2.89481574681631 0.00395109189683523 DIP2C other 0.0159293352416361 1 1 3.75128861177176 -2.89481574681631 1.06179086150549e-29 204.417849292615 24.00644904931 8.51512228537982 1.63804599558424e-16 -266.004617891841 54.3497428118784 -4.8943123578812 1.30253492084072e-06 EIF4E essential 1.44913216778269e-25 0.0164536211200599 2.15059058760255e-12 8.51512228537982 -4.8943123578812 3.6869675987291e-11 83.2953976391055 43.3927542417471 1.9195692712902 0.0554488715926384 -437.192589916381 84.6226828119262 -5.1663759099678 3.38490010396685e-07 MAGI1 other 3.25190542207907e-07 0.00438243016460588 1 1.9195692712902 -5.1663759099678 1.3825020337074e-40 128.791680329231 8.72342086648108 14.7638962169189 1.19706763896084e-41 120.313086746444 20.9932131548548 5.7310467844519 1.66542502127065e-08 TEX30 other 2.02951298548246e-36 0.000226041647049132 1.81439542037294e-37 14.7638962169189 5.7310467844519 9.63279401070643e-20 63.8632495567005 26.5189207901559 2.40821449945306 0.0163623888817198 -469.012140873896 60.0045483480686 -7.81627649546323 2.83196934759933e-14 CSNK1G3 other 1.13522477416175e-15 4.22444867581393e-10 1 2.40821449945306 -7.81627649546323 1.76085581075661e-06 27.0216961936186 10.7058081625845 2.52402208065488 0.0118866155019891 -79.4861254866229 24.2528913733514 -3.27738760146185 0.00111482768231195 SRFBP1 essential 0.0115036710116729 1 1 2.52402208065488 -3.27738760146185 0.692860750691322 -2.99567378991369 12.6513726764376 -0.236786463139526 0.812914289699431 -45.2566169179291 53.0097003589158 -0.853742175705719 0.393635011276965 AKAP6 other 1 1 1 -0.236786463139526 -0.853742175705719 0.10638544816068 18.1257400644427 11.22816846643 1.61430959275639 0.107057701550591 -26.7729369100633 29.9253237753572 -0.894658220276638 0.371377460622734 NPAS3 other 1 1 1 1.61430959275639 -0.894658220276638 4.192027795372e-10 41.2526325785554 7.90459336424821 5.2188178034733 2.58207179455583e-07 -47.5113508898091 20.1831090087162 -2.35401547250679 0.0189331515509112 MBIP other 3.50411603415146e-06 1 0.00257639123660781 5.2188178034733 -2.35401547250679 1.80793684913142e-06 -10.9945611283058 19.0567469443331 -0.576937982144705 0.56422493634517 -247.846900651459 48.5639790175017 -5.10351304949988 4.64540496751915e-07 MIPOL1 other 0.0117985958774316 0.00598560430064843 1 -0.576937982144705 -5.10351304949988 2.97945957016581e-11 260.430152036604 58.086535488364 4.48348571397883 9.00687934174671e-06 -555.790563970754 152.94840386106 -3.63384350500081 0.000306421121179649 EXT2 ts 2.6395032332099e-07 1 0.0814852374047825 4.48348571397883 -3.63384350500081 3.13484273686915e-15 108.907710770123 15.0650449207537 7.22916601596664 1.64833887158487e-12 -123.511062259452 46.7997341389634 -2.63914025435931 0.00854908338645144 TMEM18 other 3.26149038343866e-11 1 1.9956438718278e-08 7.22916601596664 -2.63914025435931 0.197932052342834 7.90826994824175 5.87816647745926 1.34536338475054 0.179108129451217 -28.8792465457349 34.2296267071458 -0.843691542207386 0.399238895368519 KCTD14 other 1 1 1 1.34536338475054 -0.843691542207386 0.112618370425457 9.40075917364541 22.1372315549214 0.424658302476648 0.67126557977115 -238.422232458532 126.458689423315 -1.88537643040427 0.0599494414462262 THRSP other 1 1 1 0.424658302476648 -1.88537643040427 3.73116379050632e-112 1154.283299695 40.278448651928 28.6575908042015 5.90429053837283e-108 -130.071992299165 206.002966990552 -0.631408344255209 0.528059250157774 NDUFC2 other 5.83479393559378e-108 1 9.23312954390743e-104 28.6575908042015 -0.631408344255209 0.00148283765064437 -10.8411660713714 16.4836632093032 -0.657691553977687 0.511025155267091 -129.093934084334 37.5117502005656 -3.44142657684866 0.000624863639444628 ME3 other 1 1 1 -0.657691553977687 -3.44142657684866 0.433141194684842 -31.6104924652332 47.0895202982715 -0.671285081372841 0.502325980587725 -260.121065799777 211.915556679451 -1.22747508430088 0.220178903343568 ADAMTS12 other 1 1 1 -0.671285081372841 -1.22747508430088 6.27066503788205e-70 137.525959890712 6.99769540979604 19.6530360121405 6.44643440682182e-65 -94.6528574517851 29.5754530051061 -3.20038571971978 0.00145511654733891 NUBPL other 9.70385414612246e-66 1 9.98359296584495e-61 19.6530360121405 -3.20038571971978 3.59169400212153e-11 197.559966683755 28.3311896548279 6.97323229595088 9.1693445120351e-12 -191.551105369587 200.032137784697 -0.957601650869527 0.338696192460515 NEK7 other 3.16895161807182e-07 1 1.08913474113953e-07 6.97323229595088 -0.957601650869527 2.42572308890419e-05 35.3901888824743 16.44268233065 2.15233671555554 0.0318092403177299 -108.005823620404 36.4348483553927 -2.96435496497457 0.00316586064128238 FER other 0.141979809659206 1 1 2.15233671555554 -2.96435496497457 1.92131202054774e-32 103.483767359939 11.1192784936467 9.30669803972147 3.21550262094433e-19 -97.8553207115689 23.3342005821607 -4.19364359053212 3.20449900733337e-05 VIPAS39 other 2.68810764794834e-28 0.374125259106172 4.3836947231334e-15 9.30669803972147 -4.19364359053212 2.06650884328617e-05 177.845903023462 136.58780868704 1.30206278827531 0.193464802039826 -1105.36533329534 298.818679319489 -3.69911725670105 0.00023910989320722 ANKRD50 other 0.121989932239598 1 1 1.30206278827531 -3.69911725670105 2.60379279628418e-69 488.301841285724 23.6229764085123 20.670631542847 2.13297228700263e-70 122.967060533125 134.707670492751 0.912843790433907 0.361731311516787 UPF2 essential 4.02704168807856e-65 1 3.31079958388548e-66 20.670631542847 0.912843790433907 1.19993535191083e-62 562.175661844438 29.0381772058608 19.3598812301129 9.27328828377844e-64 152.284703012597 168.038313904415 0.906249887149076 0.365209295080776 CDC123 essential 1.84862040315383e-58 1 1.43541229344606e-59 19.3598812301129 0.906249887149076 0.00682205883090249 24.2263906129543 8.18216294663049 2.9608785318717 0.00320324619528472 2.87435046587235 16.9166020059655 0.169912992269886 0.865142554581102 SCLT1 other 1 1 1 2.9608785318717 0.169912992269886 0.501922643603311 -5.67366489363228 35.298789110254 -0.160732564392248 0.872363929608525 222.816753232297 196.052038447039 1.13651842131949 0.256241902141546 CCDC3 other 1 1 1 -0.160732564392248 1.13651842131949 8.78208497426869e-10 14.4922692824576 10.1711405935178 1.4248420960471 0.154782676566922 -112.343064111832 21.2395552100909 -5.28933223886241 1.78899882309261e-07 C4orf33 other 7.20745713838232e-06 0.00234036826036975 1 1.4248420960471 -5.28933223886241 0.000304719592389213 86.3421358828609 21.34139682316 4.04575841957828 5.97201859135618e-05 29.2170218560907 116.260421670552 0.251306690929466 0.801672076552353 FRMD4A other 1 1 0.503739768180894 4.04575841957828 0.251306690929466 0.449428472264112 1.66447111884204 5.30704684079179 0.313634148854377 0.753920708929526 21.6428537916963 17.1352559491476 1.26305984899939 0.207115804440601 PTPRO other 1 1 1 0.313634148854377 1.26305984899939 1.61464607425131e-10 251.779054401343 43.4339933787795 5.79682029707991 1.15252315381111e-08 -235.37773239601 139.50200032485 -1.68727137853149 0.0921308193364339 EPS8 other 1.38036092887744e-06 1 0.000123089472827026 5.79682029707991 -1.68727137853149 1.20212377415022e-28 47.064125501422 22.5970455972839 2.0827556991379 0.0377682556943812 -337.661749750467 40.5262198702217 -8.33193302587242 7.31653712818915e-16 ACAD8 other 1.62382879412212e-24 1.10552876006938e-11 1 2.0827556991379 -8.33193302587242 1.71952462617962e-30 46.8340382161264 19.7210320083701 2.37482694598584 0.0179239403283214 -299.931699850415 35.3682907704957 -8.48024298931118 2.4092910565959e-16 THYN1 other 2.36314269375865e-26 3.6505578089541e-12 1 2.37482694598584 -8.48024298931118 2.82843160813963e-47 166.888515050615 35.778884736852 4.66444150727597 3.95097042243658e-06 -629.730760059595 64.4335426427712 -9.77333752314245 8.3222228976909e-21 VPS26B other 4.2477385891041e-43 1.28503443763245e-16 0.0366057409638749 4.66444150727597 -9.77333752314245 4.38248987363254e-17 210.600722946862 40.4809932873859 5.2024593727666 2.83810306174354e-07 -201.95962248209 72.967971732153 -2.76778451816411 0.00584587018650537 NCAPD3 essential 4.82775084479361e-13 1 0.00282561540827187 5.2024593727666 -2.76778451816411 7.69458948707617e-18 63.3923179467414 11.2693375629264 5.62520357498989 2.96005174460355e-08 -94.7366799653073 21.4252882008869 -4.42172254940242 1.18157061417405e-05 VTI1A other 8.65410479611456e-14 0.142001156411437 0.000310716631631035 5.62520357498989 -4.42172254940242 1.18088978993952e-11 176.139430019227 178.897332155359 0.984583883376543 0.325265397706793 -1989.54852162787 342.527785218681 -5.80842958581499 1.07265563687057e-08 QDPR other 1.0659892133784e-07 0.000146471127214676 1 0.984583883376543 -5.80842958581499 2.09320587995303e-07 73.0411397538266 26.5208045472436 2.75410723772398 0.00608399285557832 -177.674593537472 51.827897364657 -3.42816518847692 0.000654127076527185 FAM160B1 other 0.0014796872365388 1 1 2.75410723772398 -3.42816518847692 1.07993123656384e-05 -5.67889591910587 15.5332352791959 -0.365596465709354 0.714809909288115 -132.539341689774 28.9668435934782 -4.57555346898807 5.90239191490316e-06 TEX9 other 0.0654978294975971 0.0722334722545849 1 -0.365596465709354 -4.57555346898807 5.58925186218903e-16 122.231785347564 15.7312095903272 7.77001823322739 3.99231344172964e-14 -129.452378328676 51.8200371515993 -2.49811434812298 0.0127824151611213 QTRT2 other 5.95646570953485e-12 1 5.01873722759833e-10 7.77001823322739 -2.49811434812298 3.70374986009752e-20 19.633216326188 7.19285060327669 2.72954596293772 0.00654908693291745 -130.485478683529 16.6153530640846 -7.85330761135516 2.1984155042684e-14 MMAA other 4.39709183390778e-16 3.28267403097357e-10 1 2.72954596293772 -7.85330761135516 1.06380202524589e-10 64.9860693379401 26.5384704469482 2.44874961681951 0.0146528031104539 -317.419377410946 61.4462711692535 -5.16580373993103 3.3756480754366e-07 ZNF827 other 9.16146304141761e-07 0.0043707891280753 1 2.44874961681951 -5.16580373993103 0.0141161200184047 -1.36725400762979 37.5946747666415 -0.0363682892887526 0.971002113961769 -235.903430854499 86.1177689126331 -2.73931191939987 0.00635991547528294 EDNRA other 1 1 1 -0.0363682892887526 -2.73931191939987 0.995323575058762 -1.34964566601432 14.1581044309806 -0.0953267206492026 0.924090682764883 -0.637928824347567 32.6051365391644 -0.0195652860886292 0.984397383163579 NR3C2 other 1 1 1 -0.0953267206492026 -0.0195652860886292 0.869065333967516 -18.2175132200021 142.978907947295 -0.127413990507729 0.898660000538872 304.882524144727 624.504048168193 0.488199436078939 0.625606026192471 AKR1C2 other 1 1 1 -0.127413990507729 0.488199436078939 0.0111111621133863 10.2233273136075 10.357981423793 0.986999966047805 0.32408964804352 62.9333453762558 20.93808882708 3.00568719026837 0.00277436988043672 DPYSL4 other 1 1 1 0.986999966047805 3.00568719026837 0.00376317741865949 -2.24340328911667 1.64209118113803 -1.36618679576728 0.172463010030172 -10.9938665228414 3.27278336296401 -3.35917942117768 0.000838322663805886 VENTX other 1 1 1 -1.36618679576728 -3.35917942117768 0.395899558649162 54.1051552577447 39.9918535391796 1.35290441601409 0.176666281100137 32.0120883440693 79.7060933159707 0.401626613628735 0.688121655119747 ADAM8 other 1 1 1 1.35290441601409 0.401626613628735 0.307411446655272 -14.7534345413306 10.7359932297321 -1.37420304070914 0.169947678390586 21.3542279407361 45.9764872321652 0.464459753806433 0.642505241224564 ITIH2 other 1 1 1 -1.37420304070914 0.464459753806433 4.89759293278324e-38 90.1736263630981 6.44546700653486 13.9902393840002 3.50143641727763e-38 -8.64146346428799 27.6024700453994 -0.31306848445356 0.754349285040363 KIN essential 7.11081517910799e-34 1 5.27106238256974e-34 13.9902393840002 -0.31306848445356 1.52313561629582e-08 110.8798690196 18.3722656175824 6.03517668030484 2.93936945666901e-09 -1.30299723060875 63.3407076128767 -0.0205712452499325 0.983595221393731 PIGF other 0.000116474180578142 1 3.20979144668256e-05 6.03517668030484 -0.0205712452499325 7.02545543470886e-06 2.41467664987757 1.69050354203755 1.42837716090625 0.153762520052859 -17.8838522746092 4.26529387149925 -4.19287693026483 3.21952981897495e-05 ANKAR other 0.0432697800223719 0.375783520470756 1 1.42837716090625 -4.19287693026483 0.025779207612408 8.72565600605133 11.1484118799362 0.782681524509774 0.434157879505646 -65.1043138668422 28.3313501801346 -2.29796015554854 0.0219461048688171 INPP1 other 1 1 1 0.782681524509774 -2.29796015554854 3.83781244520334e-08 259.193388686987 76.9937418985691 3.36642150771742 0.000815808501803386 -747.955651800843 195.663443986405 -3.82266424714886 0.000147422170044242 MFSD6 other 0.000286415942785525 1 1 3.36642150771742 -3.82266424714886 0.000197188178007767 120.334855623881 29.0749090428534 4.1387870017588 4.04868773867596e-05 41.2913912563042 88.8367769572541 0.464800645302255 0.642261235372731 RNF144A other 1 1 0.346810591694982 4.1387870017588 0.464800645302255 8.7037040519642e-19 297.977657458253 33.4260210817026 8.91454165992154 7.57178363484533e-18 -120.442756752302 101.782717846948 -1.18333209507544 0.237199204250016 ASAP2 other 1.00110004005692e-14 1 1.01628479946894e-13 8.91454165992154 -1.18333209507544 5.79374134522126e-28 384.077185713312 32.7995659280503 11.7098252628047 2.21724998564713e-28 61.4924919400016 99.8811930716925 0.615656361812416 0.538380734418154 ADAM17 other 7.76940714394171e-24 1 3.23651980404912e-24 11.7098252628047 0.615656361812416 0.396079100435494 -8.24435832976764 20.364187996929 -0.404845915339758 0.685751095284861 -47.3337543680995 36.7168896992145 -1.28915479377089 0.197896218318053 FLI1 other 1 1 1 -0.404845915339758 -1.28915479377089 1.76462104294039e-07 -20.0561010783661 45.0066754636712 -0.445625029437136 0.656045741731155 -435.742529211906 87.9756295536458 -4.95299131614851 9.77419098357633e-07 TMEM45B other 0.00125464556153062 0.0124210419019288 1 -0.445625029437136 -4.95299131614851 5.3835715871141e-07 136.878100790039 41.8817762255163 3.26820190368733 0.00115091849407908 -225.654381709717 88.1619805235782 -2.55954301808553 0.0107511997281796 WWC2 other 0.00367644103684022 1 1 3.26820190368733 -2.55954301808553 4.19345003282458e-13 276.903397355236 35.8220529993443 7.72997006509662 5.21595609067285e-14 210.561368268967 75.0704182667897 2.80485140659083 0.00521366056346341 CENPU other 4.01732513144594e-09 1 6.53872255526749e-10 7.72997006509662 2.80485140659083 0.0016995691091187 1281.25952612711 371.298263911311 3.45075549944707 0.000602347244100407 454.360155860508 778.11051125588 0.583927538939379 0.559510658836808 ACSL1 other 1 1 1 3.45075549944707 0.583927538939379 0.0274446684571268 258.660406255202 96.1862894750707 2.68916087382954 0.00738215987864929 252.319383339833 201.320633902807 1.2533210255122 0.210625325489103 SLC25A4 other 1 1 1 2.68916087382954 1.2533210255122 7.50827351131108e-10 28.9898223284582 7.18927175341597 4.03237258553813 6.35389879864621e-05 -160.675671341192 35.5748535604638 -4.51655186909215 7.79378458668576e-06 AMN1 other 6.18831902802259e-06 0.0947412454357521 0.534871200870038 4.03237258553813 -4.51655186909215 3.12788999498742e-10 175.671863287385 26.0439141822768 6.7452174069492 4.15541963336193e-11 83.2843798902884 120.492885630108 0.691197488173342 0.489755935283147 BICD1 other 2.63274500878091e-06 1 4.83690845323329e-07 6.7452174069492 0.691197488173342 0.0036845569122174 97.5755866097653 34.8301378694905 2.80147000782436 0.00526815003124379 -79.5875297172723 82.7074614869701 -0.962277505395456 0.336337753671117 SAV1 other 1 1 1 2.80147000782436 -0.962277505395456 8.08953588377485e-27 16.5843875009225 3.52643502907013 4.7028762373925 3.25746116549752e-06 -44.8019036182143 6.7297977231001 -6.65724371840052 6.84043692663987e-11 CCDC122 other 1.07113544637063e-22 9.80254889800893e-07 0.0303367358342784 4.7028762373925 -6.65724371840052 8.09386463451129e-13 -6.560035237863 4.4335556381135 -1.47963300188882 0.139550058437505 -61.1008245449899 8.48944445644539 -7.19727007561734 2.05004811947523e-12 SERP2 other 7.66893674119944e-09 3.00291048540732e-08 1 -1.47963300188882 -7.19727007561734 4.30622638135687e-11 156.272649918569 31.8991708340347 4.89895648797976 1.27467774590961e-06 -344.821015709531 93.5658133877967 -3.68533124679173 0.000251407229616567 NBAS essential 3.78474236657455e-07 1 0.0121935673173713 4.89895648797976 -3.68533124679173 0.0232551378898927 -38.335562817824 38.5932239747946 -0.993323668498415 0.320999618245264 -233.262658479514 84.848513657599 -2.74916611292487 0.00617591423262258 ZNF385D other 1 1 1 -0.993323668498415 -2.74916611292487 0.00994273075670928 25.0546644695991 17.538965397666 1.42851439075952 0.153718798190332 118.990101051855 39.2118730819044 3.03454264485946 0.00252436707572195 TDO2 other 1 1 1 1.42851439075952 3.03454264485946 1.77376817901263e-14 134.321737304244 37.6102259335553 3.57141532575597 0.000386768786506815 -395.606639528376 79.431592322386 -4.9804697093663 8.54960161197639e-07 GUF1 other 1.79505339716078e-10 0.0108913374934967 1 3.57141532575597 -4.9804697093663 0.717658627635699 -5.24405651178248 6.63748094225207 -0.790067279651306 0.429835920833306 -7.41124732215409 14.0229664580735 -0.52850781211754 0.597364466906373 GABRA2 other 1 1 1 -0.790067279651306 -0.52850781211754 0.0420444505014445 55.2509089340853 27.9504785477626 1.97674286111671 0.04858376720663 132.685877287116 56.8409300873038 2.33433684289331 0.0199472527405581 SACS other 1 1 1 1.97674286111671 2.33433684289331 1.36443124064337e-20 4.49968775637827 1.60892014731348 2.79671291573525 0.00534520224852688 -27.2310874522675 3.44905716479748 -7.89522647818057 1.6083795581426e-14 CCDC175 other 1.63384831620467e-16 2.40517079124645e-10 1 2.79671291573525 -7.89522647818057 0.0655239394161168 259.085585415197 170.281083400519 1.52151713062455 0.128707955365172 835.557546102106 365.590408015999 2.2855018287721 0.0226651295284297 PABPC3 other 1 1 1 1.52151713062455 2.2855018287721 1.83922813462384e-15 68.3565737956029 8.52711414900227 8.01637841374518 6.63238406293061e-15 23.811196186248 18.3792972935315 1.29554442729583 0.195678934482152 CENPJ other 1.92677539383193e-11 1 8.46756473314351e-11 8.01637841374518 1.29554442729583 2.11379606786159e-10 23.0124965737211 7.19838138664783 3.19689876621522 0.0014715246725178 -187.49094465625 34.5156978136432 -5.43204850351134 8.4830600109709e-08 FBXO4 other 1.79862907414343e-06 0.00112570206345584 1 3.19689876621522 -5.43204850351134 2.16902660523252e-11 53.3798558767502 8.99825980718927 5.93224212464967 5.46293839739719e-09 -130.68724169349 42.164364853251 -3.09947136991947 0.00204383850344521 TMEM267 other 1.93412102388584e-07 1 5.9087141706248e-05 5.93224212464967 -3.09947136991947 0.575357478842687 4.42318844159504 94.8351943595229 0.0466407905996017 0.962817427628436 -458.576527500425 444.390059556242 -1.03192345922037 0.302587675840648 CCL28 other 1 1 1 0.0466407905996017 -1.03192345922037 0.0127209101323188 34.6666789028351 43.3408836205456 0.799860916688868 0.424163779370065 -248.724207686235 105.844615945738 -2.34989947730309 0.01915872357727 PARP8 other 1 1 1 0.799860916688868 -2.34989947730309 3.05911767799034e-05 54.6910084297672 965.724484654428 0.0566321029432506 0.954859170394028 -7931.14714407197 1867.66998907173 -4.24654633338833 2.55547958763678e-05 GFRA1 other 0.17730646061632 0.30042218032258 1 0.0566321029432506 -4.24654633338833 1.08127586517589e-17 440.087773718091 66.0812997457281 6.65979294310931 6.7422498144876e-11 -405.348191782865 123.475319120585 -3.28282765065791 0.00109395128771892 CACUL1 other 1.21048833106441e-13 1 7.80213148532505e-07 6.65979294310931 -3.28282765065791 0.45810625300951 -386.265518938611 335.956557185204 -1.14974841442274 0.250778055365386 -1078.9847148349 1368.40237162765 -0.788499594276129 0.43076523814025 DST other 1 1 1 -1.14974841442274 -0.788499594276129 0.234112383736124 3.00389602377796 2.77532876780605 1.08235682151365 0.279601508940684 -10.6080934792615 11.2379627803534 -0.943951647340118 0.34563784145388 BEND6 other 1 1 1 1.08235682151365 -0.943951647340118 2.51224882425489e-25 243.913097660082 34.5663029765564 7.05638372219063 5.26652109137727e-12 -344.48890946256 64.189906739519 -5.36671459674317 1.19205952527572e-07 TIAL1 other 3.25989407435315e-21 0.00157268413169625 6.29454600841412e-08 7.05638372219063 -5.36671459674317 0.000133664420550481 42.5549358505077 130.811694280901 0.325314461252421 0.74506909212384 -922.75511924933 242.918383896143 -3.79862200813853 0.000162032598030513 BAG3 other 0.715371978786172 1 1 0.325314461252421 -3.79862200813853 0.000493497429369245 42.6395728606668 12.1623279335793 3.50587264983558 0.000493028653259717 86.8085554676589 46.1538915943704 1.88085018335155 0.0605311561155922 SCHIP1 other 1 1 1 3.50587264983558 1.88085018335155 0.000663787688010306 -405.706327152427 245.576705823456 -1.65205541703165 0.0991013545870901 -2022.2829655706 533.50873742077 -3.79053391955164 0.000167161766115492 KCNE4 other 1 1 1 -1.65205541703165 -3.79053391955164 6.98639952227962e-05 19.6493081511907 7.50202782283671 2.61919958379477 0.00905998134338831 -43.7025835422448 16.1692189162702 -2.70282589211958 0.00709052796670553 AP1S3 other 0.387675309491296 1 1 2.61919958379477 -2.70282589211958 0.000188693041121214 107.34830559014 26.4935506913918 4.05186555930455 5.82126238606507e-05 256.461359135558 195.254452919268 1.31347252419179 0.189577466647781 RABGAP1L other 0.988562842434038 1 0.491663821127056 4.05186555930455 1.31347252419179 0.0163285402399287 -111.197008007382 46.5063290522155 -2.39100806865521 0.0171436221963924 -280.9893148896 129.11022508095 -2.17635214184952 0.0299615801662426 CCDC74B other 1 1 1 -2.39100806865521 -2.17635214184952 0.00421708283262494 94.768984626289 33.9459780923631 2.79175884602392 0.00542721406985854 -31.6099864681275 67.2571961135971 -0.469986682387687 0.638553573353084 TMEM56 other 1 1 1 2.79175884602392 -0.469986682387687 0.0113780910991453 -63.4170815287034 147.179913843414 -0.43088136059227 0.666726574703998 -1218.53127883559 408.598833556243 -2.98221918117117 0.00299086121356742 MZT2B other 1 1 1 -0.43088136059227 -2.98221918117117 0.363685422126946 -3.4919607772013 14.0453083932517 -0.248621153728392 0.803748193689298 -55.7641380415563 39.3290404455111 -1.41788707300946 0.156799451159497 TUBA3E other 1 1 1 -0.248621153728392 -1.41788707300946 0.240684355187513 1.06411700407769 1.78613108654249 0.595766465348049 0.551580403326241 -19.5019750932647 12.6768705872227 -1.53839032741418 0.124537853315777 ASTN1 other 1 1 1 0.595766465348049 -1.53839032741418 6.87285247246283e-15 620.14235824339 78.6319751836687 7.88664352885529 1.75177935622745e-14 -106.052265661517 221.18800584812 -0.479466620510782 0.631802276476573 FAM168B other 7.06941605317527e-11 1 2.21845337672645e-10 7.88664352885529 -0.479466620510782 0.00951187991585643 143.571002985066 47.8304924039345 3.00166265846881 0.00281068320246372 -47.3925240286135 289.497840969555 -0.163705967097688 0.870024559081106 PTPN14 other 1 1 1 3.00166265846881 -0.163705967097688 4.87288611428261e-05 318.981002916143 76.4660934864708 4.171535230482 3.52307957933694e-05 -36.3078933348492 173.622005688634 -0.209120342728687 0.834432866252805 MGAT5 other 0.275902811790681 1 0.303513305759878 4.171535230482 -0.209120342728687 0.0444312712130338 -18.7850511604511 8.32706805535591 -2.25590220178022 0.0244745730450041 -33.5320561699762 18.9718484389256 -1.76746384401725 0.0777132124684582 TMEM163 other 1 1 1 -2.25590220178022 -1.76746384401725 6.61134424434777e-06 45.2227870318205 10.1510242538031 4.45499743682295 1.01960374403629e-05 -38.8504165690506 32.3472370539659 -1.20104281253559 0.230259188241519 GPATCH11 other 0.0407919939876257 1 0.0918357092253482 4.45499743682295 -1.20104281253559 0.00330208177011575 412.154927580336 155.922146217878 2.64333795793453 0.00844646378348476 -435.635228600456 352.301037091553 -1.2365425665416 0.216791522275606 HSPB8 other 1 1 1 2.64333795793453 -1.2365425665416 1.88895054205957e-14 61.3832544974043 8.23671194543362 7.45239786264891 3.65508890434988e-13 -48.5826948465563 25.8695684659494 -1.87798628765311 0.0609206946138273 GEMIN6 essential 1.90972899802223e-10 1 4.49027671899383e-09 7.45239786264891 -1.87798628765311 0.0061731149351899 -10.4861553823289 5.50031417846343 -1.90646480220851 0.0571184884213666 -49.5565398194861 17.1407920558944 -2.89114643348377 0.00399235300117319 TMEM178A other 1 1 1 -1.90646480220851 -2.89114643348377 6.3428344976396e-27 138.61625705255 13.1351807271155 10.5530528991046 1.0008788789789e-23 4.30235683644332 26.0586409277128 0.165102886538793 0.868927041055491 RNF219 other 8.40869569352082e-23 1 1.42194862336532e-19 10.5530528991046 0.165102886538793 0.246185287969484 -3.5025690339449 3.67919809731053 -0.951992510679229 0.341529865415914 4.49653274122453 6.7894438637727 0.662282925000271 0.508074568275023 CYSLTR2 other 1 1 1 -0.951992510679229 0.662282925000271 2.76701870606751e-09 32.6667366755879 7.64981594987826 4.27026439454504 2.30692941963909e-05 -24.6560351912639 14.1491787370772 -1.74257712404565 0.0819767771546524 ARL11 other 2.21195475363037e-05 1 0.201833254924224 4.27026439454504 -1.74257712404565 8.24876620593524e-10 -6.33989677274908 44.3080526932415 -0.143086784170863 0.886275116464371 -572.685974932151 94.7324621529121 -6.04529811552614 2.78686816845571e-09 SETBP1 other 6.77966094465818e-06 3.86510746283122e-05 1 -0.143086784170863 -6.04529811552614 3.912946147839e-21 86.3967900284288 15.6493946370456 5.52077521413564 5.26579671983944e-08 -274.828235444787 43.3285394928532 -6.34289174436905 4.79753640550676e-10 ARL14EP other 4.74053425810695e-17 6.76788460724838e-06 0.000546273751716144 5.52077521413564 -6.34289174436905 2.18629893570814e-18 144.777410386854 36.8196004950363 3.93207445057346 9.5161784494689e-05 -478.025545915697 78.686868953114 -6.0750358004527 2.3386787377383e-09 EPG5 other 2.49259941660085e-14 3.24889250246604e-05 0.788225060969509 3.93207445057346 -6.0750358004527 2.92512148538306e-05 78.1613660462612 26.147694584805 2.98922590642781 0.00292398188644419 -97.1808269204252 53.9762669126355 -1.80043623761012 0.072348663943447 PSTPIP2 other 0.169832553441341 1 1 2.98922590642781 -1.80043623761012 2.24145615481187e-32 2135.43444833014 253.945689271088 8.40902026909603 3.6873974218944e-16 -2626.88082001719 524.216016863486 -5.01106554457162 7.34337172174534e-07 ATP5A1 essential 3.13377985004248e-28 0.00938556339756272 4.81352859454095e-12 8.40902026909603 -5.01106554457162 1.47587164773576e-17 124.718651567581 24.4688537170653 5.09703695194347 4.7767767244152e-07 -226.428030218544 50.5106626129119 -4.48277687334599 8.99922233252168e-06 HAUS1 essential 1.64648241021401e-13 0.108998580891503 0.00469175009872061 5.09703695194347 -4.48277687334599 2.78084013950949e-30 210.458088225783 24.419663897078 8.61838594965126 7.49772109197303e-17 -209.339776611799 50.4091208557827 -4.15281546390596 3.81543946932958e-05 C18orf25 other 3.81336608330936e-26 0.443315911941404 9.90973796726076e-13 8.61838594965126 -4.15281546390596 1.15308976921317e-12 66.8842936417098 8.8691024778079 7.54126968417226 1.9832214276056e-13 73.0624835275132 23.2203956185249 3.14647884247178 0.0017435997518639 SPC25 essential 1.08690241646033e-08 1 2.45344322809089e-09 7.54126968417226 3.14647884247178 7.98987625509634e-08 163.544047784004 29.3676290866979 5.56885430898068 4.04097344481726e-08 231.087067476247 72.2201225974325 3.1997601106878 0.00145588850618308 PDK1 other 0.000581742890133565 1 0.000421392710825544 5.56885430898068 3.1997601106878 0.110511349705892 82.7361596950248 40.199590013987 2.05813441545642 0.0400619516635822 40.3237573602442 91.060854388917 0.442822084537262 0.658073749262136 PDE3B other 1 1 1 2.05813441545642 0.442822084537262 0.0588086376159076 128.357949593388 55.2171045518878 2.3246048599446 0.0204609605226791 168.338234767753 199.709500466022 0.842915506648085 0.399646832751964 TCF7L1 other 1 1 1 2.3246048599446 0.842915506648085 0.137388945753865 95.6119033524803 188.183166178283 0.508078938696878 0.611604314509742 -1273.01808230185 689.3990940821 -1.84656187283914 0.0653546233007384 TGOLN2 other 1 1 1 0.508078938696878 -1.84656187283914 0.00275795188279531 1.87715938229088 4.72407131584123 0.397360508931397 0.691258067713534 -28.7514635654887 9.61908396707844 -2.98900224427724 0.00292585045699427 KCNK13 other 1 1 1 0.397360508931397 -2.98900224427724 2.46523128420304e-10 678.914049279588 100.038663080895 6.78651661638654 3.05140008467731e-11 -195.336906207136 930.521826438601 -0.2099218961416 0.833808400125014 UHMK1 other 2.08854394397682e-06 1 3.56861239903012e-07 6.78651661638654 -0.2099218961416 7.85307755599772e-09 370.191101881201 120.008336542154 3.08471155044438 0.00214121380877252 -1038.10426297747 273.668741649142 -3.79328766859453 0.000165365612241447 ATG10 other 6.11833272387783e-05 1 1 3.08471155044438 -3.79328766859453 3.89550559236416e-40 37.6283576929934 7.10944642262523 5.29272681108394 1.74948498055087e-07 -161.39882865534 15.6824958642721 -10.2916544695567 8.05256852981603e-23 POC5 other 5.70808434449121e-36 1.24959758445685e-18 0.00176138147841862 5.29272681108394 -10.2916544695567 0.0310330012887281 -108.105108352331 69.2245727929725 -1.56165800655263 0.11894903475778 -408.724903705799 160.479610389756 -2.54689616153187 0.0111423393913573 SPOCK1 other 1 1 1 -1.56165800655263 -2.54689616153187 8.06333124169255e-28 5.73221401167276 1.57642544674242 3.63621002408837 0.000302973531526682 -31.4690616376101 3.54118444670407 -8.88659207427042 9.21882293723106e-18 FAM151B other 1.07992195319988e-23 1.40835958012079e-13 1 3.63621002408837 -8.88659207427042 7.8598435551706e-27 73.4493532376966 6.35045038378829 11.5660069442006 8.94128381125725e-28 -30.2652635845597 52.7921051186246 -0.573291470695349 0.566687797263585 TADA1 other 1.04095768044679e-22 1 1.30113562021415e-23 11.5660069442006 -0.573291470695349 0.750467331110688 -38.0220977281029 64.1101205217709 -0.593074812816662 0.553378467708334 -90.4118210597977 124.283832615898 -0.727462447502868 0.467256823926993 GUCY1A2 other 1 1 1 -0.593074812816662 -0.727462447502868 7.96510116925401e-35 43.2642048663564 12.9142336848961 3.35011785615713 0.000864108651666269 -215.521133512838 24.6324762730451 -8.74947086617837 2.72552408973983e-17 CWF19L2 essential 1.13478796358362e-30 4.15369871276349e-13 1 3.35011785615713 -8.74947086617837 4.3469988472437e-07 73.3100812481273 24.788305965655 2.95744619861078 0.00323676143147643 -162.61954920016 54.719468775282 -2.97187733799088 0.00309078307541283 JMY other 0.00299464750586619 1 1 2.95744619861078 -2.97187733799088 0.00256356436749888 38.6162436807472 15.5704383014826 2.48009997747271 0.013436069197804 111.470351634255 34.3712924003727 3.24312366075145 0.00125476662756574 HOMER1 other 1 1 1 2.48009997747271 3.24312366075145 9.61807718331252e-11 22.6944701814772 4.70371269463412 4.82479939885921 1.82259611903161e-06 -28.6682128131003 10.6983924311228 -2.67967482008804 0.00759260695279096 XRCC4 other 8.29847699376204e-07 1 0.0172563400549912 4.82479939885921 -2.67967482008804 1.42263940728869e-54 37.9477242112583 2.21173637761636 17.1574354861204 4.28089719774126e-53 -18.2969345524642 11.1386890027771 -1.64264704292421 0.101031725692758 ZNF547 other 2.16767566488578e-50 1 6.58230753124696e-49 17.1574354861204 -1.64264704292421 1.69190031269945e-33 58.6365780819853 4.46608110509031 13.1293133067272 2.112825428721e-34 19.950701286269 22.4324663444555 0.889367267063799 0.374198837654701 ZNF773 other 2.38727134121892e-29 1 3.15212425710885e-30 13.1293133067272 0.889367267063799 8.01677811506422e-35 199.62852053493 15.473308287756 12.9014763244196 2.27050434550692e-33 -144.379682531392 78.0885317374363 -1.84892300212343 0.065017343576989 ZNF776 other 1.14190987470975e-30 1 3.37646701220334e-29 12.9014763244196 -1.84892300212343 1.89546776251703e-37 46.0734818684827 3.26422385488673 14.1146820551256 1.27121712659754e-38 35.0171629086839 16.147396775506 2.16859493796557 0.0305583569374316 ZNF256 other 2.7429313991384e-33 1 1.91648694005845e-34 14.1146820551256 2.16859493796557 1.06331941071044e-28 128.702968504887 10.8323397950208 11.8813636702983 4.17122355646633e-29 169.942419854389 42.4663024934568 4.00181814464712 7.1569814240501e-05 SUV39H2 other 1.43718251551623e-24 0.81568117289899 6.10583704195542e-25 11.8813636702983 4.00181814464712 2.32241835219834e-23 90.2924057761147 8.43611003541915 10.703085355338 2.16623987976909e-24 77.9398411758516 33.0723008520163 2.35665010198708 0.0187941424833028 DCLRE1C other 2.92555039826424e-19 1 3.09057443646656e-20 10.703085355338 2.35665010198708 1.69763039427284e-24 93.9941208414986 8.66232579559693 10.8509103743565 5.76431052178728e-25 -1.21410910185115 33.8531444751244 -0.0358639978848431 0.971403958757639 RPP38 other 2.17755050673377e-20 1 8.2567983914081e-21 10.8509103743565 -0.0358639978848431 3.53734828758134e-10 113.419686917101 17.1060434517776 6.63038692944015 8.08411004557582e-11 150.663912459221 66.8519487762901 2.25369514602177 0.0246126343907244 NMT2 other 2.96925015259578e-06 1 9.33714710264007e-07 6.63038692944015 2.25369514602177 0.00110967866894137 4.78448199813332 1.68091528345559 2.846355223981 0.00459263392210342 -13.5841275984357 7.67380727667584 -1.77019400001405 0.0772664258919304 ZSCAN1 other 1 1 1 2.846355223981 -1.77019400001405 0.000172648539955779 6.03677634076661 2.67226405719939 2.25904933477769 0.0243084713849863 -28.5429359296596 9.84796685009049 -2.89835824634171 0.0039152985439516 ZNF837 other 0.90847661724731 1 1 2.25904933477769 -2.89835824634171 7.75835671897431e-24 189.720156125144 22.5467511391012 8.41452300398731 3.66045922292869e-16 -106.456656686698 48.667270918646 -2.18743838882306 0.0291450472497957 USP12 other 9.84845801906599e-20 1 4.7787295155334e-12 8.41452300398731 -2.18743838882306 0.00214786265990625 104.369140690598 32.2235651955108 3.23890730455666 0.00127379419162736 186.632095828906 139.963397116928 1.3334350242513 0.182952329804642 CCDC50 other 1 1 1 3.23890730455666 1.3334350242513 0.33925434934045 -13.9642820108228 9.82809231604606 -1.42085376915149 0.155931151629298 -4.09196892069917 21.9119197180007 -0.186746253790698 0.851929082781962 CAMK4 other 1 1 1 -1.42085376915149 -0.186746253790698 0.00983037999776637 54.2476006488455 38.542540443482 1.40747340535046 0.159860281972151 -170.34074435479 86.1209003453753 -1.97792572617871 0.0484431223682393 TRIM36 other 1 1 1 1.40747340535046 -1.97792572617871 0.100350744457649 -358.140027490487 212.853208470849 -1.68256814197629 0.0930357209380107 -1106.79134434701 688.395814058393 -1.60778337366986 0.108466042560908 ZFP36L2 other 1 1 1 -1.68256814197629 -1.60778337366986 9.9574633116804e-29 230.578828098103 35.1994110320072 6.55064449483076 1.35985170329888e-10 -459.340898072647 76.0436176088346 -6.04049245047071 2.89822868263093e-09 PAN3 other 1.34624903973919e-24 4.01694495412647e-05 1.56029384436514e-06 6.55064449483076 -6.04049245047071 0.128454892243309 -2.43849757480872 16.0170982905179 -0.152243404553015 0.879051615689996 -104.652897327401 51.8073447872295 -2.02003977924763 0.0438707198535618 PLEKHH2 other 1 1 1 -0.152243404553015 -2.02003977924763 0.0627225623115373 170.443482846868 83.3681096735508 2.04446860453335 0.0413907851067973 413.054808095255 246.915976946004 1.67285573499192 0.0949338200459203 PFKM other 1 1 1 2.04446860453335 1.67285573499192 1.49313490588804e-16 2164.48292929787 402.284594561559 5.38047680313706 1.10713649961192e-07 -2258.99852927159 809.81727945984 -2.7895163348186 0.00546439690074228 TMEM123 other 1.61736373005792e-12 1 0.00112728638390486 5.38047680313706 -2.7895163348186 0.168909151766898 -8.76679005446194 8.41919627224645 -1.04128586280395 0.298206292404854 -31.1931309216551 16.5173797791943 -1.88850358462706 0.0594911254578642 GRIA4 other 1 1 1 -1.04128586280395 -1.88850358462706 0.469502756803303 5.975704367435 15.665140049608 0.381465109696515 0.703006284354278 85.769762383138 73.3679695488747 1.16903551932157 0.242898507828295 IGSF10 other 1 1 1 0.381465109696515 1.16903551932157 5.0713518272665e-07 13.368091078069 11.4296396019641 1.16959865259196 0.242676596618857 -283.544199502309 55.4922195685486 -5.10962080282357 4.48041720870486e-07 SPEF2 other 0.00347032605539846 0.00577615386546231 1 1.16959865259196 -5.10962080282357 1.91788023100706e-05 -1123.3828451529 341.654985695475 -3.28806220364714 0.00107347685522022 -3628.68698191548 835.64157036278 -4.34239644198187 1.67920737514833e-05 SPARCL1 other 0.113691940094098 0.200077558748923 1 -3.28806220364714 -4.34239644198187 0.000219767185606818 283.960942962539 68.6568357452534 4.13594567649691 4.09428459613093e-05 74.7398441120761 295.259538319076 0.253132699920799 0.800261298264207 MBNL1 other 1 1 0.350593589966691 4.13594567649691 0.253132699920799 0.0145904827341527 9.35479173703573 3.25234547208137 2.8763216630394 0.00418175439030836 -1.36831466090695 16.3335643184026 -0.0837731822787331 0.93326770179357 CAPSL other 1 1 1 2.8763216630394 -0.0837731822787331 3.4469555719843e-14 137.31310743471 19.5489598162273 7.02406208440457 6.48813261687824e-12 -294.826595836164 98.1765914037031 -3.003023344168 0.00279648664572781 NADK2 other 3.45247070089948e-10 1 7.73450289258055e-08 7.02406208440457 -3.003023344168 6.19638318222575e-17 49.7048155070743 95.4153639516226 0.52093094286446 0.602626462790004 -1584.87561316232 194.807081849558 -8.13561600592251 2.78799192833692e-15 GPD1L other 6.79185560603765e-13 4.1970430489184e-11 1 0.52093094286446 -8.13561600592251 0.0583916228257466 -745.84078837634 726.071917250825 -1.02722715292497 0.30478033314318 -5288.68055272724 2216.61308861108 -2.3859285952521 0.017384853722487 GJA1 other 1 1 1 -1.02722715292497 -2.3859285952521 3.46908595627542e-06 126.004879395057 36.4204680315175 3.45972707670905 0.000583453216539682 -166.560894093816 84.9624660001708 -1.96040559949709 0.0504621289851901 CCNO other 0.022004412220655 1 1 3.45972707670905 -1.96040559949709 0.456813856397051 3.2477145603268 2.86715546628168 1.13273054025865 0.257827344904621 6.79407297547649 9.51505260083236 0.714034200387096 0.4755128392813 CLEC4F other 1 1 1 1.13273054025865 0.714034200387096 3.71747964194838e-12 160.532551788896 23.2553516618026 6.90303694923583 1.42030593910501e-11 -84.7589715679853 72.9875495857867 -1.16127986278486 0.246036466598661 SLC30A6 other 3.43346419730352e-08 1 1.67780740586475e-07 6.90303694923583 -1.16127986278486 9.21794931865434e-16 65.4492279078246 10.6313727940891 6.15623486970691 1.48666091362104e-09 -80.8065812435441 25.4967136818988 -3.16929398242065 0.00161769654310459 PELO essential 9.75812114872748e-12 1 1.64246297736853e-05 6.15623486970691 -3.16929398242065 0.311107886783611 7.95831135961417 18.0047650077517 0.44201139843746 0.658656618880978 85.2654141237179 55.8495456863057 1.52669843730931 0.127417193161697 RASGRP3 other 1 1 1 0.44201139843746 1.52669843730931 3.97695203631886e-37 229.374821411561 48.4814837879722 4.73118402099045 2.84638135264478e-06 -1166.62844080389 111.802447053297 -10.4347308270252 2.28899660010891e-23 SAR1B other 5.74391182605533e-33 3.55458282030912e-19 0.0266392830794025 4.73118402099045 -10.4347308270252 2.67937220886237e-16 1.98992910609726 0.884886436048504 2.24879603193305 0.0249248219291872 -14.4605730363746 2.05040752681227 -7.05253606772318 5.35969495878294e-12 CATSPER3 other 2.88407624561946e-12 7.81121943293026e-08 1 2.24879603193305 -7.05253606772318 3.22927953421845e-39 235.512544005334 16.2526802483408 14.4906895605343 2.11301454342906e-40 191.808072229576 40.6600868012276 4.7173552080018 3.05058341048217e-06 GPR180 other 4.71184176837814e-35 0.0378729930411362 3.19572319548211e-36 14.4906895605343 4.7173552080018 2.05813673462913e-08 2.40265089588648 9.89309678186914 0.242861355636363 0.808204851673817 -112.805450695431 20.0798895008475 -5.6178322440803 3.0972968381731e-08 WDR78 other 0.000156356647729775 0.000416834208481336 1 0.242861355636363 -5.6178322440803 0.000138667983310278 53.2089748135494 13.2134008857041 4.02689476190173 6.46598073349714e-05 71.8023294273123 26.8516440926095 2.67403847524832 0.00772264299020789 ANKRD22 other 0.739932358943642 1 0.543918299301779 4.02689476190173 2.67403847524832 1.14378655652303e-36 1935.92330150266 159.558118345861 12.1330291530909 4.25737011675632e-30 -955.1068322513 393.098069878789 -2.42969097392365 0.0154397156076617 FARP1 other 1.64728139870447e-32 1 6.26088849370184e-26 12.1330291530909 -2.42969097392365 4.80189390292728e-07 178.643727362266 38.5443540456844 4.63475732789631 4.49295264258027e-06 -58.954236857942 74.5034649455605 -0.791295235745341 0.42912173634825 IFIT5 other 0.00329265864923723 1 0.0414609669857307 4.63475732789631 -0.791295235745341 0.01056674593099 -6.83862578079726 4.65272685999043 -1.46981028256865 0.142199855183301 -27.1292104788464 8.99338647895635 -3.01657340561601 0.00267782628267749 SLC16A12 other 1 1 1 -1.46981028256865 -3.01657340561601 0.00445648314070712 37.3980215140363 11.3439699070906 3.29673137537682 0.00104320951128574 34.5243827628227 21.9993677152676 1.5693352286149 0.117162177167142 PANK1 other 1 1 1 3.29673137537682 1.5693352286149 0.110587786988187 -2.37666663516907 1.74947370723946 -1.35850377478337 0.174877481202494 -8.03504255458969 4.00277149345794 -2.00736978559032 0.0452136762635175 PRDM8 other 1 1 1 -1.35850377478337 -2.00736978559032 6.81731387570714e-11 205.736080351135 86.6367710031798 2.37469700184907 0.01791113353418 -1041.64033921106 200.388559531268 -5.1981028340519 2.85866654868602e-07 HNRNPDL other 5.93242653464035e-07 0.00371112091350419 1 2.37469700184907 -5.1981028340519 0.0182657635037451 -47.3796706369429 20.9782035333295 -2.25851897001893 0.0243085693013262 -97.7799782852559 39.8813687904164 -2.45177087073181 0.0145288183071833 HHEX other 1 1 1 -2.25851897001893 -2.45177087073181 0.00705767271446488 -75.565030961988 115.613997398732 -0.653597597714555 0.5136498166561 -770.027251619277 253.397428258998 -3.03881241774968 0.00249032045207961 UTRN other 1 1 1 -0.653597597714555 -3.03881241774968 7.71173159619308e-13 735.821110995842 130.981083275443 5.61776626513671 3.09582053491909e-08 -642.509381306296 312.339205620142 -2.0570884786321 0.0401556625900815 PTPRK other 7.3130350726699e-09 1 0.000324565824880918 5.61776626513671 -2.0570884786321 6.38142339696465e-33 293.369877196596 22.8663677673805 12.8297541691382 4.25357226927524e-33 -256.120333510715 145.279127878505 -1.76295340735322 0.078470803568642 GGPS1 essential 8.96845244209412e-29 1 6.31953232046222e-29 12.8297541691382 -1.76295340735322 0.000130240944398761 99.7138663947019 37.4928150797156 2.65954600055223 0.00806786086248573 -406.343471645479 151.15078990116 -2.68833177723512 0.00741310967890602 ZNF117 other 0.698091461977359 1 1 2.65954600055223 -2.68833177723512 0.0810856573016544 -14.3242471263349 15.2066687122351 -0.941971407242523 0.346630839957052 51.7325885225899 35.0330608466869 1.47667909318527 0.140347844879666 PART1 other 1 1 1 -0.941971407242523 1.47667909318527 0.167096265670949 7.08913118424465 9.865963231882 0.718544253371634 0.472733709453566 -29.6038513308676 22.70388262757 -1.30391139773242 0.192821412129541 RAB3C other 1 1 1 0.718544253371634 -1.30391139773242 2.21577659326719e-28 104.451714182119 28.2337305459972 3.69953641131309 0.00023841699883449 -545.936565707304 61.6769404652697 -8.85155070256315 1.27552435829608e-17 MARVELD2 other 2.98531580410889e-24 1.94683282806731e-13 1 3.69953641131309 -8.85155070256315 7.81322819322626e-31 94.1920631552764 17.5272850535107 5.37402472018391 1.15203515433425e-07 -307.787403331894 37.8885488106308 -8.12349411613078 3.16089342806047e-15 RAD17 essential 1.07705350643624e-26 4.75619634120258e-11 0.00117161975195793 5.37402472018391 -8.12349411613078 3.60318606119738e-38 155.544045872574 11.7328403967624 13.2571517733673 6.28715650740788e-35 -183.978333650759 65.3425437081996 -2.81559797354005 0.00504652822150535 MED21 essential 5.23398807249532e-34 1 9.39112567511515e-31 13.2571517733673 -2.81559797354005 1.23739508521292e-16 902.469713921969 102.014689675421 8.8464682566143 1.26844230856987e-17 106.350340634173 371.809888521596 0.286034190906129 0.774961022937796 PLOD2 other 1.34467723910088e-12 1 1.6956536780962e-13 8.8464682566143 0.286034190906129 2.4155424357255e-12 -126.685103878586 37.4816028246946 -3.37992759997767 0.000776767056062887 -542.090034248903 72.4006239508717 -7.48736688535646 2.83136387903657e-13 STK32B other 2.24887000766044e-08 4.18362326766444e-09 1 -3.37992759997767 -7.48736688535646 0.147938243110683 9.03496684971871 4.68833575424843 1.92711600092453 0.0544846594664398 5.84591736798053 9.05920361799001 0.645301465172011 0.519003406404749 JAKMIP1 other 1 1 1 1.92711600092453 0.645301465172011 1.63954196149926e-05 58.6550046556486 13.5763788764753 4.32037181558657 1.85260083102932e-05 117.830263454959 52.459358488296 2.2461247497193 0.0250972281322203 ZIC1 other 0.0977986780034307 1 0.163232659221993 4.32037181558657 2.2461247497193 3.97159232753513e-06 157.628478651593 44.9761835082737 3.50470996772315 0.00049499388443343 401.647782799739 82.0481735163912 4.89526781140959 1.29778536495502e-06 ADGRA3 other 0.0250567759944192 0.0163962203008417 1 3.50470996772315 4.89526781140959 0.354441097069692 -2790.97888873994 10346.29917163 -0.269756252205902 0.787450263794874 -57668.0397691436 40327.1452702676 -1.43000550578672 0.153290562054829 CPB1 other 1 1 1 -0.269756252205902 -1.43000550578672 4.30183594015107e-29 41.8399714240695 13.2577681545298 3.15588347423121 0.00168934173079315 -273.640826113021 29.2548768565413 -9.35368237763872 2.24269757959608e-19 SREK1IP1 other 5.84017247234909e-25 3.4452320217755e-15 1 3.15588347423121 -9.35368237763872 0.0452495663468439 -4.3976013942634 9.14810992479311 -0.48071147268848 0.630915912145184 30.9507340126254 16.580960608784 1.86664299752505 0.0624921940082737 LGI2 other 1 1 1 -0.48071147268848 1.86664299752505 6.94773452988404e-19 72.0384309707826 10.5079068488357 6.85564042459745 1.94587606586997e-11 -72.5970361455909 23.1869736519464 -3.13094055461166 0.00183677648769983 CWC27 other 8.00517972533239e-15 1 2.28791663173324e-07 6.85564042459745 -3.13094055461166 6.84672356477832e-05 101.511215285025 23.4450395749498 4.32975235381925 1.77850857266899e-05 -112.427436876516 164.918187002281 -0.681716425096046 0.495709470950247 MR1 other 0.380540895730379 1 0.156882241195132 4.32975235381925 -0.681716425096046 7.51366222739086e-20 97.1335562278115 17.6840911697735 5.49270840640298 6.08516898041412e-08 -215.427875371581 39.5475002444546 -5.44731965459154 7.75683629986875e-08 SRP19 essential 8.87138099188038e-16 0.00103088354425256 0.000629389027644232 5.49270840640298 -5.44731965459154 0.000219084762219154 41.8887085264443 10.4449841641839 4.01041378981516 6.921828660003e-05 57.3525490696856 22.4911118854606 2.55000950427716 0.0110491141772555 CENPH essential 1 1 0.580326114854651 4.01041378981516 2.55000950427716 1.63885196354565e-22 200.080516614144 19.9385827218994 10.0348414631491 7.85954019168681e-22 10.2573207487341 61.2598959496091 0.167439408600556 0.86708747164867 CDYL other 2.03824018706172e-18 1 1.09813495558248e-17 10.0348414631491 0.167439408600556 2.4463053150055e-17 333.27053969452 36.9776176849601 9.01276395180187 3.46988502830122e-18 332.842154965284 182.733237161301 1.82146477639139 0.0690893635957867 CARHSP1 other 2.7134418554041e-13 1 4.67497609863023e-14 9.01276395180187 1.82146477639139 0.902594611044354 3.09218947790959 13.3659286778782 0.231348644185678 0.817131108331427 -7.80506796057135 29.3747676307259 -0.265706543067502 0.790566073274261 BANK1 other 1 1 1 0.231348644185678 -0.265706543067502 8.36957235504398e-28 239.22575566869 24.168410915253 9.89828236980661 2.45551399422211e-21 -411.087714137997 125.49270651632 -3.27578968969433 0.00112141139685028 TXNDC11 other 1.12060204261684e-23 1 3.41635662016122e-17 9.89828236980661 -3.27578968969433 0.173010663944934 -121.528317999157 64.8523235425276 -1.87392388369035 0.0614806824762264 -130.045740520502 304.479972098129 -0.427107699808217 0.669471126850462 DAB2 other 1 1 1 -1.87392388369035 -0.427107699808217 0.14968979340147 -0.0796726473986548 7.41231500934532 -0.0107486861119913 0.991427902289009 -31.1883411196013 16.8879288321916 -1.84678307384565 0.0653224890623432 ACMSD other 1 1 1 -0.0107486861119913 -1.84678307384565 0.00179230912498437 1.08267966432292 41.2222147418235 0.0262644710165086 0.979056007104252 -413.94770187645 118.761336623387 -3.48554263235643 0.000530700480243142 BCL2L11 other 1 1 1 0.0262644710165086 -3.48554263235643 6.4847921246632e-07 120.688024828155 26.5985604786036 4.53738934199987 7.01414712551042e-06 -130.995973452659 71.3918833188148 -1.83488608736753 0.0670684236785615 ANAPC1 essential 0.00440252537343385 1 0.063926936901902 4.53738934199987 -1.83488608736753 4.79431345407563e-14 731.931809836792 185.279143772169 3.95042741959571 8.82616017831857e-05 -2089.7487463382 430.060126534251 -4.85920134744639 1.54308240005763e-06 CAST other 4.77130074949607e-10 0.0194243212519254 0.732747818004008 3.95042741959571 -4.85920134744639 4.06649748911434e-27 448.881247275912 56.2903161221614 7.97439556569105 9.1924769502537e-15 -621.969375130027 124.841549623938 -4.98207028832624 8.48225720405104e-07 SCOC other 5.40518846253078e-23 0.0108089403551222 1.17112156346232e-10 7.97439556569105 -4.98207028832624 5.21862284090692e-05 31.9316855350703 54.0130113338688 0.591185063496868 0.554643346123407 -472.468631073583 120.783595511465 -3.91169536784269 0.000103319273370253 CLGN other 0.294017210856696 1 1 0.591185063496868 -3.91169536784269 3.80873808013719e-27 62.2979828202596 10.0192349028234 6.21783833042026 1.00610692829711e-09 -147.793395036239 22.3598739941223 -6.60975974529593 9.21242606461836e-11 CETN3 other 5.06371727754239e-23 1.3179296728043e-06 1.12080311812298e-05 6.21783833042026 -6.60975974529593 3.89559927201417e-25 728.370600095873 81.1068903210281 8.98037882124341 4.61501112929053e-18 -583.073379129981 186.02019174607 -3.13446284329132 0.00181632853606835 SMARCA5 other 5.03934721827753e-21 1 6.20811297112162e-14 8.98037882124341 -3.13446284329132 0.000421674100991045 10.6790632214497 2.83707835522291 3.76410584564579 0.000185571711390771 -1.65710646574585 9.75765781956813 -0.169826253019722 0.86521073758119 SYCP2L other 1 1 1 3.76410584564579 -0.169826253019722 0.0429108600030171 27.9547357304923 11.1095380007313 2.51628247085092 0.0121482541120499 28.6281656673411 34.6463827179607 0.826295948422352 0.409000488203434 BMP6 other 1 1 1 2.51628247085092 0.826295948422352 0.113598351323795 4.12011878305738 6.19541264061536 0.66502733910685 0.506314317212223 -35.552487555412 19.5165077151986 -1.82166236266365 0.0690542375823103 RGPD3 other 1 1 1 0.66502733910685 -1.82166236266365 1.89921456014922e-37 529.697426757527 37.5256076428467 14.1156255695836 1.44956789256291e-38 450.355331848806 157.316980016654 2.86272550999345 0.00436856659778352 RASSF3 other 2.74816346853592e-33 1 2.18478872767082e-34 14.1156255695836 2.86272550999345 5.02250706933828e-15 1212.54562735873 145.433523320645 8.33745617704225 6.26845665773307e-16 -267.761876311075 912.170058539298 -0.293543812148203 0.769218674796797 HNRNPU essential 5.18674305050564e-11 1 8.14899365505299e-12 8.33745617704225 -0.293543812148203 0.000332456359446796 177.180137673469 91.4806181146911 1.93680520885128 0.0532875650031488 -1038.19486964236 328.199129509775 -3.16330781008801 0.0016471211001617 RANBP2 other 1 1 1 1.93680520885128 -3.16330781008801 3.56143517774575e-23 286.835626739197 26.8814639164962 10.6703871348009 3.05455387354892e-24 147.77402807846 171.750900665134 0.860397398244671 0.38995327299091 AHCTF1 essential 4.47529944435531e-19 1 4.35396109135663e-20 10.6703871348009 0.860397398244671 0.791339007533904 7.77583517585687 11.8200721429148 0.657850060629106 0.510912751908408 -0.935184328358351 30.8400114136948 -0.03032373483309 0.975819989112331 MERTK other 1 1 1 0.657850060629106 -0.03032373483309 7.07555677681018e-10 -13.0917540726439 60.9028660873452 -0.214961214696663 0.829878118312114 -1030.39793975155 158.903013666149 -6.48444554938642 2.00150679727563e-10 TMEM87B other 5.83945700790144e-06 2.84614266572594e-06 1 -0.214961214696663 -6.48444554938642 1.24081786977882e-26 15.1335487243309 1.30882490694142 11.562699215204 9.55270138305562e-28 12.4263917660827 9.32459836696795 1.33264632717081 0.183217307130264 PTPRR other 1.63862407882991e-22 1 1.38972699720693e-23 11.562699215204 1.33264632717081 0.00178402725551858 -111.929621229541 72.8864810581058 -1.53567053319955 0.125203807024866 -636.587401863303 179.384101197591 -3.54873925622932 0.000420746945984619 NR4A2 other 1 1 1 -1.53567053319955 -3.54873925622932 1.07976610545968e-06 -2.04730523068689 2.05937032063835 -0.994141369412509 0.320596844042588 -26.966492121876 5.12227711487201 -5.26455158850768 2.02762905984588e-07 CCDC148 other 0.00718152436741233 0.00264585316019289 1 -0.994141369412509 -5.26455158850768 0.000349428770264182 -23.6303555906834 29.3832277803438 -0.804212381544114 0.421624979328512 -293.930937492285 73.590681596469 -3.99413256020704 7.38452182821641e-05 PLA2R1 other 1 0.840653964924156 1 -0.804212381544114 -3.99413256020704 0.31732701036997 1.01733458897411 3.75388201305847 0.271008674602759 0.786487729703768 -12.6147865949266 9.34804440995986 -1.34945728129898 0.17775456727946 SCN3A other 1 1 1 0.271008674602759 -1.34945728129898 0.207013993348813 0.708652503881088 9.73493692872245 0.0727947709440462 0.941996336707464 58.5227565380418 33.0799432421642 1.76913110490008 0.0774353491511648 CD96 other 1 1 1 0.0727947709440462 1.76913110490008 9.49996938607847e-12 26.2369349605542 3.70356300916052 7.08424155216447 4.54811287889751e-12 2.6509804494704 17.1758849532535 0.154343165239253 0.877398818517077 SLC25A27 other 8.619322223989e-08 1 5.44636517247977e-08 7.08424155216447 0.154343165239253 0.49090169841698 2.89174899163247 6.88440882679828 0.420043182266579 0.67461975813274 -31.4475665178058 32.4002143798247 -0.970597482755788 0.332180101852974 ADGRF1 other 1 1 1 0.420043182266579 -0.970597482755788 0.0109938288182897 7.44661911611851 2.95681995812885 2.51845537488556 0.0120739047216097 31.2287353973688 13.9790081593793 2.23397361538956 0.0258918833531565 ADGRF4 other 1 1 1 2.51845537488556 2.23397361538956 1.96353214441914e-62 474.97845567722 24.4941825154784 19.3914802168666 1.11253927552552e-63 250.466156054533 255.364145463635 0.980819588434354 0.327130063705776 FAM49B other 3.02423220883436e-58 1 1.72198829065839e-59 19.3914802168666 0.980819588434354 1.09160204277621e-19 190.388576405077 19.5500820282705 9.73850524666674 9.91613530873916e-21 103.712966954818 200.599216227741 0.517015813447011 0.605360396807696 ASAP1 other 1.28503392475616e-15 1 1.37269061078876e-16 9.73850524666674 0.517015813447011 6.23380694584668e-38 338.727064996652 30.0679348618962 11.2653917388223 1.35413524179114e-26 -355.848232448595 78.8674169073322 -4.51198031332395 7.88077618021613e-06 TRAPPC8 essential 9.04400711703436e-34 0.0957750729181667 1.95780873258162e-22 11.2653917388223 -4.51198031332395 3.86916144808557e-05 0.813810720613121 2.7202593855342 0.299166588649893 0.76492719710153 -25.5819708614528 6.30181935950317 -4.05945797587407 5.64059598913005e-05 FAM81B other 0.221935100662188 0.648048073191151 1 0.299166588649893 -4.05945797587407 5.73639664351798e-30 74.9469594443195 7.58507381647996 9.88084773565202 2.80772984993076e-21 -51.4141897694767 16.4703325318615 -3.12162427018501 0.00189464010672253 INO80C other 7.84452241001084e-26 1 3.90442912931371e-17 9.88084773565202 -3.12162427018501 2.43756245289814e-15 667.073133202743 78.891524506385 8.45557412379266 2.73954736023186e-16 257.396802474576 362.095470885721 0.710853416213571 0.477489553970519 LPCAT1 other 2.54408393208979e-11 1 3.5836019019193e-12 8.45557412379266 0.710853416213571 1.90810947221408e-07 138.731701595725 32.4567556289368 4.27435518145379 2.27992032378732e-05 626.987583433475 141.295604703919 4.43741746070099 1.11168592671371e-05 PLEKHG4B other 0.0013520863720109 0.133846985576331 0.199675421957294 4.27435518145379 4.43741746070099 4.87414175103674e-25 311.16054985845 29.8515141202201 10.4236102934452 2.563992991473e-23 -158.707641243633 150.046108180276 -1.05772580954216 0.290649919491558 NMRAL1 other 6.29982821321498e-21 1 3.63112687452406e-19 10.4236102934452 -1.05772580954216 2.91400819693806e-16 101.031888152645 13.5053135289445 7.48089912434195 2.98202759400011e-13 -159.63357892423 67.9213777679086 -2.35027003530034 0.019116042729202 UBALD1 other 3.13226741088872e-12 1 3.67355979304874e-09 7.48089912434195 -2.35027003530034 0.00493883839529595 111.760615385386 40.1306229750307 2.78492101791999 0.00554096502610005 -149.462253751331 195.550802676299 -0.764314192045229 0.44501203221218 C16orf89 other 1 1 1 2.78492101791999 -0.764314192045229 2.76468882885385e-33 68.008828575675 10.035242890769 6.77699875488149 3.18805487259858e-11 -152.414747436539 20.2682876924363 -7.51986303674862 2.26669423311772e-13 TMEM251 other 3.89544655985508e-29 3.35312077905104e-09 3.72587972960596e-07 6.77699875488149 -7.51986303674862 0.0197909357142265 85.603337546325 30.4972163829622 2.806922981802 0.00518007314537642 75.1175891783524 87.7913225778459 0.855637971642863 0.392572693015587 ING1 other 1 1 1 2.806922981802 0.855637971642863 6.22056656531909e-08 25.7905573262146 10.4148810346626 2.47631799541242 0.0135792975996569 -134.8095821353 29.8500024608215 -4.51623353506383 7.73271744835719e-06 ADPRHL1 other 0.0004571494368853 0.0940066460196784 1 2.47631799541242 -4.51623353506383 0.0481472661803778 79.1652000173994 47.1809780073671 1.67790502361011 0.0939389505981614 221.246819856811 96.3281830490471 2.29680258522222 0.0220083561934888 CMTM7 other 1 1 1 1.67790502361011 2.29680258522222 2.16044894402172e-14 16.8594629004971 11.3546755483085 1.48480357970322 0.138172947803954 -159.302930935836 23.1260240954753 -6.88847033446636 1.55792866040193e-11 FBXL2 other 2.1779485804683e-10 2.25603649312803e-07 1 1.48480357970322 -6.88847033446636 2.44751847249087e-14 322.560234797026 73.773867251923 4.37228312426062 1.47311020739954e-05 -715.401368775702 150.365900135444 -4.75773674836713 2.51064220025014e-06 UBP1 other 2.46367209440931e-10 0.0313177508059202 0.130900573029523 4.37228312426062 -4.75773674836713 0.00018529615041411 240.367339601967 58.3799687664125 4.11729133606966 4.431427603003e-05 -1.07225172314238 209.981377079278 -0.00510641342607044 0.99592756816571 RMND5A other 0.971693012771592 1 0.378178031640276 4.11729133606966 -0.00510641342607044 0.85702622465785 1.29679782843521 19.6383178148937 0.066034058551172 0.94737510435861 39.1813211174596 70.6249684008166 0.554780016255648 0.579274421569686 CD8A other 1 1 1 0.066034058551172 0.554780016255648 8.5799441376823e-15 108.162459098325 13.3640546716028 8.09353611282053 3.97628071424537e-15 -23.0229841722061 56.2335656873153 -0.409417113974678 0.682398678842103 RPIA other 8.79015276905552e-11 1 5.09520610723401e-11 8.09353611282053 -0.409417113974678 0.0838119669330286 32.6432939259361 15.7526612983239 2.07223994141292 0.0387153253797679 -1.54439120354448 38.7164233191536 -0.0398898211958656 0.968195654989171 PTPRD other 1 1 1 2.07223994141292 -0.0398898211958656 0.00735776661408358 -46.1552962533218 84.2476784814455 -0.547852440390828 0.584020447340087 -627.517973903233 202.151303322624 -3.10419949606629 0.0020083185098577 LURAP1L other 1 1 1 -0.547852440390828 -3.10419949606629 0.026881931433836 2.59183010238644 54.1768844810242 0.0478401467196632 0.961861230810779 -272.552201842881 116.709360789093 -2.33530712532488 0.0198906750394464 CNKSR3 other 1 1 1 0.0478401467196632 -2.33530712532488 6.22943445817505e-14 87.4577528558822 11.7199071043244 7.46232475030557 3.39746185512032e-13 -61.2891998169781 37.7322623889546 -1.62431818122094 0.104888214235311 GTF2E1 essential 6.17773015217220e-10 1 4.17683960468492e-09 7.46232475030557 -1.62431818122094 2.73079982716023e-49 284.144556194555 33.8468788505344 8.39500024357694 4.02360485445446e-16 -483.874748431683 74.2099061657527 -6.52035251669658 1.59916887743245e-10 CFDP1 essential 4.1210500191675e-45 2.27673673080059e-06 5.24678073020861e-12 8.39500024357694 -6.52035251669658 2.34611488477474e-24 197.526583410569 34.5722163135479 5.71344867274717 1.81838867433788e-08 -289.462247122252 74.2660811328907 -3.8976372888761 0.000109165504095661 ZDHHC7 other 3.00279244102319e-20 1 0.000192658280046099 5.71344867274717 -3.8976372888761 1.02332586575926e-15 21.1965141369841 2.5263998323199 8.39000773583814 4.28687404239564e-16 -2.98933568160907 13.7154827508832 -0.217953369626495 0.827547931584004 C7orf31 other 1.08206477045384e-11 1 5.58794031426272e-12 8.39000773583814 -0.217953369626495 0.089166777857918 22.5045745625771 10.6481935248661 2.11346408290039 0.0350199472332944 -8.03929303405854 43.0881422560918 -0.186577852121762 0.852061835304947 JAZF1 other 1 1 1 2.11346408290039 -0.186577852121762 7.47130697442237e-23 324.095444722581 49.4365764840325 6.55578253537157 1.28196944525001e-10 -284.198636418081 105.51674367606 -2.6933984741851 0.00728981054137175 CMIP other 9.34137511012029e-19 1 1.47234190786963e-06 6.55578253537157 -2.6933984741851 0.0816079975645819 10.294909301514 4.83944928264673 2.12728942907397 0.0338485868562628 12.8443494022322 9.97110332466724 1.28815728651181 0.198242906852935 SPHKAP other 1 1 1 2.12728942907397 1.28815728651181 0.0288614318396144 26.8224752607419 10.2258566661899 2.62300520497475 0.00897010141614887 32.1426152560912 34.6543181611385 0.927521214142256 0.354083817800804 KCNJ16 other 1 1 1 2.62300520497475 0.927521214142256 0.226789355487568 17.2689116324109 12.8694218553064 1.34185605434097 0.180205585007693 37.6068671017902 26.2929400540216 1.43030285029072 0.153207401405057 PID1 other 1 1 1 1.34185605434097 1.43030285029072 5.80951000933934e-12 605.174108074612 140.731295999121 4.30020987000925 2.02331780935015e-05 -1285.3925466345 292.34586430328 -4.39682138038058 1.32204623289924e-05 TRIP12 other 5.32906353156698e-08 0.158539784249277 0.177728236373317 4.30020987000925 -4.39682138038058 3.32121672684e-19 -9.84747586746694 10.7269129308548 -0.918015829059423 0.359018154334186 -209.077582833292 22.2833777647893 -9.38267012479868 1.74177818252156e-19 FBXO36 other 3.86124656662418e-15 2.67763559999039e-15 1 -0.918015829059423 -9.38267012479868 9.59866666110231e-26 435.721297195258 38.6547126832501 11.2721390730726 1.43180794868454e-26 210.346514136027 173.407254034882 1.21302027015383 0.225661414120616 CEBPG other 1.2530099459403e-21 1 2.06982157061837e-22 11.2721390730726 1.21302027015383 1.78744211821339e-13 193.698749091281 24.6015581228955 7.87343419972307 1.88651392035068e-14 197.717874879125 110.714183473456 1.78584051903819 0.0746830155688352 KCTD15 other 1.7415048557753e-09 1 2.38662876063564e-10 7.87343419972307 1.78584051903819 2.25942512605425e-14 21.0601677327087 3.53956896032762 5.94992440287402 4.80211789137317e-09 -65.3470620713254 15.9078206136487 -4.10785761660264 4.60701452158928e-05 ZNF599 other 2.27569298696184e-10 0.532939439857448 5.20357494709197e-05 5.94992440287402 -4.10785761660264 0.00149256191243765 21.1828939451425 6.19053594457172 3.42181906943244 0.000668982943297355 4.10436461992256 11.7465738187014 0.349409511511188 0.726917606361932 MCOLN2 other 1 1 1 3.42181906943244 0.349409511511188 0.656584499643669 -0.959476628103224 3.30212770233012 -0.290563150367013 0.771495775163335 -16.0560623783597 17.6752796589519 -0.908390853676136 0.364072525904903 LGI4 other 1 1 1 -0.290563150367013 -0.908390853676136 9.12249843262496e-11 247.693665356054 73.2798291866883 3.38010702406289 0.000776757668781158 -583.592485801657 139.973569497162 -4.1693048759001 3.55664361131147e-05 DDAH1 other 7.88275089563123e-07 0.413922183484428 1 3.38010702406289 -4.1693048759001 4.45181202410732e-27 95.1492540868809 47.3030164206289 2.01148386058074 0.0447706971115606 -1007.28195806832 104.35621367227 -9.65234289959666 1.92039210144321e-20 SREK1 other 5.91423227402658e-23 2.96124462042543e-16 1 2.01148386058074 -9.65234289959666 1.81970205627168e-10 105.108991954369 73.5434472740657 1.42920947889037 0.15351590302564 -952.713801948269 170.137540159709 -5.59966836862666 3.40614822268043e-08 CHD1 other 1.55202388379411e-06 0.000457581952234889 1 1.42920947889037 -5.59966836862666 0.23481745244123 -0.994568644661883 3.87697626867244 -0.256532043463461 0.797644308028491 -25.8559412571649 15.1862531556406 -1.70258858404196 0.0892592349559738 ANKFN1 other 1 1 1 -0.256532043463461 -1.70258858404196 1.19452023477847e-16 70.5032021102664 9.22762333390819 7.64045080288361 1.08584233919762e-13 -106.221928789848 35.3628001081991 -3.00377595848865 0.0027980428381595 DGKE other 1.29892130329811e-12 1 1.35089645419576e-09 7.64045080288361 -3.00377595848865 6.08369403548594e-20 328.471815668201 37.9271617139273 8.66059575313758 5.37468125075991e-17 -54.6417544605921 74.1704208791519 -0.736705465776196 0.46161964862574 HS2ST1 other 7.19640167457632e-16 1 7.12091518913181e-13 8.66059575313758 -0.736705465776196 6.85305226810217e-21 475.412738305528 79.3818008567409 5.98893868839658 3.99011240561827e-09 -1895.65343083978 284.704187668723 -6.65832647690287 7.17784128317631e-11 MSI2 other 8.26752225623845e-17 1.02822576381501e-06 4.33406009498256e-05 5.98893868839658 -6.65832647690287 0.407826672753509 10.8493999891082 30.7178074984257 0.353195780319418 0.724079505308878 -113.580353259197 97.201751945945 -1.1685010916507 0.243120297321089 CACNA2D1 other 1 1 1 0.353195780319418 -1.1685010916507 2.47876691679611e-76 67.7003353024184 3.56073478322762 19.0130238346625 3.8938621961136e-62 -33.6013165120136 11.2092301665128 -2.99764711874652 0.00284545754090733 ZUFSP other 3.84803776163429e-72 1 6.02263665872891e-58 19.0130238346625 -2.99764711874652 1.91637513905265e-15 43.6159338550012 5.92616054645609 7.35989744339344 7.53501992670571e-13 -64.4348385054376 23.0436320478102 -2.79621017953031 0.0053680441623663 GDPD1 other 2.00625313307422e-11 1 9.18217528268357e-09 7.35989744339344 -2.79621017953031 4.24580282428427e-45 278.148174284431 20.2884867071707 13.709656037881 6.52147213713419e-37 -113.869710854143 63.7029574630565 -1.78751058646186 0.0744167261370104 NUS1 essential 6.34195567863341e-41 1 9.787425383411e-33 13.709656037881 -1.78751058646186 0.0591686046446274 36.9323003883363 17.9523904625443 2.05723580184999 0.0401405601095135 97.594287897192 57.4075966506735 1.70002392699098 0.0896990759464981 SEMA3D other 1 1 1 2.05723580184999 1.70002392699098 2.52902878905405e-23 223.085066430574 33.7807051991324 6.60391975583458 9.58407501250399e-11 -338.926659630571 67.4028453371386 -5.02837317824362 6.73771654092487e-07 PPP2R5E other 3.18455305117686e-19 0.00862158208576747 1.10466048594121e-06 6.60391975583458 -5.02837317824362 1.34752041255274e-13 22.0390348747025 4.22023023809698 5.22223519365153 2.53880122676942e-07 -35.6776631742327 10.979619623338 -3.24944437040399 0.00122923678997588 SLC5A10 other 1.31922248388914e-09 1 0.00253448526468392 5.22223519365153 -3.24944437040399 0.00405349546820816 -172.522464383889 59.5158736359414 -2.89876387330225 0.00389952798627148 -312.087635172209 118.349556456242 -2.63699877310143 0.00860656163561672 AK5 other 1 1 1 -2.89876387330225 -2.63699877310143 1.56047746717205e-11 70.2081698321009 13.0899577315122 5.3635138685807 1.2210691693629e-07 -72.3029042009722 29.8200474347346 -2.42464081786648 0.0156568425957018 CABYR other 1.39959224030661e-07 1 0.00124036206223883 5.3635138685807 -2.42464081786648 2.96585599275037e-19 149.319939582311 38.3628959061678 3.89230103867898 0.000111936899836166 -580.762069265518 87.422954293393 -6.6431302163099 7.61856527346759e-11 IMPACT other 3.45403588915708e-15 1.09097854716056e-06 0.920233253553119 3.89230103867898 -6.6431302163099 0.0127029542663165 70.2357766206465 27.8353574005243 2.52325758243448 0.0119220156180382 -32.3274879646326 63.1576925522948 -0.511853531347197 0.608969162824882 ANKRD29 other 1 1 1 2.52325758243448 -0.511853531347197 1.36308839418005e-28 42.2788371320527 5.73697054411352 7.36954056273365 6.46019506234932e-13 -67.8690375251266 13.7584786220917 -4.93288824944284 1.08048280138606e-06 SDHAF4 other 1.84016933214307e-24 0.0136994414387739 7.88337603458488e-09 7.36954056273365 -4.93288824944284 0.0597728826721862 32.0192536979938 13.7049015860975 2.33633590849529 0.0198434230441693 13.8549015411786 30.8024462997299 0.449798740215648 0.653038433958422 CHST9 other 1 1 1 2.33633590849529 0.449798740215648 0.163766627813474 -359.690626961362 205.813331843901 -1.74765465258669 0.0810922273016595 -620.569274140686 381.871180418733 -1.62507490997413 0.104730066054662 THY1 other 1 1 1 -1.74765465258669 -1.62507490997413 0.298665322910178 15.9455380078263 12.4930104225039 1.27635673617172 0.202371078051693 1.67564686904383 27.1194616697181 0.0617876154567948 0.950754535491455 DNAAF1 other 1 1 1 1.27635673617172 0.0617876154567948 0.0117278920573732 30.5597676000275 15.6584012292124 1.95165311915849 0.0514912282296019 -19.212176511805 32.833590768151 -0.585137843968045 0.558697213673071 C16orf74 other 1 1 1 1.95165311915849 -0.585137843968045 6.37305618136728e-24 43.6490933268006 15.1339292411904 2.8841877499995 0.00407997256568716 -183.492280900778 27.2515836692251 -6.73327037165893 4.2317617113746e-11 TBCEL other 8.09951710089968e-20 6.08527334095668e-07 1 2.8841877499995 -6.73327037165893 0.000163105383760104 9.26215059927014 7.02146321403475 1.31911972147865 0.187687134562798 -34.3516654081718 14.9498739711587 -2.29778963183522 0.0219544698647166 JPH3 other 0.861848847788391 1 1 1.31911972147865 -2.29778963183522 0.0634530462473756 189.261915595769 81.3736445637815 2.32583801070165 0.0203945294514052 279.236117818606 410.298887861333 0.680567571786784 0.496435234482694 ANKH other 1 1 1 2.32583801070165 0.680567571786784 2.77720351646969e-19 162.701263524938 16.9735844215051 9.58555715072175 3.28332096000932e-20 181.467213354802 85.5835184536359 2.12035233691766 0.0344291282583235 OTULIN other 3.23710841879707e-15 1 4.52441628289285e-16 9.58555715072175 2.12035233691766 0.000427687752441561 79.3407313716048 20.3129801435271 3.90591290943035 0.000105660989191033 64.7411262689264 36.7078135857258 1.76368788943893 0.0783447942112123 UBASH3B other 1 1 0.870752211923301 3.90591290943035 1.76368788943893 0.103883708728563 -65.6200083510474 30.8831816309995 -2.12478134976807 0.0340575660593535 -61.3771522927422 55.6594866787829 -1.10272580570059 0.270636551160374 ROBO4 other 1 1 1 -2.12478134976807 -1.10272580570059 0.213923793935902 2.40295401525261 7.81291993306347 0.307561582076831 0.75853475995693 -17.196236279629 14.0768730693375 -1.22159489504002 0.222394875211165 ROBO3 other 1 1 1 0.307561582076831 -1.22159489504002 9.58758474323321e-33 58.3556167906447 17.8490095012621 3.26940364878614 0.00114549957601783 -266.295917228645 32.0976155028317 -8.29643925434746 8.4010076663861e-16 TBRG1 other 1.34532989117048e-28 1.26872017777763e-11 1 3.26940364878614 -8.29643925434746 0.000662092362624195 -0.122397948279556 5.14221541045555 -0.0238025711701394 0.981018947641638 -28.8724233033476 9.20536366702588 -3.13647829110437 0.0018037607748958 NRGN other 1 1 1 -0.0238025711701394 -3.13647829110437 4.56870653155393e-05 200.34660978577 70.1214812560114 2.85713601876592 0.00443930395250767 -1085.59202683436 353.223804547121 -3.07338297379541 0.00222313303656734 RETREG1 other 0.260142149906681 1 1 2.85713601876592 -3.07338297379541 4.02695601517161e-20 556.444406309615 61.3997506468135 9.06264928518066 2.2785140701056e-18 -573.43864699369 215.860004930403 -2.65653031546338 0.00812628656066999 TOMM70 other 4.77838600760263e-16 1 3.07599399464256e-14 9.06264928518066 -2.65653031546338 0.662278952744681 -44.8232156814661 71.530344942368 -0.626632175723187 0.531165184614481 -183.548609940382 250.412970978261 -0.732983635884887 0.463886467710069 ABI3BP other 1 1 1 -0.626632175723187 -0.732983635884887 0.00652703624188144 24.2698227987194 8.57872806997879 2.82907006735083 0.00484622815095852 140.761443379945 97.584182183998 1.44246168005523 0.1497662189208 ANGPT1 other 1 1 1 2.82907006735083 1.44246168005523 0.225907520727816 -147.225192320516 114.537267332086 -1.2853911722344 0.199205595262458 -370.902545943334 240.544129824638 -1.5419313961797 0.123674962227218 CYP4Z2P other 1 1 1 -1.2853911722344 -1.5419313961797 7.58243297604963e-09 80.459188174304 12.9217343634802 6.22665548687493 9.83078745234626e-10 57.7108017995249 55.2869435394056 1.04384142267499 0.29704377945518 PITPNC1 other 5.9120229914259e-05 1 1.0952480300659e-05 6.22665548687493 1.04384142267499 1.04105881812952e-27 185.689466156056 22.6709421494496 8.19063737766031 1.88918545366756e-15 -248.303476875339 47.1863836348907 -5.26218493022504 2.05666717656234e-07 CC2D1B other 1.39304080453911e-23 0.00268292233182557 2.43610464250431e-11 8.19063737766031 -5.26218493022504 0.986929081596021 -0.518408897691179 3.22350402541999 -0.160821545002922 0.872293768687172 -0.200193580245591 10.74081158193 -0.0186385897116369 0.985136264535831 CERS3 other 1 1 1 -0.160821545002922 -0.0186385897116369 0.000612981621795656 17.3164333071756 10.3128287504834 1.67911576213887 0.093730206917806 162.215101698293 43.2702378769634 3.748883982555 0.000197547830206381 PRKCA other 1 1 1 1.67911576213887 3.748883982555 4.66241020907966e-07 76.7822239910853 15.2940010186461 5.02041446822674 7.02555365486964e-07 167.351724451621 50.1108579910308 3.33962999559047 0.00089715414268064 LRRK1 other 0.00320121084955409 1 0.00682532537570585 5.02041446822674 3.33962999559047 0.340003007147247 5.29149866888667 4.01583362788706 1.31765883729372 0.188206019825193 -6.51034181701475 16.8745593460918 -0.385808108140172 0.699798729160822 CEP112 other 1 1 1 1.31765883729372 -0.385808108140172 0.0226832484647554 10.105208091264 5.84919385002153 1.72762407100369 0.0846231930388878 -15.9353111473412 11.330014628197 -1.40646871784993 0.160155962177444 GAL3ST2 other 1 1 1 1.72762407100369 -1.40646871784993 0.172134376193253 -13.9619253536805 10.5661085108547 -1.32138765557226 0.186951010417166 -60.8517883427322 39.3137455516451 -1.54785018544705 0.122264399327222 ABCA9 other 1 1 1 -1.32138765557226 -1.54785018544705 0.0753507787469295 -11.0886655802416 7.46614596075882 -1.48519271368686 0.138096415340078 -54.3252003290997 27.6586658203648 -1.96412945880783 0.0500452715352929 ABCA6 other 1 1 1 -1.48519271368686 -1.96412945880783 0.0422354450764461 -4.93048433770243 3.28833341972455 -1.49938698677199 0.134376635055556 -27.4554050512034 12.1653576031584 -2.25685145861025 0.024429244805824 ABCA10 other 1 1 1 -1.49938698677199 -2.25685145861025 7.99194800937898e-09 75.9546471812217 14.0310997028288 5.41330678206988 9.43417375548984e-08 -106.715903511093 51.8004798677295 -2.06013349265466 0.0398789894453659 ABCA5 other 6.21933394089872e-05 1 0.00096549334213683 5.41330678206988 -2.06013349265466 0.087604931550527 31.7328879355781 15.7266478537309 2.0177782468786 0.0441112123982841 4.91003251547348 37.2923903134038 0.131663121462844 0.895300069973283 ENPP3 other 1 1 1 2.0177782468786 0.131663121462844 0.0484707434268399 24.6657826816027 16.9882341011725 1.45193329304901 0.147096624119317 -31.2427276385652 32.2941539171023 -0.967442210090529 0.333752916335686 C4orf19 other 1 1 1 1.45193329304901 -0.967442210090529 0.00116726942920974 176.251436352838 87.9747207716071 2.00343274530427 0.045624525129842 674.568349847115 182.806961275821 3.69005832786269 0.000246680001204568 UCHL1 other 1 1 1 2.00343274530427 3.69005832786269 8.16827841672048e-06 412.408033033776 95.5101041212031 4.31795187355703 1.87588361978506e-05 -1079.28152082102 590.855112605549 -1.82664327987551 0.068308402944162 MIA3 other 0.0500225370239962 1 0.16520907039447 4.31795187355703 -1.82664327987551 0.000155039752727664 17.7331122698665 5.93664204323451 2.98706105921873 0.00294514464269946 -97.1819925235644 36.7018420779366 -2.64787779090755 0.008337531502286 DISP1 other 0.822485888220258 1 1 2.98706105921873 -2.64787779090755 0.0317098444033734 106.284441125951 49.0551440096395 2.16663192559512 0.0307053082897501 -292.211853613951 206.961242075917 -1.41191582869783 0.158558277877077 TNIK other 1 1 1 2.16663192559512 -1.41191582869783 1.01557536298767e-05 41.5724042778569 19.4933683137393 2.13264345128881 0.0334027256837951 -84.2416865267327 40.6023058436524 -2.07480055076485 0.0384763078762824 FAM167A other 0.0617368263160203 1 1 2.13264345128881 -2.07480055076485 5.37147235687916e-44 196.741536265671 18.7884477042379 10.4714098451728 1.74102607271236e-23 -95.5931482938412 39.1756434358993 -2.44011686624253 0.0150030628032781 NEIL2 other 7.99275086703619e-40 1 2.46860086849885e-19 10.4714098451728 -2.44011686624253 0.00381729777664929 -30.8504109758358 20.0241261773818 -1.54066203451528 0.123992514631507 -169.501606822817 51.1742783583862 -3.3122422486499 0.000988277864798456 PGM5 other 1 1 1 -1.54066203451528 -3.3122422486499 0.261211644683556 156.369829651339 100.4892858402 1.55608459492886 0.120311952455072 -243.380248846032 608.312966402884 -0.400090516375483 0.689258362209141 OBSCN other 1 1 1 1.55608459492886 -0.400090516375483 2.37326412320325e-32 153.374418051963 19.5434335116457 7.84787473299252 2.34715796888675e-14 -126.878542343852 40.9486818508249 -3.09847684001325 0.00204816812467645 LONRF1 other 3.31663661217654e-28 1 2.96352165151641e-10 7.84787473299252 -3.09847684001325 1.97166580922081e-12 1099.26739389141 146.636251385478 7.49655957176411 2.68941830780771e-13 -139.130228967385 948.874256934213 -0.146626624076526 0.883481258516708 ENAH other 1.84153586581224e-08 1 3.31659065718847e-09 7.49655957176411 -0.146626624076526 3.66994181091688e-09 86.3358259892151 13.7645423844886 6.27233536557725 7.28574929123641e-10 117.439065864276 82.2761810791792 1.42737623846757 0.154048403624374 CCSAP other 2.91576876877346e-05 1 8.15348203182267e-06 6.27233536557725 1.42737623846757 2.67797666673546e-10 53.4022811051453 61.8777350896659 0.863029020499231 0.388503933818979 -758.309459660706 130.572180350121 -5.80758824450469 1.08181520953423e-08 SH3RF1 other 2.2615512950581e-06 0.000147689412405614 1 0.863029020499231 -5.80758824450469 0.000507561209257021 209.804473195789 56.3728872146389 3.72172658811959 0.000218974438399164 305.3392740197 117.018571879646 2.60932319643879 0.00932798710957146 GBP5 other 1 1 1 3.72172658811959 2.60932319643879 1.19570827691914e-108 2471.62524353628 87.9159901661136 28.1134892397418 4.51883339484199e-108 566.672493591448 323.672077117762 1.75076113651062 0.0805507167787595 BUB3 essential 1.86960946179077e-104 1 7.06700354619338e-104 28.1134892397418 1.75076113651062 0.138029746660715 -17.8835539170761 39.2342660115267 -0.455814667510846 0.648705484389282 -160.498849629946 81.3375931262316 -1.97324316421388 0.0489745302991864 GPR26 other 1 1 1 -0.455814667510846 -1.97324316421388 0.000311404998969823 -0.0898058286109196 1.2265766740655 -0.073216644755894 0.941660683039803 -12.309444259161 3.15587989504069 -3.90047931751291 0.000108040542995641 CCDC173 other 1 1 1 -0.073216644755894 -3.90047931751291 0.705479013350394 -0.50013944432213 6.39426539257984 -0.0782168730285282 0.937684567975481 9.05638850525969 12.2470921906966 0.739472551054957 0.459942025428782 C10orf90 other 1 1 1 -0.0782168730285282 0.739472551054957 0.000154792047560406 -0.62921483471414 17.4923993549085 -0.0359707563238074 0.971318969704543 -129.017370291199 33.3071605085702 -3.87356257096733 0.000120416927561893 FAM69A other 0.821326604355516 1 1 -0.0359707563238074 -3.87356257096733 8.35922498123716e-12 681.922704569761 99.5857834654327 6.84759089942254 2.03854873202704e-11 -123.697295820335 241.757884338138 -0.511657752792558 0.609098564102472 ATP5G3 other 7.60856657792206e-08 1 2.39651788937099e-07 6.84759089942254 -0.511657752792558 7.14862898150298e-09 23.9664042345169 4.51245836443436 5.3111635164131 1.59248056635668e-07 1.71090111358596 10.1069179823019 0.169280201598737 0.865639406609211 SRSF12 other 5.58593868614643e-05 1 0.00160713138756716 5.3111635164131 0.169280201598737 0.163076097867566 146.172247308793 239.734540490149 0.609725436351128 0.542297352771697 959.654557916378 506.63864439542 1.89415980903223 0.0587320266786264 PDLIM3 other 1 1 1 0.609725436351128 1.89415980903223 0.851781841309594 -57.4091194078338 121.437686833136 -0.472745495282019 0.636583333025485 20.1188788172635 256.743898183716 0.0783616629629389 0.937569024652859 SORBS2 other 1 1 1 -0.472745495282019 0.0783616629629389 4.61931629366902e-66 279.729578226176 13.9004815783089 20.1237328829443 4.26750727446723e-67 26.1930366010372 139.790342736386 0.187373720446709 0.851440432809162 ELOC other 7.13407208394243e-62 1 6.6146362754242e-63 20.1237328829443 0.187373720446709 0.31106954896634 3.26203337760215 2.26977753151722 1.43715995612207 0.151270523527102 14.6826908263025 23.030980552078 0.637519136152356 0.52406573831082 LY96 other 1 1 1 1.43715995612207 0.637519136152356 5.76920133367148e-09 367.799123946851 61.3755949246975 5.99259566278922 4.02632564380892e-09 23.5323929101522 177.655973395955 0.132460465360789 0.894674914228445 CXADR other 4.53055380733221e-05 1 4.37218701661211e-05 5.99259566278922 0.132460465360789 8.39164560220502e-11 214.143023676097 30.8971085969541 6.93084348019569 1.33260386763571e-11 134.371915936999 88.4556984777615 1.51908716170254 0.129389472005624 BTG3 other 7.2654867623891e-07 1 1.57553755270571e-07 6.93084348019569 1.51908716170254 2.98119621796379e-11 149.580183195867 21.7046499703131 6.89161923368761 1.71422698919687e-11 31.4984858500248 62.1384997018343 0.506907730330911 0.612448998515271 C21orf91 other 2.64044549025053e-07 1 2.01987366137068e-07 6.89161923368761 0.506907730330911 3.78451911581564e-08 41.6792504822269 7.0475577956304 5.91399910307493 6.29252645864446e-09 51.4202948470658 20.0828569654209 2.56040736313575 0.0107554701762413 CHODL other 0.000282552197186796 1 6.79026530152323e-05 5.91399910307493 2.56040736313575 0.0383830370865687 -136.856835283792 57.1691851066117 -2.3938916573426 0.0170472677110935 -273.268003366651 166.42739676069 -1.64196525743649 0.101241426301461 NCAM2 other 1 1 1 -2.3938916573426 -1.64196525743649 9.7300933926718e-18 125.837734352129 13.7908106054421 9.12475255823405 1.45888350673903e-18 84.0311290409255 32.8893906334901 2.55496156731343 0.010895575284133 L3MBTL4 other 1.09103537212029e-13 1 1.9744529380206e-14 9.12475255823405 2.55496156731343 0.769390234923334 -10.0228332698793 14.1272971377253 -0.709465736592634 0.478340027432458 -0.442636380942001 59.283417757408 -0.00746644504797784 0.994045436366689 PDE1C other 1 1 1 -0.709465736592634 -0.00746644504797784 5.65206014250406e-19 97.7231829747928 15.7203913359411 6.21633271630911 1.03434393094389e-09 -333.391518279188 58.1745567647031 -5.73088196662412 1.68098888377564e-08 RABGEF1 other 6.52982508263494e-15 0.000228110191528354 1.15122479514055e-05 6.21633271630911 -5.73088196662412 4.732124655932e-16 87.6476537886839 11.7515828966534 7.45837003912417 4.07203022705202e-13 -56.1741471019336 32.8034791619825 -1.71244479357045 0.0874539068088597 MRPL39 essential 5.05059664527623e-12 1 4.99312346441119e-09 7.45837003912417 -1.71244479357045 0.00830251950430388 -54.9908183377418 23.9463707876264 -2.29641555396598 0.0220775786616998 -184.033919161948 66.8441249187552 -2.75318016932123 0.00612335802319027 JAM2 other 1 1 1 -2.29641555396598 -2.75318016932123 1.57854048040878e-15 265.73864494139 43.310434520678 6.13567256672331 1.76277292205187e-09 -426.368128252399 120.897154773938 -3.5267010960651 0.000460745038338073 ATP5J other 1.6569939422851e-11 1 1.94187065093234e-05 6.13567256672331 -3.5267010960651 1.31688912027936e-15 89.2730700508931 18.736104393931 4.76476156269766 2.50355746348359e-06 -268.182783847344 52.6308088502239 -5.09554745036383 4.99408800980033e-07 GABPA essential 1.38694762147823e-11 0.00642639245101107 0.0235209223694283 4.76476156269766 -5.09554745036383 0.662813385560227 -9.07755665774523 113.591051465251 -0.0799143642095979 0.936338741300002 -279.040831520476 318.206329712624 -0.876917916034169 0.38097080535847 ADAMTS1 other 1 1 1 -0.0799143642095979 -0.876917916034169 0.343472516735863 17.1204404326193 37.5494919147982 0.455943331309689 0.648636078374198 -120.250429091193 104.767526434595 -1.14778341327227 0.251627340967413 ADAMTS5 other 1 1 1 0.455943331309689 -1.14778341327227 2.3864712339657e-32 49.622235542055 5.13325556000202 9.6668157199708 1.71303629605314e-20 -78.9061907781547 13.0971272626147 -6.0246945147574 3.14062971691168e-09 TSEN2 essential 3.33485490234368e-28 4.34945809495098e-05 2.36655964299742e-16 9.6668157199708 -6.0246945147574 1.22747310518631e-09 167.94634068742 25.7500600565651 6.52217277623791 1.58813625326155e-10 195.820953736688 75.2591195534905 2.60195647914148 0.00952236639494167 SLFN13 other 9.99776844174253e-06 1 1.81762194185784e-06 6.52217277623791 2.60195647914148 1.48143294017732e-25 74.4429328883852 28.2582685729372 2.63437700353937 0.0086719826404564 -715.153427564089 71.2956080949283 -10.0308202240435 8.0188366375327e-22 XPC ts 1.92882568811087e-21 1.24131591149006e-17 1 2.63437700353937 -10.0308202240435 9.83922019475487e-53 105.265912311042 7.22503881580367 14.5695981702948 8.15789900146913e-41 -124.6200215922 20.9673045372261 -5.9435403998137 4.9965188457288e-09 CCDC174 essential 1.49565986180469e-48 6.88820088072172e-05 1.23486117185238e-36 14.5695981702948 -5.9435403998137 1.07417205783811e-15 408.994053589672 49.0875728656448 8.33192658983383 6.55709840409594e-16 -11.1663156594344 142.148961159205 -0.0785536212742929 0.937416670326308 FGD5 other 1.13454052748862e-11 1 8.51963795644186e-12 8.33192658983383 -0.0785536212742929 3.57289568982004e-33 83.347672498066 18.0599087005713 4.61506610470458 4.9226784599226e-06 -273.786855780154 31.7330139636758 -8.62782388378089 7.11890980526745e-17 FLCN other 5.02956526255967e-29 1.08228785769481e-12 0.0453181779020475 4.61506610470458 -8.62782388378089 6.77391085054235e-16 92.3154790270252 11.4665331525659 8.05086226139479 5.23923219900202e-15 -26.4152882028188 28.3790759079021 -0.930801562691601 0.352370617386852 DPH3 essential 7.20202201629663e-12 1 6.69731051998428e-11 8.05086226139479 -0.930801562691601 1.19508793794768e-18 48.8644353365899 5.51237858555099 8.86449190276463 1.10636995949605e-17 -11.5449575811924 13.6428516126898 -0.846227600280713 0.397799239762636 OXNAD1 other 1.36980979447564e-14 1 1.48065491679356e-13 8.86449190276463 -0.846227600280713 2.28846120815809e-21 114.814588494772 27.3078683915901 4.2044507776422 3.06236599335648e-05 -371.405535581204 56.7492928372577 -6.54467248862992 1.38566595123157e-10 CXXC1 essential 2.78368421360351e-17 1.97526681348061e-06 0.265660249923675 4.2044507776422 -6.54467248862992 5.56862282442494e-15 137.102553848243 16.4362559827458 8.34147107420135 6.10457307366607e-16 135.943291056232 34.0827433142068 3.98862526419833 7.55828675334764e-05 SKA1 essential 5.74347758111188e-11 0.85967953532576 7.93899728230272e-12 8.34147107420135 3.98862526419833 1.66642809681139e-25 259.92739019447 44.6924793754946 5.81590893650423 1.03335161008463e-08 -596.830837382229 98.7112158654081 -6.0462312428205 2.76872937933772e-09 PPP4R1 other 2.16852288238066e-21 3.84050452207935e-05 0.000110537621730753 5.81590893650423 -6.0462312428205 0.330490155019831 82.3347210914264 66.092188737269 1.2457557037296 0.213399369596897 -27.3722016401353 145.312639254412 -0.188367658729344 0.850659878063912 APCDD1 other 1 1 1 1.2457557037296 -0.188367658729344 0.000714971654809688 -9.17463093154696 99.9689661291177 -0.0917747905854824 0.926911262349402 -805.629301452267 230.073087233692 -3.50162338037375 0.000500999018830345 PIEZO2 other 1 1 1 -0.0917747905854824 -3.50162338037375 0.000133788958414435 2.01683304471833 3.94683947573722 0.510999511664104 0.609565806512724 -30.6678465926453 8.69459939865195 -3.52722939683686 0.000456654861247366 CCDC144B other 0.715904716475643 1 1 0.510999511664104 -3.52722939683686 1.97735523208212e-21 16.4704137643182 15.0963308809098 1.09102098345937 0.275756601423348 -307.782365373175 35.0607104681859 -8.77855472017479 2.2523493212842e-17 MPPE1 other 2.40841867267602e-17 3.43438224509414e-13 1 1.09102098345937 -8.77855472017479 1.83103327985103e-13 73.3877451108512 11.925825072979 6.15368284053819 1.46939947773311e-09 -35.4366049987452 21.0799272041536 -1.68105917328608 0.0933254164902246 USP43 other 1.78306020791893e-09 1 1.62383336284286e-05 6.15368284053819 -1.68105917328608 7.45065640153823e-09 99.9243457404807 16.2556560454382 6.1470509379117 1.5262117958732e-09 113.888345500533 56.9208191752128 2.00082056356152 0.0459072061935237 RAB6B other 5.81300212448013e-05 1 1.68447995910525e-05 6.1470509379117 2.00082056356152 1.37062119113313e-72 201.623622152019 9.42836913502074 21.384782380137 1.77144022013491e-73 112.511740966398 41.5249401360307 2.70949796911982 0.00695830570248673 EME1 other 2.12418872201813e-68 1 2.75405811024374e-69 21.384782380137 2.70949796911982 0.064864072040599 44.5174384640433 19.340833934546 2.3017331421541 0.0217271484808499 -4.1220502463295 69.9217866448295 -0.0589523014803328 0.953011748691717 EPHB1 other 1 1 1 2.3017331421541 -0.0589523014803328 9.58005338221698e-09 235.185121092222 57.3856706179436 4.09832487029756 4.80611944424768e-05 -827.711938200215 244.862226165982 -3.38031696909895 0.000776773305926377 ACSS1 other 7.41591932317416e-05 1 0.408616275149938 4.09832487029756 -3.38031696909895 4.39127636068166e-75 413.039565790998 20.580738190927 20.069229876948 1.04427228262147e-66 -477.125605959607 99.5672540625617 -4.79199321555872 2.1600304424495e-06 ANKRD40 other 6.81262614596152e-71 0.0270111806828309 1.61820432915023e-62 20.069229876948 -4.79199321555872 3.87182044593142e-62 33.6223510290574 7.0574414455117 4.76409918362696 2.44689395821279e-06 -178.317124935352 12.4113803315713 -14.3672275098814 8.05413511621046e-40 ZNF18 other 5.96221630468979e-58 1.26256622081715e-35 0.0230154845709495 4.76409918362696 -14.3672275098814 0.189319388645957 1.28997851652541 1.79069685238721 0.720377943818753 0.471624969012902 11.4337060882748 6.39917572282699 1.78674669731115 0.0745769709609269 CA10 other 1 1 1 0.720377943818753 1.78674669731115 8.05748993436602e-09 245.997332764036 43.5651747190691 5.64665089375527 2.67283368414605e-08 -283.449887950227 188.501710442737 -1.50369928890557 0.133255565840959 VOPP1 other 6.26792141994332e-05 1 0.000281235560245847 5.64665089375527 -1.50369928890557 0.000257131210795478 -23.3542897131377 8.90027149098744 -2.62399745185152 0.0089367747861909 -76.0704929747376 19.3285834228945 -3.93564760077726 9.38377736712458e-05 DKK2 other 1 1 1 -2.62399745185152 -3.93564760077726 0.0664226188468794 -1.647318283289 10.758955487047 -0.153111357814636 0.878367655080114 -51.3046373293672 23.3763693414102 -2.19472222482742 0.0286085686775392 CYP2U1 other 1 1 1 -0.153111357814636 -2.19472222482742 1.656853857988e-16 62.5834512759552 7.29524460164511 8.5786638684935 1.0044909885475e-16 7.3238769316371 25.5761505067367 0.286355717593545 0.774714706285891 RSPH10B other 1.79255018895722e-12 1 1.32412002110332e-12 8.5786638684935 0.286355717593545 6.04933251694155e-09 32.8424243155297 5.59661691488637 5.86826377702797 7.70395395447943e-09 -12.1372439228271 19.8335336970231 -0.611955696258445 0.5408255938672 FBXL18 other 4.74328162653387e-05 1 8.28406168725173e-05 5.86826377702797 -0.611955696258445 6.89479229063953e-05 465.836861925842 157.771927577466 2.95259663159732 0.003303336172121 -1584.40124606954 594.883842305113 -2.66337919001152 0.00799227353078579 PROM2 other 0.38293676382212 1 1 2.95259663159732 -2.66337919001152 2.27440211584632e-50 88.0416841140551 5.88173955733323 14.9686471588642 1.41045111756382e-42 -13.8172698434797 17.6205571038573 -0.784156242168695 0.433294832604653 AK9 other 3.442535042545e-46 1 2.14106479646188e-38 14.9686471588642 -0.784156242168695 1.47556695824016e-06 138.552610775444 26.7293749486931 5.18353351103028 3.09742677298547e-07 -235.4367594685 327.895492468103 -0.718023775491218 0.473057815443274 KLF10 other 0.00969742604955431 1 0.00307791298431567 5.18353351103028 -0.718023775491218 0.0368057255270728 150.827442612686 95.5583187253199 1.57838108313977 0.115068038299118 -395.210466824599 282.970913743882 -1.39664696132799 0.16309778669102 PTPRN2 other 1 1 1 1.57838108313977 -1.39664696132799 1.35841011874103e-61 1357.20185675944 70.94504531968 19.1303261650459 1.80901468265865e-62 -1316.21382797477 890.83782373521 -1.47750105900981 0.140133110303863 AZIN1 other 2.09072901375432e-57 1 2.79854571407293e-58 19.1303261650459 -1.47750105900981 5.52071512844923e-64 572.772135121524 29.2712509409438 19.5677368308283 1.24272795109731e-64 -713.901741492817 363.734743918698 -1.96269878923744 0.050201878894874 ATP6V1C1 essential 8.51625515714578e-60 1 1.92411568668396e-60 19.5677368308283 -1.96269878923744 9.03026748992274e-41 94.1738483067898 6.3373052180102 14.8602355523534 6.34738391945431e-42 39.3278410827605 64.0899395103005 0.613635172435133 0.539723225951587 OTUD6B other 1.32663659694455e-36 1 9.62644245224441e-38 14.8602355523534 0.613635172435133 3.16143119500458e-23 266.441805722417 33.7782983018948 7.88795821924134 1.71983923499577e-14 -291.604899036799 96.0442510838003 -3.03615152126459 0.00251202601715824 CDK19 other 3.97518358459876e-19 1 2.17817639112214e-10 7.88795821924134 -3.03615152126459 6.92235949768779e-36 199.430785387368 19.3847989806025 10.2879986316562 8.63635215497952e-23 -205.547228837113 55.0382847125755 -3.73462272508192 0.000207976357239563 GTF3C6 essential 9.93773929488059e-32 1 1.21763929033056e-18 10.2879986316562 -3.73462272508192 9.21106027438214e-11 143.635986244782 25.1805676538801 5.70423940473194 1.92543323248145e-08 -87.0716848545937 58.3915130144578 -1.49117021223675 0.136499639407361 TTC39B other 7.9565138650113e-07 1 0.000203768598993512 5.70423940473194 -1.49117021223675 3.31131165663597e-20 210.337014424984 31.4355802870006 6.69104920299383 5.60954698313166e-11 -125.088960656674 68.3245785867458 -1.83080471543428 0.0676867822867846 AGPAT5 other 3.93615616624318e-16 1 6.50370877224284e-07 6.69104920299383 -1.83080471543428 4.87063640258037e-23 136.266240029412 30.829110160592 4.42005102708407 1.19042815260103e-05 -421.932505819627 59.8829731959773 -7.04595118279749 5.56505181235248e-12 MMS19 essential 6.10582979427475e-19 8.1088369957788e-08 0.106590936783896 4.42005102708407 -7.04595118279749 3.61206064050814e-13 47.2068153581717 22.141875363816 2.13201522375636 0.0334504750405289 -251.823826907183 42.4958588026664 -5.92584392932382 5.50111204987634e-09 PI4K2A other 3.47444113010478e-09 7.57448118147474e-05 1 2.13201522375636 -5.92584392932382 0.367870958677426 -19.2592019648365 63.429533639484 -0.303631460926396 0.761524135057669 -168.548307098357 121.73731724041 -1.38452457240785 0.166762397106138 MARVELD1 other 1 1 1 -0.303631460926396 -1.38452457240785 5.49971865176216e-22 68.8121875697013 21.7032798643816 3.17058933026213 0.00160649167128445 -319.358471535224 41.6540831125229 -7.66691876694346 8.09634828394335e-14 ZFYVE27 other 6.77565337897098e-18 1.20368409937386e-09 1 3.17058933026213 -7.66691876694346 0.47960474296279 -12.5779582518595 11.5723594080447 -1.08689661359081 0.277561211693858 0.951011212637914 22.1939697502191 0.042849982375439 0.965836756958026 GOLGA7B other 1 1 1 -1.08689661359081 0.042849982375439 0.0345114575118568 -39.7128009865928 20.7781597924707 -1.91127613721516 0.056496243837801 -111.019993910582 45.8272801730437 -2.42257435945075 0.0157377423762223 GPR78 other 1 1 1 -1.91127613721516 -2.42257435945075 1.06990660573817e-22 19.2410146113466 7.85245249439093 2.45031913597575 0.0145868753975215 -141.138111930919 17.2646467239921 -8.17497827712769 2.0925477765193e-15 TRMT44 other 1.33460149999779e-18 3.15284173488162e-11 1 2.45031913597575 -8.17497827712769 5.83960526628836e-11 61.339262512209 20.173612490862 3.04056908696912 0.00247480576921272 -181.77282514963 39.6711052240494 -4.58199548822843 5.71437972678348e-06 SLC25A28 other 5.09622351588986e-07 0.0699848646518278 1 3.04056908696912 -4.58199548822843 4.43771557907017e-06 186.561376871852 44.3805094231942 4.20367813025487 3.11663541692533e-05 -179.165948425455 131.626158882349 -1.36117280901282 0.174078395983222 HSPA13 other 0.0278555406898235 1 0.270087625230749 4.20367813025487 -1.36117280901282 0.498938102831292 -8.51343926989013 8.55374428745285 -0.995288026365034 0.320082475570488 -22.9498380337337 25.3691658624999 -0.904635105392156 0.366098798915621 SAMSN1 other 1 1 1 -0.995288026365034 -0.904635105392156 1.21498166578177e-07 147.515360803043 31.7922173392375 4.63998340313878 4.47587643652404e-06 -168.170629809804 94.2469319579366 -1.78436184941129 0.0749822512942389 USP25 other 0.000873936312196829 1 0.0413191960914077 4.63998340313878 -1.78436184941129 4.010888057487e-31 42.7289038322391 9.46078988790383 4.51642033471967 7.72043719516076e-06 -200.650664424654 22.0304576075044 -9.10787546947301 1.60371141949151e-18 ZCCHC10 other 5.54705818350452e-27 2.45768775037075e-14 0.0701401719180355 4.51642033471967 -9.10787546947301 6.17612645631588e-39 32.943513286961 5.49471683805811 5.99548880458845 3.98116592441058e-09 -112.654034247073 14.5614831884794 -7.73643953633799 6.03445532805229e-14 C16orf87 other 9.00417476066292e-35 8.98047641920742e-10 4.32474054368722e-05 5.99548880458845 -7.73643953633799 1.62181169206384e-19 359.019108754601 48.2411134686755 7.44218122137093 3.89312941906221e-13 -264.98743087618 105.670747879266 -2.50767062970863 0.0124431541682252 MOV10 other 1.90141202777564e-15 1 4.77764842307314e-09 7.44218122137093 -2.50767062970863 4.83859246848833e-09 476.344485718154 260.999801642682 1.825076044963 0.0685377645513493 -2691.92939805298 571.712430597832 -4.70853746391007 3.17039401527935e-06 RHOC other 3.81716559839044e-05 0.0393255673655251 1 1.825076044963 -4.70853746391007 0.000194891746733881 49.8723571125579 27.2882635138495 1.82761197271663 0.0681554154469182 -157.4022474919 59.7741429767652 -2.63328321667588 0.00869689967112643 PPM1J other 1 1 1 1.82761197271663 -2.63328321667588 0.188159812871769 614.86995507887 336.17231870893 1.82903207926303 0.0679430793270671 448.824616081065 811.11780932519 0.553340847557601 0.580257786453195 DBI other 1 1 1 1.82903207926303 0.553340847557601 0.00395055949008893 286.517729496217 100.509479676338 2.85065379324283 0.0045291100790836 -86.2782728686461 220.070522949838 -0.39204829302974 0.695176639188218 SLC16A1 other 1 1 1 2.85065379324283 -0.39204829302974 1.01083733847901e-41 72.1607299754662 13.6680601823226 5.27951508940487 1.92167637675679e-07 -311.88295396161 35.3027203548741 -8.8345303372223 1.63384781675678e-17 HEATR3 other 1.49128832545809e-37 2.49276161402582e-13 0.0019318612615536 5.27951508940487 -8.8345303372223 1.02308979078926e-08 114.829807093198 23.3894634151537 4.90946735523661 1.21222147344316e-06 -132.41695316598 57.645275590382 -2.29709983706061 0.0219954921486342 NIFK other 7.90336863384704e-05 1 0.011611869494112 4.90946735523661 -2.29709983706061 1.21029129479188e-61 535.855746832174 34.2906492453575 15.6268766741044 9.95216983422143e-46 -627.772911881396 107.403184860924 -5.84501207011967 8.74432815423242e-09 OXA1L other 1.86300139007314e-57 0.000119779807056676 1.51760637802043e-41 15.6268766741044 -5.84501207011967 0.0575594460585611 9.26680462434807 13.2510824666354 0.699324349363968 0.484649353354057 103.649393476342 43.2622300372277 2.39584028347938 0.016920431529264 SLC7A7 other 1 1 1 0.699324349363968 2.39584028347938 7.22132176705663e-12 790.398818090629 129.962761078241 6.08173304054988 2.24650422354061e-09 -547.403226093633 303.323915117555 -1.80468205377569 0.0716793675212058 LARP1 other 6.59523316985282e-08 1 2.46374118195699e-05 6.08173304054988 -1.80468205377569 1.26037579198617e-21 204.057466231781 43.2867533763158 4.71408572636057 3.09255296113091e-06 -706.032224963577 101.013313953076 -6.98949670428148 8.15213626313165e-12 CNOT8 other 1.54068336812389e-17 1.18499452720882e-07 0.0288627967862348 4.71408572636057 -6.98949670428148 0.182903831789513 33.0072330629689 37.8958794991613 0.870997942235368 0.38413877303403 -108.364052167926 87.6457472553784 -1.23638688198048 0.216847352280782 GRIA1 other 1 1 1 0.870997942235368 -1.23638688198048 2.16142417479838e-05 -2.33637418551836 1.74088754849445 -1.34205922004491 0.180134595500303 -26.3880929495737 5.64360011880554 -4.67575526154725 3.69525617880708e-06 LRGUK other 0.127178198445136 0.0456585853453403 1 -1.34205922004491 -4.67575526154725 4.06224358039932e-17 13.9335356980415 5.28586474863144 2.635999285008 0.00863207760557588 -79.884467157417 11.8952290017479 -6.7156729093386 4.78576862039721e-11 SETD9 other 4.47984222046437e-13 6.87762808437283e-07 1 2.635999285008 -6.7156729093386 2.18054540146865e-18 49.1080040154834 23.4562656948964 2.09359855717222 0.0367650409498221 -401.549929769404 53.9733435220546 -7.43978237341036 4.03424492797863e-13 MIER3 other 2.48625786675456e-14 5.95172154224687e-09 1 2.09359855717222 -7.43978237341036 1.34968236129145e-10 368.057457963008 64.6043150987159 5.69710331888224 1.99596743709314e-08 -375.028073602174 208.797182310721 -1.79613570188929 0.0730266584697189 NUP205 essential 1.15667778362677e-06 1 0.000211088194505265 5.69710331888224 -1.79613570188929 2.51895654408106e-20 55.97376934944 6.79131353986776 8.24196512513395 1.27828992831782e-15 -128.587719633035 38.4251559996595 -3.3464462612507 0.000875182233958202 ZKSCAN2 other 3.0020924092358e-16 1 1.65155058738662e-11 8.24196512513395 -3.3464462612507 1.61070424078285e-12 17.2734308989902 4.90903667997972 3.51870071972279 0.000469824652406246 -57.5701362285923 11.0088218906485 -5.22945477730867 2.42585442947765e-07 C9orf85 other 1.51003522573392e-08 0.00315652178363632 1 3.51870071972279 -5.22945477730867 0.00196687775126431 15.7985056344303 30.5238142832547 0.517579667069894 0.604961583759131 202.134636161416 58.9836560515968 3.4269601054332 0.000656449504788795 PIK3AP1 other 1 1 1 0.517579667069894 3.4269601054332 3.96494996899869e-08 8.13584574904067 4.53628786104287 1.79350296944565 0.0734540310183733 -55.153192592657 11.2456394932868 -4.90440695930022 1.24315053161582e-06 RBM45 other 0.000295507721189472 0.0157183953217504 1 1.79350296944565 -4.90440695930022 0.745595025220081 1238.67187785173 1922.33687482183 0.644357341356488 0.519639819754322 -1045.51061553977 4843.0943947151 -0.215876571945543 0.829172172775299 TTN other 1 1 1 0.644357341356488 -0.215876571945543 4.58783314765206e-09 995.737559241708 188.223634037215 5.29018347953495 1.77869993763702e-07 -912.825945031799 586.355182683651 -1.5567798699313 0.120108611513569 PDIA4 other 3.62438818664513e-05 1 0.0017900836172379 5.29018347953495 -1.5567798699313 2.10217517259335e-24 20.5321777497636 2.36716014742128 8.67375947171585 4.87601123040464e-17 -62.0980401040025 13.5420408398323 -4.58557471790725 5.62750105562186e-06 KDM8 other 2.69246596105756e-20 0.0689537704345347 6.46510329039352e-13 8.67375947171585 -4.58557471790725 0.29766626734223 -0.184506589503859 0.865053083741118 -0.213289326368179 0.83118120615481 -7.23825320413111 4.67928574434239 -1.54687138157414 0.122475784561429 OTOA other 1 1 1 -0.213289326368179 -1.54687138157414 5.1683781683166e-14 30.1093067270317 10.4028956362362 2.89431979132354 0.00395369935544418 -168.821523886605 25.7835616867665 -6.54764170821492 1.36444715780087e-10 KCTD18 other 5.13788473712353e-10 1.94515586816092e-06 1 2.89431979132354 -6.54764170821492 2.45730400058491e-06 75.6297883996598 18.3946342420672 4.11151357533928 4.54392620904233e-05 -92.4416285229942 45.8483245139434 -2.01624878341805 0.0442695192022879 FAM126B other 0.0158397815877703 1 0.38746058784504 4.11151357533928 -2.01624878341805 5.12887531269572e-05 114.918429726616 28.1604456446389 4.0808455653291 5.16116262569903e-05 -48.0027495400616 69.2266050482893 -0.693414757325988 0.488345798146548 TMEM237 other 0.289371145142293 1 0.437718202285535 4.0808455653291 -0.693414757325988 0.00453629286369719 336.760990135756 102.122063302958 3.29763206151361 0.00103884047211532 264.786412784369 250.258797114766 1.05805036960575 0.290502933132968 FZD7 other 1 1 1 3.29763206151361 1.05805036960575 0.0454654760886684 44.1825703240403 20.6309893601601 2.14156333236059 0.0326900048532681 -41.9335553113386 70.4917989368164 -0.594871402685079 0.552186708129181 SPAG17 other 1 1 1 2.14156333236059 -0.594871402685079 0.00483690256340512 59.2836613932843 25.7560212155924 2.30173988820116 0.0217352898838909 -662.76298145508 286.555780966129 -2.31285852695262 0.0211110245761526 DEPTOR other 1 1 1 2.30173988820116 -2.31285852695262 0.297513190106061 1.27046714673088 1.3232257845854 0.960128771318461 0.337419313095275 -9.38077323439776 8.14097610950655 -1.15229096710448 0.249710446119115 FMN2 other 1 1 1 0.960128771318461 -1.15229096710448 2.11033002192262e-21 197.484633676148 39.9771844907916 4.9399335193712 1.04163968194128e-06 -567.039446807215 83.5570881688126 -6.7862518816071 3.01522510905529e-11 RNF20 essential 2.56911576868859e-17 4.34765308474682e-07 0.0100091157037738 4.9399335193712 -6.7862518816071 4.85950031602431e-09 10.3605362053857 8.14303572049409 1.27231864884378 0.203799521844621 120.122120125977 19.2862007822326 6.22839726093902 9.39112276644963e-10 PPARGC1B other 3.83268789924837e-05 1.31644758940091e-05 1 1.27231864884378 6.22839726093902 0.175296295136596 35.168209505335 20.3810336193297 1.72553611176917 0.0849998254638369 87.9660667313289 76.9830623222345 1.1426678035114 0.253680112981145 ELMO1 other 1 1 1 1.72553611176917 1.1426678035114 0.00015740332806148 222.41411182983 116.906596097926 1.90249412140549 0.0576324255569803 1161.74928309175 277.369747284743 4.18844987409213 3.27454164145252e-05 SLC26A2 other 0.834395042053904 0.382040773308265 1 1.90249412140549 4.18844987409213 0.00126806073828764 8.27950964139343 6.27605872801092 1.31922118644952 0.187648135635367 -40.1724522236511 14.489223077047 -2.7725746239141 0.00575142775103839 LSM11 essential 1 1 1 1.31922118644952 -2.7725746239141 2.50002881495719e-51 38.7547863562999 5.37892572243721 7.20493056720256 1.93942591698542e-12 -147.842313375936 12.2829497915903 -12.0363850609532 9.26872050567671e-30 MED7 essential 3.79104369500108e-47 1.44999863590806e-25 2.34379622067687e-08 7.20493056720256 -12.0363850609532 2.0729556323732e-53 306.556774814317 31.4125999056357 9.75903859391524 8.19046950365337e-21 -698.001001665092 71.9763559064018 -9.69764296726516 1.36749233280946e-20 RRAGA other 3.15420929021906e-49 2.11017741875827e-16 1.13511716851132e-16 9.75903859391524 -9.69764296726516 0.00456568212162717 -34.4634312672134 10.4627851180139 -3.2939060564168 0.00105341382787174 -34.9565454923838 24.1146631442432 -1.44959708884546 0.147756833772671 SLC24A2 other 1 1 1 -3.2939060564168 -1.44959708884546 0.000555395958222379 48.8440788864945 18.7196829677173 2.60923643689521 0.009323252935465 -184.460297013998 69.9517093835563 -2.63696625342739 0.00860335875271652 PXYLP1 other 1 1 1 2.60923643689521 -2.63696625342739 7.59533438827823e-07 74.6878023401054 15.0895806568817 4.94962743090169 9.92692712193232e-07 -99.805700490072 57.2300734455764 -1.74393801162921 0.0817337117419642 RASA2 other 0.00513064837928195 1 0.00955069658401109 4.94962743090169 -1.74393801162921 0.00285814187348023 369.51476745348 114.20015446882 3.23567659931991 0.00128718291231928 101.919817785887 249.315440918823 0.408798658479688 0.68284800905772 RMND1 other 1 1 1 3.23567659931991 0.408798658479688 5.51774459236747e-06 13.2276922908196 2.67669822093884 4.9417944045183 1.03111187227137e-06 10.2814623960861 6.65651178474342 1.54457210150983 0.123029171209489 RAET1L other 0.0343148536199333 1 0.00991517176376145 4.9417944045183 1.54457210150983 0.210743700453189 16.496914549092 9.7386622537836 1.69396105124015 0.0908471955880104 -31.8925774738288 90.7219142065764 -0.351542157732788 0.725318271560265 SLA other 1 1 1 1.69396105124015 -0.351542157732788 1.74171183698895e-23 296.377476891314 45.7292685890706 6.48113311311848 2.09714659901301e-10 -1537.94203815919 206.859269183542 -7.43472624760463 4.28066050234916e-13 TMBIM4 other 2.19891119419855e-19 6.31397424096502e-09 2.39053740821493e-06 6.48113311311848 -7.43472624760463 0.000519474553243035 0.439569333665256 3.09782575791211 0.141896080676119 0.887215507078652 -18.4640148377185 6.30126588361489 -2.93020722800005 0.00353200466161489 MICU3 other 1 1 1 0.141896080676119 -2.93020722800005 0.000528150714253954 52.0131851977995 13.5614994688687 3.83535650443368 0.000140646426349809 71.2328044371542 48.8447689432201 1.45835072983883 0.14534299669971 GRIP1 other 1 1 1 3.83535650443368 1.45835072983883 3.79647492117955e-49 272.644598031819 28.1390419999209 9.68919261830539 1.43962883690463e-20 -252.41448764528 57.5843980790024 -4.38338327855719 1.40614624758511e-05 VPS37A essential 5.72698241859934e-45 0.168217275598607 1.99028686702065e-16 9.68919261830539 -4.38338327855719 0.126833584017836 13.7614411046234 8.03308732023412 1.71309492303917 0.0872969226778588 -14.5127849428228 22.8446282288174 -0.635282167757742 0.525526558940592 KIF5A other 1 1 1 1.71309492303917 -0.635282167757742 0.0205271402792824 -12.1441661863143 14.4827848470918 -0.838524242024684 0.402105303982128 -77.6670197197451 29.8756879443809 -2.59967301386788 0.00958515556373476 NAT2 other 1 1 1 -0.838524242024684 -2.59967301386788 4.48097466209008e-19 144.580490019512 156.447835097301 0.924145034858375 0.355822051435788 -2220.29487901148 323.904564739418 -6.85478107046039 1.9497904019364e-11 PSD3 other 5.19300153589619e-15 2.81920194215984e-07 1 0.924145034858375 -6.85478107046039 8.96102150658876e-15 99.0043701902795 18.8821061929441 5.24329061486138 2.26171891488095e-07 -180.287419544964 41.1321433923575 -4.38312727409343 1.40446898231026e-05 CARNMT1 other 9.17250161414426e-11 0.168044713733423 0.00226443297757881 5.24329061486138 -4.38312727409343 2.48164559347682e-15 148.860228003926 18.0131817163589 8.26396082313082 1.11641701441426e-15 43.0069581674555 45.5788639471282 0.94357240271157 0.34581410420234 MCU other 2.58934901223372e-11 1 1.44386212474196e-11 8.26396082313082 0.94357240271157 9.4656274908326e-18 11.5365935008802 51.6385705052447 0.223410396298799 0.823299827722189 -831.818682228105 102.055761439848 -8.15062932746213 2.49611522017345e-15 ELMSAN1 other 1.06175943564669e-13 3.75939913310323e-11 1 0.223410396298799 -8.15062932746213 3.60438187405249e-10 25.6500353569897 8.00740330212259 3.2032900541166 0.00143909310092947 -97.7897837471985 21.253629589707 -4.60108629137668 5.24719916948156e-06 CFAP70 other 3.02371595414263e-06 0.0644198642037251 1 3.2032900541166 -4.60108629137668 3.66600257515113e-06 28.9660885919722 15.3325138803954 1.88919369764987 0.0594004024147011 -129.507192985478 33.6508172927626 -3.84856010654254 0.000132997756325463 GNA14 other 0.0232204603110073 1 1 1.88919369764987 -3.84856010654254 8.94927184453061e-36 61.3280586269579 25.7316345521559 2.38337205134213 0.017496378222332 -563.747154938003 50.7704756217461 -11.1038383634235 5.77139924351199e-26 FAM161B other 1.28386253881636e-31 8.99818856055954e-22 1 2.38337205134213 -11.1038383634235 5.23700648621618e-13 101.704305937717 82.2026423779052 1.23723888911207 0.216537147841554 -1228.21155600033 179.821023066939 -6.83018890145637 2.29561911135858e-11 GNAQ other 4.9976752897961e-09 3.31625136826861e-07 1 1.23723888911207 -6.83018890145637 0.905874553332927 25.9449344495891 71.8809605011713 0.360943068494004 0.718287198034451 98.8916158604595 317.338592961163 0.311628078191429 0.755446903999889 WIF1 other 1 1 1 0.360943068494004 0.311628078191429 0.501368588126205 -134.636028005234 178.347478301113 -0.754908503824885 0.450656488926095 -597.918338629427 537.069311516957 -1.11329827604672 0.266111024874792 UGT2B4 other 1 1 1 -0.754908503824885 -1.11329827604672 0.241371791955468 -5.28718502910866 15.1162891783912 -0.349767391104606 0.72665570637805 -254.285708724638 152.552717352756 -1.66687105373967 0.0961456811577703 MMP16 other 1 1 1 -0.349767391104606 -1.66687105373967 3.11537150630134e-20 158.275069077741 20.0634427676284 7.88872931285312 1.76289533533712e-14 -164.548788335568 51.4719266905326 -3.19686475551796 0.00147232832371494 ADK other 3.70542286959481e-16 1 2.23217807360386e-10 7.88872931285312 -3.19686475551796 0.00148743076030365 -18.5165221037172 61.6357001838403 -0.300418784056774 0.763974003519578 -727.057322047815 203.426862397312 -3.5740477608498 0.00038316935349867 KCNMA1 other 1 1 1 -0.300418784056774 -3.5740477608498 2.2118858196032e-10 13.2314397987542 22.5390611393215 0.58704485146769 0.557416240407737 -264.775798929097 44.7955437572144 -5.91076202499394 6.00204256529195e-09 BATF other 1.87943938091684e-06 8.25580954855908e-05 1 0.58704485146769 -5.91076202499394 3.28210081622687e-15 192.126021797865 25.3735990934118 7.5718868691257 1.6113480407752e-13 -42.2211249366751 65.8901653851136 -0.640780375795111 0.521938223579393 DCK other 3.4127284287127e-11 1 1.99726589654086e-09 7.5718868691257 -0.640780375795111 8.61693897491528e-05 3.01884425622331 7.99908545107866 0.377398675721889 0.706025081258794 102.392530114999 24.2456934681653 4.2231223557058 2.82590262210404e-05 ADAMTS3 other 0.472035917045859 0.331280564389257 1 0.377398675721889 4.2231223557058 0.0241729731757342 7.65599083726592 6.2286010696396 1.22916699137852 0.219541579975861 -22.8976743726312 13.4456046237098 -1.70298584656087 0.0891429644085738 ALX3 other 1 1 1 1.22916699137852 -1.70298584656087 8.49881078075734e-36 183.431710055193 13.5714092896299 13.5160399440135 5.71651526082543e-36 -271.43875745224 157.065545483987 -1.72818778692564 0.0845381120525317 DPY19L4 other 1.21957934703868e-31 1 8.56162490613825e-32 13.5160399440135 -1.72818778692564 9.67651329873789e-48 178.572339085814 10.988162316413 16.2513379347411 1.74717104902148e-48 -123.661784717778 123.478305828843 -1.00148592003837 0.317048954300505 NDUFAF6 other 1.4551540698642e-43 1 2.67387057342247e-44 16.2513379347411 -1.00148592003837 8.50943205549286e-12 203.951753296584 44.4743847857895 4.58582517282513 5.61881446122285e-06 -325.907498781787 98.2356073542956 -3.31761066642946 0.000968696544893235 DRAM2 other 7.74017939767631e-08 1 0.0515526226817197 4.58582517282513 -3.31761066642946 2.34281169618304e-18 18.6503332145826 2.13673073471306 8.72844336986013 3.36551966373439e-17 -72.3955473952482 24.0000306633813 -3.01647728749396 0.00268005210565366 C8orf37 other 2.6686968031221e-14 1 4.47243908113663e-13 8.72844336986013 -3.01647728749396 0.120559466996162 25.5338762311248 15.6839921185618 1.62802149083624 0.104114596958518 -26.1545076337696 34.7865803312298 -0.751856244124385 0.45247126177851 ADAMTSL3 other 1 1 1 1.62802149083624 -0.751856244124385 0.0124166967819266 80.5079503376176 36.0262521743121 2.23470234838978 0.0258436638743003 276.213787845785 105.915096743095 2.60787929520342 0.00936168090647667 ART3 other 1 1 1 2.23470234838978 2.60787929520342 3.48180459672678e-24 70.5969460602815 9.6969368326312 7.28033473650312 1.20443391930439e-12 -115.622506091339 20.4610442041477 -5.65086048090844 2.60486065541916e-08 WHAMM other 4.44417538726207e-20 0.000351395702416045 1.46158056107588e-08 7.28033473650312 -5.65086048090844 0.67564492972741 -54.6257900880661 333.310829916458 -0.16388843441348 0.869880521074402 -721.606479079584 831.381944320226 -0.867960248607035 0.385803082035193 CXCL13 other 1 1 1 -0.16388843441348 -0.867960248607035 2.45649384794486e-10 26.5190074240206 11.4660972618826 2.31281898437921 0.0211183060056479 -175.93624595246 32.2767687104994 -5.45086305046481 7.72350276860991e-08 N6AMT1 other 2.08163288674848e-06 0.00102660798800363 1 2.31281898437921 -5.45086305046481 6.94178191263027e-11 64.3166442323417 11.8537712291338 5.42583815640598 8.82150462390063e-08 -88.8370233362963 33.368060951465 -2.66233700140721 0.00799799970799471 RWDD2B other 6.03935026398834e-07 1 0.000904116008903576 5.42583815640598 -2.66233700140721 4.41844385948047e-14 180.615901041963 29.0384546982683 6.21988679902908 1.01668280413728e-09 -256.74952700692 81.742502666721 -3.14095505558148 0.00177888853217496 USP16 other 4.40342115035823e-10 1 1.13197463412645e-05 6.21988679902908 -3.14095505558148 4.18055709843808e-24 1063.93479790384 102.716677484014 10.3579557279724 5.30486919003662e-23 -103.701396019372 289.144803688692 -0.358648658721955 0.720002117413343 CCT8 essential 5.33021030050856e-20 1 7.49153627016971e-19 10.3579557279724 -0.358648658721955 0.0306286958625351 -8.37073296190219 3.36156982321994 -2.49012616191447 0.0130779578786068 -14.9873952271055 9.46273254187012 -1.58383375634788 0.113833719005686 MAP3K7CL other 1 1 1 -2.49012616191447 -1.58383375634788 0.122219104676212 -14.0533651288308 35.0122776693871 -0.401383916280269 0.688300193860466 -204.01687368286 99.6304466144503 -2.04773621533951 0.0410809845647089 CLDN8 other 1 1 1 -0.401383916280269 -2.04773621533951 0.000459157212232963 114.163166681344 35.0009977196853 3.26171178306545 0.00117881114800874 -132.824390897717 103.014070358695 -1.28938105673548 0.197829113916286 TIAM1 other 1 1 1 3.26171178306545 -1.28938105673548 3.99566490153013e-30 243.222946583018 20.457775217368 11.8890223398549 4.34960122527358e-29 -25.677470068223 59.1624403132508 -0.434016411971295 0.664451492236788 SCAF4 other 5.4704648166849e-26 1 6.36520643306535e-25 11.8890223398549 -0.434016411971295 1.82286785256312e-07 39.9590656960268 12.3351344424979 3.23945116952735 0.00127099857330712 -87.8871738065307 26.8855115771427 -3.26894184454537 0.00114797162828815 CDK20 other 0.00129423617531982 1 1 3.23945116952735 -3.26894184454537 7.00114764577439e-19 55.5846860712313 5.84776773259496 9.50528280413859 6.33620866458654e-20 41.5544995727948 12.1532133366495 3.41921913338608 0.000675092926766432 PCGF6 other 8.06462197316752e-15 1 8.70658432600837e-16 9.50528280413859 3.41921913338608 3.08046688431272e-07 48.8299675214189 22.0718637732027 2.2123173658177 0.0273632162276611 -179.195005646824 46.3156811362704 -3.86899212643758 0.000122659653096141 ANKRD9 other 0.00214739346505439 1 1 2.2123173658177 -3.86899212643758 1.73458120437252e-19 31.3675682508623 3.77163884593746 8.31669455431799 7.24536522299119e-16 -13.4936283882171 7.8617217198814 -1.71637064615163 0.0866614196872241 SFR1 other 2.03257299259346e-15 1 9.40810674205406e-12 8.31669455431799 -1.71637064615163 2.46506287690036e-09 103.225567878564 55.3210346502908 1.86593704422015 0.0625871265230343 -592.537297064014 115.101096801126 -5.14797263911233 3.68279645537146e-07 SFXN2 other 1.97722693356178e-05 0.0047618558167953 1 1.86593704422015 -5.14797263911233 2.01285353440577e-15 322.733402475863 46.6514876224219 6.91796594114931 1.29867721898695e-11 -162.047044601497 96.6712737430776 -1.67626884727068 0.0942632795760902 C14orf2 other 2.10604865304875e-11 1 1.53594554689587e-07 6.91796594114931 -1.67626884727068 0.778115547070471 6.69343350759422 13.9121212261146 0.481122425459454 0.63062330052994 -11.4058237843349 34.738621343331 -0.328332655219909 0.74278672844695 FUT6 other 1 1 1 0.481122425459454 -0.328332655219909 0.823643125001767 -7.7601339772551 16.3606122581487 -0.474318066757557 0.63546520396463 5.93296728793827 33.9179025923895 0.174921408296912 0.861207074713484 TDRD9 other 1 1 1 -0.474318066757557 0.174921408296912 0.00131601788602118 -0.0758868904764801 2.39351696625062 -0.0317051817666264 0.97471887728377 -21.4255954418206 6.24936145851009 -3.42844554344737 0.00065337845473932 FGF18 other 1 1 1 -0.0317051817666264 -3.42844554344737 4.52748979366614e-18 175.367663044126 86.5937905309977 2.0251759620264 0.0433371188196653 -1587.63839045923 204.682311595271 -7.75659791061257 4.33066925885031e-14 PCDH1 other 5.11787446276021e-14 6.44836652642811e-10 1 2.0251759620264 -7.75659791061257 0.00135230920449839 -12.0199133313368 11.6230953700193 -1.0341404719384 0.301527477276585 -99.2905606415342 27.2175314831018 -3.64803695379867 0.000289540673587349 SH3RF2 other 1 1 1 -1.0341404719384 -3.64803695379867 0.196826769848874 0.0861898006696678 0.728436306018214 0.118321670621827 0.905857364451757 -14.4571696709136 8.05234229357795 -1.79539929424556 0.073156455122969 GDF6 other 1 1 1 0.118321670621827 -1.79539929424556 3.02703659097253e-49 712.073036723927 42.7527838180736 16.6555946334166 1.94796143834761e-50 0.810247740360801 446.87537484608 0.00181314027571978 0.998554003830338 UQCRB essential 4.56749551211846e-45 1 2.98641968113073e-46 16.6555946334166 0.00181314027571978 7.02220255068701e-60 144.402755571999 7.74721119825159 18.6393208958326 4.73062198686425e-60 281.014943691671 80.9780697079863 3.47025984572162 0.000562166749703025 MTERF3 other 1.07868053381103e-55 1 7.31023015630133e-56 18.6393208958326 3.47025984572162 1.30298630556886e-53 522.30797998955 30.3844887691687 17.1899545178308 5.12153958849559e-53 1325.42905083651 317.608259610476 4.17315674492235 3.50769988290094e-05 PTDSS1 other 1.98327545570637e-49 0.408366420367328 7.87334280939427e-49 17.1899545178308 4.17315674492235 0.0256250373975474 4.00845262961911 2.60805870986206 1.53694877130703 0.124884068258545 16.1061993261768 6.10599659452465 2.63776749247116 0.0085828818541397 PPP2R2B other 1 1 1 1.53694877130703 2.63776749247116 1.41618946066172e-29 3569.25123906394 291.809333670905 12.2314498791504 1.75258923950948e-30 5714.67882207375 3274.07328265326 1.74543399879024 0.0814877644683969 RPL30 essential 1.92941652120553e-25 1 2.58068765517771e-26 12.2314498791504 1.74543399879024 6.48805638334629e-32 192.507039966728 16.6260901625098 11.5786115728406 7.16156330588087e-28 -77.015191606286 44.8829510447814 -1.71591194013614 0.0867464639037874 SUPV3L1 essential 9.03591612508637e-28 1 1.04272361733625e-23 11.5786115728406 -1.71591194013614 7.53232627776518e-16 -3934.06385501603 2393.99756838351 -1.64330319586432 0.100907741497183 -44664.8914489482 5484.75621213264 -8.14345974943181 2.72061143952616e-15 EEF1A1 essential 7.99556434384774e-12 4.09615258335059e-11 1 -1.64330319586432 -8.14345974943181 1.25517528833946e-10 4.87896458944501 0.717339275108945 6.80147422390058 2.79791457124107e-11 14.0070021705422 9.57748524234145 1.46249269156982 0.14419783967181 FBXO43 other 1.07643832727992e-06 1 3.27607817146617e-07 6.80147422390058 1.46249269156982 1.09283695150932e-17 378.56967365044 97.5138853322397 3.88221300341602 0.000116177749648012 -1773.02678158706 264.562574826117 -6.70172938387969 5.14275277753013e-11 HK1 other 1.22332168351953e-13 7.38602153908878e-07 0.953703146860529 3.88221300341602 -6.70172938387969 1.19636212716246e-15 107.963753730911 21.3988445237687 5.04530763850313 6.1816328094093e-07 -276.534889383728 55.6482303795475 -4.96933842276075 9.01336331026635e-07 TYSND1 other 1.26180313551825e-11 0.0114749128303001 0.00602214668292654 5.04530763850313 -4.96933842276075 0.000943772898157968 226.246143435581 106.596106324992 2.12246160986216 0.0342543043653658 -392.499156904236 243.619534918714 -1.61111528693788 0.107739997159963 CD109 other 1 1 1 2.12246160986216 -1.61111528693788 0.0677980893805638 2.94612283020417 1.44396835680263 2.04029597762637 0.041805000411231 -3.65871808429288 6.49216646395803 -0.563558883556768 0.573287456007939 LRFN2 other 1 1 1 2.04029597762637 -0.563558883556768 9.33465572069387e-10 503.989440078097 117.760616006208 4.27977924344016 2.22690780524281e-05 -854.558531255883 306.279065325451 -2.79013040067832 0.00546173345140503 UBE2L6 other 7.65255075982483e-06 1 0.195143930973428 4.27977924344016 -2.79013040067832 1.88665988300776e-38 428.44324032796 56.378658129305 7.59938697627958 1.36241028990964e-13 -1140.91868286733 145.989752512798 -7.81506005202188 2.98363884868865e-14 ZDHHC5 other 2.74433546582308e-34 4.44950061504939e-10 1.69088741080685e-09 7.59938697627958 -7.81506005202188 8.34257974858501e-21 40.2296668142266 8.0651295149491 4.98809929086185 8.28318951625562e-07 -122.148009932872 20.9301910423237 -5.83597205041617 9.33010784894412e-09 MED19 essential 1.00453002752712e-16 0.000127673195804951 0.00801481417592894 4.98809929086185 -5.83597205041617 3.96556118664997e-13 157.279014838061 36.8778462439129 4.26486443372548 2.36014626686001e-05 -599.305620783446 125.775026297067 -4.76490157408474 2.42977887593112e-06 ZFAND3 other 3.80455940247198e-09 0.0303309297082481 0.206323986648902 4.26486443372548 -4.76490157408474 5.48301259099923e-21 669.963653104785 93.6774924659984 7.15181027446863 2.78842485844054e-12 -896.0942848739 185.224102673442 -4.83789243376038 1.71284412168096e-06 NPTN other 6.62402751118617e-17 0.0215116093241911 3.35670584459072e-08 7.15181027446863 -4.83789243376038 7.52051871577392e-06 55.9802043046061 155.63964593153 0.359678306703636 0.719231799605755 -1807.81412334962 398.127225038374 -4.54079502645259 6.95138774353875e-06 KAT6B other 0.0462135875084307 0.0847721735324551 1 0.359678306703636 -4.54079502645259 8.06648704716868e-06 145.007077120302 53.4373913786713 2.71358824559276 0.00687292670091858 -418.96487966555 138.253089078603 -3.03041966337077 0.00256161745490514 SAMD8 other 0.0494314326250496 1 1 2.71358824559276 -3.03041966337077 4.77755656688217e-71 2403.34292782426 116.399188122063 20.6474200258508 3.07086345405736e-67 -904.461613805367 730.914992634185 -1.2374374898861 0.216565734443537 RAB11FIP1 other 7.39804634381704e-67 1 4.76014544013431e-63 20.6474200258508 -1.2374374898861 0.134386927492014 1.51438101960502 0.876401638730833 1.72795320396489 0.0846331455134976 -0.497242875034433 2.92581153906409 -0.169950411499673 0.865120001465003 UNC5D other 1 1 1 1.72795320396489 -0.169950411499673 0.83656764799429 50.9824229764973 101.780360348391 0.500906292746322 0.616641939831415 -18.9928883064464 252.452455176652 -0.0752335258263038 0.940056876144447 GLYATL2 other 1 1 1 0.500906292746322 -0.0752335258263038 1.59263658279821e-13 291.418434857018 62.5073926282861 4.66214350980853 3.93990610237653e-06 -939.275636531666 209.44794587982 -4.48453019000061 8.91537471249858e-06 MAPK13 other 1.55520962310245e-09 0.108018680016633 0.0365071699446209 4.66214350980853 -4.48453019000061 2.68005901034415e-98 274.865981401063 10.4213595856183 26.3752516303519 3.2484149516594e-93 -130.987227084755 65.9552261446631 -1.98600224336209 0.047642092418539 BAG4 other 4.18410812694929e-94 1 5.07045089804516e-89 26.3752516303519 -1.98600224336209 0.302529429238792 -22.455010832441 15.7453388010287 -1.42613703751958 0.154413120973002 -45.0625876375346 40.6842338480184 -1.10761794865972 0.26852550134267 MS4A1 other 1 1 1 -1.42613703751958 -1.10761794865972 1.12697370490169e-54 103.062179927772 5.82882575441107 17.6814652333324 1.95723044898716e-55 152.4878600279 65.1524662498339 2.34047717308458 0.0196256167984797 TBC1D31 other 1.71739522889968e-50 1 3.01433061448513e-51 17.6814652333324 2.34047717308458 5.42221437280533e-50 72.1224107665297 4.29924860990126 16.7755850639645 4.11178046901828e-51 -33.8627267407839 48.3465926177751 -0.700415994328708 0.483970331109365 WDYHV1 other 8.19947257455622e-46 1 6.30911595166165e-47 16.7755850639645 -0.700415994328708 2.03134708623245e-38 575.0346747857 40.3194911282864 14.261952685764 2.24316926543688e-39 599.789821281916 444.267019447874 1.35006605268004 0.177562497111815 ATAD2 other 2.95378179809061e-34 1 3.38628832310351e-35 14.261952685764 1.35006605268004 2.91525083305104e-06 478.357299794741 93.7813212433736 5.10077373033962 4.69594100255777e-07 373.817885780629 1056.18018998564 0.353933816715224 0.723527146878591 FBXO32 other 0.0186517748298606 1 0.00461423162911327 5.10077373033962 0.353933816715224 2.8337818372496e-65 123.998271696924 6.23462693129031 19.8886433885245 3.3949463767191e-66 -89.30090193887 70.2713659592807 -1.27080071263473 0.204356006969722 NSMCE2 essential 4.37507577852966e-61 1 5.25979042145091e-62 19.8886433885245 -1.27080071263473 0.0403712301057234 39.1707643257363 33.9784886074593 1.15281067319566 0.249509736056242 -389.389901920296 203.709597143067 -1.91149512532207 0.0564820403350272 ZNF689 other 1 1 1 1.15281067319566 -1.91149512532207 1.04807131709894e-27 205.602731796003 19.1938353559648 10.7119149447173 2.31202529644941e-24 -258.067126985157 115.07187718572 -2.24266026849157 0.0253328656249799 PRR14 other 1.40231942227839e-23 1 3.29717927526651e-20 10.7119149447173 -2.24266026849157 1.68043992563211e-35 427.078450742636 36.6509672222827 11.6525833589184 4.4438309644939e-28 -896.001164549384 219.743543033558 -4.07748574624808 5.2557969556936e-05 FBRS other 2.4058858415275e-31 0.605467809295902 6.47732801384631e-24 11.6525833589184 -4.07748574624808 0.00908289395805007 13.0275006364045 9.12639695572112 1.42745277239314 0.154029581569834 -33.8591580077063 17.6013524518792 -1.92366797382614 0.0549235233085503 FRRS1 other 1 1 1 1.42745277239314 -1.92366797382614 8.46249165612564e-22 253.478316260623 27.5781710496845 9.19126637527776 8.98462890850934e-19 -380.005793870611 167.696437128717 -2.26603379521375 0.0238548344604158 PHKG2 other 1.03843235112318e-17 1 1.21912429659563e-14 9.19126637527776 -2.26603379521375 2.28825007122465e-16 261.179860451069 42.3251413059831 6.17079712889578 1.34093631808442e-09 -262.256428209592 80.8710992025691 -3.24289431942407 0.00125685949131175 MFSD14A other 2.46856417683715e-12 1 1.48498822749412e-05 6.17079712889578 -3.24289431942407 4.16332044168996e-10 62.2467135956477 10.3057471816401 6.04000006001908 2.8803244964847e-09 -4.89163359028841 19.6878471507872 -0.248459547294525 0.803873852745362 SASS6 essential 3.48136855334114e-06 1 3.14646647995989e-05 6.04000006001908 -0.248459547294525 0.4057201271827 35.4716753239457 26.9763284178527 1.31491857507454 0.189128207499539 7.45059284380397 158.895653960503 0.0468898466263652 0.962619375574555 COX6A2 other 1 1 1 1.31491857507454 0.0468898466263652 0.882005745773414 -0.438378624212629 0.972348511951489 -0.450845163873198 0.652292389539929 0.591038009604405 5.72697307075025 0.103202512444672 0.917842734306555 ITGAD other 1 1 1 -0.450845163873198 0.103202512444672 1.16842969415045e-11 74.6228716418721 10.547632751736 7.07484545568672 4.68166468494539e-12 1.91626079089295 47.6740572447156 0.0401950432088589 0.967952540814863 MALSU1 other 1.05509201381785e-07 1 5.60488896081662e-08 7.07484545568672 0.0401950432088589 2.36304341650158e-19 141.179876211121 16.2477263819679 8.68920813239483 4.2918723687762e-17 -266.920011272121 67.2890627866768 -3.96676666634999 8.2603748380301e-05 VPS8 other 2.7607436234988e-15 0.936643902884233 5.69488544612914e-13 8.68920813239483 -3.96676666634999 3.79235017677641e-16 53.6759212847415 12.9683918115456 4.13898053550128 4.05085868811084e-05 -115.184842063114 23.3366297110007 -4.93579593495529 1.0674230555666e-06 GALK2 other 4.06122780430985e-12 0.0135381266137512 0.346956046636694 4.13898053550128 -4.93579593495529 0.0756080445002611 9.95045727746913 6.15896187874329 1.6156062455609 0.106764619441736 33.7981496715298 18.9728606874522 1.78139449966458 0.0754110170920338 LHFPL4 other 1 1 1 1.6156062455609 1.78139449966458 7.54830912521492e-06 87.8816224542297 24.170214948991 3.63594707948174 0.000303375409541064 210.431343373208 49.1749840083786 4.27923562389677 2.21747501948829e-05 B3GNT7 other 0.0463692629561952 0.261994673552542 1 3.63594707948174 4.27923562389677 1.53612780599315e-05 164.677520694952 52.0808273122274 3.16196053698805 0.00165429450852879 -671.77172002962 265.561625109753 -2.52962648406744 0.0116991107718251 MPV17L other 0.0919065266325701 1 1 3.16196053698805 -2.52962648406744 1.21025956610362e-05 130.916814180878 34.5417012886829 3.79010903622663 0.000167472770624921 269.082432573984 60.9898369899604 4.41192247518677 1.23649093682498e-05 BUB1B other 0.0730512674100147 0.148453101875207 1 3.79010903622663 4.41192247518677 2.12923321200796e-12 56.6363985048201 9.6572952587433 5.86462327053157 7.81054397792710e-09 -51.9589964194122 19.4467072292263 -2.67186602888346 0.00776875840442931 PDE6D other 1.98508412355502e-08 1 8.39477266747604e-05 5.86462327053157 -2.67186602888346 7.90159784610032e-42 206.721946137153 13.7400059691361 15.0452588304189 5.75393029659279e-43 113.549297088046 41.4225436722368 2.74124394644919 0.00632391134137743 BRPF1 other 1.16643387404133e-37 1 8.74309708567274e-39 15.0452588304189 2.74124394644919 5.49019152933769e-33 195.721486621623 15.1674279871986 12.9040656587797 2.13978868340296e-33 177.044464139558 45.5579138467617 3.88614072046986 0.000114509702226443 RPUSD3 other 7.72030732855466e-29 1 3.18272168769357e-29 12.9040656587797 3.88614072046986 3.31911145155942e-53 487.684290759247 27.9736100783706 17.4337273377642 1.9335165781244e-54 210.524973224687 85.642099186009 2.4581949207882 0.0142732136151407 TATDN2 other 5.04903234011218e-49 1 2.97606871704908e-50 17.4337273377642 2.4581949207882 0.0771043197838208 5.02797301014619 2.24488945402957 2.23974191741201 0.0255093564831446 -0.5646662758355 6.87302997128591 -0.082156818491198 0.934552119500315 GHRL other 1 1 1 2.23974191741201 -0.082156818491198 5.9186143096567e-55 926.425473915118 52.6146094579914 17.6077611039724 2.72866134629752e-55 764.766614042844 161.086679383329 4.74754720235416 2.63399033833082e-06 SEC13 essential 9.02470309936453e-51 0.0328168856252637 4.20213847329818e-51 17.6077611039724 4.74754720235416 8.92162156720469e-08 5.51792215869089 3.71252950380907 1.4862971871414 0.137777713962468 -32.8124381793961 7.38175227346239 -4.4450744164577 1.06460065620438e-05 EXOG other 0.000647174428485028 0.128326963098876 1 1.4862971871414 -4.4450744164577 4.11811346416715e-12 98.7748516060993 13.48626627073 7.32410658541394 8.68100458134802e-13 58.4362729706947 69.1251332158262 0.845369408377728 0.398274916046983 NTAN1 other 3.79813604800136e-08 1 1.05595739727517e-08 7.32410658541394 0.845369408377728 0.262853943282684 13.2100202762625 9.54256532349334 1.38432589439446 0.166825234625249 63.2378314619097 67.0705606926943 0.942855267777683 0.346172696298172 NMNAT2 other 1 1 1 1.38432589439446 0.942855267777683 0.00972071026138624 48.9255411794612 31.2152850730247 1.5673584612476 0.117616703826303 -126.228774048025 64.9702340122632 -1.94287085412374 0.0525511396916274 ZFYVE9 other 1 1 1 1.5673584612476 -1.94287085412374 0.197670557915664 -4.79491978082893 7.4289928252787 -0.645433357333879 0.518917027537791 36.0101792679922 22.6940052021983 1.58677055668005 0.113142485169014 ATP2B2 other 1 1 1 -0.645433357333879 1.58677055668005 0.313247084369045 0.878905797293155 1.67042806999862 0.526156027355239 0.598993060125426 -5.8838626033448 4.56771897329883 -1.28814023755394 0.198241779625672 SLC6A1 other 1 1 1 0.526156027355239 -1.28814023755394 4.04946495123363e-09 463.956914578172 79.3776701987672 5.84492985768406 8.73156727855944e-09 -288.727324417482 411.639289835547 -0.701408567031662 0.483347464571699 SMG1 essential 3.20920097385266e-05 1 9.36722537643857e-05 5.84492985768406 -0.701408567031662 1.89442856145621e-23 43.8964125770935 24.1270651247737 1.81938467650674 0.0694023069081355 -517.561423282631 57.1640342457949 -9.05396951266965 2.45342317712672e-18 FCHO2 other 2.39057940170159e-19 3.75692691113415e-14 1 1.81938467650674 -9.05396951266965 6.73879917018256e-21 156.077484175585 63.2156309555977 2.46896980724931 0.0138621537755984 -826.525563164339 131.835766637106 -6.26935758214575 7.48352125385782e-10 RBPMS other 8.1317089586593e-17 1.05135990095448e-05 1 2.46896980724931 -6.26935758214575 0.299228918387874 29.7463224619425 34.2991137904283 0.867262129386086 0.386183613422475 -92.2201399275408 87.6710259551091 -1.05188845371515 0.293321205275192 TIMP4 other 1 1 1 0.867262129386086 -1.05188845371515 0.0511166293351334 9.04381341464501 7.62299574635376 1.18638573542047 0.235991709745288 45.9208761834819 19.4849307774468 2.35673796884276 0.0187923692346973 SYN2 other 1 1 1 1.18638573542047 2.35673796884276 0.103602737867189 26.4788433123331 24.5741257048794 1.07750906910497 0.281748693394292 -52.709676834519 56.7468776319352 -0.92885598352033 0.353391399693357 NRG1 other 1 1 1 1.07750906910497 -0.92885598352033 2.14988833932158e-14 173.942209784341 21.8905361686239 7.94600042888193 1.19448675727206e-14 -199.140149318417 148.200714760767 -1.34371922321616 0.179622981668054 C1orf27 other 2.16773241253795e-10 1 1.51807321981706e-10 7.94600042888193 -1.34371922321616 1.32173160534455e-11 106.364466540261 26.036952041075 4.08513509463259 5.07082364217193e-05 -235.363854592264 54.5512727654191 -4.31454377983762 1.90107211736494e-05 CPT2 other 1.19048365693384e-07 0.225581217446523 0.430360802511132 4.08513509463259 -4.31454377983762 2.47901555879442e-16 93.633947906547 38.3462969665035 2.44179895618966 0.0149305950522846 -343.651096967624 59.1267310899849 -5.81211054006387 1.04969164052547e-08 NECAP2 other 2.67138716615687e-12 0.000143387878095779 1 2.44179895618966 -5.81211054006387 2.94529586357381e-13 263.480800525519 34.9139628703836 7.5465738880367 1.90196818969239e-13 43.6809597746636 73.1499258768606 0.597142912327695 0.550661335924564 LRP8 other 2.84486127462595e-09 1 2.35425622520124e-09 7.5465738880367 0.597142912327695 5.65008324729277e-12 89.9331270685502 27.1457673835592 3.3129705194121 0.000984469011829775 -427.107889788925 83.9795382138077 -5.08585661308984 5.04457497816113e-07 PAXIP1 other 5.1856464043653e-08 0.0064898457094043 1 3.3129705194121 -5.08585661308984 0.156803255109716 -34.9981139372542 74.3196237311686 -0.470913497407502 0.637891975315876 -464.292517692367 240.995617764213 -1.92656000137988 0.054557019220149 STEAP2 other 1 1 1 -0.470913497407502 -1.92656000137988 2.41879002722293e-15 259.119940978915 44.0706373242652 5.87965041377436 7.18629265020258e-09 -383.983509458898 99.4400908712655 -3.86145573776678 0.000126295562951533 SSBP3 essential 2.52497490941802e-11 1 7.73891855500315e-05 5.87965041377436 -3.86145573776678 1.14707699264276e-05 103.344116834399 50.2694148142123 2.05580504997606 0.0402788537333782 -580.82641284852 161.712903303287 -3.59171346864759 0.000358331846614628 CLDN12 other 0.0694096288248134 1 1 2.05580504997606 -3.59171346864759 0.0123635440073107 1031.20597264557 380.888518274608 2.7073695403496 0.00699709344085438 -489.087321112875 1243.7745789043 -0.393228266124987 0.694306378815866 MMP14 other 1 1 1 2.7073695403496 -0.393228266124987 0.105187439507832 88.7828746674256 76.0463782383798 1.16748327433979 0.243525777692336 -347.765727791815 249.191152861863 -1.39557814873386 0.163409888476603 FZD1 other 1 1 1 1.16748327433979 -1.39557814873386 1.85257823433139e-15 74.4274255788798 25.0446512851033 2.9717892547839 0.00309141251601959 -572.09964864112 83.0015848957999 -6.89263523533115 1.51920944901199e-11 GATAD1 other 1.94057570046213e-11 2.20027104500407e-07 1 2.9717892547839 -6.89263523533115 1.32729991871407e-06 -219.309517554194 141.750412718889 -1.54715258564443 0.122411203223793 -1610.34598647914 305.892775138854 -5.26441327601855 2.03174449652623e-07 SUSD3 other 0.00876814326302513 0.00265102021906743 1 -1.54715258564443 -5.26441327601855 2.86801386677761e-40 222.205317012737 20.0199518904627 11.0991933561336 6.32877290178051e-26 -406.361262502094 66.2340007882941 -6.13523655019662 1.64567868231417e-09 ZFHX2-AS1 other 4.20536873285601e-36 2.29440521888242e-05 9.11280010127376e-22 11.0991933561336 -6.13523655019662 9.25058890252839e-59 110.353599652974 16.0477183819074 6.87659124037154 1.70016046083668e-11 -343.560790245274 35.0575132251035 -9.79991900849549 5.59086142534173e-21 DDX19B other 1.41904033764785e-54 8.63676272986791e-17 2.00346908704994e-07 6.87659124037154 -9.79991900849549 0.000422121463869788 -18.0640039344319 15.741917331855 -1.14750976984729 0.251679130405646 -128.560321311949 34.3894665843704 -3.73836334438459 0.000204984120157112 ST3GAL2 other 1 1 1 -1.14750976984729 -3.73836334438459 1.18913682816018e-42 142.762232321798 16.9172160558329 8.43887267565959 2.95456278951844e-16 -191.360550862682 36.9569998360604 -5.17792439082038 3.1713549354482e-07 FUK other 1.76075490145677e-38 0.00411007599634086 3.86338630357432e-12 8.43887267565959 -5.17792439082038 0.00430177560810391 -18.0116391933837 30.9442750616295 -0.582066930232205 0.560764973860565 -200.918175570888 67.5464296952481 -2.97451954866273 0.00306593900135552 IL34 other 1 1 1 -0.582066930232205 -2.97451954866273 2.84767564176742e-09 29.870845613296 16.9307762818159 1.76429273626266 0.0782543845290891 -246.549523535039 46.610918226859 -5.28952298976525 1.79210900713978e-07 DHRS1 other 2.27500807020799e-05 0.00234407858133883 1 1.76429273626266 -5.28952298976525 6.4476733731791e-30 -164.865993627089 60.3752177962714 -2.73068983673746 0.00652944804190708 -1314.56296620127 110.760111519668 -11.8685594314145 5.41700237674164e-29 CACNA1D other 8.81461426847314e-26 8.4705666165109e-25 1 -2.73068983673746 -11.8685594314145 0.301391573476506 -227.303770407103 151.490966767505 -1.50044438462095 0.134094788367786 -337.38074777884 376.617569998846 -0.895817865799181 0.370756723111101 KIT other 1 1 1 -1.50044438462095 -0.895817865799181 0.423246972581544 8.58122332047586 6.56614908930449 1.3068882847107 0.191888360302662 10.3906944958504 14.7953275759493 0.702295670204771 0.482841710337044 HYDIN other 1 1 1 1.3068882847107 0.702295670204771 4.66415974277355e-21 48.141573667849 9.62382395292599 5.00233315814263 7.69391743312272e-07 -152.997609845667 23.6005077251884 -6.48281009998676 2.04810340940104e-10 AASDH other 5.64316687278172e-17 2.91158380680452e-06 0.00745617538443923 5.00233315814263 -6.48281009998676 2.00289535123109e-11 13.6835651717076 4.28360741355222 3.19440225274062 0.00148343969579287 -31.8341870074731 9.37202041267446 -3.39672617063674 0.000732489404824583 ZNF19 other 1.78878583818448e-07 1 1 3.19440225274062 -3.39672617063674 0.00422855971831362 -9.33345045391575 6.42729698550992 -1.45215795612956 0.14703418223612 -39.7228372454014 11.9700584149634 -3.31851657430051 0.000965509000612647 CACNA2D3 other 1 1 1 -1.45215795612956 -3.31851657430051 6.39388133453649e-14 59.0892894582338 24.456577875239 2.41608984542595 0.0160177068986636 -281.427680929676 44.6411812851256 -6.30421670815971 6.00932879899824e-10 RNF111 other 6.33761517879257e-10 8.46233681474932e-06 1 2.41608984542595 -6.30421670815971 3.74433849355515e-16 241.30950694545 42.2443380218971 5.71223312388915 1.84038705437317e-08 629.949334795522 77.1096087737993 8.16953094190215 2.19300765212624e-15 CCNB2 other 4.01093539429628e-12 3.30376602792817e-11 0.000194915392928663 5.71223312388915 8.16953094190215 0.0519338869804289 12.6228508553753 6.52698657207363 1.93394772855569 0.0536388494918804 24.723619449145 11.9068917150532 2.07641255508256 0.0383256151124809 FAM81A other 1 1 1 1.93394772855569 2.07641255508256 0.00841524985937551 86.4670467236153 54.5983595321799 1.58369312676239 0.113845781466297 304.696304922584 99.6013623730612 3.05915800409769 0.00232913594435533 MYO1E other 1 1 1 1.58369312676239 3.05915800409769 5.54113287375198e-26 124.197165831447 60.7576663931915 2.04413982965884 0.041419812200496 -1007.31850194279 113.661408176643 -8.86244960450698 1.10923884018851e-17 APPL1 other 7.26220874433934e-22 1.69391863285188e-13 1 2.04413982965884 -8.86244960450698 0.0259826130776392 34.7062379887774 15.2662810680841 2.27339178638173 0.0233886907004293 -21.6523685243512 36.1071399632416 -0.599669997302309 0.548974044739427 AFAP1L1 other 1 1 1 2.27339178638173 -0.599669997302309 2.68786775016991e-20 185.415931572165 21.0894257581438 8.79189095514211 1.99462067997682e-17 -168.018104131698 64.5719952460538 -2.60202745000304 0.00952326333670626 DSCR3 other 3.20232563755243e-16 1 2.65882936640911e-13 8.79189095514211 -2.60202745000304 2.90250949600351e-15 236.4156093136 35.9500572994388 6.57622343531818 1.14599225556135e-10 -423.208636923994 110.065583498955 -3.84505876832982 0.000134970585456696 DYRK1A other 3.02238313818845e-11 1 1.31823489157222e-06 6.57622343531818 -3.84505876832982 0.68277912514352 1.84132964290793 7.81125791616588 0.235727671864117 0.813733869121406 -18.6876638187667 24.0155419062218 -0.778148745997072 0.436824041187105 KCNJ6 other 1 1 1 0.235727671864117 -0.778148745997072 0.00405005158089753 2.88714913008886 4.36883934132527 0.660850377989193 0.508991672620213 44.5510554006629 13.3528587975894 3.33644323481543 0.000907289273333791 KCNJ15 other 1 1 1 0.660850377989193 3.33644323481543 0.00959172254487898 -40.4556618944613 15.3964624663112 -2.6275946168142 0.00884449699483806 -96.6471284620953 46.8187162718363 -2.06428403335426 0.0394695867629695 ERG og 1 1 1 -2.6275946168142 -2.06428403335426 0.557604091457447 55.4979102239891 57.1121173139228 0.971736171484221 0.331618492799675 114.977173976353 173.372986238398 0.663178136749933 0.507500513776347 ETS2 other 1 1 1 0.971736171484221 0.663178136749933 0.0319081027865588 -64.0233770177253 29.3771151087936 -2.17936229546791 0.0297402040337751 46.5225284185418 76.4379756470962 0.608631089778333 0.543027313318457 TSPAN18 other 1 1 1 -2.17936229546791 0.608631089778333 7.80222854240432e-08 13.3967850933497 4.30262685984175 3.11362930826923 0.00194652954880074 -54.3994400272541 12.8913996463025 -4.21982418665121 2.87037752786087e-05 LCA5L other 0.000568470371599578 0.336379542490015 1 3.11362930826923 -4.21982418665121 1.05855609245308e-11 3023.09518662596 424.514342641967 7.12130282291928 3.40836277722379e-12 3754.58951489042 1248.91688049249 3.00627653732238 0.00276700167470645 MX1 other 9.58099119279281e-08 1 4.09446620427894e-08 7.12130282291928 3.00627653732238 0.00682639818520345 90.4300156120858 133.829461573486 0.675710822929899 0.499520655839668 -1026.1652832114 379.40184843878 -2.70469236624445 0.00705791200169865 CREB3L1 other 1 1 1 0.675710822929899 -2.70469236624445 0.000526459877144605 120.869787226389 33.0075700068436 3.66188081101787 0.000274732515962023 -76.133679141876 104.592252150216 -0.727909358262333 0.466981108794538 C2CD2 other 1 1 1 3.66188081101787 -0.727909358262333 7.45601799003459e-15 381.301653684018 63.1485253952536 6.03817193350769 2.92413282655958e-09 -811.048067571766 177.365459723184 -4.57275091124041 5.99078329297622e-06 SLC38A10 other 7.65956728116254e-11 0.0732972335895641 3.19344545988571e-05 6.03817193350769 -4.57275091124041 6.81103847784828e-14 9.27239545783247 2.16565115547337 4.28157389725387 2.192413505867e-05 -23.8926443843871 4.80646330732436 -4.97094076386231 8.93304053391488e-07 C9orf43 other 6.74497140461315e-10 0.0113762271199406 0.192230816194418 4.28157389725387 -4.97094076386231 0.00289141398631691 96.1346173035759 33.6674249862486 2.85541936583632 0.00446178674172828 -65.2176996321833 75.3592886620518 -0.865423503725621 0.387187169224402 ZNF618 other 1 1 1 2.85541936583632 -0.865423503725621 0.788912674397136 10.7255323021822 15.5994002265951 0.687560556584505 0.492020979164058 9.24308056359083 49.6826916685198 0.186042266495144 0.852480586606457 DGKI other 1 1 1 0.687560556584505 0.186042266495144 9.53846678496021e-21 211.914776442909 43.0098701057763 4.92711965699352 1.10860902938971e-06 -660.846720007733 97.490625583705 -6.77856682169234 3.16156085022323e-11 TMEM268 other 1.14700063089147e-16 4.55675765342674e-07 0.0106426466821412 4.92711965699352 -6.77856682169234 0.0241876638195953 7.93932917433693 2.90806752913674 2.73010481867789 0.00653548379745645 6.18411637373678 8.595887039572 0.719427366281991 0.472184886189456 SVOPL other 1 1 1 2.73010481867789 0.719427366281991 2.5892053164791e-06 1101.893038246 217.15826492137 5.07414736733586 5.37498903553481e-07 1034.47976727163 486.044976489571 2.12836222430092 0.0337625579684006 SNX22 other 0.0166408225690112 1 0.00525888927236725 5.07414736733586 2.12836222430092 1.19908057877079e-12 82.0649110544368 27.7183624835524 2.96066952379069 0.00320337152632454 -464.478470625539 82.6991878682602 -5.61648164387604 3.10987659206019e-08 UBN2 other 1.12965381325996e-08 0.00041849609299354 1 2.96066952379069 -5.61648164387604 4.51267113768029e-10 106.960470386258 30.2341914655711 3.53773212384588 0.000438131551051746 -426.672915616601 99.8595309547463 -4.27273102063696 2.2803145248114e-05 BRAF og 3.76853166707681e-06 0.269077113927745 1 3.53773212384588 -4.27273102063696 0.000575261661143367 560.173573981622 254.726427603275 2.19911840028655 0.0282919305401735 1791.51737804682 461.691966627926 3.88033040975693 0.000117178778683514 SLC34A2 other 1 1 1 2.19911840028655 3.88033040975693 0.00234549299983531 61.6889798358415 40.7740106128011 1.5129485402271 0.130884318725521 336.622620656099 97.6104948332678 3.44863143283001 0.00060792078745269 ACAN other 1 1 1 1.5129485402271 3.44863143283001 1.79700301567576e-10 179.608044636687 28.5977023971902 6.28050610997108 7.07493404260087e-10 -96.8683514425035 97.4344067870517 -0.994190395741975 0.320587306556272 PSMG3 essential 1.53320297297456e-06 1 7.92109615409594e-06 6.28050610997108 -0.994190395741975 2.20758442549323e-27 -16.4873868181345 25.8372624303212 -0.638124370281031 0.523659772572158 -547.736821119994 52.2857205075979 -10.4758395944912 1.58211434741762e-23 WDR19 other 2.94204776385483e-23 2.45765642727853e-19 1 -0.638124370281031 -10.4758395944912 3.7864695522357e-11 128.19555532611 24.8729035492348 5.15402454210272 3.57334240895488e-07 -241.651365715698 81.1585751563203 -2.97752104753257 0.00303535038162801 SLC37A3 other 3.338151557251e-07 1 0.00353689431638354 5.15402454210272 -2.97752104753257 6.53077928348797e-152 583.712511209259 16.1947802786128 36.0432498105653 2.2389380539854e-146 -559.994438070306 101.137134423315 -5.53698145852558 4.79077146319671e-08 AP3S2 other 1.02285065137989e-147 0.000640813590917191 3.50662478015194e-142 36.0432498105653 -5.53698145852558 3.93389610586934e-06 255.978990376427 51.7731383657966 4.94424325927162 1.02519249917403e-06 323.185506761539 126.479257303206 2.55524513388606 0.0108873302904147 FMNL2 other 0.0248307522202473 1 0.00985927626455669 4.94424325927162 2.55524513388606 4.21860850556451e-06 49.1301614678562 10.3275058916366 4.75721456694037 2.52025737373187e-06 84.918483441001 31.030610476783 2.73660369990261 0.00641139055326995 GAREM2 other 0.0265223916744841 1 0.0236727775114635 4.75721456694037 2.73660369990261 8.75458395204104e-16 167.067729467145 34.267423218421 4.87540975585627 1.4292960828466e-06 -402.455716769653 76.2517232992206 -5.27798847496692 1.89371700638272e-07 SPPL3 other 9.27548169718748e-12 0.00247376252543775 0.0136183330773624 4.87540975585627 -5.27798847496692 0.00154420001283479 67.6289584338015 20.6136100878436 3.28079158117404 0.00110159711645514 140.012924966858 62.1131885921429 2.25415774234732 0.0245840654884717 DPYSL5 other 1 1 1 3.28079158117404 2.25415774234732 2.40087794054839e-21 48.069475494673 8.05201835306211 5.96986660821415 4.29127328018232e-09 -67.1371469458236 15.4378770187698 -4.34885877534822 1.63468462650906e-05 RAB28 other 2.91994775129496e-17 0.195001529096266 4.65603150899782e-05 5.96986660821415 -4.34885877534822 3.96106730603407e-14 117.940305529837 51.8464016445828 2.27480214226516 0.0233083190041346 -639.10694704965 105.11652763601 -6.07998534029493 2.27209962710458e-09 FAM213B other 3.95512570507502e-10 3.15730964182452e-05 1 2.27480214226516 -6.07998534029493 3.51791605174445e-08 -47.2057255991729 44.8079899995411 -1.05351134026892 0.292576988830623 -528.063664226462 91.6591002629328 -5.76117006071041 1.40303815212724e-08 TNFRSF14 other 0.000263245658152037 0.000191023644412123 1 -1.05351134026892 -5.76117006071041 2.86947499279454e-21 64.1258747432056 10.3545796539803 6.192996421497 1.16881886509193e-09 -100.099424588258 21.1812994667786 -4.72583963723553 2.92561923370221e-06 PANK4 other 3.48440348375041e-17 0.0363683726941521 1.29773958591157e-05 6.192996421497 -4.72583963723553 4.5981304715482e-31 52.8514173285236 7.92630294326007 6.66785230224697 6.40888759383302e-11 -143.8012446566 17.5244998915923 -8.20572601478865 1.67821456093902e-15 C12orf43 other 6.35553593777392e-27 2.52974062915947e-11 7.42085094489925e-07 6.66785230224697 -8.20572601478865 5.65774432275364e-21 171.653745633152 32.6284191193895 5.26086614877233 2.06938734299606e-07 -375.411830229797 66.6562106700989 -5.63206078557061 2.86528026998615e-08 PEX10 other 6.8322920441573e-17 0.000386067863577934 0.00207683713743085 5.26086614877233 -5.63206078557061 5.08836607721506e-26 482.260074516839 73.213690328051 6.58702043778917 1.06497074475849e-10 -854.589594243767 149.567380159767 -5.7137431526239 1.82667260472952e-08 RER1 other 6.67288327365983e-22 0.000247660271749228 1.22620731551493e-06 6.58702043778917 -5.7137431526239 0.0433399831558122 -3.13641224783319 9.03250375771668 -0.347236196293157 0.728548917616469 -77.5421568980732 31.0711585630662 -2.4956313341417 0.0128700683924318 RADIL other 1 1 1 -0.347236196293157 -2.4956313341417 1.05494118810699e-09 283.392940130122 63.0125576414233 4.49740418001736 8.42279710821447e-06 -316.694248581773 128.72760710961 -2.46018904330375 0.0141978977100485 SKI other 8.62414421277467e-06 1 0.0763695013801806 4.49740418001736 -2.46018904330375 1.45371989211044e-15 251.146495357941 35.5270010144847 7.06917240933302 4.81234812510294e-12 -350.408449818712 123.361409419011 -2.84050296984294 0.00467324921846201 WIPI2 other 1.52858646655412e-11 1 5.75989947093571e-08 7.06917240933302 -2.84050296984294 5.30062514136769e-17 98.1126159246981 38.482578111766 2.54953334050923 0.0110604364556828 -428.635856276243 67.9866247391397 -6.30470857938441 5.98389375484932e-10 LDLRAP1 other 5.82167659276414e-13 8.4271175749543e-06 1 2.54953334050923 -6.30470857938441 1.66060549871092e-07 108.687089267115 52.0103141755434 2.08972183671644 0.0371041115996405 -434.053658365805 101.562568800085 -4.27375620264386 2.26748764537283e-05 AGAP1 other 0.00118284929673179 0.267654241659809 1 2.08972183671644 -4.27375620264386 0.000103267255647443 133.712710567727 31.0436766362235 4.30724466481859 1.96579281881568e-05 60.8317017280516 95.1301855922353 0.639457406178096 0.522798100067613 KRTCAP3 other 0.560018327376083 1 0.172871820486651 4.30724466481859 0.639457406178096 2.41702665946673e-22 97.1156049123662 23.6467502814532 4.10693240113153 4.62494109064822e-05 -259.452497142313 41.4170903074339 -6.26438253427339 7.60281256966636e-10 PAFAH2 other 2.9963879497409e-18 1.06796708166103e-05 0.394091230334135 4.10693240113153 -6.26438253427339 0.0416672231067998 83.9105303730621 33.9602550915056 2.4708451142951 0.0137847710816819 45.6792103992277 59.1912362071863 0.771722527289975 0.440613880208104 EXTL1 other 1 1 1 2.4708451142951 0.771722527289975 0.172599785596019 7.56585731196227 11.1473427962489 0.678713972491111 0.497608269844323 34.0684463867955 18.4286876335845 1.8486637282141 0.0650498106921858 SLC30A2 other 1 1 1 0.678713972491111 1.8486637282141 0.000134295918316682 26.9139308196955 11.5084379615067 2.33862587691891 0.0197166802529058 -67.7310333598603 25.3852445164919 -2.66812609647537 0.00785546283067964 WDR66 other 0.71834886707593 1 1 2.33862587691891 -2.66812609647537 1.29897355150253e-25 324.845258934436 37.5658440159415 8.64735685950737 5.92746327627839e-17 -267.497909676885 87.0277038212217 -3.07370984102255 0.00222014548293146 MRPL17 essential 1.69269243496294e-21 1 7.84736863146496e-13 8.64735685950737 -3.07370984102255 0.228921090858246 24.1240292547491 16.0663268722465 1.5015273526161 0.133832072090244 -33.834393572193 60.1269307737683 -0.562716126314467 0.573873070503981 DUSP2 other 1 1 1 1.5015273526161 -0.562716126314467 0.0127303930330481 32.4797772711393 12.0981586884899 2.68468765433208 0.00747994622672148 5.32752249120549 20.4786846944536 0.260149641966429 0.794846240881342 GRHL3 other 1 1 1 2.68468765433208 0.260149641966429 1.85671117184628e-05 160.488931550788 69.7848763151239 2.29976665468427 0.0218385075761553 -270.863600206419 114.681178096895 -2.36188365607445 0.018533001394604 UBXN11 other 0.110177240937358 1 1 2.29976665468427 -2.36188365607445 4.35203214725986e-12 43.2365450992742 7.65572579124563 5.64760889799834 2.63107776803254e-08 -44.798697920392 16.7647599583889 -2.67219441444941 0.00776293822854113 PTPDC1 other 4.01039762369997e-08 1 0.000276947245863105 5.64760889799834 -2.67219441444941 0.000454283798838143 89.8309695923169 22.7350614146825 3.95120857400909 8.79429920278355e-05 60.3104904148204 71.6467490237489 0.841775673517708 0.400281392452832 GALNT14 other 1 1 0.730278605799146 3.95120857400909 0.841775673517708 1.4837912592926e-07 117.988219999853 20.7387974597534 5.6892507981153 2.08818084308476e-08 77.4710600612017 74.4768675924864 1.04020298604794 0.298708540024453 NCK1 other 0.00106091075039421 1 0.000220616306071905 5.6892507981153 1.04020298604794 0.54344526922474 -29.6684137911417 34.4266956675201 -0.861785112276471 0.389186184541848 -69.9980300401104 75.5624818205571 -0.926359594783283 0.354670669276421 HPD other 1 1 1 -0.861785112276471 -0.926359594783283 2.53050562651555e-10 206.937957173484 34.1503724290493 6.05961055339637 2.65045638951555e-09 -565.238768125058 233.696187506369 -2.4186905835152 0.015924899153574 RHPN1 other 2.14207301284541e-06 1 2.89880415321316e-05 6.05961055339637 -2.4186905835152 1.78827614298114e-23 222.266489170231 42.6580619103143 5.21042164638261 2.68711192743595e-07 -442.914508792798 75.8558094181721 -5.83890030559337 9.0866413264039e-09 TPRG1L other 2.25734097528509e-19 0.000124405206399796 0.0026787818804609 5.21042164638261 -5.83890030559337 0.120988196487777 0.86937115007719 2.02111500769352 0.430144324676165 0.667261631812139 -7.93667598072392 4.44551695213924 -1.7853212722324 0.0747682888951944 LRRC43 other 1 1 1 0.430144324676165 -1.7853212722324 0.00245078846255238 29.937585936735 10.7272303911384 2.7908029235082 0.00544269198930009 -22.9305589922609 22.2424124720828 -1.0309384839006 0.303028635709166 AAED1 other 1 1 1 2.7908029235082 -1.0309384839006 0.860626699111822 21.2561715985179 43.9189272931313 0.483986584113185 0.628589449760008 48.7301920126715 138.110608483571 0.352834532754001 0.72434866023415 XDH other 1 1 1 0.483986584113185 0.352834532754001 1.54314441241791e-16 6.98096601730534 7.46075538124718 0.9356915835697 0.349847941816153 -84.8028608316779 11.9444232964325 -7.0997869656048 3.93082337821705e-12 XKR8 other 1.67076245532487e-12 5.73625055583214e-08 1 0.9356915835697 -7.0997869656048 0.00768405342483253 33.8790753151602 54.3777584888488 0.623031847149562 0.53353673902557 -594.582427922422 204.525739425208 -2.90712762898897 0.00380333612494342 CNNM4 other 1 1 1 0.623031847149562 -2.90712762898897 9.77112217114219e-12 52.9143187311406 36.4091954032777 1.45332293518293 0.146711780368056 -317.029102187655 58.4834344627308 -5.4208359187538 8.93651552757284e-08 EYA3 other 8.85947647257462e-08 0.00118489259380088 1 1.45332293518293 -5.4208359187538 0.233647048501795 6.35382175642516 3.91721043781354 1.6220271688982 0.105373731975821 -5.18838368539376 14.3671623604345 -0.361127935721111 0.718143242514686 DZIP1L other 1 1 1 1.6220271688982 -0.361127935721111 7.62578238060961e-12 119.736265505884 17.118304140928 6.99463361090822 7.86796289064474e-12 6.59069708294679 35.6467863175967 0.184888955324799 0.853385295409075 FANCC other 6.95395095287791e-08 1 9.36208904357817e-08 6.99463361090822 0.184888955324799 2.60158311113282e-05 280.08822918461 64.2453479317129 4.35966553535236 1.55661142516052e-05 473.348126561924 235.199827193924 2.01253603035875 0.0446530613840025 MRAS other 0.151880422027934 1 0.137978036726229 4.35966553535236 2.01253603035875 2.73964809827301e-15 283.096967520974 161.056107160018 1.75775369536097 0.0793580876452278 -1541.10695187036 252.083432371069 -6.11347972127671 1.87426453428136e-09 WASF2 other 2.85443935359065e-11 2.60972593753337e-05 1 1.75775369536097 -6.11347972127671 0.0413843950867608 25.3014447789452 47.5241116873888 0.532391745591729 0.594687477194807 -226.57514647175 108.741265074011 -2.08361698125859 0.0376943038708927 ABHD3 other 1 1 1 0.532391745591729 -2.08361698125859 1.5523039685932e-07 27.8364870229949 4.94458143102341 5.62969533646316 2.88810961330072e-08 23.8331899450193 18.1019285530078 1.31661054098345 0.188520569409393 ESYT3 other 0.00110881072476612 1 0.000303309271588842 5.62969533646316 1.31661054098345 1.19150076443545e-08 47.7862283504806 8.32654924590351 5.73901948324998 1.58027066215486e-08 -50.9645141239085 30.698560220985 -1.66015975202218 0.0974564727294116 FAIM other 9.16978988309524e-05 1 0.000167808941614225 5.73901948324998 -1.66015975202218 5.4164012174978e-06 -2.35959356123177 42.6540963533808 -0.05531927207373 0.955904456641118 -280.592378507584 66.1806276063814 -4.23979627658484 2.62944612536187e-05 FAM46B other 0.0337008483752713 0.308854741885006 1 -0.05531927207373 -4.23979627658484 0.133977601318164 -859.313467564624 590.714412284172 -1.45470205177801 0.146327447046487 -3406.67276700574 2210.86098576379 -1.54088058405392 0.123926245576076 CLSTN2 other 1 1 1 -1.45470205177801 -1.54088058405392 0.00940235399765461 122.492974892395 101.027900042956 1.21246680214388 0.225882200413306 -428.556657242683 221.581524993778 -1.93408117962324 0.0536433030460242 COLEC12 other 1 1 1 1.21246680214388 -1.93408117962324 6.91862402701477e-05 8.14237749902813 13.1184342541371 0.620682113527404 0.535069224691662 -75.6503060228897 21.5778298166493 -3.50592745728853 0.000492643089954964 RNF207 other 0.38412200597986 1 1 0.620682113527404 -3.50592745728853 0.00340150502869508 -4.73601875663127 24.7195652966588 -0.191589888405983 0.848135083796568 -123.729038632774 40.6599265415107 -3.04302169622604 0.00245548365387474 GPR153 other 1 1 1 -0.191589888405983 -3.04302169622604 9.56543815757956e-05 26.8691215185328 6.28423885312222 4.275636580106 2.25723312921547e-05 52.3893901885706 37.7671150935079 1.38716950073786 0.165967682632973 SLC13A3 other 0.521316379588086 1 0.197711049787983 4.275636580106 1.38716950073786 0.000930327179121539 25.5416083729949 7.89773182917675 3.23404351090221 0.00129526209080821 -12.9209882789716 17.0124678060001 -0.759501115670857 0.447884883152604 RHBDL2 other 1 1 1 3.23404351090221 -0.759501115670857 0.00293684149925782 348.994557396486 117.310130090969 2.97497374801184 0.00306347925473389 -421.670768000918 420.985441366592 -1.0016279105332 0.316979550495949 AUTS2 other 1 1 1 2.97497374801184 -1.0016279105332 0.52482181589027 20.5481061925241 50.0765195773056 0.410334151933282 0.68172635322195 -179.004987622482 198.184797387212 -0.90322259821344 0.366817319469228 HIST1H2BD other 1 1 1 0.410334151933282 -0.90322259821344 0.00371091606202317 23.3047830255407 7.94920851082454 2.93171112492599 0.00351307297556384 47.8462161299554 18.4425965432557 2.59433187825454 0.0097334702568201 CDC25C other 1 1 1 2.93171112492599 2.59433187825454 0.0134672475247234 128.402528659395 43.5709338685525 2.94697674019951 0.00334998500751066 147.529744034354 177.566034017589 0.830844394597108 0.406434957212052 HIST1H4H other 1 1 1 2.94697674019951 0.830844394597108 2.19928034988918e-06 34.9732475448695 7.9295493177341 4.4104962518681 1.24353899387697e-05 -48.5304029800203 25.7620659336091 -1.88379313619827 0.0601260473468169 MITD1 other 0.0142341278188989 1 0.111172386052601 4.4104962518681 -1.88379313619827 1.16928565368543e-12 836.085032838377 118.794228344745 7.03809473312143 5.91683421017519e-12 -618.354033033103 382.501138712285 -1.61660703838643 0.106544981537607 EIF5B other 1.10205172859852e-08 1 7.06055826300206e-08 7.03809473312143 -1.61660703838643 0.00039914926125414 2.48965083566898 2.01563324135301 1.23517055811095 0.217301198723639 -15.1426432858638 4.58015804364054 -3.30613990643599 0.00100841258355884 CATIP other 1 1 1 1.23517055811095 -3.30613990643599 1.05779909291406e-52 415.779041269102 25.0391642530392 16.6051485212265 2.15414855177391e-50 -182.925185175295 94.5412563749418 -1.9348715279373 0.0535241160484809 CNOT11 other 1.60774884132008e-48 1 3.30230972986941e-46 16.6051485212265 -1.9348715279373 0.000553442694915843 31.7467067849285 8.14804979505962 3.89623377169067 0.000110088348796574 32.4226882294276 56.7263645540493 0.57156294933258 0.567858142905084 KCNB1 other 1 1 0.906247287293395 3.89623377169067 0.57156294933258 3.65087679993366e-07 121.788094103679 22.2270052673538 5.47928488965433 6.5244542374469e-08 76.930414046817 81.9641225128558 0.938586441095015 0.348357363112429 TSPAN33 other 0.00253334341147396 1 0.000673845633643516 5.47928488965433 0.938586441095015 0.00319931034812732 -5.36092065831461 4.49981590917986 -1.1913644394603 0.234031022348441 27.6027623236441 10.7180184215724 2.57536059726185 0.0102769920378709 NRG2 other 1 1 1 -1.1913644394603 2.57536059726185 4.08336593983127e-05 23.6010641603823 27.6279359646476 0.854246375501303 0.393343132017231 -409.903083582162 101.884782647602 -4.02320221852886 6.55098294079809e-05 AHCYL2 other 0.233731866395942 0.748646330474406 1 0.854246375501303 -4.02320221852886 3.98294482274093e-16 336.301670433226 39.193411887235 8.5805663309133 1.03931545974068e-16 642.727519719381 271.913816971657 2.36371776497984 0.0184510417333565 B4GALT5 other 4.26414072722643e-12 1 1.36929811820835e-12 8.5805663309133 2.36371776497984 0.0452024271701602 -2.39951698931952 0.993902902565197 -2.41423682648127 0.0160991249271756 -5.72528026850478 9.38826035930903 -0.609833989406549 0.542227831236922 CD1D other 1 1 1 -2.41423682648127 -0.609833989406549 0.996842041628409 -0.235795740724009 4.44458080168906 -0.0530524139946788 0.957709729936436 2.50869525581412 41.9828553136821 0.0597552319171713 0.952372647928438 CD1A other 1 1 1 -0.0530524139946788 0.0597552319171713 1.72003192380496e-47 133.759299971311 8.32632768656931 16.06462116391 1.32887433022275e-47 -68.5240415912701 59.5536177993609 -1.15062768851644 0.250404302044179 SPATA2 other 2.58486397509409e-43 1 2.0301213142813e-43 16.06462116391 -1.15062768851644 0.10429508729502 -3.73133262647031 1.75138600631281 -2.13050270643984 0.0335797258444553 -0.159647272730529 16.5597911845193 -0.00964065735803318 0.99231153486624 CD1C other 1 1 1 -2.13050270643984 -0.00964065735803318 5.22398191112427e-47 66.6988393738228 4.40837625884693 15.130024176128 6.20523672018051e-43 -34.7799349145455 19.914454918459 -1.74646682808814 0.0813366643073178 FAM86C1 other 7.83962965402419e-43 1 9.42761614897025e-39 15.130024176128 -1.74646682808814 6.62260434672794e-07 15.7663974997681 2.91768116386146 5.40374242910825 9.7698462330958e-08 20.6945204346636 15.6022676275982 1.32637901929448 0.185269728018273 DNAH3 other 0.00449277478882024 1 0.000998673681947053 5.40374242910825 1.32637901929448 0.0954768603487543 -3.36895363450014 1.90400705615781 -1.76940186413937 0.0773870264845714 24.6313116517947 19.3970692106769 1.26984707763153 0.204682015040021 CD1E other 1 1 1 -1.76940186413937 1.26984707763153 0.0772298012351329 -5.1297037041971 4.67183336303007 -1.09800656521492 0.272710754927912 29.7223049085929 17.7974463296106 1.67003200111593 0.0955159790162496 NCF1 other 1 1 1 -1.09800656521492 1.67003200111593 2.97967976126473e-05 83.4839966421926 26.8873379578098 3.10495582616588 0.0020034708227944 -209.506255201433 85.8919407862804 -2.43918408739575 0.0150432132170213 PPP1R9A other 0.172910816546192 1 1 3.10495582616588 -2.43918408739575 6.11585190199387e-63 250.163804526691 24.8649731698874 10.0608917941505 6.38410316258117e-22 -354.779335340524 53.4668426882853 -6.63550188308121 7.95295273631336e-11 ZC3H18 essential 9.42575095135295e-59 1.13846518420326e-06 8.92497622128848e-18 10.0608917941505 -6.63550188308121 7.53276210390375e-05 81.6159714184442 22.7611527624311 3.585757376628 0.000366473330111742 -75.8585930254563 51.0216040496611 -1.48679357378926 0.137650813578589 ZFAND2B other 0.41633576148276 1 1 3.585757376628 -1.48679357378926 7.79137222593156e-16 145.100739066563 17.9834849027022 8.06855511329507 5.09383032135842e-15 -60.6181351463633 82.7878924938866 -0.73221014958002 0.464375343868889 GDPD5 other 8.26664593171338e-12 1 6.51348083192101e-11 8.06855511329507 -0.73221014958002 0.181322929624743 10.3239467133565 6.50208186115943 1.58779094662392 0.112922210689416 -9.78423580306101 20.6484063946991 -0.473849439808238 0.635799867669324 DYNC1I1 other 1 1 1 1.58779094662392 -0.473849439808238 1.00849249939357e-17 369.828257693009 54.0960390557209 6.83651269387898 2.22790588731491e-11 -1003.65810600632 213.799697428776 -4.6943850626387 3.40492547017418e-06 TMED4 other 1.13021754407037e-13 0.0421768117990476 2.61689825524009e-07 6.83651269387898 -4.6943850626387 1.70383534631165e-15 252.070004373691 29.6202603527526 8.51005363800815 1.73600223485823e-16 -55.4438422978163 241.131739966306 -0.229931747291185 0.818232201171951 PPP1R15B essential 1.78749366181555e-11 1 2.27850293325143e-12 8.51005363800815 -0.229931747291185 2.32153842176241e-10 91.8542457808798 47.6870598905191 1.92618806845632 0.0546016181094292 -879.168654812067 157.944443995795 -5.56631580428036 4.09043168288776e-08 COPG2 other 1.97028965854975e-06 0.000548363271407933 1 1.92618806845632 -5.56631580428036 6.69311231118673e-81 254.635450961925 11.4180700310049 22.3010938162476 4.06605053515511e-77 -79.9939652316145 59.1995207879778 -1.35126035087533 0.177219482447969 EMSY other 1.04124748225132e-76 1 6.32636802764783e-73 22.3010938162476 -1.35126035087533 9.77253976347729e-35 762.994061041172 63.9965527417172 11.9224243862092 2.03465628441145e-28 -676.263080482327 279.630723889994 -2.41841479746827 0.0160137242051225 GPAT4 other 1.39112103533099e-30 1 2.97019124398383e-24 11.9224243862092 -2.41841479746827 0.106174697349696 3.04021914050879 2.32122410543007 1.30974822008645 0.190833862470022 -12.9014624176373 9.4337747327662 -1.36758220151546 0.172007610636302 PKD1L1 other 1 1 1 1.30974822008645 -1.36758220151546 3.18436725586748e-08 18.4315423682112 5.96192246823193 3.09154345203642 0.00209338922958569 -81.5010749125822 20.9126548168217 -3.89721322455074 0.00010946706496832 ZSCAN12 other 0.00023885938786262 1 1 3.09154345203642 -3.89721322455074 2.54979433736209e-18 2686.12246274794 287.396436337605 9.34640142716505 2.3409855835692e-19 23.5875433620636 2822.34434528361 0.00835742931279115 0.993334883310292 TAGLN2 other 2.90115599705058e-14 1 3.19755220859717e-15 9.34640142716505 0.00835742931279115 1.54400621881109e-15 168.198206807078 20.3596580883514 8.26134732111789 1.11444185999596e-15 322.480372130378 186.450456489568 1.72957673690877 0.0842763081332598 ELK4 og 1.62166973161728e-11 1 1.44141910171877e-11 8.26134732111789 1.72957673690877 0.0249860793851127 19.9405756068234 14.325908946289 1.39192393875915 0.164516331370578 324.102585653272 139.687842772962 2.32019178777099 0.0207009342031654 SLAMF8 other 1 1 1 1.39192393875915 2.32019178777099 5.49630925559127e-08 25.5931642571675 7.63031281806054 3.35414351513739 0.000851993995201629 325.669694570959 69.8245198726975 4.66411649037778 3.91187405585209e-06 SLC45A3 other 0.000406177253988195 0.0482999089676057 1 3.35414351513739 4.66411649037778 1.34904342771155e-09 139.246769474355 21.6173987206062 6.44142115682136 2.61745597024287e-10 177.383865670511 208.344124728694 0.851398453887289 0.394924746378004 DUSP23 other 1.09731192410058e-05 1 2.97604743816614e-06 6.44142115682136 0.851398453887289 5.78101976281174e-10 37.0057813266513 10.8227061318196 3.41927248840764 0.000675957182401316 -53.3177643413273 23.2669475004159 -2.29156679621915 0.0223197868056843 RNF166 other 4.7965120972049e-06 1 1 3.41927248840764 -2.29156679621915 5.28696044850346e-05 -447.211019207897 346.688058463837 -1.28995218695871 0.197611343893704 -2528.00728428087 582.576116691062 -4.339359633621 1.70179358909195e-05 NBL1 other 0.29770874285523 0.202700634396742 1 -1.28995218695871 -4.339359633621 7.13024266812676e-42 1395.90900609469 92.9253635276906 15.0218299192203 7.18213794240261e-43 1021.47235687547 1044.78369425144 0.977687881707734 0.32866650518887 F11R other 1.05263772509555e-37 1 1.09103857483038e-38 15.0218299192203 0.977687881707734 2.97535651772096e-33 231.125049598835 17.6671916718799 13.0821612110943 3.83058317078296e-34 228.623324568069 199.842990918067 1.14401472634986 0.253127219713987 USF1 other 4.19019458390643e-29 1 5.71025033268616e-30 13.0821612110943 1.14401472634986 1.16676110329862e-14 40.482757931979 14.7694808016056 2.74097366561309 0.00633370754738736 -138.952288936359 31.8501596815501 -4.36268735622228 1.54618045590662e-05 SPATA2L other 1.18881288815096e-10 0.184567561021573 1 2.74097366561309 -4.36268735622228 1.64826173566709e-44 181.051022920023 11.6624914263574 15.5242148783789 3.62527466270069e-45 232.122779730837 131.865101231843 1.76030486885778 0.0789253708799501 NIT1 other 2.4567341170118e-40 1 5.5231059486245e-41 15.5242148783789 1.76030486885778 1.51582580597513e-55 231.669198462448 12.9163301139544 17.9361472197246 1.02221358424332e-56 84.41668033753 145.996654650456 0.578209689390758 0.563364950855247 DEDD other 2.31345334507924e-51 1 1.57635556826162e-52 17.9361472197246 0.578209689390758 4.36514888819307e-26 120.7140229814 18.8060879179002 6.41888007268651 3.05967514101003e-10 -136.193446746362 40.5639295301584 -3.35750131517966 0.00084320978337968 ZNF276 other 5.72794837108695e-22 1 3.47364918758868e-06 6.41888007268651 -3.35750131517966 0.243506686020866 2.73798998037021 2.40742956537619 1.13730844704583 0.255913758296405 -1.22654808908022 4.87105248309291 -0.251803505163923 0.801288749512426 NPM2 other 1 1 1 1.13730844704583 -0.251803505163923 0.375187799768616 -5.62073965702286 4.12853913065104 -1.36143548096552 0.173937648233052 -6.7516204882921 6.76903424637312 -0.997427438324699 0.318998904640228 CDA other 1 1 1 -1.36143548096552 -0.997427438324699 1.69785065853325e-47 439.68506832133 27.0289882018762 16.2671671258049 1.02823574648694e-48 5.95407523564659 302.088033691092 0.0197097354797413 0.984282204822104 B4GALT3 other 2.55169975470962e-43 1 1.57412610429685e-44 16.2671671258049 0.0197097354797413 6.40816743405733e-23 100.550048964779 31.8592061912115 3.15607515018738 0.0016884202691029 -380.081648144864 64.5865696341778 -5.88484030499946 7.0054087651459e-09 DMTN other 8.01982154372275e-19 9.62052785717487e-05 1 3.15607515018738 -5.88484030499946 2.59631951418369e-06 142.626869558237 27.8027004191727 5.129964622425 4.04720397505977e-07 -73.0044169200527 310.649228676091 -0.235005949414969 0.814293202468489 ADAMTS4 other 0.0166839491981444 1 0.0039949950437815 5.129964622425 -0.235005949414969 9.11949057647133e-47 296.954370583431 39.7317739232116 7.47397715383526 3.22918510038286e-13 -506.842497512654 80.6452618323579 -6.28483913371449 6.84801582862016e-10 FAM160B2 other 1.36765000175341e-42 9.62899505662281e-06 3.97477111137074e-09 7.47397715383526 -6.28483913371449 5.70783140482498e-56 726.817622746198 40.5623276630198 17.9185383241413 1.08095322412094e-56 790.690210235362 453.216975755872 1.74461737430875 0.0816204091333293 NDUFS2 essential 8.71871247087016e-52 1 1.6668298715945e-52 17.9185383241413 1.74461737430875 0.77054706490703 -10.1240961803154 15.6218355549642 -0.648073406271278 0.51721292960123 -54.1809872608668 174.548194689311 -0.310407033182478 0.756371213315591 FCER1G other 1 1 1 -0.648073406271278 -0.310407033182478 0.615927063630904 -37.6795705914254 38.8911687480455 -0.968846445205352 0.333055538546866 -71.706892230822 434.544536744375 -0.16501620931206 0.868992977766804 APOA2 other 1 1 1 -0.968846445205352 -0.16501620931206 0.764501358178437 -1.00910977454188 12.0059771249827 -0.0840506161253691 0.933047280062317 97.827103337906 134.149273828496 0.729240647720343 0.466170058030302 MPZ other 1 1 1 -0.0840506161253691 0.729240647720343 1.23246761340196e-81 671.579414100172 67.4351106167069 9.95889838332659 1.59820050922245e-21 -1375.89913902539 136.96396588066 -10.04570165721 7.64943237420583e-22 CCAR2 other 1.91784285321479e-77 1.18428512017455e-17 2.22773168980517e-17 9.95889838332659 -10.04570165721 0.608570061132289 -26.7997591448677 32.1446734557571 -0.833723172884427 0.404806995339555 -50.2285388673879 62.128005208704 -0.80846855936638 0.419178248112678 CACHD1 other 1 1 1 -0.833723172884427 -0.80846855936638 1.33732946442643e-05 76.6757996180811 32.027097747846 2.39409141039756 0.0169979664454346 -219.116320671946 75.4783302138123 -2.90303614363541 0.00384501725016174 CDC42SE2 other 0.0804537405798943 1 1 2.39409141039756 -2.90303614363541 1.28259211746516e-12 47.9465874578836 23.2559988037319 2.06168687324621 0.0397102933560308 -325.927622218694 54.8074624488306 -5.9467745386495 4.88466648788734e-09 RAPGEF6 other 1.2074322193817e-08 6.73610886010759e-05 1 2.06168687324621 -5.9467745386495 6.18587870209889e-08 275.064016058236 83.4633613456418 3.29562590846456 0.00104625897501133 -357.611585506429 134.836246340825 -2.65219178975433 0.008231375411626 EPB41 other 0.000454692669144142 1 1 3.29562590846456 -2.65219178975433 3.70532668900123e-25 133.083111640552 11.926468587244 11.1586351539877 3.71725321758627e-26 69.7535780599253 35.5403079167999 1.96266105018614 0.0501995121128884 MIS18A other 4.79543380090539e-21 1 5.35916396379413e-22 11.1586351539877 1.96266105018614 2.67269322750227e-111 541.960109916439 19.0977749804184 28.3781807290184 1.4872025266885e-106 -94.1965965454156 94.6502464434362 -0.995207092267935 0.320113110865899 ALG8 other 4.1792903998453e-107 1 2.32524115047748e-102 28.3781807290184 -0.995207092267935 5.1952483070174e-07 229.997812143214 66.7726606596739 3.44449075221764 0.000619269666239863 -447.975290907433 155.080764682491 -2.88865799588109 0.00403339728632871 FBXW5 other 0.00355043269301569 1 1 3.44449075221764 -2.88865799588109 1.46686201814195e-33 322.001809316176 27.8483109924128 11.5627051638394 8.70042143867787e-28 -316.966118381437 85.5988641162817 -3.70292435131913 0.000234994513799377 C21orf59 other 2.07018236620374e-29 1 1.26617233197079e-23 11.5627051638394 -3.70292435131913 6.73963274236414e-09 53.1123649990789 11.9494524826611 4.44475301911497 1.06873680240148e-05 -122.174829179721 36.9216799026803 -3.30902682385403 0.000998746644978797 SYNJ1 other 5.27443658417417e-05 1 0.0960794385358926 4.44475301911497 -3.30902682385403 2.79888150254501e-21 167.486797472581 17.1878625048812 9.74448087567707 9.01546172108753e-21 -46.6316187479152 53.5577312641506 -0.87067950130159 0.384317501312491 PAXBP1 essential 3.39924158484091e-17 1 1.24900206683947e-16 9.74448087567707 -0.87067950130159 1.55054305829923e-10 156.766298731577 22.8389766066796 6.86398087932401 1.85072162009201e-11 104.865330467387 71.3319615139838 1.47010299789428 0.142118416210799 IFNAR2 other 1.32633453206916e-06 1 2.17811427468628e-07 6.86398087932401 1.47010299789428 6.44075466032109e-79 257.157764115098 15.0758170081489 17.0576336908372 2.41300255707966e-52 -379.879618139933 41.6432432209482 -9.12223901784956 1.51940207808218e-18 MRPL10 essential 1.00147294213333e-74 2.32893950528436e-14 3.70613062741865e-48 17.0576336908372 -9.12223901784956 1.18843259737455e-06 217.580934774013 50.5878495307429 4.30105127599437 2.02029792937505e-05 -343.475385129066 158.857865343512 -2.16215536061963 0.0310479445169157 IFNGR2 other 0.00787811968799587 1 0.177483173095599 4.30105127599437 -2.16215536061963 1.1664487545567e-22 504.912617914069 47.9326168409204 10.5338003887787 1.06693353583973e-23 229.594700890088 146.430210153169 1.56794626361546 0.117487133217856 GART other 1.45386172767947e-18 1 1.51547239430676e-19 10.5338003887787 1.56794626361546 2.05331900524072e-24 243.435202524454 22.229159112487 10.9511655970696 2.56893507162204e-25 74.8898595759827 67.6859284697893 1.10643173949233 0.26903787917388 DONSON essential 2.63050697761389e-20 1 3.68565114725614e-21 10.9511655970696 1.10643173949233 0.301784560760082 9.41863619099279 7.14830005602385 1.31760504136305 0.188230980776505 -77.1003573516586 85.3228525385241 -0.903630798288736 0.366620345656173 SV2A other 1 1 1 1.31760504136305 -0.903630798288736 8.65419699861264e-06 294.53490867449 67.3156107366312 4.37543246583386 1.45271371407611e-05 1102.95070978096 483.344999685656 2.28191190660556 0.0228791769562073 LAD1 other 0.0529031062525191 1 0.129160776318507 4.37543246583386 2.28191190660556 0.0113614480540904 362.704279864153 347.227567477159 1.0445722455145 0.296685504332764 -1025.80189294432 700.473387416431 -1.46444092148569 0.14365221106013 STC1 other 1 1 1 1.0445722455145 -1.46444092148569 0.722965354973567 138.81684260833 180.37154445379 0.769616088993981 0.441860477445483 -282.201878816527 1300.12013315474 -0.217058309936148 0.828243985162209 TNNI1 other 1 1 1 0.769616088993981 -0.217058309936148 0.236606910137567 268.5122519352 205.10247564602 1.30916143790783 0.191032372893402 -1558.18625047064 1488.32716438336 -1.04693799035525 0.295593115424841 CSRP1 other 1 1 1 1.30916143790783 -1.04693799035525 0.000202770141743584 21.0161549551505 10.2992987701136 2.04054231499091 0.0417960872081674 169.9330223826 42.6325168199232 3.98599555124519 7.67128303831432e-05 HOXB13 other 1 0.871918030134806 1 2.04054231499091 3.98599555124519 0.780951833373197 111.755390605152 159.901159025031 0.698902942833939 0.484910281723485 109.72701954693 251.620191172605 0.436081933789088 0.662949650784188 C1QC other 1 1 1 0.698902942833939 0.436081933789088 2.81115045653132e-16 5.21728799078429 0.606746639072665 8.5987917440437 8.85678334609441e-17 0.285636926235389 1.8406236718621 0.155184859676622 0.876733895863858 KCNE2 other 3.02339231599943e-12 1 1.16909540168446e-12 8.5987917440437 0.155184859676622 2.52920012607857e-76 547.285405092364 25.1579344148015 21.7539880686855 3.60335473994428e-75 -8.97709702578734 119.367321032179 -0.0752056504926274 0.940079900859404 ATP5G1 other 3.92607735571176e-72 1 5.60393729156134e-71 21.7539880686855 -0.0752056504926274 0.00353064955575252 438.338096015542 139.723929401666 3.13717269398749 0.00179957172018317 -229.514559010899 424.04715665525 -0.541247725421005 0.588561725256688 RCAN1 other 1 1 1 3.13717269398749 -0.541247725421005 3.77359184296742e-108 963.278564738475 35.3555764408156 27.2454492815576 2.82279442099895e-102 -564.028805698905 168.012323032524 -3.35706807404669 0.000845283350436433 UBE2Z other 5.89963348729527e-104 1 4.41174540057926e-98 27.2454492815576 -3.35706807404669 0.116762900962574 13.4146712058565 6.459622069567 2.07669598335428 0.0383248938913029 -12.8392365046966 78.5985532831181 -0.163352071614457 0.870305318665089 CIART other 1 1 1 2.07669598335428 -0.163352071614457 3.12757968340051e-107 428.556845929558 15.6406777579783 27.4001454771327 4.95635888175645e-103 -177.596470716321 74.4675881898474 -2.38488280651117 0.017441211642384 SNF8 essential 4.88903256109168e-103 1 7.74678893218533e-99 27.4001454771327 -2.38488280651117 0.00596209552229907 -974.042122327311 367.009661540601 -2.65399586005056 0.00819159064954455 -2489.32597782004 1049.47144339691 -2.37198067034834 0.0180465394476609 CLIC6 other 1 1 1 -2.65399586005056 -2.37198067034834 0.00147729092439562 -7.66249955221622 28.6888595359858 -0.267089723193938 0.78950167383973 -219.464945532711 62.5359737504645 -3.5094191770074 0.000486432948624759 CCDC24 other 1 1 1 -0.267089723193938 -3.5094191770074 0.0241175188097884 3.30129722578739 1.31778665166446 2.50518338580651 0.0125434776165484 9.91049045938092 6.30818530441126 1.57105252638197 0.116778693447167 IGF2BP1 other 1 1 1 2.50518338580651 1.57105252638197 6.49151743193436e-05 182.012585762269 41.2978871900587 4.40730986853206 1.26519926065639e-05 64.2871051154908 124.461225012624 0.516523158991647 0.605702501015876 CBR1 other 0.36196701200466 1 0.113058205932255 4.40730986853206 0.516523158991647 2.75158294573237e-05 98.5713093703073 23.9576113260088 4.11440473046228 4.49385494901295e-05 -84.1718377180637 72.2020872469514 -1.16578122499662 0.244222365992582 CBR3 other 0.160252190759453 1 0.383370765700294 4.11440473046228 -1.16578122499662 0.03932267650784 -14.9201564045143 9.72130517047776 -1.5347894282575 0.125420145420068 -74.6235326329221 33.2678860918286 -2.24311014011953 0.0252936841701661 C2orf81 other 1 1 1 -1.5347894282575 -2.24311014011953 0.531550426305693 13.0630011940918 12.9792543620818 1.00645236079621 0.314646293702605 1.3242642782842 23.7188637722111 0.0558316912227349 0.955496425288814 ACTC1 other 1 1 1 1.00645236079621 0.0558316912227349 4.912344795351e-09 84.5693650593229 22.1718597353827 3.81426574354355 0.000152511568982448 -275.312498035587 67.5278534227311 -4.07702131907116 5.25490638307916e-05 MORC3 other 3.8738751056138e-05 0.60541776439455 1 3.81426574354355 -4.07702131907116 1.32096970255351e-13 172.155747504503 21.7626859158675 7.91059284548061 1.47935060510642e-14 85.1374892826673 66.5602543916124 1.27910402477963 0.201414929192039 CHAF1B essential 1.29428611456193e-09 1 1.87596450233545e-10 7.91059284548061 1.27910402477963 0.680587509085416 -0.231534431719123 1.52840262516189 -0.151487852681879 0.879647890528314 3.78001199651324 4.64728919554444 0.813379980771866 0.416361391443708 CLDN14 other 1 1 1 -0.151487852681879 0.813379980771866 0.000160669753077298 85.0645143477481 20.3187770127552 4.18649775497554 3.31308115051334e-05 83.6931806597715 62.1393154596344 1.34686357647661 0.178595483909891 SIM2 other 0.850585672791215 1 0.286283342215858 4.18649775497554 1.34686357647661 8.58057888941709e-17 181.272961294278 26.6291697650251 6.80730803452848 2.67192774928503e-11 -339.853887933881 81.2496981614855 -4.18283262121682 3.36331629482141e-05 HLCS other 9.36741797357664e-13 0.391981075352664 3.13043055106235e-07 6.80730803452848 -4.18283262121682 0.000285005360583141 -76.3413862577661 38.7329067061219 -1.97096971928781 0.0492328955766438 -314.179050893169 77.1750379921197 -4.07099314839663 5.3749294361384e-05 SCUBE1 other 1 0.618976873865698 1 -1.97096971928781 -4.07099314839663 3.77983535589349e-05 78.6975940083313 17.2833346229736 4.55338022002559 6.55240268731472e-06 66.312245716094 41.9112566987124 1.58220609305021 0.114197936741794 ARHGAP27 other 0.217038146135404 1 0.0598496461459327 4.55338022002559 1.58220609305021 5.57432442350967e-21 406.215644829949 40.535036880105 10.0213463732982 8.63261536122297e-22 136.92124439144 88.7450156334212 1.54286123467508 0.123451324697282 ADPGK other 6.73266903871498e-17 1 1.20571738750201e-17 10.0213463732982 1.54286123467508 4.3252333640268e-07 914.793032323727 266.919075662553 3.42722988251404 0.000656962656567137 -3366.08957036109 993.098109089238 -3.3894834151362 0.000752188745651415 PTMS other 0.00298051831115087 1 1 3.42722988251404 -3.3894834151362 1.26165513565374e-28 801.385667710495 66.684422360652 12.0175843074163 1.15378475285562e-29 -536.485057152323 523.158768311434 -1.0254727429761 0.305596786225569 ADIPOR1 other 1.70411759172751e-24 1 1.69364063871676e-25 12.0175843074163 -1.0254727429761 3.40749644586042e-06 267.272989773791 53.1977096321694 5.02414467881841 6.87349507816097e-07 -355.582887012095 417.351568221382 -0.851998444686514 0.394590559391948 CYB5R1 other 0.0216512324169971 1 0.00668241191498809 5.02414467881841 -0.851998444686514 1.28230322056675e-25 508.802101396187 45.8327515372325 11.101277674391 6.53234040197635e-26 733.523458641844 541.734848139567 1.35402671834925 0.176299515091211 PSMD4 essential 1.67135401768671e-21 1 9.40461047672535e-22 11.101277674391 1.35402671834925 6.01301162947985e-08 82.2019426809234 101.688557666406 0.808369639292072 0.419229891171232 -724.889191315172 161.355863096782 -4.49248745848412 8.5969681781247e-06 ATP13A2 other 0.000442557655929717 0.104238239159762 1 0.808369639292072 -4.49248745848412 0.408177460659001 -8.23671001355939 6.84881172303691 -1.20264804270412 0.229636692041908 -17.9421944546101 23.5530510929742 -0.761777927784575 0.446523287834942 M1AP other 1 1 1 -1.20264804270412 -0.761777927784575 1.00328974305405e-25 982.017082963457 87.4798662776872 11.2256353918768 2.05602063849129e-26 828.289218785935 1059.2770328406 0.781938240051106 0.434595499401095 PSMB4 essential 1.30929311468554e-21 1 2.96971621023682e-22 11.2256353918768 0.781938240051106 0.130063745302101 15.6902854737592 8.61175923303337 1.82196053665477 0.069016040446376 8.28584688372833 19.3729401821844 0.427702083721298 0.669039175054182 IRX6 other 1 1 1 1.82196053665477 0.427702083721298 0.00925534037137807 650.315822631645 291.5694325185 2.2303978061568 0.0261303798078557 -5083.49467296777 2348.21225612429 -2.16483610444911 0.0308367968548053 BTG2 other 1 1 1 2.2303978061568 -2.16483610444911 4.28205715653438e-06 694.28233114632 159.047907536468 4.36524027194213 1.51971821712991e-05 -983.795471788663 542.379282087328 -1.8138514952167 0.0702503988756869 HK2 other 0.0269041651145055 1 0.134876861566764 4.36524027194213 -1.8138514952167 0.857385478189559 -65.4534736847693 205.339284730291 -0.318757678399149 0.750032621043621 -390.259593192752 754.868393697479 -0.516990241545538 0.605373092767454 C1R other 1 1 1 -0.318757678399149 -0.516990241545538 0.0576815103697827 12.5045665319581 5.28546195925212 2.36584174256878 0.0183387479844079 -35.3713873329229 66.4108121238785 -0.53261488907775 0.594517675263537 CELF3 other 1 1 1 2.36584174256878 -0.53261488907775 0.000248518097418754 136.271495454134 78.4100294373981 1.73793450189853 0.0827840933422199 -286.925183999353 127.680601970201 -2.2472104577508 0.0250236673877096 ALDH4A1 other 1 1 1 1.73793450189853 -2.2472104577508 0.1611351632561 -30.3574132772536 16.67860638788 -1.82014087815597 0.0693189937014375 -41.0651973695689 28.4931642895783 -1.44122979645995 0.150128693688513 STARD9 other 1 1 1 -1.82014087815597 -1.44122979645995 3.46138393106476e-12 57.4531237681196 7.85633067794994 7.31297168147098 9.34170231107238e-13 89.5161341187334 99.6982102553772 0.897871023857275 0.369649339054331 THEM4 other 3.20385696659355e-08 1 1.13529708186463e-08 7.31297168147098 0.897871023857275 0.798191104844261 -1.97866308677491 3.04810548378659 -0.649145214068139 0.516517978090676 9.30735655236805 43.5314735017589 0.213807523698732 0.830777120644703 TCHH other 1 1 1 -0.649145214068139 0.213807523698732 1.26877005429932e-23 56.8671639992426 41.6654981774477 1.36485021148801 0.172885885903207 -616.395274834587 71.8894575825966 -8.5742095651005 1.12814264334593e-16 UBR1 other 1.60562850371579e-19 1.71297178965646e-12 1 1.36485021148801 -8.5742095651005 1.04698367853106e-14 259.573113923433 223.392346158156 1.16196064183713 0.245760051320131 -2705.38985655828 478.791569436976 -5.65045424617567 2.58147833039652e-08 AMFR other 1.06792335210168e-10 0.000348318871120402 1 1.16196064183713 -5.65045424617567 1.43882628754225e-24 193.29051605192 22.9858424869609 8.40911165912528 3.69864735275587e-16 -204.860249106949 51.1242709573509 -4.00710357860845 7.00989861832111e-05 MED8 essential 1.84817236634802e-20 0.799268640460973 4.82784438955223e-12 8.40911165912528 -4.00710357860845 0.00064234810466486 3.26515056749162 3.51975473632938 0.927664230064145 0.353990907669711 -22.7367440495224 7.95516257818661 -2.85811180174589 0.00442406311643836 RGL4 other 1 1 1 0.927664230064145 -2.85811180174589 3.98301907055453e-43 135.29178667307 24.5725969852473 5.50579927527789 5.67197041383597e-08 -412.748007307014 52.2093997080101 -7.90562637408928 1.49238959181603e-14 RSPRY1 other 5.91080030070292e-39 2.23216711247924e-10 0.000587616134873406 5.50579927527789 -7.90562637408928 0.00548901001478616 2.17700928771718 1.614774231294 1.34818183590447 0.178160978242128 -7.50898279814977 3.34053795484763 -2.2478363963065 0.0249863741488346 CCDC17 other 1 1 1 1.34818183590447 -2.2478363963065 9.3870802627654e-21 522.275481469656 86.0057709125555 6.07256322370121 2.36471936215226e-09 -923.752304546732 177.923041191392 -5.19186440587562 2.94593902637209e-07 GPBP1L1 other 1.12907801400542e-16 0.00382176669891251 2.59102300511024e-05 6.07256322370121 -5.19186440587562 1.64310025089519e-63 330.232981110173 28.1890988880472 11.7149179695914 2.30242744333496e-28 -352.488124387283 61.450409939466 -5.73613951045265 1.62495731518593e-08 NAE1 essential 2.53366058688038e-59 0.000220734201694857 3.36039285354738e-24 11.7149179695914 -5.73613951045265 3.86671779510693e-15 81.6461208984194 20.4940138581243 3.98390093144457 7.70048910318186e-05 -229.75547960136 42.4223944360465 -5.41590079144933 9.16028545259564e-08 TMEM69 other 4.01094636886442e-11 0.00121410423388703 0.642990840115685 3.98390093144457 -5.41590079144933 0.659884290842397 -0.507259990534649 3.24127304138611 -0.156500234339321 0.875696689055955 4.43843458577653 7.05191365858729 0.629394346082461 0.529354657390359 ADGRG5 other 1 1 1 -0.156500234339321 0.629394346082461 2.08210260581819e-06 90.8941138809837 19.5086812729223 4.65916238055225 4.03655390377098e-06 -117.165318668542 81.999674408576 -1.42885102305099 0.153646309264036 ACE other 0.0135170101169717 1 0.0373784891489192 4.65916238055225 -1.42885102305099 0.00144267456976496 -93.2984502718957 124.633056207621 -0.748585111452884 0.454432027284564 -939.645404130035 261.739686724925 -3.58999972792646 0.000360697384923743 EFCAB14 other 1 1 1 -0.748585111452884 -3.58999972792646 0.222423278266924 6.98119207276396 69.3070415940132 0.100728467298581 0.919803748770167 246.489447907743 154.43449815797 1.59607763063154 0.111061952533204 SPON2 other 1 1 1 0.100728467298581 1.59607763063154 5.69157524649081e-08 42.4878036297074 8.91407529414267 4.76637253194682 2.41282539182622e-06 -66.0675451906983 28.3983869843025 -2.32645414780838 0.0203620874450553 CHCHD6 other 0.000419924421686092 1 0.0227046869370847 4.76637253194682 -2.32645414780838 2.32262160258935e-28 703.620852232969 72.5661425070645 9.6962691955752 1.37446007188067e-20 -319.700791033515 161.696640681692 -1.97716408755123 0.0485360064950564 CTBP1 other 3.12787451220708e-24 1 1.90060338739659e-16 9.6962691955752 -1.97716408755123 0.861330258776308 -0.102328563705215 1.57435451418087 -0.0649971545693796 0.948200913339798 -1.6506347559215 3.46223184538172 -0.476754541473958 0.633734539935064 LRRC36 other 1 1 1 -0.0649971545693796 -0.476754541473958 0.356550823448328 66.1568791203109 51.2716696736855 1.29032035705802 0.197505300451235 27.9559300631189 112.753770457149 0.247937873383519 0.804279050832635 TPPP3 other 1 1 1 1.29032035705802 0.247937873383519 0.479942021106561 -14.0812078631106 11.8974137482494 -1.18355200223094 0.237124044447042 -12.6702336321273 26.1641227473491 -0.48425982993873 0.628402664428179 ZDHHC1 other 1 1 1 -1.18355200223094 -0.48425982993873 1.19196013866786e-33 320.360954391704 58.5349490524814 5.47298596099356 6.84779770838877e-08 -837.351320572737 128.617604217091 -6.51039432486545 1.74644796537275e-10 ATP6V0D1 other 1.68316691181288e-29 2.48554474431849e-06 0.000706418811597386 5.47298596099356 -6.51039432486545 1.55017919454054e-14 17.0267134101006 9.73886662000282 1.74832596794468 0.0809758619943129 -120.443427669978 19.5931454607241 -6.14722265556677 1.53359739453198e-09 ZFYVE28 other 1.57265679286138e-10 2.13936836537211e-05 1 1.74832596794468 -6.14722265556677 9.35393593516288e-07 33.5980603921656 13.83486117175 2.42850723076073 0.015496566768778 -73.6097123983663 30.4317497797914 -2.41884587416159 0.0159095068484541 CARMIL2 other 0.00626433089577858 1 1 2.42850723076073 -2.41884587416159 0.0654829410790474 -1.16911713407277 2.72218692593342 -0.429477168865577 0.667752540956524 -12.636914567431 5.97375589644888 -2.11540524696415 0.0348666694569092 C16orf86 other 1 1 1 -0.429477168865577 -2.11540524696415 0.459534062954338 -1686.59236033033 3206.07535757496 -0.526061359208364 0.599059177922965 -13925.7203930806 11291.1665844248 -1.23332875207863 0.217983823923997 PIP other 1 1 1 -0.526061359208364 -1.23332875207863 0.0583824667812787 6.66841434485641 12.292307785793 0.542486769861353 0.587704567270951 -80.8698757486858 39.9878750426097 -2.02235991941342 0.0436262149193612 FAM131B other 1 1 1 0.542486769861353 -2.02235991941342 1.92360795226118e-27 19.6081872717757 27.31205510063 0.717931594657752 0.473107657710559 -520.651318126421 53.1767230362912 -9.79096281978669 5.87492803708957e-21 RGS12 other 2.56570828672597e-23 9.07441384608855e-17 1 0.717931594657752 -9.79096281978669 8.06028944275038e-30 156.298582863142 21.1224321029033 7.39964896569173 5.38703059320045e-13 -171.899427448544 47.2734768229747 -3.63627638585283 0.000303613203871477 PSKH1 other 1.10127734656298e-25 1 6.58941582160279e-09 7.39964896569173 -3.63627638585283 0.00353710664737089 158.180435959866 116.315520447931 1.35992544546689 0.174418917507324 -935.899986958003 377.34682197896 -2.48021165793782 0.0134330266559019 ZYX other 1 1 1 1.35992544546689 -2.48021165793782 1.39524562175663e-29 200.484975357381 51.4895149742516 3.89370487287824 0.000111186483003747 -862.311895257831 95.9439591402807 -8.98766220390212 4.31502626454891e-18 ABR other 1.90102215964341e-25 6.60069567688047e-14 0.914479114236742 3.89370487287824 -8.98766220390212 6.85109467535133e-05 70.4807337916856 16.0619275422463 4.38806199357495 1.3722535721912e-05 46.7317136798812 50.1780138135572 0.931318522361584 0.352098926092924 LYPD5 other 0.380715331109274 1 0.122363851032289 4.38806199357495 0.931318522361584 0.0049951370715443 353.258284829624 161.372070206725 2.1890918569557 0.0290175408414975 -327.900045486613 310.995832918951 -1.05435510954923 0.292191881405252 CCDC117 other 1 1 1 2.1890918569557 -1.05435510954923 5.34494209272813e-15 9.08981957512247 3.42972369103631 2.65030667014926 0.00827511488320629 -75.6350209378971 11.1986156596245 -6.75396167140476 3.69219164316999e-11 ZNF230 other 5.51704922811397e-11 5.31601752783614e-07 1 2.65030667014926 -6.75396167140476 4.38672871971782e-07 65.8350112182429 17.7651855133546 3.70584428565369 0.000232621280125383 -128.918192334649 47.1776655309401 -2.73261067252472 0.00649124186151133 CCDC107 other 0.00302070139639769 1 1 3.70584428565369 -2.73261067252472 7.49782474807119e-08 6.95068495935033 2.55296270595038 2.72259557225409 0.00668419513396316 -35.5826970125396 8.65668911518201 -4.11042796375061 4.55638652272686e-05 ZNF222 other 0.000547116271866755 0.527265048409952 1 2.72259557225409 -4.11042796375061 0.0442673787518381 29.2291451460034 11.6959511219053 2.49908236118226 0.0127530158850942 18.5217494036335 31.1953511223971 0.593734282103834 0.552943159895494 NPR2 other 1 1 1 2.49908236118226 0.593734282103834 1.08630282968933e-06 5.70020961206514 1.61730522215663 3.52451073178634 0.000459866469201354 -14.3479403474406 5.28076930353632 -2.71701707132565 0.00679634809406473 ZNF221 other 0.00722174121177469 1 1 3.52451073178634 -2.71701707132565 3.75344751765e-07 8.21792647231275 2.90634817051063 2.82757811183679 0.00486258122318629 -36.0547448836724 9.76860818778254 -3.69087839235538 0.000245947872235136 ZNF233 other 0.00260113912973145 1 1 2.82757811183679 -3.69087839235538 8.25626029447566e-25 38.8309128854147 4.42765411054294 8.77008725522444 2.28243345673956e-17 -58.0803384877542 14.8819121658503 -3.90274702877443 0.00010701476710369 ZNF235 other 1.0643970771638e-20 1 3.03928839099439e-13 8.77008725522444 -3.90274702877443 5.94185575358899e-11 203.337980481238 31.8237261397622 6.38950887109279 3.62222460739213e-10 -68.3447844607296 83.2005853170023 -0.821445957385147 0.411758194349947 GNE other 5.18367495943104e-07 1 4.10325603525381e-06 6.38950887109279 -0.821445957385147 1.00594326624563e-14 429.644289146708 137.849614831302 3.11676089681134 0.00192452526040174 -2400.36327718928 394.926750029698 -6.07799617779443 2.28332259529205e-09 ARHGAP35 other 1.02726926349004e-10 3.1726767461583e-05 1 3.11676089681134 -6.07799617779443 0.193192525906924 -4.59804814422588 2.65026698263639 -1.73493771546439 0.0833161293141926 -8.55539410565802 7.73570467045969 -1.10596183154826 0.269230100095595 PTGIR other 1 1 1 -1.73493771546439 -1.10596183154826 1.95870243410664e-12 177.096658755962 46.0595996251879 3.84494568335579 0.000134865283666218 -270.326942089005 74.6448127627473 -3.62151008333583 0.000320341135497736 DFFA other 1.83021155442925e-08 1 1 3.84494568335579 -3.62151008333583 0.00738565046466488 36.4432844308921 12.8455657233026 2.83703226591118 0.0047255070358638 -1.48990694312435 23.7668031479451 -0.0626885716959862 0.950037824083052 CCDC28B other 1 1 1 2.83703226591118 -0.0626885716959862 1.07251406141918e-16 43.3890383312935 7.01048421427533 6.18916425814655 1.20147467750982e-09 -41.7930836023701 12.9707637547022 -3.22209889816389 0.00134970353277548 IQCC other 1.16807506429162e-12 1 1.3336368920359e-05 6.18916425814655 -3.22209889816389 2.51104798612345e-15 51.1038733709733 9.1554869351073 5.58177557711455 3.78258416047437e-08 -58.8018122401377 16.9394373433897 -3.47129665809615 0.000559647190061486 TMEM234 other 2.61902304952676e-11 1 0.000394977438036734 5.58177557711455 -3.47129665809615 7.27625816027545e-26 352.578179332645 66.8035018798237 5.27783977503031 1.89770743285494e-07 -861.01208823599 123.780594742887 -6.95595371814507 1.01842673944719e-11 BSDC1 other 9.5202561769044e-22 1.47855194032943e-07 0.00190814482373564 5.27783977503031 -6.95595371814507 3.69174643753958e-08 44.0495237940246 12.2823305507621 3.58641412653493 0.000365747057449933 -64.1601282902098 22.7580012667154 -2.81923388342749 0.00499087638250152 ZBTB8A other 0.000275847293812957 1 1 3.58641412653493 -2.81923388342749 1.70547348696213e-07 112.775052468259 23.0032826299765 4.9025634420236 1.25760312772631e-06 -13.9453691134039 44.6506310446909 -0.312321881844089 0.754918059768414 ATAD3B other 0.00121361493332225 1 0.0120377485927902 4.9025634420236 -0.312321881844089 3.58684094124671e-20 591.374821467111 79.3532908943738 7.45242969512484 3.70778356048843e-13 -384.885700836105 154.008256746071 -2.49912380652879 0.0127487121544713 SSU72 essential 4.26044967001285e-16 1 4.55389976899189e-09 7.45242969512484 -2.49912380652879 3.03013291268853e-20 175.751752022098 28.4366332222397 6.18046977110659 1.29046846226103e-09 -232.746733572718 55.6834775244984 -4.17981677725353 3.42171583733196e-05 UBE2J2 other 3.60555515280808e-16 0.398629895049173 1.43009714987768e-05 6.18046977110659 -4.17981677725353 3.26527379629313e-11 115.695370955285 32.3679129507867 3.57438464232131 0.000382387983241716 -249.844046213071 60.3388807765663 -4.14068081803238 4.01534866465791e-05 ZNF362 other 2.88682856330276e-07 0.465860752073611 1 3.57438464232131 -4.14068081803238 0.531390251403016 -7.4868530903925 26.6462591101952 -0.280972014098892 0.778839686155915 -54.9390227442482 49.5655552424311 -1.10841132466962 0.268178555025679 FNDC5 other 1 1 1 -0.280972014098892 -1.10841132466962 2.43772042038888e-06 115.920619436857 22.5314378801363 5.14483896028015 3.74190118247029e-07 117.530080818932 81.9735973478473 1.43375531416786 0.152215557482484 CPAMD8 other 0.0157208589910879 1 0.00370074026946311 5.14483896028015 1.43375531416786 2.95430601969708e-10 314.919687376975 53.8068675577453 5.85277868181055 8.36052539078724e-09 -329.370826734711 190.407122597111 -1.72982408558129 0.0842289074839935 NR2F6 other 2.4898891134007e-06 1 8.97586005954918e-05 5.85277868181055 -1.72982408558129 6.88076516555365e-08 14.5847096789721 2.50908792687726 5.8127535200107 1.04786794744247e-08 9.55418494894736 8.87894490395916 1.07604958159917 0.282382064328316 ANKLE1 other 0.000503396779511905 1 0.000112069476978972 5.8127535200107 1.07604958159917 4.51251542734317e-22 68.6839017823016 6.77639087754851 10.1357644538872 3.08071220895443e-22 -8.77149893566825 22.2256339107305 -0.394656862022432 0.693250255369038 CCDC58 other 5.56844403734147e-18 1 4.3200827306168e-18 10.1357644538872 -0.394656862022432 0.000374950052150039 75.4568558535156 19.5927724230719 3.85125975151224 0.000131471553615572 -15.3068794359943 63.189449951112 -0.242237896481721 0.808686958454057 KALRN other 1 1 1 3.85125975151224 -0.242237896481721 0.0189855664645618 -10.9006821157016 27.1033553261216 -0.402189396277287 0.687706791990133 -244.138159412018 87.64786107631 -2.78544343711321 0.00553678995290814 CILP2 other 1 1 1 -0.402189396277287 -2.78544343711321 1.47302699383252e-17 38.4733433729255 4.63839349939556 8.29454063738643 1.0051993360263e-15 -32.2976072305191 18.8343173450235 -1.71482760106794 0.0869927666535779 FAM86C2P other 1.64345621701894e-13 1 1.30123054048604e-11 8.29454063738643 -1.71482760106794 1.99559701588988e-05 7.83914524061379 46.1894152018407 0.169717352046089 0.865295174439908 -675.193021035892 147.215469841615 -4.58642710417806 5.59457143516445e-06 ABCG1 other 0.118039563489886 0.0685670675093756 1 0.169717352046089 -4.58642710417806 0.0810952381387045 -29.1661676596829 1000.74749239843 -0.0291443824553405 0.97676010771423 -6410.3680260556 2933.94381390934 -2.18489801872317 0.0293214941390803 TFF3 other 1 1 1 -0.0291443824553405 -2.18489801872317 0.0683425718846635 -739.493628309307 815.617969650704 -0.906666669722838 0.364983776194295 -5488.05021554982 2391.1899002963 -2.29511266121933 0.0221057079499142 TFF1 other 1 1 1 -0.906666669722838 -2.29511266121933 0.0740519296573406 -114.87641588499 107.390093160674 -1.06971148365721 0.285222725122195 -699.662564208345 314.841158131489 -2.22227159994165 0.0266746717768502 TMPRSS3 other 1 1 1 -1.06971148365721 -2.22227159994165 0.321439019652284 -2.34672765054 2.23397608621515 -1.05047124945544 0.293967070474486 5.21995616800892 6.54943346533521 0.797008809332451 0.425792987026869 UBASH3A other 1 1 1 -1.05047124945544 0.797008809332451 0.000180387157478124 12.8552677970255 10.6432834793635 1.20782912735068 0.227636862489516 -112.262910552195 31.2033228246828 -3.59778704283991 0.000350150180582868 RSPH1 other 0.947573738232585 1 1 1.20782912735068 -3.59778704283991 6.49567457832244e-19 187.773862102895 24.6493770651066 7.61779340739226 1.14884281089521e-13 -267.125468772225 72.2655251531317 -3.69644402647295 0.000240750324084462 SLC37A1 other 7.48951278880578e-15 1 1.42835626678602e-09 7.61779340739226 -3.69644402647295 0.00052588377467212 74.8963126537604 19.1401053361998 3.91305645074526 0.000102665602019069 52.5526327420418 55.9185282738422 0.939807150944371 0.347732826280504 PDE9A other 1 1 0.847607210269433 3.91305645074526 0.939807150944371 7.6861224328099e-16 69.1988676352947 8.04439227916035 8.60212496282162 8.45964591502205e-17 35.4330516975897 23.4994337552327 1.50782576578892 0.132181766131111 WDR4 essential 8.15728173794115e-12 1 1.11709624307866e-12 8.60212496282162 1.50782576578892 4.92458251800445e-24 182.589262192894 21.2854877512145 8.57811032225355 1.02914259269261e-16 -281.269542003598 62.1663725649274 -4.52446443951409 7.45398440382967e-06 NDUFV3 other 6.26997846192327e-20 0.0907075362102032 1.35620410865032e-12 8.57811032225355 -4.52446443951409 6.62794173151052e-08 5.86787348451961 8.92299330838928 0.657612673429073 0.511073084488903 -143.087050365719 26.0449577663973 -5.49384843120486 6.11964615989122e-08 PKNOX1 other 0.000485695570085091 0.000815810029575099 1 0.657612673429073 -5.49384843120486 2.74116383164841e-06 123.329133182314 25.4760494154023 4.8409834339445 1.70790967370609e-06 204.179495206642 74.0375011345799 2.7577847992938 0.00602499940964946 CBS other 0.017573601324698 1 0.0162046469841234 4.8409834339445 2.7577847992938 1.07794230724618e-16 147.210452628794 17.646632459466 8.34212720001586 6.70145337723494e-16 -54.6008697923288 51.2765380383044 -1.06483143911824 0.287450231936278 U2AF1 essential 1.17377137836036e-12 1 8.70652822770363e-12 8.34212720001586 -1.06483143911824 9.26082686648843e-09 8.95794779925794 1.51629563689446 5.90778445923962 6.27943871891718e-09 -1.81148578659981 4.39044240178508 -0.412597551869327 0.680071878122529 HSF2BP other 7.17714082152853e-05 1 6.77739820932731e-05 5.90778445923962 -0.412597551869327 6.30676782461723e-17 346.725019677674 38.849706920639 8.92477825858386 7.39597078130231e-18 156.761599334543 112.548233221959 1.39283927296655 0.164255688179766 RRP1B other 6.9103255054331e-13 1 9.92909077389836e-14 8.92477825858386 1.39283927296655 0.00469122978553562 1225.4536094368 390.585239564678 3.13748059399943 0.00179843198904603 -272.145503459399 1131.95325739967 -0.240421149619353 0.810096400201225 CSTB other 1 1 1 3.13748059399943 -0.240421149619353 9.14926554026469e-08 209.491363569235 37.388575164879 5.60308497035266 3.38555133031241e-08 -9.16855615528805 108.348707019106 -0.0846208174285946 0.932594742118737 RRP1 essential 0.000662864288392177 1 0.000354293617888476 5.60308497035266 -0.0846208174285946 4.06307754901278e-17 367.57332216811 56.9510179268062 6.45420109330648 2.4553115509096e-10 -760.006598047422 164.728903639591 -4.61368091000128 4.96459250487195e-06 AGPAT3 other 4.48035561329639e-13 0.0610247710698861 2.79439007609022e-06 6.45420109330648 -4.61368091000128 8.68726108099365e-13 161.497123797283 23.8118814918041 6.78220760727661 3.19189120876322e-11 -128.688699442536 70.0107788183272 -1.83812695151518 0.0666074184884762 TRAPPC10 other 8.22423006537669e-09 1 3.7300440665607e-07 6.78220760727661 -1.83812695151518 1.17231180692688e-05 42.2295398007554 21.4783498810736 1.96614451457314 0.0497985473966791 -226.503844363248 61.041886912886 -3.71062979567614 0.000228376137206086 C21orf2 other 0.0708310793745219 1 1 1.96614451457314 -3.71062979567614 5.78387147163635e-11 55.2000008197119 7.93017349454009 6.96075575871284 9.83391843764195e-12 22.3629742502428 22.4720058205571 0.995148115785261 0.32010911717665 LRRC3 other 5.05105495618003e-07 1 1.16718777936372e-07 6.96075575871284 0.995148115785261 0.634173172541903 -18.410687090101 89.1338704217526 -0.206550966574071 0.836437982860786 221.913386250371 255.829528617235 0.867426787868542 0.38609137466451 ITGB2 other 1 1 1 -0.206550966574071 0.867426787868542 4.2155743445018e-06 45.1904982580801 9.39213309615783 4.8115266037453 1.94262396604294e-06 -11.5872428518097 26.9571547118042 -0.429839238439203 0.667482796045129 FAM207A other 0.0265075314782273 1 0.018369452222902 4.8115266037453 -0.429839238439203 8.60827267983031e-20 275.143574353454 49.9215384925582 5.51152033093831 5.48740489292277e-08 -663.082970656111 119.021779781559 -5.57110616118385 3.97588100660722e-08 RALGDS other 1.01560401076638e-15 0.000533324678226293 0.000568659769053587 5.51152033093831 -5.57110616118385 5.18349520012965e-13 52.8175604570834 7.22039612252965 7.31505024942854 9.37618537423499e-13 -28.3431910843998 26.4261326099868 -1.07254404201728 0.28395570894615 SPATC1L other 4.94868286756378e-09 1 1.13939404667704e-08 7.31505024942854 -1.07254404201728 1.53794627989001e-19 398.645980380349 42.249442904594 9.43553223365705 1.16279572771797e-19 -39.5624278487654 137.635347324734 -0.287443804355161 0.773883207174419 LSS other 1.80431857556696e-15 1 1.59279758782807e-15 9.43553223365705 -0.287443804355161 1.73339289354996e-10 157.597204538101 47.5278845513967 3.31588931478057 0.000974220507229209 -484.749242039821 110.939405708763 -4.36949557231613 1.49091028533318e-05 VAV2 other 1.48014419180231e-06 0.178133960891608 1 3.31588931478057 -4.36949557231613 2.53332080280428e-09 491.515520524634 79.0632446287026 6.21673854687969 1.02020203430208e-09 -81.5032118457854 258.238910808661 -0.315611662047995 0.752419903885837 MCM3AP essential 2.03045662344763e-05 1 1.13568890458508e-05 6.21673854687969 -0.315611662047995 3.26563606948568e-15 80.2438475799572 9.59922053595304 8.35941285851397 5.41458210255e-16 18.1597150929789 32.558735894123 0.557752461644458 0.577245428061239 C21orf58 other 3.39593494865816e-11 1 7.04707860646882e-12 8.35941285851397 0.557752461644458 7.30946821446642e-22 318.825298610025 31.8543302577473 10.0088526749823 9.67064520999693e-22 -62.8309090121969 108.043848150135 -0.581531573411647 0.561125810397362 PCNT other 8.98552927604357e-18 1 1.35040889712397e-17 10.0088526749823 -0.581531573411647 6.51049042831144e-18 143.204717818167 17.6920283623196 8.09430749744692 3.9144763721912e-15 -171.496770215218 60.1788067841404 -2.84978681665079 0.00454380406632276 DIP2A other 7.33341641845001e-14 1 5.01679291860024e-11 8.09430749744692 -2.84978681665079 0.00199414806219402 179.935846119252 52.5782754699834 3.4222470119237 0.000668763338672695 255.129395475227 158.810519276888 1.60650186547408 0.108755916910239 S100B other 1 1 1 3.4222470119237 1.60650186547408 1.02973366996776e-12 296.97883101832 41.8521119460305 7.09591027093884 4.11535680606757e-12 -164.242742992709 126.412583363979 -1.29925944571361 0.194416620546465 PRMT2 other 9.72480477917555e-09 1 4.93472434615562e-08 7.09591027093884 -1.29925944571361 0.161563115086581 5.13465868954082 4.63633532525778 1.10748216626357 0.268572273888776 -20.6193123333092 17.8043885918437 -1.15810280296595 0.247327477330959 ZNF208 other 1 1 1 1.10748216626357 -1.15810280296595 2.9928315667459e-08 19.5841073933282 6.60146690812299 2.9666296394261 0.00314242122686707 -59.9457747689961 15.7743305942559 -3.80021037411406 0.000160806331812298 ADAMTS13 other 0.000225001077187957 1 1 2.9666296394261 -3.80021037411406 2.82316022267387e-18 140.599924612506 43.3826842363731 3.24092266505315 0.00126403623524316 -728.460753866679 103.67441180627 -7.02642765148173 6.33957163988559e-12 CACFD1 other 3.20852159306885e-14 9.23231817916538e-08 1 3.24092266505315 -7.02642765148173 0.000463587705129246 26.7132332390667 9.42779877415614 2.83345390360835 0.0047750570246452 80.5402746249548 22.5302216712311 3.57476618740049 0.000381608073053168 SLC2A6 other 1 1 1 2.83345390360835 3.57476618740049 3.38119036494859e-11 125.271807289856 17.6640390062668 7.09191183541954 4.1411072100418e-12 68.8422340836858 74.0858021023492 0.929223037749939 0.353186398856316 ZNF761 other 2.98761980646857e-07 1 4.96435932339811e-08 7.09191183541954 0.929223037749939 0.407153167603457 -5.85350601378718 8.6043488644312 -0.680296220668655 0.496607399184391 -27.1065674072446 20.4873236392725 -1.32308972535991 0.186363437784038 FCN2 other 1 1 1 -0.680296220668655 -1.32308972535991 9.66996411961874e-14 11.7051360988364 12.3298389314141 0.9493340638063 0.342878566694806 -207.397067010405 29.2426438691008 -7.0922816671016 4.1894403512674e-12 C9orf116 other 9.5162116901168e-10 6.11155558442888e-08 1 0.9493340638063 -7.0922816671016 2.02980046700616e-06 54.1787568730194 10.9294918562886 4.95711580972049 9.56789258058232e-07 2.96934531611351 38.5739276978034 0.0769780391402195 0.938669266052872 ZNF714 other 0.013187613634139 1 0.00921579413361689 4.95711580972049 0.0769780391402195 4.07375719417244e-06 92.6401513231022 18.9950624006639 4.87706485870057 1.43324753702211e-06 17.4940679783933 43.8099474857775 0.399317255152441 0.689823401764871 GPSM1 other 0.0256605965660922 1 0.0136531160376726 4.87706485870057 0.399317255152441 8.09987268590701e-19 78.6657682694161 9.38274525324974 8.38408868046055 4.41638236365656e-16 -61.5627536413708 35.5563230953254 -1.73141507000943 0.0839457460777026 C19orf47 other 9.32052349967319e-15 1 5.75498785808086e-12 8.38408868046055 -1.73141507000943 1.76926156022233e-10 56.7440062754468 16.930050231868 3.35167382838804 0.000859472291122078 -173.772941392616 38.6671269417986 -4.49407429867177 8.55394499129178e-06 CFAP157 other 1.51024166780578e-06 0.103742244854387 1 3.35167382838804 -4.49407429867177 3.22953669521809e-13 55.1516352681361 14.2271638469027 3.87650243306523 0.000118960918512352 -163.945152941916 32.3715435141701 -5.06448365275359 5.62238723087631e-07 TOR2A other 3.11359632785976e-09 0.00721914520444518 0.975479531801288 3.87650243306523 -5.06448365275359 1.02939656743132e-11 30.9907499427285 41.3602090809249 0.749289005819393 0.454008104991844 -613.185912973066 93.4404293867301 -6.56231908390767 1.2400638235482e-10 ST6GALNAC6 other 9.32324471122551e-08 1.76994309535034e-06 1 0.749289005819393 -6.56231908390767 2.62159501972286e-24 259.791182529061 26.5695276521457 9.77778701715388 6.48038144221341e-21 -206.584798787532 104.843684329124 -1.97040766078979 0.0492964827755097 SHKBP1 other 3.35406866823343e-20 1 8.98893709849422e-17 9.77778701715388 -1.97040766078979 2.42708445837517e-13 89.8550488976731 12.291788797538 7.31016863189763 9.56282621654849e-13 -81.151608828354 47.8583548160063 -1.69566231727658 0.0905209766754236 RDH13 other 2.35305838239473e-09 1 1.16197901357281e-08 7.31016863189763 -1.69566231727658 5.50330524757516e-37 159.868246174218 37.8546916692082 4.22320825041241 2.82404769727949e-05 -956.179371470898 86.0189802127699 -11.1159115012264 5.27305637170664e-26 ZER1 other 7.94237013330047e-33 8.22227680040216e-22 0.245325023462669 4.22320825041241 -11.1159115012264 1.35989777708236e-12 184.225023481964 31.5696700387621 5.83550677773217 9.22655202546057e-09 -185.288281043412 71.7372326293934 -2.58287466984741 0.0100585568929337 ZDHHC12 other 1.27871187979055e-08 1 9.88717315048355e-05 5.83550677773217 -2.58287466984741 0.062462406053448 9.82763182073434 14.0579864102835 0.699078198962075 0.484802486787054 -60.2473625608816 31.9446177352224 -1.88599416215434 0.0598291940800419 PKN3 other 1 1 1 0.699078198962075 -1.88599416215434 0.0020817601613755 11.8260673684544 8.20335055345607 1.44161428813645 0.149984504955971 -88.5193927915287 32.9662736927211 -2.68515009056282 0.0074701470035645 SPTBN4 other 1 1 1 1.44161428813645 -2.68515009056282 2.44747371168911e-06 48.0314488490179 10.1154896903251 4.74830683629261 2.63628270915071e-06 -47.1477507032833 39.0050786298323 -1.20875927852183 0.227288297720941 BRSK1 other 0.0157788630192597 1 0.0247230592464154 4.74830683629261 -1.20875927852183 0.306868187990346 -6.23282881946533 5.13147098714147 -1.21462809301342 0.22504379145483 -22.1479925390101 19.7098738252512 -1.12370037146739 0.26164411874911 COX6B2 other 1 1 1 -1.21462809301342 -1.12370037146739 0.192345455823001 9.70752757193522 7.99483789140192 1.21422444129545 0.225191786075711 -15.6058633675595 18.4631401961711 -0.845244265154627 0.39834812828978 PLPP7 other 1 1 1 1.21422444129545 -0.845244265154627 1.05509385040568e-13 50.5148905633296 7.20622679376017 7.00989463821347 7.11983641784965e-12 -18.1670139540396 16.6346686689867 -1.09211757177405 0.275266633534752 MED27 other 1.03705174556374e-09 1 8.47901319001715e-08 7.00989463821347 -1.09211757177405 4.02624955109296e-16 125.988343342921 18.5487073327735 6.79229776407726 2.9408760516728e-11 -173.164011930474 59.0857740174916 -2.9307225776413 0.0035259723492486 DEDD2 other 4.30808701966946e-12 1 3.44082498045717e-07 6.79229776407726 -2.9307225776413 1.31615235409188e-12 -100.042635512288 62.2453980434067 -1.60722942831089 0.108581090094357 -805.898638992566 114.895954023759 -7.01416029694063 6.85830055199697e-12 SIK3 other 1.23836774996505e-08 9.98019896326599e-08 1 -1.60722942831089 -7.01416029694063 2.22987612214341e-29 141.344619253283 18.3407509290457 7.7065884488644 6.13722865908984e-14 -112.861643419432 33.8334292645842 -3.33580266241509 0.000908350751958813 MPZL3 other 3.0335234765639e-25 1 7.68173872321075e-10 7.7065884488644 -3.33580266241509 0.31394525329299 -17.8733309805342 11.7316032823629 -1.52351989326171 0.128207646677454 -19.4592476209933 21.6414459445823 -0.899165779903203 0.36896073228065 JAML other 1 1 1 -1.52351989326171 -0.899165779903203 8.40000015561971e-49 54.944833725449 4.62983287180433 11.8675630950013 7.14255287450124e-29 -127.977139109698 17.7911302070517 -7.19331136472562 2.25366286920032e-12 NEK8 other 1.26630002345967e-44 3.30026390565695e-08 1.04481263448204e-24 11.8675630950013 -7.19331136472562 7.88912037850136e-19 80.5815969606053 9.4461115239814 8.5306633058511 1.65331681414003e-16 -43.6620833752974 35.7777667140867 -1.22036916737194 0.222886722921784 TLCD1 other 9.08116646769291e-15 1 2.17047431360303e-12 8.5306633058511 -1.22036916737194 0.575375785861301 104.655491312241 277.853424133887 0.376657194844616 0.706574439524062 -300.881578159231 509.567958927117 -0.590464084109076 0.555123419003406 PCSK7 other 1 1 1 0.376657194844616 -0.590464084109076 4.2824020655884e-11 161.931070252552 45.8444430980741 3.53218534918477 0.00044721268375978 -483.537134302023 108.800455549129 -4.44425652320618 1.06962299730643e-05 SAFB other 3.76508789606533e-07 0.128900267405398 1 3.53218534918477 -4.44425652320618 0.754734156737477 0.478799263480032 7.26426642909997 0.0659115780172939 0.947472304782248 -7.69250670838132 13.3744118119712 -0.575165982364615 0.565415549439946 CD3G other 1 1 1 0.0659115780172939 -0.575165982364615 6.57910352579252e-07 774.888463986031 144.714565618189 5.35459896988168 1.27133124345584e-07 -1361.96321931803 1435.20160586133 -0.948969966139812 0.343061169369183 S100A1 other 0.00446457965260281 1 0.00129001981273464 5.35459896988168 -0.948969966139812 8.81757648031571e-22 280.536570506644 27.2987400051702 10.2765391535841 9.6129841337267e-23 108.757778181226 270.603924766133 0.401907615623899 0.687911332903809 CHTOP other 1.08182845836993e-17 1 1.35427720475942e-18 10.2765391535841 0.401907615623899 4.66700984345115e-28 126.418506127374 28.8890723047652 4.37599742884512 1.45098378493504e-05 -353.960466467025 53.4805974063125 -6.61848377978752 8.75011690966141e-11 CXCR5 other 6.26826092073924e-24 1.25196672743436e-06 0.129021478156424 4.37599742884512 -6.61848377978752 1.60915447146629e-05 236.801185991885 50.3751507792791 4.70075389013601 3.31044247862343e-06 139.937102054007 548.018063108899 0.255351258424122 0.798551062764205 ZBTB7B other 0.096098705035967 1 0.0308135985910269 4.70075389013601 0.255351258424122 1.31785472893195e-29 264.615431015577 21.5903720720897 12.2561774355733 1.3818760211649e-30 -25.2607370037294 235.015848372687 -0.107485249095504 0.914444625643826 FLAD1 other 1.79649956648003e-25 1 2.03591794198225e-26 12.2561774355733 -0.107485249095504 2.14779143958938e-10 339.224989117459 49.8836959059034 6.80031787855787 2.81865035860339e-11 -560.558739757255 543.803693981167 -1.03081083479486 0.303098814673108 SHC1 other 1.82626706108285e-06 1 3.30007583985285e-07 6.80031787855787 -1.03081083479486 3.63136020934032e-38 82.4461601953148 26.9902975394325 3.05465918168787 0.00236437026832686 -485.424205966079 50.0081579010353 -9.70690036067155 1.21875137645104e-20 VPS11 other 5.27455070406681e-34 1.88126462468983e-16 1 3.05465918168787 -9.70690036067155 1.12940705126204e-21 48.2009650926856 12.9513087377682 3.72170612782347 0.000218667862045957 -136.555494367436 23.9653791100842 -5.69803188758971 1.99626797699428e-08 NLRX1 other 1.38228129003961e-17 0.000270154945326636 1 3.72170612782347 -5.69803188758971 1.49586029430202e-17 2004.66275276866 226.083831913452 8.8669001042767 1.13656389538674e-17 3342.96913189421 2420.77648120934 1.38094911192469 0.167874421875673 ADAR other 1.66833298623504e-13 1 1.52060883563792e-13 8.8669001042767 1.38094911192469 0.000360747141436674 41.1604615556406 10.8108036672937 3.80734520969654 0.000156852240136817 101.718210718721 112.610075053203 0.903278065223414 0.366787915163733 IL6R other 1 1 1 3.80734520969654 0.903278065223414 5.19302779714629e-33 349.774461572912 27.1924721444256 12.8629151375123 3.80798612962217e-33 350.648604086384 281.295590417696 1.24654852770961 0.213113732215137 UBE2Q1 other 7.30295499112683e-29 1 5.65828659000558e-29 12.8629151375123 1.24654852770961 0.802073694703928 -7.1710393576464 13.4868109917317 -0.531707559484796 0.5951513401351 -48.2348849493288 139.515835140748 -0.345730539480827 0.729682416584955 CHRNB2 other 1 1 1 -0.531707559484796 -0.345730539480827 1.72431667132649e-27 215.188052233812 18.4163739678046 11.6846048310055 2.98541145632504e-28 120.686949910785 190.037605777267 0.635068777135803 0.525655065522817 CRTC2 other 2.30179032455374e-23 1 4.35481969134133e-24 11.6846048310055 0.635068777135803 5.49008265066789e-26 199.513139557806 30.1579560351572 6.61560549147361 8.82784097362508e-11 -289.213997582964 57.6953148523013 -5.01278133802276 7.25741141661026e-07 ANO10 other 7.1958513302304e-22 0.00927860049613622 1.01855629153686e-06 6.61560549147361 -5.01278133802276 1.35857089605884e-15 502.618032986107 61.5040298696437 8.17211545408316 2.24953594692532e-15 1321.20637863901 639.305598370649 2.06662726246457 0.0392553356408958 FDPS essential 1.43043929646036e-11 1 2.8947028565035e-11 8.17211545408316 2.06662726246457 2.54842923174708e-13 228.105334544136 29.3730437138849 7.76580516360681 4.30802724329168e-14 167.188924725892 294.309471480193 0.568071845887377 0.57022998361716 RUSC1 other 2.46917308263974e-09 1 5.41174382302301e-10 7.76580516360681 0.568071845887377 4.72472147427022e-31 178.939780339619 14.2206743891348 12.5830727462782 6.3121828863212e-32 86.1206558522637 147.473951636754 0.583971982146307 0.5594895031833 GBAP1 other 6.52909260529402e-27 1 9.34013701688948e-28 12.5830727462782 0.583971982146307 8.13891791582772e-28 252.883167267523 21.3628521562204 11.8375189519761 7.84901302082789e-29 31.7117017081647 221.759527406756 0.143000402638839 0.886344521091677 FAM189B other 1.08988249810849e-23 1 1.14760419377525e-24 11.8375189519761 0.143000402638839 0.0475887744856631 20.8114878857213 8.44683453792017 2.46382094881731 0.0140582027404201 19.6119709224906 75.9278644085294 0.25829741262007 0.796276163972956 PAQR6 other 1 1 1 2.46382094881731 0.25829741262007 3.54914907150554e-15 161.43230631678 19.1824029926515 8.4156456507885 3.53411168570202e-16 4.71806940756598 172.453202685969 0.0273585490676994 0.978183885097652 PMF1 essential 3.68543639585135e-11 1 4.61519645035827e-12 8.4156456507885 0.0273585490676994 5.84103873981932e-22 154.812434635891 14.9525375389316 10.3535894314132 4.91976025453583e-23 -4.5033078874877 134.425962579284 -0.0335002837330003 0.973288041301251 SLC25A44 other 7.19265510421351e-18 1 6.94817740748095e-19 10.3535894314132 -0.0335002837330003 4.64125249797617e-09 1300.26038300934 207.614290400784 6.26286553059178 7.73991884616776e-10 1251.35613440086 1872.45757608294 0.66829612076906 0.50423119869684 LMNA other 3.66566122290158e-05 1 8.65477725378479e-06 6.26286553059178 0.66829612076906 0.21066945139842 -19.6559811902566 17.0377001725167 -1.15367573036433 0.249137889917132 19.5765526784781 31.7062732899624 0.617434679233516 0.537205462174307 CCR5 other 1 1 1 -1.15367573036433 0.617434679233516 1.23334228826382e-10 164.667576961271 66.2059256784425 2.48720299994066 0.0131894322556876 -547.556703521772 124.337467001069 -4.40379490372813 1.29343773670684e-05 NBEAL2 other 1.05808434910153e-06 0.155134922140618 1 2.48720299994066 -4.40379490372813 1.20942296774273e-08 69.7428106159705 35.2645449247155 1.97770340620759 0.0484836936679842 -269.9180195715 65.8436350806967 -4.09937907044004 4.79781233164963e-05 CCDC12 other 9.30650973678032e-05 0.554339236798798 1 1.97770340620759 -4.09937907044004 0.144115327944204 -6.46379334534638 4.51007820563346 -1.4331887498697 0.15239351520271 -15.8411809106078 8.41386697429231 -1.88274677493819 0.0602821637477001 PTH1R other 1 1 1 -1.4331887498697 -1.88274677493819 6.70541664036406e-29 374.507961421303 30.9085326584462 12.1166528854602 4.98011162342422e-30 -3.97126826687743 278.217886642419 -0.0142739502294528 0.988616743461905 UBQLN4 other 9.08785117268541e-25 1 7.32225811992063e-26 12.1166528854602 -0.0142739502294528 0.299678989536968 66.9278047972466 113.532532077281 0.589503321846899 0.555774886718657 326.710551805923 211.802895337742 1.54252165101402 0.123543715831418 MYL3 other 1 1 1 0.589503321846899 1.54252165101402 3.70961217870011e-12 68.2596986448892 15.8361313436804 4.31037714726514 1.93663625746174e-05 -228.848869105844 50.4947809936526 -4.53212915478555 7.19266517259903e-06 PPP1R35 other 3.4265687694653e-08 0.087592276471911 0.170462723381783 4.31037714726514 -4.53212915478555 2.30669696311165e-18 166.004876708034 17.7606031229717 9.34680402228692 2.34603767019669e-19 103.822855970533 159.352205634385 0.651530711841811 0.51498011419845 GPATCH4 other 2.62848118946573e-14 1 3.20421824995465e-15 9.34680402228692 0.651530711841811 0.0257811747871232 -4.48841315783149 2.16763203145613 -2.07065271812594 0.0388632455165849 35.2195056668668 20.1017433101967 1.75206225268042 0.0803275626120696 FCRL3 other 1 1 1 -2.07065271812594 1.75206225268042 0.00384173853611188 962.499311394357 2003.74038962665 0.480351305177661 0.631172865162223 -19549.5432341602 6384.80811048479 -3.06188422515894 0.0023094143107848 AZGP1 other 1 1 1 0.480351305177661 -3.06188422515894 0.491775947894202 19.0772586847355 54.0417077666316 0.35300991536235 0.724219273699696 -146.453658375181 154.632037617722 -0.947110706367598 0.344007567194052 FGFR4 other 1 1 1 0.35300991536235 -0.947110706367598 1.87295050823663e-23 465.323225582075 55.1110054776439 8.44338116405508 2.88845849473307e-16 -723.523230860338 185.368359997742 -3.90316465479412 0.000107019853638362 NACC1 other 2.36366354139463e-19 1 3.77723717356243e-12 8.44338116405508 -3.90316465479412 6.01322065270531e-05 12.8685943675276 6.36728879539025 2.02104769880143 0.043768662541554 80.180340657702 18.1445824206492 4.41896863751759 1.19945384467048e-05 HK3 other 0.336559959931916 0.144114379437158 1 2.02104769880143 4.41896863751759 8.85346827400894e-12 115.699121077769 15.9412338602726 7.25785231506477 1.4172200408894e-12 199.539610683612 115.076361178389 1.73397567180883 0.0835071989933442 LY6K other 8.04780266107412e-08 1 1.71752896755386e-08 7.25785231506477 1.73397567180883 8.51413888831248e-05 492.491912178647 200.56758682756 2.45549103904845 0.0143856464499073 -1866.04034528053 678.225625636218 -2.75135629611469 0.00613572585797056 IER2 other 0.466915376635057 1 1 2.45549103904845 -2.75135629611469 7.38193662907506e-25 37.6602005032 7.53883545444401 4.99549310112611 7.93729972514492e-07 -193.460720147481 23.8991291486382 -8.09488575689399 3.8217367006141e-15 ZNF394 other 9.52638921982137e-21 5.744070261023e-11 0.00768727478380285 4.99549310112611 -8.09488575689399 5.92492622652678e-20 91.0854830938919 13.5879841522632 6.70338455456035 5.13856462799961e-11 -213.792207505032 43.0757495752422 -4.96316859516495 9.31129829161765e-07 CPSF4 essential 7.01096520384914e-16 0.0118449025567668 5.96433196371914e-07 6.70338455456035 -4.96316859516495 2.65086474693072e-09 1878.17869541084 293.332877658459 6.40289186266291 3.39679305094734e-10 1922.7629355713 2101.69465626117 0.914863122406097 0.360685087758001 LY6E other 2.12175214344335e-05 1 3.85162364046919e-06 6.40289186266291 0.914863122406097 1.58827082154551e-17 497.873174780022 59.4391575594621 8.37618154803013 5.64809387470733e-16 -1028.15140640585 406.085109058624 -2.53186187690871 0.0116534613074272 VPS28 essential 1.76981017644817e-13 1 7.34986455915666e-12 8.37618154803013 -2.53186187690871 3.10323329886581e-21 133.478948488644 13.0971342186391 10.1914622130606 2.83609952914897e-22 85.3231384521065 89.4789124864515 0.953555827637329 0.340772990903048 TONSL essential 3.76639425483344e-17 1 3.97762958963143e-18 10.1914622130606 0.953555827637329 9.2735032012521e-14 35.7345680524002 40.1258499638666 0.890562270570699 0.373570425211524 -468.4357525933 72.0394992506356 -6.50248485158879 1.83642177786326e-10 MUM1 other 9.12976390163269e-10 2.61267726336606e-06 1 0.890562270570699 -6.50248485158879 3.04062459610158e-22 188.257726533739 17.9899176815976 10.4646241225613 2.74945382428079e-23 117.588628249625 122.909358580526 0.956710128566693 0.339180592454408 RECQL4 ts 3.76338106259493e-18 1 3.89240177903431e-19 10.4646241225613 0.956710128566693 7.30722535192215e-28 168.100180059644 15.366127053382 10.9396583456366 4.37220549551746e-25 -340.71134741326 104.664556036508 -3.25526959952342 0.00121073448248279 LRRC14 other 9.79095124904048e-24 1 6.26668213672518e-21 10.9396583456366 -3.25526959952342 6.10020037497205e-38 84.322299888192 6.50894016523214 12.9548432997747 1.18787223573516e-33 -47.9244879491861 24.1415450656317 -1.98514584791063 0.0476290733394031 ZNF333 other 8.85139074408444e-34 1 1.76814782289179e-29 12.9548432997747 -1.98514584791063 0.255461775738989 11.9945461532495 7.8780148919255 1.52253407968843 0.128458513279328 -3.21753437426477 22.8837848457243 -0.140603243561169 0.888235623329505 COL26A1 other 1 1 1 1.52253407968843 -0.140603243561169 2.61925573523652e-18 215.321048636958 24.8182765303495 8.67590657931658 5.9316675161399e-17 -402.645679912825 169.561556834678 -2.37462834990011 0.0179468654279354 PPP1R16A other 2.97992724997859e-14 1 7.852341457866e-13 8.67590657931658 -2.37462834990011 3.07709350785325e-11 113.747744581343 16.5592254204024 6.86914645422945 1.94583826478418e-11 -111.208639835908 113.134690832629 -0.982975593228336 0.326099649595294 FOXH1 other 2.72415088250248e-07 1 2.28791663173324e-07 6.86914645422945 -0.982975593228336 1.23303031177266e-08 63.7176944338657 37.4542121584721 1.70121571812191 0.0894749768394927 -552.676265763146 108.812008982961 -5.07918446620804 5.2196233826016e-07 ORAI2 other 9.48200309753179e-05 0.0067119137076874 1 1.70121571812191 -5.07918446620804 3.27474639780112e-18 34.4315424526547 7.93704490497218 4.33808084304588 1.7146279159076e-05 -151.191492708175 23.1561116000534 -6.52922629323597 1.52254648534398e-10 ALKBH4 other 3.71487231366559e-14 2.16841070442689e-06 0.151453083812118 4.33808084304588 -6.52922629323597 6.08002040863148e-07 20.8288951167767 5.18717877829932 4.01545734338575 6.76988178778222e-05 -33.3902172744516 15.0383300895793 -2.22034076094587 0.0268084418522455 SH2B2 other 0.00413562988195113 1 0.568196178448561 4.01545734338575 -2.22034076094587 2.92167019268777e-19 1868.08288101347 239.72530512335 7.79259778208334 3.44953040443209e-14 -1778.09359358323 643.019980553572 -2.76522292830229 0.00588516474052356 MRNIP other 3.40316144044272e-15 1 4.34295877918001e-10 7.79259778208334 -2.76522292830229 9.92998416795892e-18 3315.19595259173 447.307096824915 7.41145395663007 4.95769863869963e-13 -3205.43089498007 1199.89900952808 -2.67141723555615 0.00778501121264627 SQSTM1 other 1.11315122522819e-13 1 6.06772736390448e-09 7.41145395663007 -2.67141723555615 4.79941730341417e-06 310.364415898339 62.1180618200773 4.99636348599057 7.95598741664093e-07 323.926534996844 166.704956495048 1.94311280124695 0.0525336392285777 MGAT4B other 0.0300155558155522 1 0.00770378261553341 4.99636348599057 1.94311280124695 1.17481188327887e-13 130.501164691515 28.8570991616456 4.52232443602528 7.52980615892063e-06 -364.697522126168 77.572304386869 -4.70138827264105 3.28744757098497e-06 MAML1 other 1.15296038224989e-09 0.0407512000899297 0.0684609975969064 4.52232443602528 -4.70138827264105 0.0164783303001998 -32.134244301113 18.2838426822016 -1.75752137335956 0.0793914128301393 -183.315839866325 68.9921246985921 -2.65705456480986 0.00811425232776215 PGLYRP2 other 1 1 1 -1.75752137335956 -2.65705456480986 0.329482755431689 4.06510057945983 4.48705753373752 0.90596132295941 0.36536112440135 -11.4490794537297 13.3450587028671 -0.857926496139726 0.391314374911482 FBXL13 other 1 1 1 0.90596132295941 -0.857926496139726 4.99775832272475e-14 25.9524703633103 12.3119046241195 2.10791678100466 0.0354984026822334 -248.251229482417 36.6206401147784 -6.77899754631091 3.17948252907217e-11 NAPEPLD other 4.97226975527886e-10 4.58227022089881e-07 1 2.10791678100466 -6.77899754631091 0.636461977260975 -47.2764971430746 135.558793937574 -0.348752712899215 0.72741425380496 -342.920594146884 360.737670530642 -0.950609326834235 0.342238479528234 SCGB3A1 other 1 1 1 -0.348752712899215 -0.950609326834235 1.7287397891673e-24 317.670603750296 38.3971437296505 8.27328735665796 1.01966172440799e-15 -499.388591982403 113.720357183472 -4.39137375533132 1.35534496067686e-05 PSMC2 essential 2.21676303164922e-20 0.162397433188301 1.31964620372882e-11 8.27328735665796 -4.39137375533132 0.774780531628779 0.408884228558264 3.98192119785001 0.10268516332745 0.918250620158985 -5.44841654789181 9.00439986575288 -0.605083806708117 0.545375167764822 CELF5 other 1 1 1 0.10268516332745 -0.605083806708117 0.000575851025706151 141.961526287982 45.7968518053146 3.09980971817604 0.00203683795507657 -106.341098662797 109.902807318182 -0.967592195847435 0.333678835272041 MFSD12 other 1 1 1 3.09980971817604 -0.967592195847435 2.4708201902226e-07 28.9107179624051 6.05175883770824 4.77724224274498 2.29845003051923e-06 -0.87993594387462 12.3604960270447 -0.0711893715227388 0.943273643477907 USP41 other 0.00173575118363138 1 0.0216513992874911 4.77724224274498 -0.0711893715227388 9.02022176564816e-07 4.69141801540228 1.2990713127261 3.61136295555426 0.0003336023217954 -4.24190697355188 2.64316336984893 -1.6048599272902 0.109121424847978 TUBA3FP other 0.00605527487127961 1 1 3.61136295555426 -1.6048599272902 1.22487064126808e-14 140.57002812401 19.0818849757967 7.36667411538788 6.7763532994137e-13 9.74455014788202 41.1130315185491 0.237018526436941 0.812734348112659 YDJC other 1.24728577400328e-10 1 8.26240757797512e-09 7.36667411538788 0.237018526436941 2.94507387024098e-38 602.482149059351 42.2555013693728 14.2580759790969 2.33544570613487e-39 23.0994421870026 186.247807932044 0.124025310383416 0.901341557841086 DVL3 other 4.2797813482342e-34 1 3.52535529341059e-35 14.2580759790969 0.124025310383416 3.33522851191865e-41 1799.75830301268 120.590904011609 14.9244946603885 2.1327581800932e-42 -429.744722545111 531.523489270081 -0.808515016213603 0.419151538337579 AP2M1 essential 4.90878932384186e-37 1 3.23688708992745e-38 14.9244946603885 -0.808515016213603 3.05995620559814e-41 279.611486456454 18.8736345862967 14.8149252958127 6.8023858493481e-42 -208.588930296224 83.1885306171284 -2.507424145478 0.012454986104029 ABCF3 other 4.50486752588158e-37 1 1.03151379019515e-37 14.8149252958127 -2.507424145478 1.74726089441356e-47 420.320332943858 25.8423982933341 16.2647571704782 1.0936855847941e-48 -60.9573999239326 121.326111849636 -0.50242605647397 0.615573054163862 PCYT1A essential 2.62543421994581e-43 1 1.67410452464432e-44 16.2647571704782 -0.50242605647397 4.53234767712872e-12 70.1291833600458 9.79098282002436 7.16262960002532 2.57858635152738e-12 -12.7248002200847 52.1221997095031 -0.244133983043787 0.807218931194851 FBXO27 other 4.17383897586783e-08 1 3.10642297768503e-08 7.16262960002532 -0.244133983043787 8.30851567402551e-06 758.724021172885 157.234203133637 4.82543877891523 1.81445077614497e-06 69.8561501575813 853.60175528557 0.0818369335876203 0.934806321323977 DMKN other 0.0508398074093621 1 0.0171845573013265 4.82543877891523 0.0818369335876203 3.70787187240704e-11 40.6563160877224 6.50870438875636 6.24645300498749 8.46301630367438e-10 -60.6277189482005 29.8871070503475 -2.02855762674078 0.0429890827157777 U2AF1L4 other 3.26960141708852e-07 1 9.44895770305245e-06 6.24645300498749 -2.02855762674078 2.56353229690739e-12 146.836823713874 21.4536797889794 6.84436540296004 2.14167585304332e-11 -281.634535948484 91.9969083455479 -3.06134783237108 0.00231581241128062 BDH1 other 2.38305962320511e-08 1 2.5164691273259e-07 6.84436540296004 -3.06134783237108 9.18360350956315e-21 35.5877247400498 3.77027970728889 9.43901447716196 1.11101034396413e-19 -24.9755417832931 17.3889575425278 -1.43628746704401 0.151498547069504 THAP8 other 1.10497117427064e-16 1 1.52219527226526e-15 9.43901447716196 -1.43628746704401 0.586157132922079 -2.8554985558923 27.0342405806728 -0.105625255030605 0.915918837417038 -131.264556146776 127.796137856661 -1.0271402434243 0.304813449218618 COX7A1 other 1 1 1 -0.105625255030605 -1.0271402434243 4.424697321577e-09 21.7622232213045 3.76585536765985 5.77882608243339 1.27356496126557e-08 -18.0557401286583 16.7062564227606 -1.08077714550455 0.280279590214697 ZNF382 other 3.4990506419031e-05 1 0.000135787496170135 5.77882608243339 -1.08077714550455 2.66568136190018e-19 30.5405311414196 14.3372753177228 2.13014889263286 0.0336107252744143 -202.059814649335 29.471517420383 -6.85610488822632 1.94006844653166e-11 LRRC56 other 3.10978387679275e-15 2.80533897368479e-07 1 2.13014889263286 -6.85610488822632 0.0141139184834265 4.02947543373301 9.33608395588371 0.431602313429668 0.666212512122937 -205.56938343136 73.2977226177336 -2.80458077126702 0.00523004435363021 PLXDC1 other 1 1 1 0.431602313429668 -2.80458077126702 4.72537809406247e-206 467.225789644313 9.08056543019328 51.4533806552141 1.30180717748979e-203 -517.113198545541 181.379236086883 -2.85100549380325 0.00453540154525901 PGAP3 other 7.40892031368055e-202 1 2.04110347358624e-199 51.4533806552141 -2.85100549380325 3.20697413367285e-08 16.4525393689554 2.91539726406353 5.64332675061358 2.76224460727105e-08 159.626517005552 58.1796221828409 2.74368431791968 0.00628808608755037 IKZF3 other 0.000240440717974109 1 0.000290450020454551 5.64332675061358 2.74368431791968 3.77088566528626e-09 57.1473928798073 9.21960530813674 6.19846413917221 1.13707224868534e-09 2.84392628626169 29.6648929568184 0.0958684155847599 0.923660844608404 GRIN2C other 2.99408321823729e-05 1 1.26305985383968e-05 6.19846413917221 0.0958684155847599 2.32799916728647e-22 105.435343814398 14.8046754374324 7.12175989672923 3.44686792772555e-12 -279.783799177855 47.7339030835589 -5.86132247949826 8.02886386258274e-09 FDXR essential 2.88718456726867e-18 0.000110123896739185 4.14037775478393e-08 7.12175989672923 -5.86132247949826 5.69323783272956e-43 285.385754665316 18.873660506077 15.1208481562666 2.64552737555561e-43 40.4426844217521 69.2021638926957 0.584413581119547 0.559187066492271 SAP30BP essential 8.44193305837139e-39 1 4.02146616358208e-39 15.1208481562666 0.584413581119547 1.72288281991203e-39 444.954859420274 31.6977365369962 14.0374332060254 2.05761361816592e-38 -108.402631789447 111.605855319566 -0.971298786063267 0.331831969830295 ACOX1 other 2.51713179989147e-35 1 3.09979491576695e-34 14.0374332060254 -0.971298786063267 1.50843079212334e-31 292.175728383028 22.9516341484351 12.7300621164245 1.12151660773377e-32 182.69454877716 74.4305793904383 2.45456303408313 0.014417729532005 PRPSAP1 other 2.09385278254641e-27 1 1.66399419089459e-28 12.7300621164245 2.45456303408313 0.214336251060903 -11.9837397366382 12.4669857788369 -0.9612379406882 0.336861168666631 -65.5296009050718 39.7806903235129 -1.64727158760088 0.100081831902913 CYGB other 1 1 1 -0.9612379406882 -1.64727158760088 8.94268850066449e-07 24.3565560919515 5.03955783388676 4.83307403045844 1.75308172997074e-06 -31.3455094154254 21.2917503847759 -1.47219034832562 0.141549895065881 ZNF577 other 0.00600590959704627 1 0.0166192148001226 4.83307403045844 -1.47219034832562 1.1241712687211e-05 14.3702249658508 5.62852040323874 2.55310879882073 0.0109468963570246 -53.4109583128901 17.0513441122492 -3.13236059053674 0.00182685376277802 TMEM143 other 0.0680685703210625 1 1 2.55310879882073 -3.13236059053674 2.19709570430645e-07 150.800203737031 29.5720825199944 5.09941102846145 4.71175279424589e-07 -112.422955966978 106.487466841684 -1.05573885172908 0.291556168830922 ALDH16A1 other 0.00154983130981777 1 0.00462929712034658 5.09941102846145 -1.05573885172908 0.641028498553234 -1899.47163769887 2472.0078507301 -0.768392235137064 0.442589471006876 -5315.00615823986 7272.92593917507 -0.730793383940702 0.465221733390119 DCD other 1 1 1 -0.768392235137064 -0.730793383940702 0.434152202864287 -100.369292977476 91.1351640548158 -1.10132344653602 0.2712465610394 104.755182496905 287.391216998052 0.364503771517885 0.715624551025273 ITGA5 other 1 1 1 -1.10132344653602 0.364503771517885 1.05793306185296e-18 308.733461622646 71.164058518579 4.33833409799195 1.71381513636468e-05 -1564.79509959616 224.413107676787 -6.97283289641831 9.10640494724705e-12 ZNF385A other 1.2145071550072e-14 1.32252319048869e-07 0.151415567297819 4.33833409799195 -6.97283289641831 1.85454717761585e-09 39.5868705297847 9.68593567395584 4.08704660678559 5.03696166735045e-05 -63.233156334552 21.5516053672563 -2.93403462326863 0.00348889116640692 MPP3 other 1.49903048366689e-05 1 0.427537306324706 4.08704660678559 -2.93403462326863 0.127816357783124 -3.94742004889191 27.1549383182232 -0.145366562893014 0.88447621270904 -115.888734670177 60.5143531965982 -1.91506194065528 0.0560175027805334 CD300LG other 1 1 1 -0.145366562893014 -1.91506194065528 1.67926353068999e-07 32.5978175770767 13.1865381175362 2.47205273184827 0.013742811353757 -114.794773783128 30.7657205089976 -3.73125582251701 0.000210821355449617 NAGS other 0.00119546770749821 1 1 2.47205273184827 -3.73125582251701 3.58745996232814e-39 147.296465361255 13.478053452403 10.928615610661 3.05781702955283e-25 -142.046334255784 31.4372646158653 -4.51840629238773 7.66814832956006e-06 LSM12 essential 5.23374533904052e-35 0.0932446836874503 4.38552118378466e-21 10.928615610661 -4.51840629238773 2.68809558523705e-14 21.1869926109803 4.91140757293951 4.31383311124793 1.90999417560437e-05 -54.0133957836019 11.5081230347565 -4.69350176570692 3.41309474628479e-06 ASB16 other 2.70072963448767e-10 0.0422711784327371 0.168155887220209 4.31383311124793 -4.69350176570692 5.17122761889756e-07 455.542621018792 98.5485900860136 4.62251789316511 4.74017466378355e-06 -597.938781020905 344.926910786751 -1.7335231387341 0.0835693267666476 EMC10 other 0.00353505120027838 1 0.0436854497014292 4.62251789316511 -1.7335231387341 0.0126347370402928 47.3485830668029 20.0511898070166 2.36138521067882 0.0185583203360026 -84.0946767135497 70.1805571413711 -1.19826174283784 0.231336904395604 JOSD2 other 1 1 1 2.36138521067882 -1.19826174283784 0.355860860153328 0.187845822770852 2.08394087173735 0.0901397085293731 0.928209433624518 -10.180161445225 7.40163976815055 -1.37539271892568 0.169576856929451 SHANK1 other 1 1 1 0.0901397085293731 -1.37539271892568 4.90680669681728e-11 39.1494377535246 6.40637836825297 6.11100929466342 1.90381041466104e-09 84.3481186922505 15.0190461828603 5.61607692427953 3.13773141936437e-08 FAM171A2 other 4.29639994373321e-07 0.000422119007847088 2.09476259925154e-05 6.11100929466342 5.61607692427953 3.36339574193576e-27 65.880950405341 6.34377035432448 10.3851411267482 3.70633411808119e-23 -14.7905562257557 14.970107351463 -0.988006022836583 0.323592182976091 DBF4B other 4.47365267634875e-23 1 5.24038580955499e-19 10.3851411267482 -0.988006022836583 3.37361585349173e-09 84.4267672548369 39.66964753161 2.12824596406013 0.03377309056159 -464.255052961428 97.261807057235 -4.7732513615363 2.34258292651264e-06 PLCD3 other 2.68539821937942e-05 0.0292565181692163 1 2.12824596406013 -4.7732513615363 0.00951467423795041 -48.5760576660567 33.8493753882856 -1.43506511150772 0.15184961232895 -294.990923787109 98.1877227107943 -3.00435650856255 0.00278538895372075 FMNL3 other 1 1 1 -1.43506511150772 -3.00435650856255 0.20255366195794 55.2239259004158 121.409381686758 0.45485715463815 0.649394474235668 635.630050858516 355.231585616104 1.78933990274569 0.0741193546531581 AQP5 other 1 1 1 0.45485715463815 1.78933990274569 2.44427187746864e-08 267.933328952418 49.4787178263941 5.41512271786258 9.21818555802078e-08 580.494814425399 145.068641464592 4.0015182369174 7.16916719170939e-05 RACGAP1 essential 0.000184786953936629 0.816998293167202 0.000943942201141327 5.41512271786258 4.0015182369174 6.62694246348562e-16 320.157349926408 48.3319093538329 6.6241403289609 8.41971499751159e-11 -503.287523754109 142.080747342244 -3.54226405173525 0.000430840352446956 LARP4 other 7.04775330991696e-12 1 9.71887702162763e-07 6.6241403289609 -3.54226405173525 0.0137191771656086 -14.0965916832125 7.71707577784387 -1.82667529631944 0.0682974446369648 -62.2094273246326 22.8256870797901 -2.72541313245782 0.00662933278946669 GRASP other 1 1 1 -1.82667529631944 -2.72541313245782 9.11868467873384e-42 388.395324554903 29.4558977104941 13.1856556663874 1.22174592984747e-34 -425.184358502323 108.970676136589 -3.90182362426913 0.00010745851871416 RAVER1 other 1.34573548488754e-37 1 1.82382232407631e-30 13.1856556663874 -3.90182362426913 9.6185633570752e-10 9.13747232243165 1.82485584995672 5.00722965194669 7.49688371071006e-07 -14.7848242881539 5.74630271401093 -2.57292819817947 0.0103510740692662 SYCE2 other 7.87664153310888e-06 1 0.00727047782264662 5.00722965194669 -2.57292819817947 1.89936283576179e-18 109.720175514828 11.755308846533 9.33367016955815 2.61058417971597e-19 59.7267067654673 39.7926822290269 1.50094699376408 0.133951578205121 SPC24 essential 2.16793274073851e-14 1 3.5634474053123e-15 9.33367016955815 1.50094699376408 0.810468800867819 -2.08780042391786 8.88962476399888 -0.234858104739472 0.814407567340751 -19.6180379625987 30.2772400304473 -0.647946706597776 0.517293797399906 IP6K3 other 1 1 1 -0.234858104739472 -0.647946706597776 1.6073055275899e-23 215.631964649169 23.5750966629732 9.14659938543704 1.17622258428889e-18 -191.250870590792 80.4268251837599 -2.377948777088 0.0177543464295988 LEMD2 other 2.03147345632087e-19 1 1.59366397945301e-14 9.14659938543704 -2.377948777088 0.0554887070586978 20.5430006075743 14.5684482752956 1.4101021755632 0.159078909038519 -32.5373687134761 27.3030288284311 -1.19171279193737 0.233891611883658 ALOX15 other 1 1 1 1.4101021755632 -1.19171279193737 3.01460668904474e-50 53.9993979271523 3.23393160686417 16.6977550831737 8.02643367117752e-51 32.6602801013227 14.6285882650881 2.2326337654378 0.0259799910470146 ADCY10P1 other 4.56200430253141e-46 1 1.2310141321485e-46 16.6977550831737 2.2326337654378 5.06458621195238e-22 28.887350759681 3.47637060636904 8.30962921696455 7.80301538387726e-16 -46.4941082078122 12.1386556013473 -3.83025186105881 0.000143037777943404 ZNF653 other 6.24412834071609e-18 1 1.01259730636575e-11 8.30962921696455 -3.83025186105881 2.22204879774814e-54 48.8118337787716 6.4580339145678 7.55831177483655 1.73555970679142e-13 -138.625922859443 12.0861951110586 -11.4697737034382 1.95630805201495e-27 MED11 essential 3.38506913848951e-50 3.05497065402655e-23 2.15001136477322e-09 7.55831177483655 -11.4697737034382 3.1302285606875e-07 456.928680636886 84.0624708975291 5.43558469978685 8.24486836918813e-08 192.542332332955 157.090464946222 1.22567803462082 0.22084826759259 CXCL16 other 0.00218051721537491 1 0.000846665532831929 5.43558469978685 1.22567803462082 0.111234996242822 -1.94467928840244 4.6101789575646 -0.421822950107288 0.673320586962881 -17.359998862354 8.47800789634569 -2.04765070693515 0.041073029133691 SCIMP other 1 1 1 -0.421822950107288 -2.04765070693515 4.19367657329296e-25 610.362742141898 95.010338468317 6.42417185310244 2.88475874265445e-10 -980.40000722943 173.662363719961 -5.64543742368019 2.64915851046337e-08 RNASEK-C17orf49 other 5.42284317692513e-21 0.0003573184998913 3.27708593165545e-06 6.42417185310244 -5.64543742368019 0.0589288097292567 -35.8527759801464 15.6275309504583 -2.29420604533149 0.0221566993109342 -43.9759465200285 28.5148616434025 -1.54221146397192 0.123600503752655 BCL6B other 1 1 1 -2.29420604533149 -1.54221146397192 0.578492112810804 -9.16932026164798 12.0748809699944 -0.759371482371823 0.447957485192668 7.59028828110853 22.0160008464359 0.344762354164666 0.730405553061607 ASGR2 other 1 1 1 -0.759371482371823 0.344762354164666 2.47545065220785e-33 34.1111171061105 43.8188608427106 0.778457414229766 0.436637240676056 -899.24137313343 78.3252197287129 -11.4808662682089 1.78394044494556e-27 TNFSF13 other 3.48989032948263e-29 2.78597979287148e-23 1 0.778457414229766 -11.4808662682089 3.0978132023035e-35 1264.27561803684 116.04827857745 10.894393553568 3.86054801643162e-25 -529.597245864031 207.590310326881 -2.55116553865209 0.0110083868020213 SENP3 other 4.4277044100524e-31 1 5.53448163635637e-21 10.894393553568 -2.55116553865209 0.000360644145994709 53.8984259292938 14.157523067717 3.80705195898264 0.000156688103526881 71.1417109063953 25.4768597040834 2.79240501901389 0.00541654253787519 FGF11 other 1 1 1 3.80705195898264 2.79240501901389 2.27544235900955e-31 2266.29751378853 226.135949902226 10.0218364871592 8.24419588636072e-22 -1066.94416287864 404.518124626357 -2.6375682520138 0.00858873797533695 EIF4A1 essential 3.15490083076674e-27 1 1.15179660728346e-17 10.0218364871592 -2.6375682520138 1.56688808256815e-28 807.667931083376 238.682830468043 3.38385433715356 0.000766354532970828 -3768.77007574814 424.527244793518 -8.87756939506013 9.94032933818735e-18 RPL26 essential 2.11388871219269e-24 1.51838530640812e-13 1 3.38385433715356 -8.87756939506013 1.09262934886846e-24 150.937208846595 15.6507068762826 9.64411448247929 2.27432054754492e-20 -121.681563591962 69.1455102823431 -1.75978979828332 0.0790269178008001 POLR3K essential 1.40599544612393e-20 1 3.13924465177626e-16 9.64411448247929 -1.75978979828332 6.41674250015763e-19 221.387009272216 25.9068381206337 8.54550479071742 1.4035364405389e-16 -112.319558851033 114.457548519289 -0.981320675692302 0.326887488449473 SNRNP25 essential 7.39914577693176e-15 1 1.84424688286812e-12 8.54550479071742 -0.981320675692302 2.33666814192393e-15 227.95060237201 32.5457451427014 7.00400624943532 7.52947901885309e-12 -301.105518879883 143.231354982453 -2.10223186757377 0.0360014932599539 WDR90 other 2.44018254061116e-11 1 8.96233887614083e-08 7.00400624943532 -2.10223186757377 1.6359664852945e-21 732.150898039128 90.3432845100295 8.10409873860461 3.64375081338963e-15 -1230.02688123524 395.033864280532 -3.11372515740002 0.00194647010513912 JMJD8 other 1.99522472546517e-17 1 4.67274604309086e-11 8.10409873860461 -3.11372515740002 5.83640141089852e-09 60.5762724896148 12.945367811973 4.6793782432036 3.65004563761811e-06 -131.724261448269 56.6248148676526 -2.32626387840992 0.0203771373785898 CCDC78 other 4.58040782727316e-05 1 0.0339052739278346 4.6793782432036 -2.32626387840992 8.71009744080287e-14 242.551452069183 34.8401700117443 6.96183319390866 9.72891335042011e-12 -219.602466752724 159.474719720975 -1.37703622954755 0.169068460353966 SPSB3 other 8.58770079409533e-10 1 1.15482201469487e-07 6.96183319390866 -1.37703622954755 9.24776996809795e-07 98.8893562642393 18.9417737872881 5.22070199838434 2.54243066660703e-07 240.571281128256 86.0623024540715 2.79531541997312 0.00536837113013663 CCNF other 0.00619970498661287 1 0.00253785429140714 5.22070199838434 2.79531541997312 3.76930721144867e-07 109.679693880183 24.554512309074 4.46678364040044 9.6624156973258e-06 -171.668909873956 112.675894545357 -1.52356376283174 0.128198809343218 TBC1D24 other 0.00261137603609164 1 0.0871839768369707 4.46678364040044 -1.52356376283174 3.30553839330806e-11 116.845694735101 22.2842021467424 5.24343182518572 2.26007125914081e-07 -280.639872418998 102.900441515516 -2.72729512415825 0.00659177144016169 AMDHD2 other 2.92110427816633e-07 1 0.00226300935177769 5.24343182518572 -2.72729512415825 3.27404802902417e-14 187.360313022275 27.7627541109642 6.74862127415095 3.84499069382592e-11 -255.609982513981 127.027443195686 -2.01224220596343 0.0446886346485126 BICDL2 other 3.28223314909673e-10 1 4.48056765551534e-07 6.74862127415095 -2.01224220596343 1.25837977096143e-06 301.20706486158 58.0848778575619 5.185636536935 3.04506307634126e-07 214.446927479528 264.28853492499 0.811412146729679 0.417485206880694 PAQR4 other 0.00832292380513892 1 0.00302770621680611 5.185636536935 0.811412146729679 1.66982517128051e-23 196.161249265736 22.0130581950363 8.9111311807629 7.63578341724951e-18 -269.730008950322 100.200412374218 -2.69190517842345 0.00732370705288309 FLYWCH2 other 2.10949013887867e-19 1 1.02479849242906e-13 8.9111311807629 -2.69190517842345 3.64709172875685e-05 477.182623761207 139.904106641174 3.41078353750605 0.000695961534190377 -1091.78933239738 636.82424559497 -1.71442802303695 0.087020761493196 ZG16B other 0.209780716238094 1 1 3.41078353750605 -1.71442802303695 4.28965325736905e-11 91.3449339269175 16.3616826664438 5.58285695848733 3.7419025647322e-08 -174.399089294048 75.6400346778771 -2.30564528475891 0.0215064116026011 ZNF75A other 3.77103417855314e-07 1 0.000390804303860631 5.58285695848733 -2.30564528475891 4.3608245346507e-15 212.560104221043 38.1868982250226 5.56630975808764 4.09385355703058e-08 -841.012269672394 189.970997847188 -4.42705612542447 1.15529589979796e-05 ADCY9 other 4.51345339336348e-11 0.138924331950705 0.000426784233320438 5.56630975808764 -4.42705612542447 7.30388530122813e-37 290.458197706048 21.6843854152073 13.394808851827 4.01285078397862e-35 -288.812814289739 176.509438716529 -1.63624572368375 0.102425071773172 SHANK2 other 1.05300114387806e-32 1 5.99760678173445e-31 13.394808851827 -1.63624572368375 2.55160327664332e-31 130.183554398579 11.5537073992123 11.2676866308259 2.34789666675864e-26 -43.2381009049219 34.6479572460202 -1.24792641014611 0.212651595484646 CLPB other 3.53575666044464e-27 1 3.3901279971328e-22 11.2676866308259 -1.24792641014611 1.79105378546272e-77 191.788155569817 8.98684881175917 21.3409794230504 4.75547978737204e-73 -24.7214097086729 38.35683526708 -0.64451119432917 0.519528207123839 NEU3 other 2.78240205571634e-73 1 7.39096668553362e-69 21.3409794230504 -0.64451119432917 2.0571927426218e-13 122.590123871112 31.3195729657012 3.9141697112334 0.000102831434438519 -396.984211542481 82.5524338645179 -4.80887349964747 1.99257533806289e-06 CYB561A3 other 2.00000278437692e-09 0.0249530209585616 0.848770659855535 3.9141697112334 -4.80887349964747 0.00010679476002523 7.31787376855355 2.30577088631102 3.17372112381093 0.00159438659548641 -9.29162713795711 6.07680534597039 -1.52903155670742 0.126867021671438 PPP1R32 other 0.577759651736496 1 1 3.17372112381093 -1.52903155670742 0.017024914901018 -18.2803942932615 35.3247448066237 -0.517495438207206 0.605029574489327 -243.887959014108 87.2102073392001 -2.79655290883001 0.00535557862632352 ASRGL1 other 1 1 1 -0.517495438207206 -2.79655290883001 0.240560017892799 0.104921342093341 3.5295179790167 0.0297268189925956 0.976296372375785 13.8015974518582 8.85798431792772 1.55809684872946 0.119821015041615 GNG3 other 1 1 1 0.0297268189925956 1.55809684872946 2.80405424814294e-06 125.090057901409 60.241472946422 2.0764774130384 0.0383432530840328 -517.229976859959 150.270283428978 -3.44199774604417 0.000624215064889528 UBXN1 other 0.0179599674593555 1 1 2.0764774130384 -3.44199774604417 2.30640851001022e-12 228.751885788483 42.7780498899127 5.34741266554144 1.34160761181451e-07 -284.817577888525 106.708374929898 -2.66912112639363 0.00784405444302703 LBHD1 other 2.14818888622352e-08 1 0.00135945099305164 5.34741266554144 -2.66912112639363 3.59907563088159e-27 53.957092016556 8.62519807144912 6.25575106444954 8.29100589861343e-10 -141.473239870531 21.6465448568708 -6.53560375597895 1.51849736188886e-10 TTC9C other 4.78569086638324e-23 2.1627957925383e-06 9.25856628698162e-06 6.25575106444954 -6.53560375597895 4.97637261520075e-13 34.3279978956693 8.69386056264195 3.94853329522892 8.95052086119239e-05 -100.139095186087 22.2517426938494 -4.50028101456371 8.3870710555437e-06 TAF6L other 4.75392875930128e-09 0.101760333116912 0.742535210644521 3.94853329522892 -4.50028101456371 5.21044094552576e-10 21.5011735627567 37.7902627179507 0.568960679718785 0.569629425229568 -566.675191540516 96.7233366895949 -5.85872252690261 8.30068100822255e-09 NXF1 essential 4.33508686667743e-06 0.000113794035941723 1 0.568960679718785 -5.85872252690261 4.34110692826426e-20 120.147646550891 26.004224401664 4.62031263440422 4.83716526243358e-06 -412.683720134268 67.3579326114376 -6.12672782751342 1.77231268435657e-09 STX5 other 5.14942103830706e-16 2.46900880057714e-05 0.0445551292322757 4.62031263440422 -6.12672782751342 6.78296300551706e-05 -3.04128452826072 11.6902664298 -0.260155279310665 0.794847174982736 -123.577370138329 29.2028659721386 -4.23168637818733 2.74275702145505e-05 SLC25A45 other 0.377268402366859 0.321752826186892 1 -0.260155279310665 -4.23168637818733 1.96354532876293e-14 136.861526127204 417.044415955244 0.328170144212868 0.742915118500297 -5336.66968227251 762.449174926726 -6.9993776080686 7.96542986993907e-12 RPL29 essential 1.98357349111631e-10 1.15817350308914e-07 1 0.328170144212868 -6.9993776080686 0.628429099876674 -28.8020968871207 40.0332612845766 -0.719454172928378 0.472175865332379 -66.5056760157512 73.1780768790965 -0.908819674581374 0.363855299781245 ITIH3 other 1 1 1 -0.719454172928378 -0.908819674581374 5.01358878527644e-14 109.506308203154 22.7292768015139 4.81785272621873 1.90381443451695e-06 -225.778433478492 54.8585047379074 -4.11565051867843 4.48514408976858e-05 ZFPL1 other 4.987518123593e-10 0.519245131272509 0.0180081807360958 4.81785272621873 -4.11565051867843 1.52841537093483e-11 113.55867397519 23.6966584216017 4.79218090394005 2.14228580934188e-06 -168.979813813842 56.2523207551857 -3.00396164185394 0.00279012392028906 RPS6KA4 other 1.37175279541401e-07 1 0.0202103243253313 4.79218090394005 -3.00396164185394 0.00411794292566939 263.552829980652 101.964044727948 2.58476240996364 0.0100302503201557 -527.050174918645 383.41383233681 -1.37462483214653 0.169870997937135 LRP5 other 1 1 1 2.58476240996364 -1.37462483214653 2.91127971239699e-73 87.5586669219045 4.09256370646646 21.394576407829 2.15103299027261e-72 -36.0306029812581 37.4299035190397 -0.962615438293348 0.336210546285241 TPCN2 other 4.51423032204278e-69 1 3.34205995698655e-68 21.394576407829 -0.962615438293348 0.0391405991858176 229.540173499316 113.46588705621 2.02298840166475 0.0435647486992641 -165.091626712512 235.087430202779 -0.702256290649436 0.482820815302101 PDZK1IP1 other 1 1 1 2.02298840166475 -0.702256290649436 0.0318522591443764 -12.3921202142019 4.99157609311581 -2.48260669236169 0.0133440909281622 -17.8644178422561 10.302194710144 -1.73404001233504 0.0834795880274198 TAL1 og 1 1 1 -2.48260669236169 -1.73404001233504 1.59845742533695e-14 796.898880989581 125.700834351347 6.33964671039626 4.85369334589835e-10 -650.761548707504 259.435987062512 -2.50837039254196 0.0124198988585176 CMPK1 essential 1.62067598354913e-10 1 5.46865629282367e-06 6.33964671039626 -2.50837039254196 1.98157999002934e-05 -0.819032789624529 4.91484823766518 -0.16664457375262 0.86771233041914 -45.2279615208659 10.1171847605332 -4.47040976233811 9.52615340617055e-06 BEND5 other 0.117329351209637 0.115161668527196 1 -0.16664457375262 -4.47040976233811 0.785192774952706 -4.30477944516479 10.7671481398085 -0.399806837360126 0.689457770020173 -14.6031021474146 21.7255936652966 -0.672161247807046 0.501770136359808 ELAVL4 other 1 1 1 -0.399806837360126 -0.672161247807046 2.21099976330032e-23 287.841727414887 29.0510313521548 9.90814143311085 2.21379369059012e-21 -28.4995360588267 60.3776319863452 -0.472021427824001 0.637101469192679 COA7 other 2.78630190171106e-19 1 3.08137943793238e-17 9.90814143311085 -0.472021427824001 4.18061923765902e-07 155.509973332892 39.2847915801499 3.95852865900069 8.54601436227727e-05 -183.304636609066 81.3419443707591 -2.2535069456117 0.0246260337443441 ZYG11B other 0.00288546339783225 1 0.710601094223355 3.95852865900069 -2.2535069456117 0.00180642708092737 -7.59002244143372 2.528461019931 -3.00183486381801 0.00280770885557838 -14.8563157406845 5.28933997241944 -2.8087277085895 0.00515386721403456 SLC1A7 other 1 1 1 -3.00183486381801 -2.8087277085895 4.08280724273938e-15 56.5987668144684 18.87776971171 2.99817021177877 0.00284065854675415 -254.190077285599 39.5517249147163 -6.42677602136692 2.85869780198552e-10 C1orf123 other 4.23060486492654e-11 4.05277587387487e-06 1 2.99817021177877 -6.42677602136692 9.33341098454387e-20 239.731687592996 27.9743233367512 8.56970460758381 1.08435104119134e-16 -93.2690418012399 58.6103527157758 -1.59134073554441 0.112115957673956 MAGOH essential 1.10040915507772e-15 1 1.42830719145723e-12 8.56970460758381 -1.59134073554441 0.00323466501327823 29.8012098248898 10.6373509465869 2.80156309353052 0.00526732617941544 -21.9764165936321 24.0303302687006 -0.91452827938267 0.360845988340116 ACOT11 other 1 1 1 2.80156309353052 -0.91452827938267 0.000133487880389638 12.2016979247292 3.46155388708748 3.52491924804199 0.000459375346793149 -8.69246161950593 7.81929488076198 -1.11166821971278 0.266772784371092 FAM151A other 0.714694111606121 1 1 3.52491924804199 -1.11166821971278 1.00894181996956e-31 67.750255569343 6.13794939108231 11.0379299750786 1.07276677859243e-25 -34.5119800616126 13.8649975755392 -2.48914432718684 0.0131034246839621 PARS2 essential 1.40283270648568e-27 1 1.54253135093805e-21 11.0379299750786 -2.48914432718684 7.7236754154521e-22 687.752196860946 73.7587399658659 9.32434850675628 2.81607325575311e-19 -190.147088351156 167.122391133002 -1.13777146833562 0.255718625569248 USP24 other 9.49085235050754e-18 1 3.84196874282396e-15 9.32434850675628 -1.13777146833562 0.0257225931691643 -148.011335761668 82.0324967180772 -1.80430124259587 0.0717401234529657 -445.182120206241 176.603719770673 -2.52079696160607 0.0119953367382237 PLPP3 other 1 1 1 -1.80430124259587 -2.52079696160607 1.9900076803559e-12 71.3820607548236 16.8012522482525 4.24861550199319 2.53125970227981e-05 -91.1550345657575 27.6030885964251 -3.30234909210714 0.00102186660002066 NOL9 essential 1.8580701711483e-08 1 0.220811113398277 4.24861550199319 -3.30234909210714 0.0786815727220998 -34.4040716496916 46.3621320152003 -0.742072682041712 0.458365938725689 -221.254199494293 97.9006221733168 -2.25998767507932 0.0242195716621975 PRKAA2 other 1 1 1 -0.742072682041712 -2.25998767507932 1.67659048198584e-07 175.57538011491 66.4570013654446 2.64193954748917 0.00848096325786106 -334.675955402779 109.164557326328 -3.06579318049469 0.00227893667919486 KLHL21 other 0.00119373242317392 1 1 2.64193954748917 -3.06579318049469 0.235445254955472 11.4912211466339 13.5095269449202 0.850601297401814 0.395364410406086 -32.7095360322808 29.1059731471429 -1.12380836287179 0.261589091003361 ZSWIM5 other 1 1 1 0.850601297401814 -1.12380836287179 8.63693662734426e-08 38.0880240232518 14.37109481148 2.65032167158387 0.00827648416382638 -74.3839714332835 23.4494770006176 -3.17209511458717 0.00159913184191264 GMEB1 other 0.000627387076610287 1 1 2.65032167158387 -3.17209511458717 1.42405095417431e-06 -0.484806126359949 5.78834450383964 -0.0837555757157091 0.933281808564608 -43.4944067690522 9.43121868826761 -4.61174830175012 4.99075910624714e-06 SLC45A1 other 0.0093773755332378 0.0613414201748836 1 -0.0837555757157091 -4.61174830175012 1.66224864002087e-19 361.583221393353 128.52368669365 2.81335861657334 0.00507996613359432 -1524.58408031741 226.042148533121 -6.74468938740433 3.92931660427122e-11 SELENON other 1.94865408069647e-15 5.65428659354629e-07 1 2.81335861657334 -6.74468938740433 1.52311868230689e-10 481.285488210158 88.5052617484072 5.43793079306745 8.2032967556572e-08 -368.200155855117 177.658497985462 -2.07251642916202 0.0386947478359969 AK4 other 1.30318034458178e-06 1 0.000842478576805994 5.43793079306745 -2.07251642916202 9.272259741895e-09 -168.294340679129 172.02247255212 -0.978327646279699 0.328352008995222 -2126.51134600957 350.210623123739 -6.07209263683077 2.38722926729125e-09 JAK1 og 7.18507407399443e-05 3.31586145226755e-05 1 -0.978327646279699 -6.07209263683077 1.99452477701193e-05 117.595873465761 30.1822273112563 3.89619600478937 0.000110056966374207 -61.9720534191631 58.3404867108763 -1.06224779587946 0.288600677359445 RAVER2 other 0.117996085808026 1 0.906099004158844 3.89619600478937 -1.06224779587946 2.63813236277821e-24 101.51926482966 19.463436811871 5.21589613442487 2.60765955410472e-07 -183.389194044679 31.9929865218448 -5.73216864013182 1.64756749226037e-08 LZIC other 3.37496273170217e-20 0.000223723189774035 0.00260140117117487 5.21589613442487 -5.73216864013182 0.691797732314937 5.51964538517764 32.4430252147604 0.170133498606856 0.864968635037123 -34.2965369171972 53.3281597929634 -0.643122452571908 0.520416632513859 RBP7 other 1 1 1 0.170133498606856 -0.643122452571908 0.00714024548347833 45.3925496290136 89.1196375804417 0.509343965722943 0.610717687087471 -334.623429855472 141.284038107147 -2.36844469013336 0.0182115590576171 FBLIM1 other 1 1 1 0.509343965722943 -2.36844469013336 0.646373895519108 -3.19040250388494 7.85556969131409 -0.406132544074119 0.684804921161697 -11.5670231346714 12.4536705686126 -0.928804328887908 0.353402432780957 SLC25A34 other 1 1 1 -0.406132544074119 -0.928804328887908 4.71410528325997e-05 -188.138595905869 124.540400662846 -1.5106631655634 0.131452788476891 -918.469924457613 208.006381583888 -4.4155853174495 1.21481147761336e-05 AKR7A3 other 0.267666897983501 0.145898858461365 1 -1.5106631655634 -4.4155853174495 0.241922012263687 19.4987960528136 11.6146626648145 1.67880864175963 0.0937625485545177 13.4797593899906 18.6739909962758 0.721846732853138 0.470698294233765 DRAXIN other 1 1 1 1.67880864175963 0.721846732853138 0.154695007836856 -41.4550956612874 43.5603522189199 -0.951670350435823 0.341686819347347 -133.987143251811 69.2978649861128 -1.93349597824784 0.053693607138223 PDPN other 1 1 1 -0.951670350435823 -1.93349597824784 0.0242472693673854 176.169372946055 76.8626963522779 2.29200094853079 0.02228524935212 -6.33613072931975 122.230636983377 -0.0518375006929029 0.958677133393297 DHRS3 other 1 1 1 2.29200094853079 -0.0518375006929029 0.482610152521658 -2.90513082566106 7.01438170970485 -0.414167769290574 0.678915701781936 -14.0066568443567 11.658346830264 -1.20142735915153 0.230112128799408 MATN1 other 1 1 1 -0.414167769290574 -1.20142735915153 0.754935142545466 -212.807518962544 284.102370578796 -0.749052246656709 0.45415187196156 -136.471903671959 472.367497557182 -0.288910444469009 0.772760785874107 LAPTM5 other 1 1 1 -0.749052246656709 -0.288910444469009 2.45791945258624e-09 343.399815372274 128.017506831445 2.68244417401764 0.00753251645624158 -886.604974236344 218.552104214526 -4.05672129043458 5.7107586089596e-05 SDC3 other 1.97198877680994e-05 0.655766411066831 1 2.68244417401764 -4.05672129043458 1.22437214340676e-20 162.568609470783 47.0148158294475 3.45781657553488 0.000588009287199828 -594.686756116819 84.6184209766924 -7.02786401888332 6.42774124363363e-12 PEF1 other 1.46777732551603e-16 9.35879125073057e-08 1 3.45781657553488 -7.02786401888332 4.64042891643989e-19 109.870980971455 29.3411483021432 3.7446039889117 0.000200082117593231 -350.253473526239 54.3559379384413 -6.44370213835523 2.58478570382288e-10 SYNC other 5.37361668523739e-15 3.66755243515429e-06 1 3.7446039889117 -6.44370213835523 1.31386707678478e-23 1164.43676625292 156.154290385335 7.45696300357482 3.55064840932401e-13 -1152.42803814525 289.54909965539 -3.98007812670398 7.83082763743518e-05 RBBP4 essential 1.66243601225578e-19 0.889347094783514 4.3637468950592e-09 7.45696300357482 -3.98007812670398 5.22975320473977e-20 408.775905936317 208.561683067314 1.95997606043668 0.0505124559985448 -3068.21842457349 386.370900838796 -7.94112190621112 1.169307903319e-14 KIAA1522 other 6.19516564633474e-16 1.75045393126854e-10 1 1.95997606043668 -7.94112190621112 5.49109181757484e-07 6.87821418690571 3.00000967146177 2.29273067094956 0.0222478070226991 -19.6458178500843 5.55873525965718 -3.53422441120103 0.000444119774364286 TSSK3 other 0.00374657194713131 1 1 2.29273067094956 -3.53422441120103 1.53295762036931e-12 79.3622350007644 32.32022005219 2.45549797843616 0.0143784156386433 -264.094427862984 54.3787787450725 -4.85657151480097 1.56060839064005e-06 TMCO4 other 1.43837413519252e-08 0.0196386959878144 1 2.45549797843616 -4.85657151480097 3.64906043545596e-12 -79.9538915757033 47.0106243099424 -1.70076217343052 0.0895560194712741 -542.816475144574 76.9169374008884 -7.05717743694648 5.16827547562742e-12 UBXN10 other 3.37173184236131e-08 7.53327833327453e-08 1 -1.70076217343052 -7.05717743694648 0.0150425127632071 222.891618899781 154.180070618088 1.44565778187958 0.14884693207374 -351.359069655299 252.021055432857 -1.39416553530349 0.163834688420361 CAMK2N1 other 1 1 1 1.44565778187958 -1.39416553530349 0.381537711104993 140.978606835378 101.812405078953 1.38468987866509 0.166711849811371 136.159337401446 168.258920954974 0.809225071863396 0.41873754221053 ALPL other 1 1 1 1.38468987866509 0.809225071863396 0.351834564822318 -27.3147990527305 31.5456835254405 -0.865880716475904 0.386935888171515 -73.862388322418 51.2616055633052 -1.44089104332095 0.15018867761315 WNT4 other 1 1 1 -0.865880716475904 -1.44089104332095 0.00415390380768263 0.315777679660311 10.0486115573194 0.0314250061174172 0.974942610432242 -58.2786125992106 19.6353463708243 -2.96804606848217 0.00313456588375341 SCNN1D other 1 1 1 0.0314250061174172 -2.96804606848217 0.000977990397056815 -20.7729104583728 185.024245505417 -0.112271288563447 0.910651137586061 -1231.44612153379 361.918769021341 -3.40254838085276 0.000718448098401572 MXRA8 other 1 1 1 -0.112271288563447 -3.40254838085276 6.46124408040344e-09 138.133289113549 47.3198328762412 2.91914152517864 0.00365611445109276 -367.290885457645 96.3222439362365 -3.81314710339165 0.000153001495070368 FAAP20 other 5.06109248818001e-05 1 1 2.91914152517864 -3.81314710339165 2.37270028267104e-07 -76.5150902345288 40.9363532618292 -1.8691232642326 0.062148748590009 -403.351153067068 72.8236432573447 -5.53873900048783 4.77194695967488e-08 MEGF6 other 0.00166872010880254 0.000638391064265306 1 -1.8691232642326 -5.53873900048783 1.00533047762086e-06 -1.80295696262689 1.07872640018601 -1.67137557986529 0.0952247334921611 -10.035226508676 1.91278101979167 -5.24640636060318 2.22850639735298e-07 CCDC27 other 0.00670555428573115 0.0029035209851112 1 -1.67137557986529 -5.24640636060318 0.220594391765723 -41.2517582605304 40.0442823374011 -1.03015351637359 0.303400835978554 -129.433356923227 77.3960695248967 -1.67235051751034 0.0950366235640419 DIRAS3 other 1 1 1 -1.03015351637359 -1.67235051751034 9.57758632279876e-06 86.045223605299 95.8994392495543 0.897244282955481 0.369987681330081 -942.776115351855 222.377034574258 -4.23953902055041 2.6339030155705e-05 NFIA other 0.0583658110511356 0.309351909178755 1 0.897244282955481 -4.23953902055041 2.79341600467395e-09 42.6918619711781 17.3409310041609 2.4619129134955 0.0141329364617776 -166.720370294628 35.6263382742552 -4.6796942478679 3.64150155244058e-06 OMA1 other 2.23277741253589e-05 0.0450126006897181 1 2.4619129134955 -4.6796942478679 0.000740495781304966 -10.0789480843879 41.6595007857591 -0.241936362517174 0.808921323145004 -312.887578413666 85.3751378077391 -3.66485591060801 0.000271911655344468 MYSM1 other 1 1 1 -0.241936362517174 -3.66485591060801 8.22660427290087e-13 66.6111489590445 15.1576041730635 4.39456976171861 1.33623770774245e-05 -158.691734128996 35.1805032984501 -4.51078635182536 7.9265716537932e-06 TM2D1 other 7.79388488814628e-09 0.0962919924502798 0.119232490661859 4.39456976171861 -4.51078635182536 1.24199972702132e-14 751.640487811504 96.6705308626324 7.77528044073303 3.80303511280449e-14 -2.3918228847657 215.461984243186 -0.0111009043807288 0.991147018922636 USP1 other 1.26447992208041e-10 1 4.78421817190805e-10 7.77528044073303 -0.0111009043807288 2.23744640112023e-07 293.364390405859 68.3916520368529 4.28947659061927 2.12413971136709e-05 -232.440086352527 138.506560059249 -1.67818828402855 0.0938921639543574 FUBP1 other 0.00157739971278976 1 0.186372018275349 4.28947659061927 -1.67818828402855 0.470998379997389 -25.1342302039589 50.5944307978815 -0.49677859415727 0.619548118657167 -125.297773263711 102.055352929942 -1.22774327525696 0.220080246910557 NEXN other 1 1 1 -0.49677859415727 -1.22774327525696 9.61987847388755e-05 58.4129197353553 25.1367020382778 2.32381000683403 0.0205073119865865 -125.768250191425 50.6680007830382 -2.48220273639704 0.0133613076856249 DNAJB4 other 0.523898581687916 1 1 2.32381000683403 -2.48220273639704 0.313251047851873 -60.7591814219825 44.0589801299522 -1.37904193975378 0.168450623979775 -100.061062382612 87.7845028274365 -1.13984882478982 0.254852756076112 ADGRL4 other 1 1 1 -1.37904193975378 -1.13984882478982 0.413891873196462 2.22919736003345 3.31815142897404 0.671819055805633 0.501985676183169 -5.56654321914917 6.61525565279754 -0.84147061146384 0.400456130787499 LRRIQ3 other 1 1 1 0.671819055805633 -0.84147061146384 7.69470378509786e-12 51.5268978659886 19.1077915111326 2.69664329527397 0.00722170437555434 -206.398781287157 38.4615646408669 -5.36636466078269 1.19173016468509e-07 TYW3 other 7.01603091125223e-08 0.00157243107573461 1 2.69664329527397 -5.36636466078269 1.6714464131964e-08 45.4536301708341 23.1858893947225 1.96040054349522 0.0504636749113034 -200.893046864223 44.5384608983548 -4.51055206695846 7.94089946193624e-06 SNX7 other 0.000127598219183413 0.0964501648646776 1 1.96040054349522 -4.51055206695846 0.672284716430047 -54.8141052464278 86.0913577296293 -0.636696954165504 0.524597667090159 -152.362731524882 182.335889244169 -0.835615698897602 0.403748385320314 NTNG1 other 1 1 1 -0.636696954165504 -0.835615698897602 2.90563140359551e-06 546.922955700818 111.189671204945 4.91882878844681 1.15804425556282e-06 173.162283468628 261.222306945274 0.662892405681516 0.507682837669465 FAM102B other 0.0185960409830112 1 0.0111033283223364 4.91882878844681 0.662892405681516 2.70779699332963e-21 238.692298327724 24.4126398401111 9.77740628998023 6.75444489194233e-21 69.4461364757696 57.2451958670882 1.21313475172676 0.225608700128408 HENMT1 other 3.28943178749683e-17 1 9.36638873165643e-17 9.77740628998023 1.21313475172676 4.15414076695506e-25 85.5940018005354 9.98019581485276 8.57638501172015 1.03862038148393e-16 -54.3910250955137 18.9117086441967 -2.87605028814805 0.00418588889779299 C1orf52 other 5.37213483982628e-21 1 1.36848621464322e-12 8.57638501172015 -2.87605028814805 0.00315903985104808 -3.70398690529626 1.9159040821416 -1.93328410321875 0.0537226308236296 -12.2219421299647 3.63297147117965 -3.36417233851721 0.000822140996598671 WDR63 other 1 1 1 -1.93328410321875 -3.36417233851721 0.0618555043316094 265.511144138619 150.470875599622 1.76453511738112 0.0782189631889523 -233.909880873208 312.44799131494 -0.748636212666292 0.454409221380363 GBP2 other 1 1 1 1.76453511738112 -0.748636212666292 3.7142945229271e-08 26.8964302895329 6.1279234580073 4.38915898245882 1.37011741623514e-05 -25.5713077940063 13.8052967149959 -1.85228237551965 0.0645328306574721 ATXN7L2 other 0.000277494943807884 1 0.12218707117985 4.38915898245882 -1.85228237551965 0.0238376924574383 354.179347930934 133.229518019198 2.65841499088736 0.00808858765597176 118.882790976278 276.646860218447 0.429727598868844 0.667568787025632 GBP4 other 1 1 1 2.65841499088736 0.429727598868844 1.02612102903467e-08 114.109136109791 24.9377086238819 4.57576667651467 5.89660904318466e-06 -97.557645239565 49.0028223394479 -1.99085768088566 0.0470019232788234 ZNF326 other 7.92473270723478e-05 1 0.0540424218807874 4.57576667651467 -1.99085768088566 0.0850114607118081 121.370008223267 61.4526684632147 1.97501607755111 0.0487897636674469 -354.245040810634 410.706013776736 -0.862527036195787 0.388791380194485 BRINP3 other 1 1 1 1.97501607755111 -0.862527036195787 0.266891935378449 3.9893471619458 2.6867109971931 1.48484417047967 0.13817077314112 -0.0804823385936301 5.15027883646486 -0.0156267924803996 0.987537924195233 GFI1 other 1 1 1 1.48484417047967 -0.0156267924803996 0.582015656530711 -1.53732114587251 1.5360852729372 -1.00080456010945 0.317375435173398 2.05149087382033 10.7055248536728 0.191629172960773 0.848105668266007 KCNT2 other 1 1 1 -1.00080456010945 0.191629172960773 0.318544417633182 120.847915557778 224.781407070404 0.537624161770315 0.591058850905948 -467.954118622936 433.517935902987 -1.07943427449713 0.280877862192516 AGL other 1 1 1 0.537624161770315 -1.07943427449713 0.970630643819367 -20.6344378391195 160.992796724033 -0.12816994461243 0.898062648177609 -74.5298648226916 308.072417638959 -0.241923199077289 0.808932376025672 VCAM1 other 1 1 1 -0.12816994461243 -0.241923199077289 1.49080863202553e-09 37.5352191226071 12.038457186465 3.11794265172187 0.00191914087912027 -91.0422171334894 23.0365375690361 -3.95207903360708 8.78705160013499e-05 EXTL2 other 1.21008936661512e-05 0.99469424113528 1 3.11794265172187 -3.95207903360708 1.57262429331754e-09 106.66951324888 36.882230361802 2.8921654737929 0.00398165579887691 -292.336507800428 70.5770575248425 -4.14208976759237 3.99910247188757e-05 SLC30A7 other 1.27445472730454e-05 0.464055850837833 1 2.8921654737929 -4.14208976759237 1.61525869341874e-06 135.048236914414 29.4726025076622 4.58216192069582 5.72113820906652e-06 -513.265016435375 221.654249901809 -2.31561098721431 0.0209532893724551 ZNF281 other 0.0105831749592796 1 0.0524742796535581 4.58216192069582 -2.31561098721431 3.34029899875922e-15 573.230958488462 69.0098097195962 8.3065141146982 7.90187347430401e-16 971.239214120602 491.84081541193 1.97470235020484 0.0488081160284196 ARPC5 other 3.47157274941045e-11 1 1.02526808329095e-11 8.3065141146982 1.97470235020484 0.000973153096027672 -1.45872628852873 8.16951234046675 -0.178557327259682 0.858352024864041 286.258450253701 76.4320931642759 3.74526508960633 0.000199495421903372 CADM3 other 1 1 1 -0.178557327259682 3.74526508960633 0.389230730699637 -2.36521605973915 2.50559072624919 -0.943975420630573 0.345599723331145 -17.0721943566861 15.918200004979 -1.07249527907339 0.283971428678954 NLRP3 other 1 1 1 -0.943975420630573 -1.07249527907339 1.63355875649518e-12 138.855112933134 18.4443005729274 7.52834797850486 2.14770775063176e-13 -4.18309889737646 115.000683348104 -0.0363745568773215 0.97099704479557 ZNF496 other 1.53113462246293e-08 1 2.65499632133098e-09 7.52834797850486 -0.0363745568773215 0.0793318140279633 6.46250833540871 4.47113904775461 1.44538299220512 0.148922981634757 -45.5613419466184 28.6921084974491 -1.58793983198094 0.112877774407499 TRIM58 other 1 1 1 1.44538299220512 -1.58793983198094 1.52160956048796e-10 322.71581460158 47.1840139902721 6.83951591460858 2.15465729710581e-11 241.533003753111 463.748581363606 0.520827477343234 0.602700058740487 IGSF8 other 1.30204130090955e-06 1 2.53150685836962e-07 6.83951591460858 0.520827477343234 0.00547744831695726 210.848731223096 75.2182759571098 2.80315825562558 0.00524376562538845 -1267.55791280774 694.397009366354 -1.82540808170301 0.0684957850685808 DDR2 other 1 1 1 2.80315825562558 -1.82540808170301 6.05670369041128e-08 632.780194110322 108.598744807371 5.82677263197405 9.71103520823109e-09 -614.115683362953 1038.88310183219 -0.59113068860191 0.554679749036946 PEA15 other 0.000445591690503558 1 0.00010397605397453 5.82677263197405 -0.59113068860191 1.94270838318245e-16 342.338833851002 38.9831266570144 8.78171822550318 2.130562352502e-17 -216.491876996452 375.818154677242 -0.5760548667011 0.564818095907426 PEX19 other 2.098707866352e-12 1 2.83812210976792e-13 8.78171822550318 -0.5760548667011 7.04354295633674e-24 637.200297810205 59.7689408521858 10.6610605562856 3.28932469939818e-24 -1192.71934675805 570.70944754321 -2.08988891263754 0.0370958883536123 NCSTN other 8.9460039088433e-20 1 4.68827449405222e-20 10.6610605562856 -2.08988891263754 4.53221559761007e-10 250.536171599691 37.5459651154246 6.67278549983967 6.23269314055244e-11 177.296620022484 358.504131070965 0.494545542593452 0.621122082844197 VANGL2 other 3.78394680244465e-06 1 7.21870519538784e-07 6.67278549983967 0.494545542593452 0.221500140084479 -4.90460481495689 4.03861328223094 -1.21442794152541 0.225115151663026 48.1180001964765 38.5623206388974 1.24779835339941 0.212645725602962 SLAMF6 other 1 1 1 -1.21442794152541 1.24779835339941 0.132884826334621 -26.1791800613036 38.1104822900244 -0.686928595184851 0.492423157452473 -738.34129473186 398.897126014881 -1.85095666671791 0.0647226589477488 OLFML2B other 1 1 1 -0.686928595184851 -1.85095666671791 0.578779693253637 -12.2131346402303 20.4922169448523 -0.595988939268883 0.55143234004676 -181.93676191361 219.668620210787 -0.828232825148305 0.40790455361453 FCRLB other 1 1 1 -0.595988939268883 -0.828232825148305 0.598170865308607 3.46736393069613 5.68109800308278 0.610333412452066 0.541898211705237 49.6237333565973 62.3387489440047 0.796033513620419 0.426363000076065 FCGR3B other 1 1 1 0.610333412452066 0.796033513620419 6.37558004919363e-08 43.8198514563964 7.74508783955587 5.65776042365831 2.49698226758791e-08 123.806143529969 87.5719222141837 1.41376528457561 0.158010272119683 KLHDC9 other 0.000468158843012288 1 0.000262982172422359 5.65776042365831 1.41376528457561 4.9194862591404e-06 53.1784639596357 10.6513733141067 4.99263920167045 8.07229162643092e-07 43.6999029788269 72.1228982292159 0.605908859069182 0.544832246185416 C1orf74 other 0.0307369501471092 1 0.00781397829438513 4.99263920167045 0.605908859069182 9.75271726397154e-21 127.187654564093 12.7141503664869 10.0036298846478 1.04006593212854e-21 44.7423499989062 78.6880305885691 0.568604267564499 0.569863767834048 FLVCR1 other 1.17227661512938e-16 1 1.45193204125144e-17 10.0036298846478 0.568604267564499 0.270079245707368 107.025724646299 88.4433218023939 1.21010521162268 0.226769929424677 -492.566556953551 542.99094412043 -0.907135859791254 0.364741076924062 ATF3 other 1 1 1 1.21010521162268 -0.907135859791254 2.5728142400147e-07 40.8140592993388 7.64178651735091 5.34090545537608 1.36126710327751e-07 13.1035026771022 16.5454565092753 0.791969848021804 0.428723457015886 RBM15 other 0.00180431462652231 1 0.00137869132219946 5.34090545537608 0.791969848021804 6.49659493140754e-10 93.5197149603091 44.3376272578072 2.1092629611532 0.0353781904044893 -477.211997493438 98.8612625905047 -4.82708782984199 1.80263710948039e-06 DENND2D other 5.37073502979461e-06 0.02261949044976 1 2.1092629611532 -4.82708782984199 0.174898371073719 17.5893977309766 9.66661743350217 1.81960213611185 0.0693711377594599 38.5307455859763 68.1503800949015 0.565378293302562 0.57205044251698 TDRD5 other 1 1 1 1.81960213611185 0.565378293302562 0.208000062120565 44.8189804232318 25.3797441509251 1.76593507628398 0.0779696683593272 45.8861113650912 178.507768737752 0.257053862078703 0.797234746465089 IER5 other 1 1 1 1.76593507628398 0.257053862078703 3.14990551520475e-09 -31.7473700969774 46.8808367671537 -0.677192906232866 0.498570910629599 -561.135287073914 91.1048370503599 -6.15922606572179 1.42046209444464e-09 SNED1 other 2.51110467672122e-05 1.98324917626361e-05 1 -0.677192906232866 -6.15922606572179 3.00759586831502e-19 170.603778160518 18.0570479439906 9.44804370513375 1.08667904197187e-19 -97.6435766491833 114.014535143345 -0.85641340839938 0.392154730872685 BPNT1 other 3.50204462906601e-15 1 1.48907629121405e-15 9.44804370513375 -0.85641340839938 2.99488125196778e-05 24.2778388645622 5.92338023136226 4.09864602917425 4.80092679400482e-05 -60.7974048814896 36.8122223246592 -1.65155486526451 0.0992121173546635 SPATA17 other 0.173733061426651 1 0.40827081456217 4.09864602917425 -1.65155486526451 0.0131934605937104 118.209099480374 47.7274532017712 2.47675271883117 0.0135669699438 -409.788820082327 302.225781099491 -1.35590292327651 0.175703153120503 C1orf115 other 1 1 1 2.47675271883117 -1.35590292327651 6.20683467157924e-20 341.446118233037 35.9607987434686 9.49495367632936 7.1421605423924e-20 -315.040534424079 222.487558366511 -1.41599169291571 0.157356605501983 BROX other 7.34020268260961e-16 1 9.80832907286748e-16 9.49495367632936 -1.41599169291571 0.150158544192498 39.6484492619079 31.1298656622066 1.2736466546993 0.203334587994457 -280.087634768642 195.811375541219 -1.43039511363671 0.153179880645384 KIF26B other 1 1 1 1.2736466546993 -1.43039511363671 7.95660073494069e-28 111.428436739922 9.43392047089821 11.8114666202304 8.61002494498808e-29 -28.4247603327526 59.1067868888081 -0.48090518583298 0.630779033813001 TFB2M essential 1.06570710243796e-23 1 1.25852734620891e-24 11.8114666202304 -0.48090518583298 1.31986597555014e-13 127.036729718398 16.6400792072796 7.63438251320483 1.04169643095963e-13 -186.158242384674 103.818678945121 -1.79310933520045 0.0735170225064593 CNST other 1.29333666944158e-09 1 1.29670371725855e-09 7.63438251320483 -1.79310933520045 4.39179394767791e-14 81.9671645359883 10.7397719111201 7.63211409090712 1.03652390842542e-13 -58.187266226267 38.5385258856693 -1.50984670246311 0.131661007101796 PPP1R21 other 4.37774020704534e-10 1 1.2903686135988e-09 7.63211409090712 -1.50984670246311 0.897478616550411 0.00441655425811065 2.88276816896476 0.00153205322080987 0.998778161537797 12.2954641714952 26.4638346372895 0.464613852830307 0.642394245989078 KLHDC8A other 1 1 1 0.00153205322080987 0.464613852830307 0.999057703068603 1.22971977800894 35.1686940541369 0.0349663190824196 0.972119447679801 -2.11635994847514 111.875934711087 -0.018917025846001 0.984914246121787 PKDCC other 1 1 1 0.0349663190824196 -0.018917025846001 0.118241395654057 8.05650466059411 3.9378240981647 2.04592802008322 0.0412446439262354 0.369608794288709 12.7138710399021 0.0290713027628409 0.976818404589721 OXER1 other 1 1 1 2.04592802008322 0.0290713027628409 0.725843594434471 13.7110261800115 18.3120428036964 0.748743672510632 0.454335916006288 -9.13796763145135 59.1232479865902 -0.154557943662431 0.87722725706731 HAAO other 1 1 1 0.748743672510632 -0.154557943662431 2.27933895692079e-12 60.2213450468077 8.02644037822667 7.50287078817283 2.56834904271007e-13 9.0327856428184 50.1168800495538 0.180234396751895 0.857035798547509 B3GALNT2 other 2.12320423837171e-08 1 3.16908588379996e-09 7.50287078817283 0.180234396751895 1.48299513358004e-11 734.663594521103 106.064916045064 6.92654670286038 1.2397586713311e-11 -1693.29784572173 829.490002909424 -2.04137221640106 0.0417030163341787 MAPKAPK2 other 1.33217452849495e-07 1 1.46737836338749e-07 6.92654670286038 -2.04137221640106 0.212290359666575 12.5507282729881 10.8975238875432 1.15170458927231 0.2499559367273 -113.365801295283 85.2250438527961 -1.33019352258819 0.1840202168496 IL20 other 1 1 1 1.15170458927231 -1.33019352258819 0.00600648574281853 7.26430885225691 2.88609186986346 2.51700541071154 0.0121263490494135 -44.8653411805119 22.570935261126 -1.98774843228511 0.0473478675184088 IL24 other 1 1 1 2.51700541071154 -1.98774843228511 0.00760886985889285 17.4734670436869 8.11345474485471 2.15364078474315 0.0317135892719277 -144.606117561989 63.6285067841793 -2.27266244126201 0.0234416188046711 FCMR other 1 1 1 2.15364078474315 -2.27266244126201 0.173121092059507 245.65093991218 133.933595974422 1.8341248745318 0.0671896512985481 422.624851570849 1050.77247153871 0.402203962340175 0.687694264842342 PIGR other 1 1 1 1.8341248745318 0.402203962340175 2.79526622369875e-08 749.451274382413 126.80323532589 5.910348205677 6.09015819397277e-09 -385.098358744095 791.309335833972 -0.486659693377982 0.626699188494614 CAPN2 other 0.000210511499306753 1 6.5755438020324e-05 5.910348205677 -0.486659693377982 9.2051939356066e-11 162.765245780079 23.6167340937156 6.89194556428487 1.61080061053827e-11 -42.9123739632935 144.391555345954 -0.297194485234805 0.76643763359822 MRPL55 essential 7.95236704097054e-07 1 1.90010040019094e-07 6.89194556428487 -0.297194485234805 7.8235980298398e-17 516.502796526297 60.0865081251663 8.59598623122463 9.12374305232627e-17 -624.16134051689 370.972662042938 -1.68249955961619 0.0930554865225217 WDR26 essential 8.55197500641789e-13 1 1.20387789575445e-12 8.59598623122463 -1.68249955961619 0.19949353903869 -30.971097863578 46.5807786858392 -0.664890084222516 0.506404119334937 -298.103043829088 169.374209345812 -1.76002618687034 0.0789684513922009 REL other 1 1 1 -0.664890084222516 -1.76002618687034 1.09528933970543e-09 38.981521116232 6.88611595198762 5.66088654156053 2.44591181576971e-08 -56.8936152314037 25.0388782183682 -2.27221102859422 0.0234653884711708 PUS10 other 8.94522803737424e-06 1 0.000257725728027654 5.66088654156053 -2.27221102859422 1.01761238461427e-19 214.316160001198 24.3733553577581 8.79305113536538 1.94210047667747e-17 -232.833184205726 88.62492017721 -2.62717510763523 0.00885389795707197 PEX13 other 1.19854386659868e-15 1 2.58940256555407e-13 8.79305113536538 -2.62717510763523 1.13125812887802e-10 81.428929611464 12.385300691071 6.57464292894954 1.15030585938804e-10 -44.1311750567542 45.034681068954 -0.979937550555397 0.327554950872026 KIAA1841 other 9.72881990835096e-07 1 1.32308179946813e-06 6.57464292894954 -0.979937550555397 0.00999299540130945 20.1323110415524 7.04321646321011 2.85839731700886 0.00442226657610829 -36.0940117046685 41.4951524136864 -0.86983682683772 0.384776058977481 TRIM17 other 1 1 1 2.85839731700886 -0.86983682683772 0.0878843690937511 -7.53255290369054 4.95573670262406 -1.51996632502733 0.129109082205371 -24.1496989674599 12.6673692774233 -1.90644943228278 0.0571264050538419 RFTN2 other 1 1 1 -1.51996632502733 -1.90644943228278 0.00133720636232626 12.7726741319901 4.44132569935985 2.87586972822802 0.00418677384246667 64.2957972593191 26.6327801003159 2.41416018219429 0.0161000372874463 DISC1 other 1 1 1 2.87586972822802 2.41416018219429 1.52924078696138e-05 -74.9013698938779 61.1910260911994 -1.22405807972961 0.221457273246722 -914.383726236816 192.444498388809 -4.75141525942416 2.58492216599669e-06 CAPN13 other 0.0915250610996388 0.0322236397213148 1 -1.22405807972961 -4.75141525942416 1.33970959143565e-23 108.670679122475 10.2377217597265 10.6147326204906 4.71279664362879e-24 14.4930265215565 32.1882636303458 0.450258103015319 0.65270339467328 MEMO1 other 1.69459866220695e-19 1 6.71149370019176e-20 10.6147326204906 0.450258103015319 6.86891373254441e-26 274.853847869893 25.3390831790709 10.8470320700834 5.91462949040452e-25 -77.3997308570536 79.6682219600567 -0.971525772168727 0.331717499535524 DPY30 other 8.99278185864714e-22 1 8.47093235615736e-21 10.8470320700834 -0.971525772168727 1.38951116602444e-10 24.0636636648616 5.29089134971384 4.54813037621026 6.69334641153573e-06 -50.5323869875598 13.1918402850144 -3.83057904703131 0.000142910704359138 TYW5 other 1.19025526481653e-06 1 0.0611035593909097 4.54813037621026 -3.83057904703131 1.41036121657754e-16 62.7228943055317 8.22542337971153 7.62549128598551 1.10858089774584e-13 -48.7514952850907 20.5085427633374 -2.37713112275547 0.017796556215831 MAIP1 other 1.52995984774332e-12 1 1.37896377870605e-09 7.62549128598551 -2.37713112275547 0.0393205339220371 -109.959812951895 48.9476360419854 -2.24647851956681 0.0250751760501466 -254.678022616592 144.282594401112 -1.76513337366651 0.0781044326055378 KCNF1 other 1 1 1 -2.24647851956681 -1.76513337366651 0.000126066599417726 -18.2750542574156 36.3194316434104 -0.503175667418003 0.615044809411775 -457.176449829099 108.155261800114 -4.22703844658086 2.777930932329e-05 PQLC3 other 0.677607971870276 0.325795739743545 1 -0.503175667418003 -4.22703844658086 3.5173961421123e-06 84.8567772889526 35.4247880034157 2.39540677789718 0.0169479236906715 -289.26005727261 84.8424053390576 -3.40938067605031 0.000700687960989287 ARL5A other 0.0223038089371341 1 1 2.39540677789718 -3.40938067605031 0.0383285824753823 169.116905435433 68.8216993860494 2.45731952195465 0.0143099498017255 -13.2122437103621 201.005857018983 -0.065730640421659 0.947616514807638 FAM84A other 1 1 1 2.45731952195465 -0.065730640421659 0.19094592564983 -293.054169148414 287.211828867612 -1.02034157264287 0.308023392580613 -1239.40849336683 706.448868191791 -1.75442066534721 0.0799256196072789 KCNJ3 other 1 1 1 -1.02034157264287 -1.75442066534721 0.000306255777847635 1.69836560377259 2.65702020660107 0.639199355561237 0.522962797610324 -36.0496433192188 9.32337624124833 -3.86658677998304 0.000123738840267773 CLHC1 other 1 1 1 0.639199355561237 -3.86658677998304 0.0347545451029484 1.49255933122487 1.20328121527809 1.24040773866808 0.215360319502995 -8.7841041124979 4.22226502688714 -2.08042461962033 0.0379548814031967 PRORSD1P other 1 1 1 1.24040773866808 -2.08042461962033 0.208620882315241 -63.5675875442181 36.0114385259344 -1.76520544988611 0.0780943945792558 -58.8628257627309 97.2058539940389 -0.605548157278066 0.545069250982099 FRZB other 1 1 1 -1.76520544988611 -0.605548157278066 0.00123358996715919 1.72180475961679 2.92106375600925 0.589444429644738 0.555809702651133 -26.5690021387784 7.88484183350312 -3.36963032357672 0.000806461912213503 DUSP19 other 1 1 1 0.589444429644738 -3.36963032357672 0.0163127492251027 50.9105857430666 23.0325594122941 2.21037466274339 0.0274945965824796 -124.453490761419 81.6596116020312 -1.52405195567111 0.128076835636462 CFAP36 other 1 1 1 2.21037466274339 -1.52405195567111 2.52800773286716e-10 39.8799941540325 7.57078431808665 5.26761726110186 2.00096149301049e-07 -57.9394033459404 20.562752824697 -2.81768709860442 0.00501462414435603 NUP35 other 2.14021134664534e-06 1 0.00200916543513183 5.26761726110186 -2.81768709860442 2.30834147069412e-16 50.8240374939496 5.81419606741048 8.74136972759254 2.87763428602755e-17 17.2705261463878 17.5068346871034 0.986501926536743 0.324326233170197 CCDC138 other 2.48954627614361e-12 1 3.82754136384524e-13 8.74136972759254 0.986501926536743 0.00629491467333745 44.5225555404727 18.5893755949576 2.39505384745411 0.0169551280065931 -108.600057528102 63.23820368083 -1.71731724190362 0.0864903612969299 FBXO41 other 1 1 1 2.39505384745411 -1.71731724190362 0.032943261055852 909.217943590538 355.575771770765 2.55703007846299 0.0108277235591382 -208.716314906542 1220.07729422452 -0.171068108467015 0.864233938329173 ACTG2 other 1 1 1 2.55703007846299 -0.171068108467015 1.40507140425348e-14 48.4698205327595 6.39043580964077 7.58474413585952 1.46205415736241e-13 -20.3330972555638 18.4062876738003 -1.10468213992472 0.269788404831988 WDCP other 1.42670950387899e-10 1 1.81397059303954e-09 7.58474413585952 -1.10468213992472 1.94805031580638e-13 235.828116378602 30.5525525992386 7.71876967112983 5.67665218244196e-14 42.4415444630513 88.3875773603367 0.48017544694122 0.631296017576289 SMC6 essential 1.89584256734277e-09 1 7.11114218894504e-10 7.71876967112983 0.48017544694122 0.0793605189260507 39.968599181403 17.8983151009656 2.23309283337217 0.0259502678579168 44.5855957793642 51.9931668041622 0.857527989154819 0.391532170132516 VSNL1 other 1 1 1 2.23309283337217 0.857527989154819 0.0876224059138096 -353.04225897264 197.861728314356 -1.78428775478873 0.0749382724664399 -917.010368105355 523.323499112099 -1.75228203904699 0.080292877770393 CCDC74A other 1 1 1 -1.78428775478873 -1.75228203904699 4.44809175560324e-16 744.944328816841 86.7774030424413 8.58454278071104 9.67967893480476e-17 -441.529768441679 546.896477233423 -0.807337013167901 0.419826494158657 H3F3A essential 4.75323085003762e-12 1 1.2764592611327e-12 8.58454278071104 -0.807337013167901 2.08222642557237e-06 250.052057676331 48.8863313057506 5.11496876524497 4.36358159268551e-07 -131.293531045103 310.994543794294 -0.422173101313142 0.673066393575592 COQ8A other 0.0135170101169717 1 0.00429812786879523 5.11496876524497 -0.422173101313142 0.123986189094193 28.6331549355995 21.4452863325027 1.33517242398404 0.182378354371374 -45.4322463202644 43.587083741406 -1.04233278348709 0.297720407321784 SLC16A14 other 1 1 1 1.33517242398404 -1.04233278348709 3.16280069306999e-06 170.364544664717 64.0047682153858 2.66174770122461 0.00800430496336116 761.9299933776 155.933385377848 4.88625313643603 1.35529654748943e-06 EN1 other 0.020153366016242 0.0171117809803092 1 2.66174770122461 4.88625313643603 0.249326999259427 74.0335591400473 51.6240571352797 1.43409029139349 0.152151039345566 -31.071655475214 124.077473932597 -0.250421406000684 0.80236096015739 SGCB other 1 1 1 1.43409029139349 -0.250421406000684 2.06622513955959e-05 -74.1630986226407 23.9544867728667 -3.09600031617649 0.00206788680234942 -255.307145128795 57.5741693517129 -4.43440431713669 1.12846690672926e-05 SPATA18 other 0.121989932239598 0.135810992224866 1 -3.09600031617649 -4.43440431713669 2.94141142783087e-09 -168.970435805116 45.299152467772 -3.73010148314209 0.000211609262787549 -726.693420501142 120.378882323032 -6.03671845491211 2.92273735427827e-09 NOSTRIN other 2.34842288398017e-05 4.05062169929425e-05 1 -3.73010148314209 -6.03671845491211 0.269495177774981 -2.42098931715615 3.50731762442411 -0.690268055649413 0.49032164524731 -13.4424544346691 8.42106775983732 -1.59628859641533 0.11100830954039 CFAP221 other 1 1 1 -0.690268055649413 -1.59628859641533 0.23666364672653 40.8526621681906 25.0735363841413 1.62931393251849 0.10382653081341 48.6632045592612 55.4891861177757 0.876985372536798 0.380882408096587 SGPP2 other 1 1 1 1.62931393251849 0.876985372536798 0.215981580424995 162.542299420375 96.229249219031 1.68911532345438 0.0917756627415373 -3.37212739573368 230.808032204875 -0.0146100955132291 0.988348651228497 INHBB other 1 1 1 1.68911532345438 -0.0146100955132291 0.759873869211347 299.396489264817 473.467900951923 0.632348019079795 0.527438499213803 -221.82103283597 1221.86364851612 -0.181543196825079 0.85601224501525 XIRP2 other 1 1 1 0.632348019079795 -0.181543196825079 3.56961682841025e-12 -14.5470283911984 9.01585052421959 -1.61349485022187 0.107215867546544 -173.836762471552 23.4222529597564 -7.42186342066385 4.46538488584855e-13 BBS5 other 3.30153860459664e-08 6.58465655267227e-09 1 -1.61349485022187 -7.42186342066385 1.1225824323888e-16 186.214214328758 30.5363724875235 6.09811183056669 2.04370916477275e-09 -267.583493025241 70.382898817625 -3.80182540816625 0.000159974247753934 SMARCAD1 other 1.2219309776552e-12 1 2.24521888841935e-05 6.09811183056669 -3.80182540816625 5.09491097111769e-06 -14.1052774224844 4.47260789836082 -3.15370310633622 0.00170161212580532 -48.9593834044788 10.3088573893267 -4.74925411764536 2.61853946012825e-06 HPGDS other 0.0317565800829766 0.0326322387521182 1 -3.15370310633622 -4.74925411764536 0.0143337151445684 565.769517735273 269.201629875452 2.10165710362538 0.0360451340074178 -697.588292513645 619.165143518416 -1.12665950242223 0.260385961425618 PDLIM5 other 1 1 1 2.10165710362538 -1.12665950242223 0.613050065676675 4.6457545227159 4.69704348862076 0.989080585259831 0.323085491105408 2.46896995276589 17.8390055347618 0.13840289179544 0.889975797767595 NEURL3 other 1 1 1 0.989080585259831 0.13840289179544 1.42581666960144e-13 258.023994058974 32.5996437503757 7.91493293714291 1.5126411730034e-14 -152.712515107572 396.751443311773 -0.384907270488663 0.700464104431406 RPRD2 other 1.39444870287021e-09 1 1.91757521501641e-10 7.91493293714291 -0.384907270488663 0.393593222743916 76.5279841205845 67.3157884756196 1.13685044554297 0.256124418117712 -136.323487915475 253.188284982184 -0.538427312800304 0.5905124705025 ANKRD23 other 1 1 1 1.13685044554297 -0.538427312800304 0.00230712020307646 91.047988947734 58.423002322281 1.55842708057834 0.119739247921197 2023.34722402627 668.595375205451 3.02626565941251 0.00259833448591098 CTSS other 1 1 1 1.55842708057834 3.02626565941251 0.693535085257135 -0.767319191220164 7.36372139524949 -0.104202637502714 0.917046735692255 -11.2362930212866 14.2492809148819 -0.788551582947001 0.430715750917051 MSX1 other 1 1 1 -0.104202637502714 -0.788551582947001 2.63178096794802e-17 24.4163036958832 7.03072903302662 3.47279828040427 0.000555970067467876 -69.3782263127802 12.743225830928 -5.44432212324123 7.87590218179633e-08 PACRGL other 2.91759238106717e-13 0.00104639236387346 1 3.47279828040427 -5.44432212324123 0.0416426283884554 63.1854398947677 29.1327370879658 2.16888099816987 0.0305356663857416 420.950785180604 358.908595091099 1.17286348373395 0.241377417006167 BNIPL other 1 1 1 2.16888099816987 1.17286348373395 0.141535910918792 -14.6668776637807 11.2163838706647 -1.30762978807639 0.191552269990404 -41.4577767154716 21.4004770555913 -1.93723610028777 0.0532347609102978 C1QTNF7 other 1 1 1 -1.30762978807639 -1.93723610028777 0.356465691993944 -1.72437692527779 2.12594882338386 -0.81110932977827 0.417664927894349 31.1824267772649 25.1203991439717 1.24131892166801 0.215033972120433 TNFAIP8L2 other 1 1 1 -0.81110932977827 1.24131892166801 2.47749827190867e-17 49.4872610752612 5.61637652127136 8.81124349263873 1.7467523289412e-17 100.639385019499 66.3636012331672 1.5164846866267 0.129989675666389 LYSMD1 other 2.74754558354671e-13 1 2.33016760680757e-13 8.81124349263873 1.5164846866267 0.968246011648438 2.39101999382935 10.6697858739173 0.224092593992377 0.822770965837518 -17.0501659872149 126.095077195366 -0.135216745700533 0.892491459925939 TMOD4 other 1 1 1 0.224092593992377 -0.135216745700533 1.60236824519956e-24 218.748574483562 20.0516040832568 10.9092805530815 3.74594949664995e-25 200.162339534937 236.969007124124 0.844677293305669 0.398669308570769 VPS72 essential 2.05631916906459e-20 1 5.3709423882967e-21 10.9092805530815 0.844677293305669 6.66853582413948e-16 152.845036618536 24.7210196355364 6.18279661890732 1.24309215426744e-09 -226.041509301905 58.5977063079663 -3.8575146288819 0.000128372574993718 ERCC3 other 7.0906541418075e-12 1 1.37834058065174e-05 6.18279661890732 -3.8575146288819 3.91774127466349e-23 174.55481327366 20.3969795329855 8.5578755909116 1.17762140819058e-16 -363.298378746778 77.0135956541905 -4.71732783881531 3.04164771925986e-06 RNF149 other 4.92146658923227e-19 0.0377650980823305 1.5503385838829e-12 8.5578755909116 -4.71732783881531 1.65912614203559e-28 238.102076389704 25.3138796463918 9.40598911410415 1.45574644726682e-19 -288.512720499113 64.9152745232208 -4.44445044125801 1.06943762655158e-05 IWS1 other 2.23816116560601e-24 0.128888622751997 1.99291688630827e-15 9.40598911410415 -4.44445044125801 1.75180481770289e-14 71.0487868852452 8.7851454269792 8.08737743453332 4.01171387700711e-15 -1.85868806763013 29.7283738823761 -0.0625223591099953 0.95016990624819 BOLA3 other 1.77317683647887e-10 1 5.13940664783381e-11 8.08737743453332 -0.0625223591099953 0.027770569764986 130.002916859797 51.2643548065859 2.5359319813988 0.0114945644138323 -59.2793278586974 163.020595509375 -0.363630912238253 0.716275431882752 CDC42EP3 other 1 1 1 2.5359319813988 -0.363630912238253 6.06604685073866e-12 1652.85262495713 225.804514326496 7.31983871043089 8.89694931259873e-13 1102.50927337857 3091.3666520437 0.356641381458164 0.721497571774594 S100A11 other 5.55710551996168e-08 1 1.08195800590513e-08 7.31983871043089 0.356641381458164 0.0700561964601359 7.22023162615069 3.21139927842695 2.24831327410879 0.0249550353706542 -23.9487635765155 37.3650287591377 -0.640940589953616 0.521830697485945 IVL other 1 1 1 2.24831327410879 -0.640940589953616 0.393906842675039 -5.12103203574453 4.20008139955198 -1.21926971136578 0.223270237547295 -27.1997104287162 48.6960099665753 -0.55856137797298 0.576690933345181 SPRR3 other 1 1 1 -1.21926971136578 -0.55856137797298 2.98427121379551e-16 137.648143379391 16.6287092153777 8.27774071917132 9.86388562401412e-16 -60.0827974555503 52.2268514909113 -1.15041967379569 0.25047930634705 DHX57 other 3.20659941922328e-12 1 1.27717591059735e-11 8.27774071917132 -1.15041967379569 0.770194703074826 -2.14480331746638 3.19430290277422 -0.671446441601905 0.502221182033357 -8.737056645205 37.0349503241404 -0.235913821099686 0.813588333856523 SPRR2D other 1 1 1 -0.671446441601905 -0.235913821099686 0.206951727293872 10.1614801066741 12.4196432098153 0.818178101818858 0.413611762169106 69.3781848141202 41.0538039620579 1.68993316376333 0.0916105134332891 ARHGAP25 other 1 1 1 0.818178101818858 1.68993316376333 0.00278454202124623 1201.00389140845 515.509933195451 2.32973957255077 0.0201869452159728 13650.4045582199 5663.82505678048 2.41010349390615 0.016280667747679 S100A9 other 1 1 1 2.32973957255077 2.41010349390615 0.141602826609304 50.749505865714 35.9817687644576 1.41042276709431 0.158986417749624 -138.042366749696 121.081875670564 -1.14007456512548 0.25475693746626 TGFA other 1 1 1 1.41042276709431 -1.14007456512548 0.0510094769538902 2.15698958391648 0.882275991525912 2.44480140526768 0.0148177996092487 -2.93802276069059 9.12680335313007 -0.321911478423931 0.747646682802722 TDRD10 other 1 1 1 2.44480140526768 -0.321911478423931 7.64665688354195e-05 58.7398827642566 14.0090289310123 4.19300174576856 3.21419319625545e-05 -5.18521131789047 34.3543884273261 -0.15093301191664 0.880084611985774 FZD5 other 0.422401326246858 1 0.278124137271984 4.19300174576856 -0.15093301191664 1.84250205085806e-16 91.9726088308461 54.2633693004317 1.69492993185947 0.0906609869405782 -668.734406760079 100.269181030665 -6.66939133127619 6.32708120046236e-11 DCAF16 other 1.99137621656739e-12 9.07240173334298e-07 1 1.69492993185947 -6.66939133127619 0.636735828110608 2.22770151304774 8.03265031652624 0.277330821741923 0.781631063541174 15.3507459204865 16.152678738064 0.950352951941785 0.342353413455969 NPPC other 1 1 1 0.277330821741923 0.950352951941785 5.44465449256565e-15 19.2413258222433 16.5952005344987 1.15945123906419 0.24678471927651 -241.739957483975 35.1036512591004 -6.88646191530592 1.59521722201831e-11 GNPDA2 other 5.61725003997998e-11 2.30955549403811e-07 1 1.15945123906419 -6.88646191530592 0.0130584007079117 48.8389235523929 69.259321436248 0.705160295244133 0.481014532712372 -391.35011228384 163.740741301055 -2.39005948778686 0.0171874880746241 PAQR3 other 1 1 1 0.705160295244133 -2.39005948778686 4.46766999375835e-05 38.8706414983193 10.0226970517342 3.87826163932528 0.000118252532806388 83.9943895254184 22.3362551060021 3.7604508511746 0.000188233213158307 NIPAL1 other 0.254567836244351 1 0.969907274077995 3.87826163932528 3.7604508511746 0.185008611510953 32.6059537507893 48.9558265863503 0.66602805068111 0.505679173805147 -149.920153563076 113.381517719774 -1.32226271598876 0.186643587871992 ANTXR2 other 1 1 1 0.66602805068111 -1.32226271598876 7.7590066985514e-24 26.8864602258307 4.91237580420756 5.47320915529342 6.77587541064031e-08 -75.7573607189226 11.5597503035864 -6.55354646331929 1.31341022815646e-10 HELQ other 9.84850720247129e-20 1.87344834944237e-06 0.000699134824869867 5.47320915529342 -6.55354646331929 1.77758261670428e-22 64.911706773729 9.62353607426213 6.74509933488309 3.94507923412138e-11 -109.577063906638 22.6460023601496 -4.83869347728506 1.70788099270637e-06 MRPS18C other 2.20935743430175e-18 0.0214526931493847 4.595622799828e-07 6.74509933488309 -4.83869347728506 2.286911979882e-14 123.532435150563 64.3280230422362 1.92035180483402 0.0553959630686786 -880.456474928228 134.026271847 -6.56928274430647 1.29851867615011e-10 CGGBP1 other 2.30314905493916e-10 1.85272644713097e-06 1 1.92035180483402 -6.56928274430647 0.00804320054201761 91.0466388559631 32.9213266460779 2.76558231795346 0.00587585136996309 -45.2153626801398 80.2849062902108 -0.563186341859789 0.57354090326609 GPR155 other 1 1 1 2.76558231795346 -0.563186341859789 0.768716966017936 5.94415985020165 9.38696280388614 0.633235688090807 0.526845368659102 12.4737655080075 23.3088430806293 0.535151636006069 0.592763287685018 DAPL1 other 1 1 1 0.633235688090807 0.535151636006069 8.8687155426341e-14 281.882585878938 36.1603005683128 7.79536069802337 3.4121180367838e-14 400.856665049109 394.442273807809 1.01626192643952 0.30996749122139 PMVK essential 8.7401191672659e-10 1 4.29688024372183e-10 7.79536069802337 1.01626192643952 3.36162678417956e-14 535.815676032797 66.1179579568446 8.10393564154726 3.68502323524666e-15 -231.346567606691 721.225135470266 -0.320768864296228 0.748511755580841 PBXIP1 other 3.36868620042634e-10 1 4.72456828990975e-11 8.10393564154726 -0.320768864296228 5.87233005156722e-07 516.288516320648 95.5082722064157 5.40569423353014 9.71862298874156e-08 166.453376021019 401.857697210774 0.414209749312614 0.678885589850201 CLDN1 other 0.00400023123112759 1 0.000993632014368938 5.40569423353014 0.414209749312614 8.53192594882953e-29 421.358646546665 34.8323612695229 12.0967580488245 6.3658969426116e-30 -340.05926457936 379.722600430082 -0.895546549492186 0.370900771221155 PYGO2 other 1.15454021939561e-24 1 9.35341237777922e-26 12.0967580488245 -0.895546549492186 1.62429741363069e-107 793.245669408438 28.1005882042282 28.2287923527907 1.91634264092212e-108 6.4306198705033 153.321033777169 0.0419421896140442 0.966560257948596 HIPK1 other 2.53926414672885e-103 1 2.99715989040219e-104 28.2287923527907 0.0419421896140442 6.68627815895526e-05 7.26288920638015 1.76347708117027 4.11850501712241 4.42551316377747e-05 24.0497663631245 19.1846385555845 1.25359496836201 0.210544043803739 DCST2 other 0.372024516764271 1 0.377717548528407 4.11850501712241 1.25359496836201 4.22820082376381e-07 4.83640369322708 0.997599770456044 4.84804010231093 1.64567939394094e-06 24.2367423691085 10.7438721842594 2.25586659571556 0.0244905172948925 DCST1 other 0.00291576728806752 1 0.0156240801660753 4.84804010231093 2.25586659571556 0.001131560688008 -4058.61368548456 1856.19150629148 -2.18652745243584 0.0291992114406217 -12821.0489906422 3602.29501535247 -3.5591335345941 0.000404380851363903 COL6A3 other 1 1 1 -2.18652745243584 -3.5591335345941 7.41762887141056e-21 340.828450582895 33.9650132793495 10.0346921044814 9.55715903055457e-22 134.702593541918 336.195137277388 0.400667881852132 0.688832452633222 YY1AP1 other 8.94120984159828e-17 1 1.33469689857608e-17 10.0346921044814 0.400667881852132 0.8644329579686 0.880247427986661 2.49767003272228 0.35242742894555 0.724657045288099 2.56022504222857 4.87985701328348 0.52465165173065 0.60004350617068 KBTBD8 other 1 1 1 0.35242742894555 0.52465165173065 0.935144519089745 8.21723113801138 27.5505643105458 0.298259993711489 0.765620752129076 -3.05853484332854 54.0566272236351 -0.0565802011782056 0.954900770268717 EOGT other 1 1 1 0.298259993711489 -0.0565802011782056 0.279326886408328 33.2346749790909 57.6733417218422 0.576257140419942 0.564683728671148 180.174313478732 113.19914946114 1.59165783785844 0.112052265637503 LMOD3 other 1 1 1 0.576257140419942 1.59165783785844 4.21469093859476e-12 407.342568501712 54.9795256685925 7.40898659179247 4.91154077493179e-13 -105.917329595226 493.288917012666 -0.214716621319319 0.830069024674714 NAXE other 3.88594504538437e-08 1 6.01221706259401e-09 7.40898659179247 -0.214716621319319 1.28329606717433e-08 35.2008622039304 10.2932787562611 3.41979101484246 0.000673972042936177 -146.302093476144 32.7138342161421 -4.47217811613026 9.44031039523855e-06 POGLUT1 other 9.85186390769735e-05 0.114142792988829 1 3.41979101484246 -4.47217811613026 0.0596767683128574 13.8802274672597 10.800831505528 1.28510730494737 0.199311892678459 -34.604433831493 25.3034330609333 -1.36757861070322 0.172019304928503 SLC22A15 other 1 1 1 1.28510730494737 -1.36757861070322 0.384311214227442 -0.571123622861629 0.917802508728353 -0.622272893602068 0.534023647917399 -12.1736480030818 9.53964939133649 -1.2761106308726 0.20246197342745 IGFN1 other 1 1 1 -0.622272893602068 -1.2761106308726 3.46296866123504e-06 2043.16188483032 727.068203084518 2.81013786074319 0.00513370399321204 -4918.11538012145 1745.25335418734 -2.81799508840453 0.00501156335068659 ATP1A1 other 0.0219725361555363 1 1 2.81013786074319 -2.81799508840453 0.00233762820940427 48.0463914461953 13.7625608062084 3.4910938540247 0.000519886502284133 17.8452787722431 44.9702774460526 0.396823853125006 0.691652131779906 SLC15A2 other 1 1 1 3.4910938540247 0.396823853125006 1.02837653728973e-13 38.3303676586099 36.9083506924262 1.03852832596162 0.299488943008286 -477.532024440004 71.7913737268067 -6.65166300142401 7.11812409868604e-11 EIF4E3 other 1.01099697380953e-09 1.01981363961875e-06 1 1.03852832596162 -6.65166300142401 1.55405014050774e-11 274.491802438498 46.8118675320727 5.86372253254867 7.85815793486912e-09 -479.473786646409 150.466142363039 -3.18658921612778 0.00152222755000444 LRRC58 other 1.39398297603544e-07 1 8.44437651681035e-05 5.86372253254867 -3.18658921612778 0.267663699196139 -18.1256269931246 40.3034215717989 -0.449729236036066 0.653084498854423 -464.185467624723 294.709357471841 -1.57506185621906 0.1158224481411 LMOD1 other 1 1 1 -0.449729236036066 -1.57506185621906 0.01125653654294 368.74247071812 125.314853808809 2.94252803646649 0.00339426415589798 615.573067984357 927.074610828626 0.663995174492108 0.506974714659146 ELF3 other 1 1 1 2.94252803646649 0.663995174492108 3.55473633432965e-05 6.73561847566371 1.47602004276853 4.56336518508917 6.22537341819543e-06 3.65191846592639 3.38232891460896 1.07970530309841 0.280751014895343 TMEM169 other 0.204717265494044 1 0.0569497160296518 4.56336518508917 1.07970530309841 4.29415213029719e-05 -916.415447284831 237.432420213133 -3.85968961804881 0.000127345756056651 -2068.74223596874 574.36179801267 -3.60181029296642 0.000345342132521732 IGFBP7 other 0.245324911203878 1 1 -3.85968961804881 -3.60181029296642 8.71146679613255e-09 26.8240692427079 4.4586708388377 6.01615822568784 3.35567370147103e-09 54.4163776274837 46.2309468433284 1.1770552269218 0.239707838999796 TRIM46 other 6.76184052715809e-05 1 3.65667763249298e-05 6.01615822568784 1.1770552269218 1.69594658621771e-17 444.834464891248 48.7680076087793 9.12144019619879 1.57785591844197e-18 -259.423892707399 508.275938118422 -0.510399712541491 0.609985983657142 KRTCAP2 other 1.88741895580169e-13 1 2.13452348646829e-14 9.12144019619879 -0.510399712541491 0.0505067931201949 -6.20189570549021 4.48607280999977 -1.38247771896741 0.167392350528275 -23.7014000295379 10.2176755707414 -2.31964695545899 0.0207292795033116 CXCR1 other 1 1 1 -1.38247771896741 -2.31964695545899 6.40399043180049e-10 728.308923876487 119.258698930628 6.10696687459366 1.93382688356812e-09 -224.296486246547 270.986158069136 -0.827704587735152 0.408200766023931 ARPC2 other 5.29802128422855e-06 1 2.12701618923657e-05 6.10696687459366 -0.827704587735152 5.90501609485335e-11 3.37371554925293 0.502915582705547 6.70831381104413 4.98090137059144e-11 9.58970487153802 4.52127032359462 2.12102001985888 0.0343751570880947 TSACC other 5.15212654275955e-07 1 5.78332458139372e-07 6.70831381104413 2.12102001985888 5.33000607299227e-26 1629.81855463111 143.076633417775 11.3912280132573 4.33285555350573e-27 -303.230334688611 1286.27578646804 -0.23574286158433 0.813721588464181 CCT3 essential 6.98763796169287e-22 1 6.28004083925121e-23 11.3912280132573 -0.23574286158433 3.27514109868138e-18 204.149781904501 21.9595896603029 9.29661187037341 3.56510663637697e-19 143.818005139257 197.448245889935 0.728383301107809 0.466694721777007 TMEM79 other 3.71499254823429e-14 1 4.85710128139998e-15 9.29661187037341 0.728383301107809 3.46668498474866e-20 1218.13215130725 124.270074866229 9.80229675260528 5.62538833036751e-21 -1473.98783522913 1117.64637369942 -1.31883202944614 0.187788455271604 SSR2 other 4.11946176737683e-16 1 7.80691392488403e-17 9.80229675260528 -1.31883202944614 8.24010557072284e-17 39.4349247654992 13.3626774704573 2.95112449227959 0.00330267099870565 -222.319247548491 30.4479072738344 -7.30162653048875 1.01547869356282e-12 RNF25 other 9.00029324459371e-13 1.49194129658249e-08 1 2.95112449227959 -7.30162653048875 2.92314460708206e-16 -12.8835440665977 26.452621465057 -0.487042242055913 0.626424578038224 -514.721475344231 60.2743699605535 -8.53964090675838 1.35356921627215e-16 STK36 other 3.14179582369179e-12 2.05444735645787e-12 1 -0.487042242055913 -8.53964090675838 0.599066739127845 31.5683877401156 31.1707667982824 1.01275621303789 0.311628508356623 -7.63162964326352 251.121601122683 -0.0303901759511925 0.975767066700498 ADORA1 other 1 1 1 1.01275621303789 -0.0303901759511925 4.09768324639833e-09 -72.2436162278012 45.4961278151317 -1.58790692081214 0.112894882152846 -597.314024189039 94.9231697068338 -6.29260512511137 6.47686473491606e-10 NEK10 other 3.24618466779675e-05 9.11489174144737e-06 1 -1.58790692081214 -6.29260512511137 0.189147095790024 -3.00222077045968 3.97508816213674 -0.75525891452075 0.450422929490856 10.6008778766005 8.2397984713503 1.28654577092627 0.198803937730959 EOMES other 1 1 1 -0.75525891452075 1.28654577092627 2.63371172189636e-10 67.7608528046575 14.4587472760677 4.68649541422003 3.52116643904114e-06 -136.096878803444 38.8705186712737 -3.50128795435969 0.000501250061644561 CWC22 essential 2.22574977617462e-06 1 0.0327362843837655 4.68649541422003 -3.50128795435969 2.70772490320222e-24 132.322287381327 23.4644306630956 5.63927117095753 2.76132968961218e-08 -328.825042721225 48.254415666531 -6.81440316247153 2.54444954752877e-11 AZI2 other 3.462638606215e-20 3.67240403194827e-07 0.000290381430159617 5.63927117095753 -6.81440316247153 0.0831292727622766 -102.640250493205 166.823834840157 -0.615261305985145 0.53864329599895 -764.85244154666 343.122309769418 -2.22909563082811 0.026221257178657 TGFBR2 ts 1 1 1 -0.615261305985145 -2.22909563082811 4.24904857412556e-05 76.0565713294104 23.6233165407848 3.21955518811685 0.00136106575333307 -116.678258232676 52.9346496150404 -2.20419439972119 0.0279317684402145 ANKZF1 other 0.242875616497017 1 1 3.21955518811685 -2.20419439972119 2.74979281494362e-17 245.659822445766 45.6661889091948 5.37946844949662 1.11784793865654e-07 -675.595762557067 116.28930977548 -5.8096119399233 1.07472350823946e-08 HDAC11 other 3.04677043895753e-13 0.000146742747815015 0.00113808098634622 5.37946844949662 -5.8096119399233 0.4944070382013 -1.32813874970431 2.07526327714612 -0.639985665592632 0.522451853321663 6.283641212017 7.00606485645131 0.896885961058568 0.370177231269254 TRAT1 other 1 1 1 -0.639985665592632 0.896885961058568 0.126851825830565 359.8783789577 254.892211114994 1.41188456635633 0.158563135179025 1137.81058831376 646.848164026104 1.75900721620946 0.0791457683222408 FBLN2 other 1 1 1 1.41188456635633 1.75900721620946 2.616049412517e-08 14.1548880720632 15.9184451215092 0.889212983053032 0.374284569174956 -195.578424577695 35.6697296701992 -5.48303635564398 6.42869723150022e-08 GLB1L other 0.000197433249162658 0.00085604532334657 1 0.889212983053032 -5.48303635564398 9.4938474594497e-12 712.608077169604 156.282866964264 4.55973256065587 6.34211346816875e-06 -1187.4598985537 322.935262638373 -3.67708341558052 0.000259512455815192 STT3B other 8.61471718470466e-08 1 0.0579859434394669 4.55973256065587 -3.67708341558052 3.42847655152846e-29 91.2929468038623 7.90143160626981 11.5539754506539 9.77215880732631e-28 -19.9133410410335 19.9353109598865 -0.998897939495544 0.318293189601666 CHCHD4 essential 4.65792824290656e-25 1 1.42126277693754e-23 11.5539754506539 -0.998897939495544 0.23870469326558 41.4934289908934 34.6667955325438 1.19692138697795 0.231862391815366 350.754690275306 309.603226274607 1.13291678027993 0.257751964471198 NFASC other 1 1 1 1.19692138697795 1.13291678027993 0.0240722787417412 -2.0784537505153 0.832570740631219 -2.49642901087241 0.0128420473281173 9.00517288125976 7.79239934848628 1.15563544404447 0.248341363438629 FCRL1 other 1 1 1 -2.49642901087241 1.15563544404447 3.38409842372661e-05 70.7997911714699 15.6591371391307 4.52130858440136 7.56185859827642e-06 71.6295121303319 38.8111485980833 1.8455911437228 0.0654998371402044 SGO2 other 0.195228638064788 1 0.0687297327997344 4.52130858440136 1.8455911437228 0.0849175487056862 -62.226145946896 72.7832718370708 -0.854951204806957 0.392957310131898 -622.879910538066 301.229989870671 -2.06778850540575 0.0391356091749412 SERPINI1 other 1 1 1 -0.854951204806957 -2.06778850540575 3.13658763134908e-18 101.547681112364 44.2210439149711 2.29636553374049 0.0220355981118545 -680.119082890417 90.5726520867673 -7.50909979139037 2.46608214374166e-13 CLASP2 other 3.5600269615812e-14 3.64585584130767e-09 1 2.29636553374049 -7.50909979139037 3.69628569550757e-13 256.887301808264 34.417768130196 7.46379895513582 3.34714034615345e-13 -131.460278564134 118.668024954265 -1.1077986560811 0.268437443496078 SUCLG1 other 3.55213055338278e-09 1 4.1159784836649e-09 7.46379895513582 -1.1077986560811 1.75595138183659e-09 37.9420491309033 5.87558001192077 6.45758360092518 2.3607457275931e-10 -36.7440594660808 53.9353466308227 -0.681261209232361 0.495996118433133 NUAK2 other 1.4205646679058e-05 1 2.68747293629199e-06 6.45758360092518 -0.681261209232361 1.61993821445004e-12 283.099183926351 37.5022036171607 7.54886797630225 1.90541700339602e-13 -43.6384726686709 161.236847521266 -0.270648262723664 0.786765952766957 PRKCI other 1.51853008222547e-08 1 2.35833462510326e-09 7.54886797630225 -0.270648262723664 0.304692876682674 -9.22957459464521 6.82652949389384 -1.3520156329656 0.17693420757255 51.607254505132 66.8325285308778 0.772187670279279 0.44033984715508 MNDA other 1 1 1 -1.3520156329656 0.772187670279279 0.590936869421422 -0.633282017386072 1.57956223452834 -0.400922485700713 0.68863519439918 14.2551350808645 15.0314933014298 0.948351224658998 0.343373321501498 PYHIN1 other 1 1 1 -0.400922485700713 0.948351224658998 0.626579729773959 24.7712806959595 65.3271588197349 0.37918809180595 0.704696426530916 540.043049840994 609.179714318372 0.886508590400557 0.375735974418078 IFI16 other 1 1 1 0.37918809180595 0.886508590400557 0.254861974550786 4.42330212380465 3.22577515885272 1.37123696041414 0.170868553145733 27.7631046678446 30.2629544414576 0.917395713017747 0.35934334986999 AIM2 other 1 1 1 1.37123696041414 0.917395713017747 1.25789180096998e-09 3.46598574658509 1.1366204604933 3.0493782815425 0.00240603174295327 -11.7327012970461 2.58245791649655 -4.5432303938424 6.84498840142537e-06 EFHB other 1.02404971516966e-05 0.0834951685205867 1 3.0493782815425 -4.5432303938424 1.02578907255619e-05 24.1423657557806 4.98819521372936 4.83989994804772 1.70463609395137e-06 -0.603335475913377 21.4508212407977 -0.0281264511573049 0.977571845019407 EIF5A2 other 0.0623269440485143 1 0.0161752918955045 4.83989994804772 -0.0281264511573049 7.21556684319955e-08 174.055547649735 29.8831274821061 5.82454255345124 9.92056693283295e-09 36.3600294367578 128.506924502535 0.282942180567401 0.777331217263586 RPL22L1 other 0.000527385780569455 1 0.000106189748449044 5.82454255345124 0.282942180567401 0.00583145633673666 54.8175528231989 18.1116677478187 3.02664302296518 0.00259146044156221 84.1557120808897 68.2207617810781 1.23357919031962 0.217899405120169 PPM1L other 1 1 1 3.02664302296518 1.23357919031962 0.617163606163847 -3.88323875715084 9.63429131157509 -0.403064286885879 0.687060168739201 -23.0643390956018 23.6699786947135 -0.974413175148022 0.330286912652333 ICA1L other 1 1 1 -0.403064286885879 -0.974413175148022 5.79306176881931e-37 724.640989556206 51.8546532675828 13.9744640816877 4.032228137583e-38 447.106391305128 165.254964599502 2.70555497312106 0.00703370854155714 SNHG16 other 8.35938813240627e-33 1 6.06812139419263e-34 13.9744640816877 2.70555497312106 0.012094372227727 5.3823978025539 3.53880300019328 1.52096564919266 0.128852685961407 25.2198619032789 8.72282304094142 2.89124997548466 0.00399134541052579 CTLA4 other 1 1 1 1.52096564919266 2.89124997548466 0.0127196107799415 3.9976827562185 3.57651437617076 1.11775945396833 0.264164941670183 26.0178650067135 8.81600690684678 2.95120742095917 0.00330230756603454 ICOS other 1 1 1 1.11775945396833 2.95120742095917 1.44956726916204e-21 129.843656730499 49.3031713598122 2.63357616050509 0.00869038946914245 -754.44563839522 96.6730487362834 -7.80409481502222 3.10655946301122e-14 RYBP other 1.77021154910069e-17 4.63219081529604e-10 1 2.63357616050509 -7.80409481502222 8.39211078122252e-24 198.244477723183 37.1371642466949 5.33816950605824 1.37997946939909e-07 -460.513148806133 74.3373324922504 -6.19491086600586 1.15009795025858e-09 PPP4R2 essential 1.06487493702933e-19 1.60898703241176e-05 0.0013969532168727 5.33816950605824 -6.19491086600586 0.786992662808017 -1.16943226097922 1.69580779761378 -0.689601889214546 0.490738088447476 -0.236128301300755 5.73860432749207 -0.0411473396361428 0.967193504241947 CD200R1 other 1 1 1 -0.689601889214546 -0.0411473396361428 4.04820523686076e-13 37.4709935396856 5.26389699598778 7.11848912853852 3.45871070192086e-12 -34.3406737688361 17.6974795358025 -1.94042737551209 0.05284314579337 GTPBP8 other 3.88182400162579e-09 1 4.15425742407715e-08 7.11848912853852 -1.94042737551209 7.43244978886991e-17 143.309938117791 18.6175987968377 7.69755217531773 6.5764694774645e-14 -209.297251980998 62.9877949070861 -3.32282233867266 0.000951023551252868 NEPRO other 8.12961357906591e-13 1 8.22387508156936e-10 7.69755217531773 -3.32282233867266 1.10153384381436e-07 59.2428017010993 19.3816914906905 3.05663732856109 0.00234826605722566 -285.667141259922 65.5622196291887 -4.35719142633696 1.57521495233652e-05 SPICE1 other 0.000794536361543298 0.188001904561363 1 3.05663732856109 -4.35719142633696 1.46567447028888e-07 25.7022171497265 11.0022275371411 2.33609212888586 0.0198520996097545 -171.671843951586 36.2423395639943 -4.73677599230202 2.7805817902299e-06 CCDC191 other 0.00104839694859764 0.0346015597976208 1 2.33609212888586 -4.73677599230202 0.0380747291871252 -6.49218304554952 4.25963435983406 -1.52411744697318 0.128072468278691 -20.7719784318342 8.18801450920412 -2.53687611428687 0.011468723195951 CADPS other 1 1 1 -1.52411744697318 -2.53687611428687 0.328983469365694 15.0513711049002 17.5661178190607 0.85684106527899 0.391912808425144 -34.7810103424244 42.6436651988691 -0.815619627914787 0.415077323095237 NKX6-1 other 1 1 1 0.85684106527899 -0.815619627914787 7.36478557203691e-23 207.627711330218 44.7758320224002 4.63704864772468 4.43617811713395e-06 -775.055939687831 109.018887420657 -7.10937304558268 3.70382203980449e-12 CDS1 other 9.20892787927496e-19 5.4068394137066e-08 0.0409592325554978 4.63704864772468 -7.10937304558268 2.04218469545156e-15 236.302204341263 56.3836100286899 4.19097330272086 3.24488370999464e-05 -720.573131748097 136.959676131004 -5.261206452174 2.06710606691016e-07 WDFY3 other 2.13653362838142e-11 0.00269633315367761 0.280714889751636 4.19097330272086 -5.261206452174 1.25891686515285e-34 91.3451564909667 10.5246187197308 8.67918913962356 4.71520535285194e-17 -217.230763543749 32.0666900270964 -6.77434320037983 3.27524703364969e-11 COX18 other 1.79131280742598e-30 4.71930345078584e-07 6.25424838002281e-13 8.67918913962356 -6.77434320037983 1.244835490999e-10 37.4363023761338 74.0804382846872 0.505346664287651 0.613520048340494 -1121.60210103988 181.641320741324 -6.17481802302657 1.29697214374815e-09 PTPN13 other 1.06781988417894e-06 1.81251857088803e-05 1 0.505346664287651 -6.17481802302657 0.374003415340806 -802.609754606855 1147.50170858785 -0.699441010501478 0.484579317364395 3224.66187849525 3513.06432575548 0.917905731145925 0.359080295362427 ALB other 1 1 1 -0.699441010501478 0.917905731145925 3.77799825668696e-18 151.03229188411 25.9777494886584 5.81390978267959 1.05215131374603e-08 -190.877088263275 50.2241614477809 -3.80050323909806 0.000161063277421412 THOC7 essential 4.27971642517499e-14 1 0.000112517061492 5.81390978267959 -3.80050323909806 1.13142903120507e-14 52.0809437187065 22.8851590481568 2.27575187959645 0.0232568469740589 -266.394701566413 44.245092258457 -6.02088701748599 3.23202088521129e-09 ATXN7 other 1.15303932570109e-10 4.47505611766355e-05 1 2.27575187959645 -6.02088701748599 5.15384079187744e-34 157.437643755482 27.0292683856174 5.82470977421115 9.90142821396147e-09 -418.585723115924 52.1732939916995 -8.02298822042018 6.60589367288714e-15 PSMD6 essential 7.29886932945684e-30 9.91280404553444e-11 0.000105994789030457 5.82470977421115 -8.02298822042018 1.86050148249686e-11 -56.8849434872305 40.7094585937244 -1.39733972035677 0.162891733290294 -542.797858616383 78.4171541850234 -6.92192753304544 1.28221564916228e-11 PRICKLE2 other 1.66366042564869e-07 1.85946913441515e-07 1 -1.39733972035677 -6.92192753304544 0.232845063248055 16.3689572013859 29.7294202241289 0.550597928852328 0.582139583601581 96.8882068938826 57.2667043502822 1.69187677190656 0.0912528617604408 ADAMTS9 other 1 1 1 0.550597928852328 1.69187677190656 0.00235536421183649 152.840927158874 55.2829075275997 2.76470493312185 0.00588931254858001 -143.904841229899 136.198537726396 -1.0565813967767 0.291168231035384 PPM1K other 1 1 1 2.76470493312185 -1.0565813967767 7.5253021569166e-23 650.331621762456 61.4507324769569 10.5829759149953 6.40454337128921e-24 164.816136676939 235.992945921795 0.698394335615255 0.485230152016389 GMPS essential 9.40813275657713e-19 1 9.11238430867029e-20 10.5829759149953 0.698394335615255 0.228156830072743 7.81548458118229 40.8755652337002 0.191201871741672 0.84843930434315 -267.144680264163 156.932390509067 -1.70229153712361 0.0892762525407562 TIPARP other 1 1 1 0.191201871741672 -1.70229153712361 0.00326076972728795 129.563631871563 38.142674817513 3.39681557445664 0.000732063694333086 48.2576193594266 147.909455728675 0.32626459966123 0.744350808509737 CCNL1 essential 1 1 1 3.39681557445664 0.32626459966123 1.15775491095555e-05 93.5561050738453 34.8965805755628 2.68095336364733 0.00756654422446586 557.352941843423 136.413757441289 4.08575316960462 5.06294040670875e-05 PTX3 other 0.0700325945637015 0.583858287701653 1 2.68095336364733 4.08575316960462 0.0124778216162424 0.977313563486725 1.09245463140905 0.894603341308721 0.37139407022292 -4.20196040387211 2.03716075624506 -2.06265528677141 0.0396186347283021 HESX1 other 1 1 1 0.894603341308721 -2.06265528677141 0.844837020123183 -0.145081134366032 1.26246160770199 -0.114919244657362 0.908551534767451 1.18052961840104 2.48633136364583 0.474807837628678 0.635114499543809 DCLK3 other 1 1 1 -0.114919244657362 0.474807837628678 1.24365543854596e-24 175.487702990456 51.9400231761792 3.37866046757827 0.000780869271349448 -746.050360041443 97.7679377903786 -7.63082843826601 1.05955310880545e-13 SLMAP other 1.59847033516312e-20 1.57290659002168e-09 1 3.37866046757827 -7.63082843826601 1.2523412059583e-06 164.763363034599 95.2598300707412 1.72962058521671 0.0842622051103983 -667.735775324629 192.773087478297 -3.46384334068314 0.000574236722970469 RPL9 essential 0.00828674175982605 1 1 1.72962058521671 -3.46384334068314 6.34371259285345e-36 371.135016470574 255.141886081129 1.45462206214374 0.146347490832302 -5760.32712700464 516.850000726895 -11.1450655294638 3.88146010571607e-26 SMIM14 other 9.10830254081899e-32 6.05352518087478e-22 1 1.45462206214374 -11.1450655294638 2.04090377710705e-27 56.8783345053441 15.0168085551861 3.78764464475383 0.000169001518350658 -225.296365173116 28.3983342098115 -7.93343593707256 1.21760099624328e-14 RPP14 essential 2.72174927714996e-23 1.82238341107732e-10 1 3.78764464475383 -7.93343593707256 1.58740932524481e-07 37.8153988789162 10.5028389731178 3.600493064371 0.000346665055695943 -42.4271368102891 19.8235835583636 -2.14023547686911 0.0327798021399328 ABHD6 other 0.00113229907169712 1 1 3.600493064371 -2.14023547686911 0.638951539537293 2.13629157066589 4.54774291506682 0.4697476551694 0.638723553080293 -4.27882777896037 8.58363742503623 -0.4984865467966 0.618342631535449 DNASE1L3 other 1 1 1 0.4697476551694 -0.4984865467966 0.0170087276368939 35.0874943660356 13.5948786993496 2.58093471387239 0.0101135872701888 3.48967447099649 25.7677410386868 0.135428032506118 0.892323465186366 C3orf67 other 1 1 1 2.58093471387239 0.135428032506118 1.33837107177676e-27 130.375485849964 127.119129008491 1.02561657609576 0.305526511443258 -2527.36279405337 261.450730097308 -9.6666886074968 1.64285164615422e-20 RBM47 other 1.78806375189376e-23 2.53393437902828e-16 1 1.02561657609576 -9.6666886074968 2.14883609915359e-13 229.432605209457 152.470546353782 1.50476672836928 0.132962292110125 -1900.90679180368 316.825981583504 -5.99984503260402 3.59893849988498e-09 APBB2 other 2.08673473588805e-09 4.97841162689089e-05 1 1.50476672836928 -5.99984503260402 5.68269984161118e-08 138.789784497469 23.6634587561232 5.8651520865079 7.81770375758049e-09 59.4739709806617 72.1781454039469 0.82398862769075 0.410309128611833 IL17RE other 0.000419326421312489 1 8.40168622827175e-05 5.8651520865079 0.82398862769075 6.48010493409555e-26 426.883629512633 37.7742603542186 11.3009129896824 1.01902727400323e-26 2.05324406210162 115.247826860338 0.017815902633807 0.985792323314432 IL17RC other 8.48699343218495e-22 1 1.47402295184567e-22 11.3009129896824 0.017815902633807 3.70603638543903e-24 198.411643083926 19.6439654017275 10.1003865068138 4.83472680969427e-22 -182.508410499135 60.5502282384891 -3.01416552519488 0.0027011572009078 CRELD1 other 4.72890242782021e-20 1 6.76668364284811e-18 10.1003865068138 -3.01416552519488 7.73774829715443e-21 174.058354089088 21.0425485943078 8.27173349791728 1.09695137538249e-15 -299.455821458895 65.2054620774679 -4.5924959645731 5.49083680975781e-06 PRRT3 other 9.32243914841166e-17 0.0673231501244405 1.41901629919479e-11 8.27173349791728 -4.5924959645731 9.54529494739946e-43 23.1787810256119 1.53798979269597 15.0708289064659 3.51627928038065e-43 19.3804381235319 4.68648580992141 4.13538820121956 4.10069412808457e-05 FANCD2OS other 1.4142308994067e-38 0.475434477210125 5.34439287825055e-39 15.0708289064659 4.13538820121956 0.101750275681184 83.8173175088837 51.343765911097 1.63247311570436 0.103156396687471 289.21714317172 180.906185614957 1.59871340047649 0.110462788234986 PCOLCE2 other 1 1 1 1.63247311570436 1.59871340047649 1.37629597251427e-15 419.043773996225 50.1927253356955 8.34869537753939 5.7205570995418e-16 -122.369960129549 178.503842042162 -0.685531239717775 0.493300239551986 U2SURP essential 1.44868914066852e-11 1 7.44358889792379e-12 8.34869537753939 -0.685531239717775 2.9922096811672e-62 314.395042699569 16.4721242712672 19.0864904563632 1.8814196031503e-62 -9.34266863293265 49.6565968852571 -0.188145568141148 0.850833220896612 MTMR14 other 4.60830212996561e-58 1 2.91036798411319e-58 19.0864904563632 -0.188145568141148 0.00296752000144276 -40.363502703668 27.2085971972728 -1.48348341559166 0.138535975647168 -319.867882554132 104.283046562223 -3.06730473551399 0.00226947965629522 TTC14 other 1 1 1 -1.48348341559166 -3.06730473551399 0.000242014998215753 30.4310727016749 15.5035702630995 1.96284289265323 0.0501802278680135 194.566680645838 47.9328782491596 4.05914870445421 5.65774232281916e-05 CXCL5 other 1 0.649904860622237 1 1.96284289265323 4.05914870445421 3.55334704712839e-14 44.3928906481358 7.76081965718577 5.72012913700839 1.76627928748352e-08 -83.6040935740263 23.8969035090665 -3.49853249992439 0.000506487796294734 MTHFD2L other 3.55725572888023e-10 1 0.000187190278887503 5.72012913700839 -3.49853249992439 4.64117008530595e-06 5.26696597070375 7.23704851586968 0.727778176304075 0.467066581782872 110.142297913609 22.3750116590945 4.92255823557708 1.13829591033201e-06 CXCL1 other 0.0290722894143565 0.0144187942961756 1 0.727778176304075 4.92255823557708 1.96029296089551e-20 81.970532700018 12.9127579805309 6.34802672082975 4.63851430235991e-10 -192.53784064696 37.9828852599038 -5.06906832720816 5.5072561675068e-07 RCHY1 other 2.34078582460533e-16 0.0070744075181608 5.23038872734103e-06 6.34802672082975 -5.06906832720816 1.26782784496701e-06 -9.82660902551772 2.93149303744253 -3.35208335820937 0.00085844113922965 -40.9759518255314 8.22007311349271 -4.98486464290348 8.374959571004e-07 CCDC158 other 0.00838414553876682 0.0106747234692017 1 -3.35208335820937 -4.98486464290348 0.065910097992802 -88.714349833334 44.9753019443488 -1.97251260131854 0.0490580272923226 -240.692599077812 175.3018644635 -1.37301790722213 0.170313500376626 CPA3 other 1 1 1 -1.97251260131854 -1.37301790722213 7.22509554177126e-13 204.88264446985 29.1555509451794 7.02722595964956 6.34258242259456e-12 -301.145521561117 113.640647626441 -2.64998068781728 0.00828429719422162 GYG1 other 6.85806068824928e-09 1 7.56226102245949e-08 7.02722595964956 -2.64998068781728 0.046580153022268 321.251139329971 130.981491993313 2.4526452893541 0.0144945262409851 280.685736202478 517.888815950338 0.541980686892057 0.588054140367549 HPS3 other 1 1 1 2.4526452893541 0.541980686892057 0.832503726287202 16.7512744682055 32.7118048648766 0.512086524647612 0.608798661712318 -37.6234045370656 129.339478664164 -0.290888790689783 0.771247445939998 TM4SF18 other 1 1 1 0.512086524647612 -0.290888790689783 4.004521886606e-16 341.010171879731 39.5251294231806 8.62768008242717 6.86858939076529e-17 46.5955527866421 136.817228877272 0.340567874155961 0.733560153078691 TOPBP1 essential 4.2860397752344e-12 1 9.0837094692871e-13 8.62768008242717 0.340567874155961 1.3315977688095e-16 254.86649599664 31.4704560474375 8.09859557206491 3.65958667142404e-15 -236.040066689041 110.196975934439 -2.14198315958752 0.0326373840649232 RYK other 1.44531621826583e-12 1 4.69268798876705e-11 8.09859557206491 -2.14198315958752 3.50977358673597e-15 18.6943064823086 32.8731699016996 0.568679763412231 0.569806880080076 -447.625030382244 62.7866088242324 -7.12930732786262 3.20610805378053e-12 SNRK other 3.64525084718398e-11 4.68444447737874e-08 1 0.568679763412231 -7.12930732786262 0.00243275862967115 -1.00422488721184 1.8024991432846 -0.557129189743688 0.577670005455597 -19.1197692009737 5.49726149287028 -3.47805343183533 0.000545799676298319 UCN other 1 1 1 -0.557129189743688 -3.47805343183533 2.13916523775693e-05 24.3059126587055 12.1313488620343 2.00356225306257 0.045618873708602 -134.336668732537 36.9109805688561 -3.63947710578798 0.000299596376371992 ZNF513 other 0.126018224156261 1 1 2.00356225306257 -3.63947710578798 5.10669391262597e-17 122.823933452656 14.1186511915939 8.69940986471742 3.99971741136153e-17 -9.29669828236398 43.596609284693 -0.213243608503015 0.831217140435166 SLC4A1AP other 5.61225660997594e-13 1 5.30962486358244e-13 8.69940986471742 -0.213243608503015 0.253037399111528 5.64866076104141 3.71658166215204 1.51985379967963 0.129127629386969 -3.66757353818717 11.3703212287807 -0.322556721520212 0.747154675717416 PLB1 other 1 1 1 1.51985379967963 -0.322556721520212 1.30686948288814e-11 251.586327808743 34.7921720886111 7.23111874613594 1.62685075290726e-12 120.832811784407 106.466957696792 1.13493251238123 0.256901578267634 SPDYA other 1.17735871713393e-07 1 1.9699535766954e-08 7.23111874613594 1.13493251238123 2.33891197443229e-32 88.0687173422083 26.3568613879076 3.34139623250489 0.000890928432937549 -471.624794342829 50.4167411546431 -9.35452755457193 2.19108507734385e-19 KIAA1143 other 3.26909726666402e-28 3.36638311283109e-15 1 3.34139623250489 -9.35452755457193 7.13373519764668e-07 93.0044056995973 20.3734466843314 4.56498142609931 6.18171932734602e-06 183.475275163485 38.985602078878 4.70623166963708 3.20502355616921e-06 KIF15 other 0.00482668523472774 0.0397487021436106 0.0565750952838707 4.56498142609931 4.70623166963708 0.628377951328801 -24.0033696123781 61.6952009503309 -0.389063804682353 0.697380078861246 -112.911075176835 117.518673059764 -0.96079263181787 0.337080174701121 TGM4 other 1 1 1 -0.389063804682353 -0.96079263181787 1.60094124061802e-16 290.129342086724 33.6937757341655 8.61076966783906 7.7904866547895e-17 -0.0272201314451461 104.809534624175 -0.000259710450416097 0.999792875902371 WDR43 essential 1.73253861059682e-12 1 1.02927909683079e-12 8.61076966783906 -0.000259710450416097 5.93590720907151e-22 156.299073048578 37.9361124198703 4.12006036144894 4.37328320464237e-05 -458.137668388215 72.2617241528783 -6.33997699001715 4.80641609282253e-10 ZDHHC3 other 7.30828895580884e-18 6.77993054053545e-06 0.373522118508505 4.12006036144894 -6.33997699001715 0.419325490333992 55.132715763644 74.4856715811382 0.740178810143199 0.459508492897684 -85.2652941692149 141.649915241019 -0.601943841788645 0.547460476390997 CDCP1 other 1 1 1 0.740178810143199 -0.601943841788645 0.639174601458342 70.4692365781779 76.8134463429438 0.91740756251918 0.359332682852704 34.6431805675886 146.316312262887 0.23676909315036 0.812924408149111 CLEC3B other 1 1 1 0.91740756251918 0.23676909315036 0.536565296260542 -0.751467976796505 6.10471488789111 -0.123096326461874 0.902076034778405 10.4622291937966 11.3794680195234 0.919395280679803 0.358294104385718 SLC6A20 other 1 1 1 -0.123096326461874 0.919395280679803 2.40828811630818e-43 18.2848771533458 27.4061845877242 0.667180690359065 0.504938068484546 -673.771225196972 51.0916918713727 -13.1874909700239 1.11725612019842e-34 LZTFL1 other 3.57582619509438e-39 1.75040516351486e-30 1 0.667180690359065 -13.1874909700239 5.53803823789239e-14 24.0043777888845 75.3082067726392 0.318748497907477 0.750038908548637 -969.116122716374 140.408548056068 -6.90211626096571 1.4237371387572e-11 FYCO1 other 5.50037957787472e-10 2.06327986148694e-07 1 0.318748497907477 -6.90211626096571 0.0170796861529889 23.620071474776 20.8629781717792 1.13215243194408 0.258066404218645 111.074087186852 38.9602621392114 2.85095841475516 0.00452330662761604 CCR1 other 1 1 1 1.13215243194408 2.85095841475516 0.352052647951355 10.1849293434591 20.1121965823414 0.506405618190978 0.612779388249851 53.8286495633399 37.5911888226582 1.43194858287894 0.152739236961566 LRRC2 other 1 1 1 0.506405618190978 1.43194858287894 2.65230633022791e-26 51.4532457456526 13.476117746951 3.81810597917148 0.000150659321635652 -187.522387772183 24.9700114102646 -7.50990396804932 2.58729162077976e-13 ELP6 essential 3.48857851614877e-22 3.82375828635041e-09 1 3.81810597917148 -7.50990396804932 4.18964965623079e-10 491.484252288502 83.1093782103818 5.91370387881336 5.91395373297695e-09 -562.029565210743 272.993215529645 -2.05876751962618 0.039992078330994 DTX3L other 3.50254711260894e-06 1 6.388844217735e-05 5.91370387881336 -2.05876751962618 1.26100412681546e-10 156.881817103832 36.735902471921 4.27053118468356 2.30012900006192e-05 -512.273382691872 116.727796112956 -4.38861522062966 1.36978072224331e-05 ZNF148 other 1.08131103874426e-06 0.164072334910304 0.201284288795419 4.27053118468356 -4.38861522062966 0.0032502201846687 -21.4570567383943 14.2177070962087 -1.50917842048638 0.131832687471118 -170.338618928169 53.2249731272751 -3.20035143128854 0.00145251088609121 NMNAT3 other 1 1 1 -1.50917842048638 -3.20035143128854 4.69483027746328e-14 63.191009546184 18.6788095845158 3.38303194645592 0.000768898533324915 -178.437481238789 33.7887683617089 -5.28097027179608 1.8658843037606e-07 SMIM12 other 4.6727645751592e-10 0.00243852419658473 1 3.38303194645592 -5.28097027179608 8.44849538545417e-13 32.9948048145427 14.8990020722122 2.21456475102319 0.0272067074158928 -155.255578633107 27.0438288661392 -5.74088748311441 1.57241720166399e-08 ZMYM6 other 8.0007251300251e-09 0.000213691497706137 1 2.21456475102319 -5.74088748311441 6.73301000135446e-10 109.207876587828 18.9571828296945 5.76076506561748 1.41012755617892e-08 -119.677491119136 60.2802225497414 -1.98535250961261 0.0476125428979448 TPRA1 other 5.56011965911851e-06 1 0.000150122179630808 5.76076506561748 -1.98535250961261 1.90448581800874e-26 377.837853778453 34.5680210625244 10.9302714521912 2.84525203952733e-25 455.626506532104 149.556942650968 3.04650856360064 0.00242766035059687 YEATS2 essential 2.50935051380832e-22 1 4.08151405070196e-21 10.9302714521912 3.04650856360064 0.143657871966031 -138.128769877875 72.0095979158972 -1.9181994327923 0.0556098310078994 -161.708428772497 150.528591841332 -1.07427052093166 0.283178589260786 GRIK3 other 1 1 1 -1.9181994327923 -1.07427052093166 4.4796388878025e-07 246.835038511849 71.8087178869866 3.43739654146619 0.000632524881136767 -427.890241082531 147.574367393062 -2.89948890611099 0.00388951932654802 MEAF6 other 0.00308199155480812 1 1 3.43739654146619 -2.89948890611099 1.62041167273344e-14 50.8460979508796 12.2512732885386 4.15027048645202 3.85678179691476e-05 -133.974105830871 25.1776380154984 -5.32115465908284 1.51258792330594e-07 SNIP1 essential 1.64212518914807e-10 0.00198648171967769 0.331027581629193 4.15027048645202 -5.32115465908284 0.0126928391462078 -70.7328665984334 69.3180752067022 -1.02041013671416 0.307990073425913 -423.385720090481 142.718872715582 -2.96657135832502 0.00314448333725142 DNALI1 other 1 1 1 -1.02041013671416 -2.96657135832502 1.48933914680913e-21 254.06005479351 24.9208349015249 10.1946847205333 2.15543164263967e-22 -175.810661401345 110.814490820044 -1.58653132907366 0.113219768633387 POLR2H essential 1.81833416433927e-17 1 3.02644156943037e-18 10.1946847205333 -1.58653132907366 0.863399721674687 2.19619087338825 7.63862805772391 0.287511167815998 0.773830643188577 -9.66399151210437 24.6303015823959 -0.392361883177734 0.694944806350481 KLF15 other 1 1 1 0.287511167815998 -0.392361883177734 0.0813885262458781 9.91485079862325 5.53937724717792 1.78988546116343 0.0740388055454466 -35.1038217160921 24.3566714219053 -1.44124051714724 0.150102870848056 CAMK2N2 other 1 1 1 1.78988546116343 -1.44124051714724 0.00404261158756554 45.2307403439542 21.2012302375307 2.13340168646847 0.0333402258523344 -218.19507555486 86.0477834599415 -2.53574312761279 0.0115006902237895 LIPH other 1 1 1 2.13340168646847 -2.53574312761279 5.14119077541635e-28 178.882181181952 15.1970364916129 11.7708594883401 1.23253901782553e-28 -95.4701998008402 61.6201835866226 -1.5493332580977 0.121886389067592 TMEM41A other 6.89947802060875e-24 1 1.80061625114132e-24 11.7708594883401 -1.5493332580977 1.9571615990461e-22 1847.75558298053 188.922513756247 9.78049437434736 6.58163873077328e-21 -1125.6392716794 623.839067730426 -1.80437444511861 0.0717296683376648 RPN1 essential 2.43079470601525e-18 1 9.12807475570946e-17 9.78049437434736 -1.80437444511861 3.97450349478737e-10 134.753634371746 22.2030438089087 6.06915139795731 2.41761219788019e-09 -250.911152010458 90.1137662492122 -2.78438203677512 0.00555039792570109 SENP2 other 3.32626197478755e-06 1 2.64801064033818e-05 6.06915139795731 -2.78438203677512 0.000366765542911211 -79.5894286654234 19.8717040995197 -4.00516373768604 7.06431140596431e-05 -58.6305790108567 43.5088665007987 -1.34755473369504 0.178365696487137 HEYL other 1 1 0.591565437135452 -4.00516373768604 -1.34755473369504 1.02628858028498e-08 256.701505048536 52.3105603381329 4.90725970796776 1.22472628692652e-06 -462.804925820463 168.36592683533 -2.74880395647457 0.0061815181534412 IFT122 other 7.92500041696063e-05 1 0.0117292036498952 4.90725970796776 -2.74880395647457 2.31777911446894e-32 222.113229330929 17.6584909360554 12.5782678789055 5.14637550481977e-32 232.495896222874 72.9483715835609 3.1871293515655 0.00151974954806341 RFC4 essential 3.23979164620468e-28 1 7.61817965978471e-28 12.5782678789055 3.1871293515655 5.04674412531e-09 119.77336853304 19.0356857406087 6.29204380473295 6.48198282452707e-10 12.1027359352462 78.5679484276463 0.154041643920379 0.877634451515732 RPL39L other 3.97532034750669e-05 1 7.26500634972993e-06 6.29204380473295 0.154041643920379 1.01129899559219e-42 143.634122244436 35.9476312929854 3.99564914510691 7.36503948582179e-05 -715.28066718018 65.7445165339059 -10.8797007703493 5.07829535904399e-25 BAP1 other 1.49803720217071e-38 7.90589021495968e-21 0.616011902594134 3.99564914510691 -10.8797007703493 8.49308048877108e-07 1143.45237933083 220.531028212249 5.18499545664984 3.06850400863169e-07 530.686728777117 403.887877765422 1.31394567153942 0.18942760050152 TKT essential 0.0057132952447963 1 0.00305039983498076 5.18499545664984 1.31394567153942 1.31120304647662e-21 516.721289643969 95.8751326187713 5.3895235973087 1.06011859399269e-07 -885.389084344289 175.539681465006 -5.04381161544258 6.25610685134547e-07 PRKCD other 1.60215900248979e-17 0.00801594970862895 0.00108047287099735 5.3895235973087 -5.04381161544258 8.06641021582967e-39 81.3374561825362 12.9183724380956 6.2962618992681 6.35274477259832e-10 -196.399862124707 23.6525042614191 -8.30355466609367 8.28356907819636e-16 RFT1 essential 1.17487264793559e-34 1.25115027357078e-11 7.12460326246901e-06 6.2962618992681 -8.30355466609367 9.29555106874781e-20 64.039904552635 19.6353673085992 3.26145691833272 0.00117890029133348 -232.326705910914 35.9233036393599 -6.46729789228966 2.24955043917684e-10 SFMBT1 other 1.09603842651605e-15 3.19593630893854e-06 1 3.26145691833272 -6.46729789228966 8.49894577051451e-28 332.09228673832 58.5436900512154 5.67255474412013 2.30584195489387e-08 -670.796426984986 106.347813080325 -6.30757142583019 5.94326791416809e-10 GNL3 essential 1.13775387029878e-23 8.37049853031434e-06 0.000243151034143559 5.67255474412013 -6.30757142583019 5.13645997515123e-15 167.200729728783 63.2782674276087 2.64230890834778 0.00847770168176421 -641.814654228838 114.656259141734 -5.59772889010317 3.48877207730159e-08 PBRM1 other 5.30339492434364e-11 0.000468542089981604 1 2.64230890834778 -5.59772889010317 9.87379893712472e-24 67.5492683036482 10.1889164370999 6.62968125419965 8.20898137355347e-11 -139.444367626993 26.4115158771188 -5.27968058614152 1.88220072322509e-07 UVSSA other 1.25160275326993e-19 0.00245909524489358 9.4789107920422e-07 6.62968125419965 -5.27968058614152 1.1056599543922e-27 146.548793868372 56.787819475564 2.58063780616602 0.0101217017606637 -935.952526850109 105.64259296647 -8.85961334882393 1.12916288935154e-17 FAM208A other 1.47870962300413e-23 1.7242317320398e-13 1 2.58063780616602 -8.85961334882393 3.48020500310775e-15 -124.716246089084 54.3855733891805 -2.29318619473992 0.0222164466915765 -831.402406481091 101.399404635153 -8.19928291958495 1.73664424772802e-15 ARHGEF3 other 3.61488893672802e-11 2.6172965457509e-11 1 -2.29318619473992 -8.19928291958495 3.46756111749421e-30 384.619879472205 31.389123635789 12.2532850529689 1.30355449755216e-30 236.399861971595 81.3662907526457 2.9053783794846 0.0038193164162733 SLBP essential 4.75194575541406e-26 1 1.9207875521431e-26 12.2532850529689 2.9053783794846 5.49861720710021e-17 393.847003288009 98.194549517207 4.01088456767138 6.89521461755031e-05 -944.764485077482 190.840456149864 -4.95054614801158 9.88729379263773e-07 LRPAP1 other 6.03638196995461e-13 0.0125618067635462 0.578301649973944 4.01088456767138 -4.95054614801158 3.3602973834693e-07 19.566715629671 3.57287129177927 5.47646809295692 6.66387969419615e-08 -14.3254625080995 16.7740848604822 -0.854023490834282 0.393471366496986 SLC51A other 0.0023370868302029 1 0.000687912300831868 5.47646809295692 -0.854023490834282 8.87059451314326e-26 317.014712184627 28.0228520743293 11.312721179977 9.14061196112181e-27 -115.103101593951 133.464532755913 -0.862424639843887 0.388838141887677 UBXN7 other 1.15898606932785e-21 1 1.32264655077433e-22 11.312721179977 -0.862424639843887 8.73276753824288e-41 231.264594635183 15.5961990511503 14.8282664177799 5.90758324823478e-42 28.3665294341384 74.2800701944544 0.381886142001199 0.702696609806709 RNF168 essential 1.28310553439403e-36 1 8.96003151259769e-38 14.8282664177799 0.381886142001199 6.14174768055988e-25 215.061662561888 20.8378096681646 10.3207422462665 6.70454568707329e-23 -367.897717057224 92.67690058894 -3.96968084516552 8.17789293017649e-05 PIGX other 7.93022460513892e-21 0.927618395069919 9.46078441902912e-19 10.3207422462665 -3.96968084516552 0.000680839871195328 406.359284144979 113.839928336834 3.56956728699466 0.000389811623362537 753.253268286773 503.454673562982 1.4961689856923 0.135200388051563 MELTF other 1 1 1 3.56956728699466 1.4961689856923 0.0415393003736409 724.559320839939 312.51988433709 2.31844230448522 0.020795104288906 153.199383011742 601.246229875687 0.254803066363372 0.798971501319826 S100P other 1 1 1 2.31844230448522 0.254803066363372 0.643314082435562 9.28965358994592 11.8658040141878 0.782892889418906 0.434030061245871 21.2220565386737 26.3236723103123 0.80619665404207 0.420481102440631 ABLIM2 other 1 1 1 0.782892889418906 0.80619665404207 5.01748882198035e-13 54.5163569746139 8.35145261035042 6.52776942145954 1.53858800511133e-10 -33.2567668308318 17.7942249635879 -1.86896405428642 0.0621679273391073 EXO5 other 4.79270532275563e-09 1 1.76199098345349e-06 6.52776942145954 -1.86896405428642 0.0516292253169851 -8.9097712530911 3.91847496183023 -2.27378542414612 0.0233705672650141 -14.4320607049571 9.3648569541016 -1.54108714908199 0.123881345531514 CLDN19 other 1 1 1 -2.27378542414612 -1.54108714908199 1.24990012926133e-21 29.1555134882745 4.33057457125138 6.73248156995703 4.27401849230875e-11 -54.9219268467491 10.3205619497913 -5.32160236176476 1.51009069014971e-07 C1orf50 other 1.52825288804783e-17 0.00198335311244263 4.97196571210276e-07 6.73248156995703 -5.32160236176476 6.39454383365714e-12 37.3485534301729 12.8340895935718 2.9101053999872 0.00376179862166327 -170.965759973379 30.8428877800688 -5.54311779080102 4.6491836500514e-08 ERMAP other 5.85356542532975e-08 0.000622293231559379 1 2.9101053999872 -5.54311779080102 1.75495971996692e-21 55.4506642917384 7.27430890752592 7.62280857146028 1.12074242287567e-13 -72.7570052218902 17.4816212460253 -4.16191405808158 3.67105899693144e-05 ZNF691 other 2.13929589863968e-17 0.426944161343126 1.39386735133047e-09 7.62280857146028 -4.16191405808158 1.93441916617158e-30 310.009844466048 31.5973756732134 9.81125292404768 5.115938370662e-21 -214.476136242528 68.6195373099213 -3.12558412152858 0.00187012542195729 AIMP1 other 2.65653784090343e-26 1 7.10245723999005e-17 9.81125292404768 -3.12558412152858 0.0133729700344444 99.7346592041023 34.406020730096 2.89875600513317 0.00389876486499001 49.8880336964515 74.7551980415983 0.667352037094341 0.504832371025121 SGMS2 other 1 1 1 2.89875600513317 0.667352037094341 3.39363222193296e-17 263.877141513294 32.9863940599015 7.99957525015033 7.56403053079088e-15 -56.5301190508841 73.9258131965553 -0.764687145213822 0.444789441255958 METAP1 essential 3.74928487879153e-13 1 9.64867734507685e-11 7.99957525015033 -0.764687145213822 3.86486248099873e-23 152.146275578462 29.3246971803934 5.18833236853295 2.99966257860969e-07 -425.444464712898 64.93816797762 -6.55153167948196 1.3220675618211e-10 DNAJB14 other 4.85542673487871e-19 1.88553275666926e-06 0.00298376436694306 5.18833236853295 -6.55153167948196 1.15050850600715e-16 1419.94196064235 160.899626468818 8.82501713524817 1.50015001485123e-17 950.799353971814 356.350516344265 2.66815764356368 0.00785473496756994 H2AFZ essential 1.25186830538638e-12 1 2.00315031483085e-13 8.82501713524817 2.66815764356368 0.00108770572919007 -79.7049537324219 25.6574440326323 -3.10650404736534 0.00199207441194505 -176.541775152899 56.9298889613878 -3.10103845929924 0.0020285529056037 EMCN other 1 1 1 -3.10650404736534 -3.10103845929924 3.16733240714831e-33 35.0744792389954 3.17442671423028 11.0490751233172 9.78955028277229e-26 -16.7569683364526 7.30709412943984 -2.29324654091149 0.0222157538827468 SLC9B1 other 4.46023749574625e-29 1 1.40812891267397e-21 11.0490751233172 -2.29324654091149 0.683727913473691 3.74966862185718 53.0118036498814 0.0707327116545972 0.943636576330765 -94.2403083157178 121.797095650684 -0.773748403541581 0.439416936666644 SLC9B2 other 1 1 1 0.0707327116545972 -0.773748403541581 5.62483554692659e-09 -2.40757942337816 16.8429054710231 -0.14294323669513 0.886388135136572 -225.804114405845 38.6973622372537 -5.83512935640002 9.25512025561634e-09 BDH2 other 4.42168322343899e-05 0.000126684086058876 1 -0.14294323669513 -5.83512935640002 3.8443548266568e-18 296.390169184325 104.306511576428 2.84153083738357 0.00466033635575707 -1491.58556287208 215.827634808545 -6.9110036080191 1.36857940613236e-11 PGRMC2 other 4.35373184118883e-14 1.98348213330763e-07 1 2.84153083738357 -6.9110036080191 1.64609452608277e-07 67.636407907024 16.0891927192555 4.20384099359297 3.08853082120306e-05 158.76285345456 29.4800367616387 5.38543607452867 1.09547816969236e-07 CDC25A other 0.00117317156873919 0.00144778394906543 0.267837392814729 4.20384099359297 5.38543607452867 0.889313589068681 9.70273831017308 22.0728474769786 0.439578007336515 0.660424695268076 1.2577988693861 39.852540872904 0.0315613218589354 0.974833952285635 CAMP other 1 1 1 0.439578007336515 0.0315613218589354 7.34407401254452e-27 10.4538428267777 9.55858687323894 1.09365986472804 0.274606682320853 -166.435755467409 17.2430554645796 -9.6523354465395 2.12468292047439e-20 ZNF589 other 9.72869484441773e-23 3.27562365849536e-16 1 1.09365986472804 -9.6523354465395 2.27337853807834e-21 -102.937586587866 105.885570665284 -0.972158774241896 0.331423552424118 -1791.96788207343 190.899636302634 -9.38696331109094 1.91861069173224e-19 PLXNB1 other 2.76601966727991e-17 2.94909649426163e-15 1 -0.972158774241896 -9.38696331109094 1.62535997459034e-29 91.8565636392309 20.9193506494888 4.39098541720154 1.36762591446957e-05 -301.260312222768 37.7078194764571 -7.98933262133761 8.79714647766569e-15 CCDC51 other 2.21276506940729e-25 1.31851631407253e-10 0.121978555311541 4.39098541720154 -7.98933262133761 5.22899728554495e-30 34.7305814909524 18.1914918853438 1.90916620307175 0.056791819954011 -323.904714463943 32.8553185591418 -9.85851693633383 3.94242567870774e-21 ATRIP essential 7.15379118635405e-26 6.09262464387494e-17 1 1.90916620307175 -9.85851693633383 1.33243786893433e-20 574.922725059882 137.00684733168 4.19630650771819 3.19149159993991e-05 -1472.84441003829 247.489951903854 -5.95112811129588 4.90424629542833e-09 SHISA5 other 1.59626056698333e-16 6.76246521676613e-05 0.2761916830588 4.19630650771819 -5.95112811129588 0.000497082117086097 -154.550207579104 63.9447610257773 -2.41693307004153 0.0159835108501176 -521.025106449073 138.049694299372 -3.77418515190036 0.000178380315117256 SPRY1 other 1 1 1 -2.41693307004153 -3.77418515190036 0.00104240622282351 21.7493896194872 13.7902209896516 1.57716033962097 0.115373858119597 -55.025195376765 25.0850867526253 -2.19354215990528 0.0287154379689711 BSN other 1 1 1 1.57716033962097 -2.19354215990528 2.19105113422872e-37 367.429027728638 81.7088218794889 4.49680976027966 8.54044558512402e-06 -1418.26496361075 148.05717073138 -9.57917104997171 4.20095828812591e-20 APEH other 3.16957457077526e-33 6.47157624285797e-16 0.0773935178923939 4.49680976027966 -9.57917104997171 1.07129739921875e-15 1.30477681962316 17.3724832499791 0.0751059477708656 0.940158333833864 -283.086549060417 36.3822269769051 -7.78090217622236 3.70578559851456e-14 INTU other 1.13171857253469e-11 5.52199112034655e-10 1 0.0751059477708656 -7.78090217622236 4.207899722231e-31 137.847792403106 27.6424840369805 4.98680915284934 8.42373054298877e-07 -392.312223049412 50.1479694780408 -7.8230928815812 2.9786661297388e-14 RNF123 other 5.8182629459288e-27 4.44238266589245e-10 0.00814490506201584 4.98680915284934 -7.8230928815812 0.0650103724992083 84.5296498241951 36.1506651224647 2.33825987814722 0.0197391777348359 60.9509746317902 75.5558108422687 0.806701350330715 0.420195027746652 HSPA4L other 1 1 1 2.33825987814722 0.806701350330715 1.55025219966202e-22 56.2731709548576 10.7088083392328 5.25484901515092 2.13900618061152e-07 -137.77251960553 22.3816821760878 -6.15559270843029 1.46326361676516e-09 MFSD8 other 1.92866876159952e-18 2.04227702991914e-05 0.00214456759668111 5.25484901515092 -6.15559270843029 4.77859096788727e-19 24.3165456997939 7.63236303967584 3.18597865083036 0.00152632166803781 -110.389819281339 15.9518331447495 -6.92019646141255 1.2870878481916e-11 ABHD18 other 5.53169690442631e-15 1.86640608866265e-07 1 3.18597865083036 -6.92019646141255 3.14084320633494e-13 16.7197211049446 6.45322518889048 2.59090929195038 0.00983744102689418 -60.624551205261 11.694003007898 -5.18424282637141 3.09624140899994e-07 MON1A other 3.02997144115132e-09 0.00401427698676842 1 2.59090929195038 -5.18424282637141 5.77839721425913e-09 47.5134278552923 30.5764086257667 1.55392441397623 0.120802750372868 -252.953860451666 55.4080485299028 -4.56529091283824 6.21446217576053e-06 MST1R other 4.53719749263627e-05 0.0759469422499694 1 1.55392441397623 -4.56529091283824 8.40224821965607e-09 114.713479901571 24.7109578345731 4.64221098467806 4.38775492259483e-06 -61.6268894877651 45.3349179680348 -1.35936916288715 0.174629210228782 RAD54L2 other 6.52938709149473e-05 1 0.0405296922200084 4.64221098467806 -1.35936916288715 4.44505307747789e-24 158.567421621662 62.9507922147763 2.51891066089621 0.0120759636008486 -936.588043101831 115.466192052486 -8.11136165879707 3.74365744738572e-15 TEX264 other 5.66344212601459e-20 5.62746587491021e-11 1 2.51891066089621 -8.11136165879707 0.906013465048411 -0.776796496613853 2.65836017225097 -0.292208898072717 0.770245276353204 0.743339733110079 4.87380821385936 0.152517230980958 0.8788390847329 GRM2 other 1 1 1 -0.292208898072717 0.152517230980958 0.0263246947379533 40.4264486878627 20.714653296609 1.95158702919158 0.0515237267510054 97.9546344168554 37.8709550125896 2.58653721260243 0.00996511848958771 DUSP7 other 1 1 1 1.95158702919158 2.58653721260243 1.37072929377644e-05 58.7023172708804 14.1201203845924 4.15735246385966 3.76402213765475e-05 -0.275912410297401 25.8259786454475 -0.0106835219716267 0.991480034481677 POC1A other 0.0823671232630265 1 0.323404782067296 4.15735246385966 -0.0106835219716267 6.09255503726961e-20 28.0886720703288 14.8095664717164 1.89665728054722 0.0584260252225413 -202.217116204111 27.0818319477337 -7.46689206972327 3.47780325843965e-13 PPM1M other 7.20627409808249e-16 5.1346287307603e-09 1 1.89665728054722 -7.46689206972327 8.53198362579555e-21 236.85578724544 71.9647176213954 3.29127654598093 0.00106464996061787 -874.913741205391 131.505415077073 -6.65306246661115 7.2540609556711e-11 WDR82 essential 1.02725082854578e-16 1.03907169129033e-06 1 3.29127654598093 -6.65306246661115 0.00276114621687511 6.40266026520167 3.93411630845721 1.62747101590205 0.104215052960863 29.851180326045 8.67053104632456 3.4428318365458 0.000619882782024781 PITX2 other 1 1 1 1.62747101590205 3.4428318365458 3.63919870598687e-14 263.017273559526 67.8943384020866 3.8739205617098 0.000120219609218915 -709.843662300575 143.264746661408 -4.95476855850812 9.69925053799035e-07 C4orf3 other 3.64101830533986e-10 0.0123277474337857 0.985440136767448 3.8739205617098 -4.95476855850812 3.53599504686376e-07 361.325898353993 66.3587456083433 5.44503810374263 7.87510287961337e-08 433.328770768675 139.730912696288 3.10116610853704 0.00202825790730857 PRSS12 other 0.00245539496054219 1 0.000809481824995458 5.44503810374263 3.10116610853704 3.47385103553605e-12 1173.9281171211 157.674117965701 7.4452810154706 3.85676976898897e-13 1022.83651431441 339.455701136336 3.0131664040122 0.00270687241996751 HMGB2 other 3.21504913338862e-08 1 4.73341353748016e-09 7.4452810154706 3.0131664040122 1.16564805074986e-06 70.6080625881505 13.3378560371436 5.29380901934461 1.74666524605947e-07 61.6099631393101 28.5086734553784 2.1610954026234 0.031127682866314 SAP30 other 0.00773290916867458 1 0.00175889190278189 5.29380901934461 2.1610954026234 0.000164648068555261 46.8866051112507 28.5265357405118 1.64361370541972 0.10083700420605 257.263677943805 61.1681370097049 4.20584458707624 3.04414772096155e-05 SCRG1 other 0.869341801971776 0.355952193012035 1 1.64361370541972 4.20584458707624 0.145897762524139 -5.14793837859824 3.04336956935163 -1.6915258765944 0.091311234683664 1.28066687149251 6.53238733146475 0.196048826640129 0.844645430333929 HAND2 other 1 1 1 -1.6915258765944 0.196048826640129 2.81217983789988e-31 380.436502048905 30.0332249935217 12.6671878271803 2.15011237634328e-32 366.844410187056 72.3491654955238 5.07047189382927 5.45609451279712e-07 MAD2L1 essential 3.8957127294427e-27 0.00701053583949302 3.18797162040418e-28 12.6671878271803 5.07047189382927 0.00127938285114599 728.02347701264 222.177866011411 3.27675969745452 0.00111738743359234 -189.466928885758 536.365702368601 -0.353242066092348 0.72404457309033 ANXA5 other 1 1 1 3.27675969745452 -0.353242066092348 3.1042733592987e-17 191.844028721843 31.032252819263 6.1820851305632 1.24091403512689e-09 -265.941469711569 69.808737765764 -3.80957281599774 0.000155049702171812 MAP9 other 3.43363676272029e-13 1 1.37629775635923e-05 6.1820851305632 -3.80957281599774 0.0880953583679179 202.601068043027 91.9801954787977 2.20265968112374 0.0280373705314284 136.31452953533 207.866829060683 0.655778173705315 0.51224410458209 GUCY1A3 other 1 1 1 2.20265968112374 0.655778173705315 4.48283676884034e-34 52.7064198024362 10.617377391819 4.96416561806008 9.26077605459018e-07 -205.518563047069 22.6423606164017 -9.07672863836446 2.07672210485518e-18 FBXO8 other 6.35217970144676e-30 3.18112292021717e-14 0.00893016634944131 4.96416561806008 -9.07672863836446 3.33988689796293e-19 37.5141360532777 9.63961951883022 3.89166148933543 0.000111980470867461 -129.157567322925 20.5572179734741 -6.28283299275139 6.84153265161697e-10 CEP44 other 3.8826185188819e-15 9.62056321470378e-06 0.920479470530532 3.89166148933543 -6.28283299275139 0.737484470444439 61.193408301269 148.18228253814 0.412960357021889 0.679799275895892 -133.854186456936 316.009929229359 -0.423575888211363 0.672043489736222 HPGD other 1 1 1 0.412960357021889 -0.423575888211363 4.56510940015472e-12 32.0196004792217 36.8215574527323 0.869588433903839 0.384910289914548 -528.905705600404 81.7721028787243 -6.46804578799716 2.22013382920265e-10 TMEM144 other 4.20309622472245e-08 3.15436614453112e-06 1 0.869588433903839 -6.46804578799716 2.77021570760684e-05 207.636392635786 471.781599014498 0.440111257135752 0.660032305523037 -4285.54132110727 1047.90288306318 -4.08963596758126 4.97760066242749e-05 FAM198B other 0.161309660653946 0.574464892450756 1 0.440111257135752 -4.08963596758126 0.0139086709607225 -709.624849944558 1708.63800878498 -0.415316085850845 0.678075191060146 -10901.6704986164 3827.70786906183 -2.84809365592687 0.0045654665850261 NPY1R other 1 1 1 -0.415316085850845 -2.84809365592687 0.0921337951054885 -10.9658055936147 32.4628942197155 -0.337795069022371 0.735648657250151 -154.861605454792 72.6877995605794 -2.13050341860642 0.0335804991307714 NPY5R other 1 1 1 -0.337795069022371 -2.13050341860642 7.22450005549986e-21 474.169735522667 49.5795575700978 9.5638153860543 4.02515421939672e-20 67.9317583563512 108.977098351556 0.623358112703696 0.533312898650467 NAA15 other 8.71130216692174e-17 1 5.54263736010928e-16 9.5638153860543 0.623358112703696 0.234241246039878 9.7674918828554 5.73743370764038 1.70241476948976 0.0892542160411545 9.15703618387843 13.1974091774629 0.693851047637122 0.48807453901238 IL15 other 1 1 1 1.70241476948976 0.693851047637122 2.76817579701466e-06 61.4727737423179 12.1352849908472 5.06562258642318 5.60642496706138e-07 70.9103593239638 27.3549057120916 2.59223555987691 0.00979512495978539 FAM160A1 other 0.0177357023314729 1 0.00547635590782556 5.06562258642318 2.59223555987691 1.59138929376431e-36 203.235921462867 29.627503937193 6.85970447911185 1.89228436056207e-11 -578.033334270353 66.7159441795363 -8.66409583764316 5.27511041709359e-17 ARFIP1 other 2.2903274715856e-32 8.02713552169131e-13 2.2257048648931e-07 6.85970447911185 -8.66409583764316 1.09304267756259e-13 266.178758203312 33.5651174719908 7.93021977132751 1.26120272580611e-14 204.709015464036 152.536313309331 1.34203463439491 0.18014771446099 ICE1 other 1.07336790936646e-09 1 1.60197970231892e-10 7.93021977132751 1.34203463439491 7.1913152315141e-33 54.787780265586 4.71345676068228 11.6236942539928 5.09495651416301e-28 -15.6131216908069 10.9297004184694 -1.42850408456058 0.153727102239405 ANAPC10 essential 1.01037979002773e-28 1 7.42233264983268e-24 11.6236942539928 -1.42850408456058 4.21906431176107e-19 487.449383547265 52.1059722829748 9.35496186310557 2.24407714853394e-19 171.776805694005 120.824841720526 1.42170106120505 0.1556924757897 ABCE1 essential 4.89284888234931e-15 1 3.06698023890133e-15 9.35496186310557 1.42170106120505 2.75055486610644e-11 246.158595461002 39.8847615338373 6.17174544850085 1.33022804696596e-09 -106.905173953991 92.485943323649 -1.15590726668466 0.248232145982453 OTUD4 other 2.44029227720963e-07 1 1.47375965323358e-05 6.17174544850085 -1.15590726668466 6.5895215563581e-13 55.7952812261295 7.4965728006178 7.44277187857515 3.9238028950803e-13 78.1709785551063 17.387507779772 4.49581271480711 8.48997115313827e-06 LSM6 other 6.26663500009655e-09 0.102983350087567 4.81450615226353e-09 7.44277187857515 4.49581271480711 5.95417841690025e-24 170.159887100425 24.4065260088593 6.97190116441232 9.14473264049689e-12 -291.032500672503 55.9078002360087 -5.20557953351663 2.75119904184198e-07 TMEM184C other 7.56954702140528e-20 0.00357325731554436 1.08630279036463e-07 6.97190116441232 -5.20557953351663 7.05438346040381e-19 26.8574214428619 6.52226437976455 4.11780631373784 4.4230023076689e-05 -96.5298572864626 14.9404898467709 -6.46095665379577 2.32215683759558e-10 PRMT9 other 8.12523886969311e-15 3.29792714075324e-06 0.377547476982617 4.11780631373784 -6.46095665379577 0.0127731434060847 -43.3818501099338 91.2878461416434 -0.475220436712045 0.634828641245666 -631.331755773091 218.931282045231 -2.88369825396929 0.00409255606237817 ITGA2 other 1 1 1 -0.475220436712045 -2.88369825396929 3.51974584208252e-20 163.250291313517 29.472472566657 5.53907687739123 4.80643864447893e-08 -378.880926647878 70.238846654433 -5.39417921413101 1.04134725824261e-07 MOCS2 other 4.18216200956245e-16 0.00137759828792915 0.000499725425866474 5.53907687739123 -5.39417921413101 0.150240298447244 -77.5676075967909 88.5401184115783 -0.876073004965029 0.381376307111142 -384.755892447534 197.551096536697 -1.94762721742757 0.0519726912829124 EDIL3 other 1 1 1 -0.876073004965029 -1.94762721742757 7.4230597740645e-26 45.8475826035966 11.2436545371373 4.07764063296004 5.22933191496061e-05 -203.349898041902 25.1366539006923 -8.08977594413638 3.91658002182912e-15 TMEM161B other 9.71084679643118e-22 5.8858364568048e-11 0.44344734638866 4.07764063296004 -8.08977594413638 0.811585708129456 -3.84016137990974 19.1045412837124 -0.201007777307047 0.840768602954198 20.9159287994824 43.8274517729991 0.477233513547966 0.633390013101701 ELOVL7 other 1 1 1 -0.201007777307047 0.477233513547966 1.14384882060962e-10 45.3561728192719 7.19698630961318 6.30210630784285 6.10177607086415e-10 0.293001696509783 16.4806963135037 0.0177784779803088 0.985822140854023 NDUFAF2 other 9.83481215960149e-07 1 6.84985381715209e-06 6.30210630784285 0.0177784779803088 2.89548997499315e-13 145.903631385632 24.2360628818162 6.0201045069536 3.21470743112895e-09 -494.420838344562 121.715634240928 -4.06209803225351 5.58180409569511e-05 LMBRD2 other 2.7978997915096e-09 0.641628380800153 3.50628139513235e-05 6.0201045069536 -4.06209803225351 0.208728073648473 -7.02155601629275 7.53683018388219 -0.93163250928867 0.351941265218004 -61.5193648839727 37.8506224575635 -1.62531976727584 0.10467574041167 RANBP3L other 1 1 1 -0.93163250928867 -1.62531976727584 5.79421267306927e-11 274.344768705564 50.1926887221142 5.46583129316784 7.04842421889826e-08 -902.028493481668 252.003657660747 -3.57942619505943 0.000375372361884813 NIPBL other 5.05892708485678e-07 1 0.000726340115757465 5.46583129316784 -3.57942619505943 1.68340639376177e-05 -4.03364185652013 7.19265329028778 -0.560800262952581 0.575166318254057 -71.5608097279953 15.8714637204808 -4.50877190587356 8.00239174875542e-06 RNF180 other 0.100331021068201 0.0971810453968858 1 -0.560800262952581 -4.50877190587356 1.00958923704711e-07 169.570364269524 50.4203107941653 3.3631360378117 0.000824964414218378 -331.865270529124 112.15772259248 -2.95891591642728 0.0032218616958102 ADGRV1 other 0.000730033977308769 1 1 3.3631360378117 -2.95891591642728 9.15968371387245e-24 118.909811796871 30.2057918170784 3.93665600680064 9.33311673527158e-05 -524.477443147318 67.1170122916519 -7.81437410932777 2.86260443128574e-14 SLC25A46 other 1.16144789491903e-19 4.26986076970581e-10 0.773435383851956 3.93665600680064 -7.81437410932777 5.53212294763533e-05 -11.8021768803353 8.04438568410955 -1.46713215201114 0.142916913759971 59.9366633319887 17.9351116801228 3.34186172915865 0.000889251617616273 STARD4 other 0.310849988427629 1 1 -1.46713215201114 3.34186172915865 8.9020891888879e-38 56.1535529735907 20.190260408161 2.78121984751089 0.00560432432315118 -532.64416150447 45.1176385829996 -11.8056746370847 8.87126464587389e-29 PGGT1B other 1.29017978614552e-33 1.38711094002884e-24 1 2.78121984751089 -11.8056746370847 6.81863186749284e-08 -106.70139386079 54.0325605318588 -1.97476101096258 0.048802370553348 -694.825114252267 119.595162686456 -5.80980951607466 1.06737843492742e-08 F2RL2 other 0.000499055666381801 0.000145771872858037 1 -1.97476101096258 -5.80980951607466 6.26895368494888e-05 29.6349220580064 8.3007404007058 3.57015406185773 0.000388531913275023 -20.2683770858974 18.5490329396132 -1.09269184824252 0.275015451892151 CCDC112 other 0.349744926083298 1 1 3.57015406185773 -1.09269184824252 0.239789506839237 16.4921180321778 9.96181394265596 1.65553363344395 0.098393012940142 -5.60696375919945 48.7497011750564 -0.115015346228796 0.908475397797925 ANKRD33B other 1 1 1 1.65553363344395 -0.115015346228796 3.90352885757029e-10 294.599673087072 71.036561124695 4.14715561145961 3.90273309319485e-05 -1560.08518079332 330.499325885577 -4.72038838994015 2.99542766073527e-06 CMBL other 3.26803435955784e-06 0.0372032115463321 0.334854499396118 4.14715561145961 -4.72038838994015 4.12648536903409e-25 37.5440313669303 6.39884139313895 5.8673170751171 7.6847015127298e-09 -96.9613358222605 14.8251183098424 -6.54034145264716 1.41297265687389e-10 C5orf63 other 5.33678352777179e-21 2.01405122510805e-06 8.26412800678963e-05 5.8673170751171 -6.54034145264716 3.89420297368932e-13 195.866027148087 69.6169364090616 2.81348242613262 0.0050773841096805 -904.2380776646 161.077147283685 -5.61369562916384 3.15500333331627e-08 PRRC1 other 3.73765601414701e-09 0.000424347948331038 1 2.81348242613262 -5.61369562916384 0.242916858700295 -14.3650646391407 15.8658300906702 -0.905408954781885 0.365651068651133 -58.6797167725967 35.1600356269413 -1.66893223303885 0.0957082932233739 F2RL1 other 1 1 1 -0.905408954781885 -1.66893223303885 5.95555586013238e-35 118.452776709409 23.3399189239024 5.07511517480474 5.33348881199839e-07 -481.571698464091 51.7948714575977 -9.29767146653378 3.515700118066e-19 AGGF1 other 8.4938137677208e-31 5.39730282125492e-15 0.00522095219806523 5.07511517480474 -9.29767146653378 0.000324608184215287 73.8888569913598 22.9571284569634 3.21855832840224 0.00136513702362964 -43.3262418438911 50.687256958476 -0.854775824215243 0.393051540361392 WDR41 other 1 1 1 3.21855832840224 -0.854775824215243 3.68999520649388e-40 144.383869171814 17.885007115959 8.07289973303831 4.6231645745741e-15 -340.85414753701 42.206290547228 -8.07590866474278 4.52274719240496e-15 NDUFS4 other 5.40805697463744e-36 6.792714008273e-11 5.91765065545485e-11 8.07289973303831 -8.07590866474278 0.418585576147043 8.16170312919414 16.8895337709097 0.483240285960513 0.629121002397673 52.073455751121 39.4654165875644 1.31947057078651 0.187570997795918 ESM1 other 1 1 1 0.483240285960513 1.31947057078651 0.000325394397241717 52.8122280995831 13.9576413600563 3.78375018652649 0.000171502963640488 -0.375593563939389 33.2068312610853 -0.0113107318487068 0.990979650518171 GRPEL2 other 1 1 1 3.78375018652649 -0.0113107318487068 0.00461223695959002 88.71988854731 35.9328631685678 2.46904590182832 0.013855760974831 -81.8143300179345 83.8249706897307 -0.97601382195243 0.329494636825558 CDC20B other 1 1 1 2.46904590182832 -0.97601382195243 5.40871652774116e-05 9.27697663878704 5.39137930324216 1.72070561483371 0.0858728824802606 -39.0137043478471 12.4898010271635 -3.12364498545638 0.00188137426865662 ARSK other 0.304186217520163 1 1 1.72070561483371 -3.12364498545638 0.000192440736801407 586.054780061054 192.15282898715 3.04994094102172 0.00240034675471966 -633.206909437826 446.217216621942 -1.41905530725927 0.156455586070858 RHOBTB3 other 1 1 1 3.04994094102172 -1.41905530725927 0.0708095812584695 -18.0172080696494 42.7829458632941 -0.421130609547562 0.673827275182609 -223.634858361804 99.8049937236301 -2.24071812459676 0.0254500730453206 GPX8 other 1 1 1 -0.421130609547562 -2.24071812459676 7.13760310409939e-32 20.3208490250698 6.20902711815241 3.27279115365124 0.0011323737473262 -154.998379559507 14.7319365600258 -10.5212494588176 1.07766425451493e-23 TIGD6 other 9.93482976059595e-28 1.6744747186653e-19 1 3.27279115365124 -10.5212494588176 9.01155897386437e-07 257.26620220908 73.5318467464839 3.49870448781272 0.000505876731626244 -376.802742040019 162.823703734005 -2.31417621266974 0.0210303706325628 SERINC5 other 0.00605126185094993 1 1 3.49870448781272 -2.31417621266974 0.00954325211010767 -1.22141152133156 2.31498065926629 -0.527611976559094 0.597983403103352 12.0884407366348 4.82393136434479 2.50593132936847 0.0125032746754302 ENPP6 other 1 1 1 -0.527611976559094 2.50593132936847 8.75244262155696e-18 216.725843403526 25.9741717073204 8.34389815566072 5.9302228055532e-16 5.99978611788482 54.4327242840508 0.110223880887821 0.912272399057755 CASP3 other 9.82811781974631e-14 1 7.71581289230527e-12 8.34389815566072 0.110223880887821 6.40755641176169e-28 47.8985363595351 7.13751909140127 6.71081026140296 4.86335715676763e-11 -88.902168539955 14.9577285140106 -5.94356077907701 4.98057644205758e-09 PRIMPOL other 8.58868861432537e-24 6.86672074066478e-05 5.64878933758561e-07 6.71081026140296 -5.94356077907701 1.81583961698878e-14 337.278402797296 72.2479019637614 4.6683487496491 3.82722973813898e-06 -736.660909643525 167.404892224598 -4.40047420272035 1.29987337352331e-05 ERAP1 other 1.83708494050755e-10 0.155893813686651 0.0354899013617628 4.6683487496491 -4.40047420272035 0.00943251385447795 142.941061079863 66.4761517901324 2.15026076616368 0.0319730189334738 -180.789252795057 153.787854174262 -1.17557562504383 0.240276853547981 ERAP2 other 1 1 1 2.15026076616368 -1.17557562504383 0.328795387347334 457.555934938746 570.860026911203 0.80152036115487 0.423184976716425 -1047.64183378889 1270.54872710555 -0.824558563901385 0.409988352478644 CMYA5 other 1 1 1 0.80152036115487 -0.824558563901385 0.315074628766981 3.13707451875612 13.7913263667897 0.227467209122856 0.820147200833883 -96.4646922919796 67.5562740944585 -1.42791611267816 0.153898379325837 EGFLAM other 1 1 1 0.227467209122856 -1.42791611267816 2.09925587488526e-18 193.804043810905 43.8260263753697 4.4221221917537 1.17985911631763e-05 -504.607426674088 92.0365762578613 -5.48268359375208 6.41152947069898e-08 CFAP97 other 2.39504102765659e-14 0.000854015725497104 0.105702971568087 4.4221221917537 -5.48268359375208 0.558429220079656 -447.423998829334 1205.25014912745 -0.371229158654947 0.710612997768728 -3101.54128125533 2875.16608460701 -1.0787346504469 0.281189432054356 CARTPT other 1 1 1 -0.371229158654947 -1.0787346504469 8.67850813141829e-06 50.0053421753632 26.0650041594958 1.91848586976518 0.0555773398020996 -491.054408860677 121.24967146408 -4.0499442425801 5.87509631372646e-05 RICTOR essential 0.0530430416992286 0.6739910491107 1 1.91848586976518 -4.0499442425801 1.32742699697082e-29 96.9829265777834 27.0863147123804 3.58051390924196 0.000373615684430635 -551.117983013476 59.9750557160346 -9.18911998386243 8.31711383936049e-19 PAPD4 other 1.80928299687122e-25 1.27542940726593e-14 1 3.58051390924196 -9.18911998386243 0.330647438175828 42.684557489324 32.2588450839119 1.32318926416282 0.186326278521779 -14.5845580877017 75.0260614193742 -0.194393225657658 0.84594029906914 EBF1 other 1 1 1 1.32318926416282 -0.194393225657658 8.75155255600279e-53 49.0869373495951 9.63578760409291 5.09423197837455 4.82803260134488e-07 -301.871950007118 22.7231557562535 -13.2847722933045 4.19004356446381e-35 ANKRA2 other 1.3304985350891e-48 6.56537926115834e-31 0.00474161081778081 5.09423197837455 -13.2847722933045 0.000484756214013151 37.4090334622917 15.5780836120932 2.40138866845285 0.0166662674726322 -77.0157194527297 36.5915236924059 -2.10474207360524 0.0357701477002611 UBLCP1 other 1 1 1 2.40138866845285 -2.10474207360524 1.13548093447109e-32 67.3352164925461 9.7568049154567 6.90135931547364 1.43073409219311e-11 -171.368391659451 23.0085393002156 -7.44803437643019 3.71327249643662e-13 UTP15 essential 1.59194427012848e-28 5.48079020474045e-09 1.6899831096985e-07 6.90135931547364 -7.44803437643019 5.68502536349831e-09 -38.6899199077897 16.4675585422905 -2.34946302503979 0.0191571020516531 -216.404406815123 34.5687980196181 -6.26010793584178 7.80946789837866e-10 TLR3 other 4.46786143317332e-05 1.09683976632728e-05 1 -2.34946302503979 -6.26010793584178 6.38295400723189e-06 1.18313176445106 2.63933055496084 0.44826964255283 0.654137415971427 -23.6546896139548 5.54774743527136 -4.26383678960645 2.3699707233399e-05 KLKB1 other 0.0394259368026807 0.279206250916674 1 0.44826964255283 -4.26383678960645 2.55131187126191e-37 177.330207431496 36.7164242505696 4.82972432776443 1.77739961963115e-06 -882.323751040954 85.825565789886 -10.2804303463727 8.74516759716988e-23 NSA2 essential 3.68919696584472e-33 1.35690020437688e-18 0.0168444161952445 4.82972432776443 -10.2804303463727 2.97875443717663e-35 145.529005471411 21.5571917099418 6.75083319894098 3.77259603101959e-11 -416.956384712065 50.3424338564062 -8.2824041821531 9.39433233914116e-16 GFM2 other 4.25842734338771e-31 1.41854418321032e-11 4.39771519335954e-07 6.75083319894098 -8.2824041821531 3.25327536056428e-19 87.4692792107497 11.1274960216265 7.86064349434513 2.20928719386909e-14 -190.785652688919 48.4418805499591 -3.93844438991501 9.31701107478134e-05 CCDC127 other 3.78355924433626e-15 1 2.79055065457605e-10 7.86064349434513 -3.93844438991501 0.235566439384897 15.3051087319139 10.0096996225363 1.5290277739659 0.126876317940777 36.4086152099164 28.7296380587275 1.26728415914924 0.205630923661687 FOXQ1 other 1 1 1 1.5290277739659 1.26728415914924 8.14200555581746e-06 8.07820574788048 11.3841484270504 0.709601231892362 0.47825492663543 126.871132381132 26.7877637447605 4.73615989710775 2.78132359608381e-06 ACSL6 other 0.049869784029382 0.0346080095060708 1 0.709601231892362 4.73615989710775 2.94477748359607e-10 107.111352183047 71.1421847572361 1.50559548527432 0.13275574189468 -911.046407738235 166.266146206387 -5.47944622838224 6.55347845743078e-08 SEPT8 other 2.48244741867149e-06 0.000872333517468611 1 1.50559548527432 -5.47944622838224 7.77627347459136e-05 350.814769003805 207.272208060868 1.69253163405672 0.0911301512525258 -1477.06503319918 483.498534813476 -3.05495244937816 0.0023637927764423 SHROOM1 other 0.428939244858459 1 1 1.69253163405672 -3.05495244937816 0.174427964468621 -70.9338012745164 145.709079514873 -0.486817990414082 0.626585217052182 -629.169374291079 339.421751892491 -1.85365071856197 0.064335321210208 GDF9 other 1 1 1 -0.486817990414082 -1.85365071856197 6.56115413488934e-15 467.596035728647 127.057688078695 3.68018687258841 0.000256406491124583 -1610.48750666641 295.920593185527 -5.44229615563361 7.98494404956281e-08 UQCRQ essential 6.7533959510416e-11 0.00106064011810343 1 3.68018687258841 -5.44229615563361 0.0686238708021767 -2.07654931187674 6.89594954159868 -0.301125943475993 0.763433944021232 -35.9077083337166 16.059394585684 -2.2359316313036 0.0257625000072321 LEAP2 other 1 1 1 -0.301125943475993 -2.2359316313036 1.18482086768895e-17 112.556022443765 25.7963702020755 4.36325039383678 1.53462881864207e-05 -241.724836421596 56.7505111396787 -4.25943011908113 2.41634471209602e-05 SLC35A1 other 1.32510365842332e-13 0.284524589849307 0.136106229925365 4.36325039383678 -4.25943011908113 0.0358607743187481 3.37010220911961 2.29380758728915 1.46921748266708 0.142375048593604 -5.16343435695635 5.0465864840939 -1.02315384334158 0.306708126433338 GRIK2 other 1 1 1 1.46921748266708 -1.02315384334158 0.376845918783104 291.3001648734 357.328525990696 0.815216652702911 0.415313111559542 -501.399989369713 818.314933660553 -0.612722521299727 0.540321650266867 FABP7 other 1 1 1 0.815216652702911 -0.612722521299727 0.159724513735731 16.415104429669 39.1403844574121 0.419390475010024 0.675102008550682 -129.731172098853 88.4765576176408 -1.46627734613611 0.143170300574901 TXLNB other 1 1 1 0.419390475010024 -1.46627734613611 9.76426701979523e-05 -190.225528735565 114.160756878623 -1.66629526587507 0.0962510877692057 -1107.31158299956 256.407278962301 -4.31856532108188 1.87818359779966e-05 CITED2 other 0.531078483206663 0.222959174894798 1 -1.66629526587507 -4.31856532108188 1.40566520355626e-15 13.893081623682 20.8949530373693 0.66490130888713 0.506399054801454 -447.81187408455 57.8438895594113 -7.74173171091137 4.90606521604809e-14 CREBRF other 1.47890036066154e-11 7.30365928713079e-10 1 0.66490130888713 -7.74173171091137 1.25459038821136e-05 68.1393801063618 17.7240444868595 3.8444600021671 0.000135208096761372 -65.4003477914863 56.0299018454248 -1.16724009211925 0.243628582827333 DCBLD1 other 0.0756016167936166 1 1 3.8444600021671 -1.16724009211925 1.11552159486127e-10 198.655690849721 44.8800138414049 4.42637320816615 1.15922649494747e-05 -419.968984497124 125.267922826418 -3.35256604421444 0.000856552345940387 SFXN1 other 9.59906332378123e-07 1 0.10393624753699 4.42637320816615 -3.35256604421444 0.867161299873026 1.12191942922521 2.27192806567979 0.493818200572965 0.621635370364834 0.219891535929308 5.42343178754791 0.0405447223350674 0.967673838736176 SAMD3 other 1 1 1 0.493818200572965 0.0405447223350674 0.987440456875978 1.10983742981338 12.1174454574012 0.0915900495459213 0.927057786160306 -2.17750219582814 28.8879672083804 -0.0753774808771053 0.939942343689178 TMEM200A other 1 1 1 0.0915900495459213 -0.0753774808771053 0.00378869546426727 6.79088279942504 2.16108904000371 3.14234289921408 0.00177045133115601 1.88342954340542 4.91815217381538 0.38295471080235 0.701908052232422 IL22RA2 other 1 1 1 3.14234289921408 0.38295471080235 0.848412501727764 -1.89865299344801 3.67646633575194 -0.516434211564646 0.60576259159437 -0.291936005031692 7.57427987412879 -0.0385430707450946 0.969268936208913 DACT2 other 1 1 1 -0.516434211564646 -0.0385430707450946 1.90531245111509e-101 211.729318430746 8.33299642267059 25.4085454608765 1.5879154331128e-93 22.0975305779011 27.9988014538713 0.789231303858038 0.43033242483082 PDSS2 other 2.97628857988688e-97 1 2.47905357417571e-89 25.4085454608765 0.789231303858038 0.000300998879897008 19.9782440418685 30.1876039051556 0.66180290773116 0.508379845322684 -212.532909172487 66.036840014858 -3.2183991409139 0.00136645916350315 STXBP5 other 1 1 1 0.66180290773116 -3.2183991409139 4.88092223842974e-05 10.0418372712442 2.94545240633698 3.40926821619651 0.000699575414659602 -8.91640607384062 7.33714272095338 -1.21524228339967 0.224799883894824 RAET1E other 0.276309007917508 1 1 3.40926821619651 -1.21524228339967 0.726587590762529 -24.6501773291191 47.4104661352298 -0.519931132058666 0.603322690622827 -120.23044842892 161.544511978057 -0.744255852190454 0.457042474223805 PI16 other 1 1 1 -0.519931132058666 -0.744255852190454 5.59322064086511e-25 76.7406363517583 10.7980215129999 7.10691641606466 3.72723579456793e-12 -241.911520335546 37.9576219370038 -6.37320011082448 3.94031847827366e-10 DAGLB other 7.22476310180546e-21 5.56964016903982e-06 4.47342840064043e-08 7.10691641606466 -6.37320011082448 4.70587947237718e-06 40.7188845219358 12.6071982245069 3.2298123498037 0.00131350377333889 -139.187660885433 48.2904903925957 -2.88229959467909 0.00410383667636427 KIAA0895 other 0.0294635113765535 1 1 3.2298123498037 -2.88229959467909 0.187936650782427 39.6366829223344 22.7059458508845 1.74565213810683 0.0814318476195146 -12.1167660890161 87.6939640688118 -0.138171038539304 0.890155998955206 STK17A other 1 1 1 1.74565213810683 -0.138171038539304 1.20036647331803e-10 73.134828822676 25.0712245917042 2.91708243269758 0.00368106042501167 -629.633238709123 115.789978983137 -5.43771787713011 8.20639192343863e-08 TRA2A other 1.03027454404887e-06 0.00108966742337988 1 2.91708243269758 -5.43771787713011 3.79880257458038e-15 -13.4883087736678 133.096126992332 -0.101342609123741 0.919315902328784 -2445.95476318937 307.531719829739 -7.95350399803814 1.05955403732735e-14 GALNT10 other 3.94087779086968e-11 1.58657621549398e-10 1 -0.101342609123741 -7.95350399803814 1.86540941029019e-15 116.807315171948 29.7790711255853 3.92246335284753 9.8886597753558e-05 -400.638171799299 69.1148850642877 -5.79669880701737 1.14787320957737e-08 SAP30L other 1.95382981633794e-11 0.000156558427054258 0.817792163421925 3.92246335284753 -5.79669880701737 3.39086401842934e-11 878.056165186431 407.291036205215 2.15584456109665 0.0315335928143956 -5433.60417021457 966.235844410067 -5.62347609193907 2.99562047639436e-08 RPS14 essential 2.99582836028233e-07 0.000403390253351265 1 2.15584456109665 -5.62347609193907 0.0400782151719686 34.4194546253396 16.7921160739841 2.04973896521983 0.0408679359243683 -28.4691804921461 39.5967560436351 -0.718977596568098 0.472462872160749 MYOZ3 other 1 1 1 2.04973896521983 -0.718977596568098 1.16849882142148e-17 138.206401690595 41.0333505050557 3.36814810366428 0.000810516354526731 -856.862691538834 121.764924283176 -7.03702397536187 5.95862624170433e-12 COG5 other 1.30719963152421e-13 8.67873912104235e-08 1 3.36814810366428 -7.03702397536187 2.22021937897859e-09 24.9271619609017 6.93254595694738 3.59567208291222 0.000353390883407753 -85.1386762868835 21.4469477893744 -3.96973392778363 8.17421435101136e-05 BMT2 other 1.78661053426407e-05 0.927364618122239 1 3.59567208291222 -3.96973392778363 0.975307314505086 0.0452679280246623 1.32094257302089 0.0342694140905296 0.972675024920534 0.897623054571979 4.06825266723617 0.220640930638606 0.82545573340988 GPR85 other 1 1 1 0.0342694140905296 0.220640930638606 5.70686938610918e-37 202.462349464954 24.7298534789725 8.18696114140366 1.90247052802799e-15 -456.967700730088 58.1633512991762 -7.85662604583377 2.10989150697327e-14 SLU7 other 8.23558321109416e-33 3.15175593311667e-10 2.45285525178648e-11 8.18696114140366 -7.85662604583377 6.90647626941559e-09 33.5922407450828 5.46530492448078 6.14645316396031 1.53159741592288e-09 5.91625100031455 22.756830776545 0.259976929934036 0.794979753083116 RP9 other 5.40155509030993e-05 1 1.69027090821249e-05 6.14645316396031 0.259976929934036 2.15276357330746e-07 108.565732170918 31.9502157925432 3.39796553725488 0.000728401076809286 403.227554314822 75.1452743869386 5.3659735439719 1.19168706004897e-07 PTTG1 other 0.0015200663591124 0.00157243107573461 1 3.39796553725488 5.3659735439719 1.43032477370742e-40 150.155647047601 23.0007560720887 6.5282917907996 1.5247033943296e-10 -523.698604810293 53.1262388710752 -9.85762621143171 3.32778226136745e-21 CAMLG essential 2.09943070284775e-36 5.14375304139566e-17 1.74639526786512e-06 6.5282917907996 -9.85762621143171 0.865015470586269 5.08140609308754 11.1151379459435 0.457160866360818 0.647737928337362 16.6930109862374 44.8863399701614 0.371895124381588 0.710115751246257 BMPER other 1 1 1 0.457160866360818 0.371895124381588 1.36757336374035e-07 39.7538143967723 7.10347140395837 5.59639254331617 3.48178359540808e-08 15.4131707119836 16.7823056653534 0.918417946814289 0.35880937202955 RELL2 other 0.000980276587129085 1 0.000364124928407777 5.59639254331617 0.918417946814289 4.07401311720508e-08 379.912525512028 66.8895877466087 5.6796960231122 2.20130951037169e-08 52.4456686289618 229.120270112386 0.228900169344409 0.819032692346745 KCNK5 other 0.000303228796313574 1 0.000232326205724628 5.6796960231122 0.228900169344409 0.712295129503227 -0.141289173740074 2.13770122835462 -0.0660939760271474 0.947327423572812 -5.79625649126176 7.25852769088066 -0.798544379536356 0.424905055847217 KIF6 other 1 1 1 -0.0660939760271474 -0.798544379536356 1.46829367997569e-11 59.3546535332212 19.7632177557557 3.00328895156433 0.00279340060254287 -391.575632352349 70.6142818299514 -5.54527529282695 4.58070396027915e-08 ZNF12 other 1.31955553019415e-07 0.000613264646202173 1 3.00328895156433 -5.54527529282695 8.66919111903178e-07 94.4678136548531 19.4715415905142 4.85158369283275 1.60330940800344e-06 230.621907319277 67.6097257268466 3.41107591903307 0.000695322269074442 SLC29A4 other 0.00582569643198936 1 0.0152426625418887 4.85158369283275 3.41107591903307 0.0843670672461935 28.0620882612536 18.2017167086069 1.54172755847717 0.123723427904503 -65.1508102383049 59.022553429859 -1.1038290696069 0.270157113674382 STEAP1 other 1 1 1 1.54172755847717 -1.1038290696069 4.88262439299095e-06 139.588044953742 28.2973957105443 4.93289369741286 1.07878555727545e-06 259.750394210044 127.879321976998 2.03121497826494 0.042719739585989 CDCA7L other 0.0305164024561935 1 0.0103617352776307 4.93289369741286 2.03121497826494 1.67520626874955e-11 49.1926494624842 18.7705070937684 2.62074163562772 0.00901871882925583 -392.061606745993 67.5164997608159 -5.80690065591243 1.08191621491706e-08 MIOS essential 1.50064977554584e-07 0.000147692382498328 1 2.62074163562772 -5.80690065591243 0.000350060750952692 56.7957048962657 33.2446661905008 1.7084155566734 0.0881328626641955 -331.669580120975 107.795676458072 -3.07683564887672 0.00219798727178052 KIAA1324L other 1 1 1 1.7084155566734 -3.07683564887672 2.06909125161291e-41 80.4868073892396 5.61553512624976 14.3328829006883 1.04674510679833e-39 -18.0156919292887 27.0113049520276 -0.666968588199823 0.50507761096956 USP49 other 3.04777141362582e-37 1 1.58110848381888e-35 14.3328829006883 -0.666968588199823 0.834993375820017 0.0304123276255905 3.4703291912071 0.00876352816979073 0.993011173142919 8.25350271997897 14.0219315437639 0.588613822155595 0.556376432192031 INTS4P1 other 1 1 1 0.00876352816979073 0.588613822155595 1.44368358572611e-09 22.2446119229654 6.77701887074608 3.2823594484866 0.00109560928939845 -47.5660421841564 14.3332299308768 -3.31858502330232 0.000965390779335683 SYTL3 other 1.17241543996817e-05 1 1 3.2823594484866 -3.31858502330232 0.0318854935202815 -0.575053497659608 1.98402582560944 -0.28984174008066 0.772048161127016 -15.9287260572127 6.20476860876863 -2.56717487171111 0.0105202563902087 IQUB other 1 1 1 -0.28984174008066 -2.56717487171111 0.451580727320804 -3.52830441766011 9.04936253000032 -0.389895355165972 0.696774499853104 -109.360246358993 89.0314885357597 -1.2283322244474 0.219881152849917 HEY1 other 1 1 1 -0.389895355165972 -1.2283322244474 8.14808903623878e-15 290.903250393662 37.9079999371844 7.673927690084 8.49454770590529e-14 -968.120265255446 395.022978008555 -2.45079481233236 0.01458751877789 ZNF704 other 8.35586530666287e-11 1 1.05952493535757e-09 7.673927690084 -2.45079481233236 0.097272733838398 38.4724272530766 17.7816513057273 2.16360261438064 0.0309513632124293 38.9185549267285 183.278477996329 0.212346563285559 0.831920202763318 FABP5 other 1 1 1 2.16360261438064 0.212346563285559 0.92856392621703 2.63578973058458 10.8620541226743 0.242660338534166 0.808359995763005 8.70802119139138 22.9638324740893 0.379205918751448 0.704682924705126 TAGAP other 1 1 1 0.242660338534166 0.379205918751448 0.0328881293109184 -17830.9734507503 6851.27334376975 -2.60257802543597 0.0095081795028715 -21988.9651420331 21846.4027874783 -1.00652566722044 0.314616087010658 COL1A2 other 1 1 1 -2.60257802543597 -1.00652566722044 0.00563356031536833 471.197887057543 152.560657110295 3.0885937172969 0.00211334324525539 748.177917499565 324.284522872245 2.30716505022448 0.0214188559099843 FNDC1 other 1 1 1 3.0885937172969 2.30716505022448 1.7594928336364e-26 140.82204284971 12.2368818854153 11.5080004995023 1.92324235603948e-27 37.695535306081 126.441989857577 0.298125135080055 0.765727430279845 CHMP4C other 2.31953940258287e-22 1 2.79312487367614e-23 11.5080004995023 0.298125135080055 0.0608317240822463 2.64577738120106 2.87807288331953 0.919287831984803 0.358351723756691 -16.4415463302534 9.30175496178204 -1.76757465637468 0.0776915529413627 SLC13A4 other 1 1 1 0.919287831984803 -1.76757465637468 0.231603551160988 83.2656935446797 51.0205347429906 1.63200354453594 0.103262799594845 -32.3875793492251 202.507764171935 -0.159932531385449 0.872994137610888 PGAM2 other 1 1 1 1.63200354453594 -0.159932531385449 1.40823574663638e-06 177.039179764016 47.6630711331887 3.71438884559707 0.000224888077060693 -362.509512484922 146.178519121464 -2.47990959727607 0.0134454063317056 BRI3 other 0.00927886533458711 1 1 3.71438884559707 -2.47990959727607 6.1029219406498e-14 126.270812781571 24.1203188667915 5.23503911697533 2.36306790349335e-07 -319.019913045569 74.0018957404153 -4.31096946711515 1.9310261260428e-05 LMTK2 other 6.0540985651246e-10 0.229019698548676 0.0023633042102837 5.23503911697533 -4.31096946711515 0.00025088484632945 2520.17511292772 803.281484731815 3.13734993377709 0.00179797472804272 -247.777760298811 1681.10679578183 -0.147389660740487 0.882879581216518 CTSB other 1 1 1 3.13734993377709 -0.147389660740487 0.0045847744336971 -10.9670576339121 3.73934082941205 -2.93288526888214 0.00351586148374937 -54.1501061428864 29.4584359199942 -1.83818673503074 0.0666412616606425 SOX17 other 1 1 1 -2.93288526888214 -1.83818673503074 0.0651803574173241 52.6537583624638 67.095316254024 0.784760566044816 0.432941313666924 -172.631206621858 138.622549751042 -1.24533278988082 0.21355459749111 DLC1 other 1 1 1 0.784760566044816 -1.24533278988082 0.0411055519791121 373.088656387669 225.513708182949 1.65439457935302 0.0986252499123444 -1413.21385406076 902.653403654806 -1.56562180825854 0.118019742226241 ADCY1 other 1 1 1 1.65439457935302 -1.56562180825854 1.70956499735987e-07 8.98979054784462 2.92475969185296 3.07368518955114 0.00222213328163193 -11.0851472064091 6.03792407641839 -1.8359202709592 0.0669242317216131 C8orf48 other 0.00121635549562154 1 1 3.07368518955114 -1.8359202709592 0.572883793694415 2.33878327076408 2.44455411381218 0.956732050867486 0.339149671786015 12.4403943145115 23.8131473422044 0.522417055408011 0.601603758375383 HNF4G other 1 1 1 0.956732050867486 0.522417055408011 3.63856746721061e-45 252.990577118851 16.2481927201445 15.5703825943173 4.32230200703512e-45 -299.536978336612 162.763015497842 -1.84032581001538 0.066294491907022 PEX2 other 5.43638365275937e-41 1 6.58416264731659e-41 15.5703825943173 -1.84032581001538 0.0466014544441069 653.724524595853 268.198128415392 2.43746862984572 0.0151258854267802 -1495.20403157616 3141.40287583259 -0.475966977390596 0.634298577630688 SLC30A8 other 1 1 1 2.43746862984572 -0.475966977390596 3.11426781198538e-34 47.0059079552298 3.60393543289263 13.0429384295327 8.1336613624335e-34 131.392035447731 42.1298510641492 3.11873961404864 0.00191750762859779 MED30 essential 4.42039173233205e-30 1 1.21118351347997e-29 13.0429384295327 3.11873961404864 0.34312694259798 1.30414963099144 7.69726890305963 0.169430176782969 0.865523551481982 -128.246306505332 88.4016292768066 -1.45072333569512 0.147454113602205 TNFRSF11B other 1 1 1 0.169430176782969 -1.45072333569512 0.219185456437826 -43.6640487757235 35.7591473735068 -1.22105956049929 0.222613643059608 -470.383286739854 348.230895971702 -1.35077987674614 0.177350075681585 SBSPON other 1 1 1 -1.22105956049929 -1.35077987674614 2.71018274431252e-05 103.943203920669 27.9497437149163 3.71893227289937 0.000221642235618336 -244.559687176561 120.837727411313 -2.02386864115805 0.0434906115882702 PHKG1 other 0.15792234851109 1 1 3.71893227289937 -2.02386864115805 1.23501233568473e-06 20.1321403959903 3.86784813069821 5.20499764098963 2.7542319535541e-07 11.0963356824515 11.9853863519067 0.925822110080434 0.35494895928457 EN2 other 0.00817454664989724 1 0.0027443167185213 5.20499764098963 0.925822110080434 0.775799809681427 3.36500287718228 7.88445368575588 0.426789605380207 0.669710932255289 -50.0602081032619 87.3145688293518 -0.573331676195984 0.566670401061456 CSMD3 other 1 1 1 0.426789605380207 -0.573331676195984 1.57594280743556e-40 355.810054077875 25.031149030103 14.2146912093396 3.97467362126891e-38 -615.667595800573 209.464123478376 -2.9392508157328 0.00345973433431471 SPIDR other 2.31253847563093e-36 1 5.98267873473397e-34 14.2146912093396 -2.9392508157328 7.09871169784449e-19 54.6129541244486 10.5757730466644 5.16396805070181 3.39696043159638e-07 -194.00494896639 32.0403981668833 -6.0550105512394 2.61935654906251e-09 ORC5 essential 8.1755862624075e-15 3.63566689009876e-05 0.00336808626792781 5.16396805070181 -6.0550105512394 2.51865617872582e-18 195.93861878563 23.5160685536995 8.33211632880725 7.19204931787812e-16 -166.094563208266 84.8663410301744 -1.95713119232053 0.0508697594738115 DNAAF5 other 2.86673446262573e-14 1 9.34031444912832e-12 8.33211632880725 -1.95713119232053 4.07792743599271e-34 296.636502029515 22.2005035390987 13.3617015265933 3.16825360043218e-35 72.4454860169714 218.857915394986 0.331016065314451 0.740765438891932 OSGIN2 other 5.78005434777607e-30 1 4.73812325944633e-31 13.3617015265933 0.331016065314451 1.47425772648822e-08 353.419904956003 57.8770710591497 6.1063889116782 1.96060081518859e-09 443.933129637305 125.679307590585 3.53226905962491 0.000447612620705557 DEFB1 other 0.000112854428962673 1 2.15568059629985e-05 6.1063889116782 3.53226905962491 1.66444466785388e-31 874.003457446846 74.4503293766246 11.7394169342823 2.24461455680073e-28 -480.402278823526 268.681264823557 -1.78800065996044 0.0743614240694226 SUN1 other 2.30958342111404e-27 1 3.27623940710634e-24 11.7394169342823 -1.78800065996044 4.38944163014261e-20 203.5385906731 20.7331041263909 9.81708235449503 5.35057433314554e-21 -229.571028616351 237.939318591612 -0.964830150709042 0.335074100409081 OXR1 other 5.20631671751215e-16 1 7.42766728927264e-17 9.81708235449503 -0.964830150709042 0.776089912774327 7.34532639504105 10.4250890338556 0.704581646371269 0.481387274084623 10.7236510728287 37.7450411799479 0.284107547312087 0.776441492036347 GPR146 other 1 1 1 0.704581646371269 0.284107547312087 0.320828891921789 32.2394471683879 37.8827799450041 0.851031714546588 0.395144961455431 195.538226163042 137.158261612107 1.42563943188517 0.15457475522713 GPER1 other 1 1 1 0.851031714546588 1.42563943188517 1.32898504511934e-14 216.573297207263 35.9579594157652 6.02295849725861 3.25682920426357e-09 -469.031211053163 122.696693559066 -3.82268826850962 0.000148122077375113 TMEM184A other 1.35104619686832e-10 1 3.55157224724942e-05 6.02295849725861 -3.82268826850962 0.0239724250690697 13.8327214732591 12.3152043777576 1.12322305411693 0.261838220445662 -75.489233527941 38.1716480099676 -1.97762573699278 0.0484752181160298 NOS3 other 1 1 1 1.12322305411693 -1.97762573699278 7.27512662850618e-08 94.9127219506338 29.579702528358 3.20871117144066 0.00141602192080994 -381.300836314907 100.282228578679 -3.80227725010865 0.000160477169368517 MICALL2 other 0.000531448000212376 1 1 3.20871117144066 -3.80227725010865 0.604577459707397 -7.69625438786595 8.37264177221904 -0.919214579728303 0.358413672479298 -38.2199445859701 91.538286436569 -0.417529605084473 0.676465084106359 CA3 other 1 1 1 -0.919214579728303 -0.417529605084473 4.09085613447854e-17 533.452129052198 75.8087763036355 7.03681229354727 6.27611056265428e-12 -899.434248120515 257.00978656776 -3.49961089082256 0.000506172883320655 INTS1 essential 4.51057797387603e-13 1 7.48551706807776e-08 7.03681229354727 -3.49961089082256 1.59447888462192e-24 121.869674288479 14.3793146822656 8.47534649469661 2.20775125929426e-16 -170.580244024794 44.5317694679542 -3.83052921684476 0.000142766330490825 CDK5 other 2.04649221426901e-20 1 2.89281647505327e-12 8.47534649469661 -3.83052921684476 2.24677313444354e-19 395.457461442243 65.0889649695319 6.07564525918266 2.32257594311322e-09 -1018.17031648887 201.576142325182 -5.05104574749901 6.00685411279653e-07 SLC4A2 other 2.62737650341827e-15 0.00770439108507283 2.54554323365209e-05 6.07564525918266 -5.05104574749901 1.02329834774132e-13 260.102164282032 50.2364534325526 5.17755825719754 3.16946596276981e-07 -612.304859260466 154.356727224127 -3.966816803335 8.25868717750541e-05 FASTK other 1.00610693549927e-09 0.936535125929114 0.00314696275443415 5.17755825719754 -3.966816803335 5.22085188119642e-11 99.2991404171136 26.2740983874965 3.77935482133875 0.000174611006812283 -349.960785585914 80.7298995201505 -4.33495876578618 1.73721401971669e-05 TMUB1 other 4.56667914048251e-07 0.206658979785497 1 3.77935482133875 -4.33495876578618 1.22796324419046e-11 60.0501498422587 10.2034723847847 5.88526607195063 6.94690649323708e-09 -62.216803081595 30.4425948740162 -2.04374178150954 0.0414592854467002 FMC1 other 1.10737725361096e-07 1 7.48598643711227e-05 5.88526607195063 -2.04374178150954 1.13695081613386e-26 110.568095321924 20.831666276726 5.3076932902605 1.6172112963666e-07 -356.664917951259 47.9517893049074 -7.43798976266269 3.98810521104492e-13 PHAX other 1.50236680843928e-22 5.88444923889679e-09 0.00163144275577463 5.3076932902605 -7.43798976266269 0.000162908106279841 132.220087826971 49.6542409573228 2.66281560804871 0.00797758385515501 -227.17852775547 114.297611571323 -1.98760520567579 0.0473544486324811 ALDH7A1 other 0.860969341688957 1 1 2.66281560804871 -1.98760520567579 0.0371523606661401 104.489472487286 41.6260076848169 2.51019682883013 0.0123565922744292 10.518433864536 143.333629567298 0.0733842706438786 0.941527407659404 FOXK1 other 1 1 1 2.51019682883013 0.0733842706438786 0.00872595330581615 1138.47878057373 529.682550647567 2.14936055413167 0.0320587399889489 -13828.9026677538 6479.76995357678 -2.13416568286044 0.0332883826783955 COX6C other 1 1 1 2.14936055413167 -2.13416568286044 0.193828066279919 14.9177333848354 9.66230778126394 1.54390997705146 0.123205869680633 -104.10783497341 115.851086855227 -0.898634944215141 0.369254437700154 OSR2 other 1 1 1 1.54390997705146 -0.898634944215141 4.78279566721248e-100 5812.82072047045 216.816390500772 26.8098768134864 3.00287520865996e-101 -473.432626056956 3018.39492789174 -0.15684913252476 0.875422483073477 YWHAZ other 7.46881371391901e-96 1 4.69229280105206e-97 26.8098768134864 -0.15684913252476 0.0356962836593455 30.1407761513615 12.1122604898369 2.48845177798578 0.0131343044641031 -100.140422631177 145.620696225912 -0.687679878111706 0.491953531804099 BAALC other 1 1 1 2.48845177798578 -0.687679878111706 1.99699788947206e-25 304.037496233264 27.1054146073826 11.21685466307 2.34953722469056e-26 370.581332831431 325.857486891642 1.1372497111127 0.25594586352723 FZD6 other 2.59589755652474e-21 1 3.39226184500823e-22 11.21685466307 1.1372497111127 0.539218772192328 8.22158921394511 38.9097873041646 0.2112987447008 0.832734926607306 -506.652067557206 465.181147761069 -1.08915004401132 0.276579917535652 CTHRC1 other 1 1 1 0.2112987447008 -1.08915004401132 1.86719740221703e-63 167.556634670134 8.61746299891492 19.4438473006768 4.80123232104703e-64 246.471588775235 105.38418712422 2.33879100367032 0.0197148663839377 SLC25A32 other 2.87884495473821e-59 1 7.4323076329808e-60 19.4438473006768 2.33879100367032 1.10164925472624e-72 432.048777245897 20.3107520870275 21.2719241215025 4.02121219913805e-73 675.81112949887 248.325764323519 2.72147004697597 0.00671218738682621 DCAF13 other 1.70744617990019e-68 1 6.25017012112028e-69 21.2719241215025 2.72147004697597 0.744582948084299 -1.01357644017312 1.60287486113742 -0.632349077740151 0.527430468282962 -8.47288802953493 19.4091912962304 -0.436539982538094 0.662622107831171 DCSTAMP other 1 1 1 -0.632349077740151 -0.436539982538094 1.13736363342182e-09 277.443484273038 49.8545072584882 5.56506321152739 4.1659759610015e-08 -1770.29475691474 560.234725056327 -3.15991615253187 0.00166825115555769 TP53INP1 other 9.27747515782176e-06 1 0.000434094695136356 5.56506321152739 -3.15991615253187 3.37439237522196e-60 320.43664559663 16.9551174265177 18.8991109607693 2.79523987682095e-61 428.515579763358 196.359265452165 2.1823038438069 0.0295254331661856 INTS8 essential 5.18644108071616e-56 1 4.32227942152824e-57 18.8991109607693 2.1823038438069 0.257030795634333 -2.72579836699448 11.2957536408513 -0.241311775527448 0.809405084981402 -42.0611065322548 26.1805729176901 -1.60657700900939 0.108731741814403 FREM1 other 1 1 1 -0.241311775527448 -1.60657700900939 0.00642340977097603 -46.7913865529741 14.7719736623951 -3.16757852554873 0.0016250347512602 -97.004478219172 171.332806731065 -0.56617573755992 0.571512172423645 GEM other 1 1 1 -3.16757852554873 -0.56617573755992 8.50893844169107e-16 142.020794837059 16.588963955432 8.56116121649385 1.21515334084661e-16 261.727037427314 191.690513537652 1.36536249289094 0.172718365992649 PDP1 other 9.01862385434836e-12 1 1.59889876588596e-12 8.56116121649385 1.36536249289094 9.83467703903489e-21 42.887834594992 4.42675129543273 9.68833163029538 1.51606294873079e-20 -107.327233683866 51.1524548130148 -2.09818344156102 0.0363617326059788 TMEM67 other 1.18183313978082e-16 1 2.09504738885108e-16 9.68833163029538 -2.09818344156102 6.70707365562017e-44 506.701143354506 33.0309691221253 15.3401839794976 3.12790897597142e-44 -778.568257024365 372.296746020405 -2.09125721711705 0.036979644857185 WASHC5 other 9.97811347746613e-40 1 4.75817513424773e-40 15.3401839794976 -2.09125721711705 2.52240597059142e-16 67.347076853667 13.8364555667649 4.8673648051481 1.49058501303557e-06 -199.785684636079 36.8915785406715 -5.41548213817479 9.24829608825951e-08 RPP25L other 2.71713571152108e-12 0.00122549171465527 0.0141873881540726 4.8673648051481 -5.41548213817479 2.29617422677182e-17 151.777699465165 16.994438758978 8.9310215899294 6.65082661070187e-18 59.204725452754 45.3100150429716 1.30665870220093 0.191885887460012 FAM219A other 2.54760530460334e-13 1 8.93405538615582e-14 8.9310215899294 1.30665870220093 4.88060507024571e-35 220.350809993488 23.1255084687719 9.52847416484025 5.29443453901006e-20 -282.290857436979 53.6339413915965 -5.26328757709403 2.04227723779863e-07 SNAPC3 essential 6.96511149574765e-31 0.00266455911215587 7.28037693459273e-16 9.52847416484025 -5.26328757709403 6.21511832132569e-18 52.2627633145667 12.3310414668944 4.2383089421018 2.64790432892403e-05 -206.816041959274 32.5855309774581 -6.34686732901006 4.65254282466834e-10 NUDT2 other 7.00505985996619e-14 6.56520317988949e-06 0.230473592789547 4.2383089421018 -6.34686732901006 1.07906913981888e-41 204.495320242761 13.7478843024425 14.8746756769279 3.61543683067533e-42 401.395515420136 158.263988900074 2.53624035518006 0.0114866568558845 TMEM65 other 1.59162698123285e-37 1 5.48570230318367e-38 14.8746756769279 2.53624035518006 3.2006481149162e-24 666.419631270066 64.8013077120515 10.2840460293076 8.80179881327042e-23 69.9619189182161 150.290729590671 0.465510541526832 0.641752879312985 PSIP1 og 4.08786777237097e-20 1 1.24061354273047e-18 10.2840460293076 0.465510541526832 6.73502617954153e-11 10.8416546211504 3.48983314544858 3.10663982181786 0.00199136103533922 -37.4614778184885 8.10155082932893 -4.62398849401424 4.71173051753419e-06 CCDC171 other 5.8628402892909e-07 0.0579589970961881 1 3.10663982181786 -4.62398849401424 2.60631544149615e-42 274.181680621299 25.2688332407225 10.8505872831293 5.83437889633409e-25 -429.924019684014 67.0016766166028 -6.41661584297549 3.03748587500592e-10 UBAP1 essential 3.85447990642866e-38 4.30229499335838e-06 8.35658089321932e-21 10.8505872831293 -6.41661584297549 0.970102002997734 -1.51122750194533 6.62666596448822 -0.228052464096407 0.819691462102644 -2.36527717437099 14.624251372564 -0.161736632810373 0.871573528279576 DIRAS2 other 1 1 1 -0.228052464096407 -0.161736632810373 0.187256872613167 47.4072328062097 36.2184984236898 1.30892319862719 0.191115051841399 -63.460279484566 79.9298513193971 -0.793949675084228 0.427572192006962 SYK other 1 1 1 1.30892319862719 -0.793949675084228 0.0545849067573469 8.66513858748082 4.83001721622043 1.79401815761258 0.0733614089691648 -9.14576275417373 10.2225682692983 -0.894663895925391 0.371359557246668 NIPSNAP3B other 1 1 1 1.79401815761258 -0.894663895925391 0.0142967792830112 75.3076581675629 53.7764804570567 1.40038279797243 0.161964648812632 -217.257259787114 113.688820180521 -1.91098174334241 0.0565283788017552 ABCA1 other 1 1 1 1.40038279797243 -1.91098174334241 0.0393565240099115 76.754360092748 31.3133360692494 2.45117160059234 0.0145539208293477 101.776850283578 69.2744009311919 1.46918412740472 0.14236302197949 NFIL3 other 1 1 1 2.45117160059234 1.46918412740472 1.39473031649919e-21 13.5873651137653 1.45353640102143 9.34779831053226 4.20673563978286e-19 -54.0253838096514 18.1372431235009 -2.97869877146044 0.00305124883232867 LETM2 other 1.70380255463541e-17 1 5.72620855287243e-15 9.34779831053226 -2.97869877146044 1.32642676575088e-45 198.325891689113 14.5739968080382 13.6082019435964 1.76371029645865e-36 -203.077700613834 52.8929292607114 -3.83941111699176 0.000137914762447774 METTL2B other 1.98420179888674e-41 1 2.64538907365833e-32 13.6082019435964 -3.83941111699176 1.09927672160993e-09 32.8149895906702 5.87103974745635 5.58929780792021 3.61895203033162e-08 -19.6133896648029 13.2775397391787 -1.47718553663437 0.140207781541203 FXN essential 8.97669370866666e-06 1 0.000378180487169654 5.58929780792021 -1.47718553663437 1.17106763772775e-05 21.357119303434 4.53591710359175 4.70844568268729 3.37279526872492e-06 10.0214727069761 22.3949495064506 0.447488068865239 0.654748036651262 ZMAT4 other 0.0707676173478876 1 0.0313838599754854 4.70844568268729 0.447488068865239 0.0196938383851264 9.78063165778138 3.79103578858335 2.57993651424648 0.010145422922969 47.3746643248679 35.1456677610988 1.34795174890103 0.178240131761475 TMEM71 other 1 1 1 2.57993651424648 1.34795174890103 0.132503340662949 -6.52141624772233 17.8091512493991 -0.366183438862218 0.714371087888971 -80.0637447174229 40.1339726419903 -1.99491202706547 0.0465527386724809 MAMDC2 other 1 1 1 -0.366183438862218 -1.99491202706547 0.00224020278333748 31.4532952064475 8.9706483896326 3.50624546189975 0.000492939512393465 13.7258446993302 86.7554421182927 0.158213068416097 0.874349054910372 CPA6 other 1 1 1 3.50624546189975 0.158213068416097 0.642140174553434 3.93665373848251 7.98916386820258 0.492749154157504 0.622391629127029 -57.1422203625276 77.1801525607618 -0.740374545354016 0.459396942835012 C8orf34 other 1 1 1 0.492749154157504 -0.740374545354016 0.403682862114808 15.0649200734149 66.3437659335986 0.227073634748032 0.820451948628755 -172.439678859796 145.87917148123 -1.18207196482455 0.237694529858746 ALDH1A1 other 1 1 1 0.227073634748032 -1.18207196482455 1.57762137813465e-18 193.308016797521 21.4076213405093 9.02986902294122 3.07410725160395e-18 -17.8126758839956 77.8558657718945 -0.228790415563343 0.819118918860444 KDM1B other 1.80337899734572e-14 1 4.14328175371181e-14 9.02986902294122 -0.228790415563343 2.02177129387193e-34 608.162844854434 55.4766723116416 10.9624968389968 1.49974260591871e-24 -1004.52343327713 233.830032975871 -4.29595557291303 2.20007353414917e-05 HGSNAT other 2.87273483146262e-30 0.260048691736432 2.14178241551251e-20 10.9624968389968 -4.29595557291303 1.245668289345e-08 24.6807907631684 97.1309340690951 0.254098151116424 0.799516635127923 -1247.41561784432 216.665429756109 -5.75733571917072 1.43603373658891e-08 RASEF other 9.57420647190569e-05 0.000195415470875018 1 0.254098151116424 -5.75733571917072 2.62000219115336e-07 12.3055263457955 7.41180001724685 1.66026151773675 0.0974467073624707 -75.0975885939124 16.4573015892197 -4.56317751648331 6.25244859044637e-06 GKAP1 other 0.00183609753556028 0.0763861644294833 1 1.66026151773675 -4.56317751648331 3.21440494469732e-08 10.7638241556996 5.72947455041431 1.87867562042338 0.0608302672827667 -60.6687630708196 12.6491577061208 -4.79626900702349 2.09683526075529e-06 KIF27 other 0.000240951794654511 0.0262335059473095 1 1.87867562042338 -4.79626900702349 4.51453251285104e-17 17.3940034978121 20.4372496540643 0.851093165285723 0.395096950837108 -371.574225769916 45.1200178443813 -8.23524110853577 1.3720071253388e-15 C9orf64 other 4.97140320315157e-13 2.06980994928611e-11 1 0.851093165285723 -8.23524110853577 0.0353341941433862 53.1860214734775 83.8740274826096 0.634117891673975 0.52626897325528 -384.224916992802 178.234923309698 -2.15572184091655 0.0315408241842417 SVEP1 other 1 1 1 0.634117891673975 -2.15572184091655 0.771605394228255 5.13049705632504 28.0967271739865 0.182601234106552 0.85517881899273 -61.1768499262863 99.1953845785453 -0.616730810472789 0.537669831792867 TRPV6 other 1 1 1 0.182601234106552 -0.616730810472789 5.26591568903717e-07 94.3266421140986 20.9661464213632 4.49899758488693 8.35609097237854e-06 193.304990110149 44.0732768564352 4.38599087469313 1.38719818593224e-05 ANKS6 other 0.00359767359875019 0.166089238801667 0.0757897451194733 4.49899758488693 4.38599087469313 4.66070558104748e-11 -63.480220229246 122.227547493594 -0.519360991290225 0.603721434429013 -1748.4550481247 255.90163104071 -6.83252795620729 2.25354529748365e-11 FBP1 other 4.08743879457864e-07 3.25614760033413e-07 1 -0.519360991290225 -6.83252795620729 0.121419405067088 8.22627819571351 6.4995406099184 1.2656707126593 0.206172787175556 -15.1024695455384 13.5848158072469 -1.11171691687435 0.266750954199605 TMEM246 other 1 1 1 1.2656707126593 -1.11171691687435 2.11536712941072e-26 206.26423019514 17.9562346638283 11.487053608775 1.8640828768193e-27 175.687740158466 200.792796706832 0.874970332800232 0.381981942318461 ZHX1 other 2.78551543600803e-22 1 2.70739397029235e-23 11.487053608775 0.874970332800232 0.00502023834051433 16.6280300184878 7.7152964560669 2.15520299358198 0.0315930556760175 -55.3851728350693 29.0254901766737 -1.90815633079574 0.0569079976356963 METTL27 other 1 1 1 2.15520299358198 -1.90815633079574 0.133491756542471 -3.20867542627996 4.06278061363244 -0.789773244342416 0.430033089377192 24.8414853292942 15.4410794006528 1.60879202060472 0.108290495180603 NCF1C other 1 1 1 -0.789773244342416 1.60879202060472 6.4601226724966e-09 60.1545897183135 17.719285268579 3.39486547039139 0.000736806151109085 -152.094537211285 39.327360379334 -3.86739755082085 0.000123339349122781 KIAA1958 other 5.06086010163384e-05 1 1 3.39486547039139 -3.86739755082085 0.182346661924121 0.242432280883287 10.3055573495769 0.0235244220821535 0.981240552491194 -39.7052813531294 22.8646824758275 -1.7365332492636 0.0830336189481239 RNF183 other 1 1 1 0.0235244220821535 -1.7365332492636 6.44593636384e-14 228.09610864816 41.7156806271588 5.46787455505781 6.96660087363804e-08 -425.217404037447 103.20131399797 -4.12027122102159 4.37737732097598e-05 STRBP other 6.38727834292906e-10 0.506900293769018 0.000718256550072082 5.46787455505781 -4.12027122102159 0.0522737386786105 252.220604974293 147.570576246191 1.70915240280363 0.0880070170067052 -723.344151086573 554.103155774797 -1.30543228918292 0.192311022863479 CLDN3 other 1 1 1 1.70915240280363 -1.30543228918292 2.92284205600073e-17 172.745932059416 43.1038293772351 4.00767018975467 6.99026602817332e-05 -633.636995575628 98.695088156351 -6.42014721717287 2.97679777493655e-10 GAPVD1 other 3.23558615599281e-13 4.21693172797511e-06 0.585434779859516 4.00767018975467 -6.42014721717287 8.68474231666352e-09 31.4046600276041 32.4334002608513 0.968281455999885 0.333336491388241 -382.308887490505 69.9902217050756 -5.46231856646313 7.17646971429907e-08 CARD19 other 6.74283393465755e-05 0.000954326942607491 1 0.968281455999885 -5.46231856646313 0.488775967358732 59.6716242273039 53.7035659534893 1.11112964600867 0.26700520376621 -6.34262192817219 116.266800172922 -0.0545523048603634 0.956515239265362 WNK2 other 1 1 1 1.11112964600867 -0.0545523048603634 1.1424636244135e-05 84.6367873513094 17.6726915530399 4.78912830551557 2.16462426594159e-06 40.722379710501 36.873661794656 1.10437579910772 0.269920189160889 ZNF367 other 0.069141898549505 1 0.0204145714520951 4.78912830551557 1.10437579910772 1.98447349555366e-34 189.04790333962 19.3120840405462 9.78909903989177 6.2028231924686e-21 -225.97180772247 45.989011318588 -4.91360438599243 1.18859414996604e-06 NDUFB6 essential 2.81993683718175e-30 0.0150404703736703 8.60579689723094e-17 9.78909903989177 -4.91360438599243 0.711070090678409 13.8552392130314 54.6232946213676 0.253650742033628 0.79986175744904 -89.4506004672444 138.819696999147 -0.644365334321354 0.519611663593385 AQP7 other 1 1 1 0.253650742033628 -0.644365334321354 8.6491524065984e-38 293.585562305467 26.9232426916956 10.904539459358 3.69174314262419e-25 -339.981917369715 70.2748455532628 -4.83788921474093 1.7145154194683e-06 NOL6 essential 1.2537811328605e-33 0.0215308846376829 5.29395966652309e-21 10.904539459358 -4.83788921474093 0.0588099686292929 122.110932871383 245.215913609562 0.497973117135502 0.618705724412502 -1253.83454084168 624.358917725024 -2.00819513463549 0.0451200440902267 AQP3 other 1 1 1 0.497973117135502 -2.00819513463549 5.05683692861149e-21 32.0202347630911 6.19278571693997 5.17057043900321 3.30287065329189e-07 -103.55309276551 15.4465872376498 -6.70394639102595 5.16253246361319e-11 TRMT10B other 6.11371584669129e-17 7.4139128709949e-07 0.00327677797513088 5.17057043900321 -6.70394639102595 1.41858921050263e-27 1507.82070764068 155.642944313851 9.68769072242804 1.45775874575081e-20 -1410.24899641653 409.619446929109 -3.44282725585682 0.000620567411729969 VCP essential 1.89466774954731e-23 1 2.01491413837677e-16 9.68769072242804 -3.44282725585682 3.37637059189835e-19 198.150016310854 33.3843967203386 5.93540802821027 5.26187523532324e-09 -475.977457330888 87.8769120716414 -5.41641081952048 9.18919329608005e-08 PIGO other 3.92435553896345e-15 0.00121775189559653 5.69440137966681e-05 5.93540802821027 -5.41641081952048 7.26066835869467e-25 472.418984081648 50.9540310453583 9.27147419722514 4.44052878426491e-19 -410.67711355669 134.125020840671 -3.0618978545736 0.00230951841843385 STOML2 other 9.37134465056721e-21 1 6.04355967538454e-15 9.27147419722514 -3.0618978545736 0.0311048084721795 32.4235640657831 12.4126392520561 2.61214101267079 0.0092558591940362 36.0708741995734 28.0431399270259 1.28626374555194 0.19891906356753 SLITRK5 other 1 1 1 2.61214101267079 1.28626374555194 4.11471097029754e-17 281.905360853104 31.663221092335 8.90324329388421 8.46991441542163e-18 128.099821701346 79.2602140714974 1.61619323391925 0.106643130739003 MELK other 4.53605737365601e-13 1 1.13590022225219e-13 8.90324329388421 1.61619323391925 0.0176994980251752 5.83311702497627 4.93192790997533 1.18272552467326 0.237438421199636 -43.4073464080223 19.1173489934147 -2.27057352057415 0.0235658544107069 ARMC3 other 1 1 1 1.18272552467326 -2.27057352057415 0.652062055963986 -15.6906803737385 32.6511197994801 -0.480555658430689 0.631026960083333 -109.951156930697 125.412756326233 -0.876714300455081 0.381031683403155 OTUD1 other 1 1 1 -0.480555658430689 -0.876714300455081 7.041990990358e-05 57.9883661808142 31.7724301852368 1.82511585807996 0.0685347888250076 -406.655434361534 116.156769233521 -3.50091894811567 0.000501929082340351 ARHGAP12 other 0.390548820325255 1 1 1.82511585807996 -3.50091894811567 0.550660840409791 -0.433535464684171 3.37180945451666 -0.128576501884896 0.897741443425913 -7.63388466732154 7.65189912768923 -0.997645753025873 0.318905567587653 FAT3 other 1 1 1 -0.128576501884896 -0.997645753025873 4.74107241145143e-05 22.5370858468898 35.9936045732764 0.626141396897564 0.531485310055949 -267.047424373318 68.7418825469911 -3.88478485719049 0.000115059950890312 HECTD2 other 0.268961037901639 1 1 0.626141396897564 -3.88478485719049 9.48179225034209e-12 60.1007337554971 9.00395146510067 6.67492866753532 6.22951346087133e-11 -12.864725812857 20.2815735510718 -0.634306099596357 0.526153729121905 FBXO33 other 8.60472646718544e-08 1 7.21564544172726e-07 6.67492866753532 -0.634306099596357 0.107243124945233 -0.749071277047245 3.57484364421492 -0.209539591545339 0.834108007739951 -16.8325316926159 8.15438890043039 -2.06422969251902 0.0394847630184205 LRFN5 other 1 1 1 -0.209539591545339 -2.06422969251902 1.73764811882278e-14 603.182312106028 73.7985311489539 8.17336473660396 2.23678141633187e-15 281.527979347391 193.427529688509 1.45547006571793 0.146133457671556 SPTSSA essential 1.7590211906843e-10 1 2.87851400467748e-11 8.17336473660396 1.45547006571793 1.1576153361038e-21 63.4870610496479 15.3934377441666 4.12429387800049 4.31313766179117e-05 -167.863139130521 33.0472815166086 -5.07948404307198 5.2421955025262e-07 WRN ts 1.41634236372299e-17 0.00673936653804768 0.368643875953292 4.12429387800049 -5.07948404307198 5.02821929128597e-07 -67.3007442456572 64.461698123164 -1.04404237252746 0.296932932701707 -990.313049547106 182.28757664124 -5.43269633506699 8.40952143755935e-08 MARCH8 other 0.00344191085972931 0.00111611168519288 1 -1.04404237252746 -5.43269633506699 0.579838699026688 53.0149142377652 57.02491440875 0.929679856382748 0.352962507408726 -31.8836532830226 148.622885605122 -0.214527211964749 0.830218932417238 CFL2 other 1 1 1 0.929679856382748 -0.214527211964749 1.31137951005975e-31 390.661766959233 37.8188613553139 10.3298130340019 6.60706390350336e-23 -65.6920175350405 66.469549728978 -0.988302430254037 0.323457229053627 SUGT1 essential 1.82137500152199e-27 1 9.32388858062394e-19 10.3298130340019 -0.988302430254037 4.47130158476421e-09 103.654745804903 34.8874480197559 2.97111860249011 0.00309904102230276 -273.642255803524 72.7336102140624 -3.76225317288895 0.000186774520844609 GTF2A1 essential 3.53501103291458e-05 1 1 2.97111860249011 -3.76225317288895 0.000290927188020126 4.5325806579571 31.6633147793879 0.143149278259006 0.886225785271475 -468.747886481818 118.635519093877 -3.95115973750573 8.81183272072577e-05 ZCCHC24 other 1 0.99726325601514 1 0.143149278259006 -3.95115973750573 2.92467301968007e-28 254.906831843091 22.9533586381603 11.1054262629481 6.76279026020913e-26 -102.632531118088 98.257767303285 -1.04452333830566 0.296721295448375 PGM2L1 other 3.93485508067757e-24 1 9.73436030054502e-22 11.1054262629481 -1.04452333830566 0.202865210505789 -3.45967929397589 5.14926026629895 -0.671878894259611 0.501954111717752 18.4233171426397 13.3809352066805 1.37683329737983 0.169146181071061 PHYHIPL other 1 1 1 -0.671878894259611 1.37683329737983 0.225793298826556 3.78874028675182 8.95120542727116 0.423265929660028 0.672273597694481 -33.873667366728 23.0701765741814 -1.46828817099897 0.142621430864209 SLC16A9 other 1 1 1 0.423265929660028 -1.46828817099897 0.840329690820513 7.23119690935752 16.9582166724977 0.426412579164935 0.669991124954178 25.5748680270042 47.7439957991935 0.535666686436751 0.592427594012818 FOLR2 other 1 1 1 0.426412579164935 0.535666686436751 3.12557826521295e-32 790.572049316979 71.261677291913 11.0939298562749 1.15922340658225e-25 -427.208697403958 203.659045194812 -2.09766620969526 0.03644735252082 INPPL1 other 4.36487004736989e-28 1 1.66615180228066e-21 11.0939298562749 -2.09766620969526 6.23906541322599e-06 670.175224756596 137.230958215247 4.88355713224289 1.38809418992872e-06 446.52315702054 270.010027227551 1.6537280544927 0.0987851255576516 GJB2 other 0.0385699023845631 1 0.0132382542893502 4.88355713224289 1.6537280544927 4.5674553817433e-18 44.0769392726692 19.1548299099489 2.30108747923551 0.0217798250095728 -254.852748948967 37.8124401399485 -6.73991808002143 4.20472054378673e-11 CRYL1 other 5.1616813269081e-14 6.04722908607407e-07 1 2.30108747923551 -6.73991808002143 1.51202288712304e-06 162.016568787163 51.5219226035835 3.14461418751277 0.00175629930215404 -372.803914631275 130.051106072969 -2.86659549379074 0.00431410599359462 REEP3 other 0.00992643025396278 1 1 3.14461418751277 -2.86659549379074 0.818242924971911 6.5249296434401 11.9478375520717 0.546118041444975 0.585209099826517 1.35515749831787 21.5391703359701 0.062915956240653 0.949856581212417 HEPACAM other 1 1 1 0.546118041444975 0.062915956240653 2.11352888355855e-12 110.742170357213 14.7406071886596 7.51272786391122 2.49136277991663e-13 119.706738166917 29.9549481003776 3.996225857771 7.35127250846258e-05 SKA3 essential 1.97086568391835e-08 0.837105746230241 3.07483994297311e-09 7.51272786391122 3.996225857771 2.07356445635614e-45 135.9768642631 26.7040311505601 5.0919976649386 4.94060117687689e-07 -579.788592487022 54.2892709281042 -10.6796164799273 3.10695705180966e-24 MICU2 other 3.1003935751437e-41 4.83225030267957e-20 0.0048482119348693 5.0919976649386 -10.6796164799273 5.07765847764021e-28 122.98551438941 11.0326410584162 11.1474227918972 5.25767861128134e-26 38.737192972977 26.0048509050815 1.48961411524215 0.136936680612916 DDIAS other 6.81523320868868e-24 1 7.5742118074119e-22 11.1474227918972 1.48961411524215 7.27638184296733e-17 208.753160165667 37.1302317412177 5.62218845334955 3.08886498990693e-08 -301.675805565171 86.9549317449977 -3.46933520055952 0.000565320692769794 PCF11 essential 7.96036173620626e-13 1 0.000323867494191742 5.62218845334955 -3.46933520055952 0.00704140919981311 11.910258078211 5.15195287838235 2.31179483962024 0.0211595828505981 -3.68190439671052 9.23028726447769 -0.398893803758432 0.690127127566025 PKNOX2 other 1 1 1 2.31179483962024 -0.398893803758432 1.64959186616324e-13 66.0749957767673 8.37494835453616 7.88960038672702 1.75733719191031e-14 50.2412504792354 20.7890500397835 2.41671699202656 0.0159992024355738 LRR1 essential 1.6098367021887e-09 1 2.22531608611603e-10 7.88960038672702 2.41671699202656 1.92565486201934e-25 480.30366882859 78.9055648686976 6.08706964620095 2.21309530214037e-09 -1438.7373905983 195.866489801607 -7.34550045827442 7.82425913301863e-13 RPL36AL essential 2.50412158256995e-21 1.15040082032773e-08 2.42820816550841e-05 6.08706964620095 -7.34550045827442 2.02142624976657e-21 51.5956129015595 7.34510316414947 7.02449124927084 6.67763104835299e-12 -92.8990073310626 18.2346190279305 -5.09465030164692 4.87812738570885e-07 DNAAF2 other 2.46149074434076e-17 0.00627912557088443 7.95840068342709e-08 7.02449124927084 -5.09465030164692 0.287375718997205 192.022404379952 151.583976968955 1.26677244006653 0.20578479749984 -236.037151192435 432.904528636413 -0.545240660650788 0.585813972400855 C10orf10 other 1 1 1 1.26677244006653 -0.545240660650788 3.65258344428764e-05 70.2119089868546 28.1833355887527 2.49125618100628 0.0130289024448257 -238.187189553141 80.6778278110453 -2.95232526724687 0.0032913352683084 ZNF22 other 0.210060073880982 1 1 2.49125618100628 -2.95232526724687 8.93130717264962e-39 193.799910367628 33.1518532689414 5.84582432829453 8.79034034060876e-09 -895.671402381334 81.7605788241948 -10.9548075033476 2.51042966405351e-25 KLHDC2 other 1.30075557662469e-34 3.90999420176335e-21 9.42939808337101e-05 5.84582432829453 -10.9548075033476 3.08436822981683e-22 17.9158978252833 11.4227727004122 1.56843686687705 0.117361739922386 -201.036446784474 23.0329101607632 -8.72822606354543 3.18647101949116e-17 EML5 other 3.8172141212213e-18 4.85522589239868e-13 1 1.56843686687705 -8.72822606354543 6.26714250425059e-33 206.938419284962 28.0322214682864 7.38216268443359 6.02576512788098e-13 -569.470992360555 69.1479997867954 -8.23553818066191 1.38844631005565e-15 NEMF other 8.80972221822505e-29 2.09447125871895e-11 7.35926695068104e-09 7.38216268443359 -8.23553818066191 3.30781347472175e-40 106.970964867804 13.1149967685747 8.15638514865066 2.4003039340421e-15 -139.785658745254 24.3944004812805 -5.73023546336059 1.66238348702465e-08 RPUSD4 essential 4.84925455394208e-36 0.000225685182198467 3.08703088957155e-11 8.15638514865066 -5.73023546336059 9.60037520322675e-17 636.331647841662 107.953741723087 5.89448441235064 6.64516983419008e-09 -1285.9207325803 271.430971050061 -4.73756081557523 2.77275459689218e-06 ARF6 other 1.04653690090375e-12 0.0345069309583232 7.16548663220716e-05 5.89448441235064 -4.73756081557523 6.69761610587628e-35 34.3068779100623 22.4519374850134 1.52801413833269 0.127091309091164 -527.10429431928 45.3126208620093 -11.6326154676524 4.41859837032456e-28 TTC8 other 9.54678199731605e-31 6.90405995363212e-24 1 1.52801413833269 -11.6326154676524 5.73284217562591e-19 7.75303379737477 43.9985279030061 0.176211209031043 0.860193591785646 -791.35990079377 92.5138409546701 -8.55396222476073 1.21336725118607e-16 TMEM63C other 6.6202861444128e-15 1.84189148730045e-12 1 0.176211209031043 -8.55396222476073 1.72116435462612e-17 0.563345140678268 0.707519939278181 0.796225108868307 0.426248525261665 -11.6943907853702 1.48475570500624 -7.87630634853904 1.84264687835885e-14 NOXRED1 other 1.91513957739248e-13 2.7538357597073e-10 1 0.796225108868307 -7.87630634853904 0.416822418843458 1.11585658348609 5.09756358487037 0.218899983277888 0.826809609713753 13.7346804135027 10.9443768718386 1.25495316675762 0.210031660530429 AMER2 other 1 1 1 0.218899983277888 1.25495316675762 6.71844780397897e-29 42.739789136297 3.57522548840334 11.9544317623961 2.19110513964543e-29 58.7502878270802 15.5985792940792 3.76638709971364 0.000183823282565798 AKR1E2 other 9.1048404639523e-25 1 3.2115028031783e-25 11.9544317623961 3.76638709971364 1.45341392308788e-19 96.8352499226255 14.9214794991394 6.48965472413178 1.93832324505615e-10 -76.9904385785045 28.192014634627 -2.7309307112781 0.00652048446486561 KBTBD6 other 1.70601726292056e-15 1 2.21201448725808e-06 6.48965472413178 -2.7309307112781 9.76481284495241e-60 504.159326506435 26.8973043078663 18.74386075035 9.89713683034111e-61 81.5595756278224 155.67163151471 0.52392060669137 0.600549119620882 NUDT5 other 1.49958230859934e-55 1 1.52989941123413e-56 18.74386075035 0.52392060669137 2.45518822134983e-05 -10.7212907480384 21.4632177053913 -0.499519265713145 0.617614840607458 -203.777486439723 45.3831083827209 -4.49016150945952 8.68799048943421e-06 DACT1 other 0.143603959066752 0.105310549886474 1 -0.499519265713145 -4.49016150945952 7.61990812587555e-09 20.6698045596375 3.76251241578752 5.49361763509586 6.1028034662279e-08 44.783689677514 9.74670481767727 4.59475181769035 5.4116263915462e-06 OXGR1 other 5.9390891827969e-05 0.0663898325714888 0.000631151934477289 5.49361763509586 4.59475181769035 7.05459516960066e-11 83.6703494182703 12.000604575508 6.9721778508587 9.09420445347405e-12 87.5774023866231 66.0809326797693 1.32530518010432 0.185627306485352 BEND7 other 6.13397049996778e-07 1 1.08048243111725e-07 6.9721778508587 1.32530518010432 1.77133476529169e-36 1030.67135241103 75.1713217457991 13.7109648796168 6.17656433168164e-37 23.1128115244072 321.989312386836 0.0717813002955812 0.942802482738243 ATP5C1 essential 2.54895072725474e-32 1 9.27102306185414e-33 13.7109648796168 0.0717813002955812 8.34959303954261e-77 159.249385475012 7.21212246603505 22.080793306684 1.51778829513462e-77 22.0658748335704 39.103248954329 0.564297735447569 0.572784958522868 PRPF18 other 1.29652480718018e-72 1 2.36183036605899e-73 22.080793306684 0.564297735447569 0.000237122335446061 38.9977086907586 10.9116981568008 3.57393580085909 0.000383088777249084 -68.1209874411835 46.7392365184446 -1.45746898142637 0.145567169568731 TAF3 other 1 1 1 3.57393580085909 -1.45746898142637 0.00635180187800527 -54.9468047307028 22.2032563500482 -2.47471829647111 0.0136362022313464 -157.178467110638 58.440646104701 -2.68954020167813 0.00737348403413075 VSTM4 other 1 1 1 -2.47471829647111 -2.68954020167813 7.73819894399971e-24 234.787311469607 25.009775430869 9.38782165871887 1.80729529614678e-19 -146.541897017867 64.705230200662 -2.26476123434559 0.0239311037895723 VDAC2 other 9.82364355940763e-20 1 2.47183777653994e-15 9.38782165871887 -2.26476123434559 0.000166335427885732 60.3929781898159 18.8804148622816 3.19871033715823 0.00146311563785873 -76.286270272473 48.1197793147436 -1.58534123304051 0.113486392681068 COMTD1 other 0.877918388380894 1 1 3.19871033715823 -1.58534123304051 0.220038618288285 -38.2388800515401 43.5757313349321 -0.877526983027046 0.380589273538836 -144.372971713597 83.7151745444158 -1.72457350174906 0.0851744867539232 SLC18A2 other 1 1 1 -0.877526983027046 -1.72457350174906 0.021215386131654 47.0248849805611 57.8088443724742 0.813454852644522 0.416314519764542 -240.496726737688 111.059008044074 -2.16548599679771 0.0307859728770752 PDZD8 other 1 1 1 0.813454852644522 -2.16548599679771 2.19559432185475e-05 90.4066844609569 19.3283959161816 4.6774023490107 3.69040581790507e-06 83.4171282794555 64.5965519903872 1.29135574127655 0.197142201636007 ZNF503 other 0.129100946125059 1 0.0342691084250664 4.6774023490107 1.29135574127655 3.13569778439151e-13 121.798565745598 15.6609695917245 7.77720466362171 4.01002130413504e-14 114.320972246597 36.1202422459971 3.16501122744453 0.00164159066128887 QSOX2 other 3.02563479215937e-09 1 5.04059677929775e-10 7.77720466362171 3.16501122744453 3.24009442461309e-27 69.1816102694519 24.1711206801678 2.86215981397234 0.00437058706413473 -425.651996876859 45.1662848612459 -9.42410911556025 1.25523549596422e-19 FAM204A other 4.3102976130628e-23 1.93092876344176e-15 1 2.86215981397234 -9.42410911556025 1.15013644485218e-08 273.37469358337 66.8660223808939 4.08839473097601 5.00736689818433e-05 -555.484294607147 191.326842090177 -2.90332651988964 0.0038437511443314 NSD1 other 8.86180130758606e-05 1 0.425075375986868 4.08839473097601 -2.90332651988964 2.61552288146469e-22 681.115456783899 116.708266383483 5.83605153165304 9.21597724778586e-09 -1250.09788137077 216.860909526169 -5.76451461031945 1.37707867747657e-08 PRDX3 other 3.24141750699919e-18 0.000187530574298759 9.87676281645211e-05 5.83605153165304 -5.76451461031945 8.49722269429623e-23 848.598886698892 98.0091542136797 8.65836353254081 5.49054967712571e-17 -760.675694138565 231.301708182507 -3.28867305008555 0.00107192380798033 GHITM other 1.06181294787926e-18 1 7.27278210232071e-13 8.65836353254081 -3.28867305008555 3.67695483084926e-14 85.3831923045747 14.7903592416856 5.77289509398313 1.34231193250503e-08 -118.225346011831 34.1159691454374 -3.46539608790922 0.000573300450343701 SNAPC4 essential 3.67732252633235e-10 1 0.000142996490169761 5.77289509398313 -3.46539608790922 0.0780078036861299 3.57406613249718 1.5791188571628 2.26332939809148 0.0240078820720721 4.00402672893375 5.33619122504015 0.750352931533787 0.453365985806017 TMEM52B other 1 1 1 2.26332939809148 0.750352931533787 1.35693065198528e-14 246.532090337668 36.5365124190472 6.74755399503174 4.02772793720073e-11 -188.673720668868 84.509031391409 -2.23258647700047 0.0260019907769711 PMPCA essential 1.37891292854744e-10 1 4.69109472845769e-07 6.74755399503174 -2.23258647700047 1.34780297241082e-17 179.814511936461 20.7075356778857 8.68353022462691 4.99702091931282e-17 6.23460244364852 47.7647389573671 0.130527300677039 0.896199832179942 SDCCAG3 other 1.50482201869668e-13 1 6.624550632733e-13 8.68353022462691 0.130527300677039 1.51479835434918e-21 19.5805155050084 6.11788523760173 3.20053658160547 0.00145129857869812 -112.733915174408 14.0588101809185 -8.01873798164064 6.51939037881808e-15 AK8 other 1.84911435115404e-17 9.78364914149229e-11 1 3.20053658160547 -8.01873798164064 7.10304724418064e-22 33.2289200951694 8.21665497081551 4.04409339484185 6.00752454772884e-05 -141.936894599056 18.881752120293 -7.51714637999673 2.30416689057371e-13 SPACA9 other 8.73390689144452e-18 3.40786283115851e-09 0.506554469864496 4.04409339484185 -7.51714637999673 2.85818783456489e-26 97.8546312455886 22.4039274101886 4.36774452326994 1.50201923932262e-05 -431.044780126544 51.4987190326186 -8.37000974438851 4.83915382526845e-16 TSC1 ts 3.75765954610246e-22 7.318736245336e-12 0.133364288259455 4.36774452326994 -8.37000974438851 3.22766397902809e-19 52.7842513812866 7.57638013645334 6.96694865234098 9.42730348584205e-12 -98.5442819175248 24.781299486296 -3.9765582903358 7.94055166754762e-05 BORCS5 other 3.75474150680338e-15 0.901729047366707 1.11949228894374e-07 6.96694865234098 -3.9765582903358 1.80913693978301e-05 42.3129275300036 11.200346751673 3.77782299674637 0.000176680427270553 -37.4579050084311 25.9739997349478 -1.44213079967163 0.149873320163935 FAM69B other 0.107498916961906 1 1 3.77782299674637 -1.44213079967163 1.44238200784635e-09 126.978986550898 19.8520056449697 6.39627999416138 3.69071233005287e-10 40.2779007259716 46.2788839226794 0.870329993118807 0.384541950816772 ZMYND19 other 1.17150266677281e-05 1 4.17862450008586e-06 6.39627999416138 0.870329993118807 0.000418844468006767 -9.74579321907455 13.8165526050233 -0.705370832919007 0.480882519810361 -134.767312154349 34.2952438225017 -3.92962105334052 9.60893081237259e-05 STOX1 other 1 1 1 -0.705370832919007 -3.92962105334052 0.421510870139841 111.113616735437 174.47659516102 0.636839666849835 0.524509533089688 -469.353756837158 502.816214144949 -0.933449923915651 0.351020937931349 RET other 1 1 1 0.636839666849835 -0.933449923915651 2.48028101792749e-10 650.020645046638 100.307946760235 6.48025072829351 2.05384959298844e-10 5.3347745628307 270.873432135494 0.019694713212635 0.984294129501322 DDX21 essential 2.10054999408279e-06 1 2.34179930592542e-06 6.48025072829351 0.019694713212635 3.23866102456733e-20 283.015172881851 31.6021101553111 8.95557832976817 6.16650114814042e-18 -148.663276659363 91.8753784121737 -1.61809702695782 0.106253942835206 BMS1 essential 3.85076795821056e-16 1 8.28469429252665e-14 8.95557832976817 -1.61809702695782 1.10138017172073e-14 84.4438435584914 14.5353334579247 5.80955667807213 1.07820102279698e-08 -89.5789321436006 28.9126920534513 -3.09825636360651 0.00204927305754798 STK32C other 1.12274694705211e-10 1 0.000115259689336997 5.80955667807213 -3.09825636360651 4.20367560266464e-27 116.877414000994 13.6905431252111 8.53709110968467 1.36418945780332e-16 -179.127684830633 38.3029332611339 -4.67660488582984 3.6790491364461e-06 METTL17 essential 5.58626450838104e-23 0.0454693682773374 1.79349988017402e-12 8.53709110968467 -4.67660488582984 0.959549767018699 0.96830205753804 3.87289700506806 0.250020089940663 0.802665681486274 2.3445843700016 10.8354587656346 0.216380720070442 0.828771663757999 SLC39A2 other 1 1 1 0.250020089940663 0.216380720070442 2.1089849566639e-07 -65.6106053390271 35.9423526565522 -1.82543991947245 0.0684889081070655 -546.348108525111 97.1495820161815 -5.62378238986257 3.00575531044734e-08 ARHGEF40 other 0.00149041966887438 0.000404694894998629 1 -1.82543991947245 -5.62378238986257 4.0958443931386e-09 -4.09061890194393 23.2660463324239 -0.175819253666798 0.860501976441304 -387.159449773708 64.3661180998981 -6.01495726638082 3.32272121653896e-09 ZNF219 other 3.24522704189344e-05 4.59864616368992e-05 1 -0.175819253666798 -6.01495726638082 7.76743670319767e-07 92.4682740066313 44.6171104513295 2.07248459327056 0.0386889708625988 -320.218823011286 85.0374944097404 -3.76561921578215 0.000184167160664261 CASP7 other 0.00524146628731779 1 1 2.07248459327056 -3.76561921578215 3.14561968591444e-06 6.65737910893089 3.70485627110204 1.79693316603362 0.0729038738689583 -26.5577937830501 7.36876671571429 -3.60410293983308 0.000342158509366674 PPP1R36 other 0.0200533254977046 1 1 1.79693316603362 -3.60410293983308 9.31130164135989e-05 109.535193581144 33.0875596599252 3.31046455849115 0.000996438409541091 -136.438089129509 87.3366749867971 -1.56220842103428 0.118850778544721 BTNL9 other 0.508024617552596 1 1 3.31046455849115 -1.56220842103428 3.82404097490408e-10 -43.5676549262165 38.2268523231337 -1.13971337629205 0.254909150404592 -485.323780186912 74.2241475606231 -6.53862383250034 1.43647477383838e-10 VWA2 other 3.20225191238467e-06 2.04726384767445e-06 1 -1.13971337629205 -6.53862383250034 2.35729549112552e-24 140.377905574744 20.5461762770608 6.83231291709844 2.22968470847168e-11 -332.857284348514 57.2823138987499 -5.8108212062952 1.05536507781543e-08 METTL3 essential 3.01686676954244e-20 0.000144152315978809 2.61876469009999e-07 6.83231291709844 -5.8108212062952 4.27274308186633e-17 40.2522012177681 27.6734920596516 1.4545400027941 0.146369168156895 -607.723321535793 77.1531226764251 -7.87684672316561 1.81443215596052e-14 SALL2 other 4.70899015052488e-13 2.71203174351419e-10 1 1.4545400027941 -7.87684672316561 1.69079356837366e-10 131.778851041176 27.7190606442566 4.75408790840393 2.55912759878818e-06 -145.157908750123 53.8774235687176 -2.6942251342992 0.00727441465990549 TRUB1 other 1.44427586610478e-06 1 0.0240353264078186 4.75408790840393 -2.6942251342992 1.06252435035302e-32 4.7222441102326 1.1820370064216 3.99500530404571 7.36157201408892e-05 -19.4205033411941 2.25787510756802 -8.60123010174469 8.48366096332197e-17 ERICH6B other 1.4901904013701e-28 1.28917711998641e-12 0.615795498978538 3.99500530404571 -8.60123010174469 2.48109195457713e-42 38.1619664422811 17.5398073358311 2.17573464243943 0.0300056072823607 -430.979781520657 34.3558969943599 -12.5445649575504 7.05054090555478e-32 ZFYVE1 other 3.67027932840594e-38 1.10404420040082e-27 1 2.17573464243943 -12.5445649575504 0.38435917358912 9.44859078429507 19.8797948468872 0.475286131324165 0.634774519341155 -39.1907332522987 37.8359934208207 -1.03580558375751 0.3007547598116 C10orf82 other 1 1 1 0.475286131324165 -1.03580558375751 0.000326481145409131 72.8550467930973 29.1961763374055 2.49536261019759 0.0128791565348063 -113.33284751658 55.5672905240352 -2.03956044010385 0.0418785395631583 HSPA12A other 1 1 1 2.49536261019759 -2.03956044010385 1.09073433541061e-21 5.84219324834477 7.74179213726314 0.754630600352193 0.450795417040498 -135.717179048383 14.964304366298 -9.06939445538413 2.13852633523739e-18 FRAT1 other 1.33582234057737e-17 3.27536693504959e-14 1 0.754630600352193 -9.06939445538413 2.73981585033871e-07 19.6917245920002 14.9090834111701 1.32078706979712 0.187124666448919 -127.837471089438 28.9596500721884 -4.41433065561134 1.22122424747804e-05 UBTD1 other 0.001917049150482 0.146656819879637 1 1.32078706979712 -4.41433065561134 3.77256191052994e-07 33.076853654014 9.97271148485607 3.31673624612949 0.000973680569961775 155.457480361174 31.1061045024875 4.99765183868466 7.91444042655996e-07 E2F7 other 0.00261325363542409 0.0100996174283332 1 3.31673624612949 4.99765183868466 2.5709606213312e-05 6.81423876053177 15.237244612764 0.447209382910581 0.654902546086605 -110.801630424723 30.8904498146273 -3.58692188328886 0.000364879283073466 ARHGAP42 other 0.150195519498168 1 1 0.447209382910581 -3.58692188328886 4.99284643178267e-50 105.275164206306 10.5817658534286 9.94873310036398 1.54771879540535e-21 -163.596283804922 20.9935270647308 -7.79270121216383 3.35034574077753e-14 ISCA2 essential 7.55068165878493e-46 4.99369032662891e-10 2.1576747726746e-17 9.94873310036398 -7.79270121216383 0.373414709338592 -5.81903554402013 6.34004932309956 -0.917821809811297 0.359128066939576 -27.5906451245076 22.3720643657476 -1.23326326410672 0.218022186522345 OTOGL other 1 1 1 -0.917821809811297 -1.23326326410672 2.76224164468279e-06 214.678128686037 42.0542789766934 5.10478681146839 4.63835311973034e-07 151.600307949732 119.693881523963 1.26656689564688 0.205871832502161 LARGE2 other 0.0177004444591273 1 0.00456042878731887 5.10478681146839 1.26656689564688 8.71449462690789e-08 213.648307322758 48.8480045598967 4.37373663975947 1.46606224626177e-05 -290.830024964089 142.911778781012 -2.03503187382292 0.0423355314061113 PACSIN3 other 0.000632672309913513 1 0.130288951825284 4.37373663975947 -2.03503187382292 8.26121351975345e-05 54.1609974719298 12.4655994674377 4.34483697421915 1.66442406881877e-05 55.7309725134368 25.3589860659116 2.19768142025017 0.0283940578259972 TTC7B other 0.45436674358644 1 0.147251369495364 4.34483697421915 2.19768142025017 1.04062080030557e-07 72.1615929670591 26.4573100864656 2.72747277524536 0.00659058731961753 -291.489876310965 74.8670912935778 -3.8934312963748 0.000111260244405804 SLC39A13 other 0.000751848528220777 1 1 2.72747277524536 -3.8934312963748 7.96478553255354e-22 582.55341674264 64.4703598104632 9.0359882968746 2.89992970963682e-18 -308.183284536523 181.759544196758 -1.69555489313348 0.0905477054781316 PSMC3 essential 9.78075663397575e-18 1 3.90997522750333e-14 9.0359882968746 -1.69555489313348 9.02545616379185e-06 0.816946405377059 2.56100473246436 0.318994492677466 0.749855896572976 -32.8296769323189 7.34209930329288 -4.47142916162888 9.50329347549528e-06 AGBL2 other 0.0551274862484406 0.114894818118738 1 0.318994492677466 -4.47142916162888 7.48356723727036e-14 480.879891567983 193.402856033241 2.48641566847044 0.0132015182474248 -2359.15725459128 394.598005595984 -5.97863451192083 4.06734952212274e-09 TC2N other 7.39750621404176e-10 5.61904336481256e-05 1 2.48641566847044 -5.97863451192083 2.30752461077929e-22 341.3111162195 43.0125039236232 7.93516036233468 1.19541747537796e-14 -267.834829157226 87.7020982120587 -3.05391586538347 0.00236869146684132 CPSF2 essential 2.86225352721063e-18 1 1.51901698596277e-10 7.93516036233468 -3.05391586538347 1.00393164743316e-32 28.3139649558897 31.0864765449616 0.910812935487819 0.362795867074277 -720.790324547543 62.7856900740319 -11.4801688680597 1.77577257145175e-27 MOAP1 other 1.40851610134872e-28 2.77340160209334e-23 1 0.910812935487819 -11.4801688680597 0.00107103884106588 15.1233401510151 8.38968499661164 1.80261120138873 0.0720006029780313 -39.0761979575468 17.3848120485054 -2.24772047281962 0.0249923508050344 IFI27L1 other 1 1 1 1.80261120138873 -2.24772047281962 0.00131591217647585 2786.54858805341 760.407816752485 3.66454490164774 0.000271957122239274 2327.50844731317 1575.69050325433 1.47713554311972 0.140215849313748 IFI27 other 1 1 1 3.66454490164774 1.47713554311972 3.0508745379954e-11 72.1478106693296 79.8029541868025 0.904074434393071 0.366354646351208 -1007.05415630248 165.184442726691 -6.09654359502074 2.05094349988976e-09 CLMN other 2.70124431594112e-07 2.85306750269665e-05 1 0.904074434393071 -6.09654359502074 0.348351712113286 19.6320849290709 20.6426334956645 0.951045559821336 0.342018864920078 -58.2973476373397 66.6184964468052 -0.875092515543187 0.381923732397258 PDZRN4 other 1 1 1 0.951045559821336 -0.875092515543187 0.461539231016344 -20.01399062684 21.625431964184 -0.925483969984376 0.355126096425146 -64.0657930943383 58.2550572564753 -1.09974646170684 0.271930827357867 NELL1 other 1 1 1 -0.925483969984376 -1.09974646170684 5.03984716919307e-05 48.2929608986018 15.2199851885484 3.17299657656288 0.00159362986175292 -154.209949628522 60.7067247075694 -2.54024492955875 0.0113534081223117 PTER other 0.284700966587716 1 1 3.17299657656288 -2.54024492955875 0.455087622156211 -0.451873159595151 1.23196341527534 -0.366791054013692 0.713916982836931 -6.13166755283086 4.91383289631507 -1.24783802831982 0.212625264030196 C1QL3 other 1 1 1 -0.366791054013692 -1.24783802831982 0.553896356336383 -17.0911376699311 20.5240194427086 -0.832738329723371 0.405358428031566 -65.810294149928 80.4586009510589 -0.817939827091437 0.413750317245497 CACNB2 other 1 1 1 -0.832738329723371 -0.817939827091437 2.80290394647609e-11 37.7533220370576 5.41447023187288 6.97267145635384 9.01472756375405e-12 57.4702021259208 23.6948376864255 2.42543134865384 0.0156133758501166 HACD1 other 2.48589551012964e-07 1 1.07131022367653e-07 6.97267145635384 2.42543134865384 1.45836142252034e-17 290.08317869646 32.0507343684753 9.05074983185979 2.57899406171975e-18 376.365370267631 124.21671800133 3.02990914848999 0.00256362933512196 ARL5B other 1.62723967524819e-13 1 3.47957878807229e-14 9.05074983185979 3.02990914848999 3.01385463285775e-14 107.083863434273 16.0694378899379 6.66382135876231 6.65833606679907e-11 -13.1178910986319 35.2746418224923 -0.371878789433022 0.710130617882482 SMCO4 other 3.0234989676829e-10 1 7.70635816371325e-07 6.66382135876231 -0.371878789433022 2.09656090065713e-34 186.737869863512 17.7991321479222 10.4914030814312 1.50985645029738e-23 -57.3345211308853 39.1662204765161 -1.46387679059466 0.143813817580325 CEP295 other 2.97837441547353e-30 1 2.14173137474683e-19 10.4914030814312 -1.46387679059466 0.101433659002778 176.972811625981 109.083663694389 1.62235852402053 0.105325782625681 -348.197906270934 338.863400375469 -1.02754651545467 0.304635476937892 KCNC2 other 1 1 1 1.62235852402053 -1.02754651545467 1.1878382215418e-17 166.739155657761 18.7275006181734 8.90343880143599 8.41737492199882e-18 264.119594074822 64.2425221167133 4.11128930453539 4.5530402910088e-05 ABTB2 other 1.32835948315019e-13 0.526923352878448 1.12893832453848e-13 8.90343880143599 4.11128930453539 1.39677512405106e-14 46.9524831603838 10.0977061272188 4.64981675727533 4.16987770388335e-06 -82.9499966917269 19.4341411814371 -4.26826150521938 2.32220071978726e-05 R3HCC1L other 1.41856481598626e-10 0.273764242855721 0.0385630290055132 4.64981675727533 -4.26826150521938 4.54003913481169e-06 263.668927336273 65.7349522269278 4.01109179217237 6.90255884422164e-05 -41.7662830258533 133.587137813529 -0.31265197914603 0.754666685801499 AMOTL1 other 0.0284660453752693 1 0.578848584676427 4.01109179217237 -0.31265197914603 0.000127309685155242 -229.852455333423 171.348958115071 -1.34142896380534 0.180341971840138 -2677.1549175964 629.484025931781 -4.2529354317349 2.48445063422081e-05 HTRA1 other 0.684034938339118 0.292370150635105 1 -1.34142896380534 -4.2529354317349 1.58798203374239e-17 141.54179281915 29.7206371682944 4.76240775114152 2.46551697299077e-06 -218.489248460622 58.377941862997 -3.74266788941238 0.000201741659262548 CEP57 other 1.76964717840252e-13 1 0.0231832560970322 4.76240775114152 -3.74266788941238 3.19485443298777e-05 5.49126835254696 6.76859364680516 0.811286456107303 0.417556648839332 -66.5422878385282 16.3803731763093 -4.06231818544692 5.57530935081672e-05 TCP11L2 other 0.184790380404013 0.64093756296989 1 0.811286456107303 -4.06231818544692 0.0272450793392468 -102.624804172608 68.5822195189728 -1.49637624580257 0.1351409333844 -312.817324172864 116.266860587288 -2.6905114887661 0.00735559774973591 SPRED1 other 1 1 1 -1.49637624580257 -2.6905114887661 0.0575617987236267 -23.6110027682077 14.536221300893 -1.62428751457968 0.104895828448478 19.4110070410383 25.3519237858148 0.765662093537034 0.444210678360791 GPR176 other 1 1 1 -1.62428751457968 0.765662093537034 0.0930254088439703 -68.6599641874268 36.3699112584691 -1.88782325311389 0.0596019548604277 -131.056008024718 65.2508309671425 -2.0084956173311 0.045103231030723 JAM3 other 1 1 1 -1.88782325311389 -2.0084956173311 0.0840664473875484 2.59984097956049 2.00927500871974 1.29391993046141 0.196277582613808 -2.50488752001752 3.60297260759624 -0.695228022199338 0.487228431056037 GLB1L3 other 1 1 1 1.29391993046141 -0.695228022199338 0.057981653425062 -125.874666281037 183.744069008175 -0.685054309292762 0.493604139871773 -797.06928371021 351.004145732716 -2.27082583895509 0.0235511927453478 ADAMTS15 other 1 1 1 -0.685054309292762 -2.27082583895509 6.51397435007576e-12 252.413343583005 57.4725976634007 4.39189028937429 1.38244238010383e-05 -380.417202196965 152.307441737 -2.49769281040028 0.0128327421973622 GPT2 other 5.9583323380143e-08 1 0.123175616067252 4.39189028937429 -2.49769281040028 1.35428003833629e-36 74.8155051465785 11.966038607937 6.25232022040728 8.23287319063242e-10 -228.221741858249 25.2761390452156 -9.02913777495809 3.06200695036943e-18 AMN other 1.94962154318893e-32 4.68640163754041e-14 9.19447277929829e-06 6.25232022040728 -9.02913777495809 0.00148615543664113 55.0256535936608 21.68210423268 2.53783733364423 0.0114339613135122 -84.7409219311051 47.8568132716192 -1.77071802608636 0.0771716880057275 RAB8B other 1 1 1 2.53783733364423 -1.77071802608636 0.0273572321284322 23.3919442525259 10.1727777997056 2.29946477875521 0.02185996328984 -16.1143550591449 24.784653520881 -0.650174715800185 0.51585638669325 IKBIP other 1 1 1 2.29946477875521 -0.650174715800185 2.76865297118693e-16 43.0406676696168 7.10287039736016 6.05961607938294 2.54726271054952e-09 -33.3356041519524 12.5481732576787 -2.65661012702014 0.00812438826943691 RPUSD2 other 2.9785168664029e-12 1 2.78797903669645e-05 6.05961607938294 -2.65661012702014 1.31792281603214e-27 172.319908512357 43.4423819886836 3.96663121642926 8.26120436602089e-05 -726.035689433489 84.8477822408536 -8.55692005446323 1.17699104664723e-16 HIF1AN other 1.76100846678214e-23 1.78679010791516e-12 0.687993099602219 3.96663121642926 -8.55692005446323 2.89547737918824e-13 163.893500366869 39.9720940245953 4.10019800979212 4.75501641890308e-05 -356.687804639919 78.6294431017171 -4.53631350508866 7.04084238704424e-06 NDUFB8 essential 2.7978997915096e-09 0.0858137870132953 0.404604347084463 4.10019800979212 -4.53631350508866 9.38354315620148e-23 183.599584287313 32.6314716822031 5.62645736837689 2.947129833184e-08 -300.649996769597 57.3294090270774 -5.24425424702348 2.25049824742516e-07 ZFYVE19 other 1.17200454020956e-18 0.00293149901709601 0.000309389689887656 5.62645736837689 -5.24425424702348 3.48669685188493e-16 1206.72313211952 200.231258151355 6.0266471042566 3.08845031168850e-09 -961.062321570625 351.781243897314 -2.73198852480936 0.00649987373643894 SPINT1 other 3.73948237364659e-12 1 3.37042582514566e-05 6.0266471042566 -2.73198852480936 0.0457111378771766 -1052.02467938749 573.137874180199 -1.83555253767215 0.0669787360532853 -2343.85265621317 1002.7816192748 -2.33735103552079 0.0197887945623236 FBN1 other 1 1 1 -1.83555253767215 -2.33735103552079 0.288993576678852 -3.66918291083558 8.68170881361897 -0.422633722186091 0.67273360615744 35.9131117754132 26.0501573712575 1.37861400465235 0.168594300598279 AVPR1A other 1 1 1 -0.422633722186091 1.37861400465235 1.7018603884781e-11 2.62107266427369 0.596984996907631 4.39051681005517 1.3614251559098e-05 -6.19394244349842 1.47715894356463 -4.19314554502267 3.21583918409028e-05 DEPDC4 other 1.52384579184329e-07 0.375384907958858 0.121439123907154 4.39051681005517 -4.19314554502267 0.864414084004489 -2.68894053605499 6.9057592027731 -0.389376527199965 0.697152864003655 -12.4457459543561 27.2732777015114 -0.456334808399887 0.648334776201629 LRTM2 other 1 1 1 -0.389376527199965 -0.456334808399887 1.75529323894296e-40 169.972181984311 27.3625376167336 6.21185740756603 1.08775180806693e-09 -545.983420420288 70.7035988102404 -7.72214469429822 6.09463962150766e-14 BRD7 other 2.57554176950101e-36 9.06943322076556e-10 1.20903613466639e-05 6.21185740756603 -7.72214469429822 0.179380108006826 314.986501995997 169.650496055618 1.85667893297956 0.0638972174722224 256.546655455818 351.609060142897 0.729636077499127 0.465926708648803 CKB other 1 1 1 1.85667893297956 0.729636077499127 1.68881762106028e-06 95.6115758984074 18.8049966833232 5.08437079296049 5.0824119693615e-07 36.7485270201487 38.9742875119322 0.942891566879778 0.346154911791277 TRMT61A other 0.0110516225122184 1 0.00498280132001039 5.08437079296049 0.942891566879778 3.54089355265845e-15 -2.21821920014303 70.0776213770856 -0.0316537456116962 0.974759749289835 -1034.28021393973 134.324315758246 -7.69987331110776 6.43524523425358e-14 BTRC other 3.6772179544358e-11 9.57371433499905e-10 1 -0.0316537456116962 -7.69987331110776 2.64219024966013e-27 37.0503398724946 19.0879502434404 1.9410329239111 0.0527694679829822 -358.359684199529 36.6973983035885 -9.76526132002349 7.24500107383615e-21 POLL other 3.51807631742247e-23 1.11899041585399e-16 1 1.9410329239111 -9.76526132002349 8.91062237848361e-22 253.26039897667 33.3626180238681 7.59114284123278 1.38759040916127e-13 -232.560442319327 69.1456791463375 -3.36334019985752 0.000824265136285848 BAG5 other 1.09315515339237e-17 1 1.72199969776913e-09 7.59114284123278 -3.36334019985752 7.23207668456189e-20 89.4152044368572 19.7152693933507 4.53532755007719 7.07785424750761e-06 -230.208441702342 37.9034461198353 -6.07354911673509 2.34855250029201e-09 DPCD other 8.54180577213604e-16 3.26237427815564e-05 0.0644792521947943 4.53532755007719 -6.07354911673509 2.32025383160294e-13 111.723194020681 14.8672695581305 7.51470830496797 2.40185873905139e-13 137.389156319871 32.0783739007972 4.28292147054428 2.18557644445647e-05 LARP6 other 2.25111026742117e-09 0.258378847263643 2.96557498510675e-09 7.51470830496797 4.28292147054428 2.03217287316193e-18 340.821537758338 61.6691640588718 5.52661192931003 5.14471720426041e-08 -833.194127741012 161.764404396936 -5.1506642072908 3.67571474156968e-07 API5 other 2.31891246556508e-14 0.00475306673232375 0.000534073092974273 5.52661192931003 -5.1506642072908 1.28120126110532e-27 44.7650602565782 6.81378658764312 6.56977727153359 1.18034805245636e-10 -57.656298010305 14.8136198759435 -3.89211404728533 0.000111706255730008 ZNF319 other 1.71219736534115e-23 1 1.35704615590908e-06 6.56977727153359 -3.89211404728533 4.5676885999191e-26 54.2848312874543 12.9376100930094 4.19589328300951 3.17384365492233e-05 -222.863305497105 26.3552834402796 -8.45611491912458 2.55430351240823e-16 HPS6 other 5.99189390537388e-22 3.86976982129847e-12 0.274696168333527 4.19589328300951 -8.45611491912458 1.43434327461407e-20 20.756931140192 2.68770743892867 7.72291315622722 5.65124400043281e-14 -24.168550118722 5.92732016241211 -4.07748349279089 5.24615366553604e-05 SENP8 other 1.71662203105812e-16 0.604461825343063 7.07987848374223e-10 7.72291315622722 -4.07748349279089 1.51688970324674e-15 882.958022408233 108.37853358183 8.14698255482085 2.57254233198579e-15 112.232679331135 220.778563494842 0.508349531560194 0.611414316319086 NOLC1 essential 1.5934926332607e-11 1 3.30648865930134e-11 8.14698255482085 0.508349531560194 1.88613315862438e-07 -4.2689604328154 12.8207752250264 -0.332972098635838 0.739287015032156 -182.352236253103 33.7585481806197 -5.40166109269439 9.98739765740125e-08 ALKBH3 other 0.00133764563609641 0.00132198481884354 1 -0.332972098635838 -5.40166109269439 2.75752719294923e-22 111.828387303368 47.3352070899807 2.36247804072749 0.0185101887227446 -663.21450067576 83.0264025282077 -7.98799514950003 8.46102758184478e-15 COPS2 essential 3.41547318118692e-18 1.26822342424271e-10 1 2.36247804072749 -7.98799514950003 2.94189009215412e-06 213.222027170406 44.313298207793 4.81169391117243 1.94654911169134e-06 55.4659381685347 81.1520553591815 0.683481618833199 0.494596805541861 GABRB3 other 0.0188104452492334 1 0.0184046218510417 4.81169391117243 0.683481618833199 1.93947378430059e-14 439.668386479029 79.7269303149142 5.51467847491906 5.40736524095584e-08 -921.497111455358 228.025269367129 -4.04120610848491 6.08420515378887e-05 SGPL1 other 1.95945036427888e-10 0.697249910624205 0.000560635628182302 5.51467847491906 -4.04120610848491 6.45179907351769e-55 810.485653641482 46.4575088663953 17.4457407084034 4.46998149667297e-54 -911.007580942661 378.614849630853 -2.40615913990402 0.0164664767199907 FRS2 other 9.83576768757772e-51 1 6.87661953448169e-50 17.4457407084034 -2.40615913990402 3.18531188441274e-106 1636.05295780119 57.985984362553 28.2146276516044 2.40212086049011e-107 368.71741832841 464.140831573585 0.794408492522282 0.427315926070045 CCT2 essential 4.97864247533711e-102 1 3.75595617746234e-103 28.2146276516044 0.794408492522282 9.72849648225117e-15 196.90643544813 39.7823570360265 4.94959198294395 9.9286572300462e-07 -569.021405635689 115.181253836763 -4.94022583260046 1.03961351194719e-06 PCBD1 other 9.94155055521247e-11 0.0131906162395859 0.00955136825530444 4.94959198294395 -4.94022583260046 4.63686374612532e-19 31.9253984352732 4.17176787815727 7.65272646218636 9.03976387930244e-14 -72.2556049446191 20.9589223615454 -3.44748664545801 0.000609689265208761 C16orf71 other 5.36995190438773e-15 1 1.12653537463867e-09 7.65272646218636 -3.44748664545801 0.266409678604714 62.1965413308688 79.1486844166614 0.785819016314263 0.432315656797887 -97.3927287124159 142.346015608142 -0.684197083397994 0.494142080068411 CLMP other 1 1 1 0.785819016314263 -0.684197083397994 0.0917835700089212 -3.80206760107357 4.23394468716889 -0.897996521446268 0.36958248874108 -16.2660847536665 7.57804607164182 -2.14647477725646 0.0322742546703034 SCN3B other 1 1 1 -0.897996521446268 -2.14647477725646 4.15536472489741e-60 291.251997208267 17.9152603302133 16.2572015053046 5.10764335696592e-48 -446.574896876383 68.9063030926969 -6.48090053932547 2.18834483841065e-10 COX11 essential 6.38596450922235e-56 3.10941918089769e-06 7.81214051447937e-44 16.2572015053046 -6.48090053932547 2.69551715648831e-38 41.0792533712542 7.64351473230489 5.37439316989016 1.13841351696754e-07 -103.754685821651 13.6847406089589 -7.58177950071823 1.46644900135293e-13 ZNF202 other 3.91793418695576e-34 2.17313077510491e-09 0.00115810807081108 5.37439316989016 -7.58177950071823 1.09572238226954e-27 41.5258270365365 5.80250703635733 7.15653195702205 2.73029053265018e-12 -62.3769497614735 11.3675333092027 -5.48728981607433 6.29847902059772e-08 FAM227B other 1.46552868628551e-23 0.000839020390333822 3.28781585941735e-08 7.15653195702205 -5.48728981607433 2.87691989914724e-24 67.3339058400085 8.21134842006091 8.2001033685901 2.03965021979227e-15 -174.196319695025 31.6136248903163 -5.51016595848784 5.7482832669751e-08 STXBP4 other 3.67641593912026e-20 0.000766878470647148 2.62727344811442e-11 8.2001033685901 -5.51016595848784 0.990969403614487 -3.50734458360747 27.8825948311677 -0.125789748222676 0.899950698572385 -6.90356343280201 78.3359701407235 -0.088127630517633 0.929811762092324 CYYR1 other 1 1 1 -0.125789748222676 -0.088127630517633 1.93830649722677e-35 196.601600381398 31.5415715838621 6.23309462747213 9.23308913702688e-10 -379.070301028857 60.3198414471705 -6.28433848522058 6.79740626150808e-10 CUL5 other 2.77468575078012e-31 9.55919242555882e-06 1.02939710788713e-05 6.23309462747213 -6.28433848522058 4.10871883883093e-84 22.2392935434278 0.942091700927793 23.6062938687668 1.08147515149141e-84 -3.89130338700285 7.48378852264375 -0.519964370349176 0.603305922879105 MYRFL other 6.39809697582753e-80 1 1.68558717111451e-80 23.6062938687668 -0.519964370349176 3.25625038425968e-26 19.0893972319838 63.648033590474 0.299921241162129 0.76435158753365 -1408.9699774983 132.032559580957 -10.6713827405154 2.84848020279688e-24 WBP1L other 4.27708487972509e-22 4.43052610743027e-20 1 0.299921241162129 -10.6713827405154 1.44201192335967e-16 4.51410594291312 21.8334155150832 0.20675216572481 0.836280634639959 -373.535159669563 45.291607175158 -8.24733726548886 1.21984045319852e-15 BORCS7 other 1.56342932730656e-12 1.8409832119672e-11 1 0.20675216572481 -8.24733726548886 1.22056322423671e-10 369.723842537537 53.5731564890882 6.90128912999261 1.48477039456816e-11 458.228733239193 183.789744779454 2.49322253420104 0.0129646384993592 C2 other 1.04736530271752e-06 1 1.75277145078771e-07 6.90128912999261 2.49322253420104 0.0283720354000992 30.1022327497428 11.5975804169586 2.59556145915795 0.00971311793749867 -2.23208105324641 45.6645610122022 -0.0488799411134153 0.961033924686969 PLEKHF1 other 1 1 1 2.59556145915795 -0.0488799411134153 0.00742952004134405 0.492782669958079 9.47357844105277 0.0520165292370047 0.958536132374409 112.907830641394 36.5425139321971 3.08976637050448 0.00211379043037403 TMEM100 other 1 1 1 0.0520165292370047 3.08976637050448 2.05962999212786e-33 343.548662124641 45.0328000484424 7.6288541186664 1.07711886821416e-13 -928.256553600428 117.204766241251 -7.91995567560563 1.36216124048145e-14 ANAPC16 other 2.90469617789792e-29 2.0379294318843e-10 1.34025900771888e-09 7.6288541186664 -7.91995567560563 9.45641970624138e-10 25.2892564712085 27.6031184010061 0.916173893971585 0.359980160654853 -345.856182499855 62.0075427965318 -5.57764695876965 3.84011194264003e-08 SMPD1 other 7.74859030729419e-06 0.000515381423821718 1 0.916173893971585 -5.57764695876965 1.03009478185557e-06 27.059756143709 28.7444353743913 0.941391117663658 0.346922305714646 -281.341789570148 63.8929185905703 -4.40333288533903 1.28386590825407e-05 APBB1 other 0.00686558172106735 0.154051070331406 1 0.941391117663658 -4.40333288533903 0.346705864030771 -126.699942084812 109.717278267733 -1.15478568266739 0.248699572485836 -346.772869524394 288.418513777462 -1.20232527719062 0.229775429383184 SYNPO2L other 1 1 1 -1.15478568266739 -1.20232527719062 9.62574351293115e-19 10.1628558835277 2.00981345395014 5.05661650515543 5.86836104674193e-07 -30.4946057311832 5.15262594860457 -5.91826498475826 5.80929314562673e-09 NUDT13 other 1.10609418707092e-14 7.99242550975326e-05 0.00572517303720143 5.05661650515543 -5.91826498475826 2.70089471465229e-28 2.73957797658796 0.859204532851531 3.18850503208571 0.00151282571012447 -12.4162163368899 1.64021047168029 -7.56989212742328 1.62140386668356e-13 C11orf65 other 3.63540428592198e-24 2.40210982849169e-09 1 3.18850503208571 -7.56989212742328 7.12141171753674e-16 429.959981401117 81.0792639928983 5.3029586139161 1.68061586685603e-07 -1045.61133941487 222.770902093858 -4.69366209674155 3.42721086724428e-06 TRIM44 other 7.56365138519577e-12 0.0424391521690859 0.00169372467061751 5.3029586139161 -4.69366209674155 1.38789252375564e-18 246.755594832174 57.7972905209258 4.26932807071355 2.32200307552727e-05 -764.616411831672 128.076615481286 -5.96999232809516 4.33875237604293e-09 ILK og 1.58802662568121e-14 5.98921377988966e-05 0.203128829047126 4.26932807071355 -5.96999232809516 1.15562850597852e-25 437.091984192589 76.0386761953911 5.74828503154664 1.52023492038836e-08 -1112.6840065549 168.498838007937 -6.6035114527169 9.74414312765163e-11 TAF10 essential 1.50693957179599e-21 1.39360735011674e-06 0.000161616174386486 5.74828503154664 -6.6035114527169 1.78164019260505e-12 453.493875958258 118.424934342401 3.82937831864929 0.000143888677239624 -1123.22828547162 259.785859328338 -4.32366984244509 1.83485948641749e-05 TPP1 other 1.66753550663576e-08 0.218036352770991 1 3.82937831864929 -4.32366984244509 0.247589133158375 56.2322413412205 47.4738148806272 1.18448962828491 0.236761443296326 -66.2859927244857 111.3609752338 -0.595235382819878 0.551945583406582 DCHS1 other 1 1 1 1.18448962828491 -0.595235382819878 0.582468890818213 2.27575311837847 3.88180794776008 0.586261131154531 0.557946843278074 -4.05716519688859 7.79418001829223 -0.520537784265541 0.602903747836134 NETO1 other 1 1 1 0.586261131154531 -0.520537784265541 0.785664649243134 -5.00543886479946 15.6077207588625 -0.320702743349456 0.748560662620781 -28.4832699228314 41.5447020084461 -0.68560534907774 0.493258422716756 MSS51 other 1 1 1 -0.320702743349456 -0.68560534907774 6.58842409932463e-10 228.398434802184 161.320309708655 1.41580706864915 0.157411720414467 -1719.91680989809 326.311446991831 -5.27078294602748 1.97104990403927e-07 CYB5A other 5.44401483327195e-06 0.00257320564972327 1 1.41580706864915 -5.27078294602748 2.97534524952716e-09 238.644008306715 45.3177215065136 5.26601956968233 2.02709680486818e-07 -211.199200472922 119.059985401265 -1.77388901704567 0.0766534434203139 USP54 other 2.37462304364763e-05 1 0.00203500248240716 5.26601956968233 -1.77388901704567 0.0806083817935449 1.84223853556992 2.20671312893787 0.834833722340984 0.404191784791029 -9.99500635856293 5.91034066247558 -1.69110495136442 0.0914113840747749 RAG1 other 1 1 1 0.834833722340984 -1.69110495136442 1.0910598230344e-13 31.3867632584467 5.7107886119809 5.4960471120572 6.07763732905012e-08 -54.7897133765719 15.2943233012863 -3.58235616556921 0.000372312721408082 C11orf74 other 1.07152985220209e-09 1 0.000628731581690235 5.4960471120572 -3.58235616556921 5.84154577660712e-14 3.80511010459899 0.480926464800978 7.91204140985183 1.45956987446442e-14 0.693004107171126 2.1573167928617 0.321234280224486 0.748158074801239 WDR88 other 5.79831833786023e-10 1 1.85117247178322e-10 7.91204140985183 0.321234280224486 7.16929253450242e-21 71.7351005737267 17.2429453194977 4.16025796315732 3.72575133659803e-05 -227.45497291338 35.4947695780354 -6.40812648222211 3.33473767101056e-10 ATP9B other 8.64616679660991e-17 4.72032117331545e-06 0.320265584893967 4.16025796315732 -6.40812648222211 5.20976889987913e-08 170.740617251762 49.2545765664918 3.4664924389568 0.000569041693554772 -325.287590936198 109.558215096484 -2.96908443287186 0.00311880129827779 PPFIBP2 other 0.000385627093969054 1 1 3.4664924389568 -2.96908443287186 0.00856387832731542 11.2921219711012 9.05964690964969 1.24641965450924 0.213182559839272 -97.7522918521245 40.8996522504189 -2.3900519068869 0.0172080200292799 MOGAT2 other 1 1 1 1.24641965450924 -2.3900519068869 0.0300964276930816 77.0446678730969 34.2373470348032 2.2503106854272 0.0248279380861124 164.067818224509 74.6372218011897 2.19820371478369 0.0283550622365236 CYB5R2 other 1 1 1 2.2503106854272 2.19820371478369 0.689657543102899 -8.37595338500829 13.0252702317934 -0.64305409684042 0.520460449762581 7.33564837669097 28.4481041753064 0.257860711261683 0.796612104067071 SERPINB7 other 1 1 1 -0.64305409684042 0.257860711261683 5.65114788769055e-10 117.239166977377 19.580468899271 5.98755666069579 3.87159585174652e-09 -119.360361230329 85.7810305205997 -1.39145403716811 0.164656516139956 KIAA0355 other 4.69384343551577e-06 1 4.20765037167812e-05 5.98755666069579 -1.39145403716811 8.15423593744815e-05 55.1887331394749 13.4409756382656 4.10600648529979 4.64654342991768e-05 9.69025438692471 29.3297736357975 0.3303896752581 0.741233211605806 SERPINB8 other 0.448727603637772 1 0.395885500228986 4.10600648529979 0.3303896752581 1.26881451100478e-05 129.294330531165 27.2024975144135 4.75303160905198 2.56741465428113e-06 146.845577069842 57.6198955974594 2.54852209548808 0.0110911551577172 TUB other 0.0764333861429277 1 0.0241054561890455 4.75303160905198 2.54852209548808 0.196771279556182 10.2132124299074 11.1060694175747 0.919606392316042 0.358185319047501 -24.4713536445421 23.5246987891357 -1.0402408916642 0.298689251407031 RIC3 other 1 1 1 0.919606392316042 -1.0402408916642 1.48924879075835e-46 540.542099089378 35.2152359440709 15.3496656943566 2.03805289705146e-44 -49.3354755400552 85.070343455107 -0.579937420448882 0.562197814758571 IDH3A other 2.23208608758862e-42 1 3.1008974828638e-40 15.3496656943566 -0.579937420448882 3.60897273309325e-12 507.196300521517 70.7105101522525 7.17285590825794 2.4284969099824e-12 140.187748453358 144.382166749222 0.970949194140092 0.332007473301813 WDR72 other 3.33541259992478e-08 1 2.92755302498378e-08 7.17285590825794 0.970949194140092 0.00496910444702572 292.511934920633 153.165773115524 1.90977350207352 0.0566899674962514 1133.47807158975 370.006463827156 3.06340073053222 0.00229712428607008 CRABP1 other 1 1 1 1.90977350207352 3.06340073053222 0.0160885673472672 10.4341834548443 24.197432856431 0.431210348500716 0.666488476813796 -126.981115502312 51.0551673193787 -2.48713542956337 0.0131801517690837 PLD4 other 1 1 1 0.431210348500716 -2.48713542956337 1.5559232939845e-75 361.14811289864 17.3465938895259 20.8195404353535 1.23714515238298e-70 -99.6713410320693 79.4317123532913 -1.25480539294882 0.210107715775765 XRRA1 other 2.41417058294635e-71 1 1.92079156358981e-66 20.8195404353535 -1.25480539294882 6.89294290684166e-09 -2.49189151850692 17.4131287958382 -0.143104180054218 0.88626089312943 -209.888776831964 36.4534127707788 -5.75772639318456 1.4263450307519e-08 TRIM66 other 5.39165994173154e-05 0.000194111295235027 1 -0.143104180054218 -5.75772639318456 2.18684902226226e-86 369.585068568771 16.2989277451939 22.6754222330822 7.15592759113613e-80 -146.103817689295 73.4894126699554 -1.98809341891811 0.0473202457851327 RNF169 other 3.40689209178237e-82 1 1.11439260376763e-75 22.6754222330822 -1.98809341891811 7.82534170952447e-06 408.923434070409 364.584430458914 1.1216151867914 0.262520931962343 -2999.83076824278 768.340845933523 -3.9042968808954 0.000106372677090975 RPL27A essential 0.0480241220713517 1 1 1.1216151867914 -3.9042968808954 0.772479410202074 -45.0202572987707 62.6786266667582 -0.718271278311964 0.472898397731989 -41.7107550440261 132.48544021913 -0.31483274671569 0.753009365525621 ST5 other 1 1 1 -0.718271278311964 -0.31483274671569 0.000453634976817037 85.8368335283949 69.8525384655987 1.22882912223252 0.219664266244139 -337.513374914414 147.997090900665 -2.28054060292949 0.0229594494324521 CDYL2 other 1 1 1 1.22882912223252 -2.28054060292949 0.673007695966284 1.17379333266038 5.65179351739704 0.20768510545321 0.835553293366873 -13.447226119004 17.4981137890292 -0.768495752235596 0.442529288031077 TMEM130 other 1 1 1 0.20768510545321 -0.768495752235596 2.89866387704363e-07 4.38780938344173 8.63443480638029 0.508175634171148 0.611537314577549 -78.9505511130848 16.1870321495634 -4.87739508908151 1.41559085952487e-06 PRTG other 0.00202413698533957 0.0178449383751705 1 0.508175634171148 -4.87739508908151 5.94029726438637e-37 125.342803171521 14.9496671642329 8.38432065373359 4.32931535523867e-16 -125.202018522172 31.6803775250806 -3.95203682225858 8.76282111525337e-05 CENPN essential 8.57006686333021e-33 0.992038978457835 5.64282963401808e-12 8.38432065373359 -3.95203682225858 1.35816848252754e-20 65.9215217018225 9.69233408683982 6.80140832034775 2.73679749111705e-11 -79.8423473092774 20.4229054844414 -3.90945095300486 0.000104189579191737 AKIP1 other 1.62654257467499e-16 1 3.20478986209807e-07 6.80140832034775 -3.90945095300486 6.14087216134881e-38 313.030651892245 43.0602912816707 7.26958974440312 1.25016268966111e-12 -495.446171767265 91.2506124154412 -5.4295106482313 8.50322852947893e-08 ATMIN other 8.90979141890099e-34 0.00112820836129126 1.51669737509685e-08 7.26958974440312 -5.4295106482313 6.62370996495649e-06 12.0077108952185 3.46029784971992 3.47013795248593 0.000561230606461428 -5.46094238758044 7.35517839178329 -0.742462262190817 0.458126013278039 C16orf46 other 0.0408550430638516 1 1 3.47013795248593 -0.742462262190817 9.38192377679789e-27 185.3240293984 29.3777615964291 6.30831007291331 5.87833647742936e-10 -388.070522449935 61.5047877871643 -6.30959859243549 5.8329424809778e-10 TMEM41B other 1.24122851567036e-22 8.21628277870533e-06 6.60372319874414e-06 6.30831007291331 -6.30959859243549 1.62785806481927e-06 25.0932022306456 5.21726262509419 4.80964905043334 1.95659332750619e-06 13.8763280572656 11.1067855852052 1.24935589607038 0.212068293259012 PKD1L2 other 0.010664098182631 1 0.0184937201315885 4.80964905043334 1.24935589607038 1.67949657981419e-38 306.165100129823 34.3696117253259 8.90801742471299 7.93358839295026e-18 -546.784101232178 75.4535569166979 -7.2466312202596 1.48466295596259e-12 LEO1 other 2.44333162431368e-34 2.17725822491913e-08 1.06444955468214e-13 8.90801742471299 -7.2466312202596 2.65101225174525e-07 21.5946648481333 8.79011712149448 2.45669819294305 0.0143356025869681 -65.8422321906983 18.4015859125409 -3.57807378688083 0.000377273975930892 ZNF143 other 0.00185676898112237 1 1 2.45669819294305 -3.57807378688083 2.47933735462435e-23 295.04504592484 37.2801425990105 7.91426816947506 1.43201841088953e-14 -234.87162400836 75.3794359056467 -3.11585807437391 0.00193214033185793 TMX3 other 3.1224774644139e-19 1 1.81708816157772e-10 7.91426816947506 -3.11585807437391 0.0425344545821451 -186.924179122729 98.2920218345216 -1.90172280144387 0.0577493538656657 -616.80265162641 269.628877739417 -2.2875986311174 0.0225539774840211 MFAP4 other 1 1 1 -1.90172280144387 -2.2875986311174 7.34002729190141e-09 263.779024575294 62.8187027241947 4.19905240217097 3.1348013067654e-05 -327.818687438099 131.507207368939 -2.49278114862871 0.0129731762608538 WEE1 essential 5.72889130132905e-05 1 0.271536489192019 4.19905240217097 -2.49278114862871 9.7576346282186e-32 76.0604511822169 7.43482447213978 10.2302954786942 1.53757684715114e-22 -57.8244859313907 20.394772039459 -2.83526022352758 0.00475370486439888 MAPK7 other 1.3567990950538e-27 1 2.16152553172508e-18 10.2302954786942 -2.83526022352758 0.0656923859412842 -8.604111220411 7.17412364999974 -1.19932574906362 0.230927285181587 66.0594323510418 39.9698712756505 1.65273067544966 0.0989669372519277 PRKCB other 1 1 1 -1.19932574906362 1.65273067544966 1.41516351870966e-26 120.107452469078 18.7475380916143 6.4065719926608 3.2930015414149e-10 -345.569667641783 48.2377813577212 -7.16387980365662 2.64462837626841e-12 NDST2 other 1.86787432834489e-22 3.86962024015594e-08 3.73558094858106e-06 6.4065719926608 -7.16387980365662 1.37863043180813e-08 573.406312718126 126.105571447388 4.54703393463751 6.72959019100964e-06 -1061.58010641422 401.845992469361 -2.64175859983265 0.00848810937213215 MCM7 essential 0.000105630663685139 1 0.061427699263536 4.54703393463751 -2.64175859983265 0.0324381626470491 2555.49159587428 1566.67191936888 1.63115937949775 0.103431224801033 -2548.53344965265 3518.59459507534 -0.724304372325135 0.469187999648712 CLEC3A other 1 1 1 1.63115937949775 -0.724304372325135 0.0585384035530963 0.371571816526762 13.8968426976956 0.0267378587071707 0.978678731707848 -62.14383697912 28.9819192850889 -2.14422779829812 0.032462043819095 CCDC68 other 1 1 1 0.0267378587071707 -2.14422779829812 2.01728060182685e-06 10.0037177661527 3.10528959052361 3.22150880764259 0.00135099649757647 51.9015979885128 11.0003627411217 4.71817150124455 3.02565350436703e-06 CLEC4E other 0.0131123239118745 0.0375695395637254 1 3.22150880764259 4.71817150124455 2.50042715370627e-30 124.617736760898 21.17448213927 5.88527907984974 7.00208200697813e-09 -595.904757637055 67.2347115981888 -8.86305218647072 1.14458099522566e-17 ZNF3 other 3.43108614031575e-26 1.74766072161006e-13 7.54474336251893e-05 5.88527907984974 -8.86305218647072 6.93603362056109e-20 29.5567852462863 6.7388954477467 4.38599848824918 1.38946585421374e-05 -153.16821876774 21.4012587464056 -7.1569724277767 2.71661335499511e-12 ZSCAN21 other 8.19492372269293e-16 3.97467699969334e-08 0.12377361829336 4.38599848824918 -7.1569724277767 1.57473301394315e-18 97.9079306607668 14.411047105832 6.79394980404614 2.86088011924497e-11 -243.955401807183 51.5820394665665 -4.72946406016586 2.86963993797603e-06 RIMKLB other 1.80023478153981e-14 0.035683972628732 3.34837409156431e-07 6.79394980404614 -4.72946406016586 1.07343134807005e-15 707.126052748117 83.2522962175056 8.4937723627547 1.90487795074144e-16 972.108222883616 280.550588622227 3.46500154449007 0.000571900672064575 A2ML1 other 1.1338655329664e-11 1 2.49881889578263e-12 8.4937723627547 3.46500154449007 0.394689392739242 -1.75447449260138 3.01591065118431 -0.581739545868979 0.560986250558877 -8.77495248844757 6.54960961858311 -1.33976725323453 0.180887697209669 BEAN1 other 1 1 1 -0.581739545868979 -1.33976725323453 0.000400713491702397 46.3535272934746 27.6755285798912 1.67489221243473 0.094537577928161 -115.847305106165 60.1025458479835 -1.92749414307966 0.0544451881430183 TK2 other 1 1 1 1.67489221243473 -1.92749414307966 1.43060990415353e-14 992.563592893438 144.321343051984 6.87745535000958 1.68171106565616e-11 -935.677545357602 354.12805090732 -2.64220115565621 0.00847449966345543 TMED3 other 1.45221211370625e-10 1 1.98223283308891e-07 6.87745535000958 -2.64220115565621 1.70638328353641e-13 276.324035471466 45.3163667096231 6.09766527052108 2.04672753551745e-09 -198.739414133427 99.3751565583237 -1.99989032486994 0.0460106513947146 SEC11C other 1.66457689308977e-09 1 2.24833019776592e-05 6.09766527052108 -1.99989032486994 1.15378100874865e-22 138.139447200859 30.2010901223863 4.57398877461263 5.9762212591169e-06 -416.342570801979 68.8784932392545 -6.04459463646776 2.84325095573208e-09 TMEM135 other 1.43830340550606e-18 3.94188312502696e-05 0.0547302342909926 4.57398877461263 -6.04459463646776 3.42822276347722e-11 11.065199749078 3.70274559173249 2.98837699619018 0.00293174479508207 -42.8682693207449 8.19660288654225 -5.23000441940759 2.42515183612209e-07 IQCD other 3.02746352242673e-07 0.00315585008434568 1 2.98837699619018 -5.23000441940759 8.69656386014093e-29 192.024365695482 21.6363684662684 8.87507374423083 1.01369199555298e-17 -135.838199198293 38.6531034459314 -3.51428959354597 0.000477726836216062 NDEL1 other 1.17664509027707e-24 1 1.35753632044456e-13 8.87507374423083 -3.51428959354597 6.33453526314356e-10 145.38297634364 23.272619165958 6.24695378319508 8.51157085815784e-10 36.5414623632221 42.2165076538364 0.865572838541071 0.387110266045388 CENPV other 5.24372829083024e-06 1 9.50231770604742e-06 6.24695378319508 0.865572838541071 0.280019518166652 -8.69733987859734 15.5211771999322 -0.560353107664755 0.575474498317686 -52.3578340381778 34.0321034154048 -1.53848363114922 0.124524944104309 RRAD other 1 1 1 -0.560353107664755 -1.53848363114922 1.59446422320839e-45 255.23622412088 29.2865181240191 8.71514404819433 3.69702359813609e-17 -357.825873800414 64.2143183236192 -5.5723689535578 3.99747262738557e-08 FAM96B essential 2.38468069223047e-41 0.000536101054058679 4.90927763596492e-13 8.71514404819433 -5.5723689535578 7.65025894503713e-20 218.364547738147 26.1833000200447 8.33984056902593 6.38670915440639e-16 -699.033333132146 177.119195896736 -3.94668307742146 8.9857445913699e-05 BLCAP other 9.03113068461633e-16 1 8.30016721706654e-12 8.33984056902593 -3.94668307742146 0.0090906509736687 6.98101084133336 2.55217693652102 2.73531616928153 0.00643693730546357 12.4997689740465 4.92598022113259 2.53751911557057 0.011444236152015 CHRFAM7A other 1 1 1 2.73531616928153 2.53751911557057 0.00012847114978366 27.0901325317112 6.84352103468075 3.95850796606413 8.55062080769871e-05 -12.6794526371857 35.6225053696014 -0.355939384544405 0.722024969958731 ATF7IP2 other 0.689504660888904 1 0.710898613952071 3.95850796606413 -0.355939384544405 0.0300444259924455 -64.3434165689896 26.9754995558003 -2.38525393888968 0.0174093284887832 -125.20245252961 54.4307654831046 -2.30021480349148 0.0218143190961649 MMP10 other 1 1 1 -2.38525393888968 -2.30021480349148 2.66230469549664e-23 46.0861495374073 5.40963335480785 8.51927413831991 1.59325869015954e-16 -105.05709307366 28.143920626002 -3.73285209511989 0.000209330417550142 TVP23A other 3.35130915069117e-19 1 2.09258596365554e-12 8.51927413831991 -3.73285209511989 0.00760718575191999 16.3900836831673 5.22380167524556 3.13757770721585 0.00179539235205579 17.1682458936992 9.63066490287141 1.78266465159435 0.0751964235871723 TMPRSS5 other 1 1 1 3.13757770721585 1.78266465159435 2.02191294871467e-55 368.1897478219 23.5743999569383 15.6182023082007 1.81079051807901e-45 -442.644258688501 78.1445931305824 -5.66442591810321 2.4287194252453e-08 COG1 essential 3.08543915973859e-51 0.000327949983990872 2.76000690765603e-41 15.6182023082007 -5.66442591810321 1.88026214790049e-11 96.6399203306863 26.0407636257495 3.71110162972054 0.000227714044758049 -282.708777778372 65.1736094549618 -4.33777997171905 1.71744443765274e-05 PLEKHA7 other 1.68057830779346e-07 0.204427411413806 1 3.71110162972054 -4.33777997171905 2.94704033850019e-35 139.556820522496 10.79829255884 12.9239710595032 1.97859033878601e-33 -76.4928750964721 52.2396352386581 -1.46426893578051 0.143710016039798 ZNF606 other 4.21367827598756e-31 1 2.94354884701194e-29 12.9239710595032 -1.46426893578051 0.00991779877645215 7533.09824085227 2727.48621442269 2.76191982236902 0.00594567680668507 693.617903895982 4857.15305990044 0.142803386128046 0.886499734985492 B2M other 1 1 1 2.76191982236902 0.142803386128046 4.02011930417506e-20 238.141483074736 27.6970232324851 8.59808944361309 8.90454016538679e-17 -176.74663300718 72.6217547707345 -2.43379733201388 0.0152663966005351 ZNF592 other 4.77067557826454e-16 1 1.1751321656261e-12 8.59808944361309 -2.43379733201388 8.20278745100888e-29 166.078136144049 107.589434548898 1.54362867358104 0.123278558615327 -1837.55630362125 187.192730265574 -9.81638710549429 5.3087072205149e-21 CASC4 other 1.11008322574503e-24 8.20195265569553e-17 1 1.54362867358104 -9.81638710549429 0.060684791120269 -249.010004512641 138.778471511839 -1.79429850898306 0.0733186338625322 -588.462010706996 256.404337075289 -2.29505482403055 0.0221083503734998 NNMT other 1 1 1 -1.79429850898306 -2.29505482403055 0.263626310012241 -125.826282962227 85.2454943887268 -1.47604614020359 0.140507966145458 -481.471987150475 452.604450854916 -1.06378093772837 0.287898183337235 ACSM1 other 1 1 1 -1.47604614020359 -1.06378093772837 2.42527856730127e-44 732.576690154745 78.769889040338 9.3002122902521 3.46256944579379e-19 -821.989908613003 172.378360703649 -4.76852143887224 2.39043551588903e-06 AP1G1 other 3.61318000956544e-40 0.0298493682869064 4.7184433837832e-15 9.3002122902521 -4.76852143887224 4.68732233476104e-15 615.069737596961 73.4350614085306 8.37569582975131 4.75627893009028e-16 700.071022591551 211.594299804469 3.30855331754435 0.00100028488394709 SLFN5 other 4.84669129414291e-11 1 6.19410205065657e-12 8.37569582975131 3.30855331754435 6.24754129110842e-15 6.67215272853176 4.73660403550384 1.40863637292029 0.159566743146791 -57.9640580940198 8.83533291791384 -6.56048375681423 1.34666878189413e-10 CATSPER2 other 6.43559228397079e-11 1.91994568234646e-06 1 1.40863637292029 -6.56048375681423 0.271397149209828 19.4081680970015 12.7685611986026 1.51999648160246 0.129093905118441 43.6697000494615 51.4013946850429 0.849582006812137 0.395931934933398 ZNF667-AS1 other 1 1 1 1.51999648160246 0.849582006812137 1.5622195835866e-09 219.39554121763 44.2043163858635 4.96321534083926 9.28474203522008e-07 -592.372009864627 225.399071061599 -2.6281031553264 0.00882828814720438 C16orf45 other 1.2663351944553e-05 1 0.0089523482703592 4.96321534083926 -2.6281031553264 7.04703953906811e-11 52.0186912826107 9.90065467018062 5.25406581842347 2.13789883727967e-07 -59.54801343424 24.9860028843719 -2.38325488513754 0.017501889331167 SAAL1 other 6.12810558317363e-07 1 0.00214381037710529 5.25406581842347 -2.38325488513754 0.787802009649268 0.851683626806929 1.40269594120721 0.607176225286528 0.543996972863283 -0.16041715305252 3.61801244063029 -0.044338474697056 0.96465149429651 YPEL4 other 1 1 1 0.607176225286528 -0.044338474697056 7.75469788290381e-09 1871.1496571325 300.888372989807 6.21875029114497 1.00933406286305e-09 1198.88126455465 673.450224097016 1.78020768522595 0.0756083643157308 PPIB other 6.04323606014694e-05 1 1.12419627921686e-05 6.21875029114497 1.78020768522595 0.0257606377719302 6.19918608418001 2.32316831563736 2.66841883235622 0.00784703468050113 8.21109646212706 5.80605487603963 1.41422990954022 0.157863325316736 LDHC other 1 1 1 2.66841883235622 1.41422990954022 2.11547327320383e-30 217.630257431507 19.435550857986 11.1975348175986 2.65928839433475e-26 -97.1634341459418 43.2060928228075 -2.2488363977835 0.0249274530102761 FAM96A other 2.90433325678154e-26 1 3.83788501070392e-22 11.1975348175986 -2.2488363977835 2.54722253942859e-13 52.9614840813594 39.8255536350312 1.32983673162985 0.184136639703385 -630.717860203563 99.0141645118003 -6.36997608689003 4.06687358913672e-10 FAM111A other 2.4682586407063e-09 5.74730575616802e-06 1 1.32983673162985 -6.36997608689003 2.15320954619106e-07 103.968108044709 19.5090498403785 5.32922458527544 1.45211743460841e-07 -12.0094803939296 44.2604474912512 -0.271336623885321 0.786236027045533 PCLAF other 0.00152016593961089 1 0.00146809072638911 5.32922458527544 -0.271336623885321 0.00111206237970774 14.3947849377142 3.92345215616444 3.66890798326608 0.000267650359992128 25.7480918178415 24.4879829928291 1.0514582530289 0.293516732463391 KIF7 other 1 1 1 3.66890798326608 1.0514582530289 0.00014082855418022 15.1584259045675 20.9904549794252 0.72215804371205 0.470505919175555 -134.679500765198 45.9318690184374 -2.93215807767667 0.00350705169430879 LDHD other 0.75019370811803 1 1 0.72215804371205 -2.93215807767667 0.671866611998139 -14.6668077050636 137.288105792301 -0.106832326226808 0.914961605176743 -767.22214516516 860.061647253669 -0.892054828412635 0.372760134526726 PLIN1 other 1 1 1 -0.106832326226808 -0.892054828412635 1.64428902690302e-29 128.67277978231 13.4941795919154 9.53542813817305 4.94128789317054e-20 -534.153622025345 84.5126977189916 -6.32039488079565 5.43753689831339e-10 PEX11A other 2.23837065232308e-25 7.6636645044829e-06 6.79822388342403e-16 9.53542813817305 -6.32039488079565 1.33142956103917e-34 131.713285599407 14.8687136604773 8.85841832770747 1.13476723527942e-17 -90.7175930812 32.4906505530427 -2.79211377848833 0.0054196465087018 TMEM170A other 1.89422483649043e-30 1 1.5184320375274e-13 8.85841832770747 -2.79211377848833 0.419724254191976 1.04960210888006 6.67354757857628 0.157277983939088 0.875084019868389 -53.1363625310627 41.6411391729156 -1.27605448809681 0.202479801972269 MESP1 other 1 1 1 0.157277983939088 -1.27605448809681 0.452220194056907 -147.410056504474 295.304871990771 -0.499179222851024 0.617854564423253 -2240.50546976023 1844.19226569147 -1.21489798620328 0.224931081269449 ANPEP other 1 1 1 -0.499179222851024 -1.21489798620328 0.217054086989082 21.6776205431442 18.2630782665392 1.18696422513071 0.235761708167238 -95.3934118945884 100.800851539618 -0.946355218607416 0.344389145791852 SCNN1G other 1 1 1 1.18696422513071 -0.946355218607416 0.000217876011458383 24.7538494501062 6.03466358265146 4.10194356505125 4.73008227675068e-05 22.4154162436073 13.7117616824306 1.63475830186934 0.102683577985366 RBPMS2 other 1 1 0.402624603397017 4.10194356505125 1.63475830186934 0.00612004457718538 162.379466896756 86.1922847643679 1.88392113448052 0.0601106612138629 -417.990678703857 231.833265095573 -1.80297973429974 0.0719466919432912 NAV2 other 1 1 1 1.88392113448052 -1.80297973429974 0.0152597021718887 11.7727612894365 4.18447736917978 2.81343648221095 0.00508041233641709 0.628105314441813 9.50783016582138 0.0660618988231108 0.947353040297915 ANKDD1A other 1 1 1 2.81343648221095 0.0660618988231108 8.71093999126686e-10 64.3211706387333 10.2554720903602 6.27188783431952 7.32387615069451e-10 18.7357823699646 21.3701409714794 0.876727130390456 0.381025442280529 C18orf54 other 7.1516817328301e-06 1 8.19541741262715e-06 6.27188783431952 0.876727130390456 2.57860129639432e-24 412.305629145924 40.8973215080965 10.0814824526907 5.12638746164417e-22 -367.174705493174 224.16252783387 -1.63798431897276 0.102007485452309 DCTN5 essential 3.29957821886617e-20 1 7.17386661382484e-18 10.0814824526907 -1.63798431897276 0.00072754466195715 67.8973863332331 30.274013427421 2.24276132056327 0.0253170786903509 591.867372705372 165.935057048265 3.56686153748221 0.000393390830543635 PLK1 essential 1 1 1 2.24276132056327 3.56686153748221 3.43603247733533e-44 373.111842585571 26.4673768128436 14.0970465348313 1.2408693917902e-38 -160.894324886235 60.1227128552788 -2.67609888584906 0.00767553249812983 CLPX other 5.11659596200003e-40 1 1.87110695588044e-34 14.0970465348313 -2.67609888584906 3.77719788440546e-06 41.1917923769919 8.33448924857699 4.94232953555311 1.03486414517202e-06 57.03012967208 24.9175667882798 2.2887519538587 0.0224833894020985 ZBTB39 other 0.0238907766188645 1 0.00994711416339347 4.94232953555311 2.2887519538587 1.01865769947682e-08 198.622471189118 32.5992196616534 6.09285968347145 2.12698570558372e-09 245.172376728579 97.6407079350195 2.51096475961381 0.0123349781807254 NEMP1 other 7.8711680438574e-05 1 2.33500490758981e-05 6.09285968347145 2.51096475961381 0.000412542767661255 100.760905216261 28.2576998528134 3.56578581204759 0.000395405308490998 -67.0573105505903 84.146089232009 -0.79691535474333 0.425855027964401 NAB2 other 1 1 1 3.56578581204759 -0.79691535474333 1.11513133769154e-42 95.4611437718363 51.6573192385017 1.84796937160236 0.0651777229813825 -1047.76265668417 86.5981874821123 -12.0991291751989 7.59327222141472e-30 VPS39 other 1.65150951112117e-38 1.18796743904033e-25 1 1.84796937160236 -12.0991291751989 9.4341223054985e-10 105.11747024455 83.6663127427285 1.25638942124512 0.209526224394474 -1485.46691234315 250.732107886359 -5.92451810366632 5.62917614609484e-09 STAT6 other 7.73315005381712e-06 7.74743512987034e-05 1 1.25638942124512 -5.92451810366632 3.68872522467855e-16 234.744222622564 42.6616610599768 5.50246326069076 5.81993682215795e-08 -391.120165547119 105.433764294147 -3.70962915120761 0.000229299702829641 PATL1 other 3.95246907824307e-12 1 0.000602363461093348 5.50246326069076 -3.70962915120761 4.48923484101129e-07 25.6942352293758 4.70847587052728 5.45701750118525 7.44503688959101e-08 24.1277980686629 13.5877657778259 1.77570017493512 0.0763560733024734 ATP23 other 0.00308746168865972 1 0.000766392097414498 5.45701750118525 1.77570017493512 0.114972268130395 10.0632992096756 9.31843963236293 1.07993393815911 0.280650151995175 -20.5448874830603 19.1426902797253 -1.07324974613522 0.283634920103964 ELFN2 other 1 1 1 1.07993393815911 -1.07324974613522 9.65295806603932e-19 133.639912055143 35.5919576673141 3.75477834920757 0.000192582362095615 -553.265451138986 88.6681520236806 -6.23973138620533 8.94260354824956e-10 STX3 other 1.10912488178792e-14 1.254200147642e-05 1 3.75477834920757 -6.23973138620533 4.10932550478451e-21 89.7176154523944 17.7043458629561 5.06754760367149 5.56231121694832e-07 -259.586220761711 44.5183431511634 -5.83099465045854 9.54767107759966e-09 MRPL16 essential 4.97598225374357e-17 0.000130621688012641 0.00543604675232359 5.06754760367149 -5.83099465045854 9.67827840390318e-15 289.254693995649 51.7763123908281 5.58662215671599 3.75522307573507e-08 -666.735209856512 147.242344129418 -4.52814856893671 7.39968717598983e-06 PIP4K2C other 9.89120052878905e-11 0.0900689923061483 0.000392157945799013 5.58662215671599 -4.52814856893671 2.62024451917762e-30 136.560292416423 31.8899298876909 4.28223871602596 2.18673956431677e-05 -480.634759879906 59.3496274618026 -8.09836186738059 3.66586566806485e-15 MTMR10 other 3.59392738250402e-26 5.51199561850231e-11 0.191755192394938 4.28223871602596 -8.09836186738059 1.05798911078236e-52 1876.93668889436 112.58789280815 16.6708572483247 1.35797352457354e-50 -2006.03585703241 744.362853017601 -2.69497040173359 0.007260025080322 YWHAB other 1.60793185056702e-48 1 2.08204500787615e-46 16.6708572483247 -2.69497040173359 0.344078640881417 22.0453001826044 21.5598854042414 1.02251471977989 0.306991001411142 -15.821819614859 39.2584384513662 -0.40301703885801 0.68709373725667 SCG5 other 1 1 1 1.02251471977989 -0.40301703885801 0.602601092889531 17.8459631596031 110.09617998761 0.162094299380882 0.871291672196354 189.249012510444 200.474354326755 0.944006095672397 0.34558482786434 GREM1 other 1 1 1 0.162094299380882 0.944006095672397 0.083803782278955 2.70931110183559 1.55082610007698 1.74701154546026 0.0812027797878089 -4.03992799084907 4.94493399828219 -0.81698319780456 0.414297648938394 NYAP1 other 1 1 1 1.74701154546026 -0.81698319780456 1.41227512022148e-12 179.844310799141 37.5522585249421 4.78917428307778 2.16514702190852e-06 -504.54872311207 119.738402573345 -4.21375859597769 2.94264729401475e-05 TSC22D4 other 1.32694904309347e-08 0.344495718710307 0.0204173364165974 4.78917428307778 -4.21375859597769 0.654674647394928 -0.807651894576276 0.981085238669694 -0.823222960393752 0.410745963832432 0.145790410061554 2.57509065230954 0.0566156418341227 0.954872393856272 MS4A6E other 1 1 1 -0.823222960393752 0.0566156418341227 0.000330644827497642 -200.355109580635 109.512719659062 -1.8295145094048 0.0678758242325498 -1156.77509593416 287.442079024074 -4.02437631908887 6.53190243163105e-05 MS4A7 other 1 0.746596447935429 1 -1.8295145094048 -4.02437631908887 0.000924803894470162 -35.5655309309372 18.483373111772 -1.92419049898882 0.0548598258279291 -181.938815881038 48.815567128931 -3.7270654953266 0.000214305192625168 MS4A14 other 1 1 1 -1.92419049898882 -3.7270654953266 1.1616284095249e-51 389.068073929303 26.7959345197227 14.5196680355722 1.48447930532814e-40 -298.879686970223 61.6603931012538 -4.84719074819109 1.64007780157617e-06 DIS3L other 1.76195797156737e-47 0.0206141378880109 2.24586874103095e-36 14.5196680355722 -4.84719074819109 3.9622930136839e-32 59.9442386674558 34.9733374920045 1.71399823311573 0.0871192948745188 -616.509110628799 60.2107286716434 -10.2391903275395 1.48137595558392e-22 CCNDBP1 other 5.53017235919862e-28 2.29776224470622e-18 1 1.71399823311573 -10.2391903275395 3.35615368621851e-05 -1.71362919209335 3.13325277906242 -0.546916994231831 0.584668586065297 -22.7664447992982 5.39606764377324 -4.21908069028183 2.89078104032673e-05 EPB42 other 0.193650067694808 0.338626091063873 1 -0.546916994231831 -4.21908069028183 1.12165545388645e-13 280.264074186276 61.1602074838306 4.58245787116356 5.71560003700789e-06 -698.12147567763 141.512884259966 -4.93327147791819 1.07901544664772e-06 SMAD3 ts 1.10112915908032e-09 0.0136819158634931 0.0524291991394733 4.58245787116356 -4.93327147791819 0.304597615489776 13.8897297307394 15.9724974891725 0.869602874575815 0.384910373344795 -33.54593782436 40.6888234069109 -0.824450918348804 0.410053571831385 MS4A8 other 1 1 1 0.869602874575815 -0.824450918348804 0.157621392095206 -3.97463115552093 2.83759899280392 -1.40070220126258 0.161877502634887 4.20485029383655 6.14409468043546 0.684372639507979 0.494033490377389 CCDC178 other 1 1 1 -1.40070220126258 0.684372639507979 0.184198769999509 -10.3055587274258 13.1756803633933 -0.782165204618827 0.43446612831925 -60.4230926322818 32.8093815695815 -1.84164070584926 0.0660852406315924 MS4A15 other 1 1 1 -0.782165204618827 -1.84164070584926 0.000185697084216047 -17.4128191200428 41.7075909322301 -0.417497600097223 0.676486470725684 -276.249897688121 72.5216365139666 -3.80920661704758 0.000156032410085273 MAP1A other 0.973609812544736 1 1 -0.417497600097223 -3.80920661704758 9.68491935876689e-28 132.814059945062 11.3037554884862 11.7495517379462 1.62225981269961e-28 124.829645229705 28.5890698265109 4.36634161192435 1.51731433669948e-05 RCCD1 other 1.29622960697736e-23 0.181182504945284 2.36914823046652e-24 11.7495517379462 4.36634161192435 4.36440903541814e-36 173.337710891091 22.1764916829083 7.81628191553331 2.94030423363452e-14 -194.136109842363 49.5969583844005 -3.91427450727349 0.000102478819236675 AKTIP other 6.2729651066065e-32 1 3.70684154734304e-10 7.81628191553331 -3.91427450727349 3.78470731409644e-05 211.910263974745 48.5111126364835 4.36828290380986 1.50087455506454e-05 49.2358691418663 105.375123370689 0.467243762730073 0.640513269926865 MAPRE2 other 0.217280046902277 1 0.133277660489731 4.36828290380986 0.467243762730073 0.0224778822176299 -17.2321279083553 15.7331851059548 -1.09527268587421 0.273885449139771 -131.780235536183 48.4334350432636 -2.72085255605904 0.00672138120876648 EVA1C other 1 1 1 -1.09527268587421 -2.72085255605904 1.28278812716108e-12 110.151843724597 49.9352720852348 2.20589253096646 0.0278315023358101 -932.07359011549 143.12401779408 -6.51234925123827 1.75809446215561e-10 MBD6 other 1.20748846409673e-08 2.50194422909365e-06 1 2.20589253096646 -6.51234925123827 3.94176471021592e-08 32.2348169884364 9.28813087200442 3.47053862963927 0.00056127403118333 -107.47944569574 29.5926309309257 -3.63196655095032 0.000308288825140063 CNPY4 other 0.000293819141499495 1 1 3.47053862963927 -3.63196655095032 1.3003685220227e-07 1583.37404558772 436.928195141775 3.62387701959574 0.000319548767610839 -1649.98697387118 769.699602808174 -2.14367653023512 0.0325347992009488 PDIA3 other 0.000933664598812296 1 1 3.62387701959574 -2.14367653023512 1.56811036527117e-43 617.237606136696 71.4774916560221 8.63541223728285 6.44584145442102e-17 -693.496544046148 153.221013706941 -4.52611901767317 7.37876791089956e-06 NUDT21 essential 2.33005519175644e-39 0.0898291205472913 8.52849282834445e-13 8.63541223728285 -4.52611901767317 0.00230002228415736 -233.839501675149 167.593897745125 -1.39527455844944 0.163502380911713 -1140.80451225406 339.989099103056 -3.35541496849069 0.000847749600761816 NKX3-1 other 1 1 1 -1.39527455844944 -3.35541496849069 5.83275305385649e-06 15.3442493864859 7.68273424427833 1.99723807938736 0.0462978667568187 -50.8153287969893 16.9111427531801 -3.00484299249579 0.00277985842004241 SGSM1 other 0.0361572361808564 1 1 1.99723807938736 -3.00484299249579 1.15009125927931e-32 24.9971309148171 3.79061898391649 6.59447204292474 1.01507658190648e-10 -56.1199537485911 8.2164999761761 -6.83015321746631 2.28419073788751e-11 DUSP18 other 1.61231293638366e-28 3.30019877809987e-07 1.1690636993817e-06 6.59447204292474 -6.83015321746631 6.98500712365427e-07 4.8320377605392 29.588906099637 0.163305724931767 0.87033826380123 -258.458985073937 55.6853097584067 -4.64142134066009 4.33974907248982e-06 TEF other 0.0047316438255634 0.0534917470675095 1 0.163305724931767 -4.64142134066009 0.894460412246287 -1.50495944413013 3.8397062029743 -0.391946509596064 0.695251233960948 0.275478128294518 7.21221448528089 0.0381960532173204 0.96954538018572 MEI1 other 1 1 1 -0.391946509596064 0.0381960532173204 9.42456692626091e-15 110.485457537999 13.3243585812618 8.29199070740831 9.50880523041767e-16 108.580275277607 65.3663730396405 1.66110295291679 0.0972932211603937 B4GALNT2 other 9.63473476871652e-11 1 1.23139027733909e-11 8.29199070740831 1.66110295291679 0.156193513675815 27.7440717207122 51.1252179771077 0.542669015770947 0.587580368500619 -184.660819605242 116.881914766784 -1.57989214989931 0.114713878401572 PBX3 other 1 1 1 0.542669015770947 -1.57989214989931 0.201501919617498 0.761444687047641 0.448366625075231 1.6982635291373 0.0900539674803056 1.98698834311387 2.19958806230332 0.903345666021292 0.366759139613258 GNGT2 other 1 1 1 1.6982635291373 0.903345666021292 7.78025324061403e-59 786.933740387359 43.6883712167088 18.0124302754137 1.11232773576119e-56 -325.421669701728 217.007085986826 -1.49959006279401 0.134329823949333 PHB essential 1.193646452175e-54 1 1.71498690299661e-52 18.0124302754137 -1.49959006279401 4.37261884634592e-22 358.710596765493 37.5491968507617 9.55308307102224 5.41311579091784e-20 -16.5306535200567 85.89038320877 -0.192462216402928 0.847457379323868 SNRPD1 essential 5.39756070392941e-18 1 7.44249290093294e-16 9.55308307102224 -0.192462216402928 2.69303834692382e-07 5.55145485571455 2.03980446143609 2.72156226769214 0.00670716381687849 -17.1094915902217 4.65877991893554 -3.67252625965017 0.000264070120564846 TTC16 other 0.00188566545051606 1 1 2.72156226769214 -3.67252625965017 7.6505260586731e-22 78.8502108216376 9.4173895668487 8.37283094873847 5.16333761378312e-16 -188.949227032602 45.1829323297279 -4.18187172212998 3.38889345633525e-05 SAMD14 other 9.40173147350338e-18 0.39483997659762 6.72060023810011e-12 8.37283094873847 -4.18187172212998 0.000124930554118 3.12149363951347 4.056739343874 0.769458763533124 0.441956210887384 -33.8770832276236 9.16493109258604 -3.69638166238134 0.000240934359089455 PIP5KL1 other 0.671876520046602 1 1 0.769458763533124 -3.69638166238134 0.00311748294163406 2.08809629121832 1.18167462786724 1.76706535113397 0.0777971125449245 18.8102130977572 5.81462181279453 3.23498478548805 0.00129295784822172 TMEM92 other 1 1 1 1.76706535113397 3.23498478548805 1.14622830737941e-20 812.404918199242 181.563082496628 4.47450498762231 9.33839081003715e-06 -2831.64164109816 410.184879773432 -6.90333013411472 1.42524964351122e-11 FAM102A other 1.37478623187086e-16 2.06532925841211e-07 0.0843727726120753 4.47450498762231 -6.90333013411472 5.30231905827752e-17 162.839407592733 34.929686003421 4.66192016661086 3.97610279806236e-06 -1111.54905780167 168.660983679793 -6.5904338605778 1.06727176090985e-10 ACSF2 other 5.82300678980038e-13 1.524917891988e-06 0.0368266641156536 4.66192016661086 -6.5904338605778 1.20047047957778e-27 502.632374351626 68.0059098072824 7.39101021920012 5.55407093320029e-13 -939.25383099352 152.458415295269 -6.16072146082884 1.41294274788864e-09 GOLGA2 other 1.60466889005162e-23 1.97289195887691e-05 6.78985171583735e-09 7.39101021920012 -6.16072146082884 3.65109375868661e-27 211.791855217012 29.4607700333776 7.18894499285192 2.1719870865691e-12 -411.643422948526 66.0626313799982 -6.23110848522996 9.29691544461966e-10 TRUB2 other 4.85449426154972e-23 1.30342754533568e-05 2.62050241994562e-08 7.18894499285192 -6.23110848522996 7.88786752759241e-19 96.3500747295682 41.7354794730572 2.30858914156642 0.0213410866560105 -737.683130738651 93.5873567721526 -7.8822947477255 1.77023475085054e-14 COQ4 essential 9.08051309776438e-15 2.64632392904647e-10 1 2.30858914156642 -7.8822947477255 2.28248028809258e-11 175.149272681535 49.4550480551367 3.54158532989927 0.00043192503461427 -516.550431633815 110.897665127052 -4.65790177856334 4.02206913170395e-06 SLC27A4 other 2.03232044851764e-07 0.0496323330852268 1 3.54158532989927 -4.65790177856334 2.16252551169645e-21 179.210237210886 31.1187740929422 5.75891057519297 1.41824099862027e-08 -416.632385881893 69.7805284644755 -5.97061092900716 4.27294213899307e-09 URM1 essential 2.63179354773458e-17 5.90007850552163e-05 0.000150971754303128 5.75891057519297 -5.97061092900716 0.0125407348556641 56.6836853932585 79.9128787108368 0.709318526721673 0.478431281015611 -448.365529754472 180.891070568075 -2.47864932385226 0.0134907633085195 CERCAM other 1 1 1 0.709318526721673 -2.47864932385226 2.53388464144403e-26 115.36638016243 14.8467889747406 7.77046002059484 3.92467975746927e-14 -172.251902177479 32.8657658074329 -5.24107374179982 2.28773866581239e-07 DOLPP1 other 3.3343387996762e-22 0.0029790932906209 4.9352847950176e-10 7.77046002059484 -5.24107374179982 1.09226362662871e-44 54.0482747350509 8.2836083422959 6.5247260012381 1.5724452729317e-10 -207.464297526469 19.4879019996041 -10.6457995083659 3.76649278578014e-24 CCDC103 other 1.62900197275405e-40 5.85614298333096e-20 1.79997810392492e-06 6.5247260012381 -10.6457995083659 1.05475971404289e-06 52.119386563934 20.8453599419963 2.50028719623743 0.0127024574454822 -163.601733895684 46.0531584702697 -3.5524541492914 0.000414796153488746 ENDOG other 0.00702449202414333 1 1 2.50028719623743 -3.5524541492914 0.084908576716889 9.50936570862245 14.6227048217337 0.650315097278631 0.515764259339621 71.3878656313365 32.1237526046231 2.22227665957877 0.0266766004539854 PRRX2 other 1 1 1 0.650315097278631 2.22227665957877 0.177545441157172 154.132211725213 82.8482689872229 1.86041559599735 0.0633631874837085 107.52285949942 162.822674075206 0.660367851775706 0.509295781343643 UGT1A6 other 1 1 1 1.86041559599735 0.660367851775706 7.80104830829379e-06 161.674110571022 33.1203440364353 4.88141398510735 1.39031362793467e-06 118.166726802845 63.8852366188584 1.84967189693344 0.0649090727624718 C15orf39 other 0.0478828345163073 1 0.013258030755985 4.88141398510735 1.84967189693344 0.0356596101781313 -12.4853290278907 7.62319814200105 -1.63780722937018 0.102043370990422 -35.8290168223339 15.005103018707 -2.38778879276375 0.0172922588603313 ISLR2 other 1 1 1 -1.63780722937018 -2.38778879276375 4.23347656805533e-35 101.797292183739 9.15386058972948 11.1206950538393 5.705569518705e-26 -132.115073101707 29.5258494759212 -4.47455620910921 9.37374134868529e-06 SP2 other 6.04540453918302e-31 0.113347280388303 8.21773177779081e-22 11.1206950538393 -4.47455620910921 6.74605052388631e-38 395.556269437338 34.6263695536822 11.4235559354294 3.59498780999427e-27 -565.568713297675 111.790185761418 -5.05919826007543 5.81337597629649e-07 PRR15L other 9.7851462848971e-34 0.00746088672797891 5.21273232449169e-23 11.4235559354294 -5.05919826007543 6.5656671874508e-39 162.591231907078 13.3643655582206 12.1660269766465 2.63221797415424e-30 -292.974598828302 70.8885375469397 -4.13289099996322 4.14414797518305e-05 COQ7 other 9.56814679227205e-35 0.480389633283219 3.87409841436021e-26 12.1660269766465 -4.13289099996322 0.000403434276622165 128.870542211318 47.1582986891494 2.7327224644126 0.00648485426079176 871.930776884187 247.654427397626 3.52075586149018 0.00046627936838753 GPRC5B other 1 1 1 2.7327224644126 3.52075586149018 1.58416275966169e-31 342.988795717519 39.8838282126356 8.59969594415355 8.72407731762782e-17 -368.328348139482 73.2169890743379 -5.03064046741276 6.66947467444013e-07 CRK other 2.19850107785849e-27 0.00853596439318351 1.15175268747323e-12 8.59969594415355 -5.03064046741276 6.19967192622105e-34 234.20327863374 18.7291476980005 12.504748342539 1.08862096269362e-31 -40.7881207923558 40.0037063870506 -1.01960854321136 0.308370729429205 FBXO22 other 8.77501564437328e-30 1 1.61007040382387e-27 12.504748342539 -1.01960854321136 0.000197296256887737 148.300805204834 39.8053259969141 3.72565232140871 0.000215242308367675 -72.662620147195 92.4724650821238 -0.785775745057343 0.432342251688668 TBC1D2B other 1 1 1 3.72565232140871 -0.785775745057343 5.69482650357015e-05 31.7033580255082 12.0785349640576 2.62476849384869 0.00892937116003796 -47.3578961415227 31.2163903485799 -1.51708431412785 0.129861361213508 NOD2 other 0.319650611645393 1 1 2.62476849384869 -1.51708431412785 0.902494429212492 -0.10053399962029 8.49064174081386 -0.0118405654942466 0.990557419545286 8.08188853223091 21.9436535705613 0.368301864876014 0.712800089580354 SNX20 other 1 1 1 -0.0118405654942466 0.368301864876014 4.18000355724622e-13 24.8354615841963 6.02416939507076 4.12263665834459 4.34096963679418e-05 -50.521596120776 12.4819775639669 -4.0475634459256 5.93931518755779e-05 KATNAL2 other 4.00569247664336e-09 0.681001879405376 0.370892445767695 4.12263665834459 -4.0475634459256 2.99791018776949e-35 147.306086694105 24.3067097212941 6.0603055034247 2.54829947352619e-09 -410.185082108755 50.1302638798056 -8.18238425978032 2.00118157083917e-15 HDHD2 other 4.28551261341648e-31 3.01538039094046e-11 2.78885894382706e-05 6.0603055034247 -8.18238425978032 0.00199671777869598 70.5042518953946 38.8075432146749 1.81676669160375 0.0698143509220043 -351.93615804943 148.910816531712 -2.3634022446884 0.0184659173254457 ZNF91 other 1 1 1 1.81676669160375 -2.3634022446884 0.213495323451491 817.63337905322 1421.02111356074 0.575384398761274 0.565268393596727 4909.20527354706 2827.44141689489 1.73627126072815 0.0830799540046731 IGF2 other 1 1 1 0.575384398761274 1.73627126072815 3.06447772347266e-40 73.4649681992597 11.1892773723212 6.56565797367657 1.20562879805376e-10 -144.264220142135 20.5205217472349 -7.0302413320253 6.17097790546103e-12 RNF214 other 4.49283079038326e-36 8.98741222151345e-08 1.38562917760319e-06 6.56565797367657 -7.0302413320253 1.9121800838744e-32 201.395428303347 16.2922530596229 12.3614227919443 7.51360320152166e-31 -665.36843552502 292.929939027974 -2.27142516648487 0.0235412221314884 CDK12 other 2.67571359136544e-28 1 1.10825647222444e-26 12.3614227919443 -2.27142516648487 0.456713940796355 0.513310990297541 2.49074049263662 0.206087704365446 0.836801097080974 6.23914135520262 5.57876995089204 1.11837222364851 0.263911846442519 DPEP2 other 1 1 1 0.206087704365446 1.11837222364851 3.04252257848751e-52 71.3986335865408 7.6183751529525 9.37189783294805 1.99940240783584e-19 -104.857474122619 17.0762592575001 -6.14054123572551 1.60651290086814e-09 DUS2 other 4.62007053543328e-48 2.24028224026062e-05 2.73358297199315e-15 9.37189783294805 -6.14054123572551 3.82642487380195e-13 80.2093743648715 13.3495291542164 6.00840474883247 3.43249372092634e-09 -85.7232688028405 29.8628791928949 -2.87056275616036 0.0042569145152254 POP5 essential 3.67375052133725e-09 1 3.73901541020506e-05 6.00840474883247 -2.87056275616036 8.07917149061429e-11 77.7988951723027 15.0709357443198 5.16218080231847 3.43850917956888e-07 -156.938920072209 42.6270434545411 -3.68167499675586 0.000255039828042093 ENGASE other 7.00464168236259e-07 1 0.00340859414970663 5.16218080231847 -3.68167499675586 1.10266932215451e-36 373.361292336025 69.5699266087336 5.36670527821362 1.18710622006658e-07 -955.356476164484 128.070462504127 -7.45961603858263 3.43682066463177e-13 ATP5L other 1.58839515856357e-32 5.0744657113288e-09 0.00120645605145367 5.36670527821362 -7.45961603858263 0.573504503210605 -7.21971257199078 10.5359685381873 -0.68524431767456 0.49348003999802 -20.3685922425792 19.3980195306724 -1.05003462906985 0.2941658758279 CD3D other 1 1 1 -0.68524431767456 -1.05003462906985 6.52511713738012e-08 258.8089612808 79.9364887362257 3.23768238225746 0.00127930970543462 -957.285035410143 226.201678498116 -4.23199793107687 2.72325472966764e-05 TBC1D16 other 0.00047842158851271 0.319573942526498 1 3.23768238225746 -4.23199793107687 5.61535993473233e-16 69.3909477917607 9.46000137703735 7.3351942590829 8.31201250515326e-13 -86.8414601758858 26.6215869515642 -3.26206924981169 0.0011769455706582 TEPSIN other 5.9831660104573e-12 1 1.01182128225231e-08 7.3351942590829 -3.26206924981169 3.9450564012401e-11 331.872265695808 106.955991909434 3.10288614757389 0.00201652668991285 -975.054280721898 222.26842529522 -4.38683218017501 1.38294676103111e-05 MYO5B other 3.4752001838524e-07 0.165607874633475 1 3.10288614757389 -4.38683218017501 2.46771185492665e-13 303.332815493929 45.0469774922552 6.73369962604218 4.24112557439877e-11 -62.4165535086615 91.9228721123372 -0.679010044773007 0.497422410341584 ACAA2 other 2.39145955860941e-09 1 4.9349737183704e-07 6.73369962604218 -0.679010044773007 2.64254563435145e-13 539.518458313049 87.2321378286406 6.18485883462908 1.21925613724067e-09 -376.090860790447 188.434621067196 -1.99586922329062 0.0464444273049788 RRM1 essential 2.5579841740522e-09 1 1.35276468426852e-05 6.18485883462908 -1.99586922329062 0.000710388577093447 12.3277116402118 11.3358413376315 1.08749860491498 0.277296339088462 -72.733206673655 24.7394333720995 -2.9399705959184 0.00342144072711594 TRIM68 other 1 1 1 1.08749860491498 -2.9399705959184 6.48855667285548e-21 117.438962862505 16.352056414278 7.18190788284959 2.39813067579319e-12 -260.587963650474 46.6828021457012 -5.5820977249214 3.83478693467583e-08 FN3K other 7.83233675980386e-17 0.00051470510237219 2.89142615580385e-08 7.18190788284959 -5.5820977249214 1.43024224528353e-06 40.8808700101172 9.82299052646279 4.16175398927501 3.68069092149725e-05 -129.050674110474 60.7041568199311 -2.12589517540423 0.0339701876517395 PRRT2 other 0.0094143879990116 1 0.316613033067193 4.16175398927501 -2.12589517540423 5.22057205030518e-43 55.9332724349443 6.67481614113785 8.37974728475584 4.66530370945783e-16 -81.9783395500436 14.5722480444632 -5.62564810178288 2.97777536706056e-08 ZNF23 other 7.74210835060259e-39 0.000401076564189387 6.07655808156882e-12 8.37974728475584 -5.62564810178288 5.89331531851207e-13 79.1236533095257 17.8313787915115 4.43732670561582 1.10187011188979e-05 -255.981796332199 56.0290873392603 -4.56873043071735 6.06926345138205e-06 IRGQ other 5.61220417781905e-09 0.0742331612738538 0.0989369173465841 4.43732670561582 -4.56873043071735 9.94482837774781e-20 9.98323083796527 7.53685688839387 1.32458808569639 0.185861947961306 -225.79402828489 25.5562789211038 -8.83516841328705 1.36749784107366e-17 ZNF226 other 1.17169967946625e-15 2.08693845526251e-13 1 1.32458808569639 -8.83516841328705 1.26748997525206e-16 33.3562354226979 6.60875429653754 5.04728030820785 6.11084869126417e-07 -120.815392556737 22.1099572287135 -5.46429788655756 7.0691934264708e-08 ZNF180 other 1.37662086212126e-12 0.000940273417654881 0.00595441096476781 5.04728030820785 -5.46429788655756 2.41460211117499e-10 42.4596507381827 7.77817290995749 5.45882062917713 7.43900868535519e-08 -120.846782605638 46.2572320956556 -2.61249489281455 0.00924890841948661 ZNF668 other 2.04734113006528e-06 1 0.000765845944157316 5.45882062917713 -2.61249489281455 3.45799916985033e-28 173.005412832901 16.6755927775588 10.3747683899863 4.82199182865538e-23 -324.721921982308 99.0134828077474 -3.27957276902191 0.0011094134007313 ZNF646 other 4.64997148369774e-24 1 6.81058125879286e-19 10.3747683899863 -3.27957276902191 2.94164231738624e-12 233.868594877715 33.9443773440294 6.8897594587591 1.63043449597484e-11 -232.096763768951 200.555064165804 -1.15727201770917 0.247695635580375 VKORC1 other 2.73072656322964e-08 1 1.92293444455273e-07 6.8897594587591 -1.15727201770917 0.00586080360862542 5.34151496530989 5.1473130175714 1.03772880084726 0.299878631757493 68.4165803773413 21.384826811929 3.1993048612943 0.00146161270731104 LPO other 1 1 1 1.03772880084726 3.1993048612943 0.440682952250686 -1.20341953081015 2.78541880311414 -0.43204258169892 0.665896346402839 -24.5681149492664 19.6026943854617 -1.25330296265228 0.210680047256935 CA4 other 1 1 1 -0.43204258169892 -1.25330296265228 8.62703170551465e-57 187.481860176864 10.4547260933334 17.9327376445007 4.98103715611198e-56 -12.6260211390579 40.810066968669 -0.309384964958553 0.757156064217363 SMG8 other 1.31993585094374e-52 1 7.67428394642172e-52 17.9327376445007 -0.309384964958553 8.74562864933001e-12 2244.55843071793 341.798043126795 6.56691422275135 1.1962428505435e-10 -1660.35877983132 1252.53962600401 -1.32559381384873 0.185527619934006 TPM4 other 7.95240013083577e-08 1 1.3749615324147e-06 6.56691422275135 -1.32559381384873 1.46978216429313e-21 323.457838449166 41.0641689531898 7.87688748353547 1.82437094236894e-14 -599.710556222585 143.251248031469 -4.18642465223648 3.30296111034917e-05 RAB8A other 1.79460402260192e-17 0.385224354300023 2.30910630175637e-10 7.87688748353547 -4.18642465223648 4.85800243870668e-10 671.874610178917 316.367763726541 2.1237138773711 0.0341583781417032 -2550.60497335927 566.67523471763 -4.50099954452786 8.32716011346735e-06 GPX4 other 4.04865923241814e-06 0.10105841513704 1 2.1237138773711 -4.50099954452786 8.09084572951696e-27 275.14471825414 106.967926587025 2.57221699095282 0.0103771860048938 -1664.82292682899 191.986934296396 -8.67154284707096 5.26458810733811e-17 MIDN other 1.07122797458805e-22 8.01165018174714e-13 1 2.57221699095282 -8.67154284707096 0.270465401904293 -1.96211854749387 1.44420595193038 -1.35861408469563 0.174836155749014 -6.11185861309704 4.98818977740866 -1.2252658551159 0.221009219962902 FAM129C other 1 1 1 -1.35861408469563 -1.2252658551159 3.77146851523907e-19 34.9594233968014 6.92180172841164 5.05062478939622 6.03646885718135e-07 -147.424725873384 23.0502632310685 -6.39579359226908 3.46728616591919e-10 KLHL26 other 4.37829779934104e-15 4.90586319615906e-06 0.00588374619509466 5.05062478939622 -6.39579359226908 9.78697570571674e-17 369.30950359516 43.4757151678737 8.49461595212726 2.03116788419473e-16 4.23813878973193 140.838007220834 0.0300922944975111 0.976004816948206 GATAD2A other 1.06678035192312e-12 1 2.66204862902562e-12 8.49461595212726 0.0300922944975111 1.01067555880361e-25 157.311845933504 44.0700888131314 3.56958313836278 0.000389850774842211 -580.232660276087 94.7430735219828 -6.12427524996282 1.76967371913131e-09 MVD essential 1.31872946912695e-21 2.46568639286566e-05 1 3.56958313836278 -6.12427524996282 2.29828927197707e-21 157.735890035435 28.8951476441206 5.45890583353809 7.35896647011237e-08 -203.476034873055 62.1061949691013 -3.27625987994091 0.00112048976069256 CDT1 essential 2.79540924150572e-17 1 0.000757899956756873 5.45890583353809 -3.27625987994091 3.68654979844026e-30 105.924973300924 23.8941429127431 4.43309365344226 1.12844587323195e-05 -320.99785405396 51.3382755055482 -6.25260297298591 8.28201279285888e-10 TRAPPC2L other 5.04946725892363e-26 1.16229767534981e-05 0.101255448205103 4.43309365344226 -6.25260297298591 4.16660864464173e-33 491.482136763803 63.4437775494435 7.74673507391292 4.8442333370954e-14 -463.497944107008 136.734109343345 -3.38977557489438 0.000751705584891665 ANKRD11 essential 5.86283502387538e-29 1 6.0780595680536e-10 7.74673507391292 -3.38977557489438 2.15087018507479e-25 54.3034809404246 7.25295184118727 7.48708693087577 2.98068987058128e-13 -29.3065333580256 15.6408798255992 -1.87371386295418 0.0615230185495485 SPATA33 other 2.79419545743066e-21 1 3.67220992055613e-09 7.48708693087577 -1.87371386295418 1.51102529251155e-13 19.7082921757856 3.00609917443838 6.55610178911268 1.35102622186876e-10 -23.5885153150038 11.4112013688501 -2.06713689054642 0.0392232578302721 PROCA1 other 1.47672501837154e-09 1 1.5503025895944e-06 6.55610178911268 -2.06713689054642 1.04969531170136e-06 977.713284367138 709.211000487916 1.37859294863517 0.168604089286946 -4803.76362669262 1529.73787910575 -3.14025277945054 0.0017825305990955 RPL13 essential 0.00699202047124279 1 1 1.37859294863517 -3.14025277945054 0.0235470337841345 37.3129912970707 14.240466638038 2.62020846967214 0.009033105845978 -4.64528937396274 42.1909902186577 -0.110101454122982 0.912369519435294 ZNF641 other 1 1 1 2.62020846967214 -0.110101454122982 0.181608493673624 -37.2097998121987 52.879351065098 -0.703673533481736 0.481937174529547 229.299336489781 156.365160812069 1.46643494816195 0.14310763648932 LALBA other 1 1 1 -0.703673533481736 1.46643494816195 2.74540100484481e-07 184.104098766844 44.0369542008523 4.18067284869763 3.38682010423815e-05 -322.810371772743 131.052253895694 -2.46321877096193 0.0140781121559733 CACNB3 other 0.00192068254298943 1 0.292214838593667 4.18067284869763 -2.46321877096193 5.36692626205657e-37 164.098794782788 13.4013526347661 12.2449426751953 2.01283431091963e-30 -130.510976717586 50.919497953455 -2.56308451502967 0.0106587538874336 DHRS13 other 7.74662136665246e-33 1 2.96329467253587e-26 12.2449426751953 -2.56308451502967 1.52756696680431e-39 247.703672255138 18.4819164768535 13.4024884575882 3.48305875764865e-35 -89.5610120456285 70.0388853529429 -1.27873268676834 0.201587976680451 TP53I13 other 2.2325391219845e-35 1 5.2075211485605e-31 13.4024884575882 -1.27873268676834 1.17230373378546e-10 301.767737709717 74.3168225185255 4.06055758956182 5.63047173700032e-05 -999.890325977485 230.095102415586 -4.34555240628953 1.66406097957199e-05 KMT2D other 1.00700890732171e-06 0.198372709374777 0.476394213667597 4.06055758956182 -4.34555240628953 0.0646429117121866 -41.0591729126026 46.6970855699219 -0.879266284212162 0.379680974753504 -413.995769304689 176.628903503338 -2.34387329079958 0.0194768922706862 CORO6 other 1 1 1 -0.879266284212162 -2.34387329079958 0.129367760016703 5.72274292149479 3.29788839248137 1.73527489121271 0.083263690678368 14.9065086500461 10.2055407322337 1.46062898979615 0.144699934150635 RHEBL1 other 1 1 1 1.73527489121271 1.46062898979615 0.00518992668285963 664.005312304808 262.234398084828 2.5321060743908 0.0116218641776715 2144.12929197481 815.098504766412 2.63051555049689 0.00877028537882265 TUBA1A other 1 1 1 2.5321060743908 2.63051555049689 1.68182307797343e-11 1170.25827313816 216.089732513832 5.41561257688746 9.22815030615628e-08 4018.42883589974 671.667863383896 5.98276180083218 4.00981726180303e-09 TUBA1C essential 1.50624074863301e-07 5.54036451063324e-05 0.000944870309847342 5.41561257688746 5.98276180083218 0.015087771594809 13.0053652905344 4.49178271201412 2.89536830349097 0.00393986176843962 3.49241697991831 18.949079070631 0.184305367395462 0.853842839639079 ZNF610 other 1 1 1 2.89536830349097 0.184305367395462 0.000390351414602295 49.378675635152 16.0105969186975 3.0841245886021 0.0021455633849577 -135.966175910139 67.1007082960702 -2.02630015930997 0.0432232529115337 ZNF528 other 1 1 1 3.0841245886021 -2.02630015930997 2.94040806657376e-21 62.844547711279 6.43379984053014 9.76787423745851 7.13268527292237e-21 -37.7324076587026 27.8270336461515 -1.35596226814931 0.175673750758407 ZNF701 other 3.5699494336272e-17 1 9.88946813090686e-17 9.76787423745851 -1.35596226814931 1.37775556750353e-13 64.8663665931846 26.8883993703306 2.41242945330393 0.0161758440041537 -674.916132796389 104.230987565818 -6.47519656637817 2.11571881849849e-10 SERTAD3 other 1.34827159835895e-09 3.00664801296821e-06 1 2.41242945330393 -6.47519656637817 0.00376170736722831 33.8458940360282 14.5015788072196 2.33394546110925 0.01996447949087 -71.4246964071803 42.4278587699026 -1.68343862919256 0.0928681716022416 NCKAP5L other 1 1 1 2.33394546110925 -1.68343862919256 3.06223273101439e-07 50.0103177898011 58.8258306372615 0.850142144157392 0.395618696621787 -1117.9465050684 223.563073400869 -5.00058658195232 7.71449495075879e-07 RAB4B other 0.00213498866006324 0.00984986715312883 1 0.850142144157392 -5.00058658195232 0.105309227065354 676.765149708533 319.616368663912 2.11742956888474 0.0346781829074511 360.912568129355 933.889871137895 0.386461593902504 0.699306509599933 GPD1 other 1 1 1 2.11742956888474 0.386461593902504 5.43582982901684e-22 78.1251824615942 8.42476521516134 9.27327711412051 4.19431930014369e-19 -103.269724920242 38.6928616333769 -2.66896064443992 0.00783538773632223 PROSER3 other 6.69748593233165e-18 1 5.70972686328561e-15 9.27327711412051 -2.66896064443992 0.00154202238268379 27.2660327692833 8.53201196863369 3.19573306618903 0.00147552047445702 -15.354976713961 27.9707900638343 -0.548964712077069 0.583254498290013 CYP2S1 other 1 1 1 3.19573306618903 -0.548964712077069 0.0333752593463344 -20.9610040483207 44.1187480852312 -0.475104234776268 0.634902671291852 -373.251076447592 144.405997121919 -2.58473390223859 0.010003717943443 AXL other 1 1 1 -0.475104234776268 -2.58473390223859 1.52970671935517e-08 14.1337530088079 2.7394354416873 5.1593670702101 3.4775009336929e-07 -27.3344485766013 12.6418797263352 -2.16221394035722 0.0310369000414193 NFKBID other 0.000116961375761897 1 0.0034458556751963 5.1593670702101 -2.16221394035722 2.22305892087998e-11 389.916411916295 85.8518991428388 4.54173309861858 6.91345160525168e-06 -1671.04669310093 356.790171770405 -4.68355584126417 3.58713667553335e-06 TMC4 other 1.98096780439615e-07 0.0443585321296454 0.0630299382850796 4.54173309861858 -4.68355584126417 0.860161439933013 7.23086870057328 20.0811053101852 0.360083202038971 0.718927019058396 -27.1848664957921 80.2454191167487 -0.338771568458518 0.734914739393985 LAIR1 other 1 1 1 0.360083202038971 -0.338771568458518 0.0371014584490961 32.9415614426958 63.2837751908366 0.520537236335194 0.602905745034358 643.91770952516 250.118096539772 2.57445470133253 0.0103090940651114 TTYH1 other 1 1 1 0.520537236335194 2.57445470133253 3.25212830576291e-05 216.439171961849 87.9052493806596 2.46218711040332 0.014125213154728 -1161.05068284109 347.430183876391 -3.34182444912205 0.000890791986478843 LENG8 essential 0.187973016073096 1 1 2.46218711040332 -3.34182444912205 0.79169146109856 -6.66370901762583 10.039782502932 -0.663730416040365 0.507150392577651 -11.2574862279279 39.4957850935548 -0.285030065898475 0.775732033243433 CDC42EP5 other 1 1 1 -0.663730416040365 -0.285030065898475 0.2363518206957 1.39474554290094 0.82716692436145 1.6861718013902 0.0923468302108998 0.312230543626421 3.36369619892359 0.0928236455261142 0.926078479371543 LAIR2 other 1 1 1 1.6861718013902 0.0928236455261142 0.571077779461962 -0.530595386898599 13.4352528898543 -0.0394927725773797 0.968512303568414 -43.5037615383322 42.9372617401438 -1.01319366385348 0.311427376987932 TMEM145 other 1 1 1 -0.0394927725773797 -1.01319366385348 3.30645252623937e-23 52.2681052912884 6.3948985006711 8.17340654989336 2.16748472711151e-15 -77.6115713522179 20.2315272842389 -3.83616967032835 0.000139811639818766 ZNF526 other 4.15621082548289e-19 1 2.79085333462878e-11 8.17340654989336 -3.83616967032835 1.69462682628447e-41 246.102610791448 17.1148234775557 14.3795003853932 6.28320115714517e-40 -364.672361969775 141.843560706442 -2.57094759997247 0.0104087238504544 TRAPPC9 other 2.49787994194331e-37 1 9.49580190879349e-36 14.3795003853932 -2.57094759997247 0.315676899060633 5.03638563883231 7.50269767914277 0.671276633314611 0.50232977183895 41.0587894638102 28.1659049876341 1.45774792188771 0.145488129577659 NLRP7 other 1 1 1 0.671276633314611 1.45774792188771 6.31155620887295e-35 909.823149652496 69.4195297190537 13.1061554772068 2.8085679913584e-34 -67.110594367722 318.450592673173 -0.210740993773555 0.833168736106016 ZNF146 other 8.99775453136927e-31 1 4.18869830231192e-30 13.1061554772068 -0.210740993773555 7.5966526411486e-11 20.6571854695846 4.87943748684684 4.23351780308053 2.6984419848707e-05 -59.7528927772732 15.3724997537799 -3.8869991045263 0.000113948620638083 ZNF283 other 6.5946541577811e-07 1 0.234764452683751 4.23351780308053 -3.8869991045263 2.15779348044195e-18 85.85662910607 9.20390141081539 9.32828648133725 2.69815718316283e-19 51.9282939108416 54.982747309015 0.944447057528671 0.345360512898013 PPP1R14A other 2.46053190574795e-14 1 3.68217510786232e-15 9.32828648133725 0.944447057528671 1.49820721087643e-46 3512.4343862972 226.206170024832 15.5275799325528 2.82467316609751e-45 -1401.93379104045 1351.32224163118 -1.03745335335278 0.299985538275933 SPINT2 other 2.2453631469405e-42 1 4.30480190513261e-41 15.5275799325528 -1.03745335335278 5.26973064600676e-28 570.532935654693 48.6993414208655 11.7154137819664 2.00497220716449e-28 77.5562671315163 290.922671152524 0.266587223416684 0.789888012249998 C19orf33 other 7.07039760774727e-24 1 2.92705892523944e-24 11.7154137819664 0.266587223416684 1.31108233352374e-54 320.188825617933 18.2254362518057 17.5682393109362 4.64959308446405e-55 109.668913303296 108.87606367144 1.00728212983755 0.314247034208615 YIF1B other 1.99782725982348e-50 1 7.1589784721493e-51 17.5682393109362 1.00728212983755 0.00034227195843151 25.705251493635 7.69017066524397 3.34261131678273 0.000887223497962292 -51.5399515243513 29.3826072276024 -1.7540972836452 0.0799789715249063 DNAAF3 other 1 1 1 3.34261131678273 -1.7540972836452 0.287413784752442 65.8990041317374 47.82037676352 1.37805280074683 0.168770690024302 -209.335815550103 346.711975320514 -0.603774401955932 0.546252943441293 PSCA other 1 1 1 1.37805280074683 -0.603774401955932 0.0883890806021794 62.0316689155225 41.1921798551814 1.50590886749878 0.132690835235662 529.586806288723 297.62369711825 1.77938387103064 0.0757541758975997 LY6D other 1 1 1 1.50590886749878 1.77938387103064 3.5109071099115e-25 3087.1533579692 1524.79329295444 2.02463728836814 0.0433926346753235 -34808.3951637608 3679.38591667756 -9.46038169195156 9.16722139718663e-20 EEF2 essential 4.54662470733539e-21 1.41101871745497e-15 1 2.02463728836814 -9.46038169195156 9.92164339250408e-19 203.016577228053 23.301192810948 8.71271178583897 3.53377842594458e-17 -25.2534111718591 60.7901873925291 -0.415419202589309 0.677997955423242 CHAF1A essential 1.13959996006302e-14 1 4.69427126102478e-13 8.71271178583897 -0.415419202589309 3.25031484572269e-26 254.886274849738 60.0529995559895 4.24435543160669 2.57525085414505e-05 -1283.0996033025 152.997858062838 -8.38638932301598 4.27778459882744e-16 UBXN6 other 4.26961358134133e-22 6.47314365494568e-12 0.224355854413116 4.24435543160669 -8.38638932301598 3.10598112105474e-13 5659.25989592888 728.578598348265 7.76753518255792 3.97419287333626e-14 6888.74518987612 2247.96604789268 3.06443471258557 0.00228833022739471 PLIN4 other 2.99820357615414e-09 1 4.99675269964568e-10 7.76753518255792 3.06443471258557 0.00320560978833867 -11.7251305612101 23.4208108410021 -0.500628720363656 0.616833813812177 -201.888134186956 60.7338054212066 -3.32414761082074 0.000946271966464223 SEMA6B other 1 1 1 -0.500628720363656 -3.32414761082074 3.42548160257824e-19 191.415909264454 21.6656223343799 8.83500627446588 1.36325298525899e-17 -240.414859762479 97.7993464984618 -2.45824607597209 0.0142706353245102 ZNF444 other 3.98109471851644e-15 1 1.82185128950011e-13 8.83500627446588 -2.45824607597209 3.12976316332233e-13 295.852151011416 47.7540051511929 6.19533691623824 1.16119634405757e-09 607.735242116029 87.5375375249866 6.94256726084576 1.11942589334155e-11 NXN other 3.02053442892238e-09 1.62451085641726e-07 1.28950854007594e-05 6.19533691623824 6.94256726084576 4.94598121458146e-12 110.72911425825 14.9733573472184 7.39507591320662 5.51775596075789e-13 90.2286479947515 27.3142322179878 3.30335655326718 0.00101947843277311 FAM57A other 4.54931352117202e-08 1 6.74600843762259e-09 7.39507591320662 3.30335655326718 3.87216807231719e-71 270.9203220933 27.7747956643663 9.75417876578214 8.53031192398651e-21 -646.38797963924 50.9369898942206 -12.6899524487328 1.95260316901745e-32 GLOD4 other 5.99682669359764e-67 3.05797182299823e-28 1.18196002018757e-16 9.75417876578214 -12.6899524487328 2.24331058601294e-12 145.482039520423 20.9770840151193 6.93528420897616 1.27239086200578e-11 -283.150573623519 143.318051078439 -1.97567976603693 0.0487460054813346 MFSD3 other 2.08986814192966e-08 1 1.50549286792524e-07 6.93528420897616 -1.97567976603693 0.0432599589021846 16.1481284603771 6.81177627140107 2.37061932409234 0.0181404217683267 -23.9178906543793 46.5389040200213 -0.513933259882736 0.607527993050581 GPT other 1 1 1 2.37061932409234 -0.513933259882736 7.34487826191743e-14 239.019369505834 31.1524755057368 7.67256423849265 9.03246646856792e-14 -275.51922871441 212.837593277171 -1.29450453029513 0.19609474907559 KIFC2 other 7.26335011321015e-10 1 1.12580662064231e-09 7.67256423849265 -1.29450453029513 0.000903147528779189 125.929866657247 46.4071463993297 2.71358780765425 0.00686808733376696 -107.956815713647 85.1856358267663 -1.2673124367257 0.205588831224569 SLC43A2 other 1 1 1 2.71358780765425 -1.2673124367257 0.0545737354387597 11.812415491332 6.02857851900098 1.95940310872645 0.0505787007613289 -5.26147376379317 11.0213955674781 -0.477387253871798 0.633279188688882 RILP other 1 1 1 1.95940310872645 -0.477387253871798 0.044922914046045 66.8237647907769 30.8354204749954 2.16711054240251 0.0306604475691069 -13.5571328093441 56.3418202895316 -0.240622911004227 0.809938212009276 SERPINF2 other 1 1 1 2.16711054240251 -0.240622911004227 2.13453569351742e-17 46.2833375106252 23.7768933045653 1.94656791018777 0.0521028447392441 -316.875799807785 43.5199399458517 -7.28116353565854 1.17129553717943e-12 WDR81 other 2.36912116623498e-13 1.71969610768683e-08 1 1.94656791018777 -7.28116353565854 6.28922012269767e-62 196.083558832822 18.0722152866349 10.8500012711686 5.91943548117197e-25 -319.549076295445 32.9658850094465 -9.69332618262416 1.3480861793145e-20 SRR other 9.68225437889306e-58 2.08050140053607e-16 8.47722355258638e-21 10.8500012711686 -9.69332618262416 2.0273949879493e-45 469.154582739468 41.006838781248 11.4408863663494 2.67480528941516e-27 -371.590809431376 74.9539766869855 -4.95758631971153 9.56069115716416e-07 TSR1 essential 3.03156372548059e-41 0.0121554627372185 3.88167743599928e-23 11.4408863663494 -4.95758631971153 6.71399872659342e-08 27.9135375974957 5.92524824647919 4.71094820610799 3.12922655845212e-06 55.9496458241726 11.0417429146932 5.06710274423438 5.53036728264884e-07 TRPV3 other 0.000491800406722968 0.00710320373783417 0.0291862961106829 4.71094820610799 5.06710274423438 1.69801554048306e-06 45.2707862179062 9.86701517774618 4.58809329897544 5.56038552340526e-06 -16.225134140393 23.3758982173665 -0.694096714039376 0.487918394228841 HSD11B1L other 0.0111101156813807 1 0.0510276579482901 4.58809329897544 -0.694096714039376 6.96008378409987e-50 26.8056005448144 25.3371660273499 1.0579557522684 0.290541739919754 -699.653278226737 47.1858200983115 -14.8276172114633 4.57974358231362e-42 CYB5D2 other 1.0523646681559e-45 7.17966401399305e-38 1 1.0579557522684 -14.8276172114633 1.28118056864409e-15 85.0055683551616 29.0556854943572 2.925608771876 0.00358080987579081 -331.70103141819 54.3742943866354 -6.10032801638928 2.00599701037065e-09 GGT6 other 1.34972372906654e-11 2.7915454396318e-05 1 2.925608771876 -6.10032801638928 5.40391984128544e-07 261.955973136603 48.262969718239 5.42768036583558 8.59255237509608e-08 140.720775024536 173.367952917737 0.811688507917653 0.417323453152315 C19orf48 other 0.00368925607564557 1 0.000881424022637356 5.42768036583558 0.811688507917653 0.823100345288964 -5.14445164918782 8.33311827438986 -0.617350129902541 0.537260705000691 -1.4915673625125 29.9338326067904 -0.0498288135069663 0.960276994449631 KLK1 other 1 1 1 -0.617350129902541 -0.0498288135069663 0.391186843772917 -0.0641431975272214 9.6575031599803 -0.00664179927924065 0.994703075818237 -46.248095972518 34.4933928654118 -1.34078129550698 0.180549012805848 KLK4 other 1 1 1 -0.00664179927924065 -1.34078129550698 0.612894205831424 1.81251097278751 3.9816333654992 0.455217948616991 0.649133076390567 -11.0008877982603 14.450224347448 -0.761295294367049 0.446808784778428 KLK2 other 1 1 1 0.455217948616991 -0.761295294367049 0.00557342393738581 98.7847882217233 94.3661941759384 1.04682390854448 0.295643987775771 1098.3730243697 341.539715173549 3.21594524903663 0.00137710369962446 KLK5 other 1 1 1 1.04682390854448 3.21594524903663 0.00488947886878122 -32.5043674119646 117.454141110161 -0.276740922923089 0.782083777174267 1331.49716353822 425.101957867734 3.13218308900967 0.00182811144984459 KLK6 other 1 1 1 -0.276740922923089 3.13218308900967 0.469017838127778 -45.591013857137 91.3261967074342 -0.499210692011942 0.617832411707722 331.711758252887 332.542995090641 0.997500362810148 0.318964366710034 KLK11 other 1 1 1 -0.499210692011942 0.997500362810148 0.0175104693108286 5.31092240936855 47.8123805064362 0.11107839335993 0.911595076237085 489.842766112889 174.097606045707 2.81361000440343 0.00507572566928248 KLK13 other 1 1 1 0.11107839335993 2.81361000440343 2.6493096422899e-15 165.204955240602 23.7845147460085 6.94590396334768 1.07528759266334e-11 -391.348626430449 103.913555811011 -3.76609792029638 0.000183857768927362 ZNF83 other 2.76164037112299e-11 1 1.27486096986166e-07 6.94590396334768 -3.76609792029638 0.149994961155038 93.2078792454165 53.5636415275983 1.74013335514897 0.0823990314971776 215.224053181886 161.496168947556 1.33268828966325 0.183189988141664 KRT80 other 1 1 1 1.74013335514897 1.33268828966325 0.735720341686793 -14.2652265226192 23.3791823687236 -0.610167896277805 0.542003996217581 -45.0024070241749 71.1945432114312 -0.63210472311801 0.527582549742733 KRT1 other 1 1 1 -0.610167896277805 -0.63210472311801 8.85324750347563e-17 370.591022091176 65.7993299943057 5.63213975162433 2.89138731108114e-08 -595.636452433093 151.366905438066 -3.93505073456632 9.42577270379722e-05 OTUB1 other 9.65712237679122e-13 1 0.00030362458153663 5.63213975162433 -3.93505073456632 8.42535731001132e-05 75.8601238020838 18.7212000163056 4.05209728735401 5.83769895594913e-05 7.77007581016692 43.2531075735523 0.179642024493936 0.857502398658944 RCOR2 other 0.462383609173421 1 0.492876922850785 4.05209728735401 0.179642024493936 0.000111528801571043 210.80204783024 49.3541668895236 4.2712107429978 2.29887605578918e-05 123.390582188577 135.190307377128 0.912717668762786 0.361799862303638 ANGPTL4 other 0.602143999682061 1 0.201220621163227 4.2712107429978 0.912717668762786 1.6854640861047e-17 198.816560735081 30.0339690816413 6.61972316061984 8.64254790788301e-11 -330.413862486816 86.4303429945005 -3.82289195020133 0.000147142837765223 NDUFA7 other 1.87609007424314e-13 1 9.973500285697e-07 6.61972316061984 -3.82289195020133 2.1841734749414e-07 173.081373727641 35.5021922041208 4.87523059794462 1.42843259432082e-06 -111.066969232962 102.178326118098 -1.0869914731681 0.277521963215515 CD320 other 0.00154115280391866 1 0.0136115341912831 4.87523059794462 -1.0869914731681 5.35388470068778e-25 243.682728831736 42.7435944351606 5.70103502178292 1.9633794643713e-08 -961.335973008161 125.525283184531 -7.65850471410553 8.77273091156631e-14 SPRYD3 other 6.91668364481854e-21 1.30397872269522e-09 0.000207745181125128 5.70103502178292 -7.65850471410553 0.874674364329935 15.1719978383887 38.1927295480707 0.397248324953906 0.69134160553132 47.9516454177052 112.160740234053 0.427526114018518 0.669166914645589 IGFBP6 other 1 1 1 0.397248324953906 0.427526114018518 8.30248111120092e-27 81.9249331017965 9.35421761352176 8.75807432396826 2.77509929991878e-17 -189.816317196006 37.4807197896616 -5.06437224955225 5.6921172497153e-07 ZNF558 other 1.09908244950078e-22 0.00730583249000959 3.69171459868195e-13 8.75807432396826 -5.06437224955225 2.72352407069928e-21 626.882910418708 65.8892769052598 9.51418713123964 7.53626292647641e-20 -342.201154840326 273.571976408968 -1.25086333524441 0.211564702020231 NDUFV1 other 3.30799233627135e-17 1 1.03457817454668e-15 9.51418713123964 -1.25086333524441 5.95956753440379e-23 265.532795014891 28.3238022535879 9.37489933863857 2.34745812198427e-19 -304.631786046845 116.926309200888 -2.60533141026 0.00945037547015261 CDK2AP2 other 7.4637623800873e-19 1 3.20592355719391e-15 9.37489933863857 -2.60533141026 0.475004316254008 7.88725898376206 15.7104843404168 0.50203792657565 0.615859227065207 -62.3796885135603 65.2310149774565 -0.956288791997463 0.339383002096306 NUDT8 other 1 1 1 0.50203792657565 -0.956288791997463 0.863350793342986 4.59555441449857 11.9205487605292 0.385515340511436 0.700017657691419 -13.6250354947771 49.5358517803638 -0.275054026630831 0.783387004937786 TBX10 other 1 1 1 0.385515340511436 -0.275054026630831 1.18722755178821e-16 831.059826524622 140.994729602395 5.89426164274516 6.64010665260604e-09 -1946.63660311002 429.846191187685 -4.52868175412087 7.3121286808466e-06 PRDX2 other 1.29134740808004e-12 0.0890251666893074 7.16069101417035e-05 5.89426164274516 -4.52868175412087 1.77826659036943e-19 77.4935573525328 9.24423648667454 8.38290511760911 4.53893935861285e-16 -15.587584289133 17.3385191454572 -0.899014740438027 0.369046994904366 ZNF232 other 2.08306148395875e-15 1 5.91333019640082e-12 8.38290511760911 -0.899014740438027 2.01705216210054e-43 108.765691737481 11.7928381519768 9.22302929420335 6.26415830989978e-19 -158.428490152783 21.4468796856276 -7.38701818050262 5.65542931744634e-13 MIS12 essential 2.99612928158415e-39 8.32988184166671e-09 8.51236472732281e-15 9.22302929420335 -7.38701818050262 0.682810600729985 -1.38842203373041 1.63201420138752 -0.850741392170479 0.395290792263208 -2.04807517154388 5.34580507440996 -0.383118191373623 0.701783180943712 CD300C other 1 1 1 -0.850741392170479 -0.383118191373623 0.612078958906695 1.33169110646696 5.93151284282169 0.224511206795847 0.822444787513171 19.8514332121234 20.0263158509222 0.991267358404774 0.322000656471445 CD300A other 1 1 1 0.224511206795847 0.991267358404774 2.68320609288578e-36 1197.81103727272 119.445298631992 10.028113713903 8.26459913409193e-22 -2641.00167290872 377.460434013486 -6.99676425639452 7.83346713306805e-12 HID1 other 3.85898700278832e-32 1.13922112516209e-07 1.1544818530413e-17 10.028113713903 -6.99676425639452 7.9582122933343e-50 196.608873914626 12.5201802105331 15.703358147291 5.60100580967236e-46 -92.0969791112406 39.3862921002135 -2.33830031212157 0.0197391191856898 MRPL58 other 1.20288378813748e-45 1 8.54489446323615e-42 15.703358147291 -2.33830031212157 1.62737017973398e-39 752.369167791471 58.0273858362542 12.9657601656321 1.26326147051929e-33 -694.091964767373 189.582917676786 -3.66115245652411 0.000276013648873458 ATP5H other 2.37807604364527e-35 1 1.88023837272091e-29 12.9657601656321 -3.66115245652411 0.126005085679268 -2.76040382453157 3.09980542251831 -0.89050874112253 0.373585712648278 -11.386559683045 5.58385575392176 -2.03919302088843 0.0419126452918771 TMEM88 other 1 1 1 -0.89050874112253 -2.03919302088843 7.37318604866571e-28 316.579976439866 30.4570970035124 10.3942925487402 3.3146354592532e-23 -381.47078944714 106.985401004124 -3.56563405723397 0.000394950541112264 EVPL other 9.87859466800231e-24 1 4.68954624775142e-19 10.3942925487402 -3.56563405723397 1.39217576687442e-74 680.939054417989 32.274841849025 21.0981376021386 1.39606677028801e-72 -97.7163180015579 112.924119746329 -0.865327250024762 0.387242041936348 SRP68 other 2.1595430495756e-70 1 2.16934815435054e-68 21.0981376021386 -0.865327250024762 0.135239772865037 20.3610375706701 10.1603820252368 2.00396378011147 0.0455757001518104 12.8012498923773 30.7018356459373 0.416953892920445 0.676878757122589 MGAT5B other 1 1 1 2.00396378011147 0.416953892920445 0.367554937651141 -11.7683241042704 8.98279276567043 -1.31009635992555 0.190723361543341 7.19848594612036 26.5162034427157 0.271474985537489 0.786130065791236 TMC8 other 1 1 1 -1.31009635992555 0.271474985537489 1.25136355063911e-17 494.01680114794 55.2279665074943 8.94504781523875 5.9830492370555e-18 589.627839266118 162.972611905587 3.61795661474518 0.00032492995726307 TK1 other 1.39864904054933e-13 1 8.04061986967889e-14 8.94504781523875 3.61795661474518 1.26526616353237e-63 216.412760099454 11.1008936277854 19.4950755638064 1.22672517407491e-63 -78.6418993977105 88.4957351978212 -0.888651856746727 0.374609968884575 TMEM68 other 1.95129347739962e-59 1 1.89860255191574e-59 19.4950755638064 -0.888651856746727 2.20126883854099e-09 1.27964758525034 0.202887461209765 6.30717924912723 6.08820216977559e-10 8.98458508131015 4.0736939320052 2.20551303835624 0.0278557073719436 GSDMA other 1.77202141502549e-05 1 6.83644221644101e-06 6.30717924912723 2.20551303835624 0.151537431880253 6.80662132711222 8.16036042341367 0.83410792831928 0.404593829670461 73.5396096368727 38.4199577028165 1.91409918266208 0.0561426751523605 KRT24 other 1 1 1 0.83410792831928 1.91409918266208 7.19622596031282e-73 149.187809280371 8.19929557324969 18.1951983493678 5.79714517030987e-58 -213.35983826456 35.2584749970032 -6.05130648114231 2.70031558526413e-09 TMEM99 other 1.11541502384849e-68 3.74614781143693e-05 8.94963271392438e-54 18.1951983493678 -6.05130648114231 2.77375442913566e-40 95.9440744088704 28.4206432749456 3.37585864896487 0.0007889980575004 -765.182059257799 64.9341724688587 -11.7839656711536 1.13022869667248e-28 GHDC other 4.06743349488454e-36 1.76688652150809e-24 1 3.37585864896487 -11.7839656711536 2.50628855079884e-30 386.867603198938 36.9567140141885 10.4681277412925 2.03237089716277e-23 -438.666653064371 163.64032001909 -2.68067584451801 0.00757835584635071 FAM234A other 3.43887852055109e-26 1 2.88068250963851e-19 10.4681277412925 -2.68067584451801 1.55998153545307e-15 185.691629586049 21.8810868537223 8.4863988168147 2.04567392098785e-16 205.327985092862 100.074044553687 2.0517606339245 0.0406728570612018 ZNF598 other 1.63829260853282e-11 1 2.68085567345457e-12 8.4863988168147 2.0517606339245 3.17499908605718e-12 93.1310235572387 15.652403320215 5.94995041029644 4.82629221393708e-09 -167.281651725772 71.1762490001691 -2.3502453989304 0.0191199420480682 RAB26 other 2.94385915259222e-08 1 5.22928761380083e-05 5.94995041029644 -2.3502453989304 2.03575218487895e-20 210.657599611454 23.9726712722664 8.7874061767643 2.03830094389409e-17 -172.785393884194 110.932518255704 -1.55757208617509 0.119920571387596 MLST8 essential 2.43007738309e-16 1 2.71623983783327e-13 8.7874061767643 -1.55757208617509 3.99467613854254e-17 189.185195059216 25.1364274689943 7.52633584436672 2.1886582860984e-13 -259.039548781468 115.551865644867 -2.2417599866158 0.0253806824438802 E4F1 essential 4.40652724842627e-13 1 2.70474390996041e-09 7.52633584436672 -2.2417599866158 1.93311622017963e-12 16.8282749830995 2.78957150757606 6.03256626954945 2.99072559853853e-09 -29.722403959809 12.8236278782171 -2.31778434637027 0.0208325031004326 DNASE1L2 other 1.8068837310019e-08 1 3.26527420848436e-05 6.03256626954945 -2.31778434637027 8.5226257983516e-16 310.34953983943 44.9445210791485 6.90516958213651 1.40584671870464e-11 -531.85424313918 205.479588672153 -2.58835559568773 0.00990185055037264 ECI1 other 9.03227882109303e-12 1 1.66086731347767e-07 6.90516958213651 -2.58835559568773 2.5699158249076e-14 126.400072112066 17.5160974596776 7.21622338554814 1.84871194771367e-12 -102.510842502599 81.5751533355044 -1.2566429643226 0.209433396564576 CASKIN1 other 2.58430735352708e-10 1 2.23583222956491e-08 7.21622338554814 -1.2566429643226 2.48918289424758e-07 282.096512989825 100.193066703429 2.81552928033263 0.00504660007186351 -1677.3793243682 460.399512392177 -3.64331255620309 0.000294974721126519 ABCA3 other 0.0017484020649195 1 1 2.81552928033263 -3.64331255620309 2.02432456922924e-23 191.988706319872 18.094301544867 10.6104513536382 4.89523817955417e-24 174.414154005248 82.7538609347144 2.10762557825363 0.0355194888982945 KCTD5 other 2.55247084934115e-19 1 6.97081916768513e-20 10.6104513536382 2.10762557825363 3.17944308704427e-11 1292.86643895648 301.588427242281 4.28685692875694 2.14519266758497e-05 -5283.04487562225 1364.10267966997 -3.87290850927765 0.000120681234005824 SRRM2 essential 2.81293586979786e-07 1 0.18819775272723 4.28685692875694 -3.87290850927765 1.75992207900987e-20 17.9290520454202 4.57037479529675 3.92288441286489 9.8718656193646e-05 -155.457712324289 21.0905869083526 -7.37095240638953 6.35437679117747e-13 ZNF597 other 2.1036348610405e-16 9.35364263661323e-09 0.816502005377646 3.92288441286489 -7.37095240638953 0.943720127604267 1.04300029963045 4.17776788103591 0.249654918446985 0.802948638908042 -2.70635178152077 19.4135743380788 -0.139405126247792 0.889181710555027 NLRC3 other 1 1 1 0.249654918446985 -0.139405126247792 5.39880951644159e-37 120.889194673023 13.3334208008259 9.06663012282147 2.54389231461091e-18 -232.648191778898 35.2324069760671 -6.60324433516374 1.00012798525745e-10 SDHAF2 other 7.79210177508015e-33 1.42978296772406e-06 3.43272828933596e-14 9.06663012282147 -6.60324433516374 4.54807061092334e-29 1070.20118870339 155.734938612822 6.87194022250879 1.82487713807507e-11 -2739.20414948946 410.487660042777 -6.67304870797823 6.45426265547662e-11 DDB1 essential 6.17218662608406e-25 9.25347636915682e-07 2.14824536694197e-07 6.87194022250879 -6.67304870797823 2.87759387136804e-17 159.973577740532 34.7555172809721 4.60282540027434 5.24211385974203e-06 -481.241278125711 89.8702116284554 -5.35484750069663 1.28646571433543e-07 VPS37C other 3.18607193437869e-13 0.00169414669920833 0.048201236940328 4.60282540027434 -5.35484750069663 0.00639097020994077 3.96153242958731 1.33504726160044 2.96733497272469 0.00314223914076954 0.201980793606455 3.57229060101695 0.0565409750116511 0.954932572740695 VWCE other 1 1 1 2.96733497272469 0.0565409750116511 0.00489613137376179 36.3950844157652 13.8336180046135 2.63091581707892 0.00876863248283403 -27.8862418447902 34.2636917808787 -0.813871488896373 0.416091814040295 RAB3IL1 other 1 1 1 2.63091581707892 -0.813871488896373 8.77220403867492e-12 3918.30263543384 949.911757626589 4.12491223945259 4.31881766386576e-05 -9476.45564510195 2352.78172864798 -4.02776659207889 6.47232792714834e-05 BEST1 other 7.97568791196324e-08 0.740045975190141 0.369086157553968 4.12491223945259 -4.02776659207889 3.57320738301483e-12 4280.303807418 1052.54803788089 4.06661135964455 5.50950182070708e-05 -10996.6374411261 2596.55607210778 -4.23508568108813 2.7021081862494e-05 FTH1 other 3.30450218781212e-08 0.317173458901955 0.466544614177476 4.06661135964455 -4.23508568108813 1.13462542429614e-09 339.504905690783 88.0819001948186 3.85442304196288 0.00013060776024977 -725.598829079647 221.073788158273 -3.28215676369634 0.00109977657503018 BSCL2 other 9.25740883683222e-06 1 1 3.85442304196288 -3.28215676369634 4.46500175516004e-23 242.127433145839 36.4240884739779 6.6474534652753 7.5643476926633e-11 -465.297708917853 93.0605638973258 -4.99994508341062 7.85698693833769e-07 POLR2G essential 5.6022377021993e-19 0.0100278724294004 8.74211662841098e-07 6.6474534652753 -4.99994508341062 0.00116587335693649 405.118124104875 163.454122835987 2.47848213967278 0.01350924756362 -643.564221172589 421.677103541493 -1.52620148394958 0.127565342362006 SLC3A2 other 1 1 1 2.47848213967278 -1.52620148394958 0.0233207835725264 -32.9303812392467 42.375432178608 -0.777110215665733 0.437444420895382 -295.994557389675 108.273637448427 -2.73376386316256 0.00647325704480526 HRASLS5 other 1 1 1 -0.777110215665733 -2.73376386316256 1.06910428075251e-11 121.071544480897 21.369644577155 5.66558531396109 2.40028167858498e-08 -95.198758090268 51.1959894031039 -1.85949640196809 0.0635075870599167 C11orf84 other 9.6743246365295e-08 1 0.000252965686106071 5.66558531396109 -1.85949640196809 5.34348431822532e-11 128.447145594325 22.1669153379291 5.79454306727751 1.22026284317316e-08 -107.960620695501 67.8181305457519 -1.59191384113232 0.112042430533739 ATG16L2 other 4.67180833942439e-07 1 0.000130214247995008 5.79454306727751 -1.59191384113232 2.16370294831241e-56 329.731483868729 19.9842243212282 16.4995888040785 1.77706460307585e-49 -125.771368949018 71.736108500032 -1.75325051189474 0.0801493542721718 C2CD3 other 3.30808543767484e-52 1 2.72192985253128e-45 16.4995888040785 -1.75325051189474 4.98530950965889e-05 -8.20830343567311 43.9507074188814 -0.186761577178774 0.851917329659525 -362.956702218706 86.7693742321105 -4.18300472293124 3.35425751382591e-05 TRANK1 other 0.281869399676114 0.390972255811548 1 -0.186761577178774 -4.18300472293124 7.20976301415861e-06 678.614897202327 243.525761931304 2.7866246750262 0.00551130491529121 -1166.47313049757 472.679328599198 -2.46778959840376 0.0139005150832228 RPSA essential 0.0443688815891321 1 1 2.7866246750262 -2.46778959840376 0.00363440385273886 -9.04194237139876 19.5215437937444 -0.463177629132806 0.643421610949151 -120.423064016852 37.6082497455442 -3.20203851100833 0.00144404038019332 ENTPD3 other 1 1 1 -0.463177629132806 -3.20203851100833 1.61373506659245e-05 1235.88446168051 415.665371252708 2.97326779461054 0.00307704069167753 -1602.7696567881 807.001829236081 -1.98607933553918 0.0475259472823214 CTNNB1 og 0.0963561208262353 1 1 2.97326779461054 -1.98607933553918 1.81410020295291e-23 4.7190196784732 8.13016754467336 0.580433263219152 0.561863270560844 -148.020086864269 15.8636406221908 -9.33077660982881 2.65833346733306e-19 ULK4 other 2.28975727616717e-19 4.08293437247684e-15 1 0.580433263219152 -9.33077660982881 1.03444319732222e-119 318.162038035039 10.1922279782543 31.2161422128564 9.24479040752878e-119 4.35238203355686 86.6986001210914 0.0502012953782173 0.959982352761933 FADD other 1.61859327085008e-115 1 1.44653235506603e-114 31.2161422128564 0.0502012953782173 2.79047359664861e-05 -151.389972507262 112.675762187324 -1.34358951355994 0.179669423680329 -1322.38158819843 286.10691481693 -4.62198401966125 4.80409049749307e-06 LTBP3 other 0.162461372796882 0.0590614885761799 1 -1.34358951355994 -4.62198401966125 0.00415845789795702 -3.41376587619573 2.66902281546573 -1.27903210733702 0.201454035447358 -21.5288737204801 6.46737270101513 -3.32884383129812 0.000933643587290099 NAALADL1 other 1 1 1 -1.27903210733702 -3.32884383129812 0.000132003030817977 52.2477459610927 16.0954905080093 3.24611082433887 0.0012447218493446 -49.3341030185364 38.4496845020196 -1.28308212817572 0.200030500475174 SAC3D1 other 0.707008233061086 1 1 3.24611082433887 -1.28308212817572 0.0232760172619235 25.7578134947727 14.2620663599421 1.8060365759564 0.0714852054192254 -40.8616146883342 34.0052728045944 -1.20162584558985 0.23005028912927 BATF2 other 1 1 1 1.8060365759564 -1.20162584558985 6.40004121152833e-12 94.7460434565319 75.4012250649156 1.25655840969376 0.20946503994372 -1082.63802501006 176.063941997751 -6.14911839826855 1.53115449805207e-09 SF1 essential 5.85795772091188e-08 2.13611364023244e-05 1 1.25655840969376 -6.14911839826855 5.1508240403668e-14 77.4102540189698 16.436850642137 4.70955511517051 3.17330869816828e-06 -157.223317517187 38.4553354702407 -4.08846563408236 5.01508817061456e-05 MAP4K2 other 5.12094926093268e-10 0.578540571362095 0.0295815836843247 4.70955511517051 -4.08846563408236 0.248421135057353 19.6406200022481 14.8264801702546 1.32469876711884 0.185838754150747 -13.8706164629989 35.1130888055432 -0.39502695247959 0.692981032215095 CCDC88B other 1 1 1 1.32469876711884 -0.39502695247959 7.30192450467077e-08 63.9931433969285 85.9476621985616 0.744559441873911 0.456860197363525 -747.096646974699 182.521562489058 -4.09319664365401 4.90150174544117e-05 SCARA3 other 0.000533332565821153 0.565927391528638 1 0.744559441873911 -4.09319664365401 4.67769039496035e-06 104.9687462902 25.2722656501026 4.15351546804328 3.80311047907911e-05 19.9924246275287 52.006672271073 0.384420378279978 0.700817678620536 PBK other 0.0292963749436367 1 0.326573096838524 4.15351546804328 0.384420378279978 0.333109875678148 84.1119539106299 56.6759271030633 1.48408606987011 0.138367381267015 106.011864759408 116.798541772227 0.907647160237201 0.364468038751456 SCARA5 other 1 1 1 1.48408606987011 0.907647160237201 0.364765693510073 -0.884058910742601 1.25955309740992 -0.701883003233871 0.483053411214086 1.37133275072731 2.596853320514 0.528074781850165 0.597663564876079 PNOC other 1 1 1 -0.701883003233871 0.528074781850165 7.7548749575342e-25 359.003568175235 46.4689603556286 7.72566387170636 5.49637138322122e-14 -809.5849624502 148.077244159808 -5.46731516408069 7.00882900015885e-08 COPS6 essential 1.00014622327319e-20 0.000932384521891132 6.88805261745284e-10 7.72566387170636 -5.46731516408069 3.42685608340467e-47 378.649049698171 57.1331399263138 6.62748538215342 8.18234562019188e-11 -870.560677824278 104.791750807101 -8.30753061304214 7.70550673547088e-16 PAFAH1B2 other 5.14576709484046e-43 1.16407090252759e-11 9.44897272219758e-07 6.62748538215342 -8.30753061304214 2.1844326674106e-10 70.5572434685047 12.489826265195 5.64917733604703 2.60628442379123e-08 -133.23837296433 62.3494789898857 -2.13696048664567 0.0330482198864926 ANKS3 other 1.85676776729901e-06 1 0.000274435929005737 5.64917733604703 -2.13696048664567 3.32493194838322e-17 158.217091334148 23.5447875008888 6.71983517915271 4.60804533671543e-11 -469.572149826191 117.592552279382 -3.99321335173131 7.4158421520862e-05 NUDT16L1 other 3.67504728254798e-13 0.844145312171972 5.35593109486434e-07 6.71983517915271 -3.99321335173131 1.76906770399248e-12 24.7031160281123 4.28308540408268 5.76759828430342 1.38956169114827e-08 -51.5719104120168 17.3432261123449 -2.97360537641309 0.00308141977850519 KIAA1586 other 1.65637809124816e-08 1 0.000147946633256557 5.76759828430342 -2.97360537641309 5.89025017930022e-23 182.352511780545 17.9171889300327 10.177517940601 2.22943005814253e-22 -241.890550319758 107.246868296565 -2.2554556059471 0.0245034887547206 RAB4A other 7.37753834957353e-19 1 3.12967391562049e-18 10.177517940601 -2.2554556059471 6.18934585524443e-15 621.893825781474 75.3196082609917 8.25673207999882 1.16968658088909e-15 70.0354892446208 195.65794920006 0.357948601275635 0.720522431838108 SETD5 other 6.37626410007281e-11 1 1.51205384311533e-11 8.25673207999882 0.357948601275635 6.50761134173761e-08 131.179185998121 24.6596323640458 5.31959211968558 1.52290504184417e-07 462.42511603863 122.809033239237 3.76539985570774 0.000184428001942815 VASN other 0.000477268215803036 1 0.00153767722075006 5.31959211968558 3.76539985570774 2.28283783232927e-07 70.6207852656929 12.7981935454375 5.51802760404957 5.39239170206021e-08 33.4026822152573 46.5806585874995 0.717093386571852 0.473635383403959 FAM83B other 0.00160757440152627 1 0.000559191019503644 5.51802760404957 0.717093386571852 3.04064158223859e-18 32.7054876591904 4.34020590866191 7.53546913383046 2.07504987819703e-13 -22.8357134250457 10.2343594878393 -2.2312791975091 0.0260738897042694 THAP9 other 3.4523444524737e-14 1 2.56600667937844e-09 7.53546913383046 -2.2312791975091 3.76560432091667e-18 574.164824667495 63.8011113450452 8.9992919020224 3.8060756636408e-18 -663.585331711926 379.208358549134 -1.7499227449807 0.0806964859041622 RNF187 other 4.26642969559859e-14 1 5.1252614886587e-14 8.9992919020224 -1.7499227449807 3.26483579203662e-18 210.721054729847 26.6227123097766 7.91508589650589 2.54694185207897e-14 -246.115216930178 111.289121985131 -2.21149392267701 0.0275764921403381 HOOK3 other 3.70395620606554e-14 1 3.21424061732366e-10 7.91508589650589 -2.21149392267701 8.22405586603501e-18 190.82655289734 39.7023896679935 4.80642486492891 1.99354018830536e-06 -501.167824202679 87.6301040735506 -5.71912848331247 1.77291762884051e-08 MAPK1IP1L other 9.24301638783675e-14 0.00024044308882335 0.0188369612392974 4.80642486492891 -5.71912848331247 0.000467174511572145 937.983522111445 237.911045984099 3.94258080044814 9.12187594427023e-05 800.534515874554 611.193186417133 1.30978966007026 0.190823942117937 DDIT4 other 1 1 0.756294734539444 3.94258080044814 1.30978966007026 5.89207202065233e-13 329.900463791058 55.057381363108 5.99193887583097 3.77896382315193e-09 -111.349094148418 99.9340470566183 -1.11422580619929 0.265675264622181 RBPJ other 5.61160939246928e-09 1 4.11037895044235e-05 5.99193887583097 -1.11422580619929 3.15790337005593e-19 143.96301857388 31.7237755773965 4.53801654921728 7.01264401346985e-06 -416.128095785509 75.5132965827766 -5.51065990516459 5.55593533797127e-08 LMBRD1 other 3.67390478072307e-15 0.000741606248912405 0.0639202501827777 4.53801654921728 -5.51065990516459 2.17819962889655e-34 25.0266446105225 5.76337592957037 4.34235852673037 1.68321435621924e-05 -91.1152163506223 10.44612603559 -8.72239297517498 3.36224103965584e-17 ZCCHC4 other 3.09369693292177e-30 5.12170177570774e-13 0.148812981233343 4.34235852673037 -8.72239297517498 0.274815722102448 -2.83707806183703 4.31314459501471 -0.657774855291479 0.510961045608797 -16.4090251406333 10.2585613164181 -1.59954448138569 0.110280253720355 PTGDR other 1 1 1 -0.657774855291479 -1.59954448138569 9.6787569522509e-11 12.9057227746559 39.1010012679651 0.330061184014472 0.741484396756732 -561.633562811576 89.245938704184 -6.29309939439571 6.534613722066e-10 TTC39C other 8.34695999562117e-07 9.19420150694687e-06 1 0.330061184014472 -6.29309939439571 3.09263288993279e-08 3.22605224445083 4.18036119623856 0.77171614915802 0.440631105104789 -36.6346404938524 7.63535729898619 -4.79802569274874 2.09343072160034e-06 GLYCTK other 0.000232225803705053 0.0261930051886635 1 0.77171614915802 -4.79802569274874 0.706322019068646 26.2409218303896 31.847347336685 0.823959419695926 0.410323708888475 -16.5818082997913 199.195176816299 -0.0832440251055043 0.933688128837173 GNG4 other 1 1 1 0.823959419695926 -0.0832440251055043 4.02489142388371e-16 96.374589044416 26.3156177712267 3.66225827880017 0.000274758329532107 -429.959396124725 70.7273775200639 -6.07910841884041 2.29414489326141e-09 UBTD2 other 4.30703631269796e-12 3.18725550020808e-05 1 3.66225827880017 -6.07910841884041 1.55978976621593e-12 166.474059158113 30.4357569929398 5.46968682910467 6.91526106995365e-08 -323.314099686084 94.3490459138726 -3.42678716625523 0.000657472262144834 POLR2J3 other 1.4627708427573e-08 1 0.00071310172153362 5.46968682910467 -3.42678716625523 3.10627251625542e-31 292.542663098488 24.5205121171847 11.9305282736516 2.89675025427088e-29 62.1759816192748 56.1684994023669 1.10695465039707 0.268810068465665 NKIRAS2 other 4.30125555325888e-27 1 4.24258042240513e-25 11.9305282736516 1.10695465039707 7.87252994850787e-45 395.029891226528 37.2899735821672 10.5934612787025 6.14473358467749e-24 -521.965209770354 85.4191726850737 -6.11063293360091 1.91024042681554e-09 DNAJC7 other 1.17489636951531e-40 2.6594367222126e-05 8.74457036435454e-20 10.5934612787025 -6.11063293360091 1.7957660787296e-17 821.020518210832 90.2253433369886 9.09966632262454 1.72091397077247e-18 43.3626438644751 548.59605385838 0.0790429379859687 0.937027643991368 IRF2BP2 other 1.99743060937093e-13 1 2.32701987127854e-14 9.09966632262454 0.0790429379859687 0.000773317737976448 262.772448192488 92.8016660201852 2.8315488230064 0.0048100714178964 603.784402356744 167.342293251624 3.60808012502175 0.00033797719112782 NT5DC2 other 1 1 1 2.8315488230064 3.60808012502175 0.270500060516303 -29.53000672045 46.8717882780631 -0.630016643386117 0.528949200365129 -196.110419035207 121.176521104666 -1.61838627852516 0.106161120362387 FOXI1 other 1 1 1 -0.630016643386117 -1.61838627852516 1.04991805820437e-12 17.6560964933609 10.3642242746164 1.70356179348641 0.0890525224524806 -105.549153089182 18.676110662694 -5.65155963120414 2.60651185511706e-08 SMIM4 other 9.91437622362384e-09 0.000351592384136741 1 1.70356179348641 -5.65155963120414 2.31087296736731e-15 90.3263932117353 10.6677582276057 8.46723287916212 2.34789262737443e-16 42.8196850852002 64.4398412722041 0.66449085286109 0.506657762448501 COA6 other 2.41347572711841e-11 1 3.07503497407229e-12 8.46723287916212 0.66449085286109 9.98553310422857e-05 -245.558205635499 97.2527541101982 -2.52494860307251 0.011862712310262 -953.673851452414 229.722047498781 -4.15142500180561 3.85076639265986e-05 KIF5C other 0.542713724214823 0.447343531835296 1 -2.52494860307251 -4.15142500180561 6.49733473673246e-19 96.5076698380092 16.1175364080972 5.9877432502355 3.9439019128815e-09 -215.256173814587 40.0126627907594 -5.37970129456864 1.12476806045046e-07 MGAT2 other 7.49077721797886e-15 0.00148581860785506 4.28544381853704e-05 5.9877432502355 -5.37970129456864 0.0185405329685264 -203.324500081809 138.759416181134 -1.46530236057201 0.143432525510461 -1442.05108501417 538.202395821543 -2.67938436582569 0.00760548515662747 BMI1 other 1 1 1 -1.46530236057201 -2.67938436582569 1.24253673586024e-43 106.153039189616 13.0129661294245 8.15748217077014 2.50520871071354e-15 -170.556681593905 29.1003356444316 -5.86098674867145 8.10138827250591e-09 THAP11 essential 1.8466580968355e-39 0.000111102438769146 3.22119736023548e-11 8.15748217077014 -5.86098674867145 4.75045890022453e-10 149.374294483734 43.3655442796974 3.44453867615048 0.00061716721490742 -439.460638848823 102.438985855551 -4.28997451681633 2.12286945889388e-05 MMADHC other 3.9628328145673e-06 0.251177914376324 1 3.44453867615048 -4.28997451681633 2.34111796221136e-39 237.826444880365 41.5772417200483 5.72011117239858 1.75700236652483e-08 -705.355529188588 78.6834785306577 -8.96446804793663 4.96742910298289e-18 PDHB other 3.41850044842103e-35 7.59718607010203e-14 0.000186242250851632 5.72011117239858 -8.96446804793663 1.65521645921043e-20 40.7122822241474 16.6424366435183 2.44629335813056 0.0147477862417474 -229.494075525252 31.4845912949539 -7.28909177747637 1.10054468799292e-12 PXK other 1.97963888521567e-16 1.616480037724e-08 1 2.44629335813056 -7.28909177747637 0.446501788927079 2.59715379736581 2.12341687225048 1.2231012342919 0.221832970194593 0.0798911932833462 8.3212865200039 0.00960082231170533 0.992343368893501 HIST1H1E other 1 1 1 1.2231012342919 0.00960082231170533 1.26907913089156e-15 411.240160823097 51.5939816137551 7.97070022433506 1.16458604163006e-14 -838.838171103892 412.434327263839 -2.03387088720013 0.0425151577464555 PCMTD1 other 1.33735558813353e-11 1 1.48053823472429e-10 7.97070022433506 -2.03387088720013 6.15745373415992e-14 113.390785601423 36.137829907027 3.13773090119543 0.00179464218945371 -342.552612716802 68.4427890216693 -5.0049481853866 7.55340440221786e-07 KCTD6 other 6.10757835891322e-10 0.00964947412383332 1 3.13773090119543 -5.0049481853866 3.36909775110518e-12 61.5904940773969 9.69516678441854 6.35270082990023 4.46179109952425e-10 -83.0814326119901 37.1089585653646 -2.23885109752268 0.025567652912453 MPLKIP other 3.12012142729851e-08 1 5.03602361403302e-06 6.35270082990023 -2.23885109752268 4.94514029313058e-08 149.90634808968 72.7816784658669 2.05967148943924 0.039904311193513 -534.432298829827 137.843945712791 -3.87708213129186 0.000118611360577218 ACOX2 other 0.000366335992915113 1 1 2.05967148943924 -3.87708213129186 0.0018117788585582 24.9690263665298 41.5179576254456 0.601403050501376 0.547821173270339 265.940036301385 78.6060478366624 3.38320070300429 0.000767852788055396 FAM107A other 1 1 1 0.601403050501376 3.38320070300429 2.56436780527101e-16 10.3720670912909 21.1855357235148 0.489582478661536 0.624626371174783 -344.221219693033 44.5569798268971 -7.72541633275695 5.38679210823467e-14 IRF2 other 2.7620805630574e-12 8.01770137389648e-10 1 0.489582478661536 -7.72541633275695 7.6536578043715e-07 -96.9662163005403 30.181506792119 -3.21276922880007 0.0013924225617562 -310.455710227538 58.9015971597444 -5.27075198632671 1.96224838561749e-07 CX3CR1 other 0.00516774974951164 0.0025619114922622 1 -3.21276922880007 -5.27075198632671 0.196079948198079 90.2500257396632 179.700033496379 0.502225981730169 0.615711790156997 625.886796956164 350.698825459573 1.78468461117875 0.0748696323299205 XIRP1 other 1 1 1 0.502225981730169 1.78468461117875 4.14313430596627e-19 -6.24081806163439 162.277157345555 -0.0384577728850964 0.969336859626954 -2959.55659424234 334.235702411744 -8.85469916255826 1.19459594558713e-17 DEGS2 other 4.80727873521266e-15 1.82378963012787e-13 1 -0.0384577728850964 -8.85469916255826 2.34116566777848e-11 457.027878453155 168.257372941811 2.71624280388123 0.00681321219642223 -1430.37665414446 314.95521017797 -4.54152402602327 6.88548166357757e-06 ARF4 essential 2.08387156088963e-07 0.0839822198506556 1 2.71624280388123 -4.54152402602327 5.34637759031011e-20 1026.79042787651 235.388091535363 4.3621171367637 1.54083463955511e-05 -3034.61954573388 455.401237672775 -6.66361725594251 6.55104624029632e-11 SEPT2 other 6.3306457046862e-16 9.39157989008881e-07 0.136641215835747 4.3621171367637 -6.66361725594251 0.429635134360825 -45.1929975249162 50.6206847303756 -0.892777285918409 0.37237339197508 -183.696979630999 173.45159835404 -1.05906766714277 0.290041580887989 FILIP1L other 1 1 1 -0.892777285918409 -1.05906766714277 2.57224513176869e-13 270.29087938436 35.1111054101834 7.69815920708569 6.58358507866118e-14 81.2029686928539 77.3848990902308 1.04933869072015 0.294489930672837 MFSD2A other 2.49121941011797e-09 1 8.23211478235794e-10 7.69815920708569 1.04933869072015 1.45274255088662e-06 134.380511633607 28.1222191809431 4.77844620899157 2.27583749824787e-06 -19.0097789675425 54.4733450227974 -0.34897396074331 0.72724388774785 DTYMK essential 0.0095532350146304 1 0.0214474925834879 4.77844620899157 -0.34897396074331 8.72156536075649e-08 1185.61936543504 205.431807851607 5.77135243969361 1.31937242966128e-08 1632.45916254897 721.392093107868 2.26292910352827 0.0240319987374023 TAP1 other 0.000633098429537313 1 0.000140592326104706 5.77135243969361 2.26292910352827 3.04702674544611e-08 45.6373819978423 22.0624867226669 2.06855113711886 0.039060132996368 -193.117344313749 42.7355125700438 -4.51889617556892 7.63114632854289e-06 ING5 other 0.000228953589652821 0.0928100016477386 1 2.06855113711886 -4.51889617556892 7.88688512154763e-09 125.363095298412 33.9700099067424 3.69040502615601 0.000246394768378005 -220.637713144598 65.721186039536 -3.35717789712239 0.00084236932779371 ATG4B other 6.14151744414914e-05 1 1 3.69040502615601 -3.35717789712239 6.50261093293401e-05 1.24600594953945 23.0285286942725 0.0541070585134409 0.956869732699324 -194.112083007932 47.7743106052834 -4.06310589412178 5.55569784222937e-05 BDKRB2 other 0.362455533401742 0.638849694877955 1 0.0541070585134409 -4.06310589412178 2.49430304567189e-11 46.7916616347842 9.39268794906258 4.98171150671029 8.47024948511089e-07 -23.7614605588834 20.5179437589277 -1.15808196172408 0.247336899314024 MLKL other 2.21793426821145e-07 1 0.00818734315230819 4.98171150671029 -1.15808196172408 1.99731035349598e-42 360.867510819018 38.8291638674901 9.29372345102584 3.53499214303039e-19 -348.964595487446 84.8207248830047 -4.11414304662901 4.48581062793067e-05 RFWD3 other 2.955420130068e-38 0.519277438289254 4.81642679487891e-15 9.29372345102584 -4.11414304662901 0.00616515296598322 -14.0641515976285 71.6355019185784 -0.196329350963631 0.844425440571503 -423.019326294681 147.335451584539 -2.87113061890578 0.00424880110943511 RHOH other 1 1 1 -0.196329350963631 -2.87113061890578 0.21986586707754 9.0062782092275 5.52638649163259 1.62968663571825 0.103743429510662 12.4519055722737 10.7194223012753 1.16162095515094 0.245896088033743 KLHL30 other 1 1 1 1.62968663571825 1.16162095515094 3.73636038013577e-35 216.523362586322 19.2758939734971 11.2328571055654 1.88423393365162e-26 -477.103450752514 105.112559136066 -4.53897664250485 6.97663541486331e-06 COG7 other 5.33664353094792e-31 0.0850730922488433 2.72252961073322e-22 11.2328571055654 -4.53897664250485 2.08818068353439e-60 211.335194826833 13.6483770574631 15.4842728873227 5.08507001115997e-45 -132.968660638627 40.6499355752606 -3.27106694652552 0.00113980402640917 CDC40 essential 3.21036898286577e-56 1 7.74405311999551e-41 15.4842728873227 -3.27106694652552 1.44671464334116e-19 1148.18437133469 147.922769885618 7.76205294304945 4.33413129309551e-14 -787.32373322552 349.960131961809 -2.24975264699992 0.0248741571414954 STIP1 other 1.69844299128252e-15 1 5.44410231725727e-10 7.76205294304945 -2.24975264699992 0.0872790289450402 70.5575346061445 31.9632082115502 2.20746097009899 0.0277015990599532 70.1280842668765 176.369680759704 0.397619840126734 0.691067562067856 SCNN1B other 1 1 1 2.20746097009899 0.397619840126734 0.321670717205782 91.6098419316957 64.2159402976214 1.42659036848346 0.154286799034684 68.8080127445325 129.961094615059 0.52945085564522 0.59671441786275 HR other 1 1 1 1.42659036848346 0.52945085564522 0.00011689629897873 -143.016255812507 386.85227971318 -0.369692162389587 0.711757075418214 -3409.88570995759 854.207252443819 -3.99187164496928 7.46372329106854e-05 RAB31 other 0.629837258897397 0.849297073290689 1 -0.369692162389587 -3.99187164496928 5.15656525563269e-21 188.115207500899 29.8719268458502 6.29739114157719 6.33475193965936e-10 -133.17307158737 60.5192316799865 -2.20050829943715 0.0281990438780927 REEP4 other 6.2332560810088e-17 1 7.10505777552193e-06 6.29739114157719 -2.20050829943715 0.743282714554432 -93.0924914918166 125.501189371907 -0.741765810807963 0.458567370854452 -208.578596781384 483.303672430301 -0.431568408600215 0.666235729114698 TNXB other 1 1 1 -0.741765810807963 -0.431568408600215 0.0859990651695361 31.8120382747472 42.1341324534407 0.755018233967444 0.450572152525307 -98.0942541761701 85.0825436948863 -1.15293043574185 0.249456695517251 BMP1 other 1 1 1 0.755018233967444 -1.15293043574185 1.02117485300492e-13 374.669957449247 51.8650479444711 7.2239392866345 1.76726868654989e-12 -426.181226509432 314.542826742273 -1.35492273317246 0.176019403483951 ATXN2L other 1.00412123295974e-09 1 2.13874856446268e-08 7.2239392866345 -1.35492273317246 0.00233815362017089 -0.662535245761732 4.2783492672927 -0.154857680934726 0.876991703013452 -24.376044294034 8.64623128317358 -2.81926812916423 0.00499101682874041 PHYHIP other 1 1 1 -0.154857680934726 -2.81926812916423 2.5016182315339e-09 9.9296932746711 3.5736018440193 2.77862327928032 0.00564691657391927 -30.3659755540324 7.55220666225738 -4.02080834278387 6.61597293541776e-05 CCDC110 other 2.00554733622073e-05 0.7557815670643 1 2.77862327928032 -4.02080834278387 9.18923290729551e-35 125.730138792941 17.7579046454687 7.08023504479305 4.51808754580269e-12 -160.837876028387 35.8845609323008 -4.48209123505289 9.0369787839381e-06 POLR3D essential 1.30827108901166e-30 0.109410702137139 5.4108616448533e-08 7.08023504479305 -4.48209123505289 7.39128737474888e-11 265.824636812839 44.4355700059575 5.98224883302272 4.09826630703877e-09 -128.875073714539 113.615511393162 -1.13430879405693 0.257187669157757 FEN1 essential 6.42155047118183e-07 1 4.44907790292129e-05 5.98224883302272 -1.13430879405693 0.10635971500895 -4.83973289807833 64.8764829087509 -0.0745991872723039 0.940561349650948 -329.431089530391 158.907929719343 -2.07309408732603 0.0386389688081346 CAVIN2 other 1 1 1 -0.0745991872723039 -2.07309408732603 1.88057447197663e-06 -35.8127500367817 41.9031173341686 -0.854655985405157 0.3931213296185 -437.707524697072 88.3014666910152 -4.9569677730122 9.6049978074499e-07 MTCL1 other 0.0122632261317596 0.0122098732128303 1 -0.854655985405157 -4.9569677730122 1.35428668559312e-21 56.7930548383778 12.4983472254581 4.54404520964939 6.83010287578367e-06 -204.498965978571 30.2748758192767 -6.75474169404725 3.74840375273192e-11 HEXIM2 other 1.65453204378911e-17 5.3958272020576e-07 0.0623110285357745 4.54404520964939 -6.75474169404725 1.96434601877772e-48 444.257377634702 29.0496153319374 15.2930554349297 1.02281810587434e-41 -285.309729470456 122.425470012286 -2.33047689702007 0.0202889115640662 FNTA other 2.95712649666798e-44 1 1.5504899666949e-37 15.2930554349297 -2.33047689702007 2.98891916490644e-06 850.271999592977 320.315032631688 2.65448671767664 0.0081793947190702 -1554.00984312312 562.514447099739 -2.76261321133248 0.00593136805125839 SERINC2 other 0.0190962045445872 1 1 2.65448671767664 -2.76261321133248 0.730196338607591 305.763870621876 462.411727155645 0.661237275496167 0.508740622631201 -252.763004483006 1073.92418367735 -0.235363918910449 0.814015024523079 MYL1 other 1 1 1 0.661237275496167 -0.235363918910449 1.86455578942624e-27 210.805765311199 30.4111866369437 6.93184938252658 1.18247607061101e-11 -360.450389999583 63.6532806736473 -5.66271504288404 2.41726008002515e-08 TRAPPC11 essential 2.48787678983143e-23 0.000326450973807397 1.40052465803168e-07 6.93184938252658 -5.66271504288404 0.0945397692666819 28.4387926579291 13.7398856261095 2.06979835435366 0.0389625618528422 51.1825594583507 35.4400764044329 1.4442000314635 0.149282642730649 CHRM1 other 1 1 1 2.06979835435366 1.4442000314635 0.744691073482613 -1.15050605666929 6.47371573876549 -0.177719582245465 0.859009360313402 -9.06400093700264 13.0960500035509 -0.692117160101328 0.489159058597819 GFRA2 other 1 1 1 -0.177719582245465 -0.692117160101328 6.00038087146147e-22 60.9547013183345 10.4312204989652 5.84348699410402 8.81151652905582e-09 -113.739434180009 21.8426465248402 -5.20721855067611 2.72303070306608e-07 ING2 other 7.38586881468192e-18 0.00353721688328283 9.45035147741237e-05 5.84348699410402 -5.20721855067611 9.06630743939742e-24 45.7202165329954 13.6701103771593 3.34453894457114 0.000881098670720057 -225.716637872233 28.7084703173406 -7.86237076992202 2.04232498517144e-14 CDKN2AIP other 1.14987977253877e-19 3.05102929534761e-10 1 3.34453894457114 -7.86237076992202 9.02754901871372e-13 63.304753882198 9.7032526136331 6.52407562730611 1.57414505125391e-10 -53.5054107853492 30.2628783731049 -1.76802120821727 0.0776209241753522 SNRNP48 essential 8.54096412660505e-09 1 1.80176642566522e-06 6.52407562730611 -1.76802120821727 3.05690838743955e-19 105.418579500849 21.962844480571 4.79986003607616 2.08036962538023e-06 -320.695235010088 56.2134118307257 -5.70495944946004 1.95907833638621e-08 TMEM223 other 3.55824136297964e-15 0.000265200434396602 0.0196386892635894 4.79986003607616 -5.70495944946004 3.02135966544842e-38 393.840440973697 29.8113827501087 13.2110759260994 2.20032893768981e-33 -254.766797072193 132.445907209332 -1.92355356567969 0.0551112154822246 SLC20A2 other 4.39033772986311e-34 1 3.27232919613229e-29 13.2110759260994 -1.92355356567969 0.161108654639124 1.40230713231134 3.52571645838783 0.397736785944654 0.69097938756978 -9.45015602603863 7.46996158828176 -1.26508763323003 0.206378578360676 DYNLRB2 other 1 1 1 0.397736785944654 -1.26508763323003 4.65045004203424e-54 200.428060899448 18.6340720386889 10.7559990367811 1.43812790274685e-24 -381.163982942709 43.6622679903964 -8.72982555616548 3.22917562031163e-17 TMUB2 other 7.08170532400974e-50 4.91932613998273e-13 2.05407808349333e-20 10.7559990367811 -8.72982555616548 2.10057036812173e-17 967.299571749267 185.752786015982 5.20745660130257 2.72829735014432e-07 -1986.55016136673 416.450446280214 -4.7701957798601 2.37253567099343e-06 STAT3 other 2.33184316565193e-13 0.029628225459366 0.00271874830941882 5.20745660130257 -4.7701957798601 1.59230005299798e-48 79.3154807533922 5.07824191697883 15.618688918345 1.2699867660474e-45 -107.201585109902 32.650026480999 -3.28335369566358 0.00109245296671544 ZSWIM1 other 2.39784464980966e-44 1 1.93634882219247e-41 15.618688918345 -3.28335369566358 2.73262576817883e-88 613.379937923163 24.5930927872249 24.9411468183371 4.76892928514949e-87 -379.191167044841 304.835578725166 -1.243920308222 0.214172179818095 ADAM9 other 4.25852399712989e-84 1 7.43571454140509e-83 24.9411468183371 -1.243920308222 0.905023246408343 3.70191926438819 29.6117401302729 0.125015255709462 0.900558170948168 -56.4756660984144 143.5636114456 -0.393384267292652 0.694191529915259 GDNF other 1 1 1 0.125015255709462 -0.393384267292652 3.79092191131229e-10 21.8560247250463 7.35053614891877 2.97339191077392 0.00308244683880074 -162.20085410452 30.2258739769823 -5.36629161585334 1.21428613072516e-07 AXIN2 ts 3.17527619291517e-06 0.00160140054920034 1 2.97339191077392 -5.36629161585334 1.81602021970372e-12 722.634769742303 115.279944676259 6.26852113584614 7.49205430987571e-10 -480.322536310855 245.894837288355 -1.95336568106793 0.0512951804051613 NDUFS5 essential 1.69943172159874e-08 1 8.38136115645795e-06 6.26852113584614 -1.95336568106793 1.68162976519191e-07 5.89450041620993 3.74934823316585 1.57214002264942 0.116497352868522 -99.7310116189407 19.8072495332548 -5.03507624577055 6.49840077911153e-07 ZNF30 other 0.0011969840668636 0.00832185203773022 1 1.57214002264942 -5.03507624577055 0.158544711421762 8.31983283990018 4.48879795093615 1.85346565624881 0.0643588427158321 -5.4508365347852 22.5431371523422 -0.241795828945612 0.80902982570255 UGT3A2 other 1 1 1 1.85346565624881 -0.241795828945612 8.87905436540807e-26 629.37798818957 57.375051154812 10.969541212109 2.28711740206471e-25 -1540.1635131439 619.646361132555 -2.48555242110819 0.0132428359738784 FAM84B other 1.15995966229691e-21 1 3.28201347196286e-21 10.969541212109 -2.48555242110819 1.21742121212476e-09 66.4111596064382 114.150608774973 0.581785417696331 0.560959530764043 -1544.98956918452 271.811049346866 -5.68405726292942 2.177965347521e-08 LDLRAD4 other 9.91954803639255e-06 0.000294482694638315 1 0.581785417696331 -5.68405726292942 0.120781427532136 -29.1112103885297 19.8002275792294 -1.47024625207175 0.142073194671359 -82.8130619440921 42.8700544750967 -1.93172280646852 0.0539127547721202 SLC16A4 other 1 1 1 -1.47024625207175 -1.93172280646852 0.118461166926974 -56.5303829374501 28.8432801390111 -1.95991519220422 0.0505176934606999 54.145021580223 143.316118729324 0.377801339167471 0.70572608368631 IL7R other 1 1 1 -1.95991519220422 0.377801339167471 2.05912435237463e-32 166.976955354131 30.5967098772347 5.45735002306146 7.46128658853344e-08 -423.412201064171 67.2991550983229 -6.29149356252056 6.63343573371836e-10 TMEM208 other 2.88030314410163e-28 9.33191739019498e-06 0.000767990228557747 5.45735002306146 -6.29149356252056 0.726920991120753 -7.78452583919512 96.1131785120019 -0.0809933243256859 0.935477894192935 -175.018882568607 225.423521141377 -0.776400269512434 0.437859681308001 LRP1B other 1 1 1 -0.0809933243256859 -0.776400269512434 1.50631882762287e-15 477.412838855242 145.086280972025 3.29054432753221 0.00106483760025033 -1877.13509476779 323.535588593842 -5.80194315848293 1.11456759553676e-08 AHCYL1 essential 1.58299045594887e-11 0.000152060457059081 1 3.29054432753221 -5.80194315848293 2.82493724591727e-22 246.792071169382 26.1013125665412 9.45515941162824 9.73278229585009e-20 -366.485503159842 124.455755901027 -2.94470513241098 0.00337162581366055 DNAJC21 other 3.49727231044558e-18 1 1.33455910840696e-15 9.45515941162824 -2.94470513241098 3.29677561940674e-09 85.4742520127593 17.5583634187554 4.86800791020521 1.48446380013774e-06 -373.054537558118 109.091502254436 -3.4196480005201 0.000674679192596295 PKIG other 2.62588178085747e-05 1 0.0141306109135111 4.86800791020521 -3.4196480005201 4.35507251726614e-06 851.95837271681 454.277993976799 1.875411937212 0.0612794588640445 -3470.44013399166 985.101308090185 -3.52292714007232 0.00046324546637073 NPNT other 0.0273542104809486 1 1 1.875411937212 -3.52292714007232 0.022135643827177 26.935223279248 10.7777678312701 2.49914673436363 0.0127524509205703 -29.8266202962467 43.5601836144362 -0.684722097598365 0.493820323530623 FAM178B other 1 1 1 2.49914673436363 -0.684722097598365 0.00342645746769779 356.656919638666 121.86261660197 2.92671312650035 0.00357495022168211 -529.544306095491 463.914902127974 -1.1414686263935 0.254198324468046 SEMA4C other 1 1 1 2.92671312650035 -1.1414686263935 1.04465040050784e-06 21.8349303343462 19.8086877173519 1.10229060329016 0.270845260534084 -366.128326620305 74.5044778420806 -4.91417881481364 1.19666002881281e-06 CNNM3 other 0.00695946096818326 0.0151413393445684 1 1.10229060329016 -4.91417881481364 1.58207308773071e-08 87.2656116476148 40.179014885577 2.17192014030539 0.0302953462199103 -397.994885534929 92.2278914703825 -4.31534191218866 1.89503688982457e-05 GSTM4 other 0.000120854563171749 0.22490297808438 1 2.17192014030539 -4.31534191218866 2.88771178397995e-07 89.0695414864463 32.8681258155388 2.70990630820628 0.00694533412726133 -239.46013329742 71.0055986446804 -3.37241200508292 0.000798832135204057 TET2 other 0.00201706668111 1 1 2.70990630820628 -3.37241200508292 1.71463146063461e-06 18.9554626405061 16.2152001205953 1.16899344439359 0.242924922050431 -148.350330633335 35.3392116163386 -4.19789587396305 3.15303600844753e-05 CXXC4 other 0.011215404384011 0.368243075426587 1 1.16899344439359 -4.19789587396305 4.72533144097483e-13 27.9281000618469 19.5551322523583 1.42817239492097 0.153815036241978 -308.160604676211 44.8337220309948 -6.87341114492281 1.72011359152324e-11 TCTN2 other 4.51883445700423e-09 2.48883235557497e-07 1 1.42817239492097 -6.87341114492281 0.00488726602887003 13.5949383408473 6.89556453160242 1.97154827259488 0.0491740967062294 72.2230295420893 26.9553335137504 2.67935952286575 0.00760259667139531 SHOX2 other 1 1 1 1.97154827259488 2.67935952286575 5.21322125396822e-22 47.3537944620727 25.5434562531496 1.85385227405292 0.0643478566627189 -380.608303824778 47.5232064146847 -8.00889360249837 8.1585441857331e-15 PPIP5K1 other 6.42529519551583e-18 1.22329211520882e-10 1 1.85385227405292 -8.00889360249837 0.00098465356547723 -130.593526527809 86.3057665390079 -1.51314948890216 0.130823485447428 -727.76185866409 194.357711640514 -3.74444549959594 0.000200094295278219 TSPAN5 other 1 1 1 -1.51314948890216 -3.74444549959594 7.74535719020265e-41 88.289580954241 9.16918353564668 9.62894685344677 3.00765496963196e-20 -263.819930724776 34.6119796404413 -7.62221443169128 1.25865758502098e-13 ABHD15 other 1.13818023910028e-36 1.86696679586162e-09 4.14605237563765e-16 9.62894685344677 -7.62221443169128 1.15902976189498e-22 142.770381197225 16.5241685557621 8.64009470221969 6.47878121333984e-17 -115.427627182395 40.4866766160777 -2.85100277004603 0.00452609290306643 ZBTB5 other 1.44473059820209e-18 1 8.57077966712727e-13 8.64009470221969 -2.85100277004603 7.42241444170642e-29 271.225849697697 47.1555354314753 5.75172876770389 1.47622013976772e-08 -537.242928361713 104.498732943959 -5.14114299022007 3.81733817866217e-07 CHTF8 essential 1.00499491540705e-24 0.00493238266064939 0.000156996011864297 5.75172876770389 -5.14114299022007 3.07130494296139e-26 28.0013869165689 8.60713280892045 3.2532769666977 0.00121379396017523 -117.042556077473 14.8013452437268 -7.90756205940667 1.54489137519798e-14 ADAL other 4.03600182554556e-22 2.31038505160858e-10 1 3.2532769666977 -7.90756205940667 2.13129016347921e-45 54.9971377578353 13.8234867876615 3.97852861601636 7.90306435521245e-05 -269.032843119927 23.7717024889193 -11.3173569812819 9.77571374736613e-27 LCMT2 other 3.18649192341777e-41 1.52550013027648e-22 0.659273628511823 3.97852861601636 -11.3173569812819 2.71076614397185e-11 121.863749487613 28.0501510047175 4.34449531010074 1.66586590139558e-05 -118.493013750091 61.6269599548891 -1.92274637328902 0.0550336784921315 SNTB2 other 2.40580495277502e-07 1 0.147345838978439 4.34449531010074 -1.92274637328902 0.011247628267347 4.39990274912057 1.46331257382238 3.00680991049466 0.00276338137225873 1.0524738776977 5.55142569705465 0.189586231561399 0.849704881388135 IL12A other 1 1 1 3.00680991049466 0.189586231561399 1.37563592922356e-15 106.682915292119 13.5710985523532 7.86103754832877 2.11725178893624e-14 -92.571898636573 60.0535901527529 -1.5414881675035 0.123790373687605 ZNF507 other 1.44813194269364e-11 1 2.67472418496315e-10 7.86103754832877 -1.5414881675035 8.67569810801084e-43 43.7390476728416 16.6659911683798 2.62444922902799 0.00892145916287673 -381.96078250935 32.4892971408966 -11.7565111012681 1.31249560954509e-28 STX18 other 1.28556494564505e-38 2.05156188727993e-24 1 2.62444922902799 -11.7565111012681 0.0964292976048408 7.54562942621523 16.3920042998067 0.460323782754511 0.645466765113065 66.103584255468 31.9551770459176 2.06863458025851 0.0390496737767901 NSG1 other 1 1 1 0.460323782754511 2.06863458025851 4.19801376176249e-23 10.1954908591447 3.04686735963408 3.34622077554737 0.000875457002629224 -42.366729219995 5.93967547419949 -7.13283569178583 3.13178120343579e-12 ZBTB49 other 5.26934687376427e-19 4.57678505070106e-08 1 3.34622077554737 -7.13283569178583 5.3515922495988e-06 173.331467745741 44.2729133497509 3.91506803214964 0.000102060052302125 -505.165643430471 171.355117474667 -2.94806277673706 0.00333736620635244 GFM1 essential 0.0333243649382517 1 0.842913971963251 3.91506803214964 -2.94806277673706 7.47668328888634e-66 197.153202580842 20.1209602610737 9.7983992822777 5.66272770311449e-21 -361.002741612166 43.9558330765355 -8.21285177290556 1.60287322096562e-15 DDX19A essential 1.15462420030272e-61 2.41665195524986e-11 7.85816723361198e-17 9.7983992822777 -8.21285177290556 0.485420947350125 -7.94551500235645 9.02425977601209 -0.88046168877772 0.378999483715305 22.9420730602069 32.983350654702 0.695565265651273 0.486999242689439 ATOH8 other 1 1 1 -0.88046168877772 0.695565265651273 1.37251433160085e-33 75.9195552637842 9.53717173493821 7.96038462699194 1.02363428972312e-14 -86.7315555578205 19.3838053815618 -4.47443388181771 9.35484263315194e-06 ANKRD49 other 1.93730397905459e-29 0.113146821647973 1.30277936053062e-10 7.96038462699194 -4.47443388181771 0.426464980594684 -8.58791080717151 8.32768098132138 -1.03124877459089 0.302883274392025 -28.3044617034209 30.379156785846 -0.931706627111135 0.351902220884606 SFTPB other 1 1 1 -1.03124877459089 -0.931706627111135 5.10133958337144e-17 283.204343265424 32.0964494722022 8.82354116802542 1.52426855871966e-17 -50.6092137485582 117.063623289461 -0.432322290447288 0.665679138129568 USP39 essential 5.60688233608354e-13 1 2.03505095274662e-13 8.82354116802542 -0.432322290447288 7.12677343583603e-17 96.5734318855406 22.1812608336811 4.35382968577237 1.59874797638341e-05 -198.491304039374 43.3612388750062 -4.5776206858745 5.83287344418538e-06 TNIP2 other 7.79882817083536e-13 0.0714060367037174 0.141617095748042 4.35382968577237 -4.5776206858745 2.7015407508069e-19 172.409093707768 18.4906490910673 9.3241233911609 2.82122900125444e-19 -75.9690869124983 67.4399323030727 -1.12647039103029 0.260464964749503 C2orf68 other 3.15053682359101e-15 1 3.84872060351131e-15 9.3241233911609 -1.12647039103029 3.29277197659211e-05 33.0951445725248 11.67146616732 2.83556016854086 0.00474540696175509 -136.114349750594 42.5686996884235 -3.19752190569283 0.00146702091849271 TMEM150A other 0.19019050936796 1 1 2.83556016854086 -3.19752190569283 7.87730595889339e-09 230.869343847426 41.3684876578933 5.58080212544041 3.78703469283359e-08 -297.515777880947 150.881020638513 -1.97185687518477 0.0491340094403914 RNF181 other 6.13484588078617e-05 1 0.000395404292278755 5.58080212544041 -1.97185687518477 0.0418412131731258 36.3721037519151 17.8539704324433 2.03719973042083 0.0421153057778559 -78.8886249779226 65.1178090814951 -1.21147541802571 0.226241167981382 VAMP5 other 1 1 1 2.03719973042083 -1.21147541802571 7.7712294341439e-27 64.9692825335224 5.64003700918061 11.5193007470994 1.2896318486805e-27 23.3295717058399 17.3725529205291 1.34289829552175 0.179866993859825 LRRC28 other 1.02929933855236e-22 1 1.87435092887224e-23 11.5193007470994 1.34289829552175 0.394193206656033 92.5915037996435 110.081596930453 0.841117011212516 0.400653314100384 -383.347140121445 401.494582923556 -0.954800279819552 0.340104348713002 MAT2A essential 1 1 1 0.841117011212516 -0.954800279819552 1.15626823847217e-10 32.6794757414029 13.9441407141648 2.34359910813337 0.0194765886681844 -102.55778249631 23.3759190303121 -4.3873262207711 1.39150176989666e-05 PLA2G4F other 9.93928177790681e-07 0.166576676874329 1 2.34359910813337 -4.3873262207711 0.12103517707944 28.829338413888 21.9045885143865 1.31613238910895 0.18869217770101 -63.8560609666588 58.4164631893897 -1.09311754735362 0.27483322974586 ENHO other 1 1 1 1.31613238910895 -1.09311754735362 0.00610494210079178 -43.054412625593 22.1955974287794 -1.93977264021592 0.0529238535456916 -156.176604582075 50.351071250074 -3.1017533630299 0.00202356045711603 ZNF608 other 1 1 1 -1.93977264021592 -3.1017533630299 0.170490239538347 7.74606928865221 4.24521276922492 1.82465984857255 0.068601694249467 -2.39049705750126 15.2680423293226 -0.156568668460544 0.875642990848949 SLC35G2 other 1 1 1 1.82465984857255 -0.156568668460544 0.29933788157488 -42.0592286965919 28.3495023159109 -1.48359672166049 0.138491887950496 -50.6194809220533 56.4388819518019 -0.896890214183933 0.370172058339803 INPP5D other 1 1 1 -1.48359672166049 -0.896890214183933 5.60364651433912e-26 504.37520295869 61.6187036256228 8.18542379637075 2.01113796602136e-15 -457.506636891266 135.103055955427 -3.3863529855476 0.000760537249480147 LETM1 essential 7.34357875704142e-22 1 2.59115015542192e-11 8.18542379637075 -3.3863529855476 7.80427038648114e-34 232.615092624432 28.4249021057581 8.18349670155277 2.01198732381518e-15 -473.302551945944 73.6824919417496 -6.42354159683032 2.93607682809024e-10 TMEM129 other 1.10414817427935e-29 4.16012725772106e-06 2.59204326927109e-11 8.18349670155277 -6.42354159683032 0.00747491170616016 12.9312223418042 43.5591250316261 0.296865980030946 0.766681727530953 -274.993484089995 98.400107072598 -2.79464618760129 0.00537831752032418 PPIC other 1 1 1 0.296865980030946 -2.79464618760129 3.03401496019605e-22 63.1719702269824 18.1513597469024 3.48028859037753 0.000540985353299342 -320.243612617522 40.8904052750849 -7.83175442901884 2.52833529978954e-14 CEP120 other 3.75550371773067e-18 3.77278193434595e-10 1 3.48028859037753 -7.83175442901884 0.447593110338177 6.50472333143749 5.15287610041573 1.26234809544765 0.207371493725107 3.68668774740403 12.8211779352871 0.287546726674571 0.773804660179723 STXBP6 other 1 1 1 1.26234809544765 0.287546726674571 2.33207813060239e-14 165.536935940369 27.3259857680887 6.05785779679659 2.59063964327062e-09 -201.414022946844 57.2175266670057 -3.52014556866522 0.000467809502189047 MFF other 2.34816946970355e-10 1 2.83493696163104e-05 6.05785779679659 -3.52014556866522 0.161448906901388 60.1779454614837 37.1142401036313 1.62142469557381 0.105565929797244 243.071433860367 172.436482533701 1.4096288110775 0.159279819611404 LGALS9 other 1 1 1 1.62142469557381 1.4096288110775 3.30341690418722e-17 -9.55542586486324 28.1410410171072 -0.339554811033978 0.734332424460564 -384.100800339698 47.6666415143049 -8.05806300039889 5.59601321908612e-15 JMJD7-PLA2G4B other 3.65192738757897e-13 8.40073504449208e-11 1 -0.339554811033978 -8.05806300039889 3.06397565235851e-10 -0.156041907194107 13.2640920025025 -0.0117642358907544 0.990618323769781 -180.915396295007 29.6760503899174 -6.09634347960514 2.14625334653875e-09 CPLX1 other 2.58048029441634e-06 2.98457990369679e-05 1 -0.0117642358907544 -6.09634347960514 9.2445202142747e-07 176.982754227661 34.6062002053338 5.11419205742165 4.40446956808447e-07 326.4369146959 105.039614769684 3.10775049405563 0.00198591005029067 PXDC1 other 0.00619845080367118 1 0.00433708118369277 5.11419205742165 3.10775049405563 0.999212119746003 0.0262667660208516 1.93506571121187 0.013574095116595 0.989174739132331 0.276791556104781 7.04513458091593 0.0392883276998798 0.968674899962363 SIGLEC7 other 1 1 1 0.013574095116595 0.0392883276998798 3.59488497603747e-25 61.1089222635603 6.05054673741807 10.0997355967268 4.25999627618459e-22 -36.126405975719 18.0171078890684 -2.00511681442714 0.0454454569230805 E2F6 other 4.65429757847571e-21 1 5.9656987851689e-18 10.0997355967268 -2.00511681442714 6.93691631815404e-31 720.511719836334 73.2322845813596 9.8387169532566 3.98084565347349e-21 -733.312306632746 158.688473128783 -4.62108111682208 4.77570559603143e-06 FEM1B other 9.56739498599805e-27 0.0587220760088025 5.53058886637072e-17 9.8387169532566 -4.62108111682208 3.29552531293133e-12 51.6198481449044 10.429199641906 4.94955029314892 9.95653529549657e-07 -66.7993603919693 22.8815459216196 -2.91935521405719 0.00365392164510739 COMMD8 other 3.05396330749347e-08 1 0.00957719130073815 4.94955029314892 -2.91935521405719 1.0050029265471e-15 582.495663518739 80.085766059542 7.2733981602382 1.33567300498619e-12 -173.758104396653 179.73100817192 -0.966767538690076 0.334120273824765 ATP5I other 1.06299159540887e-11 1 1.61936995124525e-08 7.2733981602382 -0.966767538690076 5.64941964560574e-13 250.48573555502 33.925049814945 7.38350383923899 6.2731643120149e-13 -64.5786576848402 130.798210113939 -0.49372738073851 0.621710037779667 UQCRFS1 essential 5.38389692226227e-09 1 7.65765167567658e-09 7.38350383923899 -0.49372738073851 7.91188337043872e-09 -3.96262778397143 40.2533192670547 -0.0984422615606421 0.921619948363951 -509.828392495513 90.3377717427966 -5.64357945364272 2.77162140595145e-08 MFSD7 other 6.16019239222359e-05 0.000373642281736315 1 -0.0984422615606421 -5.64357945364272 0.318981806246802 4.4148749512971 3.15002372020015 1.40153704970088 0.161633385589124 -0.975022232861169 6.59418756667794 -0.147860858218258 0.882508287695 COL4A3 other 1 1 1 1.40153704970088 -0.147860858218258 9.44534927837147e-48 380.418113988027 23.8577904878684 15.9452365960489 3.69713506845123e-47 51.2129295030954 54.9094844976729 0.932679116761074 0.351404039683938 MAP2K1 other 1.42048607797429e-43 1 5.64626467653871e-43 15.9452365960489 0.932679116761074 0.389755721671935 15.2814351700649 53.8893470206785 0.283570613023035 0.776847148293145 269.60328584938 196.225458935339 1.37394651699207 0.17002308954641 KLK7 other 1 1 1 0.283570613023035 1.37394651699207 2.10474353114932e-08 741.941610273261 139.264869241907 5.32755758370396 1.46180380970798e-07 -377.187061141421 372.807598131737 -1.01174724719032 0.312110362322243 HNRNPH1 essential 0.000159771081449545 1 0.00147759129085283 5.32755758370396 -1.01174724719032 2.70736828733759e-06 -88.5797017107427 121.155004197589 -0.73112705742043 0.465015762359342 -1321.42772784746 260.332806319045 -5.07591704069757 5.29996238063636e-07 IRS1 other 0.017370474931558 0.00681204164783191 1 -0.73112705742043 -5.07591704069757 1.8744124575909e-42 177.081616260052 15.1334301218045 11.7013535487179 2.61481732427044e-28 -181.136481789612 35.598589482849 -5.08830502615509 5.01497350604228e-07 UPF3A other 2.77413043723453e-38 0.006452264912874 3.81554143957543e-24 11.7013535487179 -5.08830502615509 0.0172773201389902 1.38853467686164 28.8458143711139 0.048136435289971 0.961625207975074 -170.354608348011 63.6281734083893 -2.67734557229251 0.00764530894887196 ROR2 other 1 1 1 0.048136435289971 -2.67734557229251 0.187303438677112 18.3237738100506 10.6536959090065 1.71994526280404 0.0860305951897126 -43.1517201805045 97.4812438440537 -0.44266690164045 0.658188661834462 C8orf46 other 1 1 1 1.71994526280404 -0.44266690164045 4.54039903582688e-09 24.91133197006 4.38186347628693 5.68509998197598 2.13290845292008e-08 -23.573799145764 14.2995092804075 -1.64857399533729 0.0998112323695473 HSPBAP1 other 3.58827735801398e-05 1 0.00022525646171289 5.68509998197598 -1.64857399533729 6.20203375736672e-10 80.0676860015272 20.0618402500075 3.99104394231718 7.48205151598299e-05 -97.3191164313231 35.6018988562692 -2.73353724261216 0.00647018253124864 CHST14 other 5.13776476460259e-06 1 0.625574327251338 3.99104394231718 -2.73353724261216 0.00340094059427992 199.091504363804 80.9758062330978 2.45865417864068 0.0142586250324763 -333.477497696452 244.783408442703 -1.36233701384426 0.173659493734589 PARM1 other 1 1 1 2.45865417864068 -1.36233701384426 5.1640055973026e-30 286.471435470634 29.2646890083455 9.78897931869156 6.24964379373783e-21 -304.22365660557 65.4866913766042 -4.64557989127935 4.27057109567127e-06 CSNK1G1 other 7.06539245822941e-26 0.0526561416096268 8.67013083505249e-17 9.78897931869156 -4.64557989127935 2.44450857255189e-06 86.7157663775472 20.4571534709251 4.23889699516565 2.66327111809032e-05 -409.660792567326 171.030827041599 -2.3952453464292 0.0169661170019076 FAM110B other 0.0157621912758146 1 0.23175785269622 4.23889699516565 -2.3952453464292 0.464599868602885 2.17925607568345 3.02921607233853 0.719412555473827 0.472195695411195 -8.90521301018093 11.0933793268549 -0.802750248395742 0.422469670521627 ARMC4 other 1 1 1 0.719412555473827 -0.802750248395742 0.0237887361915065 20.0506710119392 78.6260254859691 0.255013157386638 0.798809670988202 -368.408613002092 152.666237555849 -2.41316363657236 0.0161454753004986 AFAP1L2 other 1 1 1 0.255013157386638 -2.41316363657236 2.84429974203814e-10 59.1875875982255 9.53718295411475 6.20598219442665 1.08085802651147e-09 -10.8928512008306 25.6971930705915 -0.423892647376211 0.671812284222995 ZNF354A other 2.39916683240917e-06 1 1.2015898680728e-05 6.20598219442665 -0.423892647376211 4.48508072110197e-68 464.713534273531 22.3460865893707 20.7961932132931 7.5508875672588e-68 -140.911597333009 179.158810727591 -0.786517820478634 0.431977254206146 UBE2V2 other 6.93258927060731e-64 1 1.17076511730348e-63 20.7961932132931 -0.786517820478634 2.94373039799795e-21 69.537195773121 12.702173330293 5.4744329151362 6.72142197925506e-08 -178.804989403379 28.3270150948621 -6.31217192508963 5.72844453158894e-10 ZBTB43 other 3.57368870316951e-17 8.06965981164934e-06 0.000693717962478915 5.4744329151362 -6.31217192508963 0.33790974613195 -4.27990042391047 5.73548520570906 -0.746214185968134 0.455861568163391 -26.9095338955905 18.9230871168113 -1.42204777315029 0.155587576787664 CPT1C other 1 1 1 -0.746214185968134 -1.42204777315029 0.369551021793108 18.3924612659648 13.4080992351635 1.37174262685418 0.170712164233096 3.91107824289105 30.2772948965328 0.129175286506158 0.897266960020559 PCSK9 other 1 1 1 1.37174262685418 0.129175286506158 4.30537573946914e-24 419.606310869493 39.6101019373262 10.593416586845 5.99048316141423e-24 -42.4900429749864 234.45335915617 -0.181230258879267 0.856254972041168 XPO6 other 5.48763191752736e-20 1 8.52685373195702e-20 10.593416586845 -0.181230258879267 0.00972466172274617 -3.79347507515482 20.2109218760346 -0.187694311937992 0.851187056603184 -118.233824731303 42.566652917502 -2.77761620018493 0.00566701938288462 MN1 other 1 1 1 -0.187694311937992 -2.77761620018493 3.04829586812359e-26 343.843805152852 35.0835007832298 9.80072676547753 5.4816722570876e-21 -708.568701495036 200.705558907094 -3.530389020381 0.000450257906668252 NSMCE1 essential 4.00607042988802e-22 1 7.6091092600633e-17 9.80072676547753 -3.530389020381 0.000846049434292722 0.422508476957247 15.5204207175861 0.0272227463833185 0.978292168042314 -264.022003637695 71.6949743376893 -3.68257337528471 0.000254209227534725 CCDC126 other 1 1 1 0.0272227463833185 -3.68257337528471 0.0278619864294188 11.5066671393306 37.0103204808353 0.310904282638918 0.755993808560961 -179.912758723248 74.856599911817 -2.40343214806964 0.016579368499467 RAB3B other 1 1 1 0.310904282638918 -2.40343214806964 1.34879411069022e-34 454.303033434966 37.9400224138602 11.9742426211377 2.04363586116291e-29 -698.677361635054 230.184730558512 -3.0352897863373 0.00252086340597193 CD2BP2 essential 1.91865962245683e-30 1 2.99617453605094e-25 11.9742426211377 -3.0352897863373 0.570500044347408 -28.7628313935486 27.8369025876444 -1.03326263771585 0.301942673457294 -32.0157763517407 57.6722847124385 -0.555132790583476 0.579033289197436 RSPO1 other 1 1 1 -1.03326263771585 -0.555132790583476 2.15014627173663e-09 52.8845223758979 16.0760541695861 3.28964569402539 0.0010689169396372 -185.498858950888 45.7837396018962 -4.0516318798739 5.83704503511975e-05 RGS14 other 1.73172780725668e-05 0.669800917779991 1 3.28964569402539 -4.0516318798739 2.43708249661915e-38 321.908934747368 25.2358566857755 12.7560137448718 1.0722951720657e-32 -484.325533289024 153.107681599744 -3.16330002667766 0.00164916729814291 TBC1D10B other 3.54278682533526e-34 1 1.59117880582829e-28 12.7560137448718 -3.16330002667766 4.39097277143427e-13 498.866927645638 113.905314066262 4.37966333471882 1.42903927886609e-05 -1454.18781320632 324.397861803803 -4.48272934081734 9.01096271971502e-06 LMAN2 other 4.20216094226259e-09 0.109131769498469 0.127155915033505 4.37966333471882 -4.48272934081734 4.61299338213269e-14 101.30443842476 19.2006895411277 5.27608335147374 1.9163558794883e-07 -213.290066871783 54.6828098702849 -3.90049573856457 0.000108149962317948 RAB24 other 4.5926962112513e-10 1 0.00192670420123753 5.27608335147374 -3.90049573856457 1.92509625307698e-10 272.908620463165 42.909429672953 6.36010831519363 4.31156545156107e-10 -16.8954746966535 122.20437080775 -0.138255895308632 0.890089912184533 PRELID1 essential 1.64075953649751e-06 1 4.87034433408338e-06 6.36010831519363 -0.138255895308632 1.15752060430265e-09 135.530051891028 20.8538599809919 6.49903912343146 1.88150413470605e-10 86.7681967867476 216.26544562251 0.401211559881836 0.688427616675545 THBS3 other 9.43726548687953e-06 1 2.14848957142084e-06 6.49903912343146 0.401211559881836 1.04746959801299e-22 543.509844430343 51.5437523321807 10.5446309171987 1.03995737236872e-23 56.0767728906873 537.205646803304 0.104386045128859 0.916902862246522 SLC50A1 other 1.30682307048101e-18 1 1.47725944744977e-19 10.5446309171987 0.104386045128859 1.20388167711546e-10 426.895465036045 65.2651905640774 6.54093646776253 1.45081705202663e-10 1271.52880852388 680.884089199499 1.867467354126 0.0623922854608137 EFNA1 other 1.03317125530049e-06 1 1.66278142332772e-06 6.54093646776253 1.867467354126 0.000734648054455487 465.346021266909 135.405876439498 3.43667522786453 0.000634089753050492 1094.51777984595 398.08544150754 2.74945442792641 0.00616869116608016 CXCL10 other 1 1 1 3.43667522786453 2.74945442792641 9.64099281740308e-05 1.04406605131166 4.22694494218962 0.247002519689982 0.804998779731087 41.4716528405864 9.99738521542302 4.14824996206087 3.88264158692719e-05 SH3TC2 other 0.524855648979423 0.450929993905724 1 0.247002519689982 4.14824996206087 5.48223051481402e-05 169.165993841707 41.2646208328222 4.09954073071601 4.7742326159454e-05 372.87013078949 121.315597482323 3.07355474916423 0.00222167640055532 CXCL11 other 0.308265821847993 1 0.406143968638475 4.09954073071601 3.07355474916423 2.32336870237104e-11 205.300182474044 28.7786039424689 7.13377837522828 3.16958401517606e-12 -34.9967264494434 108.462740597415 -0.322661277565739 0.747077135405103 NMD3 essential 2.0682628188507e-07 1 3.80920606943858e-08 7.13377837522828 -0.322661277565739 2.27120358116372e-05 17.7069328082854 6.25894582303313 2.82905992621365 0.00483950322417588 -37.1749032580022 14.800583197504 -2.51171881282836 0.0123008725784664 ADRB2 other 0.133251514106875 1 1 2.82905992621365 -2.51171881282836 6.11596019588518e-05 87.7648164100191 23.249742124361 3.77487268205266 0.000177901798610956 -191.964819107888 87.6251938430557 -2.19074915202714 0.0288982285012234 B3GALNT1 other 0.341759855746064 1 1 3.77487268205266 -2.19074915202714 0.000164193070260911 56.8565368825379 14.5865697655405 3.89786891616263 0.000109344382473437 117.230746603345 41.3071014066585 2.83802887666303 0.00471132146528115 GPRIN1 other 0.86726779711813 1 0.900560334051229 3.89786891616263 2.83802887666303 0.0636712299376036 11.67520598793 8.16485366128385 1.4299345061494 0.153313057133122 60.2498753711927 31.3470412506419 1.92202750139805 0.0551271796533767 KCNAB1 other 1 1 1 1.4299345061494 1.92202750139805 1.35526542507711e-18 94.0121123948598 11.3818216716954 8.25984759791586 1.13888080408701e-15 -34.4586812145636 28.8183954269385 -1.19571824537992 0.232333279395119 MRPL1 other 1.55150785862827e-14 1 1.4725728796845e-11 8.25984759791586 -1.19571824537992 0.0638821597820624 13.2780078626177 7.75616000620546 1.71193062701058 0.0874944399462627 -141.861360903908 80.2344706553996 -1.76808496080433 0.0776219522655636 SHE other 1 1 1 1.71193062701058 -1.76808496080433 0.0297506844682523 60.1686798292531 35.1138379474834 1.71353185371653 0.0871833917662764 -58.2050177312947 67.0465485739764 -0.868128471476405 0.38570610717043 PGM2 other 1 1 1 1.71353185371653 -0.868128471476405 0.194622405005242 4.98670853415435 3.80754594115236 1.30969096925594 0.190849190631021 14.5034006052614 8.8806236859874 1.63315112970569 0.103011600969533 STK32A other 1 1 1 1.30969096925594 1.63315112970569 0.441816070304329 -2.41590773914351 2.05772897930391 -1.17406508021322 0.240879863506059 4.91915288844646 9.63741125935123 0.510422639033213 0.609961310151796 P2RY12 other 1 1 1 -1.17406508021322 0.510422639033213 2.09325623022689e-11 5.88845366532526 0.871642967751421 6.75557984539899 3.64838757949942e-11 2.13345574892809 1.98213267996882 1.07634356190609 0.282248118765564 C22orf15 other 1.86781253423145e-07 1 4.25584411148607e-07 6.75557984539899 1.07634356190609 3.07015393990064e-17 35.7441128020802 3.95636444570243 9.03458548691261 2.87625819347731e-18 22.5149261407539 9.70791707038757 2.31923346455359 0.0207525353219813 KIAA1024 other 3.39681831910606e-13 1 3.87863417390416e-14 9.03458548691261 2.31923346455359 0.155549098371892 -267.143476196256 216.907656942411 -1.2316000272281 0.218627739734417 -2010.007139171 1139.45710269646 -1.76400422132122 0.0782894135114005 GP2 other 1 1 1 -1.2316000272281 -1.76400422132122 5.05419880430191e-09 164.487437754989 27.3854800247276 6.00637409336866 3.47673946930252e-09 -172.600126636041 105.309003214573 -1.6389873739889 0.101795112327351 SLC33A1 other 3.98018155838775e-05 1 3.78651695601737e-05 6.00637409336866 -1.6389873739889 2.62075071410559e-22 126.551643455724 13.8747291458036 9.12101721956855 1.4509135488686e-18 -73.1905409802937 30.1381817996157 -2.42849888778715 0.0154857372934653 SNUPN essential 3.24763428491965e-18 1 1.96381148839365e-14 9.12101721956855 -2.42849888778715 1.93080626890935e-20 31.4811840401645 4.94689646107108 6.36382513519362 4.22130347371456e-10 -71.9103466117406 12.7566136815952 -5.63710310640594 2.79674661701871e-08 CRADD other 2.30596192695844e-16 0.000376973476507952 4.77007292529746e-06 6.36382513519362 -5.63710310640594 9.2947920867435e-25 471.84531480112 64.2360202852951 7.34549420567286 7.55730719988908e-13 -857.091200152559 139.843115603809 -6.12894811769493 1.70171566874078e-09 SIN3A essential 1.19698332493083e-20 2.37168112752402e-05 9.20857882306484e-09 7.34549420567286 -6.12894811769493 0.00170617582293237 16.4521564849946 7.80668093493509 2.10744574065667 0.0355684040096566 -72.2516623090437 26.9054883662977 -2.68538750627353 0.00748151173532093 ARL13B other 1 1 1 2.10744574065667 -2.68538750627353 0.0770799523150819 -1.28428762809472 0.785522846594605 -1.63494624460939 0.102635618201859 2.09940300757985 2.20300221162797 0.952973626852799 0.341024345997259 RNASE2 other 1 1 1 -1.63494624460939 0.952973626852799 4.31901754320271e-77 825.763950178119 37.5548316847489 21.9882213055814 5.27441829205074e-77 -276.901924448867 295.922235509404 -0.935725306252181 0.349832899936593 PTK2 other 6.70786614634812e-73 1 8.20488509511414e-73 21.9882213055814 -0.935725306252181 4.64414989736556e-15 40.6699956672443 5.2653690919269 7.72405408950369 5.43896107094475e-14 -20.254237976603 18.8099022221952 -1.07678592569734 0.282052319409002 RSPH10B2 other 4.80297982385546e-11 1 6.81719380632215e-10 7.72405408950369 -1.07678592569734 0.169335498050848 33.5367143746112 27.0956095859087 1.23771765563275 0.21635568402669 -26.3792263015972 43.517113234421 -0.606180519362482 0.544648205195761 PTAFR other 1 1 1 1.23771765563275 -0.606180519362482 5.70480587132231e-23 286.903278977314 30.2278000568625 9.49137146724575 7.18722541203545e-20 -132.208951510068 65.6597274038816 -2.01354706663391 0.0445508712653385 PTPN9 other 7.14583983441832e-19 1 9.86877921326588e-16 9.49137146724575 -2.01354706663391 0.25626174181691 -17.91857793464 10.8806685692905 -1.64682692249382 0.100167964165166 -20.1812805381548 30.3664019214287 -0.664592419950596 0.506591286210284 RNASE6 other 1 1 1 -1.64682692249382 -0.664592419950596 0.269544827725326 31.8508184936593 24.6666001768803 1.2912528790049 0.197170523306833 -251.411435938709 244.514737674365 -1.02820565471816 0.304315140194652 NPR1 other 1 1 1 1.2912528790049 -1.02820565471816 9.92409427229528e-09 53.6103009004963 17.8670444337423 3.00051310105057 0.00282018809427422 337.861061085551 55.5125017132854 6.08621572903629 2.19840640989406e-09 CXCL8 other 7.67529451019317e-05 3.05622459103472e-05 1 3.00051310105057 6.08621572903629 0.296708194759272 3.61497603602141 3.60580425977993 1.00254361456715 0.316527657102174 -7.60319380456688 8.97405425349731 -0.84724179170232 0.397233627804662 SCN9A other 1 1 1 1.00254361456715 -0.84724179170232 0.650918231123894 15.9163641951383 34.6107802752482 0.459867245654696 0.645797293697846 -65.1189811900053 107.004404606669 -0.608563558008403 0.543070613258059 RASSF6 other 1 1 1 0.459867245654696 -0.608563558008403 0.160492818089656 24.7616393439067 16.1096839912041 1.53706549162768 0.124857608934126 171.996545548843 131.429991041609 1.30865523299314 0.191202732729895 COL22A1 other 1 1 1 1.53706549162768 1.30865523299314 0.00311569887767258 321.288360846365 94.9187260447649 3.38487856121079 0.000764546819597526 555.460223781587 986.325667778374 0.563161075421184 0.573562025677347 SDC2 other 1 1 1 3.38487856121079 0.563161075421184 0.255714688657278 -496.5914782468 656.114030483933 -0.756867640645524 0.4494556324825 945.414169786148 1077.80825827579 0.877163598002638 0.380783566113614 CD52 other 1 1 1 -0.756867640645524 0.877163598002638 0.815943522818305 -2.92845253044419 6.33626103848272 -0.462173593016212 0.644141620792726 -30.6791909320948 73.4630121010725 -0.41761411701831 0.676394046839197 SPRR1B other 1 1 1 -0.462173593016212 -0.41761411701831 1.26229833745431e-250 507.531958542107 7.07809021059022 71.7046467962134 9.60988862588704e-250 12.643929512522 87.6918438100603 0.144185923834702 0.885417636393202 TM2D2 other 1.97953625279584e-246 1 1.50702273431161e-245 71.7046467962134 0.144185923834702 0.000268851898720156 0.660407530515552 0.184203963249662 3.5851971850381 0.00037333714412476 5.73611266247399 2.27478434968002 2.52160722983735 0.0120231975438934 HTRA4 other 1 1 1 3.5851971850381 2.52160722983735 1.97053344212388e-70 138.835340621484 6.63354533991014 20.9292819310653 1.5204038369225e-68 -166.396910140941 81.4759159468297 -2.04228339389924 0.0417019423053773 PLEKHA2 other 3.05018871506356e-66 1 2.35814635106681e-64 20.9292819310653 -2.04228339389924 0.00830124169766159 658.730616910697 291.304070160986 2.2613162134901 0.0241330228413048 -298.093972833716 463.231830686675 -0.643509260561465 0.52016438752481 CLIC4 other 1 1 1 2.2613162134901 -0.643509260561465 0.341851069543643 -9.45240828337177 9.59669809022098 -0.984964640390611 0.325080917724813 -31.6775213854425 23.8986373295512 -1.32549487858342 0.185565491104984 SLC38A11 other 1 1 1 -0.984964640390611 -1.32549487858342 0.547072695924753 6.9863283411062 11.0328386517177 0.633230355455119 0.526852302800234 28.7190955538818 27.1479790027947 1.05787232084294 0.290588404862121 GPR183 other 1 1 1 0.633230355455119 1.05787232084294 0.852901423521349 -16.4385378277778 32.9007744537419 -0.499639844371753 0.617529975482925 -40.2667565619695 96.0320889446295 -0.419305223956823 0.675157995702413 CCDC8 other 1 1 1 -0.499639844371753 -0.419305223956823 1.02981905354296e-17 48.0929220561181 10.8218582105885 4.44405398040259 1.0732325820589e-05 -163.611282679179 27.036821737454 -6.05142439699297 2.6984659082294e-09 METTL15 other 1.15370628568418e-13 3.74385160107746e-05 0.0964621444754541 4.44405398040259 -6.05142439699297 0.214037634583743 45.0190395827744 28.6370123979362 1.57205783051653 0.116529426479346 -15.5466292341583 73.7098047722315 -0.210916706158678 0.833032729051814 MUC15 other 1 1 1 1.57205783051653 -0.210916706158678 0.201322278685307 -6.29638494153501 51.6569247372605 -0.121888497496898 0.903033438370357 -208.584690259932 120.695019344318 -1.72819633646093 0.0845343804747456 ZEB2 other 1 1 1 -0.121888497496898 -1.72819633646093 2.06118342006445e-09 533.379591538492 122.023448093294 4.37112374607455 1.48068757036556e-05 -1639.97284301307 409.156849539885 -4.00817643614495 6.97079807010409e-05 PCBP1 essential 1.66193219159796e-05 0.79494981191467 0.131529476875573 4.37112374607455 -4.00817643614495 2.68291830584442e-11 313.033172037552 105.290572420186 2.97304084157053 0.00307879602715519 -1201.32783337193 248.138518703793 -4.84135973587385 1.68123731463614e-06 HINT1 other 2.38167433095997e-07 0.0211264280957177 1 2.97304084157053 -4.84135973587385 1.00921960709593e-20 9.83812373973911 9.85186848844145 0.998604858690666 0.318431757208924 -197.12413867183 22.2351998988377 -8.86540888180341 1.09844650110311e-17 DTWD2 other 1.21237551400434e-16 1.67754749648466e-13 1 0.998604858690666 -8.86540888180341 0.0994198936205102 21.2719404497558 14.6195145464382 1.45503740101537 0.146275323351762 67.0261289363486 33.9575921303171 1.9738186582584 0.0489426989717252 CLIC3 other 1 1 1 1.45503740101537 1.9738186582584 3.32684487186949e-20 246.381647565321 28.8218753653752 8.54842526525212 1.31724921557561e-16 -485.580004287913 173.523263204043 -2.79835680428006 0.00532190043843114 INO80E other 3.95395513021689e-16 1 1.73244616832504e-12 8.54842526525212 -2.79835680428006 0.0078313645038065 56.268019316532 20.2453284655357 2.77930878781833 0.00564089435593821 93.7132515077068 42.892068950853 2.18486199896504 0.0293362067715193 BNC1 other 1 1 1 2.77930878781833 2.18486199896504 2.35677407997433e-08 19.5671976911792 5.17976649178325 3.77762158240512 0.0001758321474126 -20.0567751034851 8.73594721924461 -2.2958901422048 0.0220622714226561 DFFB other 0.000178289959150058 1 1 3.77762158240512 -2.2958901422048 0.0180110921312709 17.6186583459908 17.2008101635111 1.02429235475002 0.306150797333498 -143.063980939615 58.0669891487941 -2.46377473736445 0.0140554083180431 NFU1 other 1 1 1 1.02429235475002 -2.46377473736445 0.188564988519364 -292.010962120634 315.497273289191 -0.925557799838641 0.355084729667061 -1812.88416317681 1065.06475976466 -1.70213514864334 0.0892992556808215 ANTXR1 other 1 1 1 -0.925557799838641 -1.70213514864334 2.00315051527296e-07 100.30207910468 18.5959920473504 5.39374714988497 1.03002850189887e-07 133.981280363392 49.0222332047175 2.73307174326155 0.00647845158062505 CKAP2L other 0.00141662804440104 1 0.00105052606908666 5.39374714988497 2.73307174326155 8.2851016357106e-26 72.8899125246057 9.51310552349146 7.66205234921582 8.74445535210962e-14 -115.734071603861 20.1434518103602 -5.74549350793671 1.54549687395694e-08 C15orf40 other 1.08311133683645e-21 0.000210094845045706 1.09017124874751e-09 7.66205234921582 -5.74549350793671 5.23027785877246e-24 84.3963158812876 9.0214282649045 9.35509471483683 2.3181138673835e-19 -48.9648033763808 19.0356857736354 -2.57226369244851 0.0103737462112925 FAM103A1 other 6.65657463085971e-20 1 3.1667753542326e-15 9.35509471483683 -2.57226369244851 0.0693609817582684 3.61687740467443 12.094487401328 0.299051731971484 0.765014573709768 -69.7218061287722 31.9734874807893 -2.18061311487098 0.0296389680453465 RGPD8 other 1 1 1 0.299051731971484 -2.18061311487098 2.82800345925682e-20 39.3798361384732 4.79906049580622 8.20573863840356 1.78096411225554e-15 -8.66289221945648 9.93946049889723 -0.871565636828841 0.383843769756463 HIC2 other 3.36730371893709e-16 1 2.2970875119872e-11 8.20573863840356 -0.871565636828841 1.5368369703899e-05 51.3725434143181 44.8485954383474 1.14546604887413 0.252517968058059 -233.422120134271 70.5932903000551 -3.30657657607566 0.00100652378744237 LUZP1 other 0.0919335875687241 1 1 1.14546604887413 -3.30657657607566 9.02626769331758e-13 63.7093926363142 15.2499948476071 4.17766650237989 3.45109552932397e-05 -238.767416169711 43.4710282668705 -5.49256425920979 6.19207779488618e-08 HEXDC other 8.5406544914171e-09 0.00082534204928038 0.2976224784489 4.17766650237989 -5.49256425920979 2.63468688982084e-11 254.487922718775 36.6057172940085 6.95213593753097 1.04210332603186e-11 322.805752977139 105.224567366703 3.06777933191375 0.00226471010581347 BUB1 other 2.34039236422785e-07 1 1.2362471756716e-07 6.95213593753097 3.06777933191375 3.30073095883552e-18 196.863324800359 22.9943525427479 8.56137716573574 1.18374268598572e-16 -190.767837740067 138.032535834124 -1.3820497941827 0.167532087015061 SPNS1 other 3.74335898041536e-14 1 1.558160497563e-12 8.56137716573574 -1.3820497941827 2.32060432251624e-10 144.347903211072 25.1242943422736 5.74535154080707 1.55113639186084e-08 -179.29117844459 71.6241087610469 -2.50322386618092 0.0126076425589731 LRRC45 other 1.96985938107618e-06 1 0.000164792730271295 5.74535154080707 -2.50322386618092 1.75643347648514e-14 47.4265709655117 8.28029752112942 5.72764092648724 1.69107580789212e-08 142.453334297635 19.9557402470109 7.13846404765527 3.0535666394275e-12 CHRNA5 other 1.77768632155061e-10 4.46431442684301e-08 0.000179372410943117 5.72764092648724 7.13846404765527 1.94231224141818e-16 259.454823719482 33.0368435323861 7.85349918387748 2.27525975392318e-14 -230.025170782382 94.1811316986498 -2.44237000165161 0.0149180754583265 CENPX other 2.0984741456282e-12 1 2.87319801725419e-10 7.85349918387748 -2.44237000165161 9.6702257562154e-06 336.198183729423 90.5523528959876 3.71274928786881 0.00022733854061884 -365.443237634951 209.252396837831 -1.74642318634069 0.0813324898611662 AGPAT2 other 0.058901345081108 1 1 3.71274928786881 -1.74642318634069 6.91681957470026e-13 139.871830037608 23.3996252504339 5.97752436377222 4.17327951922226e-09 -241.934583460433 66.7074378715924 -3.62680071637801 0.000314795921732582 ASPSCR1 other 6.57236195988019e-09 1 4.52967759016384e-05 5.97752436377222 -3.62680071637801 9.50231520750845e-07 3109.30249230569 1300.34072618749 2.39114443598329 0.0171444475059961 -15756.2519128512 3701.3797136118 -4.25685909902938 2.45304542257874e-05 FASN other 0.00635894933686466 0.288772507145969 1 2.39114443598329 -4.25685909902938 8.72666324335178e-17 768.804359997949 114.036871836472 6.74171737278455 4.03743657021365e-11 -1628.41661717413 366.970191562649 -4.43746291828208 1.10424224131527e-05 CNBP other 9.52166226482113e-13 0.132983893121598 4.7015948860138e-07 6.74171737278455 -4.43746291828208 0.000518850312490981 -83.0026475190591 94.1934833913869 -0.88119309882799 0.378606805578601 -709.275737367854 201.026452683181 -3.52827067234617 0.000454065542159585 MT1E other 1 1 1 -0.88119309882799 -3.52827067234617 1.22460459970574e-14 503.908634106389 62.1752551332341 8.10464923749124 3.69074336697143e-15 -10.4862318246976 176.979943336489 -0.0592509615892479 0.952774595115093 DUS1L other 1.24713732434033e-10 1 4.73153299645737e-11 8.10464923749124 -0.0592509615892479 2.44320736291589e-31 595.29256087059 49.5313622648005 12.0184976477749 1.3981065905931e-29 -261.056088147955 141.330911326626 -1.84712661722414 0.0652880619261113 GPS1 essential 3.38652972573772e-27 1 2.05116217905914e-25 12.0184976477749 -1.84712661722414 7.88575689506489e-13 111.325259994464 23.2083995529124 4.79676591833297 2.10090105806176e-06 -330.545711574201 66.2219674417583 -4.99148129153538 8.15045708679808e-07 RFNG other 7.47569753652151e-09 0.0103950929685023 0.0198262032849288 4.79676591833297 -4.99148129153538 8.37362026131546e-10 339.840502474036 95.2619099948298 3.5674332216568 0.000393302889751245 -1302.63797905395 271.816722550595 -4.79233936319529 2.14582099295499e-06 DCXR other 6.87976640669678e-06 0.0268356373378951 1 3.5674332216568 -4.79233936319529 2.37543685509924e-16 152.286850817146 25.3122696651466 6.01632539601281 3.34093375664417e-09 -319.276215392406 72.80429842496 -4.38540336627908 1.39840680785274e-05 ZNF32 other 2.56072092979698e-12 0.167375310831894 3.64128370136648e-05 6.01632539601281 -4.38540336627908 0.00124154359414434 -45.2105437988183 24.1081613925821 -1.87532110236865 0.061283977336086 -170.592401101454 46.3668964768363 -3.67918523912157 0.000257257495048691 LDB2 other 1 1 1 -1.87532110236865 -3.67918523912157 2.56340326017589e-08 126.203074376377 22.2966692750195 5.66017609265844 2.48384765627695e-08 -60.0981629212609 63.6204708309887 -0.944635620206505 0.345276994007998 RAC3 other 0.000193562580175881 1 0.000261673350588777 5.66017609265844 -0.944635620206505 7.10856729886231e-13 17.3900623274503 2.26538587896894 7.67642391033406 7.69343855719614e-14 9.37361415372656 4.82356610828157 1.94329546715096 0.0524987492347102 NRG4 other 6.75029550699965e-09 1 9.6060273825151e-10 7.67642391033406 1.94329546715096 1.27056253998205e-07 210.600575631596 38.5028298736442 5.46974277793944 6.88695171600345e-08 -106.526195806112 139.018375066143 -0.766274211991242 0.443846143049257 LIMS1 other 0.000913026241231099 1 0.000710389069505756 5.46974277793944 -0.766274211991242 0.00189710145673526 3.15921941254971 1.20638951913486 2.61873910742799 0.00907297995317686 -4.17810579391796 2.56870127597577 -1.6265440567163 0.104416258875322 TMEM266 other 1 1 1 2.61873910742799 -1.6265440567163 0.716097899253677 -2.24106900865214 3.41127237831649 -0.656959855477193 0.511489229677733 7.1302069217137 14.5638381642965 0.489582954800578 0.624629715468894 NLGN1 other 1 1 1 -0.656959855477193 0.489582954800578 3.36278656487337e-24 62.578156489708 37.5833927900881 1.66504809289628 0.0964789300913454 -621.914122052817 71.8452054918091 -8.65630653841919 5.53254297768228e-17 TAPT1 other 4.29360588603031e-20 8.41721088624583e-13 1 1.66504809289628 -8.65630653841919 4.81406170268292e-20 973.045311364238 99.9959142703784 9.73085068989144 9.79004170151308e-21 79.6205621157285 351.692803182988 0.226392355473653 0.820981468396502 UGP2 other 5.70707014853061e-16 1 1.35533337315747e-16 9.73085068989144 0.226392355473653 1.03531298241425e-07 307.283601417622 58.7286685730147 5.23225894412351 2.39562482575234e-07 -118.557538363918 131.628800667956 -0.90069603128109 0.368149251775599 LINGO1 other 0.000748324223689017 1 0.00239466657582204 5.23225894412351 -0.90069603128109 7.45514364373748e-20 883.402156745267 150.229087392999 5.88036692544293 7.29748578841702e-09 -2481.39886419339 427.910004969697 -5.79888022101543 1.155004757919e-08 HNRNPF other 8.80377912888959e-16 0.000157519548884994 7.85647319980977e-05 5.88036692544293 -5.79888022101543 1.53963615601795e-18 56.1044017586268 19.202548051752 2.92171651425749 0.00362622658905206 -418.010188427594 52.2870334672164 -7.99452867582712 7.89494796972904e-15 BTD other 1.76041998079092e-14 1.18408429649996e-10 1 2.92171651425749 -7.99452867582712 1.33186141290332e-05 83.8560647104139 22.2517560506188 3.76851447228058 0.000183025160677663 -116.40095053791 64.1263300967303 -1.81518185061155 0.0700718952552315 CSGALNACT2 other 0.0801514198285216 1 1 3.76851447228058 -1.81518185061155 0.0158395975486322 -70.0854898803555 52.88606216134 -1.32521664529579 0.185658701092847 -279.645823555464 97.0143434047506 -2.88252039586314 0.00410187859678804 PCDH7 other 1 1 1 -1.32521664529579 -2.88252039586314 0.023509600034943 238.689645402574 86.9081512700411 2.74645866831199 0.00623026003204208 219.925217657375 172.546303690994 1.27458666429175 0.203017283406731 ROBO1 other 1 1 1 2.74645866831199 1.27458666429175 2.6640696987519e-05 42.5316317554248 9.25022364576196 4.59790307609599 5.31852995267128e-06 30.1910075140308 17.0347911746337 1.77231450650171 0.0769050933803358 AVEN other 0.155395185528198 1 0.0488879273249544 4.59790307609599 1.77231450650171 4.71864025062708e-05 16.8758562384049 3.85144494430687 4.38169478791342 1.41341849488581e-05 -12.8568061280631 15.4704221841097 -0.831057224880965 0.40630590542527 P2RY1 other 0.2678772070281 1 0.125808380229786 4.38169478791342 -0.831057224880965 0.00016892617075847 111.618786034513 30.2789839091533 3.68634516829907 0.000250345609375754 -219.323727765012 148.179837198089 -1.48011856344407 0.139421553178241 CTNND2 other 0.890578772238652 1 1 3.68634516829907 -1.48011856344407 1.94375787991676e-07 57.1351429431003 47.4716279980738 1.20356400975797 0.229286464647181 -689.813915976065 142.25865488648 -4.84901193903825 1.62571868245108e-06 TRIM56 other 0.00137695808213303 0.0204434124318223 1 1.20356400975797 -4.84901193903825 0.00216084787882086 8.1899717484449 2.6209873721066 3.12476581749506 0.00187452553234644 19.3214864491982 8.16550819632698 2.36623195821289 0.0183202767610365 WNT10B other 1 1 1 3.12476581749506 2.36623195821289 0.274826230033592 -0.321802105701747 2.81485827412742 -0.1143226672048 0.909024429023582 -8.66442565943394 5.75044060333315 -1.5067411798692 0.132460678880837 CALML6 other 1 1 1 -0.1143226672048 -1.5067411798692 0.725760454877071 -1.24315531519353 6.80072906038758 -0.182797359541137 0.855025501232511 -18.3777014323137 22.9907352418372 -0.799352488687316 0.424436861767557 MUC3A other 1 1 1 -0.182797359541137 -0.799352488687316 0.391276454721845 38.9896877027992 31.4138276429192 1.24116322741675 0.215113806333602 160.317036785236 185.076302440366 0.866221308029929 0.386774539952013 ITGAM other 1 1 1 1.24116322741675 0.866221308029929 0.258624765335131 18.2109652836422 19.3677026197461 0.940274933025633 0.347519080436812 -123.808650462445 114.165434816725 -1.08446703383735 0.278667165135774 PYDC1 other 1 1 1 0.940274933025633 -1.08446703383735 0.837993031513182 5.8573094028756 10.8542236671585 0.539634116864385 0.589676879716759 -5.3621245293427 41.4276263613301 -0.129433544721449 0.897063896920868 TPST1 other 1 1 1 0.539634116864385 -0.129433544721449 5.24922859689078e-25 305.324493424399 27.6924361691228 11.0255555545827 1.22403679353008e-25 -159.181365435974 194.815723078956 -0.817086849665928 0.414238467946901 TOR1AIP2 other 6.78252827004257e-21 1 1.75894087230272e-21 11.0255555545827 -0.817086849665928 0.127346709112761 940.870055001346 470.112004822937 2.00137423709423 0.045850103130874 -478.946803834154 1873.5560839787 -0.255635157084308 0.798329552176868 TM4SF1 other 1 1 1 2.00137423709423 -0.255635157084308 3.54832157133143e-12 69.9021784448817 13.6200410620259 5.1323030618297 3.98297149044646e-07 -44.8845510473936 22.9245009947583 -1.95792925035343 0.05074626142559 OTUD3 other 3.28219745348157e-08 1 0.00393278604966683 5.1323030618297 -1.95792925035343 4.81708716013684e-08 15.2373860149756 3.7939345006955 4.01624909765372 6.74463401034958e-05 -12.5152854605922 7.02403518074316 -1.78178000800789 0.0753428511658274 OTUD7A other 0.00035694615856614 1 0.566414364189158 4.01624909765372 -1.78178000800789 0.517886133336337 73.500258145732 373.139529033796 0.196977946389258 0.843920451822616 -1496.68821694542 1412.8064778287 -1.05937241967183 0.289913668185313 GUSB other 1 1 1 0.196977946389258 -1.05937241967183 3.16881571403962e-34 277.343608670587 41.830229287057 6.63021966165512 8.08016415275355e-11 -826.356780695494 97.3327197453899 -8.49002044592137 1.9674591882747e-16 BRD3 other 4.49750014293643e-30 2.98266812942445e-12 9.33339761284563e-07 6.63021966165512 -8.49002044592137 0.348721586196744 -69.0018939876532 79.9188122854771 -0.863399893146212 0.388298133800753 -213.663006634439 148.190558368399 -1.44181254856518 0.149930679832399 KLF13 other 1 1 1 -0.863399893146212 -1.44181254856518 0.033535094723445 -4.34296967397066 3.50490639072012 -1.23911145971529 0.215854745509005 -94.6046924187182 40.8903459272082 -2.31361927304628 0.0210717792059361 ZFPM2 other 1 1 1 -1.23911145971529 -2.31361927304628 2.65635520870774e-37 62.2879582078427 4.98821710118627 12.4870182961824 1.53101652259048e-31 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53.8398490433695 3.11403352223743 0.001943357887049 -455.275043209289 127.61980324523 -3.56743257419422 0.000392554651103079 MAP3K2 other 0.0011507064203853 1 1 3.11403352223743 -3.56743257419422 2.94157385988886e-14 103.090762790191 15.9211810059192 6.47507008128756 2.18985377395111e-10 -47.7113675420938 31.1105571053845 -1.53360698043675 0.125732201517662 PUSL1 other 2.95216352578446e-10 1 2.4951193900399e-06 6.47507008128756 -1.53360698043675 1.56394027363339e-19 326.287433803705 47.2976933950126 6.89859082722439 1.48030842735158e-11 -286.947678373668 103.166495075462 -2.78140377032077 0.00560225644320862 SF3B5 essential 1.83465833499933e-15 1 1.74765212933128e-07 6.89859082722439 -2.78140377032077 1.89234533703503e-08 18.4529679205386 5.38266714805886 3.42822013937705 0.000653909548681581 -28.3955972387522 10.3003653760249 -2.75675630932915 0.00603524768295251 ZNF35 other 0.000144026403601736 1 1 3.42822013937705 -2.75675630932915 5.0438703746901e-07 2.02928388276599 0.842586013706951 2.40839967641781 0.0163554084336123 -6.89812230574965 1.89416057103822 -3.64178328449139 0.000296739860426144 TIGD4 other 0.00345202488443791 1 1 2.40839967641781 -3.64178328449139 0.00200106568466442 265.55461141611 75.318641716773 3.52574881016439 0.000457637288691608 189.792847209886 122.671234480914 1.54716668510755 0.122400337227068 IFFO2 other 1 1 1 3.52574881016439 1.54716668510755 1.13469763555813e-10 56.8346509100555 27.5928732342977 2.05975834511538 0.0399003676116988 -257.033225215584 50.4256948433749 -5.09726689962217 4.77403502626287e-07 NLGN2 other 9.75726496816435e-07 0.00614800230682132 1 2.05975834511538 -5.09726689962217 0.226889608750474 5.97014957079893 3.49477896054423 1.70830534297059 0.0881543783137597 2.38786700242341 8.98728397626609 0.265693952558901 0.790576325670901 MYO7B other 1 1 1 1.70830534297059 0.265693952558901 2.35781800225579e-30 547.805845516302 162.71986276372 3.36655793713244 0.000814803334248487 -2701.90219508855 293.224060243498 -9.21446279969264 6.74684207421188e-19 CHD3 other 3.23634098989629e-26 1.03483063734262e-14 1 3.36655793713244 -9.21446279969264 0.0914564921946784 28.9187989868363 18.4666989200285 1.56599721000876 0.117933980079471 -34.7102137618764 41.5202802665479 -0.835982164355519 0.403534005420415 TMEM154 other 1 1 1 1.56599721000876 -0.835982164355519 3.80659262253347e-08 -7.00195221989475 10.0072544984284 -0.699687633705564 0.484419840003805 -108.437919473752 19.3018832396651 -5.61799686213586 3.07913510777179e-08 MYRIP other 0.000284162139272124 0.000414420794155005 1 -0.699687633705564 -5.61799686213586 0.00201601244234888 -421.298369788309 320.870365951115 -1.3129862227679 0.189748385497947 -3844.08482318242 1122.32443203555 -3.42511016730736 0.000661545478347649 ALCAM other 1 1 1 -1.3129862227679 -3.42511016730736 1.31435783270282e-19 1188.79709751533 135.844361851525 8.75116995149686 2.73689417105099e-17 -988.695597654479 462.803814299914 -2.13631687359813 0.0331050373685722 YWHAG other 1.54423901764255e-15 1 3.64171138400045e-13 8.75116995149686 -2.13631687359813 6.80223233297897e-06 195.197961446323 39.9398567887183 4.88729748028189 1.35045351520387e-06 74.1785262445575 107.687084526434 0.688834009860753 0.491224120009521 UBE2E3 other 0.0419357623328154 1 0.0128990861359295 4.88729748028189 0.688834009860753 5.00765583121659e-44 164.082697906558 24.0610121232361 6.81944288403814 2.43408777713227e-11 -408.795013632792 43.2805913244089 -9.44522708963647 1.03234374545132e-19 CNTROB other 7.45339493918277e-40 1.58857055550049e-15 2.85567178013158e-07 6.81944288403814 -9.44522708963647 3.21990650602969e-29 303.428231433985 49.4520136368375 6.13581144869615 1.63064087411805e-09 -595.131862994285 88.9535478151447 -6.69036679943373 5.53439641842585e-11 TRAPPC1 essential 4.37553095104374e-25 7.94407261900846e-07 1.79827075597738e-05 6.13581144869615 -6.69036679943373 0.879988107495762 -28.2698128717466 70.4919965485183 -0.40103578073986 0.688554197744974 -86.948943462101 245.234509048373 -0.354554274598238 0.723063507768086 ZPLD1 other 1 1 1 -0.40103578073986 -0.354554274598238 2.61035290346848e-05 4.7206201765331 1.72256875538083 2.74045384939625 0.00633666564763343 -6.60571113883884 3.09853109869122 -2.13188473132608 0.033462890521956 KCNAB3 other 0.152366298975455 1 1 2.74045384939625 -2.13188473132608 0.000885085364668004 5.45341099589569 2.48317356541735 2.19614571926998 0.0285005203762525 -9.96544921149212 5.14104587351816 -1.93840892625074 0.0530874680130665 SERPINA9 other 1 1 1 2.19614571926998 -1.93840892625074 0.000169648749818145 17.094126619068 4.06975707865547 4.200281807659 3.11572056357405e-05 1.91047913001186 30.0834850118804 0.0635059112751527 0.949387022630326 GPR37L1 other 0.893879262791808 1 0.270039501244963 4.200281807659 0.0635059112751527 1.43347053789177e-05 45.7227091209288 10.0111752700516 4.56716697965603 6.12707093744974e-06 81.235493041919 27.8757172314953 2.91420279404095 0.00371353624677604 SIMC1 other 0.086022566978885 1 0.056087207361415 4.56716697965603 2.91420279404095 2.98819768594627e-37 221.382948145398 24.8494977439265 8.90895061247289 7.87559325490178e-18 -370.41632941165 54.527786756382 -6.79316641012017 2.90455683128441e-11 TMEM192 other 4.31884211549814e-33 4.1892423177615e-07 1.05674710294272e-13 8.90895061247289 -6.79316641012017 2.12496466102381e-06 3.71876789406637 0.745637040892676 4.98737011457245 8.41568769587005e-07 -0.5322307056206 2.6617720771763 -0.199953523513256 0.841596946251046 SPDYE5 other 0.0137803958267394 1 0.00813797000190634 4.98737011457245 -0.199953523513256 0.661094973535424 345.997717046675 463.616348314474 0.746301803861287 0.455805737550275 -170.431777214281 958.919863569603 -0.177733076234175 0.858998404779661 SERPINA6 other 1 1 1 0.746301803861287 -0.177733076234175 3.18801887547471e-13 69.4165737470903 13.0931109031089 5.30176321431812 1.68395188805235e-07 -31.1623173759536 28.1138129301194 -1.10843440032171 0.268175104271369 ZNF778 other 3.07420660162026e-09 1 0.00169691831759035 5.30176321431812 -1.10843440032171 9.04328989060137e-22 148.697823421606 23.2457251989306 6.39678143611739 3.53550562739924e-10 -219.281670032475 49.0947915435623 -4.46649559226469 9.75709379712034e-06 NIPA1 other 1.10934037088007e-17 0.117894964350605 4.00643497696882e-06 6.39678143611739 -4.46649559226469 0.000335042055275461 2.36141835875296 1.20904413155868 1.95312834090568 0.0513332218009652 -6.7123929114768 2.75085325981703 -2.44011304038925 0.01501115859232 FOXD4 other 1 1 1 1.95312834090568 -2.44011304038925 4.2451954515676e-11 201.197864352201 36.4432495789914 5.5208541136295 5.2551717567119e-08 -177.815943988984 77.4545179853763 -2.29574656991031 0.0220740875168026 UBE2E1 other 3.73407391919886e-07 1 0.00054522406975886 5.5208541136295 -2.29574656991031 0.0019643487783908 123.678119870796 94.8058109647205 1.30454155301535 0.192601636894549 -347.489053464828 174.883290505065 -1.98697687161121 0.0474270114415839 SIK2 other 1 1 1 1.30454155301535 -1.98697687161121 0.0046706671868801 58.2467532467531 41.280128830174 1.41101190566482 0.158816948486049 310.250745550748 94.6097724639564 3.2792674315853 0.00110782435694214 RNF150 other 1 1 1 1.41101190566482 3.2792674315853 0.000316360424758136 -0.15447827127388 5.8537208637032 -0.026389757023049 0.978956267737948 -72.3847346514974 18.7997922405414 -3.85029439290297 0.000132193799498085 CCDC144A other 1 1 1 -0.026389757023049 -3.85029439290297 0.728557949322378 1.83649852316988 4.19606241898808 0.437671878964271 0.661800791438342 -5.27448191552981 10.3005840088149 -0.512056589317273 0.60882270994068 HOXD4 other 1 1 1 0.437671878964271 -0.512056589317273 3.23452969713357e-05 71.0046652430341 18.7751599239028 3.78184076891071 0.000172953447129269 -23.6498914467134 33.7231478003516 -0.701295489576652 0.483419061249342 CHRNB1 other 0.186988161791292 1 1 3.78184076891071 -0.701295489576652 1.26488657745487e-28 317.757638150539 33.1148543373061 9.59562240298195 3.18951825550598e-20 -270.96152743383 76.2942961379539 -3.55153060123764 0.000416860418891975 USP38 other 1.70835581151055e-24 1 4.39547510791278e-16 9.59562240298195 -3.55153060123764 6.65986729100894e-15 17.9264483814637 9.48985968879702 1.88901089893102 0.0594309414233435 -233.657005535027 31.1310425696884 -7.5055952595219 2.57086891470544e-13 SLC16A5 other 6.8536694291773e-11 3.80000134282611e-09 1 1.88901089893102 -7.5055952595219 6.76595699499061e-18 41.2347181233008 4.75233476849551 8.67672841497966 4.92924110834728e-17 -17.1800799607832 20.8376638890255 -0.824472457770633 0.410039269803722 NANP other 7.61914417205893e-14 1 6.53518786144682e-13 8.67672841497966 -0.824472457770633 0.00101546443159228 0.474968608058066 1.65464640602756 0.287051424599145 0.774182046852535 -8.8322422803382 3.02937145874222 -2.91553624262549 0.00369686073926497 ANKK1 other 1 1 1 0.287051424599145 -2.91553624262549 0.0549027271593217 -9.62750164374851 4.21736096935479 -2.28282608809305 0.0228234542297419 -14.9628307136362 9.91828109181897 -1.50861127801452 0.131975501623771 ADRA1B other 1 1 1 -2.28282608809305 -1.50861127801452 6.52063693510584e-42 14.6580203144403 3.43171956937539 4.2713339531727 2.29625249525325e-05 -68.3134100734485 6.19247898533885 -11.0316741058283 1.16933110699841e-25 ADPRM other 9.63032868945781e-38 1.82240253025702e-21 0.201013943434469 4.2713339531727 -11.0316741058283 0.00379754793674113 20.0011256808536 6.07733045327106 3.29110385466833 0.00106228079122191 24.7160087027271 14.2717053299385 1.73181887737544 0.0838695828733998 FABP6 other 1 1 1 3.29110385466833 1.73181887737544 1.78561018657305e-21 38.1006765450971 9.56881053853503 3.98175681205725 7.76476324856737e-05 -168.632543283778 22.4709262420441 -7.50447673884753 2.51546166217932e-13 PWWP2A other 2.17630169539524e-17 3.71860697519969e-09 0.648202435990404 3.98175681205725 -7.50447673884753 1.37486765129533e-33 12.2366710847056 1.45791332007583 8.3932775125953 4.19834560695656e-16 -18.3247394959802 2.98557278670336 -6.13776343942838 1.62522000922501e-09 USP50 other 1.94048820303823e-29 2.26604425886243e-05 5.47338316778927e-12 8.3932775125953 -6.13776343942838 1.61329908286534e-23 310.55705279111 55.5910913329926 5.58645360874214 3.68452368418819e-08 -743.856426899033 118.943079552228 -6.2538857216355 8.16656848234224e-10 USP47 other 2.03888738092521e-19 1.14625955218156e-05 0.000384885344050299 5.58645360874214 -6.2538857216355 1.32567508707219e-39 420.527274192814 90.6879031045621 4.63708234281204 4.43186386463398e-06 -2035.04010120182 184.555585115056 -11.026705585383 1.1879310102457e-25 PDCD6IP other 1.93813697729954e-35 1.85127168636689e-21 0.0409238309260302 4.63708234281204 -11.026705585383 2.54896313297257e-31 71.373825672006 8.11939555915104 8.79053436330781 2.00687560461789e-17 -147.846052102214 25.2527433559525 -5.8546530972194 8.32104173115681e-09 ZNF212 other 3.53235310967338e-27 0.000114064840050698 2.67496449339518e-13 8.79053436330781 -5.8546530972194 0.00673236167590529 27.2684500250021 10.1055261497501 2.69837014133859 0.00718646814243375 -29.8810532147891 30.3779447161463 -0.983643017788064 0.3257323870195 MRAP other 1 1 1 2.69837014133859 -0.983643017788064 2.2449248697356e-07 28.2475891806919 5.12248262000667 5.51443338633625 5.4271662786999e-08 -2.27414071423587 18.5904533610531 -0.122328416099856 0.902684354758122 FAM161A other 0.00158222304818965 1 0.000562471513124458 5.51443338633625 -0.122328416099856 1.59446218486094e-24 137.268937533723 18.8826854377979 7.26956650238682 1.27781693520585e-12 -324.352911312964 58.7284614671183 -5.52292539613977 5.1968622174365e-08 ZNF282 other 2.04649221426901e-20 0.000694196855005168 1.54973637901765e-08 7.26956650238682 -5.52292539613977 7.55158903398376e-08 224.024106327659 51.0281670696207 4.39020484553187 1.36014525650296e-05 -198.357977251642 103.984580194922 -1.90757107332466 0.056971040051983 GLB1 other 0.000550963935919455 1 0.121338558332629 4.39020484553187 -1.90757107332466 5.61229743318002e-22 33.2836251277329 6.93980255902304 4.79604784785382 2.09031232789727e-06 -90.4943162595802 14.0920534748767 -6.42165575236522 2.93342568461419e-10 GON7 other 6.91322797819115e-18 4.15666419509831e-06 0.0197304580630223 4.79604784785382 -6.42165575236522 0.0021676132565652 197.541693924724 86.4858009123641 2.2840939419049 0.0227518507635697 -353.563434151136 201.851757512466 -1.75159948324602 0.0804082846344119 FAXDC2 other 1 1 1 2.2840939419049 -1.75159948324602 5.42813659410079e-13 281.265577982423 113.39664778818 2.48036942421626 0.0134249265387458 -1354.1215620005 231.07831405501 -5.86001143178732 8.00959477123794e-09 CRTAP other 5.17627105613451e-09 0.000109867611477071 1 2.48036942421626 -5.86001143178732 0.0161306265547671 35.0790826273709 12.6420029200033 2.77480418643676 0.0057134037456474 21.4740255664342 23.3727414746205 0.918763662780081 0.358626384212348 HSPB2 other 1 1 1 2.77480418643676 0.918763662780081 0.48289457138785 78.3336995660656 125.313263452982 0.625103021081695 0.532167501292879 -115.206752989769 239.445862854486 -0.481139041687188 0.63061257584909 SLN other 1 1 1 0.625103021081695 -0.481139041687188 2.30365864309898e-49 113.16095664561 15.4565889735596 7.32121148069513 8.97251064340265e-13 -294.792193781443 28.1326693084254 -10.4786428386714 1.6338551373918e-23 ELP5 essential 3.47691199002929e-45 2.53786718491068e-19 1.09096756913133e-08 7.32121148069513 -10.4786428386714 0.000255118254594997 42.1475793629215 15.3340936477848 2.74861888358236 0.00618310891238635 -57.1617232317578 31.2888767247292 -1.82690237603129 0.0682612204151107 CMTM8 other 1 1 1 2.74861888358236 -1.82690237603129 6.20706747608307e-40 826.872864707619 160.55933634966 5.14995193370061 3.65693909121999e-07 -2996.43067930494 292.235416341346 -10.2534823356419 1.16499725762591e-22 GABARAP other 9.09087102547127e-36 1.8074932452066e-18 0.00361817553685305 5.14995193370061 -10.2534823356419 4.27709160489286e-05 -3.02043726846397 3.13851036413529 -0.962379255770324 0.336293083950989 -36.1776389623924 8.2517392785798 -4.38424406552735 1.40126353837046e-05 LGALS9B other 0.244435785219627 0.167703220272177 1 -0.962379255770324 -4.38424406552735 2.54634217581344e-47 101.251847551962 15.4369814375572 6.55904445836947 1.26180037768374e-10 -281.966872078416 27.1710962836961 -10.3774565860123 3.84046701606001e-23 STX8 other 3.82460594807178e-43 5.96232504243317e-19 1.44968245392085e-06 6.55904445836947 -10.3774565860123 7.41846033227713e-11 375.959925929028 53.9420957356649 6.96969446221302 9.49262924395802e-12 353.34233990739 137.875063540854 2.56277190982175 0.0106595894476673 CDK1 essential 6.44441649064914e-07 1 1.12715479642758e-07 6.96969446221302 2.56277190982175 9.24083458895795e-30 3633.73704509914 454.272196828585 7.99903025205457 7.7369719643521e-15 -3746.28509929138 822.186451841818 -4.55649091626255 6.44202034456472e-06 UBB other 1.2619283714681e-25 0.0786570684071352 9.86773404333467e-11 7.99903025205457 -4.55649091626255 1.8778942688875e-49 119.391644508457 18.3802691033189 6.49564181227895 1.87078675165376e-10 -331.837951842825 35.9283534958084 -9.23610239699792 5.72469898942676e-19 NFRKB other 2.83486918831257e-45 8.78226071967959e-15 2.13681262773893e-06 6.49564181227895 -9.23610239699792 0.103482232566343 670.516323874623 351.184383523215 1.90929994422801 0.0567745335740013 -2721.1815477785 3648.35614038949 -0.745865108302721 0.456086581517772 FABP4 other 1 1 1 1.90929994422801 -0.745865108302721 0.00431664587512111 -4.41083428285944 2.29580258480923 -1.92126026516603 0.0552192078191882 -19.5324519781108 6.16488939907729 -3.16833777764679 0.00161891708196919 FRMPD2 other 1 1 1 -1.92126026516603 -3.16833777764679 8.92886960148912e-08 12.114550407244 7.76143478123425 1.56086480769442 0.119139327646481 -54.217393373173 14.811692998002 -3.66044539138682 0.000276425046675889 PRDM10 essential 0.000647610912196006 1 1 1.56086480769442 -3.66044539138682 3.18583185116471e-05 121.343564776083 33.1290548282145 3.6627535981721 0.000274051945758354 -255.35598297106 119.775831825256 -2.13194915100739 0.0334608748641652 B3GNT2 other 0.184364089226902 1 1 3.6627535981721 -2.13194915100739 0.000543276177909652 -649.563130078733 830.562256777124 -0.782076388348381 0.434508701450651 -6268.53841566782 1650.36065393462 -3.79828396946026 0.000162059440001319 FOS og 1 1 1 -0.782076388348381 -3.79828396946026 9.05483392712254e-37 1065.41958797964 187.285924011035 5.68873284848075 2.08691698606999e-08 -3379.92935779356 371.055050098604 -9.10897010267176 1.55880855917323e-18 TMED10 other 1.30489211723763e-32 2.38902999778889e-14 0.000220503648748155 5.68873284848075 -9.10897010267176 1.99182595103068e-15 107.355871475908 15.4372117836609 6.95435632939467 1.04681698107598e-11 -144.159894656014 40.0285525456048 -3.60142661895585 0.000346239382637463 SETMAR other 2.08444585775361e-11 1 1.24173430295233e-07 6.95435632939467 -3.60142661895585 1.10362614255396e-06 100.965541154608 25.8650255383368 3.9035546670912 0.000106805611726383 -117.102747616207 59.8611936560452 -1.95623809790805 0.0509531541787727 SMAD1 other 0.00733313875214032 1 0.880078240625398 3.9035546670912 -1.95623809790805 0.629842100753149 -0.0635308010339794 128.421513148441 -0.000494705283222641 0.999605467404608 -514.429021005529 550.902508772344 -0.933793208079421 0.350833400503927 CST5 other 1 1 1 -0.000494705283222641 -0.933793208079421 0.138633711171803 -29.3698218375125 21.7853171679761 -1.34814754410303 0.178183572118775 -163.301294384962 93.4546369062544 -1.74738568134155 0.0811463542916525 CST2 other 1 1 1 -1.34814754410303 -1.74738568134155 0.565906089702866 -0.320743362615191 2.50871575421139 -0.12785161574274 0.898313823495569 -4.96722032085317 4.81959959849884 -1.03062925028052 0.303174394246058 EMX2 other 1 1 1 -0.12785161574274 -1.03062925028052 0.236902138933781 -4.61512553136025 46.0173143730212 -0.100291066400563 0.920150961284288 -329.80594972086 197.405039962114 -1.67070683597621 0.0953666348909099 CST1 other 1 1 1 -0.100291066400563 -1.67070683597621 6.2599022564e-05 0.805043183792031 10.1966554824773 0.0789516901081418 0.937100134907185 -142.364924484073 34.0177012058395 -4.18502483817557 3.32549392917413e-05 TCAF2 other 0.34930254590712 0.387752592141704 1 0.0789516901081418 -4.18502483817557 0.0222794356112642 -12.4810426860057 36.9361149720102 -0.337908919101634 0.735562182725269 -322.970504977694 117.653905770617 -2.74508953070688 0.00624943677890822 SEMA3E other 1 1 1 -0.337908919101634 -2.74508953070688 0.00575100778909045 85.4096429850406 27.1458101580736 3.1463287515712 0.00174465020740463 -211.797197912389 242.029243909953 -0.875089284628713 0.381915099162734 LRRN2 other 1 1 1 3.1463287515712 -0.875089284628713 3.64626371028779e-05 179.606735825584 48.5302848790102 3.7009206987628 0.000237109381926823 -712.546385129182 311.810824489801 -2.28518809856933 0.0226929630710394 SLC30A1 other 0.209769551252857 1 1 3.7009206987628 -2.28518809856933 0.000140198855414728 10.4427350144699 9.18292620011825 1.13719034509234 0.2559640072957 88.0796257087944 20.8808073512688 4.21820977642622 2.88865345257012e-05 DCLK2 other 0.747119700505084 0.338405751968589 1 1.13719034509234 4.21820977642622 0.578581734024327 -4.41463451335942 5.50841699646893 -0.801434335161869 0.423231447674205 -12.2401730097242 14.3303284946856 -0.85414462161586 0.39340221588695 ZNF804A other 1 1 1 -0.801434335161869 -0.85414462161586 4.14427827118304e-14 228.940793055569 40.0368048967793 5.7182583287006 1.78794262327511e-08 -583.873437806732 134.664312166764 -4.33576965130659 1.73491054663403e-05 GPRC5C other 4.1343320033322e-10 0.206419656838517 0.000189450400362231 5.7182583287006 -4.33576965130659 0.00661665755837958 27.3487354258576 9.63310637812054 2.839035961232 0.00469321722178412 -26.6050178618956 30.667660328433 -0.867526820662912 0.386033835621377 TMEM182 other 1 1 1 2.839035961232 -0.867526820662912 0.0667461058765315 259.873465904693 144.534953678089 1.7979973652843 0.0727421460108225 -663.148941262492 615.074833337968 -1.07815977067966 0.281449241853477 VSTM2A other 1 1 1 1.7979973652843 -1.07815977067966 2.66431469278e-11 6689.59268042954 1462.42114397571 4.57432710678904 5.9241967154216e-06 -17618.8136848464 4346.43210441009 -4.05362680506834 5.78029131711123e-05 KRT8 other 2.36617787865792e-07 0.663577443204369 0.0542893387001236 4.57432710678904 -4.05362680506834 3.86288224570582e-07 37.3526475406248 6.93082884941985 5.38934784744416 1.05802470920942e-07 43.574619925631 12.5370062213731 3.47567985180905 0.000550545163217137 ADORA2B other 0.00267272822580386 1 0.00107844458609716 5.38934784744416 3.47567985180905 5.76116104072137e-12 74.5650169621673 37.6956453763499 1.97808039145416 0.0484303373797792 -431.88820309865 75.0955036518236 -5.75118591788234 1.48888311816357e-08 MGMT other 5.28644137096593e-08 0.000202458326407882 1 1.97808039145416 -5.75118591788234 0.148595990717175 5.73767827816979 4.76254162896741 1.20475131246544 0.22882125555535 25.0958354350958 13.8556592013244 1.81123359563413 0.0706540918812081 METTL7B other 1 1 1 1.20475131246544 1.81123359563413 0.292012788691402 18.3914026574809 41.1772719251064 0.446639658181615 0.655312675679437 200.532968201715 127.672645183117 1.57068076653457 0.116837176549864 KRT86 other 1 1 1 0.446639658181615 1.57068076653457 9.14458136114366e-36 226.553138255185 25.5235668149672 8.87623347855648 1.02289858155461e-17 -421.835702406286 61.8895480806992 -6.81594413738884 2.5150908212945e-11 HARS essential 1.31169875044245e-31 3.63028209145648e-07 1.36976349055978e-13 8.87623347855648 -6.81594413738884 2.71335170763224e-09 80.1269371463095 14.3740035839268 5.57443419841 3.92999709353022e-08 -14.1314315297843 32.0268964236557 -0.441236370294893 0.65921882408159 NFXL1 other 2.17041003093503e-05 1 0.000410134496680813 5.57443419841 -0.441236370294893 0.691469504020693 19.3188299160415 29.7190438894952 0.650048836963767 0.515933081740715 65.2477363819766 91.370982797382 0.714096908935143 0.475471297584357 KRT75 other 1 1 1 0.650048836963767 0.714096908935143 0.0219181594174641 26.8011901744363 11.9922128233943 2.23488280012449 0.0258465434595014 -72.6719580682008 59.3155099349631 -1.22517631809762 0.221060271596178 DENND5B other 1 1 1 2.23488280012449 -1.22517631809762 0.253057062002237 97.5319713609133 75.9169053258189 1.28472006257799 0.199436894395373 258.518793645143 179.770713628972 1.43804732387445 0.150995628613958 CD14 other 1 1 1 1.28472006257799 1.43804732387445 1.66171983035331e-06 15.9259290115814 6.40213929615824 2.48759489209148 0.0131599818878842 -52.0206625489723 15.2236319510018 -3.41709933059366 0.000680348320722927 DNAJC18 other 0.0108759562896624 1 1 2.48759489209148 -3.41709933059366 0.439839982157147 72.7744553701894 120.533948317655 0.603767290343792 0.546248208134395 465.048049938412 372.152617687139 1.24961649558883 0.211973108790185 KRT6C other 1 1 1 0.603767290343792 1.24961649558883 3.68938328066968e-28 78.1988050846592 11.1034122450862 7.04277238010919 5.72652295186881e-12 -121.863531296453 21.8666557366194 -5.57303013155196 3.94719517794722e-08 RIOX1 other 4.96000688253232e-24 0.000529595177025179 6.83517779535061e-08 7.04277238010919 -5.57303013155196 2.47554289261027e-11 4.54797485830359 2.23450872656759 2.0353354651202 0.0423039822486217 -30.0540961927633 5.26812328120377 -5.70489614394444 1.91844454150523e-08 SPATA24 other 2.20174784868758e-07 0.000259872497592299 1 2.0353354651202 -5.70489614394444 2.09957624927082e-18 464.472399946482 57.0195100236493 8.14585042477283 2.69146292174648e-15 -1142.96849037499 340.989765079317 -3.35191436056484 0.000859494668344942 RALGAPB other 2.39519658516815e-14 1 3.45799156185988e-11 8.14585042477283 -3.35191436056484 1.27294849890268e-20 119.658408720263 19.8577391105326 6.02578209202056 3.10063539771147e-09 -346.751688609352 57.9869486748453 -5.97982298661236 4.04381226113942e-09 PYM1 other 1.52550148108498e-16 5.58693101999022e-05 3.38341334598276e-05 6.02578209202056 -5.97982298661236 0.535164702427432 -62.0530199674784 55.6968192669304 -1.11412143070658 0.265720902416933 -64.3145821171388 131.094783130968 -0.490596044946245 0.623910738504826 MZB1 other 1 1 1 -1.11412143070658 -0.490596044946245 0.870955233188917 2.28382369860774 191.190636459405 0.0119452696057773 0.990473635784197 290.565257998899 569.648496996789 0.510078161411417 0.610202454580249 KRT4 other 1 1 1 0.0119452696057773 0.510078161411417 0.00110982236169284 3.11661391554297 4.458439456371 0.699036949148071 0.484828243987138 -33.1887087121012 10.4933763620762 -3.16282458256691 0.00164980733695822 SLC23A1 other 1 1 1 0.699036949148071 -3.16282458256691 0.109026246519231 -11.6801133007818 40.4353523462944 -0.288858947011308 0.772799157734354 -267.980597447912 127.362849591534 -2.10407193547689 0.035829652855896 NPAS2 other 1 1 1 -0.288858947011308 -2.10407193547689 0.00793551227193698 -226.517533067693 91.5384558807519 -2.47456143855845 0.0136449227986523 -679.545173016519 286.888948954459 -2.36866974309418 0.0182018884301424 LONRF2 other 1 1 1 -2.47456143855845 -2.36866974309418 3.047465748342e-27 132.230082447023 23.5367920886405 5.61801633583026 3.07628364060192e-08 -430.049413779669 57.5677883412614 -7.47031328058565 3.17750790351556e-13 NUDT9 other 4.05587216446836e-23 4.69286142270213e-09 0.000322640628226329 5.61801633583026 -7.47031328058565 2.02892725285757e-12 454.364528638451 67.4172036025502 6.73959322485551 4.08544795190438e-11 -279.428109585049 197.633778913328 -1.41386817132911 0.157976851639092 PA2G4 other 1.89339491236669e-08 1 4.75668705040227e-07 6.73959322485551 -1.41386817132911 6.83091746534668e-05 265.282200350123 63.3594229624273 4.18694154628646 3.29659342592442e-05 58.4961623847864 139.227666926163 0.420147544494936 0.674543263912114 ELOVL6 other 0.379730701898622 1 0.284957535736907 4.18694154628646 0.420147544494936 0.000158133071645619 -8.68327118935906 17.0265226487916 -0.509985002132853 0.610268052739704 202.974880522963 52.0781904487292 3.89750255863423 0.000109270480002642 KRT83 other 0.837947146650134 1 1 -0.509985002132853 3.89750255863423 0.35826665264593 192.038144410682 185.653032884443 1.03439271326213 0.301411372556798 -666.953526893009 805.232633410503 -0.828274338644445 0.407877713307282 PFKFB3 other 1 1 1 1.03439271326213 -0.828274338644445 0.000612326444159442 17.9127378344937 4.80120303253913 3.73088530376531 0.000210777662159223 0.251065133838723 25.4545330265607 0.0098632779307618 0.992133973135855 TMC7 other 1 1 1 3.73088530376531 0.0098632779307618 4.6199565959399e-15 1383.81815973058 191.95968258516 7.20890002053775 1.89245260996412e-12 -2079.65102235194 995.470731485887 -2.08911317688642 0.037160781974708 ARL6IP1 other 4.77934509849983e-11 1 2.28778596018563e-08 7.20890002053775 -2.08911317688642 0.46500089601968 17.973973325197 15.7150094525102 1.14374562608525 0.253247418312653 -4.73383986157066 48.997771417821 -0.0966133708654535 0.923070097357743 SERPINB9 other 1 1 1 1.14374562608525 -0.0966133708654535 0.0216444756881228 33.6477949750364 15.7384624313909 2.1379340657779 0.0329687193986988 105.1193097595 45.6066593330635 2.30491141637493 0.0215484949195941 SMAGP other 1 1 1 2.1379340657779 2.30491141637493 2.30016338806682e-06 144.481031012311 32.4052784840873 4.45856470831623 1.00846975107085e-05 478.147918412364 148.161167468164 3.22721484031979 0.00132757819021643 IRX1 other 0.014870556303852 1 0.0908429551764626 4.45856470831623 3.22721484031979 0.271905749993512 132.244658303967 141.492162442534 0.93464299379605 0.350393180723753 -277.33732477198 316.947433943978 -0.875026250633728 0.381951544403111 CDH2 other 1 1 1 0.93464299379605 -0.875026250633728 0.126649440971638 -40.6645091473381 92.1952466799054 -0.44106947604926 0.659343933366167 -863.575895287879 425.250451921476 -2.03074656684278 0.0427831734810614 IRX2 other 1 1 1 -0.44106947604926 -2.03074656684278 0.00137018286316568 -30.8089339073537 62.2367215096454 -0.49502822706654 0.62079381263545 -540.47797147834 152.384393170897 -3.54680660028092 0.000425962558174492 EMB other 1 1 1 -0.49502822706654 -3.54680660028092 7.79689303387429e-05 133.422561189625 30.5211984721087 4.37147189064515 1.47937015990374e-05 32.4173301561607 101.415648906315 0.319648205240069 0.749357971524982 SIX2 other 0.429920681887829 1 0.131435096188404 4.37147189064515 0.319648205240069 0.00174827924065064 74.4692415930627 28.2744543394849 2.6337994254081 0.00868931291903435 -61.9472969369117 64.3600119759038 -0.962512203386547 0.336229653872437 DLGAP1 other 1 1 1 2.6337994254081 -0.962512203386547 1.86706041100386e-05 309.210509753735 68.3537419069613 4.52368079825991 7.48063246724671e-06 -21.2460936818105 202.134727469755 -0.105108577569827 0.916328755223911 STAT2 other 0.110754023580749 1 0.0680363522896088 4.52368079825991 -0.105108577569827 1.9212100509484e-21 69.8291629184751 10.0381297055727 6.95639177482529 1.00430278593122e-11 -108.28353653495 24.0291908709453 -4.50633303120832 8.07669205606209e-06 NUDCD2 other 2.34080232607553e-17 0.0980591182526498 1.19180611606458e-07 6.95639177482529 -4.50633303120832 3.66875867615508e-11 56.1029518477595 22.3889071729869 2.50583699393109 0.0125060377546292 -357.480715373317 66.3113433274246 -5.39094365210171 1.04466190013706e-07 IRF2BP1 other 3.23621202823639e-07 0.00138177429531128 1 2.50583699393109 -5.39094365210171 1.06938052985542e-16 711.373465502162 126.733441808474 5.61314721158782 3.16969759739628e-08 -1223.49292425575 295.085961620026 -4.14622545084409 3.92021124953489e-05 HSPA4 other 1.16476927311852e-12 0.455136526071001 0.00033218430820713 5.61314721158782 -4.14622545084409 0.544133538618364 -1.09587476634675 6.26474662433251 -0.174927228834815 0.861201542868194 -20.3746022978211 18.7628349887078 -1.08590212033967 0.278000612149793 FOXA3 other 1 1 1 -0.174927228834815 -1.08590212033967 3.43137589931239e-35 154.364977556804 11.5714225806158 13.3401901521938 9.60354719605684e-35 -99.2410477090555 79.290742562103 -1.25160951332152 0.211323057480849 COMMD5 other 4.90137733457782e-31 1 1.43400166731521e-30 13.3401901521938 -1.25160951332152 0.00495846111465903 -30.3916446317328 26.9874373661505 -1.12614044154678 0.260601710558762 -204.940416371232 62.6015211102373 -3.27372902026366 0.00112869531730389 SGCD other 1 1 1 -1.12614044154678 -3.27372902026366 0.364257351598987 3.45535895345926 10.5136456083359 0.328654691453516 0.742544115405788 43.5910445472821 30.6790635181615 1.42087272388471 0.155930935446794 GTSF1 other 1 1 1 0.328654691453516 1.42087272388471 0.0492693712420455 6.29518379405368 4.15591032972915 1.51475448087061 0.130419680301727 -17.227493591511 12.3613771533083 -1.39365487986106 0.163995131620863 DPY19L2P2 other 1 1 1 1.51475448087061 -1.39365487986106 1.56819629094328e-33 56.6704717277014 4.40643254629756 12.8608508430063 1.02435123597925e-32 -48.7965577670968 30.1813833310954 -1.61677671403558 0.106586211060093 ZNF16 other 2.21288178615006e-29 1 1.5201372341932e-28 12.8608508430063 -1.61677671403558 3.28242042824576e-30 126.982633187626 20.3770843784526 6.23163897392022 9.301924848901e-10 -507.706808749034 60.6097834895429 -8.37664778717827 4.72237183093116e-16 ARMC10 other 4.49888543895363e-26 7.14305963146647e-12 1.03697858215548e-05 6.23163897392022 -8.37664778717827 2.66676410656268e-19 152.964074566721 21.3282045417045 7.17191521056638 2.43871610010588e-12 -182.098651005564 46.8908384759722 -3.88345904923143 0.000115696644524731 RNF34 other 3.11078033030536e-15 1 2.93962838706763e-08 7.17191521056638 -3.88345904923143 1.48189107429724e-05 32.6853918606718 7.06080954611685 4.62912809744987 4.60064516231778e-06 -10.1511892660388 24.8683097731083 -0.408197797062024 0.683289672968185 ACYP2 other 0.0888097320826336 1 0.0424363509772192 4.62912809744987 -0.408197797062024 5.93357423560433e-19 263.650752597883 35.3243747286997 7.46370614123501 3.44827510300316e-13 -170.725827196592 75.2486298912034 -2.26882306619313 0.0236780649724748 TRABD other 6.84971809758164e-15 1 4.23827492910118e-09 7.46370614123501 -2.26882306619313 1.05234269995123e-05 -1.9135755390843 4.95490290416315 -0.386198393005138 0.699501577738413 -42.4163264713488 10.0459512581616 -4.22223096462754 2.83756382348214e-05 TMEM133 other 0.0638772018870394 0.332562480112107 1 -0.386198393005138 -4.22223096462754 8.67239211745976e-05 22.1093962157037 38.8199845372892 0.569536450857321 0.569231190150404 -482.836293161917 120.047525429096 -4.02204286540747 6.59990075552848e-05 ATF7 other 0.474900192352096 0.754170659334239 1 0.569536450857321 -4.02204286540747 0.0479591739025624 33.8899627996643 18.6729868793605 1.81491922093746 0.0700930395023004 -62.2572912133959 57.9916954128147 -1.07355528701509 0.283503320687137 RASA4B other 1 1 1 1.81491922093746 -1.07355528701509 6.23861351700355e-11 212.374992519268 57.386601678288 3.70077659781725 0.000237240691242898 -439.940321077213 117.873144987757 -3.73232020849963 0.000210072400899861 SOCS6 other 5.43819940277199e-07 1 1 3.70077659781725 -3.73232020849963 0.0987095032195941 36.0840797931037 16.7950045874378 2.14850074051742 0.032115558016578 18.3851834362188 34.9374174496804 0.526231896295672 0.598941957986641 CAVIN4 other 1 1 1 2.14850074051742 0.526231896295672 0.0857274816496994 7.21016359218824 7.98557003615698 0.902899049102585 0.366978357410976 -41.1960368738927 24.8412049864794 -1.65837514308646 0.0978171527141202 ZNF296 other 1 1 1 0.902899049102585 -1.65837514308646 0.501972353463352 12.8750694475477 13.7690296748471 0.935074566007184 0.350178946713696 49.316721041856 54.5973795946205 0.903280000029804 0.366790781142994 HOXB9 other 1 1 1 0.935074566007184 0.903280000029804 5.14198136992134e-38 158.534136359896 11.6790308177417 13.5742544765843 2.59307243206837e-36 -68.6015898563405 62.6608171244145 -1.094808414645 0.274089558815173 POLH other 7.46410015657782e-34 1 3.88883072637294e-32 13.5742544765843 -1.094808414645 1.67030203933785e-05 -31.8700655195634 27.0218224403592 -1.17941954469966 0.238744807748248 -293.361032674124 62.5769152773532 -4.68800725273674 3.48888605381679e-06 SYT9 other 0.0995834075853228 0.043171476029929 1 -1.17941954469966 -4.68800725273674 0.00626405831292232 -36.6560908432169 53.2398804796937 -0.688508135498125 0.491427435313758 -492.51884680148 153.995248442225 -3.19827301026278 0.00146327632540504 KCNS3 other 1 1 1 -0.688508135498125 -3.19827301026278 5.74726251562604e-11 965.817940025818 146.969314231779 6.57156186020349 1.17256876190519e-10 -535.841587318468 536.300919560164 -0.999143517706305 0.318171848617915 KIF5B other 5.02138325990247e-07 1 1.34821956243859e-06 6.57156186020349 -0.999143517706305 0.000540289641339352 10.1032054766121 8.16595423533795 1.23723513326719 0.216538540684821 -77.5159325400352 25.2253290601552 -3.07294039079458 0.00222677692959052 GPR37 other 1 1 1 1.23723513326719 -3.07294039079458 2.45218785294081e-09 136.06236647101 21.222144673623 6.41133912540526 3.23627483205295e-10 128.711031894297 46.4085217964218 2.77343528541824 0.00574562706932627 CDCA4 other 1.967880751985e-05 1 3.67220105193049e-06 6.41133912540526 2.77343528541824 0.308200296414254 15.4289024711923 24.0728596726635 0.640925202945994 0.521858606465174 -247.085999531703 189.32414267994 -1.30509503983024 0.192447851593901 SDR16C5 other 1 1 1 0.640925202945994 -1.30509503983024 1.04126367722605e-44 124.073873505976 7.97442505917222 15.5589741687103 5.57256022273229e-45 -35.831505886077 62.7389478638165 -0.571120605398966 0.568168485758623 CHCHD7 other 1.55314890095038e-40 1 8.48533745115446e-41 15.5589741687103 -0.571120605398966 0.0271056438412288 -303.887477315268 163.104108451316 -1.86315035348098 0.0629797934380476 -916.928909756287 358.07715850457 -2.56070203859313 0.0107148419114418 HTRA3 other 1 1 1 -1.86315035348098 -2.56070203859313 2.12094167172818e-12 111.050550515526 14.7761514451792 7.51552601010707 2.33584260157502e-13 61.9932897322792 53.0226432808124 1.16918519893393 0.242839193581911 FOXN2 other 1.97756601471935e-08 1 2.88499919720531e-09 7.51552601010707 1.16918519893393 0.379050362326554 142.795704495691 106.229602235005 1.34421763323366 0.179440372956822 33.0174141040193 324.210402599165 0.101839465480816 0.91892176340547 LMOD2 other 1 1 1 1.34421763323366 0.101839465480816 0.124088469636875 24.4618043623889 13.3826760594151 1.82787091713091 0.068113469091296 -6.75891244041077 31.7927718217642 -0.2125927389503 0.831723834864402 CELP other 1 1 1 1.82787091713091 -0.2125927389503 1.34580497658556e-25 211.71415074602 20.9951233684616 10.0839679305744 6.82475865106725e-22 -558.574306129264 147.800433609726 -3.77924673485199 0.000176274019583164 USP32 other 1.75277640150503e-21 1 9.53964764246181e-18 10.0839679305744 -3.77924673485199 0.109274490420144 174.060363192862 90.8498578533672 1.91591233388386 0.0558972042717798 -30.9267014126951 215.828940934407 -0.143292652407047 0.886111828115466 CEL other 1 1 1 1.91591233388386 -0.143292652407047 5.80364493614115e-37 75.0977258731099 5.40030324426406 13.9062053511301 1.92580250436943e-37 -8.1878422099119 37.1079541648465 -0.220649248771265 0.825454904936986 PPM1D other 8.37407927835806e-33 1 2.89409600356638e-33 13.9062053511301 -0.220649248771265 9.25422686845535e-11 11.6615153877882 14.1218822877901 0.825776277562573 0.409295011792043 -161.246448384613 27.5600184829472 -5.85073803504105 8.48228062795973e-09 GPR27 other 7.99287574628488e-07 0.000116232691444932 1 0.825776277562573 -5.85073803504105 8.17671314703102e-12 135.104640725557 20.7837289840688 6.50050050350048 1.81297659889379e-10 -170.162043975125 88.414086252817 -1.92460332043191 0.054800209058635 KBTBD2 other 7.44898567694526e-08 1 2.07186965721582e-06 6.50050050350048 -1.92460332043191 2.28056171228214e-05 137.47522037038 34.6189259822997 3.97110009827195 8.1422759216264e-05 -222.852878711428 120.326069367372 -1.85207478215737 0.0645709527020907 RIOX2 other 0.133777750042471 1 0.678495852549128 3.97110009827195 -1.85207478215737 2.88804902198853e-15 106.933597397169 16.1854642077623 6.60676740713344 9.37207096250278e-11 -109.601953220373 36.3833201622029 -3.01242307551232 0.00271226681830584 TRIAP1 essential 3.00761425149886e-11 1 1.08059978197657e-06 6.60676740713344 -3.01242307551232 4.36076321997155e-22 186.015899739956 20.9210822570851 8.89131343465563 9.08776146206647e-18 -186.163918907538 57.818274615024 -3.21981103979819 0.00136002028932205 LSM3 essential 5.38336219505488e-18 1 1.21757828068767e-13 8.89131343465563 -3.21981103979819 1.21322041778785e-30 144.643799562943 65.6446259102448 2.20343703017995 0.0279830369896063 -1225.74792334234 127.067263735018 -9.64644934747692 1.98027866474637e-20 KIAA0232 other 1.66963393895964e-26 3.05339167317243e-16 1 2.20343703017995 -9.64644934747692 3.19432135752218e-09 329.468378856708 53.0900827844072 6.20583660030523 1.09522259794791e-09 -790.428082652511 600.950597619483 -1.31529627524059 0.188976949933314 MTSS1 other 2.54555468980942e-05 1 1.21723039535931e-05 6.20583660030523 -1.31529627524059 3.8712013486115e-08 357.486267569918 60.3203338558461 5.92646367681321 5.53215438672053e-09 164.426180507149 152.188194816022 1.08041350188772 0.280442168929566 TMEM43 other 0.000288830332619904 1 5.98247175379958e-05 5.92646367681321 1.08041350188772 9.84221377651659e-46 272.203277360692 17.4431780297368 15.6051424170897 1.71978250567308e-45 -555.382896083365 199.256727703317 -2.78727299441704 0.00550499856819168 RNF139 other 1.47278886951794e-41 1 2.62146447339748e-41 15.6051424170897 -2.78727299441704 0.251488904284727 -9.21975334619723 309.283035462214 -0.0298100842563789 0.976229550606433 -2289.69867317037 1390.21099199217 -1.64701522744345 0.100137760685664 RPS9 other 1 1 1 -0.0298100842563789 -1.64701522744345 0.0958866206125625 -3.69077450398531 2.34038389497772 -1.57699534333039 0.115374716599699 -9.4109304951157 4.5287953981688 -2.07802068049287 0.038173212455001 CYTL1 other 1 1 1 -1.57699534333039 -2.07802068049287 3.41075520924428e-26 331.917965454482 29.1803996679425 11.3746888058948 5.64224696728803e-27 77.7615817522351 121.542708052828 0.639788128782157 0.522586804973605 TSEN34 essential 4.47968589182144e-22 1 8.17279473211671e-23 11.3746888058948 0.639788128782157 0.545453349421207 182.681145117309 368.963763855968 0.495119475170528 0.620716815150268 -1065.8094671399 1208.63630340376 -0.881828110026456 0.378261387941567 TRH other 1 1 1 0.495119475170528 -0.881828110026456 1.3284997643398e-06 98.1297176404797 19.1715823217529 5.11849861913263 4.33666353068638e-07 30.0097944305254 70.8751934604877 0.423417460542886 0.672165107074545 GSTA4 other 0.00877474094346438 1 0.00427204724407915 5.11849861913263 0.423417460542886 1.11968633405503e-24 66.2881948892899 10.1433992483702 6.53510655216896 1.46596455845856e-10 -71.5139214758442 19.9000441633154 -3.59365642050564 0.000355731136639916 MSANTD4 other 1.44058843739521e-20 1 1.67999538399351e-06 6.53510655216896 -3.59365642050564 4.34171049703056e-08 191.429976137461 35.8262247571554 5.34329188841556 1.35966781282663e-07 -226.710959354305 144.888064773403 -1.56473177903831 0.118244928989412 NDUFA3 other 0.000322241753089608 1 0.00137734349439338 5.34329188841556 -1.56473177903831 0.828144586723668 1.8326343728885 5.44630124264182 0.336491554771132 0.73663391068452 -9.84010031131934 22.0258777632369 -0.446751789739945 0.655237465757871 OSCAR other 1 1 1 0.336491554771132 -0.446751789739945 0.0126310597399041 25.7043033261958 10.6284454718938 2.41844429593857 0.0159217495333714 -40.2458705939637 43.6393816482078 -0.92223741661602 0.356822796372603 PAQR8 other 1 1 1 2.41844429593857 -0.92223741661602 4.92666354357838e-09 13.9213578969875 7.54898707800781 1.84413587586395 0.0657119530060868 -90.3002754235453 18.0131121451073 -5.01303021355323 7.28006513349042e-07 NUDT6 other 3.88418153775719e-05 0.00930683526665415 1 1.84413587586395 -5.01303021355323 2.33926423729705e-19 473.095009950285 57.0174376860696 8.29737408676769 9.42153334585199e-16 -798.940895323974 231.184728531273 -3.45585497969387 0.000593951079393364 TANC2 other 2.73343026128161e-15 1 1.22027699895475e-11 8.29737408676769 -3.45585497969387 0.349089333148801 3.75188173494739 3.36446488985938 1.11514961747876 0.26528234245476 -8.27280685036038 14.2954526771578 -0.578701985672633 0.563031562162515 PKHD1 other 1 1 1 1.11514961747876 -0.578701985672633 2.26290529373036e-16 32.3799950599397 5.2503075750173 6.16725679349042 1.3742640052311e-09 -70.5321062170039 15.8258861228074 -4.45675557562346 1.01483774083371e-05 DNAJC24 other 2.44190110246443e-12 0.122470618563812 1.52117282739031e-05 6.16725679349042 -4.45675557562346 2.3265983758606e-19 115.943065417033 13.9970437658146 8.28339664838405 9.357612900887e-16 -202.435707306762 59.8338346139991 -3.38329823941116 0.000767778690581701 ZNF160 other 2.7188628620307e-15 1 1.2121851751809e-11 8.28339664838405 -3.38329823941116 1.13382790338323e-08 33.0012353929965 6.55374753941429 5.03547553434532 6.4890277457871e-07 -71.791151075737 27.9243165432684 -2.57091882497813 0.0104071188009484 ZNF415 other 8.74067930718135e-05 1 0.00631641960774917 5.03547553434532 -2.57091882497813 0.0920411507450461 -27.69984190205 20.830052553705 -1.32980182506179 0.184138834357249 48.9760380074456 46.1244559819268 1.06182364571706 0.288785182182829 CAVIN3 other 1 1 1 -1.32980182506179 1.06182364571706 0.293698420433243 0.91911700830678 2.30853568797291 0.398138531318891 0.690686900533645 -9.75221512435852 7.48416403379892 -1.30304668367996 0.19311935954602 CEACAM3 other 1 1 1 0.398138531318891 -1.30304668367996 0.0251927959488159 14.6926016752924 5.45185939726025 2.6949707622093 0.00726295034488127 -21.3395396821136 61.3475846008221 -0.347846452651172 0.728093606261144 HAS2 other 1 1 1 2.6949707622093 -0.347846452651172 0.0147469900310736 -6.66578759782238 37.1402584900188 -0.179476069064349 0.857630611913304 -186.751951354415 74.6363921172543 -2.50215673690424 0.0126358114875207 PDGFD other 1 1 1 -0.179476069064349 -2.50215673690424 0.0292758988160005 -97.6916873458577 45.272305244504 -2.15786863112559 0.0313832140485563 -202.101748496859 87.1163170976878 -2.3199069385616 0.0207220305777679 S1PR1 other 1 1 1 -2.15786863112559 -2.3199069385616 0.151402746565459 21.5989307161665 11.7565217289235 1.83718715570684 0.0667305871361648 29.1610489815939 22.0400291924728 1.32309484379236 0.18636276770927 PYGO1 other 1 1 1 1.83718715570684 1.32309484379236 1.94332544391955e-25 152.24333350631 19.13220388291 7.95743838180099 1.02671477961366e-14 -233.942190516141 50.2055500346309 -4.65968783042456 3.98701368289677e-06 LRRC8E other 2.52651740963981e-21 0.0492077228743119 1.30649455705838e-10 7.95743838180099 -4.65968783042456 0.002909418277163 61.4510799869245 17.8806609006222 3.43673426437979 0.00063609850762617 43.9670238484392 175.824449567463 0.250062058812641 0.802638497211669 PKIA other 1 1 1 3.43673426437979 0.250062058812641 3.46751789208098e-08 1.4046088565329 0.969773200224394 1.44838902148244 0.148087589532455 -10.1038405928428 2.46546774885489 -4.09814348516041 4.80350069560113e-05 XKR6 other 0.000259509039043341 0.554948435362799 1 1.44838902148244 -4.09814348516041 2.92716758772457e-31 65.16528616209 5.26159309313256 12.3850866094423 4.23501306877246e-31 -51.4900409041101 39.5605036047866 -1.30155170466233 0.193638351422664 TSNARE1 other 4.05471254251608e-27 1 6.25299679604253e-27 12.3850866094423 -1.30155170466233 0.496958873685053 -3.91800179538904 5.07567224759607 -0.771917807979953 0.440498918813225 -21.3767858947728 21.18580603009 -1.00901451964639 0.313417079511238 FPR1 other 1 1 1 -0.771917807979953 -1.00901451964639 9.62092778649313e-05 103.32191669367 27.4845458488677 3.75927320254143 0.000188884640927572 -116.922765664652 87.0576710504672 -1.34304954697067 0.179817012164938 FEZ2 other 0.523898581687916 1 1 3.75927320254143 -1.34304954697067 0.0337368849366403 17.0060369535553 7.66230777146033 2.2194405994624 0.0268699378875515 0.429864239646716 19.4175441833142 0.0221379302958458 0.982346077369977 SOX7 other 1 1 1 2.2194405994624 0.0221379302958458 4.05893349402894e-11 138.448738366953 23.031142496883 6.01137083779888 3.56861454977686e-09 -178.029531020284 83.511092381058 -2.13180699646392 0.0335135068182032 C11orf24 other 3.57429683484189e-07 1 3.88408007597713e-05 6.01137083779888 -2.13180699646392 1.25736179310766e-09 37.266244090519 5.76549597898929 6.46366665180676 2.27105773808733e-10 6.30063548915984 18.5684122239549 0.339320099810767 0.734499312979479 FAM86JP other 1.02374397194826e-05 1 2.58718897522909e-06 6.46366665180676 0.339320099810767 0.000366745256330735 7.4974276331887 10.0326362795402 0.747303841611237 0.455203058418933 -76.3458730695564 22.1648649743582 -3.44445468798833 0.00061633582608944 KYAT1 other 1 1 1 0.747303841611237 -3.44445468798833 0.000925347064055962 -3.05376304023848 1.29438270774595 -2.3592427664275 0.0186640480790135 -15.7753094216858 4.71255333730739 -3.3475078779054 0.000871693652910369 SIGLEC17P other 1 1 1 -2.3592427664275 -3.3475078779054 0.570933120088469 -41.0284069694907 43.6566198586339 -0.939798067334263 0.347735204079127 12.4237471575906 103.906866465844 0.119566180563 0.904870631039297 OBP2B other 1 1 1 -0.939798067334263 0.119566180563 4.65208104234656e-19 54.968934657964 6.18343913175475 8.88970255657142 8.91567584397285e-18 -28.3343409156679 19.0574936595769 -1.4867821247538 0.137649579358342 TRMT61B other 5.38664463893308e-15 1 1.19487887660924e-13 8.88970255657142 -1.4867821247538 1.50689792343687e-31 727.048826411074 62.8359379308251 11.5705892257305 7.63254115654023e-28 -513.952957513511 233.30490409753 -2.20292393553228 0.0280170913118967 INSR other 2.09187569731506e-27 1 1.11114534156913e-23 11.5705892257305 -2.20292393553228 3.88049330582569e-22 247.944717419758 23.8384341806555 10.4010488080195 3.44151994454083e-23 21.3352423869234 98.4782988392208 0.216649176909077 0.828564809745288 MFN1 other 4.7927972820253e-18 1 4.86837411354746e-19 10.4010488080195 0.216649176909077 0.344865676120573 -18.6950269992967 13.9251326764211 -1.34253851892933 0.179979346862646 4.08397186712962 43.0279179674132 0.0949144662361442 0.924417588366267 GIMAP8 other 1 1 1 -1.34253851892933 0.0949144662361442 3.92655189743838e-05 21.126083173847 5.34994004013748 3.94884484972735 8.88901498008961e-05 44.8960381889581 12.9518859372124 3.46637072057329 0.000569372662218595 NRTN other 0.225109220280142 1 0.737610463047836 3.94884484972735 3.46637072057329 0.00676549264825676 23.9483568756402 8.57398502330887 2.79314190665545 0.00540789354972611 -55.1425537396975 35.4197533684319 -1.55683053933526 0.120105384799748 KCNMB3 other 1 1 1 2.79314190665545 -1.55683053933526 0.0782372048252277 30.4573472468972 18.7403528305949 1.62522805852265 0.104693142162834 95.1829116349502 46.9041130418562 2.02930842227016 0.0429132246270779 FUT3 other 1 1 1 1.62522805852265 2.02930842227016 1.7136464813172e-13 378.837786566657 70.8554425654819 5.3466293180873 1.32010645530166e-07 -804.76623875723 218.933826720254 -3.67584238038068 0.000260522165845532 ATP6V0E2 other 1.67131941322867e-09 1 0.00133805990309377 5.3466293180873 -3.67584238038068 0.0216356839064523 -11.8429006132894 13.5353466681004 -0.874961011615631 0.381981248940251 -127.052681328532 46.3303166817695 -2.74232274735403 0.00630158884216876 PRKCE other 1 1 1 -0.874961011615631 -2.74232274735403 1.16441582015125e-46 335.660574738514 20.8631148833536 16.0887085468878 6.9987815443511e-48 124.768481152446 63.6365526759815 1.96064173664042 0.0504335297806467 JAGN1 other 1.74569219757075e-42 1 1.0699737225004e-43 16.0887085468878 1.96064173664042 2.19986076352154e-42 670.252124110196 46.0718162835076 14.5479856922881 1.10295894138478e-40 -313.573383307705 138.894540973977 -2.25763648527018 0.0243676291483837 TADA3 essential 3.25469399963012e-38 1 1.66910776599758e-36 14.5479856922881 -2.25763648527018 0.0013676931263258 92.9774813000578 26.0830016158154 3.56467720508368 0.000396360822913921 117.159172285807 89.9244444535171 1.30286234180037 0.193172985024691 SOCS5 other 1 1 1 3.56467720508368 1.30286234180037 0.00968176066228911 54.7251786850556 38.2145749153542 1.43204991305733 0.152704904484634 -176.371233583198 85.6921042157475 -2.05819702056968 0.0400478775942503 C9orf16 other 1 1 1 1.43204991305733 -2.05819702056968 8.3189559565352e-12 18.1413470260058 7.96793935274393 2.27679280964387 0.0231839854593375 -83.670845913943 15.4649037275822 -5.41036965944465 9.41936829325699e-08 MORN4 other 7.57357750282964e-08 0.00124778371780775 1 2.27679280964387 -5.41036965944465 3.06050293394726e-18 142.185269246693 15.5984253352678 9.11536044123726 1.75697392366365e-18 -116.96072001966 97.8672901213927 -1.19509511170263 0.232600989851634 ZNF672 other 3.47458898091032e-14 1 2.37525304740089e-14 9.11536044123726 -1.19509511170263 2.46189097417375e-08 95.0829633902283 17.0289426097164 5.58360936256697 3.82401989520662e-08 -183.796226638706 106.830963480937 -1.72043966140493 0.0859555816131382 ZNF692 other 0.00018604510091831 1 0.000399227677059571 5.58360936256697 -1.72043966140493 3.08712196922659e-11 32.4364093690288 5.36789342824532 6.04267014660754 2.82347778773711e-09 -18.04874650234 12.077187798673 -1.49444943667459 0.135641212133678 NAIF1 other 2.73241165496246e-07 1 3.08549652643911e-05 6.04267014660754 -1.49444943667459 0.000107405488189825 -2.55423477409631 5.76044515054473 -0.443409269135176 0.657646999952427 -75.9892653803814 17.7500368892952 -4.28107647630915 2.20047385928758e-05 RBKS other 0.580956285618766 0.260074005429199 1 -0.443409269135176 -4.28107647630915 0.0260113251459377 -8.48464351687717 4.33048477562326 -1.9592826107225 0.0506084920662866 -28.6647603231767 12.1902031977166 -2.35145877868106 0.0190686169742922 GRIK1 other 1 1 1 -1.9592826107225 -2.35145877868106 0.260143454295285 -9.27503492167929 5.95188706058702 -1.55833516786599 0.119741842514679 -17.1085395434272 16.4475125015598 -1.04019009207652 0.298718824041937 MUC7 other 1 1 1 -1.55833516786599 -1.04019009207652 0.747511936793873 0.450687083570575 81.3930651485282 0.00553716809593236 0.995584054178897 -160.014791035187 224.922523385156 -0.711421820398034 0.477131219265958 OPRPN other 1 1 1 0.00553716809593236 -0.711421820398034 0.838688400477005 -714.131019554923 1732.88315417339 -0.412105696702657 0.680426406748838 -2611.54823496508 4788.79612701211 -0.545345461719314 0.585742376279334 SMR3B other 1 1 1 -0.412105696702657 -0.545345461719314 6.84418208220556e-52 72.7572776261488 7.05850555625927 10.30774532176 8.1301098618295e-23 -111.233676746432 16.0570559693989 -6.92740169545515 1.25650384706076e-11 TMEM126A other 1.03860463097469e-47 1.82255883016163e-07 1.1465080927152e-18 10.30774532176 -6.92740169545515 7.77244347934535e-55 132.415225829405 11.5487941699736 11.4657187478221 2.55087521328515e-27 -163.888968903347 26.2717983131558 -6.23820900837526 9.10605532325479e-10 TMEM126B other 1.18483128399141e-50 1.27694213798002e-05 3.70259537208339e-23 11.4657187478221 -6.23820900837526 4.39652761357697e-28 75.7458208968639 69.268516555921 1.09351007734825 0.274652994038734 -1555.94447516647 144.382275330373 -10.7765615385004 1.11344332336039e-24 TRIM8 other 5.90717450160202e-24 1.73274049981344e-20 1 1.09351007734825 -10.7765615385004 7.6811983841095e-06 71.971424821781 55.3700517284584 1.29982585486352 0.194279365499844 -472.615631242493 146.278370005594 -3.23093312582317 0.00131788714453146 NETO2 other 0.0471702392768165 1 1 1.29982585486352 -3.23093312582317 0.398920703185657 497.770618477358 462.746418248805 1.07568767438784 0.282549111891063 1473.0343333436 1286.27392100464 1.14519489922729 0.252637606282603 CSN3 other 1 1 1 1.07568767438784 1.14519489922729 9.41085481425078e-09 104.469824183339 32.5987251359464 3.20472115850139 0.0014333226810045 -272.857648294106 76.4217602215682 -3.57041826180154 0.000388826619545646 CDC42BPG other 7.29153031008151e-05 1 1 3.20472115850139 -3.57041826180154 0.00226629834073605 139.307132520928 42.4156393192496 3.28433414553546 0.00108975722906788 -165.039202575878 236.045152868098 -0.699184882936792 0.484743215254047 SCAND1 other 1 1 1 3.28433414553546 -0.699184882936792 0.000342170326281628 183.147957999864 232.795206912722 0.78673423060866 0.431783227232855 -2501.59489850892 709.715414897911 -3.5247859155895 0.000459873842852855 JUNB other 1 1 1 0.78673423060866 -3.5247859155895 0.223039650052259 45.6127736140047 41.2917328732415 1.10464663117985 0.269802877384564 -99.4008414729836 99.2362707912802 -1.00165837229061 0.316955591886785 TMEM37 other 1 1 1 1.10464663117985 -1.00165837229061 0.266873298540553 -0.529216089710069 2.92754813978015 -0.180771097328501 0.85662108902347 13.1662684432959 9.05529059447952 1.45398629739421 0.146582558478348 UGT2B7 other 1 1 1 -0.180771097328501 1.45398629739421 3.25124108659708e-06 -51.9177636892423 93.7529582055094 -0.553772005523676 0.57996076728852 -1185.29462020452 241.261488814546 -4.91290435961637 1.18665999304897e-06 LRG1 other 0.0207039032394502 0.0150183688720278 1 -0.553772005523676 -4.91290435961637 8.04740068746972e-17 39.6196785407035 13.083233504795 3.02827879103303 0.0025927891106108 -183.183542713526 34.2882330921209 -5.34246084426028 1.42273924487425e-07 SHCBP1 other 8.79258999112942e-13 0.00187147120270759 1 3.02827879103303 -5.34246084426028 0.238579746223248 51.9952693819237 33.1943357963912 1.56638981122726 0.117848647607213 123.628633113063 121.097964121048 1.02089770055494 0.307764321880408 SOSTDC1 other 1 1 1 1.56638981122726 1.02089770055494 0.563921627437277 -4.71498203396506 13.7222359494768 -0.343601585873098 0.731279424322017 -43.0110799135134 40.6227755099579 -1.05879225074048 0.290166905757394 NPTX1 other 1 1 1 -0.343601585873098 -1.05879225074048 2.68711378362833e-17 85.4639347407985 29.3792203365355 2.90899260640069 0.00377556306849095 -289.69928868625 49.8011149646639 -5.81712455417524 1.02729444036741e-08 FAM98B essential 2.97839691777364e-13 0.000140400331165015 1 2.90899260640069 -5.81712455417524 6.40423725984041e-17 51.0291137844374 6.55843262647899 7.78068735179389 3.83144054940108e-14 -54.7474192832046 24.2571316921809 -2.25696178665888 0.0244191676193412 ZNF439 other 7.01520149442919e-13 1 4.81956906709162e-10 7.78068735179389 -2.25696178665888 3.34155577720709e-16 72.1133959642656 9.81047738954394 7.35065105405823 7.57361449203052e-13 -95.2437488421465 35.9464645226812 -2.64959990104313 0.00830069136289042 ZNF440 other 3.58548934894321e-12 1 9.22769189708998e-09 7.35065105405823 -2.64959990104313 6.21658732767149e-11 360.302791110396 80.4746878182911 4.47721887314365 9.22469733822032e-06 -1110.16955540534 243.633010333238 -4.55672880241832 6.42509757889718e-06 GAA other 5.41962083226401e-07 0.0784632916334924 0.0833912639375116 4.47721887314365 -4.55672880241832 1.92030787455396e-25 936.115069933682 108.463969210161 8.63065473954634 6.85149202952802e-17 -1695.48169793074 306.579103789658 -5.53032374670257 4.98572614131871e-08 CANT1 other 2.49736039085742e-21 0.000666442013310072 9.06178335825375e-13 8.63065473954634 -5.53032374670257 0.103242766470493 62.701845521531 39.2011912356444 1.59948826923704 0.110292735979818 -117.366875980277 117.35510864614 -1.00010027117074 0.31770662413624 KCNK3 other 1 1 1 1.59948826923704 -1.00010027117074 1.10488476136687e-17 140.500023072175 32.0925764389679 4.3779602220274 1.43560603563244e-05 -347.893723305211 62.3371509808009 -5.58084092441693 3.77096267385227e-08 ZDHHC16 other 1.23669751339794e-13 0.000506214029337929 0.127725868990218 4.3779602220274 -5.58084092441693 0.0818381670553911 -13.3821134289186 29.7783701288549 -0.449390392120604 0.653328392068036 139.820108875892 71.9715100801915 1.94271467585025 0.0525643554398861 CHST11 other 1 1 1 -0.449390392120604 1.94271467585025 6.87457738863205e-20 72.170551650098 13.6897114322957 5.27188261104168 1.94697455441509e-07 -143.536511124352 26.5911217836164 -5.39791108823358 1.00617008657685e-07 EXOSC1 essential 8.12437555788535e-16 0.00133166610958446 0.00195632003227628 5.27188261104168 -5.39791108823358 7.54316090631099e-10 322.300518529958 52.3164031324012 6.16060163223162 1.40570102404608e-09 31.8903865308517 101.620246259724 0.313819221116087 0.753777984018851 PGAM1 essential 6.21556458680026e-06 1 1.55498647279978e-05 6.16060163223162 0.313819221116087 9.03214958587455e-23 232.284450569863 21.9758814660382 10.5699719453274 8.94708985323543e-24 103.520701590546 187.973900351342 0.550718484837819 0.5820645550375 CHD7 other 1.12847676925917e-18 1 1.27164988084035e-19 10.5699719453274 0.550718484837819 6.94813320798082e-07 36.8598495036683 10.925307259981 3.37380438156503 0.000794382679637909 -29.1537060051608 23.1855098442889 -1.25741060692448 0.209146514719649 ESCO2 other 0.0047094446883694 1 1 3.37380438156503 -1.25741060692448 4.76510849193959e-17 5644.00130003875 1402.09605935984 4.02540272641208 6.49487409005549e-05 -26879.2835337165 4113.09085270521 -6.53505708876764 1.46427233062822e-10 KRT19 other 5.24400189537952e-13 2.08658807114521e-06 0.546138572743275 4.02540272641208 -6.53505708876764 0.375035734216903 -1.48898091244251 2.18778235122136 -0.680589141607831 0.49642159290447 -6.19986423860418 4.45945404410794 -1.39027427512024 0.165015195413413 LURAP1 other 1 1 1 -0.680589141607831 -1.39027427512024 0.100186094447561 29.4389247324224 19.6871685682295 1.49533563602081 0.135431159016025 -118.113849114347 90.1671543000984 -1.30994318309343 0.190791229407492 TPPP other 1 1 1 1.49533563602081 -1.30994318309343 0.000487549669630774 -9.31680623834687 58.4859625063106 -0.159299870243934 0.873491639051647 -467.686118904209 129.344467615496 -3.61581850021219 0.000327187085830835 KCND3 other 1 1 1 -0.159299870243934 -3.61581850021219 0.464062670019676 -72.4064934665716 197.159019597204 -0.367249206323394 0.713575435758833 -721.821313582932 582.144063377367 -1.23993588355984 0.215531730950785 KRT13 other 1 1 1 -0.367249206323394 -1.23993588355984 0.235126904582786 -8.89768560451537 6.3295814358616 -1.40573048860761 0.160391219153039 -21.72843952887 14.4128077933237 -1.5075785260201 0.132259373811862 PDE7B other 1 1 1 -1.40573048860761 -1.5075785260201 6.16643924658272e-23 130.898493548933 12.5007020278146 10.4712913928896 1.94329483751837e-23 -17.5271729002815 57.0922029596655 -0.306997663282745 0.758966418064673 MRPL36 other 7.72038193672156e-19 1 2.7550090911498e-19 10.4712913928896 -0.306997663282745 5.17579375860446e-19 113.777848414046 12.4386856530511 9.14709572921292 1.22022265416567e-18 -65.3448718776131 55.4581379987815 -1.17827381581128 0.239211276367826 ZNF581 other 5.98632306120192e-15 1 1.65291360733282e-14 9.14709572921292 -1.17827381581128 7.92475357026718e-19 648.852363278852 348.086942101661 1.86405258226938 0.0628537520248681 -4339.03855616521 718.048149547097 -6.04282395115428 2.8147712945897e-09 NAT1 other 9.12139135937752e-15 3.90324335420754e-05 1 1.86405258226938 -6.04282395115428 0.85821256866641 -10.1034245144438 18.4101104604685 -0.548797604237007 0.583371186895924 -17.0020629618395 79.7040766020661 -0.213314847705027 0.831161902881997 KRT20 other 1 1 1 -0.548797604237007 -0.213314847705027 5.08902854764603e-07 4.44543857000119 6.34694008089485 0.700406575978646 0.48397452810764 -70.3154947586204 14.2067019302606 -4.94945942441763 9.9557692141501e-07 KSR2 other 0.00348140442944465 0.0126428313250492 1 0.700406575978646 -4.94945942441763 4.23504852571529e-08 57.0546399987525 11.2288429519158 5.08107916755733 5.20347392476359e-07 -105.056426331455 48.9953830740109 -2.14421073456574 0.032468471532089 ZNF524 other 0.000314706455945903 1 0.00509784340409089 5.08107916755733 -2.14421073456574 1.6558314544704e-07 24.7154433808184 50.6936681608239 0.487544979037807 0.626068590264437 -573.09473716608 113.405162509484 -5.05351541750273 5.93310886842011e-07 MCC other 0.00117977991131016 0.007612178678183 1 0.487544979037807 -5.05351541750273 1.03148589466793e-16 39.5075606900472 8.87993386741782 4.44908276119128 1.04743133197494e-05 -136.267426800297 21.9793413096266 -6.19979574822901 1.12263712612718e-09 ZBTB26 other 1.12380388224071e-12 1.57079386687715e-05 0.094205973997826 4.44908276119128 -6.19979574822901 0.125112041847723 22.9996124835652 63.1875340372846 0.363989714648366 0.716010303133633 -212.231488478306 128.160865021117 -1.65597734100294 0.0983160840613043 DSEL other 1 1 1 0.363989714648366 -1.65597734100294 2.21457490050691e-60 172.960818791581 9.70442493637765 17.8228818220054 3.17511647675854e-56 -110.939067693837 51.6960191284096 -2.14598859959161 0.0323189221947447 POLR1C essential 3.40446599454927e-56 1 4.89348951398026e-52 17.8228818220054 -2.14598859959161 5.62529264986267e-14 195.61848021895 27.8548912814119 7.02276947494282 6.60703350595003e-12 -467.484999278779 161.133300865256 -2.90123144482532 0.00386942696342625 ASXL1 ts 5.58647813057862e-10 1 7.87492323574185e-08 7.02276947494282 -2.90123144482532 0.014965285467805 1.93927918637538 1.75105961807227 1.10748895489368 0.268574738785357 -21.9008549357179 9.26861507078961 -2.36290478873583 0.0184851450359387 DLK2 other 1 1 1 1.10748895489368 -2.36290478873583 7.44488667673158e-35 223.896949378986 17.8159584027688 12.5672132992963 6.48885114863451e-32 -115.725445307202 66.9213862863176 -1.72927447755012 0.0843378912115682 ZNF562 other 1.06089635143425e-30 1 9.60090415951962e-28 12.5672132992963 -1.72927447755012 1.1753307796237e-51 271.418290475912 16.5544427578978 16.3954954235125 2.60787647284033e-49 -95.2889405430228 88.3599038873424 -1.07841833626839 0.281329480115463 ZNF318 other 1.7825066603773e-47 1 3.99370203050768e-45 16.3954954235125 -1.07841833626839 1.42132436339464e-17 101.963773191619 17.3868515360193 5.86441846474546 7.90526333142728e-09 -347.570864812422 65.3106545096477 -5.32180954887045 1.51476270591518e-07 ZNF561 other 1.58619798954842e-13 0.00198903490913722 8.49341492328547e-05 5.86441846474546 -5.32180954887045 5.66566760767053e-115 620.20145540914 21.5249979140381 28.8130785371486 1.89843164776619e-109 -546.930102426461 171.501184003848 -3.18907479037689 0.00151414420909607 WIPF2 other 8.86280383867902e-111 1 2.96933694027109e-105 28.8130785371486 -3.18907479037689 0.503516403349937 17.6779783342889 23.5884612787283 0.749433298145251 0.45392548481054 -32.9691943124311 56.9049540815477 -0.579373006174199 0.562581384194309 HOPX other 1 1 1 0.749433298145251 -0.579373006174199 0.238038895001495 9.85964460148362 8.90860735554589 1.1067548728978 0.268885512000101 -45.1154886232563 40.4890995401511 -1.11426258266172 0.265655010203149 NLRP5 other 1 1 1 1.1067548728978 -1.11426258266172 0.000522127242092802 116.895278228231 33.7643354193938 3.46209326427576 0.000578701779722671 -20.1497911493954 66.9194665205191 -0.301105077447337 0.763450921110688 LRRC8C other 1 1 1 3.46209326427576 -0.301105077447337 2.53098510049434e-18 660.621187765724 86.9617326873735 7.59668842087876 1.35214702368276e-13 -1334.21987053524 451.368330816551 -2.95594480038412 0.0032535730441947 RSL1D1 essential 2.8805141428726e-14 1 1.67842010049741e-09 7.59668842087876 -2.95594480038412 4.63712614045333e-14 537.112382567432 69.6774554870094 7.70855334502809 6.20203354570824e-14 121.487842676694 137.994652110755 0.880380803302342 0.379046877584528 LRRC8D other 4.61579536020725e-10 1 7.7612247790993e-10 7.70855334502809 0.880380803302342 4.27827336268588e-35 265.829464488127 21.9787792908037 12.0948238740154 5.5815077792208e-30 -51.6743739640867 48.8097496588378 -1.05868959224892 0.29021275731947 PPID other 6.1085187072429e-31 1 8.20314198312081e-26 12.0948238740154 -1.05868959224892 0.0561231696621037 -0.943033339601481 5.53753134831061 -0.170298510344177 0.864839523119304 -24.050857876984 10.6213798518238 -2.26438167286279 0.023948551425731 COL24A1 other 1 1 1 -0.170298510344177 -2.26438167286279 9.7686385475123e-21 109.774058309652 18.8716909448378 5.8168639275899 1.02585196786882e-08 -223.455398277314 41.9096301240854 -5.33183895003871 1.42942782641862e-07 ETFDH other 1.17399498064003e-16 0.00187984053452313 0.000109755902042285 5.8168639275899 -5.33183895003871 0.000147558044273755 55.7031123871933 16.1321844040008 3.45291815368653 0.000597886326360746 -24.0437736750051 30.7607084982104 -0.781639138006328 0.434767980284886 LPAR3 other 0.784271005315009 1 1 3.45291815368653 -0.781639138006328 0.471417382427944 -10.6344007124381 10.0097153909051 -1.06240790043847 0.288523683037265 -37.165296240927 46.7504973178562 -0.794971141980384 0.426978262639132 PTGER4 other 1 1 1 -1.06240790043847 -0.794971141980384 5.04966687565332e-23 286.622156343778 42.0924878949787 6.80934225268184 2.60127639262656e-11 -421.283640106548 92.9363946346335 -4.53303188447072 7.15506668867864e-06 TBCA essential 6.32824252856874e-19 0.0871527910299332 3.04895605979759e-07 6.80934225268184 -4.53303188447072 0.486144181696252 6.17542723288156 6.70150177179399 0.921499007710984 0.357224804986101 -14.857468736111 30.3304414304705 -0.489853363003973 0.624447896821756 MAP6 other 1 1 1 0.921499007710984 -0.489853363003973 0.602837384030484 -54.1803289917961 159.973423770042 -0.338683311983615 0.73498069923505 253.285593151575 318.038685882377 0.796398691086433 0.426152271416366 ECEL1 other 1 1 1 -0.338683311983615 0.796398691086433 9.90864847521209e-16 439.707727061355 58.3728238712243 7.53274722551354 2.19241523905727e-13 -1121.33242694408 344.28641214688 -3.25697555111672 0.00119896130926486 BCL2L1 essential 1.04833500867744e-11 1 2.70916751090307e-09 7.53274722551354 -3.25697555111672 0.567314340696189 -404.50386358547 485.86148837618 -0.832549755975477 0.40546404561891 -1013.34237879628 1092.31806553746 -0.927699001570279 0.353975137233518 FGG other 1 1 1 -0.832549755975477 -0.927699001570279 0.648416016241234 -451.083545252244 578.106085121934 -0.780278147664024 0.435566540079847 -991.812234483581 1299.7031781348 -0.763106724034429 0.44573053877236 FGA other 1 1 1 -0.780278147664024 -0.763106724034429 0.605678211456726 -511.040118935372 546.137076528929 -0.935735991746574 0.349823566318846 -844.571730890459 1233.43933782378 -0.684729037733287 0.493806008149106 FGB other 1 1 1 -0.935735991746574 -0.684729037733287 5.07283647051525e-21 264.242333405455 26.711859129758 9.89232281144666 2.4812617639533e-21 112.254115644202 60.3281836246207 1.86072427346195 0.0633214503263257 PLRG1 other 6.13255200920588e-17 1 3.45168323983544e-17 9.89232281144666 1.86072427346195 7.0881386985435e-30 38.4242279264239 3.75773625242653 10.2253658440269 1.98297017633394e-22 -60.0584652858996 13.7758909959942 -4.35967918905306 1.57978238042917e-05 ZNF584 other 9.68877678703912e-26 0.188515431456612 2.78527990967865e-18 10.2253658440269 -4.35967918905306 0.361151111445208 5.77786377080902 4.27686208101107 1.35095863775039 0.177272370353259 7.54641947809897 8.70139652806605 0.86726532387741 0.386180444221565 NMUR1 other 1 1 1 1.35095863775039 0.86726532387741 1.97896554823472e-18 1381.90340043265 221.6020500002 6.23596848689531 9.04263667237345e-10 -1115.09396908105 366.392021644204 -3.04344500755505 0.00245230190966563 CLSTN1 other 2.25839548364546e-14 1 1.00834441533636e-05 6.23596848689531 -3.04344500755505 2.20425920380722e-23 473.970501053313 108.020773704432 4.38777176647705 1.37582355258886e-05 -1964.41506440096 257.326217601574 -7.63394838936516 1.02857841153178e-13 CXXC5 other 2.77824830047862e-19 1.52754179896585e-09 0.122627153242245 4.38777176647705 -7.63394838936516 1.51587278456698e-22 179.478047684429 17.3884225244823 10.3216980972098 7.69809063828131e-23 -6.31351977187373 75.514985879337 -0.0836061835721178 0.93340184947506 ZNF274 other 1.88604891855824e-18 1 1.0857387036232e-18 10.3216980972098 -0.0836061835721178 0.0089469535981735 50.6033598237504 24.8319889692773 2.03782950638219 0.0420556419396385 -41.5424916828589 40.8969777630294 -1.0157839027512 0.3101888901135 PIK3CD other 1 1 1 2.03782950638219 -1.0157839027512 2.61738019782226e-16 121.789123094351 15.1386603322446 8.04490756919527 5.54201943109447e-15 22.1865156095548 24.8517353785872 0.892755184761511 0.372387431774052 SLC25A33 other 2.81865673503479e-12 1 7.08270083293873e-11 8.04490756919527 0.892755184761511 0.648523795153936 -30.791584726702 87.2627128993689 -0.352860731733275 0.724329029162597 -189.440939855285 203.485912210898 -0.930978158620358 0.35227630686661 ENC1 other 1 1 1 -0.352860731733275 -0.930978158620358 0.000759825069164275 74.6168641417476 45.5225763502948 1.63911777680536 0.101772243733106 -164.452327118644 74.8143188208351 -2.19813973729378 0.0283635543776951 SPSB1 other 1 1 1 1.63911777680536 -2.19813973729378 0.394885911936242 9.29849466925682 6.93386898167387 1.34102543527036 0.180524731537237 5.6312990912669 21.0949106738177 0.26695060141953 0.789617924329719 P2RY6 other 1 1 1 1.34102543527036 0.26695060141953 3.3250181946635e-45 737.456064277487 48.0216064757635 15.3567553940471 3.79350362998151e-44 -297.716825431931 218.591702143928 -1.36197679286062 0.173796051047335 BPTF other 4.96890719010514e-41 1 5.76953967083888e-40 15.3567553940471 -1.36197679286062 4.22052794669780e-12 62.3134717827676 8.66431974068283 7.19196355256583 2.12415067602682e-12 127.918110719836 43.4907765323215 2.94126987189501 0.00340786245108829 ZIK1 other 3.89090471406071e-08 1 2.56448711116717e-08 7.19196355256583 2.94126987189501 0.00211607862481502 -8.11835602074285 23.8935465045095 -0.339771913692705 0.734160657800683 -124.758040198957 38.7801799585869 -3.21705676281505 0.00137289312067495 PLEKHG5 other 1 1 1 -0.339771913692705 -3.21705676281505 7.78656103517804e-11 376.982971422503 61.9067768016068 6.08952671903148 2.14408806617663e-09 -225.159120376449 193.276315669831 -1.16495970857124 0.244546822852976 ATF7IP other 6.75639901022399e-07 1 2.35356547024209e-05 6.08952671903148 -1.16495970857124 7.41098724096195e-22 83.0130393732937 8.09524046333543 10.2545489228235 1.61338260028217e-22 134.875977920283 49.1775262201882 2.74263445697507 0.00631395313925145 RGS19 other 9.10810331914224e-18 1 2.26744790643657e-18 10.2545489228235 2.74263445697507 1.41700161761634e-14 179.57347725127 22.186649665427 8.09376268878918 4.44828012310606e-15 -80.3902913625036 134.78099268346 -0.59645124851769 0.551144293509336 TCEA2 other 1.43868174236587e-10 1 5.69468821360038e-11 8.09376268878918 -0.59645124851769 2.01538427080421e-07 100.499271121269 17.9074040082944 5.61216305136801 3.20281025319438e-08 68.68398198091 46.8755748980556 1.46524031183155 0.14343950798703 ANO5 other 0.00142507821788566 1 0.000335494374022111 5.61216305136801 1.46524031183155 2.18107553412403e-14 136.829935313941 21.9123670621386 6.24441599239015 8.60902843175855e-10 -142.231827466461 51.7690606431257 -2.74742917293686 0.00620675337289566 HDAC3 essential 2.19830603084361e-10 1 9.60767572984254e-06 6.24441599239015 -2.74742917293686 4.98768983245808e-06 80.5968821652213 29.821881518508 2.7026088919038 0.00709792730570259 -151.467415603287 57.715174843609 -2.62439498821097 0.00892786961990486 GPHN other 0.0311381476240358 1 1 2.7026088919038 -2.62439498821097 0.387002272453142 5.58901754803296 8.0036425239438 0.698309242487128 0.485280575369967 -10.0727470180614 18.0119090003477 -0.559227065707858 0.576235649241899 VAT1L other 1 1 1 0.698309242487128 -0.559227065707858 5.37095255535564e-05 70.9039485266776 19.4978973789117 3.6364920354625 0.000302749966198163 -10.4667268198306 31.8557646648929 -0.328566177266045 0.742610520266087 TMEM51 other 0.302277209815415 1 1 3.6364920354625 -0.328566177266045 8.70813601615651e-18 163.584618106455 25.598959515237 6.3902838710724 3.56602299714787e-10 -112.347707733899 42.3150934076982 -2.65502681635249 0.00816298078212935 CAMTA1 other 9.78010755974538e-14 1 4.04030405576853e-06 6.3902838710724 -2.65502681635249 0.412283231591664 1.66025740585152 2.35136106650276 0.70608356560095 0.480443526166072 11.398941169299 10.1716253239361 1.12066074066598 0.262935093132124 LRRC34 other 1 1 1 0.70608356560095 1.12066074066598 0.518447841789599 7.40679511729637 26.1359160827905 0.28339527468002 0.776981269946838 -61.71047810047 63.2612227654306 -0.975486647314569 0.329750904794037 PAH other 1 1 1 0.28339527468002 -0.975486647314569 2.75125889580506e-19 35.5909477082637 6.43806885361065 5.5282024031637 5.05113427744984e-08 -50.139120779007 11.3773419184208 -4.40692748258079 1.26604674766783e-05 SPATA5L1 essential 3.20741762072954e-15 0.151925609720139 0.000524509783370392 5.5282024031637 -4.40692748258079 9.83198944367356e-05 -69.1656663493228 58.3335626249327 -1.18569247679997 0.236267179215435 -434.076655171981 102.330712968516 -4.2419000374358 2.60953878219376e-05 GATM other 0.534663585946968 0.306568616132123 1 -1.18569247679997 -4.2419000374358 0.312277181003361 15.9766394454695 11.203996987448 1.42597677091206 0.154473931691453 1.40911669903448 22.2330829538783 0.0633792759176783 0.949488797737412 SYCE1 other 1 1 1 1.42597677091206 0.0633792759176783 0.00948544262125681 -0.8122104104457 0.989748825405994 -0.820622757609773 0.412219961816741 -18.078594263479 5.91596759337092 -3.05589812285935 0.00235375917548651 RASGRP4 other 1 1 1 -0.820622757609773 -3.05589812285935 6.99922027470853e-07 5.07709852431468 1.22063024829327 4.15940743023014 3.71336638463132e-05 -5.45532807562198 2.73443824808323 -1.99504526366468 0.0465418828726818 SLFNL1 other 0.00473987197003262 1 0.319238108086754 4.15940743023014 -1.99504526366468 9.70480832694247e-19 411.727059527977 150.478319479714 2.73612212677244 0.00641989579906324 -2342.10006412635 328.591533399985 -7.12769449624065 3.26018216696787e-12 BCL2 ts 1.11498542868242e-14 4.76312614594006e-08 1 2.73612212677244 -7.12769449624065 9.14059229735552e-52 301.773195277124 18.7631694353461 16.0832740074629 8.51385589599649e-48 -97.8587515432867 69.0378006342981 -1.41746623797674 0.156926602931517 RHNO1 other 1.38671925743181e-47 1 1.30117259658514e-43 16.0832740074629 -1.41746623797674 3.06170082121227e-18 406.254602531283 46.4773833558302 8.74090951766805 2.95066097789895e-17 -43.8166843165222 104.117962746467 -0.42083693496019 0.674042214133047 CTPS1 essential 3.47564277224017e-14 1 3.92378896841003e-13 8.74090951766805 -0.42083693496019 0.456383867321017 8.98996684541544 19.925095221585 0.45118814968957 0.652039547017787 -35.3758917487734 39.9799596489639 -0.884840606628532 0.376646129522577 KNDC1 other 1 1 1 0.45118814968957 -0.884840606628532 1.13034377796397e-15 39.7892458339093 4.77829716064595 8.3270764659874 6.77529811832547e-16 -49.6536125387028 35.931819930124 -1.38188415268871 0.167575503780109 METTL18 other 1.19296482326317e-11 1 8.80178978551661e-12 8.3270764659874 -1.38188415268871 1.15310283090553e-08 -5.20139553719498 4.02297980311227 -1.29292111612667 0.19659743370395 -47.545565660572 7.88436805713668 -6.03035846576636 3.05615668597106e-09 CFAP46 other 8.88350420929621e-05 4.23338824140712e-05 1 -1.29292111612667 -6.03035846576636 0.000618139755578617 -299.698718042315 123.427148306989 -2.42814261005935 0.0155075367291225 -912.103150048588 246.360839993229 -3.70230573200537 0.000235980395747725 COL8A2 other 1 1 1 -2.42814261005935 -3.70230573200537 3.78677615747048e-12 103.3380307714 28.861500534228 3.58048018497333 0.000374314401737947 -262.126513391228 57.4093246338083 -4.56592226198846 6.1815522066794e-06 PWWP2B other 3.49670910380824e-08 0.0755571126222423 1 3.58048018497333 -4.56592226198846 9.23850894423324e-06 -2.4267263503401 2.48816170301653 -0.975308938883695 0.32984454666686 -59.4484101821041 12.2155673935087 -4.86661063436928 1.49306354936709e-06 ZNF540 other 0.0563733815777112 0.0188096145949266 1 -0.975308938883695 -4.86661063436928 0.951908023810049 0.107647780887928 9.08298553592412 0.011851585633619 0.990548361179356 -3.90641977514405 14.7005644743842 -0.265732637814759 0.790545615366627 ANGPTL7 other 1 1 1 0.011851585633619 -0.265732637814759 6.75642989544959e-21 60.4803768050712 6.97042839612642 8.67670871401263 5.01568396807153e-17 -81.5004898543488 27.8928686051575 -2.92191136767048 0.0036273145391052 FBXL14 other 8.15230831184948e-17 1 6.64879066807562e-13 8.67670871401263 -2.92191136767048 6.18954635266496e-20 181.763764696364 43.3158389010761 4.19624251330958 3.1682267015726e-05 -391.498135357126 69.8746191552417 -5.60286610632292 3.3499760171008e-08 EXOSC10 essential 7.32037647129684e-16 0.000450169777178006 0.274241703288124 4.19624251330958 -5.60286610632292 1.61146427223011e-29 62.6528310803914 5.33426135500924 11.7453620868344 1.64626598106025e-28 -23.408910652518 25.7723076542678 -0.908297035971537 0.364128746161651 ZNF570 other 2.19416975306852e-25 1 2.40404221214229e-24 11.7453620868344 -0.908297035971537 0.167410907187776 9.11917246232458 5.45851009544063 1.67063398306099 0.0953968742110613 -8.17868734856201 20.8647302492884 -0.391986249083711 0.695229280968411 NINJ2 other 1 1 1 1.67063398306099 -0.391986249083711 0.0742263570936593 44.5050268620906 40.933975874788 1.08723928988052 0.277417922257332 -136.051098155964 94.341691526138 -1.44211001472525 0.149853205523113 MLLT3 other 1 1 1 1.08723928988052 -1.44211001472525 3.08684446473872e-14 16.7274453337461 2.07858464475262 8.04751703327284 5.31820410467408e-15 6.63667116230738 7.42806237637744 0.89345926649905 0.372005631716591 FAM90A1 other 3.09579631368646e-10 1 6.79772848659441e-11 8.04751703327284 0.89345926649905 4.17382891577947e-19 777.874408210265 81.3759498631179 9.55902093331905 4.11399698991033e-20 676.436570601456 243.445822052205 2.7785918234259 0.00564885380130317 RRM2 essential 4.84164154230419e-15 1 5.66373965600955e-16 9.55902093331905 2.7785918234259 7.09865370554565e-13 76.7407826885419 16.5638307428018 4.63303349811706 4.51426078486741e-06 -253.224778448042 51.0211568668099 -4.9631328256449 9.29336218752473e-07 TRAPPC12 other 6.7415914241567e-09 0.011823015374969 0.0416530842619716 4.63303349811706 -4.9631328256449 2.14913558565292e-13 1485.33256116304 190.382861989262 7.80181863873236 3.39932237834572e-14 43.3977422146026 1411.58381257462 0.0307440067164334 0.975485559957711 RPS21 essential 2.08681065366899e-09 1 4.28110660328861e-10 7.80181863873236 0.0307440067164334 0.211838938912296 -1.58308271826681 12.3590280497969 -0.12809119874866 0.898124051603695 74.2385286549578 44.1906808067427 1.67995892572061 0.0935383785715817 C3AR1 other 1 1 1 -0.12809119874866 1.67995892572061 1.7445912716284e-45 98.703709790122 9.93926287341302 9.93068711907691 1.93151728480684e-21 -125.238246024929 18.2278976470947 -6.87069065504053 1.7852840711204e-11 MRM3 other 2.6088617875931e-41 2.58259193728277e-07 2.69021727427897e-17 9.93068711907691 -6.87069065504053 6.72747890271915e-14 35.8498097363682 67.4730281251193 0.531320599245817 0.595419650802195 -1032.26186560369 140.951303245154 -7.32353544690748 9.05849433346161e-13 PTEN ts 6.66356785314332e-10 1.33150808207552e-08 1 0.531320599245817 -7.32353544690748 3.83767495932083e-12 631.791070228258 89.3851394932337 7.06818911745485 4.8342101860894e-12 -188.21066988981 273.471164469257 -0.688228575232357 0.491602216350586 RPS7 essential 3.54294152244499e-08 1 5.78413248765597e-08 7.06818911745485 -0.688228575232357 0.0226728845965519 -13.626567926448 5.49484188727143 -2.47988353550506 0.0134430246973284 -41.096381277436 22.7300122455875 -1.80802283929318 0.0711530575165774 PRND other 1 1 1 -2.47988353550506 -1.80802283929318 2.31883008380919e-29 104.90525778625 8.70167257301062 12.0557578909171 7.90328050405843e-30 18.9615721634126 26.6225073302206 0.712238405204167 0.47662250508024 RNASEH1 other 3.15407267999726e-25 1 1.1608338404361e-25 12.0557578909171 0.712238405204167 0.116643635276261 151.327390477401 84.8183358705774 1.78413533965472 0.0749568912237418 520.648342046896 350.860289074838 1.483919264331 0.138407365225109 PRNP other 1 1 1 1.78413533965472 1.483919264331 0.123034215072917 3.19119045621953 5.83346824251675 0.547048569316072 0.58457959651056 20.1101842425881 10.0601948962882 1.99898555146362 0.0461288993986617 FRMD5 other 1 1 1 0.547048569316072 1.99898555146362 0.858819339754747 15.6223429801114 29.8119829315732 0.524028979084317 0.600476627233944 2.17916744770141 67.090140828846 0.0324811875601916 0.974100500496471 AQP4 other 1 1 1 0.524028979084317 0.0324811875601916 1.11691615577872e-05 66.7196962031014 13.9792018809467 4.77278293648787 2.33499718233888e-06 29.3689887371709 51.5504708640442 0.56971329737466 0.569106060576567 CYP4F11 other 0.0676516115555172 1 0.0219886684660852 4.77278293648787 0.56971329737466 0.0459390033888292 83.1218265730378 50.9237872215574 1.6322789625091 0.103203691295764 -150.192808845571 112.447727038348 -1.33566780584503 0.182220549619806 TLN2 other 1 1 1 1.6322789625091 -1.33566780584503 7.57774479085192e-05 -1.15726053217144 4.02392289952743 -0.287595105837478 0.773770178087433 -38.3285075220656 9.42201496477803 -4.06797353489118 5.47102084879032e-05 LGALS9C other 0.418746177142477 0.629519801058122 1 -0.287595105837478 -4.06797353489118 1.42973940705108e-43 215.575033892086 19.0878392653062 11.2938416389492 1.1232967081714e-26 -242.521814822637 49.1350589075104 -4.93582017026069 1.06785948549816e-06 TVP23B other 2.12459275887791e-39 0.0135425939950877 1.62451169935748e-22 11.2938416389492 -4.93582017026069 1.27722913687611e-14 768.957386264753 95.7372674665056 8.0319546046557 6.4839010332334e-15 -865.446787218488 747.539125640547 -1.1577277463262 0.247507661212829 ZNF217 other 1.29932520094407e-10 1 8.2786448392324e-11 8.0319546046557 -1.1577277463262 3.42799726345994e-06 61.9720224438606 12.1253242189874 5.11095796900977 5.35847536624318e-07 45.875825229344 48.2895894452067 0.9500148118136 0.34277952306487 SRGAP2C other 0.0217643546257072 1 0.00524326814586895 5.11095796900977 0.9500148118136 0.226614016299872 -42.7062230441667 34.7989271420834 -1.2272281518852 0.220268645917338 -112.63242938611 75.002583874572 -1.50171398860694 0.133752263290158 SCG2 other 1 1 1 -1.2272281518852 -1.50171398860694 2.43502160348421e-66 72.0334453280311 11.0985923871322 6.49032262970096 1.99114884904232e-10 -301.326452034466 21.4362191974259 -14.0568842508687 2.64880642415055e-38 ATPAF2 other 3.76137787090206e-62 4.15200406985598e-34 2.27150260698748e-06 6.49032262970096 -14.0568842508687 0.00614534429824906 -68.7963553059035 35.0093066797376 -1.9650876247064 0.0499125173773828 -377.351187071 127.20381659613 -2.96650837347974 0.00314437480388697 CYP4F22 other 1 1 1 -1.9650876247064 -2.96650837347974 6.92803804907775e-28 202.678962431241 19.3063806046156 10.4980299820043 1.36650510549225e-23 -94.8412125168247 46.1385533710194 -2.05557403922414 0.0403029884270983 PPIH essential 9.284956593374e-24 1 1.93920739520405e-19 10.4980299820043 -2.05557403922414 5.74354381574685e-49 -12.8430049637686 12.7109975273341 -1.01038529321956 0.312777944785401 -335.773599542247 22.3056732508295 -15.0532824437281 8.32597251951137e-43 DRC3 other 8.66068971976468e-45 1.30542923133419e-38 1 -1.01038529321956 -15.0532824437281 2.21148597502179e-17 22.247906995199 4.06876713717309 5.46797254429665 6.94201362051478e-08 -35.6296316247833 8.53473861847759 -4.17465996529123 3.47370188098615e-05 ZNF57 other 2.45408598648168e-13 0.404512584040837 0.000715791024411279 5.46797254429665 -4.17465996529123 6.23678320850908e-13 11.3162986897369 2.10237865941926 5.38261679885143 1.09085280629022e-07 -34.2225595026691 8.56644313614551 -3.99495554441603 7.35624911338673e-05 C20orf196 other 5.93492290121724e-09 0.837582524050213 0.00111103358320658 5.38261679885143 -3.99495554441603 6.72883677929357e-07 153.149468656261 59.8488413132337 2.55893790582703 0.0107758580224717 -543.61942831408 151.015649095705 -3.5997555986371 0.000348418077953369 JMJD1C other 0.00456282422003897 1 1 2.55893790582703 -3.5997555986371 0.219569206173664 202.220614760511 138.375006237954 1.46139552407872 0.144483233599702 -130.14291300796 328.260785473107 -0.396461955759934 0.691919450383274 SYNPO other 1 1 1 1.46139552407872 -0.396461955759934 0.0890528043434559 7.75557321959716 3.51854309580066 2.20420015001475 0.0279282595016058 7.14363911558636 7.33787566044326 0.973529594415999 0.330722838457372 ZNF556 other 1 1 1 2.20420015001475 0.973529594415999 0.634971705362849 11.2388413444743 14.9601215845483 0.751253342491712 0.452863816455279 40.6180007868032 56.3957682433721 0.720231358699096 0.471728803543609 MAL other 1 1 1 0.751253342491712 0.720231358699096 3.25377620076816e-37 28.7360316698307 4.2285639819286 6.79569513258838 2.83865358208676e-11 -70.1461368419104 8.81861494283055 -7.95432585464439 1.05009971860765e-14 ZNF554 other 4.70105585486983e-33 1.57262933858682e-10 3.32321174854897e-07 6.79569513258838 -7.95432585464439 1.76144996189813e-13 29.0352646791283 11.6827053129755 2.48532030050266 0.0132456360243895 -154.911116147395 25.6788763010712 -6.03262831017776 2.99950004955759e-09 RAB33B other 1.71670913286592e-09 4.156107268667e-05 1 2.48532030050266 -6.03262831017776 3.01718776351992e-12 167.307988381939 37.2884093062843 4.48686311630199 8.82495289037588e-06 -259.547572996852 77.7644904766945 -3.33761041068785 0.000902796513341542 THOP1 other 2.79874336944108e-08 1 0.0799099484223535 4.48686311630199 -3.33761041068785 0.153592426934235 24.9693285504625 13.4623800260795 1.85474845473769 0.0641780451941555 5.656281843714 25.7787046458311 0.21941683732463 0.82640842128429 EPHX4 other 1 1 1 1.85474845473769 0.21941683732463 1.09157585255079e-25 38.8908679613886 308.537043414642 0.126049266340844 0.899741553135248 -5542.96407742713 558.501158168585 -9.92471366684967 2.22743403174098e-21 LAMB2 other 1.42363322689674e-21 3.44494947349061e-17 1 0.126049266340844 -9.92471366684967 7.72717573806806e-37 140.169172952705 37.9961438417141 3.68903680164564 0.000248766021893597 -697.290666333206 68.7790681685466 -10.1381231950462 3.63927465865587e-22 USP19 other 1.11379511088513e-32 5.64014786598487e-18 1 3.68903680164564 -10.1381231950462 2.55062719258166e-189 1132.02425065833 24.3175979997059 46.5516475217667 3.18715507166368e-187 -1078.31046943993 497.711444427094 -2.16653742145944 0.0307253943771219 ORMDL3 other 3.99810812437175e-185 1 4.99554685932565e-183 46.5516475217667 -2.16653742145944 1.93485125661383e-14 25.403861912479 8.51046136945968 2.98501583047452 0.00297120899454611 -116.395505731868 19.623056496669 -5.93156859899098 5.52741910876524e-09 SERF1A other 1.95497370968262e-10 7.61015062894798e-05 1 2.98501583047452 -5.93156859899098 3.47850568024184e-15 184.986847550639 22.0336243774572 8.39566130299926 4.07786996733492e-16 92.599321789496 66.1986395094454 1.39881004316235 0.16244296777627 KLF11 other 3.61347170063522e-11 1 5.317134650408e-12 8.39566130299926 1.39881004316235 0.153555372426788 -210.386367725715 159.375588483732 -1.32006645263111 0.187364967242642 -1024.4403049599 746.377191762128 -1.37255038908851 0.17045466107778 LRRC15 other 1 1 1 -1.32006645263111 -1.37255038908851 4.43018167177979e-11 75.6298621541493 18.4640683742493 4.09605622234512 4.88409796860929e-05 -159.416583141083 42.5072740932144 -3.75033653749469 0.000196758446869164 SMN1 other 3.8888134714883e-07 1 0.415001804392731 4.09605622234512 -3.75033653749469 0.209862820985004 55.5012531880203 34.5064162557761 1.60843284265227 0.108343864862836 -61.8915732569917 134.694649999284 -0.459495408743558 0.646069381188723 EIF2AK3 other 1 1 1 1.60843284265227 -0.459495408743558 4.83834138421189e-30 45.4993685323764 27.0247095468524 1.68362100075469 0.0928505215702621 -493.84533669171 49.3057076251742 -10.0159872046855 1.00684942600082e-21 MOB3A other 6.62175401843239e-26 1.55850222650668e-17 1 1.68362100075469 -10.0159872046855 0.730550476897662 2.95232262347734 23.6016866217513 0.125089476476503 0.900500688834378 -69.9533307477484 93.1591870447326 -0.750901043330903 0.453049284118603 KRCC1 other 1 1 1 0.125089476476503 -0.750901043330903 2.52946012950855e-35 26.9166096548554 10.8577290034395 2.47902757992291 0.0134876458220393 -207.736195250304 19.5866215276906 -10.6060248806369 6.11570498514511e-24 NME6 other 3.61864566127493e-31 9.50625182890956e-20 1 2.47902757992291 -10.6060248806369 8.24493476820459e-35 718.431855451565 53.371979571149 13.4608433343537 8.04150504832511e-36 444.156814868559 289.739009979079 1.53295483028202 0.125872615149118 CYCS essential 1.17432605903538e-30 1 1.20405455088572e-31 13.4608433343537 1.53295483028202 0.511042682536222 7.55116524317343 6.74908509110213 1.1188427973932 0.263713083753985 -3.36842258431194 26.9677437294991 -0.124905613836256 0.900645545484929 CD8B other 1 1 1 1.1188427973932 -0.124905613836256 0.00211086479429019 6.09233427068942 4.90332326874821 1.24249084483568 0.214591819960756 -37.9290388030888 14.3296202018944 -2.646897703407 0.00835921037980633 SLFN12 other 1 1 1 1.24249084483568 -2.646897703407 0.0361186893021236 192.547965555503 82.8471195182069 2.32413591052116 0.0204903970952895 75.7753825949025 180.869217947147 0.418951237003995 0.675419290986508 CALB2 other 1 1 1 2.32413591052116 0.418951237003995 0.299793535515391 0.897911767879465 1.96372021454176 0.457250356354352 0.647680256900034 6.99973984468654 4.54234365092942 1.54099741952688 0.123919911902373 CCL11 other 1 1 1 0.457250356354352 1.54099741952688 3.44510459432724e-06 153.449511791851 31.9377038006887 4.80465072722422 2.01531553727124e-06 216.004725953057 71.3069878012506 3.02922241723509 0.00257003135180222 FRMD3 other 0.0218626337556006 1 0.0190346552495269 4.80465072722422 3.02922241723509 0.00135729580549432 43.6179071208437 13.2239615695896 3.29839941618927 0.00103752861011243 240.211773518876 148.728303079945 1.61510464749777 0.106882024851955 SNTB1 other 1 1 1 3.29839941618927 1.61510464749777 1.18133908606435e-42 60.7995663794008 4.1096239262227 14.7944355665857 1.07416053714599e-41 181.519738833541 46.2839909879968 3.92186877057805 9.94351721806768e-05 MTBP essential 1.74932691864409e-38 1 1.62821254220589e-37 14.7944355665857 3.92186877057805 1.58076056836645e-50 57.5521875956115 4.10446562060404 14.0218466702961 4.3656557896691e-38 -31.2054933927764 10.2108178427607 -3.05612085861472 0.00235807107633756 TEFM other 2.39406188079099e-46 1 6.56943883229407e-34 14.0218466702961 -3.05612085861472 1.18398133822409e-78 303.793947709607 13.4156825216903 22.6446882011734 7.00081404076756e-80 158.100326998647 148.056276702669 1.0678394089036 0.286080013756663 MRPL13 essential 1.84061738840318e-74 1 1.09030677870914e-75 22.6446882011734 1.0678394089036 1.08927403922286e-14 184.346265771675 25.426861284133 7.25005983678808 1.44454382110408e-12 -32.1485857684538 55.7874291926137 -0.576269353754524 0.564672351691156 MALT1 other 1.11073273779555e-10 1 1.75049820241392e-08 7.25005983678808 -0.576269353754524 0.0836583115289739 58.715835915484 28.0483239152718 2.0933812691572 0.0367801590835243 -11.436721192904 66.8301923329267 -0.171131053101418 0.864184705273389 ISG20 other 1 1 1 2.0933812691572 -0.171131053101418 0.024248295997641 70.7979602766591 28.6331275247541 2.47258914400644 0.0137235999103947 -55.4984764584523 105.359789369909 -0.526751968567459 0.598584165893667 MBOAT1 other 1 1 1 2.47258914400644 -0.526751968567459 0.0410628039114882 158.595532157702 66.9864473832082 2.36757640318537 0.0182591240955481 -68.2581807098007 245.072988078239 -0.278521844635156 0.780719214618028 ID4 other 1 1 1 2.36757640318537 -0.278521844635156 0.0531701412357221 -4.87461169161254 6.85031028159182 -0.711589912169615 0.477022105715077 21.7715674444666 12.7706190188603 1.70481692487367 0.0887963853378101 CXCR6 other 1 1 1 -0.711589912169615 1.70481692487367 4.09014051788514e-07 157.46979394715 37.6291761510555 4.18477920736334 3.34129639420099e-05 1139.3433493303 288.092739519198 3.95477980886213 8.70134447800188e-05 CEBPB other 0.00282424202759969 0.985253235244153 0.288487530675314 4.18477920736334 3.95477980886213 0.00668519014207582 0.684867317923466 5.62523437803145 0.121749116907576 0.903144298656497 -27.3535811664044 10.0598033365414 -2.71909700928694 0.00676272844229308 AZU1 other 1 1 1 0.121749116907576 -2.71909700928694 0.35885396648928 -1.37760619410541 177.792729558635 -0.00774838317362736 0.993820608160559 -1095.74553129609 809.39639752351 -1.35378108260515 0.176372553986974 TPSAB1 other 1 1 1 -0.00774838317362736 -1.35378108260515 2.05005021228056e-22 187.954316104808 20.2114459186664 9.2993997985677 3.9185211543289e-19 -322.711760640013 94.7075099171423 -3.40745692630233 0.00070661863345863 PAIP1 other 2.54513733854631e-18 1 5.33585025584966e-15 9.2993997985677 -3.40745692630233 1.43179369007675e-19 277.650455333047 28.6669886304687 9.68537222071337 1.41426770545352e-20 337.582214620513 97.3084163292262 3.46919852727191 0.000563308652145396 CLEC7A other 1.68135533025713e-15 1 1.95536652956004e-16 9.68537222071337 3.46919852727191 2.03764953787288e-09 24.3598111488446 3.78446829065207 6.43678564014271 2.78001841983573e-10 24.5156476263648 17.7333957011469 1.38245647023933 0.167426179822203 C5orf34 other 1.64336435229448e-05 1 3.15976893598529e-06 6.43678564014271 1.38245647023933 0.00999445012807637 -129.429580915344 135.202837891419 -0.957299291448957 0.338839115620992 -790.990149868965 263.738908603587 -2.99914090816938 0.00283062266791708 SERHL other 1 1 1 -0.957299291448957 -2.99914090816938 0.0106710128661246 -149.789476081336 54.6851612442171 -2.73912470354425 0.00636235907477779 -233.701852668076 106.63562396671 -2.19159267770623 0.0288321295867751 NEGR1 other 1 1 1 -2.73912470354425 -2.19159267770623 1.37907685816669e-09 113.591807297067 18.5522557455084 6.12280300871598 1.80902398996467e-09 -111.212164136891 87.0818401773186 -1.27709938042694 0.202134927662612 ZNF131 essential 1.12105157800371e-05 1 1.99227812014809e-05 6.12280300871598 -1.27709938042694 0.12783396321182 -9.94270878903232 14.9050019676031 -0.667071954142869 0.50501216865714 -126.643253216863 62.4656456016914 -2.02740645673298 0.0431133203155226 MACROD2 other 1 1 1 -0.667071954142869 -2.02740645673298 7.2801532172222e-49 234.139836323635 32.4339085248568 7.21898306348722 1.80695013828402e-12 -485.591506640857 60.0433980687788 -8.08734219346845 4.105456256675e-15 DPAGT1 essential 1.09762870056059e-44 6.16844802565419e-11 2.18586758228217e-08 7.21898306348722 -8.08734219346845 9.83915389991862e-08 1345.82477061383 532.766958772625 2.52610404690693 0.0118281584433131 -3148.68032257899 955.802963593033 -3.29427763096961 0.0010537082393193 BSG other 0.000711862784659112 1 1 2.52610404690693 -3.29427763096961 2.61141254817164e-38 59.768078064478 9.70225767976236 6.16022373732109 1.42214776430684e-09 -125.731561647259 17.9532654365012 -7.00326980024654 7.47830139944652e-12 HINFP essential 3.79594928002229e-34 1.08786850457749e-07 1.57289542732336e-05 6.16022373732109 -7.00326980024654 0.000442445152143936 251.556779821353 238.315154213054 1.05556350645021 0.291638832003926 -2120.23480568789 633.303502206111 -3.34789685877633 0.000870920169493231 CERS6 other 1 1 1 1.05556350645021 -3.34789685877633 6.36388613326653e-08 100.979784071084 19.0271340862652 5.30714628978082 1.62950847166928e-07 -79.1973356793886 77.7919199869304 -1.01806634535687 0.30910317394471 SPTLC3 other 0.00046749107534976 1 0.00164335929367847 5.30714628978082 -1.01806634535687 3.92825190393513e-36 203.088734612204 21.1237453978078 9.61423889502476 3.00700134465642e-20 -257.033058405174 50.5640410916562 -5.08331717275635 5.18634905408466e-07 COPRS other 5.64725493709714e-32 0.00666964488355287 4.14545205374334e-16 9.61423889502476 -5.08331717275635 3.42916218291332e-40 133.56561392802 9.686711089342 13.7885410947146 3.09876335495733e-37 -167.928586564565 57.4519730931467 -2.92293854368245 0.00361388650623969 TP53RK essential 5.02646592771434e-36 1 4.65465243548141e-33 13.7885410947146 -2.92293854368245 0.0979805810897839 4.7317214599198 2.24899022531919 2.10393153631792 0.0358427965924683 8.32413577990722 7.4000320413995 1.12487834286903 0.261136659736608 CLEC12A other 1 1 1 2.10393153631792 1.12487834286903 8.42578173557802e-11 55.6244936612795 11.7761841631106 4.72347348604869 2.95208494182678e-06 -124.539496427107 37.9936976362378 -3.27789881415289 0.00111235028627637 BPGM other 7.29335667031633e-07 1 0.0275960900361967 4.72347348604869 -3.27789881415289 1.2947338409532e-19 137.233437608514 19.5686259445277 7.01293172027188 6.99287726847672e-12 -277.422699817683 63.0058643255263 -4.40312505490521 1.2863498743611e-05 POP7 essential 1.52144173650411e-15 0.154336257925844 8.33061468993632e-08 7.01293172027188 -4.40312505490521 4.74754434358532e-12 -2.58958391442567 7.99431190916028 -0.323928306006974 0.746117273082307 -110.714889895689 16.1358556998039 -6.86142042637598 1.86819129356096e-11 ALG14 other 4.36869030496721e-08 2.70177824874786e-07 1 -0.323928306006974 -6.86142042637598 1.06568740596169e-30 173.018098558612 48.1940028118171 3.59003378976829 0.000361172805932828 -853.821608967602 94.1596926488807 -9.06780369548871 2.32012022702619e-18 SUCLG2 other 1.46713185178746e-26 3.55303211566791e-14 1 3.59003378976829 -9.06780369548871 6.41271553381849e-06 -17.2772431881742 11.9898393897586 -1.44099037748012 0.150164851555061 -123.441814202143 24.9658735052179 -4.94442199974871 1.01999046782063e-06 STARD5 other 0.0395921057057954 0.0129446990271116 1 -1.44099037748012 -4.94442199974871 0.000208166775978472 11.1743526296876 5.4828182640406 2.03806730253586 0.0420254891382563 -22.2607852377714 10.2865016106652 -2.16407735888469 0.0308920688151637 CSDC2 other 1 1 1 2.03806730253586 -2.16407735888469 0.824346220146264 -0.239595665425775 8.90270199257484 -0.0269126907342968 0.978539539951912 -25.0570453077666 41.2990579033319 -0.606721958801513 0.544296231225225 RCAN2 other 1 1 1 -0.0269126907342968 -0.606721958801513 0.00613141900722082 -67.6604655867381 25.5713291966496 -2.64595027761025 0.00838323203830072 -130.090050465054 52.3326538543698 -2.48582941784428 0.0132258013667317 IL16 other 1 1 1 -2.64595027761025 -2.48582941784428 5.99575081898383e-18 661.519432073801 144.550831422566 4.57637929552946 5.87770977877918e-06 -2955.0881255028 464.554839278678 -6.36111794700323 4.27952621217719e-10 GNB2 other 6.75960947332237e-14 6.04354691683663e-06 0.05387508783229 4.57637929552946 -6.36111794700323 6.92036503987414e-19 13.4625262310589 3.56787965694012 3.77325681511485 0.000178925563116501 -46.0971164627691 7.39089313226334 -6.23701569456364 8.99748624121928e-10 CFAP53 other 7.97433663544697e-15 1.26180747046859e-05 1 3.77325681511485 -6.23701569456364 1.31305099231761e-29 76.7313125180788 21.1987305490447 3.61961827575268 0.000322900226377505 -295.040812034407 39.2604308510644 -7.51496623034151 2.39158690183904e-13 C2CD2L other 1.7900824178266e-25 3.53643955174939e-09 1 3.61961827575268 -7.51496623034151 6.3426461730147e-10 -37.4687587718913 141.39332203272 -0.264996664858194 0.791113528990331 -1734.24796302083 274.408007698172 -6.31996120509854 5.49451882479767e-10 GNG12 other 5.24980823740427e-06 7.74287592790487e-06 1 -0.264996664858194 -6.31996120509854 1.96652922410181e-06 32.7748572291941 6.37228446778826 5.14334496441115 3.76816415022111e-07 69.7062888867142 29.204224658936 2.38685634358676 0.0173325595913577 PRSS27 other 0.0128021052489028 1 0.00372483026249357 5.14334496441115 2.38685634358676 0.33426902855463 372.650919194218 253.410821896076 1.47054066754514 0.141996731082781 404.802518659469 534.395166910772 0.757496593765151 0.449082206972996 SYNPO2 other 1 1 1 1.47054066754514 0.757496593765151 4.10094444505289e-18 8.26216379930911 1.38380134888833 5.97062851972684 4.27698800169465e-09 -8.69636059294702 2.58962977154538 -3.35814821427443 0.000839787728641751 DNAJB7 other 4.64103882846636e-14 1 4.64095968063886e-05 5.97062851972684 -3.35814821427443 1.6919015210197e-29 40.0000830595325 6.47994900020697 6.17290090682117 1.34084715800824e-09 -116.824175332967 16.6783640936083 -7.004534418201 7.60855086197958e-12 CLP1 essential 2.30301635041201e-25 1.10673980838355e-07 1.48498822749412e-05 6.17290090682117 -7.004534418201 8.10622975554471e-05 -24.4999200356344 15.1047324587423 -1.62200291217038 0.105382104078745 -119.162102972473 27.9184810429525 -4.26821583843126 2.32472346283515e-05 TTC36 other 0.446247948042736 0.274038401799008 1 -1.62200291217038 -4.26821583843126 3.37053122695573e-40 127.940112257597 9.11500090676404 14.0362149786135 2.27578748513244e-38 -51.9694744826562 48.5543052520564 -1.07033710425617 0.284946655114536 RSPH9 other 4.94086172559441e-36 1 3.42779111010648e-34 14.0362149786135 -1.07033710425617 1.58602153174164e-05 -13.7164767838984 75.4950502212211 -0.181687100594084 0.855895472578387 -654.059224487949 145.628843969053 -4.49127526293447 8.63814112231331e-06 COPS9 other 0.0947806467368802 0.104728822966927 1 -0.181687100594084 -4.49127526293447 1.03696331988056e-58 316.268504106946 17.8174399161741 17.7505020695957 7.50565160369091e-56 -135.076577560947 95.5948624192868 -1.41301084747096 0.158229724461446 GTPBP2 other 1.59039064370082e-54 1 1.15624562954858e-51 17.7505020695957 -1.41301084747096 4.82325349177075e-09 4.88707344350693 8.92105084484381 0.547813652057768 0.584048338400418 -101.714849961659 17.8052710688747 -5.7126257481958 1.84800561256629e-08 FGGY other 3.80565274115324e-05 0.00025049716078336 1 0.547813652057768 -5.7126257481958 0.000348718334537411 37.3368050380308 9.58050667892494 3.89716392768284 0.000109948609117331 19.5858047428662 18.8737687316844 1.03772622316742 0.299876151147344 IL17D other 1 1 0.9053168474721 3.89716392768284 1.03772622316742 0.000485500763018563 4.67741248303614 1.73032920809988 2.70319223714228 0.00708282295610103 -14.0798108200753 7.87622049869729 -1.78763543026811 0.0743924044432534 PRSS30P other 1 1 1 2.70319223714228 -1.78763543026811 0.00287328011000476 -0.719432164655841 10.5631984598983 -0.0681074172171491 0.945725619726849 -71.2521481656132 24.0685026920728 -2.96038972914924 0.0032090218419521 FUT9 other 1 1 1 -0.0681074172171491 -2.96038972914924 5.20004999506224e-21 547.623804615728 124.457238101721 4.40009607290294 1.30380524862087e-05 -1819.95111249356 270.248140905198 -6.7343705173979 4.21614759279667e-11 ZNF24 other 6.28478042403222e-17 6.06324185320089e-07 0.116390694544385 4.40009607290294 -6.7343705173979 1.0696183264507e-11 65.9740633626869 16.6852673250361 3.95403094703155 8.71968611177827e-05 -118.469266173857 38.0177843912677 -3.11615387563376 0.00193079642883382 MANEA other 9.67790661772594e-08 1 0.724605915888774 3.95403094703155 -3.11615387563376 0.552212375931054 125.170554438055 117.49887413042 1.06529152184999 0.287214883133893 37.1484314848631 228.305855596741 0.162713441526786 0.870804264945048 C2orf54 other 1 1 1 1.06529152184999 0.162713441526786 0.703332973000653 -4.35296826109919 8.71968469585305 -0.499211658785024 0.617831362303687 -13.6947878381861 16.9427587264442 -0.808297400635899 0.41927142971949 AGXT other 1 1 1 -0.499211658785024 -0.808297400635899 2.43041828551889e-15 168.142779233501 73.5546217458971 2.28595804372932 0.0226396344070196 -1217.05593725265 180.850929113931 -6.72960843063149 4.31715613855275e-11 AFF1 other 2.53687060642462e-11 6.20720709601115e-07 1 2.28595804372932 -6.72960843063149 2.68926871172536e-19 277.856190700873 34.7227510247868 8.00213642353756 7.75993040598586e-15 -258.185285133308 95.3790928294276 -2.70693794073967 0.00700975539968106 FIBP other 3.13676302535646e-15 1 9.89623924675377e-11 8.00213642353756 -2.70693794073967 0.000484669176129087 19.6763891102681 5.24280514657439 3.75302696937431 0.000195254912299275 -5.61986475501288 22.2216979047109 -0.252899880968209 0.800449729237755 CARNS1 other 1 1 1 3.75302696937431 -0.252899880968209 1.68743094404834e-19 48.517452858822 10.0941412065981 4.80649634929899 1.99757172866262e-06 -76.2518727052619 21.5607033443978 -3.53661341595679 0.000440413778562126 BANP essential 1.97783780951906e-15 1 0.0188730576924044 4.80649634929899 -3.53661341595679 4.30432316354959e-41 1116.80221408 78.7081395063814 14.189157831503 1.24153633622319e-38 -442.233844612848 334.406049265266 -1.32244570809797 0.18662556938656 PPP1CA essential 6.3320898058978e-37 1 1.87198848775732e-34 14.189157831503 -1.32244570809797 0.790899626110658 4.23472291562655 7.09771508399146 0.596631854831389 0.551007953928281 -2.76273034892106 19.5344871289345 -0.141428353387834 0.887585296190546 CTSW other 1 1 1 0.596631854831389 -0.141428353387834 0.000247119761229352 4.91912864987149 5.88832891901055 0.835403170836809 0.403856150613924 54.6361416862818 13.4461883656212 4.06331818361058 5.54805454728144e-05 NIPAL4 other 1 0.638081753482838 1 0.835403170836809 4.06331818361058 0.654999631370775 1554.33666768478 2869.79247546723 0.541619884006323 0.588303370185722 -4847.92318265122 8443.38546428347 -0.574168170239119 0.566092647282793 MUCL1 other 1 1 1 0.541619884006323 -0.574168170239119 0.251311287540852 27.6125119918591 21.734066814954 1.27047147811565 0.204473098615406 -48.4050885643065 74.6015455382775 -0.648848334374925 0.516716928002063 PDE3A other 1 1 1 1.27047147811565 -0.648848334374925 0.0257218800450787 113.767488346043 69.2337838067587 1.64323661210811 0.100917157924411 -116.621651617031 117.359126188631 -0.99371608671988 0.320806998114515 RASGRP1 other 1 1 1 1.64323661210811 -0.99371608671988 0.0846467500077485 5.43504804606616 6.41496671727051 0.847244932921289 0.39723256723968 55.0228900162743 27.2675516649638 2.0178889066514 0.0440950565153655 KLHL6 other 1 1 1 0.847244932921289 2.0178889066514 1.7271627502508e-20 169.636730460407 23.2336059919272 7.30135177980331 1.04998929150512e-12 -250.44699809733 59.795110133033 -4.18841937978092 3.28985602107263e-05 CHCHD1 essential 2.06516850047488e-16 0.383761704858123 1.27531699346211e-08 7.30135177980331 -4.18841937978092 8.93593793408498e-39 318.995119335478 22.9793247886261 13.8818317017465 1.09331636342168e-37 32.6633132625786 75.0349524792584 0.435307975594542 0.663512828342501 MRPL52 other 1.3013406413408e-34 1 1.64391048404084e-33 13.8818317017465 0.435307975594542 1.1745419229945e-06 21.2091141755228 13.9030402649603 1.52550188817161 0.127728211116522 -118.968065688246 31.8392309725566 -3.73652447167423 0.000206759141794 SMPDL3A other 0.00779073657522251 1 1 1.52550188817161 -3.73652447167423 4.52508197707706e-10 71.7771567178494 27.7577142534765 2.58584536400938 0.00997286917121758 -436.099223027162 82.6058723162179 -5.27927628870936 1.87737606128581e-07 RND1 other 3.77844345085935e-06 0.00245297956167604 1 2.58584536400938 -5.27927628870936 8.78232479635168e-25 237.478721683308 22.6741591307524 10.4735403996182 2.42759841620367e-23 -103.660029875257 95.34000190473 -1.08726691634474 0.277442709564498 RAD9A essential 1.13133908026602e-20 1 3.4386931565525e-19 10.4735403996182 -1.08726691634474 0.0565806286454914 16.9940279592799 43.7781279176708 0.388185351169856 0.698034743259523 -256.958109948277 120.119995951235 -2.13917847660097 0.0328774595498359 EFEMP2 other 1 1 1 0.388185351169856 -2.13917847660097 2.55787522375008e-10 7.34335961964542 4.26975987688124 1.71985306700883 0.0860440356574927 -64.0977415000804 11.2241008646939 -5.71072393885054 1.87792752371177e-08 AGAP5 other 2.16447401433732e-06 0.000254477958738182 1 1.71985306700883 -5.71072393885054 4.22396516678302e-13 137.011758399175 36.0981065670984 3.79553864257397 0.000163847848425251 -555.923055770854 103.644448689624 -5.3637513904448 1.20654131858658e-07 WASHC2C other 4.04571383674478e-09 0.00159154865334755 1 3.79553864257397 -5.3637513904448 7.64477157323822e-30 255.430001862921 22.4589349236331 11.3732019230412 7.96537767561919e-27 -184.120414775493 92.7045268888016 -1.98609950295463 0.0475656898259228 TMEM134 other 1.04481093091447e-25 1 1.15274945721561e-22 11.3732019230412 -1.98609950295463 0.0420591700050849 13.6064047458039 20.8030660691938 0.654057661526776 0.513357280479719 -210.471451748188 85.9389732399694 -2.44908036264854 0.0146436987182 ZMAT3 other 1 1 1 0.654057661526776 -2.44908036264854 5.14488450751018e-07 -7.04643900498818 12.0065300922977 -0.586883883255206 0.557526062694866 -181.631825350574 33.8976930023669 -5.35823559844889 1.24464822855169e-07 ZFAND4 other 0.00351858651468621 0.00164007297076256 1 -0.586883883255206 -5.35823559844889 0.612237330352459 1.21348667895929 5.59241826581561 0.21698782553102 0.82829918513243 -10.0955139906162 13.2816582698312 -0.7601094521117 0.447518452941658 THEMIS other 1 1 1 0.21698782553102 -0.7601094521117 3.60926786382284e-06 100.083065806345 22.8968276462844 4.37104507892759 1.48168378838959e-05 264.115275509111 66.8603755288567 3.95025115279408 8.83444861035298e-05 SLFN11 other 0.0228683211851815 0.999706204747543 0.131603154084763 4.37104507892759 3.95025115279408 0.0113024816671552 11.8848035999014 5.69581065172172 2.08658684893412 0.0373975131608042 31.523561690123 11.0010061296636 2.86551623720321 0.00432674207532794 FAM71D other 1 1 1 2.08658684893412 2.86551623720321 0.0839382315938099 -56.2001871711474 31.7767890474335 -1.76859238632503 0.0775264212472626 -156.116594534675 85.1218518917636 -1.83403663178268 0.0671986635978569 CCL19 other 1 1 1 -1.76859238632503 -1.83403663178268 1.09292129484454e-23 662.169477148286 67.827127335436 9.76260536398007 1.00601363700678e-20 -647.412682063811 287.45782537399 -2.25220058358652 0.0247426138030621 CORO1B other 1.38451269630907e-19 1 1.39242347498108e-16 9.76260536398007 -2.25220058358652 2.69428033654086e-29 24.3685010130076 4.8523636028044 5.02198578006891 7.05656568743111e-07 -73.5063230913048 11.1151769510534 -6.6131491576784 9.41891586012723e-11 FUT10 other 3.66341297359461e-25 1.3472817246326e-06 0.00685333659563309 5.02198578006891 -6.6131491576784 0.00355560682932662 71.5075960232151 23.0416166861522 3.10341053742945 0.00201264631168885 -16.8207946847142 60.2004333286425 -0.279413182840182 0.780034148941467 LRRC20 other 1 1 1 3.10341053742945 -0.279413182840182 6.33092048417649e-22 147.015817255823 17.8898632972208 8.21782787343386 1.59991226462042e-15 -169.778754209562 48.7538598201709 -3.48236539293078 0.000538055353792644 MUS81 other 7.78956456373075e-18 1 2.06468677749265e-11 8.21782787343386 -3.48236539293078 1.57683361127354e-07 6.116654913105 1.23295641074095 4.96096606483369 9.40292755464538e-07 -4.23349547868149 4.17779126467716 -1.01333341243621 0.311353075295188 TMEM217 other 0.00112570151508818 1 0.00906442216267815 4.96096606483369 -1.01333341243621 1.21192586644152e-38 18.4767556904293 4.02155860779785 4.59442656252793 5.49503501842263e-06 -63.9473351402648 8.2851348766057 -7.71832155935439 6.41714843103983e-14 ZNF596 other 1.76383690601899e-34 9.54743343570105e-10 0.0504554115391566 4.59442656252793 -7.71832155935439 1.08379248952224e-20 3678.75681756246 448.950210735724 8.1941309517014 1.90592327223327e-15 -3592.96997317178 1219.84013515109 -2.94544331641191 0.00336663226781876 CFL1 essential 1.30065936667564e-16 1 2.45692569023591e-11 8.1941309517014 -2.94544331641191 5.33530289375684e-12 160.495029008164 25.2126885348348 6.36564517054253 4.15815848701242e-10 -206.438594160563 82.0111963327693 -2.5172001311006 0.0121175666312131 TMCC1 other 4.90154276849441e-08 1 4.69955072202143e-06 6.36564517054253 -2.5172001311006 1.15981862158046e-26 40.1257635830069 7.77536341227936 5.16062870060038 3.45523392154721e-07 -89.5598351249115 14.6904440086632 -6.09646890673262 2.05645153183824e-09 NAA16 other 1.5323523628321e-22 2.86052408078699e-05 0.00342448233964544 5.16062870060038 -6.09646890673262 0.00033393815617459 -2.63948760637327 6.73017658057417 -0.39218697678629 0.695074805131755 -86.9475277844859 21.6616379260571 -4.01389442854159 6.81684077666432e-05 EFCAB12 other 1 0.777937869432933 1 -0.39218697678629 -4.01389442854159 5.95714724796083e-93 315.24625509775 23.6388635495301 13.3359310796485 2.63966714701025e-35 -444.747883113343 50.1244869147072 -8.87286654664685 1.02677744432402e-17 FAM192A other 9.29493685099329e-89 1.56819719071607e-13 3.94841411849793e-31 13.3359310796485 -8.87286654664685 1.87549342707024e-08 92.2057859825028 19.5268004589459 4.72201199455899 2.9803138581612e-06 -183.761688793416 64.946718773026 -2.82942221354741 0.00483666180808664 RAB43 other 0.000142781314602857 1 0.0278540133183746 4.72201199455899 -2.82942221354741 2.26184301935408e-10 14.6576755417 2.44826144459298 5.98697315357053 3.91796898545769e-09 -11.1408326846022 7.58472190716709 -1.468851834116 0.142459612927152 HOXC5 other 1.92120946063936e-06 1 4.25765689649687e-05 5.98697315357053 -1.468851834116 7.78291645919566e-13 10.3231774069495 3.59262845815258 2.87343306640117 0.00422079241474268 -73.4219435730853 11.7838011732664 -6.23075207172161 9.374471001327e-10 RAB37 other 7.37976138660933e-09 1.31420708967603e-05 1 2.87343306640117 -6.23075207172161 5.83720963546757e-11 39.0320279475335 35.92791499381 1.08639836055775 0.277783934836814 -483.873636118634 80.3467485752985 -6.02231757598955 3.16692162858975e-09 DCP2 other 5.09471656983609e-07 4.38523637910823e-05 1 1.08639836055775 -6.02231757598955 5.66747064027796e-23 408.581653071023 47.1325451698926 8.66877974864846 5.30819054381506e-17 -411.955137362565 128.708048925551 -3.20069444608592 0.00145295571534399 SNX32 other 7.09964047107619e-19 1 7.03441410866372e-13 8.66877974864846 -3.20069444608592 2.08868654948213e-22 1915.07137847094 193.042194024921 9.92048079511424 2.07695593361415e-21 -790.787632839991 654.492697229415 -1.20824515871229 0.227485768829883 RPL38 essential 2.59247774521722e-18 1 2.89174574637098e-17 9.92048079511424 -1.20824515871229 0.93511993859116 -1.33273777667998 4.10305818248118 -0.324815714866136 0.745450185592438 4.71362958890483 35.892288548008 0.131327083883216 0.895566973140612 CYP7B1 other 1 1 1 -0.324815714866136 0.131327083883216 0.000238578526296202 63.9636063332958 18.2212903603425 3.5103774248891 0.000485514068470258 -45.62401624745 48.6635310264286 -0.937540192524707 0.348906979581841 OVOL1 other 1 1 1 3.5103774248891 -0.937540192524707 0.0150444972254359 89.4721161025658 41.9682065624062 2.13190230012621 0.033465580069265 -158.755247528223 120.581669701524 -1.3165786136582 0.188538413713551 RARG og 1 1 1 2.13190230012621 -1.3165786136582 7.96455754391813e-07 35.1466710007883 9.7582130552865 3.60175278011046 0.000345757977980107 -23.3066153040904 21.4415910903528 -1.08698161465157 0.277538095640432 CES4A other 0.00537050115186399 1 1 3.60175278011046 -1.08698161465157 9.06924351811174e-07 36.8076644323689 18.8872463164222 1.94881052619963 0.0518433249703376 -118.807505587615 41.4126268641218 -2.86887151538181 0.00428303958345516 CES3 other 0.00608546240065298 1 1 1.94881052619963 -2.86887151538181 8.55386159333545e-25 458.07034796848 48.3067381234929 9.48253526862971 1.0078819013077e-19 -641.063896564662 195.805253375794 -3.27398721695336 0.0011340093808942 SSH3 other 1.10225060491721e-20 1 1.3816045103126e-15 9.48253526862971 -3.27398721695336 7.52564443521876e-21 134.98090637434 26.0817502993075 5.17530092211351 3.2303072606318e-07 -223.824502630803 57.1874679354009 -3.91387327873364 0.000102621362959659 CES2 other 9.07065923776917e-17 1 0.00320640298690312 5.17530092211351 -3.91387327873364 1.18478508814784e-24 79.481726864446 12.7044085908057 6.25623194470995 8.10455809863719e-10 -101.866076757686 27.8330013493025 -3.65990269893184 0.000277426848546288 PDP2 other 1.5233966663405e-20 1 9.0536018519876e-06 6.25623194470995 -3.65990269893184 6.87574327079742e-08 165.723992759159 74.8655424377893 2.2136217459036 0.0272704167850558 -829.346323114231 184.23549706725 -4.50155554340052 8.26273425659194e-06 SP3 other 0.000503098135124247 0.100293068406513 1 2.2136217459036 -4.50155554340052 4.96003229842135e-19 104.185336689398 40.0901800246327 2.59877447857265 0.00960996418937407 -682.665611840663 90.4736118946589 -7.54546654593066 1.91187226057552e-13 DMXL1 other 5.7387573692735e-15 2.82995332010389e-09 1 2.59877447857265 -7.54546654593066 0.000648262207220845 9.06461609877392 5.72499249230418 1.58334113292883 0.113927027921394 -40.7991996235869 14.0787551641636 -2.89792663824698 0.00390836015979929 METAP1D other 1 1 1 1.58334113292883 -2.89792663824698 3.09075358613486e-20 39.1520180431788 23.0871836136631 1.6958334415467 0.0904895826581996 -356.766072869502 44.5888296954828 -8.00124325545251 7.47290486960872e-15 ZNF621 other 3.67676046606603e-16 1.1210851885387e-10 1 1.6958334415467 -8.00124325545251 0.0211822301648321 1.4140933459166 55.80251849306 0.0253410309087119 0.979792743392222 -338.463013005703 128.950936898047 -2.62474256602961 0.0089285291754457 EGFL7 other 1 1 1 0.0253410309087119 -2.62474256602961 6.23225568892047e-63 376.857036123797 20.1960783434409 18.6599115786352 2.05027112475366e-59 -196.100684084838 119.015314626296 -1.64769285953315 0.100041445288317 NADSYN1 other 9.60452924219533e-59 1 3.16664375218203e-55 18.6599115786352 -1.64769285953315 2.87791095373888e-29 680.223099810172 56.4340773380027 12.0534104905461 1.48302078865692e-29 209.742905887278 336.949277051695 0.622476200936022 0.533911992340118 DHCR7 other 3.91136877722651e-25 1 2.17544319488083e-25 12.0534104905461 0.622476200936022 0.0163173017648811 19.0377761764597 6.92165491879257 2.7504659506748 0.00615068653236421 4.04039709066766 15.6162852670029 0.258729718469282 0.79594237767215 LVRN other 1 1 1 2.7504659506748 0.258729718469282 9.62359026526828e-09 1.53927012961428 30.826972864993 0.0499325748381306 0.96019482443229 -322.047824754508 60.8830365274949 -5.28961502452445 1.79248577675898e-07 NBEA other 7.44865886531765e-05 0.00234439214742307 1 0.0499325748381306 -5.28961502452445 2.64511810183966e-09 158.604484235144 35.4539539336288 4.47353444786604 9.4275857056647e-06 -268.849083442269 92.5440754312987 -2.90509232697292 0.00382535980047635 RNASEH2C essential 2.11741704052265e-05 1 0.0851216713364465 4.47353444786604 -2.90509232697292 0.401052947443893 16.8020136801117 17.0625241600416 0.984732008143318 0.325243692874083 -125.716913612236 162.608291745002 -0.773127324954507 0.439821345634762 MYEOV other 1 1 1 0.984732008143318 -0.773127324954507 3.33565870609623e-29 289.932950690462 25.239707524588 11.487175531175 2.92209042377669e-27 -125.986489580069 102.237945802913 -1.23228698102891 0.218422211312891 ANKRD13D other 4.53215948397295e-25 1 4.23936878681523e-23 11.487175531175 -1.23228698102891 0.163303826427725 3.70399492073461 3.62645448448845 1.02138188596543 0.307568458007853 -42.3480161648218 29.8036506651316 -1.42090029978664 0.155970321947299 MRGPRF other 1 1 1 1.02138188596543 -1.42090029978664 2.96601442330228e-08 159.848692370362 42.2816307530848 3.78057065262791 0.000173749390144102 -224.680203192901 84.2019103747341 -2.6683504233215 0.00784944703081672 MYD88 other 0.000223103349148268 1 1 3.78057065262791 -2.6683504233215 1.15549165014486e-18 238.193792528024 33.8095501926808 7.04516301372116 5.61546714075034e-12 -190.534216015433 67.3301541219879 -2.82984969364878 0.00482869631499721 OXSR1 other 1.32488672605609e-14 1 6.70542931276998e-08 7.04516301372116 -2.82984969364878 2.51132961424104e-11 109.999585128586 15.7001091531979 7.00629429102919 7.22136915688085e-12 4.5186421939296 49.1790185060223 0.0918815041698374 0.926825825479447 LCLAT1 other 2.23257202706029e-07 1 8.59848425509803e-08 7.00629429102919 0.0918815041698374 0.0098202193193725 58.5765761552237 23.5143113292371 2.49110319817834 0.0130311343563955 -80.0372127345561 67.7448084904894 -1.18145160519263 0.237938644651864 MIR4435-2HG other 1 1 1 2.49110319817834 -1.18145160519263 6.0404752613131e-23 111.065082060939 22.9071733554994 4.84848481029524 1.63797083006541e-06 -442.612855383489 59.7937696168467 -7.40232399160839 5.30245394567677e-13 KAT5 essential 7.56388312221627e-19 7.81263564356015e-09 0.0155574469439612 4.84848481029524 -7.40232399160839 0.212179307615833 0.749569642927018 7.38085994326596 0.101555868650631 0.919146629835883 -37.539501922304 22.052931829558 -1.70224540720654 0.0892806708871882 SH3RF3 other 1 1 1 0.101555868650631 -1.70224540720654 0.0357962415425847 -77.3121995261294 30.9801335695454 -2.49554119424876 0.0128727507218149 -104.00591863593 61.2224342254692 -1.69882037445455 0.0899269030414875 GXYLT2 other 1 1 1 -2.49554119424876 -1.69882037445455 0.278875686789371 6.08495018807418 9.76264791290422 0.623288911201143 0.53335495138585 -20.5355160791303 18.9115633306422 -1.08587088862489 0.278015294642779 HPSE2 other 1 1 1 0.623288911201143 -1.08587088862489 6.51798949754742e-41 167.996695143598 23.88750619675 7.03282685768407 6.18513544071158e-12 -529.19354843957 56.2543204524429 -9.40716275982656 1.47466166147625e-19 DCAKD other 9.58209636034446e-37 2.26788216918432e-15 7.37762955368077e-08 7.03282685768407 -9.40716275982656 0.977017832724852 0.214825547885958 10.2762876827316 0.0209049760495664 0.983329122416826 -3.89658840011133 20.5713289413598 -0.189418409049744 0.849835548380806 ARPP21 other 1 1 1 0.0209049760495664 -0.189418409049744 5.90876946548999e-48 53.0612066938226 31.6585055996303 1.6760490013288 0.0943063555043215 -818.03243105209 61.1993820202743 -13.3666779638574 2.04589579876463e-35 TADA2B other 8.89033453777624e-44 3.20591871666418e-31 1 1.6760490013288 -13.3666779638574 1.9958996512908e-19 6.69754979821579 8.29359549248496 0.807556843625253 0.419701309351401 -128.515082303201 16.0774817424663 -7.99348333039914 8.00455679457221e-15 CCDC96 other 2.3356017719405e-15 1.20044338248199e-10 1 0.807556843625253 -7.99348333039914 4.95904411875791e-28 575.138940860066 51.2523043278197 11.2217186798347 3.264685352437e-26 -243.282013494374 204.443460478925 -1.18997209753967 0.234623203739973 GRK2 other 6.65801263384437e-24 1 4.70832921528465e-22 11.2217186798347 -1.18997209753967 1.11254431310807e-26 232.238584040866 38.5465225288717 6.0248906724833 3.17591446028807e-09 -748.036139505144 100.616486815665 -7.43452850699893 4.26511780790406e-13 RELA other 1.47033856420363e-22 6.29147527843928e-09 3.46460508472826e-05 6.0248906724833 -7.43452850699893 0.00350640307162943 -8.30729568013764 6.61845048315718 -1.25517229467506 0.209953161287906 27.0277773989249 12.7958186500347 2.11223510883781 0.03511975777747 EVC2 other 1 1 1 -1.25517229467506 2.11223510883781 0.00236640360167543 23.5150193362712 19.6392551755944 1.19734781823565 0.231719705999043 -236.115111347867 79.9347319103338 -2.95384879269661 0.00328128972507092 ZNF680 other 1 1 1 1.19734781823565 -2.95384879269661 6.26859882089057e-33 228.698389424557 18.3884693519748 12.4370541694921 3.24920422661333e-31 6.72473699417153 70.6718901903058 0.0951543389608387 0.924229466483589 FAM222B other 8.81114250264378e-29 1 4.79874972228523e-27 12.4370541694921 0.0951543389608387 0.0137916224921623 -54.0512282617323 19.284699648574 -2.80280373802602 0.00524841870024132 -83.084038731378 44.1794254938393 -1.88060477932118 0.060564624128392 BNC2 other 1 1 1 -2.80280373802602 -1.88060477932118 0.000133987354482655 28.6399309164059 8.49995583016382 3.36942114625717 0.000807061524459774 73.9247206302253 20.002005323788 3.69586546116494 0.000241497509523438 HPSE other 0.716832346482205 1 1 3.36942114625717 3.69586546116494 4.76972816133867e-10 53.8999050033115 8.46478959086262 6.36754220819548 4.11615530543083e-10 11.0946018870028 19.9115875372176 0.557193235660661 0.57762671001815 COQ2 essential 3.97795328655645e-06 1 4.65331357278956e-06 6.36754220819548 0.557193235660661 0.570102765091824 15.3880933439406 14.5076844387234 1.06068569446322 0.289309578967012 -4.80387695571464 164.237533224887 -0.0292495683622865 0.97667641528479 HSPA6 other 1 1 1 1.06068569446322 -0.0292495683622865 2.78684441407902e-16 548.984474212748 85.4139619069105 6.42733883262628 2.89336123384063e-10 -587.264062664077 203.023379048833 -2.89259328366722 0.00397750550597697 TRMT112 essential 2.9978085362248e-12 1 3.28656902551957e-06 6.42733883262628 -2.89259328366722 0.506558414523702 9.71865399307771 11.438534550941 0.849641529672892 0.395903042405264 -17.327436312238 34.815022681186 -0.497699986322335 0.618899255652798 LRRN3 other 1 1 1 0.849641529672892 -0.497699986322335 9.66730695460713e-41 939.570378783213 68.9410703455618 13.6286015588921 3.28597832651412e-36 -665.240760407174 275.361050453933 -2.41588546858942 0.0160529674959719 KDM2A essential 1.42003071856224e-36 1 4.92601010927732e-32 13.6286015588921 -2.41588546858942 1.28809387844855e-11 44.7555194855702 6.4278870092136 6.9627109844057 1.06353695906024e-11 -49.3833714500091 43.9149763275454 -1.12452232882188 0.261335406991797 ADCK5 other 1.16095901264568e-07 1 1.26135483344545e-07 6.9627109844057 -1.12452232882188 1.39485559720914e-26 197.638516101259 29.0894434867929 6.79416628203939 2.94716597373209e-11 -287.922440878096 59.1137636844515 -4.87064979342244 1.47229138529801e-06 MRPL57 other 1.84134887387578e-22 0.0185538160375255 3.44788947266917e-07 6.79416628203939 -4.87064979342244 1.98704497215605e-07 72.8425525882064 16.5111958307549 4.4117066586131 1.23601659551266e-05 -48.5048242088298 31.8628808784307 -1.52229876494516 0.128513159445386 NOC3L essential 0.00140563561330319 1 0.110574044634562 4.4117066586131 -1.52229876494516 1.70830614392853e-14 164.830860401501 29.2386232323749 5.63743576746081 2.80628970072944e-08 -223.890810403428 69.4982875731957 -3.22152988543245 0.00135322305561888 ESRRA other 1.72965997072763e-10 1 0.000294969110443672 5.63743576746081 -3.22152988543245 1.96833310228002e-12 161.483364768741 25.0129596243721 6.45598790362238 2.51516412861431e-10 -183.671237603435 92.6078574562101 -1.98332239454178 0.0478694231316582 RHOD other 1.83861995083977e-08 1 2.8615022291245e-06 6.45598790362238 -1.98332239454178 0.551031933579679 31.6462805055438 29.4140406270748 1.0758902833776 0.282455888529552 -0.953277897591515 106.344452074416 -0.0089640585756598 0.992851116334633 COMMD1 other 1 1 1 1.0758902833776 -0.0089640585756598 1.94704361183086e-08 223.570789792341 78.0918458349574 2.86292105663433 0.00436086878202041 -842.876912386544 194.276167768463 -4.3385502301604 1.71273811350617e-05 RAPH1 other 0.00014815054842421 0.203952854556315 1 2.86292105663433 -4.3385502301604 4.87647644505805e-32 168.837329981479 13.3861087873397 12.6128759794005 4.72213395025168e-32 266.458421262081 138.819180152015 1.91946401765443 0.0554662940405449 MTX1 other 6.80073405027796e-28 1 6.99064709995259e-28 12.6128759794005 1.91946401765443 0.0418429365435434 -52.6419268707801 50.6564560230569 -1.03919482339664 0.299177496265664 -412.858592662095 167.827814382605 -2.4600129256339 0.0142042106266922 ADCY5 other 1 1 1 -1.03919482339664 -2.4600129256339 0.000110538893387365 554.205123704051 130.321550236618 4.25259769161593 2.4866203516284e-05 52.7828302841045 425.28349573883 0.124112105955127 0.901272273599991 PARP14 other 0.597131102078543 1 0.217032224290127 4.25259769161593 0.124112105955127 0.328322667302315 -1.06667597559027 2.64307588779823 -0.403573722765428 0.686684794261243 11.668616677747 8.68183351910553 1.34402677177219 0.179499976828589 PARP15 other 1 1 1 -0.403573722765428 1.34402677177219 4.6343289964428e-14 116.863984700594 14.552472753279 8.03052420587844 6.29458823350899e-15 12.5551902829564 158.40679904046 0.0792591628579627 0.936856347246983 CKS1B other 4.61347451595881e-10 1 8.03755971536763e-11 8.03052420587844 0.0792591628579627 0.0120122718193013 35.2508035075642 11.8340482473475 2.978761178827 0.00303173311723384 13.7354278982482 40.432521284127 0.339712376621946 0.734212721370311 ABCD2 other 1 1 1 2.978761178827 0.339712376621946 0.00303566291525101 45.7356208562347 50.9909896643924 0.896935344013777 0.370150901856588 -577.197397473199 186.155748322742 -3.10061549360539 0.00203140133585351 AHSA2 other 1 1 1 0.896935344013777 -3.10061549360539 3.11340424940147e-14 127.257500651652 59.5033687439167 2.13866043785398 0.0329046179039827 -929.779504324035 140.734764016146 -6.60660861460901 9.32493899250841e-11 ABLIM3 other 3.12181044087485e-10 1.33393252287833e-06 1 2.13866043785398 -6.60660861460901 1.1111525956266e-20 24.8278200083145 3.55083441567834 6.99210864316563 8.02933823436024e-12 -34.7120466315916 10.1643255139214 -3.41508608554979 0.000685560235919868 MFSD4B other 1.3331608842328e-16 1 9.55089782977151e-08 6.99210864316563 -3.41508608554979 1.81389710878138e-09 304.279197599525 53.2627760063242 5.71279269340742 1.84461621214888e-08 -80.2558696983019 126.008572292839 -0.636908015367324 0.524456680614276 VANGL1 other 1.46726137129326e-05 1 0.000195326410704444 5.71279269340742 -0.636908015367324 0.000612910704391547 103.16146994054 41.4860319436878 2.48665551047564 0.0131932730622842 -168.620193309366 96.0114122622991 -1.75625156776887 0.0796070938701573 GLRX other 1 1 1 2.48665551047564 -1.75625156776887 1.99297769078965e-11 109.866260405684 15.4347060175519 7.11813106649047 3.4600388275878e-12 20.352256614991 50.8013967667412 0.400623957416763 0.688853716899973 IQCB1 other 1.78012767341332e-07 1 4.15550663193294e-08 7.11813106649047 0.400623957416763 0.00295937920401123 95.9184771521813 50.3775488558216 1.90399253895214 0.0574769977559077 -405.958268833851 181.571881502725 -2.23579920786225 0.0257993465985526 SYT12 other 1 1 1 1.90399253895214 -2.23579920786225 4.02955200756697e-11 425.559684958133 153.610371956372 2.77038379334828 0.00579077302576449 -2967.82028551746 505.40566839197 -5.87215472861644 7.49863368978942e-09 GOLGB1 other 3.54882645306423e-07 0.00010292624602605 1 2.77038379334828 -5.87215472861644 0.0358958731475858 5.88595137607207 2.78375316600851 2.11439413808073 0.0349435643416819 -3.55033641268632 6.72977686767136 -0.527556333961309 0.598026017059985 DMRT2 other 1 1 1 2.11439413808073 -0.527556333961309 1.51061776360058e-06 2.19300870657676 2.25025518392377 0.974560006457941 0.330210914324836 -22.1012687777121 4.87012489161574 -4.53813182815105 6.98779381204726e-06 ZNF483 other 0.00992173747132859 0.0851881943626682 1 0.974560006457941 -4.53813182815105 0.000908337519302264 10.576577886411 2.81030756352457 3.76349479455064 0.000185837900814474 7.45288238890352 10.0131330312797 0.744310733276158 0.457011081632485 SLC2A14 other 1 1 1 3.76349479455064 0.744310733276158 2.43294646060516e-07 111.56470130232 42.8823570806604 2.60164573259046 0.00953713369200652 -353.935751040907 102.00691703997 -3.4697230473324 0.000563429720068979 GPR137 other 0.00170963147786725 1 1 2.60164573259046 -3.4697230473324 0.000155946644087957 448.221438532524 108.260020917341 4.14023048152512 4.02843167913373e-05 134.529363869919 229.797191868567 0.585426491838346 0.558506907592537 SNCG other 0.827141000242524 1 0.345156026268178 4.14023048152512 0.585426491838346 0.065220509826214 -77.9793120939545 49.5380711748485 -1.57412895263363 0.116046581533586 -230.650891138405 107.374974246943 -2.14808797632816 0.0321534373588713 MMRN2 other 1 1 1 -1.57412895263363 -2.14808797632816 7.91600020324637e-43 151.538882913613 32.7502045955315 4.62711255655147 4.64768059250888e-06 -820.64459952658 83.1080678002609 -9.87442761271854 2.98408399680755e-21 TNKS other 1.17323039012314e-38 4.6127970422651e-17 0.0428516150629319 4.62711255655147 -9.87442761271854 0.00038957610148606 57.2882583468264 15.8659437461869 3.61076903229249 0.000333364922305853 -52.7834256998417 50.3469013067052 -1.04839472400285 0.294919781619021 ZBTB21 other 1 1 1 3.61076903229249 -1.04839472400285 2.07020991775054e-27 263.047975484441 85.1463334260085 3.08936350985716 0.00210931403898569 -1234.25190789027 176.758729451972 -6.98269280231296 8.55503102720121e-12 PPP1R3B other 2.76041790432857e-23 1.24296045794206e-07 1 3.08936350985716 -6.98269280231296 2.80804674752242e-09 51.9285871193207 10.8108280836179 4.80338663399985 2.04872450605132e-06 -8.3596036061752 23.7666724866658 -0.3517363909847 0.725179834877246 FAM86B3P other 2.24419096061992e-05 1 0.0193440567861365 4.80338663399985 -0.3517363909847 4.43828381604413e-06 32.162025252048 11.5642757322934 2.78115344156272 0.00560440467329078 118.663205914953 23.8855493239025 4.96799149585417 9.07343634637009e-07 STOX2 other 0.0278555406898235 0.0115495771252945 1 2.78115344156272 4.96799149585417 7.18110247508432e-12 144.49551689568 46.1301859544556 3.13234195583648 0.00183166947270057 -630.199174677124 119.900401239321 -5.25602223314703 2.15087308690259e-07 MAP3K11 other 6.55993711098953e-08 0.00280344798146883 1 3.13234195583648 -5.25602223314703 0.349677333525583 61.5007917273275 58.7768529593518 1.04634373279324 0.295877523548099 -634.62230715467 650.154955018876 -0.976109314026908 0.329453931314889 TRIB1 other 1 1 1 1.04634373279324 -0.976109314026908 0.519498258011142 1.35938331243731 67.9635776381132 0.0200016444054144 0.984049560047151 -316.777283716208 286.829900596999 -1.10440816336399 0.269915375475612 CST9 other 1 1 1 0.0200016444054144 -1.10440816336399 3.65638414703092e-15 41.2095225794297 8.30375231466561 4.96275912597342 9.32025242569993e-07 -108.209239727318 21.3699249336836 -5.06362282802207 5.64669141716316e-07 SFT2D3 other 3.7949611062034e-11 0.00724922244135406 0.0089856553636173 4.96275912597342 -5.06362282802207 0.561636984863304 201.680227270712 190.268820829743 1.05997517823049 0.289624558218044 212.660378864192 299.406692004476 0.710272630983855 0.477838338192237 C1QB other 1 1 1 1.05997517823049 0.710272630983855 0.719940929771533 116.823441513606 157.541122473947 0.741542523495258 0.458683388559819 27.9644539847359 247.906441680239 0.112802449969435 0.910228636361812 C1QA other 1 1 1 0.741542523495258 0.112802449969435 0.109452549836623 -7.41102580607163 11.3902426004852 -0.650646879615713 0.515550687453374 -57.8489032502055 27.496282355464 -2.10388089932856 0.0358497796678397 NDNF other 1 1 1 -0.650646879615713 -2.10388089932856 0.113117588698022 17.7766164912943 20.0479792551431 0.886703655518489 0.375629571557475 141.247952873517 68.0516930838601 2.07559792376447 0.0383995394633159 OLR1 other 1 1 1 0.886703655518489 2.07559792376447 4.41974643107146e-18 884.973614920838 155.223072591159 5.70130200457868 1.9933058324268e-08 -1038.4778914315 281.44211711938 -3.68984536522302 0.000247996899367761 DAG1 other 4.9974072896125e-14 1 0.000210831957895782 5.70130200457868 -3.68984536522302 0.53729621826957 4.63382207961014 43.3511344749208 0.106890445561254 0.914915445368123 -197.445894342893 188.546855667583 -1.04719802217757 0.295475018823155 INSM1 other 1 1 1 0.106890445561254 -1.04719802217757 0.223071031653583 -1.49265314237001 11.4304980319403 -0.130585136203085 0.896152496058314 -39.1733051197355 23.5002228453362 -1.66693334686866 0.0961118205156131 DAB1 other 1 1 1 -0.130585136203085 -1.66693334686866 4.81063312807556e-13 94.680735833717 12.6518370473067 7.48355637838954 2.92784340789212e-13 -115.004370983348 76.1870972428192 -1.50949931347052 0.131751803610463 ARV1 other 4.59800314381462e-09 1 3.60798143154545e-09 7.48355637838954 -1.50949931347052 3.69080773183763e-21 265.188472798514 33.8078333555368 7.84399491117 2.32296013344421e-14 -616.497493613343 147.578176529769 -4.17742994330185 3.43392399287832e-05 NAA20 essential 4.47362805176039e-17 0.400017805930396 2.9332017605e-10 7.84399491117 -4.17742994330185 0.981561135519795 0.246327873472896 1.28003952076599 0.192437709521258 0.847474341726249 0.183237758674902 2.31707527542685 0.0790814871740179 0.936998172684934 CCDC36 other 1 1 1 0.192437709521258 0.0790814871740179 0.634586183477428 251.352004937251 620.702341838843 0.404947730972975 0.685673956201562 -1029.75354635519 1550.85182136464 -0.663992221674076 0.506974550397074 SAA1 other 1 1 1 0.404947730972975 -0.663992221674076 1.05721803641644e-21 298.294237438663 53.6112800286784 5.56402005844844 4.12854624160546e-08 -408.529573973474 90.0886274200945 -4.534751895691 7.08861628913125e-06 MINOS1 other 1.29509209461014e-17 0.0863747894830643 0.000430359660224953 5.56402005844844 -4.534751895691 1.02991478494428e-06 105.939334448495 38.3126847515464 2.76512426982083 0.00589265398119398 -329.101919742665 97.4897113370868 -3.37576053133178 0.00079126261052373 EHBP1L1 other 0.00686541195643857 1 1 2.76512426982083 -3.37576053133178 6.6270657842178e-15 35.0615910345236 4.25164097061046 8.24660202422722 1.29294865505494e-15 2.27710792661352 16.7651905653962 0.135823563575443 0.892012333964252 THAP2 other 6.82057610511696e-11 1 1.67023107259998e-11 8.24660202422722 0.135823563575443 1.84704609814543e-30 183.370434414416 27.2977805407414 6.71741184748481 4.67932657811248e-11 -240.456093675256 50.3238718852781 -4.77817156484732 2.27985671407329e-06 RNF26 other 2.53691781580275e-26 0.0284799700722036 5.43690955110889e-07 6.71741184748481 -4.77817156484732 3.31800844891046e-13 449.742151853664 72.6157535433302 6.19345155711014 1.18156524020815e-09 -308.900227140306 173.052581998333 -1.78500790669094 0.0748318289219981 PPP1R14B other 3.19524213630077e-09 1 1.31165557315507e-05 6.19345155711014 -1.78500790669094 3.77994287445273e-14 212.722986803265 39.389235974203 5.40053599776809 1.01322608774552e-07 -390.833015508521 100.017286214543 -3.90765466951543 0.00010553625179036 SSSCA1 other 3.7780529030155e-10 1 0.00103419986776185 5.40053599776809 -3.90765466951543 1.8767933617723e-05 -50.681156617713 182.460161261234 -0.277765602460206 0.781299402817661 -3113.77146142631 673.24319948846 -4.62503217825624 4.70047603400438e-06 AGR3 other 0.111312614286715 0.0578299566463559 1 -0.277765602460206 -4.62503217825624 3.42128310228565e-12 821.027807966078 153.306957256774 5.35545041567122 1.28435071779084e-07 -520.000986879557 283.073464471924 -1.83698245206283 0.0667841037830458 SMARCC1 other 3.16742389609605e-08 1 0.00130284536812703 5.35545041567122 -1.83698245206283 2.15130743107253e-27 99.9318196364069 9.14566863253671 10.9266827447573 3.29798169815688e-25 -110.0434847013 45.2423542059629 -2.43231119672364 0.0153321763361454 ZNF417 other 2.86790793636279e-23 1 4.72963555332678e-21 10.9266827447573 -2.43231119672364 0.200226847687909 -58.4931275211901 87.4389322595355 -0.668959764370993 0.503808087483111 -330.457463911822 184.819771107163 -1.78799844806763 0.0743389233853181 PTPRM other 1 1 1 -0.668959764370993 -1.78799844806763 0.000438256463804828 112.475558429414 66.6014360591765 1.68878578428064 0.0918486819693182 -409.699212074584 158.719698033017 -2.58127514827654 0.0101111440452253 FKBP2 other 1 1 1 1.68878578428064 -2.58127514827654 4.71064651792847e-11 298.116579071866 67.4929403994717 4.41700387192197 1.21383454867852e-05 -517.297936914635 160.84426633153 -3.2161416052493 0.0013785412946928 VEGFB other 4.13076593157147e-07 1 0.108626053761241 4.41700387192197 -3.2161416052493 0.0046351236885965 137.054060142573 43.5263876667148 3.14875797164716 0.00172996569197715 -8.96612971337473 97.0017392536991 -0.0924326695826005 0.926388438204539 PEAK1 other 1 1 1 3.14875797164716 -0.0924326695826005 0.071739936853372 16.5024897723301 7.89703233606804 2.08970776236517 0.0371070771227663 9.80339006813567 16.0074503207947 0.612426705794642 0.540510911283787 TNFRSF10D other 1 1 1 2.08970776236517 0.612426705794642 2.9149722706184e-10 13.8857833579181 15.8477453521785 0.87619929834431 0.381335009111384 -157.393158705283 28.7422033406885 -5.47602968497796 6.84415744645892e-08 MST1 other 2.45761312135837e-06 0.00091061514825136 1 0.87619929834431 -5.47602968497796 1.58436353101796e-25 101.82240097962 34.4719210791901 2.95377796745675 0.00328372802250272 -506.802220796302 62.520124071699 -8.10622544854668 3.88649110106637e-15 GMPPB essential 2.06204913561987e-21 5.84100747579265e-11 1 2.95377796745675 -8.10622544854668 2.34729779459709e-07 122.967996884657 39.1288580745977 3.14264210445966 0.00176636598120706 -321.023616719807 101.887029206916 -3.15078002782731 0.00171875859313714 MOB1B other 0.00165132399849905 1 1 3.14264210445966 -3.15078002782731 3.81064118344402e-22 132.617323556369 14.3723029126293 9.22728419812497 6.2111868570324e-19 -253.971677360222 72.3977791679545 -3.50800370231022 0.000489041251449436 ZNF622 other 4.7072850539084e-18 1 8.44100293870703e-15 9.22728419812497 -3.50800370231022 2.62765627104439e-07 401.963029592344 136.003610965617 2.95553203873362 0.00325760357160549 1611.99813160203 300.712981703172 5.36058710359636 1.23109296012799e-07 CSPG4 other 0.0018409359834937 0.00162294984933673 1 2.95553203873362 5.36058710359636 3.12204016092457e-19 189.824440098565 31.8285694368383 5.9639639310607 4.44402122962168e-09 -389.585034376993 69.1368604048931 -5.63498301912218 2.81737972632455e-08 SNX33 other 3.63249372723573e-15 0.000379641918122233 4.81998542564767e-05 5.9639639310607 -5.63498301912218 2.19793513644068e-09 17.2566198422842 2.73605723296377 6.30711215919681 5.88292561062933e-10 22.188109065477 8.20777032270383 2.70330530620497 0.00707965167773405 C2orf70 other 1.76955757834839e-05 1 6.60829033841993e-06 6.30711215919681 2.70330530620497 0.000113892496181305 78.2145147541644 18.20767955412 4.29568822988574 2.06744616689021e-05 52.7903237192079 45.8850917788491 1.15048966173239 0.250454304639934 NABP1 other 0.614450016898141 1 0.181542447914629 4.29568822988574 1.15048966173239 9.54600351459892e-11 6.30265009948304 0.959487656370722 6.56876621354664 1.18779575907065e-10 -1.72996135504035 2.88340536955219 -0.599971607637335 0.548774983903132 ADGRF3 other 8.23724643274741e-07 1 1.36549000462761e-06 6.56876621354664 -0.599971607637335 0.0125292056220307 -7.84069209637726 2.82037951847059 -2.78001313122179 0.00562280071040656 -11.8324918265406 5.25846265800881 -2.2501808220544 0.0248340399473078 XCR1 other 1 1 1 -2.78001313122179 -2.2501808220544 6.82266276026307e-12 96.5248060676182 15.6534581351565 6.16635667557897 1.37655270557906e-09 -217.422918289623 70.4458498329647 -3.08638363800221 0.00213078533031408 CCDC106 other 6.23659602915647e-08 1 1.5235685345349e-05 6.16635667557897 -3.08638363800221 4.24685863907108e-14 40.5036599588362 8.12387205297702 4.98575798519543 8.34259216627261e-07 -99.7136449942369 21.0232248153825 -4.74302329304291 2.70193002802772e-06 CEP83 other 4.23539212074559e-10 0.0336471346390292 0.0080697894024355 4.98575798519543 -4.74302329304291 0.655701596637779 -14.5370347986914 18.0409062634181 -0.805781848563144 0.420723985315844 -33.074564884838 47.1066061422956 -0.702121583221878 0.482906421618274 SULT1B1 other 1 1 1 -0.805781848563144 -0.702121583221878 2.84214858569511e-13 315.865401257201 73.0278474702895 4.32527333337748 1.81726431853728e-05 -984.9641525406 191.705903240928 -5.13789161360742 3.89728558217956e-07 NUDT4 essential 2.74750503779146e-09 0.0050333443293849 0.160210022322246 4.32527333337748 -5.13789161360742 6.22767145864424e-08 229.325285140162 42.0159582704408 5.45805200167237 7.54470578085258e-08 -88.1153321707025 152.770172718623 -0.576783612943844 0.564341633449521 PC other 0.000457609298781178 1 0.000776501118965348 5.45805200167237 -0.576783612943844 6.67882710378348e-11 28.3198241623625 10.4889176692426 2.69997582738272 0.00715113082289664 -126.20418017422 23.9536297989854 -5.26868709391032 1.98596181009059e-07 SCAI other 5.8145868765539e-07 0.00259207735453023 1 2.69997582738272 -5.26868709391032 5.06135342770307e-24 25.1449510852319 10.2105953246671 2.46263320459737 0.0141020062109 -133.383907524182 16.7836462675928 -7.94725445219431 1.1118817537054e-14 NMNAT1 other 6.44310291346601e-20 1.66459817347235e-10 1 2.46263320459737 -7.94725445219431 3.67744376526385e-06 116.42788353448 23.0062691185616 5.06070249524053 5.8484802385268e-07 97.2350766473828 83.6463602168722 1.16245436615866 0.245596758726562 LRFN4 other 0.0232892513654159 1 0.0057063621687306 5.06070249524053 1.16245436615866 0.17959659410566 86.9922860244698 72.1525034973358 1.20567245497839 0.228472815635956 -229.962868615091 206.921373083052 -1.11135386929214 0.266911543133095 SLC19A1 other 1 1 1 1.20567245497839 -1.11135386929214 0.49410320572083 -43.1718029080964 126.172755211346 -0.34216422424779 0.732361930738303 -241.703557415136 208.767566718471 -1.15776392480102 0.247477955436355 HSPB7 other 1 1 1 -0.34216422424779 -1.15776392480102 1.0263337639684e-33 155.921025994885 12.497638677248 12.476038875947 2.38531850464724e-31 -53.8174303177973 45.5029968737313 -1.18272276586833 0.237472282475829 RCE1 other 1.45072277536933e-29 1 3.52383102691536e-27 12.476038875947 -1.18272276586833 6.81707058620852e-15 593.015872863405 86.2956343715218 6.87191046432708 1.73685152235781e-11 -323.219816289457 176.696801431019 -1.82923410990911 0.0679107604023664 UQCRH essential 7.01340221909132e-11 1 2.0460110933375e-07 6.87191046432708 -1.82923410990911 4.39382514237697e-11 8.52698955262206 1.32289755996258 6.4456914962208 2.56071214008945e-10 -3.69464245546305 4.1078406318928 -0.899412315750097 0.368835460329378 SPDYE2B other 3.85777847500698e-07 1 2.91229791692374e-06 6.4456914962208 -0.899412315750097 7.17279732217695e-09 482.506891163622 82.3137226856548 5.86180378460408 7.95180239691722e-09 -26.4305104469735 167.453918248904 -0.157837515678117 0.874643512630488 PSMD1 essential 5.60267198835242e-05 1 8.54182613476848e-05 5.86180378460408 -0.157837515678117 0.56597439518964 1.54677018260823 13.8693509947953 0.111524337597965 0.911241552283947 -44.5213492453674 43.9128520203796 -1.01385692791498 0.311100086319286 MUC13 other 1 1 1 0.111524337597965 -1.01385692791498 0.224772776968984 -7.04060580720924 14.4940724464582 -0.485757597336259 0.627333914381154 40.2045238479739 29.5358451069473 1.36121122325757 0.174008445526538 SUSD5 other 1 1 1 -0.485757597336259 1.36121122325757 0.0101484652396891 -160.633616758847 72.9134383429848 -2.20307285473531 0.0280065336680021 -583.362801179096 231.655157959764 -2.51823791154444 0.0120791625097778 HEG1 other 1 1 1 -2.20307285473531 -2.51823791154444 9.40847609312237e-23 153.914302941951 15.4174686286674 9.98311114807535 1.50053081699818e-21 -45.5881238602365 56.6240327707234 -0.805102032291263 0.421137455681768 C11orf80 other 1.17502457927005e-18 1 2.09234017122226e-17 9.98311114807535 -0.805102032291263 4.28026223855969e-26 1246.17889804196 109.239573831076 11.4077605243042 3.63702857726718e-27 -20.4586279967623 699.507413714339 -0.0292471925181297 0.976678209022421 TOMM20 essential 5.61698813566188e-22 1 5.27332773417969e-23 11.4077605243042 -0.0292471925181297 9.67507542706134e-12 498.864087678629 72.5176175141636 6.87921231804389 1.67766594800477e-11 -62.1655615206205 152.025183198253 -0.408916208570206 0.682763879459325 AGFG1 other 8.77432590480193e-08 1 1.97780038610283e-07 6.87921231804389 -0.408916208570206 2.83076687526355e-20 220.289358707447 50.7811105901397 4.33801774217638 1.7167510690168e-05 -749.88455405397 116.088265181041 -6.45960685935412 2.34811037522128e-10 STAT5B other 3.37031104168878e-16 3.33431673281421e-06 0.151606286904873 4.33801774217638 -6.45960685935412 0.0457997768069402 -0.267132464897451 7.08368203384559 -0.0377109621269138 0.969932470546206 49.3196298985554 20.2158530257629 2.43965119036544 0.0150313984872246 CD7 other 1 1 1 -0.0377109621269138 2.43965119036544 1.30491945846574e-16 595.597281641743 71.0482472060636 8.38299754129489 4.60435042057123e-16 146.053868111888 162.821906887815 0.897016076666637 0.370114557207668 CNP other 1.41649007216457e-12 1 5.99808729287814e-12 8.38299754129489 0.897016076666637 1.32396840724841e-37 2373.85106219288 249.995595634081 9.49557153665817 7.10597707513632e-20 -3713.85615081262 618.933511133372 -6.00041213475728 3.61798025142956e-09 JUP other 1.91750344421787e-33 5.00402848575223e-05 9.75934891499223e-16 9.49557153665817 -6.00041213475728 0.00321602219320029 8.92956223225552 2.85084229370443 3.13225401909283 0.00182890319475521 -0.462503273589937 7.26908218362633 -0.0636260894988544 0.949291545938117 HAP1 other 1 1 1 3.13225401909283 -0.0636260894988544 0.0227599969167095 45.2828674299572 21.8087817476934 2.07635932872529 0.038332293158923 215.344651057209 96.5064425089809 2.23140181586498 0.0260634366070719 TDRD12 other 1 1 1 2.07635932872529 2.23140181586498 1.61393791054995e-35 1538.26039174068 157.29723318587 9.77932262751877 6.56192853021901e-21 -2155.23188950698 407.253822210489 -5.29210966715751 1.75861617131935e-07 EIF1 essential 2.31099769411647e-31 0.00230150098340563 9.10139487141376e-17 9.77932262751877 -5.29210966715751 2.16135422576902e-21 78.1991087840592 12.1474300640129 6.43750228418488 2.68097549333107e-10 -239.638711198265 35.9607811970413 -6.66389058361116 6.58109164633445e-11 ENDOV other 2.63058422818347e-17 9.43399487502043e-07 3.04800103836809e-06 6.43750228418488 -6.66389058361116 1.06008047438477e-15 1795.72192092269 224.282040306066 8.00653462253226 7.23561920198915e-15 -1075.71798069253 664.898361258722 -1.61786829893232 0.1062727579433 RNF213 other 1.12008102923494e-11 1 9.23192653981796e-11 8.00653462253226 -1.61786829893232 0.00156325569913003 6.37213892572811 1.83574345387276 3.47114893003442 0.000561346432958223 1.12475871156475 4.58571585026333 0.245274401705495 0.806340737958318 TIGD3 other 1 1 1 3.47114893003442 0.245274401705495 4.75025745126385e-11 10.8610891000763 1.66767508835296 6.5127129234766 1.76261268777381e-10 -9.87498953619827 6.39164658785887 -1.54498365960285 0.122966849473408 MARCH10 other 4.16455070752301e-07 1 2.01554760846935e-06 6.5127129234766 -1.54498365960285 0.000466741760086142 -3.96463351472107 17.4599620127919 -0.227069996590852 0.820454619082454 -139.998571491032 36.8446964578149 -3.79969398448762 0.000161226021965049 PLK3 other 1 1 1 -0.227069996590852 -3.79969398448762 1.02028038818507e-07 697.78142919928 128.330499441525 5.43737795953356 8.17253957071321e-08 -564.574990334772 551.521901897191 -1.02366739814444 0.306446550182588 NET1 other 0.000737560692618987 1 0.000839564990099368 5.43737795953356 -1.02366739814444 0.0101940831221765 34.7223614644259 22.2077928112066 1.56352149714329 0.118511493900559 -178.335670438588 84.0040888170676 -2.12294035861686 0.0342097811904979 DPY19L1 other 1 1 1 1.56352149714329 -2.12294035861686 6.290322232887e-25 121.057663816908 15.2390078846192 7.94393340652394 1.1528221362667e-14 -252.084934323722 47.7149156200145 -5.28314744033587 1.8473954813739e-07 ZNF791 other 8.12080600265712e-21 0.00241546959189637 1.46581334626311e-10 7.94393340652394 -5.28314744033587 0.000451467579401566 112.237502338391 41.3290580268545 2.71570434209903 0.00682732333381492 -501.96118216109 177.690012440341 -2.82492625931704 0.00490567864686809 PHC3 other 1 1 1 2.71570434209903 -2.82492625931704 0.00391691620909053 25.4894623090765 49.0514806608551 0.519647153677422 0.603524450230044 -695.200311065501 210.891770220872 -3.29647909132443 0.00104400402185766 GPR160 other 1 1 1 0.519647153677422 -3.29647909132443 1.95028748890672e-24 278.361739974338 36.3181818914192 7.66452849447583 8.50048546990007e-14 939.277786625752 103.020776872805 9.11736268292209 1.54757141448374e-18 CBX2 other 2.49968347453175e-20 2.37196270697923e-14 1.06018054780594e-09 7.66452849447583 9.11736268292209 7.47050952340311e-08 404.016500521553 70.6644610221915 5.71739308100964 1.83795478155946e-08 116.391258690938 262.632325767713 0.443171869078604 0.657828251279813 SPTBN2 other 0.000545272490113193 1 0.000194676170462778 5.71739308100964 0.443171869078604 0.0170285379145894 98.0707246091985 36.7219749901563 2.67062772728012 0.00779920141663028 -154.257009798838 152.73377256387 -1.00997315269176 0.312960482141032 GOLIM4 other 1 1 1 2.67062772728012 -1.00997315269176 4.01446972738278e-32 114.935172725964 10.3778450380872 11.0750519307377 1.05609907090794e-25 -131.106918921468 37.4465913169545 -3.50117098274062 0.000503689356984751 RBM4B other 5.60219250456266e-28 1 1.51877607387271e-21 11.0750519307377 -3.50117098274062 1.32585602014911e-13 159.062638409862 35.807005225381 4.44222121924661 1.08561317846153e-05 -742.495854560213 139.399334164946 -5.32639455567016 1.48633172748124e-07 HOXB2 other 1.29867597173606e-09 0.00195274262356486 0.0975206318211993 4.44222121924661 -5.32639455567016 0.0191078983995223 46.1999950001701 38.0205353040452 1.21513268108181 0.224846512190152 293.155274702183 107.467039275797 2.72786220479979 0.00658214293344343 C1QTNF1 other 1 1 1 1.21513268108181 2.72786220479979 0.0849297645820886 21.410074369918 12.0006629318085 1.78407430419276 0.0749668196849393 53.2283446542828 27.8192133295397 1.91336627760651 0.0562238373174781 MARCH3 other 1 1 1 1.78407430419276 1.91336627760651 1.59122382317706e-22 23.695223704249 3.08981991725007 7.66880411766445 8.11698436852376e-14 -50.6834725504454 10.3810382658694 -4.8823124674419 1.38218848725337e-06 SWSAP1 other 1.97932331364994e-18 0.0174390721436758 1.01283730950439e-09 7.66880411766445 -4.8823124674419 0.10143896470422 -3.7533677367468 6.86909947902283 -0.546413361490689 0.585005036409789 25.699470917201 15.270352005412 1.68296519347379 0.0929534967583831 SLCO4C1 other 1 1 1 -0.546413361490689 1.68296519347379 3.12261222995259e-27 401.34136283464 40.4805425127784 9.91442648546396 2.61395294819627e-21 -499.864292437414 144.956607351531 -3.44837190639544 0.000610545940404288 RBM4 other 4.15526009439792e-23 1 3.63548576035137e-17 9.91442648546396 -3.44837190639544 0.000181447187472723 48.6579791358088 19.4333027624531 2.50384506074904 0.0125763761868896 -87.3706140578857 43.786763673502 -1.99536587607544 0.0465003415145844 PIFO other 0.952960628606741 1 1 2.50384506074904 -1.99536587607544 5.63659277079653e-23 111.234853840983 10.5733759602766 10.5202779376127 1.07808245083359e-23 48.7119696694915 49.5239891598759 0.983603512072441 0.325746145375316 XXYLT1 other 7.06152342325389e-19 1 1.53120050491894e-19 10.5202779376127 0.983603512072441 8.93569878895383e-19 162.160389541098 17.4797169942774 9.2770603548208 4.15455022863227e-19 27.1468986039166 50.3465974836812 0.539200262991271 0.589970503090656 UBXN2A other 1.02742664675391e-14 1 5.65600468125997e-15 9.2770603548208 0.539200262991271 0.287127876757698 11.2413955169957 21.8348080451064 0.514838302849891 0.606891274209202 667.66723729518 429.003859406025 1.55631988537258 0.120258489875805 TCAP other 1 1 1 0.514838302849891 1.55631988537258 1.47404623102209e-10 181.489339665059 28.3448420897088 6.40290530074791 3.45253685822193e-10 -71.2132995518016 101.011463083962 -0.705002158939209 0.481129475556495 CCS other 1.26193097837801e-06 1 3.91379578248038e-06 6.40290530074791 -0.705002158939209 0.74103986860192 0.693083708230598 4.14539439764844 0.167193671276191 0.867280721176651 13.9994231506885 18.4367892120521 0.759320019862087 0.447994946512643 NRROS other 1 1 1 0.167193671276191 0.759320019862087 1.74163636302113e-16 18.4854957732229 2.23348220717838 8.27653594634012 1.01310552691765e-15 -28.5229768448416 9.9334916566626 -2.87139485597802 0.0042482928905126 CEP19 other 1.88305723569845e-12 1 1.31136379404221e-11 8.27653594634012 -2.87139485597802 7.47338602518727e-40 258.621959913739 17.7220199686654 14.5932551916211 7.39597989696192e-41 -63.8067351019222 78.8193149388658 -0.809531713786301 0.418568587238659 FBXO45 other 1.09410371408742e-35 1 1.11967739660106e-36 14.5932551916211 -0.809531713786301 2.85119794152152e-11 402.557179668534 71.7302369977974 5.61209883749437 3.19054861111636e-08 -211.447747358978 136.219866775888 -1.55225337069853 0.121184227980312 GNG5 other 2.52815721474713e-07 1 0.000334273777986661 5.61209883749437 -1.55225337069853 1.06750671077518e-10 30.8300698860273 18.0511139229723 1.70793171089526 0.0882216249486762 -169.106931186026 34.50518005591 -4.90091432393676 1.26194008281168e-06 SLC25A30 other 9.19230028648509e-07 0.0159496607066568 1 1.70793171089526 -4.90091432393676 0.0348141574135828 2.33052764927637 49.4375874825225 0.0471408045568621 0.962418499567195 -981.944488422213 378.004017041672 -2.59770913575758 0.0096418326895364 CD34 other 1 1 1 0.0471408045568621 -2.59770913575758 5.69639601125261e-05 384.421576265267 101.986147974392 3.76935087656996 0.000182733397647715 -461.270092163132 358.403305659082 -1.28701405617586 0.198670928846734 CTSF other 0.319681744151497 1 1 3.76935087656996 -1.28701405617586 0.559471593884287 -6.62371291961162 39.1075606163587 -0.169371671748836 0.865569668069969 -188.986750085807 175.259867411228 -1.07832302327589 0.281385759830159 MSRB3 other 1 1 1 -0.169371671748836 -1.07832302327589 2.50551202120687e-32 196.414773555907 15.4556772893672 12.708260523208 1.89209408406575e-32 -37.2810573543141 68.8334903552956 -0.541612188512912 0.58831546231747 LEMD3 other 3.50095194723237e-28 1 2.80578631726111e-28 12.708260523208 -0.541612188512912 1.03573436485922e-23 81.1692346446601 7.91179994493235 10.2592627732771 1.09136852262005e-22 5.97726934148085 35.8846090062733 0.166569164524989 0.867771178153401 C16orf91 other 1.31268973402258e-19 1 1.53653774299677e-18 10.2592627732771 0.166569164524989 0.000506525586088129 -13.6407824351134 3.62957808644525 -3.75822812190078 0.000189479951732387 -20.3810811326357 7.15262575548437 -2.8494544282578 0.00454412414532371 TLR10 other 1 1 1 -3.75822812190078 -2.8494544282578 0.0539496594748685 13.1803424055827 19.4636758800892 0.677176422726288 0.498579787061311 90.2893290054892 38.3560805362564 2.35397693776721 0.0189258345143605 TLR1 other 1 1 1 0.677176422726288 2.35397693776721 0.0861291240648038 4.40536519275268 14.188525590476 0.310487877310505 0.756308028900347 57.5819969500248 27.9606089616275 2.05939709786182 0.0399280696078336 TLR6 other 1 1 1 0.310487877310505 2.05939709786182 2.7895049359303e-41 74.5659178457609 17.8177212326256 4.18493009696578 3.3249985703223e-05 -455.170425464388 39.5494963565369 -11.5088804509935 1.37398650418066e-27 FAM174A other 4.10726706766377e-37 2.14616691953019e-23 0.287246626490144 4.18493009696578 -11.5088804509935 4.34225896827286e-14 75.5969860671343 26.3118995371686 2.87311016676484 0.00422296134909593 -354.440666125397 60.8778445942551 -5.82216187987123 9.92870149023228e-09 RGMB other 4.32879796547121e-10 0.000135774992878926 1 2.87311016676484 -5.82216187987123 1.47787665695547e-31 26.5867004082936 2.34176790532472 11.3532602218353 6.35951455309353e-27 -5.44229477083757 6.07028633455111 -0.896546632382213 0.370362619166779 FAM53A other 2.05173616285127e-27 1 9.20921302433474e-23 11.3532602218353 -0.896546632382213 5.01979715015175e-08 32.9656008394145 14.6214508604169 2.25460531612897 0.0245594477234186 -132.923796098654 32.9399459564116 -4.03533740688426 6.24288417188258e-05 CYB561D1 other 0.000371715978968737 0.714747808838836 1 2.25460531612897 -4.03533740688426 3.63321788034156e-18 139.221747519294 17.5675178520292 7.92495267071623 1.40316632556516e-14 -162.323692707512 60.9920738972076 -2.66138995340744 0.00802300062201457 ZDHHC24 other 4.11716250200305e-14 1 1.78103901703986e-10 7.92495267071623 -2.66138995340744 3.24451287465132e-13 121.650547271666 16.9145124981516 7.19208119565726 2.14487011745637e-12 -120.025006357981 58.8861939531464 -2.03825376205295 0.0420121538659249 TRMT10C other 3.1273859598764e-09 1 2.58842925774635e-08 7.19208119565726 -2.03825376205295 0.0964100703544704 -12.339638894279 8.2281965090445 -1.49967722340068 0.134277068974237 -103.673107049995 61.9659550292284 -1.67306558901729 0.0948882394466606 SELP other 1 1 1 -1.49967722340068 -1.67306558901729 4.20037979034508e-34 63.1825753766011 11.535463594846 5.47724630719053 6.67244718824641e-08 -149.311809086149 24.8083852263812 -6.01860248958772 3.27867637826747e-09 CTU2 essential 5.95319827685609e-30 4.53867171043566e-05 0.000688729998770794 5.47724630719053 -6.01860248958772 0.12354772953659 39.9397236562955 52.4082855830833 0.762087963991471 0.446340230572904 -113.740660527001 88.7158474025534 -1.28207827414301 0.200365329949541 MGA other 1 1 1 0.762087963991471 -1.28207827414301 2.09454827347841e-21 70.9815133010885 9.19230013399412 7.72184461629915 5.85853425237503e-14 -141.372212870093 28.4807570200842 -4.96378002770078 9.36472536467398e-07 C12orf66 other 2.55011252295997e-17 0.0119109941913288 7.33605659082401e-10 7.72184461629915 -4.96378002770078 3.84198931519939e-34 141.621581066093 25.5506734865527 5.54277291910245 4.82070521051098e-08 -483.167242632298 56.4878348392278 -8.55347428357734 1.46113740625562e-16 PIGG other 5.44717245108969e-30 2.21683767277103e-12 0.000501112306632617 5.54277291910245 -8.55347428357734 3.84828902986592e-33 1720.9994073244 206.345574224944 8.34037470291599 6.15494366359767e-16 -2207.59822277268 379.210314761365 -5.82156691640076 9.99046667527093e-09 PRPF8 essential 5.41608198063329e-29 0.000136589660384304 8.00327324577605e-12 8.34037470291599 -5.82156691640076 5.84861058406324e-15 273.6969066349 72.468014247405 3.7767960041033 0.000176367292945649 -1338.0786053681 216.079539900691 -6.19252801992766 1.16785498841808e-09 ADCY6 other 6.0293326511108e-11 1.63347877230037e-05 1 3.7767960041033 -6.19252801992766 1.60303190685356e-06 3.13835538587081 0.619717309922293 5.06417254387219 5.64080179904311e-07 -1.61832595010492 3.47056786704374 -0.466300044287399 0.641189140618185 REP15 other 0.0105062711175182 1 0.0055082429567656 5.06417254387219 -0.466300044287399 1.232164691592e-35 474.649205568496 52.076429261284 9.11447294489087 1.53651094909924e-18 -530.679501495837 95.5922542626791 -5.55149060547915 4.44331890497939e-08 PITPNA other 1.76630808539713e-31 0.00059509370094389 2.07920661632109e-14 9.11447294489087 -5.55149060547915 3.98662963329965e-15 431.800347160666 62.5663805622301 6.90147557331029 1.43729875874285e-11 -523.201265476475 186.195102262938 -2.80996255603774 0.00513309060304766 DDX23 essential 4.13214161491509e-11 1 1.69744983407531e-07 6.90147557331029 -2.80996255603774 1.09091375733497e-05 29.2805190072759 16.1474610053689 1.81332031070027 0.0703565957053527 -134.282797498419 39.0662686265096 -3.43730799535069 0.000634411969676381 ZNHIT2 other 0.066142101107219 1 1 1.81332031070027 -3.43730799535069 2.3752665711959e-53 153.209713143071 80.6355599912059 1.90002665275445 0.0579581089703699 -2153.79535181347 144.936309914641 -14.8602883092714 3.59157237258674e-42 ZBTB4 other 3.61396808807456e-49 5.63086716574149e-38 1 1.90002665275445 -14.8602883092714 8.70695070052563e-46 95.6548486517935 23.6064888864213 4.05205742844778 5.82675173600741e-05 -527.997746710264 43.1138453922686 -12.2465936848432 1.39038502398964e-30 TNK1 other 1.30325638085468e-41 2.17609160104619e-26 0.492069184105826 4.05205742844778 -12.2465936848432 2.77076742962073e-11 98.1785096547895 18.0671213485862 5.43409809236005 8.44995661339117e-08 -402.741505530885 108.759001601646 -3.70306365082328 0.000235601783933117 ZHX3 other 2.45767071007359e-07 1 0.000867050048100068 5.43409809236005 -3.70306365082328 5.63588294941378e-06 161.139279109415 32.4194222306869 4.97045499339244 8.9544781192637e-07 55.9495747894709 233.679562233601 0.239428618637774 0.810863091226202 PHLDA3 other 0.0349931972329102 1 0.0086419668329014 4.97045499339244 0.239428618637774 0.0178071081569505 0.439352943268771 3.5164935568001 0.124940636509674 0.900616449299929 -16.3066355191315 6.41158495188323 -2.543308034052 0.0112550272536924 SLC16A11 other 1 1 1 0.124940636509674 -2.543308034052 9.74359011520794e-13 36.6375088537927 4.98906167152538 7.34356704045132 7.58871880255435e-13 10.2976264975164 9.09650258716169 1.13204238649368 0.258112623738594 SLC16A13 other 9.20866701788303e-09 1 9.24533611715196e-09 7.34356704045132 1.13204238649368 0.0266166584495407 -0.282944801233453 2.26049273969916 -0.125169524442316 0.900435840883926 -13.2422183776853 5.08677556861285 -2.60326373732592 0.00948752478995305 GLIS1 other 1 1 1 -0.125169524442316 -2.60326373732592 0.974572360544561 3.52960171371402 147.762120081606 0.0238870538116582 0.980951428083709 -55.8438983263338 303.907952149997 -0.183752672252457 0.854275705440673 CHRNA9 other 1 1 1 0.0238870538116582 -0.183752672252457 8.02710051201656e-07 -506.507346522017 103.397447884272 -4.89864456895423 1.27725946523772e-06 -792.017842450886 216.299262606532 -3.66167610978701 0.000275226159283887 PODN other 0.00540866032499676 1 0.0122169867849988 -4.89864456895423 -3.66167610978701 3.49532626986945e-05 27.6352532620944 8.11319659831283 3.40621023134595 0.000709382355292997 -71.3222304787195 31.1157756484527 -2.29215659877873 0.0222929415141357 TRIM74 other 0.201365746407179 1 1 3.40621023134595 -2.29215659877873 7.6562614357458e-15 50.4531856513828 6.94900670456721 7.26048884342314 1.373555328372e-12 -151.388344097927 49.6103710924902 -3.0515462949408 0.00239008877278508 SNHG11 other 7.86068361608021e-11 1 1.66474905798686e-08 7.26048884342314 -3.0515462949408 5.03741424919263e-06 15.5100997312474 3.15217689351871 4.92044077955719 1.14836376421328e-06 12.7573004025562 6.02017802306924 2.11909022518444 0.0345386475832415 C11orf45 other 0.0314233900864636 1 0.0110116601350411 4.92044077955719 2.11909022518444 2.53991475679888e-10 78.2029343774487 12.392844639977 6.31032960142021 5.80734202355108e-10 223.321183207848 76.9255520922564 2.90308196865484 0.00384613975102551 EXO1 other 2.14978385015458e-06 1 6.525129497662e-06 6.31032960142021 2.90308196865484 7.9472733130309e-26 70.2822036972233 15.9479358430953 4.40697808096915 1.26973420668325e-05 -373.863806843088 41.8037457999546 -8.9433087798437 6.33229487606954e-18 RALGAPA1 other 1.03918545841192e-21 9.67891271807229e-14 0.113450751367148 4.40697808096915 -8.9433087798437 2.26007231513718e-24 62.3251374429765 7.38627691122332 8.43796383375154 3.00910511717682e-16 -64.2125940655822 17.4106397155865 -3.68812376308594 0.000248907492202443 LIG4 other 2.89357058507013e-20 1 3.93320129866182e-12 8.43796383375154 -3.68812376308594 2.25013060711292e-08 8.33267747993866 15.0465553132823 0.553793031457707 0.579967078066992 -326.597714972508 57.1862173702213 -5.7111263865929 1.92397103353183e-08 GTF2IRD2B other 0.000170537398713088 0.000260601876491887 1 0.553793031457707 -5.7111263865929 0.00334847387150698 1233.71183915623 364.571304516996 3.38400697989853 0.000766230187122906 1060.88477936433 818.538369591088 1.29607214368497 0.195504289465075 ATP2A2 essential 1 1 1 3.38400697989853 1.29607214368497 5.08281162386581e-13 136.044904240333 17.7606920733686 7.65988755834166 8.68796834550559e-14 124.778094206648 40.8851621456341 3.05191633488416 0.00238591738806452 ZWILCH other 4.85357681962946e-09 1 1.08338965268455e-09 7.65988755834166 3.05191633488416 5.10708604816536e-12 3967.92617362512 585.088127017193 6.78175814958644 3.13464843555577e-11 -1328.51371189511 1346.59944543312 -0.986569329432487 0.324297287050855 RPL4 essential 4.69392278686878e-08 1 3.66409055632114e-07 6.78175814958644 -0.986569329432487 3.47550183331697e-55 139.795108615266 8.80679100401901 15.8735580930068 8.05343636331894e-47 -73.1752202456294 20.2691173080476 -3.61018287740513 0.000334585688108772 SNAPC5 essential 5.30118294635838e-51 1 1.22959866395154e-42 15.8735580930068 -3.61018287740513 1.71224795897707e-23 6.54693551396456 7.33396598812263 0.892686920633029 0.372423964471471 -163.941755824887 16.4424784225599 -9.97062313914617 1.33885160281608e-21 C12orf76 other 2.16256917218804e-19 2.0717389701976e-17 1 0.892686920633029 -9.97062313914617 0.140826304508668 79.0547926521509 124.966917890287 0.632605764683707 0.527259888153093 -621.351744521043 395.479583317083 -1.57113482144757 0.116739235132145 CNTNAP2 other 1 1 1 0.632605764683707 -1.57113482144757 0.00320807414862639 -5.53357939683637 4.22016809877867 -1.31122250756736 0.190338843947625 -31.0500984354473 9.11953872450362 -3.40478826544348 0.000711275655739084 GALNTL6 other 1 1 1 -1.31122250756736 -3.40478826544348 2.77450438624608e-19 221.493581902935 29.930752939511 7.40020080184972 5.48725671152145e-13 -415.34362536881 103.312859849041 -4.02025097336093 6.67236529082853e-05 BBS1 other 3.23423976304705e-15 0.761917392559709 6.70926878117727e-09 7.40020080184972 -4.02025097336093 9.66754249283125e-30 220.13703088729 21.225108953649 10.3715383213354 4.1737334065012e-23 -178.906197899242 48.4829261717578 -3.69008663514742 0.000246911021708037 DENND4A other 1.32000625197118e-25 1 5.89748530338619e-19 10.3715383213354 -3.69008663514742 3.97373061419446e-07 68.7652155112522 14.4113045584082 4.7716162844627 2.3565361503792e-06 -45.0426861421572 32.7952526596956 -1.37345141412841 0.170183055994011 IGDCC3 other 0.00274584785440837 1 0.0221891443919706 4.7716162844627 -1.37345141412841 3.01924631790811e-06 -11.758737441336 3.05306245236225 -3.85145657018509 0.000131368730274373 -39.6726103250995 10.2400710212706 -3.874251481527 0.000119960759761826 GCSAM other 0.0192839262324791 1 1 -3.85145657018509 -3.874251481527 0.461428988878126 0.691078229381332 7.62441534744153 0.0906401603125192 0.927813490079209 38.6748639755441 31.3094474736947 1.23524581543758 0.217297909091622 ANKRD36C other 1 1 1 0.0906401603125192 1.23524581543758 0.212287589258966 -6.41389551026231 6.11895871112482 -1.0482004885245 0.295016029950999 80.8719253392608 56.03191918016 1.44331885329918 0.149511589064534 SLC26A9 other 1 1 1 -1.0482004885245 1.44331885329918 1.63249643531268e-06 1.66893280963876 9.63542562721149 0.17320800078883 0.862552599963233 458.848451615946 88.0680360288426 5.21015878525635 2.68562401517052e-07 MFSD4A other 0.0106928516512981 0.00348979778087604 1 0.17320800078883 5.21015878525635 2.70433207112776e-20 91.2351927818828 10.2466737444374 8.90388384146723 9.01477207999243e-18 -65.9194347931075 34.9810341185241 -1.88443356390657 0.0600638667171628 PELI3 other 3.2216707963345e-16 1 1.20797945871899e-13 8.90388384146723 -1.88443356390657 2.30286421583584e-19 9.75972967846379 1.06668488365406 9.14959031296159 1.15998616601901e-18 25.7412580639267 9.70994785982612 2.6510191852243 0.00826007024269067 TMEM81 other 2.69135740904734e-15 1 1.57189725357236e-14 9.14959031296159 2.6510191852243 1.30444031139425e-15 190.81608223441 24.3958667828285 7.82165618188729 2.92554497661799e-14 -100.847894097736 80.0641527271144 -1.2595886006745 0.20838286084853 MRPL11 other 1.37396697999157e-11 1 3.68852710651996e-10 7.82165618188729 -1.2595886006745 0.623016005684067 20.5478633505253 21.4685884064192 0.957112920585939 0.338936193197936 25.7684649087271 77.0976822183346 0.334231382413713 0.738334012842444 IL20RB other 1 1 1 0.957112920585939 0.334231382413713 9.17083733311590e-09 29.6351635691026 4.8036648045968 6.16928215739442 1.34649262053297e-09 9.77019618699291 40.3566963152784 0.24209603557896 0.808797663192241 GOLT1A other 7.11015018436475e-05 1 1.49070198019205e-05 6.16928215739442 0.24209603557896 7.10420320209229e-16 273.499758803306 40.4917506245692 6.75445626787385 3.73611406871274e-11 -247.440550467024 86.3194752128061 -2.86656689996088 0.0043123185506584 AKIRIN1 other 7.54679506158264e-12 1 4.35556178130531e-07 6.75445626787385 -2.86656689996088 6.6819207833682e-14 114.408788194883 19.7580217788491 5.79049813161746 1.18850459369741e-08 -314.02478902397 69.932315076431 -4.49041031575694 8.68755567451526e-06 MSL2 other 6.61911072800454e-10 0.105310549886474 0.000126860980331261 5.79049813161746 -4.49041031575694 2.56553490484233e-14 42.7027589871973 7.16876437791836 5.95678093685612 4.83748244222937e-09 -111.876297510466 26.6016975813225 -4.20560744924101 3.08284305366973e-05 ZNF497 other 2.58041500729042e-10 0.360322696112918 5.2409284779113e-05 5.95678093685612 -4.20560744924101 6.77158713285019e-17 16.7120649645186 7.80642451537634 2.14080914144508 0.0327349041425025 -115.011462614572 16.4225015026745 -7.00328525443226 7.43484627000155e-12 TRAM1L1 other 7.41353359304438e-13 1.08162143535983e-07 1 2.14080914144508 -7.00328525443226 0.477052719314901 -17.1652636532216 21.7830441037209 -0.788010324520689 0.431032010609301 32.3701674040043 50.3065650227681 0.643458113058484 0.520196551041474 CMKLR1 other 1 1 1 -0.788010324520689 0.643458113058484 8.61282388861698e-19 139.272368714786 15.5896131378352 8.93366419573162 6.70101434277921e-18 -191.549086260347 97.625457890003 -1.96208130953066 0.0502729412790683 ANGEL2 other 9.90819260146498e-15 1 9.00080246522104e-14 8.93366419573162 -1.96208130953066 1.46129494624138e-12 220.224292760394 36.6192183840199 6.01389932605709 3.33226270053094e-09 535.222435367315 79.997182376985 6.69051608399269 5.55569797108145e-11 UGT8 other 1.3724482135099e-08 7.9740932978932e-07 3.63216634357873e-05 6.01389932605709 6.69051608399269 2.89147475133364e-13 119.206384894052 16.7067075277201 7.13524102198246 3.08826547762427e-12 -105.023355636413 90.7230957247727 -1.15762535214873 0.247523106944586 IQCK other 2.79432119968883e-09 1 3.7127127571999e-08 7.13524102198246 -1.15762535214873 0.00148721458906999 -49.0011837097935 26.5195728724101 -1.84773653578608 0.0651821318700812 -314.930297902883 92.8609591550721 -3.39141767184387 0.000745752444496971 SLCO2A1 other 1 1 1 -1.84773653578608 -3.39141767184387 1.22107782392147e-29 158.44302629547 15.0494293877922 10.5281750033656 1.12104270177246e-23 -199.210226246317 56.4199380255308 -3.53084801610685 0.000450106359693682 ZNF266 other 1.66555015182889e-25 1 1.59199274078707e-19 10.5281750033656 -3.53084801610685 1.1232917283237e-21 155.220534489685 17.2337871467097 9.00675708527131 3.9780003691108e-18 -131.647795937837 55.8435305036429 -2.35744041880105 0.0187695340822371 SLC29A2 other 1.37490907546821e-17 1 5.35558189693387e-14 9.00675708527131 -2.35744041880105 0.0317957035934432 29.3178855206478 12.3288312985342 2.37799389177573 0.0177515609695617 4.2502913970493 24.4908424865998 0.173546148907488 0.862286713227595 BRSK2 other 1 1 1 2.37799389177573 0.173546148907488 5.73152377748279e-22 177.193774494876 18.8371266708959 9.40662435363073 1.5969328059985e-19 -99.4843748747707 60.5842371537956 -1.64208347828537 0.10117266573406 B4GAT1 other 7.05837153197005e-18 1 2.18556223828955e-15 9.40662435363073 -1.64208347828537 5.76406897312402e-10 216.972707578822 62.459547217449 3.47381172686772 0.000553996999576713 -546.081507869112 142.061556600768 -3.84397806792834 0.000135356847781053 TMEM167A other 4.78360084079562e-06 1 1 3.47381172686772 -3.84397806792834 0.0688012671789725 334.294232488738 152.328552554024 2.19456055272487 0.0286178891319239 743.496218700978 546.103720243122 1.3614560588783 0.173934253951218 LEP other 1 1 1 2.19456055272487 1.3614560588783 0.0169191377571692 -49.7409567888922 79.4720530298963 -0.625892435044812 0.531650926086494 510.623955720474 212.423616971075 2.4038003071476 0.0165628640002091 SH3PXD2B other 1 1 1 -0.625892435044812 2.4038003071476 0.00634899188201907 61.9245596416998 47.4097281791595 1.30615723860912 0.192083293125987 -620.644334530629 232.745724301778 -2.66661970436845 0.00790326622558009 KIAA1551 other 1 1 1 1.30615723860912 -2.66661970436845 7.29383002724755e-28 164.185107384245 25.178437661255 6.52086160361313 1.59185605093502e-10 -333.202854839861 54.58187821945 -6.10464252439604 1.9537346455475e-09 LARP7 other 9.77373223651171e-24 2.71940325313757e-05 1.82140169347985e-06 6.52086160361313 -6.10464252439604 0.183205385238366 26.2801243393949 16.8624263638022 1.55850194820179 0.119697993599884 -10.600938068712 32.3037600250022 -0.328164215574507 0.742914237837636 FGFBP3 other 1 1 1 1.55850194820179 -0.328164215574507 0.000353672796742106 120.733071004423 51.0374828085073 2.36557652064099 0.0183556640889023 -245.116267780813 108.472314510579 -2.25971270998286 0.0242382416492784 NR1D2 other 1 1 1 2.36557652064099 -2.25971270998286 3.2319665156687e-19 301.32074951311 36.2659193849202 8.30864775038358 8.33748891358577e-16 -279.57840874482 116.638970422762 -2.3969553891935 0.0168812189594829 BRMS1 other 3.75942345102583e-15 1 1.08112218742467e-11 8.30864775038358 -2.3969553891935 9.62260007014339e-21 831.358749705199 350.758818164622 2.37017205741358 0.0181314731749027 -6244.2654929297 745.483882582267 -8.37612407031567 4.77622125341711e-16 RPL15 essential 1.15692520643334e-16 7.22403464579338e-12 1 2.37017205741358 -8.37612407031567 1.86369061920113e-06 161.891610016545 43.8133258839752 3.69503128900236 0.000242229221528989 -104.847486374563 90.0316867197536 -1.16456205803328 0.24470958074478 HRAS og 0.0121549902184297 1 1 3.69503128900236 -1.16456205803328 9.13186763844765e-24 757.004761480936 86.0994308277827 8.79221563026483 2.00740326401031e-17 -601.324759001327 211.141672200645 -2.84796815680183 0.00456913399064362 SRP72 essential 1.15801213523155e-19 1 2.67546707027295e-13 8.79221563026483 -2.84796815680183 8.31535565551533e-38 137.737406770803 9.97607720310936 13.8067703333203 2.04416310065466e-37 20.7979828747117 36.0702109397891 0.576597206748504 0.564448775676478 PCP2 other 1.20547710938006e-33 1 3.0715594750437e-33 13.8067703333203 0.576597206748504 0.00486161838151383 29.291618745542 11.677671994928 2.50834402252987 0.0124308568293348 -50.7779697405647 37.5578962707748 -1.35199185211225 0.176961171274692 RIN1 other 1 1 1 2.50834402252987 -1.35199185211225 6.43536036221632e-25 45.6100657176229 8.32721173920716 5.47723141263194 6.64183080493747e-08 -178.195250829059 24.4944982707888 -7.27490920038841 1.23260974129777e-12 THAP6 other 8.30740669158505e-21 1.80910131730273e-08 0.000685702612301744 5.47723141263194 -7.27490920038841 7.01048559920863e-11 58.2698254979628 10.252228271675 5.68362544745044 2.17129012125027e-08 -45.6979904324611 25.0611159919015 -1.82346190996556 0.0687923274328913 CEP135 other 6.09701932563175e-07 1 0.000229223098100391 5.68362544745044 -1.82346190996556 0.00210375634470451 6.64768664875398 109.234654535957 0.0608569384596326 0.951496347610298 -756.105306803908 247.725742405401 -3.05218706567261 0.0023870525647624 FZD4 other 1 1 1 0.0608569384596326 -3.05218706567261 0.298692849428473 -14.368903811311 59.1993081458437 -0.242720806397123 0.808316664410728 -287.488503425749 186.151405124003 -1.5443799805553 0.123099994312846 CD248 other 1 1 1 -0.242720806397123 -1.5443799805553 1.86383211344186e-12 38.8955977873076 5.19604036381025 7.48562271729267 2.92888612547663e-13 26.184891114528 15.9565732558988 1.64100967636319 0.101379846789461 BTC other 1.74286940927948e-08 1 3.60897348381231e-09 7.48562271729267 1.64100967636319 0.471424176327042 -1.70211712009173 2.10252241649268 -0.809559558908826 0.418545370494998 -6.56196154067039 5.78342513780368 -1.13461510857602 0.257033575584856 ADGRE1 other 1 1 1 -0.809559558908826 -1.13461510857602 2.33252205841596e-20 90.9685387478452 23.4177739952792 3.88459376054204 0.000115196680111507 -272.644241534781 44.0757726323343 -6.18580742325473 1.2196669058642e-09 DENND6A other 2.78106605024934e-16 1.70533826777933e-05 0.945995137075697 3.88459376054204 -6.18580742325473 8.97484307478925e-32 101.688830802593 23.1882395295796 4.3853622726674 1.39107240024362e-05 -368.799209472081 43.4052709073352 -8.49664572441955 1.88522307112883e-16 PDE12 other 1.24840067170318e-27 2.85837522044554e-12 0.123902818689699 4.3853622726674 -8.49664572441955 1.13714123366985e-09 52.5943603852228 9.83813122823192 5.34597060814718 1.3311440138932e-07 -24.4475584662513 18.7322660652576 -1.30510416524532 0.192415283851106 GLMN essential 9.27679818427866e-06 1 0.00134911445808076 5.34597060814718 -1.30510416524532 0.000116127807326075 1.16855942024561 2.47487813474605 0.472168469162023 0.636996236698762 -16.3636909175542 4.63263956559795 -3.53226075239508 0.000447088061790271 DNAH12 other 0.625928881487543 1 1 0.472168469162023 -3.53226075239508 1.86953843219816e-17 367.181756884094 43.3063952683013 8.4786959202965 2.31919743239546e-16 -101.13506318701 128.350187878966 -0.787961941141686 0.431074585059485 YIF1A other 2.07855282891792e-13 1 3.03814863643806e-12 8.4786959202965 -0.787961941141686 0.000921354330109999 40.8863884934548 11.0654975615559 3.69494351844634 0.000242970204736488 11.8566681500726 32.7969067295525 0.361517878739121 0.717857511435876 CNIH2 other 1 1 1 3.69494351844634 0.361517878739121 0.476541123954419 -0.25859963824745 7.84239413052593 -0.0329745781636847 0.973707440552491 -16.7023596739417 15.0106465410917 -1.11270088388391 0.266348086783711 AMY1B other 1 1 1 -0.0329745781636847 -1.11270088388391 0.00291399562508267 -0.389324045134934 2.35140791918675 -0.165570610678892 0.868557074446035 -14.4907660490166 4.817996536846 -3.00763313925143 0.002756032583972 NLRP6 other 1 1 1 -0.165570610678892 -3.00763313925143 1.3391330902422e-13 578.405495812854 81.4356290940217 7.10260978207775 3.85803323637581e-12 -158.868947892494 193.92141306518 -0.819243967859782 0.413006651642767 NDUFA11 other 1.31141303527418e-09 1 4.62809667035642e-08 7.10260978207775 -0.819243967859782 9.68883971203282e-21 133.798453154889 13.5531378166027 9.87213846456906 3.14620854590287e-21 -74.8212996284055 52.3714546363847 -1.42866567575582 0.153683902668982 RSRC1 other 1.16469542178346e-16 1 4.37354449965958e-17 9.87213846456906 -1.42866567575582 7.36966592614999e-05 10.9094171547268 2.80140394664675 3.89426778947222 0.000110911625502328 23.7894130764535 10.9477182135572 2.17300195459851 0.0302166182947968 PQLC2L other 0.40783731235314 1 0.912580854633155 3.89426778947222 2.17300195459851 3.18932139711382e-27 1527.51387478284 158.748275366873 9.622239178679 2.69069637088664e-20 -1692.32183772843 462.415642180697 -3.65974176337902 0.000277941899462347 RAB1B other 4.24339211885994e-23 1 3.71100843472686e-16 9.622239178679 -3.65974176337902 1.19858328157431e-11 74.721434198636 25.4033205980617 2.94140421171307 0.00340718798345096 -213.876930322704 52.1659903070518 -4.09993041565612 4.76767566010994e-05 PTDSS2 other 1.08184126994897e-07 0.551000276038905 1 2.94140421171307 -4.09993041565612 1.54834894095951e-11 190.920530949521 36.8288063697509 5.18399996548171 3.06874531430002e-07 -249.220632452467 87.2509480990829 -2.85636589495223 0.0044493119843034 C19orf70 other 1.38917866982887e-07 1 0.00305039983498076 5.18399996548171 -2.85636589495223 0.000528684305412817 12.7585739366865 3.61428672032731 3.53003923704512 0.000450773311554809 -21.5126396274902 13.8984940744387 -1.54783960854112 0.122243516219213 C3orf33 other 1 1 1 3.53003923704512 -1.54783960854112 2.0262246033458e-05 235.174386496146 75.6500743754174 3.10871322252879 0.00197937606272291 -1251.62239459784 467.104800905638 -2.67953228519843 0.00760043639004847 SEZ6L2 other 0.119729611811704 1 1 3.10871322252879 -2.67953228519843 0.397468906773302 10.2522709989184 8.35695288764923 1.22679535672269 0.220441150458532 -14.3069952227327 51.6003830398303 -0.277265291067494 0.78168390985257 ASPHD1 other 1 1 1 1.22679535672269 -0.277265291067494 1.59949615855127e-23 116.763567890624 11.962441809231 9.76084730464658 8.12034734338835e-21 -155.282954187927 73.8626372251375 -2.10232074052021 0.0359936774624974 KCTD13 other 2.02192309402466e-19 1 1.12548014179363e-16 9.76084730464658 -2.10232074052021 0.427478885094908 -0.271880511487519 1.76234732504923 -0.15427180988851 0.877452429530747 10.8062538711479 8.33520156814832 1.29645981357455 0.195364787720486 P2RY14 other 1 1 1 -0.15427180988851 1.29645981357455 0.0292954781074644 2.71393511101037 9.6338322969593 0.281708776668965 0.778274746928473 -84.2691560343532 33.8669732308324 -2.48823995755354 0.013138076234663 AMZ1 other 1 1 1 0.281708776668965 -2.48823995755354 0.55665108166051 -0.543687559487361 1.75492521725922 -0.309806682438853 0.756826390342928 7.81145934429165 7.67144168510647 1.01825180519289 0.309010106539996 GPR171 other 1 1 1 -0.309806682438853 1.01825180519289 0.00857576807251182 5.55567902622944 3.81502170128387 1.45626406905098 0.145902955257488 -9.33805191995236 5.97123438525836 -1.56383945386668 0.118443267246967 CD164L2 other 1 1 1 1.45626406905098 -1.56383945386668 8.1393586886482e-08 41.7739744484331 7.29593318603585 5.72565200136248 1.70375635060707e-08 53.1267436184138 23.0874397214042 2.30111022527805 0.0217618950916457 FUT1 other 0.000592219738186043 1 0.00018068336098188 5.72565200136248 2.30111022527805 9.5016330568468e-20 271.746975041343 28.0687460062951 9.68147900089291 1.46098712054564e-20 -62.0650791810242 109.461099142843 -0.567005809982153 0.570943683963797 DHX36 essential 1.1200525047411e-15 1 2.01923029930613e-16 9.68147900089291 -0.567005809982153 0.0022011235746447 12.1724932359943 3.47618146596031 3.50168521269404 0.000500375791447475 7.45392283434413 12.9154677295868 0.577131466734933 0.564089843078201 ZIC4 other 1 1 1 3.50168521269404 0.577131466734933 3.68007613991508e-14 49.1228879737756 15.8896842018718 3.09149554828716 0.00209410422267211 -215.002543679951 34.8470284378062 -6.1698960662795 1.340019644485e-09 FBXW8 other 3.67970813230109e-10 1.87200744334555e-05 1 3.09149554828716 -6.1698960662795 4.36664411968091e-21 375.79078054651 39.0053875907446 9.63433012099282 2.43460897064388e-20 -28.2316231108279 113.618250715466 -0.24847788918638 0.803861656359845 KLC2 other 5.28582270687374e-17 1 3.35878653590029e-16 9.63433012099282 -0.24847788918638 1.50396119535253e-12 361.183117920341 103.37145008462 3.49403164630733 0.000514984337038649 -979.739821401823 199.037235434129 -4.9223946427153 1.13861646329228e-06 CTBP2 other 1.41176837407742e-08 0.01442171612406 1 3.49403164630733 -4.9223946427153 0.00168005565324979 44.5585427358065 13.1259516381478 3.39469045477102 0.000737267389961793 75.3980303950035 46.610870823815 1.61760613055271 0.106328226161858 CHST2 other 1 1 1 3.39469045477102 1.61760613055271 5.97420498496073e-08 15.0130437692411 8.67837562237859 1.72993707837761 0.084209741809976 -73.9791942176415 18.4013362542621 -4.02031641590737 6.6341339379549e-05 ZDHHC14 other 0.000439820970992809 0.757750778393209 1 1.72993707837761 -4.02031641590737 2.13068838682813e-12 152.537795401253 23.2009293646276 6.57464160180645 1.14175119519188e-10 -228.310433194793 83.0464066348678 -2.74919099388142 0.00617211068778226 ATR ts 1.98622771420119e-08 1 1.31347057494874e-06 6.57464160180645 -2.74919099388142 1.70031477696338e-15 1682.71215987844 481.440433523566 3.49516169126679 0.000512857358616867 -4555.00078483041 869.602129306356 -5.23802855504016 2.33297674355734e-07 LRRC75A-AS1 other 1.78397026398998e-11 0.00303706912476294 1 3.49516169126679 -5.23802855504016 1.55038254785283e-22 357.683376932133 34.8234254096646 10.2713438647786 9.97908933119145e-23 812.082611140011 228.286554745231 3.55729496222982 0.000407649901914894 UBE2C other 1.92867588952892e-18 1 1.405454941405e-18 10.2713438647786 3.55729496222982 2.47425036568642e-08 107.172575184066 21.9564198644318 4.88114983434433 1.387280654773e-06 -228.562125249901 79.127990506385 -2.88851168577898 0.00402457304063384 GK5 other 0.000186929615127609 1 0.0132318828852249 4.88114983434433 -2.88851168577898 2.61238648341161e-40 261.169147935442 18.0525206949976 14.4671845194346 3.64978936525239e-40 -219.003002339698 165.20300090289 -1.32565995256002 0.185528892866407 VCPIP1 other 3.83158725521981e-36 1 5.51775156238856e-36 14.4671845194346 -1.32565995256002 0.840678881831071 392.363468262991 771.66110677889 0.508466041395835 0.611334591244159 -283.380498129591 1709.07262518837 -0.16580951210213 0.868369033859354 DES other 1 1 1 0.508466041395835 -0.16580951210213 2.98600838052817e-13 109.876241556093 24.1920655692673 4.54182968550132 6.87328723707007e-06 -123.394000399652 40.216237782255 -3.06826314952062 0.00226030494682324 PDIK1L other 2.8838868939141e-09 1 0.0626897717840167 4.54182968550132 -3.06826314952062 2.9070310456925e-06 26.2057252468907 5.13363122167055 5.10471518411153 4.5820787629883e-07 4.54845096945013 19.3223426805714 0.235398525150038 0.813987693319723 SPSB4 other 0.0186020916613863 1 0.00450693267127529 5.10471518411153 0.235398525150038 4.4585728492753e-11 24.6047979026921 8.65301816870742 2.84349315151935 0.00463642110913824 -119.324815965939 23.1757741706405 -5.14868737878459 3.71754559155256e-07 TRAF6 other 3.912843532524e-07 0.00480604294075915 1 2.84349315151935 -5.14868737878459 3.44414841280727e-09 40.253484528353 17.5537872655532 2.29315098328352 0.022264557213708 -167.914925092174 36.6204075656993 -4.5852828041557 5.77132384495929e-06 ZNF654 other 2.74016447722946e-05 0.0706698604815265 1 2.29315098328352 -4.5852828041557 9.8986797016345e-17 24.2169285955142 8.16692986606624 2.96524263005319 0.00315812623458496 -90.6398635164613 14.8235794152602 -6.11457334138552 1.85797493777232e-09 TVP23C other 1.07885710068114e-12 2.58760169583552e-05 1 2.96524263005319 -6.11457334138552 8.90088015470414e-33 124.615307807624 9.88354712228757 12.6083587466907 3.7157328560347e-32 -62.9953490788089 36.9427800045096 -1.70521409247271 0.0887253899108064 MRPS22 essential 1.24950555611737e-28 1 5.50262878650179e-28 12.6083587466907 -1.70521409247271 1.11111773424184e-11 305.756497698145 66.9608914472562 4.56619514898459 6.18874792225164e-06 -796.054559856045 194.382238368792 -4.09530503679934 4.87897372427632e-05 PACS1 other 1.00456154352805e-07 0.563472675416672 0.0566332322365248 4.56619514898459 -4.09530503679934 2.55219569547239e-13 2682.19236456566 418.527209593679 6.40864513246253 3.20634140963863e-10 -1098.57341260156 775.491485652685 -1.41661569846503 0.15717299583619 MARCKSL1 other 2.47256718977365e-09 1 3.63887686579888e-06 6.40864513246253 -1.41661569846503 2.99814538331111e-21 176.371619820462 17.7056061934173 9.96134319795471 1.70937915073165e-21 -130.821885613097 111.483213929243 -1.1734671167278 0.241150953588302 SH3BP5L other 3.63944868080136e-17 1 2.38219078445963e-17 9.96134319795471 -1.1734671167278 0.00910901654923371 16.6184926095294 8.44290634923618 1.96833790665378 0.0495383987087079 -13.7030252832753 13.7940636634949 -0.993400176884748 0.320958256098757 TMEM51-AS1 other 1 1 1 1.96833790665378 -0.993400176884748 1.46556485165288e-12 88.5061123504837 21.9884439848576 4.02511939505285 6.56444204671472e-05 -471.577726798816 85.0059831129605 -5.54758276452327 4.671674613851e-08 YPEL2 other 1.37631195218722e-08 0.00062521021357168 0.55180699844684 4.02511939505285 -5.54758276452327 0.162648617184539 8.68186500903515 15.3149910475072 0.566886717863818 0.571045539636458 -45.3932577967125 31.8168774727513 -1.42670373092357 0.154289433415279 CADM2 other 1 1 1 0.566886717863818 -1.42670373092357 0.114259881899721 31.2332228349077 21.6169656953901 1.44484768468538 0.149072216674652 -45.7052100080521 51.450414053607 -0.88833512516403 0.374750254906159 ABO other 1 1 1 1.44484768468538 -0.88833512516403 1.97240712308897e-50 1560.86221308311 92.3989826987044 16.8926341772916 1.43274050171343e-51 -0.433950043174488 406.207318309319 -0.00106829695974124 0.9991480229709 PSMD2 essential 2.98582990293209e-46 1 2.19925667013011e-47 16.8926341772916 -0.00106829695974124 0.00684229263133632 2.09818524823674 0.77395851834071 2.71097894591953 0.0069244292079143 -3.05137612532915 3.34554670327143 -0.91207099944095 0.362142904013337 FAM182B other 1 1 1 2.71097894591953 -0.91207099944095 0.221264412682776 15.4916903730657 8.91090306987886 1.7385095822029 0.0827233726684359 10.1622471447815 34.5300623363519 0.294301442198184 0.768647080909212 PPM1E other 1 1 1 1.7385095822029 0.294301442198184 7.10947731456715e-17 62.4411513053546 7.00598568852731 8.91254337096426 8.10177957699408e-18 -32.4256205773293 30.9632792012164 -1.04722824629167 0.295473465529224 FAM131A other 7.78061197306229e-13 1 1.08685373025376e-13 8.91254337096426 -1.04722824629167 4.86623716996639e-05 5.78059910399797 28.6030827642477 0.202097065957639 0.839918979898768 395.422906381265 89.0681688614412 4.43955356257974 1.09906661440185e-05 CSRP2 other 0.275623673306896 0.132382573704702 1 0.202097065957639 4.43955356257974 8.47372802549052e-34 203.012862331448 15.3156169455953 13.2552846583064 5.95620391508913e-35 -24.4877311068099 67.025386162148 -0.365350093583484 0.714992096147971 PARL other 1.19835461736487e-29 1 8.89797302875165e-31 13.2552846583064 -0.365350093583484 0.000487034533601254 86.6493968281901 22.2498908297818 3.89437402147648 0.000111391359739519 95.3807415088995 63.7674967291313 1.49575797077394 0.135328076568875 DDIT3 og 1 1 0.915971151138067 3.89437402147648 1.49575797077394 1.83868612218026e-27 113.687215569703 14.5770558221156 7.79905194553917 3.2293323777905e-14 -197.121949752837 34.7687915143737 -5.66950823330586 2.33253482640699e-08 PCCA other 2.45391049866177e-23 0.000315102129699321 4.06895879601602e-10 7.79905194553917 -5.66950823330586 1.22454079409114e-16 311.599455361478 42.1465848043759 7.39323142806879 5.84187747973659e-13 -355.623861140936 120.783472936426 -2.94430895630992 0.00338297911386402 DCTN2 essential 1.33107584317707e-12 1 7.13819009249014e-09 7.39323142806879 -2.94430895630992 3.09817561022474e-16 47.8515800666686 8.7995711465552 5.4379445622644 8.17809476287942e-08 -114.662862422746 25.3316942572478 -4.52645848549742 7.38380639690978e-06 ZNF408 other 3.32806024050341e-12 0.0898830752695828 0.000840053894042974 5.4379445622644 -4.52645848549742 0.00274823277500017 162.753717927075 144.145098834993 1.12909643992394 0.259371821754794 -1203.1569753447 414.690283539254 -2.90133871735822 0.00387134335423644 CTDSP2 other 1 1 1 1.12909643992394 -2.90133871735822 8.40777942668272e-23 1254.93733245065 131.085671637069 9.57341345379941 3.69597011145541e-20 -334.169770761023 378.18001475419 -0.883626203722655 0.37729125097108 CKAP5 essential 1.05088835054107e-18 1 5.09230761956327e-16 9.57341345379941 -0.883626203722655 8.15158037800306e-12 273.191378606296 92.625235414472 2.94942709061781 0.00332160102265809 -1401.71564164256 266.644147191598 -5.25687758912387 2.11390786116235e-07 ARHGAP1 other 7.42690488239859e-08 0.00275611306938347 1 2.94942709061781 -5.25687758912387 3.32489496884799e-23 178.826356363071 50.0825365297737 3.57063297416574 0.000388768913479691 -631.955009241727 89.5107956320981 -7.06009822367293 5.28661830104743e-12 MED16 other 4.17872799684816e-19 7.70524617377663e-08 1 3.57063297416574 -7.06009822367293 4.63366394824226e-29 384.017465444511 41.6195311574638 9.226857073224 6.26525103387824e-19 -504.157170730931 119.811888653642 -4.20790604668935 3.01825428006511e-05 ATG13 other 6.28788197776475e-25 0.353015020596415 8.51322310483375e-15 9.226857073224 -4.20790604668935 0.0350949951877965 5.13521519570015 3.23424456237744 1.58776341635876 0.112920867284878 -5.18206679934467 5.23532668771873 -0.989826826184696 0.322698820705977 C1orf127 other 1 1 1 1.58776341635876 -0.989826826184696 0.326446999450895 -74.8129718904096 77.0004216438645 -0.971591717204198 0.331691126606228 -312.424663690986 222.968067061514 -1.40120810934237 0.161729491479216 CHST1 other 1 1 1 -0.971591717204198 -1.40120810934237 0.000109398306459227 263.20773219099 65.0696994153235 4.04501226463336 6.00392774439884e-05 84.6122058408415 122.016737512401 0.693447534869894 0.488330246396144 GOLGA8A other 0.59129784641212 1 0.506311226685154 4.04501226463336 0.693447534869894 2.1455429520381e-05 404.246127357714 180.522617195125 2.23931014096017 0.0255458789264603 -1433.31425724151 469.711997444589 -3.05147465902357 0.00239021956615447 TP53I11 other 0.126351024445524 1 1 2.23931014096017 -3.05147465902357 7.5369530613761e-18 75.7333102759831 12.6060833907092 6.00767962012685 3.45059987567352e-09 -60.9861888391378 20.4249294799139 -2.98587022780726 0.00295524786100775 CENPS other 8.47907219404812e-14 1 3.7583933845836e-05 6.00767962012685 -2.98587022780726 6.82486560877746e-23 82.0319213137679 14.0486406308828 5.83913586154658 9.02213706112287e-09 -196.123865937043 31.0346688410795 -6.3195088995904 5.45963224731083e-10 DOLK essential 8.53858936314148e-19 7.69425972613515e-06 9.67173092952371e-05 5.83913586154658 -6.3195088995904 7.35457131379148e-10 -92.2615420348099 41.7315897071124 -2.21083219408451 0.0274619318056672 -609.592895373622 92.1887106945417 -6.61244626138062 9.03140528986244e-11 PHYHD1 other 6.06531496248383e-06 1.29212315482062e-06 1 -2.21083219408451 -6.61244626138062 1.54837410699356e-24 108.117326021973 9.83405024575315 10.9941807617532 1.81320043490246e-25 176.662943979425 113.889325216686 1.55118088234614 0.121455243007309 CCNE2 other 1.98795751596904e-20 1 2.60375582451994e-21 10.9941807617532 1.55118088234614 8.56068541866991e-25 141.42753754856 19.205311128152 7.36398054709198 6.67888533149967e-13 -273.639114097473 52.4820453012946 -5.21395674514086 2.63376526781452e-07 PHYKPL other 1.10304431619562e-20 0.00342336809510531 8.14623643883014e-09 7.36398054709198 -5.21395674514086 0.000676786958647306 27.5479393742822 9.18451903339269 2.99938834838542 0.00283236011696266 -37.4376534698813 26.1591951995463 -1.4311469899705 0.152977456355934 CST6 other 1 1 1 2.99938834838542 -1.4311469899705 8.90538533149503e-12 20.6473116994529 4.65558699150306 4.43495347356551 1.12400710829119e-05 -38.7399499092351 11.2005148393133 -3.45876510723056 0.000587096071479116 ZNF519 other 8.09232365072954e-08 1 0.100868397898052 4.43495347356551 -3.45876510723056 1.21932625447703e-136 307.36738986595 8.62156019863167 35.6510170763214 3.6557248709102e-133 -7.97902795033897 54.7067479014073 -0.145850891460754 0.884104409326196 LSM1 other 1.90909911663468e-132 1 5.7237684303841e-129 35.6510170763214 -0.145850891460754 7.70740066996279e-17 617.893724089404 81.2930446060035 7.60081907479416 1.34527171386548e-13 -503.738969100372 226.484464470383 -2.22416566309891 0.0265578244554501 BANF1 essential 8.42727189253732e-13 1 1.67002030559261e-09 7.60081907479416 -2.22416566309891 0.0217463475899265 3.19055571705833 3.15617071319228 1.01089453232752 0.312520488279593 -21.001066317023 9.39402664820036 -2.23557661730141 0.0257881841148513 APOF other 1 1 1 1.01089453232752 -2.23557661730141 7.24406967653217e-31 203.337325158078 43.5824386946572 4.66557933076391 3.88034570881063e-06 -805.322916103719 91.8468927029058 -8.76810191835962 2.33796841458676e-17 TMEM9B other 9.99029649090551e-27 3.56446664487897e-13 0.0359746850663834 4.66557933076391 -8.76810191835962 0.135821606513548 119.225349800536 164.129036092985 0.726412295098051 0.467899641164225 -485.643805647059 344.732495516225 -1.40875551902881 0.15948087752409 NRIP3 other 1 1 1 0.726412295098051 -1.40875551902881 3.59195326157886e-18 139.045253297513 19.5542124152262 7.11075702487732 3.76975368733057e-12 -120.618674892768 47.5117709346108 -2.53871140814288 0.0114121677031752 PTPN2 other 4.07076063134732e-14 1 4.52332744942795e-08 7.11075702487732 -2.53871140814288 7.53556379291379e-06 659.497206855281 1122.85874576986 0.587337640945312 0.557221554471742 -9940.56595938876 2358.42424202239 -4.2149184961161 2.92720618055787e-05 SCUBE2 other 0.0462985039436623 0.342805115805132 1 0.587337640945312 -4.2149184961161 6.14344582048525e-23 131.718177829525 15.323602115638 8.59577120545983 9.29174892909067e-17 -146.140659301921 42.7760459260289 -3.41641346548573 0.000683126184726242 EIF1AD essential 7.69220851182958e-19 1 1.22586043621493e-12 8.59577120545983 -3.41641346548573 2.70502773915821e-39 504.825266930751 51.9209946337678 9.72295061933248 1.06579893915693e-20 -576.927230452027 107.693943778194 -5.35710003935101 1.25385700299558e-07 SMAD2 ts 3.94879949362316e-35 0.00165195660144667 1.47485257200535e-16 9.72295061933248 -5.35710003935101 8.33804695803632e-17 177.059876517572 58.4005757855824 3.03181730891912 0.00254623576615647 -806.033673103808 125.71333074985 -6.41168019569612 3.11762156039919e-10 EIF3F essential 9.10514727817566e-13 4.41517565383733e-06 1 3.03181730891912 -6.41168019569612 0.000361921811764013 14.632697120137 9.88153666253566 1.4808119040447 0.139286556654206 -128.713773880961 38.8946951770063 -3.30928866507877 0.00100280863306034 ZNF25 other 1 1 1 1.4808119040447 -3.30928866507877 7.01957687676902e-07 43.742885858281 11.5380137386352 3.79119724149809 0.0001667595687592 158.754829491824 32.3338945294671 4.90985796180985 1.20807029955384e-06 ARL10 other 0.0047529555032603 0.0152808812190565 1 3.79119724149809 4.90985796180985 2.14102855667642e-05 220.436691240908 56.715626056469 3.88670118921776 0.000114204434289773 -176.449107061701 158.938714463646 -1.11017071993533 0.267417752196508 CLTB other 0.126106581988241 1 0.93796101882191 3.88670118921776 -1.11017071993533 0.553655757523574 -52.4402968915037 641.062298538307 -0.0818021852339053 0.934834050839851 -1532.82282244552 1490.24125588281 -1.02857360604843 0.30413635384407 PCSK1 other 1 1 1 -0.0818021852339053 -1.02857360604843 0.00152760740953916 1572.03124278918 504.911153557865 3.11348091978527 0.00194620487426024 537.058672145957 1029.2028881592 0.521820020449536 0.60200803960239 LPL other 1 1 1 3.11348091978527 0.521820020449536 7.11243747925447e-13 7.65645719359911 1.5694699184951 4.87837141914804 1.40681793201284e-06 -12.8974059964855 3.64462236800887 -3.53874961359347 0.000436419562749095 RFESD other 6.75325938655212e-09 1 0.0134083817100144 4.87837141914804 -3.53874961359347 2.64153673186981e-06 165.763616610501 35.6213578170921 4.65348955707027 4.09903976694663e-06 -135.44667360962 113.306314418174 -1.19540269494368 0.232447719048441 CCDC14 other 0.0169692319655316 1 0.0379284149635572 4.65348955707027 -1.19540269494368 0.547006740660722 6.02509455307849 6.77558270018368 0.889236368248469 0.374303676868521 -11.8088832401002 28.6502946615601 -0.41217318633529 0.680389140794271 TBC1D10C other 1 1 1 0.889236368248469 -0.41217318633529 3.89671509734353e-15 342.78980544013 47.6259071424924 7.19754910734894 2.10379803712703e-12 -269.353169368692 132.694260651261 -2.02987806742139 0.0428669825535023 SART1 essential 4.04050388443551e-11 1 2.5405465096346e-08 7.19754910734894 -2.02987806742139 6.3332934130256e-33 156.813127068307 17.7346324408323 8.84219775016367 1.35967004754277e-17 -196.601370995542 35.9646086755954 -5.46652329151992 7.04940313182799e-08 PPP2R2D other 8.90144389200747e-29 0.000937711604595759 1.81719901854092e-13 8.84219775016367 -5.46652329151992 0.00186069228208891 -8.93613777759575 12.0718795368799 -0.74024411445588 0.459471236471309 -97.8734368064389 27.9660111001366 -3.49972816845378 0.000503909110090678 MCTP1 other 1 1 1 -0.74024411445588 -3.49972816845378 1.79345995966302e-15 472.942989177341 59.6497847828221 7.92866212173727 1.46157240749024e-14 -254.806382236579 241.836327784296 -1.05363153902937 0.292561550686149 POLD4 other 1.87972538372281e-11 1 1.85356612717913e-10 7.92866212173727 -1.05363153902937 0.0436458167426639 7.41313821535032 4.79612502640548 1.54565157800029 0.122771319714735 -26.5633681052738 17.7978123345769 -1.49250748383651 0.1361469192513 LRRC25 other 1 1 1 1.54565157800029 -1.49250748383651 0.194646545666298 9.64224380279388 5.8604848884394 1.64529795509148 0.100488149377332 -5.44275359367219 15.2356556229446 -0.357237898280893 0.721052768541388 DPP10 other 1 1 1 1.64529795509148 -0.357237898280893 1.09051579418966e-09 36.1633447233938 5.55621291471177 6.50863191862938 1.84650184840936e-10 19.0361330114351 23.3626899598339 0.814809127038144 0.415569497436508 CLCF1 other 8.90733300694114e-06 1 2.10944371162285e-06 6.50863191862938 0.814809127038144 3.70182311859009e-41 8.19776554216551 0.605128896579159 13.5471394417092 4.09071148895315e-36 -5.49452437636568 2.59487026922346 -2.11745629118097 0.0346862183448351 LIPT2 other 5.44760290131718e-37 1 6.13034023734519e-32 13.5471394417092 -2.11745629118097 0.261640210764032 0.0404253431699019 3.16786462411253 0.0127610703002269 0.989823226460815 -21.2770190543362 13.5865173419122 -1.56603922247977 0.117937404138362 KCNE3 other 1 1 1 0.0127610703002269 -1.56603922247977 5.68706110119335e-17 57.2631022255137 6.89004087571961 8.31099600980714 8.97216419636479e-16 -37.1626050256759 28.5931701294062 -1.29970216165212 0.194300757592263 CABP4 other 6.24098085244959e-13 1 1.16279247984888e-11 8.31099600980714 -1.29970216165212 2.15230883879135e-06 36.5482838643293 14.8888449317495 2.45474273067298 0.0144361516429726 -202.776781635076 50.4222945225655 -4.02156989393506 6.6684008842232e-05 ALG10B other 0.0139491135842067 0.76153138097829 1 2.45474273067298 -4.02156989393506 5.22590174045258e-10 570.555897675544 91.3365103952096 6.24674508810081 8.59861406600747e-10 -94.9402580382049 253.654567588507 -0.374289566085096 0.708338310240642 DRAP1 other 4.3474276578825e-06 1 9.59691315907093e-06 6.24674508810081 -0.374289566085096 0.36193461712366 8.5132728863392 8.64553121440397 0.984702116644443 0.325230118393333 -19.9030363628087 30.8737400434024 -0.644659064137643 0.519433529646668 UCP3 other 1 1 1 0.984702116644443 -0.644659064137643 1.93271207592538e-13 830.667854563063 131.758873301181 6.30445474942916 6.19716005783887e-10 -1100.59569435517 470.519289310401 -2.3391085538028 0.0197089949091126 UCP2 other 1.88110866349817e-09 1 6.953833300901e-06 6.30445474942916 -2.3391085538028 1.07701971565083e-13 149.664832561266 25.1602378188023 5.94846653036884 4.91414926413926e-09 -227.891186812674 69.8735830473224 -3.26147847117462 0.00117948831734508 C11orf68 other 1.05827957259851e-09 1 5.32251506798923e-05 5.94846653036884 -3.26147847117462 3.35215162314507e-55 179.592088274946 11.3616247118821 15.8069019906217 3.4695188847648e-46 -114.866147304933 40.4687879630889 -2.83838862210801 0.00471281954573397 PAAF1 other 5.11337208594549e-51 1 5.29483277003956e-42 15.8069019906217 -2.83838862210801 2.23546420392436e-66 172.758253080446 9.22215104785454 18.732967198649 4.26624672850997e-60 -38.7955864471691 32.9205812886157 -1.17845994598476 0.23915750299232 MRPL48 other 3.45334510222235e-62 1 6.59305769423931e-56 18.732967198649 -1.17845994598476 1.27078647224997e-61 1843.86956166776 101.721523898694 18.1266411571271 3.46773298058296e-57 -99.8669771589014 364.163461469007 -0.274236675903854 0.784012494942646 RAB6A other 1.95599453808716e-57 1 5.34967166914534e-53 18.1266411571271 -0.274236675903854 3.74045736181085e-11 53.8972873848269 10.5976990257193 5.08575373333634 5.20109247237683e-07 -87.6104747586446 32.3102268483432 -2.71154006964631 0.0069295371959764 P2RY2 other 3.29796125590863e-07 1 0.00509603040443481 5.08575373333634 -2.71154006964631 0.079844161481537 27.3982804698484 12.6390119513197 2.16775493016189 0.0306209161902685 2.34385289005511 34.7902910363616 0.0673708905626973 0.946311801725172 FOSL1 other 1 1 1 2.16775493016189 0.0673708905626973 1.46054317920362e-16 76.6129797402535 9.93129306945412 7.71430056534064 5.8746762773996e-14 -104.632068427165 51.8181900925242 -2.01921503318312 0.0439566266238879 ERCC4 other 1.58264458898504e-12 1 7.35568216693204e-10 7.71430056534064 -2.01921503318312 0.265041736342675 7.39112604098123 5.31359729051925 1.39098347821142 0.164797008955169 23.663903988734 20.3381814951147 1.16352113360863 0.245126340216318 SUGCT other 1 1 1 1.39098347821142 1.16352113360863 0.248006112032246 31.5883235604274 24.7505721712919 1.27626639666402 0.202420340479401 -43.9285497570194 67.986753671157 -0.64613395087955 0.518472277896743 CCDC85B other 1 1 1 1.27626639666402 -0.64613395087955 1.10758679246964e-59 184.645679281792 9.80710352271155 18.8277485655356 9.31568885194345e-61 29.3244604919167 98.6291134466474 0.297320532114278 0.766339862710278 TMEM70 other 1.70081027851637e-55 1 1.44020549651046e-56 18.8277485655356 0.297320532114278 5.02161046356717e-06 7.13715423060739 2.37179825801818 3.0091742442593 0.00274140681110102 -13.6651176747763 4.94414471582906 -2.76389921011542 0.0059058138734863 LINC00476 other 0.0313323342335238 1 1 3.0091742442593 -2.76389921011542 1.05795472256116e-32 298.046059866796 23.995787084121 12.4207661462385 4.7083066589263e-31 -102.831217052371 101.683936814462 -1.01128280703768 0.312371196058838 RPS6KB2 other 1.48388729386429e-28 1 6.94898979790933e-27 12.4207661462385 -1.01128280703768 4.56415762252638e-12 104.331170963541 14.194103703926 7.35031764877717 7.34664571472841e-13 97.4024149142355 73.9076217007245 1.31789405034096 0.188096885582126 RMI2 other 4.20267633882229e-08 1 8.95335713253951e-09 7.35031764877717 1.31789405034096 6.52278643713982e-31 1.28120573548164 65.3006455135524 0.0196201082761998 0.984353905551328 -1268.86833856552 114.899550665345 -11.0432837310322 1.25047567681534e-25 TOM1L2 other 9.00125342287139e-27 1.94861624718134e-21 1 0.0196201082761998 -11.0432837310322 2.40539392117383e-09 22.1427522265396 4.74237429457263 4.66912792013922 3.81172553061214e-06 -19.895510271258 9.99931275926782 -1.98968776657356 0.0471237145963892 ZNF77 other 1.93153131870259e-05 1 0.0353613777474888 4.66912792013922 -1.98968776657356 0.000636431289333178 16.8806101960329 4.65499314426606 3.62634480285456 0.000314545452695569 28.671049968829 14.9847506616811 1.91334848447939 0.0562290080319064 GPR156 other 1 1 1 3.62634480285456 1.91334848447939 3.85583162184074e-13 53.3001549535046 20.5342595907251 2.59566967671818 0.00969613048015911 -152.948375093377 31.8602503236206 -4.80060180129796 2.04804422222787e-06 KDF1 other 3.70121277380493e-09 0.025633321485404 1 2.59566967671818 -4.80060180129796 3.12573225382442e-13 60.9900778327547 9.2387251883771 6.60156857024864 1.00892947767001e-10 -74.5505524294797 26.3055928814098 -2.83401909113269 0.00477602350420891 B3GNTL1 other 3.01695677139133e-09 1 1.16218586532809e-06 6.60156857024864 -2.83401909113269 0.000353214975239125 218.621963222613 79.2707737098286 2.7579138311792 0.00601312251087751 633.938002808327 174.855004681456 3.62550676752553 0.000315542954274365 MLXIP other 1 1 1 2.7579138311792 3.62550676752553 0.202503715576735 70.1466444916694 95.8861678983672 0.731561663471838 0.464751742855006 -259.639746758446 213.729834543502 -1.21480347988385 0.224969039907061 NR2F1 other 1 1 1 0.731561663471838 -1.21480347988385 2.95518172074797e-06 275.43767197473 93.3713171921473 2.94991738638442 0.00331931739330074 -422.055779509629 177.906509477583 -2.3723459065606 0.0180322501467724 AURKAIP1 essential 0.0188836111955795 1 1 2.94991738638442 -2.3723459065606 1.33324615406289e-16 10.9575392949827 2.27046597105471 4.82611914676375 1.81363141106978e-06 -32.8537838386602 5.63773061498972 -5.82748380195887 9.67219240809317e-09 TTLL11 other 1.44697205100446e-12 0.000132305919950307 0.017178716725653 4.82611914676375 -5.82748380195887 6.83223796886995e-29 339.406154187854 30.8674959763768 10.9955843016099 1.67017485741621e-25 -91.886111793761 76.3176778644681 -1.20399512098548 0.229121898107466 TOMM5 other 9.25631600022501e-25 1 2.3988721477069e-21 10.9955843016099 -1.20399512098548 4.6455938376063e-22 131.310768905378 13.3266098999079 9.85327625642334 4.09044758574106e-21 -142.448474274493 65.2716037718488 -2.18239580526334 0.0295270570587603 SLC35E3 other 5.73126911745489e-18 1 5.68204074135291e-17 9.85327625642334 -2.18239580526334 0.530091811715096 0.0239829494677375 8.83551602033019 0.00271438016891754 0.99783523205596 -18.4137990350364 17.9252634324738 -1.02725402638589 0.304755729592792 PRIMA1 other 1 1 1 0.00271438016891754 -1.02725402638589 2.951924834576e-08 4.19735622021437 2.32773718408384 1.8031916355997 0.0719143978933853 -24.3497234872173 5.07449244876228 -4.7984549653151 2.07112949888537e-06 ZNF169 other 0.000222102824553498 0.0259181145490516 1 1.8031916355997 -4.7984549653151 3.90557096683938e-35 494.666474889519 38.2412255765389 12.9354242033759 1.62142167278022e-33 -162.11125423744 124.761683188939 -1.2993673225131 0.194374422562998 RUVBL1 essential 5.57793645484001e-31 1 2.41283759126424e-29 12.9354242033759 -1.2993673225131 0.00196432014361886 894.515223035353 278.367349789916 3.21343441933993 0.00138926189724443 188.816288568336 431.735499089447 0.437342514031298 0.662036532398517 SFN other 1 1 1 3.21343441933993 0.437342514031298 1.61315795113742e-35 60.6127577613882 6.68084361361794 9.0726203555847 2.1670728359292e-18 -64.4115813038363 16.9584898065477 -3.79819087894058 0.000162339081726834 MSRA other 2.31004218602879e-31 1 2.9259817430716e-14 9.0726203555847 -3.79819087894058 8.28083297033894e-38 315.464770124961 38.3625503202754 8.22324812848094 1.48403993625145e-15 -488.374225865976 69.8240047551445 -6.99435999952428 7.91201175465403e-12 CTDNEP1 other 1.20055516403974e-33 1.15056474936179e-07 1.91574715370699e-11 8.22324812848094 -6.99435999952428 4.15740653672688e-06 101.947063048495 30.8500079802334 3.30460410622311 0.00101455790574169 330.142150464688 68.6425369677433 4.80958549972926 1.96726994775502e-06 ETV4 other 0.0261542445225488 0.0246479251754226 1 3.30460410622311 4.80958549972926 5.23069384537352e-08 55.7198091435946 16.9209333318489 3.29295128411846 0.00105606348345808 -131.73518577608 37.9340367388824 -3.47274366508564 0.000556312692342589 SWI5 other 0.00038707134455764 1 1 3.29295128411846 -3.47274366508564 1.15996808381877e-05 -18.8586162468079 6.15567071122312 -3.06361680660153 0.00229652024796422 -65.8701037610481 14.1673639879477 -4.64942552595417 4.19474937723148e-06 GAPT other 0.070131670347683 0.0517464283175276 1 -3.06361680660153 -4.64942552595417 1.13046791550464e-11 272.838364619881 60.9300461710191 4.47789525473319 9.23018306143802e-06 -833.391986375958 171.464512261265 -4.86043424021231 1.54375839014105e-06 BAIAP2 other 1.02171690203309e-07 0.0194312868567053 0.0834316246923383 4.47789525473319 -4.86043424021231 0.0990334797020951 -9.07079257621913 20.4681041118509 -0.443167209168494 0.657824611014868 -107.538217104893 50.0701819041844 -2.1477496788544 0.0321838130273584 HOXD8 other 1 1 1 -0.443167209168494 -2.1477496788544 2.49553506841294e-16 67.8092931072445 21.2531734032036 3.19054909216631 0.0015026734755763 -316.077264290435 49.2785860929308 -6.41408955391635 3.10168551490637e-10 ZDHHC21 other 2.68893903621494e-12 4.39291719476189e-06 1 3.19054909216631 -6.41408955391635 6.92288825991051e-21 395.472041800261 40.5726178361158 9.74726460584044 9.27747424055845e-21 -963.877060462397 455.716790300762 -2.11507910390192 0.0348892409726137 PLEKHF2 other 8.35038781910405e-17 1 1.28483740757494e-16 9.74726460584044 -2.11507910390192 0.618308455099408 1072.66319867683 1109.21352438525 0.967048431248908 0.333947185819339 427.757994864754 3681.88197754278 0.116179170726769 0.907553183832293 A2M other 1 1 1 0.967048431248908 0.116179170726769 8.36541757805558e-07 3.20815936323133 10.1096318001146 0.317336914604046 0.751111544406517 -107.160331893285 22.5266351954547 -4.75705008597588 2.52910636628244e-06 ARL4D other 0.0056290894882736 0.0315430146002746 1 0.317336914604046 -4.75705008597588 1.25554355136698e-06 -62.4362054776173 33.7029908708203 -1.85254198112352 0.0644894729225098 -341.20649954431 65.5015393728648 -5.20913711053425 2.69635294254613e-07 DOK7 other 0.00830667613584392 0.00350337137825018 1 -1.85254198112352 -5.20913711053425 0.26470107492953 -79.8420560865475 54.6957266250638 -1.45974943589031 0.144951405566695 -134.217126831702 137.810592234844 -0.973924606629521 0.330538263092319 LRRN1 other 1 1 1 -1.45974943589031 -0.973924606629521 1.24600260433773e-52 349.577191423848 20.5241197480947 17.0325059351839 1.94952502994679e-52 40.190547404324 65.8367172451685 0.610457949394089 0.541813901282881 UBE2O other 1.89330095729118e-48 1 2.99466539850127e-48 17.0325059351839 0.610457949394089 8.94292343206361e-37 206.985182116437 17.6524269149566 11.7255934899842 2.39337053209331e-28 -482.570514402334 105.701429233808 -4.56541144145654 6.22379185360963e-06 ORAI3 other 1.28885412502901e-32 0.0760547364511097 3.49264561748377e-24 11.7255934899842 -4.56541144145654 0.583214511793159 5.65861234411183 5.6680517957293 0.998334621496477 0.318564264780452 -17.7070480377551 64.2811084272094 -0.275462705466665 0.783066147514597 KLHL38 other 1 1 1 0.998334621496477 -0.275462705466665 0.149632582645502 6.41387664111459 3.80417187953522 1.68601126453261 0.0923712766674788 -2.0895426185168 8.90389277979559 -0.234677423705991 0.814548067932391 DENND2C other 1 1 1 1.68601126453261 -0.234677423705991 0.00422316710396392 13.0040616386067 19.8915015795783 0.653749621997235 0.513553488094203 -101.550514210871 38.910668434056 -2.60983730934806 0.0093117633981803 PLEKHD1 other 1 1 1 0.653749621997235 -2.60983730934806 1.58298436585769e-07 432.587250028747 82.414271185017 5.248936183123 2.21565024047643e-07 29.9661978799595 196.110332691382 0.152802748680852 0.878611875228271 TUBB6 other 0.00112952167670768 1 0.00222008154095738 5.248936183123 0.152802748680852 5.65843126679861e-13 79.7024228250851 22.0266014708534 3.61846210957922 0.000323993902346097 -235.906743363738 48.991661873895 -4.81524272377133 1.90827199286762e-06 LYSMD3 other 5.39191915413239e-09 0.0239201894305956 1 3.61846210957922 -4.81524272377133 0.00821225253248064 9.44010910436322 7.93544888988979 1.18961248889026 0.234752255007715 -28.1665213699193 14.3853528751259 -1.95800003061605 0.0507748090086597 AMIGO3 other 1 1 1 1.18961248889026 -1.95800003061605 5.76227363762817e-11 53.6224298171591 27.1949227411197 1.9717809212997 0.0491652423015631 -259.7209000415 50.8630818271675 -5.10627533195945 4.62111607566153e-07 B3GALT6 other 5.03392224983197e-07 0.00595477017509744 1 1.9717809212997 -5.10627533195945 5.96446843920313e-07 49.9479454146023 9.25690693998488 5.39574889738319 1.0213754313546e-07 12.3323515016653 39.23299396716 0.314336232202622 0.75338663991728 ZNF613 other 0.00405941721972165 1 0.00104221149015423 5.39574889738319 0.314336232202622 1.08683194778834e-08 733.142750944264 132.572526037092 5.53012583270185 5.01514169598751e-08 -1044.10597879057 793.388633710917 -1.31600823912358 0.188735920805659 NUPR1 other 8.38382164523926e-05 1 0.000520872616545263 5.53012583270185 -1.31600823912358 0.732804249937905 -1.99514188628226 6.04127608898649 -0.330251731073753 0.741335976549448 7.97041381292311 14.3356359154467 0.555986065768798 0.578447308890317 JAKMIP2 other 1 1 1 -0.330251731073753 0.555986065768798 4.14806468683431e-15 20.6928767328453 8.12118203147766 2.5480129188879 0.0111076663204928 -114.36530292972 18.0631680574502 -6.3314088960463 5.08798775264513e-10 MBLAC2 other 4.29739501556035e-11 7.1730451336791e-06 1 2.5480129188879 -6.3314088960463 7.59585428739896e-10 28.6051513887008 52.5328592780014 0.544519216769142 0.586324107390441 -742.059116513153 122.216476153289 -6.07167822104795 2.48681077566968e-09 TPRN other 6.25670517653052e-06 3.45293676201735e-05 1 0.544519216769142 -6.07167822104795 0.243514496504375 11.1297388515198 7.73911806878838 1.43811462140702 0.15097443833085 18.8948904677985 12.7131641433718 1.4862460874974 0.137791221340839 ZNF683 other 1 1 1 1.43811462140702 1.4862460874974 2.83536791667497e-29 259.280324980357 39.1025335796056 6.63078069998992 8.07663002165073e-11 -669.067561531053 92.582050466506 -7.22675246616088 1.68594369222834e-12 SLC35A4 other 3.85439914592795e-25 2.47142485843752e-08 9.33012300101092e-07 6.63078069998992 -7.22675246616088 0.0141818978266043 28.1739361225384 9.62335556989927 2.9276623853184 0.00355761407301111 24.786050768413 15.8084290590639 1.56790093916395 0.117483586814237 CRYBG2 other 1 1 1 2.9276623853184 1.56790093916395 4.32381275157883e-35 83.9050316170029 35.9007836694275 2.3371364923283 0.0198121493074737 -689.524395443886 65.2760007667895 -10.5632144638784 9.40700875334061e-24 IP6K1 other 6.1731074654291e-31 1.4617550901816e-19 1 2.3371364923283 -10.5632144638784 4.71744531015958e-07 180.043362960689 45.642632902216 3.94463140078731 9.12049119368708e-05 -247.672424770237 106.186524631127 -2.33242801410637 0.020069445297608 SSNA1 other 0.00323663922730049 1 0.756271129780533 3.94463140078731 -2.33242801410637 1.59088712675658e-15 134.025570956125 16.4243147659558 8.1601925478153 2.37310885025698e-15 -62.3082733766049 73.1246421111428 -0.852083122429536 0.39454639101587 CSTF3 essential 1.66947695081836e-11 1 3.05276722497058e-11 8.1601925478153 -0.852083122429536 2.19765001238696e-17 624.209982601131 78.8218452784772 7.91925107050972 1.43851439988276e-14 -56.2740790966229 172.383854089656 -0.326446344953832 0.744217020195266 YES1 other 2.43895198374705e-13 1 1.82504321913125e-10 7.91925107050972 -0.326446344953832 3.62282316011365e-13 70.8355843551786 13.5337347700352 5.23400122426031 2.38034152689714e-07 -180.474082762018 38.2172163538387 -4.7223241245798 2.97723606745513e-06 CHMP6 essential 3.48443131539731e-09 0.0369862036659951 0.00238034152689714 5.23400122426031 -4.7223241245798 5.00377340494801e-10 26.5374839506283 5.99594374950397 4.42590608906624 1.16406951258872e-05 -21.3151686220718 11.0531487899298 -1.92842501509536 0.0543300886948661 DLEU1 other 4.16664211430021e-06 1 0.104335550413327 4.42590608906624 -1.92842501509536 7.67933196079611e-05 5.94467906788825 2.2553160188572 2.63585192415762 0.00863262478909016 -18.3979518016844 7.10190681999331 -2.59056507892929 0.00983929807083061 UFSP1 other 0.423899124235945 1 1 2.63585192415762 -2.59056507892929 2.54154320902297e-07 96.0364714626519 19.8065889754629 4.8487133035186 1.62648438072883e-06 -123.192028723294 62.7231624618802 -1.9640595896 0.0500347619060442 TMEM39A other 0.00178441748705503 1 0.0154516016169239 4.8487133035186 -1.9640595896 2.00855872434582e-21 54.4499360967771 5.52193597978319 9.86066051763877 3.37428568470677e-21 -17.5281898455916 24.5848668901098 -0.712966636099338 0.476174948120256 TCP11L1 other 2.44602281450834e-17 1 4.68991967317394e-17 9.86066051763877 -0.712966636099338 0.00141148249016785 261.881141362421 81.677696587979 3.20627481310442 0.00142437697557673 471.411698107325 161.852410709178 2.91260226549467 0.00373287584492871 GPX2 other 1 1 1 3.20627481310442 2.91260226549467 1.52313061313334e-12 96.0575274528995 34.4440706394351 2.78879719120431 0.00548134159933544 -627.400978108486 98.1039917142601 -6.39526452640039 3.53233701475071e-10 CCDC57 other 1.42945808042564e-08 4.99719717476783e-06 1 2.78879719120431 -6.39526452640039 1.54889778740473e-07 33.3948811144611 28.3453258852004 1.17814419385092 0.239255181944411 516.129796309603 90.847534948036 5.68127463893021 2.18221580047897e-08 SPHK1 other 0.00110668746910068 0.000295035576224757 1 1.17814419385092 5.68127463893021 1.66629349096272e-11 424.785192521462 59.2912587156403 7.1643814235539 2.61327986118291e-12 243.347235107133 119.802012684143 2.03124496538064 0.0427258258458168 BNIP3 other 1.4929989679026e-07 1 3.14795692078093e-08 7.1643814235539 2.03124496538064 4.43279477830688e-11 24.459681578497 4.58677664496311 5.33265154852416 1.41947749900006e-07 -33.8074560557135 13.533002480453 -2.4981489587802 0.012777359816357 MYPOP other 3.89066397691995e-07 1 0.00143594343798846 5.33265154852416 -2.4981489587802 0.529431456972619 17.0522655612222 30.5014904378225 0.559063354493556 0.576353740095064 81.1887074330717 72.280813470352 1.12324009007416 0.261842163501855 CIDEA other 1 1 1 0.559063354493556 1.12324009007416 1.81446288438184e-26 85.1807978947406 7.39384010688979 11.5205085129399 1.71349918554221e-27 99.1245679947891 18.6832536965818 5.30553026815261 1.66917244469718e-07 ATAD5 other 2.39128063532682e-22 0.00218678281979778 2.48920026683717e-23 11.5205085129399 5.30553026815261 5.0161600738576e-45 262.327449861472 18.1662824443111 14.4403485229099 2.17416184434308e-38 -217.906678123594 80.9865380816373 -2.6906530799469 0.00742787368076873 SMIM19 other 7.49013022228417e-41 1 3.27493998613399e-34 14.4403485229099 -2.6906530799469 0.0105560238598441 3.77931042542652 3.59983388254679 1.04985689582786 0.294248370327798 -26.6502086621944 11.3211338033116 -2.35402293844444 0.0189248101794797 ZNF404 other 1 1 1 1.04985689582786 -2.35402293844444 4.7005197538026e-16 86.9739502311166 12.9332512565605 6.72483264306789 4.53135505975147e-11 -54.2802221094732 26.4952568746245 -2.04867695249482 0.0409819957908971 RTTN essential 5.01874494113504e-12 1 5.26860652797303e-07 6.72483264306789 -2.04867695249482 1.70330001503885e-08 14.9448332729978 2.70806292709572 5.51864327946968 5.29312322991284e-08 36.5200343366479 10.6164892912817 3.4399351174063 0.000626495236747871 ACBD7 other 0.000129995857147765 1 0.000549055672638859 5.51864327946968 3.4399351174063 6.00695354404396e-16 91.2993843781331 30.8127084756188 2.96304313690488 0.00318925618888067 -482.770915107891 71.565005649499 -6.74590759445109 4.16054034578558e-11 ANAPC2 essential 6.3938013522804e-12 5.98452123337798e-07 1 2.96304313690488 -6.74590759445109 6.50477196109821e-19 81.4080566239377 11.4041382353304 7.13846631319608 3.0660795908628e-12 -58.2477618228741 21.1307936496909 -2.75653450544798 0.00603965396640625 ZBTB8OS other 7.49870111675402e-15 1 3.68726731597161e-08 7.13846631319608 -2.75653450544798 8.79486261256815e-06 19.2296355974542 5.7473556461431 3.34582315440297 0.000876898645016797 50.5340848214868 11.0862526516864 4.55826566552223 6.37271423639854e-06 SLC35G1 other 0.0537454054254039 0.0778363316833718 1 3.34582315440297 4.55826566552223 8.62257491936315e-11 190.46759227298 30.9862453024473 6.14684323363106 1.55747502099277e-09 -289.821040755665 141.936607398979 -2.04190480572068 0.0416564276272627 ZNF135 other 7.45852730524913e-07 1 1.71867368566552e-05 6.14684323363106 -2.04190480572068 1.62988685103447e-07 546.704745209367 131.303786866934 4.1636631985596 3.65513883847115e-05 -536.483227780702 302.055475216347 -1.77610827082822 0.076288714873978 COX8A other 0.00116194633610247 1 0.314451594273673 4.1636631985596 -1.77610827082822 6.21127940172494e-17 63.1981520756517 8.51530739483545 7.42171117791726 4.5662143476984e-13 -64.7653572499717 22.2050506431415 -2.91669486779468 0.0036858434673339 ZSCAN2 other 6.80694109635036e-13 1 5.59315595449577e-09 7.42171117791726 -2.91669486779468 8.73515750833376e-16 135.365568620862 20.9961103437644 6.44717361475784 2.52334421877257e-10 -164.009731521627 46.2215296251331 -3.54834062939462 0.000421305822560227 B3GNT4 other 9.25664641158128e-12 1 2.87055638327568e-06 6.44717361475784 -3.54834062939462 6.98706448684268e-07 13.7169694077104 5.46533778759397 2.50981182514412 0.0123677762904598 -44.6228161061894 12.1258083282228 -3.67998692526995 0.000256382036636587 CDC26 essential 0.00473233877693854 1 1 2.50981182514412 -3.67998692526995 0.0015832089679737 90.402325270705 35.9084365407631 2.51757898643348 0.012111279039162 -47.7724040243489 78.9008473367518 -0.605473903473489 0.545124316192112 HSD11B2 other 1 1 1 2.51757898643348 -0.605473903473489 4.51340492180939e-19 87.0224844820773 9.42721232537773 9.23098806715276 6.83061772131165e-19 33.7403381934524 24.2504560696517 1.39132798560753 0.164723231186743 CRLF3 other 5.22968228290054e-15 1 9.28007723617401e-15 9.23098806715276 1.39132798560753 9.46790967582788e-21 473.441537167893 49.1795301736071 9.62680073389502 2.31778705175213e-20 -971.619822363441 362.639140414086 -2.67930213284198 0.00760095131724065 RNPEP other 1.13861081761506e-16 1 3.19877791012312e-16 9.62680073389502 -2.67930213284198 1.00907643387195e-58 84.34717736621 4.73651129598346 17.807869990247 3.42758345168636e-56 -31.0771621883549 25.6166185978006 -1.2131641055476 0.225595532360003 EID2 other 1.54782234191619e-54 1 5.28224885739385e-52 17.807869990247 -1.2131641055476 0.00266018636070417 19.8199156472535 6.15253651451689 3.22142186405371 0.00135540598699527 33.5648402410754 14.0401031095277 2.39064058000387 0.0171737892418266 DMRTA1 other 1 1 1 3.22142186405371 2.39064058000387 1.13131348354107e-06 3.40653975716249 1.00268929296827 3.39740314477486 0.000730242462810266 -16.9284810487502 5.30310904004911 -3.19218045884145 0.00149390689502311 EID2B other 0.00751079021722915 1 1 3.39740314477486 -3.19218045884145 2.52389923859686e-06 -10.4510728969171 7.99854999099336 -1.3066209386308 0.191899745225578 -131.176741933553 25.5313448703664 -5.13787043336704 3.89295513890332e-07 GJC3 other 0.0162412916003708 0.00502814085740753 1 -1.3066209386308 -5.13787043336704 0.283696018525679 8.4080237973634 5.83270375826953 1.44153108846693 0.150021957993544 -48.4477976655904 72.8247168694057 -0.665265856817135 0.506168226920244 RIMS2 other 1 1 1 1.44153108846693 -0.665265856817135 1.39216010050057e-15 279.936713370193 34.1054922798469 8.20796577493206 1.63393225434414e-15 -143.031746275617 122.191842640087 -1.17055069459026 0.242291001546583 KCMF1 essential 1.46497007375674e-11 1 2.10842618100568e-11 8.20796577493206 -1.17055069459026 7.38406349924487e-12 46.840260133679 10.3468969764415 4.52698622981634 7.39144405333961e-06 -179.705402343576 38.473969490036 -4.67083081692716 3.80563563566405e-06 DNAJC30 other 6.73936317824795e-08 0.0470034057360867 0.0672547494413371 4.52698622981634 -4.67083081692716 1.78514644670015e-21 76.9535946035065 14.6443593875562 5.25482833130255 2.13782446859322e-07 -307.865890552605 43.3055496938661 -7.10915558696193 3.72418711046525e-12 SPRYD4 other 2.17591500388281e-17 5.43619592514612e-08 0.00214381037710529 5.25482833130255 -7.10915558696193 2.8241862146232e-05 13.4867319896786 5.58039125044003 2.41680760083178 0.015993348782678 -69.1446753609036 20.7501633775552 -3.33224727452966 0.000921480298946599 VPS37D other 0.164254670242485 1 1 2.41680760083178 -3.33224727452966 1.41706523404581e-10 -61.1817671174869 19.9477716936595 -3.06709782210581 0.00227228551359275 -326.075824971343 47.8624865024023 -6.81276399952552 2.61720443842212e-11 CLEC14A other 1.21371637296024e-06 3.77714944553081e-07 1 -3.06709782210581 -6.81276399952552 0.411117324344406 -10.9921944236147 38.5317020153535 -0.285276638421907 0.775540391386147 -104.553821664736 79.7287537870086 -1.31136906948334 0.190284289367269 SYNE3 other 1 1 1 -0.285276638421907 -1.31136906948334 1.30245820005361e-25 167.924149266075 14.903966082074 11.2670780610571 1.56700735111598e-26 64.5685238784369 154.684534412624 0.41742068218791 0.676540728242756 CLK2 other 1.69710303466985e-21 1 2.26479572456793e-22 11.2670780610571 0.41742068218791 5.75149070660163e-10 91.3868098960383 16.6065443279884 5.50306000400195 5.76946809081773e-08 -16.2635025408553 30.5070960654777 -0.533105560291571 0.594179431235563 LPCAT4 other 4.77373778866497e-06 1 0.00059731303144236 5.50306000400195 -0.533105560291571 0.043197477730417 69.8392816127459 29.1477152997785 2.39604651323312 0.0169148137171679 -12.1938949915356 75.4219612419303 -0.16167565508435 0.871622200479 SLCO3A1 other 1 1 1 2.39604651323312 -0.16167565508435 6.42178149033877e-08 10.1148580948112 4.26325486768844 2.37256706641503 0.0180110717630606 -59.9159983860273 13.7821216123696 -4.34737118646899 1.64438235436091e-05 ZNF575 other 0.000471166107946156 0.196109039581082 1 2.37256706641503 -4.34737118646899 3.97312206458685e-37 28.0868191820312 7.21065913130301 3.89518054737885 0.000110363847757973 -162.622700652338 14.8212922342835 -10.972234949674 1.94674496060551e-25 WDR25 other 5.73877751008925e-33 3.03302864862339e-21 0.908184103200358 3.89518054737885 -10.972234949674 1.55139213644908e-17 72.3238429135662 9.0161740420493 8.02156686153849 6.67446655867669e-15 -125.184676069623 54.253662298222 -2.30739586539811 0.021415024775293 SGF29 other 1.72964709292708e-13 1 8.5199565621508e-11 8.02156686153849 -2.30739586539811 1.15960029358311e-05 262.326915341839 149.17449668207 1.75852388428652 0.0792376963914965 -1279.08195054253 374.959047150667 -3.41125773671108 0.000696176656778233 PLA2G16 other 0.0701210297529706 1 1 1.75852388428652 -3.41125773671108 1.65455634279003e-06 144.71542045974 27.7288460019946 5.21894854366928 2.56545245234687e-07 145.685776966644 57.8901235040683 2.51659122745533 0.012136674701054 DIRAS1 other 0.0108307258199035 1 0.00256057809268741 5.21894854366928 2.51659122745533 4.26813714852442e-08 30.3396829380286 15.1379828610871 2.00420909552079 0.0455410634139238 -228.198427344741 48.613383200522 -4.69414824315889 3.38966308901897e-06 PHLDB3 other 0.000317037227392394 0.0419945360098561 1 2.00420909552079 -4.69414824315889 0.000166749221089102 61.946281716096 51.4772206163848 1.20337269523015 0.229360395118593 -790.43121276318 213.747444687861 -3.69796801041276 0.000239598306837908 PRR15 other 0.879935639687189 1 1 1.20337269523015 -3.69796801041276 0.000609000409201791 -1.5975587244455 20.1708412951724 -0.0792013927960381 0.936901615490576 -143.844557765575 41.1672790189533 -3.49414780849007 0.000514395478208766 GNG7 other 1 1 1 -0.0792013927960381 -3.49414780849007 1.78560208058378e-10 108.957253764903 24.3617764224932 4.47246751941716 9.42127325333654e-06 -361.101254312472 81.7310256692529 -4.41816619032493 1.20211224224e-05 USF3 other 1.52365425536214e-06 0.144409743660291 0.0850835187508823 4.47246751941716 -4.41816619032493 1.90159108593268e-60 170.269415875565 19.9053785138954 8.55394012008885 1.26303326933809e-16 -536.611188541772 44.3763165673701 -12.0922877347676 6.37406052306048e-30 CNTD1 other 2.92407661283868e-56 9.97285509438042e-26 1.66152026581426e-12 8.55394012008885 -12.0922877347676 4.24775600999897e-07 37.9428618741735 12.573946552419 3.01757779198401 0.00267461681521396 -43.6684387227739 26.1914701048399 -1.66727711533476 0.0960696245556656 KBTBD11 other 0.00292882776889429 1 1 3.01757779198401 -1.66727711533476 2.13165540369806e-15 189.158273379089 24.5574432778447 7.7026859530505 6.35953399293767e-14 336.089988218812 105.003315523443 3.20075596226081 0.00145081018873326 B3GNT5 other 2.22843255902595e-11 1 7.95704893196361e-10 7.7026859530505 3.20075596226081 6.77160954540402e-70 232.257151337379 11.1272144870963 20.8728924572018 9.11816836409721e-71 -218.566714668098 120.648333080947 -1.8116016117807 0.0706234485985278 RMDN1 other 1.04777114496036e-65 1 1.41586918357701e-66 20.8728924572018 -1.8116016117807 2.77756091388201e-17 294.172696761668 39.9294066934923 7.36731950514086 6.51373346723159e-13 -116.15639685594 81.9045364226437 -1.41819247051896 0.156708214331266 MEX3C other 3.07698198039849e-13 1 7.94740620336926e-09 7.36731950514086 -1.41819247051896 1.00466989951324e-12 393.558680178954 61.7504005169283 6.3733785835294 3.95174875244008e-10 -157.711020185359 136.907277209446 -1.1519549829633 0.249846497241103 RNF152 other 9.49413055040015e-09 1 4.46863748925924e-06 6.3733785835294 -1.1519549829633 7.6983133600979e-06 389.971883669005 95.8562775245997 4.06829780729724 5.48310979213049e-05 -175.281110703993 219.943716024626 -0.796936206553712 0.425857475938344 MYO1D other 0.0472676440310011 1 0.464419399393453 4.06829780729724 -0.796936206553712 2.12698492164326e-08 18.0246142934252 6.09839285092342 2.95563351427841 0.00325578819923184 -29.6970282982687 13.0004613641661 -2.2843057231895 0.0227386075952137 FOXL1 other 0.000161374346005074 1 1 2.95563351427841 -2.2843057231895 1.34243108007903e-13 14.6583938850616 5.63776148674236 2.60003796179246 0.00958793145610352 -83.2963642001108 14.0342465021028 -5.93522168700899 5.38288249639219e-09 LRRC37A other 1.31450851361338e-09 7.41384406228096e-05 1 2.60003796179246 -5.93522168700899 5.37362114197373e-06 23.2888526288966 14.1982985390885 1.64025658178559 0.10153095004605 -80.1237456618627 29.9674545502396 -2.67369207242936 0.00772797678440427 FOXC2 other 0.0334507916087865 1 1 1.64025658178559 -2.67369207242936 0.0357993376592173 16.1821039947338 6.30310348119074 2.56732323101203 0.0105188168671663 8.28330116475103 16.1508141087211 0.512872051463846 0.608252122996051 BDNF other 1 1 1 2.56732323101203 0.512872051463846 4.97388659265713e-08 16.2969109566241 3.57964797810973 4.5526574278485 6.54605512031672e-06 -29.1851222897096 11.0535002360075 -2.64035117081167 0.00852074483575354 CCDC121 other 0.000368366041052187 1 0.0597982135240933 4.5526574278485 -2.64035117081167 1.49745469667896e-23 87.9200092996176 16.8292655233537 5.22423329631422 2.51452275921116e-07 -146.158831690721 36.1361655130051 -4.04466909025307 6.01551524469924e-05 ACSF3 other 1.89353146395054e-19 0.689678822804768 0.00251150533190011 5.22423329631422 -4.04466909025307 1.31670767048761e-08 76.6378972791529 60.4883299662783 1.26698649676521 0.205701267087586 -602.514303222489 117.025717621165 -5.14856320020993 3.67175944169226e-07 BOK other 0.000101004645403104 0.00474851820723054 1 1.26698649676521 -5.14856320020993 3.43969752036301e-06 3.54287239002875 1.27183837851633 2.78563098100697 0.00554159448911997 -25.8099159709838 7.49181770518273 -3.44508061816946 0.000618045503201828 ZNF843 other 0.021831760161744 1 1 2.78563098100697 -3.44508061816946 1.1097005072203e-47 231.205441590731 14.2622374112934 16.2110217999635 5.26275165454921e-48 416.942174685966 152.944431452403 2.72610235447324 0.00662832351369226 C8orf59 other 1.66865665270716e-43 1 8.04832610530211e-44 16.2110217999635 2.72610235447324 6.46702200106386e-07 2.1803975793296 0.585736390016129 3.72248953026388 0.000217928131328304 -4.75858662599415 1.68708877090751 -2.82059053918926 0.00496947313135769 PFN4 other 0.00439175464092247 1 1 3.72248953026388 -2.82059053918926 3.47739138150172e-11 46.0652728939159 6.49179561649251 7.09592162403979 4.30390528805846e-12 38.6237066659658 14.8977856346363 2.59258037490944 0.00979818153523769 CDK5R1 other 3.07018885072787e-07 1 5.15736970668045e-08 7.09592162403979 2.59258037490944 0.00824444010939178 5.87042508340056 21.1547476279489 0.277499178276405 0.781502453291882 -139.460512015851 48.838840095108 -2.85552465505462 0.00446093846273099 NCKAP5 other 1 1 1 0.277499178276405 -2.85552465505462 1.74655627003815e-26 143.31133816786 28.4807690602983 5.03186335539069 6.61424186724906e-07 -626.894469305122 76.2411737186647 -8.22251860416535 1.47680919465498e-15 RUFY1 other 2.3026597864183e-22 2.22717594645917e-11 0.00643433448845988 5.03186335539069 -8.22251860416535 0.210350435839157 4.48572029128588 47.9832729330081 0.0934850838030291 0.925552937879589 -418.650561446418 241.058807525175 -1.7367154751344 0.0830087277249272 BASP1 other 1 1 1 0.0934850838030291 -1.7367154751344 1.10355737428748e-06 14.8778096480723 6.26489688859815 2.37478922839885 0.0179236116801179 -111.040699179126 26.3659586028071 -4.21151761830133 2.9934014895825e-05 LRRC37A3 other 0.00733313875214032 0.350257908296048 1 2.37478922839885 -4.21151761830133 0.0102819549826629 46.0209786623645 15.5234158098913 2.96461675870594 0.00316726841278096 81.2689141717958 67.3821366770363 1.20608989532818 0.228321967779725 FKBP9P1 other 1 1 1 2.96461675870594 1.20608989532818 1.50891722908438e-12 126.282341986928 24.8933610283665 5.07293257198283 5.39223230195343e-07 -213.622678259142 55.7059124875541 -3.83482953101019 0.000140441127245484 VSIG10 other 1.4162697112186e-08 1 0.00527468163777084 5.07293257198283 -3.83482953101019 1.80040748064801e-11 149.476929223289 59.1876920148286 2.5254731876661 0.0118408766550485 -495.293086560526 132.11296669432 -3.74901191725203 0.000196797232891562 IRX5 other 1.61046449143964e-07 1 1 2.5254731876661 -3.74901191725203 0.0694955839039563 42.2698466093755 22.8898652257218 1.84666210100163 0.0653663211880259 -66.5166351619586 65.1747360659344 -1.02058925247763 0.307925491367041 METRNL other 1 1 1 1.84666210100163 -1.02058925247763 1.45009731877943e-56 369.916364439413 20.3840818229014 18.1473155206733 8.16841871129774e-58 8.88059304781849 234.998950126798 0.037789926478509 0.969869142113676 FAM91A1 other 2.21806885880501e-52 1 1.26071374390169e-53 18.1473155206733 0.037789926478509 3.05510957177807e-06 259.587163560524 54.3629461873432 4.77507533653431 2.31588382588078e-06 -33.3322690798006 121.652416458625 -0.273995947225077 0.784192318116104 WSB2 other 0.019506874615803 1 0.0218133097559711 4.77507533653431 -0.273995947225077 0.00129455018362596 10.4275635094492 6.77919262852914 1.5381718857739 0.124630430352832 -41.7812164976661 15.7452227590968 -2.65358052641884 0.00821426482588156 GRIN1 other 1 1 1 1.5381718857739 -2.65358052641884 5.37501839115565e-19 455.095443993797 47.7489590107698 9.53100242229679 5.21554737571221e-20 364.033677244893 145.740297244103 2.49782444614592 0.0127916474502372 SOX11 other 6.2156712675324e-15 1 7.172942305817e-16 9.53100242229679 2.49782444614592 2.74775037751433e-09 406.544462161164 70.033392720457 5.80500881606455 1.11713289377872e-08 47.0610848166085 153.572787914709 0.306441560745418 0.759390424399491 TYMS other 2.19682642682271e-05 1 0.000119354478371319 5.80500881606455 0.306441560745418 4.37830838501592e-06 38.2541302951254 12.0159304865107 3.18361780954627 0.00153939077006452 -78.4045921727533 28.7605841206763 -2.7261126493042 0.00661940365159216 PXMP2 other 0.027491398349515 1 1 3.18361780954627 -2.7261126493042 9.30065096408442e-22 192.387123056445 36.4881620226021 5.27259013313068 1.94236792238954e-07 -402.28452777611 71.536728062224 -5.62346837314387 2.9932564694856e-08 PNMA1 other 1.14044582121603e-17 0.000403101848745626 0.00195227399879372 5.27259013313068 -5.62346837314387 0.305832660780356 6.59815747882129 4.69767760130678 1.40455732359876 0.160722608451438 -3.91921835063801 14.8650609763557 -0.263653028862236 0.792146948462034 MAMSTR other 1 1 1 1.40455732359876 -0.263653028862236 6.49731590004979e-12 251.122018192216 42.6454575093819 5.88859946307224 6.89938136335032e-09 -243.943827485208 102.073515608318 -2.38988366405722 0.017200135596532 ANKLE2 essential 5.94374458536554e-08 1 7.43684317155531e-05 5.88859946307224 -2.38988366405722 0.151091442268789 23.4191808726977 14.4381455469904 1.62203523966964 0.105374117509176 -29.2134386678846 45.6872378559584 -0.639422299067149 0.522816913543309 FUT2 other 1 1 1 1.62203523966964 -0.639422299067149 1.98892067202615e-05 20.778917535585 11.9841962689171 1.73385991595267 0.083507409436875 -94.1651079125471 28.099398131541 -3.35114323345057 0.000860455625136122 GCNT4 other 0.117684436163787 1 1 1.73385991595267 -3.35114323345057 0.347629786243497 88.6428290476538 62.9629058341064 1.407857974046 0.159740134165142 98.8754914880958 295.602671640822 0.334487814129895 0.738139462800017 MUC20 other 1 1 1 1.407857974046 0.334487814129895 1.44108902225526e-11 106.731952349613 34.2778707821536 3.11372760075816 0.00194442647773743 -330.79683309386 66.3167991089092 -4.98813027074191 8.20989961974066e-07 THAP4 other 1.29597135771415e-07 0.0104684430051313 1 3.11372760075816 -4.98813027074191 0.171122161121517 -1.16137887049186 0.654790919644388 -1.77366367744165 0.0767062373552054 -3.8514236918628 4.70148240257954 -0.819193471775979 0.413052769454389 LY6H other 1 1 1 -1.77366367744165 -0.819193471775979 0.000315962460385684 -90.1209939953555 27.4734452866664 -3.28029459192341 0.00110451473487182 -234.087993384638 70.2022857221355 -3.33447822925838 0.000913816694958598 FIBIN other 1 1 1 -3.28029459192341 -3.33447822925838 1.14403052775487e-11 190.648953784739 38.6053949525383 4.93840184821638 1.06367264695472e-06 -333.458023615238 98.0269543415951 -3.40169727658002 0.000721343339024524 FAM89B other 1.03386038793207e-07 1 0.0102176394466471 4.93840184821638 -3.40169727658002 0.000977913036417702 -6.01988581731924 126.099597480385 -0.0477391358704033 0.961942905654352 -1042.96765134236 292.845643508721 -3.56149280162093 0.000403446618834123 DPP7 other 1 1 1 -0.0477391358704033 -3.56149280162093 1.05832608569581e-26 773.389703664907 85.8313895139603 9.0105695369072 3.76357746821776e-18 -891.401044810756 218.107885509493 -4.08697302588796 5.05185605763216e-05 SEC24C other 1.399318750507e-22 0.582630559126717 5.06840977644886e-14 9.0105695369072 -4.08697302588796 3.15019633743213e-35 145.40574500408 38.2947441020563 3.79701571099602 0.000163058088892402 -772.344732841694 76.9679847623237 -10.0346232946944 7.65366305187823e-22 SMCR8 other 4.50163056619051e-31 1.18486357706127e-17 1 3.79701571099602 -10.0346232946944 1.08694740830529e-16 -70.6116530855993 53.3031223741078 -1.32471888963674 0.185822660095683 -703.693794876896 85.8010051606084 -8.20146329940625 1.73201490990484e-15 MTHFR other 1.18335964342197e-12 2.61049287220858e-11 1 -1.32471888963674 -8.20146329940625 3.45543253625617e-08 5.50069977002835 1.13648752306026 4.84008812979875 1.70309092817183e-06 -12.9845478721683 5.45844369266152 -2.37880036934797 0.0177209712204772 C19orf18 other 0.000258639125338774 1 0.0161623329083507 4.84008812979875 -2.37880036934797 1.76860517475129e-17 98.0357321505728 34.5967910732141 2.83366546750271 0.00477353073149051 -413.331328359063 71.1335959290073 -5.81063452453009 1.06344836583307e-08 DEAF1 other 1.96757325691081e-13 0.000145245777805481 1 2.83366546750271 -5.81063452453009 2.11164550490893e-15 30.3113776396076 23.1137798146082 1.31139856322636 0.190276362134847 -366.509893915036 51.1702382363243 -7.16255985016816 2.58506894529611e-12 MTX3 other 2.20793653993278e-11 3.78324840144085e-08 1 1.31139856322636 -7.16255985016816 8.90578181342647e-12 49.4848817248452 19.7778967705799 2.50202952815767 0.0126424679619615 -182.519531374875 40.6822339222093 -4.48646777175216 8.85030715491387e-06 TMEM80 other 8.09232365072954e-08 0.107256872410401 1 2.50202952815767 -4.48646777175216 3.1462700631589e-06 -32.2195380916045 27.7686397879907 -1.16028506752926 0.24643891756296 -420.982858605187 83.1667164605316 -5.06191510885214 5.67924725102793e-07 SIX5 other 0.0200543253825748 0.00728988177141945 1 -1.16028506752926 -5.06191510885214 3.79136801461238e-11 31.1899606079668 19.2617089424294 1.61927276033446 0.105964961758947 -343.893765205959 57.6885687736536 -5.96121159731416 4.49156040013033e-09 FBXO46 other 3.34209090488081e-07 6.19880250821987e-05 1 1.61927276033446 -5.96121159731416 1.00963201397505e-11 143.606470387776 22.2815438351154 6.44508618659782 2.54519094962549e-10 -53.3539498413247 56.506174032071 -0.944214517355976 0.345478429721752 ZDHHC13 other 9.14928531064187e-08 1 2.895154705199e-06 6.44508618659782 -0.944214517355976 2.037656704868e-16 38.1077131939126 7.50621977606753 5.07681820287402 5.29418551513033e-07 -76.329299373393 17.1131575778652 -4.46026976763891 9.96768822776027e-06 SLC38A9 other 2.20026170991646e-12 0.120359835350205 0.0051835370378641 5.07681820287402 -4.46026976763891 6.48524411519257e-07 -14.3694593279727 7.34062183057179 -1.95752616871334 0.0508060916293277 -90.974277306883 16.8197223737837 -5.40878590532987 9.58926995861787e-08 ACER2 other 0.00440252537343385 0.00126990702061976 1 -1.95752616871334 -5.40878590532987 2.34184089593227e-36 173.675359468524 18.2719848042658 9.50500787566207 6.6531534901655e-20 -347.278226171645 47.6471757408911 -7.28853747932868 1.12934634571738e-12 WDR73 essential 3.36873812879857e-32 1.65867097795511e-08 9.13943694944034e-16 9.50500787566207 -7.28853747932868 3.63599771615913e-08 229.906601187495 41.5374602705626 5.53492196417286 4.88707787316412e-08 -39.8634457987081 99.0436001758873 -0.402483812461545 0.68748906309051 POLE other 0.000271936269191541 1 0.000507767391021752 5.53492196417286 -0.402483812461545 2.30561773848659e-07 64.6682153844438 17.0907376858419 3.7838165076991 0.000171522984417326 -60.6710063656287 33.265094386359 -1.82386394762517 0.0687191298136829 FAM109B other 0.00162292432612071 1 1 3.7838165076991 -1.82386394762517 0.0549133071582064 -48.7097192589837 21.983542455922 -2.21573567393194 0.0271212892265404 -83.5362801820666 40.5533356592025 -2.05991144314439 0.0398804031809422 SCN4B other 1 1 1 -2.21573567393194 -2.05991144314439 0.341884821313145 2.48290468929069 5.36751393287176 0.462580017554285 0.643849724391604 -8.82369906021174 10.0868854252909 -0.874769434585631 0.382083993630836 DSCAML1 other 1 1 1 0.462580017554285 -0.874769434585631 5.75552367829176e-06 69.0784894550442 28.3478415629877 2.43681654920903 0.0151367655550144 -188.218771858953 61.9012315180093 -3.04063048897813 0.00247452096236192 RHOG other 0.0357072689001221 1 1 2.43681654920903 -3.04063048897813 1.94960678228726e-11 235.031443385181 84.9151078277305 2.7678401334895 0.00583623325259772 -724.157346914547 174.783914211049 -4.14315785398958 3.97459719063241e-05 EPS8L2 other 1.74197365997367e-07 0.461331495916704 1 2.7678401334895 -4.14315785398958 0.651824927739261 -1.89043329439922 10.82947072405 -0.174563775328462 0.8614873605749 17.0541940253555 22.7706693823174 0.748954443939137 0.454208373841343 ZDHHC22 other 1 1 1 -0.174563775328462 0.748954443939137 0.022307154996734 122.664140844635 93.0421361716024 1.31837193224368 0.187948620300751 -557.320432962914 274.166103866178 -2.03278386753071 0.0425722775904099 ANO6 other 1 1 1 1.31837193224368 -2.03278386753071 9.31665816909536e-13 29.0729187376288 9.9645319090926 2.91764018649986 0.00367321079700404 -127.167283209122 22.2218228693932 -5.7226305851026 1.73723090574503e-08 ZBTB34 other 8.81169529633039e-09 0.000235620627746198 1 2.91764018649986 -5.7226305851026 2.01514514794049e-25 93.2830429807585 10.8408307861708 8.60478729174115 8.85808054349402e-17 -76.7731841729955 25.2730595184703 -3.03774792746749 0.00250187368401949 FAM210A other 2.61908414877826e-21 1 1.16917805093578e-12 8.60478729174115 -3.03774792746749 1.67862905333357e-10 859.094961804114 148.94988318009 5.76767798310666 1.35295636054441e-08 -27.3190512865879 305.942912012017 -0.08929460436565 0.928880828467047 TALDO1 other 1.4342206631682e-06 1 0.000144103381961585 5.76767798310666 -0.08929460436565 4.67224022810197e-17 263.837448617239 49.3724867148405 5.34381527390101 1.34438236494576e-07 -599.89236417326 116.074586621624 -5.16816283075612 3.33325636122481e-07 ULK1 other 5.14226759504902e-13 0.00431623366215 0.00136212821216304 5.34381527390101 -5.16816283075612 0.000114430415486746 80.9296802497209 19.3385227003209 4.18489465321866 3.33106227498827e-05 16.4458770228102 46.1361789394044 0.356463786140815 0.72163276073645 RIMKLA other 0.617123230720019 1 0.287675794900141 4.18489465321866 0.356463786140815 1.0383609996912e-07 88.0817103028197 16.034872697869 5.49313436797822 6.19372246911182e-08 -150.934564101246 134.91356812064 -1.11875007238916 0.263764304332049 CLVS1 other 0.000750319658376858 1 0.000640492840530854 5.49313436797822 -1.11875007238916 0.0251767424967743 6.16355149498615 5.92071390438216 1.04101491720859 0.298330206918549 -39.0772245958644 19.3101191568812 -2.02366563760633 0.04349202868979 B3GNT8 other 1 1 1 1.04101491720859 -2.02366563760633 4.15343152766569e-08 92.0125078546769 17.2700977178287 5.32785102655719 1.46056529990727e-07 -33.6963026606379 40.5548265406426 -0.830882672543764 0.406406450226665 PUS1 other 0.000308932237027774 1 0.00147648546167626 5.32785102655719 -0.830882672543764 3.08606100645428e-12 160.202459087332 48.9667698593363 3.27165666731817 0.00113892246649917 -343.227111937974 109.568194247989 -3.13254329227274 0.00182894112999715 CHD9 other 2.86170437128505e-08 1 1 3.27165666731817 -3.13254329227274 4.23173173343522e-13 118.643912674389 46.8571483486752 2.53203442496184 0.0116221012577336 -469.674084867917 96.2445361372998 -4.88000777725078 1.39774785777388e-06 GATD1 other 4.05272948111091e-09 0.0176283959822442 1 2.53203442496184 -4.88000777725078 0.613910099660541 23.314844849763 33.1870014329398 0.702529419443779 0.482667710524799 -98.7155429988216 195.625083844069 -0.504615977966847 0.614045264055465 TRIM72 other 1 1 1 0.702529419443779 -0.504615977966847 7.8264333521395e-10 352.612807263136 68.5536064345448 5.14360696106939 3.85515017951663e-07 -360.456174027837 159.204512879517 -2.26410776622031 0.0239882850508627 MAN1B1 other 6.44252685098934e-06 1 0.00380965940739833 5.14360696106939 -2.26410776622031 0.881952219955227 -0.869697356103747 1.83415915542822 -0.474166788378134 0.635572288974974 -1.36066916620852 3.94096254989281 -0.345263155633267 0.730030741471828 KCNA3 other 1 1 1 -0.474166788378134 -0.345263155633267 1.32507362359117e-08 15.4784940760548 3.24044779793663 4.77665280888364 2.29643428590376e-06 -9.74880207129034 6.81239848806904 -1.43103814146574 0.152994531080846 CLDN22 other 0.000101606645456971 1 0.0216370038417853 4.77665280888364 -1.43103814146574 0.336747863288966 1.4716838085403 3.84911022379696 0.382343898452603 0.702355622901762 -9.50120848994544 8.36515666374994 -1.13580759713904 0.256537231375912 KCNA2 other 1 1 1 0.382343898452603 -1.13580759713904 1.76295964225802e-48 174.5965784806 14.1832476515924 12.31005639678 8.22599761794776e-31 -123.040567492074 28.6099819796912 -4.30061674206625 2.02735079990014e-05 TOP3A essential 2.65413574141945e-44 0.240281616804164 1.21317012869494e-26 12.31005639678 -4.30061674206625 3.27066802295524e-24 168.471278382105 16.482457530926 10.2212475333852 1.58720438440046e-22 -96.7881821257722 56.037420118917 -1.72720624754633 0.0847067158150615 CASKIN2 other 4.17664306531384e-20 1 2.23081576227484e-18 10.2212475333852 -1.72720624754633 0.000664756945785748 87.4588151243858 48.090342804121 1.81863571820684 0.0695157336611223 -576.071298514612 179.659301984704 -3.20646519356764 0.00142256088724943 ZBTB38 other 1 1 1 1.81863571820684 -3.20646519356764 4.97909134513153e-05 6.92696150869548 1.57055329773026 4.41052304223372 1.25300128172171e-05 15.2887627640907 11.2024474920034 1.364769866139 0.172913373060112 C8orf31 other 0.281567615567188 1 0.111993254560286 4.41052304223372 1.364769866139 0.0255153617852924 -5.20860792396364 3.1976374726074 -1.62889257102571 0.103920048716381 -18.0221269724577 6.91245506410011 -2.60719625738412 0.00938154795366698 RPL13AP3 other 1 1 1 -1.62889257102571 -2.60719625738412 1.1799685039185e-40 41.3391523407907 14.6450946429556 2.82273029629583 0.00494370399691721 -304.782801749305 26.5099523514495 -11.4969200136129 2.0292684191887e-27 CCDC71 other 1.73278374800431e-36 3.16870263656316e-23 1 2.82273029629583 -11.4969200136129 0.77759181817097 -29.0470721222293 50.2565161711572 -0.577976237415751 0.563518448893713 -75.6447107953975 131.712419839744 -0.574317219951128 0.56598968649332 C10orf71 other 1 1 1 -0.577976237415751 -0.574317219951128 0.210546205142213 1.18877157027074 7.64133857077816 0.155571116141459 0.876431815067074 -29.5084630453044 19.0610563893228 -1.54810218503072 0.122209585728472 LRRN4CL other 1 1 1 0.155571116141459 -1.54810218503072 1.47188365156147e-50 102.844247951323 10.9021554605198 9.43338666594467 1.19700979446909e-19 -177.482197325018 20.21880654061 -8.77807485662127 2.2307488749987e-17 TIMM22 essential 2.22946216702016e-46 3.40166895948552e-13 1.63954431548431e-15 9.43338666594467 -8.77807485662127 3.60236237927206e-16 -9.10772933016528 24.1924364422586 -0.376470115025545 0.706714215528283 -358.859348791811 44.4851527446989 -8.06694653497788 4.62895722541791e-15 HIC1 other 3.86137223434172e-12 6.95176796113262e-11 1 -0.376470115025545 -8.06694653497788 5.34557182689143e-08 102.137871759546 17.3816767580229 5.87618059991834 7.30064008790435e-09 93.2027601761886 57.8545209594919 1.61098490887941 0.107759859152628 PPFIA3 other 0.000395144669443815 1 7.85913905462903e-05 5.87618059991834 1.61098490887941 1.70119789443263e-12 255.935607550473 33.9047850846871 7.54865742139934 1.87464307675674e-13 43.8492794304242 140.120975681228 0.31293872467874 0.754447592450229 MAGEF1 other 1.59385230729393e-08 1 2.32062066471716e-09 7.54865742139934 0.31293872467874 1.35098211180447e-05 22.3316922984816 4.66964156493086 4.78231401446167 2.23117745941156e-06 10.2418698816634 14.8180270123399 0.691176353851585 0.489747938992592 UMODL1 other 0.0812480642039211 1 0.0210310787324133 4.78231401446167 0.691176353851585 0.6156187914173 -41.0451134876927 73.1676134482995 -0.560973790906756 0.575047240505949 -219.150114512967 235.790855693911 -0.929425841676634 0.353082186313203 SAMD9L other 1 1 1 -0.560973790906756 -0.929425841676634 1.93642375405036e-06 238.801141706554 47.5692854665747 5.02006997507564 7.04153973327075e-07 -268.896637730987 331.400033608505 -0.811395927764582 0.417498495269816 ZFAS1 other 0.012609991486376 1 0.00683944754292588 5.02006997507564 -0.811395927764582 1.68718395435692e-23 436.491155528449 48.4342662877543 9.01203195554151 3.6288095599838e-18 -674.129903643596 171.896721038168 -3.92171473412754 9.94288628109975e-05 PAWR other 2.13125077114366e-19 1 4.88800647729818e-14 9.01203195554151 -3.92171473412754 7.84645834017054e-13 66.386202338644 50.0605049271084 1.32611931172702 0.185369234778854 -696.721107850665 113.950729444464 -6.1142312229798 1.87923513477578e-09 TGIF1 other 7.43922715231569e-09 2.61645907814832e-05 1 1.32611931172702 -6.1142312229798 4.55149906989045e-65 121.506608220628 12.6908709242105 9.57433173391031 4.04630192292621e-20 -293.210651598976 25.6513142769288 -11.4306287948253 3.61024086397646e-27 MIEF2 other 7.02660426409688e-61 5.63594701275366e-23 5.57094848748481e-16 9.57433173391031 -11.4306287948253 3.88510796523167e-06 4.44820673215443 5.28213857856601 0.842122308226532 0.400086855367214 -57.0169818971146 13.0081642785283 -4.3831689603758 1.40237885606095e-05 NAP1L5 other 0.0245383419084032 0.167808653916253 1 0.842122308226532 -4.3831689603758 0.393451310180454 -1.9976691169 3.10112495565914 -0.644175628348843 0.519745040851874 -18.7374025631427 14.5367425894716 -1.28896844996853 0.197981065649762 NIM1K other 1 1 1 -0.644175628348843 -1.28896844996853 0.318655642050045 1.55509333329219 1.85428048779947 0.838650540478729 0.402038589896275 15.9510518705669 11.1373891679763 1.43220746173003 0.152666268895063 CD19 other 1 1 1 0.838650540478729 1.43220746173003 0.128503546069954 1.32133716490075 1.51323336352492 0.873187967401691 0.382956071583037 31.7847382995043 16.9786032930756 1.872046702008 0.0617506177386016 ERICH5 other 1 1 1 0.873187967401691 1.872046702008 1.58006808934021e-07 129.589911594254 27.8012662421911 4.66129529731953 3.95718542223793e-06 -169.53736293224 80.8323823760329 -2.09739411296268 0.0364196121563934 NR2C2 other 0.00112769459536211 1 0.0366593657516122 4.66129529731953 -2.09739411296268 0.253675297097273 -9.89409690933071 6.82925947451575 -1.44878034672014 0.14797192811136 -25.4026946871597 20.4391830552506 -1.24284295602676 0.214458194617835 GPR4 other 1 1 1 -1.44878034672014 -1.24284295602676 4.24980470383549e-24 51.126277197019 16.9714422132714 3.01248865915704 0.00271169056686552 -270.545705552655 33.3502354305445 -8.11225774151117 3.32111769240869e-15 ACOT4 other 5.4172260559791e-20 4.99562523292114e-11 1 3.01248865915704 -8.11225774151117 0.402297408540886 -410.429702933927 304.084179714735 -1.34972395906606 0.177671124698818 -329.746168941727 679.835985386663 -0.485037826813743 0.627846581322394 CAVIN1 other 1 1 1 -1.34972395906606 -0.485037826813743 5.05593733585201e-32 247.087929204684 34.7222674015022 7.11612310185694 3.68529674835827e-12 -381.177999444622 62.7777496658269 -6.07186465704292 2.43543865020863e-09 ARIH2 other 7.04898783364487e-28 3.38233719740974e-05 4.4241987464041e-08 7.11612310185694 -6.07186465704292 1.54949659612595e-05 6.26622534339148 1.87259458127574 3.34627975860236 0.000875910980712418 24.2103262752356 6.36319710314907 3.80474247187065 0.000158149565411318 ZBED2 other 0.0926753914142929 1 1 3.34627975860236 3.80474247187065 0.00477525771003312 55.8074761051165 90.4790360182602 0.61680007392932 0.537629477535128 -435.913416431928 203.606847962144 -2.14095655816536 0.0327296374842323 IRX3 other 1 1 1 0.61680007392932 -2.14095655816536 2.34142346414007e-10 221.496554195862 40.0797553960229 5.52639485963132 5.08446674515593e-08 -36.373336765301 82.295755967011 -0.441983141632256 0.658677701680233 SLC25A22 other 1.98646366697644e-06 1 0.00052792018214954 5.52639485963132 -0.441983141632256 3.30699726000455e-12 191.637600470742 30.2213445666771 6.34113416257616 4.84223984856126e-10 -394.495013311993 181.407055865722 -2.17463985306061 0.0300928861947569 RABEP2 other 3.06393296139422e-08 1 5.45672008534369e-06 6.34113416257616 -2.17463985306061 3.15218405057786e-10 207.8782240182 50.9170297701487 4.08268559569578 5.11780051450377e-05 -433.428947087465 119.46653190614 -3.62803657369071 0.000312388290231216 ATOX1 other 2.65224766015621e-06 1 0.434245373655645 4.08268559569578 -3.62803657369071 4.67243295017921e-09 723.014506059279 120.522570225184 5.99899674150992 3.67577773045442e-09 -1017.20768284308 500.049138547897 -2.03421544889962 0.0424263230967482 TBL1XR1 other 3.68982030075652e-05 1 3.9992461707344e-05 5.99899674150992 -2.03421544889962 2.90881510977451e-16 107.666860474827 13.2443428799856 8.1292716030125 3.12468838297802e-15 -518.034654367768 157.878591465224 -3.28122166254489 0.00110227054271893 SAMD12 other 3.1269762430076e-12 1 4.01116247722888e-11 8.1292716030125 -3.28122166254489 9.5231444831517e-05 115.198443796286 48.0324478692996 2.39834630351864 0.0168063376899371 703.219233168624 172.577203410696 4.07480953028955 5.29409827733341e-05 CD163 other 0.519106605776599 0.609827180566035 1 2.39834630351864 4.07480953028955 4.43539579771043e-28 471.706963263335 56.5602289442201 8.33990547896356 6.22148912687059e-16 -464.530373731897 115.514332289039 -4.02140898472713 6.60909174776724e-05 C18orf32 other 5.9585107146442e-24 0.755154823099884 8.08918016275714e-12 8.33990547896356 -4.02140898472713 6.97547075767597e-11 64.9603792362697 22.6732322620239 2.86506919196845 0.00433063277842853 -181.595941718762 46.5391688811465 -3.90200225067467 0.000107381405185142 PIDD1 other 6.06726446502655e-07 1 1 2.86506919196845 -3.90200225067467 2.7630682049884e-08 2.52453757388932 1.41492408427529 1.78422121861213 0.0749629424898449 -26.1180992215867 5.15394536639952 -5.06759334157096 5.58416261406819e-07 ZNF491 other 0.000208307711974075 0.00717062321272496 1 1.78422121861213 -5.06759334157096 6.4943893715209e-05 802.182360178856 686.185021487244 1.16904673675359 0.242897741503671 -4243.27198285463 1408.46616969544 -3.01269002703286 0.00271014653981229 RPLP2 essential 0.36206220746229 1 1 1.16904673675359 -3.01269002703286 0.00537832996831067 -223.977225678757 421.288550998509 -0.531648024015609 0.595188834171705 -2755.70608410361 863.430595158169 -3.19157799081558 0.00149743156954972 JUN og 1 1 1 -0.531648024015609 -3.19157799081558 2.04849432103495e-15 81.5325163473655 22.6639423057176 3.59745516678255 0.000351034859028967 -369.158097997544 59.6733466624905 -6.18631463868592 1.22191267623894e-09 CSTF2T other 2.14292990923466e-11 1.70835611264966e-05 1 3.59745516678255 -6.18631463868592 0.289047886289335 45.1342481350274 28.6678580763678 1.57438508362903 0.11597874398068 33.6450258405424 169.935642066282 0.197986869802272 0.843129161859615 PGBD5 other 1 1 1 1.57438508362903 0.197986869802272 2.77293685080383e-33 504.149687672599 38.3630032122774 13.1415594572443 2.58796753040953e-34 66.4992360811698 397.839337682228 0.167150982274874 0.867315491114299 GBA other 3.90679072909751e-29 1 3.86047116511189e-30 13.1415594572443 0.167150982274874 8.17281693120747e-11 9.98365775217291 3.62445318049103 2.75452799498444 0.00607591527767256 -33.1792749098446 6.79335741561541 -4.88407614673382 1.37107730789516e-06 CASC2 other 7.08256315258439e-07 0.0173057377802527 1 2.75452799498444 -4.88407614673382 1.38594907055796e-32 256.413500025932 21.3194850151759 12.0271901428862 1.12440035700685e-29 -183.772536215759 71.2837137738411 -2.57804379831846 0.0102009611443051 ACAD9 other 1.94226902747992e-28 1 1.65061972408605e-25 12.0271901428862 -2.57804379831846 9.16502552272925e-21 69.5353809549564 20.7288024464229 3.3545295795395 0.000851470878065763 -245.823809008814 39.4825973250065 -6.22613064143884 9.68433525330692e-10 IL17RA other 1.10282752115001e-16 1.35725958575097e-05 1 3.3545295795395 -6.22613064143884 5.63434922806542e-08 319.451625769483 195.973823841224 1.63007293274177 0.103665982092918 -1579.73686898719 402.25666894909 -3.9271862741625 9.70182421095018e-05 PNPLA2 other 0.000415927660015789 1 1 1.63007293274177 -3.9271862741625 9.3668096841647e-14 169.556730693483 60.0033096599941 2.82578963817609 0.00489037718171255 -475.720383045353 96.5861670477219 -4.92534694756347 1.11998114030263e-06 AGTRAP other 9.22068745309173e-10 0.0141935209910552 1 2.82578963817609 -4.92534694756347 2.39280724531034e-18 70.3714841635318 7.5585933369902 9.31012967970486 3.14388357464234e-19 36.4477716518372 27.242529006055 1.33789970981535 0.181489160988724 CD163L1 other 2.72516817168394e-14 1 4.28637086566737e-15 9.31012967970486 1.33789970981535 0.0762880074631451 16.7868807451139 10.1415442752045 1.65525883332748 0.0984584453940738 -40.4961289483685 35.5036161207037 -1.14061984026336 0.254538495371905 SRRM3 other 1 1 1 1.65525883332748 -1.14061984026336 4.23868341360548e-12 49.4711297817632 17.284400547205 2.86218371569519 0.0043708727261903 -294.916734565589 52.1665756599946 -5.65336579666958 2.55357550258571e-08 THAP5 other 3.90721837066153e-08 0.000344579478318916 1 2.86218371569519 -5.65336579666958 1.09863835425473e-10 -157.340123662691 130.164184802228 -1.20878200022344 0.227271739410168 -1715.84858359924 267.085404979337 -6.4243442419925 2.89351869179776e-10 CRACR2B other 9.45707895342472e-07 4.10098404188497e-06 1 -1.20878200022344 -6.4243442419925 4.33697240964522e-11 6.45487821838689 1.17700391890392 5.4841603453606 6.40994897729876e-08 -12.2679083673292 3.71103974436416 -3.30578738370023 0.00101048960381818 DNAJC28 other 3.81003026187333e-07 1 0.000662147729354961 5.4841603453606 -3.30578738370023 0.339055720443766 12.3086460744764 32.5956892204859 0.377615763582032 0.705866372540662 -193.403574357109 134.795611176337 -1.43479133088467 0.151933053421251 NAALADL2 other 1 1 1 0.377615763582032 -1.43479133088467 2.70370158336533e-17 715.034607601366 271.778450030078 2.63094666822271 0.00875614640882636 -3346.62392383858 558.04020927427 -5.99710176474712 3.6641448329392e-09 CD151 other 2.99651246484379e-13 5.06677947498833e-05 1 2.63094666822271 -5.99710176474712 4.75762692275272e-11 220.539751739109 134.593239270439 1.63856485611418 0.10188210867662 -1376.30907643752 276.359068944081 -4.98014804325458 8.54496566563735e-07 POLR2L essential 4.17005999779276e-07 0.0108870561178502 1 1.63856485611418 -4.98014804325458 1.15099096299781e-11 469.884796654824 65.2439544607906 7.20196684180461 2.10780958409902e-12 210.419147281934 235.456691103903 0.8936639103158 0.371917547615162 FAM20C other 1.03992033506852e-07 1 2.54518007279956e-08 7.20196684180461 0.8936639103158 0.691832482622981 -4.08843627018776 8.30771191830072 -0.492125426398273 0.622830311372275 -21.1740378448534 27.6753347466127 -0.765086964212602 0.444553379359524 NECTIN3 other 1 1 1 -0.492125426398273 -0.765086964212602 0.289723996903468 3.38475157914581 2.84483344055468 1.18978901572735 0.234670190690664 16.0363759781276 13.3532727448225 1.20093225717609 0.230322125954466 ANXA2R other 1 1 1 1.18978901572735 1.20093225717609 9.73401338486979e-40 751.106451858853 96.2525863173469 7.80349370958654 3.2981529861857e-14 -1483.74883019348 194.678054131213 -7.62155157557424 1.18666658258718e-13 FLII other 1.42428083847415e-35 1.76053854192634e-09 4.15435350139951e-10 7.80349370958654 -7.62155157557424 2.77205566225564e-20 298.016660975769 40.0963226340148 7.43251853033908 4.20985559737167e-13 -612.768470560957 148.555466275668 -4.12484633466041 4.29616029287161e-05 SOX12 other 3.30179549931269e-16 0.497710169929176 5.16002000569846e-09 7.43251853033908 -4.12484633466041 1.00810820067626e-11 263.0296884825 94.3227479688262 2.78861350147933 0.00547839942873963 -1160.38491304869 218.099745588331 -5.3204322174632 1.51418381619883e-07 HNRNPA0 other 9.13648462272893e-08 0.00198842618743231 1 2.78861350147933 -5.3204322174632 0.789120328147083 -91.5190307027456 160.193738078318 -0.571302173234777 0.568037004356316 -228.940890880337 422.166369501655 -0.542300162731081 0.587839680839882 MYOZ1 other 1 1 1 -0.571302173234777 -0.542300162731081 0.0137305107398566 2.70706886569442 1.25336625373319 2.1598386406458 0.0312229483706272 24.2278581525464 12.33104778274 1.96478503525536 0.0499495204525183 KCNJ10 other 1 1 1 2.1598386406458 1.96478503525536 9.14896102798443e-16 176.560110511879 53.595605258852 3.29430201709901 0.00105074006542657 -554.205967581068 110.01048008982 -5.03775610404186 6.41561370361239e-07 CHID1 other 9.68600504032711e-12 0.00821711803158674 1 3.29430201709901 -5.03775610404186 2.67166220018553e-08 4.41907368842922 10.6600056917876 0.414547028978949 0.678638464230157 149.01457219748 25.9522607447767 5.7418724966946 1.56525165060012e-08 PCDHB9 other 0.000201523479759994 0.000212733351833063 1 0.414547028978949 5.7418724966946 1.03811975990682e-14 5.21550279179763 4.16678794265267 1.25168423821379 0.211222883614553 -54.6519220795728 8.04741717574328 -6.79123759661745 2.92069904474775e-11 ZNF620 other 1.05898596708095e-10 4.2122321623352e-07 1 1.25168423821379 -6.79123759661745 0.0190707920926394 72.4146540840583 30.7443045721907 2.35538435790673 0.0188576237193675 -28.268619857765 59.3734786895239 -0.47611527034802 0.634183411660659 ZNF518A other 1 1 1 2.35538435790673 -0.47611527034802 3.01947197735997e-23 111.696599101766 11.4665751419607 9.74106023105578 9.10188386462926e-21 -33.7036926080686 27.5564766590347 -1.22307699293692 0.221833113765586 SVBP other 3.7972879587279e-19 1 1.26079295292845e-16 9.74106023105578 -1.22307699293692 2.12414288527527e-24 8.11114548277227 7.76021221153739 1.04522212301271 0.296383681946832 -140.340455557201 14.9827765618958 -9.36678558726661 1.9612889108755e-19 ZNF619 other 2.72038979317204e-20 3.01430492712456e-15 1 1.04522212301271 -9.36678558726661 0.267223797691154 1.33317832352868 1.87739438944239 0.710121608451518 0.477934138746144 -6.8146579706441 5.56104315947309 -1.22542799529177 0.220946234531989 CCDC184 other 1 1 1 0.710121608451518 -1.22542799529177 1.89962901625324e-07 217.632960285209 47.0447771640113 4.62608122313939 4.66998210483939e-06 -129.648000088082 105.462715820328 -1.22932544529725 0.219485192556704 AP3S1 other 0.00134664700962192 1 0.0430478950424095 4.62608122313939 -1.22932544529725 1.73221290463476e-13 1154.42803970223 184.064061128186 6.27188182541654 7.37137111067357e-10 -2018.12191387722 596.738343131616 -3.38192096604073 0.000772548048024067 GRB2 essential 1.6889075820189e-09 1 8.24782713573265e-06 6.27188182541654 -3.38192096604073 8.02584167405206e-11 294.632008579583 44.454815619541 6.62767361586068 8.36573752499622e-11 -544.370129309777 307.368617566184 -1.77106606920454 0.0771211400799497 ZBTB41 other 6.96000989973795e-07 1 9.65740739885563e-07 6.62767361586068 -1.77106606920454 1.83508271958886e-26 450.961178153694 45.1581431272064 9.98626486663496 1.18865517944687e-21 -342.691753362065 117.767457648842 -2.90990193898809 0.0037656122569331 UBE2N essential 2.4182720078742e-22 1 1.65864943740016e-17 9.98626486663496 -2.90990193898809 2.36166641943836e-10 89.5775188784043 13.5268581520173 6.62219695599048 8.65724504247408e-11 19.9507220901944 33.2777290566665 0.599521741889947 0.549079772848267 ARL6IP6 other 2.00340162360956e-06 1 9.98959505451084e-07 6.62219695599048 0.599521741889947 0.144452232411084 11.8380757691106 12.7616695933234 0.927627508496538 0.354014480458347 66.8739460434151 34.3663300670687 1.94591467616429 0.0521824384804553 ZNF354C other 1 1 1 0.927627508496538 1.94591467616429 9.77944935848849e-06 14.7982758290962 10.7917919727767 1.37125288056203 0.170900366661722 -99.4001331130204 25.0595392033405 -3.96655869473331 8.33766280471993e-05 MAMDC4 other 0.0595275082451195 0.945240832171099 1 1.37125288056203 -3.96655869473331 1.15416128489851e-48 106.928652258096 11.0387280294353 9.68668237617289 1.59815604222517e-20 -104.571822757164 23.9092610677681 -4.37369529994118 1.47433879099543e-05 CENPBD1 other 1.73909022408507e-44 0.176212972299774 2.20817220354251e-16 9.68668237617289 -4.37369529994118 1.21753510891384e-23 155.780777167656 52.1075016878544 2.98960364864253 0.00292162728953453 -777.55745969253 107.243482927578 -7.25039357606113 1.46028963530944e-12 BET1L other 1.54115594086314e-19 2.14166077914483e-08 1 2.98960364864253 -7.25039357606113 4.43951273848511e-05 56.5885959630945 12.8114331270299 4.41703870300838 1.21193318228709e-05 76.2431849464085 136.611737294696 0.558101276334244 0.57700913598455 RPS27 essential 0.253229806603191 1 0.108480139146518 4.41703870300838 0.558101276334244 1.64123585680848e-23 227.470341362193 29.6257897510038 7.67811907375349 7.58194526324812e-14 -333.174391776937 64.3520625224596 -5.17736928261865 3.17642342810089e-07 IMP3 essential 2.07370150507751e-19 0.00411632712047595 9.46909143927058e-10 7.67811907375349 -5.17736928261865 1.2124712088566e-17 78.8204960407233 18.8196165575851 4.18820945684758 3.28154080634187e-05 -376.666625143877 55.7445436398889 -6.75701334245648 3.64516570635062e-11 ASB8 other 1.35578530574345e-13 5.24867410057426e-07 0.283689202708255 4.18820945684758 -6.75701334245648 0.000210665215344282 40.2654503150724 32.8983227094586 1.2239362678358 0.221526304895499 -219.059401611854 70.4832648059594 -3.10796331888037 0.00198606619814474 ODF3B other 1 1 1 1.2239362678358 -3.10796331888037 0.424425719778311 2.73638485184096 5.31205070082933 0.515127773801886 0.606679323177341 -16.7797080894152 15.8976376968767 -1.05548436876957 0.291686566324939 DPY19L2 other 1 1 1 0.515127773801886 -1.05548436876957 1.00338261648879e-06 88.3035093363226 27.1116439947471 3.25703263709982 0.00119573598239941 -126.311299106456 59.8800964701676 -2.10940373433407 0.0353643193564919 LRRC75B other 0.0066935654345967 1 1 3.25703263709982 -2.10940373433407 2.32919299693055e-10 99.131962173939 27.2128196202664 3.64284052726796 0.000295454371732574 -251.709052325795 59.5447437567083 -4.22722538456532 2.77490064045604e-05 DMAP1 essential 1.97655317719526e-06 0.32546809611909 1 3.64284052726796 -4.22722538456532 0.684259244423852 -0.499439630207827 15.9450839261619 -0.0313224836269674 0.975024041225239 -29.6777078528398 36.4299923988832 -0.814650399261396 0.415634926455854 ADAMTSL1 other 1 1 1 -0.0313224836269674 -0.814650399261396 1.75831141562911e-20 322.915175619391 193.524212142944 1.6686034891638 0.0957967795380792 -2754.42989354901 350.309627068812 -7.86284384073736 2.1748594973635e-14 IMPDH2 essential 2.10188546624303e-16 3.24793517336265e-10 1 1.6686034891638 -7.86284384073736 0.0341030506783244 37.4642944463381 16.6343076503694 2.25223046451869 0.024715374912724 -1.48996564862185 31.048923340086 -0.0479876752021934 0.961744108170213 ALS2CL other 1 1 1 2.25223046451869 -0.0479876752021934 6.05380525414325e-12 157.491282316903 21.4676792127222 7.33620438224036 8.19796122926736e-13 -32.8406825698209 83.0891038126176 -0.395246561376846 0.692818475245293 MLF1 other 5.54679752856384e-08 1 9.98019800051008e-09 7.33620438224036 -0.395246561376846 1.26604271283246e-19 230.421284086702 49.0231359844401 4.70025589876253 3.33034878678772e-06 -468.036021683552 88.7396791041736 -5.27425866769378 1.95742917991793e-07 NDUFAF3 essential 1.48823320893456e-15 0.00255601102313684 0.0309955561586333 4.70025589876253 -5.27425866769378 2.98466919226581e-07 66.7990103097392 16.1568428798241 4.13440984767852 4.12752578442666e-05 -102.148353660702 40.2840422705409 -2.53570267290185 0.0115040932915683 C2orf69 other 0.00208240369544386 1 0.353316207146922 4.13440984767852 -2.53570267290185 0.000137156328912288 -9.48818255417165 11.3001319733904 -0.839652366584251 0.40147421668086 -158.522286901048 37.2975934152381 -4.25020148448193 2.51546130009243e-05 GRAMD1C other 0.732551952720531 0.295918867342873 1 -0.839652366584251 -4.25020148448193 3.25648064151151e-13 214.295355258116 35.828846275333 5.98108444830533 4.01034574178408e-09 -238.917523822807 92.7583597517984 -2.5756980229286 0.0102656386842739 STAP2 other 3.13859604228879e-09 1 4.35563651015169e-05 5.98108444830533 -2.5756980229286 2.17145940053226e-05 3.71907230141965 1.68364397334733 2.20894224687277 0.0276064996253529 -17.7563555707216 5.41493747579207 -3.2791432311274 0.00110972357990571 TSSK6 other 0.127746956533313 1 1 2.20894224687277 -3.2791432311274 7.63446945625499e-15 67.3022259687333 9.08437224547101 7.40857201247853 5.46071391129524e-13 356.117616162494 107.954215510636 3.29878378975769 0.00104011566987937 BOLA1 other 7.83907323768262e-11 1 6.67899918490521e-09 7.40857201247853 3.29878378975769 2.10812294106927e-34 135.921142523553 21.4244780118424 6.34419855869639 4.72821796249124e-10 -244.695242465442 40.856315083479 -5.98916573767047 3.84805338767881e-09 DDX10 other 2.9945886377889e-30 5.31839458711088e-05 5.33059293091263e-06 6.34419855869639 -5.98916573767047 9.61935381998766e-07 -0.365021549111997 0.936534534644378 -0.389757703116206 0.696868266942504 -8.58512592868789 1.77587294248957 -4.83431315567685 1.74099269809268e-06 GOLGA8O other 0.00643438577018974 0.0218581633245537 1 -0.389757703116206 -4.83431315567685 1.8121922085558e-68 74.1477450017785 3.63412308181033 20.4032013590585 1.16063395748806e-68 -25.5862655320461 34.069120006513 -0.751010461296176 0.4529809354705 PPP1R42 other 2.80164915442726e-64 1 1.80025933145973e-64 20.4032013590585 -0.751010461296176 3.87858682926914e-21 194.90321166839 50.5902162340704 3.85258704502494 0.000130940478937102 -711.393910956852 107.416227471885 -6.62277877095481 8.54459064771816e-11 NDUFV2 other 4.70007151970834e-17 1.22290181350142e-06 1 3.85258704502494 -6.62277877095481 4.45636769162783e-30 169.120022981274 62.9080488185469 2.68836859761915 0.00741006077249458 -1070.77940295134 113.873581384092 -9.40322935255401 1.67118067273194e-19 DALRD3 other 6.099430459531e-26 2.56944028432536e-15 1 2.68836859761915 -9.40322935255401 0.00375139006999297 5.75910872188643 1.78887514260275 3.2194022851182 0.00136077354060272 10.2233727781978 5.4193151032759 1.88646952306168 0.0597611296110666 ZNF114 other 1 1 1 3.2194022851182 1.88646952306168 0.00171530945763834 74.1201636321087 33.6208349478733 2.20459021160619 0.0279030113783443 258.701703859667 73.6582688817145 3.51218821440275 0.000481575283265743 ZNF518B other 1 1 1 2.20459021160619 3.51218821440275 6.52396911336543e-05 -1.37338818062433 2.86842709302735 -0.478794871224999 0.632277303347211 -28.8497880340091 6.79720110669851 -4.2443628754162 2.57816035451335e-05 ZNF366 other 0.363580798687855 0.302959623258864 1 -0.478794871224999 -4.2443628754162 6.33465489358405e-12 103.715121487311 18.7630396592967 5.52762896474091 5.04282370847319e-08 -51.373780078707 34.6708036109472 -1.48175913818409 0.138983390999593 LCORL other 5.7993765550762e-08 1 0.000523697242124941 5.52762896474091 -1.48175913818409 1.37067274335576e-07 42.2600871838053 15.5664812807471 2.71481309241499 0.00685472049279422 -105.743576554139 31.9262705855312 -3.31211803366917 0.000991205642606072 PARD6G other 0.000982361155163076 1 1 2.71481309241499 -3.31211803366917 2.88867763995111e-19 2.51311301195555 1.35928772933228 1.8488455076322 0.0650245070983777 34.6770650323017 3.65001934911662 9.50051539882776 6.6662334653932e-20 ZNF454 other 3.36530945054305e-15 1.02639996666659e-15 1 1.8488455076322 9.50051539882776 1.4436195315584e-12 178.971583210522 27.4080108460402 6.52990048113538 1.53202880362107e-10 -338.70885805351 164.581269944614 -2.05800367300297 0.040073642670399 SH2B1 other 1.35599182599281e-08 1 1.75463258878721e-06 6.52990048113538 -2.05800367300297 0.00437309011609281 4.58848113392729 1.79749289957907 2.55271168804161 0.0109602310873433 -3.73507711568868 4.48908451405298 -0.832035374695243 0.405753393850991 ZC3H12D other 1 1 1 2.55271168804161 -0.832035374695243 1.56736404864477e-14 9.62037276899529 1.24846046022875 7.70578890999285 6.1884789573227e-14 -9.6286557879375 6.22140072689988 -1.54766686966577 0.122282982766185 VN1R1 other 1.58993409094526e-10 1 7.74488141508936e-10 7.70578890999285 -1.54766686966577 2.16397215078431e-07 156.385286801075 38.8437968092209 4.026004140871 6.48345632906096e-05 -65.4078418327504 74.0748222943376 -0.882996945613332 0.377630110984925 KDELC2 other 0.00152733154402357 1 0.545258677274026 4.026004140871 -0.882996945613332 9.23642032473883e-14 1134.8845245636 147.472264510557 7.69557942525768 7.59586090239423e-14 -1142.88761521838 1005.44193956338 -1.13670175297709 0.256208557713559 PLEC other 9.09417945173786e-10 1 9.48571109490991e-10 7.69557942525768 -1.13670175297709 0.126525751776748 8.54910303678265 10.8098484011108 0.790862435767755 0.429374713943836 48.9725072126537 24.0872135730214 2.0331329343758 0.0425322220298768 RNF212 other 1 1 1 0.790862435767755 2.0331329343758 1.66910911998874e-07 12.8584895086541 2.43422876075737 5.28236693113977 1.88512133714759e-07 -10.4443591089291 14.3522273469875 -0.727716949879654 0.467117580843048 PRSS36 other 0.00118857260434398 1 0.00189567801663562 5.28236693113977 -0.727716949879654 4.10947368211476e-43 52.8854456774864 3.55306533831389 14.8844562770082 2.56792975553495e-42 -23.82680147106 17.6367460387737 -1.35097491445858 0.177262009142474 ZNF543 other 6.09763704952188e-39 1 3.89657661104874e-38 14.8844562770082 -1.35097491445858 4.73142039149781e-07 5.40985332612406 1.12426935739343 4.81188363851397 1.95229794748365e-06 -8.50781519930488 5.90587840032796 -1.4405672827318 0.150297440348946 TMEM151B other 0.0032457543885675 1 0.0184570247955104 4.81188363851397 -1.4405672827318 1.65889493335823e-18 146.188961571864 24.6409019369053 5.93277640348515 5.29789006032294e-09 -353.063259627373 73.7548161419033 -4.78698582812658 2.1839042288702e-06 GALNT11 other 1.89561924034845e-14 0.027307538477793 5.73231704526942e-05 5.93277640348515 -4.78698582812658 0.0336773128961478 21.6873124534019 9.12334191196643 2.37712371877198 0.0178083254569504 -1.68052930722301 19.620602799603 -0.0856512577308285 0.931776554649241 SLITRK1 other 1 1 1 2.37712371877198 -0.0856512577308285 1.72832121582626e-37 474.931741420336 126.842110368515 3.74427498912241 0.000201071429093072 -2349.47136012317 229.604409121661 -10.2326926957149 1.61758671136697e-22 WDR6 other 2.50209062415167e-33 2.50871523065903e-18 1 3.74427498912241 -10.2326926957149 7.76847632253531e-18 147.245790894313 16.3542187829096 9.00353559218534 3.68017407587878e-18 17.7058920023265 47.3122425089391 0.374234892776032 0.708375657817466 GEN1 other 8.73565162469095e-14 1 4.95682646280113e-14 9.00353559218534 0.374234892776032 0.0461835391327617 -1.10121774389581 7.60457016688153 -0.144809991850913 0.884914923901737 -33.9543484567268 14.9844347988625 -2.26597458712986 0.0238479460915993 TMPRSS9 other 1 1 1 -0.144809991850913 -2.26597458712986 9.13737964686016e-23 37.0847007131594 3.57610765648584 10.3701298382056 5.67054328701926e-23 4.95990792049161 21.7136206116463 0.228423808686761 0.819409246905305 AQP11 other 1.1413500916893e-18 1 8.00567301261379e-19 10.3701298382056 0.228423808686761 9.6790712501697e-64 180.853735465706 10.6689687397929 16.9513792641609 4.44394734722271e-52 -33.5792722897002 29.6715157026213 -1.13170060559912 0.258258028611563 TMEM11 other 1.49280315891367e-59 1 6.82456994112991e-48 16.9513792641609 -1.13170060559912 1.01367291123787e-12 28.8049529746158 5.17014362683958 5.57140285718209 3.98545418321757e-08 -41.7718028879867 13.9305473765987 -2.99857584621243 0.002836942251467 ZNF354B other 9.57616799246412e-09 1 0.00041580243493509 5.57140285718209 -2.99857584621243 0.108192416189376 78.0473478007804 37.8719376798682 2.06082267193496 0.0397947592224989 46.2888163701628 79.4691923263563 0.582474982003949 0.560488124140502 SHISA3 other 1 1 1 2.06082267193496 0.582474982003949 0.838342539661362 59.6016977431214 100.453535171721 0.593326035178698 0.553209120663553 26.9223309769794 436.193094740809 0.0617211306221549 0.950807539998342 CALML3 other 1 1 1 0.593326035178698 0.0617211306221549 0.131856110314909 410.539263232131 206.659352570105 1.98655061155707 0.0474725707342907 -42.8756349684412 896.3433136722 -0.0478339429930987 0.961866108194343 CALML5 other 1 1 1 1.98655061155707 -0.0478339429930987 2.5877469803721e-09 59.132045183732 10.5528197559782 5.6034355320277 3.41806575117365e-08 -58.3435278646727 37.8834789010579 -1.5400784077157 0.124151866264065 ZFAND2A other 2.07304410597609e-05 1 0.000357598038887787 5.6034355320277 -1.5400784077157 0.00177132901273488 50.789233265197 14.4653168790085 3.51110409056439 0.000483428786392347 8.89894018949227 35.4625095295206 0.250939380984428 0.801956079147526 PLEKHM3 other 1 1 1 3.51110409056439 0.250939380984428 2.10172033200526e-13 11.639152070865 3.21190107302444 3.62375795712323 0.000317479812348967 -60.8716920276413 10.8910439596655 -5.58915125612174 3.60709668193331e-08 ZNF223 other 2.04224164660951e-09 0.000484360942450005 1 3.62375795712323 -5.58915125612174 1.40053792885332e-21 94.4151447517321 10.5612861220918 8.93973931396829 6.03901449234536e-18 -90.7076852412735 37.1116002512523 -2.44418684797114 0.0148338011272882 FAM220A other 1.71075708009433e-17 1 8.11522767481369e-14 8.93973931396829 -2.44418684797114 3.33036808206237e-05 84.9388476566197 29.1266497167846 2.9161901036518 0.00369033199889683 -236.714451945057 89.1963360193728 -2.65385847120049 0.00819179434042501 DNAJC22 other 0.19226214937746 1 1 2.9161901036518 -2.65385847120049 0.342187193789128 1.82668476296357 11.1088534573937 0.164435040030867 0.869449424719678 33.347342239015 24.0817994637621 1.38475292468055 0.166692574663299 NEUROG2 other 1 1 1 0.164435040030867 1.38475292468055 0.259736583926789 19.9985133963228 14.3194219448797 1.39660060813235 0.163106386186313 45.0126461392949 40.645342706995 1.10744904929903 0.268591967563048 CEP295NL other 1 1 1 1.39660060813235 1.10744904929903 9.94150580580164e-39 92.9641496753926 6.97450717333909 13.3291352872586 3.90062315139456e-35 2.85832581086959 23.4139515783802 0.122077890239975 0.902883868087952 BEND3 other 1.44738383026666e-34 1 5.83026142438945e-31 13.3291352872586 0.122077890239975 6.00301063044914e-27 124.01049895899 20.4591360644343 6.06137515134703 2.54675251602757e-09 -435.182047095623 64.0023188511935 -6.79947312701949 2.80915046512701e-11 NT5DC1 other 7.96059239703861e-23 4.05191863089919e-07 2.78767530404377e-05 6.06137515134703 -6.79947312701949 0.0029142369830242 72.9498159992199 25.1705722102988 2.8982184191018 0.00390478197932926 -43.4232196884625 62.0117037028444 -0.700242326779851 0.484076442113469 GLDC other 1 1 1 2.8982184191018 -0.700242326779851 1.12069232245317e-14 131.273816706949 20.1907018992183 6.50169654141798 1.80482716361383e-10 -185.755710352784 58.9953889835732 -3.14864794610483 0.00173060525154177 COX14 other 1.14232168427652e-10 1 2.06284760217853e-06 6.50169654141798 -3.14864794610483 8.54099310408837e-36 77.0344813806348 5.67880975093783 13.5652513042743 3.54787290232788e-36 -38.1072628155489 53.2376164877936 -0.71579580998496 0.474433867702357 MCMDC2 other 1.22554710050564e-31 1 5.31719711871879e-32 13.5652513042743 -0.71579580998496 0.118162398982274 2.61718071484244 3.50999270616203 0.745637080740311 0.456209320116108 -27.3825378709549 15.2203920958308 -1.79906915002903 0.0725628698142138 TUBAL3 other 1 1 1 0.745637080740311 -1.79906915002903 7.6495194703736e-26 73.258150236255 60.0316278780157 1.22032589862656 0.222892348546458 -1017.79189251429 108.642351549772 -9.36827929435986 2.20635382437885e-19 P4HTM other 1.00055714672487e-21 3.38962138039323e-15 1 1.22032589862656 -9.36827929435986 0.7950076020509 -6.30090747132836 10.2737393996861 -0.61330224820778 0.539933310722035 -16.7561425310575 44.5500475482726 -0.376119520700875 0.706974948047332 UCN3 other 1 1 1 -0.61330224820778 -0.376119520700875 1.60973432528474e-11 51.3456697863336 25.8618616996674 1.98538180980969 0.0476319491222769 -457.782014930482 73.546395337425 -6.22439771290238 1.00303436933e-09 DTX3 other 1.44296584918524e-07 1.40495024112053e-05 1 1.98538180980969 -6.22439771290238 6.03194520013389e-15 21.3082817875255 4.66847869762787 4.56428810489219 6.22806195566171e-06 -47.3451899869531 10.7540554864506 -4.40254284038284 1.2932259199827e-05 KLHL11 other 6.21531633421796e-11 0.155122449101924 0.0569680827084377 4.56428810489219 -4.40254284038284 0.000284288759335909 71.1604851839 38.8291898684365 1.83265438771734 0.0673983788260474 -302.001744363385 107.893758154271 -2.79906594718455 0.00530629095948659 CTXN1 other 1 1 1 1.83265438771734 -2.79906594718455 1.93502759865091e-22 67.8030701869837 15.8652302020838 4.27368965488306 2.28355620440117e-05 -183.029416897484 28.7071581214226 -6.3757414134595 3.99339335795049e-10 SLC25A20 other 2.4034977802843e-18 5.64386283279143e-06 0.19997101681941 4.27368965488306 -6.3757414134595 1.90544168662534e-06 109.036063655829 21.683420792385 5.02854529734171 6.84288468666122e-07 -136.389610077896 185.010459470466 -0.737199456010588 0.461338091732306 CA8 other 0.0124144841334479 1 0.00665333678084071 5.02854529734171 -0.737199456010588 0.944530508621067 0.0882605776912381 5.04928490474905 0.0174798173119971 0.986060290214084 -3.99096523557421 12.5189476492538 -0.318793987113772 0.750006007312636 CD28 other 1 1 1 0.0174798173119971 -0.318793987113772 1.42587788913099e-16 23.0373017442556 38.7296235611577 0.594823797031684 0.552209036466537 -598.734073776327 76.4616862390514 -7.83051098172793 2.56547116526394e-14 EPM2AIP1 other 1.54622198297365e-12 3.82768297857379e-10 1 0.594823797031684 -7.83051098172793 5.81761659047096e-08 -351.25765133084 100.458408472786 -3.49654804083417 0.000509818978758805 -1298.47017581766 236.029044813861 -5.50131521669998 5.81033710107576e-08 ERBB4 other 0.000428932871215424 0.000775040865912496 1 -3.49654804083417 -5.50131521669998 0.412469791800758 -31.9001637417668 38.959409940418 -0.818805104865625 0.413254844775755 -110.501227553818 82.980532794229 -1.33165242295844 0.183530082143261 MAF other 1 1 1 -0.818805104865625 -1.33165242295844 2.88030312022539e-16 315.208677714459 50.8835001967788 6.19471295204674 1.15559312964957e-09 -187.290425399804 83.6396547904094 -2.23925392649134 0.0255442493661383 CTNNBIP1 other 3.09661388455432e-12 1 1.28351728910178e-05 6.19471295204674 -2.23925392649134 1.85756310937937e-14 140.543294847684 20.9458398430972 6.70984290438948 5.10267404225403e-11 -331.698192736601 98.0135570946256 -3.38420727263646 0.000767721689078687 ERN1 other 1.8787393288263e-10 1 5.9236942956527e-07 6.70984290438948 -3.38420727263646 0.0841952350889371 3.38737612403715 3.88472734791807 0.871972681905858 0.38360725076901 -12.1812749564609 7.56295562417473 -1.61065006351801 0.10783499719215 GPR35 other 1 1 1 0.871972681905858 -1.61065006351801 0.0827925160545549 -12.4915916502353 8.08875498576501 -1.54431574107741 0.123096583987673 -40.2786647293798 20.1563924167547 -1.99830723160057 0.0461833768329334 CSRNP3 other 1 1 1 -1.54431574107741 -1.99830723160057 0.0106293896385272 6.36102534072845 6.72483674032738 0.945900337265107 0.344633731929332 -77.2951816298174 29.1707325314814 -2.64975113485407 0.00829748957660306 ZNF713 other 1 1 1 0.945900337265107 -2.64975113485407 4.75896832883734e-10 321.136016684513 52.0240188149823 6.17284139133114 1.3862541735779e-09 -636.319340394543 358.597559512165 -1.77446645554473 0.0765932287741032 PARP10 other 3.96945548308323e-06 1 1.53416749389867e-05 6.17284139133114 -1.77446645554473 1.16551625668051e-32 395.624754708135 34.9787500563188 11.3104314496986 1.18022885862198e-26 -103.533553323115 83.4762459267823 -1.24027562779865 0.215436049284573 SUZ12 og 1.63370413698907e-28 1 1.70672895245325e-22 11.3104314496986 -1.24027562779865 9.15979346852354e-10 26.5894924626872 5.53857519456429 4.80078206553608 2.07977338489989e-06 -76.5807255138076 19.1334035480404 -4.00246225516164 7.19891230738168e-05 NSUN3 other 7.5110306441893e-06 0.820244068303068 0.0196351405268399 4.80078206553608 -4.00246225516164 0.116771889248671 -195.344994540801 114.23383553781 -1.71004495840589 0.0878506581415385 -398.971199489264 219.208670470621 -1.8200520929793 0.0693225256731208 KCTD12 other 1 1 1 -1.71004495840589 -1.8200520929793 2.07229916662262e-06 28.7564814372759 10.4875623384783 2.74196047748579 0.00632280955724322 -148.29798229429 36.1450645723228 -4.10285564707072 4.75269474785131e-05 DHFR2 other 0.0134575107880473 0.549316458956655 1 2.74196047748579 -4.10285564707072 4.83807941870255e-10 176.567091851577 29.2187027320338 6.0429476787824 2.83146744232344e-09 250.724051970923 56.1326486736853 4.46663497795111 9.69307456281556e-06 RPP25 other 4.03302300343044e-06 0.117131113017063 3.09394447422682e-05 6.0429476787824 4.46663497795111 1.92179623892045e-41 1844.91991213477 125.377306226662 14.714942980187 5.38856971900319e-41 -1186.72842064111 864.216126612318 -1.37318476720982 0.170309151972953 GRINA other 2.83176675804928e-37 1 8.15937226851463e-37 14.714942980187 -1.37318476720982 0.00305238875057583 -81.7949663694728 31.260730255555 -2.61654048708404 0.00913272965269971 -350.975328845137 125.304080980082 -2.80098881137738 0.00527828101627584 THBD other 1 1 1 -2.61654048708404 -2.80098881137738 2.13985345097056e-10 418.80724848779 61.4630359004523 6.81396944280633 2.56045026702463e-11 233.973454106377 118.246844474176 1.97868666302952 0.0483627423582731 COX5A other 1.81994536005046e-06 1 3.00238398311308e-07 6.81396944280633 1.97868666302952 0.11204195090082 3.71424549470486 2.68903653820473 1.3812551231396 0.167807779347892 15.8231680432261 9.26768262956022 1.70734893238105 0.0883682369682325 STX19 other 1 1 1 1.3812551231396 1.70734893238105 6.29155334047017e-06 3.99659327073991 2.66453174788108 1.49992330694431 0.134211202143996 25.5295300744389 5.16833939934134 4.93960015042595 1.04174891019922e-06 ERFE other 0.0388755080907652 0.0132166684236975 1 1.49992330694431 4.93960015042595 1.61579533029046e-21 130.195488903329 26.6613902771969 4.88329706552038 1.37974464051646e-06 -371.598797433207 51.2692842934334 -7.24798098031577 1.4874443374963e-12 FAM219B other 1.9709471438883e-17 2.18118837650458e-08 0.0131641436151675 4.88329706552038 -7.24798098031577 1.87287193627724e-09 88.7822287797636 16.3061531427087 5.44470716071144 7.9309919968054e-08 -608.43803342246 182.277887783147 -3.33796951908016 0.000902869835668685 ZHX2 other 1.51365509889927e-05 1 0.000815068047511691 5.44470716071144 -3.33796951908016 0.0303656456514904 57.5698792201472 29.3235481997943 1.96326443266341 0.0501399084402353 165.708497863363 63.2496427722471 2.61991199634211 0.00904834992312193 CPNE7 other 1 1 1 1.96326443266341 2.61991199634211 2.2237354737591e-08 -8.28493104319434 14.8035508114518 -0.559658364990732 0.575941159352467 190.210848623826 34.9993268670006 5.43470019713916 8.27174358565155e-08 C5orf46 other 0.000168581386265677 0.00109807396099524 1 -0.559658364990732 5.43470019713916 0.205002418003804 -2.53326620516117 2.0307670994608 -1.24744300113676 0.212777828643437 -10.3889027761323 6.85639303684229 -1.5152140083435 0.130305497177625 CD300LB other 1 1 1 -1.24744300113676 -1.5152140083435 0.014137266725446 4.17862774271395 1.42647171064831 2.92934497860797 0.00353897441322216 -2.46175071701892 17.967032886111 -0.13701487232886 0.891069639625276 RIIAD1 other 1 1 1 2.92934497860797 -0.13701487232886 2.94871841031648e-37 260.738611100492 35.2184288973008 7.40347083229698 5.18544440212009e-13 -634.276619534402 67.7242868706704 -9.36557103577402 2.09320952291617e-19 MPI other 4.26207759027144e-33 3.21663507386527e-15 6.34439122599393e-09 7.40347083229698 -9.36557103577402 0.000292031586419749 24.8698083867835 8.58369318314861 2.89733193581611 0.00391453669730714 -20.697428795494 19.0276441486043 -1.08775572182498 0.277182887872576 ADORA2A-AS1 other 1 1 1 2.89733193581611 -1.08775572182498 0.0770714786549227 0.898019489277922 2.83923317616226 0.3162894463257 0.751914291563129 -22.7501214944612 10.7908423021867 -2.10828041568645 0.0355016908189317 TRIM73 other 1 1 1 0.3162894463257 -2.10828041568645 9.25390371133131e-15 128.203311051774 15.8752008420921 8.07569695193093 5.07116502081557e-15 -95.9735592446155 109.333892251831 -0.877802456932176 0.380473369729367 OPLAH other 9.46396732557853e-11 1 6.48602006162311e-11 8.07569695193093 -0.877802456932176 0.0208890253164831 15.0253199915129 7.20631613892085 2.08502093189641 0.0375356505517969 -12.0537055136503 14.6688713552767 -0.821720037057545 0.411598231975588 TMEM52 other 1 1 1 2.08502093189641 -0.821720037057545 0.0832929813100719 47.6373424009664 23.0892352196956 2.06318407464318 0.0395673218243527 -10.926228388211 74.9899319900655 -0.145702604313049 0.884209938702803 TMEM139 other 1 1 1 2.06318407464318 -0.145702604313049 9.28337452781067e-20 14.0551990640622 2.69259729338075 5.2199410207439 2.57058949169077e-07 -37.8887728802375 6.67123633075863 -5.6794229737517 2.22619332660539e-08 EFCAB13 other 1.09469552431943e-15 0.000300847766157452 0.00256544831270739 5.2199410207439 -5.6794229737517 0.587495472288764 -5.85125936712723 7.23502819164011 -0.808740368681384 0.41902944779332 -49.6638592243868 67.9332470526072 -0.731068532406928 0.465062205310868 MSC other 1 1 1 -0.808740368681384 -0.731068532406928 1.76512561538845e-19 471.23814138447 57.519943237648 8.19260442308703 1.85560275722558e-15 -396.899182770627 183.140312260315 -2.16718633856251 0.0306562462618556 APOLD1 other 2.06784465842756e-15 1 2.3929853157181e-11 8.19260442308703 -2.16718633856251 0.350656198810435 43.5320062971073 31.9769456183606 1.36135598492284 0.173966884520359 63.1718847586118 72.4501301636474 0.871936111307485 0.383629308748272 RFLNA other 1 1 1 1.36135598492284 0.871936111307485 1.08930575664741e-07 142.495800436268 30.1349210550913 4.72859378578638 2.89420325516558e-06 -286.925421900885 133.378193994107 -2.15121687667748 0.0319053129894333 DPY19L3 other 0.000786260895148101 1 0.027075271452074 4.72859378578638 -2.15121687667748 5.69724598120897e-14 312.127620887098 72.064016575526 4.33125484422556 1.76737886409431e-05 -841.417104855531 176.1940168248 -4.77551462880945 2.31103832238649e-06 TAF7 other 5.65679553474239e-10 0.0288648686466073 0.155953510967682 4.33125484422556 -4.77551462880945 2.25663627322093e-20 3.955026453729 1.87858782731062 2.10531889764824 0.035725648732652 -27.0653479346319 3.60223501843207 -7.51348754207951 2.41015996590726e-13 ZNF852 other 2.69126441944328e-16 3.56366252559047e-09 1 2.10531889764824 -7.51348754207951 2.61126669680833e-39 101.482391390519 17.809365805044 5.69825969669154 1.98323615913864e-08 -300.114009505382 31.6752421740048 -9.47471870480847 8.10243664987332e-20 PFAS other 3.81218825067048e-35 1.2472890978815e-15 0.000209806553275277 5.69825969669154 -9.47471870480847 9.12918511977697e-08 -6.72486100352145 28.7946962897618 -0.233545127055656 0.815426637872404 -354.49948821829 64.0441113301585 -5.53523939758933 4.85519995724332e-08 HYI other 0.000661592045630237 0.000649285890282149 1 -0.233545127055656 -5.53523939758933 3.19459903147266e-25 303.760073238344 35.8578187688443 8.47123678092409 2.47367377877257e-16 -572.917750944776 102.214870815733 -5.60503326348277 3.37332526757793e-08 C17orf62 other 4.13956142498227e-21 0.000453206249699095 3.2380389764133e-12 8.47123678092409 -5.60503326348277 1.60767770621442e-26 634.76274727148 60.1645001123991 10.5504532753637 9.37556839153477e-24 -864.422264026264 299.76334703866 -2.88368231995615 0.00408998318794794 ZNF552 other 2.12052689449682e-22 1 1.33226826843709e-19 10.5504532753637 -2.88368231995615 5.80191451785179e-40 810.593895450391 76.5460560545929 10.5896232573011 8.03769223933187e-24 -788.501594996544 171.316405947559 -4.60260411508931 5.27279712565124e-06 GAK essential 8.49806419429752e-36 0.0647183119202433 1.1428794595106e-19 10.5896232573011 -4.60260411508931 8.12060386947433e-31 9.54850932348967 24.7959433379976 0.385083527306558 0.700326045036415 -688.923975360085 59.8335821190481 -11.5140018524942 1.32468404245545e-27 ZBTB7A other 1.11901921321356e-26 2.06928894271966e-23 1 0.385083527306558 -11.5140018524942 0.071235945646879 -8.38700832915304 20.3948711348555 -0.411231248959419 0.68106552601379 -92.7256249411151 40.966959054444 -2.26342464955442 0.0240041525723445 ERICH3 other 1 1 1 -0.411231248959419 -2.26342464955442 3.43312377852517e-12 131.999783571119 22.0275296124334 5.99249148195953 3.78713427595901e-09 -113.477768049823 48.6282853406575 -2.33357535135926 0.0199853938054742 RMI1 other 3.17804268178075e-08 1 4.11888723853302e-05 5.99249148195953 -2.33357535135926 1.96665202547062e-60 34.582597977741 29.0611765303537 1.18999304593261 0.234567241113856 -850.960667795786 51.7992250063171 -16.4280579041869 1.46818804352872e-49 CTC1 other 3.02392415436363e-56 2.30226567105738e-45 1 1.18999304593261 -16.4280579041869 1.69745216291189e-19 62.8648294588808 17.0346924484463 3.69040002624847 0.000246571201299233 -267.712454408133 37.6512714982635 -7.11031643169024 3.68074264044178e-12 FBXO34 other 1.98941393493273e-15 5.37351618078095e-08 1 3.69040002624847 -7.11031643169024 3.16752680049835e-27 1.19290940889466 5.58954497183652 0.213417982126497 0.831080767209074 -103.699638818712 9.96291727475924 -10.4085616651091 2.90235263707467e-23 LINC00324 other 4.2147111607431e-23 4.50648293958583e-19 1 0.213417982126497 -10.4085616651091 6.49155920169756e-09 688.840468670954 155.148760807731 4.43987090251144 1.08974541407913e-05 -1193.57475081932 438.346006747161 -2.72290549576691 0.0066780134764892 SELENOW other 5.08418916676953e-05 1 0.0978809330925876 4.43987090251144 -2.72290549576691 3.22079642670117e-51 1391.29038251175 83.0050445770806 16.7615159970158 3.66904898784998e-51 208.071901347064 450.679468420728 0.461684891207025 0.644491528715867 EIF3K other 4.88337154216431e-47 1 5.63052257675458e-47 16.7615159970158 0.461684891207025 1.54271736599246e-44 287.045014682528 53.0778263570936 5.40800244439864 9.55878632247833e-08 -1034.16769129052 102.114600019425 -10.1275203652934 3.35508084833939e-22 MRFAP1L1 other 2.29972877748496e-40 5.20003980684121e-18 0.000977672665063083 5.40800244439864 -10.1275203652934 8.61663394679386e-07 90.029473606335 28.053153000921 3.20924616221854 0.00141001343378714 -171.368964528773 65.7873271910078 -2.6048932498993 0.00944403362179662 SNX18 other 0.00579123967564016 1 1 3.20924616221854 -2.6048932498993 3.66126245343053e-20 214.239380826263 23.369818242889 9.16735331869568 9.85789417266855e-19 304.008508713202 41.6548336319337 7.29827686744477 1.03649058353023e-12 AURKB essential 4.34774916344875e-16 1.5226046672059e-08 1.33682902875558e-14 9.16735331869568 7.29827686744477 7.1448313216545e-08 11.8367255837551 5.58516849307555 2.11931396491086 0.0345163027716112 71.2541051587854 12.2338384773086 5.82434575141303 9.81657143199242e-09 C14orf39 other 0.000522430066239377 0.000134271064046792 1 2.11931396491086 5.82434575141303 5.50187941162583e-41 1381.37752893737 205.582686522866 6.7193281316699 4.61538651535085e-11 -3266.63815716648 395.513442166338 -8.25923422292348 1.12035896160057e-15 MRFAP1 other 8.09051367479579e-37 1.6910698166399e-11 5.36354066948922e-07 6.7193281316699 -8.25923422292348 1.18185308764745e-10 38.9381739629144 12.0266068098047 3.23766915961451 0.00128746763466862 -109.966688714826 25.0806167999333 -4.38452888108871 1.42580172850137e-05 C3orf38 other 1.01497543167163e-06 0.170511628711479 1 3.23766915961451 -4.38452888108871 0.000294921682427948 -328.384508528879 155.906238047078 -2.10629486441536 0.0356353642747877 -1016.71003160762 250.2824301614 -4.06225091770114 5.57410862879384e-05 KLHDC7A other 1 0.640855269052427 1 -2.10629486441536 -4.06225091770114 1.62364860055167e-51 47.9163398649266 8.9912439257619 5.32922254813216 1.44518434181122e-07 -196.074976080405 16.0321162102634 -12.2301369020069 1.43719549480775e-30 TMEM107 other 2.46226310273661e-47 2.24921094937412e-26 0.00146151492487369 5.32922254813216 -12.2301369020069 5.89083610760875e-70 252.943563028325 12.1809738877372 20.7654630376449 2.13017608391746e-70 -25.9219161568515 111.49445217959 -0.232495121058559 0.816243908987464 RRS1 essential 9.11724704374607e-66 1 3.30667233506507e-66 20.7654630376449 -0.232495121058559 0.0762535415281505 2.04768951556605 4.42686069909365 0.462560187625802 0.643875401456625 -14.7994538431927 9.68625885985232 -1.52788130663466 0.127157128762235 EXOC3L1 other 1 1 1 0.462560187625802 -1.52788130663466 1.47076882262702e-12 1537.69798842987 229.474928337614 6.70094114232616 5.15209890143584e-11 204.723756757457 368.363828452968 0.555765091315408 0.578598276061054 RCC2 other 1.38105192444677e-08 1 5.97952598500644e-07 6.70094114232616 0.555765091315408 0.00061173897029731 -0.330965994357152 4.43142779763419 -0.0746860852689161 0.940491934319982 -42.4988426062767 11.612930440208 -3.65961398159511 0.000277207916929487 IGSF22 other 1 1 1 -0.0746860852689161 -3.65961398159511 0.0170731723759617 12.5577379052628 14.6939315163067 0.854620690951685 0.393148764226722 87.5239417527836 30.9266528839247 2.83004895748927 0.00483131077428166 ZFP42 other 1 1 1 0.854620690951685 2.83004895748927 1.81615432142499e-05 7.77637997188533 1.96673211975781 3.95395991846766 8.73657875691518e-05 -1.64182383433902 4.51866498051638 -0.363342677852473 0.71649461542812 CCDC89 other 0.107879566692644 1 0.725660231549375 3.95395991846766 -0.363342677852473 6.38751172119551e-08 82.4475227155421 14.1059935727215 5.84485752744003 8.91055098097941e-09 -17.2880925860523 147.017224361176 -0.117592293428018 0.906435685016619 DPM3 other 0.000468971110570174 1 9.55300170670803e-05 5.84485752744003 -0.117592293428018 2.14906944230254e-37 700.036534670502 49.5925826997989 14.115750714337 2.61517296562856e-38 186.50641492792 341.548440698361 0.54606138604109 0.5852677846451 CYC1 essential 3.10905876217908e-33 1 3.93845048623662e-34 14.115750714337 0.54606138604109 0.778034679641533 -2.46899027226362 3.51070133387968 -0.703275510347995 0.482219451601729 -2.60458857427544 7.314482695034 -0.356086504387216 0.721929671591711 HTR1F other 1 1 1 -0.703275510347995 -0.356086504387216 1.50172241973628e-06 -15.0004465171745 23.462676816936 -0.639332273730455 0.522881982129905 -311.083977484096 60.0186856739581 -5.18311879027159 3.1039921932439e-07 TMTC2 other 0.00986631629766737 0.00402370508010207 1 -0.639332273730455 -5.18311879027159 1.20983434849351e-30 355.810757621603 32.3122103825172 11.0116501907315 1.42997169119764e-25 -247.874888402725 101.748169435495 -2.43616066783264 0.0151675171068193 FARSA essential 1.66509501383161e-26 1 2.05458332591277e-21 11.0116501907315 -2.43616066783264 5.559053581331e-21 247.256446957728 36.6456526477884 6.74722454349984 3.8538706078497e-11 -430.524141285365 92.8041340461466 -4.63906210332492 4.38589837168219e-06 SPTY2D1 other 6.71478082088972e-17 0.0540474256342396 4.49053003226647e-07 6.74722454349984 -4.63906210332492 1.36638442107265e-64 651.230182066003 34.0147257474595 19.1455367566691 9.04701873050579e-63 -94.3650322172878 185.814252730823 -0.507846038882648 0.611768302827544 SAMD4B other 2.10887771548353e-60 1 1.39984520817116e-58 19.1455367566691 -0.507846038882648 0.507235513322404 -12.3361131723446 11.5025922525667 -1.07246374569105 0.283985572022262 2.6481854983562 35.5437143819692 0.0745050297753794 0.940635827110387 GIMAP7 other 1 1 1 -1.07246374569105 0.0745050297753794 5.40426981382319e-05 13.2990699300926 4.85208407029889 2.74089849586497 0.00632784456193163 -17.0187085335967 8.6516589160835 -1.96710349988009 0.0496771784022187 ALOXE3 other 0.304004006201599 1 1 2.74089849586497 -1.96710349988009 1.25322457650071e-21 191.16586252674 21.8177463448483 8.76194358047799 2.5063940745968e-17 -110.36776562439 42.0325561675259 -2.62576858719955 0.0088914655042391 EDC3 other 1.53219236722977e-17 1 3.33701307091817e-13 8.76194358047799 -2.62576858719955 1.14347793026559e-15 61.6397611472092 13.5691494121151 4.54264001929071 6.85303570311808e-06 -109.320708762291 25.9662114572687 -4.21011393757594 2.9881316546023e-05 TCAIM other 1.20671225980927e-11 0.349671166221561 0.0625133916838431 4.54264001929071 -4.21011393757594 7.41322940897595e-08 -95.1739852680526 66.6515566949708 -1.42793341952408 0.153882737793934 -588.991354522239 106.160925212938 -5.5480992968066 4.50768856623802e-08 FUCA1 other 0.000541239879149334 0.000603579499019271 1 -1.42793341952408 -5.5480992968066 4.21624828186124e-18 3.69563462220671 0.415444986764216 8.89560529058486 8.54972486680033e-18 -2.24856861453656 2.48195962229518 -0.905965026319491 0.365354711323924 GGN other 4.76984168126962e-14 1 1.14643260738926e-13 8.89560529058486 -0.905965026319491 0.249610609266714 2.42591017965986 1.50159910939854 1.61555115774645 0.106769040887303 3.13275550664458 2.75510809065046 1.13707172407343 0.256007070082011 HNRNPCL1 other 1 1 1 1.61555115774645 1.13707172407343 2.25437862207295e-07 26.7325497060583 25.8812871438574 1.03289104430816 0.302116396650794 -285.021988850899 58.2882822087698 -4.8898677066866 1.33234432224586e-06 TMEM125 other 0.00158866061497481 0.0168275087899652 1 1.03289104430816 -4.8898677066866 4.90969838160985e-16 846.338408268483 137.133373197968 6.17164435273312 1.3231023150265e-09 -1254.75080148265 310.682368978292 -4.03869329826798 6.14930452908549e-05 ZNF664 other 5.23766623350139e-12 0.704402833806743 1.46599736504936e-05 6.17164435273312 -4.03869329826798 0.00057453458153317 2432.45745917711 632.840854848546 3.84371116456957 0.000135666154792575 1137.74821654526 1992.75746730321 0.570941640020532 0.568277603548763 CALR other 1 1 1 3.84371116456957 0.570941640020532 0.00491436461967943 -170.029808622878 136.585923456895 -1.2448560167808 0.213737961252191 -1228.04392257522 375.306707544635 -3.2721075799829 0.00113741317883632 LDLRAD3 other 1 1 1 -1.2448560167808 -3.2721075799829 0.0564259560926313 4.89667583332866 2.04339254634849 2.39634613627173 0.0169116934807065 8.43138211637196 21.0880649523187 0.399817723220968 0.689454952382847 CDH4 other 1 1 1 2.39634613627173 0.399817723220968 0.273039026256441 10.3007582167476 14.5847878664001 0.706267263610884 0.480327681832362 -53.1946588133954 46.1510230412708 -1.15262144385891 0.249577671857214 SMCO3 other 1 1 1 0.706267263610884 -1.15262144385891 8.85503361221637e-33 740.631302306403 63.0113238127958 11.7539397284652 1.49995868793994e-28 -373.059615717808 198.416845389447 -1.88018116599716 0.0606234347156928 RAD23A other 1.24315816881906e-28 1 2.19083965960508e-24 11.7539397284652 -1.88018116599716 1.92971223907344e-14 539.583665181057 74.6724978545944 7.22600262055996 1.71270643269565e-12 -358.497101650269 235.136806610784 -1.52463200813848 0.12793850732956 GADD45GIP1 other 1.94997421758371e-10 1 2.07305986613482e-08 7.22600262055996 -1.52463200813848 4.46695804953355e-12 630.532282595685 96.1776804544577 6.55591068131713 1.29427831199208e-10 -278.65861047046 213.952855401795 -1.30242996732692 0.193324644012307 PTPN11 essential 4.1140683636204e-08 1 1.4863492134917e-06 6.55591068131713 -1.30242996732692 5.90826408457423e-12 24.4840394167028 10.1338363810726 2.41606815977733 0.0160156275501126 -100.503215163711 20.7205389860053 -4.85041509931721 1.60853549951416e-06 NSUN7 other 5.4161056863292e-08 0.0202321595128892 1 2.41606815977733 -4.85041509931721 0.000170828570299076 7.66564674015416 2.05485054889812 3.7305130264898 0.000211350031404636 14.66365515884 3.92967924815081 3.73151451629044 0.000210532634843914 RAB39A other 0.899754079765232 1 1 3.7305130264898 3.73151451629044 3.119358788912e-18 163.478820321723 25.7736769880398 6.3428598254562 4.78563610897978e-10 -235.376310995983 49.653777641395 -4.74035052671916 2.73513174232183e-06 CLK3 other 3.54078416129402e-14 0.0340578604553914 5.3948475856529e-06 6.3428598254562 -4.74035052671916 0.170648212197821 228.478909522508 153.454791280132 1.4889004612793 0.137090933262054 843.771877779108 536.402188585525 1.57302094535465 0.116293224652481 HLA-DQB1 other 1 1 1 1.4889004612793 1.57302094535465 0.382023574508789 -10.41654164986 43.9734685615665 -0.23688242002734 0.812837842477208 -201.565991720651 145.204333178177 -1.38815410882617 0.165662535730526 GATA2 other 1 1 1 -0.23688242002734 -1.38815410882617 1.55928249222845e-05 19.6496831508393 5.55320323786647 3.53844120396153 0.000437312233648543 -21.764703750988 10.7422596035664 -2.02608245883037 0.043249272974712 ARID3B other 0.0932139073854168 1 1 3.53844120396153 -2.02608245883037 8.64558936841928e-17 220.563696632107 36.6618009642822 6.01617189638316 3.37496713758865e-09 -295.965168967303 79.8357399083199 -3.70717637623422 0.000232128912760929 PACS2 other 9.43752535456649e-13 1 3.67736419311659e-05 6.01617189638316 -3.70717637623422 8.79515783452994e-31 137.913279716758 31.1043765938531 4.43388663651959 1.12167932045868e-05 -648.100203892991 69.8370244419546 -9.28018066450788 4.07257533405444e-19 ELMOD2 other 1.21144504012815e-26 6.25018136517336e-15 0.100678260228549 4.43388663651959 -9.28018066450788 0.000506318240382637 108.082645839281 90.8193213384565 1.1900842711265 0.234538155851377 -394.649470318837 184.052113718406 -2.14422677548076 0.0324621261475962 EGR3 other 1 1 1 1.1900842711265 -2.14422677548076 1.64426162871709e-06 2.97980993663762 0.596293918600039 4.9972167142565 7.85706683865061e-07 -4.78161786636632 3.74000055982149 -1.27850725952687 0.201616809471223 CATSPERE other 0.0107666251448395 1 0.00761114064660085 4.9972167142565 -1.27850725952687 3.94881658651001e-05 371.216756393693 129.974854426536 2.85606595238397 0.00445751979473536 -461.652779555292 247.597544523214 -1.86452890897716 0.0628000039893853 VWA1 other 0.226346166738754 1 1 2.85606595238397 -1.86452890897716 0.000349397921541037 24.2489488257391 11.1299302286913 2.17871525943882 0.0297943231516051 -120.573474513809 42.4799234916265 -2.83836373993415 0.00470908401790978 LINC00174 other 1 1 1 2.17871525943882 -2.83836373993415 2.38287247046001e-31 182.759574556229 20.5474332875019 8.89452088730684 9.06976414595542e-18 -163.728499540143 37.682523909993 -4.3449451509994 1.66796146290237e-05 GEMIN4 essential 3.30337610579872e-27 0.198804326763333 1.21525769791657e-13 8.89452088730684 -4.3449451509994 0.908528271715797 7.92788629452697 20.7860550974117 0.381404083524927 0.703057444788758 18.664324438426 56.7034754918414 0.329156621821381 0.742168326827934 FJX1 other 1 1 1 0.381404083524927 0.329156621821381 1.3039041945744e-11 33.0105559389208 20.0595660178957 1.64562662569426 0.100439162786099 -280.444756173642 45.2663190166737 -6.1954398384004 1.17517103282912e-09 KLHL28 other 1.17494806973099e-07 1.64347668941153e-05 1 1.64562662569426 -6.1954398384004 1.95889695403181e-12 27.4237297041558 3.94790497429943 6.94640065621697 1.10446565791307e-11 47.0559631508197 8.4978024263978 5.53742730057406 4.84132325349509e-08 MKRN3 other 1.83021155442925e-08 0.000647478571922434 1.30912314432436e-07 6.94640065621697 5.53742730057406 9.86082396986993e-06 376.070420477445 93.5416794570358 4.02035138411403 6.63001856149846e-05 -1522.13769463254 594.266043464775 -2.56137417133572 0.0106938889132161 ZBTB18 other 0.0600031138566585 1 0.557054159537101 4.02035138411403 -2.56137417133572 6.01851095533748e-26 11.935647149093 2.87027373244189 4.1583654597775 3.74353862550598e-05 -56.9033509169709 6.47704573079907 -8.78538662254447 2.21516445696274e-17 C14orf28 other 7.88545305368316e-22 3.37812579686818e-13 0.321757144862239 4.1583654597775 -8.78538662254447 1.09306417017365e-27 323.944114843887 28.2603481142472 11.4628494148157 3.65029222419259e-27 -306.979032887761 194.631481293132 -1.57723216639051 0.115375822475659 SHARPIN other 1.46208263402427e-23 1 5.29182863741199e-23 11.4628494148157 -1.57723216639051 0.0102498231150686 5.00962146395809 4.07730960514367 1.22865858840797 0.219735019414523 -35.8264939407723 13.950210192646 -2.56816875488073 0.010491502218276 LBX2 other 1 1 1 1.22865858840797 -2.56816875488073 5.98282319117673e-07 42.3776023268002 10.6799566373585 3.96795640335874 8.22983101529644e-05 -44.6257922799805 24.4582626646256 -1.82456918105322 0.0686194852122091 DNHD1 other 0.00407131118159576 1 0.685462625264041 3.96795640335874 -1.82456918105322 0.016206506660248 12.5944656895186 5.01279469301965 2.51246389704659 0.0122762827589036 1.06305145403145 7.89031780193363 0.13472859784823 0.892876111287443 HTR1D other 1 1 1 2.51246389704659 0.13472859784823 9.58684587036704e-38 191.561471089869 22.5945115482468 8.47823024103981 2.15996074642221e-16 -546.605225695848 69.6937470523352 -7.8429593588272 2.34024131436057e-14 GCC1 other 1.38932570353359e-33 3.49304418581459e-10 2.83041256211167e-12 8.47823024103981 -7.8429593588272 1.84898258225208e-06 39.1128905587593 10.0380388614967 3.89646733773728 0.000110231071219669 -21.1991914013048 18.4611129079012 -1.14831600386517 0.251361078992087 LSMEM2 other 0.0120609133840303 1 0.907311947209097 3.89646733773728 -1.14831600386517 4.68412285238278e-05 98.0687219731052 22.5007244956567 4.35846952359402 1.5678753237325e-05 19.9313870523076 117.000523556823 0.17035297318672 0.864796240637598 CIITA other 0.266151860472389 1 0.138929432435937 4.35846952359402 0.17035297318672 0.299327285259134 5.97774811906798 9.10914357263727 0.656236019489734 0.511956536766974 -13.4120732300287 19.617015215919 -0.683695918181528 0.494465432712081 ZFPM1 other 1 1 1 0.656236019489734 -0.683695918181528 0.902629635014682 -91.7196359633928 334.562107279953 -0.274148308991383 0.784074146487995 120.802537009075 596.7711711551 0.202426898027349 0.839658268528075 ALOX15B other 1 1 1 -0.274148308991383 0.202426898027349 6.5283267598719e-29 72.4856149278557 9.17157626867619 7.90328868282073 1.55438945563291e-14 -70.2691746693436 16.1026335348564 -4.36383120296665 1.53372088202818e-05 PLD6 other 8.84849409033037e-25 0.18309828099069 1.96972231817803e-10 7.90328868282073 -4.36383120296665 0.849331858010445 -0.417410096136341 1.18046459120443 -0.353598150462486 0.723777304847418 1.1097703151822 3.64085048024898 0.304810736173463 0.760627095841247 GRM8 other 1 1 1 -0.353598150462486 0.304810736173463 3.55827510976944e-09 413.324554649029 65.2926798852104 6.33033527457727 5.23869152669266e-10 382.589252316167 215.229840596412 1.7775846102752 0.0760487070497984 CDC42EP4 other 2.82989619479964e-05 1 5.89405183668191e-06 6.33033527457727 1.7775846102752 7.10314094404572e-26 108.038916129271 33.7813996214936 3.19817761667076 0.00146482561687336 -622.275582780399 70.5451905766238 -8.82094977267804 1.60489823251666e-17 ZBTB42 other 9.29801149575585e-22 2.44875372317391e-13 1 3.19817761667076 -8.82094977267804 2.65009601835876e-06 36.7654974733348 12.2323779859513 3.00558873471367 0.0027731634194704 -46.9439893288272 23.4510723041782 -2.00178434145475 0.0458048987295916 LACC1 other 0.0170215667259183 1 1 3.00558873471367 -2.00178434145475 3.64082538798265e-41 513.138394259685 34.9607264726323 14.6775666879055 8.39483243463891e-41 -306.657193700992 240.777571208403 -1.27361195713519 0.203393898637388 MAF1 other 5.35820272349407e-37 1 1.27064183730695e-36 14.6775666879055 -1.27361195713519 0.0206896586857073 -6.40738194217385 3.06642265981694 -2.08952993536656 0.0371256985932558 -52.7649655129462 28.688750643687 -1.83922144844454 0.0664294226373427 FCER1A other 1 1 1 -2.08952993536656 -1.83922144844454 9.71007936354573e-05 8.19107723693012 2.09352816181606 3.9125708391831 0.000103979880185554 -19.4745078453285 14.4183109711139 -1.35067886136902 0.177410504340348 WDR97 other 0.528228317376888 1 0.857626051770446 3.9125708391831 -1.35067886136902 0.00736142238063272 117.529643594755 38.6157846721336 3.04356481663231 0.00245241186399448 2.18178203448028 113.301276612836 0.0192564647081223 0.98464366617167 PCED1B other 1 1 1 3.04356481663231 0.0192564647081223 6.5207405317785e-09 193.198731685983 32.9358941912704 5.86590212380479 7.77689163498086e-09 59.2284669386279 68.2280890656571 0.868095058057852 0.385726494943224 APOBEC3B other 5.10639191043574e-05 1 8.36093619676792e-05 5.86590212380479 0.868095058057852 1.4551613057915e-28 15.4366110459339 1.28571526812422 12.006243861796 1.96590503333575e-29 13.0877191215263 5.14844266327477 2.54207339529767 0.0113132609948936 PIPOX other 1.96344914990447e-24 1 2.88280314088354e-25 12.006243861796 2.54207339529767 0.380353433512638 -3.37449507190175 2.70653371740248 -1.2467958740748 0.213016911645647 -6.88650288035719 7.12721948701716 -0.966225734018932 0.334366985000816 ATP8B5P other 1 1 1 -1.2467958740748 -0.966225734018932 0.0035856015236302 -8.96560388097078 2.66932740265345 -3.35875017506601 0.000839379546612378 -1.25012049261344 15.6854966189203 -0.0796991337274914 0.936506688588843 FOXS1 other 1 1 1 -3.35875017506601 -0.0796991337274914 0.013810041542477 -124.630357892491 57.018591262918 -2.18578458590478 0.0292609124259357 35.5813310866959 124.071979769024 0.286779747957073 0.774391174904605 CDH5 other 1 1 1 -2.18578458590478 0.286779747957073 6.44243330685805e-09 362.234204084617 90.7247083016517 3.99267422145045 7.42879373364466e-05 -1259.54796601431 304.209038542724 -4.14040283631287 4.01685897040669e-05 PCBP1-AS1 other 5.04764649592328e-05 0.465995809156881 0.621270019944703 3.99267422145045 -4.14040283631287 5.02383281017311e-10 1031.09960135158 156.267098745267 6.59831538200109 1.01291674509538e-10 81.7453415078446 608.535214379564 0.134331324755279 0.893191772076889 MYADM other 4.18284319775013e-06 1 1.16667750700085e-06 6.59831538200109 0.134331324755279 1.51280496828787e-22 211.326252238493 20.47808209742 10.3196310686301 9.3223921353168e-23 -118.297831181048 141.25868150272 -0.837455297774177 0.402738409460608 MROH1 other 1.8823832220406e-18 1 1.31352505186614e-18 10.3196310686301 -0.837455297774177 3.91654802010413e-07 224.247691858377 44.7523177713564 5.01086207431933 7.34278406813608e-07 -219.153390754792 155.183537723764 -1.41222061289064 0.158457844532082 SERTAD2 other 0.0027079013011 1 0.00712470338131244 5.01086207431933 -1.41222061289064 1.39398890691087e-05 21.6585627178582 27.5288281172864 0.786759342809002 0.431767258694389 -216.433233872335 54.4782652064837 -3.97283637891202 8.06396219665914e-05 AKAP5 other 0.0837229737490668 0.915179069698846 1 0.786759342809002 -3.97283637891202 0.0429974855116221 3.35176740553873 1.42893900178181 2.34563364941349 0.0193543155076314 -0.267834907287551 4.19503568293865 -0.0638456803542447 0.949116644047995 NKPD1 other 1 1 1 2.34563364941349 -0.0638456803542447 0.247321577809297 2.99547364319114 7.35997080516205 0.40699531594476 0.684171809074517 29.3117353845302 17.717706577794 1.65437525764578 0.0986291750687035 GIPC3 other 1 1 1 0.40699531594476 1.65437525764578 0.00699417137125131 137.181795483212 131.472719520613 1.04342403491322 0.297221436796952 -705.166408633881 281.298913537232 -2.50682236830093 0.0124765080595164 CITED4 other 1 1 1 1.04342403491322 -2.50682236830093 0.363686267170312 24.9972733913087 17.6359386087636 1.41740533043629 0.15694764794129 10.903677590866 72.0174073883955 0.151403361857525 0.879714716590689 ABCA13 other 1 1 1 1.41740533043629 0.151403361857525 1.60557699331454e-14 58.1080424403523 7.25732308658813 8.00681487472133 8.19330421762129e-15 -47.0727407700134 49.2352180798433 -0.956078648695675 0.339490858655718 TIGD5 other 1.62773395582228e-10 1 1.04448242166236e-10 8.00681487472133 -0.956078648695675 0.0257582740343924 5.37708286075219 1.99343298991148 2.69739835146952 0.0072063765625787 3.77077120803196 4.73519602314842 0.796328428558864 0.426190462403808 C1orf194 other 1 1 1 2.69739835146952 0.796328428558864 2.96667126268834e-08 29.0977075444421 4.87822739718812 5.96481163654126 4.43171819606751e-09 12.1723778653735 24.6391997943613 0.494024885830877 0.621489493147654 ZNF154 other 0.000223103349148268 1 4.80752789909403e-05 5.96481163654126 0.494024885830877 4.97838733721837e-12 168.897539584472 38.4838876751786 4.38878579550079 1.38003708222558e-05 -541.010558769906 113.761927332218 -4.75563812478313 2.56294418260314e-06 R3HDM2 other 4.57812499530601e-08 0.0319573510128786 0.122988904767944 4.38878579550079 -4.75563812478313 0.000130722090392774 52.707190016679 13.3750891127406 3.94069823179511 9.19173781665859e-05 119.493207012704 44.8579793299731 2.66381162944764 0.00795686317025046 B3GNT3 other 0.700408960324483 1 0.761995065000997 3.94069823179511 2.66381162944764 0.590203930920293 7.96377798184205 14.0286670519539 0.567678878709495 0.570488972331032 -38.2766237754862 50.4294533931175 -0.75901325911873 0.448175801035752 NRXN1 other 1 1 1 0.567678878709495 -0.75901325911873 5.23877517783177e-29 944.428430787363 87.8388611711348 10.7518291812476 1.60664213923392e-24 -1517.97077929627 530.671411826858 -2.86047212166677 0.00439730656927071 SEPHS2 essential 7.10430301865766e-25 1 2.29412431061212e-20 10.7518291812476 -2.86047212166677 0.188142760013685 2.07262186192769 1.86026247217089 1.1141556059608 0.265704441855272 -4.61977408277461 4.22699044056329 -1.0929227656732 0.274911454294088 GPBAR1 other 1 1 1 1.1141556059608 -1.0929227656732 2.93020776197399e-25 42.2495363294653 3.98500571841165 10.6021269014151 5.89397502863044e-24 -31.9210816450688 17.4043805551539 -1.83408318060571 0.0672000175214625 ZNF784 other 3.79901436339928e-21 1 8.3906628507583e-20 10.6021269014151 -1.83408318060571 3.68669679059773e-07 7.50159563118658 1.37753839202849 5.44565267624967 7.8318357008826e-08 10.9277146545988 9.60882913502666 1.13725767219281 0.255932173414378 ZNF648 other 0.00255718184825135 1 0.000805259119004911 5.44565267624967 1.13725767219281 3.36627393423826e-78 447.458682063049 21.7531774914409 20.5698078930817 7.346950424858e-70 -212.357395598987 72.6789762958826 -2.92185452275032 0.00362518857343584 C14orf119 other 5.23253620337996e-74 1 1.14009976692946e-65 20.5698078930817 -2.92185452275032 0.107599847656279 3.93918140306289 2.058789686161 1.91334813339202 0.0562261639051296 6.53444578124181 3.99952808710562 1.63380419862751 0.10287641108562 CCR8 other 1 1 1 1.91334813339202 1.63380419862751 3.70736860012225e-11 48.3785770155054 10.5745805415846 4.57498780450499 5.939119071636e-06 -141.629740707913 32.8146412464888 -4.31605330206275 1.89642471057966e-05 BBS10 other 3.26952836844781e-07 0.225048720404489 0.0544082698152574 4.57498780450499 -4.31605330206275 2.16466327789365e-35 116.726459452783 8.96272474001487 13.0235461691295 7.50154417577181e-34 -71.3820573788704 39.1075139178984 -1.8252772991075 0.0685197239634025 FIZ1 other 3.09763315066582e-31 1 1.11727998953945e-29 13.0235461691295 -1.8252772991075 5.1233163578333e-39 929.094240787811 64.685526308849 14.363247758884 1.9974340706872e-39 -206.892630344353 436.367351750498 -0.474124907636648 0.635617401326883 PUF60 essential 7.47081991299252e-35 1 3.01632519014474e-35 14.363247758884 -0.474124907636648 0.00562681283498911 -59.4420399807922 26.9494987531413 -2.20568258153089 0.0278322370259802 -321.924628504205 118.812103711731 -2.70952721521771 0.00695479385053926 SSC5D other 1 1 1 -2.20568258153089 -2.70952721521771 3.11817055615961e-22 293.755959256132 30.1622032535805 9.73920760318661 9.98839069901721e-21 -228.453692219438 182.222523960114 -1.25370721058305 0.210502212956034 DCTPP1 other 3.85873606324752e-18 1 1.38259304055796e-16 9.73920760318661 -1.25370721058305 1.11310340095857e-21 70.5587379167607 7.51250867900992 9.39216724153717 1.74450220681743e-19 -80.5574353590275 45.3862166915457 -1.77493171344316 0.0764841289953143 ZNF771 other 1.36277249379358e-17 1 2.38665346914693e-15 9.39216724153717 -1.77493171344316 5.61134742814363e-10 181.219966085482 55.4431976271161 3.26856988488073 0.00115010187686705 -432.969856553076 112.486930573955 -3.84906810367999 0.000132839295866857 TSHZ1 other 4.66134630855892e-06 1 1 3.26856988488073 -3.84906810367999 4.28834533515316e-107 56.6893855234195 2.04534539411963 27.716289721238 4.33701219231123e-106 9.19541321148242 7.53015681091787 1.22114498308324 0.222560102383774 PSTK other 6.70311259337791e-103 1 6.78048486145938e-102 27.716289721238 1.22114498308324 2.0518152646276e-12 79.4653754481737 18.3751891312441 4.32460177038698 1.81971900829154e-05 -174.212886727816 40.5572498131061 -4.29548077176374 2.06675009102648e-05 SOCS4 other 1.91393327884463e-08 0.244723878278446 0.160408230580899 4.32460177038698 -4.29548077176374 7.0196471860031e-17 225.665562324335 51.5561869449911 4.37708014685247 1.4454829445496e-05 -541.012401507877 104.574570069751 -5.17346044212302 3.24845671174705e-07 ZADH2 other 7.68370580979899e-13 0.00420772597872595 0.128546798258796 4.37708014685247 -5.17346044212302 4.75816599762091e-29 80.9660283641216 7.55795248895789 10.7126934817879 2.27503403918701e-24 -135.259335077828 45.6607618127181 -2.96226628089576 0.00319114589218093 ZNF48 other 6.45492799237252e-25 1 3.24488105009243e-20 10.7126934817879 -2.96226628089576 0.251609299226808 -4.83670932449112 4.36376607453767 -1.10837960648557 0.268193153265135 -21.083724324815 16.5549886985829 -1.27355715601423 0.203370355487447 C3orf80 other 1 1 1 -1.10837960648557 -1.27355715601423 0.191369596832951 1.05761234002557 0.919140574151685 1.1506535232673 0.250387873361018 5.52045715514493 3.50175674471558 1.57648219382335 0.115504711353766 TMEM150B other 1 1 1 1.1506535232673 1.57648219382335 2.43138740268789e-06 12.7317382256361 2.47410729210959 5.14599276524512 3.74964802457337e-07 10.2271767753975 7.09979673513889 1.44048867269402 0.150317436073752 ANKRD18A other 0.0156824487473369 1 0.0037080269315006 5.14599276524512 1.44048867269402 1.41458213466794e-07 15.8744434656255 2.83817195010089 5.59319299349049 3.53718289552413e-08 -3.25203804737774 10.8571612788984 -0.299529311929655 0.764650826097238 TMEM86B other 0.00101312372484918 1 0.000369777099898093 5.59319299349049 -0.299529311929655 0.000486476097476667 23.0051428604319 6.03444599328365 3.81230404349243 0.000153820219440539 -0.285564736151378 36.5666378270096 -0.00780943376589161 0.993771969730084 SEPT1 other 1 1 1 3.81230404349243 -0.00780943376589161 5.10741896077646e-19 71.421881818529 11.6110980444828 6.15117377744184 1.49479009718039e-09 -61.9728164090709 18.922979626251 -3.27500307209012 0.00112409433551201 TRNAU1AP other 5.90826225382621e-15 1 1.65099566233574e-05 6.15117377744184 -3.27500307209012 2.90563870301718e-27 284.962665535729 26.4312686229873 10.7812708349495 1.30861829022787e-24 -327.783232354174 116.109955717501 -2.82304157579459 0.00493827797998853 EXOC3 essential 3.86740511371587e-23 1 1.86949208941954e-20 10.7812708349495 -2.82304157579459 2.94411844452547e-33 18.830081168804 1.42782661336177 13.1879326191219 2.05307567029268e-34 23.4734673927055 6.88078254145288 3.4114531670331 0.000697068965471854 TDRD6 other 4.14649641726968e-29 1 3.06318890007668e-30 13.1879326191219 3.4114531670331 0.25034002261257 -2.81902165561317 1.74546223711643 -1.61505737315194 0.106885628575869 -3.95614672786106 3.33919893474545 -1.18475922075084 0.236636731803692 CSNK1A1L other 1 1 1 -1.61505737315194 -1.18475922075084 0.339119915609186 -238.368313997137 250.625467131249 -0.951093744484902 0.341983067305828 -705.159062299979 509.448953479193 -1.38416039032805 0.166882171236928 ACTA2-AS1 other 1 1 1 -0.951093744484902 -1.38416039032805 3.32750146845231e-06 97.2501768216713 20.0589606927803 4.84821613198904 1.64259740069266e-06 302.079163981212 144.93095686423 2.08429703713469 0.0376150631569494 LYNX1 other 0.0211695643422936 1 0.0155981049169775 4.84821613198904 2.08429703713469 0.186792017300017 4.39759407969973 2.45378446604856 1.79216803290852 0.0736596020683255 5.87177970569495 4.89740346110721 1.19895772368476 0.231064467671961 TH other 1 1 1 1.79216803290852 1.19895772368476 0.137527053111848 -15.4373570448308 23.1515073610964 -0.666797060081349 0.505186569674508 -128.691565125177 64.6473738477829 -1.99066965083826 0.0470207960072721 FAR2P1 other 1 1 1 -0.666797060081349 -1.99066965083826 8.72108332965564e-33 149.805089702424 14.4884288829429 10.3396366102047 5.38462425061735e-23 -269.862849427743 66.3182221707225 -4.06921115486233 5.4176713652585e-05 FAHD1 other 1.22452731031695e-28 0.623682327568559 7.6030894418717e-19 10.3396366102047 -4.06921115486233 1.95899205640164e-17 127.981492000379 19.3599264003053 6.61063938747002 9.76697225687475e-11 -29.3318127671218 39.84557928141 -0.736137190024657 0.461989681827059 TDRP other 2.17663607386786e-13 1 1.12554588288225e-06 6.61063938747002 -0.736137190024657 6.11201139514006e-09 321.837877691059 66.7698815862029 4.82010556324788 1.86595565901644e-06 -116.13766846043 108.81702178919 -1.06727483026895 0.286322897066127 RCC1 essential 4.79120573265029e-05 1 0.0176612703125906 4.82010556324788 -1.06727483026895 0.433646450766378 150.989396747556 118.94762261767 1.26937717143685 0.204862638402771 49.7166987555832 720.781102604145 0.0689761407117353 0.945034577497447 MYLPF other 1 1 1 1.26937717143685 0.0689761407117353 1.06254292900576e-20 154.400760696383 21.414180118181 7.21021117055486 1.90391682068249e-12 -243.926320066238 53.0674266554273 -4.59653567997708 5.35861575354991e-06 PRKRA other 1.27558278627141e-16 0.0657555739118109 2.30145465284099e-08 7.21021117055486 -4.59653567997708 0.000539974645466418 20.5062042300134 9.97914856010854 2.0549051962195 0.0403979981996569 -48.1494380645186 22.2518273665183 -2.16384197447836 0.0309409646173411 HERC2P3 other 1 1 1 2.0549051962195 -2.16384197447836 1.96124453701556e-07 34.0915680978942 21.5611903798596 1.58115426362263 0.114430459664486 -444.640279444505 89.6577404869502 -4.95930721686237 9.50010068511795e-07 ZNRF2 other 0.00138875725666072 0.012080328031196 1 1.58115426362263 -4.95930721686237 5.038963770097e-13 49.4257795513996 6.49574404611611 7.60894813596481 1.22530937500545e-13 0.292655974660001 27.4804602917681 0.0106496023557388 0.991506911578738 ZNF816 other 4.81271429681964e-09 1 1.52281449125677e-09 7.60894813596481 0.0106496023557388 0.0017902339042482 29.2269473206222 53.0475061931525 0.550957988754518 0.581890344077536 -466.652151490481 143.198744543312 -3.25877264482118 0.00118935465918097 FGD6 other 1 1 1 0.550957988754518 -3.25877264482118 0.214775981978199 -7.96237527313898 7.01015943908697 -1.13583369141973 0.256526317878797 -25.8836656728421 15.9096552815419 -1.62691555629567 0.104334087438665 ADGRD2 other 1 1 1 -1.13583369141973 -1.62691555629567 6.14474611922702e-35 445.124511956955 40.6689516717871 10.9450697315551 2.58587930937014e-25 -435.319205060137 92.4066380106013 -4.71090837662761 3.14196816890567e-06 OAZ2 other 8.76179349140581e-31 0.0389855410397815 3.7097024572224e-21 10.9450697315551 -4.71090837662761 3.05380097517422e-62 223.908422949036 14.1966134816348 15.771960209996 2.34597992405406e-46 -130.719891463712 33.1753612043995 -3.94027033069279 9.20975701637159e-05 CCDC43 other 4.70285350176831e-58 1 3.5804345600913e-42 15.771960209996 -3.94027033069279 3.08693865540661e-20 47.0235258925481 5.36838218037591 8.75934766053771 2.55742240098544e-17 -8.8224707218636 12.5659950423211 -0.702090896276047 0.482926105234437 MEIOC other 3.67253091833725e-16 1 3.40469644243192e-13 8.75934766053771 -0.702090896276047 2.65906807951137e-08 29.6014492944187 7.46319765252996 3.96632257010962 8.28671706789217e-05 -44.5462101244159 17.4647120875309 -2.55064096683393 0.0110283279900295 FZD2 other 0.000200600095918338 1 0.690034930243381 3.96632257010962 -2.55064096683393 2.0184357295235e-07 84.1997594392905 15.2527191976147 5.52031138503214 5.2416928700863e-08 107.824228397979 36.1532806547113 2.98241892424023 0.0029877439773429 TIGD2 other 0.00142703406077311 1 0.000543878052200154 5.52031138503214 2.98241892424023 0.0381575871296492 0.406625506188893 3.88872053143167 0.104565371284007 0.916759305146173 41.2631982859551 16.3382852740848 2.52555256526249 0.0118350525209215 CCDC129 other 1 1 1 0.104565371284007 2.52555256526249 0.243271535794179 -34.0904545279741 30.7160600209689 -1.10985766093378 0.267549823455784 104.7275768243 101.094749167391 1.03593487977198 0.300691945358487 HCLS1 other 1 1 1 -1.10985766093378 1.03593487977198 0.21496519626777 138.684252503446 79.6391320913723 1.74140838632356 0.0821836056135127 44.4038132558722 334.186958734891 0.13287117314203 0.894344946526045 MTURN other 1 1 1 1.74140838632356 0.13287117314203 2.89595641617476e-33 613.573427565532 58.7963303599802 10.4355735095869 2.40354133043961e-23 -652.877465526238 133.595064357056 -4.88698791881494 1.35248734199744e-06 ZNF609 other 4.07924420782377e-29 0.0170805626420856 3.40557771109989e-19 10.4355735095869 -4.88698791881494 2.86260532383182e-29 769.455184744528 63.7691516250219 12.0662603333523 8.06242442236767e-30 -458.08329582061 282.078975417683 -1.62395405450659 0.10497460995063 PAK2 other 3.89113941668459e-25 1 1.18412827491314e-25 12.0662603333523 -1.62395405450659 1.07904491311159e-27 10.3117286017886 14.0783027758996 0.73245537945391 0.464204968228325 -261.404753402359 26.1899193092466 -9.98112099223106 1.15899617674031e-21 CCDC66 other 1.44343838026937e-23 1.79366248312331e-17 1 0.73245537945391 -9.98112099223106 0.11809586065768 57.0611791327526 28.1434115812458 2.02751464469848 0.0431106133391942 77.8131202137037 59.5653018796281 1.30634980027385 0.192001320110534 ATP5EP2 other 1 1 1 2.02751464469848 1.30634980027385 1.66902224376494e-13 520.910328410536 67.6097333798399 7.70466473346371 6.2545169636823e-14 -128.370346451223 233.093100379446 -0.550725638134515 0.582047850832527 MCFD2 other 1.62846500324146e-09 1 7.82627707665567e-10 7.70466473346371 -0.550725638134515 1.16134087936601e-28 48.8342607797542 4.82306488553795 10.1251511100721 3.52468140854191e-22 -36.3137550822324 13.8843590248309 -2.6154433933384 0.00916034252237432 HARBI1 other 1.56920379619935e-24 1 4.94019346221234e-18 10.1251511100721 -2.6154433933384 1.01100550482894e-22 44.8329550548193 7.28497864301948 6.15416424010777 1.4618307751078e-09 -48.476191354813 13.4595812968851 -3.60161213677811 0.000345101666602117 C11orf71 other 1.26213927222845e-18 1 1.61576155572665e-05 6.15416424010777 -3.60161213677811 0.000355388946675248 23.301537616196 6.41014091752255 3.63510536133451 0.000304546638794892 40.9504904177693 16.204587534697 2.52709242552992 0.0117865407358747 TPRXL other 1 1 1 3.63510536133451 2.52709242552992 0.787786754394209 -0.242488348041436 43.5658796931475 -0.00556601518778873 0.995561044750845 -62.5540288243278 95.4597565315275 -0.655292147153844 0.512559246664381 GAS1 other 1 1 1 -0.00556601518778873 -0.655292147153844 1.55226506100265e-06 -1.45758141895052 39.2305275880405 -0.0371542650217854 0.970376047349831 -324.994202647845 70.7861145772621 -4.59121403383595 5.51415432550253e-06 ARHGAP45 other 0.0101797542700554 0.067603532030661 1 -0.0371542650217854 -4.59121403383595 2.61509720070956e-32 31.307314111344 2.71135904640841 11.5467238294445 1.03354964637034e-27 -42.1359186832601 13.3113491455347 -3.16541307891353 0.00163611955302074 ZNF571 other 3.65355229911133e-28 1 1.50278118582248e-23 11.5467238294445 -3.16541307891353 1.15179790508492e-07 5.59747465921775 2.93313063549211 1.90836186819842 0.0568885329260978 -44.5399552916018 9.11163585111089 -4.88825014732908 1.3532333700952e-06 GLIPR1L2 other 0.00082940967145165 0.0170872777641921 1 1.90836186819842 -4.88825014732908 6.61224755423806e-06 -17.2402338328778 43.5789183454097 -0.395609493935358 0.692549956297004 -406.086145902337 86.5822955525417 -4.69017532176549 3.46532721760265e-06 MIGA1 other 0.0407919939876257 0.0428868896450504 1 -0.395609493935358 -4.69017532176549 0.00194513348806126 61.9055181729865 188.834573909445 0.327829363507729 0.743179576084163 -1830.60001676493 560.989176780336 -3.26316458950461 0.00117804502663868 NRIP1 other 1 1 1 0.327829363507729 -3.26316458950461 0.351515474016922 0.557371341737938 1.85470284802138 0.30051786588485 0.763897405495822 -7.21934092508077 5.69028658148029 -1.26871306422017 0.205088027798662 BHLHA15 other 1 1 1 0.30051786588485 -1.26871306422017 1.46579076481496e-09 62.8197291422964 10.6701248947335 5.88744084647996 6.92365016080104e-09 156.067661034485 36.5258689724501 4.27279803123096 2.28450139316412e-05 RNF182 other 1.18992894287678e-05 0.269548319379435 7.46231014331136e-05 5.88744084647996 4.27279803123096 0.000269887904198623 146.207789429176 40.4338157530058 3.61597802993173 0.000327634337690722 844.220398153963 427.791250586166 1.97344007619885 0.0489615573974972 TSPYL5 other 1 1 1 3.61597802993173 1.97344007619885 0.477926332306417 0.991702697691593 1.27501286970174 0.777798186400721 0.437050079028739 3.36466372536785 2.96100837568327 1.13632360955124 0.256356915246077 FUT7 other 1 1 1 0.777798186400721 1.13632360955124 0.0148607818816036 179.545655591491 103.379260439113 1.73676668636296 0.0830050251710824 -726.787466449067 411.250946272007 -1.76726028970243 0.0777557498029198 HIST1H2AC other 1 1 1 1.73676668636296 -1.76726028970243 0.484049355830379 2.61820926553348 3.3269242590853 0.786975915782744 0.431644437580461 -9.2242294782615 12.6669422198962 -0.728212801332021 0.466801933037346 SKIDA1 other 1 1 1 0.786975915782744 -0.728212801332021 0.753606268468289 9.57881879505218 12.9547551016935 0.739405625182369 0.459985630506703 17.3433808898072 51.2497371898545 0.33840916735941 0.735187878350319 HIST1H2BC other 1 1 1 0.739405625182369 0.33840916735941 0.138550217991188 13.9685727021298 8.31445956709477 1.68003375197249 0.0935280477893317 -40.5854516727375 36.7796496542009 -1.10347575505255 0.270311202824512 MB21D2 other 1 1 1 1.68003375197249 -1.10347575505255 0.00715998671557374 11.6663877414598 55.7412267496038 0.209295496740082 0.834298752956461 -587.48079837642 192.143761591624 -3.0575064915458 0.00234560719553782 SSTR2 other 1 1 1 0.209295496740082 -3.0575064915458 5.20453123372847e-35 36.7734887613083 8.75752918735418 4.19907121912982 3.13544120528492e-05 -164.000094368533 16.4586881944865 -9.9643478526722 1.40244209385494e-21 ZNF594 other 7.4253047111604e-31 2.16985840761237e-17 0.271536489192019 4.19907121912982 -9.9643478526722 0.00113171940627787 60.818685024594 42.8737853278806 1.41855179241764 0.156602356754666 -217.8952042869 83.366582750003 -2.61369960359677 0.00920477600941784 PCGF5 other 1 1 1 1.41855179241764 -2.61369960359677 2.81491015914897e-09 44.9723107086492 7.87936511717031 5.70760588447004 1.88651949514572e-08 101.367024616586 22.5327159503133 4.4986598526387 8.36889511148188e-06 PRF1 other 2.24939470817594e-05 0.101556542177833 0.000199706953756126 5.70760588447004 4.4986598526387 0.0131708081690379 -3.36690382944458 1.2707097321508 -2.64962465011246 0.00829600320737282 -7.18518346623903 3.01585196086881 -2.38247220336674 0.0175445035846068 OR2A4 other 1 1 1 -2.64962465011246 -2.38247220336674 0.00277446081180032 -8.05832616076426 3.37608163535347 -2.38688723530246 0.0173394254610135 -22.3960305397745 6.65731407994668 -3.36412407028179 0.000823115850537009 MAB21L1 other 1 1 1 -2.38688723530246 -3.36412407028179 3.97023648105737e-07 39.6612906111043 9.088142531729 4.36407004760728 1.53261468381739e-05 238.087601161719 70.6647950026756 3.36925340479236 0.000808056381518448 YOD1 other 0.00274383043205875 1 0.13595824860144 4.36407004760728 3.36925340479236 0.465840887382503 137.143879936867 112.240698343888 1.22187301006164 0.222308197368492 -101.850310419979 1129.30500739545 -0.0901884873909126 0.928172093718979 TMEM64 other 1 1 1 1.22187301006164 -0.0901884873909126 2.80760206769764e-05 35.6037518306437 145.294082089719 0.245046125200463 0.806514155654586 -1239.02871176205 311.752487566346 -3.9743987976948 8.01829095954817e-05 SHISA2 other 0.163430516360679 0.910236389727908 1 0.245046125200463 -3.9743987976948 4.25047819779918e-16 35.8374640381882 4.19478912354462 8.54332911207353 1.33160677955297e-16 52.5510305603587 13.8883801496914 3.78381279846565 0.000171689057859801 S1PR5 other 4.54546138472644e-12 1 1.75119607579011e-12 8.54332911207353 3.78381279846565 0.000778957176439317 24.3546785947149 6.39481782875673 3.80850232905694 0.00015573506738388 34.9719387261446 34.172283115988 1.02340070774441 0.306573294747713 SMG1P3 other 1 1 1 3.80850232905694 1.02340070774441 1.7920825466627e-07 160.001534930445 32.4955794937182 4.92379386437393 1.12968363870489e-06 -0.4400967703017 53.6984886678733 -0.00819570124261245 0.993463876536395 GPR157 other 0.00127327464940385 1 0.0108381848297347 4.92379386437393 -0.00819570124261245 0.00114393225849914 92.6409229945908 30.7982282131063 3.00799521172348 0.00275143279168934 187.020072718878 59.417861087848 3.14753963361914 0.0017367219196467 PIPSL other 1 1 1 3.00799521172348 3.14753963361914 2.89351610970617e-08 2.6043369001182 2.63205231815598 0.989470035285168 0.322875551920488 -32.6006747703337 6.39282004209923 -5.09957648669061 4.7160395117283e-07 WDFY3-AS2 other 0.000217852827899778 0.00607438259584633 1 0.989470035285168 -5.09957648669061 2.92866567327864e-18 131.591946025786 15.0780527925007 8.72738329257173 3.31949790472659e-17 59.9367866985219 33.0639048794609 1.81275584106081 0.070429826938823 SLC36A4 other 3.32696420484453e-14 1 4.41161271538164e-13 8.72738329257173 1.81275584106081 8.70461272788279e-17 473.54434948145 63.0058156313168 7.5158831726333 2.43767528584858e-13 -68.04575573389 128.036512546786 -0.531455866614809 0.595326422330565 ZDHHC20 other 9.4984734086657e-13 1 3.00931014038008e-09 7.5158831726333 -0.531455866614809 0.0586117886240985 -46.9069366214928 70.1883100165782 -0.66830126855047 0.504243054414444 -413.030809619367 174.312063384308 -2.36949068010716 0.0181832210209751 ANKRD30B other 1 1 1 -0.66830126855047 -2.36949068010716 0.313433745311831 -0.864386987433889 2.91474646813282 -0.296556491922816 0.766917902893972 7.97961775528478 6.36116666572904 1.25442677021421 0.210223660978001 OR51E1 other 1 1 1 -0.296556491922816 1.25442677021421 1.00458624452961e-39 53.573619075011 9.19131108969251 5.82872438460826 9.56813935345332e-09 -163.013516531935 16.8222663742118 -9.69034212784973 1.35677459737414e-20 ZFP3 other 1.46981013437128e-35 2.09377455866778e-16 0.000102474772475485 5.82872438460826 -9.69034212784973 0.815420092935733 9.58362056547768 16.8711675863719 0.568047262669544 0.570237686745644 18.4324736046363 36.7821373021158 0.501125681012996 0.616485756726037 ARSJ other 1 1 1 0.568047262669544 0.501125681012996 0.0348046417941715 15.3138035552964 8.48773289831242 1.80422778835808 0.0717578865355686 -34.3245991426432 26.2926335475212 -1.30548349523851 0.19228938451624 HOXC9 other 1 1 1 1.80422778835808 -1.30548349523851 2.37002789540527e-26 844.738653614299 78.2691452053065 10.7927415253926 9.71822050211012e-25 -60.9747749162012 203.600026600976 -0.299483138259615 0.764685821865443 PPA1 essential 3.1199047215115e-22 1 1.38951116739171e-20 10.7927415253926 -0.299483138259615 1.21401266837045e-08 317.936926865514 58.8664643875751 5.40098560654546 9.98575761900099e-08 -242.954222105086 182.351918341876 -1.3323370782949 0.183316666837248 HOXC10 other 9.34061347044222e-05 1 0.00101974556805238 5.40098560654546 -1.3323370782949 2.66914815370219e-13 95.5113102690162 18.2266877572328 5.24019018382069 2.31629427285884e-07 -206.321187227726 54.7072634185558 -3.77136735298198 0.000180564542968534 PSMG4 essential 2.5829346683376e-09 1 0.00231722079056798 5.24019018382069 -3.77136735298198 0.877603690671096 -1.42439728694986 5.77937209553002 -0.246462290955715 0.805421094740166 -23.8745796406182 50.4897576724958 -0.472859857943502 0.636510439648285 BHLHE22 other 1 1 1 -0.246462290955715 -0.472859857943502 0.22697876681376 10.3752887716104 6.45351500014182 1.60769577065869 0.108482024659433 15.5241800642999 28.2512888405213 0.54950342803594 0.582885514024746 MAP6D1 other 1 1 1 1.60769577065869 0.54950342803594 2.90117518175192e-14 31.5479553326786 4.95008481907051 6.37321510353481 4.0434766480748e-10 -59.4675949381633 18.1294188886926 -3.28017104702972 0.00110603379578077 ZNF443 other 2.9119095299244e-10 1 4.57155469831337e-06 6.37321510353481 -3.28017104702972 0.677875161521484 0.943456355273638 2.55876945442178 0.368714873332282 0.712484505950986 -12.1592221280363 15.7577380262407 -0.77163499658314 0.440667548875549 GREM2 other 1 1 1 0.368714873332282 -0.77163499658314 1.82974719966452e-09 13.0639234220241 3.8095239207699 3.42927979813915 0.000652675768960566 -54.8498723480476 11.8341114139732 -4.63489572045802 4.50914559862248e-06 CAPS2 other 1.4797165603687e-05 0.0555256189014372 1 3.42927979813915 -4.63489572045802 3.63656304068056e-13 18.0780708415691 3.49455532775211 5.17321065086638 3.23665271460356e-07 -86.4992784567347 18.4612164781785 -4.68545930106928 3.53086910425997e-06 ZNF792 other 3.49691901991843e-09 0.0436803816888 0.00321237781924403 5.17321065086638 -4.68545930106928 1.61481751881929e-14 271.594565529109 36.5988855234612 7.4208425104914 4.81542645107552e-13 -240.172786834616 128.349637817637 -1.87123852406862 0.0618765788466298 CUEDC1 other 1.63677903707523e-10 1 5.89648968934197e-09 7.4208425104914 -1.87123852406862 7.44724262671117e-58 280.02602696777 19.4848475112782 14.3714764411518 7.70540786973927e-40 -519.102858528056 63.6594978119358 -8.15436621981531 2.51089920879671e-15 KCTD2 other 1.14128993254349e-53 3.78141420844784e-11 1.1643641831963e-35 14.3714764411518 -8.15436621981531 2.99628669836351e-06 26.6407002238222 37.8343932501586 0.704139750508898 0.481647048443687 -328.399272874602 73.2860356426173 -4.48106204674593 9.05947314421739e-06 D2HGDH other 0.0191402794291461 0.109673981883896 1 0.704139750508898 -4.48106204674593 0.383882097592366 -27.7460115000234 96.7693068069689 -0.286723263972221 0.774434608826397 -337.899633404224 244.071066997687 -1.38443133617073 0.166800350818369 OXTR other 1 1 1 -0.286723263972221 -1.38443133617073 1.04089260422208e-30 166.527242831899 21.2696898011583 7.82932164919634 2.62487211335517e-14 -161.976839768214 46.9802241098344 -3.44776643443698 0.000609488673702349 CMTR2 other 1.43310093749297e-26 1 3.31153865820888e-10 7.82932164919634 -3.44776643443698 5.06857471792028e-32 739.728494728969 57.8319003657834 12.7910113631098 1.44047107485428e-32 -161.978879820364 393.880397390911 -0.411238743774311 0.681075463998059 FAM83H other 7.06610001425266e-28 1 2.13665074533135e-28 12.7910113631098 -0.411238743774311 3.85448138278782e-25 20.4524351127086 1.84417475570599 11.0902912261582 7.44345334918394e-26 -26.1538561436419 20.8750460242601 -1.25287657393651 0.210801036501955 ZNF572 other 4.98692801305088e-21 1 1.07126180601455e-21 11.0902912261582 -1.25287657393651 1.78478507289702e-10 27.2237806593961 4.3640378032567 6.23820917387108 8.88980203588139e-10 42.7074099434039 9.77919620164512 4.36716976147992 1.50681094816069e-05 ST20 other 1.52313558121031e-06 0.179973499648312 9.91568519082211e-06 6.23820917387108 4.36716976147992 4.30027322664387e-52 545.633135409271 37.895827665682 14.3982377221804 5.55339900457812e-40 -123.057974859876 79.8631594647357 -1.54086033766563 0.123939817477576 PITPNB other 6.52781475804539e-48 1 8.39396259541983e-36 14.3982377221804 -1.54086033766563 3.2692980576388e-22 42.9661619830455 15.3212847209551 2.80434459417625 0.0052304674538057 -184.629694180657 25.7087219803406 -7.18159752638981 2.39767087165778e-12 LRRC57 other 4.04412169729919e-18 3.50995038901983e-08 1 2.80434459417625 -7.18159752638981 2.8999569736603e-27 270.256643712193 24.3191319186301 11.1129231346107 5.64115650444944e-26 -145.646249374059 127.923016542383 -1.13854608272002 0.25539831491023 MRPL14 essential 3.86013272763923e-23 1 8.12552182900898e-22 11.1129231346107 -1.13854608272002 9.54624136266828e-06 20.615461847257 5.16748919544246 3.98945427219066 7.53267590086646e-05 -17.4288727140568 12.2902114645963 -1.41811007599529 0.156733311755889 GPR137C other 0.0581938873468258 1 0.62950572503541 3.98945427219066 -1.41811007599529 1.21705338167786e-17 19.5791152284677 4.75325859320549 4.11909321669453 4.40028723050012e-05 -71.9397488429342 11.4960981734339 -6.25775352277159 7.95991154027714e-10 BBS12 other 1.36078738605401e-13 1.11773077848572e-05 0.3756965237401 4.11909321669453 -6.25775352277159 7.05203428483232e-24 63.5475685416855 6.21086431199878 10.2316787727785 1.41768585865847e-22 -31.0722811556202 27.7626787426553 -1.11921048554583 0.263548863071158 ZFP82 other 8.95608354173704e-20 1 1.99397516020314e-18 10.2316787727785 -1.11921048554583 0.00564786739794363 7.74560487769289 2.75803295069617 2.80838010863423 0.00516036798848697 -5.64365873058618 8.53241926736555 -0.66143710871919 0.508615730335966 LSMEM1 other 1 1 1 2.80838010863423 -0.66143710871919 8.77181121326003e-14 1399.46763752991 257.457503299987 5.43572286529658 8.25693647503825e-08 -794.274662856289 564.54830161743 -1.40692064891648 0.160023010182677 NQO1 other 8.64725149403173e-10 1 0.000847822237256927 5.43572286529658 -1.40692064891648 1.05322825301765e-16 157.156146515558 17.818265489813 8.81994639744292 1.57462396656086e-17 66.048321660385 42.2866077711244 1.56192054983153 0.11889145360054 AEN other 1.14738685883743e-12 1 2.10196553296209e-13 8.81994639744292 1.56192054983153 1.96610014994553e-14 37.2362377212342 7.03544794481371 5.29266054035458 1.74893232164847e-07 -82.3487821511326 20.5353452622092 -4.01009971342813 6.91425895499773e-05 FKRP other 1.98576115144499e-10 0.788709518996592 0.00176099995466784 5.29266054035458 -4.01009971342813 1.30691093170161e-38 356.661893150025 26.037802665068 13.6978491517841 6.25800391093023e-37 -52.542592003083 94.4450280511939 -0.556329889325696 0.578212864605337 TRAPPC5 other 1.90181678781219e-34 1 9.39263806991518e-33 13.6978491517841 -0.556329889325696 6.82311636280778e-18 10.8663024793338 15.6798211803244 0.693011887977984 0.48860622285093 -227.518748343181 28.5847710122109 -7.95943924987153 1.06012238298917e-14 RPH3AL other 7.68282902452156e-14 1.58732124404968e-10 1 0.693011887977984 -7.95943924987153 6.76228769735454e-10 29.1893245029888 7.59401540717809 3.84372732183269 0.000135855873003072 -100.568122190983 24.7361801247877 -4.06562863318599 5.51590007726376e-05 SLC25A42 other 5.58362095170564e-06 0.63449398588765 1 3.84372732183269 -4.06562863318599 0.87019978707003 0.24418014403518 0.866779258395999 0.281709722135071 0.778273822850686 3.71444430232428 8.42397957983827 0.440937002175828 0.65943475436682 FCRL6 other 1 1 1 0.281709722135071 0.440937002175828 5.2927569365694e-56 138.637188439037 8.28578321329554 16.7319352763872 6.16580214536597e-51 -77.4128921338916 26.2389237777943 -2.95030744360808 0.00331230207804215 METTL23 other 8.08521549630341e-52 1 9.45895707120594e-47 16.7319352763872 -2.95030744360808 8.9531720096972e-36 142.166549496138 13.6393965725392 10.4232286773132 2.5931775334506e-23 -280.827184575406 40.4310450521369 -6.94583046798004 1.07974470571721e-11 SLC26A11 other 1.28433252479106e-31 1.56703349140739e-07 3.67193938736605e-19 10.4232286773132 -6.94583046798004 2.63678526986439e-09 70.3354361276258 101.662144836473 0.691854733546715 0.489322113587922 -1027.47459111311 194.184519471355 -5.29122812627028 1.76085446678597e-07 HIGD1A other 2.11101028705343e-05 0.00230425415523612 1 0.691854733546715 -5.29122812627028 2.88777724730405e-07 87.6593716872457 16.8283256863749 5.20903703202151 2.77345447228301e-07 -157.041327371263 115.702800156503 -1.35728199454848 0.175300306428202 MAPK15 other 0.00201706668111 1 0.00276291534528833 5.20903703202151 -1.35728199454848 1.92462862831834e-26 238.643622631517 44.2473258547953 5.39340215530006 1.07291178928232e-07 -817.110771025234 103.323775254307 -7.90825508469962 1.71469632627968e-14 EHMT1 other 2.53569821780942e-22 2.56364247742075e-10 0.00109318982209976 5.39340215530006 -7.90825508469962 0.0488314392998652 281.026834466478 480.66672004368 0.584660478347535 0.559019770301445 4771.3818235824 1985.76263971221 2.40279564544224 0.0166060579692332 ADIPOQ other 1 1 1 0.584660478347535 2.40279564544224 2.07613350136618e-08 -200.769110921853 80.9458942694672 -2.48028776176709 0.0134296330533343 -1081.71207636546 178.924666816629 -6.04562856318774 2.76927504294117e-09 F2R other 0.000157661578093748 3.84098448455941e-05 1 -2.48028776176709 -6.04562856318774 0.00650898294815208 177.366461663941 55.6698328777667 3.18604264635358 0.00152826265251666 192.980914855661 291.617444605521 0.661760530535859 0.508415603058645 MUC16 other 1 1 1 3.18604264635358 0.661760530535859 1.41062960501343e-09 759.916005414532 162.402215049422 4.67922192553393 3.64489126059071e-06 -1070.53075435541 424.024628952748 -2.52469003274502 0.0118653749079184 NPM1 essential 1.14613655407341e-05 1 0.0338610398108877 4.67922192553393 -2.52469003274502 1.20038945213618e-66 851.007323111108 42.1881972253306 20.1716920627305 7.28533454647281e-68 686.753869221726 240.411950659433 2.8565712616948 0.00444739768344182 DHTKD1 other 1.8546017035504e-62 1 1.12966397477607e-63 20.1716920627305 2.8565712616948 0.504421610197984 -7.29872383852039 7.02581090949757 -1.03884433164205 0.299369398379532 -36.6478857149627 55.1364912526331 -0.664675696301451 0.506558364640272 PENK other 1 1 1 -1.03884433164205 -0.664675696301451 0.160459817674648 21.5878475051924 22.5691685780666 0.956519396384504 0.339235545399115 -213.878338405497 134.142136239951 -1.59441577717918 0.11142479846783 HIST3H2A other 1 1 1 0.956519396384504 -1.59441577717918 3.83819276120713e-28 73.2191508207365 9.72550500957363 7.52857057280427 2.17665149573753e-13 -193.123038627889 30.3903066918387 -6.35475780439398 4.45347807604502e-10 ZNF746 other 5.15776343251014e-24 6.28697499995275e-06 2.69034124873159e-09 7.52857057280427 -6.35475780439398 1.48548721517567e-17 -139.105099784865 191.687939236189 -0.725685196153453 0.468343275695781 -2932.15762872762 344.16382294661 -8.5196567251709 1.57025432290749e-16 POLR2A essential 1.65706098852846e-13 2.38207580785066e-12 1 -0.725685196153453 -8.5196567251709 0.224901511015392 32.6025995160706 21.1955132342731 1.53818400883788 0.12458398446388 -14.3447499339769 49.1801607998738 -0.291677572839772 0.770644143709111 TMEM132C other 1 1 1 1.53818400883788 -0.291677572839772 3.27655563842491e-05 7.04070319743318 10.3391445211903 0.680975411747376 0.496177334863682 -61.758982467137 18.8300356155617 -3.27981230243121 0.00110535245176392 TMEM136 other 0.189319384788192 1 1 0.680975411747376 -3.27981230243121 4.03589413324823e-08 66.0220189251303 18.568701955311 3.55555380683175 0.000409861507351587 -104.167119027143 35.8919101442806 -2.90224506325814 0.00385431457798315 FRAT2 other 0.000300553036102995 1 1 3.55555380683175 -2.90224506325814 4.97439883209037e-36 53.4648827459003 8.64646513111399 6.18343819528155 1.2368935397033e-09 -134.335105918541 15.7596789787587 -8.52397476494293 1.54325762177161e-16 TMEM102 other 7.14671880206423e-32 2.34127613798972e-12 1.3719623142389e-05 6.18343819528155 -8.52397476494293 0.029014072536636 6.47384874059328 7.28086198793014 0.889159656003 0.374321427293482 45.5697911055246 17.1390151705459 2.65883369914032 0.00807867774986976 TMEM132E other 1 1 1 0.889159656003 2.65883369914032 6.20631447730202e-11 52.3521437549744 12.4563240700772 4.20285659400398 3.08954450230477e-05 -199.973146429445 47.6507763422828 -4.19663984051398 3.17274576813013e-05 ZNF322 other 5.41190622420736e-07 0.370481523344555 0.267863508349824 4.20285659400398 -4.19663984051398 0.342693177283291 1.90120737600532 7.15871357799585 0.265579472525506 0.790665020777942 -15.8713042689416 14.884858699565 -1.06627174562331 0.286779969027648 HEPHL1 other 1 1 1 0.265579472525506 -1.06627174562331 3.89342383663514e-14 821.036840417624 220.528071451513 3.72304911122457 0.000217576527817356 -1838.67625455428 397.6223445774 -4.62417738748676 4.71526991127843e-06 LRRC75A other 3.88875172803118e-10 0.0579978199087247 1 3.72304911122457 -4.62417738748676 0.000154721767943999 5.54617761834864 4.21352402459045 1.31628005108805 0.18865335439193 40.9209654252245 9.74245581570711 4.20027210790634 3.13125809939863e-05 CCL13 other 0.821108422478801 0.365762258590754 1 1.31628005108805 4.20027210790634 0.168037404835021 0.765704112668319 3.14375710636059 0.243563381890768 0.807660810868652 -12.2443529688927 7.04037975370599 -1.73916086876526 0.0825721329254729 CFAP65 other 1 1 1 0.243563381890768 -1.73916086876526 0.0010793508402227 147.782769221356 48.0446774238616 3.07594466537013 0.0022046502549552 -87.6859200961659 104.302519199361 -0.840688420272629 0.40089459808419 DDX60L other 1 1 1 3.07594466537013 -0.840688420272629 3.19475285085966e-08 71.5986983799274 15.5949190437263 4.59115550258216 5.48457762748317e-06 -203.031503108929 71.9394313558047 -2.82225615747165 0.00494378652422444 SYNE4 other 0.000239574516285966 1 0.0503758455084329 4.59115550258216 -2.82225615747165 8.84722233663373e-24 138.17887606399 18.4794019953543 7.47745387533255 3.21780783966095e-13 -331.275354359683 52.676647731521 -6.28884655014696 6.75778507837469e-10 OGFOD3 other 1.12235862562536e-19 9.50482471273399e-06 3.96112145062262e-09 7.47745387533255 -6.28884655014696 0.314491208138027 10.6187933113847 11.2101994375019 0.947243924658576 0.343951948912734 -18.0860459068923 25.5237475813372 -0.708596801831586 0.478890431619997 WASHC1 other 1 1 1 0.947243924658576 -0.708596801831586 1.37547649921045e-06 26.7981289114044 8.06390110376518 3.323221424292 0.000951185898870385 -77.9533352724186 22.6955352434257 -3.43474319668224 0.000639492442512573 AATK other 0.00907676941828973 1 1 3.323221424292 -3.43474319668224 0.00938859170378226 2.99057439339532 2.82403386037702 1.05897256947056 0.290083978294298 26.8835812589187 8.79721246978782 3.05592042379841 0.00235420324779746 DDN other 1 1 1 1.05897256947056 3.05592042379841 8.91529845604787e-13 68.1457478271271 23.035558021525 2.95828508966225 0.00323013685306516 -408.816459929952 71.690050202897 -5.70255507944157 1.95218866475121e-08 ZNF467 other 8.4365469289581e-09 0.000264287301434019 1 2.95828508966225 -5.70255507944157 0.0205905011911348 20.3063141795045 8.59565130518863 2.36239389646331 0.0185143465320658 -55.3583451673089 35.5491853996097 -1.55723245258713 0.120006631909724 SOX2 og 1 1 1 2.36239389646331 -1.55723245258713 9.59623810906527e-10 50.0122647908744 8.08281623944043 6.18748011947092 1.20764622320246e-09 -86.228434479264 50.6952090503843 -1.70091880661867 0.0895328808391172 ZNF678 other 7.86027863513536e-06 1 1.34024577851009e-05 6.18748011947092 -1.70091880661867 0.00205148571661792 225.354315715434 88.7837913988462 2.53823712825089 0.0114189966703367 865.696676547422 312.062187796188 2.77411589869651 0.00572533418158596 TMEM45A other 1 1 1 2.53823712825089 2.77411589869651 4.63323818714636e-15 219.489541080376 26.3125144647634 8.34164068106479 6.05311840932956e-16 125.310191128969 105.967289317982 1.18253653495791 0.237509465604855 RAP2B other 4.79215825696548e-11 1 7.87268580317403e-12 8.34164068106479 1.18253653495791 1.06834732386366e-06 112.090180479771 28.0331497764512 3.99848684053086 7.25381969162753e-05 -81.0067329710429 61.2004171917959 -1.32363040462904 0.186180767739682 ZBTB2 other 0.00710842129242637 1 0.606953882827252 3.99848684053086 -1.32363040462904 1.31992339432671e-55 158.610189462002 15.4851363194326 10.2427376931102 1.54540001256575e-22 -360.857768051584 38.4497597102484 -9.38517615639094 1.99387854424979e-19 RNF135 other 2.01459907676086e-51 3.06419254680307e-15 2.17236879766367e-18 10.2427376931102 -9.38517615639094 2.0912643776928e-37 40.3440912884236 10.8566063106068 3.71608678938718 0.000223665558820843 -292.77328764891 26.2980698122147 -11.1328812243446 4.95017219157762e-26 ACBD4 other 3.02564130164594e-33 7.7197935327653e-22 1 3.71608678938718 -11.1328812243446 3.5359736681745e-23 83.8891760490699 17.1435498339684 4.8933375445295 1.30873133489711e-06 -432.280276822298 50.8764981025355 -8.49665941926837 1.88502685528002e-16 SGSH other 4.4436581087949e-19 2.85826622066109e-12 0.0125127802929513 4.8933375445295 -8.49665941926837 1.08491522567553e-22 180.6002980977 62.0715422209255 2.90955068354684 0.00377505774930041 -845.645428201864 114.955075719305 -7.35631221945121 7.44987583034263e-13 SETD2 other 1.35310626946252e-18 1.0959512334017e-08 1 2.90955068354684 -7.35631221945121 0.112288613840473 46.1239077317683 24.1606696556458 1.90904922707679 0.0567864798799713 -51.6756788356414 127.884911203502 -0.404079561453581 0.68631449109851 C6orf223 other 1 1 1 1.90904922707679 -0.404079561453581 1.95954046428162e-07 56.1892006157448 26.8909709691823 2.08951921744064 0.0371454609670791 -173.683043167183 48.1605907149797 -3.60633124695377 0.000340440720401283 MEX3D other 0.00138774655680424 1 1 2.08951921744064 -3.60633124695377 4.63780175530298e-60 383.759226956837 21.8250024947743 17.5834677246302 1.48678163259013e-54 -248.338827811624 76.7437983541741 -3.23594652776418 0.00129035439977807 MRPS23 essential 7.12690995737409e-56 1 2.28875164520924e-50 17.5834677246302 -3.23594652776418 0.188712750253931 89.9712224762763 1508.57351151902 0.0596399325517004 0.952464559782405 7288.56918653954 4193.30909816354 1.73814260192066 0.0827578338563273 FDCSP other 1 1 1 0.0596399325517004 1.73814260192066 2.31446784630365e-08 1.49655284459257 1.82807413062755 0.81864997678121 0.413344607237718 -20.6064352382628 3.91885960813528 -5.25827340063045 2.09323221613737e-07 GPR135 other 0.000175182071286723 0.00272957480984313 1 0.81864997678121 -5.25827340063045 0.0109495717262718 -12.0301050399296 4.08108423984067 -2.94777180105433 0.00333735953019805 -12.1736694841208 19.1138325790145 -0.636903636871162 0.524454064232647 P2RY13 other 1 1 1 -2.94777180105433 -0.636903636871162 0.238695497420238 32.4148906781759 19.9783942740473 1.62249729550508 0.105278396815711 42.5844630958391 44.1096312548367 0.965423239423922 0.334763421629387 TNFSF15 other 1 1 1 1.62249729550508 0.965423239423922 1.75565535142005e-34 71.630206163627 5.49530410646117 13.0348029473759 8.97974368878596e-34 -74.1591242446268 38.9167573363258 -1.90558333531568 0.0572597645764025 ZFP41 other 2.4956640820436e-30 1 1.33708383526023e-29 13.0348029473759 -1.90558333531568 0.000519889648684566 77.8270439124204 19.9222957790823 3.90652988869566 0.000105444204678554 62.4896224661001 39.6387143844769 1.57647954623301 0.115497717444972 PHLDA2 other 1 1 0.869176579165319 3.90652988869566 1.57647954623301 2.34045260670171e-05 33.2266435117319 9.45617432223283 3.51375116188492 0.000478604947943371 -50.829692858772 29.421331408787 -1.72764760889071 0.0846189666796675 ATG9B other 0.137197331804854 1 1 3.51375116188492 -1.72764760889071 0.358632051792191 1.5907130523543 10.3254231052959 0.154057905049762 0.877622065696274 -24.4423737242974 19.6920806021986 -1.24122860443546 0.215064244340374 GPR88 other 1 1 1 0.154057905049762 -1.24122860443546 7.34080707402035e-14 85.9891274442876 22.245467732948 3.86546727075234 0.000124396012448441 -572.491911453229 96.6294670974752 -5.92461004546083 5.58527582565356e-09 HKR1 other 7.26005819620613e-10 7.68757364642956e-05 1 3.86546727075234 -5.92461004546083 0.53839531414546 1.57882449309041 2.37112431525311 0.665854794256907 0.505803788771872 18.0638877428965 18.6548677414914 0.968320332967008 0.333341594790599 PLAG1 other 1 1 1 0.665854794256907 0.968320332967008 0.0154308261403328 -74.5134123999615 67.3200119115784 -1.10685382079004 0.268849951406618 -619.399670020036 218.732315038377 -2.83177028465758 0.00480181279701834 ZBTB20 other 1 1 1 -1.10685382079004 -2.83177028465758 0.00463828048725055 131.923567127276 40.885923815465 3.22662556733953 0.00132807931603749 153.744937682174 145.432818694775 1.05715435526863 0.290911227994876 C3orf58 other 1 1 1 3.22662556733953 1.05715435526863 1.92372670577273e-16 85.137020634552 51.1018273139535 1.66602693307809 0.0962826609861289 -827.43209548168 113.761424372493 -7.27339781517143 1.22631160838537e-12 C5orf30 other 2.07877907825801e-12 1.79998017878804e-08 1 1.66602693307809 -7.27339781517143 2.5838105410448e-10 59.8469460182555 14.446526627078 4.14265294095543 3.98524197500963e-05 -104.365915751612 32.6574106856665 -3.19578048474673 0.00147619616095521 AMIGO1 other 2.1859037177239e-06 1 0.341575089678076 4.14265294095543 -3.19578048474673 0.0257548315395444 5.19748137197506 2.29181841034282 2.26784170531102 0.0237345366519062 -0.284723582268104 3.58713159927814 -0.0793736093555643 0.936764973337779 GPR3 other 1 1 1 2.26784170531102 -0.0793736093555643 0.00457709680277193 177.355629895293 140.040843533707 1.26645645241779 0.205891711597215 -1791.27535589808 606.404303920567 -2.95392915966626 0.00327327994348564 SIAH2 other 1 1 1 1.26645645241779 -2.95392915966626 2.31885711618049e-18 1104.63705429789 136.554050206895 8.08937598426586 3.99207567837969e-15 -1362.32438221508 439.43038033294 -3.10020527297839 0.00203492232018392 COPG1 essential 2.64210579817605e-14 1 5.1150465667079e-11 8.08937598426586 -3.10020527297839 0.264884481350493 4.64090759885017 5.33643938020317 0.869663696746328 0.384877895533976 57.7941162164912 39.2362733141333 1.47297669566577 0.141350931792279 ADGRB1 other 1 1 1 0.869663696746328 1.47297669566577 0.58501174945815 -5.39731970773789 6.27363456339974 -0.860317835410074 0.389993550872335 10.4365086857811 22.3205564975487 0.467573856723837 0.640276952699908 SLC9A9 other 1 1 1 -0.860317835410074 0.467573856723837 8.49490156669277e-07 95.2871458629237 24.1482999161589 3.94591528984457 8.99734074666672e-05 -92.4045067260629 48.6592034879636 -1.89901396040978 0.0580943528811227 LSM10 essential 0.00571367079375756 1 0.746329414936005 3.94591528984457 -1.89901396040978 3.71712566463643e-08 2.61855080767671 18.4242154438876 0.142125498676007 0.887033497558683 -176.052032756801 35.0239139514622 -5.02662360925116 6.78545684576228e-07 RELL1 other 0.000277669287148341 0.00868199203415283 1 0.142125498676007 -5.02662360925116 6.13557561349126e-13 20.9460012120365 26.7775814115227 0.782221549068774 0.434428514178824 -333.309314775669 49.6596936806329 -6.71186811822117 4.88616496652625e-11 RFX7 other 5.83984086892098e-09 7.01946459091161e-07 1 0.782221549068774 -6.71186811822117 1.75437170955604e-05 107.987965670298 30.8485294470822 3.50058714648104 0.000502759398539304 -161.809077905113 89.5278676177999 -1.80735990044894 0.0712646248736103 SLC35C1 other 0.104367573001489 1 1 3.50058714648104 -1.80735990044894 0.0887739596479983 9.18274998246899 9.2791393889726 0.989612247163981 0.322806892999137 63.8218175231841 30.2813981339297 2.10762453044309 0.0355238090493826 TIGIT other 1 1 1 0.989612247163981 2.10762453044309 3.46651695170713e-14 132.951811395854 22.2552215290477 5.9739603680118 4.21811384311456e-09 -246.156878046921 65.6663607648053 -3.74859936168189 0.000197112857698519 RNF41 other 3.47137007543952e-10 1 4.57791895393223e-05 5.9739603680118 -3.74859936168189 0.710311939232221 16.6998823089995 27.2217942096167 0.61347471002113 0.539820814715957 37.8635341107969 49.658384165699 0.762480188329421 0.446106385315138 SLC2A4 other 1 1 1 0.61347471002113 0.762480188329421 3.29571157629713e-09 42.2141845317066 6.63053605392449 6.36663222828278 4.30009915953359e-10 32.9694273493925 40.4657460647591 0.81474902987406 0.415594783911605 IBA57 other 2.62536384167829e-05 1 4.8578220205251e-06 6.36663222828278 0.81474902987406 7.31232729832793e-22 733.225821830658 120.841239874107 6.06767873777642 2.44391429431777e-09 -1103.85075728426 220.440308471947 -5.00748145806887 7.47929483616488e-07 CLDN7 other 8.98831271510469e-18 0.00955704294165148 2.67657493513682e-05 6.06767873777642 -5.00748145806887 4.37265765010687e-08 67.5754853483946 12.4671742662955 5.42027278234832 9.12127110506211e-08 -70.5462028217563 54.6379000629649 -1.29115875135133 0.197222314775874 ZNF329 other 0.00032445119763793 1 0.000934200586580461 5.42027278234832 -1.29115875135133 3.8524683562169e-06 69.9984198363534 15.1113941373088 4.63216161264255 4.55125822679422e-06 -26.7681893305834 50.8188024091261 -0.526737901359446 0.598594337944546 ZNF101 other 0.024351452479647 1 0.0419899084004035 4.63216161264255 -0.526737901359446 4.37110697589321e-15 117.385656785307 40.5271203432314 2.89647169083683 0.00392539993432345 -582.271121119308 93.607943554692 -6.22031741119392 9.88975257572501e-10 C5orf24 other 4.52365860935188e-11 1.38555433585907e-05 1 2.89647169083683 -6.22031741119392 1.23460708754171e-19 110.163144451255 15.6904925979849 7.02101248659351 6.74967241418185e-12 -162.228012808024 39.9489331024682 -4.06088473982302 5.62427443940755e-05 ADO other 1.45189793494905e-15 0.646266033734811 8.04290964873909e-08 7.02101248659351 -4.06088473982302 1.07126981196326e-75 357.220259812271 17.6497741126717 20.239367231097 1.75349706379479e-67 -115.268472533196 62.8664459771443 -1.83354523612012 0.0672973538950156 COA4 other 1.66239649420459e-71 1 2.71862184770745e-63 20.239367231097 -1.83354523612012 9.76652705676962e-37 217.121392385938 24.5072567798632 8.85947351579307 1.15074528946284e-17 -618.399637414408 76.343116125145 -8.10026717275595 3.65014030087817e-15 PRKAG1 other 1.40725888360993e-32 5.48871597043051e-11 1.53923689918549e-13 8.85947351579307 -8.10026717275595 3.23626746789717e-31 71.0260883171034 9.01479500553387 7.87883565555322 1.80948052234949e-14 -62.6435494626123 19.5987568371619 -3.1963021931999 0.00147281756237528 GINS3 essential 4.47996505581005e-27 1 2.29062139324222e-10 7.87883565555322 -3.1963021931999 2.2722836579224e-19 -8.3423641474074 25.741523562506 -0.324081988665135 0.746001217760198 -397.082668920157 46.8426326608913 -8.47695029856167 2.20618214758829e-16 CCDC149 other 2.65629959611129e-15 3.34346904467005e-12 1 -0.324081988665135 -8.47695029856167 1.04728365443965e-23 171.101518730807 17.194201514763 9.9511174499088 1.53737194109473e-21 -48.8813122916929 40.9456748513395 -1.19380893022682 0.233074957476018 MRPS11 essential 1.32711784690593e-19 1 2.14340396027427e-17 9.9511174499088 -1.19380893022682 1.45287041826988e-26 156.920265152182 13.6012288367081 11.5372123383935 1.12938513140582e-27 -12.6137046300472 113.877970435295 -0.110765098656323 0.911843853266591 SNRPE essential 1.91735309099076e-22 1 1.64178716552464e-23 11.5372123383935 -0.110765098656323 2.61988482781468e-09 77.5448663581593 12.4776901668201 6.21468118869962 1.04054621544751e-09 18.1868752586573 31.7702388868365 0.572450063200273 0.567259393391679 RTKN2 other 2.09800377011399e-05 1 1.15802388317153e-05 6.21468118869962 0.572450063200273 8.61768669565915e-09 -139.717167747364 86.5626578049414 -1.61405820119571 0.107097875845625 -1037.20767682004 168.475734356271 -6.15642175879575 1.45095389990539e-09 CHST15 other 6.69163371917933e-05 2.02538654887793e-05 1 -1.61405820119571 -6.15642175879575 1.28273069949559e-58 1430.55243563223 77.3123740796819 18.5035377927708 1.11464761182725e-59 617.272591279597 482.670099295111 1.27887058299459 0.201486906343339 IDH2 other 1.96706752767648e-54 1 1.72190763075074e-55 18.5035377927708 1.27887058299459 2.57814305234016e-14 133.218057912431 89.3529809886564 1.49091900951064 0.136581048279789 -1005.95066678678 160.465135912926 -6.26896715640859 7.57018361783909e-10 TMEM259 other 2.59232283912803e-10 1.06345939463403e-05 1 1.49091900951064 -6.26896715640859 5.13422104062623e-17 106.978876827161 18.2595266805383 5.85879791403262 8.13627094596419e-09 -303.736206875991 54.7086381085344 -5.55188755153109 4.44814475683949e-08 WRB essential 5.6414820794401e-13 0.000595651064388376 8.73672774177635e-05 5.85879791403262 -5.55188755153109 2.32130754057719e-08 139.559167360802 121.184488282515 1.15162566875267 0.249986443375694 -2325.7190218887 428.754794737931 -5.42435688284315 8.80343830999013e-08 TNRC18 other 0.000175676554670882 0.00116751198867089 1 1.15162566875267 -5.42435688284315 0.0676251429720507 32.1937987787315 16.224565317915 1.98426263803711 0.0477589784281569 -4.22256981270329 37.3023537489983 -0.11319848182011 0.909917482916971 FAM181B other 1 1 1 1.98426263803711 -0.11319848182011 8.56152978623735e-26 46.4303880797058 53.541611302568 0.867183242157655 0.386227504093341 -1135.97451650877 112.307297462707 -10.1148771466607 3.87788253198042e-22 TMEM30B other 1.11890632776336e-21 6.00877898330366e-18 1 0.867183242157655 -10.1148771466607 8.43109265928748e-25 134.952191677387 13.1395389132297 10.2706946239574 9.95900719502612e-23 -66.4213831738248 68.3639468354967 -0.971584969101531 0.331691249248688 DEXI other 1.08676784378216e-20 1 1.40272616341943e-18 10.2706946239574 -0.971584969101531 1.62017756772151e-11 190.538164636516 37.2201205562247 5.11922481144814 4.27579586754061e-07 -127.13394827795 68.0503052843441 -1.8682347969892 0.0622716641657263 NOP10 essential 1.45216515394879e-07 1 0.00421465198663478 5.11922481144814 -1.8682347969892 1.21098231638904e-25 139.085509908972 12.3863456910462 11.2289381693516 1.81644438045996e-26 78.5398663163125 156.141886528812 0.50300318551499 0.615164870356161 TDRKH other 1.5787576458764e-21 1 2.62476212976464e-22 11.2289381693516 0.50300318551499 8.34881161207183e-06 26.6456528781166 6.74781572944502 3.94878193870124 8.88730900407605e-05 -33.5745263525071 22.5181558981176 -1.49099804195395 0.136541612765898 ZNF708 other 0.0510780294426555 1 0.737557774248271 3.94878193870124 -1.49099804195395 3.32623082255976e-86 547.588654004736 44.536426384243 12.2952984435786 8.09276099067425e-31 -962.519917449053 100.262575632925 -9.59999193490671 2.93050174091932e-20 IST1 other 5.1816023753836e-82 4.51678233327895e-16 1.19360131851455e-26 12.2952984435786 -9.59999193490671 4.30949584790441e-08 38.7632784033566 12.7506676012995 3.04009794745227 0.00247925185387051 -100.453590412558 26.5794721920967 -3.77936738873345 0.000174668839581182 ERCC6L2 other 0.000319980066706902 1 1 3.04009794745227 -3.77936738873345 0.00508973644368321 101.818744557839 57.4322507350546 1.77284963160415 0.0768685397279684 -272.545927434346 133.885739945843 -2.03566061288224 0.0423164632139729 MRPL41 essential 1 1 1 1.77284963160415 -2.03566061288224 8.16213872510913e-05 629.809623614598 154.572568260725 4.07452389968876 5.29641916635693e-05 -42.0559601444204 468.572049449135 -0.0897534545516798 0.928516110569931 CREB3L2 og 0.449080872655504 1 0.448977452732077 4.07452389968876 -0.0897534545516798 4.0794812499022e-06 39.2466575337883 23.7375302052171 1.6533589296987 0.0988368821276015 -321.596860127892 76.9838181719887 -4.17746050747205 3.43537045559812e-05 TP53TG1 other 0.0256884934306341 0.400151950668069 1 1.6533589296987 -4.17746050747205 0.0218807153806098 87.9340500932861 61.6349757455629 1.42669075520187 0.154246962066185 -235.35097482227 139.459839282931 -1.68758960308852 0.0920674876824839 UNC5C other 1 1 1 1.42669075520187 -1.68758960308852 1.48862317241045e-38 219.40595239307 16.9874748553993 12.915748471194 2.03897493438754e-33 -206.432391547079 58.1251705610513 -3.55151459435726 0.000416755383346564 TSEN54 essential 2.16579785353997e-34 1 3.03297521490146e-29 12.915748471194 -3.55151459435726 3.09162042614921e-17 125.722191338244 33.5640330459526 3.74574149555024 0.000199312393421713 834.437530419772 94.2385611498753 8.85452324651581 1.22357597736644e-17 RGMA other 3.42025967744887e-13 1.86791108704761e-13 1 3.74574149555024 8.85452324651581 1.9727029501219e-42 576.265603445278 45.0178505989318 12.8008244680378 6.14466957178864e-33 -443.46307713709 119.488513998145 -3.71134481715938 0.000227623769987915 MRPS16 essential 2.91920582559038e-38 1 9.12544878106332e-29 12.8008244680378 -3.71134481715938 0.00366737690369916 -2.65852807924001 0.975111359753407 -2.72638407157139 0.00661051274168622 -5.65068343842192 2.02660325932039 -2.78825340501862 0.00548543875395042 FAM159A other 1 1 1 -2.72638407157139 -2.78825340501862 0.0498934247760501 38.4574711397598 17.2906215696076 2.22418095179169 0.0265544177256201 64.2957064793378 33.2044202078828 1.93635986042828 0.0533519216209176 RAD51B other 1 1 1 2.22418095179169 1.93635986042828 3.87385679394082e-06 239.137600981304 108.37233546503 2.20662957898946 0.0277737069456375 -855.878488945959 233.298163141896 -3.66860363330594 0.000268864645349252 ARL6IP4 other 0.0244711533673242 1 1 2.20662957898946 -3.66860363330594 1.26062296738666e-12 125.053668176014 16.8748065086194 7.41067271569237 5.09631368605923e-13 334.089465754159 201.820299808791 1.6553808812626 0.0984482918347852 EXT1 ts 1.18712864838802e-08 1 6.23584942626208e-09 7.41067271569237 1.6553808812626 2.99978736467391e-09 375.950700988202 73.5404872859372 5.11215950373629 4.4861307948523e-07 1070.75325516297 217.311575737163 4.92727205870544 1.12318704835061e-06 SHMT2 other 2.39383031700978e-05 0.0142307799026022 0.00441524992829364 5.11215950373629 4.92727205870544 5.01001582921567e-12 54.9934556243384 23.9309176347027 2.29800864571074 0.0219398036690209 -237.832971439927 47.5380285575793 -5.00300451357291 7.63070094715078e-07 MOB2 other 4.60670955496381e-08 0.00974593124970097 1 2.29800864571074 -5.00300451357291 0.0473901552943425 14.8423396709258 7.46809686506543 1.98743266713048 0.0473763673181062 32.5516793850398 15.3443028165357 2.12141794738049 0.0343390107763566 HHIPL1 other 1 1 1 1.98743266713048 2.12141794738049 3.05120738995562e-70 80.5795605828976 27.3310005753301 2.94828432500314 0.00333242495694929 -846.494557500542 49.232885301237 -17.1936816686889 2.97349764476797e-53 CYB5D1 other 4.72265879817331e-66 4.66303900652512e-49 1 2.94828432500314 -17.1936816686889 8.08297746692639e-06 568.866129041426 116.482736521294 4.88369475194662 1.37157738520003e-06 249.644562280359 342.686092999643 0.728493415344459 0.466625648620055 BACE2 other 0.049524402939858 1 0.0130930777191195 4.88369475194662 0.728493415344459 6.42262959617959e-05 94.3232754869586 22.6074116561373 4.17222798087778 3.51858794525532e-05 136.260441667934 48.3279108468133 2.81949786945775 0.00498783267237116 UBE2E2 other 0.358190052578936 1 0.303161537363199 4.17222798087778 2.81949786945775 2.82605197905936e-05 1387.13235371169 309.148977497686 4.48693819057535 8.84115382151973e-06 1932.94533053001 897.018323365531 2.15485601595938 0.0316161855543471 SYNM other 0.164334922582302 1 0.0800478067000396 4.48693819057535 2.15485601595938 0.179909995043196 4.09667987923492 5.15471640264572 0.794743989627101 0.427111585972455 17.6315129082234 9.510916675036 1.85381846047523 0.0643102560029702 GABRG3 other 1 1 1 0.794743989627101 1.85381846047523 7.77310316860423e-16 4.31073014188993 1.29410784933298 3.33104396523969 0.000924033780489158 -13.2093330385645 2.51589401385016 -5.25035353868101 2.1821268939419e-07 PRR34 other 8.24881708252281e-12 0.00284396598087448 1 3.33104396523969 -5.25035353868101 0.29027145625835 7.75484968733632 15.3790649058165 0.50424715253028 0.614292625281968 59.2984353949153 37.6746444166078 1.57396138206882 0.116079890524883 FIGN other 1 1 1 0.50424715253028 1.57396138206882 2.99987528281021e-11 141.861047540405 52.3708504075697 2.70877876598124 0.00696905975397428 -450.320612294227 107.426090998175 -4.19191099769123 3.23559818176791e-05 B4GALNT4 other 2.65668955045672e-07 0.377626663794133 1 2.70877876598124 -4.19191099769123 2.40749940332743e-57 498.799502144534 26.9678131038221 18.4961049761147 5.56952845781909e-58 88.6949879387078 184.724196312434 0.480148186914796 0.63134213295026 C8orf33 other 3.68612233643463e-53 1 8.59879498602689e-54 18.4961049761147 0.480148186914796 5.63783399910983e-05 14.1312547287762 3.32085361317112 4.2553079343001 2.45621406101939e-05 -7.58270059401491 13.5333325890689 -0.56029810426292 0.575505515960872 SPACA6 other 0.316564379050017 1 0.214476611808213 4.2553079343001 -0.56029810426292 1.85558518729376e-28 33.497879977261 3.08571616623734 10.8557878212459 7.2206681056408e-25 -32.1394448353409 11.5807160857015 -2.77525539850017 0.00571597797762738 ZSCAN22 other 2.50132883247199e-24 1 1.03349422596037e-20 10.8557878212459 -2.77525539850017 0.000231985954703193 7.14771739869412 2.56842838991827 2.78291480765075 0.00557415582193829 -15.8037013300876 7.81506943428592 -2.02220869091122 0.0436427774213967 KCNJ14 other 1 1 1 2.78291480765075 -2.02220869091122 3.28811388229758e-25 183.396475699375 16.5273450460059 11.0965478840593 1.03078282616298e-25 -39.8013663641137 112.910987417153 -0.352502154790892 0.724611136359906 FBXL6 other 4.25975153451652e-21 1 1.4824718605876e-21 11.0965478840593 -0.352502154790892 0.97476442420177 64.0004210230138 295.070710985991 0.216898589525046 0.828368694344076 123.589563636926 1084.80317826118 0.113928098768135 0.909336824269935 C1S other 1 1 1 0.216898589525046 0.113928098768135 2.63365716806769e-48 7.54595421926896 4.15377336338288 1.81665044265281 0.0698218441811148 -100.757601687452 8.15683300117861 -12.3525394810575 4.58142927946804e-31 KBTBD3 other 3.96418076937549e-44 7.17222753700722e-27 1 1.81665044265281 -12.3525394810575 0.00130773497600545 4.76256457093347 6.77735604862314 0.702717185988925 0.482535957283085 -78.0757629754796 22.9875066231771 -3.39644330528479 0.000733134768550895 YBEY other 1 1 1 0.702717185988925 -3.39644330528479 0.798160721133217 1.02856915978872 33.2929269373432 0.0308945248858554 0.975365555987029 64.8425511083756 98.3652153773778 0.659202044743229 0.510058968642834 NXPH4 other 1 1 1 0.0308945248858554 0.659202044743229 7.98126280020586e-05 32.9653807899214 10.5717672055274 3.11824694481406 0.00191775632518481 -46.352247254099 25.246421510014 -1.83599276577528 0.0669166202976408 CACNB4 other 0.439528142407337 1 1 3.11824694481406 -1.83599276577528 2.23980662279727e-31 78.3451316036816 13.9342677112898 5.62247928825172 3.04291204152283e-08 -285.15160536918 31.4885509842706 -9.05572331707551 2.56668875825229e-18 TRAPPC6B other 3.10571586317069e-27 3.93011382663591e-14 0.00031923190227616 5.62247928825172 -9.05572331707551 2.67052694393505e-23 19.1524234503467 3.04823282868873 6.2831235429564 6.82962242440471e-10 -24.7726291725595 5.61348694657407 -4.41305545168825 1.23067766819855e-05 PGBD4 other 3.36139226433105e-19 0.1477674676206 7.65054303981815e-06 6.2831235429564 -4.41305545168825 3.45092713438651e-44 777.02042222664 49.9826740669705 15.5457953527162 3.35795107071101e-45 223.345978016995 140.435008038851 1.590386764212 0.112341686056941 NPLOC4 essential 5.13843050310151e-40 1 5.1161742513353e-41 15.5457953527162 1.590386764212 0.112457677227645 -26.0830779459997 21.3656353771439 -1.2207958006202 0.222715544303877 -296.238734448117 163.724464582092 -1.80937366449338 0.0709691691236979 TSHZ2 other 1 1 1 -1.2207958006202 -1.80937366449338 4.50040764414657e-43 788.413858676512 51.6348587771514 15.2690232402725 4.44395821148032e-44 565.619816158622 278.025603847347 2.03441628516049 0.042393248662521 CAPN12 other 6.67590469932702e-39 1 6.75837164801927e-40 15.2690232402725 2.03441628516049 5.71646724092712e-60 738.939461783891 43.790009257873 16.8746130523148 1.17413962733827e-51 -730.198623182462 153.410541677961 -4.75976823493196 2.48984602908626e-06 EXOC7 essential 8.78335191568452e-56 0.0310608292128511 1.80242174192698e-47 16.8746130523148 -4.75976823493196 1.64809845205079e-48 1040.19136108772 64.5128692500062 16.123780777083 8.97775882944019e-48 2100.85614059612 344.668548774384 6.0952940094668 2.12208924052188e-09 KPNA2 other 2.48154183925287e-44 2.95140171571784e-05 1.37189132672676e-43 16.123780777083 6.0952940094668 0.393275514537024 -3.33411758229071 3.29724529636406 -1.01118275487945 0.312397441604086 8.75450917663029 12.6201507634653 0.693692915458203 0.488183372386047 NCF1B other 1 1 1 -1.01118275487945 0.693692915458203 8.32558279521234e-09 68.6686691401719 14.7852023379522 4.64441862685275 4.29552323069755e-06 -182.804207525874 51.9217393522282 -3.52076432350931 0.000466953276393469 CEP97 other 6.47230806499807e-05 1 0.0396906346516453 4.64441862685275 -3.52076432350931 0.0326949304136391 33.601267331114 13.1473058039729 2.55575308219881 0.0108716475638458 40.4298376470023 33.196331495221 1.2179007687287 0.223799541713015 FES other 1 1 1 2.55575308219881 1.2179007687287 1.66855315425705e-24 172.427928935995 26.5677919277796 6.49011138767999 1.93013676219998e-10 -310.965572848691 54.9613609073777 -5.65789434094869 2.47800600965271e-08 GLRX5 essential 2.14058684159637e-20 0.000334530811303115 2.2034441277275e-06 6.49011138767999 -5.65789434094869 0.00280984160508773 168.871465036429 49.8678720443045 3.38637800478829 0.00075968004042688 17.0840744474077 155.541839426169 0.109835877667609 0.912580266857858 MXRA7 other 1 1 1 3.38637800478829 0.109835877667609 1.22795980449653e-26 597.685306171693 71.9989472043383 8.30130619098385 8.24454995084313e-16 -478.725693712413 148.494913571547 -3.22385246873628 0.00134090270711556 LIMK2 other 1.62176651379857e-22 1 1.06923568312484e-11 8.30130619098385 -3.22385246873628 2.11467672887217e-21 121.074774904281 22.6021720019353 5.3567761051422 1.25599230187164e-07 -446.71708722068 64.9398166400498 -6.87893976813572 1.67459293735807e-11 MFSD5 other 2.57419598205609e-17 2.42313598035712e-07 0.00127483218639971 5.3567761051422 -6.87893976813572 3.25792571260988e-09 325.376458275774 53.4944161579378 6.08243778780811 2.23226907127636e-09 -82.3310508351184 163.664568431106 -0.503047492956764 0.615134485577338 ADI1 other 2.59591520780755e-05 1 2.44857594428304e-05 6.08243778780811 -0.503047492956764 4.82739972686844e-23 81.1342103299776 11.0694559999462 7.32955714629266 8.40285844307945e-13 -88.5040860489149 23.1790915217525 -3.81827242736661 0.000149851199729197 RWDD4 other 6.05307651752033e-19 1 1.02237578676948e-08 7.32955714629266 -3.81827242736661 0.00123364473867857 -0.855208967176792 1.22713833070184 -0.696913254015683 0.486152604876467 -8.19056012478322 2.28718900147287 -3.58105959739609 0.000372624271345726 SPNS3 other 1 1 1 -0.696913254015683 -3.58105959739609 0.654491371175498 87.2634136999233 95.1287287913561 0.91731924528621 0.359388706382272 42.0891739828056 226.567643968364 0.185768688086294 0.852696570553396 SATB1 other 1 1 1 0.91731924528621 0.185768688086294 8.17963864980182e-07 0.264640851242504 16.7485590615184 0.0158008130890821 0.987399371902726 -390.30873810425 74.3962171572511 -5.24635193855698 2.26401474470495e-07 NXPH3 other 0.00550735070291156 0.00294865280350373 1 0.0158008130890821 -5.24635193855698 0.88086507116562 -2.37432696484027 73.1767825129173 -0.0324464520481089 0.974127941319061 80.0919318791525 173.607554586944 0.461338978420101 0.644740165978291 CSF1R other 1 1 1 -0.0324464520481089 0.461338978420101 3.67350811062781e-08 763.529490234778 132.208887699206 5.77517520585995 1.30475785744208e-08 754.46588974015 562.719863527926 1.34074863647089 0.180571070934397 EPHB3 other 0.000274594731269429 1 0.000139061092446177 5.77517520585995 1.34074863647089 0.00132221243267671 10.3822560021746 3.47212801693313 2.99017085532033 0.00291951970280614 -32.0374569516343 19.8351678889387 -1.6151845616341 0.106873801961805 ACTL10 other 1 1 1 2.99017085532033 -1.6151845616341 0.000442698066197955 108.611019794853 40.5525895299373 2.67827581552277 0.0076227377716285 290.12573113284 80.7330861690461 3.59364103244299 0.000355528633702103 C2orf82 other 1 1 1 2.67827581552277 3.59364103244299 0.0661842275446194 -7.99662011475764 3.68424379193408 -2.17049157611792 0.0304022685807828 -28.3566383406164 20.7977777620644 -1.36344558851569 0.17330713122264 HS3ST4 other 1 1 1 -2.17049157611792 -1.36344558851569 3.57873151277684e-20 92.9999997654334 67.2595065963514 1.38270416290087 0.167322915666139 -1060.02949526593 130.933241228415 -8.09595397868972 3.74317336889388e-15 TRAK1 other 4.25153303717888e-16 5.62711252545817e-11 1 1.38270416290087 -8.09595397868972 2.65489986330907e-05 10.7102377608035 4.37340108318689 2.448949354766 0.0146489650399043 -42.3490061965109 12.2878302879824 -3.44641854615527 0.000612983252022376 TSPAN10 other 0.154886858025451 1 1 2.448949354766 -3.44641854615527 0.00505999470393319 90.0541422945361 30.7843896345084 2.92531842806421 0.00358625023705322 -78.329272839513 120.467465146766 -0.650211015431296 0.515833474952868 PLCB1 other 1 1 1 2.92531842806421 -0.650211015431296 7.4313443187805e-28 239.566676982049 20.1461531416089 11.8914353176071 6.21099350256271e-29 142.570841889117 78.6037890919738 1.81379095761269 0.0703009541249796 SKA2 other 9.95577198387023e-24 1 9.08668349424924e-25 11.8914353176071 1.81379095761269 0.333545149088321 -15.2130833715755 22.8367361224947 -0.666167147966048 0.505594118338134 -66.9155710102963 45.1102361707627 -1.48337886676076 0.138568178550897 NDN other 1 1 1 -0.666167147966048 -1.48337886676076 0.206755012750642 -21.0033119188563 22.6196427706727 -0.928543042513826 0.353543126041683 -72.4165022682013 40.8627379699624 -1.77218918422533 0.0769301041314769 NTM other 1 1 1 -0.928543042513826 -1.77218918422533 3.30922979404872e-10 812.888990934565 188.653946298212 4.30888940774979 1.95110345683102e-05 -2401.79158405773 577.662488609097 -4.15777661076937 3.73913247392523e-05 TTC3 other 2.78074579593914e-06 0.434636758769069 0.171662821861122 4.30888940774979 -4.15777661076937 5.02243294318842e-07 24.1394510906428 4.66676022364228 5.17263581881707 3.2560892390519e-07 0.513389976588585 21.4448773347663 0.0239399819627916 0.980909309768677 BRICD5 other 0.00343885983620111 1 0.0032313429608351 5.17263581881707 0.0239399819627916 1.57672133503651e-19 23.6793211340576 9.18521431815191 2.57798243066167 0.0102002986891128 -171.670789336917 21.8818336678951 -7.84535665257301 2.30703856700593e-14 IGIP other 1.84917878173082e-15 3.44371646896975e-10 1 2.57798243066167 -7.84535665257301 0.000723032329157111 281.195821672378 89.020341826572 3.1587816436405 0.00167918264093906 -726.154618569876 524.204131643972 -1.38525161236818 0.166587105476751 TSKU other 1 1 1 3.1587816436405 -1.38525161236818 9.08451060913923e-08 2419.44377612404 418.681059310097 5.77872755961494 1.27070197460943e-08 1714.29540628854 859.290399245113 1.99501287084617 0.046541704525074 ANXA2 other 0.000658717864268685 1 0.000135494951552604 5.77872755961494 1.99501287084617 0.137965559881248 6.38014942959318 4.14297235285926 1.53999324306133 0.124144518943109 14.7302239094992 8.13014229820086 1.8118039474855 0.070568793605987 RGS6 other 1 1 1 1.53999324306133 1.8118039474855 0.000290462675480186 4.00738444378635 9.09113730451192 0.440801223164618 0.659538016130033 -136.043711369536 35.5675563230685 -3.82493838299768 0.000146496699610755 HOXB4 other 1 1 1 0.440801223164618 -3.82493838299768 5.43821940695084e-07 62.3871736285333 16.8188431833239 3.70936175267933 0.000229082409217571 -49.6291884221916 29.5656790030848 -1.67860810560155 0.0938016736955962 PAQR7 other 0.00371212856718464 1 1 3.70936175267933 -1.67860810560155 0.60902202985426 -0.823944667476092 8.93384462358912 -0.0922273334931895 0.926551562323501 17.9520762564373 19.575372817367 0.91707455198557 0.359512207088484 PAPPA other 1 1 1 -0.0922273334931895 0.91707455198557 8.65267142258378e-62 516.670499248167 29.2654756025842 17.654607984657 1.83986105051777e-55 -930.931447520785 182.251765717561 -5.10794199362364 4.51590800141746e-07 NGRN other 1.33199223879255e-57 0.00582100541382711 2.83375399000747e-51 17.654607984657 -5.10794199362364 0.00102874308471204 -11.8094594940108 3.95943551741412 -2.98261190062857 0.00298708960217554 -26.9459696423472 8.78163680276343 -3.06844501173947 0.00225975801278069 GRID1 other 1 1 1 -2.98261190062857 -3.06844501173947 0.00067402965405359 1517.92556056426 410.575313432914 3.69706972363374 0.000240685807617541 62.5029144893776 881.016825523049 0.0709440644930593 0.943468883863358 RPS17 essential 1 1 1 3.69706972363374 0.0709440644930593 0.0959605000162723 23.0646814635386 10.8872445023607 2.11850495858135 0.0345866770739657 4.19644032542588 24.1479516526398 0.173780384597015 0.862102945390023 HCAR2 other 1 1 1 2.11850495858135 0.173780384597015 9.64105686160279e-11 15.33885708484 2.57615147871127 5.954175137447 4.86386845138165e-09 -16.6617802110261 9.05240184510749 -1.84059219819447 0.0662609640881935 CCDC87 other 8.31733975450472e-07 1 5.26854230653661e-05 5.954175137447 -1.84059219819447 0.074613995965296 115.70989812504 52.8705855347054 2.18854958678462 0.0290611985679916 273.86727063296 413.743398109276 0.661925415328628 0.50830402482646 C1orf116 other 1 1 1 2.18854958678462 0.661925415328628 1.97350519958547e-05 12.7045915328055 16.0839603967007 0.78989199298275 0.429933751455811 -200.237401929444 47.1672671985586 -4.24526189076232 2.56593529280827e-05 TMEM198B other 0.116870977919451 0.301600034316684 1 0.78989199298275 -4.24526189076232 1.45971202147518e-08 377.177237240099 289.959989960434 1.30079062732608 0.193907374460884 -3191.58879677306 639.790657030038 -4.9884892217537 8.31471422648522e-07 CRIP2 other 0.000111770149484354 0.0105987662245007 1 1.30079062732608 -4.9884892217537 1.37920714345139e-42 73.0968904888126 8.66262264742806 8.4381940047354 3.01541993277717e-16 -101.613007281724 19.3587354922867 -5.24894858562485 2.20811305227194e-07 DDX28 other 2.0413644930224e-38 0.00287739211841557 3.94115385213976e-12 8.4381940047354 -5.24894858562485 6.0807381473807e-17 358.107110754663 40.4223502524282 8.85913630747266 1.15378943961467e-17 -177.98560615667 254.753428651656 -0.698658334447949 0.485065244900956 ACBD3 other 6.66813745241767e-13 1 1.54319337548462e-13 8.85913630747266 -0.698658334447949 4.10192586606521e-31 688.076507461797 64.0218086339073 10.7475331007343 1.50955061304517e-24 -953.32311514471 317.087244296262 -3.00650099394726 0.00276568102326864 C16orf72 essential 5.67255328018158e-27 1 2.1556382754285e-20 10.7475331007343 -3.00650099394726 0.401910039633184 -1.38020764527139 6.10739339290452 -0.225989641812643 0.821295303506562 -39.2988826661884 29.081308588029 -1.35134505887969 0.177152876892475 PLCXD3 other 1 1 1 -0.225989641812643 -1.35134505887969 0.0459526510270587 -206.348485809971 249.449253484952 -0.827216289193742 0.408475196352191 -1195.72201885624 486.598320657559 -2.45730814944123 0.0143075331745369 RRP7BP other 1 1 1 -0.827216289193742 -2.45730814944123 0.00964176182585582 5.46959072382096 4.01161637915216 1.36343812739565 0.173307407415439 -14.3322486909206 7.4941086560211 -1.91246876029819 0.0563399801151761 VMO1 other 1 1 1 1.36343812739565 -1.91246876029819 1.15207870700446e-49 168.565441917003 16.2140330899984 10.3962685274759 3.36293299799806e-23 -260.849722791609 34.5254784303764 -7.55528191499606 1.79935766486622e-13 ALG12 other 1.74067571841305e-45 2.66430889436741e-09 4.75754131226785e-19 10.3962685274759 -7.55528191499606 0.591268360136007 15.8613024102334 15.9912730644374 0.991872401047731 0.321704830240589 19.2624164356611 29.6303222871882 0.650091357392691 0.515910185360799 LCK og 1 1 1 0.991872401047731 0.650091357392691 0.152911795464564 -377.730670795596 224.883875721487 -1.67966987221176 0.0936010483051137 -853.082839769743 647.273936345726 -1.31796259955397 0.18807602030579 COL18A1 other 1 1 1 -1.67966987221176 -1.31796259955397 1.95700047646318e-09 9.33181461215093 1.54236678946872 6.05032128276398 2.68301620211918e-09 6.03390549843223 3.36580821376621 1.79270627296988 0.0735723259900438 ADGRG3 other 1.58027788474402e-05 1 2.93387821701733e-05 6.05032128276398 1.79270627296988 3.59314127115007e-12 1916.55879061807 258.134380861633 7.4246552676197 4.59745747507242e-13 -663.017371700639 1116.17722333302 -0.594007257844592 0.552763117684811 RPL35A other 3.32185910517824e-08 1 5.6309659154687e-09 7.4246552676197 -0.594007257844592 0.00511892904347857 14.979790049132 7.17310742620191 2.08832646147385 0.0372336521320772 -13.6202087243013 13.5652085437021 -1.00405450313735 0.315799558228982 SLC25A18 other 1 1 1 2.08832646147385 -1.00405450313735 1.60606819968667e-21 32.1480502856707 18.3513110465865 1.7518121841028 0.0804216234635605 -339.114085701128 40.6535349765384 -8.34156453791373 7.24275204903374e-16 ZNF721 other 1.95924259679777e-17 1.09445226212949e-11 1 1.7518121841028 -8.34156453791373 1.12283936243347e-39 156.906627753143 18.1098568719031 8.66415614783677 5.38432212884152e-17 -211.486721435167 39.8499567927479 -5.30707530086091 1.63347358821295e-07 C11orf54 other 1.64215256755895e-35 0.00214132052678835 7.13314995628925e-13 8.66415614783677 -5.30707530086091 1.16813357406319e-17 69.9624160636286 12.4238626348433 5.63129343264114 2.8676920791236e-08 -269.195598662153 43.8596752229302 -6.13765599708352 1.61303616895465e-09 CEP63 other 1.30690784266189e-13 2.24921763399036e-05 0.000301222375991143 5.63129343264114 -6.13765599708352 9.81895705131122e-45 875.219159577274 108.526548786922 8.06456272092144 4.69546466096633e-15 -1368.65298040282 201.882514354669 -6.77945281580136 3.14373426358656e-11 SRPRA other 1.46489020248512e-40 4.53137856753367e-07 6.00972521957081e-11 8.06456272092144 -6.77945281580136 1.32440908705353e-15 323.517558603027 85.6505451795493 3.77718037783457 0.00017633862631935 -814.451098882781 164.531473366913 -4.95012341539372 9.94425703229888e-07 EWSR1 essential 1.39473520957608e-11 0.0126292064310196 1 3.77718037783457 -4.95012341539372 3.6376926992424e-14 174.812396648307 26.4189242511001 6.61693848647255 8.94650085826446e-11 -260.466022219475 101.069563230649 -2.57709654512971 0.0102311111978401 HMGN4 other 3.63987531486195e-10 1 1.03197887400081e-06 6.61693848647255 -2.57709654512971 3.4376082806723e-17 112.208730028196 27.2865925202639 4.11222947478203 4.52203213439721e-05 -308.622534437796 59.6626171840479 -5.17279578074414 3.24351266463587e-07 SPATA13 other 3.79683834600256e-13 0.00420197065703577 0.385684120742738 4.11222947478203 -5.17279578074414 4.18162675508415e-07 37.506243957756 15.8730693233512 2.36288541262653 0.0184861013431512 204.960784284695 37.3524787902385 5.48720703211424 6.28179781320564e-08 GJC1 other 0.00288574062368357 0.000836861104675256 1 2.36288541262653 5.48720703211424 1.84284959476033e-19 118.767307533423 17.7176798826845 6.70332167190209 5.0993467911022e-11 -147.256776570643 36.1737289692714 -4.07082102859049 5.37878484169552e-05 CNOT10 other 2.15816116042383e-15 0.619367074521239 5.92034162446966e-07 6.70332167190209 -4.07082102859049 9.18433285461344e-13 200.90743701218 45.0310402211911 4.46153222366903 9.98497698610534e-06 -392.259287173242 98.7865799524089 -3.97077505226131 8.17501956710158e-05 MTA1 other 8.68837888046432e-09 0.927374219692003 0.0899746276217952 4.46153222366903 -3.97077505226131 0.00453944911152487 -6.85690889239335 11.1717906631356 -0.613769904856846 0.539622540861341 -67.2472852999236 21.3391996110754 -3.15134993465364 0.00171412886728858 ZNF662 other 1 1 1 -0.613769904856846 -3.15134993465364 3.53518679374493e-07 36.7640747066731 72.7869961635804 0.505091247673555 0.613700059377013 -569.880979481334 134.12875709172 -4.24876060762746 2.53041785312962e-05 CADM1 other 0.00245518722825585 0.29752653117098 1 0.505091247673555 -4.24876060762746 7.31689286067906e-10 53.3896627156804 9.3124767113167 5.7331324813731 1.63728693949883e-08 -95.0912178718326 39.7091723915302 -2.39469150689514 0.0169723346781824 ZNF320 other 6.03497323148809e-06 1 0.000173748890019616 5.7331324813731 -2.39469150689514 0.246754988837094 -190.84391331661 496.165218625853 -0.384637830610455 0.700658040357495 -2619.24801090177 1570.05591053719 -1.66825142552128 0.0958487584753355 C12orf60 other 1 1 1 -0.384637830610455 -1.66825142552128 1.29367189006824e-12 663.346197620813 87.4607220786872 7.58450401340169 1.51111802806745e-13 248.024000920707 246.130861941662 1.00769159529248 0.314063238231841 PYCR1 other 1.21747461574322e-08 1 1.87469302562047e-09 7.58450401340169 1.00769159529248 1.36953865372954e-26 149.308381936587 38.2207103860101 3.90647846229561 0.000105420862805906 -549.783802832059 68.8491387419139 -7.98534030894656 8.36211419091373e-15 NAA38 other 1.80806493065374e-22 1.25356453835988e-10 0.869089592971886 3.90647846229561 -7.98534030894656 0.0665344630281478 66.5300372716339 29.0769005034736 2.288071841209 0.0225160671174933 74.3013918968867 55.1083502071634 1.34827828482567 0.178129985667669 SPNS2 other 1 1 1 2.288071841209 1.34827828482567 9.01120912047425e-33 204.991431885975 28.3968236919753 7.21881553055189 1.76698442731519e-12 -570.604971304818 80.7038795184584 -7.07035367704115 4.74713255129001e-12 AP2A2 other 1.26490342424097e-28 6.92179397303596e-08 2.13858125237958e-08 7.21881553055189 -7.07035367704115 0.669225601368034 -9.87649732853394 11.663360233399 -0.846796903370249 0.397482758088426 -16.3635920939557 36.3422077421369 -0.450264117415822 0.652700384685861 SLC8A1 other 1 1 1 -0.846796903370249 -0.450264117415822 9.35352905161836e-16 1.1451644683361 2.62592918722605 0.436098762261679 0.662940992212629 -53.7984260650666 6.6933372492012 -8.03760875361346 5.90130995861678e-15 SLC25A21 other 9.89977514823287e-12 8.85727611688792e-11 1 0.436098762261679 -8.03760875361346 0.111567796351682 11.1931700500507 8.71630641225718 1.28416436052666 0.199637174256356 48.435138477794 25.6509137795807 1.88824222380532 0.0595312156309484 PCP4 other 1 1 1 1.28416436052666 1.88824222380532 1.27237754277371e-14 523.426636867005 90.7512510219953 5.76770712218768 1.35273608515362e-08 -1682.87654481926 440.217417076575 -3.82283044590788 0.000147266363842582 ABAT other 1.29451691201797e-10 1 0.000144093447790564 5.76770712218768 -3.82283044590788 5.6937800652541e-14 297.5355538015 39.5555973211284 7.52195830557141 2.31352070734729e-13 -163.813150493795 111.138324058677 -1.47395735792549 0.141084532586407 SLC25A10 other 5.65392360479732e-10 1 2.85766077771537e-09 7.52195830557141 -1.47395735792549 1.4899891244638e-11 180.667643439581 25.0719566799291 7.20596504477097 1.94634860839795e-12 38.088887817005 141.731942791841 0.268738909992544 0.788233056271033 CAMK1D other 1.33830823159338e-07 1 2.35196765838808e-08 7.20596504477097 0.268738909992544 4.66618341142982e-26 108.114119757926 9.57038267105334 11.296739479909 1.00398484888788e-26 38.0203143934213 30.1877624760448 1.25946116157472 0.208404903742138 LYSMD4 other 6.12016616243135e-22 1 1.4523644824012e-22 11.296739479909 1.25946116157472 5.8525501573441e-08 5.04295724804677 1.71742399749701 2.93634958833486 0.00346125937829906 -9.87215760395998 3.278763321192 -3.01093938075742 0.00272510877648171 WBP2NL other 0.000431449997599407 1 1 2.93634958833486 -3.01093938075742 0.0119795889703488 5.39103880831855 1.90815398681485 2.82526402248984 0.00489959470456681 -2.06973228356439 5.61543973776799 -0.368578843370699 0.712586657170633 IGSF5 other 1 1 1 2.82526402248984 -0.368578843370699 4.06527580879837e-10 3.49543510601438 3.26420377535377 1.07083850965632 0.284723095464627 59.459372169525 9.0363564035437 6.58001627140419 1.11926476731984e-10 NKX2-5 other 3.4014162692216e-06 1.59842201420947e-06 1 1.07083850965632 6.58001627140419 0.00161769766979364 100.356893098462 45.3505994197348 2.21291216395236 0.0273227033816305 -320.425203762604 134.134620479589 -2.38883296957151 0.0172456302199757 AFMID other 1 1 1 2.21291216395236 -2.38883296957151 0.101066613832706 46.8003547680654 73.3900733777102 0.637693254879338 0.523945182100887 -385.553210533637 210.996381937174 -1.82729773370445 0.068209839479102 GAS6 other 1 1 1 0.637693254879338 -1.82729773370445 0.734684278448053 1051.55753686617 1558.85361635918 0.674571060316854 0.500253989054752 -615.685561307562 3827.75343103591 -0.160847758979328 0.872277001659624 NEB other 1 1 1 0.674571060316854 -0.160847758979328 0.694592980875421 2.90802783894859 5.42440699969529 0.536100598482367 0.592108561750181 -4.61957060333122 11.1547638752162 -0.414134324581718 0.67893927049308 BEGAIN other 1 1 1 0.536100598482367 -0.414134324581718 0.535549895001172 20.4034038222887 25.7585206998738 0.792103089304683 0.428652297871267 63.8172657571999 63.1777138848389 1.01012306133025 0.312893811206565 GPC6 other 1 1 1 0.792103089304683 1.01012306133025 0.000160312074565083 17.5475080524793 42.0390110462587 0.417410105893558 0.676541945387205 -380.354988840412 100.199540951999 -3.79597536302709 0.000163473485331835 ARHGEF37 other 0.848852434822112 1 1 0.417410105893558 -3.79597536302709 0.502895246747742 0.939230981863937 5.39986769474039 0.173935924907711 0.861980287743157 9.5306975708132 8.82656461480834 1.07977429348034 0.280719437820766 FAM43B other 1 1 1 0.173935924907711 1.07977429348034 0.423854901203596 11.2131781837094 9.70879106180638 1.15495102452263 0.248641955777314 4.81601389964141 20.9283694348616 0.230118926112758 0.81809002925185 CSMD1 other 1 1 1 1.15495102452263 0.230118926112758 2.80478645370323e-10 15.6871850051312 3.00019911827427 5.22871462416622 2.47389382766626e-07 -13.8276934634037 7.49416434737324 -1.84512813203121 0.0655851269193339 PTGDR2 other 2.36639833098941e-06 1 0.00247166732322136 5.22871462416622 -1.84512813203121 1.27772261173211e-49 72.7946214099217 5.10958920548213 14.2466680749638 3.17663370352878e-39 -8.58517573809977 12.6175076907761 -0.680417713902081 0.496537126767747 CEP57L1 other 1.93012777728253e-45 1 4.79417558536563e-35 14.2466680749638 -0.680417713902081 0.00151375914813498 21.3569290059288 6.76243356004099 3.15817210125748 0.00167704841923493 -22.2010397688546 20.6332262867645 -1.07598489253694 0.28241808379548 RIPPLY3 other 1 1 1 3.15817210125748 -1.07598489253694 4.46239731779991e-25 34.6194138823425 3.15402375521881 10.976269225956 1.91328823281172e-25 17.0780143077626 10.083120856576 1.69372305962442 0.0908935244014232 GPR19 other 5.76854101271994e-21 1 2.74690791584779e-21 10.976269225956 1.69372305962442 2.92926219409744e-15 3.09537074716561 0.760967961437846 4.06767551858151 5.48369695751508e-05 -27.6746519206724 4.3924726348534 -6.300472244512 6.32045130340284e-10 GJD3 other 3.04936194405543e-11 8.89666725466984e-06 0.464419399393453 4.06767551858151 -6.300472244512 1.08908776695535e-29 96.9276101862833 7.92104156985541 12.2367253512662 1.40564987422816e-30 62.8563643883611 62.0553898979356 1.01290741209979 0.311555510354803 RABIF essential 1.48616916678728e-25 1 2.07080339471292e-26 12.2367253512662 1.01290741209979 0.00202837755598446 -169.468700695031 53.1579532024928 -3.18802155623787 0.0015143873932174 -298.561769840343 122.288207424457 -2.44146002405651 0.0149438811355611 TMEM119 other 1 1 1 -3.18802155623787 -2.44146002405651 1.00933212828353e-17 124.468234708121 19.1984247475828 6.4832524722526 2.03659880933968e-10 -197.085359508544 50.4173886152163 -3.9090751211391 0.000104506249307341 FANCF other 1.13105758295452e-13 1 2.32233362229003e-06 6.4832524722526 -3.9090751211391 2.42347227256354e-19 107.106617986682 27.7714714617279 3.85671382714764 0.000128624029295117 -319.398847174517 54.0538762225433 -5.90889811231171 6.06620710043186e-09 SMDT1 other 2.83085796158147e-15 8.34285462522393e-05 1 3.85671382714764 -5.90889811231171 0.0554938187578045 14.6416263487971 6.58469299578286 2.22358526937768 0.0266052429275676 3.1372282587863 11.8242756955777 0.265320966759903 0.790867360779128 C2CD4C other 1 1 1 2.22358526937768 0.265320966759903 0.0116739476675928 26.1588960851009 11.4830491565736 2.27804442255879 0.0231087876957912 -4.89790723902666 25.0924018007935 -0.195194835389244 0.845312903187014 CHST6 other 1 1 1 2.27804442255879 -0.195194835389244 0.601967166900783 0.607464121611944 10.3143869829795 0.0588948352058502 0.953058761443491 -22.7315520649894 25.3930335972064 -0.895188516093258 0.371105332334663 POTEC other 1 1 1 0.0588948352058502 -0.895188516093258 6.30798714997981e-15 412.440475874038 54.2381589328219 7.60424918524386 1.25979203587309e-13 -232.591294689066 178.238850364898 -1.30494162306868 0.192462421178161 RUVBL2 essential 6.49659596576421e-11 1 1.56516562536872e-09 7.60424918524386 -1.30494162306868 2.51553197563658e-66 75.9016129810305 4.22140522715821 17.9801769545177 4.4621222799411e-57 -170.481580365239 26.290770262485 -6.48446502948235 2.0012668004102e-10 GDPGP1 other 3.88549068956827e-62 2.84600151686335e-06 6.88237740458115e-53 17.9801769545177 -6.48446502948235 0.578872296405513 -4.91743969433117 6.14714762759456 -0.799954709442274 0.424094087457023 -13.3475056514591 14.9478568863448 -0.892937747059402 0.372294242076936 CTNNA3 other 1 1 1 -0.799954709442274 -0.892937747059402 0.1295944700345 3.27323497477692 2.23039711558565 1.46755703363499 0.142811108382396 -10.8212813285492 9.90397982206622 -1.09261948458732 0.27505174132249 WT1-AS other 1 1 1 1.46755703363499 -1.09261948458732 3.06638659529156e-06 5.49397544838451 1.83845135384994 2.9883714012228 0.00293596329242409 -8.75840226918876 3.97518960463366 -2.20326654582201 0.0280095143445452 RIMBP3C other 0.0195758120243413 1 1 2.9883714012228 -2.20326654582201 8.33487980077174e-11 21.0288133937419 53.7274878184389 0.39139766714581 0.695656856374176 -894.603146615182 140.579897178508 -6.36366340117047 4.19159673859774e-10 PRR36 other 7.21800590746833e-07 5.92104955294316e-06 1 0.39139766714581 -6.36366340117047 1.22065653481273e-11 24.59719408742 3.52784784074071 6.97229449733172 9.07041390245138e-12 -5.05107095587319 10.1255741447548 -0.498842918304018 0.618091697654837 LINC01547 other 1.10103219440109e-07 1 1.07774657988927e-07 6.97229449733172 -0.498842918304018 5.57315036260882e-18 1394.92341631003 156.816560086099 8.89525580426043 8.65118360480387e-18 -268.599652367756 450.897014636226 -0.595700667001437 0.551623417129075 PTTG1IP other 6.28818555413153e-14 1 1.15977767406001e-13 8.89525580426043 -0.595700667001437 1.65600937383261e-25 264.475257146598 30.6868934843618 8.61850865684324 7.58331729592796e-17 -336.527705842107 87.3958305996505 -3.85061510981798 0.000131998028062153 DDX41 essential 2.15513059910576e-21 1 1.00221121382984e-12 8.61850865684324 -3.85061510981798 2.1497207845075e-25 25.8849586637699 2.30857144178839 11.2125439114492 3.15421244527949e-26 1.13716869518438 17.9004396444404 0.0635274170786954 0.94937146723776 ABHD16B other 2.79291724323215e-21 1 4.55026687356019e-22 11.2125439114492 0.0635274170786954 0.63956688293659 -0.965693028382481 2.01884586897954 -0.478339155663531 0.632607580204776 -7.06060165980254 8.02590859975672 -0.879726148391044 0.379409409794983 PLGLB1 other 1 1 1 -0.478339155663531 -0.879726148391044 1.56176519516324e-32 633.605523026904 126.757256481604 4.99857397212489 7.80860404015307e-07 -3747.84373271241 371.838764323863 -10.0792173713447 5.15269050756654e-22 DAZAP2 other 2.18772068538466e-28 7.98203286527132e-18 0.00756497559410029 4.99857397212489 -10.0792173713447 0.00856209043600254 0.0749347795257948 4.23413479139063 0.0176977784642476 0.985886465690383 -25.9604582612759 9.25116356375383 -2.80618303658464 0.00519347335113018 CCBE1 other 1 1 1 0.0176977784642476 -2.80618303658464 2.69359464036846e-30 632.158926386761 79.7185615433438 7.92988375791313 1.25669998028755e-14 -865.169479452156 154.891909089589 -5.58563377866138 3.68579884055089e-08 SELENOF other 3.6939956898013e-26 0.000494855352332363 1.59638598495927e-10 7.92988375791313 -5.58563377866138 6.66815648487192e-40 296.624594147152 20.4268623650477 14.5212998866975 3.54154479819836e-40 -90.867923068129 138.779906361594 -0.654762821581466 0.512918575477965 ZNF623 other 9.76351472514946e-36 1 5.35446158039611e-36 14.5212998866975 -0.654762821581466 0.0107957584226781 17.8679894314712 13.1503422365907 1.35874710406804 0.174792963282292 -57.8172959697683 27.2447798079119 -2.12214216365141 0.0342795537713158 EPHA10 other 1 1 1 1.35874710406804 -2.12214216365141 8.92067760895809e-44 164.068766748583 31.2970595565093 5.24230611672462 2.288120344886e-07 -748.863558384943 67.3967259958858 -11.1112750258916 6.02597022836904e-26 CCDC125 other 1.32659396722816e-39 9.39448758602733e-22 0.0022899508411619 5.24230611672462 -11.1112750258916 2.4179281403756e-12 79.3754466357479 14.6114846154591 5.43240120526615 8.43528831238255e-08 -35.4121005865638 28.8186804331186 -1.22878980072481 0.219687835405999 JRKL other 2.2506075130616e-08 1 0.000865629286616697 5.43240120526615 -1.22878980072481 0.881209137464437 -1.57649246635864 3.28553995558281 -0.479827513185423 0.631547254514548 -0.357765280024969 6.78756244208737 -0.052708948621465 0.957983594692883 GBP6 other 1 1 1 -0.479827513185423 -0.052708948621465 8.46002291608687e-22 112.682507930796 21.5325661313581 5.23312025345158 2.38349803498142e-07 -340.244816302152 52.9418262406035 -6.4267676516456 2.85098859067292e-10 KIAA2026 other 1.03821401226218e-17 4.04213162385607e-06 0.00238325968517792 5.23312025345158 -6.4267676516456 0.400062882770344 22.5422182727747 59.4875490858488 0.378940107958443 0.704881563873894 -138.378383632928 123.743258189902 -1.11827008321186 0.263949809762584 FHL3 other 1 1 1 0.378940107958443 -1.11827008321186 1.54982455447216e-06 9.89764525916951 1.89167321899646 5.23221725601225 2.39157774487765e-07 8.00390840717877 4.57027671460192 1.75129623587265 0.0804563892357725 PMCH other 0.0101652992527829 1 0.00239086027155419 5.23221725601225 1.75129623587265 2.42273652003839e-08 1.39522190764814 1.97304530803349 0.707141342354039 0.479782003873104 -24.8061083793563 4.73489355208653 -5.23900022386458 2.3138197875977e-07 C19orf71 other 0.000183183108280103 0.00301282474543097 1 0.707141342354039 -5.23900022386458 2.72913685900384e-12 133.638851461726 34.3073462077133 3.89534214196025 0.00011031580015987 -592.386416046433 115.700456352484 -5.12000068730685 4.25147117077996e-07 CCDC159 other 2.53618688307226e-08 0.00548439781030615 0.90789903531573 3.89534214196025 -5.12000068730685 8.16463098415397e-08 98.4600063773748 17.0245670403258 5.7834073632624 1.23440101771469e-08 76.7927728968111 53.8658239525622 1.42563071093909 0.154547446443145 RIPK4 other 0.00059389525778736 1 0.000131648868539272 5.7834073632624 1.42563071093909 7.71113042873256e-08 1.42454051244225 0.976889537819483 1.45824113913839 0.145352226026165 -9.69392314922538 2.13159547595711 -4.5477311518841 6.69279698905896e-06 LRIT3 other 0.000562218519558891 0.0816655088604975 1 1.45824113913839 -4.5477311518841 7.16039788765881e-22 438.088818332172 50.4863250026814 8.67737586978068 4.80175158007386e-17 -276.067992778368 105.01932666364 -2.62873512475059 0.00881481693214054 SF3A3 essential 8.80370920287651e-18 1 6.36760277033595e-13 8.67737586978068 -2.62873512475059 0.97771609324764 -0.995048252008653 8.21191471318278 -0.121171284257407 0.903600525949334 -8.59992741686074 42.4898282714802 -0.202399674621258 0.839680655419941 GRIN2A other 1 1 1 -0.121171284257407 -0.202399674621258 1.48019009310208e-07 86.60617764646 36.3011973560196 2.38576641968805 0.0174018998449738 -312.997173999365 82.9961038358087 -3.77122731711079 0.000181173922786667 GTF2H2C essential 0.00105863195458661 1 1 2.38576641968805 -3.77122731711079 4.88321825570137e-56 159.752209072007 9.61886016444084 16.6082265820416 2.32868817429738e-50 -87.0238290869734 31.9406439590089 -2.72454835909557 0.00664725251866301 ASB7 other 7.46106917288612e-52 1 3.56941323356303e-46 16.6082265820416 -2.72454835909557 4.76731466180074e-05 7.14080973904199 2.78861482779876 2.56070134457353 0.010715859829133 28.5752290586622 6.7365279489143 4.24183337104206 2.60721117508909e-05 SH2D7 other 0.27035441447072 0.306321240961217 1 2.56070134457353 4.24183337104206 0.102347489350401 -8.77456514172844 7.3249943912465 -1.19789376934052 0.231503042481597 -33.5167353356469 15.967150486629 -2.09910562086292 0.0362881860622956 GPR132 other 1 1 1 -1.19789376934052 -2.09910562086292 0.000117055876032718 158.29220022704 42.9756795842935 3.68329719874614 0.000253284912364049 372.368038175015 126.43401245156 2.94515716898313 0.00336626525395143 MX2 other 0.63058000418825 1 1 3.68329719874614 2.94515716898313 8.19616005619379e-12 152.597099830633 40.6055466173027 3.75803584837369 0.000189939414769031 -461.819938910267 95.718106999144 -4.82479181200686 1.82698924855111e-06 EP400 other 7.46588219518692e-08 0.0229159261445766 1 3.75803584837369 -4.82479181200686 5.32340064528698e-10 27.266296052097 6.72852170407741 4.05234570850443 5.81832699766168e-05 88.4395863280901 14.155556488355 6.24769406987597 8.47405746415125e-10 MEX3B other 4.42693997662065e-06 1.1890797433697e-05 0.491532264762459 4.05234570850443 6.24769406987597 3.14857558608335e-22 48.9825786659382 9.11318436887835 5.37491360684136 1.15433406011263e-07 -98.3803427748537 18.8745559954474 -5.2123262024592 2.6854927132559e-07 PI4KAP2 other 3.89604743021954e-18 0.00348979778087604 0.00117372687232252 5.37491360684136 -5.2123262024592 0.0702024303642184 22.0126004038169 49.6057098640987 0.443751343628049 0.657403815698322 -299.266321160355 149.636282615867 -1.99995827167536 0.0460155514943855 FAM46C other 1 1 1 0.443751343628049 -1.99995827167536 5.0467140413561e-13 48.1505354650048 10.9792208914855 4.38560585864032 1.38865548904283e-05 -206.405076759923 37.8258977752466 -5.45671322823158 7.37235355597163e-08 COA5 other 4.81961190949507e-09 0.000980228128801988 0.123715317518826 4.38560585864032 -5.45671322823158 3.81868517203769e-26 207.569387266586 20.4366750982351 10.1567102412129 2.70680004338193e-22 -81.5225630434679 43.7417402117427 -1.86372473177422 0.0629038940398769 UTP11 other 5.01278802533387e-22 1 3.79736978086052e-18 10.1567102412129 -1.86372473177422 1.49947471763827e-16 176.340332194395 20.3033978076526 8.68526213518457 4.57620489594994e-17 207.611669086238 61.8195220917303 3.35835124668508 0.000839813409192295 PSMG1 essential 1.62408106667401e-12 1 6.0707934149672e-13 8.68526213518457 3.35835124668508 7.38906177207652e-34 279.673447813363 36.7094991333695 7.61855798678374 1.14860569165904e-13 -465.15482100454 76.3250952804122 -6.09438899873756 2.08397977426532e-09 PRR14L other 1.04562613136655e-29 2.89860746802563e-05 1.42817631700886e-09 7.61855798678374 -6.09438899873756 0.0030364490387623 23.4498924268015 6.88256250264066 3.40714558244903 0.000704742265771696 21.4242390671923 36.2035595502556 0.591771619513061 0.554248022297416 ACSM5 other 1 1 1 3.40714558244903 0.591771619513061 0.684345343734879 3.34717041548935 4.56147315557459 0.733791540875071 0.463391920803989 -9.44370838526531 26.130948819647 -0.36139936787006 0.717941236959944 BPIFA4P other 1 1 1 0.733791540875071 -0.36139936787006 0.0229825905651231 -481.005546849452 399.58669188417 -1.20375767416419 0.229203919403981 -2146.28032353986 779.470014488042 -2.75351236564186 0.00609197242312868 SERHL2 other 1 1 1 -1.20375767416419 -2.75351236564186 9.33015373072502e-06 22.8736081754654 4.70192099637478 4.86473681567623 1.5066755672164e-06 16.5944906646572 17.1153364534994 0.96956847501904 0.332696499856756 PCBP3 other 0.0569139377574226 1 0.0143345113464969 4.86473681567623 0.96956847501904 9.5107205953491e-43 254.45771751582 28.1745688297532 9.03146802541676 2.96259934189124e-18 -458.689392856169 57.9282877166772 -7.91822805292611 1.37098645575155e-14 SETD3 other 1.40920347061288e-38 2.05085863915874e-10 3.99358391286939e-14 9.03146802541676 -7.91822805292611 0.0404258388626397 16.06666739158 9.3543630438315 1.71755867463095 0.0864504606692852 -20.1053078760438 19.0516915706161 -1.05530303183433 0.291758668539781 TNFAIP8L3 other 1 1 1 1.71755867463095 -1.05530303183433 5.92005037861881e-09 65.342702185421 25.2802533944975 2.58473288086754 0.01000711995835 -183.901471228101 48.8641555406975 -3.76352500505068 0.000185921371813263 ZNRF3 other 4.64427952202645e-05 1 1 2.58473288086754 -3.76352500505068 0.0140273798415345 61.8688552857834 47.4445097442563 1.30402559999629 0.192777367426016 -580.098044324813 239.182530213532 -2.42533618072744 0.0156192173582041 FBXL7 other 1 1 1 1.30402559999629 -2.42533618072744 6.65333014065046e-32 123.132103710661 15.121685866154 8.14274974368169 2.70735223532812e-15 -134.768576950707 30.745472697288 -4.38336330937578 1.40579785550948e-05 TANGO2 other 9.2640968878417e-28 0.168189655433155 3.47813541672604e-11 8.14274974368169 -4.38336330937578 1.5707928381145e-13 44.2435349486755 5.62181542042393 7.86997288952954 2.01020155158446e-14 41.1218816316795 34.1512304829589 1.20411127359522 0.229084047136492 SMG1P5 other 1.53419336498643e-09 1 2.54029170073729e-10 7.86997288952954 1.20411127359522 2.71536419576026e-18 114.683560935524 17.7974758610754 6.4438104499047 2.57945456155276e-10 -124.886603427289 33.0702950365225 -3.77639822352251 0.000176742497939774 SFXN4 other 3.08655448132068e-14 1 2.93335572739779e-06 6.4438104499047 -3.77639822352251 0.201558536310101 9.77502619502478 5.45355121787884 1.79241485125848 0.0736293118218623 7.62690388476015 10.0901339064761 0.755877370454422 0.450054159311426 FAM167B other 1 1 1 1.79241485125848 0.755877370454422 9.93199400773038e-11 40.617983048884 23.8831683609663 1.70069491765039 0.0895717977417018 -318.930528445518 57.2316253595079 -5.57262748422947 3.95264603684826e-08 MRPL54 essential 8.55939243586204e-07 0.000530286992303562 1 1.70069491765039 -5.57262748422947 0.000495748887891887 19.270919657456 5.37703002192255 3.58393380339835 0.000368924877860396 -14.8441917864905 19.5322279898402 -0.759984564700545 0.44759364470997 ZNF438 other 1 1 1 3.58393380339835 -0.759984564700545 6.9139682792263e-31 363.862474268111 29.7738280099415 12.2208831913255 1.70759866263238e-30 -62.3255306146377 95.8295632072449 -0.650378949133368 0.515724075906823 HMCES other 9.53643644753684e-27 1 2.51460979059244e-26 12.2208831913255 -0.650378949133368 7.43895721427805e-16 111.470761802575 22.906271355948 4.86638615558134 1.49691709829699e-06 -153.4768495211 44.4585572562381 -3.45213292992239 0.000600088768147855 DGCR6 other 7.89719697867758e-12 1 0.0142461600244925 4.86638615558134 -3.45213292992239 2.05420583831784e-32 31.3787680039395 2.44804279481631 12.8179001079489 4.70638966477308e-33 3.98617269705383 12.3869598869538 0.321803956211416 0.74772483219548 ZNF530 other 2.87362854722282e-28 1 6.99134184702041e-29 12.8179001079489 0.321803956211416 2.49393877630391e-15 129.988275573434 30.6186384071312 4.24539699790043 2.56443917405096e-05 -313.595856714625 62.4709163935096 -5.01986964204684 7.00983108402924e-07 NDUFB1 other 2.60142753756261e-11 0.0089655739564734 0.223465229626801 4.24539699790043 -5.01986964204684 4.67613148976557e-10 62.8226181378673 9.66054762267406 6.50300796514037 1.79809258015063e-10 4.79965815474534 25.2718911442727 0.18992081468478 0.849442683337729 KLHL25 other 3.90223172820937e-06 1 2.05539962837019e-06 6.50300796514037 0.18992081468478 1.66020361750626e-53 120.673738935923 6.92282033480153 17.4312972314603 3.34896386486238e-54 -126.485891651696 79.3068949351464 -1.59489148774682 0.111328146440562 TRMT12 other 2.52666388548278e-49 1 5.15372049163671e-50 17.4312972314603 -1.59489148774682 8.23380633268603e-06 20.7666531365333 4.69027947849956 4.42759396998164 1.15654412079524e-05 -33.3320240032784 23.0097928136675 -1.44860165726827 0.148036877828846 GUSBP1 other 0.0503999340562105 1 0.103718876752917 4.42759396998164 -1.44860165726827 0.00118040692075025 -0.558435701400225 4.21542891617628 -0.132474230381939 0.894658009355138 -36.0532858001891 10.0386484197096 -3.59144820027795 0.000358519705589119 GPR1 other 1 1 1 -0.132474230381939 -3.59144820027795 0.251342518622266 2.36026428336438 2.54714491126172 0.926631332567264 0.354531165356054 -5.73792356618055 5.5769443499792 -1.02886512866171 0.304002822844991 BMP8A other 1 1 1 0.926631332567264 -1.02886512866171 3.83475476769062e-27 447.406076670414 40.2568048752635 11.1137999664084 6.20255028867763e-26 637.139855171732 113.290192985732 5.62396301374451 3.02626621212921e-08 ALYREF essential 5.09792298816791e-23 0.000407365694814712 8.93229267072466e-22 11.1137999664084 5.62396301374451 0.28561535017843 1.26881276329939 30.8092556818516 0.0411828437662253 0.967165610617017 81.1123295409412 56.2535278209475 1.44190653782849 0.149918251462435 RFLNB other 1 1 1 0.0411828437662253 1.44190653782849 0.0601442508072761 37.9153518149145 16.8379539456327 2.25177904259256 0.024734327941705 82.3342923680685 68.3308031678766 1.20493669839922 0.228751651950216 UPP1 other 1 1 1 2.25177904259256 1.20493669839922 0.200254096237413 -13.0110769861044 9.47069774834544 -1.373824540898 0.17007473661708 1.87812989596575 17.1055594984033 0.109796460977558 0.912612201597705 OPCML other 1 1 1 -1.373824540898 0.109796460977558 1.61959197566924e-23 74.2566362505184 14.126481657274 5.2565555990569 2.15105414476207e-07 -266.478878856522 37.2877283755257 -7.14655707027272 3.04631063613645e-12 TRIM52 other 2.04667837965322e-19 4.4540107810951e-08 0.00215643178012398 5.2565555990569 -7.14655707027272 1.99743198240621e-15 493.666754264636 84.6457016322077 5.83215384532646 9.45755038810304e-09 -281.098658994464 184.239960525199 -1.52572036051873 0.12766824483513 CMTM4 other 2.09011282638986e-11 1 0.00010130927975736 5.83215384532646 -1.52572036051873 7.49437010375932e-20 188.862856849554 84.4504891166306 2.23637374780298 0.0257348704263035 -935.165504688264 134.599445058628 -6.94776642118348 1.07215343470326e-11 TMEM50A other 8.84935221851901e-16 1.55612349512832e-07 1 2.23637374780298 -6.94776642118348 0.0893008015528172 14.8360384066098 15.7921498377421 0.939456537523018 0.34791180738951 -41.2903922579157 31.5369524372657 -1.30927020738772 0.190993540634735 ASCL2 other 1 1 1 0.939456537523018 -1.30927020738772 1.60130464919062e-23 133.869491312662 14.0716805406529 9.51339755943963 6.7174617898735e-20 -206.531779389924 58.992097009697 -3.50100759015186 0.000503117193960047 TBK1 other 2.02404907657695e-19 1 9.22710551457024e-16 9.51339755943963 -3.50100759015186 4.62294351182075e-18 567.274949826672 77.0025428692486 7.36696385195892 6.52954394904475e-13 -246.719029374201 159.994545283725 -1.5420465050023 0.123644838240116 CBX6 other 5.22300157965509e-14 1 7.96604361783460e-09 7.36696385195892 -1.5420465050023 9.72301665762241e-08 170.0614212768 33.3854642127645 5.09387619093757 4.85061085325417e-07 -208.491879343682 144.204880440813 -1.44580321211289 0.148810373438788 MACC1 other 0.000703557485345558 1 0.0047632998578956 5.09387619093757 -1.44580321211289 3.78140707460723e-24 300.119167870954 29.7078902295603 10.1023386565608 4.22585033573901e-22 -78.7334391963548 135.870249512917 -0.57947519400757 0.562509350707787 TBL3 essential 4.82431914578391e-20 1 5.91914856526963e-18 10.1023386565608 -0.57947519400757 2.75600226735493e-10 117.818623179805 28.6604390467739 4.11084502186185 4.55790399038637e-05 -151.368918602222 54.9948163079961 -2.75242156923458 0.00611533106175303 KREMEN1 other 2.32606591364756e-06 1 0.388606894220342 4.11084502186185 -2.75242156923458 5.56444017302939e-08 38.4309910348588 6.97886843576162 5.50676537157914 5.7192935523413e-08 11.5303496211199 12.663977577039 0.9104840521848 0.362983532057159 TRAIP essential 0.000411045195581681 1 0.000592404426151512 5.50676537157914 0.9104840521848 1.40281807668896e-21 101.938938919303 11.4918744690033 8.87052318525235 1.07954526837617e-17 -4.13747495913852 22.184987423401 -0.186498864307413 0.852124002050636 CHEK2 ts 1.71340199886789e-17 1 1.44507929624835e-13 8.87052318525235 -0.186498864307413 1.30897470082755e-07 16.6142629962314 3.82225900826152 4.346713019793 1.65668637390807e-05 -8.05874233611443 7.79541935326003 -1.03377919402685 0.301709983893261 AIFM3 other 0.000939189347843765 1 0.146600177227125 4.346713019793 -1.03377919402685 0.0285903369868637 177.059971134362 68.0555897952929 2.60169622608441 0.00953234801476412 -23.3365463921023 203.9060868616 -0.114447522147496 0.90892582190044 B3GALT5 other 1 1 1 2.60169622608441 -0.114447522147496 1.22660517573393e-37 2572.70022348322 183.766291363754 13.9998484182864 2.67433934060703e-37 906.219581624435 1074.75214265137 0.843189369586954 0.39956460989645 ZNF703 other 1.7767375970506e-33 1 4.01792742532801e-33 13.9998484182864 0.843189369586954 0.630711736149086 6.93788199305076 7.263878110453 0.955120926804496 0.339940774350318 6.51582778501768 43.8783053075704 0.148497708362805 0.882005022366171 SLC35F3 other 1 1 1 0.955120926804496 0.148497708362805 0.000383683785069771 2.79252649421489 1.85539024687098 1.50508848417433 0.132895904752114 -11.6288993932233 4.19581288346807 -2.77154861672749 0.00577474698784149 C9orf66 other 1 1 1 1.50508848417433 -2.77154861672749 0.117444834578098 11.7833686738632 7.29431931681349 1.61541717082531 0.106801232435779 -3.49703079613586 14.0912077630874 -0.24817111882322 0.804095834262392 TUBA8 other 1 1 1 1.61541717082531 -0.24817111882322 0.00199097768891768 16.5788680617397 10.7468134452893 1.54267757099726 0.123515007221075 218.179350616133 64.1814214782228 3.39941599283778 0.000726948765151721 EMILIN3 other 1 1 1 1.54267757099726 3.39941599283778 0.058847628667676 -32.5335466008999 13.8194567196047 -2.35418419558758 0.0189166866270735 -40.6743600170806 32.0029847812979 -1.27095520293001 0.204285798813648 OLFML1 other 1 1 1 -2.35418419558758 -1.27095520293001 0.19742158848016 -1.13215895626913 0.64565705112232 -1.75349894235825 0.0800816418041721 -0.588046323776049 2.01901543417357 -0.291254001243805 0.770968490756221 FAM162B other 1 1 1 -1.75349894235825 -0.291254001243805 8.23589272930628e-16 71.4245664783721 8.36330196325563 8.54023527934034 1.44275029426903e-16 -67.7747743351265 93.6052004463944 -0.72404924098143 0.469356792672415 RBM12B other 8.73169347161052e-12 1 1.89562961164008e-12 8.54023527934034 -0.72404924098143 0.210710269131967 -9.6084518690918 5.49542298374628 -1.74844627929653 0.0809487770654292 -4.5965824873611 11.1985063304103 -0.41046389149942 0.681626707811221 CCR4 other 1 1 1 -1.74844627929653 -0.41046389149942 1.1275674377652e-06 36.7631045853274 6.97521707110256 5.27053197206324 1.96706749604735e-07 42.3214526962509 44.3269797028159 0.954756064590668 0.340126692730584 LIN9 other 0.00748817535419867 1 0.00197572259302996 5.27053197206324 0.954756064590668 1.06661187998151e-08 27.3423769669127 15.8333023053674 1.726890350451 0.0847550225562762 -275.705589169488 54.5416001180415 -5.0549596743182 5.89038917332604e-07 BTBD9 other 8.23104387781729e-05 0.00755795834829465 1 1.726890350451 -5.0549596743182 4.04586584615207e-06 42.0664535030792 19.765603569478 2.12826556776835 0.0337846438099839 -145.66768541765 42.9567536839026 -3.39103104693492 0.000749265146524873 NUDT14 other 0.0255091841599888 1 1 2.12826556776835 -3.39103104693492 0.00474482017965905 -6.45486541394063 10.1771017741022 -0.634253794176099 0.526182803623167 -106.295617768726 32.3507075840707 -3.28572775394457 0.00108297075460092 MAATS1 other 1 1 1 -0.634253794176099 -3.28572775394457 0.00492353708136133 41.5077883817933 18.5085437335095 2.24262853844325 0.0253242057866082 -68.8348352038247 43.4089020617413 -1.585730850919 0.113383604312844 GPR39 other 1 1 1 2.24262853844325 -1.585730850919 0.0128831641976697 106.158486571687 40.8814254661336 2.59674131616641 0.00966631197994938 -99.5699287082775 120.271006568294 -0.827879732192466 0.408102314799541 FAM3B other 1 1 1 2.59674131616641 -0.827879732192466 6.85743940788677e-09 11.5500022815414 1.85559647092068 6.22441487820395 9.77134072281771e-10 10.2520319333182 7.25255447465566 1.41357530910582 0.158068216547698 ZNF730 other 5.36457484878982e-05 1 1.08882049674358e-05 6.22441487820395 1.41357530910582 1.97680414765268e-10 195.167936946608 28.6675511948869 6.80797378261656 2.62863974656626e-11 139.947358343974 257.347982790195 0.543805927004556 0.586798228645867 IQGAP3 other 1.68423713380008e-06 1 3.08024005502635e-07 6.80797378261656 0.543805927004556 3.30435549953066e-22 88.3546095478959 49.088648971401 1.79989898681814 0.0724294992661339 -744.313778088004 92.0968820034475 -8.08185643092827 4.13729526592251e-15 TOB2 other 4.08682688181952e-18 6.21587240752198e-11 1 1.79989898681814 -8.08185643092827 0.322077776923947 -3.04339358461486 8.20317863012957 -0.371001744791553 0.710781196666076 24.2354842965713 19.4623183237059 1.24525166495974 0.213577346330075 ARSI other 1 1 1 -0.371001744791553 1.24525166495974 2.81834151592588e-07 18.2702811224641 5.10867681886579 3.57632353156378 0.000379570741955332 -47.9527397432001 14.6902327470506 -3.26426004059247 0.00116660594772017 TTC32 other 0.0019697388854806 1 1 3.57632353156378 -3.26426004059247 0.343326230954612 -3.41579739910972 3.55231306646808 -0.961569922243907 0.336695256888199 -13.2537253369119 9.42336130306118 -1.40647534469537 0.160157161445868 LRRC55 other 1 1 1 -0.961569922243907 -1.40647534469537 0.00164065611596839 41.9482323613473 13.3568169334088 3.14058600716643 0.00177772244911829 -4.72549156003774 24.0428534264178 -0.196544539711142 0.844257377432834 DNAH2 other 1 1 1 3.14058600716643 -0.196544539711142 0.0411138680869744 12.5079878484801 28.6024630602282 0.437304571363033 0.662065313586696 -203.476185198476 91.592501824795 -2.22153758380463 0.0267283978626074 HTR7P1 other 1 1 1 0.437304571363033 -2.22153758380463 2.97332234440086e-11 111.279122460228 18.5427850940136 6.00120865857167 3.57069629074707e-09 -80.654267687556 42.1238911570557 -1.91469176925851 0.0560540900934723 KMT5A other 2.6346609293736e-07 1 3.88598877322003e-05 6.00120865857167 -1.91469176925851 0.000941081172861967 7.35067620966387 2.74463186851172 2.67820114383857 0.00762901246240568 21.3439731074477 6.43956397167234 3.31450595123209 0.000980115977846213 KCNH8 other 1 1 1 2.67820114383857 3.31450595123209 2.1282768354101e-11 235.147384031988 40.647427153365 5.78504964520297 1.22880108223373e-08 -94.0530585331061 87.4709363958872 -1.07524924744636 0.282743338120286 SMTN other 1.89842293718581e-07 1 0.000131076211441872 5.78504964520297 -1.07524924744636 0.384791707818746 10.9987130499919 8.48372432963104 1.29644866130041 0.195371649277811 -1.04887399621664 38.8144407817454 -0.0270227774789924 0.978451495014198 NPW other 1 1 1 1.29644866130041 -0.0270227774789924 4.04505960262911e-14 13.036150221217 2.3251206775412 5.60665532208103 3.30055328009119e-08 -20.0926080689466 5.28278920645166 -3.80340901060528 0.000159075284332104 PP2D1 other 4.03818300130464e-10 1 0.000345534922892747 5.60665532208103 -3.80340901060528 9.15871860950312e-41 329.867759871106 49.4018481349053 6.67723521132877 6.11961742939722e-11 -1042.83602620547 109.994610121829 -9.48079205926943 8.2131744859033e-20 COA3 other 1.34541576373601e-36 1.2642539486151e-15 7.09018875369962e-07 6.67723521132877 -9.48079205926943 1.77539951837493e-07 10.6755133980483 1.93237379093929 5.52455919662374 5.18898651893822e-08 -1.01699032141936 5.43806197174383 -0.18701337474704 0.851721847637133 NPB other 0.0012619539776609 1 0.000538616800665787 5.52455919662374 -0.18701337474704 0.043901212340366 9.17729109946401 4.43003802197526 2.071605492761 0.0387764946278911 -4.52284236393452 8.80660021131111 -0.513574166580813 0.607759809500222 ST6GALNAC3 other 1 1 1 2.071605492761 -0.513574166580813 1.18771895806418e-06 490.305058120922 392.645684203554 1.24872137361056 0.212315180879399 -3041.56167524128 730.527700879951 -4.16351313109358 3.65435292668224e-05 PTP4A2 other 0.00787457669196553 0.425074332431679 1 1.24872137361056 -4.16351313109358 3.27327660048609e-16 11202.4991014655 1417.08402935564 7.90531744723666 1.54593902504117e-14 -8806.46542393072 3999.96974727626 -2.20163300733147 0.0281189594875574 ACTG1 other 3.51288044764167e-12 1 1.95916852643468e-10 7.90531744723666 -2.20163300733147 0.00248185334486504 90.5067206880665 27.9174409019847 3.24194187446573 0.0012598812711576 -67.4026689681881 89.1752053393142 -0.755845402449246 0.450069048837282 TMPRSS2 other 1 1 1 3.24194187446573 -0.755845402449246 5.68655024238121e-06 168.995638532672 53.6010575759719 3.15284149558327 0.00170655039822231 -250.58320571312 112.599206924416 -2.22544378914966 0.0264628793792491 DENND5A other 0.0353021039047026 1 1 3.15284149558327 -2.22544378914966 1.04088859770611e-21 219.509044845249 28.0099723369933 7.83681762353401 2.45941547009171e-14 -250.632939655846 61.6620766883134 -4.06462047852741 5.52355647074777e-05 DIABLO other 1.27550488762906e-17 0.635319465265408 3.10402826480275e-10 7.83681762353401 -4.06462047852741 2.25676535900945e-43 95.541540003224 7.05134418912773 13.5494080902386 3.40490013842152e-36 -65.1506913185325 18.0055033787122 -3.61837655677874 0.000324415867333441 VPS33B other 3.35129655812904e-39 1 5.10360481748001e-32 13.5494080902386 -3.61837655677874 5.93286633135473e-14 167.467800723339 24.2921426483634 6.89390817218101 1.52857867355942e-11 0.437808381522675 49.6514267910177 0.00881763948829519 0.992967907473352 TBX1 other 5.88658997397017e-10 1 1.80418140840218e-07 6.89390817218101 0.00881763948829519 0.670143247056958 5.58070780428998 10.9425871216444 0.509998937385781 0.610269853057573 -12.5849812572637 27.1617297182993 -0.463335044851176 0.643319215692216 ADAP2 other 1 1 1 0.509998937385781 -0.463335044851176 3.58898021155331e-25 381.006732424943 47.9520271708348 7.94558134252722 1.13225244731646e-14 -328.643156735586 99.8832468951411 -3.29027306331561 0.00106621205118077 UQCR10 other 4.64701157791922e-21 1 1.43999866249707e-10 7.94558134252722 -3.29027306331561 1.17811821979333e-26 1163.68283558595 115.410307720548 10.083006089921 5.52450632127917e-22 -2122.8906823621 714.69980881707 -2.97032496185466 0.00311021847561191 EIF3C other 1.55629416834699e-22 1 7.7276794422053e-18 10.083006089921 -2.97032496185466 0.0359484620988127 -73.886996966137 28.6394926596601 -2.57989894737939 0.0101474998643481 -67.6785202953366 56.5636912327765 -1.19650112678855 0.232029047995759 CLDN5 other 1 1 1 -2.57989894737939 -1.19650112678855 4.2690328038781e-47 658.256202885205 52.6786240619633 12.4956984850426 1.2071671424897e-31 -353.614412143689 108.15497138898 -3.26951602503701 0.00114607726114739 NIPSNAP1 other 6.40824514190142e-43 1 1.78527948702801e-27 12.4956984850426 -3.26951602503701 0.76847188113969 4.17998126236163 6.66145256629536 0.627487957132786 0.530604663965649 17.9140372670808 54.1338158490486 0.330921384094441 0.740832235745662 CNTN2 other 1 1 1 0.627487957132786 0.330921384094441 4.296708845816e-39 231.570481105522 18.2070216946601 12.7187458217528 2.50184340988779e-32 -149.701997330537 59.3837423491026 -2.52092561715756 0.0120127453035815 LRTOMT other 6.26674985162264e-35 1 3.70798211779469e-28 12.7187458217528 -2.52092561715756 0.026517868303943 20.0337476924128 7.81535575573351 2.56338269409113 0.010634949613245 -45.3796877582391 72.7413152458006 -0.623850250781091 0.532988884437755 KCNQ3 other 1 1 1 2.56338269409113 -0.623850250781091 0.000227751302922983 48.6238960377245 12.5662199202708 3.86941310483421 0.000122326167146994 16.3380547285554 24.2398123843261 0.674017375609718 0.500586558747964 ADRA2C other 1 1 1 3.86941310483421 0.674017375609718 3.63530867455837e-13 195.004851993201 28.0343156079155 6.95593410306553 1.03814369451486e-11 -117.935226116423 91.9956266113162 -1.28196557228424 0.200416268317904 NR2C2AP essential 3.49607635232279e-09 1 1.23165367917243e-07 6.95593410306553 -1.28196557228424 0.332511958408281 3.17373584213928 3.59923028254028 0.881781823612383 0.378302992414169 -4.46285889244993 6.73169569622862 -0.662962066890547 0.507649172904376 C1QTNF12 other 1 1 1 0.881781823612383 -0.662962066890547 7.06789702794541e-32 404.89275176262 35.6867589925466 11.3457417594908 6.66915178586242e-27 -55.752359568732 76.2724392358585 -0.730963374546448 0.465119151763854 CRELD2 other 9.8392194526028e-28 1 9.65493104039302e-23 11.3457417594908 -0.730963374546448 1.01928713221737e-17 70.6360311423779 12.0710340409878 5.85169678939931 8.60907511220581e-09 -131.149129083564 29.822133046653 -4.39771121932819 1.32693094908084e-05 SCFD2 other 1.14211123164956e-13 0.159072482175811 9.23839850290805e-05 5.85169678939931 -4.39771121932819 2.94200675168893e-06 128.746658304104 38.2819345972564 3.36311786900473 0.000824712826708654 -175.239095376849 74.0959534498511 -2.36502922518505 0.0183773237904779 UBE2F other 0.0188104452492334 1 1 3.36311786900473 -2.36502922518505 0.550435946384101 2.879986138417 6.30319407577151 0.456909005782832 0.647917840601077 -11.9913078001175 17.7512110446765 -0.675520547298865 0.499630566785531 KCNJ12 other 1 1 1 0.456909005782832 -0.675520547298865 3.31489929864347e-23 287.416257189889 27.5008850809678 10.4511638932231 1.96564420556145e-23 -313.471434612425 128.835943667357 -2.43310543385144 0.0152893042075813 PPP1R2 essential 4.16649692846497e-19 1 2.78649722580392e-19 10.4511638932231 -2.43310543385144 0.278132339297449 3.56345656611477 2.81562491865285 1.26560059278767 0.207158493209916 -4.16796955721881 7.022248269522 -0.593537767001011 0.553505646633031 GOLGA6L4 other 1 1 1 1.26560059278767 -0.593537767001011 1.43630543018926e-15 106.294512394298 14.3426853115804 7.4110607661785 4.85365121613684e-13 -105.950133833221 65.9080630712029 -1.60754434125547 0.10851843426518 PGP other 1.51070605147307e-11 1 5.94232518391633e-09 7.4110607661785 -1.60754434125547 3.53359723056913e-16 83.7166739952553 18.8143958936278 4.4496073362424 1.04387242123828e-05 -154.19537242093 35.339541991708 -4.3632532775074 1.53361488391566e-05 C22orf46 other 3.78872295061622e-12 0.18309828099069 0.0939301495989972 4.4496073362424 -4.3632532775074 9.69055767489294e-18 76.683197605824 16.3876141602629 4.67933872837738 3.63371300478666e-06 -230.386369696795 37.2279607249292 -6.18853048113698 1.19301839975603e-09 SNRNP35 essential 1.08669913766249e-13 1.66819762837885e-05 0.0337608275274729 4.67933872837738 -6.18853048113698 2.6262232273016e-18 219.779783017356 23.996233636865 9.15892828613369 1.0708599534123e-18 -48.4484998384633 83.1336568557272 -0.582778403728135 0.56028485844463 CMSS1 other 2.9875915433783e-14 1 1.45176483884106e-14 9.15892828613369 -0.582778403728135 0.964333618199039 3.66720872817586 19.85190076194 0.184728342749255 0.853516570087117 -3.37386774262357 37.6098968683655 -0.0897069129019976 0.928555830157706 PCDH9 other 1 1 1 0.184728342749255 -0.0897069129019976 1.78998252743719e-13 53.4586346864128 26.215051137466 2.03923442323601 0.0419093866580104 -306.364916024269 51.5146630599599 -5.94714005345777 4.88442379820723e-09 ACOT1 other 1.74362197997656e-09 6.73610886010759e-05 1 2.03923442323601 -5.94714005345777 0.00319800942476685 -26.5939756667042 32.7251939106063 -0.812645319668682 0.416777578625795 -188.367122924632 59.6679563514417 -3.15692265066291 0.00168294366829631 OAF other 1 1 1 -0.812645319668682 -3.15692265066291 0.0497956846050742 116.827220369074 53.0971608795345 2.20025361872226 0.0282108599159082 282.157315874631 176.315850515955 1.60029467032573 0.110116995180627 ALDH1A3 other 1 1 1 2.20025361872226 1.60029467032573 0.487926257181596 1.72707386944407 1.45501031426132 1.18698393579489 0.235796470337966 -4.29400743620816 17.2763411856666 -0.248548427590137 0.803811954806306 HIST2H2AC other 1 1 1 1.18698393579489 -0.248548427590137 0.0412803232914573 -15.9235433949957 6.53002393841249 -2.43851225434663 0.0150678988906538 -25.6460953703083 19.1550882781489 -1.33886594506401 0.181175579454584 POU6F1 other 1 1 1 -2.43851225434663 -1.33886594506401 5.55099813475885e-54 220.495403565665 13.476800133837 16.361109564284 4.39640087084371e-49 -104.604600273276 43.3729540140081 -2.41174719710103 0.0162119952208792 TM2D3 other 8.45250485979729e-50 1 6.7313293733488e-45 16.361109564284 -2.41174719710103 6.43815738523425e-10 96.0848950934411 35.449151055858 2.71049918634266 0.00692953301744467 -286.500748066814 70.7920202300895 -4.04707687583464 5.93513578108677e-05 TSSC4 other 5.32564378906577e-06 0.680674991375877 1 2.71049918634266 -4.04707687583464 7.73683444618368e-05 1290.02849065369 477.641057137649 2.70083250042284 0.0071337937291727 -2229.86292316347 965.596272159177 -2.30931185989073 0.0213027549758517 TACSTD2 other 0.426918524740416 1 1 2.70083250042284 -2.30931185989073 0.442931263662901 -0.683900163165402 0.543464980797949 -1.25840704981811 0.208785386733045 -1.06350066285946 1.76399647379739 -0.602892737404426 0.546831759373447 CLECL1 other 1 1 1 -1.25840704981811 -0.602892737404426 0.0302268771478636 11.0095581226791 7.07209195869688 1.55676116585845 0.120124104284514 -49.6824465014726 28.565382836344 -1.73925365489103 0.0825707441025843 PRKD1 other 1 1 1 1.55676116585845 -1.73925365489103 0.000102129311388727 22.657359572345 7.67729747508367 2.95121553461729 0.00330247815481411 -33.0041148613886 17.5339245571655 -1.88230049432379 0.0603316861264272 CCSER1 other 0.554460031529401 1 1 2.95121553461729 -1.88230049432379 2.66862185826442e-07 49.83025938738 10.7503275283898 4.6352317411527 4.47564948997051e-06 -81.6336527154614 35.4198644698191 -2.3047420970518 0.0215594540197444 ZDHHC23 other 0.00186883588734257 1 0.0413191960914077 4.6352317411527 -2.3047420970518 0.444540905580697 1.33648097858524 3.5969277717824 0.371561805902755 0.710364069576349 -8.38003466300123 8.12509058931139 -1.03137738230577 0.302823039399941 MROH7 other 1 1 1 0.371561805902755 -1.03137738230577 0.242813597120939 93.6897496039515 59.2676590675118 1.58079045263505 0.114511481174344 321.635914162135 651.174376874719 0.493932079615619 0.621554993373814 S100A7A other 1 1 1 1.58079045263505 0.493932079615619 0.0217430688826468 104.195907489113 103.373326267904 1.00795738369758 0.313920582088598 -537.812442516712 263.774679959473 -2.0389085207092 0.0419393756552696 SLIT3 other 1 1 1 1.00795738369758 -2.0389085207092 1.78845014405085e-07 18.1923523523135 58.3995840781926 0.311515101339683 0.75552819021392 684.45624042193 128.682351696957 5.31895968169593 1.52587760838512e-07 EFNA5 other 0.00127087267236253 0.00200332471204882 1 0.311515101339683 5.31895968169593 1.40485032216637e-13 400.199589268163 74.418062694125 5.37772114430167 1.12818605880389e-07 -324.4609241589 152.650596900206 -2.12551362882002 0.0340004179046876 PKP3 other 1.37450555520757e-09 1 0.00114815495204472 5.37772114430167 -2.12551362882002 0.00137542909489254 -50.471976536853 86.8948996302549 -0.580839344445019 0.561589280515031 -687.164920465211 194.838999788666 -3.52683457218807 0.000456072502166134 CSF1 other 1 1 1 -0.580839344445019 -3.52683457218807 0.00167512528328521 9.21325764660029 2.5678620044642 3.5879099541109 0.000363938205795471 -3.37691282551731 10.9515504358278 -0.308350205325248 0.757935889404783 ACTRT3 other 1 1 1 3.5879099541109 -0.308350205325248 8.78530478673242e-10 17.8331993015228 15.8431807883828 1.12560725902965 0.260831811862509 -171.065603658364 32.7367303633126 -5.22549447546763 2.48528385605655e-07 PLA2G6 other 7.20922110799262e-06 0.00323310576834397 1 1.12560725902965 -5.22549447546763 0.000272169646631494 194.374370874787 48.905285443988 3.97450641807228 8.02041281028914e-05 140.561402503147 96.7944886343505 1.45216328415278 0.147042395613877 MAML2 other 1 1 0.668661815993806 3.97450641807228 1.45216328415278 3.24161588292693e-42 165.90956766971 10.9978882253233 15.0855840931074 6.46794552494557e-43 299.048025098648 81.1265314337118 3.6861926648867 0.000251536694195026 SS18L1 other 4.79240492131917e-38 1 9.82610284149731e-39 15.0855840931074 3.6861926648867 0.498377624907769 -19.5153359878827 30.5055165457248 -0.639731373131517 0.52261656861743 -109.381367693221 95.7407507353323 -1.14247451428073 0.253759408796402 KCND2 other 1 1 1 -0.639731373131517 -1.14247451428073 4.03768245129816e-17 142.688381809704 15.83190823765 9.01270899678257 4.0195559618886e-18 147.325693430023 109.912782736132 1.34038725762869 0.180715101381122 TOP1MT other 4.45315997553674e-13 1 5.41072428029825e-14 9.01270899678257 1.34038725762869 4.27720470230767e-17 1155.90727751794 134.59337995351 8.58814362130743 9.30433634037945e-17 -845.820779706306 503.859657725328 -1.67868327368132 0.0937870066639651 COPB2 essential 4.71347958194305e-13 1 1.22733500665945e-12 8.58814362130743 -1.67868327368132 3.0897793945178e-14 95.7391344846335 22.960003634773 4.1698222703953 3.56183518700086e-05 -184.51797146406 46.715711435178 -3.94980544650582 8.88094290146497e-05 THAP7 other 3.09843077682245e-10 1 0.306674009600774 4.1698222703953 -3.94980544650582 4.21041805809167e-10 204.470599957622 30.6267019614169 6.6762199931031 6.09932105692946e-11 93.7516158882144 67.9390929431868 1.37993623150979 0.168177337441376 KNTC1 other 3.51906741295302e-06 1 7.06728330866416e-07 6.6762199931031 1.37993623150979 0.442369538539975 0.343973904252578 1.34605437299992 0.255542354864886 0.798402265901774 -3.1644288584728 3.0092898483366 -1.05155336240607 0.293478356709045 CCR10 other 1 1 1 0.255542354864886 -1.05155336240607 0.0405824097772958 75.2709701326451 30.1334459375173 2.49792109036325 0.0127854807286024 43.650640859753 50.8048211390247 0.859183043678184 0.390616585310471 NCMAP other 1 1 1 2.49792109036325 0.859183043678184 5.94458787402709e-15 23.1773423924635 9.78246156780593 2.36927507783318 0.0181743867901923 -115.51661770959 19.9191808093106 -5.79926548262442 1.13573717520752e-08 WDR27 other 6.12708672175972e-11 0.000154914550698306 1 2.36927507783318 -5.79926548262442 5.56994617098508e-16 168.027386509708 29.1988246185315 5.7545941901739 1.45815934468028e-08 -156.929028256997 59.5997598406341 -2.63304799678077 0.00870509315319121 TXNRD2 other 5.93700562365299e-12 1 0.000155133572680535 5.7545941901739 -2.63304799678077 0.593152690387324 -1.95582995871961 20.1577935964783 -0.0970259939094382 0.922742087681212 -42.0856194547343 46.0545334129192 -0.913821427250167 0.361222324844458 POU3F2 other 1 1 1 -0.0970259939094382 -0.913821427250167 7.94635552322389e-05 80.9401350698676 18.743660916843 4.31826714263354 1.87876697955151e-05 -33.6959057965242 139.420507982882 -0.241685432681549 0.809117751923401 PTP4A3 other 0.437685262219172 1 0.165444220219306 4.31826714263354 -0.241685432681549 0.0408567321919053 -1.47514132585288 3.12495801521924 -0.472051566347008 0.637081739683375 -22.7433653533746 8.98425092891502 -2.53147040675112 0.0116426961223846 TMEM255B other 1 1 1 -0.472051566347008 -2.53147040675112 0.0307939221371036 -75.6184260041957 28.6496388831194 -2.63941986538444 0.00855999218962505 -5.76780002302841 98.740108900686 -0.0584139524175503 0.953441871486107 PROS1 other 1 1 1 -2.63941986538444 -0.0584139524175503 1.28614704353227e-24 125.715014803934 13.1810239445549 9.53757578567081 5.18103483797974e-20 -99.3636786573055 33.3978746561207 -2.97514975669553 0.00306124523021084 HDDC3 other 1.65269895093896e-20 1 7.12651341964114e-16 9.53757578567081 -2.97514975669553 1.17461545633921e-35 58.5553516290636 7.70352898007295 7.60110746393389 1.28450952250237e-13 -77.7199963065737 16.857065958755 -4.61052928764324 5.00505600213124e-06 ZFP1 other 1.6839287182079e-31 0.0615021281541887 1.59561772885244e-09 7.60110746393389 -4.61052928764324 1.21343860089592e-06 82.687322502378 23.7537690214826 3.48101905123337 0.000539619795250546 -83.4037919909511 47.1861283102616 -1.76754895935832 0.077696885745993 DUSP8 other 0.0080353904151328 1 1 3.48101905123337 -1.76754895935832 0.172671092437352 130.996222398332 82.9486292292682 1.57924517397703 0.114867569084287 -175.4635286801 248.515527393468 -0.706046541720885 0.480464817529363 SOCS3 other 1 1 1 1.57924517397703 -0.706046541720885 0.039195647990694 -296.413321814275 356.173379732304 -0.832216383035295 0.405666650161499 -1969.71509018487 772.991537324275 -2.54817161000634 0.0111137242307743 SLITRK6 other 1 1 1 -0.832216383035295 -2.54817161000634 0.627595340798276 -3.9537737973063 4.68715691029706 -0.843533483724512 0.399310691312822 -11.3851719637604 17.4698543853934 -0.651703884451358 0.514874710314279 LPAR5 other 1 1 1 -0.843533483724512 -0.651703884451358 2.78756409997015e-16 515.387387818989 66.7032265420646 7.72657357877543 5.68303583433151e-14 1483.46413750117 279.63704830146 5.30496279556611 1.66677610065798e-07 XPOT other 2.99830394592789e-12 0.00218381004708209 7.11857068608365e-10 7.72657357877543 5.30496279556611 0.000280171065191868 28.2192725543481 32.6999117682591 0.862977024352088 0.388530388455286 -265.979687988211 77.7671166284394 -3.42020765999369 0.000672696273402446 TMEM173 other 1 1 1 0.862977024352088 -3.42020765999369 0.000422840883545659 420.396802481527 119.186132570897 3.52722916176056 0.000455678275565683 -126.449962731119 241.527133789471 -0.523543507295293 0.600810863297901 PDE4B other 1 1 1 3.52722916176056 -0.523543507295293 0.0139010873086425 12.7452935603798 6.28932745321779 2.02649546476689 0.0432013846879539 38.2715425367685 13.7765878076315 2.77801318230398 0.00565807684603583 FAM19A3 other 1 1 1 2.02649546476689 2.77801318230398 0.338544654072787 14.2935039501577 16.1989526347423 0.882372105928752 0.377971893008544 -24.4491171309331 33.6723067654699 -0.72608975979053 0.468101268784426 C14orf180 other 1 1 1 0.882372105928752 -0.72608975979053 1.91718665117271e-14 193.377141327734 24.9599613433222 7.74749362260013 4.68374842970484e-14 -29.4812806359233 129.602774236985 -0.227474147906859 0.820141325988654 SNN other 1.93770054834025e-10 1 5.87950940380849e-10 7.74749362260013 -0.227474147906859 0.0423143057290168 203.695472506021 219.753689844625 0.926926290293654 0.354389911890081 -1339.53649322436 660.217221735271 -2.02893297709444 0.0429682552875016 NELL2 other 1 1 1 0.926926290293654 -2.02893297709444 2.39964157608068e-27 15.9440584231423 4.26694941414579 3.73664106967955 0.000206243280306188 -63.3733170544714 7.58930282043541 -8.35034766089826 5.69085776464717e-16 KRBA2 other 3.19656254349707e-23 8.60457694014652e-12 1 3.73664106967955 -8.35034766089826 0.000300999010757572 40.5461120007994 11.0084036833801 3.68319632591363 0.000253648637068722 -16.7615724091774 37.4812311019373 -0.447199089154545 0.654911636081047 ZNF93 other 1 1 1 3.68319632591363 -0.447199089154545 1.62163268389686e-19 1723.22950684463 181.766615488103 9.48045108402993 7.99945325466044e-20 -10.2195193502197 533.061401343211 -0.0191713737375628 0.984711488378156 SEPT9 other 1.90136432186907e-15 1 1.09776497013705e-15 9.48045108402993 -0.0191713737375628 0.028184068772236 43.6526668587318 23.2129092983339 1.88053407255871 0.0605683342029733 -11.2842643165297 46.5659602407308 -0.242328607811237 0.808616710629891 CDCA2 other 1 1 1 1.88053407255871 -0.242328607811237 1.67987442342022e-05 8.37739491771416 3.21320961642452 2.60717348625269 0.00938122389794225 -21.9074798416047 8.06047113179353 -2.71789073906528 0.00678061497972746 OR7E14P other 0.100137314380079 1 1 2.60717348625269 -2.71789073906528 7.15917731130751e-14 -23.4063743145484 37.9296183280064 -0.617100180448311 0.537425894805716 -433.172298799808 60.8646439609753 -7.116977453734 3.48663139519619e-12 ZBTB40 other 7.08400594953878e-10 5.09187648954451e-08 1 -0.617100180448311 -7.116977453734 0.650613000795562 15.3010629923471 64.9821257428173 0.235465719495001 0.813943499967058 -703.010833988111 771.577606219753 -0.911134315357367 0.362662779497819 HIST2H2BE other 1 1 1 0.235465719495001 -0.911134315357367 0.071314620817507 34.1205711670747 28.9693029805178 1.17781816117637 0.239386003526704 297.799057682639 131.757750904941 2.26020143511323 0.0242047466712445 CLDN6 other 1 1 1 1.17781816117637 2.26020143511323 4.41675103990978e-55 140.598304445475 14.7399391948634 9.53859460251173 4.84185969374255e-20 -272.206717777168 30.3712045980321 -8.96265793141459 5.0861080232396e-18 EIF4ENIF1 other 6.73554533586242e-51 7.777676389138e-14 6.66385149649787e-16 9.53859460251173 -8.96265793141459 0.00710267746280848 -3.39272989767736 21.5209077007735 -0.157648085519897 0.874796875381363 -151.819983297163 49.9840474071558 -3.03736874408109 0.00250946690308811 LRRC26 other 1 1 1 -0.157648085519897 -3.03736874408109 5.45990278778768e-39 25.5428103370364 15.2989316473562 1.66958130971521 0.0956099112869809 -312.831398805982 26.5200135119785 -11.7960497518104 1.3578909377301e-28 SERINC4 other 7.96108425487321e-35 2.12224774657838e-24 1 1.66958130971521 -11.7960497518104 4.48415590242667e-06 5.58126838964802 6.85597050596773 0.814074154022372 0.415966012811303 -62.1437343215026 14.2138228465024 -4.37206337750258 1.48041795159369e-05 RNLS other 0.0281201416641177 0.176924749394962 1 0.814074154022372 -4.37206337750258 2.81547044237403e-07 134.251651004913 26.5070524297548 5.06475215834305 5.64736459317011e-07 -164.03157124558 158.244343357752 -1.0365714676748 0.300406536936095 APOBR other 0.00196801383921945 1 0.0055140867887713 5.06475215834305 -1.0365714676748 6.55816152625089e-08 1.53720974490977 18.3551462877174 0.0837481609143274 0.933287416567963 -323.165411981395 56.9078415945281 -5.67875011468487 2.20900693415086e-08 FAM110C other 0.00048071323987419 0.00029856937721983 1 0.0837481609143274 -5.67875011468487 3.64828129499287e-13 308.666386708191 91.1262944263848 3.38723733529561 0.000758646407727517 -1150.37590709306 226.268836693748 -5.08411111270297 5.13718261808063e-07 ATL3 other 3.50709280887664e-09 0.0066074442833753 1 3.38723733529561 -5.08411111270297 1.62688593763568e-21 144.571702920144 16.2464292369798 8.89867556811024 8.61701323654594e-18 -108.346641158134 43.6652710289317 -2.48130009513385 0.0133948003641656 NDUFA12 other 1.98431277813424e-17 1 1.15528296462371e-13 8.89867556811024 -2.48130009513385 7.19320717402478e-21 15.7225332180557 2.45086174265593 6.41510410171797 3.07829482691749e-10 -17.7124175850114 4.95605503551517 -3.57389444993729 0.000383207744615283 TCTE3 other 8.67428853115648e-17 1 3.49448028751673e-06 6.41510410171797 -3.57389444993729 6.62048908449599e-21 322.489347143031 36.8390235369575 8.75401452537159 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-459.736312089853 107.610578166206 -4.27222230308794 2.28881148999483e-05 ZBTB7C other 0.671876520046602 0.270011091474691 1 -1.73359492717928 -4.27222230308794 0.373190014487826 -12.3703699793674 9.10382348281541 -1.35881039463452 0.17477082903189 -3.54239683701179 20.6538157759454 -0.171512948282296 0.863884346719512 PRR16 other 1 1 1 -1.35881039463452 -0.171512948282296 9.01752046327494e-15 845.155637079303 107.459801469858 7.86485388507226 2.03585527130108e-14 85.8892294530675 306.527144370125 0.280201055699518 0.779430961965735 TMED9 other 9.2294321941619e-11 1 2.57230313528892e-10 7.86485388507226 0.280201055699518 0.0153643617009136 -0.365971038156264 1.47683479684718 -0.247807702620196 0.804377045853599 -11.662560436723 4.18360672087249 -2.78768087318943 0.00549500192520901 DRD1 other 1 1 1 -0.247807702620196 -2.78768087318943 3.60390295251208e-34 103.594150324629 8.4506045662278 12.258785689563 1.18475711955628e-30 -56.5593662458099 41.7351881825064 -1.35519614763633 0.17592166745127 TMEM186 other 5.11141555754788e-30 1 1.74585809137813e-26 12.258785689563 -1.35519614763633 2.13379156844308e-10 80.9148651517098 22.2821738006511 3.63137213970324 0.000308422291104087 -115.059213565711 47.558762937966 -2.41930627413059 0.0158752851966399 SDR42E1 other 1.81500310811768e-06 1 1 3.63137213970324 -2.41930627413059 1.55347834407938e-07 63.6252118487491 20.23060796293 3.14499751887507 0.00175143978166335 -214.135427274734 62.9404058226286 -3.40219330453931 0.00071754899854154 RBM33 other 0.00110949423334149 1 1 3.14499751887507 -3.40219330453931 1.44514240515378e-19 211.715945421577 34.4640325074731 6.14309847159264 1.61005548326737e-09 -340.293811699141 75.0341507549465 -4.53518575575679 7.15166102594314e-06 BTBD6 other 1.69674169789106e-15 0.0871215346180393 1.77589119804391e-05 6.14309847159264 -4.53518575575679 0.000237625372548731 306.010640635688 109.319191252915 2.79923988760326 0.00530550411978665 -857.655659125896 351.852987947608 -2.43753979219754 0.0151092280787013 H1FX other 1 1 1 2.79923988760326 -2.43753979219754 3.00033319252389e-15 -51.9367264694901 15.6690759338925 -3.31460047092821 0.000980507803026549 -313.644365491652 37.235391132847 -8.42328644736518 3.45339880802164e-16 RBM43 other 3.12244675345961e-11 5.22740977570236e-12 1 -3.31460047092821 -8.42328644736518 2.93596621380239e-18 581.941465568481 64.0199746963726 9.08999836892242 1.84084284583456e-18 -24.1174167857974 184.085659173079 -0.131011926155106 0.895814307501111 SUMO3 other 3.33496402225813e-14 1 2.48808319042998e-14 9.08999836892242 -0.131011926155106 1.1175951813218e-11 17.5064908732532 6.59850430876967 2.65309986234098 0.00821174343625417 -112.80027049093 20.0836108986375 -5.61653335449664 3.12991717552398e-08 IMMP2L other 1.01019428439678e-07 0.000421099056794997 1 2.65309986234098 -5.61653335449664 0.188331129108233 37.9466387266108 37.4726571296017 1.01264873199063 0.311699828925697 -82.22586995174 81.6306769925101 -1.00729129024968 0.31426419845173 JAG2 other 1 1 1 1.01264873199063 -1.00729129024968 0.619002717580476 8.59598302984312 20.3995420204802 0.421381177146681 0.673646958683875 48.3930146555344 49.453979679214 0.978546417688492 0.328248912168064 FMNL1 other 1 1 1 0.421381177146681 0.978546417688492 2.23900332836957e-14 17.9233014890608 3.82202796884879 4.68947418363852 3.48128352170544e-06 -38.9731956014742 8.12789625703 -4.79499176281506 2.11168088236966e-06 NUTM2A other 2.25579585333235e-10 0.0264150161575621 0.0323724554683389 4.68947418363852 -4.79499176281506 4.31516019850668e-09 50.7131821001275 12.4657819589416 4.06819101017176 5.44209312830709e-05 -129.781252001989 35.9895569813602 -3.60608084365156 0.000339568992789468 PTRHD1 other 3.41329171701879e-05 1 0.460999708898893 4.06819101017176 -3.60608084365156 0.0798467144757693 -7.98325033109561 7.80436318618134 -1.02292142749469 0.306829955066371 -40.4483899620955 18.1257808033375 -2.23153917621291 0.02607919813064 LCN12 other 1 1 1 -1.02292142749469 -2.23153917621291 0.213635484851222 9.21405268668382 16.6660114193119 0.552864896996708 0.580587282675718 -113.043624293521 73.5933456246322 -1.53605768747228 0.125116501855646 WT1 ts 1 1 1 0.552864896996708 -1.53605768747228 8.05252507048507e-26 108.916657633898 17.6491312571143 6.17121919754517 1.33436974999794e-09 -159.0733767945 39.5044394039755 -4.02672153293465 6.46901662732373e-05 ZFP90 other 1.05278712771522e-21 0.739759053717388 1.47821480904772e-05 6.17121919754517 -4.02672153293465 1.28448729371625e-12 18.8772461730541 5.20666689563921 3.62559129504991 0.000315442207868425 -45.4913480079133 10.8183219848483 -4.20502810617271 3.05307576496298e-05 FAM227A other 1.20895944084574e-08 0.356935087681822 1 3.62559129504991 -4.20502810617271 0.766758152120383 149.636671153745 757.380252333663 0.197571392563616 0.843453680398017 -1215.73737796698 2145.26873247582 -0.566706333599483 0.571145746265487 MUC6 other 1 1 1 0.197571392563616 -0.566706333599483 2.57436835384104e-08 75.5144904249509 17.4861422233996 4.31853346839985 1.86992602541344e-05 -109.596477199888 41.2860428601999 -2.65456482644745 0.00817576061441969 NOC4L essential 0.000194364810714999 1 0.164703084318416 4.31853346839985 -2.65456482644745 1.06133129528329e-06 142.265483403205 29.9768464192508 4.7458455573847 2.66122961222074e-06 29.1514445988672 60.0594456508022 0.485376517931245 0.62760578309401 USP18 other 0.00706528243270087 1 0.024943705155345 4.7458455573847 0.485376517931245 5.98956044229072e-30 252.542727954743 35.0003079155783 7.21544303449796 1.8074275770958e-12 -364.795252441697 68.1239492270626 -5.3548752910053 1.26330376942027e-07 NDUFA6 other 8.19012494878834e-26 0.00166415005545732 2.18626439725508e-08 7.21544303449796 -5.3548752910053 0.000234555092035123 -83.6835764529246 23.0225253008642 -3.63485653112882 0.000304530349518461 -154.273209404146 44.4719714461437 -3.46899866112239 0.000563796522136498 SORCS2 other 1 1 1 -3.63485653112882 -3.46899866112239 2.00916050622931e-06 14.297810148977 10.9745112798286 1.30281975975155 0.19320963719541 -108.541724399743 26.6109184162255 -4.07884172586698 5.23181275626052e-05 TMEM121 other 0.0130655707720092 0.6028617839039 1 1.30281975975155 -4.07884172586698 5.55328248392101e-10 20.6618246599858 8.00926564991649 2.57974021128906 0.0101531013754007 -81.6239761326309 17.8649563136482 -4.56894350591125 6.09159520467805e-06 TMEM106A other 4.61422241588997e-06 0.0744941177580078 1 2.57974021128906 -4.56894350591125 6.74665351498972e-12 222.211974159005 40.4406147147694 5.49477241447198 6.06033851081513e-08 -195.998190591015 84.3279489891916 -2.32423760971746 0.020486300063672 SIVA1 other 6.1684653087551e-08 1 0.000627002622328933 5.49477241447198 -2.32423760971746 1.68649706044676e-11 267.416541999619 44.104347332011 6.06326945474437 2.49088903198013e-09 -193.513006031597 101.117550202201 -1.9137430213117 0.0561755465645474 BRI3BP other 1.51025811763007e-07 1 2.72727440111505e-05 6.06326945474437 -1.9137430213117 0.221849308712587 -12.9128923280792 49.9576312130706 -0.258476873593252 0.796136838472174 -237.353900015291 137.681531811251 -1.72393418995862 0.0852888985925199 ROBO2 other 1 1 1 -0.258476873593252 -1.72393418995862 2.79687601199335e-19 341.879696986516 45.6804068060011 7.48416489455613 3.01812169355899e-13 -405.612703003202 117.216497138846 -3.46037215668324 0.000582912156163377 AP3M1 other 3.25975899197826e-15 1 3.71711867778725e-09 7.48416489455613 -3.46037215668324 0.130914936968766 3.53091165844223 4.28849353834195 0.823345453799466 0.410694154015595 85.367437867483 45.9894698308597 1.85623879078076 0.0639926865452603 CA13 other 1 1 1 0.823345453799466 1.85623879078076 9.96014870923e-26 67.1540742702425 7.96192260558116 8.43440430118836 2.98812643779469e-16 -156.625916823836 31.2349645318025 -5.01444196180739 7.20162556120675e-07 UBOX5 other 1.29989900804161e-21 0.00920943876767119 3.906377692129e-12 8.43440430118836 -5.01444196180739 2.05602283325007e-06 95.6905284599184 29.0910019062615 3.28935142104275 0.00106939429020651 -121.428224050991 59.9944021831577 -2.02399256651114 0.0434609624669585 MAFF other 0.0133538683019592 1 1 3.28935142104275 -2.02399256651114 2.8996878324671e-23 107.551508241074 24.5215312874507 4.38600293677888 1.39866889889323e-05 -389.234677391643 53.3987568130089 -7.28920860001779 1.16940882247153e-12 BRF1 essential 3.64780729324361e-19 1.71704297403495e-08 0.124551465446442 4.38600293677888 -7.28920860001779 0.124380738999367 2.16726688544029 2.65597983741673 0.815995232685287 0.414875768821132 23.0941626886862 11.5624088094201 1.99734874188768 0.0463068828995639 LRRC14B other 1 1 1 0.815995232685287 1.99734874188768 8.01074588578833e-45 538.811353865903 38.9039039463226 13.8498016705296 1.39689704886387e-37 -1318.1523043882 242.288546207652 -5.44042351576325 8.04704093687535e-08 SEMA4B other 1.19544360853619e-40 0.00106880797723578 2.09981564385217e-33 13.8498016705296 -5.44042351576325 1.99500013191093e-54 635.034607777558 39.8406256543322 15.9393733744868 3.23219951369727e-47 -1358.04129398684 248.126081204679 -5.47319043364325 6.7560290616937e-08 CIB1 other 3.0395822009795e-50 0.000898957226948964 4.93686153722121e-43 15.9393733744868 -5.47319043364325 2.66182251453394e-06 30.9258656095162 13.4923937731093 2.29209628251083 0.0222860873536355 -123.339750780244 33.3831736685246 -3.69466821833464 0.000242739247349512 ANKS1B other 0.0170915623658224 1 1 2.29209628251083 -3.69466821833464 1.20549923262889e-09 118.335458997669 21.9024722198071 5.40283570777251 9.83094559664878e-08 -350.565881290733 135.560684164979 -2.58604390683135 0.00996767663363783 SLC24A3 other 9.82481874592546e-06 1 0.00100472263997751 5.40283570777251 -2.58604390683135 1.27703018461428e-21 33.6171409888661 4.17091547050216 8.05989505819899 4.92051052953914e-15 -46.435552451455 12.7943331890135 -3.6293843348811 0.000311054566435359 EFCAB10 other 1.56091399465403e-17 1 6.29480912043942e-11 8.05989505819899 -3.6293843348811 0.90593368341116 -1.05462232643123 4.49222316992354 -0.234766236346442 0.814478027876564 4.14948168458125 13.6322531560226 0.30438707652286 0.760948776758005 KRT76 other 1 1 1 -0.234766236346442 0.30438707652286 0.131323497062258 17.5058537745526 35.35927351307 0.495085221931436 0.620741348916129 -110.352038245519 70.6698449475149 -1.56151521667374 0.118988068604914 FLRT2 other 1 1 1 0.495085221931436 -1.56151521667374 4.07451035216725e-27 97.5140858164355 19.1027848618094 5.10470523129782 4.66673431319831e-07 -361.041612832062 47.6451139589327 -7.57772587433117 1.64105761009873e-13 INTS5 other 5.41543170906549e-23 2.43089863783924e-09 0.0045864664830113 5.10470523129782 -7.57772587433117 4.4872040407515e-11 180.32941644043 58.0799343632236 3.10484883320762 0.00200361689325268 -667.624141893139 128.577795564611 -5.19237508281634 2.94557800000136e-07 RPS27L other 3.93752154575944e-07 0.00382159289720177 1 3.10484883320762 -5.19237508281634 0.0115970376671432 122.748311338127 41.6851392533394 2.94465398309286 0.00337191500535781 128.113231960839 86.7298400030977 1.47715286868122 0.140215460628412 MANEAL other 1 1 1 2.94465398309286 1.47715286868122 0.00188407220330974 64.673046208365 29.1114769637561 2.22156527093707 0.0267303888054332 -102.434258253385 60.7041006105945 -1.68743556404009 0.0921024970777818 ADSSL1 other 1 1 1 2.22156527093707 -1.68743556404009 2.02483206097122e-12 113.034356891162 27.850867175533 4.05855789619585 5.66878422411647e-05 -186.014919659521 57.2308698537546 -3.25025497838589 0.00122498197880541 ANO9 other 1.88977576250444e-08 1 0.479352393991289 4.05855789619585 -3.25025497838589 1.56848111844665e-24 394.242072864303 44.6201497403708 8.83551658069867 1.41315435355998e-17 -284.455119489428 89.9667213226052 -3.16178154886206 0.00165644561887721 FAF1 other 2.01330236363812e-20 1 1.88769158548542e-13 8.83551658069867 -3.16178154886206 0.752927164896461 2.7569356782333 4.59377090015064 0.600146532806608 0.548658036052362 9.24567605793176 21.4274103506162 0.43148826230725 0.666284016661299 FAM43A other 1 1 1 0.600146532806608 0.43148826230725 2.21778776893794e-24 66.0014309513252 11.7019746696171 5.64019601945396 2.73798837372905e-08 -118.646399948693 21.7700469552291 -5.44998364921739 7.65885697647284e-08 NSMCE3 other 2.83987723812503e-20 0.0010181684464523 0.000287954237265084 5.64019601945396 -5.44998364921739 7.63544188516116e-37 472.951443577999 33.9154963594907 13.9449954842147 1.50683600703558e-37 35.0852899135589 231.703078849777 0.151423494619622 0.879702976745605 HSF1 essential 1.10064894774598e-32 1 2.26492520217519e-33 13.9449954842147 0.151423494619622 5.56947278272658e-24 81.9368612832982 17.2117103399006 4.76052987560161 2.48308720100918e-06 -213.876718368979 34.8151565621297 -6.14320713989331 1.57028889009569e-09 C6orf120 other 7.08325548507167e-20 2.19008191501646e-05 0.0233385366022853 4.76052987560161 -6.14320713989331 9.1223797286061e-16 81.2534158290812 27.6309968413814 2.94066176097536 0.00341471210964104 -430.165814538816 65.8250157284183 -6.53498992409815 1.46702394212121e-10 PURA other 9.65877565664814e-12 2.09036241512852e-06 1 2.94066176097536 -6.53498992409815 4.3827334709378e-13 199.513248298754 65.574397292069 3.04254795374055 0.00245992468481624 -657.192265314695 135.407297661794 -4.85344790615468 1.59047187631656e-06 INPP5J other 4.19471420503457e-09 0.0200113171478149 1 3.04254795374055 -4.85344790615468 0.521474568377504 -16.8300767231248 31.74692091179 -0.530132568443023 0.596235931613616 -81.1265167567918 71.4164224463235 -1.13596444596152 0.256470719509405 NPY2R other 1 1 1 -0.530132568443023 -1.13596444596152 4.61201971700707e-07 23.6949811003778 7.87483847997699 3.00894820390615 0.00274318607081673 -39.4577619986063 14.0791758426774 -2.80256191410013 0.00525094231957011 MFSD6L other 0.00316845754558386 1 1 3.00894820390615 -2.80256191410013 3.32456754353082e-08 32.0116299240876 6.06956861757963 5.27411945411912 1.96876618867673e-07 -5.51179643663472 14.3742308579595 -0.383449834018956 0.701544805193089 LRRC37B other 0.000249043354685894 1 0.00197723188328804 5.27411945411912 -0.383449834018956 2.24302515902021e-13 94.410092011249 17.4526773380977 5.40949048574686 9.51827904497364e-08 -154.488491184698 41.2070298525715 -3.74908096354965 0.000196670500246792 DDX51 essential 2.17663161431321e-09 1 0.000973815129091254 5.40949048574686 -3.74908096354965 9.77290447100794e-11 138.245166179756 66.0610677715216 2.09268743063449 0.0368449585064884 -611.864734394138 135.645982083657 -4.51074720382638 7.93682249813225e-06 SIGIRR other 8.42522094445595e-07 0.0964085828848125 1 2.09268743063449 -4.51074720382638 1.16188778230084e-07 823.000494542345 343.656151023769 2.39483708378443 0.0169688215771129 -2238.33258099419 704.145857461852 -3.17879109459286 0.00156395272906823 IFITM2 other 0.000836559203256605 1 1 2.39483708378443 -3.17879109459286 0.00615911120553573 409.67259176716 192.76058338896 2.12529234226535 0.0340155672660228 1228.17995924804 403.259421870521 3.04563239601724 0.00243525858582096 TNFAIP2 other 1 1 1 2.12529234226535 3.04563239601724 2.41318710879598e-25 49.1543049763626 22.0001986721249 2.23426641317757 0.0258740103717831 -362.752050051579 42.2013381479718 -8.59574757510416 8.95554573794901e-17 ZNF445 other 3.13231686721718e-21 1.36043695305183e-12 1 2.23426641317757 -8.59574757510416 5.67402415837823e-10 24.9514337290032 3.9627736061344 6.29645702958611 6.54730970531806e-10 -39.2315911951595 24.8604350899985 -1.57807339465843 0.115165149071594 PGBD2 other 4.71227706353312e-06 1 7.33756998674995e-06 6.29645702958611 -1.57807339465843 4.73824621177688e-21 270.345366612973 50.6473567894781 5.33779813498849 1.39035476728369e-07 -945.451649667618 146.211811839769 -6.46631512031138 2.25989897752855e-10 RAB11B other 5.73138261776531e-17 3.21041248747706e-06 0.00140717805996783 5.33779813498849 -6.46631512031138 8.96514854207622e-24 126.878660266948 13.5309714796295 9.37690693221547 1.82566105389066e-19 -68.7245746568549 36.1069789832356 -1.90335986538125 0.0575220978466892 PRMT3 other 1.13722909256237e-19 1 2.49677405730087e-15 9.37690693221547 -1.90335986538125 0.217793133610907 1.2905922541309 1.52403967183093 0.84682326712692 0.39746532689991 -2.94226041824801 2.85045428044336 -1.0322075461566 0.302432728739454 GP1BA other 1 1 1 0.84682326712692 -1.0322075461566 2.03079416142059e-22 194.122608024692 30.7873369056796 6.30527442563182 6.10731599744381e-10 -418.4344418362 69.7322956794804 -6.00058319834335 3.66695420829638e-09 PRPF39 other 2.5214340308198e-18 5.07029758381141e-05 6.85546220713067e-06 6.30527442563182 -6.00058319834335 4.25676989723928e-15 9.13361324888574 4.08676495158039 2.23492502189383 0.0258429463962677 -60.1542228735479 10.1299397592336 -5.93826067116698 5.24932864490699e-09 PPIL6 other 4.40873658257072e-11 7.23095020835938e-05 1 2.23492502189383 -5.93826067116698 7.09189509633166e-29 130.274872025078 13.0529543759369 9.98048934157303 1.25727024563291e-21 -21.0909470772124 26.6638366791368 -0.790994459312567 0.429297734674769 ZNF74 other 9.60597190798123e-25 1 1.75414344670704e-17 9.98048934157303 -0.790994459312567 1.58834715074861e-14 5.3057511711828 4.57933425166336 1.15862937265511 0.247116589077881 -74.8008110610266 10.6228865821826 -7.04147695471842 5.77552675921815e-12 KIAA0825 other 1.61074284557417e-10 8.41320983015308e-08 1 1.15862937265511 -7.04147695471842 4.88202893044007e-10 225.699446287444 34.4524204330774 6.55104760276153 1.32800309693697e-10 298.699698797414 111.238272123687 2.68522418673752 0.00746973876066057 UBALD2 other 4.06624189616354e-06 1 1.52441475497394e-06 6.55104760276153 2.68522418673752 1.27939102863941e-05 7.14347844508519 1.55615631294391 4.59046330093362 5.49780584104798e-06 -4.78235318018103 7.05736498862758 -0.677640052326532 0.498288037601977 CDNF other 0.0770577216549515 1 0.0504753554266615 4.59046330093362 -0.677640052326532 0.0232814964087684 4.19000617473607 4.23972836563035 0.988272316854695 0.323471103622829 32.464652091903 11.9891145558278 2.70784401472936 0.00699132924099056 NOTUM other 1 1 1 0.988272316854695 2.70784401472936 0.162219027969204 2.86010637784404 8.3594476146755 0.342140594651608 0.732390305333868 -41.8785117398536 24.7929100904573 -1.68913256197273 0.0918237593745786 RBM11 other 1 1 1 0.342140594651608 -1.68913256197273 7.47443445036372e-12 123.95285557634 17.1384215236938 7.2324545994493 1.64013650274917e-12 -94.4318706486914 129.326766817461 -0.730180402499179 0.465597741489849 ZBTB37 other 6.81967399251186e-08 1 1.98587727752869e-08 7.2324545994493 -0.730180402499179 0.0246285111800554 17.7007551103978 8.57698641172416 2.0637499304187 0.0395360756221667 -51.0954323437307 37.1839821935829 -1.37412480669025 0.169993779630824 NUPR2 other 1 1 1 2.0637499304187 -1.37412480669025 4.29825660668903e-25 175.553810823073 15.9664580146165 10.9951631515495 1.76157798299606e-25 -2.18748920116585 44.8605382063056 -0.0487619919115989 0.961127272664024 CCDC137 other 5.55764579244891e-21 1 2.52997829917894e-21 10.9951631515495 -0.0487619919115989 2.72512329699463e-09 27.0838832697528 4.330282689497 6.25453006461774 8.12493185322896e-10 -3.28650308608219 16.1591048509849 -0.203383981748337 0.838911677074136 SFTPA2 other 2.17955361293631e-05 1 9.07554888005674e-06 6.25453006461774 -0.203383981748337 0.206862195797197 20.8255472446802 14.7121421474001 1.41553466762557 0.157503592616568 -47.8703629474451 58.1786111693204 -0.822817217278105 0.410984803859714 RGPD2 other 1 1 1 1.41553466762557 -0.822817217278105 4.38019453420322e-13 11.0043095996695 23.7193837814163 0.463937415114938 0.642881999932333 -385.614168812421 55.8630929653178 -6.90284315356164 1.45347591523259e-11 ARL15 other 4.19272220813932e-09 2.10579590598898e-07 1 0.463937415114938 -6.90284315356164 6.82887772358456e-15 115.644815681351 33.9581649587354 3.40550839015824 0.000710774217037398 -278.368811182939 73.230263877019 -3.80128100658526 0.000160768267434843 CDK10 other 7.02486651425143e-11 1 1 3.40550839015824 -3.80128100658526 7.94987943499911e-07 5.73390291230948 1.61999557647408 3.53945590690396 0.000436007394897041 21.0658656505265 4.56758860396265 4.61203218526524 4.9984611106863e-06 TMEM105 other 0.0053613986909634 0.061426088589224 1 3.53945590690396 4.61203218526524 0.0696957955528525 1.94956344368107 3.33400009943351 0.584752065248087 0.55895777174626 40.1238731134634 17.358683488543 2.31145830500025 0.0211817164585891 SOCS1 other 1 1 1 0.584752065248087 2.31145830500025 2.46856748678065e-16 214.227749971051 25.3050789305451 8.46580050427987 2.3916148127873e-16 105.460776506204 54.7776743496842 1.9252510764326 0.0547208869896376 TCN2 other 2.66037518050351e-12 1 3.13158043586369e-12 8.46580050427987 1.9252510764326 2.07952562842501e-15 74.1402439289993 29.4242441468243 2.51969918272314 0.0120345097289088 -332.544162010744 56.0106028615622 -5.93716448352952 5.20927063942989e-09 GAS2L1 other 2.17497585476972e-11 7.17681215994255e-05 1 2.51969918272314 -5.93716448352952 9.16939921777401e-08 85.4058151325525 15.9533399572241 5.35347553312049 1.27350545399973e-07 -19.4182557262377 36.646391833383 -0.529881790669188 0.596409685846503 ATP6V0A2 other 0.000664139585343372 1 0.00129197128308273 5.35347553312049 -0.529881790669188 0.00177416847927097 1.81053497027535 4.1603886573856 0.435184094414173 0.663600772501853 -25.3563250421655 8.74735603686584 -2.89874162378906 0.00389725058212291 PRKN other 1 1 1 0.435184094414173 -2.89874162378906 3.32927274126938e-08 129.71109878938 27.0655570106509 4.79247845290367 2.13822338924892e-06 -120.748930027769 69.5200906321429 -1.73689258644234 0.0829827745905198 HS6ST3 other 0.000249362528321076 1 0.0201741376775636 4.79247845290367 -1.73689258644234 1.97458392727483e-23 446.900470487329 42.912620438011 10.4141967077703 3.06852063423208e-23 -95.7870348732422 120.570463839241 -0.79444858900897 0.42728857287086 HGS essential 2.49074016586447e-19 1 4.34287725362867e-19 10.4141967077703 -0.79444858900897 9.66203766950683e-09 -0.257338561850135 18.3446114861064 -0.0140280191840004 0.988812742001265 -274.472807142385 47.5704309337717 -5.76981964961617 1.32952296440905e-08 TNFAIP8L1 other 7.47656795247794e-05 0.000181160799130377 1 -0.0140280191840004 -5.76981964961617 1.4714325921021e-45 129.529970928849 9.84069573104483 13.1626842724357 1.71317229665293e-34 -83.7735605025402 26.6668445448208 -3.14148756376991 0.00177356669594051 RAD51D essential 2.20082172800712e-41 1 2.5563957010655e-30 13.1626842724357 -3.14148756376991 0.00250296190246849 20.8913692780646 10.2539448356361 2.03739825139879 0.0421044815215429 -37.3932511191326 21.8576627151884 -1.71076164942141 0.0877080818065932 MAPK11 other 1 1 1 2.03739825139879 -1.71076164942141 0.00279074769744932 42.1652822738328 19.5856114244556 2.15287035773533 0.0317678570407523 -74.1178597833439 39.8073344439582 -1.86191466519038 0.0631541230213952 SP140L other 1 1 1 2.15287035773533 -1.86191466519038 3.21832741412576e-15 98.4539451405348 14.5602481056714 6.7618315585011 3.5233526262668e-11 -178.741073484592 47.3043368138356 -3.77853460218711 0.000175172173627741 MRPL30 other 3.34770417617362e-11 1 4.11175251485335e-07 6.7618315585011 -3.77853460218711 7.76648324658159e-26 64.8203976993484 6.12627009901205 10.580728020758 7.11881429277842e-24 -29.2926729806198 19.8400538483138 -1.47644120346525 0.140417142873746 TARSL2 other 1.01577834382041e-21 1 1.01265133314773e-19 10.580728020758 -1.47644120346525 4.22197635550374e-05 98.6474991687519 25.8073610003032 3.82245589417659 0.000147454970657272 -371.094211446191 161.809361825933 -2.29340383806344 0.0222066375997451 SMYD3 other 0.241370388244149 1 1 3.82245589417659 -2.29340383806344 0.288659931604469 109.514526598153 79.266491406164 1.38159926919178 0.167662960394637 -83.9569968606623 233.01877556162 -0.36030142488866 0.718761838925341 METTL7A other 1 1 1 1.38159926919178 -0.36030142488866 0.279179797360196 11.9917280494533 9.81102561842332 1.22227058779003 0.222130771788062 -4.49407537268871 16.5512020283676 -0.271525618803165 0.786089054738446 IFNLR1 other 1 1 1 1.22227058779003 -0.271525618803165 0.650822597220585 18.197655166501 20.2253834767332 0.899743393614028 0.368660113512616 23.7378035750715 60.5986784101191 0.391721473105717 0.695419420175583 SH3BGR other 1 1 1 0.899743393614028 0.391721473105717 5.39221159979507e-28 195.901909737275 56.7200120280392 3.4538411176717 0.000596551344090379 -1499.18762459411 146.211608601536 -10.2535471631379 1.21931347208549e-22 FAM174B other 7.23365186112509e-24 1.89164292059342e-18 1 3.4538411176717 -10.2535471631379 0.0811189533584245 -58.1342511020263 73.1769581681379 -0.794433829409141 0.427289343727683 -376.260654834143 167.487177750571 -2.24650423923487 0.0250720391056213 GPRIN3 other 1 1 1 -0.794433829409141 -2.24650423923487 0.0850895505914402 -79.5376778790437 397.316453045226 -0.200187224237578 0.841408425568954 2545.34144132387 1221.54652522803 2.08370404954385 0.0376498559622838 KRT6B other 1 1 1 -0.200187224237578 2.08370404954385 2.33611196263907e-06 43.8485171524658 8.52271953923668 5.14489734768311 3.73856902900941e-07 37.2525063558636 20.5908643544259 1.80917642477968 0.0709734528957006 PARPBP other 0.0150959555025737 1 0.00369781862659321 5.14489734768311 1.80917642477968 0.0291433686764202 16.0190905623902 47.9298386067933 0.334219580704362 0.738348618941651 375.544520051335 141.649958835517 2.65121517251843 0.00826489567739174 STAC3 other 1 1 1 0.334219580704362 2.65121517251843 0.290754788365837 24.815542832699 15.8247447209649 1.56814806622586 0.117432347386181 20.8458660086942 31.0038914437311 0.672362888591816 0.501640285981527 ROR1 other 1 1 1 1.56814806622586 0.672362888591816 2.86745436355587e-10 38.3773483864667 5.67313905721626 6.76474664192314 3.48759164316078e-11 -5.5845058736297 26.6419413474441 -0.209613323623861 0.83404868254455 SDHAP1 other 2.41812426478667e-06 1 4.07036820673294e-07 6.76474664192314 -0.209613323623861 6.16626388824279e-07 2980.6939477098 596.853115375595 4.99401589926204 8.06269752911632e-07 11354.2728170841 6189.67927690798 1.83438790753567 0.0671621732986171 MUC1 other 0.00419244281761627 1 0.00780549747793751 4.99401589926204 1.83438790753567 3.18323963258888e-18 181.714408130667 25.8042816652355 7.04202544709775 5.88072791068688e-12 -347.048284927627 72.5016132237876 -4.78676638347905 2.19946404339155e-06 FAAP100 other 3.61202201109861e-14 0.0274933005423944 7.01806068861372e-08 7.04202544709775 -4.78676638347905 1.70636636176299e-08 127.913161789447 63.1056923452045 2.02696709339198 0.0431574805949629 -493.367581444896 129.763269002783 -3.80205882016053 0.000159890354208103 IRF7 other 0.000130195753402516 1 1 2.02696709339198 -3.80205882016053 0.000900873262869943 10.6884693585731 4.73126441124055 2.25911477979954 0.0242824675438697 -77.8445436791656 29.5963809277164 -2.63020481690942 0.00878192762754347 L3MBTL1 other 1 1 1 2.25911477979954 -2.63020481690942 0.00106611881462497 12.6131502364028 6.00275044591348 2.10122848684964 0.0360872066372708 54.2941268085739 15.5626925403201 3.4887360697969 0.000525214059498632 SV2B other 1 1 1 2.10122848684964 3.4887360697969 0.000345360016760481 11.6139839345689 2.91530145351415 3.98380205949859 7.71614466006344e-05 11.9436653984084 4.82275239666796 2.47652469296584 0.0135732336560461 FAM131C other 1 1 0.644220917668697 3.98380205949859 2.47652469296584 7.93414843423625e-09 18.7496421066666 13.9576331722636 1.34332532423374 0.179730908378864 -127.63645585698 28.6911299439995 -4.44863817166163 1.04989343249817e-05 LMNTD2 other 6.17514772636607e-05 0.126606649024954 1 1.34332532423374 -4.44863817166163 0.963956290368089 0.0802159145291629 0.657052555784589 0.122084472273876 0.902878220630328 0.479186373891218 1.84610332832377 0.259566388586879 0.795298680264684 PDE6G other 1 1 1 0.122084472273876 0.259566388586879 0.00127758359686647 -42.8405092547756 16.4513798701196 -2.60406784069135 0.0094669941672052 -144.884007980658 44.2288383107722 -3.27578144744921 0.00112157172447504 PRKG1 other 1 1 1 -2.60406784069135 -3.27578144744921 0.288150649044847 349.959375038522 291.077163995138 1.20229072674477 0.229773975073416 -296.623007493248 598.706881281517 -0.495439449198136 0.620490021843735 DLK1 other 1 1 1 1.20229072674477 -0.495439449198136 1.07127615641441e-05 76.9903967700451 19.1999387848514 4.00992928325323 6.92564031430137e-05 -28.46653585241 35.1425298577727 -0.810030921724148 0.418277896595774 TLCD2 other 0.0649836116480983 1 0.580576427547884 4.00992928325323 -0.810030921724148 0.272462684962095 -29.6585722474984 18.4021433536662 -1.61169118604815 0.107611286001453 -22.2094091827858 58.7179751682613 -0.378238675961542 0.705401391041679 LSAMP other 1 1 1 -1.61169118604815 -0.378238675961542 0.0729192147246955 164.216390001447 78.0072896321132 2.10514159350878 0.0357534864857232 432.049648940787 309.396769746224 1.39642585569063 0.16317638992099 AHNAK2 other 1 1 1 2.10514159350878 1.39642585569063 7.28832589259806e-07 -27.0627754079304 49.8055801500438 -0.54336833998121 0.587099210060862 -596.232194188836 113.338458349398 -5.26063441193794 2.06916184470626e-07 OLFML2A other 0.00492836596857481 0.00269880779405037 1 -0.54336833998121 -5.26063441193794 2.52155870402219e-09 38.8121314211821 73.3881947194423 0.528860691689692 0.597119800627817 -1261.0925330496 211.240227535048 -5.96994496628425 4.30743995732446e-09 SP1 other 2.02128145714419e-05 5.94642086108642e-05 1 0.528860691689692 -5.96994496628425 5.93041098886932e-31 156.508253749517 24.6108690268311 6.35931439799584 4.33818664361957e-10 -284.806479386462 48.2189621313735 -5.90652446252371 6.2050288382846e-09 MRPL40 essential 8.18871149343075e-27 8.5312941497575e-05 4.8999818139683e-06 6.35931439799584 -5.90652446252371 0.0475877903477442 -6.2955177456385 2.66964432065998 -2.35818595642814 0.0187280933994856 -8.71898136750936 4.8308562674488 -1.80485215970085 0.0716674151780464 FAM212A other 1 1 1 -2.35818595642814 -1.80485215970085 0.000683250228853925 2.18703141527206 2.28930756627652 0.955324416644109 0.339853334040022 38.7474588418894 10.1368055239919 3.82245262081646 0.000147972533953789 PDIA2 other 1 1 1 0.955324416644109 3.82245262081646 4.00646276596915e-32 464.582321053069 51.1113111452889 9.08961853340934 2.21467523335556e-18 -495.195012352619 114.352482232193 -4.33042643837956 1.79304188601988e-05 PCGF3 other 5.59141943618655e-28 0.213120958572323 2.99003303255334e-14 9.08961853340934 -4.33042643837956 8.91722256873928e-10 52.1659609013317 10.7524302129384 4.85155075348088 1.61720966948618e-06 -208.078175395485 46.4936815433076 -4.47540759278583 9.35892698121266e-06 LMLN other 7.31479767313683e-06 0.113177503983805 0.0153651090697882 4.85155075348088 -4.47540759278583 5.87545651833282e-16 5364.50062955188 619.466457801889 8.65987264038031 5.70898530364884e-17 2841.71048825705 1742.34465329554 1.63096921317038 0.103490869231271 P4HB other 6.25559855506895e-12 1 7.56040923762216e-13 8.65987264038031 1.63096921317038 9.33081346565697e-18 461.532988533555 78.1457106562903 5.9060565788892 6.22158907339315e-09 -462.851677957718 160.474386298228 -2.88427136962248 0.00408066266015456 PSMD13 essential 1.04682396271206e-13 1 6.71620540472791e-05 5.9060565788892 -2.88427136962248 2.04166943354438e-06 1360.48956462524 273.689201240124 4.97092891667142 8.99579702974413e-07 -3552.38586350197 2421.75969862769 -1.46686141714017 0.143003520231592 PBX1 og 0.0132626846403043 1 0.00868004455400012 4.97092891667142 -1.46686141714017 0.544366414392177 21.755992631107 57.9162439818382 0.375645779756183 0.707333734607765 187.745577150666 171.142056640655 1.09701601602739 0.273143115409546 NDUFA4L2 other 1 1 1 0.375645779756183 1.09701601602739 6.34138000729083e-07 22.5633221463449 45.2254985149651 0.498907096377913 0.618049904058376 401.996467526603 79.5648275050431 5.05243937719997 5.99567330324647e-07 SHC4 other 0.00430960185295485 0.00769065014607425 1 0.498907096377913 5.05243937719997 0.943507754276686 11.4186515408014 33.9012498735617 0.336820960389027 0.736381294656341 4.10321888482678 101.235511501405 0.0405314185108834 0.967684275422843 KRT79 other 1 1 1 0.336820960389027 0.0405314185108834 5.54343461114601e-06 -606.125411588562 416.318266234384 -1.45591837002732 0.146001743997916 -3986.07460494149 813.364992838666 -4.9007206359226 1.26763300628484e-06 ZFP36L1 other 0.0344469026736613 0.0160203459334278 1 -1.45591837002732 -4.9007206359226 4.54188914768104e-56 497.802198578255 40.3399987960241 12.3401639423777 6.63083481363065e-31 -501.370182615244 87.0951426830131 -5.75658030023563 1.4599714537491e-08 UBE2L3 essential 6.94046080657139e-52 0.000198643715997103 9.78247060054929e-27 12.3401639423777 -5.75658030023563 0.393862167147222 1.04750104810407 3.88367589160562 0.269718966602797 0.787479124537697 -16.238891875562 13.42006760316 -1.21004545996015 0.226788916534386 NTF3 other 1 1 1 0.269718966602797 -1.21004545996015 1.84418128262804e-11 209.074918500055 57.6934433455185 3.62389391889704 0.000317837872234847 -926.368638946965 173.678893835085 -5.3338008925056 1.4207462274368e-07 BRWD1 other 1.64925132105425e-07 0.00186913373681585 1 3.62389391889704 -5.3338008925056 9.58280784784358e-07 20.7309949900758 4.85881503144364 4.26667713339897 2.34450452037396e-05 -27.4961987396107 14.2691571924762 -1.92696726013424 0.0545100035169306 PMEL other 0.00641089845020736 1 0.205003475261499 4.26667713339897 -1.92696726013424 0.712016914555337 -1.09765516518201 1.3840517097485 -0.7930738118025 0.428087701927236 -0.961653095543466 2.97547194540385 -0.323193467519972 0.746675484390358 SNAI3 other 1 1 1 -0.7930738118025 -0.323193467519972 1.09751952419491e-10 3.63184880899649 3.62162733316507 1.00282234335317 0.316414801268748 -54.4174792040784 9.25363067127903 -5.88066253529836 7.33218338160103e-09 ZBTB3 other 9.448545583794e-07 0.000100656213462619 1 1.00282234335317 -5.88066253529836 2.30785779708687e-08 23.013195078748 10.1257161415404 2.27274740443663 0.0234349866083499 -110.252573479072 23.9553658722365 -4.60241659706191 5.21505055463737e-06 EP400NL other 0.000174750992395418 0.0640303907098376 1 2.27274740443663 -4.60241659706191 5.21988721769353e-08 672.71835522613 115.165912264051 5.84129749854915 8.89566431273257e-09 566.298887119568 269.275586256062 2.10304578663533 0.0359179691410732 PRAME other 0.000386323852981498 1 9.53793127611186e-05 5.84129749854915 2.10304578663533 4.38920084638186e-10 28.465016789018 10.7523725204427 2.64732427516807 0.00835235493035821 -165.265273234297 32.8386852147968 -5.03263977084654 6.61828593217833e-07 C6orf201 other 3.66717730715205e-06 0.00847140599318827 1 2.64732427516807 -5.03263977084654 4.7683721359137e-13 148.013123955897 19.2868307440324 7.6743103063573 8.18250941607883e-14 -29.2125766573616 176.497313858921 -0.165512868262187 0.868604157758732 MYBL1 other 4.55904059914709e-09 1 1.02084987475000e-09 7.6743103063573 -0.165512868262187 3.79723693493598e-55 380.611799891965 28.3138168641631 13.4426171405278 9.1333712236103e-36 -245.447302104755 58.3397742395284 -4.20720349545767 3.0247663719361e-05 DRG1 other 5.79116604947087e-51 0.353716179534208 1.3673570058867e-31 13.4426171405278 -4.20720349545767 1.48881669928899e-36 268.599522825983 46.4359088822246 5.78430635453334 1.22482225092708e-08 -787.453977132591 86.5490853081553 -9.09835123420295 1.68878356115477e-18 ANKFY1 other 2.14300275695657e-32 2.58772305075746e-14 0.000130664037728901 5.78430635453334 -9.09835123420295 7.44841065593419e-43 456.273527730238 30.4968086771782 14.9613532537155 2.39035110952451e-42 -419.13204703948 258.908187773906 -1.61884431173529 0.106087085846157 YTHDF3 other 1.10407791152913e-38 1 3.6275968438144e-38 14.9613532537155 -1.61884431173529 1.6318276900223e-34 39.5253196341014 2.96365882460932 13.3366632170664 4.97915151689717e-35 -10.9941419403362 20.6556445049573 -0.532258479646937 0.594778327910117 ZNF696 other 2.32045897521171e-30 1 7.44084402685113e-31 13.3366632170664 -0.532258479646937 0.370475694396622 -0.705591333928749 2.9507065840414 -0.239126227509326 0.811099452143534 -17.0602869172625 12.0951675123277 -1.41050439358316 0.158973040675992 ADARB2 other 1 1 1 -0.239126227509326 -1.41050439358316 0.971723398987469 -0.438641854764619 3.66974017515734 -0.11952940367115 0.90490064926556 1.40593103644081 8.74799302616884 0.160714695614765 0.872378554479314 NRG3 other 1 1 1 -0.11952940367115 0.160714695614765 0.43761818560094 43.3189623978276 34.4487483751774 1.25749016846841 0.209115753315605 14.6455596797344 171.204689014365 0.0855441504788782 0.931860270823115 SRL other 1 1 1 1.25749016846841 0.0855441504788782 1.14843969505354e-05 1621.03500837266 354.351897125809 4.57464746632112 5.93171160811193e-06 307.78520445329 684.936738454992 0.449362966202629 0.653351486755971 IFIT1 other 0.0694806015507393 1 0.0543463417535215 4.57464746632112 0.449362966202629 0.0166775368897111 -1.30308910646395 19.6796012136409 -0.0662152191153505 0.947231170155879 -114.228842886907 45.2057602548448 -2.52686476774085 0.0117951621530096 KCNQ5 other 1 1 1 -0.0662152191153505 -2.52686476774085 1.04129002988607e-13 -12.4126334465757 8.31050533434608 -1.49360754216427 0.135882412373152 -112.574518942665 14.8445556481267 -7.58355599258851 1.55012223192048e-13 ADAMTSL5 other 1.02358809937801e-09 2.29697112325976e-09 1 -1.49360754216427 -7.58355599258851 0.00054257748117594 2.63909281355314 2.05237240736098 1.28587424196888 0.199036033520708 -9.42641861736042 3.72467152086893 -2.53080535143709 0.0116618902902478 KCNIP4 other 1 1 1 1.28587424196888 -2.53080535143709 1.65650549656668e-39 868.914505775492 61.839725103823 14.0510732270667 1.8263900788689e-38 -10.3316257790036 149.620356024314 -0.069052273724871 0.94497347797641 MORF4L1 other 2.42048583158323e-35 1 2.75218720984755e-34 14.0510732270667 -0.069052273724871 6.2829707101158e-54 63.9592182979126 3.63494328454801 17.5956578386795 4.66974598552258e-55 -16.9073893029448 17.3023845672279 -0.977171050455598 0.328924472447068 WDR53 other 9.56645120322232e-50 1 7.18954091931057e-51 17.5956578386795 -0.977171050455598 8.45495648922928e-18 64.229896902617 12.5058458845064 5.13598979995364 3.90919399844069e-07 -205.258870102001 37.4548464280795 -5.48016851427059 6.4936427458724e-08 DMWD other 9.4991436156491e-14 0.000864563595185451 0.00386150183165971 5.13598979995364 -5.48016851427059 2.14705666009911e-28 418.107373475449 34.9497028704691 11.9631166829956 3.72923444329741e-29 33.213317494161 238.774479391349 0.139099109665421 0.889428290716304 SLC52A2 other 2.89315884948356e-24 1 5.45997214843173e-25 11.9631166829956 0.139099109665421 1.58472360199153e-15 84.4623188281546 12.7015961587147 6.64974053439764 7.25053266212113e-11 -147.868777140947 38.7545260768922 -3.81552278171492 0.000151727074991532 PIGP other 1.66332589265031e-11 1 8.38379091721067e-07 6.64974053439764 -3.81552278171492 0.417560749091491 -16.9605085009383 16.940352386077 -1.00118982854677 0.317180985604147 42.1835062101001 67.256254304268 0.627205702227505 0.530788038165242 IKZF1 other 1 1 1 -1.00118982854677 0.627205702227505 8.37320306134323e-12 163.148802363255 22.7276592241158 7.17842522868092 2.40052629482122e-12 -4.93967445498242 63.9598921869769 -0.0772308127184149 0.938469130937723 PCYT2 other 7.62045210612848e-08 1 2.89407450103646e-08 7.17842522868092 -0.0772308127184149 0.000757690427527581 185.825570159618 51.4792477820277 3.60971805467003 0.000335281502011423 68.9576596232264 103.771420690497 0.664514942210302 0.506646562775894 NAT8L other 1 1 1 3.60971805467003 0.664514942210302 8.83359860419729e-13 47.257331273146 6.71461048813101 7.03798550290889 5.97912503644592e-12 14.4263302604468 13.7241904062381 1.05116074853418 0.293657560613468 GNB1L other 8.36011771901231e-09 1 7.13369408098363e-08 7.03798550290889 1.05116074853418 8.06412616583155e-09 46.4755478943315 7.53234065096882 6.17013356775808 1.34457341986951e-09 -13.2065727501305 47.8356919076328 -0.276081984465311 0.782591312693017 DNAH14 other 6.27227733178378e-05 1 1.48871169047952e-05 6.17013356775808 -0.276081984465311 0.543672791255312 -19.0806135694817 18.1863824513875 -1.04917036802038 0.294588962834958 -5.0730456688349 44.2900361361384 -0.114541466013742 0.908852960782524 EVI2B other 1 1 1 -1.04917036802038 -0.114541466013742 5.7897154187113e-07 25.6708331764405 5.7556989052126 4.46007228647626 9.96242158877403e-06 -54.2476166667563 26.5502404740178 -2.0432062270714 0.041514216547416 ZNF829 other 0.00394627002939362 1 0.0897913057796203 4.46007228647626 -2.0432062270714 5.8954621812706e-13 83.8633831610073 11.4285202249357 7.33807890351603 7.94803546719548e-13 -27.6891723244447 42.302144238688 -0.654557181976635 0.513030047276405 THNSL1 other 5.61365908900586e-09 1 9.67991239549738e-09 7.33807890351603 -0.654557181976635 0.000536467117579921 141.141506286601 36.8156331450084 3.83373839397727 0.000141369263233013 73.1600022076985 65.5618951387804 1.11589212076366 0.264973990474945 TRIM69 other 1 1 1 3.83373839397727 1.11589212076366 2.2613068498659e-15 530.718334833771 84.7475586320967 6.26234364033668 7.70571819741868e-10 -1265.62193591294 390.360013129418 -3.24219154971014 0.00125879909816275 ATP6V0C other 2.36261339673989e-11 1 8.61730466017331e-06 6.26234364033668 -3.24219154971014 2.39827655996679e-06 1779.75757310481 532.187471020226 3.34423050150531 0.00088259900968191 -1719.17102663884 1090.44346215143 -1.5765797001955 0.115480064127865 IFITM1 other 0.0154760786414657 1 1 3.34423050150531 -1.5765797001955 1.55676175653103e-49 2230.56113565004 144.911800574033 15.3925430973475 1.32399074245437e-44 -1005.7088087846 415.330486189955 -2.4214663797269 0.0157858778349786 LAMP1 other 2.35086592853751e-45 1 2.01484911186707e-40 15.3925430973475 -2.4214663797269 1.42592940580091e-08 16.0741416896659 3.25582758007189 4.93703714166308 1.17914106865517e-06 -25.1427277641153 13.7230702327508 -1.83215033791133 0.0676933850184071 POMK other 0.000109240451778408 1 0.0113020671430598 4.93703714166308 -1.83215033791133 2.36702056305819e-06 42.0260058881256 8.18768985832547 5.13282825990195 4.17567855273975e-07 45.3614107085001 23.471389113004 1.93262573808928 0.0538789870949463 LINC00839 other 0.0152838517756667 1 0.00411888932442249 5.13282825990195 1.93262573808928 4.04271331500289e-13 91.7136043286566 26.0920201116953 3.51500588823889 0.000478061156720271 -209.260674912467 47.2307094476044 -4.4306062170125 1.14606508139935e-05 KLHDC8B other 3.87696206908777e-09 0.137848707990714 1 3.51500588823889 -4.4306062170125 1.59937676438449e-17 44.7931537432943 6.87833218692049 6.51221146726105 1.70889828164559e-10 -99.6167900701477 20.7295265757316 -4.80555065771598 2.00760292176147e-06 SETD4 other 1.78122590249501e-13 0.0251371961833753 1.95446696471806e-06 6.51221146726105 -4.80555065771598 0.000414492015415043 60.4500683270148 15.4125335955836 3.92213700311651 9.90385885881909e-05 61.246927978403 32.0290800683059 1.91222875736008 0.0563737159791803 PTCH1 ts 1 1 0.818950089035751 3.92213700311651 1.91222875736008 1.94006315885712e-30 -5.6635959127701 38.4994387150265 -0.147108532015029 0.883100758103758 -806.017577994926 70.7614184022999 -11.3906362562219 4.12569588309318e-27 RTN4RL1 other 2.66400478621368e-26 6.43938613433184e-23 1 -0.147108532015029 -11.3906362562219 0.00094526508315799 9.98766702343026 15.4129996483324 0.648002806157908 0.517268597006154 -90.1761045913532 29.5104074945756 -3.05573905097477 0.0023601193147899 RNPC3 essential 1 1 1 0.648002806157908 -3.05573905097477 0.000405380399662127 33.5867815092662 8.57885561228066 3.91506548509647 0.000103322201552416 11.4896740120961 52.1439529890425 0.220345281734021 0.825694976796149 ZNF267 other 1 1 0.852511485008983 3.91506548509647 0.220345281734021 1.08479198948147e-07 253.776877715029 61.0379681566075 4.15768881860392 3.76536889454289e-05 -332.824553039544 146.107993062372 -2.27793528652101 0.0231393147759762 IRS2 other 0.000783219816405619 1 0.323445188041234 4.15768881860392 -2.27793528652101 2.49077812314786e-07 89.8474486442266 26.2382430916375 3.42429362859521 0.000663049254709138 -174.131653731996 57.2838025292026 -3.03980612396019 0.00248161439760393 BICD2 other 0.00174927347588674 1 1 3.42429362859521 -3.03980612396019 0.00199316876042033 59.5270549462695 20.3424020032876 2.92625496913537 0.00357618865211333 -71.0212392535621 58.5611970272258 -1.21276959589032 0.225752158061744 RASA3 other 1 1 1 2.92625496913537 -1.21276959589032 3.73894175553307e-15 93.1412328045327 11.2860045090406 8.25280839910369 1.25292062974031e-15 -82.0660591848615 48.7975374515229 -1.68176640606893 0.0932076941097782 LRCH3 other 3.87952596554111e-11 1 1.61902403775043e-11 8.25280839910369 -1.68176640606893 0.0582538561620117 2.80389410293656 3.96094276525186 0.707885538648593 0.479320070804961 81.7850632584339 36.3614859758342 2.24922224885936 0.0248982628774381 LEMD1 other 1 1 1 0.707885538648593 2.24922224885936 4.83158554322032e-05 467.38291611461 146.091139808809 3.19925572985658 0.00146024497646957 -983.876822226836 475.889619170018 -2.0674475395004 0.039176814337948 NDUFA13 other 0.273854268589728 1 1 3.19925572985658 -2.0674475395004 1.80342308694045e-27 59.8095173829768 5.61533667312638 10.6511008804174 3.59340980561157e-24 -58.7385319516541 25.1006591444417 -2.34011910259581 0.019641518255097 ZNF566 other 2.40702879413942e-23 1 5.11989029103537e-20 10.6511008804174 -2.34011910259581 1.78942324376766e-20 69.670742372909 8.15543424351893 8.54286115154149 1.34166487282384e-16 -103.678346012936 35.8340908939979 -2.89328802339736 0.00396622073812245 ZNF529 other 2.13836077630235e-16 1 1.76415514127607e-12 8.54286115154149 -2.89328802339736 1.00347886197773e-20 19.9451782356202 3.04435950187978 6.55151870970063 1.31829937090387e-10 -54.8533846533298 10.3229372294386 -5.31373807998179 1.5670025969799e-07 ZNF284 other 1.20557950478004e-16 0.00205606410749733 1.51353950773473e-06 6.55151870970063 -5.31373807998179 0.156858196792785 2.68418431203997 1.41618599456593 1.89536143016489 0.0585812704616911 3.34055739375608 2.60625160864586 1.28174784916171 0.200484240586991 DLEU7 other 1 1 1 1.89536143016489 1.28174784916171 0.000738051236213485 3.98422948869008 3.37927295625199 1.17901973006319 0.238909539305491 -15.5721307418613 5.6186039794578 -2.77153022330718 0.00577178063299833 MATN1-AS1 other 1 1 1 1.17901973006319 -2.77153022330718 3.32977720611525e-21 159.639025576317 16.4791320935091 9.68734425274718 1.452823907088e-20 -202.219094442195 101.955517997218 -1.98340510071963 0.047830139717284 AIDA other 4.03968570645903e-17 1 2.00823848676774e-16 9.68734425274718 -1.98340510071963 0.000258413464608021 20.061558693338 6.5300214863932 3.07220408617963 0.00223118160588613 45.9503280350503 11.8671107239664 3.87207375947463 0.000121033801470694 C15orf41 other 1 1 1 3.07220408617963 3.87207375947463 0.106397690829435 2.56524171110142 1.8816097362586 1.3633229365629 0.173350991810028 11.6653152625935 6.16716319012305 1.89152044513367 0.0590917458432196 CD300LF other 1 1 1 1.3633229365629 1.89152044513367 0.631673137891685 -179.926573573791 1323.8443739611 -0.135912179039164 0.891940618225879 3602.55171725201 4087.41401120973 0.881376759822228 0.378500334638464 KRT5 other 1 1 1 -0.135912179039164 0.881376759822228 0.0887758849617825 15.1537364631505 17.596416881003 0.861183078670431 0.389525185067148 -62.7624394622339 40.7101103504478 -1.54169170562181 0.123743110378892 NBPF6 other 1 1 1 0.861183078670431 -1.54169170562181 1.44551083108385e-07 23.6962678088271 16.2780194384742 1.45572180315865 0.146048506108332 -271.203661298381 54.2079542174952 -5.00302336093053 7.63823416163141e-07 GSAP other 0.00103469665288982 0.00975402502440332 1 1.45572180315865 -5.00302336093053 0.0548696615463428 2.20882423888073 2.08873432850512 1.05749410479673 0.290763393715687 -7.11435886845012 4.25341813963446 -1.67262155633293 0.0949864499965111 AGBL4 other 1 1 1 1.05749410479673 -1.67262155633293 3.83400153873978e-20 46.1833672675115 9.42847941853487 4.89828372290048 1.28342757001577e-06 -125.26709617398 21.4667612257251 -5.83539803032159 9.3136336954124e-09 CYP2R1 other 4.551343226638e-16 0.000127457077121719 0.0122747012796308 4.89828372290048 -5.83539803032159 2.14858601962292e-06 -0.61488397605076 3.24635280323328 -0.189407625516965 0.849844518456184 -35.1379778585065 7.34147988184958 -4.78622545099913 2.19688538210213e-06 LRRC70 other 0.0139292831652154 0.0274654610470409 1 -0.189407625516965 -4.78622545099913 2.52113953349487e-65 136.351268557614 6.88565381706885 19.8022253485374 6.61280326109786e-66 -162.406581003602 97.8891201262201 -1.65908714670427 0.0976832041804051 ANKRD46 other 3.89263943971609e-61 1 1.02432322514406e-61 19.8022253485374 -1.65908714670427 9.12585021252768e-35 137.604016065946 30.9265944615644 4.44937499461701 1.04460015297401e-05 -746.060013460188 74.3164469004728 -10.0389623640018 7.12130039171531e-22 PIP5K1C other 1.29942981176182e-30 1.10259093964928e-17 0.0939722297615422 4.44937499461701 -10.0389623640018 1.62894535016725e-17 66.8453813143171 12.6021407317688 5.304287798168 1.65171243407249e-07 -178.196867431407 31.2675683198092 -5.69909580459804 1.98103284360017e-08 ZBTB6 other 1.8135048583412e-13 0.000268112985052847 0.00166509130478847 5.304287798168 -5.69909580459804 1.6421734411076e-05 14.4627920743809 5.68922310643617 2.54213832078747 0.0112943467134881 -43.8819514573248 13.7269784751381 -3.1967669751069 0.00147064186332198 C2orf76 other 0.0979228022932464 1 1 2.54213832078747 -3.1967669751069 4.61530532147022e-05 139.981585317892 37.9397419857389 3.68957662839429 0.000247051299358234 3.01427326391651 85.2950103756736 0.0353393856292465 0.971821986302341 WWOX other 0.262703178898085 1 1 3.68957662839429 0.0353393856292465 0.314085340253158 -683.134576526003 523.167128754346 -1.30576739053262 0.192186640529396 -1327.15755262796 1096.33580673728 -1.2105392749851 0.226600627290309 CYP4Z1 other 1 1 1 -1.30576739053262 -1.2105392749851 1.54081386361332e-41 74.2717771160804 4.95965023774334 14.975204612387 1.0029451849663e-42 33.3748137237832 15.1136645013369 2.20825424044785 0.0276413338678445 CIDECP other 2.27162187912512e-37 1 1.52287196885284e-38 14.975204612387 2.20825424044785 3.42993026620943e-16 21.2213967230098 9.44661945530542 2.24645406998918 0.025077495194247 -98.9374572473694 17.4879569205306 -5.65746231517865 2.49241378592321e-08 CCDC84 essential 3.67962918958947e-12 0.000336426012823914 1 2.24645406998918 -5.65746231517865 8.48031538399607e-22 338.537473155928 79.5564605307898 4.2553108936377 2.46052178085446e-05 -781.284697130246 147.278077739331 -5.30482682231263 1.64708038040362e-07 BCL9L other 1.04053469761632e-17 0.00215866354655699 0.214803551468595 4.2553108936377 -5.30482682231263 1.22968150455492e-41 466.547952020913 41.3880759836505 11.2725209117045 1.4583795420327e-26 -316.953664636991 88.2995337881163 -3.58952817800322 0.000362095261767393 POLR1D other 1.81328834661668e-37 1 2.10808762800826e-22 11.2725209117045 -3.58952817800322 8.74771034298142e-21 137.852325491839 15.3916669583359 8.95629601816322 5.44943417949849e-18 275.775710227293 36.2194969676479 7.61401270905617 1.19808050162258e-13 KIF18B essential 1.05296189398467e-16 1.7773524241571e-09 7.32567436749982e-14 8.95629601816322 7.61401270905617 3.14143313719765e-41 153.373102916285 21.815365207365 7.03050815140629 6.16016473058254e-12 -304.538904758614 47.7369594073232 -6.37952036618184 3.78692039029162e-10 ZNRF1 other 4.62450372126866e-37 5.35470543187236e-06 7.34846050711191e-08 7.03050815140629 -6.37952036618184 0.191994152524468 5.97179321244382 3.30807991896679 1.80521431123979 0.0715939118510323 2.99639869410955 6.34069141744881 0.472566554155881 0.636711975361191 FFAR4 other 1 1 1 1.80521431123979 0.472566554155881 7.63205797150009e-13 286.368776075535 37.5584777589292 7.6246108245815 1.21241405478579e-13 291.439453288787 87.2234075944018 3.3412986413465 0.000895272546503585 SAPCD2 other 7.23824378017068e-09 1 1.50690942869326e-09 7.6246108245815 3.3412986413465 0.0105728861761247 101.736718975161 34.9391700236895 2.91182414768815 0.00374038560459605 -147.877580990475 217.762562244045 -0.679077153880793 0.497377255492455 EDARADD other 1 1 1 2.91182414768815 -0.679077153880793 0.0163203025778121 3.95093096081953 4.20856016040146 0.938784479783376 0.348256505895144 -38.0009710151964 15.9208278727102 -2.38687154455917 0.0173318505780034 CYP4F12 other 1 1 1 0.938784479783376 -2.38687154455917 4.8966695623631e-05 109.978767496535 25.4642425318257 4.31894910516508 1.86890854181707e-05 -131.732731982863 161.14237859108 -0.817492785787607 0.414010777575392 MARC1 other 0.277151497229751 1 0.164632153448666 4.31894910516508 -0.817492785787607 0.000723101038863854 5.37066729649918 6.37487206668159 0.842474521891834 0.399898152031952 -53.2203450149811 16.6881908550025 -3.18910213080574 0.00151054563886585 SOWAHB other 1 1 1 0.842474521891834 -3.18910213080574 8.02333093359583e-31 65.7597680318309 10.2030591409142 6.44510309345702 2.5519894077575e-10 -122.79252888926 19.7499001446849 -6.21737466972996 1.00888504290494e-09 BLOC1S4 other 1.10585570257751e-26 1.41304439109266e-05 2.90263275238339e-06 6.44510309345702 -6.21737466972996 6.21224691863433e-45 46.589992655795 3.00257357128454 15.51668645237 2.90418660260395e-45 2.20063237655563 15.0022708840571 0.146686617883579 0.883433426718483 ZNF749 other 9.27488464952105e-41 1 4.42568996370817e-41 15.51668645237 0.146686617883579 5.88365118190655e-12 440.061590272295 89.6576771701582 4.90824215127855 1.21763566586902e-06 -1826.12803164648 468.267377639106 -3.89975496660346 0.000108378572601867 MKL2 other 5.39471976869012e-08 1 0.0116625144076935 4.90824215127855 -3.89975496660346 0.807456116200597 0.125292125631939 1.88235045944412 0.0665615294980403 0.946955227484327 4.12539129175881 6.31301757201675 0.65347375398496 0.513727006486048 BTLA other 1 1 1 0.0665615294980403 0.65347375398496 5.3693701493652e-53 52.9238796583461 3.10366721978732 17.0520471141145 1.33545980374735e-52 -9.88862004875693 15.5745656077981 -0.634921082088208 0.525745365900032 ZNF17 other 8.16520118613966e-49 1 2.05180044247743e-48 17.0520471141145 -0.634921082088208 7.91377056590355e-18 10.5491603282673 1.49338795631404 7.06391147970993 5.06186353349294e-12 -3.23019064466331 3.02743638607905 -1.06697226059533 0.286465596442815 KDM4D other 8.89745224724536e-14 1 6.0524702269975e-08 7.06391147970993 -1.06697226059533 0.907200007050013 -6.45121013569137 16.2958244349435 -0.395881175662268 0.692355376694748 -17.2665135140684 65.5152704222083 -0.263549450422713 0.792231717657108 GPAT2 other 1 1 1 -0.395881175662268 -0.263549450422713 9.93948989073912e-21 242.297897899763 24.2148946192801 10.0061512432453 9.55675854629873e-22 220.515335027186 166.139067510092 1.3272936843334 0.184969338884892 TOR3A other 1.1942297103723e-16 1 1.33469689857608e-17 10.0061512432453 1.3272936843334 0.00671986408675674 4.06518389212889 3.87070977300145 1.05024249570038 0.294078161427336 22.3081725217729 7.08852796975283 3.14708111711814 0.00174042085800455 GABRA5 other 1 1 1 1.05024249570038 3.14708111711814 8.4764513409997e-14 443.360565176003 70.1662584974522 6.31871464533201 5.52144148149464e-10 -412.841834227407 156.503021362949 -2.63791606469999 0.00858226742691268 PPP1CC other 8.3628668930303e-10 1 6.20720451349627e-06 6.31871464533201 -2.63791606469999 1.1797788201744e-21 16.847537072374 5.5186065108189 3.05286072477633 0.00237750933045626 -85.3082920412902 11.5089817838616 -7.41232314407807 4.77825596198756e-13 ZNF555 other 1.44322343071934e-17 7.04458276475826e-09 1 3.05286072477633 -7.41232314407807 4.5863345431968e-06 3.07212511082955 3.01971224124865 1.01735690866996 0.309434258131519 -29.8116324900915 7.02358174747956 -4.24450566134431 2.57432483672802e-05 PRELID2 other 0.0287379722476711 0.302560398060644 1 1.01735690866996 -4.24450566134431 0.000168673014679455 83.6152630725547 36.5911713715248 2.28512124478267 0.0226868917117298 -108.350628942442 68.3948250654117 -1.58419337777115 0.113726606904938 BACE1 other 0.889581479419443 1 1 2.28512124478267 -1.58419337777115 0.8528552243055 91.6181227621821 542.033445139695 0.169026696754054 0.865839172691947 -424.059932927015 1104.60001859383 -0.383903608354858 0.701201565607204 THBS2 other 1 1 1 0.169026696754054 -0.383903608354858 4.71987119581794e-28 237.279507038648 69.2630273361243 3.42577441622876 0.000659260412681936 -1543.04525367526 163.334871498315 -9.44712687205422 1.01637486786489e-19 RXRA other 6.33831502886391e-24 1.56409928415728e-15 1 3.42577441622876 -9.44712687205422 4.67895479059629e-05 30.0562911786545 9.42412824434231 3.18929140174833 0.001508024385558 -29.9472384053004 19.9163105514967 -1.50365391862449 0.133248677900327 ANKRD37 other 0.265905000749587 1 1 3.18929140174833 -1.50365391862449 0.0182743465270273 1.94827038158022 3.18170945681973 0.612334472402646 0.540573763209392 -17.0174292051908 7.03054877487427 -2.4204979938419 0.0158275224999773 C9orf47 other 1 1 1 0.612334472402646 -2.4204979938419 0.0215013719581697 -504.381092063779 238.047983837956 -2.11882110460184 0.0345606561342335 -1224.59309839424 498.84733588779 -2.45484542122461 0.0144082735841086 CYP4X1 other 1 1 1 -2.11882110460184 -2.45484542122461 7.06046099777903e-39 152.57373699728 11.8680878734502 12.8557977177267 3.69044253547487e-33 -144.477319177109 51.0349548702063 -2.83094830875325 0.00481528851633174 KRT10 other 1.02877977198638e-34 1 5.48473569622276e-29 12.8557977177267 -2.83094830875325 8.80036257745702e-10 9.45550116263774 3.31531620953921 2.85206615749993 0.00451026670938707 69.8655798510965 10.8720544455761 6.42616169748168 2.88141536851119e-10 CD300E other 7.22069749480349e-06 4.08469442640146e-06 1 2.85206615749993 6.42616169748168 5.24800960263514e-08 12.5374010842542 7.18287601281322 1.74545698156133 0.0814751777627909 -82.8384051591077 17.2225410805458 -4.80988286058903 1.9626025174343e-06 CCDC30 other 0.000388247750402947 0.0245914095434517 1 1.74545698156133 -4.80988286058903 0.567041697911522 2.68287743862942 22.3259848462729 0.120168380347051 0.904394460744706 -42.6051415256369 45.9135701995508 -0.927942247585305 0.353852100467849 GLDN other 1 1 1 0.120168380347051 -0.927942247585305 7.49158839246198e-19 443.464361607938 47.0476513044411 9.4258554744491 1.26578533820196e-19 283.02189768904 177.265818450283 1.59659600572356 0.110944060527323 KPNA4 other 8.62581487508073e-15 1 1.73349302066759e-15 9.4258554744491 1.59659600572356 0.705435043864559 54.4330489999693 118.065368208335 0.461041623178765 0.644956811874841 -107.028664790402 270.844830749124 -0.395165986717833 0.692878490035006 TRDN other 1 1 1 0.461041623178765 -0.395165986717833 0.953270501018052 -0.832078556115039 2.86486322845094 -0.290442680771519 0.771587673902909 -1.54759866665102 8.64252835486398 -0.179067814776684 0.857950759585027 KRT3 other 1 1 1 -0.290442680771519 -0.179067814776684 0.0348048058317226 6.83550621814148 4.97229046879218 1.37471981193446 0.169787437675671 -12.1890879729001 9.51853698992296 -1.28056317749297 0.200895874426329 ZNF501 other 1 1 1 1.37471981193446 -1.28056317749297 3.61260553341753e-30 19.6462167209772 13.8557075404909 1.41791508398719 0.156793411069395 -269.85937141534 26.5686353237809 -10.1570655822806 2.69853509465692e-22 ZNF197 other 4.94890832022868e-26 4.18326910373716e-18 1 1.41791508398719 -10.1570655822806 0.0499917709833321 17.7932954289331 7.28940782711747 2.44097954881053 0.0149700699617317 12.2691286102682 27.1689226316083 0.451586865501772 0.651749298625591 DEFB132 other 1 1 1 2.44097954881053 0.451586865501772 9.22391738816064e-15 914.509544516295 305.988477099584 2.98870582704547 0.0029281710368999 -4172.46813855572 697.93961926424 -5.9782652014429 4.08452504272802e-09 RPS23 essential 9.43422270461071e-11 5.64195444152021e-05 1 2.98870582704547 -5.9782652014429 0.138412511891805 -19.1749318714026 30.1077180368387 -0.636877622141301 0.524472959974151 -142.82272213517 71.6928883276809 -1.99214629884044 0.0468552977159386 GNG2 other 1 1 1 -0.636877622141301 -1.99214629884044 0.0228189461218526 94.53600986216 37.7028892333337 2.50739430808871 0.0124599126117862 -64.5978910740717 153.786254283219 -0.420049837192247 0.674618958905091 BTN3A2 other 1 1 1 2.50739430808871 -0.420049837192247 0.00894134197143256 32.1681828252497 30.0207895292566 1.07153020722191 0.284407991127092 -243.622603090797 95.6229516454272 -2.5477419270026 0.01111720951967 PCLO other 1 1 1 1.07153020722191 -2.5477419270026 0.973421917951444 -0.792898800914502 11.2661390954587 -0.0703789287702041 0.943917878497418 8.27676770378019 41.0230117204326 0.201759143384827 0.840180307544264 KLK12 other 1 1 1 -0.0703789287702041 0.201759143384827 0.000813824744612452 296.272771431735 94.5810202219292 3.13247595274979 0.00182684221195917 -278.232937179506 293.058827829288 -0.949409847983085 0.342834558797766 INSIG1 other 1 1 1 3.13247595274979 -0.949409847983085 0.445998339732887 8.71667755635409 76.5353205821992 0.113890913241715 0.909367725848966 -437.10834461194 353.019063754282 -1.23820039621483 0.216194103721137 C5orf38 other 1 1 1 0.113890913241715 -1.23820039621483 4.85006226674853e-20 12.7866995294646 7.59226782713564 1.68417392808029 0.0927248642124651 -137.166269800054 16.4859537045229 -8.32019016057424 7.18487768053593e-16 ZNF396 other 5.74877880477703e-16 1.08577871508259e-11 1 1.68417392808029 -8.32019016057424 6.14199658103464e-16 -11.4378185263282 36.9181299174777 -0.309815761304673 0.756820585884069 -433.387844181191 57.666874949721 -7.51536899752338 2.37308805348123e-13 TMEM222 other 6.53569856187896e-12 3.50932261348804e-09 1 -0.309815761304673 -7.51536899752338 0.705365381525385 1.87700303739949 2.43418977056562 0.771099714614008 0.440988880340275 2.66804227283828 4.02765140921866 0.662431278618491 0.507980654601103 CLCNKA other 1 1 1 0.771099714614008 0.662431278618491 0.488376001051942 12.2840713992683 11.4588947340498 1.07201188983494 0.284196224356995 67.9370034111505 129.617646018561 0.524133908445015 0.600401667296816 ARHGAP30 other 1 1 1 1.07201188983494 0.524133908445015 0.000406019201566171 33.3858049343063 36.3428092947356 0.918635779186789 0.358693981343752 -381.500190248885 106.342544160446 -3.58746532971121 0.000364080366924044 SEPT10 other 1 1 1 0.918635779186789 -3.58746532971121 0.133684509125238 -152.366440501044 110.255521447514 -1.38193932150215 0.167555450654115 -737.079331941545 417.092571349708 -1.76718403196768 0.0777559777253885 CYP4F8 other 1 1 1 -1.38193932150215 -1.76718403196768 0.951055133640064 3.01569233383503 9.52990607464892 0.316445126553477 0.751785612253935 2.41409752229285 36.0512832120493 0.066962873640126 0.946635772059786 CYP4F3 other 1 1 1 0.316445126553477 0.066962873640126 4.25183307994081e-37 47.2873634538842 7.49971234905879 6.30522362098577 5.95775705386215e-10 -120.449576827259 13.7681853131162 -8.74839886942203 2.71321783454173e-17 SMYD4 other 6.13879660081855e-33 4.13521530162506e-13 6.6905611714872e-06 6.30522362098577 -8.74839886942203 0.943640935062543 -1.67721410630173 6.00630514518508 -0.279242240572186 0.780165057829284 1.06018706356883 12.360247888172 0.0857739321379924 0.931677688130328 FOXD2 other 1 1 1 -0.279242240572186 0.0857739321379924 2.44593314968404e-25 216.28570864341 28.5413145168713 7.57798693944385 1.54436814632202e-13 -305.916108876915 66.7898485132369 -4.58027852565477 5.77550070926447e-06 GPATCH8 other 3.17433204165995e-21 0.0707152306842342 1.9154798118832e-09 7.57798693944385 -4.58027852565477 3.29386812668015e-12 52.0434528030012 7.94865368823111 6.54745505896898 1.35000952161246e-10 139.499900256866 26.3170611486133 5.30074005866785 1.67578578596191e-07 CEACAM19 other 3.05275697980716e-08 0.00219527937961011 1.54927092700246e-06 6.54745505896898 5.30074005866785 5.85494102636044e-42 264.462211532246 24.9731782037613 10.58985001326 6.07791483264405e-24 -237.076920760578 51.925568741847 -4.56570677038182 6.1682805251756e-06 NF2 ts 8.64891888413965e-38 0.0754072294202717 8.65008838981902e-20 10.58985001326 -4.56570677038182 5.02139230686285e-34 985.800125582995 97.6052172402188 10.0998712308259 4.25503784929567e-22 -1918.82778130971 361.412907846995 -5.30923976329602 1.60636960225874e-07 UBE2H other 7.11280220267123e-30 0.00210675373336234 5.95960601172351e-18 10.0998712308259 -5.30923976329602 0.00380398200497856 33.1294110387887 11.2353844762549 2.94866732053586 0.0033283640359615 -13.7659433065462 24.2063841463128 -0.568690607541362 0.56980038100209 HPDL other 1 1 1 2.94866732053586 -0.568690607541362 1.0204880380947e-12 4.8882503419411 4.49345615303629 1.08785980667421 0.277142300489481 -66.0408515420996 9.85800340662274 -6.69921167786699 5.27585317335135e-11 KTN1-AS1 other 9.63953000784256e-09 7.5755975716152e-07 1 1.08785980667421 -6.69921167786699 5.32269409729841e-26 71.1366483933334 8.75954088836394 8.12104758684675 3.11344091465557e-15 -83.2645753283565 21.878711887182 -3.80573480549092 0.000157440981394414 KATNA1 other 6.97858423096794e-22 1 3.99703544623481e-11 8.12104758684675 -3.80573480549092 0.114041584351333 18.5280005736569 9.8291484531722 1.88500567082973 0.0599738417528383 -6.22513418721042 20.7400176427586 -0.300150862667368 0.764179329874065 FSD2 other 1 1 1 1.88500567082973 -0.300150862667368 3.08458652982693e-19 445.031963838552 57.8513019740556 7.6926870900526 7.87446290673571e-14 -419.077635730642 171.573459147957 -2.44255514700119 0.0149331017760654 ARAP1 other 3.58984180341258e-15 1 9.82969204647819e-10 7.6926870900526 -2.44255514700119 3.90381008344205e-18 60.8469340586561 8.63544386188416 7.04618489007002 5.6102481923273e-12 -77.5419726917141 22.8179695427552 -3.39828539723571 0.000727940786169965 KIF24 other 4.42028415748144e-14 1 6.69975839127726e-08 7.04618489007002 -3.39828539723571 0.457327217486678 11.9017727967345 19.9441661612918 0.596754594826519 0.55094572734363 -47.1449399468457 59.7542624334847 -0.78898036770724 0.430503501892869 PDE2A other 1 1 1 0.596754594826519 -0.78898036770724 0.095161219755334 8.34240936378145 4.52784398917532 1.84246837650007 0.0659557008935598 -9.02512727706679 14.2428666238441 -0.633659467256242 0.526571874007584 CARMIL3 other 1 1 1 1.84246837650007 -0.633659467256242 0.0106214165917375 4.66315925540668 1.72447963167499 2.70409645307167 0.00707125480060147 -0.594262170535085 4.4615458361215 -0.133196473232176 0.894089037929622 PRG2 other 1 1 1 2.70409645307167 -0.133196473232176 3.79091475144338e-07 64.2297622441071 15.808307996518 4.06303838831168 5.55451509993976e-05 -39.8472199874467 31.5836594415084 -1.26164037644979 0.207616936996225 PRR5 other 0.00262520846537454 1 0.470189703209901 4.06303838831168 -1.26164037644979 2.04706996252325e-14 167.479136354275 43.9941404909848 3.80685096890562 0.00015687382332261 -521.636700273615 108.533466139653 -4.80622907226065 1.99634853580813e-06 ZFP91 other 2.06672183416347e-10 0.0249982763653894 1 3.80685096890562 -4.80622907226065 1.51290277000704e-39 212.803762441874 17.4445426757077 12.1988731030601 2.72972239765583e-30 -473.036459061098 79.2949933670385 -5.96552744347325 4.50084364770153e-09 C17orf58 other 2.21125868864228e-35 6.21116423382811e-05 4.01705948039032e-26 12.1988731030601 -5.96552744347325 1.04952392966647e-19 26.5001473110555 7.00575952714992 3.78262302729028 0.000172490667217305 -155.74200258894 20.4989116990637 -7.59757419688059 1.33689461466574e-13 BCDIN3D other 1.23581442718227e-15 1.98234733462636e-09 1 3.78262302729028 -7.59757419688059 0.00475689066994207 17.9938680721756 7.5019564946228 2.39855670784989 0.0167980416515807 51.0700737036728 17.7823346240593 2.87195549872151 0.0042396716234968 CYP27C1 other 1 1 1 2.39855670784989 2.87195549872151 1.07463313858781e-15 59.3770023614473 11.5994704214472 5.11894079678504 4.26430719530446e-07 -118.551949858539 27.2921834562466 -4.34380598564403 1.6698705402407e-05 LYRM7 other 1.13492005766258e-11 0.199015170985887 0.00420375403313114 5.11894079678504 -4.34380598564403 6.97350941945287e-06 43.6945475349944 14.6169189827249 2.98931310946139 0.00292339931699018 -90.4325860304321 32.0536410901776 -2.82128903159597 0.00495915202383803 CFAP73 other 0.0429568180238297 1 1 2.98931310946139 -2.82128903159597 7.5869952140292e-14 69.7439554831663 9.76993109554203 7.13863330264326 3.08176199859906e-12 -96.0577813554415 43.991415449206 -2.18355741397667 0.029427665892891 CCDC73 other 7.49670997098225e-10 1 3.7055106271155e-08 7.13863330264326 -2.18355741397667 7.84348033735425e-36 407.902022082032 44.4092309160915 9.1850728703845 8.50582966852944e-19 -450.224972699685 99.5904209632048 -4.52076583616438 7.56092242646211e-06 BCR other 1.12585316762383e-31 0.0919786213179115 1.15475143579956e-14 9.1850728703845 -4.52076583616438 0.150910051886749 3.51032192757783 5.07918618734927 0.69111897026358 0.489783968389297 -12.7455159578059 10.100786732321 -1.26183398338885 0.207546315743428 MPPED1 other 1 1 1 0.69111897026358 -1.26183398338885 1.27224974003616e-16 4.91089296705463 1.2930312662261 3.79796923348016 0.000162674245432256 -26.1904799040109 3.63174093987445 -7.21154959497643 1.90746240519733e-12 FSCN2 other 1.38166321767927e-12 2.79500466233565e-08 1 3.79796923348016 -7.21154959497643 0.354806170773605 -24.5781429265419 25.1956544292152 -0.975491348938438 0.329749368130171 -69.4387913295275 51.4008168206461 -1.35092777945186 0.177279148658724 FOXI2 other 1 1 1 -0.975491348938438 -1.35092777945186 6.95700742489972e-07 7.52069720237124 1.39234615781442 5.40145649855963 1.02751188181449e-07 7.02287464593318 3.08993860677701 2.27282012352292 0.0234639845858905 ZNF732 other 0.00471476393185454 1 0.00104826762182714 5.40145649855963 2.27282012352292 0.00112608736589733 17.7485815733855 7.18604547196028 2.46986769602835 0.0138331746111828 -16.3464071420429 13.2159676456354 -1.2368679751907 0.21668908744354 HYAL3 other 1 1 1 2.46986769602835 -1.2368679751907 0.276183479616399 12.3036359342004 8.27430746302496 1.48696866646316 0.137599259300468 29.3112066229678 33.4146976259457 0.8771950281007 0.380765807505331 VSIG10L other 1 1 1 1.48696866646316 0.8771950281007 3.46445169115787e-32 193.022065874971 25.4792659836013 7.57565253250239 1.55766452747596e-13 -374.370698580482 55.3260249763016 -6.76662924438978 3.43445631164716e-11 ZNF397 other 4.83637456085639e-28 4.94699087129657e-07 1.93165978052293e-09 7.57565253250239 -6.76662924438978 3.83031548501279e-28 72.6088236612138 13.4181171722505 5.41125276587785 9.41606108041463e-08 -226.474735432509 29.1362822729929 -7.7729455429677 3.88829619925649e-14 ZSCAN30 other 5.14756098030869e-24 5.79239484803239e-10 0.000963733851580437 5.41125276587785 -7.7729455429677 2.68597126318872e-14 32.0972967581673 44.2562618834434 0.725260005978388 0.468605543049504 -740.975483698265 98.7613035954983 -7.50269039312316 2.57784781210702e-13 TPCN1 other 2.69886392525203e-10 3.81005906629417e-09 1 0.725260005978388 -7.50269039312316 0.939208764277197 4.27342200451882 15.0137689968719 0.284633525759534 0.776032844691752 -13.0573033025654 77.4190219314518 -0.168657559561093 0.866128462157721 LILRB4 other 1 1 1 0.284633525759534 -0.168657559561093 0.61632760075488 1.2672980191697 5.74123228765595 0.220736238436908 0.825384620956963 -8.09151998923174 10.7379149562459 -0.753546663593677 0.451463186280972 TNFRSF4 other 1 1 1 0.220736238436908 -0.753546663593677 0.000403272127147574 218.358211305895 218.594521448704 0.99891895670009 0.31827888373038 2277.2103690969 574.591286246705 3.96318291558492 8.38375461870217e-05 KRT16 other 1 0.95004707339133 1 0.99891895670009 3.96318291558492 2.03040527084908e-46 221.157054238647 49.3552614133577 4.48092154525175 9.09820392419947e-06 -1497.39682824584 119.553760458321 -12.5248827180795 9.8043530213169e-32 HEXIM1 other 3.04195317678609e-42 1.5351655960778e-27 0.0822659598826116 4.48092154525175 -12.5248827180795 0.137984929397685 866.795855196688 755.578224648757 1.14719538880257 0.251806090177644 3840.07781906523 1993.067283152 1.92671760332758 0.054536353568242 KRT14 other 1 1 1 1.14719538880257 1.92671760332758 0.000139482151660295 19.997689949744 6.09720727784778 3.27981140191824 0.00110510704689829 -13.3718622297814 11.6562178249026 -1.14718705764176 0.251807676560439 PDZD7 other 0.74371883265269 1 1 3.27981140191824 -1.14718705764176 1.1970312419531e-10 91.830393815906 16.5147891786717 5.56049446483409 4.22841989829067e-08 -128.481098578242 47.2848298572202 -2.7171737524741 0.00679472829538742 POFUT2 other 1.02765132121674e-06 1 0.000440474500804939 5.56049446483409 -2.7171737524741 2.42295031621987e-33 428.624751816471 173.751044322036 2.46689021921528 0.0139419832565633 -4544.83644302262 414.793052539053 -10.9568769660016 2.43998084871704e-25 MAPT other 3.41635994587001e-29 3.80075816804654e-21 1 2.46689021921528 -10.9568769660016 1.0164724373699e-14 21.7438194435503 2.644809812652 8.22131683704975 1.49513092565043e-15 4.35198079077133 9.56344942248131 0.455063920821382 0.649245476415819 TMEM17 other 1.03761506406719e-10 1 1.92991499882958e-11 8.22131683704975 0.455063920821382 0.0452665170487611 18.5230565537357 31.6741778851505 0.584799915593694 0.558936397293875 -112.18453301489 59.2407015425975 -1.89370703070123 0.0588197612172635 TNFRSF18 other 1 1 1 0.584799915593694 -1.89370703070123 1.999252982133e-07 -1.63641982636883 4.65178245334182 -0.351783395458064 0.725137941934181 76.3789754820827 14.3319178417066 5.32929202676672 1.45060032856189e-07 C1QL4 other 0.00141407163426267 0.00190710425196031 1 -0.351783395458064 5.32929202676672 0.000365427395956951 33.9638387232868 9.39330864196299 3.61574819031914 0.000328593112483479 -2.3726601348077 24.4966081512486 -0.096856679919043 0.922877457863767 RTN4RL2 other 1 1 1 3.61574819031914 -0.096856679919043 2.40459033900495e-18 129.145780476831 18.0087190823211 7.17129185515543 2.52832238267922e-12 -244.311829555773 55.9331908438267 -4.36792226350766 1.51085715112434e-05 ZDHHC17 other 2.73834747805884e-14 0.18044166955878 3.04662847112846e-08 7.17129185515543 -4.36792226350766 6.13918732692579e-09 102.743845620962 44.8360594747325 2.29154494896822 0.0223110730304153 -410.807232261305 92.8264708345699 -4.42553970400773 1.16157907269749e-05 SERPINA11 other 4.81189502684443e-05 0.139645036119693 1 2.29154494896822 -4.42553970400773 2.43652686521618e-54 292.408266887188 65.4716202975615 4.4661834480073 9.69543665004582e-06 -1425.3173872023 134.599054909126 -10.5893565758288 6.05294588129279e-24 ZNF395 other 3.71131772109729e-50 9.40930437246965e-20 0.0874625340200633 4.4661834480073 -10.5893565758288 5.12915313910161e-51 388.711235077479 25.7316402504972 15.1063527739926 2.76039775509823e-43 -411.559692300943 90.146244223081 -4.56546687937962 6.17269413999821e-06 ZACN other 7.77169283636676e-47 0.0754550131673381 4.19580458774931e-39 15.1063527739926 -4.56546687937962 1.23977153139339e-08 145.615150652912 24.1787278634708 6.02244880190355 3.17480270907145e-09 91.77356207994 47.2616656403602 1.94181819105351 0.0526778614961376 PPARA other 9.53136353335239e-05 1 3.46370975559695e-05 6.02244880190355 1.94181819105351 4.95982852448504e-11 4.00893176910045 2.33782787211215 1.71481049435796 0.0869484425611504 -29.2572663558116 5.18739340183537 -5.64007085821946 2.73294090935292e-08 TMEM232 other 4.34232987318665e-07 0.000368509752217148 1 1.71481049435796 -5.64007085821946 0.19244320737236 0.668022978231409 3.34267117131633 0.199847051652509 0.841675158309696 -12.4589872738062 7.54650040991814 -1.65096224700812 0.099325550861692 FAM183A other 1 1 1 0.199847051652509 -1.65096224700812 3.57576981735505e-20 -10.0149307525957 3.39392438247441 -2.95084086266358 0.00330489956144873 -65.2533221829283 6.74936990071026 -9.66806133651994 1.61435318304425e-20 EFCAB6 other 4.24837211999953e-16 2.49030122016407e-16 1 -2.95084086266358 -9.66806133651994 6.86273308966446e-05 -9.02669807506137 6.79841550123006 -1.32776498780166 0.184815706717042 -82.2266140299845 18.6197796778279 -4.41608952698287 1.2141329069054e-05 KANK3 other 0.381224823130861 0.145829503448407 1 -1.32776498780166 -4.41608952698287 0.00774691456857722 83.775719732602 30.133744534533 2.78012975243072 0.00562396551044141 3.34158896695227 57.8764689761396 0.0577365728432723 0.95397989859724 EMID1 other 1 1 1 2.78012975243072 0.0577365728432723 1.35687279825775e-06 56.0075757084179 58.8873209054307 0.951097364377682 0.34198044253018 -384.262359057214 95.6738252937105 -4.01637917034844 6.74747084683326e-05 ESPN other 0.00895536046850118 0.770291271874485 1 0.951097364377682 -4.01637917034844 1.2446396407343e-08 43.549345966182 14.2754082841815 3.05065502150567 0.00239557825614231 -130.116037444637 32.6040984350668 -3.99078777484897 7.49516344101013e-05 PTRH1 other 9.56754491832456e-05 0.852724744683723 1 3.05065502150567 -3.99078777484897 0.320293051647849 5.31948485439369 3.71945096178692 1.43018012847737 0.153238361679071 -1.3725639517834 14.0940032609058 -0.0973863796094502 0.92245536396787 GPR141 other 1 1 1 1.43018012847737 -0.0973863796094502 7.75275615340513e-06 -38.4946430737715 26.7087651196202 -1.44127378788821 0.150081653421946 -263.253392797789 54.6077287396381 -4.82080831548486 1.85704705639166e-06 TMPRSS6 other 0.0475941700257541 0.0232892271342079 1 -1.44127378788821 -4.82080831548486 1.49262302111438e-18 48.0224967700769 9.3660790525741 5.12727860831783 4.15924461642209e-07 -133.505876290515 24.8030877608843 -5.38263129081293 1.11435820245965e-07 TMEM216 other 1.7069636869464e-14 0.00147251292873019 0.00410309481410039 5.12727860831783 -5.38263129081293 1.09106017091512e-07 167.166502497922 46.9009014697135 3.56424924168826 0.000396932620807286 -226.013809436213 97.0153869340737 -2.32966972125565 0.020187967850111 RPS19BP1 essential 0.00078741812534944 1 1 3.56424924168826 -2.32966972125565 1.98457456694552e-12 93.6330424195748 20.6429903686 4.53582745269308 7.12211257879099e-06 -189.902603012623 49.8231243708112 -3.81153541474563 0.000154543611502979 TMEM262 other 1.85339418807043e-08 1 0.0648753234802071 4.53582745269308 -3.81153541474563 0.0245275408083747 29.247338691697 11.1276509151954 2.62834796980898 0.00882246492670976 -31.5801830378307 46.0845526012679 -0.685266130520314 0.493467888980706 C3orf70 other 1 1 1 2.62834796980898 -0.685266130520314 0.0426262247054918 135.469819102885 68.2681715635305 1.98437743387951 0.0477204474727343 -100.158239007802 154.507783860763 -0.648240732635591 0.517105310992977 TEAD1 other 1 1 1 1.98437743387951 -0.648240732635591 1.44856649237944e-05 85.3898947107976 24.0612056380471 3.54886184820987 0.00042049184530151 -69.4602024670989 48.2634640786905 -1.43918808550187 0.150674490615782 PLCD1 other 0.0868995038778427 1 1 3.54886184820987 -1.43918808550187 2.60879922815026e-07 -318.467437111409 183.659431052759 -1.73401080078444 0.0834806100306027 -2003.10024527653 362.205049662662 -5.53029353716108 4.96309079006095e-08 ENTPD5 other 0.00182850737901052 0.000663465976815347 1 -1.73401080078444 -5.53029353716108 0.00612027566034862 -0.528232354937319 19.931414801105 -0.0265025017144309 0.978866383855519 -112.289464201855 38.9103921386894 -2.88584766253752 0.00406059670197521 MITF og 1 1 1 -0.0265025017144309 -2.88584766253752 2.62141157871126e-11 8.81618931547882 2.50935974892514 3.51332220071481 0.000479430592891177 -20.0251204361952 4.94184170936812 -4.05215739675233 5.8156463081294e-05 HEATR4 other 2.32886204652708e-07 0.66740357032093 1 3.51332220071481 -4.05215739675233 4.59174018378156e-09 1069.84786989771 185.361702634023 5.77167696830025 1.33819179920526e-08 -725.250146643504 575.207475025039 -1.26084965535598 0.207918817570058 NAP1L1 other 3.62701557116906e-05 1 0.000142570954287329 5.77167696830025 -1.26084965535598 0.022526068278799 2.41813347230691 1.29193203888714 1.87171878978237 0.0617889049337069 12.8944077500636 5.45877004130214 2.36214525479219 0.0185253031600245 LILRA5 other 1 1 1 1.87171878978237 2.36214525479219 3.91830343205073e-41 128.795425971047 17.2728544099049 7.45652240877981 3.57003309378593e-13 -335.965706565012 35.5154665748506 -9.45970133482402 9.4846622540768e-20 CMC1 other 5.76578350026265e-37 1.45968952090242e-15 4.38685666564415e-09 7.45652240877981 -9.45970133482402 0.154355092988364 94.998863773772 59.995908233196 1.58342237948168 0.113904246625559 -45.0596212490093 115.997987844492 -0.388451748916686 0.697833174017617 SLIT1 other 1 1 1 1.58342237948168 -0.388451748916686 2.5856704484008e-05 -144.480600108869 59.5268211401647 -2.42715127973436 0.0155501267670614 -637.597349786513 140.611245636243 -4.53446910950464 7.14644253325142e-06 LYPD6 other 0.150977297482123 0.0870651093826021 1 -2.42715127973436 -4.53446910950464 0.60831765809089 13.1702094497598 92.4036355785381 0.142529126341201 0.886715041725031 402.562824432231 403.601099719739 0.997427471609396 0.319002147712558 AKR1C1 other 1 1 1 0.142529126341201 0.997427471609396 0.0981227143805085 3.96572765171665 2.36664820029613 1.67567264590506 0.0943801341423435 -3.19643467342411 4.66171453504698 -0.685677908716453 0.493209953402799 FOXD3 other 1 1 1 1.67567264590506 -0.685677908716453 1.72704503448478e-24 92.4493915143043 21.7935707609752 4.24204883762553 2.60251411791517e-05 -212.580584579099 33.6699528103811 -6.31365852445022 5.65554567747414e-10 SPATA21 other 2.21476255222329e-20 7.96809830499332e-06 0.226574879105695 4.24204883762553 -6.31365852445022 2.67741044068537e-20 204.638279956218 34.9877191185137 5.84886026045448 8.53967173955828e-09 -432.203613241542 76.8491144702439 -5.62405456745883 2.98366769820695e-08 RNF220 other 3.19013454007662e-16 0.000401840365594512 9.16477571089394e-05 5.84886026045448 -5.62405456745883 2.14335958846021e-14 202.748838085634 58.8871600495918 3.44300587623667 0.000619742941584863 -628.428265060697 111.994660171263 -5.61123417937695 3.20831881423764e-08 SHTN1 other 2.16136380900328e-10 0.000431390547762393 1 3.44300587623667 -5.61123417937695 2.84381824265283e-13 9.87129644703099 2.32552909612346 4.24475293105811 2.57083605950003e-05 -73.9609444430057 13.4907194279208 -5.48235732261497 6.41792771200899e-08 ZNF546 other 2.74883471334823e-09 0.000854803791962477 0.223996945864237 4.24475293105811 -5.48235732261497 4.5482638060367e-25 171.772142256858 19.9408766698446 8.61407174322576 7.91084696326471e-17 -201.129982996743 62.4342110330045 -3.22147072364572 0.00135275552733115 TSPYL4 other 5.87908579568304e-21 1 1.04502288384727e-12 8.61407174322576 -3.22147072364572 0.0484570942926226 -62.5970752065054 124.115116200081 -0.504346908926026 0.614224489660858 -583.391051620735 265.046121344548 -2.20109258215612 0.0281542217583759 MT1X other 1 1 1 -0.504346908926026 -2.20109258215612 0.000579709217871094 218.616452442158 71.452755734051 3.05959441586625 0.00232519413200306 -211.542018644025 160.05128010997 -1.32171400627771 0.186816912433925 GCNT1 other 1 1 1 3.05959441586625 -1.32171400627771 0.000530349910442572 200.156299123184 96.0044359492369 2.08486511216021 0.0375533489666299 -668.592313176415 254.252727636515 -2.62963673739716 0.00879269190658443 SESTD1 other 1 1 1 2.08486511216021 -2.62963673739716 0.00016282970276986 157.645000353062 43.1784519226083 3.65101094026297 0.000286622488703498 -70.4050093526325 95.7712461857545 -0.735137237496914 0.462575060856916 FNBP1 other 0.860717808841483 1 1 3.65101094026297 -0.735137237496914 7.58126694639929e-11 -58.1957589713209 37.6494463399691 -1.54572682014555 0.122756375516816 -495.843886134151 76.3166545653418 -6.49719106475785 1.86102959460055e-10 DYNC2H1 other 6.5828140895585e-07 2.64712849535982e-06 1 -1.54572682014555 -6.49719106475785 0.00144149492939395 0.470442358090184 0.167466825936454 2.80916746023893 0.00514760988116822 2.16252417056996 0.723765989575143 2.98787757606486 0.0029374178886191 KRT12 other 1 1 1 2.80916746023893 2.98787757606486 1.64194059515937e-06 280.593461965806 385.378168117331 0.728099008141991 0.466865110117593 -6050.12239700917 1274.126984804 -4.74844538194901 2.62278493785421e-06 BCAM other 0.0107530689576987 0.0326799003256634 1 0.728099008141991 -4.74844538194901 2.53113465490943e-14 67.4734965866432 23.6738566553287 2.85012693829317 0.00453650665860218 -536.745892879196 79.5738798081484 -6.74525226334676 3.92820029311961e-11 RSBN1L other 2.54682768976987e-10 5.65307304182843e-07 1 2.85012693829317 -6.74525226334676 1.14247430666658e-07 12.4466208779727 6.44461624091957 1.93132071991252 0.0539625529487724 -88.1561931165698 19.8017535712265 -4.45193870328068 1.03299559900121e-05 WDR86 other 0.000822924243091936 0.124641248975486 1 1.93132071991252 -4.45193870328068 7.4587248848673e-08 13.6337823963448 6.30862749258354 2.16113289497164 0.0311231438330594 -98.2030065754164 21.195443475525 -4.63321310963907 4.51599245411277e-06 EPOR other 0.000544486916595313 0.0556054150874905 1 2.16113289497164 -4.63321310963907 0.340446289240466 135.921213038985 95.6372597806508 1.42121609664191 0.155830096166379 157.273763217641 291.712218134496 0.53914013003435 0.590011962828603 CIDEC other 1 1 1 1.42121609664191 0.53914013003435 0.130908788123119 13.303704578308 9.2608773613729 1.43654905028736 0.151426331592494 -18.3655533911711 22.5460202327009 -0.814580719861754 0.4156721001761 PCDHB13 other 1 1 1 1.43654905028736 -0.814580719861754 0.111206412303192 -52.6029744047265 35.9775324133128 -1.46210623342422 0.144290591751029 -215.946678721603 118.789143672566 -1.81789911136025 0.0696304553421656 MAGI2 other 1 1 1 -1.46210623342422 -1.81789911136025 0.434371996170863 8.55705079742565 8.5110689748433 1.00540259075778 0.315158388864114 -9.31400785848352 22.0391229542888 -0.422612455032882 0.672748154663212 LUZP2 other 1 1 1 1.00540259075778 -0.422612455032882 5.99982578256013e-23 280.119800046477 94.5644976367637 2.96220893725316 0.0031881503306929 -1209.48218634253 162.030694278255 -7.46452511192407 3.34637154611045e-13 CHP1 other 7.51358182750005e-19 4.9415868621413e-09 1 2.96220893725316 -7.46452511192407 0.105008986456221 38.9809943756003 28.4202041125189 1.37159445517245 0.170757237102735 218.225233427479 119.446650558863 1.82696821054801 0.0682543321092121 FPR3 other 1 1 1 1.37159445517245 1.82696821054801 0.42682761717765 -26.8651098352054 23.544108937254 -1.14105443135699 0.254362585583945 12.3429724943046 61.9942961309045 0.199098518164344 0.842262036136315 C11orf96 other 1 1 1 -1.14105443135699 0.199098518164344 6.61309964208409e-11 79.0182271889983 24.257387490339 3.25749123727644 0.00119463246968866 -276.962935963889 60.8589856380029 -4.55089635590216 6.60409191563791e-06 KCNJ11 other 5.75802585836262e-07 0.0806029418303607 1 3.25749123727644 -4.55089635590216 2.09246844335982e-05 1.7857223682801 2.95564703151827 0.604173079274222 0.545988080354568 -20.1502175640802 5.34839262147349 -3.76752773967607 0.000183434343403733 CDHR4 other 0.123413788789362 1 1 0.604173079274222 -3.76752773967607 0.000773392633727772 1594.81700378424 430.100953631856 3.70800620253755 0.000230527257681664 2131.57074347112 1013.91438280123 2.10231828212364 0.0359886714122752 COL4A1 other 1 1 1 3.70800620253755 2.10231828212364 0.0150430814396296 -43.1497589640236 18.3762839783738 -2.34812212386381 0.0192274823576872 -84.0351858879716 33.08773716107 -2.53976829781049 0.0113712703523832 GJA4 other 1 1 1 -2.34812212386381 -2.53976829781049 1.01410518565376e-24 207.136655729628 18.756697909505 11.0433433821345 1.02126096609486e-25 192.80623334411 74.8206565418517 2.57691180825527 0.010231554387946 HSPA14 essential 1.30555901601065e-20 1 1.46887964753423e-21 11.0433433821345 2.57691180825527 1.79006716659424e-05 58.3895001312646 12.400753485256 4.70854454132059 3.17165116483291e-06 -25.0489686338451 55.2316270058121 -0.453525814678773 0.65035134868305 ATP13A5 other 0.106418437162797 1 0.0295693038097372 4.70854454132059 -0.453525814678773 2.2146122779774e-23 117.778917786223 11.4123912788963 10.3202663585518 7.11931582763006e-23 -32.7692450993824 32.1166077243575 -1.0203208688983 0.308042695225222 SIRT7 other 2.79063293147932e-19 1 1.00432188380377e-18 10.3202663585518 -1.0203208688983 0.0569257967836813 -12.1131405350098 63.4471082232627 -0.190917141446149 0.848662266717615 387.601948778269 177.486772767906 2.1838356894636 0.0294038767279465 PRR27 other 1 1 1 -0.190917141446149 2.1838356894636 4.521476587139e-21 339.248039626533 40.4508704412353 8.38666846784852 4.34740140563504e-16 -470.779099461924 183.468196851577 -2.56599839939985 0.0105555659705535 IFT140 other 5.47189096575561e-17 1 5.66596825196414e-12 8.38666846784852 -2.56599839939985 0.0054673034626646 -0.205310313807695 1.07887740605952 -0.190299947570102 0.84914534756532 -10.3096331012104 3.31494994028252 -3.11004186697666 0.00196896887979594 POTEG other 1 1 1 -0.190299947570102 -3.11004186697666 1.1520635574272e-12 84.4175383133536 11.3238546508712 7.45484121052884 3.63795623335286e-13 172.113342326201 70.5371747987072 2.44003736777611 0.0150087296823152 TLR5 other 1.08605031558663e-08 1 4.46959302829732e-09 7.45484121052884 2.44003736777611 4.69547146822459e-38 772.17068578796 64.4693176548563 11.9773361015214 1.80842073006213e-29 -1186.89451005967 321.889768408177 -3.68727007363158 0.000249678663219131 USP7 essential 6.81782457186211e-34 1 2.65204900063611e-25 11.9773361015214 -3.68727007363158 1.73909301836363e-18 23.1168613560893 2.65761001185636 8.69836479128177 4.08356868395535e-17 -11.0161020859463 9.61380016143339 -1.14586343599468 0.252360137626878 NHLRC1 other 1.98656595487677e-14 1 5.42012071421394e-13 8.69836479128177 -1.14586343599468 8.89950220093649e-08 10.7495911786288 6.99072010948945 1.53769440204549 0.124736305052327 -55.6185246967023 13.0172069762466 -4.27269265966141 2.30017905744309e-05 PLEKHN1 other 0.000645747879699952 0.271329121615987 1 1.53769440204549 -4.27269265966141 3.36010414510239e-14 24.8547278983063 3.63216357970556 6.84295389039751 2.12625709723449e-11 -8.99032453555686 8.2261553940884 -1.09289505301804 0.274930828428539 ZNF385C other 3.36749637422162e-10 1 2.49877734066997e-07 6.84295389039751 -1.09289505301804 1.35350013460443e-11 276.55403390835 40.8443331767737 6.77092787171791 3.33049815149453e-11 -204.696573775648 138.886745395418 -1.47383807715319 0.141104667007856 TET3 other 1.2184208211709e-07 1 3.89002184094561e-07 6.77092787171791 -1.47383807715319 3.74081666550661e-13 110.309188924947 14.9445187168539 7.38124733321415 5.96453167037789e-13 32.217258628456 27.0387868206094 1.19152012411664 0.233972878536482 ZNF286A other 3.5938025705522e-09 1 7.28567543536659e-09 7.38124733321415 1.19152012411664 0.0843575869706992 1071.38454515558 512.693219018024 2.0897185790903 0.0371312109166189 245.765115429259 954.265135107569 0.257543848546406 0.796861445349306 ISG15 other 1 1 1 2.0897185790903 0.257543848546406 0.000214408105756217 26.0664649634044 15.0102687058702 1.73657550535457 0.0830743643808281 -105.346345448085 35.0052460529984 -3.00944450693445 0.00274857274453642 EXD3 other 1 1 1 1.73657550535457 -3.00944450693445 0.555433392048612 2.98208778251269 3.69998765424466 0.805972360229799 0.420610309783202 7.52712526281341 7.65424380658264 0.983392409886407 0.32585069602794 TCL6 other 1 1 1 0.805972360229799 0.983392409886407 8.76043758352535e-42 19.1294821504738 9.74334211905911 1.96333885403185 0.0501292606607681 -223.637263161417 17.7840311766736 -12.5751726894604 6.39469593634347e-32 C17orf97 other 1.29295298295251e-37 1.00140938363139e-27 1 1.96333885403185 -12.5751726894604 4.96392384434679e-16 14.7941264113254 2.99424638214174 4.94085139404707 1.03749134043854e-06 -56.2986207603906 10.6654458891069 -5.27859982093115 1.88522084503346e-07 ZKSCAN4 other 5.29452117238028e-12 0.00246285251195171 0.00997029178161435 4.94085139404707 -5.27859982093115 0.210212687977222 18.0345366032884 13.5767289618309 1.3283418011798 0.184641254913605 -51.2951902715611 53.9741975381227 -0.950365037578014 0.342363260614246 RGPD1 other 1 1 1 1.3283418011798 -0.950365037578014 2.64529577629634e-14 95.056067357647 20.6409917003167 4.60520835131136 5.13791353515499e-06 -341.696019547161 65.3732860898744 -5.2268447860706 2.4633475348743e-07 DHRS4L2 other 2.65825772560019e-10 0.00320506147762495 0.0472688045234259 4.60520835131136 -5.2268447860706 0.0218564277867129 56.3885728255656 37.6874170967751 1.49621749563705 0.135221664838345 -126.444846591939 83.2136772750294 -1.51951999638264 0.129257467692785 SAMD11 other 1 1 1 1.49621749563705 -1.51951999638264 0.0116979199397159 2.18863394527812 9.62212676781521 0.227458440123531 0.820157376199652 -45.8206667937898 17.9170691612028 -2.55737511428536 0.0108313523986738 PERM1 other 1 1 1 0.227458440123531 -2.55737511428536 5.92446873736485e-14 13.2131673743323 5.43091355887283 2.43295482999267 0.0152979570409708 -82.3852811528199 12.9578731968268 -6.35793234749317 4.33970644153272e-10 VMAC other 5.87885032808714e-10 6.1276654954442e-06 1 2.43295482999267 -6.35793234749317 3.33187506118487e-06 24.6950340141661 9.3325849458292 2.6461086780895 0.0083843081815167 -47.5704717839948 19.0489908300879 -2.49726991882726 0.0128176086255084 B3GLCT other 0.0211907253891358 1 1 2.6461086780895 -2.49726991882726 0.102612913622199 -2.33828726895752 36.1273290208635 -0.0647235024656034 0.948417795964608 -169.512881149219 83.9743808877614 -2.01862614951322 0.0440135516035446 SPRY4 other 1 1 1 -0.0647235024656034 -2.01862614951322 0.0935452560249717 -0.404640016979695 16.6127844650717 -0.0243571460179026 0.980576762029197 57.6752699175884 30.0674494497056 1.918196287785 0.0556151040758082 TRPV2 other 1 1 1 -0.0243571460179026 1.918196287785 0.43970862611956 -5.42838428907902 9.28274347128789 -0.584782322798142 0.558939247241393 22.0584149016809 25.6520390488932 0.859908830625014 0.390222312207864 AMTN other 1 1 1 -0.584782322798142 0.859908830625014 0.0345286645747751 25.3772127647408 10.4869651143112 2.41988148984203 0.0158553086895335 41.1805865861893 26.4954570602015 1.55425084732907 0.120711535461055 C2orf88 other 1 1 1 2.41988148984203 1.55425084732907 1.38711973164584e-15 154.436595740862 24.5484360671584 6.29109713214978 6.82892154009046e-10 -198.709021419884 57.1113659609765 -3.47932531600908 0.000546071802598232 TMEM203 other 1.45985788972043e-11 1 7.65044080136334e-06 6.29109713214978 -3.47932531600908 0.00322313064104981 21.8696899004028 6.46622177351953 3.38214349374214 0.000771436231157127 6.77003790042955 21.0995995661173 0.320860966067868 0.748440121111501 KBTBD12 other 1 1 1 3.38214349374214 0.320860966067868 3.51934007723374e-19 713.858885084707 233.523064406529 3.05690954723849 0.00234804353811866 -4038.78519146832 509.983502337776 -7.91944283090422 1.38809206623823e-14 THSD4 other 4.08771349970699e-15 2.07630811267915e-10 1 3.05690954723849 -7.91944283090422 0.92771363884167 2.68031167853748 6.9308109295259 0.386724108591551 0.699112529621784 1.97220094893038 14.1080646412198 0.139792451982972 0.888876003869329 GABRD other 1 1 1 0.386724108591551 0.139792451982972 0.475599575398391 0.309816745883527 7.94566761850508 0.0389919086423875 0.968911718835376 -16.4693990472602 15.2083160026515 -1.08292062345291 0.279342666014889 AMY1C other 1 1 1 0.0389919086423875 -1.08292062345291 4.041790908137e-61 554.348633250579 29.0714939531578 19.0684604700325 4.79392398192388e-61 -251.131830884987 233.206327615632 -1.07686542407588 0.282070278094979 TCEA1 other 6.21950784944122e-57 1 7.4118858684525e-57 19.0684604700325 -1.07686542407588 9.6039426511645e-05 22.3857786488324 6.93528436811284 3.22780977111163 0.0013225573326492 -30.0237693148179 15.5383529978468 -1.9322362749114 0.0538492179462071 NHEJ1 other 0.523222795635442 1 1 3.22780977111163 -1.9322362749114 6.09027928289976e-39 247.837217203616 27.1610702117996 9.12472208462342 1.52101233126287e-18 -176.872406207153 58.6066921326123 -3.0179557960196 0.00266793935829309 FANCA ts 8.87962719446786e-35 1 2.05838598789805e-14 9.12472208462342 -3.0179557960196 4.00176420809363e-26 226.401587389073 37.0542301351661 6.11000651108409 1.90619339404251e-09 -582.57560905032 81.615058391515 -7.13808971692026 3.06117372974604e-12 SECISBP2 other 5.25231552312288e-22 4.47512987551574e-08 2.09719397212556e-05 6.11000651108409 -7.13808971692026 0.43490906224642 23.7172327620341 37.660647275498 0.629761687008086 0.529114435129191 -67.3452567963778 84.3903019972523 -0.798021279726793 0.425205716486518 ADH1A other 1 1 1 0.629761687008086 -0.798021279726793 8.00344658050002e-07 141.485283543795 27.0716030106377 5.22633563620888 2.47138462876255e-07 30.8759076326684 59.7205808888976 0.517006150528057 0.605362769796861 SEMA4D other 0.00539352265059896 1 0.00246940752105954 5.22633563620888 0.517006150528057 0.497722380769485 0.0628024698466489 4.55677847936855 0.0137822082269296 0.989008846209469 9.92325850628694 9.21496838162845 1.07686300107883 0.282024106606304 FAM69C other 1 1 1 0.0137822082269296 1.07686300107883 0.00383174769964224 55.826845803881 26.8221112418862 2.08137403131414 0.0378719543115573 239.278639427438 80.5600289448677 2.97019058410705 0.00310901111528611 DNAH17 other 1 1 1 2.08137403131414 2.97019058410705 1.21663883365015e-16 164.324254231322 23.7688557496458 6.91342721593868 1.33744795729496e-11 -239.862476171659 69.1244542828331 -3.47000896658404 0.00056196067146981 MCRS1 essential 1.32260807606108e-12 1 1.5811309751141e-07 6.91342721593868 -3.47000896658404 2.5268612963313e-10 24.7382716049383 6.40675388249609 3.86128015195431 0.000126868916110997 -59.5578508085547 14.5110847829602 -4.10430038135337 4.70122978764156e-05 FANCM other 2.13949345960371e-06 0.543556188047117 1 3.86128015195431 -4.10430038135337 6.46153758361003e-33 32.1231597742625 4.43504778175066 7.24302450729909 1.49849918339871e-12 -61.3216672521091 10.0238592711281 -6.11757064753841 1.81104999393415e-09 ZNF70 other 9.07975261248882e-29 2.52261153655087e-05 1.81558161060587e-08 7.24302450729909 -6.11757064753841 0.000270109185474399 64.2861326199923 16.7240393462301 3.84393574357881 0.000136096484503595 -1.50564901084987 38.576264511209 -0.0390304512354319 0.968881119178593 CARD9 other 1 1 1 3.84393574357881 -0.0390304512354319 0.0481246442389603 -0.67458031317168 5.89191653096128 -0.114492510141114 0.908889940418089 -129.618833246909 52.4971780854549 -2.4690628710731 0.0138551114423261 PEAR1 other 1 1 1 -0.114492510141114 -2.4690628710731 8.53280158203735e-10 21.0085415212839 3.39696617030561 6.18450124847546 1.22913487121127e-09 -1.6604612066232 7.38196652698644 -0.224934805725956 0.822114926445001 ZFP69B other 7.00798993932728e-06 1 1.36360222612179e-05 6.18450124847546 -0.224934805725956 0.00287106695649669 10.0408270086365 4.3493699712669 2.30857045387466 0.0213435216167462 -15.693496070361 9.26709056849329 -1.69346527417316 0.090942576749177 ZFP69 other 1 1 1 2.30857045387466 -1.69346527417316 0.0934862220434946 1.19182714418978 6.74358005041257 0.176735077700584 0.859782873989961 -22.7253198432573 12.1740963372914 -1.86669459593856 0.0624869772754714 TMEM220 other 1 1 1 0.176735077700584 -1.86669459593856 0.0718221901797376 260.453793162623 163.339669190071 1.5945532059303 0.111398352930817 1316.19314702631 647.090237108205 2.03401793374024 0.0424389289489119 HIST1H1C other 1 1 1 1.5945532059303 2.03401793374024 1.22903788421874e-08 118.412066843297 23.6258127642658 5.01197855179808 7.32629605337681e-07 -47.5231559616679 43.1491376665993 -1.10136977310799 0.271229164291378 PLSCR3 other 9.45375940541058e-05 1 0.0071101703198022 5.01197855179808 -1.10136977310799 1.47293272336075e-24 228.913779283033 21.064865714278 10.8670894174214 1.34849766540222e-24 48.4903993668997 132.564639821638 0.365786829973228 0.714695274733277 EIF4EBP1 other 1.89139291006753e-20 1 1.92632891502707e-20 10.8670894174214 0.365786829973228 0.801604549825398 6.23564723859419 10.2438746378872 0.608719596736524 0.542970136791173 -1.66496777806251 23.8522039186219 -0.0698035193621094 0.944376275831697 P2RX2 other 1 1 1 0.608719596736524 -0.0698035193621094 2.91949398156843e-19 23.533304387206 6.05307179178566 3.88782839469077 0.000113689910728887 -78.1434477227338 13.0395014656788 -5.99282479689998 3.76369481813901e-09 CCDC157 other 3.40091853912907e-15 5.20293171659537e-05 0.934076306548539 3.88782839469077 -5.99282479689998 1.73601524728524e-13 29.5882952032873 15.3725843468885 1.92474437190361 0.0547854005177581 -233.441381357661 35.0630923469272 -6.65775223268689 6.84010110809359e-11 FAM122A other 1.69244126457838e-09 9.80254889800893e-07 1 1.92474437190361 -6.65775223268689 0.00309432202229876 19.7930743850732 6.07405501509734 3.25862612964101 0.00119089879867286 -2.12582325986402 21.2010956230011 -0.100269500108179 0.920168074203861 PALM3 other 1 1 1 3.25862612964101 -0.100269500108179 0.121279390490714 7.80919495237831 7.38269947815096 1.05776958353642 0.290637869484859 53.7416550179862 27.4546762007038 1.95746817864887 0.0508119484898502 DMBT1 other 1 1 1 1.05776958353642 1.95746817864887 0.442163038871424 -0.983716959825268 1.40377312395015 -0.700766343963857 0.483765327515915 -4.0363907983193 3.25539945841068 -1.23990645384266 0.215574652239559 LCN10 other 1 1 1 -0.700766343963857 -1.23990645384266 0.107911673443681 -119.358694112392 139.227848207383 -0.857290374369676 0.391660552336206 -488.649012273397 232.628555826124 -2.10055472570029 0.036138073172846 LDLRAD2 other 1 1 1 -0.857290374369676 -2.10055472570029 1.19582175998311e-24 38.0337521663776 5.71253251492458 6.65794935381296 6.78889273584143e-11 -137.471739184775 20.407340144795 -6.73638691810792 4.1353532065271e-11 PMS2CL other 1.53734845463429e-20 5.94911912290988e-07 7.85542778464212e-07 6.65794935381296 -6.73638691810792 2.37110187121802e-17 293.326065105009 34.7908802592323 8.43111938874182 3.76616112010774e-16 -539.197510931398 237.69562778424 -2.26843680701118 0.0237324626565868 CYHR1 other 2.63050041592927e-13 1 4.9148402617406e-12 8.43111938874182 -2.26843680701118 3.07132646430855e-08 -438.682057675762 79.0128653049569 -5.55203327942394 4.4741159751912e-08 -1983.38148329746 871.990719051956 -2.27454425828503 0.0233327937802519 COL14A1 other 0.000230718043998858 1 0.0004656659906979 -5.55203327942394 -2.27454425828503 0.00225155915771234 44.6271430846217 25.7110695194718 1.73571710234863 0.0831842996719029 180.090721451805 52.5339853787913 3.42808032083 0.000654239189480277 DNER other 1 1 1 1.73571710234863 3.42808032083 5.46071009482118e-32 8.44766567907543 0.691850799487548 12.2102419847351 2.243187735187e-30 -3.63884088797405 2.29258592451143 -1.58722115889703 0.113061204110471 CPSF4L other 7.61059165915228e-28 1 3.30219666496878e-26 12.2102419847351 -1.58722115889703 3.14150267071429e-05 24.6464017036068 7.6412663825542 3.22543417147151 0.00133754547939286 -20.7106675489709 14.2285693754671 -1.45556921447635 0.146119854447433 KLHL17 other 0.181924419661064 1 1 3.22543417147151 -1.45556921447635 0.2585815359509 -33.2907021783468 21.2166419254428 -1.56908441474072 0.117211863397657 -2.12809903173711 46.3020942947693 -0.0459611830555475 0.96335811754598 ANKRD19P other 1 1 1 -1.56908441474072 -0.0459611830555475 5.7037369260584e-10 29.7133749259632 5.85037974678042 5.07887969876059 5.22464040318637e-07 -95.5770413608193 31.1460752978174 -3.06867046479904 0.00225727880352995 RINL other 4.7363831433989e-06 1 0.00511723971874818 5.07887969876059 -3.06867046479904 0.0454000152088545 -134.214087146204 173.075795792408 -0.775464220931186 0.438402983809537 -1747.05581622609 738.088092796044 -2.36700176209028 0.0182826144536524 TPRG1 other 1 1 1 -0.775464220931186 -2.36700176209028 9.17551902237067e-05 42.7109642503929 10.5793149515503 4.03721454990185 6.19005406309427e-05 -26.6475276461909 33.2271316849558 -0.801980980448459 0.42291608587092 MORN2 other 0.501075093811662 1 0.521697756437585 4.03721454990185 -0.801980980448459 0.0197648319442775 2.64732289594329 0.945444187759638 2.80008373864616 0.00529254128920958 -3.74812357639189 9.76136648823859 -0.383975294945434 0.701148463530454 S100A3 other 1 1 1 2.80008373864616 -0.383975294945434 9.90841254551289e-11 29.4845713349698 9.20684913337466 3.20246057123807 0.00144196540992493 -103.488717609307 20.9153214486056 -4.94798599503266 1.00022079217626e-06 RILPL1 other 8.54006077297756e-07 0.0127008036190542 1 3.20246057123807 -4.94798599503266 5.07585442273635e-12 24.3199058684248 4.35202760487833 5.58817821862247 3.66545973899569e-08 -51.5031134713446 16.0190365994253 -3.2151192833402 0.00138291018178396 ZNF490 other 4.66572538537925e-08 1 0.00038293057893288 5.58817821862247 -3.2151192833402 5.1597647285678e-22 129.95392311335 12.5690847876129 10.33917149174 5.32349318190341e-23 96.2846014840038 45.6675285521655 2.10838213795649 0.0354537533344307 NWD1 other 6.36044198090553e-18 1 7.51730472216581e-19 10.33917149174 2.10838213795649 0.0236798847469263 136.140309000327 93.3892562229993 1.45777270862127 0.145476024922976 482.896324843237 180.466601773964 2.67582101118116 0.00767764131735469 ARL4C other 1 1 1 1.45777270862127 2.67582101118116 0.000394649540401958 3.35423366517615 1.40475460159255 2.38777197196827 0.01729304179197 -12.0119252008354 4.9245654573994 -2.43918479807937 0.015040788498045 TMEM221 other 1 1 1 2.38777197196827 -2.43918479807937 0.287943346383552 6.23452130145398 9.20365050887215 0.677396571658606 0.498443407179007 -13.5744349365025 15.0186876824153 -0.903836288732215 0.366483755912441 RAB42 other 1 1 1 0.677396571658606 -0.903836288732215 5.51314841200784e-06 28.7218267072221 40.4282187645426 0.710440073417543 0.477735728120162 -309.24518791281 78.8435177244256 -3.92226522659334 9.89441673092916e-05 WNT7B other 0.0342917831226888 1 1 0.710440073417543 -3.92226522659334 8.51253201788023e-09 27.7358067370957 15.908794542591 1.74342604418213 0.081836902285049 -179.032047588392 38.0485015859723 -4.70536394669475 3.23508330229673e-06 C11orf95 other 6.61253487148937e-05 0.0401182680317818 1 1.74342604418213 -4.70536394669475 0.0101073340762012 1.74849086789104 2.62331471878821 0.666519672751548 0.505369022705292 -11.0697377010539 4.90191997343153 -2.25824529185544 0.0243362009869661 PRSS45 other 1 1 1 0.666519672751548 -2.25824529185544 2.55040566272678e-21 85.1280658766673 8.3450471645658 10.2010287297276 2.85632506888022e-22 46.885258573699 106.704691614261 0.439392662725552 0.660572343707651 GPR89B other 3.09976304247813e-17 1 4.00571027659763e-18 10.2010287297276 0.439392662725552 0.252897651787345 5.01263194785704 3.1301150656492 1.60142098380572 0.109863141581138 -4.25037271737987 19.5310748205896 -0.217621035013349 0.827805844014247 MESP2 other 1 1 1 1.60142098380572 -0.217621035013349 0.616901603666714 3.02611657048553 5.48305456361676 0.551903420871565 0.581243272502786 -6.82846217749168 11.6412948594649 -0.586572392498057 0.557736504120117 FAM25A other 1 1 1 0.551903420871565 -0.586572392498057 0.862197049124321 -1.40611533134274 6.29298466472203 -0.223441722212564 0.823283361468183 -8.92601961429932 16.388934661495 -0.544636963821116 0.586247019536892 EYS other 1 1 1 -0.223441722212564 -0.544636963821116 9.87451076819535e-22 215.899937333153 26.5648457543435 8.12727991457854 2.99353246167014e-15 -519.724180793103 127.12057280836 -4.08843485606859 5.00137880895474e-05 C6orf132 other 1.2103187848577e-17 0.577109100765287 3.84399503403063e-11 8.12727991457854 -4.08843485606859 3.60776565951022e-16 168.40327734378 24.0812605039498 6.99312551833235 8.10017486061303e-12 -92.8677820152117 51.3324460282482 -1.80914390800911 0.0709929832206283 MAPK12 other 3.86680323386305e-12 1 9.63434797921313e-08 6.99312551833235 -1.80914390800911 4.58319777410206e-06 491.785314523531 285.55981188207 1.72217971178181 0.0856338972612366 -1822.75748772194 533.762176475222 -3.41492441401298 0.000688043340595512 AGRN other 0.0287229004502976 1 1 1.72217971178181 -3.41492441401298 0.00114591136206326 51.0118145022772 16.5532962686267 3.08167108680096 0.00217078955213898 -37.5590555466807 38.576478959447 -0.973625809295974 0.330708491898147 FAM166A other 1 1 1 3.08167108680096 -0.973625809295974 9.62233375383183e-07 12.1769363168923 2.45973452831462 4.95050834824674 9.87894042917351e-07 0.0115753399087123 5.01241720026475 0.00230933289194301 0.998158264058821 TMPPE other 0.00643541681456273 1 0.00950749226903658 4.95050834824674 0.00230933289194301 0.000592525289791904 7.78465187750909 19.5163760305531 0.398877940521444 0.690139956181652 -240.579790149514 68.0453305532465 -3.53558118086085 0.000441632371759956 ZNF626 other 1 1 1 0.398877940521444 -3.53558118086085 0.341538152769766 -14.6519146356113 18.6919903037693 -0.783860594698504 0.433464960510176 -84.3396634730251 60.1162218858073 -1.40294351220592 0.161207312629792 HEPACAM2 other 1 1 1 -0.783860594698504 -1.40294351220592 0.0581024256659949 14.5527444087993 7.21836727741458 2.01607148119675 0.0442817566095685 27.1807039728774 13.5280907166796 2.00920473865278 0.0450070860791966 SMTNL2 other 1 1 1 2.01607148119675 2.00920473865278 4.73367230833703e-06 -44.4636832602797 14.9238111591454 -2.97937857737044 0.00301706616561978 -179.889000308706 39.2746303110287 -4.58028500546297 5.75956276225012e-06 ZC3H6 other 0.0296233213055732 0.070531605586515 1 -2.97937857737044 -4.58028500546297 4.34592144279071e-05 105.345084138555 67.9129507020113 1.55117813391422 0.121445937795495 -788.749476026227 216.830900299342 -3.6376248723652 0.000301604445983566 LAMTOR4 essential 0.248239032812205 1 1 1.55117813391422 -3.6376248723652 1.54210979191636e-06 87.430337328728 18.748968203649 4.66320793651525 3.96829245249127e-06 -73.9231544095104 67.6625145015771 -1.09252744971202 0.275110160116868 PRKAR1B other 0.0101177823447632 1 0.0367582929874267 4.66320793651525 -1.09252744971202 7.16429475277058e-12 8.75091124122135 1.59293916666842 5.49356273254527 6.08070951632156e-08 -22.3665481118103 5.93813279024055 -3.76659615099384 0.000183708397265925 NUTM2B other 6.5452996861312e-08 1 0.000628988592368302 5.49356273254527 -3.76659615099384 1.41005955626929e-06 32.8258707859083 7.76095800248062 4.22961582518758 2.74969660706768e-05 -26.013558604545 19.471347926409 -1.33599166852043 0.182114737387082 NCR3LG1 other 0.00928915934752296 1 0.239058623018464 4.22961582518758 -1.33599166852043 4.98044099185627e-17 63.2389004591961 7.61394039533958 8.30567316995337 7.8957727321192e-16 -43.976146639174 40.7154617235311 -1.08008468472699 0.280582207199294 DCUN1D3 other 5.4749987823476e-13 1 1.02455546971979e-11 8.30567316995337 -1.08008468472699 0.00899378663770863 54.0690883593281 17.61026659517 3.07031628778169 0.00224649961092424 52.5648115972537 46.5720491675755 1.12867723316436 0.25953798989081 POTEE other 1 1 1 3.07031628778169 1.12867723316436 8.98240093329906e-25 58.300529836948 5.7305574152328 10.1736228454801 2.37511916924038e-22 -58.4897875848163 27.686998987617 -2.11253619834261 0.035101445294681 ZNF793 other 1.15693324020892e-20 1 3.3337172659458e-18 10.1736228454801 -2.11253619834261 4.19019067374234e-09 1241.9576028497 243.622738297309 5.09787227386821 4.86474817481851e-07 -1104.76171000442 567.74839799014 -1.9458649534113 0.0522253423115308 TUBB4B other 3.31695493733444e-05 1 0.00477572328321933 5.09787227386821 -1.9458649534113 1.46230538489006e-11 19.9876846453066 4.68709043809877 4.26441198634397 2.36267073454826e-05 -57.9117322023947 13.4018859587199 -4.32116288563957 1.84504167558735e-05 AGAP4 other 1.31432007993918e-07 0.219190951059777 0.206521048906864 4.26441198634397 -4.32116288563957 2.947137533161e-18 257.571816398832 46.9233209662187 5.48920688252787 6.30437587001748e-08 -384.921156065717 89.7711253784931 -4.28780584450526 2.14920230396139e-05 COMMD6 other 3.34706409641094e-14 0.254143172443434 0.000651557246166307 5.48920688252787 -4.28780584450526 0.428631435032186 176.638979348734 306.439855814828 0.576422994584201 0.564566411111065 -362.100933369445 515.782643199732 -0.702041718819967 0.482951754139343 PLA2G2A other 1 1 1 0.576422994584201 -0.702041718819967 0.111542931017213 5.19454111401729 4.33798903922481 1.19745372038689 0.231657076284746 -10.0857586389044 9.30765136416377 -1.08359866998634 0.279028158928964 IL17REL other 1 1 1 1.19745372038689 -1.08359866998634 5.70426429437184e-34 48.3233742492269 3.84552556802994 12.5661300111919 5.79603430522352e-32 -8.69510539535363 9.2522108105772 -0.939786778897572 0.347745571821913 HYKK other 8.07552696154222e-30 1 8.57755116830029e-28 12.5661300111919 -0.939786778897572 6.63110837973095e-05 1.91948069642087 0.447135749528033 4.29283656797057 2.08815226233626e-05 3.69462580636115 1.66184303608307 2.22320984963136 0.0266109774491162 OR7A5 other 0.369153803499622 1 0.183277124065253 4.29283656797057 2.22320984963136 0.00158062688305545 4.81438188438827 2.8962484546066 1.66228207277273 0.0970322823666132 -10.4379331246014 5.08265901966549 -2.05363631205942 0.040488371781269 C15orf62 other 1 1 1 1.66228207277273 -2.05363631205942 0.451784554342466 -2.65177665017545 4.44851379466553 -0.596103951246672 0.551353729247738 9.18006656566786 10.0705811533113 0.911572671518502 0.362397474726335 RUFY4 other 1 1 1 -0.596103951246672 0.911572671518502 1.77369095789563e-20 36.5817641135083 4.72840200056545 7.73660194482906 5.01754787556822e-14 -95.6612053485058 21.6851218389642 -4.41137504593681 1.2395126880943e-05 ZNF383 other 2.11973806378107e-16 0.148803498205721 6.29250679075011e-10 7.73660194482906 -4.41137504593681 0.00587898803669973 32.3503128361194 15.806306884187 2.04667118468283 0.0411964909040912 -37.8375011258626 29.4324425837385 -1.28557122020066 0.199169397123636 HES4 other 1 1 1 2.04667118468283 -1.28557122020066 0.276641496339988 7.97492309374374 5.18532765351062 1.53797862481158 0.124635259146106 14.8186495533529 15.299328913417 0.968581670295193 0.333184372741805 IGFL1 other 1 1 1 1.53797862481158 0.968581670295193 8.92936211269804e-14 23.1718694979037 2.96702548827555 7.80979792370146 3.00841586184001e-14 -21.4966630876872 18.738074129371 -1.14721838217046 0.251800345178655 ZNF669 other 8.79720755343011e-10 1 3.79180735226314e-10 7.80979792370146 -1.14721838217046 9.86107602262067e-10 18.2119959658966 34.959332226045 0.520948050384339 0.602615332078718 -458.238648694427 76.3475274295264 -6.00201033514032 3.56552231367229e-09 CENPP other 8.07129072451502e-06 4.93254356873424e-05 1 0.520948050384339 -6.00201033514032 1.25743077936396e-08 330.802949481206 54.2573116425216 6.09692849621311 2.05324373017753e-09 -48.03406645121 199.73057150729 -0.240494312356467 0.810037841536059 PLSCR1 other 9.66335553941203e-05 1 2.25507758885398e-05 6.09692849621311 -0.240494312356467 1.16228636635752e-36 23.0726964907091 6.64826131118057 3.47048580234159 0.000562617634739149 -123.426869125953 12.0344111715356 -10.2561618816788 1.32174479547682e-22 C3orf62 other 1.67380859619146e-32 2.05042270122319e-18 1 3.47048580234159 -10.2561618816788 3.18419910595903e-17 3.08088376718033 1.49292736891068 2.06365281482401 0.0395252615768567 -21.028894795496 2.83879038396329 -7.40769551506554 4.94359680905756e-13 ENO4 other 3.52076895145889e-13 7.28735605623175e-09 1 2.06365281482401 -7.40769551506554 9.68981500545639e-09 36.9473883081981 6.90201049340498 5.35313418365593 1.28663917542996e-07 -45.0052428656641 26.8233065771838 -1.67784097520423 0.0939643702403847 ZNF559 other 7.49700986972161e-05 1 0.00130503811563861 5.35313418365593 -1.67784097520423 2.1183370980031e-07 188.706034694341 33.7084601018847 5.59818022312418 3.45376202206544e-08 146.696155500746 199.473187852111 0.735417912955327 0.462404892320616 SBK1 other 0.00149639332602939 1 0.000361228969887825 5.59818022312418 0.735417912955327 0.000187549511988584 66.3922947864235 28.0934054062248 2.36326973631017 0.0184779239218983 214.743618067062 51.6670174650459 4.15629987181554 3.77643531370011e-05 SLC38A3 other 0.98294699233217 0.438821783451953 1 2.36326973631017 4.15629987181554 6.35417506762858e-27 187.127750797795 20.375145695219 9.18411841549212 8.70272227187728e-19 -55.0147996991692 38.9606678290515 -1.4120599765014 0.158505111656504 GTF2F2 essential 8.42182363463493e-23 1 1.18113346673918e-14 9.18411841549212 -1.4120599765014 1.6018326109119e-16 49.2564433869556 5.64260019856704 8.72938745500069 3.40125567807537e-17 111.843109400408 63.0964011967973 1.7725750958691 0.0768778664871823 FAM92A other 1.73334306826777e-12 1 4.51924841945874e-13 8.72938745500069 1.7725750958691 4.43906577694918e-12 123.847705302653 31.5484175948423 3.92563921567022 9.77781231128616e-05 -313.344075089554 72.6789934898499 -4.31134307237365 1.93151541132294e-05 FOCAD other 4.08882348714789e-08 0.229058412628787 0.808918412512704 3.92563921567022 -4.31134307237365 1.37401047004366e-09 54.9835583107008 12.3542585444166 4.45057533101007 1.04378430491163e-05 -119.928013973164 39.4784125237084 -3.03781247285824 0.00249999550583373 PRR19 other 1.1172079131925e-05 1 0.0939301495989972 4.45057533101007 -3.03781247285824 1.68966233177296e-12 71.6032973469417 12.2379631029969 5.85091626313266 8.49036086181927e-09 -139.032966677709 41.7781111272787 -3.32789020198015 0.000934792769550257 ZP3 other 1.58321360487127e-08 1 9.11270431299062e-05 5.85091626313266 -3.32789020198015 0.948589335303075 -10.0040436500667 34.3391488964997 -0.29133056501253 0.770915358849658 16.0067720915897 169.584719815519 0.0943880563591017 0.924837472515847 H3F3C other 1 1 1 -0.29133056501253 0.0943880563591017 0.000702581828848915 -0.670055591755692 4.77153289746776 -0.140427742227511 0.888375291579161 -34.6627159537186 9.67192549716501 -3.58384852777028 0.000369751048065911 JAKMIP3 other 1 1 1 -0.140427742227511 -3.58384852777028 0.297866377904547 1.31819497653443 3.59727278254879 0.366442873870812 0.7141771071804 10.7746609894088 6.96799495673114 1.54630723132203 0.12261190341897 PDCD1 other 1 1 1 0.366442873870812 1.54630723132203 0.154443461038893 -19.7024115368948 12.4561445808573 -1.58174236088859 0.114288526349209 93.7120320903188 94.256916427194 0.994219158046656 0.320557390325904 SELL other 1 1 1 -1.58174236088859 0.994219158046656 7.19207443474108e-30 71.8150097285258 7.11925625818439 10.0874314849906 4.80235151216682e-22 -83.9786855777847 22.4029668375895 -3.74855197468214 0.000196965028624785 BLOC1S5 other 9.83012733740411e-26 1 6.72185141157989e-18 10.0874314849906 -3.74855197468214 0.423836820210935 -16.3734481062373 13.2278641842102 -1.23779983512244 0.21632720410132 -27.056859352822 35.871399367142 -0.754273873619938 0.451012967246577 CERKL other 1 1 1 -1.23779983512244 -0.754273873619938 5.07818598248374e-14 28.4686155716491 7.86114401279111 3.62143417361735 0.00032085579884076 -66.7653610687139 13.948405352427 -4.78659455197843 2.19814216468655e-06 SLC24A5 other 5.05076377817832e-10 0.0274789752007466 1 3.62143417361735 -4.78659455197843 0.00882832897079017 34.771746613799 40.4954742339417 0.858657597461957 0.39090832402965 -223.045817230202 89.6511721207391 -2.48792973871899 0.0131477410746562 IER5L other 1 1 1 0.858657597461957 -2.48792973871899 1.23259259286596e-09 270.395856375033 51.628674081525 5.23731940022438 2.34768195277911e-07 -19.2136604122611 95.5681962272456 -0.201046594691126 0.840738693510441 H2AFX essential 1.00382340763004e-05 1 0.00234815148916967 5.23731940022438 -0.201046594691126 8.06228369396776e-05 447.711135664696 211.666773880256 2.1151696482981 0.0348669863522928 -1171.37382013885 438.224943102237 -2.67299668486823 0.00774213796424098 SERPINA5 other 0.443909340189865 1 1 2.1151696482981 -2.67299668486823 1.26103872176563e-11 28.585445609595 8.7643797909944 3.26154802636089 0.00117708650982707 -175.290647981555 33.4046762438378 -5.2474883067873 2.20898888935187e-07 C19orf54 other 1.13682640767171e-07 0.00287831252282549 1 3.26154802636089 -5.2474883067873 5.41459958536427e-15 22.4572829245623 2.95133705999923 7.60918948531353 1.23914547228677e-13 36.6557078682867 6.79398605335999 5.39531691416388 1.02593189745675e-07 LCTL other 5.58678385217885e-11 0.00135761567990452 1.53988607841077e-09 7.60918948531353 5.39531691416388 4.95186461993038e-15 397.755021078564 47.5388635031345 8.36694425924459 5.00588417419173e-16 518.474034964258 254.365261356804 2.03830520016246 0.0420025077452084 NCCRP1 other 5.11676171177406e-11 1 6.51716060638021e-12 8.36694425924459 2.03830520016246 2.39830216516711e-09 15.0767940156974 2.36992876396585 6.36170767870164 4.2193153667316e-10 3.91747520712854 12.8660006061381 0.304482746974192 0.760875938597272 KRTDAP other 1.92631629906222e-05 1 4.76824829594338e-06 6.36170767870164 0.304482746974192 0.836497606355333 -0.696111515554556 1.50246480614114 -0.463313025842127 0.64332772610306 0.47723527870072 3.1594684026834 0.151049232932791 0.879993602820025 C22orf34 other 1 1 1 -0.463313025842127 0.151049232932791 0.419237929724896 3.10923365866238 2.85725051048184 1.08819077895205 0.276994535340851 6.98724417273507 6.19358122787334 1.12814281683914 0.259758735039881 COL25A1 other 1 1 1 1.08819077895205 1.12814281683914 6.12660653005009e-44 230.637174693338 17.1154044808469 13.475414790894 8.1143382586791e-36 -64.8429353955489 43.9595341635267 -1.47505965723698 0.140788052291142 FAM83G other 9.11577785606153e-40 1 1.21487872408944e-31 13.475414790894 -1.47505965723698 1.2507334970916e-05 246.883865486021 58.8342320937063 4.19626222184399 3.1653304899061e-05 12.6941443662603 99.3820104926048 0.127730806645383 0.898408867231825 SRSF10 essential 0.0753942152046816 1 0.274022660511171 4.19626222184399 0.127730806645383 0.135928383044743 110.484863238545 85.0931252730751 1.29839940516915 0.194721264794064 711.361628317946 378.607269418826 1.87889057019404 0.0608142830084959 HBA2 other 1 1 1 1.29839940516915 1.87889057019404 7.95093547165239e-17 7.80654760117961 3.70544228074699 2.10677889701357 0.0355923414117605 -53.0583407878889 7.21040848339833 -7.3585762734599 6.86684165176377e-13 DUSP28 other 8.69037247051606e-13 1.01038708064052e-08 1 2.10677889701357 -7.3585762734599 0.00026327079982987 127.500184452202 32.0414659260617 3.97922444455005 7.85273590842469e-05 155.480603388082 56.6828394780446 2.74299249684387 0.00628930100684395 C15orf52 other 1 1 0.655153756839872 3.97922444455005 2.74299249684387 1.3016113597638e-55 750.227410533831 97.7793210071818 7.67265923720955 8.02871748551248e-14 -2536.65650639623 215.334029890287 -11.7801004685077 1.21684702518876e-28 NBR1 other 1.98677957954346e-51 1.90217526977508e-24 1.00206422936681e-09 7.67265923720955 -11.7801004685077 0.0001668331408208 112.184977174397 52.9403769403372 2.11908157172413 0.0345376978022474 -685.933666476194 230.253296271445 -2.97903950815778 0.00302107375092237 RALGAPA2 other 0.880211650970539 1 1 2.11908157172413 -2.97903950815778 1.0713603999824e-17 46.2772394716251 8.65053876120248 5.34963668149523 1.33749048679377e-07 -107.968833805911 20.125277374048 -5.36483705537095 1.23518211971908e-07 NDOR1 essential 1.19949510382029e-13 0.00162797003378975 0.00135541285931681 5.34963668149523 -5.36483705537095 0.0091177377804798 1.30937967680642 1.53257285098944 0.854367005105872 0.393278439510392 -10.9888497636315 4.163275653293 -2.63947205968448 0.0085421456943618 CFAP54 other 1 1 1 0.854367005105872 -2.63947205968448 1.39801355528545e-16 359.067595462905 48.6966918900211 7.37355211466603 6.40500327551578e-13 -864.609783829987 290.714180773302 -2.97408878208183 0.00307192729823652 CLN3 other 1.51670490612919e-12 1 7.81730649776701e-09 7.37355211466603 -2.97408878208183 0.000170962892888305 21.9496736843358 5.71683059329763 3.83948296632568 0.000147030173079306 55.4501544344039 22.7675068552678 2.43549523392695 0.0153847843263282 FAM72B essential 0.900290593949816 1 1 3.83948296632568 2.43549523392695 7.32412704885319e-08 10.9050513173166 3.13449791647359 3.47904245206363 0.000544459763606473 -30.4221611406277 8.8858873449304 -3.42364920459904 0.000665488382699763 ASAH2 other 0.000534880998377748 1 1 3.47904245206363 -3.42364920459904 4.13098488820517e-41 820.953329127782 55.2187115352589 14.8673032438212 4.23720490254861e-42 385.289000615119 184.797721633777 2.08492289411806 0.0375498463946591 SUMO2 other 6.07750496752744e-37 1 6.42868727814675e-38 14.8673032438212 2.08492289411806 0.00306381660737706 115.866252935078 34.6287643543686 3.34595400948693 0.000876919543213906 40.0026201816083 64.2930606007115 0.622191878996745 0.534077836795994 NANOS1 other 1 1 1 3.34595400948693 0.622191878996745 3.91127752464482e-24 174.305748108697 42.487667652774 4.10250215505339 4.71049950441744e-05 -577.259890338604 84.6563169778763 -6.81886374160906 2.43899595340668e-11 RTL6 other 4.98883448268447e-20 3.52117845793322e-07 0.401099032801145 4.10250215505339 -6.81886374160906 0.0117353660707031 -16.5672515157334 33.0515671077936 -0.501254644347163 0.616395814662969 -184.315290393185 63.5798622680044 -2.89895705681544 0.00389602038996206 DPYD other 1 1 1 -0.501254644347163 -2.89895705681544 0.000214658382019324 663.182336438151 160.493520712612 4.13214398620914 4.16604436131956e-05 247.876803555468 1650.84477561064 0.150151490447537 0.880701267035612 S100A16 other 1 1 0.356446755554501 4.13214398620914 0.150151490447537 2.25686970908893e-05 168.688844551853 42.3885205895138 3.97958792158421 7.84652784070482e-05 -96.1381042656736 94.7801079657763 -1.01432786192212 0.310880588367079 PTAR1 other 0.132455683226429 1 0.654714283028411 3.97958792158421 -1.01432786192212 0.0125840808771246 0.267537632004802 0.602019397975169 0.444400351391729 0.656929248371225 -2.92550926904378 1.16722121433316 -2.50638802064196 0.0124867891313497 CC2D2B other 1 1 1 0.444400351391729 -2.50638802064196 9.93181043313095e-07 6.94833376338659 4.81633521682553 1.44265991684156 0.149700391730809 -45.8408081975431 10.2588823938566 -4.46840176518588 9.61971681763059e-06 SAXO2 other 0.00662749710202828 0.116254277741066 1 1.44265991684156 -4.46840176518588 7.92392246541324e-08 13.1730909886966 3.9016031224984 3.37632777478946 0.000786985833922414 -14.0218521525087 6.19641009554416 -2.26289931368356 0.0240345688790101 RHCE other 0.000577020033931392 1 1 3.37632777478946 -2.26289931368356 4.24889250481835e-12 190.086088965158 28.1235859428291 6.75895632056218 3.57078671634527e-11 35.2731908721126 55.941030675476 0.630542384475157 0.528603117442106 PARVB other 3.91620422169107e-08 1 4.1667510193033e-07 6.75895632056218 0.630542384475157 6.94328693725917e-09 80.9008097794988 13.6413284736086 5.93056680190751 5.38170765344071e-09 -48.3300350112608 46.6920860191612 -1.03507979899265 0.301093242022953 SLC4A5 other 5.42965038493667e-05 1 5.82193133949216e-05 5.93056680190751 -1.03507979899265 9.75473656675496e-21 137.970304625165 24.9157576481304 5.53747177082201 4.80858331614408e-08 -269.186261428713 47.8760685353882 -5.62256404219451 3.02843050851254e-08 UROS other 1.17242178795828e-16 0.000407626746445788 0.000499900321546339 5.53747177082201 -5.62256404219451 6.91608414481206e-05 42.0284213980017 13.4265438381711 3.13024870022891 0.00184015086492233 -78.5773502633224 41.4862220273546 -1.89405895315103 0.0587464092124817 ZBED6CL other 0.384050152561413 1 1 3.13024870022891 -1.89405895315103 1.91937284701166e-32 110.989615470025 31.4008053419925 3.53461047451539 0.000443353043584147 -708.5189726568 71.6699190184277 -9.88586260959253 2.69116155652454e-21 SMIM15 other 2.68558648753872e-28 4.16053576638694e-17 1 3.53461047451539 -9.88586260959253 1.35595539939296e-20 35.4306156163603 3.97097770380867 8.92239097247456 7.11838299341501e-18 -57.2441580472767 21.6330643233855 -2.64614190535159 0.00837943094404501 FAM221A other 1.62402778185294e-16 1 9.55785284525834e-14 8.92239097247456 -2.64614190535159 2.10994193408896e-10 139.273422873009 25.1058984593658 5.54743830811011 4.5381952306174e-08 -110.639924675666 54.6171823705727 -2.02573475733304 0.0432813939201178 TMEM120B other 1.79577158010311e-06 1 0.000472244595698046 5.54743830811011 -2.02573475733304 0.186640946792239 -2.36206071029543 8.72796630840442 -0.270631281885326 0.786779595759117 -41.0627419932076 22.4980826885987 -1.82516628468153 0.0685364966886448 FSIP2 other 1 1 1 -0.270631281885326 -1.82516628468153 1.32245906871559e-31 218.109081671986 17.1061356544654 12.750342104007 9.47800325889173e-33 76.1087908778933 109.912462864524 0.692449144476944 0.488951870407024 RBM34 other 1.83649890872534e-27 1 1.40672524368471e-28 12.750342104007 0.692449144476944 0.000191319768725714 8.29156679077959 20.5547790149083 0.403388758632032 0.686833672089228 -182.440623632279 47.9355240789582 -3.80595867339987 0.000158662607636579 NOXA1 other 1 1 1 0.403388758632032 -3.80595867339987 0.00898480186409392 26.9901105519998 8.94198107287822 3.01835916806657 0.00266145438153251 2.011715120274 19.6316245473589 0.102473186333662 0.918419135959821 TMEM198 other 1 1 1 3.01835916806657 0.102473186333662 0.642527752509155 4.93630384538896 7.22861418572718 0.682883844476806 0.494978621968982 -13.4633450151222 27.24183520408 -0.494215786648096 0.621358560675314 FZD9 other 1 1 1 0.682883844476806 -0.494215786648096 2.2416706461731e-06 9.3996866022915 2.1756304351305 4.32044268664025 1.85144830037785e-05 -25.7685986253355 13.1085610454136 -1.96578392823302 0.0498317677500801 SPRED3 other 0.0145036090807399 1 0.163149624229296 4.32044268664025 -1.96578392823302 0.616705214616831 2.10529543632765 75.5008557622592 0.0278843917075179 0.977764640032418 626.666898822482 638.297238391659 0.981779116578223 0.326647521778973 PRELP other 1 1 1 0.0278843917075179 0.981779116578223 6.83079508335008e-47 128.75126179905 8.19425725997258 15.7123773045272 3.47861504935943e-46 -42.7039102414502 41.1197426350896 -1.03852571793601 0.29948421029055 ZNF548 other 1.02468757045335e-42 1 5.30836656532248e-42 15.7123773045272 -1.03852571793601 2.64595245952786e-10 104.665925154256 22.8536127305619 4.57984155014088 5.77804675540168e-06 -157.48494361181 47.8450141388508 -3.29156436561548 0.00106118107779089 MTF1 other 2.23556523305509e-06 1 0.0529904667937888 4.57984155014088 -3.29156436561548 0.0588275471857677 -17.4381896531487 7.32639873743881 -2.38018571990047 0.0176519223899446 -16.0116164037467 13.1532993656553 -1.21730798932128 0.224021724739583 SHISA6 other 1 1 1 -2.38018571990047 -1.21730798932128 2.25707543628284e-07 119.048509623358 22.8223077722365 5.21632215337053 2.60693597509793e-07 28.0774091727264 37.4571185459641 0.749588069308434 0.453829870373536 TMEM201 other 0.00159010964486126 1 0.00260094002235521 5.21632215337053 0.749588069308434 1.5118816635423e-29 51.2148753027313 20.643994695645 2.48086070829768 0.0134094346714186 -354.808364980322 39.6143693346029 -8.95655720234827 5.38732497687745e-18 NHLRC3 other 2.05888044941191e-25 8.23721988964562e-14 1 2.48086070829768 -8.95655720234827 0.00130621600124115 18.8920884496172 7.40756196748062 2.55037872549078 0.011044481397048 -75.8298400966252 33.9254516010729 -2.23519029277202 0.0258262238289324 ZDHHC11 other 1 1 1 2.55037872549078 -2.23519029277202 0.301868246257955 -2.26035840555172 1.47663907602198 -1.53074535426833 0.126411488884495 -1.42207373624287 2.35944563511755 -0.602715195076752 0.546948414149255 CNR2 other 1 1 1 -1.53074535426833 -0.602715195076752 2.4492290539773e-41 16.7095244264191 2.55533881341574 6.53906415019907 1.44540926749269e-10 -54.9333016381009 5.69178160753648 -9.65133686179452 1.98503602531642e-20 LINC00910 other 3.60648978198158e-37 3.06052854383286e-16 1.65672810240013e-06 6.53906415019907 -9.65133686179452 3.83533830246245e-21 64.3892879915454 7.87095964836313 8.18061467319758 2.02069344188445e-15 -111.508985370031 36.578813937873 -3.04845820204622 0.00241243909590762 SLX4 other 4.64843002258449e-17 1 2.60305729183555e-11 8.18061467319758 -3.04845820204622 0.0160837567200328 -14.9236400291541 13.5844241680111 -1.09858466171106 0.272475881749498 -91.2463276931646 31.6831605373101 -2.87996292496491 0.00414715365401064 ENTPD8 other 1 1 1 -1.09858466171106 -2.87996292496491 3.8251014943222e-13 310.42520686544 312.274560966655 0.994077794568052 0.320626139202667 -3908.4926557192 602.913921087293 -6.48267110613508 2.02062891058812e-10 RPL14 essential 3.67286245484818e-09 2.87293018507419e-06 1 0.994077794568052 -6.48267110613508 0.191099030303203 9.75106803708631 5.3518586948006 1.82199654235258 0.0690105684563567 2.01510439670231 44.5574744767992 0.0452248342250987 0.963944880605544 FAM78B other 1 1 1 1.82199654235258 0.0452248342250987 0.0016321538077762 10.9185387722707 3.79249588113308 2.87898500472692 0.00415197697646723 -18.6899745483147 13.6522233816166 -1.36900591397308 0.171581724601181 ZNF563 other 1 1 1 2.87898500472692 -1.36900591397308 0.0265415444053708 -23.9881220306646 15.7670326758113 -1.52141005374242 0.128741210006668 -84.7245988063037 32.9409694771557 -2.57201291130972 0.0103766496939089 TMC3 other 1 1 1 -1.52141005374242 -2.57201291130972 1.28499455321389e-25 79.3031398697976 8.46160829276845 9.37211191134581 1.90893775700062e-19 -128.454550279633 29.8127588626686 -4.30871060512563 1.95018806339618e-05 FBF1 other 1.67473340120367e-21 0.231233798676885 2.61028148892264e-15 9.37211191134581 -4.30871060512563 1.11926007821852e-05 65.2041822075358 13.9559093729587 4.67215574886698 3.75964127481793e-06 17.4384978656417 41.9444639318462 0.415752073836889 0.677755080273538 KLRG2 other 0.0677823903369135 1 0.0348932306715852 4.67215574886698 0.415752073836889 5.98830825561049e-132 966.048012993221 29.211736600323 33.0705437410571 1.79876982324945e-129 -568.659277148653 296.243140891598 -1.91956943015514 0.0554644878416678 MSL1 other 9.37469657415822e-128 1 2.81579428131469e-125 33.0705437410571 -1.91956943015514 0.393962820885001 -14.8662753370248 28.4431247835174 -0.522666741090264 0.601428366779584 -125.22399650138 93.2428167025266 -1.3429881349561 0.179860565072053 LRRK2 other 1 1 1 -0.522666741090264 -1.3429881349561 0.0283444234387541 57.4883813326912 22.2548023722446 2.58318992777885 0.0100509377559627 17.4862645742593 40.0779413786842 0.436306456188379 0.662788780644282 GJB3 other 1 1 1 2.58318992777885 0.436306456188379 0.0289106731244151 -128.879041396601 91.7686678879679 -1.4043904565983 0.160775392580719 -528.223819398705 201.733853153607 -2.61841932398177 0.00908091994477905 FAM196A other 1 1 1 -1.4043904565983 -2.61841932398177 0.019167402597466 21.478034797097 34.0737664447946 0.630339320776149 0.528741239352307 -180.746752478942 78.4967119878863 -2.30260284668783 0.0216833866802117 HACD4 other 1 1 1 0.630339320776149 -2.30260284668783 8.02012909732819e-13 21.2667282995835 2.77866077321037 7.65358927747508 9.03262797386182e-14 -14.0878920949858 30.8822522543146 -0.456180850378799 0.648443003657955 CFAP126 other 7.59987433262819e-09 1 1.12580662064231e-09 7.65358927747508 -0.456180850378799 7.68883240756401e-05 0.505195422854761 9.30691978596177 0.0542816994744899 0.956730955522162 -123.928655849703 29.7969530800427 -4.15910497683427 3.7201935757338e-05 USP32P1 other 0.424346660573458 0.432584108986326 1 0.0542816994744899 -4.15910497683427 4.11028004893252e-17 101.801273925036 56.6959880142956 1.79556398063593 0.0731207978665007 -948.971841258028 122.745314804113 -7.73122658712047 5.21211945412301e-14 FAM120AOS other 4.5315837539481e-13 7.7582398074621e-10 1 1.79556398063593 -7.73122658712047 1.86695670488423e-13 35.6935823371824 46.0337079758363 0.775379258084497 0.438450051058099 -695.860791462595 97.7739790662702 -7.11703459456168 3.47152900762231e-12 C9orf152 other 1.81766904787528e-09 5.07016811563239e-08 1 0.775379258084497 -7.11703459456168 1.92096844928991e-17 548.537990651204 80.3749665243569 6.8247367852399 2.47878286337567e-11 -340.65176670333 149.663776917091 -2.27611365769581 0.0232481085160885 NOC2L essential 2.13534852823066e-13 1 2.907860177026e-07 6.8247367852399 -2.27611365769581 1.39880690287966e-14 298.182856913518 48.4209810314056 6.15813332489315 1.50518515265346e-09 -366.459252206878 112.538386559584 -3.25630447894199 0.00120469503807414 NELFB essential 1.42048840987429e-10 1 1.66202544555995e-05 6.15813332489315 -3.25630447894199 1.2736967409902e-22 258.900043771156 43.2228602755877 5.9898868820901 3.83618155037523e-09 -367.8557333627 94.8153123770332 -3.87970807816275 0.000117495631636143 ZNF292 other 1.5866440302515e-18 1 4.16954572710283e-05 5.9898868820901 -3.87970807816275 6.23673240780506e-100 198.798300052987 7.67074433682193 25.916428878837 8.18024688020392e-95 -52.2972083305253 37.9259231848124 -1.37893039744034 0.168526649400865 KCTD21 other 9.7386576547876e-96 1 1.27742735281264e-90 25.916428878837 -1.37893039744034 1.20420227254129e-13 182.959171511084 23.0780451836359 7.92784527698283 1.26400126350421e-14 165.222196055853 125.201146528184 1.31965401785406 0.187503613259971 SBSN other 1.18156326981751e-09 1 1.60540800477669e-10 7.92784527698283 1.31965401785406 1.3569310527813e-10 23.949969418366 4.73072555306232 5.06264190338891 5.70734234136809e-07 -16.9795788021341 10.3178678797846 -1.64564801565269 0.100426880745583 ADAT2 other 1.16261852602302e-06 1 0.00557093685940939 5.06264190338891 -1.64564801565269 1.13191409903331e-21 49.737969153224 5.06063812979054 9.8283986875945 4.37098661196447e-21 -10.9202803909527 22.2660386638549 -0.490445586474253 0.624017476387388 ZNF567 other 1.38523647439697e-17 1 6.07042620669626e-17 9.8283986875945 -0.490445586474253 3.89808225033163e-06 324.734837702538 92.1806804392571 3.52280799138301 0.00046296697295612 -882.976078161166 334.446812990966 -2.64010911111602 0.00852631194799684 NDUFA4 other 0.0246124913285939 1 1 3.52280799138301 -2.64010911111602 1.27689354747976e-06 42.9865967013946 12.5539649861326 3.42414502102552 0.000663054618454796 -80.6601109991305 28.9803527557573 -2.78326877795186 0.00556781938790979 ALKBH2 other 0.00844282013593618 1 1 3.42414502102552 -2.78326877795186 5.31166786385769e-36 89.9279258478264 6.67241808926084 13.4775616043251 1.58345696877722e-35 -11.4471071526328 26.6484828040054 -0.429559432588493 0.667701569581226 RNFT1 other 7.62861738607241e-32 1 2.36916831668448e-31 13.4775616043251 -0.429559432588493 0.296936436449617 -28.7864066613183 24.4059360259486 -1.17948382027685 0.238723037808131 -98.2503961884434 73.9256867064069 -1.32904272609115 0.18439306698722 RELN other 1 1 1 -1.17948382027685 -1.32904272609115 5.63871195559022e-07 166.913379133737 40.8006104788492 4.09095298268303 4.95538812186702e-05 -144.874132375641 101.253535866119 -1.43080566161363 0.15306756347589 FAM111B other 0.00384560155371253 1 0.420858065699358 4.09095298268303 -1.43080566161363 0.118774385570714 3982.10481952277 2099.07638710514 1.89707475344169 0.0583445041120678 -8549.68548659679 9852.86498780059 -0.867735983105691 0.38591939663605 APOD other 1 1 1 1.89707475344169 -0.867735983105691 1.05635892342835e-15 1206.6044371625 354.511432341762 3.40356989108124 0.000714110337951907 -3912.49118020616 729.448929493129 -5.36362591268017 1.20817971433104e-07 H1F0 other 1.11636011027908e-11 0.00159358904320264 1 3.40356989108124 -5.36362591268017 1.64656775197215e-20 934.817681630207 100.368836537676 9.31382403022376 3.10064431402338e-19 -321.818820686789 522.340124663356 -0.616109706092746 0.538081730389068 LITAF other 1.96945968813388e-16 1 4.22803858660229e-15 9.31382403022376 -0.616109706092746 1.15427944076587e-11 112.939995264465 24.1572950453264 4.67519211288164 3.72552937161604e-06 -367.421462042471 84.5287021354493 -4.34670653589017 1.65563199154658e-05 TMEM120A other 1.04277604678789e-07 0.197423057276427 0.0345878146860834 4.67519211288164 -4.34670653589017 2.16066100396092e-09 94.9799666749453 37.3084732392267 2.54580148766533 0.0111847176615191 -572.70881787042 112.037665497713 -5.11175251042795 4.46449137941944e-07 ARID2 other 1.73998030648973e-05 0.00575606873548549 1 2.54580148766533 -5.11175251042795 3.46018521257013e-53 1430.64596645203 136.010719962317 10.5186265233241 1.14938712360407e-23 -1473.19562081179 296.94590024547 -4.96115831063493 9.40393956146163e-07 SF3B3 essential 5.26294170831917e-49 0.0119599303342669 1.63201477680542e-19 10.5186265233241 -4.96115831063493 5.48536913844264e-14 61.768284293738 10.0453436410249 6.14894686543906 1.50750774733474e-09 -82.7194741335927 29.5625926435408 -2.79811297780969 0.00532174672621948 BLOC1S3 other 5.44916570212892e-10 1 1.66443930383229e-05 6.14894686543906 -2.79811297780969 0.00382574859967057 40.7508321072195 19.5751684151463 2.08176150738446 0.0378426125296862 169.553362741136 54.0715968469459 3.13571953905987 0.0018092470107044 SP6 other 1 1 1 2.08176150738446 3.13571953905987 0.484362968169605 -12.7777554518832 12.9816490822166 -0.984293703439216 0.325409490163804 -41.3416236890624 47.7551756280462 -0.86569933301183 0.387037386671026 PLAC9 other 1 1 1 -0.984293703439216 -0.86569933301183 3.39807528616482e-05 5.70864928905768 1.27701285392201 4.47031466560814 9.53715016871397e-06 0.628496734423653 3.33001896214328 0.188736683354841 0.85037063777594 UBE2Q2P1 other 0.196000982505987 1 0.0860727802726436 4.47031466560814 0.188736683354841 3.37655937962556e-06 1184.96240825298 293.073234472414 4.04322970804938 6.05300649095221e-05 -2292.14128223412 1100.44162071559 -2.08292856166563 0.0377356334049791 CLDN4 other 0.0214647879762797 1 0.510328977252181 4.04322970804938 -2.08292856166563 2.91949072432473e-17 15.9352911763605 1.87027074130541 8.5203125004447 1.586895709248e-16 -11.4977380160113 9.73077449538197 -1.18158508569568 0.237889504073081 ZNF573 other 3.2321681808999e-13 1 2.08454620366818e-12 8.5203125004447 -1.18158508569568 0.000469643418554124 -0.331524096747952 0.428496380753922 -0.773691708118161 0.439455494457651 -4.6994810989861 1.22127274667519 -3.84801929935801 0.000133477344902075 GRAPL other 1 1 1 -0.773691708118161 -3.84801929935801 8.08701712236651e-19 -11.127683862743 7.44331338080147 -1.4949906437427 0.135501018456968 -199.152067109658 21.3818777146603 -9.31405883839242 3.0947417950857e-19 FAM47E other 9.30653930441938e-15 4.75166655217459e-15 1 -1.4949906437427 -9.31405883839242 1.38124679835056e-34 1288.94118654365 95.8879953410356 13.4421538583573 1.0704367595126e-35 1117.60768468648 320.903595509267 3.48268981814574 0.000537025609913002 JPT1 other 1.96468544597384e-30 1 1.60222974163846e-31 13.4421538583573 3.48268981814574 1.11970705795181e-21 22.9874655740755 2.72791474442887 8.42675366633874 3.26237120097724e-16 -46.67606771601 12.423737439569 -3.75700693475289 0.000190737693099201 ZNF527 other 1.37074538034461e-17 1 4.26163549983656e-12 8.42675366633874 -3.75700693475289 4.57502098739364e-09 672.060193440743 107.356384416801 6.26008594730174 7.85962887129658e-10 -1085.21406401632 1064.70316001897 -1.01926443422689 0.308534717145274 S100A13 other 3.61472408213972e-05 1 8.78470718944819e-06 6.26008594730174 -1.01926443422689 1.80748163596694e-06 -27.6843647912209 42.6656304731466 -0.648868058064799 0.516721574458834 -870.960918638444 167.93609622271 -5.18626393151006 3.12199156048223e-07 ZNF33A other 0.011798234277951 0.00404672546069707 1 -0.648868058064799 -5.18626393151006 0.898732884312784 12.3776882179465 29.0602008421286 0.425932645310646 0.670324469714661 -5.64789274197483 88.4944431314069 -0.0638220044346534 0.949135272448648 KRT77 other 1 1 1 0.425932645310646 -0.0638220044346534 0.463999197619918 -31.658856209424 41.784931863761 -0.75766202784887 0.448983831671874 57.3415532081293 90.9097171112091 0.630752740523698 0.528469061534032 PCDH18 other 1 1 1 -0.75766202784887 0.630752740523698 1.21724504528629e-20 41.7800544111702 4.36521930469227 9.57112380728726 3.70017036568217e-20 -26.2227635219764 19.1461420081943 -1.36961083390865 0.171374537191813 ZNF600 other 1.45947680929826e-16 1 5.09772471280033e-16 9.57112380728726 -1.36961083390865 0.839187019758843 20.4807471638557 34.6664383716963 0.590794674210819 0.554903369793543 8.46699521870489 92.5507847631409 0.0914848560211986 0.927141015813448 PAX8-AS1 other 1 1 1 0.590794674210819 0.0914848560211986 1.05382640850753e-21 52.4227223390304 5.6764932282184 9.23505414900029 5.80347289609934e-19 -20.7120082113405 12.2800847256224 -1.68663398291747 0.0922491923072627 C15orf61 other 1.29114811570343e-17 1 7.89040174953666e-15 9.23505414900029 -1.68663398291747 0.953306238419238 -0.0576710213860539 1.61736125430892 -0.0356574767896835 0.971568630083331 0.726583743027921 3.336774958869 0.217750298412152 0.827705774621073 NUGGC other 1 1 1 -0.0356574767896835 0.217750298412152 1.4642420822299e-29 507.070380238321 56.7023850936311 8.94266404139808 6.15436536611573e-18 -762.84566506425 177.533251703223 -4.29691710001163 2.05704740810647e-05 TSPYL1 other 1.99444414020535e-25 0.24363669501613 8.2690053059131e-14 8.94266404139808 -4.29691710001163 3.11039470192276e-19 134.450860829719 78.3731149486861 1.71552273911467 0.0868146792280857 -961.123788903579 132.3868342458 -7.25996504394899 1.3340442825976e-12 PNRC2 other 3.61956631462751e-15 1.95744317585546e-08 1 1.71552273911467 -7.25996504394899 0.000874344690923865 45.9970674454134 13.4327860191304 3.42423882729215 0.000663356866793547 -1.12933498056383 24.2990482449722 -0.0464765108978087 0.962947637962578 GJB5 other 1 1 1 3.42423882729215 -0.0464765108978087 6.7107070526479e-10 5.4272700322141 11.6993194452115 0.463896217009056 0.642910088148759 -125.730837837937 22.3459129409171 -5.62656975216772 2.96279806973418e-08 FHIT other 5.5423729547819e-06 0.000399088899993194 1 0.463896217009056 -5.62656975216772 0.00321346629946062 45.7274514548241 13.4252095972852 3.40608845794639 0.000707600946413325 29.717577993599 41.6231878057483 0.713966891058135 0.475553301380037 ALKAL2 other 1 1 1 3.40608845794639 0.713966891058135 4.75832391722325e-18 25.4706319283788 4.25126659274919 5.99130432606144 3.79282149327542e-09 -72.4194706342465 14.8910010440008 -4.8633043823083 1.51419494673581e-06 ZKSCAN3 other 5.37500269689538e-14 0.0190667427692973 4.12431409178769e-05 5.99130432606144 -4.8633043823083 1.32943648312522e-06 312.402279326522 113.320969372426 2.75679144871962 0.00603206229156521 -579.960357572748 221.05415278477 -2.62361213425124 0.00894313404913494 RRP7A essential 0.00877959853455893 1 1 2.75679144871962 -2.62361213425124 4.35466804522132e-17 105.933532373029 13.5782890453971 7.80168488230399 3.1965536564844e-14 -36.5411753850014 31.9431676420038 -1.1439433870344 0.253155832959507 LIN54 essential 4.79797325222485e-13 1 4.027977262536e-10 7.80168488230399 -1.1439433870344 0.00032875233922446 104.490207928329 58.9484696147731 1.77256862834897 0.076864980858756 -307.273521786891 113.157650211965 -2.71544629294892 0.00683097355291629 FAM53B other 1 1 1 1.77256862834897 -2.71544629294892 0.456612872480971 8.17765446983598 6.55575631500313 1.24740061663382 0.212786382207468 6.24322260789174 21.1878021521751 0.294661171699247 0.768364930641032 FAM180A other 1 1 1 1.24740061663382 0.294661171699247 5.39264472486084e-05 798.301330886759 201.392611373282 3.96390575326076 8.36675567738907e-05 3846.13890838368 1997.30412772777 1.92566512780367 0.0546719178704122 S100A14 other 0.30344411866792 1 0.696533557968521 3.96390575326076 1.92566512780367 3.36748020346354e-10 81.051492909445 43.9259951201067 1.84518285101626 0.0655542501250277 -333.419303121402 72.8833642557803 -4.57469693565852 5.91184896733573e-06 KAZN other 2.82902011892972e-06 0.0723373839643199 1 1.84518285101626 -4.57469693565852 1.6755283333292e-16 249.197544361649 88.3271907888142 2.82130046406058 0.00495930734724038 -1170.12584012349 182.23691963494 -6.42090440547126 2.97539086706056e-10 SLC35E2B other 1.81225144532886e-12 4.21523624136469e-06 1 2.82130046406058 -6.42090440547126 1.30049754502501e-07 36.9511376570217 6.69052054590411 5.52290922709189 5.18908004568803e-08 0.8327663321743 17.1443831102302 0.0485737122659947 0.961276979448523 NEMP2 other 0.000933664598812296 1 0.000538616800665787 5.52290922709189 0.0485737122659947 8.96728301842948e-09 47.7100218715423 7.75593734046676 6.15141920018026 1.48741398297108e-09 46.3187300690092 24.9788469623037 1.85431818125593 0.0642336408678674 ALG1L other 6.95592143739575e-05 1 1.64314622698815e-05 6.15141920018026 1.85431818125593 0.991332554870456 0.833975202630747 12.1059871483795 0.0688894835595777 0.945103043796499 3.72909913890653 28.331461795548 0.131623958051205 0.895330668932214 KIAA0408 other 1 1 1 0.0688894835595777 0.131623958051205 3.81818937167119e-76 140.243601762139 6.36550770568595 22.031801428324 4.46128380912081e-77 168.329180470759 71.1812982294291 2.36479503265319 0.0183953547446468 C8orf76 other 5.92659354270802e-72 1 6.94041922184924e-73 22.031801428324 2.36479503265319 0.190673945432921 128.355826217878 70.3994775180008 1.82324969933275 0.0688287173808183 130.91398440387 239.779659223818 0.545976188420848 0.5853120368042 CXCL17 other 1 1 1 1.82324969933275 0.545976188420848 2.53279208403692e-27 1116.1964591994 124.167886512173 8.98941337050115 4.46996316413247e-18 -683.187889733275 269.0366592753 -2.53938586501025 0.0113915509409182 HMGB1 essential 3.37291921831197e-23 1 6.01344144470742e-14 8.98941337050115 -2.53938586501025 0.0841119001790692 -5.6961553528004 3.92535016184771 -1.45112031231353 0.147339087236574 -16.6042601265048 7.72592255897585 -2.14916212267935 0.0320745429346472 MMP23B other 1 1 1 -1.45112031231353 -2.14916212267935 2.60991484637155e-13 4.74529680395073 0.996821774563167 4.76042651258319 2.47983840759162e-06 -16.1317207984711 3.3211203462125 -4.8573129296167 1.5579980525681e-06 SPATA41 other 2.52744153722621e-09 0.0196089634896222 0.0233104810313612 4.76042651258319 -4.8573129296167 0.0308154518299045 39.7460820505064 32.3537058814308 1.22848622646713 0.219802613271474 -123.947170218367 73.8470387801225 -1.67843114992622 0.0938447481424791 RASSF10 other 1 1 1 1.22848622646713 -1.67843114992622 6.91688903814127e-16 117.569294315352 20.6876646697751 5.68306264588299 2.15704206382513e-08 -154.25675520987 40.8314061295978 -3.7778947587615 0.000175577951009148 BLOC1S2 other 7.35126966973654e-12 1 0.000227740501098657 5.68306264588299 -3.7778947587615 4.32510245394418e-11 277.437948165002 39.9680323760855 6.94149628268926 1.16740771585111e-11 -61.5649421733741 272.18533247572 -0.226187581870768 0.821144922667148 SYCP2 other 3.80046752628075e-07 1 1.38279443942564e-07 6.94149628268926 -0.226187581870768 2.81615545617775e-05 37.2336785736705 8.5763458961043 4.34143853626327 1.69112685671706e-05 54.1014144044247 36.5772951747719 1.47909828066618 0.139698222167308 IL1RAP other 0.163891690894743 1 0.149478702865221 4.34143853626327 1.47909828066618 0.000400917831367843 -226.394045324787 111.453225052725 -2.03129200808401 0.0427247908059563 -2517.61217420876 679.776937260522 -3.70358574439824 0.000234909284391091 PTPRT other 1 1 1 -2.03129200808401 -3.70358574439824 0.30483058165788 -374.994533408355 1279.17264333866 -0.293153965855315 0.769516056760608 4222.70577837556 3095.8746205322 1.36397829239275 0.173137431940238 MYBPC1 other 1 1 1 -0.293153965855315 1.36397829239275 0.251601523306301 7.16821904373537 5.7807788391612 1.24000921730047 0.215516590454896 20.6905957167854 14.1950180631421 1.45759558915316 0.145539862685784 PAX5 og 1 1 1 1.24000921730047 1.45759558915316 0.357378631057435 -1.38364133356319 3.94234333969816 -0.350969262273621 0.725747034721065 -21.8477618843905 15.2393555635735 -1.4336407988677 0.152248237516881 ZNF676 other 1 1 1 -0.350969262273621 -1.4336407988677 1.20965379470686e-06 8.05853741379917 1.76537202735995 4.56478141089073 6.21152056171107e-06 -9.97168808042769 6.87850179500401 -1.44968895518357 0.147732308818143 ZNF699 other 0.00801274673613824 1 0.0568292016190946 4.56478141089073 -1.44968895518357 2.41711344468079e-12 110.78145017589 21.7153210202132 5.1015340769207 4.66428886778902e-07 -157.737979575412 45.1527559402793 -3.49342972074709 0.000515750116102611 TDRD7 other 2.25009090565334e-08 1 0.00458452952814983 5.1015340769207 -3.49342972074709 1.11656206439821e-26 82.4565249281141 7.64078733943971 10.7916267349171 1.15959573066812e-24 -64.7162587905159 46.4618488069357 -1.39289030575243 0.164241377335753 CCDC189 other 1.47553676810224e-22 1 1.65706229912475e-20 10.7916267349171 -1.39289030575243 5.07304269705763e-22 92.5347864023456 13.1834719162907 7.01899977410361 7.0961526862369e-12 -59.5836852046927 28.8462931934881 -2.06555777565706 0.0393709265998711 KIAA0895L other 6.25404703693264e-18 1 8.45151784930815e-08 7.01899977410361 -2.06555777565706 0.141141976613077 403.595213726803 399.083328233659 1.01130562259544 0.312318120431426 2706.83250090004 1394.75215839374 1.94072651876542 0.0528057935841732 HLA-DRB1 other 1 1 1 1.01130562259544 1.94072651876542 0.00088553680080714 36.4453945466875 9.72868155487995 3.74618023429972 0.000200639539297169 -1.33502356360644 57.959784593859 -0.0230336184470204 0.981632719718808 MYT1 other 1 1 1 3.74618023429972 -0.0230336184470204 0.00362461783439503 -428.099686728127 2544.81280708381 -0.16822443110018 0.8664689021727 -16614.7616228387 5268.66086323513 -3.15350751436232 0.00170173517569478 SERPINA3 other 1 1 1 -0.16822443110018 -3.15350751436232 0.781567199516851 38.7366668407203 66.551034315111 0.582059576374229 0.560768576821666 139.146405180054 290.681967964727 0.478689497509314 0.632352583012825 AKR1C3 other 1 1 1 0.582059576374229 0.478689497509314 0.00414708801349439 281.351217038493 87.2967480998774 3.22292895396968 0.00134558268305876 -0.192930905655023 216.364863052848 -0.000891692407597155 0.999288862406952 SPATS2L other 1 1 1 3.22292895396968 -0.000891692407597155 2.56312083348806e-36 74.0772944021969 5.42726057185718 13.6491132904732 4.72348244988305e-36 -38.694913780996 37.1734345268928 -1.04092920854549 0.298434608943695 ZNF250 other 3.68653669480588e-32 1 7.0762490581698e-32 13.6491132904732 -1.04092920854549 3.09910793635655e-07 34.694712767713 8.1787523120763 4.24205446550627 2.60169838808988e-05 -42.0292022881528 20.3713989983116 -2.06314756741234 0.0395708027735666 WDSUB1 other 0.00215945841005325 1 0.226529878650986 4.24205446550627 -2.06314756741234 1.29766208498948e-22 13.9364575569549 3.23874218791801 4.30304629029884 2.00028002782774e-05 -55.2574704984789 7.26823917198819 -7.60259385951983 1.29419387768284e-13 ZNF79 other 1.6157190620204e-18 1.91928952060365e-09 0.175784608845501 4.30304629029884 -7.60259385951983 0.0834308159227786 182.16748118675 85.602737815798 2.12805671681603 0.0337863032697908 -687.174794567943 883.817053438845 -0.777507960379599 0.437200892288205 S100A4 other 1 1 1 2.12805671681603 -0.777507960379599 6.14385301385012e-06 84.9275783023658 32.0109548770761 2.65307856727463 0.00821676400525908 -128.064932770128 70.3966904392903 -1.81918968023888 0.0694498186844828 PLEKHG4 other 0.0380058747436769 1 1 2.65307856727463 -1.81918968023888 0.00757189458370092 -44.5081386157653 18.3219714396427 -2.42922213706022 0.0154722696730459 -112.926644242954 40.9181397053131 -2.75981862949381 0.00598937262663983 FAT4 other 1 1 1 -2.42922213706022 -2.75981862949381 0.0494419519521639 1.19789709097255 4.07938688940269 0.293646355064878 0.769141183199101 34.4198521476888 14.0719433166351 2.44599138677595 0.014764107833428 KIF19 other 1 1 1 0.293646355064878 2.44599138677595 0.000536209908064384 30.8058995641036 9.53372133274237 3.23125655648279 0.00130901377846613 -38.1451226323762 34.7826841545754 -1.09666989651684 0.273283752154333 ZNF681 other 1 1 1 3.23125655648279 -1.09666989651684 1.6197736572618e-07 123.69240019961 116.690466795915 1.06000433108165 0.28961302960233 -2230.7982378391 429.608376090757 -5.19263208538521 2.93438621408649e-07 ACADSB other 0.00115489861762766 0.00380736611277722 1 1.06000433108165 -5.19263208538521 2.33519411921019e-12 235.257933807412 49.634323588637 4.73982350917482 2.73829442774981e-06 -364.295655000473 100.013941348757 -3.64244874352208 0.000296041371542473 STK40 other 2.17476628322045e-08 1 0.0256413890214493 4.73982350917482 -3.64244874352208 4.72575078603135e-09 304.41942758055 48.7696087806201 6.24199035407312 8.73451288261496e-10 -148.38397084622 307.775324794634 -0.482117827168994 0.629917233281899 TMEM63A other 3.73003509541455e-05 1 9.74596947442177e-06 6.24199035407312 -0.482117827168994 0.292448581819964 1.62253540439307 2.47425102819437 0.655768305602018 0.512253540794624 32.4241924586837 23.0473104667693 1.40685363289719 0.160048190250436 CTSE other 1 1 1 0.655768305602018 1.40685363289719 1.69666163998207e-05 100.100421363807 21.1413250499735 4.73482249230793 2.80766835749888e-06 1.18647983508234 190.022363214442 0.00624389579737719 0.995020438833809 SEMA4A other 0.101070133893732 1 0.026282583494547 4.73482249230793 0.00624389579737719 1.99845135452976e-05 72.2622041449086 15.522420186505 4.65534390105819 4.07886510209838e-06 82.4504480140671 40.7458423962571 2.02353033254851 0.0435123592219245 HRCT1 other 0.11818841310689 1 0.0377458176548184 4.65534390105819 2.02353033254851 2.97228885635441e-31 116.999576347997 29.0174939488805 4.03203586616105 6.36784182599752e-05 -522.914556708481 60.2728624674251 -8.67578766465744 5.42498265109031e-17 MPHOSPH8 other 4.11662006605085e-27 8.25465360189902e-13 0.535917568075951 4.03203586616105 -8.67578766465744 2.06017776610775e-14 34.0747872079598 5.3749739048438 6.33952607235031 4.84454681608819e-10 -62.7394542643665 18.4942664229704 -3.39237322689601 0.000743304813764499 RNF216P1 other 2.07954343710916e-10 1 5.45883535236817e-06 6.33952607235031 -3.39237322689601 3.03521276110418e-05 -724.910492831376 202.594412652694 -3.5781366491784 0.000377067298945932 -2270.48338008671 610.84852743679 -3.71693354097781 0.000222611966606251 GREB1 other 0.17598163588882 1 1 -3.5781366491784 -3.71693354097781 0.693600636109606 1.98276454103657 2.80741373748515 0.706260183371728 0.480326503408199 -2.65314774932226 10.3841089999038 -0.255500760763089 0.798432224614737 SIRPB2 other 1 1 1 0.706260183371728 -0.255500760763089 4.09976438845722e-37 191.510704332336 13.9186289556754 13.7593081144854 3.68858470017824e-37 -6.47441087336992 58.1123311754994 -0.111411997116708 0.911330892190942 ZNF766 other 5.92046975337107e-33 1 5.5398853611977e-33 13.7593081144854 -0.111411997116708 0.0223987904924372 292.40657036191 106.758295465894 2.7389587767943 0.00636515285477931 92.9221183376337 641.555758991943 0.144838725294337 0.884891752356294 RYR1 other 1 1 1 2.7389587767943 0.144838725294337 9.09123563470198e-05 8.3769456952363 12.6531185044241 0.662045936921189 0.508225783676904 -134.224650639412 32.6913152399093 -4.10581983791069 4.65627408607623e-05 SRGAP3 other 0.496745115080116 0.538451535313856 1 0.662045936921189 -4.10581983791069 4.92902682633589e-17 126.685323939805 14.1926307378557 8.92613401135702 7.6882974801326e-18 35.2068921656812 94.2107816776102 0.373703429042329 0.708778169520644 FAM217B other 5.42045080092158e-13 1 1.03169263885899e-13 8.92613401135702 0.373703429042329 0.623203321978815 -19.2853415468068 23.3587606454892 -0.825614930496366 0.409385141151355 34.1187837666392 92.184674363309 0.370113405533914 0.711442309214953 SULT1C3 other 1 1 1 -0.825614930496366 0.370113405533914 9.53702456682869e-19 5430.80661953723 584.513622257507 9.29115492392185 3.72627794071444e-19 1944.71459986586 2270.05222985784 0.856682755703664 0.392000239229429 TUBB essential 1.09628097395696e-14 1 5.074817927459e-15 9.29115492392185 0.856682755703664 1.02311145968731e-11 124.309178656292 48.8144332615624 2.54656605332702 0.0111522527143643 -494.048983295931 94.3793702414101 -5.23471370949201 2.36100582811975e-07 LCOR other 9.26836671330736e-08 0.00307332128646348 1 2.54656605332702 -5.23471370949201 2.78408989628845e-68 996.14588237695 49.8634941472845 19.9774584475484 6.40520305280843e-67 -33.1166762019977 278.281141265898 -0.119004385461948 0.90531605635284 SUPT5H essential 4.30392457067232e-64 1 9.92742421154779e-63 19.9774584475484 -0.119004385461948 6.61994947144583e-45 132.808147548141 15.9974242367113 8.30184569609455 8.21139615403359e-16 -230.191323649093 29.9373939075214 -7.6890902514818 7.01821478702544e-14 XPNPEP3 other 9.88226057097434e-41 1.04381908527429e-09 1.06501808117816e-11 8.30184569609455 -7.6890902514818 0.00408595254746856 62.6693947297421 32.2277894118374 1.94457627635867 0.0523679276955717 -292.420583111563 131.171965721961 -2.22929176598141 0.0262233645416608 ZNF107 other 1 1 1 1.94457627635867 -2.22929176598141 5.32122089596474e-11 1245.8242484788 185.441528778211 6.71815130454846 4.70349901129708e-11 -503.006843701753 729.8237428566 -0.689216880959417 0.490984481340976 PPIA essential 4.65287555143157e-07 1 5.46452515132494e-07 6.71815130454846 -0.689216880959417 0.0126132440665536 17.7174862876488 7.8286561691237 2.26315805738497 0.0240199600224549 -44.7832673988208 31.515206713084 -1.42100503438007 0.155889297113168 ZNF471 other 1 1 1 2.26315805738497 -1.42100503438007 1.12425982519962e-05 35.891896476176 8.33315937271287 4.30711748940082 1.96381152515471e-05 -48.4364479193802 35.1936401082004 -1.37628411754129 0.169302019181468 ZNF836 other 0.0680685703210625 1 0.172717223637357 4.30711748940082 -1.37628411754129 9.59205097834094e-05 10.27008384179 10.984225213587 0.934984820694167 0.350211726350365 -136.546242726586 36.6530355977209 -3.72537336948638 0.000215435573965317 ZNF493 other 0.522670857809798 1 1 0.934984820694167 -3.72537336948638 6.54243279273713e-08 5.37181840378779 13.1209220504376 0.409408605823449 0.68241445225457 -277.737424440272 49.8676198539408 -5.56949429817882 4.16980574222463e-08 GTF2IRD2 other 0.000479625748035559 0.000558837365572945 1 0.409408605823449 -5.56949429817882 4.45689990783645e-29 24.057052034306 2.10112374508977 11.4496121851587 2.92573588770041e-27 -15.2178826078544 10.9960611250904 -1.38393943383335 0.166962823246079 SUPT3H other 6.04979593489719e-25 1 4.24436505228698e-23 11.4496121851587 -1.38393943383335 1.50906831111535e-15 74.0854282004637 11.3031953127208 6.55437919550824 1.30859948022511e-10 -103.117890140528 28.3298468767794 -3.63990284130512 0.000299012631501177 NIF3L1 other 1.58572898132001e-11 1 1.50253392319447e-06 6.55437919550824 -3.63990284130512 0.393683961776011 411.06943353309 306.591182785279 1.34077382721401 0.180562894737914 156.075784177335 1836.91827855993 0.0849661011047766 0.932320125909232 ATP2A1 other 1 1 1 1.34077382721401 0.0849661011047766 2.3204846048724e-10 789.639837683993 121.571231244817 6.4952853532744 1.87490143399157e-10 67.1839066693871 267.637626933338 0.251025640300274 0.801889247450541 IARS essential 1.96985938107618e-06 1 2.14132492776177e-06 6.4952853532744 0.251025640300274 1.14251983528155e-06 31.1875096882947 7.2631716833589 4.29392434158624 2.08210148117786e-05 -22.4014269847955 14.9714983886755 -1.49627154231536 0.135168199117583 MFSD14C other 0.00758290414676362 1 0.182787689032604 4.29392434158624 -1.49627154231536 8.14878406290116e-14 221.113647413501 36.9439324612429 5.98511400066755 4.01757786285348e-09 -560.285018602584 141.44035206716 -3.96128127803687 8.48868021466862e-05 POM121 other 8.04284987008345e-10 0.961682581519808 4.36308955905888e-05 5.98511400066755 -3.96128127803687 4.91473166808162e-29 183.1964830318 50.5355916595454 3.62509821327474 0.000316185812473907 -714.697239468384 96.5400737310098 -7.40311470508868 5.13690277946997e-13 ZBTB44 other 6.6658505614191e-25 7.57025362610489e-09 1 3.62509821327474 -7.40311470508868 0.452258552072842 -11.3975314810276 15.1365472114798 -0.75298093559828 0.451786497218025 32.763974085358 46.9161301691071 0.698352015975351 0.485254941727463 GIMAP5 other 1 1 1 -0.75298093559828 0.698352015975351 2.96749796811215e-12 12.1622619942268 1.6309926227195 7.45696934787332 3.55907774661676e-13 9.28136096856132 8.88531010496909 1.04457366810087 0.296688294800678 STK31 other 2.75383811440807e-08 1 4.37375064281734e-09 7.45696934787332 1.04457366810087 9.93709091425023e-08 -2.03101119932243 3.62278430972273 -0.560621617431558 0.575288467357447 -36.8708348287049 6.94677156691256 -5.30762160142426 1.62547710398516e-07 ZKSCAN7 other 0.000718749785827719 0.00213116303103494 1 -0.560621617431558 -5.30762160142426 3.06790130355268e-06 249.307373121627 48.8891032942692 5.09944663171703 4.7444151049529e-07 -6.79225865969976 378.650351465427 -0.0179380756769743 0.985694979199408 CD55 other 0.0195824140205767 1 0.00466091339910573 5.09944663171703 -0.0179380756769743 0.880025495205569 2.37080626270226 4.69540812220366 0.504920169024538 0.613818635320796 1.90242172580982 16.0315636451939 0.118667259658115 0.90558262106609 CPNE4 other 1 1 1 0.504920169024538 0.118667259658115 2.92046672904948e-35 23.3076746090622 1.87388252139988 12.4381728005288 2.05200147394987e-31 -21.3326481697925 8.6232289658015 -2.47385848785817 0.0136720576258513 ZNF565 other 4.17626742254076e-31 1 3.03203737790832e-27 12.4381728005288 -2.47385848785817 0.441101750119403 1.93584446599657 2.00369979674086 0.966134981470445 0.334407525324293 -2.10610543646604 4.62382768867135 -0.455489602613463 0.648939462781921 NTNG2 other 1 1 1 0.966134981470445 -0.455489602613463 2.19040552283172e-14 212.618098322488 28.7930367544468 7.38435824382614 5.7723190167804e-13 -44.1240607496005 67.4314337667464 -0.654354479577448 0.513159484982136 WDR5 essential 2.20749068590981e-10 1 7.05435107040733e-09 7.38435824382614 -0.654354479577448 1.47080572576442e-13 363.63216554188 63.3977760297482 5.73572431580649 1.61385280304028e-08 -488.308020200325 157.329447401109 -3.1037293289119 0.00201051734280489 LONP1 essential 1.43771259693472e-09 1 0.000171342752098786 5.73572431580649 -3.1037293289119 1.79819642655295e-11 286.97387170115 62.3464006771858 4.60289396956578 5.20146860903937e-06 -764.179155671642 192.665918011161 -3.96634320984252 8.28410556690754e-05 TRRAP essential 1.60866652319427e-07 0.939251889175976 0.0478374473592474 4.60289396956578 -3.96634320984252 3.45029974645077e-13 52.379585949685 8.61760694304808 6.0782055036683 2.30101823350264e-09 -13.0022381489551 17.4934933502657 -0.743261388026743 0.457647280733362 FUT4 other 3.32160356590816e-09 1 2.52214608574224e-05 6.0782055036683 -0.743261388026743 0.000136735417962153 -53.9718377815073 58.8473109507573 -0.917150451048992 0.359470222530919 -1080.32355823687 254.595979724398 -4.24328600713307 2.58941237492779e-05 ASB13 other 0.730440602753819 0.304255954054015 1 -0.917150451048992 -4.24328600713307 0.582442571515333 1.17024743869539 1.46200414938256 0.800440572750505 0.423810875482953 -1.3863255643466 4.6136755157422 -0.300481808834705 0.763926397109737 SLC35F1 other 1 1 1 0.800440572750505 -0.300481808834705 3.51542055009024e-39 31.7961733264478 2.24584742851637 14.1577619755999 2.83372872786562e-38 -24.989758404858 15.2374968724854 -1.64001729509671 0.10165670758555 ZNF34 other 5.12899858258166e-35 1 4.26702871842004e-34 14.1577619755999 -1.64001729509671 7.78737877904486e-07 4.60456901393518 0.974374824110128 4.72566501103969 2.92675011195904e-06 -7.68630625151998 5.07007740779308 -1.51601358979363 0.130098894090219 ZNF781 other 0.00525414446222157 1 0.027368040296929 4.72566501103969 -1.51601358979363 4.33442927325506e-08 38.1560055388968 16.235414509786 2.35017131936471 0.0191332917034239 -176.102980639317 39.432453786187 -4.46594020230629 9.76295567113754e-06 ZNF140 other 0.000321788029246455 0.117956030418684 1 2.35017131936471 -4.46594020230629 6.44523708907955e-30 9.28339293838013 3.11023753050784 2.98478583944819 0.0029658103011182 -55.7528168353109 5.78811513925732 -9.63229229100385 2.24125740504161e-20 INCA1 other 8.81192814818956e-26 3.45512241561214e-16 1 2.98478583944819 -9.63229229100385 9.28552474090468e-18 13.9908001934372 1.61815505320421 8.64614312808472 6.007644338778e-17 -19.3637421187781 10.0771167930454 -1.92155578986062 0.055184766774143 ZNF774 other 1.0418358759295e-13 1 7.95231881124044e-13 8.64614312808472 -1.92155578986062 0.000333298911096006 425.677696375721 116.428934654511 3.65611604743158 0.000281700463421858 -1191.33590567424 886.504219017195 -1.34385813413837 0.17957144740945 PTPN1 other 1 1 1 3.65611604743158 -1.34385813413837 2.06800016009378e-15 405.1356194642 482.087642990102 0.840377523371861 0.401067309908833 -7443.30220167267 995.615944439493 -7.47607774186768 3.09775870688815e-13 EVL other 2.1631281674581e-11 4.5753896100738e-09 1 0.840377523371861 -7.47607774186768 3.85004340454592e-12 7.98452511347387 1.13136823206801 7.05740614519386 5.16048820125319e-12 26.4267995314629 14.3572607239597 1.8406574930663 0.0662132152709114 THEM5 other 3.55397506673634e-08 1 6.16936364459819e-08 7.05740614519386 1.8406574930663 2.00801280354822e-05 23.0171001148118 5.15133579117507 4.46818088509066 9.6085602023108e-06 67.0965924546576 23.5598446696609 2.84792168180382 0.00456758575008043 NOXO1 other 0.118733797073807 1 0.0867076472656526 4.46818088509066 2.84792168180382 1.63745173738679e-10 432.02367519017 99.1048312201773 4.35925948181436 1.56292817197486e-05 -1202.97027084583 319.559781837043 -3.76446079644426 0.000185209264371336 EPHB4 other 1.39952999994449e-06 1 0.138522323882132 4.35925948181436 -3.76446079644426 1.73817182677658e-17 75.0529040963998 8.49338949152288 8.83662572772731 1.36999563780513e-17 -20.2928895058665 35.633155269457 -0.569494599970511 0.56925604230106 ZNF765 other 1.93388997447162e-13 1 1.83058817123521e-13 8.83662572772731 -0.569494599970511 1.42614011238894e-08 21.2324973911999 3.4739005555203 6.11200495001501 1.87968398536911e-09 7.89758581607401 21.8724299093983 0.36107491708914 0.71818387940009 ZNF124 other 0.000109242332608993 1 2.0685922258987e-05 6.11200495001501 0.36107491708914 3.93325273180194e-57 1695.78236743629 142.831567949362 11.8726020569731 4.59025769437793e-29 -1684.47350682522 268.459348399504 -6.2745943356701 7.16970660535123e-10 XRCC6 essential 6.02102328184242e-53 1.00770226338212e-05 6.71646505841378e-25 11.8726020569731 -6.2745943356701 9.24813508760844e-21 99.953831211785 28.6090725507693 3.49378089885326 0.000515382810562675 -517.359293242869 68.1395050838033 -7.59264823844229 1.3907943205857e-13 PPP1R26 other 1.11255065103929e-16 2.06199165970036e-09 1 3.49378089885326 -7.59264823844229 0.0608911882182504 20.649550625378 18.7335498804825 1.10227643757426 0.2708399154914 -65.5787230970366 43.3409192364275 -1.51309026786673 0.130850548348924 NBPF4 other 1 1 1 1.10227643757426 -1.51309026786673 6.04632582422482e-10 99.1020378176179 16.2654290208663 6.09280195994116 2.10341575251091e-09 -148.091283735274 64.4532488094236 -2.29765429161147 0.0219608294532357 TSC22D2 other 5.01240410828238e-06 1 2.30976083783223e-05 6.09280195994116 -2.29765429161147 1.098988226097e-05 23.6098060442069 6.69706580674639 3.52539555762215 0.000458367347129383 -8.46355081292189 14.6168757531647 -0.579025980369948 0.562810434467701 NPIPB15 other 0.0665876966192172 1 1 3.52539555762215 -0.579025980369948 1.32757114659405e-18 43.9718771174552 4.98125789628685 8.82746447443182 1.51165639688139e-17 -31.6120467578575 24.3313954482292 -1.2992286786477 0.194422986389552 ZNF569 other 1.52059999130882e-14 1 2.01836362111604e-13 8.82746447443182 -1.2992286786477 3.0269831812185e-19 137.918274646773 15.608584523279 8.83605265045516 1.3822727619568e-17 -24.255901833663 32.4751233323604 -0.746907150603268 0.455443485478859 YRDC essential 3.52401381957458e-15 1 1.84685463725048e-13 8.83605265045516 -0.746907150603268 2.21388766440701e-17 49.3733447795101 10.98731345259 4.49366853804207 8.57596871187135e-06 -206.191395366339 34.1724706929627 -6.03384511523779 2.98170337491742e-09 ZNF777 other 2.45652975242601e-13 4.13174636662307e-05 0.0777068524982663 4.49366853804207 -6.03384511523779 7.56400956474932e-12 133.941817801612 23.4064390487009 5.72243464812925 1.73447992162805e-08 -276.925887249854 79.5476055841108 -3.48125987220372 0.000539070132187393 PIK3R4 other 6.89913312400786e-08 1 0.000183889561291006 5.72243464812925 -3.48125987220372 9.4866433556835e-13 24.3607171017784 6.03013967683413 4.03982634023627 6.11609721682627e-05 -88.6956259931707 18.6328102845443 -4.76018510566507 2.48047738949504e-06 ZNF775 other 8.97151862146988e-09 0.0309538773435086 0.515586995378455 4.03982634023627 -4.76018510566507 2.2341940339409e-05 19.4551304462346 18.8857240265357 1.03015009744391 0.303411201763938 -184.310587908143 45.6757826864729 -4.03519276666336 6.26233974239489e-05 ZNF605 other 0.131173674875024 0.716912653709367 1 1.03015009744391 -4.03519276666336 0.063326518134768 -0.343580160698665 0.82415367863496 -0.41688846340859 0.67692444420123 -7.30597359147865 3.10237328226028 -2.35496277422676 0.0188788092373527 RFX8 other 1 1 1 -0.41688846340859 -2.35496277422676 0.000750416915893162 226.846664855139 83.1072205477146 2.72956625621836 0.00654946431042782 -454.021081911281 244.640552352572 -1.85587008182091 0.0640186896319136 MYL6B other 1 1 1 2.72956625621836 -1.85587008182091 1.15555731022338e-11 18.9450386875528 5.43160847861408 3.48792420553604 0.000527475911792336 -105.224778989816 19.8929733423557 -5.28954506593409 1.80065262928012e-07 ZNF799 other 1.04381491832478e-07 0.00235471344330962 1 3.48792420553604 -5.28954506593409 1.30315377720221e-29 70.7954975675987 17.6414357298811 4.01302357991674 6.9203017430523e-05 -351.721890469375 47.1109703391417 -7.46581715335951 3.74922720740751e-13 SIAH1 other 1.77671985983749e-25 5.533109512692e-09 0.580267301154936 4.01302357991674 -7.46581715335951 2.7053525203121e-10 28.4627330111655 13.1130155694925 2.17057112914471 0.0304010586332824 -268.135661225337 48.5310062857936 -5.52503815079202 5.14213635939531e-08 C20orf96 other 2.28439966815154e-06 0.000687040838978808 1 2.17057112914471 -5.52503815079202 0.404910191126287 -35.8941609365689 31.7241661626749 -1.13144537046336 0.258381304991284 -166.736275409695 195.257712425519 -0.853929267830059 0.393531427564113 ESRRG other 1 1 1 -1.13144537046336 -0.853929267830059 2.08789854099376e-34 505.222733018881 41.0063760403247 12.320589669325 7.32285235111499e-31 -194.606750604432 117.395507028475 -1.65770186210985 0.097967164791414 IPO4 other 2.96627745718983e-30 1 1.08026717883648e-26 12.320589669325 -1.65770186210985 1.7986070791607e-07 366.462509513001 132.446031142296 2.7668817732959 0.00585353417611288 -1201.48916180249 305.300538949823 -3.93543085752612 9.38991181875231e-05 NCOR2 other 0.00127755060832785 1 1 2.7668817732959 -3.93543085752612 1.1387734292035e-09 163.791699575532 32.272182396789 5.07532145058243 5.35601695925243e-07 -542.747475067863 194.202349928694 -2.79475235632908 0.00538142352970529 SULT1A1 other 9.28783608858375e-06 1 0.00524139819632443 5.07532145058243 -2.79475235632908 3.77812547548307e-07 21.8183176105661 5.20664008555589 4.19047932102967 3.25636094749641e-05 61.6125084892224 12.768245778652 4.82544819056005 1.82474735324389e-06 ARL9 other 0.00261672970431958 0.0228896307990914 0.28167522195844 4.19047932102967 4.82544819056005 1.83423086395948e-09 383.383479058114 79.8006284746728 4.80426641226005 2.02193078182134e-06 -504.510950669077 195.623537599519 -2.57898899518888 0.0101759329905921 PRPF40A essential 1.48315907659763e-05 1 0.0190930923727389 4.80426641226005 -2.57898899518888 5.03091748486825e-32 149.299724538608 12.6106110797678 11.8392141026489 7.52601225693794e-29 -37.2086024737515 38.2821878892936 -0.971956006834124 0.331516639902724 GDAP2 other 7.0146082491518e-28 1 1.10052877233203e-24 11.8392141026489 -0.971956006834124 3.11185185357162e-24 203.143296635262 27.1457915405205 7.4834176904376 2.95921794155614e-13 -321.904013087004 60.9479453635972 -5.281622065627 1.85958260798257e-07 ANAPC7 other 3.97539074293775e-20 0.00243066042689401 3.64605242579132e-09 7.4834176904376 -5.281622065627 0.0424751711938485 -2.23544816301834 2.61921718935948 -0.853479494598543 0.393771176757053 -21.4099012088628 8.49539992254101 -2.5201757897301 0.0120162753894831 TPK1 other 1 1 1 -0.853479494598543 -2.5201757897301 0.00016766195984211 205.77444039221 61.8275986199334 3.32819719648417 0.000933335765881003 -180.155672958793 135.291762224368 -1.33160859166002 0.183547551488373 SLC6A9 other 0.884416838167132 1 1 3.32819719648417 -1.33160859166002 0.39937917412123 -42.6378404145659 47.9972937252923 -0.888338427132982 0.374750625343397 -139.194966900382 106.479512917599 -1.30724646541256 0.191680262011862 AFAP1 other 1 1 1 -0.888338427132982 -1.30724646541256 8.77581641607902e-10 552.953117139726 269.754803773676 2.04983603407356 0.0408664585650023 -4419.68310694189 799.487100894732 -5.52814811145255 5.06071793654092e-08 NACA essential 7.20319011431766e-06 0.000676263737859963 1 2.04983603407356 -5.52814811145255 5.02116465366181e-44 619.138384655152 40.8369991907991 15.161211570968 4.62005482803879e-43 177.012474789368 161.749590828564 1.09436119054533 0.274318291714794 MYO18A other 7.47299935404488e-40 1 7.02063531668775e-39 15.161211570968 1.09436119054533 0.283399691473321 -51.2596837825114 72.779100646899 -0.704318730609314 0.481539054780567 -398.539503341405 274.294775735413 -1.4529606051478 0.146817690966895 SPTSSB other 1 1 1 -0.704318730609314 -1.4529606051478 5.07169596866554e-30 30.2495292244406 11.0248791169873 2.74375155531925 0.00627386814855186 -189.157351507444 19.6582524806398 -9.62228721468168 2.37778250880161e-20 BORCS6 other 6.93960159392506e-26 3.6651139590668e-16 1 2.74375155531925 -9.62228721468168 1.1080468641863e-18 319.756052201358 37.2229578553577 8.59029133159911 9.60900320455195e-17 -154.488139198039 94.3149550454201 -1.63800257470982 0.102011324609231 MAN2A2 other 1.27137297196736e-14 1 1.26723534261631e-12 8.59029133159911 -1.63800257470982 0.0369767715648458 265.426856537649 115.443368944956 2.29919534541828 0.0218718511650928 559.813576770103 444.307750807971 1.25996806436999 0.208221121665575 MME other 1 1 1 2.29919534541828 1.25996806436999 1.35820095345024e-05 337.179756684073 89.0176455214918 3.78778560934491 0.000169136255121681 -596.232091463706 402.401929764377 -1.48168298251657 0.139010112256393 CACNA1H other 0.081641459311894 1 1 3.78778560934491 -1.48168298251657 0.0129133954382098 450.915362350515 233.927188464922 1.92758851721989 0.0544363727754966 -2975.48836038594 1528.09858293424 -1.94718350871868 0.0520365647465221 SULF2 other 1 1 1 1.92758851721989 -1.94718350871868 0.00250392545245471 -191.338192931964 55.0520917926941 -3.47558442742691 0.000550659122443044 -227.739153087317 131.120991951087 -1.73686264646528 0.0829806042136292 LAMA2 other 1 1 1 -3.47558442742691 -1.73686264646528 2.32063615691298e-31 1436.03641292817 193.158073281758 7.43451406679458 4.24445309778694e-13 -2584.28898319188 412.444488271744 -6.26578620075822 7.68496167809493e-10 PLXNB2 other 3.21732996794416e-27 1.07942971730521e-05 5.20115282602812e-09 7.43451406679458 -6.26578620075822 0.0785008570509516 14.6779845632997 16.5010672637893 0.889517285679441 0.374118316862286 62.3077455198673 27.7089375854121 2.248651552511 0.0249340805909412 AJAP1 other 1 1 1 0.889517285679441 2.248651552511 8.55387716960508e-08 56.3839354401304 10.0115751914076 5.63187454143296 2.86578155918834e-08 20.8869344256035 28.0601746787164 0.744362238109879 0.456979955887222 XRCC2 other 0.000621866870230289 1 0.000301050352792735 5.63187454143296 0.744362238109879 1.41224887515269e-12 415.067321002831 238.886916638946 1.73750545589805 0.0828777874238509 -2881.05488738998 530.377422994717 -5.43208432802895 8.49442035566738e-08 MYO6 other 1.32694904309347e-08 0.0011271246369935 1 1.73750545589805 -5.43208432802895 1.10458435367824e-18 117.897842682612 31.1486671161169 3.78500441906902 0.000170989036872847 -332.511895586525 58.3856228216408 -5.69509888765422 2.03071397849248e-08 MKL1 other 1.26751054584579e-14 0.000274714987010463 1 3.78500441906902 -5.69509888765422 5.16930060086473e-48 1043.86149064021 76.289963723151 13.6828154018828 8.57833563630703e-37 -507.533007439573 218.891308027207 -2.31865308866668 0.0207870126947691 HDAC2 other 7.77876354418124e-44 1 1.28726504558423e-32 13.6828154018828 -2.31865308866668 1.86674552727911e-13 12.6971835179303 4.23539533938927 2.99787446046565 0.0028440731475093 -51.1758147267861 8.73037527728464 -5.8618115603735 7.98278896323504e-09 ZNF782 other 1.81765011991167e-09 0.000109507898997658 1 2.99787446046565 -5.8618115603735 0.216374261678077 14.3534967926423 8.25388041230504 1.73899984923986 0.0826057266993948 15.4829706987688 23.0472264395298 0.671793230278369 0.502003170160934 POTEF other 1 1 1 1.73899984923986 0.671793230278369 5.03980907376792e-22 15.4513140549154 2.2817186676321 6.77178754510972 3.36328617094394e-11 -50.7089308543011 8.51902178508289 -5.95243587040642 4.78824279380924e-09 ZNF846 other 6.21408458795585e-18 6.60538093405985e-05 3.92697293319415e-07 6.77178754510972 -5.95243587040642 0.530797600844732 186.524456616106 165.850074915182 1.12465705373662 0.261231286088762 193.710371361244 334.649837137957 0.578844959310076 0.562933814439682 MMP1 other 1 1 1 1.12465705373662 0.578844959310076 0.427130511658723 343.217179001582 578.812928475889 0.592967368412675 0.553449411280361 -1097.7522732477 1302.35281939174 -0.842899294954801 0.39965521030531 ADH1B other 1 1 1 0.592967368412675 -0.842899294954801 0.273420801464426 -20.5277928731979 17.8174735055284 -1.15211580737463 0.249796847656021 -72.7920363729568 49.732055825024 -1.46368444186314 0.143877512486063 UGT2B15 other 1 1 1 -1.15211580737463 -1.46368444186314 0.0051013525480019 -165.46826807723 82.2709289164361 -2.01126048115122 0.04479435309781 -548.573202274265 172.107308934414 -3.18739050462588 0.00151871489779124 TCF4 other 1 1 1 -2.01126048115122 -3.18739050462588 3.44587174991954e-07 40.5240078938197 9.10556642887394 4.45046535109746 1.0416822059244e-05 -56.0253206690289 28.6465673679336 -1.95574289755018 0.0510116513610533 SDHAF3 other 0.00239557004054406 1 0.0937722321773147 4.45046535109746 -1.95574289755018 0.92995494514094 2.79190873256772 7.49861000750336 0.372323501258773 0.709796208039456 -0.0244101407691786 20.4101884920457 -0.00119597821346391 0.99904618370638 HRH1 other 1 1 1 0.372323501258773 -0.00119597821346391 9.91738333411243e-10 458.754571880277 89.1503431453967 5.14585312512019 3.80380873990425e-07 -455.21856592205 207.091172784761 -2.19815533323179 0.0283857390017879 RABL6 other 8.11638652063761e-06 1 0.00375968455852136 5.14585312512019 -2.19815533323179 4.50864436351741e-21 46.6370228351212 6.64298083588446 7.0204963686173 6.88249854543889e-12 -125.024799575646 23.9186392390306 -5.22708663842505 2.49126096681371e-07 ZNF136 other 5.45681227316512e-17 0.00324063226563127 8.20049701689043e-08 7.0204963686173 -5.22708663842505 2.90275443050597e-18 44.2909521645257 8.59512705253239 5.15303053623578 3.6001610256039e-07 -163.449396576547 27.2477165364229 -5.99864566111655 3.64717243926331e-09 ZKSCAN5 other 3.29781930849783e-14 5.04367476625724e-05 0.00356271935093762 5.15303053623578 -5.99864566111655 0.0945142196235993 8.11282594971307 6.99400645527067 1.15996832453583 0.246573357031209 -14.2357489393691 13.3887409776414 -1.06326270432314 0.288137196938482 ZNF502 other 1 1 1 1.15996832453583 -1.06326270432314 6.63730309257516e-10 -7.18537031450401 13.6778487303188 -0.525328979445186 0.599570944219343 -212.658438264731 32.8148789437466 -6.48054922370074 2.06773550314676e-10 TTC30B other 5.48307608477634e-06 2.93928601772313e-06 1 -0.525328979445186 -6.48054922370074 1.41836194776038e-21 63.9178487754627 19.0600725242684 3.35349452076213 0.000854059282976977 -307.317600558326 39.9957271637378 -7.68376080025258 7.34566541774374e-14 TECPR2 other 1.73224544679975e-17 1.09230044761849e-09 1 3.35349452076213 -7.68376080025258 1.35374792232519e-05 2.20383903154986 4.83881284573449 0.455450355657503 0.648968011160755 -46.6382566363003 10.6314626907037 -4.3868146832779 1.38305413229167e-05 LINC00173 other 0.0814008625694136 0.165607874633475 1 0.455450355657503 -4.3868146832779 1.93549032565999e-31 130.766212905337 19.578651069859 6.67902055349716 6.13222216084351e-11 -413.122512330366 52.0027258586227 -7.94424725837452 1.19419230860348e-14 ZFP62 other 2.68529927782067e-27 1.78746704751768e-10 7.1041793733372e-07 6.67902055349716 -7.94424725837452 4.49948403170833e-27 138.153806462661 14.3309999599241 9.64020702316663 2.06080557903113e-20 -289.516077302362 76.6348631630167 -3.77786382532591 0.000175599194959791 ERI2 other 5.97711458772135e-23 1 2.84535426296827e-16 9.64020702316663 -3.77786382532591 2.94473289957169e-07 227.239629985394 60.2854986898093 3.7693912288032 0.000181646778365261 -831.087811456841 270.11631397337 -3.0767775527204 0.00219840821377929 TOMM7 other 0.00205512909061108 1 1 3.7693912288032 -3.0767775527204 0.0911735447968386 22.3081092220168 36.5258752400139 0.6107481087155 0.541620500324709 -234.999835431491 126.052175807077 -1.86430606157214 0.0628151358104833 HSH2D other 1 1 1 0.6107481087155 -1.86430606157214 1.23243456956438e-29 22.6067365949963 9.54776749114368 2.3677510597075 0.0182428222491871 -177.42035371865 17.6437340062288 -10.055714604177 6.04260522201273e-22 TRPV1 other 1.68091750942885e-25 9.35878696785331e-18 1 2.3677510597075 -10.055714604177 1.69002443024249e-10 -10.2041077854492 27.8706809189896 -0.366123375855403 0.714423952076606 -541.759047877604 81.0187286308273 -6.68683719225219 5.97103091446604e-11 ZNF33B other 1.44378787075616e-06 8.56723515607587e-07 1 -0.366123375855403 -6.68683719225219 9.52779228638101e-45 314.950604183559 19.958208129839 15.7805050500844 6.76393359332996e-46 174.141376922366 151.000302171809 1.15325184398788 0.249352577459751 ZNF512B other 1.42154660912805e-40 1 1.03163515165468e-41 15.7805050500844 1.15325184398788 1.00165930336131e-83 454.922842137963 20.2651649632654 22.4485141355918 1.0610042497307e-78 -448.228661726477 107.96197399667 -4.15172717887041 3.85135222247971e-05 AMZ2 other 1.55948336940322e-79 0.447373074163244 1.65166531555579e-74 22.4485141355918 -4.15172717887041 3.87675581892253e-05 44.1431548739749 15.0930509967915 2.92473369919434 0.00359100130894882 -129.121764829661 53.1997750184598 -2.4271111068582 0.0155426514371214 ZNF431 other 0.222331946215207 1 1 2.92473369919434 -2.4271111068582 1.8498384776767e-27 557.920191570634 71.8153159217391 7.76881901039924 4.3069884029081e-14 -868.840364768128 177.269910584669 -4.90122865128398 1.27737561746364e-06 NF1 ts 2.46842446461179e-23 0.016142195677888 5.41086953057344e-10 7.76881901039924 -4.90122865128398 1.38094669712999e-07 325.481434002755 60.2216954892208 5.40472053067676 9.84961023234612e-08 -148.016548533481 231.482821448134 -0.639427788237173 0.522822519766047 VKORC1L1 other 0.000989586403163353 1 0.00100627310740594 5.40472053067676 -0.639427788237173 4.14330595490051e-29 60.5492446042895 5.03581494167153 12.0237231323261 1.29445529946912e-29 3.37028620038201 24.9130641874629 0.135281881627313 0.892440371764453 ZNF418 other 5.62578082556392e-25 1 1.89948370644098e-25 12.0237231323261 0.135281881627313 0.00437957991573569 120.65127161862 47.1591450814735 2.5583854713689 0.0107866195991878 292.359297139748 102.663390869701 2.84774635498653 0.00457006494324384 DAPK1 other 1 1 1 2.5583854713689 2.84774635498653 0.0100462813584144 247.16502378867 161.096558038857 1.5342663232386 0.125543370462685 1681.52248871551 563.014679237478 2.98664058101095 0.00294722604662752 HLA-DQA1 other 1 1 1 1.5342663232386 2.98664058101095 0.0002556938617383 122.73794526199 56.7084826945153 2.16436658908987 0.0308713642428874 530.064435577026 133.375507356723 3.97422619851282 8.01467263605687e-05 COL27A1 other 1 0.909905784371537 1 2.16436658908987 3.97422619851282 3.57388092036519e-06 246.201536688392 81.3901295723067 3.02495570386907 0.0026032960709549 -526.367208673455 190.296766957005 -2.76603337560843 0.00586570925103795 GM2A other 0.0226512572732746 1 1 3.02495570386907 -2.76603337560843 0.473549729377029 4.25361980430756 3.47791224475812 1.22303827841504 0.221860827083625 4.17637797778789 13.3345075676141 0.31320076550342 0.75425181605208 HIST1H2AI other 1 1 1 1.22303827841504 0.31320076550342 0.110331714405322 -5.97254476709595 3.28559973878213 -1.81779438822021 0.0696434623954917 -17.5577744510339 10.9528683010643 -1.60302981542542 0.109506371237809 CLPSL2 other 1 1 1 -1.81779438822021 -1.60302981542542 0.983703923285855 -11.4403946727744 210.948676632343 -0.0542330715480788 0.956769567307163 379.225499839915 2170.40416879286 0.17472575167916 0.861360743021707 S100A2 other 1 1 1 -0.0542330715480788 0.17472575167916 1.74724423958291e-08 74.1675763448124 12.6512738462577 5.86245916783717 8.00150338372087e-09 -73.4540487661976 90.3200150739604 -0.813264354595693 0.416429640623974 SNHG17 other 0.000133262318152989 1 8.59361463411622e-05 5.86245916783717 -0.813264354595693 3.71937141492463e-28 91.2069888892229 9.32927488642463 9.77642850056241 7.467765792277e-21 -139.293773378368 34.0056971371232 -4.09618931841582 4.86228277759501e-05 ZNF700 other 4.99995099308318e-24 0.561593660812224 1.03518169412544e-16 9.77642850056241 -4.09618931841582 2.21741058873883e-05 471.354853551809 105.726296428438 4.45825560409041 1.00584146510999e-05 -305.639342638207 360.195774025723 -0.848536725520772 0.396515803612718 CD47 other 0.130250697982519 1 0.0906263160064099 4.45825560409041 -0.848536725520772 6.67721170380477e-07 274.42480939258 53.6645631173294 5.11370620483003 4.3941032579142e-07 -2.46887178554732 118.650567818445 -0.0208079222117597 0.983406564235464 TLE1 other 0.00452915269869078 1 0.0043273128883939 5.11370620483003 -0.0208079222117597 1.20059524047584e-11 -11.2452421065116 17.3743267966371 -0.647233256179353 0.517755014233631 -268.962577558082 38.6502548444669 -6.95888238358114 9.93618720990386e-12 MAML3 other 1.08353720452945e-07 1.44273438287804e-07 1 -0.647233256179353 -6.95888238358114 0.0634903329739047 15.7992322457816 9.83499143096773 1.60643070781272 0.108770434642191 81.427028054428 38.6628884720235 2.10607720406996 0.0356637692528868 HIST1H2AG other 1 1 1 1.60643070781272 2.10607720406996 2.9304582163926e-72 343.361940239061 17.03254785103 20.1591648672983 1.88725332127279e-67 -219.267559290686 71.7738270631634 -3.05497934640887 0.00236445068469506 STRN3 other 4.54103805212197e-68 1 2.92562009863708e-63 20.1591648672983 -3.05497934640887 8.24509773284716e-12 70.6337459461456 13.1573588275818 5.36838334134933 1.19465141815303e-07 -120.709154537671 37.575811748064 -3.21241641689591 0.00139696836011351 ZNF239 other 7.50798599553063e-08 1 0.00121400477112711 5.36838334134933 -3.21241641689591 2.84568754047897e-23 30.5721420580665 4.28270469102644 7.13851275389695 3.04016095126581e-12 -82.4118752390537 15.2549086854017 -5.40231848899353 9.85788962769904e-08 ZSCAN16 other 3.58044406343064e-19 0.00130508600781108 3.6564015760874e-08 7.13851275389695 -5.40231848899353 3.65806745874643e-08 31.6170339546839 13.8978641333756 2.274956327912 0.0232975597693842 -137.244090306296 30.940533838894 -4.43573763209515 1.11126478255513e-05 MVB12B other 0.000273513703890471 0.133807392467463 1 2.274956327912 -4.43573763209515 1.70895869441265e-24 749.052808813395 74.6179369030638 10.0385087004816 7.30032673565931e-22 -253.487716503716 254.689795598578 -0.995280222782239 0.320044117927643 C6orf106 other 2.19191042145367e-20 1 1.02022066130839e-17 10.0385087004816 -0.995280222782239 1.66573840591644e-10 9.85294527045144 2.95064746003344 3.3392485560914 0.000899376144628879 -53.5065612117107 10.8066039500043 -4.95128362797909 9.93586397883471e-07 ZNF709 other 1.42354004169619e-06 0.0126205344259158 1 3.3392485560914 -4.95128362797909 0.144019825910421 16.1588982172424 9.13072493539105 1.76972785091903 0.0773367660933031 -9.62173942576671 25.5611836974282 -0.376419947513416 0.70675257058917 POTEI other 1 1 1 1.76972785091903 -0.376419947513416 0.000426935222543959 19.4015883095744 4.99855300621933 3.88144094609668 0.000116758791961556 41.3346413529827 31.0564056308585 1.33095380850872 0.183769020390319 ADA other 1 1 0.958239405628489 3.88144094609668 1.33095380850872 0.103926290516345 -59.0255494909388 51.5915119683916 -1.14409419764828 0.253112979492727 -386.476636658484 195.940546384235 -1.97241787771996 0.0490933474612631 ARID5A other 1 1 1 -1.14409419764828 -1.97241787771996 2.482639398905e-06 103.570882085068 28.2375591855592 3.66784116872377 0.000268834111254381 -141.887385979679 62.5698360385601 -2.2676643405656 0.023743959651872 PPTC7 other 0.015993163007746 1 1 3.66784116872377 -2.2676643405656 0.251307701330296 -0.0888617053771965 4.54701009817295 -0.0195428871849003 0.984415190143664 -24.2546012885926 14.7876381215466 -1.64019440354386 0.101542814166253 RGPD4 other 1 1 1 -0.0195428871849003 -1.64019440354386 8.72159871100944e-10 68.6757153003392 28.7177170471301 2.39140580665351 0.0171214957982557 -256.596956596285 54.4978618636145 -4.70838575719614 3.16995019364656e-06 NHLRC2 essential 7.15956038186765e-06 0.0393232321521855 1 2.39140580665351 -4.70838575719614 0.265139080377831 4.86406627015566 2.98331572554406 1.63042289775368 0.103605123669933 4.68662465609496 11.7234037111814 0.399766550018662 0.689489223577946 HIST1H2AD other 1 1 1 1.63042289775368 0.399766550018662 6.40834996973947e-07 27.6617146456361 5.72044693895608 4.83558626464317 1.73116518969662e-06 -32.0857610083674 23.0283542766202 -1.39331541555025 0.164094496567388 ZFP28 other 0.00435383296944099 1 0.016416639493893 4.83558626464317 -1.39331541555025 2.16345022921344e-07 -18.502220640458 24.3995497318498 -0.758301724572654 0.448598158530082 -462.493824371951 82.3597013133495 -5.61553547422817 3.12600566384728e-08 KIAA1211L other 0.00152717951680177 0.000420604062070651 1 -0.758301724572654 -5.61553547422817 0.0761961232087568 28.9167441199516 13.3031645481236 2.17367409200619 0.0301625593036018 0.223152835174382 39.0302592836066 0.00571743153313127 0.995440282116051 SCN8A other 1 1 1 2.17367409200619 0.00571743153313127 0.0305879030369224 3.63057757483655 3.57074378669556 1.01675667359947 0.309722008308009 -50.4039039602266 21.223076865063 -2.37495742397279 0.0178973509653099 HIST3H2BB other 1 1 1 1.01675667359947 -2.37495742397279 1.19461956483438e-27 45.241515503941 5.28056121699378 8.56755819028209 1.10669392861613e-16 -68.8679204558079 16.5330655760475 -4.16546587437368 3.61612135146211e-05 KPNA5 other 1.59708689622708e-23 0.420735719242616 1.45740523459459e-12 8.56755819028209 -4.16546587437368 0.735306803530219 3.04622567600407 5.07468078835385 0.600279269386759 0.548582145466112 -7.95280579356388 21.9575580955477 -0.362189901033506 0.717357553536571 ANKRD36B other 1 1 1 0.600279269386759 -0.362189901033506 3.26959001584705e-20 115.530536251064 200.41026493331 0.576470153809281 0.564536312299689 -2794.45998559077 365.447785581337 -7.64667374066991 9.43210721563069e-14 ARHGEF12 other 3.88688861083897e-16 1.40151681117056e-09 1 0.576470153809281 -7.64667374066991 6.31611940928108e-07 129.459569697129 58.2154197641796 2.22380204800629 0.0265731121297086 -525.013792924033 129.122032815441 -4.06602793865904 5.49130724999524e-05 HCAR1 other 0.00429306636248835 0.631719986039453 1 2.22380204800629 -4.06602793865904 5.06974244693545e-34 216.486271559103 16.6138839527889 13.0304432229263 1.99681632600695e-33 -159.965612428582 113.795001949769 -1.40573495924885 0.160452495439195 ZNF252P other 7.18078320183937e-30 1 2.97046396656794e-29 13.0304432229263 -1.40573495924885 0.209629055870234 59.2360678074606 43.6380066669536 1.35744210911263 0.175208851862267 -74.3067618314878 124.279954857073 -0.597898204235299 0.550158982689693 PDLIM7 other 1 1 1 1.35744210911263 -0.597898204235299 3.82690433008551e-07 -175.222296213335 46.3384186721581 -3.7813611520286 0.000173718530788966 -591.108461540168 117.905834048132 -5.01339451361552 7.30370541197571e-07 TMEM26 other 0.0026493658677182 0.00933632662812855 1 -3.7813611520286 -5.01339451361552 0.010872080327402 10.1032968565769 41.0527339407048 0.246105335424671 0.805696697926014 -362.458297717461 125.721918815755 -2.88301595403299 0.00410004220914826 SRGAP1 other 1 1 1 0.246105335424671 -2.88301595403299 8.6729178204709e-14 122.22720531652 22.5143390079876 5.42886048189806 8.5512220853729e-08 -278.213602512983 71.8592867855726 -3.87164436161425 0.000121216429230866 FAM3C other 8.55236426276636e-10 1 0.000877269873738406 5.42886048189806 -3.87164436161425 7.58685014348207e-20 239.197706867281 34.4283878125765 6.94768829053051 1.08484315924055e-11 -415.888723631874 94.7823503366542 -4.38782876932988 1.38010195293294e-05 NOP9 essential 8.95703527939493e-16 0.165294810902779 1.28597308096374e-07 6.94768829053051 -4.38782876932988 0.0130404198414891 46.5555355873697 40.6770264935555 1.14451668670387 0.252916464731775 -241.290250256976 102.496327269245 -2.35413557427416 0.0189230733156533 SLC39A10 other 1 1 1 1.14451668670387 -2.35413557427416 3.15860991274793e-09 3.0911003686366 0.727355166053431 4.24978128004322 2.52003129960255e-05 -4.59096982015765 1.61290939236587 -2.8463904059877 0.00458959234284122 SCOC-AS1 other 2.5174121004601e-05 1 0.219872730890322 4.24978128004322 -2.8463904059877 1.3907764519276e-17 32.8911065710653 29.7552839896219 1.10538708293079 0.269483233465585 -399.110551169853 58.2219736017678 -6.85498148688203 1.95070169455319e-11 CASP4 other 1.55238467564158e-13 2.82032450998501e-07 1 1.10538708293079 -6.85498148688203 7.64733044184799e-18 396.456316970273 50.7175181528866 7.81695026509708 2.84251166326092e-14 -447.761948141242 167.320576975382 -2.67607222157214 0.00767486755629671 AP2A1 other 8.60171728099062e-14 1 3.58412295620569e-10 7.81695026509708 -2.67607222157214 4.0106154876026e-21 47.6153305338643 5.42785093004828 8.77240940245218 2.25120055769049e-17 -75.3448179920426 25.0414510844249 -3.00880399214984 0.00274424040383266 ZNF585A other 4.85725641703551e-17 1 2.9981489027322e-13 8.77240940245218 -3.00880399214984 4.45172066228494e-10 46.6105119614454 10.9601100841059 4.25274122283124 2.49707934690121e-05 -101.226632828744 28.2529927625842 -3.58286407671473 0.00037123615422957 FUT11 other 3.71807709714038e-06 1 0.217920114604069 4.25274122283124 -3.58286407671473 2.94331430156664e-08 230.090251769931 47.0876532639032 4.88642427093124 1.3521653265935e-06 -424.272068120111 159.274487040895 -2.66377921538166 0.0079554889043822 ANXA4 other 0.00022148440119289 1 0.0129118267036413 4.88642427093124 -2.66377921538166 8.92356024721463e-14 51.9233971339096 8.28269159060012 6.26890384193909 7.3997699276793e-10 -101.413194896633 27.1652124645042 -3.7332008733282 0.000208934217838666 WDR5B other 8.79238391158058e-10 1 8.2788625950876e-06 6.26890384193909 -3.7332008733282 4.38160844736573e-24 311.336766160795 30.4544236571816 10.2230391770155 1.48243337426882e-22 -173.12786054315 164.460951839784 -1.05269888448542 0.29294723739156 METTL9 other 5.58392180532289e-20 1 2.08459781089681e-18 10.2230391770155 -1.05269888448542 1.31398053564038e-09 34.5094432952604 10.1895331035176 3.38675412746311 0.000761101818161685 -195.800499192351 41.4729372187864 -4.72116306012822 3.02401720476758e-06 ZNF138 other 1.06905456379701e-05 0.0375522456488039 1 3.38675412746311 -4.72116306012822 1.73135458486591e-07 11.3189727745491 7.13183097973288 1.58710614521224 0.113069647427557 -109.476035074275 23.5764389138709 -4.64345083980713 4.30067728727594e-06 ZNF429 other 0.00123133938075663 0.0530230502748251 1 1.58710614521224 -4.64345083980713 9.15985557849798e-05 22.2916381404526 5.62393207724058 3.96371041369157 8.36576456844249e-05 -21.4752779126076 22.6434170917026 -0.948411532836929 0.343341880806271 ZNF470 other 0.50031131169756 1 0.696533557968521 3.96371041369157 -0.948411532836929 2.14559063065833e-09 42.7669734322723 13.9715418372186 3.06100600281252 0.00231485041200334 -232.93803106533 52.214675520899 -4.46116017655028 9.91027663927686e-06 SERTAD1 other 1.72827325299529e-05 0.119686410972547 1 3.06100600281252 -4.46116017655028 7.40314574141322e-09 59.8922751368547 11.3195675477708 5.29103915711424 1.76374565604525e-07 -63.3535149403897 40.2739622355055 -1.57306387114147 0.116283285054839 ZNF100 other 5.77667462202473e-05 1 0.00177521000280955 5.29103915711424 -1.57306387114147 1.07896287538464e-19 58.9098664598531 11.8371273347113 4.97670294439642 8.71949568580133e-07 -233.22986839873 36.8155408216681 -6.33509282203619 5.01542328372345e-10 ZNF398 other 1.27026299319034e-15 7.07174683005006e-06 0.00842128893334692 4.97670294439642 -6.33509282203619 1.03567290866684e-15 27.5074783247552 7.80243301138183 3.52550009524319 0.000458801261129831 -162.836211538702 24.8118596556552 -6.56283784442525 1.24541316726812e-10 ZSCAN25 other 1.09491339904258e-11 1.77745367232506e-06 1 3.52550009524319 -6.56283784442525 1.97855459342582e-11 373.170741426513 218.346359218381 1.70907700390499 0.0880028664921359 -3039.01917423354 510.511611843269 -5.95288942255548 4.70666794830724e-09 ANXA6 other 1.76754511339356e-07 6.49378976827949e-05 1 1.70907700390499 -5.95288942255548 1.51443085884437e-09 20.6324274089138 5.6885324694146 3.62702112009515 0.000314588421920564 -89.1695316267299 20.8751247535282 -4.27156880160243 2.30317815832277e-05 ZNF441 other 1.22820342652278e-05 0.271636831992588 1 3.62702112009515 -4.27156880160243 1.68070497294171e-13 173.070809680049 49.3753941320559 3.50520360844445 0.000494169307548713 -609.084728776889 111.162172297876 -5.47924456841987 6.56055686404973e-08 GMFB other 1.63969577160194e-09 0.000873210118605019 1 3.50520360844445 -5.47924456841987 0.0500707883130476 -36.4312419567092 28.6791729328131 -1.27030308865799 0.204522726873831 -149.459764797236 61.2900273742021 -2.43856580263408 0.0150662852572207 SIGLEC15 other 1 1 1 -1.27030308865799 -2.43856580263408 1.44392153650661e-15 39.7890332182215 6.22987085934525 6.38681509080322 3.63715444471318e-10 -118.419727436448 28.7415790148074 -4.12015385012211 4.37609448694122e-05 ZNF420 other 1.51842788779035e-11 0.506795502532662 4.11980483952662e-06 6.38681509080322 -4.12015385012211 1.81057238968536e-19 20.9487875749816 3.15306270641776 6.64394892380108 7.65460924132793e-11 -57.366406973571 11.3081590654785 -5.0730102611219 5.4412472837392e-07 ZNF763 other 2.12072344003846e-15 0.00699200275960487 8.84566643927856e-07 6.64394892380108 -5.0730102611219 8.57065706619672e-10 59.8080187143713 12.6769710488087 4.7178477006928 3.04081675678475e-06 -51.5987755686337 23.2937292322068 -2.21513588718509 0.0271680273854938 ZMYM1 other 7.03822358276075e-06 1 0.0283981876916127 4.7178477006928 -2.21513588718509 1.98146428328678e-13 28.6759130197843 7.88505376085778 3.63674286688247 0.000302412501311558 -151.72133535977 27.6191439005958 -5.49333954397105 6.06923324253329e-08 ZSCAN26 other 1.92756845478138e-09 0.000809150175894539 1 3.63674286688247 -5.49333954397105 2.17519481112162e-14 132.842485002659 16.2603500646066 8.16971863919543 2.28957390596148e-15 80.5433674802237 45.7596722477787 1.76013864443999 0.0789621845585346 MAFG other 2.19259636961059e-10 1 2.94599474480063e-11 8.16971863919543 1.76013864443999 4.71533781376885e-10 127.566595548881 58.6342461598564 2.17563290915503 0.0300550920878814 -725.888917005027 136.687824920773 -5.31056015724713 1.65400077589282e-07 ARRDC1 other 3.93447787180873e-06 0.00216740261672995 1 2.17563290915503 -5.31056015724713 2.6502940890575e-28 696.242800583408 91.0812755892854 7.64419246523281 9.57274533105806e-14 -862.969858647492 200.514831553356 -4.30377070844189 1.99150107564778e-05 KIAA1671 other 3.5675608732803e-24 0.236072537507288 1.19228543098328e-09 7.64419246523281 -4.30377070844189 4.31279677706958e-18 921.82277182304 123.18306868959 7.48335612701736 2.91089176682848e-13 -352.087663706836 258.070636212482 -1.36430734187421 0.173031892234183 IGF2R other 4.87734187518799e-14 1 3.58738301343942e-09 7.48335612701736 -1.36430734187421 0.842995680360174 -1.96616970775746 16.4337619584528 -0.119642094897581 0.904811252043926 27.0209331062948 52.4693355821287 0.514985234833015 0.606774459312517 GAL3ST4 other 1 1 1 -0.119642094897581 0.514985234833015 5.82275799629226e-12 1940.74559688025 288.171538581101 6.73468867340645 4.22861672648486e-11 -130.705035180562 602.398579418098 -0.216974341650705 0.828310595134844 DYNC1H1 essential 5.34063363419927e-08 1 4.92084128461043e-07 6.73468867340645 -0.216974341650705 0.00328027852173869 56.051700125151 17.4543700537358 3.21132759031622 0.00139929536617414 12.970967155526 37.8611875943696 0.342592717758673 0.73203721178396 SLC6A17 other 1 1 1 3.21132759031622 0.342592717758673 4.63126721046317e-19 588.083465231709 172.919976679361 3.4008995173656 0.000721536815804587 -4138.18069817082 538.041011902518 -7.69119938188015 6.989785305326e-14 PCBP2 essential 5.36439680987948e-15 1.03966066631419e-09 1 3.4008995173656 -7.69119938188015 1.79105871842488e-35 185.883414150319 13.7717872162104 13.497406780401 1.02328792170584e-35 -87.4853041657481 107.111941403484 -0.816765180608541 0.414443987636075 ZGPAT other 2.56407966129705e-31 1 1.53175969000148e-31 13.497406780401 -0.816765180608541 1.95501915685822e-08 59.7359443746159 94.2316619926629 0.6339264649632 0.526395756959902 -1032.58677206747 193.690337413454 -5.33112175783605 1.43381826570072e-07 SLC25A29 other 0.000148718307262205 0.00188547101939645 1 0.6339264649632 -5.33112175783605 0.0678688626888294 30.4342007092136 17.5515796465267 1.7339864172987 0.0834922709141339 -48.5562405775193 44.576367955796 -1.08928211974717 0.276516265006448 PGAP1 other 1 1 1 1.7339864172987 -1.08928211974717 2.08721851713778e-17 252.120561425079 27.7643484447175 9.08073034478315 2.1148124582059e-18 147.639719731873 187.888823468073 0.785782341954794 0.432345499991984 SRC other 2.31743871957808e-13 1 2.85626570605289e-14 9.08073034478315 0.785782341954794 0.000222275294677651 15.2764965418036 5.08283825173662 3.00550514991977 0.00277529855209118 -30.1019315053313 17.3059637570097 -1.73939642587883 0.0825380525305228 ZNF682 other 1 1 1 3.00550514991977 -1.73939642587883 3.75146278144523e-18 84.5274732519495 9.15521556009885 9.23271251201832 5.82295167860191e-19 18.8208069579154 45.622802287297 0.412530708644256 0.680112704514923 ZNF772 other 4.25078247765559e-14 1 7.91572051189143e-15 9.23271251201832 0.412530708644256 5.01416455176013e-05 16.0554586234231 3.8231248555445 4.19956429101149 3.12267647857792e-05 -3.89668797731515 14.7783770499553 -0.263674959986689 0.792129874042607 ZNF257 other 0.283350438819965 1 0.270517463339205 4.19956429101149 -0.263674959986689 4.8911269244013e-16 229.843509745604 47.0155638742127 4.8886685770809 1.35119895070942e-06 -636.248839292862 122.433781968488 -5.19667716755346 2.90950833831349e-07 PCNX3 other 5.21834331564375e-12 0.00377595992146324 0.012903949979275 4.8886685770809 -5.19667716755346 4.64763158166494e-50 13.5440171982993 0.824916364573939 16.4186550054619 7.52301973432051e-48 -24.1718852053286 10.1403446578775 -2.38373408605503 0.017549878418038 ADAM32 other 7.02954276726822e-46 1 1.15004402678558e-43 16.4186550054619 -2.38373408605503 0.793536875464755 -12.9895209007427 39.7763783593325 -0.326563690223322 0.744123279996227 -50.2794779938243 74.1960241616967 -0.677657307947516 0.498276574270107 ACSL5 other 1 1 1 -0.326563690223322 -0.677657307947516 3.89646944765293e-12 245.481758640508 38.3919785100703 6.39408981165474 3.51790122050448e-10 -72.7576913505964 76.4823234105596 -0.951300746448703 0.341880487788804 LRRC8B other 3.59644130018365e-08 1 3.98683745319772e-06 6.39408981165474 -0.951300746448703 2.55764891265407e-21 114.23694175706 22.9411257382401 4.97957001153787 8.56940636901393e-07 -479.909562549736 71.377540243573 -6.72353741684099 4.49389316131948e-11 ABCB8 other 3.10831072354849e-17 6.45997141939676e-07 0.00828147431501507 4.97957001153787 -6.72353741684099 4.46106412985244e-05 6.6174645411436 1.63060845423911 4.05827930300504 5.68109418793502e-05 18.8807057245629 6.095640468692 3.09741130920314 0.00205462983781702 HIST1H3J other 0.254236044760291 1 0.480336513589906 4.05827930300504 3.09741130920314 4.10885424234981e-12 372.304109269216 96.5558780600793 3.85584095706281 0.000129124109966617 -1690.94730331141 344.653099439171 -4.90622978891809 1.2284166066001e-06 SND1 other 3.79000715314347e-08 0.0155357848236715 1 3.85584095706281 -4.90622978891809 1.04358740914178e-18 69.2920156154841 9.31218716139224 7.44100332334004 4.06994499768919e-13 -214.936385089089 55.8580407729632 -3.84790411755945 0.000133679994245327 ZNF785 other 1.1983514219175e-14 1 4.99097355066625e-09 7.44100332334004 -3.84790411755945 4.33778220045576e-08 31.6553051167938 6.38430435762739 4.95830138157102 9.57808571243692e-07 -74.8036714576582 38.4184401806864 -1.94707726565284 0.0520513038275729 SULT1A2 other 0.000321993572739831 1 0.009224654349648 4.95830138157102 -1.94707726565284 1.59057577592772e-21 -22.8148301076419 11.3834121343692 -2.00421717480988 0.045553191250227 -190.233297136397 19.821284151589 -9.59742545848857 3.18128984698696e-20 NEK5 other 1.94050244663182e-17 4.90300391217631e-16 1 -2.00421717480988 -9.59742545848857 6.43706433487256e-84 638.850009636583 26.8808136605123 23.7660220298706 3.62011685022601e-85 402.875457533757 116.352040304665 3.46255601946332 0.000578985701391341 PSMD12 essential 1.00231528758301e-79 1 5.64267613444729e-81 23.7660220298706 3.46255601946332 0.634285051427403 9.7512091074421 10.3669990226401 0.940600947887312 0.347331522231857 9.72765481655335 20.9492738890204 0.46434329266427 0.64258965286148 PIWIL2 other 1 1 1 0.940600947887312 0.46434329266427 1.62549672902734e-08 83.0894100641695 19.1507616103414 4.33870003474437 1.71161076727673e-05 -404.294104125946 111.331619162199 -3.63144008115908 0.00030874814499965 NOL4L other 0.000124155440163109 1 0.151237927396572 4.33870003474437 -3.63144008115908 0.1535729478516 4.17505877562908 4.99209628662996 0.83633378362731 0.403362706302357 -16.2219672411576 11.6337854551485 -1.39438425297577 0.163814719490583 CYSRT1 other 1 1 1 0.83633378362731 -1.39438425297577 5.10368738873149e-08 10.8286060589335 8.36745836901396 1.29413324588905 0.196167508304068 -93.7354673726251 19.6032022796492 -4.78164057256785 2.24038557138603e-06 SLC22A4 other 0.00037787701426168 0.0279980984856112 1 1.29413324588905 -4.78164057256785 1.11831884126791e-48 110.597578689022 35.5317135792505 3.11264410151071 0.0019514517183669 -746.467317613828 72.0214638529989 -10.3645118785342 4.2670014141949e-23 ENTPD4 other 1.68530649379074e-44 6.62409299539616e-19 1 3.11264410151071 -10.3645118785342 1.01952853880124e-05 28.6150584532553 6.55209147953494 4.36731668698959 1.50534713572941e-05 -27.4640366955082 21.3705660465744 -1.28513379737597 0.199290405002003 C1D essential 0.0619669445883394 1 0.1336296652387 4.36731668698959 -1.28513379737597 1.17028539197103e-33 683.296129149505 79.9458623523294 8.5469855355134 1.33177779158276e-16 -1445.85822652346 214.440385543287 -6.74247167976479 4.05208476670912e-11 TBC1D9B other 1.65291108761989e-29 5.83013956234109e-07 1.75128779593132e-12 8.5469855355134 -6.74247167976479 0.496141304410021 2.4745057437913 2.89586391226683 0.854496557420857 0.393217448413686 -6.04767808390816 11.1052655968037 -0.544577527767438 0.586274029761619 HIST1H4J other 1 1 1 0.854496557420857 -0.544577527767438 0.146866748302181 -9.30688675027482 7.27678578371596 -1.27898319765051 0.201447274963213 -23.3707465677203 12.0872347834036 -1.93350646252107 0.0536913617062202 FAM110D other 1 1 1 -1.27898319765051 -1.93350646252107 0.0869228956201598 -1451.94794230892 1626.37534790425 -0.892750830354076 0.372383197618165 -7471.40701599685 3372.71440702188 -2.2152504227579 0.0271540065373422 SERPINA1 other 1 1 1 -0.892750830354076 -2.2152504227579 0.43242613492067 9.98329003996619 229.670863768072 0.043467812486862 0.965344690211224 -1261.72255737294 1045.57014345563 -1.20673162414806 0.228063881429539 TPSB2 other 1 1 1 0.043467812486862 -1.20673162414806 1.49925353734174e-05 113.453030804762 51.5526057726153 2.20072349601829 0.0281765831661102 -610.624132431547 174.509788417257 -3.49908241806776 0.000505248610467476 KANK2 other 0.0898202794221435 1 1 2.20072349601829 -3.49908241806776 9.66733474536465e-15 198.919697571471 24.3545699101941 8.16765388610736 2.22359295407754e-15 83.0969680521827 121.732287420455 0.682620608000005 0.495138251866655 C6orf141 other 9.88098284323721e-11 1 2.86176413189779e-11 8.16765388610736 0.682620608000005 2.12852564341706e-43 171.507893763257 17.2118487829651 9.96452478324129 1.43981275234237e-21 -119.585559603956 36.1439194439409 -3.30859412713756 0.00100073741738344 GTF2E2 other 3.16107343303868e-39 1 2.00810684569191e-17 9.96452478324129 -3.30859412713756 2.45178358622021e-44 54.2659559831224 3.48953728225257 15.5510463404743 2.98131679583304e-45 90.4815807092345 40.4734147531703 2.23558059681997 0.0257917563984523 RAD54B other 3.65217683003362e-40 1 4.54293053349038e-41 15.5510463404743 2.23558059681997 9.14366435144292e-08 27.3072983037304 5.79767148821365 4.71004581050249 3.15065117834982e-06 -35.8477340790659 20.6870952054276 -1.7328548896348 0.0836902624880175 ZNF165 other 0.000662549918905554 1 0.0293798222381121 4.71004581050249 -1.7328548896348 7.70858624626107e-15 13.0530074206841 9.73432315496411 1.3409260420975 0.180512434880819 -152.731899906455 21.7348544528994 -7.02704958238547 6.43674295388292e-12 RAMP2-AS1 other 7.91286378178699e-11 9.37125406655814e-08 1 1.3409260420975 -7.02704958238547 2.27680232646253e-20 143.480650348087 15.9121619971735 9.01704308776981 3.45348380435971e-18 -282.2539653783 96.8167292426841 -2.91534291218197 0.00370215792558695 FITM2 other 2.71485909407392e-16 1 4.65322407799428e-14 9.01704308776981 -2.91534291218197 5.19195978898706e-21 90.2096882860214 10.1742027986982 8.86651171309105 1.08899147609165e-17 209.856494789794 31.3541727829661 6.69309620261466 5.46593620669969e-11 BLM ts 6.27552179694866e-17 7.84635142471741e-07 1.45761509074868e-13 8.86651171309105 6.69309620261466 0.00230777370130383 -99.5067606313949 35.8779134968107 -2.7734823721073 0.00573668865528301 -390.422493029262 154.146109503864 -2.53280795918807 0.0115957519043324 GATA3-AS1 other 1 1 1 -2.7734823721073 -2.53280795918807 4.9059385329487e-18 452.315096310097 89.242251831281 5.06839627002277 5.50694041911428e-07 -568.527620442836 144.261315438429 -3.94095685815012 9.17392979898513e-05 DDI2 other 5.53929519755238e-14 1 0.00538506642664045 5.06839627002277 -3.94095685815012 0.0881514732124093 238.389241534945 149.682589078183 1.592631734947 0.111822618979463 -597.236096647027 543.93883300415 -1.09798392835554 0.272696353654873 SVIL other 1 1 1 1.592631734947 -1.09798392835554 1.35192416765712e-14 307.173889290089 46.839159509355 6.55805724329314 1.27714447400581e-10 -215.629884768752 109.629866203099 -1.96688997475631 0.0497074909147326 TRIM33 other 1.37396053158993e-10 1 1.46705585729047e-06 6.55805724329314 -1.96688997475631 1.2335624020551e-35 923.00378240482 112.494082416343 8.2049096501695 1.70577815907053e-15 -2970.39959606446 367.344441414057 -8.08614276189996 4.08767354417136e-15 LRP10 other 1.76818834710578e-31 6.14213826747188e-11 2.20062440301689e-11 8.2049096501695 -8.08614276189996 1.35526215355827e-05 157.860661362441 33.5677833218422 4.70274309890825 3.25950328742602e-06 -9.94445507112395 118.75502023927 -0.0837392394114171 0.933294619910013 PELI1 other 0.0814783606719231 1 0.0303492351092236 4.70274309890825 -0.0837392394114171 7.51995057255648e-10 62.806868872198 33.9674103556205 1.84903318253125 0.0649993733006034 -600.709420331401 108.061073810553 -5.55898066851096 4.27013789210554e-08 ZNF655 other 6.1971912668438e-06 0.000572155776163221 1 1.84903318253125 -5.55898066851096 1.23951549568329e-91 246.996325163344 9.7683037989116 25.2854876596759 2.34109000776492e-91 -1.01113962831663 74.7929672593869 -0.0135191805508923 0.989218997298549 MRPL21 essential 1.93314836706766e-87 1 3.65303684811638e-87 25.2854876596759 -0.0135191805508923 5.86554849265511e-08 89.3101201172008 18.3185547455206 4.87539117347889 1.45440850912643e-06 -64.1513799313906 42.5418404165499 -1.5079596769498 0.132186474804397 UAP1L1 other 0.000432290923908682 1 0.013850332232411 4.87539117347889 -1.5079596769498 3.02073273952917e-05 10.3291483403063 2.28914931249445 4.51222132340981 7.86063326891763e-06 4.43479212911692 8.8402844004 0.501657178463201 0.616110904613644 ZNF98 other 0.175202498892692 1 0.0713981319815788 4.51222132340981 0.501657178463201 8.2647806941671e-05 14.8701310825174 3.40144782302517 4.37170636040868 1.47929202237933e-05 8.20827340473963 7.53363345052369 1.08955040866357 0.276397214648209 FBXL22 other 0.454480290372249 1 0.131435096188404 4.37170636040868 1.08955040866357 2.25470051822537e-26 34.8489050168751 5.36356656327672 6.49733803165204 1.8620438900218e-10 -115.166461796128 16.7081131422392 -6.89284665573517 1.53351913484189e-11 ZNF786 other 2.96853870229552e-22 2.22084241107803e-07 2.1270127355719e-06 6.49733803165204 -6.89284665573517 7.04451428213252e-22 64.9706582266291 6.69712765882172 9.70127217763981 1.93866973004309e-20 -104.442690120815 45.438287775116 -2.29856130666112 0.0219587203780907 ZNF517 other 8.66263921273836e-18 1 2.67730289718951e-16 9.70127217763981 -2.29856130666112 0.000277131311875346 31.9905089100028 9.14707891157399 3.49734699123723 0.000509141257433231 -33.5912816539575 35.0988204037459 -0.957048734617091 0.338976545080153 ZNF675 other 1 1 1 3.49734699123723 -0.957048734617091 1.72585495920324e-28 124.661832789734 32.3384418489682 3.85491154372706 0.00012957608757255 -679.111834342106 75.7621955218285 -8.96372959712395 4.99651793238964e-18 SLC22A5 other 2.32748799798149e-24 7.64117487400348e-14 1 3.85491154372706 -8.96372959712395 0.00213034133654348 -14.228112270789 6.97552050449269 -2.03972051427921 0.0418589739113686 -69.3722363006532 20.3604266660763 -3.40720935952871 0.000704671415519205 DACT3 other 1 1 1 -2.03972051427921 -3.40720935952871 0.00253961441249562 64.7903170280473 18.7115618707121 3.46258198410786 0.00057727197767963 58.3640308316741 53.5745875922003 1.08939766883378 0.276462681976397 ADARB1 other 1 1 1 3.46258198410786 1.08939766883378 4.87544327009266e-06 -4.88647217004304 7.95168749689977 -0.614520147069185 0.539128120122671 -78.7423776261477 16.2347547910214 -4.85023510608832 1.6114684704843e-06 ZNF860 other 0.0304763958813492 0.020267438953281 1 -0.614520147069185 -4.85023510608832 3.09688241061481e-20 534.767514435571 113.078064038379 4.72918880406432 2.87213742286843e-06 -1125.0305662204 219.307950416786 -5.1299123633335 4.03153132538476e-07 HTT other 3.68374162742631e-16 0.00520309432854157 0.0268745898657799 4.72918880406432 -5.1299123633335 0.799001102487178 8.65422685483182 14.709426105187 0.588345649445837 0.556542707226907 21.1029556055653 42.4228374486317 0.497443284672275 0.61907601941171 C5AR1 other 1 1 1 0.588345649445837 0.497443284672275 0.480724996923243 1.79862350511881 20.3673520182102 0.0883091480674897 0.92966358689662 -45.8158773745983 42.2384509017997 -1.08469596768868 0.278538573644866 DIO3 other 1 1 1 0.0883091480674897 -1.08469596768868 0.0530659323341718 -1.36434841901966 11.2915169571546 -0.120829506274192 0.903870529970828 -90.6255797540681 38.6945240606971 -2.34207764416253 0.0195351411208696 CYP2B6 other 1 1 1 -0.120829506274192 -2.34207764416253 0.334716909404865 5.4393452721432 3.6799965181065 1.47808435290095 0.13997809556577 4.68686629724781 14.4574474530981 0.324183526341882 0.745926750016184 HIST1H3D other 1 1 1 1.47808435290095 0.324183526341882 0.000164437422279645 30.2165551947213 11.4452641471008 2.6400924265584 0.00852628544323196 104.152998612897 25.8411280539446 4.03051284740639 6.35928683162403e-05 DCHS2 other 0.868394027058806 0.727756785011054 1 2.6400924265584 4.03051284740639 0.143978744205874 18.509399043271 9.39451286442235 1.97023510536318 0.0493228648140423 6.22340543012526 36.4299905882518 0.170831925280053 0.86442003342351 VEPH1 other 1 1 1 1.97023510536318 0.170831925280053 3.69413184907214e-34 40.1565612509312 14.6179946944664 2.74706360826171 0.00621099947801506 -292.227023352301 27.0132269489036 -10.817923527058 7.47880365420823e-25 SHPK other 5.2382789619843e-30 1.16422536485059e-20 1 2.74706360826171 -10.817923527058 0.0170897911600822 3.81275699864159 3.90617531530894 0.976084453685111 0.329462109551935 -13.551552113905 7.69506535851537 -1.76107043703129 0.0787955793390337 GGT3P other 1 1 1 0.976084453685111 -1.76107043703129 1.76789820296086e-06 49.7463554136641 14.380877746528 3.45920160719497 0.000584165941591625 -70.0395305075534 29.768266593512 -2.35282529090285 0.0189858903746092 IPP other 0.0115461431635374 1 1 3.45920160719497 -2.35282529090285 0.000786864229461681 16.6077909868479 24.3177998242279 0.682947927316252 0.494939857052439 -169.720321464227 56.1616726068241 -3.02199549241353 0.00263319669749312 MAP3K5 other 1 1 1 0.682947927316252 -3.02199549241353 0.177635039848503 5.38281139239124 5.27362317595416 1.02070459204119 0.307848117354739 27.1137962105206 15.1292012754901 1.79214987736637 0.073664548725266 OGDHL other 1 1 1 1.02070459204119 1.79214987736637 2.810357281496e-13 152.585220035369 68.7745297651119 2.21862978280621 0.0269223991072175 -1487.7922204158 227.803123899631 -6.53104397756771 1.49677359150189e-10 GSTK1 other 2.71761549120663e-09 2.13230365845359e-06 1 2.21862978280621 -6.53104397756771 1.81575687326956e-16 801.263719351552 96.4072203103507 8.31124180089575 7.65466167916082e-16 41.8299439996807 263.450462735959 0.158777265240958 0.873903504568703 HNRNPAB other 1.96265160431707e-12 1 9.93498539338283e-12 8.31124180089575 0.158777265240958 1.08658096704904e-13 386.80209439413 48.6059478139816 7.9579169173791 1.13708488961914e-14 348.400793323605 348.580176514008 0.999485389008071 0.318032662169053 STMN3 other 1.06734848393227e-09 1 1.44603085412866e-10 7.9579169173791 0.999485389008071 0.000320808612496568 78.3942965457132 19.5276632409903 4.01452521882682 6.83850946302845e-05 41.5052095354479 70.4727205718057 0.588954267675216 0.556149188846492 PDGFA other 1 1 0.573614173758827 4.01452521882682 0.588954267675216 0.241260645319525 7.70131783935024 4.91725183830857 1.56618332609121 0.117886122572006 14.2811358508648 13.0639561784421 1.09317083246431 0.27480175407569 COL13A1 other 1 1 1 1.56618332609121 1.09317083246431 1.97460152412827e-06 20.5346044812066 3.98400536036806 5.1542612581499 3.58208754128772e-07 21.5531075248591 25.539036047835 0.843927996518342 0.399084726472397 ZNF695 other 0.0128526813205509 1 0.00354519203961245 5.1542612581499 0.843927996518342 0.935415551729233 1.71311079113135 7.10355900227193 0.241162323081071 0.80952102112781 5.92385963311247 17.2939321772494 0.342539774783288 0.732078251566263 PCDHB11 other 1 1 1 0.241162323081071 0.342539774783288 2.20169039361629e-09 22.1873311867613 3.82675115183275 5.79795505546136 1.14961995461534e-08 -29.1230073330885 16.6806268963255 -1.74591803498128 0.0814002728627558 ZNF628 other 1.77214059782175e-05 1 0.000122790907352465 5.79795505546136 -1.74591803498128 0.00291908287987109 197.533688652135 72.4684022605307 2.7257905858333 0.00662458541032252 -701.48305898349 427.783409221886 -1.63980894036879 0.101631618034629 SLC2A10 other 1 1 1 2.7257905858333 -1.63980894036879 2.34636071861548e-06 9.47729785049837 2.48312426982696 3.81668286426874 0.000150764400487064 -28.8003018227634 10.5830751646733 -2.72135474563196 0.00670937950621343 ZNF665 other 0.0151598366029746 1 1 3.81668286426874 -2.72135474563196 3.64909622091336e-44 183.730408511329 15.1470260435983 12.1298007927425 4.09989122838678e-30 -152.288167996508 43.0363229854726 -3.53859617718537 0.000436929170558332 RPF2 essential 5.43204463445162e-40 1 6.02971002958844e-26 12.1298007927425 -3.53859617718537 0.359687981540032 30.3612320132081 48.1518996503262 0.630530305838149 0.528614918652515 -108.934005632912 106.295050443541 -1.02482669868784 0.30590467727678 SLC28A3 other 1 1 1 0.630530305838149 -1.02482669868784 0.867893361582718 4.5427192964532 10.5746699671193 0.429584971500599 0.667669562610161 -17.4490540223134 65.4249233533326 -0.266703469075207 0.789799674592388 FAM177B other 1 1 1 0.429584971500599 -0.266703469075207 4.54793950730214e-05 11.4471943258959 23.5980452814404 0.485090785671938 0.627812009213067 -177.502906065544 46.0944289385951 -3.85085378326316 0.000132067115667522 MIB2 other 0.259005154940857 1 1 0.485090785671938 -3.85085378326316 0.00457971825967329 102.372993963015 38.6595635188348 2.6480638849722 0.00833255991000673 -72.1232765082975 84.8357199837576 -0.850152229769559 0.395617932433469 MYO5A other 1 1 1 2.6480638849722 -0.850152229769559 4.60640273859018e-07 8.92879116584276 6.13368827976628 1.45569692468672 0.146052198390371 -61.6761616310841 14.3699468543327 -4.29202433775795 2.09555538490164e-05 C5orf56 other 0.00316505932168532 0.248029935356958 1 1.45569692468672 -4.29202433775795 0.583844138284294 -0.693254262843593 3.60424222963077 -0.192343970986271 0.847547581469001 -6.36340606739261 6.46613936518254 -0.984112112036573 0.325516299535196 GZMM other 1 1 1 -0.192343970986271 -0.984112112036573 1.96522368705905e-19 417.016186052521 43.4084480697933 9.60679786068442 2.67263529345405e-20 123.158308238307 118.147784812397 1.04240894938374 0.297681762508415 ATG7 other 2.29990128096521e-15 1 3.68663312379051e-16 9.60679786068442 1.04240894938374 0.459929669113579 2.12969034880368 6.84234405688944 0.311251572720803 0.75572927609979 18.5719535092363 15.2647208081698 1.21665857781666 0.224264661275648 PRAMENP other 1 1 1 0.311251572720803 1.21665857781666 7.48711004213719e-12 112.444711502808 42.4312747509645 2.65004320899532 0.00828321984302501 -411.474637433535 83.044218682951 -4.95488601084293 9.68857269079335e-07 SIPA1L1 other 6.83049049144176e-08 0.0123151447472674 1 2.65004320899532 -4.95488601084293 3.52067140223471e-08 5.23764914705351 24.8540437265885 0.210736297267005 0.833172841607591 -336.042600251503 59.6279760239443 -5.63565330670559 2.81663009312617e-08 TTC30A other 0.000263416634315201 0.000379569071349683 1 0.210736297267005 -5.63565330670559 2.3916996793569e-06 19.8012524732161 8.53539312984004 2.31989929133905 0.0207210402675907 -93.8350338804538 26.3636624674775 -3.55925638162792 0.000404938879765266 SSPO other 0.0154360297305694 1 1 2.31989929133905 -3.55925638162792 1.33584340640013e-25 210.60360973406 22.575570514333 9.32882779641606 2.85288431966423e-19 -280.920126293597 99.353372924539 -2.82748454354904 0.00486789893898708 RAB40C other 1.73993603683617e-21 1 3.891334212022e-15 9.32882779641606 -2.82748454354904 2.3853423397668e-27 281.200246676554 32.762986549569 8.5828636608299 9.76581842719475e-17 -273.382613959554 73.0706916028922 -3.7413442785689 0.000202516725422998 PIGN other 3.17799159927131e-23 1 1.2877208178099e-12 8.5828636608299 -3.7413442785689 1.88585160423579e-37 11.8811805157019 2.23187978633382 5.32339626374698 1.49807316893314e-07 -77.5536678455525 7.17751635651615 -10.8050840978084 9.18914393813423e-25 ZNF624 other 2.72920444165003e-33 1.43029025397059e-20 0.00151305390062247 5.32339626374698 -10.8050840978084 1.15497347120873e-13 47.3275533919706 9.1330912739217 5.18198624896128 3.10819140724568e-07 -67.6054503559803 17.8416309040392 -3.78919677912824 0.000168170592044755 HHLA3 other 1.13372195933849e-09 1 0.00308798816309858 5.18198624896128 -3.78919677912824 0.600445064464773 -2.82331848297589 2.94102603260735 -0.959977386012081 0.337509335648621 1.76300006981752 12.3067047034008 0.143255250882093 0.886143666490564 HOXA4 other 1 1 1 -0.959977386012081 0.143255250882093 2.16976343482375e-32 115.238233921763 15.6186864523391 7.37822826992631 6.11704918040562e-13 -266.397061639453 37.1937045494436 -7.16242344951998 2.61976709684329e-12 TOPORS other 3.03419718725753e-28 3.83350519281079e-08 7.47014045911134e-09 7.37822826992631 -7.16242344951998 0.000182072383012941 0.0808407491829482 3.20301588788603 0.0252389472961068 0.979873609714899 -20.2862859108056 5.89626185150879 -3.44053341281214 0.000625057757819382 BCO2 other 0.955697938434926 1 1 0.0252389472961068 -3.44053341281214 9.23761586101957e-21 415.558086693079 52.7797195724667 7.87344249001772 1.93150095712094e-14 -880.353720966358 224.914332356845 -3.91417350660252 0.000102428473086806 ENTPD6 other 1.11137756423926e-16 1 2.44238296027943e-10 7.87344249001772 -3.91417350660252 7.1595305288581e-08 16.2335969028384 2.92112335655721 5.55731303383609 4.29165921910161e-08 22.0315832640692 6.0044524635812 3.66920770839595 0.00026720797258918 DMBX1 other 0.000523433276964816 1 0.000446933391077241 5.55731303383609 3.66920770839595 0.000125398659324034 235.285034296134 125.154409546028 1.87995800667018 0.0606549128184256 -751.370716350534 296.776982205196 -2.53176884126083 0.0116329117658028 ENPP1 other 0.674143192526009 1 1 1.87995800667018 -2.53176884126083 2.65322535186573e-09 19.5788009189232 3.42792952624982 5.71155292691871 1.8473394828325e-08 -13.0864809266416 15.5476518120664 -0.841701440502109 0.400326308678649 CCDC154 other 2.12337624909814e-05 1 0.000195596304442305 5.71155292691871 -0.841701440502109 8.83946391254641e-12 333.414559058841 72.8450101235522 4.57704046568649 5.86915153448588e-06 -557.235588048483 165.606578333245 -3.36481553846958 0.000820888573166426 FAR1 other 8.03595664289595e-08 1 0.053802512116632 4.57704046568649 -3.36481553846958 4.86422444910743e-05 75.1695622776481 22.8471190905944 3.2901111943078 0.00106718534490403 -300.930357786047 117.426259826812 -2.56271772795863 0.0106571052118606 C5orf42 other 0.275558315041936 1 1 3.2901111943078 -2.56271772795863 6.67616460004886e-10 54.4372678237265 8.64680650690918 6.29565005071279 6.32687260822586e-10 -32.4012171494604 36.2877016395372 -0.892898025653896 0.372308050318632 ZNF841 other 5.51451195964036e-06 1 7.09685300464695e-06 6.29565005071279 -0.892898025653896 0.781908163642951 -10.6709916728867 74.7917363760434 -0.142676078801465 0.886598547887613 -186.455040851438 265.913146989797 -0.701187748564355 0.483484038181546 MFAP5 other 1 1 1 -0.142676078801465 -0.701187748564355 0.853234830944059 12.8997103423816 42.4559413622719 0.303837576755389 0.761369546994867 -51.4995635149626 139.538879724479 -0.36906963576495 0.712221565243998 MYH6 other 1 1 1 0.303837576755389 -0.36906963576495 2.81268212227145e-11 68.6185586203586 9.85549045511168 6.96247020205561 9.724676920399e-12 -14.841638351199 41.7718027466457 -0.35530279699003 0.722501240764337 ZNF615 other 2.49428650603032e-07 1 1.15441639722057e-07 6.96247020205561 -0.35530279699003 1.01135547965433e-25 564.332949135522 50.315500195799 11.2158866937517 2.42179329660619e-26 626.875034029722 619.875346145895 1.01129208949404 0.312338105985604 CDC42SE1 other 1.319515494305e-21 1 3.49610080298069e-22 11.2158866937517 1.01129208949404 0.812215524292607 -17.5457291390868 38.0458747329763 -0.461172972424236 0.644860202932716 19.3930810495677 94.6432869298776 0.204907095671099 0.837721923227807 MPEG1 other 1 1 1 -0.461172972424236 0.204907095671099 0.948058254972267 -6.98715852987314 21.3927894166765 -0.326612784980082 0.74408662455536 -6.45429530947295 46.7233532276753 -0.138138529527669 0.890182146010516 SERPINB2 other 1 1 1 -0.326612784980082 -0.138138529527669 0.682264536900467 15.746477165266 27.8056411893264 0.566305127008204 0.571419062580852 55.2709805085244 68.4067638863403 0.807975372148267 0.419456631512853 DPP4 other 1 1 1 0.566305127008204 0.807975372148267 7.87056738988916e-09 26.1840315599042 4.37157357628936 5.98961245944064 3.8259687354791e-09 39.9082825804862 10.7563448233446 3.71020855466375 0.0002283767723215 PDCD1LG2 other 6.13038493998466e-05 1 4.15959320921288e-05 5.98961245944064 3.71020855466375 5.59906009132656e-27 34.8172804389034 3.54296580826924 9.82715677290488 4.95138991204431e-21 -44.7641960387316 12.7704546383239 -3.50529384477787 0.000495193251337146 ZNF433 other 7.42659330513555e-23 1 6.87450975388232e-17 9.82715677290488 -3.50529384477787 6.64692700067635e-05 14.8995035086408 5.90090809526207 2.52495095129576 0.0118550910199482 -36.9240175685269 13.3876585065771 -2.75806389522013 0.00601040152055421 DNAH10 other 0.369967956857645 1 1 2.52495095129576 -2.75806389522013 2.90713631420501e-08 376.438031422367 224.652511776833 1.67564577152966 0.0943832762761562 -2475.68380295957 510.312746480396 -4.85130700738764 1.60468052952129e-06 SPTAN1 other 0.000218820150370211 0.0201852763808483 1 1.67564577152966 -4.85130700738764 1.55174184897746e-08 51.4394637375487 10.4521170549002 4.92143969182135 1.14453893931177e-06 130.240191840514 27.405511243017 4.75233578697422 2.58518308111582e-06 NMB other 0.000118584112098858 0.0322243071061087 0.0109761284279999 4.92143969182135 4.75233578697422 4.64773791860063e-05 46.5793957147527 74.8306779439659 0.622463901097247 0.533901092061914 -633.970901854631 164.220989483848 -3.86047425391371 0.00012694857017536 PARVA other 0.264363332810004 1 1 0.622463901097247 -3.86047425391371 0.40629328404832 5.82978378114123 5.01334892395123 1.16285219113505 0.245403097562386 -3.44625803390441 13.1243599928308 -0.262584844959063 0.792970728584076 KLHL14 other 1 1 1 1.16285219113505 -0.262584844959063 2.03000271408547e-12 -5.15102776633935 72.3412236754713 -0.0712045982170179 0.9432608997165 -934.210010699692 143.189683186546 -6.52428296445502 1.55627962556326e-10 FAM114A1 other 1.89419553251315e-08 2.21598655883953e-06 1 -0.0712045982170179 -6.52428296445502 1.27897989427587e-14 173.147517233909 23.3634327270584 7.4110478223253 4.83141576181841e-13 -74.971467637282 54.2602056691816 -1.38170260714408 0.167631232620965 RPE essential 1.30085045046799e-10 1 5.91558545877047e-09 7.4110478223253 -1.38170260714408 0.0249022512368192 10.0612643392669 3.7541648420725 2.68002731966149 0.00758389956677051 -1.84149822506709 18.6784561869046 -0.098589423378478 0.921500451287459 ZNF460 other 1 1 1 2.68002731966149 -0.098589423378478 4.11823304011071e-22 118.891288218553 37.6318958505548 3.15932231239952 0.00166956234336554 -671.6969391936 81.4949116290782 -8.24219482868833 1.28051877145392e-15 PHF2 other 5.08519415792871e-18 1.93217477424682e-11 1 3.15932231239952 -8.24219482868833 1.26299025728858e-07 4276.52730968307 946.225287006046 4.51956565567428 7.61355429593936e-06 -4585.38636001891 2423.07905308938 -1.89238000888689 0.058973000992555 PSAP other 0.000907711097913306 1 0.0691919814414969 4.51956565567428 -1.89238000888689 2.22756924802002e-07 552.103786436395 98.3577105128174 5.61322323951865 3.16056651316742e-08 -418.694066864911 1339.13952333074 -0.312659031841227 0.754658885101959 S100A10 other 0.00157088183370372 1 0.000331290581910209 5.61322323951865 -0.312659031841227 1.86978418449212e-12 15.9729867005341 6.25769413409802 2.55253554396302 0.0109652079599149 -74.942389821039 13.043732950042 -5.74547103256953 1.52448939745327e-08 CFAP43 other 1.74824821250014e-08 0.000207269578477747 1 2.55253554396302 -5.74547103256953 4.63349768111247e-20 61.8198696172327 6.67852438631536 9.2565162663634 4.77892897453725e-19 -1.25212559737444 22.2635146896719 -0.0562411467743368 0.955170276995062 LHFPL5 other 5.49393820049505e-16 1 6.50173286985793e-15 9.2565162663634 -0.0562411467743368 0.00140485302288996 1277.2395809075 585.650400913997 2.18089081628591 0.0296190893334852 -2945.55005076658 1345.95269061032 -2.18844991455898 0.0290613381724854 RPL37A essential 1 1 1 2.18089081628591 -2.18844991455898 3.14155508526448e-06 46.3368013593381 13.2090896038772 3.5079481439612 0.000489500527572241 -105.978147074985 40.9218024952054 -2.58977221463796 0.00986508885694659 HOXC6 other 0.0200336967787316 1 1 3.5079481439612 -2.58977221463796 6.58488148866114e-13 53.6659978838701 7.97451738812876 6.72968598247209 4.33618040279095e-11 -56.465025621585 25.5828715310639 -2.20714181959686 0.0277224621658425 TXNRD3 other 6.26288078386561e-09 1 5.04384504452644e-07 6.72968598247209 -2.20714181959686 0.0397460562535143 240.445504118627 201.422753483644 1.193735563436 0.233119516955523 -497.681910465999 359.995962105683 -1.38246525754057 0.167415575802078 CFD other 1 1 1 1.193735563436 -1.38246525754057 0.00179718452552409 0.867998584389716 1.50084425605312 0.578340211443629 0.563292266385128 -11.0720040922636 3.49762886650993 -3.16557431186564 0.0016412164558866 STPG3 other 1 1 1 0.578340211443629 -3.16557431186564 2.42131749328899e-12 370.068904073668 52.9845114546137 6.98447327179128 8.44011811378571e-12 14.9167933030159 98.3926702030388 0.151604720882503 0.879555330338607 MCMBP essential 2.25352019100406e-08 1 1.00344564254798e-07 6.98447327179128 0.151604720882503 1.41771104212379e-16 354.223754729817 47.1071040358332 7.51954003498852 2.28851620788186e-13 -410.867252177977 215.624441856884 -1.90547624675444 0.0572460681681528 EME2 other 1.53764939628746e-12 1 2.82700407159646e-09 7.51954003498852 -1.90547624675444 3.29188732616088e-22 -2.52529779555253 2.91485831593605 -0.866353531403662 0.386686867496553 -73.849287720333 7.23400209770385 -10.2086350989273 1.8246933012739e-22 KLHDC1 other 4.07173543372839e-18 2.82973437161557e-18 1 -0.866353531403662 -10.2086350989273 3.83923136637549e-30 208.83465420136 19.2029906983278 10.8751109388157 4.76690690769255e-25 -52.3312068131814 45.6147388186424 -1.14724337283269 0.251788147826109 TAF13 other 5.25782735625124e-26 1 6.83050090803266e-21 10.8751109388157 -1.14724337283269 3.83709378652608e-26 66.7830016502801 7.08186105532545 9.43014853419927 1.14899029368751e-19 -169.080687658325 40.1477645355699 -4.21145958222714 2.96592377286863e-05 ZNF780A other 5.03656930419413e-22 0.347161377614273 1.57400180332252e-15 9.43014853419927 -4.21145958222714 4.81435643704036e-10 182.509074333034 31.1052636274352 5.86746592213604 7.77002311958592e-09 -11.1212884633731 60.3380595650574 -0.184316309532328 0.853835292903822 ATAD3A other 4.01421039720425e-06 1 8.35432885817878e-05 5.86746592213604 -0.184316309532328 2.50587550250268e-37 58.7777469208883 7.84523735864749 7.49215660837845 2.7523836513797e-13 -84.7419632446547 14.5938137845197 -5.80670443626903 1.08311032463987e-08 FAM118B other 3.62399715171937e-33 0.000147833728210096 3.39368904215116e-09 7.49215660837845 -5.80670443626903 1.0270527869521e-22 32.7777285393813 3.59675783238211 9.11313190014598 1.56084718873679e-18 -47.4141750095482 15.9560577081183 -2.97154697462797 0.00309503800947598 ZNF461 other 1.28186458339491e-18 1 2.11182624636087e-14 9.11313190014598 -2.97154697462797 0.00669685016096522 3.87272029153307 7.56744515168103 0.511760602674838 0.609026620243629 -43.9070445066758 15.7350196990986 -2.79040289407399 0.00544932521520956 CCDC180 other 1 1 1 0.511760602674838 -2.79040289407399 2.98174903400807e-12 107.864468399681 14.4410781623468 7.46928083811109 3.34356080926095e-13 57.2813422096261 103.289046728048 0.554573248801913 0.579420530805851 SLC9A8 other 2.76616857884929e-08 1 4.11191108322911e-09 7.46928083811109 0.554573248801913 1.21219143534246e-11 133.046460809671 41.0579977439107 3.24045175411417 0.00126860815383612 -411.504815066191 90.6081736046327 -4.54158602580144 6.92357670985598e-06 OCLN other 1.09363911296597e-07 0.0844399415534036 1 3.24045175411417 -4.54158602580144 0.0307733704870489 -3.35491151450628 5.50154090329981 -0.609813063917058 0.542242633849541 -46.5292556435049 17.6510372922321 -2.63606352834469 0.00862910375260465 HIST4H4 other 1 1 1 -0.609813063917058 -2.63606352834469 0.431341811562084 23.803572799351 26.1371749788332 0.91071712297247 0.362846315589393 -52.1941217744666 88.5865239937679 -0.589188055038015 0.555978820199792 CYP2A13 other 1 1 1 0.91071712297247 -0.589188055038015 9.77195872732615e-12 24.3467248044913 7.36308033835825 3.30659502350614 0.00100657492405263 -185.091674705944 33.1277785735939 -5.5872045357572 3.64848659053696e-08 ZNF181 other 8.85947647257462e-08 0.000489882294511398 1 3.30659502350614 -5.5872045357572 7.46902882135063e-14 71.3121036669418 11.7259500631208 6.08156296786771 2.29622273688722e-09 -147.440875532273 42.2135572739233 -3.49273752447657 0.000518508276252631 ZNF44 other 7.38388189278723e-10 1 2.51734898644945e-05 6.08156296786771 -3.49273752447657 5.05255740192001e-27 613.512760268789 54.6574711808719 11.224682500194 3.17846140836912e-26 -691.908572131433 376.430769241185 -1.83807655661675 0.0666453673202479 GPAA1 other 6.70625943956843e-23 1 4.58493058157246e-22 11.224682500194 -1.83807655661675 0.0249597926183796 -18.9666742121155 12.2493880715916 -1.54837728229889 0.122109830454445 -77.4359926370003 29.2230455941033 -2.64982622662114 0.00828630910446655 ADAMTSL2 other 1 1 1 -1.54837728229889 -2.64982622662114 0.16026543698243 6.0262031375611 6.65108812717609 0.906047705628538 0.365314694991904 27.9925997355502 14.6325691311124 1.91303382780752 0.0562722907286999 SGTB other 1 1 1 0.906047705628538 1.91303382780752 5.86558468181851e-21 21.6353175035293 2.60009282901767 8.32097887509011 7.117071834131e-16 -42.4508692081525 11.7359916464649 -3.61715230267223 0.000325703604837878 ZNF790 other 7.08269350329586e-17 1 9.24436460535276e-12 8.32097887509011 -3.61715230267223 0.0456419427389399 34.8164741024449 14.0056165575839 2.48589370980546 0.0132228826108015 18.4314700882487 40.7651153265822 0.452138303561473 0.65135024465493 FAM49A other 1 1 1 2.48589370980546 0.452138303561473 7.5732744477648e-25 715.693717063278 191.797441822292 3.73150814871867 0.000210499141402131 -2817.18271378056 351.935339490339 -8.00483042669233 7.37158335170334e-15 MYO1C other 9.77028136506137e-21 1.10603236608957e-10 1 3.73150814871867 -8.00483042669233 4.83447164547381e-19 49.8540922925948 8.01766751628512 6.21802939462548 1.01115094762989e-09 -80.749680138861 17.0403183035266 -4.73874247537674 2.75604382415676e-06 NKIRAS1 other 5.59590092963594e-15 0.0343099895669275 1.12601769528065e-05 6.21802939462548 -4.73874247537674 0.229593492422154 -33.3005846485986 30.5625003643766 -1.08958966876327 0.276396678049161 -140.60804123969 86.7923639556385 -1.62005082971997 0.105825279132725 UGT2B17 other 1 1 1 -1.08958966876327 -1.62005082971997 3.71001692162693e-32 42.8589371740405 138.775157865767 0.308837243157719 0.757564230485295 -2751.53327333977 279.554855213718 -9.84255226487207 3.87949519891437e-21 KIF13B other 5.17881262089903e-28 5.99575982992216e-17 1 0.308837243157719 -9.84255226487207 0.0858484510844494 913.311579030484 423.921054054534 2.15443788482606 0.0316425960204795 274.242651859065 810.874930363441 0.338205858375899 0.735338065182091 NRAP other 1 1 1 2.15443788482606 0.338205858375899 1.32345478927266e-11 257.056416276441 47.8261428597757 5.37480969414824 1.13909559038441e-07 -258.268659676461 107.183176692278 -2.40960071950422 0.0163010307486533 ADH5 other 1.19177103774003e-07 1 0.00115868803453902 5.37480969414824 -2.40960071950422 3.51784888451178e-13 331.360908422918 42.6200913308639 7.77475829065055 3.93807941834334e-14 419.274740322239 165.532677407149 2.53288200788887 0.0115991586678486 HIST1H2BK other 3.38522598156569e-09 1 4.95174106062492e-10 7.77475829065055 2.53288200788887 2.16383765508655e-19 133.165732923223 14.0467421608429 9.48018632351914 8.0168681280403e-20 44.5241447667941 51.4691256542678 0.865065108466675 0.387387898521701 TEAD4 other 2.53060813762372e-15 1 1.10007464452969e-15 9.48018632351914 0.865065108466675 8.17137571821207e-37 198.234494896027 31.7547904566984 6.24266424199349 8.84459752572257e-10 -400.037526369881 68.4937286241446 -5.84049860338403 9.10428533581297e-09 SPG7 other 1.17774038226591e-32 0.00012463766624728 9.8670329996961e-06 6.24266424199349 -5.84049860338403 0.230038024270168 14.4254807593007 8.49995067636504 1.69712523149249 0.0902449721545741 20.085533555664 36.0122321162317 0.557741977526877 0.577250025134362 ZNF677 other 1 1 1 1.69712523149249 0.557741977526877 7.47442354504233e-05 467.170019480277 111.670850264665 4.18345538135568 3.34874983329756e-05 681.764934382954 265.01700698646 2.57253276736985 0.0103607783498487 ERO1A other 0.413410366276291 1 0.289097573108579 4.18345538135568 2.57253276736985 4.16481791676211e-14 24.9271867107232 6.11924505720133 4.07357222626475 5.33934924257669e-05 -127.779770233582 22.4524948063463 -5.69111679284141 2.09286408311981e-08 ZNF823 other 4.1544058719702e-10 0.000283059867241954 0.4525632418008 4.07357222626475 -5.69111679284141 2.11397971992396e-07 -0.0532220970969587 4.00222436804847 -0.013298129290765 0.989394825041015 -73.6492435237213 13.7833370335392 -5.34335359750035 1.34483483455776e-07 ZNF311 other 0.00149356480886012 0.00177007160924492 1 -0.013298129290765 -5.34335359750035 1.85344076146104e-09 43.5863600724767 8.4531622226164 5.1562195217148 3.53153609659773e-07 -104.488215152138 36.0173742238833 -2.90105032373101 0.00386936845447161 ZNF347 other 1.4983215115651e-05 1 0.00349692704285107 5.1562195217148 -2.90105032373101 0.0253465164649278 97.6174616732479 71.003239168093 1.37483110372118 0.169746703213257 -158.834249463442 151.548329603477 -1.04807654349624 0.295066207472779 PLCG2 other 1 1 1 1.37483110372118 -1.04807654349624 4.51070313869579e-07 57.9182914883458 14.6653803154982 3.94932079784786 8.87385282398527e-05 -75.4125948849739 34.647692819063 -2.17655459134879 0.0299455726887392 FCHSD1 other 0.00310110840785335 1 0.736529784390777 3.94932079784786 -2.17655459134879 8.38644695626542e-15 42.1200307348119 5.24550300821452 8.02974103128935 6.07335355823865e-15 -8.46390415966238 20.9774329736905 -0.403476639409486 0.686756156245508 ZNF71 other 8.5944308407808e-11 1 7.75749449993823e-11 8.02974103128935 -0.403476639409486 2.68702223371747e-05 2129.35910820865 462.093227961884 4.60807252597152 5.08046652438683e-06 -3313.77888273793 4770.94407926688 -0.694575083606334 0.487621465590308 S100A6 other 0.156626526003391 1 0.046755533423932 4.60807252597152 -0.694575083606334 7.23232966345984e-08 -524.473602858917 296.198106594648 -1.77068519744681 0.0771771564481025 -3868.36638079664 664.714434218021 -5.81959136384248 1.01215807159125e-08 RPL12 essential 0.000528538651805645 0.000138351886805808 1 -1.77068519744681 -5.81959136384248 0.293265150387467 12.9897106076377 9.07869432251401 1.43079061219463 0.15307079539323 -36.2119343289138 66.2396713955337 -0.546680464531342 0.584824933215205 DNM3 other 1 1 1 1.43079061219463 -0.546680464531342 7.21125779813004e-37 275.800002401125 20.8060407712322 13.2557657381151 7.12382969103513e-35 -76.2158939318292 78.1542384317556 -0.975198472420418 0.329903372059983 ZNF121 other 1.03979126191237e-32 1 1.06401520265301e-30 13.2557657381151 -0.975198472420418 1.47262116850144e-10 597.521233608444 92.1020159090819 6.487602119353 1.97995625488864e-10 -1490.04220938988 753.487586962164 -1.97752721500999 0.0484920033905965 MPZL1 other 1.26100550658779e-06 1 2.25893209120245e-06 6.487602119353 -1.97752721500999 5.82125783083984e-11 116.377290283474 36.3548595993109 3.20114811516643 0.00144917481609871 -390.028904284537 79.9607709414847 -4.87775317436547 1.41313243934964e-06 VPS13A other 5.0813759605401e-07 0.0178167737953202 1 3.20114811516643 -4.87775317436547 0.000343946849465516 156.272283953443 41.6485900412992 3.75216264940738 0.000194739377593081 31.7285937378455 84.9736564685067 0.373393296893195 0.709005614989861 MBP other 1 1 1 3.75216264940738 0.373393296893195 0.0125281697313915 -98.5007004287484 119.488490492256 -0.82435304038871 0.410104984315524 -1221.27839857768 410.960734113578 -2.97176420324418 0.00309363043957618 ELOVL2 other 1 1 1 -0.82435304038871 -2.97176420324418 7.14439514388013e-06 22.8565234721779 4.65275877875734 4.91246689523896 1.19894357806728e-06 17.5323651999571 9.98499371674618 1.7558714303999 0.0796857907034292 GOLGA6L9 other 0.0439808965057261 1 0.0114858794778846 4.91246689523896 1.7558714303999 0.000640016232863619 1.7849173303149 0.893563649557207 1.99752679196316 0.0462701301063915 -11.2002413966354 3.46406183083986 -3.23326832590628 0.00129871439453211 LEKR1 other 1 1 1 1.99752679196316 -3.23326832590628 0.00329287866450467 85.8816143161564 55.7123455815698 1.54151855247981 0.123774244325967 -275.325825943251 115.914757753862 -2.37524394027453 0.0178842510177662 C1orf122 other 1 1 1 1.54151855247981 -2.37524394027453 0.000134942747138808 50.8700161621271 18.0002222532107 2.82607711430082 0.00488605502413765 -40.059790516871 29.373096683151 -1.36382591692656 0.173188482592873 SNHG12 other 0.721403926204066 1 1 2.82607711430082 -1.36382591692656 0.0815569298326698 7.94778577049638 11.2588716480662 0.705913169536973 0.480570250123983 -28.0589946748543 19.2212380355534 -1.45979122796116 0.144974198877242 PCDH20 other 1 1 1 0.705913169536973 -1.45979122796116 0.325510558984269 1.09486028340279 2.33993809766989 0.467901387858529 0.6400418180939 -10.2111862059899 8.24202027563513 -1.23891787019452 0.215908240473987 KEL other 1 1 1 0.467901387858529 -1.23891787019452 6.78061471942818e-14 118.139716028983 26.9665382394343 4.38097448697447 1.41840495523748e-05 -289.66293430755 59.3665148169422 -4.87923091326367 1.40164617520442e-06 NOL8 essential 6.71552081812167e-10 0.0176733566231526 0.126238041016136 4.38097448697447 -4.87923091326367 2.28948327101594e-11 43.0366698147115 12.794404417646 3.36371029161431 0.000825185740560672 -213.231528185178 39.4630835926391 -5.40331643584363 9.93817931830196e-08 IRAK4 other 2.03832695618549e-07 0.00131561617815681 1 3.36371029161431 -5.40331643584363 3.73054455643066e-06 20.4422149746024 5.19939139410631 3.93165534677276 9.53443972971563e-05 -34.8666699291852 17.4052217611446 -2.00323043323823 0.0456517867369131 CCDC151 other 0.0236143470422061 1 0.789642298415049 3.93165534677276 -2.00323043323823 2.24548558687399e-18 215.348805672032 28.1618093294187 7.64683842408776 9.62333871033403e-14 -234.728280268256 72.9895528939095 -3.21591612719473 0.00137884997436113 MRPL42 other 2.55940447191898e-14 1 1.198490602985e-09 7.64683842408776 -3.21591612719473 0.0276677876561734 28.1653995277143 18.5771187664506 1.51613390008464 0.130067407054348 -52.3492063249439 36.4264214753343 -1.43712185289438 0.151259328184058 ENTPD7 other 1 1 1 1.51613390008464 -1.43712185289438 0.968853301387203 -0.384386776191507 4.76330621856089 -0.0806974732579001 0.935730025690257 -4.72673991316442 18.9700578344877 -0.249168450323391 0.803380937021132 FCGR1B other 1 1 1 -0.0806974732579001 -0.249168450323391 2.11622212138516e-18 75.7690670503808 8.60306668585322 8.80721605645281 1.7781825936874e-17 -108.804684797283 53.6491886763807 -2.0280769846047 0.043046444940567 ZNF335 essential 2.41397457386405e-14 1 2.37191776171963e-13 8.80721605645281 -2.0280769846047 0.735263075953207 -2.20916345561172 7.54552568851664 -0.292777938450835 0.769811205957803 -12.0063292353287 15.4223802577284 -0.778500402317088 0.436635814936053 TUBA3C other 1 1 1 -0.292777938450835 -0.778500402317088 1.54881407662116e-11 33.7708876697545 6.46406430602192 5.22440465796319 2.53803635171999e-07 -98.959267714102 26.3097170810797 -3.76132010120578 0.000188342166526832 ZNF273 other 1.38944110813685e-07 1 0.00253397549355724 5.22440465796319 -3.76132010120578 6.33522878568484e-09 98.6938549079897 26.3357117364299 3.74752943439411 0.000198352665409137 -232.905862167346 63.9639804297675 -3.64120338669475 0.000298209400924421 ZNF84 other 4.96428527646264e-05 1 1 3.74752943439411 -3.64120338669475 8.59073834835723e-44 172.050249221932 16.6334095590428 10.3436549560819 6.53145478059299e-23 -158.610016665317 38.3208938134565 -4.13899575091905 4.07483570474348e-05 MAK16 essential 1.27761460716769e-39 0.472477199965007 9.21784213185088e-19 10.3436549560819 -4.13899575091905 0.0760286505519316 13.8520982372865 7.19299773137957 1.92577542140135 0.0546542302164431 46.1761489828149 29.2655802117635 1.57783131749611 0.115186726265909 ZNF667 other 1 1 1 1.92577542140135 1.57783131749611 0.0143920455798437 150.796056917943 55.882553687252 2.69844606175081 0.00718123946024721 388.711201284217 211.301315012828 1.83960616270002 0.0663667975362757 SIRPA other 1 1 1 2.69844606175081 1.83960616270002 3.7525012839878e-08 134.550637687051 22.6867622658619 5.93079947285017 5.39675838874807e-09 110.428582810151 64.61100810464 1.70912954385896 0.0880036516268628 GRK6 other 0.000280274320901048 1 5.83767354910878e-05 5.93079947285017 1.70912954385896 1.88842549209147e-08 58.3424523764839 9.648782400354 6.04661292541361 2.77495467516497e-09 31.8383278398161 28.4110150079646 1.12063324139918 0.262945854990283 PRIM1 essential 0.000143746948458003 1 3.03330295542283e-05 6.04661292541361 1.12063324139918 2.68443655706571e-18 174.921746931984 34.314438600572 5.09761354303692 4.7546355929201e-07 -347.354373838645 65.4737287391362 -5.30524808236586 1.64015059682462e-07 MARCH5 other 3.05193592172801e-14 0.00214974538725804 0.00467047854292542 5.09761354303692 -5.30524808236586 1.72940692929608e-06 85.6284962172298 20.9289148733913 4.09139684189248 4.95535223948379e-05 -278.115424607043 127.138324926633 -2.18750266505032 0.0291419754695779 NPIPB13 other 0.0113034036898792 1 0.420858065699358 4.09139684189248 -2.18750266505032 0.725701634367876 14.0598554959683 36.9266532592219 0.380750873827349 0.703536206967931 -64.435299659475 119.137071840636 -0.540850120486988 0.588831466953036 AKR1B10 other 1 1 1 0.380750873827349 -0.540850120486988 0.0898463677155972 19.4069310531719 8.83222484323646 2.19728679892398 0.0284223748506123 17.1825072740758 34.439647036529 0.498916474255699 0.618040653849517 SULT1C4 other 1 1 1 2.19728679892398 0.498916474255699 0.5131321852085 158.724416686389 241.71805199027 0.656651066726195 0.511682980083617 -669.305668670591 929.370100550238 -0.720171294809598 0.471728847063157 CYP2A7 other 1 1 1 0.656651066726195 -0.720171294809598 6.50516144281391e-19 22.9681617524379 9.4396293163939 2.43316352608771 0.015294682233658 -148.602369575639 20.9279153455053 -7.10067711581958 3.9795283120988e-12 ZBTB14 other 7.49870111675402e-15 5.80613180735214e-08 1 2.43316352608771 -7.10067711581958 8.86110940413394e-46 835.295052981573 54.5866141044528 15.3021957248203 3.20241271392274e-44 -53.7916443608028 256.530348794124 -0.209689202909761 0.833988757419794 CD2AP other 1.32624224451673e-41 1 4.87118997914788e-40 15.3021957248203 -0.209689202909761 1.35410135772046e-16 21.6443163707207 25.1154686824296 0.861792254184079 0.389181558222798 -382.661196231557 51.7524439232785 -7.39407006167362 5.41404222888603e-13 SFI1 other 1.4691999731267e-12 7.97650841581778e-09 1 0.861792254184079 -7.39407006167362 1.28029690650522e-09 104.452445575676 16.1248691112351 6.47772362399507 2.09194668959335e-10 123.012680362643 68.3410664775857 1.79998186599836 0.0724194540110749 ZNF649 other 1.04190562251394e-05 1 2.38502842080538e-06 6.47772362399507 1.79998186599836 8.1609791583922e-07 18.9949058311989 5.0167949022229 3.78626318225256 0.000171508121899719 -56.7879024716034 19.7465956107123 -2.87583255317168 0.00420159345400909 ZNF248 other 0.00549560336526131 1 1 3.78626318225256 -2.87583255317168 0.248672374618064 -2.48699107222369 5.86898097218305 -0.423751769516918 0.671913739089582 -22.9012175410009 13.8348667364021 -1.65532621147289 0.0984329653375571 CHSY3 other 1 1 1 -0.423751769516918 -1.65532621147289 0.00805251444263285 6.28439618445326 6.47615764204603 0.970389624806572 0.332318699406693 -37.7369522149314 15.1029602587441 -2.49864606464041 0.012784808358122 TOR4A other 1 1 1 0.970389624806572 -2.49864606464041 1.04762621866382e-05 -20.8859447104621 24.318431300974 -0.858852466755355 0.390798804118362 -250.071310085263 52.3608758914525 -4.77591915390562 2.30136375936319e-06 LPAR1 other 0.0636013877350807 0.0287463347182056 1 -0.858852466755355 -4.77591915390562 0.479204505784027 715.705110595154 827.124799245821 0.865292772321347 0.387258837121169 1929.36978483571 1671.3806022972 1.1543569323372 0.24885978433698 MB other 1 1 1 0.865292772321347 1.1543569323372 2.26218554216601e-09 86.257581051422 17.9190573813203 4.81373429504954 1.92758444808249e-06 -128.950128083396 45.5219649482655 -2.83270127354881 0.00478870533345009 HIBCH other 1.81970205011834e-05 1 0.0182291661255161 4.81373429504954 -2.83270127354881 1.04614207814531e-41 220.911661817654 15.0016059831646 14.7258674881589 3.05755591779053e-41 -28.9099115504565 65.1510205910464 -0.443736894498159 0.657418466924311 ZNF544 other 1.54326879367995e-37 1 4.63097419308554e-37 14.7258674881589 -0.443736894498159 6.75647823315712e-08 51.5345242038567 35.4008836963599 1.45574117996257 0.146048537880986 -299.987898747674 68.1377305288399 -4.40266936423281 1.290715828858e-05 TMEM229B other 0.000494776901014096 0.154834270829806 1 1.45574117996257 -4.40266936423281 0.000582899107306827 7.41363764843388 33.2723714174302 0.222816629311554 0.823762013937261 -366.984972149651 97.8805122686614 -3.7493160144315 0.000196344862090156 SOWAHC other 1 1 1 0.222816629311554 -3.7493160144315 1.0802371682636e-23 260.764964151384 48.3143838491698 5.39725322722634 1.0132853966829e-07 -481.469292918259 87.7360169453269 -5.48770402032598 6.26028027772815e-08 ZNF770 other 1.36855246847316e-19 0.000834057141401722 0.00103419986776185 5.39725322722634 -5.48770402032598 9.29792994371944e-07 2.45561515469432 1.45053307050361 1.69290532193227 0.0911014267886509 -12.3253496180429 3.21906884275921 -3.82885555422862 0.000145224313377507 ZNF876P other 0.0062305428552864 1 1 1.69290532193227 -3.82885555422862 1.06829295046985e-06 4.20821209385101 1.00754238391642 4.17670974544343 3.452151458562e-05 -13.4126171501852 5.96220414528574 -2.24960716261123 0.0248788666872381 NPIPB6 other 0.00710842129242637 1 0.297679020271801 4.17670974544343 -2.24960716261123 6.60296212887566e-09 104.343306351893 37.1498530219736 2.80871384040672 0.00515408596308082 -328.307699565313 75.5390392762815 -4.34619903444282 1.65553926437255e-05 MIER1 other 5.16879875448387e-05 0.197423057276427 1 2.80871384040672 -4.34619903444282 2.57107879826923e-31 497.358374637595 41.7907800995524 11.9011507670545 4.13941499802084e-29 -175.213036361855 159.390574727402 -1.09926848975551 0.272150051096549 MAN1A2 other 3.56248678288185e-27 1 6.0596896156027e-25 11.9011507670545 -1.09926848975551 7.68722194731497e-07 117.062580723632 37.0471873964401 3.15982369919073 0.00166757758841718 -293.605817700219 97.2904010940918 -3.01782924521265 0.00266671350271708 SVIP other 0.00518810609224287 1 1 3.15982369919073 -3.01782924521265 2.31336455719469e-28 104.388074889689 8.75785378146488 11.9193671753935 7.16180203426722e-29 -11.1550622639072 59.4197842250184 -0.187733133154166 0.851165188377576 ZNF251 other 3.1156393856298e-24 1 1.04755678355227e-24 11.9193671753935 -0.187733133154166 8.28201642149718e-11 208.992795680187 47.7800061982392 4.37406380428409 1.46154435634419e-05 -756.749123883782 187.37200138429 -4.03875241921406 6.14482234734283e-05 DDRGK1 other 7.17388262430086e-07 0.703950848111595 0.129916677835435 4.37406380428409 -4.03875241921406 6.08558109770355e-70 1219.17312534225 58.5088566903768 20.8374115357269 3.32373837322068e-71 788.087207142092 167.821813279439 4.69597599824436 3.36926605228023e-06 TFDP1 other 9.41804530680601e-66 0.0417553141859089 5.16176569361171e-67 20.8374115357269 4.69597599824436 6.06449993992319e-41 96.1947141226941 6.74640884503261 14.2586546905651 2.11515193869697e-39 -39.1403183897497 35.104370743747 -1.11496994706055 0.265357432423782 ZNF607 other 8.91663426166907e-37 1 3.19345639704469e-35 14.2586546905651 -1.11496994706055 0.261045208594323 1.1233726704261 0.764552140177491 1.46932120308408 0.14232373530046 -2.27411211964585 4.46598852620595 -0.509206888083478 0.610813692868796 BPIFA1 other 1 1 1 1.46932120308408 -0.509206888083478 0.0109996453346379 19.8101169785357 6.89439133088238 2.87336706429751 0.00422256925504268 -20.477215735877 41.9693067958848 -0.487909315144678 0.6258139647152 ZNF334 other 1 1 1 2.87336706429751 -0.487909315144678 0.0612079840499095 -5.32928104796369 26.6840538602777 -0.199717819333926 0.841775363207141 -148.091192502539 65.2655620583345 -2.26905565250744 0.0236528743979127 HSD17B11 other 1 1 1 -0.199717819333926 -2.26905565250744 3.50902131097258e-16 53.2300399769103 35.1723141587358 1.51340738447514 0.130761245980546 -596.48593650228 78.2289759563224 -7.62487210410777 1.1075623120098e-13 SZT2 other 3.7627235517559e-12 1.64406549594735e-09 1 1.51340738447514 -7.62487210410777 0.900194757870501 -2.67801899487324 10.7028883638714 -0.250214605985535 0.802516203107523 -17.6523222554596 41.9593503142748 -0.420700561930632 0.674140505228079 SULT1C2 other 1 1 1 -0.250214605985535 -0.420700561930632 3.4927635800218e-11 41.0987448774904 8.97950768044738 4.57694857447272 5.84420381701232e-06 -52.7004915336086 17.7694021590842 -2.96579992178672 0.00315077446547387 RPS6KL1 other 3.08271313572724e-07 1 0.053579660594369 4.57694857447272 -2.96579992178672 4.63432420937301e-49 175.299232434573 34.2314005242124 5.12100672920411 4.28482977588456e-07 -714.659342416417 61.9642835327632 -11.5334076611819 1.44813222559419e-27 QRICH1 other 6.98948777257638e-45 2.26183772315556e-23 0.00422269974413424 5.12100672920411 -11.5334076611819 1.56186378071284e-57 571.752568101659 33.2449513964966 17.1981772896173 6.59931898185732e-53 -487.444680357385 147.740694220118 -3.2993257743269 0.00103493727929548 DDX42 essential 2.39183819378364e-53 1 1.01431532751147e-48 17.1981772896173 -3.2993257743269 3.65128170004124e-28 802.770059325384 81.2164616735625 9.88432693056733 3.31568464453027e-21 -1013.42874239036 315.384200830677 -3.213314870311 0.00139460821257345 RPL23A essential 4.90914824570545e-24 1 4.60880165589708e-17 9.88432693056733 -3.213314870311 5.50270185711525e-10 46.0017157911704 19.7037726690193 2.33466537418491 0.0199238050289347 -300.169550274947 56.6774576768146 -5.29610117635427 1.72017743138931e-07 SLC29A3 other 4.57329551344849e-06 0.00225188427543175 1 2.33466537418491 -5.29610117635427 6.96159462309104e-23 149.789453072486 18.1458191339147 8.25476391928366 1.16630448929092e-15 -163.410412546898 43.0636165551733 -3.79462817149916 0.000164529673450512 STYX other 8.70686639509996e-19 1 1.5077984437553e-11 8.25476391928366 -3.79462817149916 4.14721535544294e-22 514.086897220147 57.5835419802828 8.92767064235429 6.92531445413049e-18 -616.085409512191 206.097615419659 -2.98928936299292 0.00292458443254566 UBL5 essential 5.1205667993654e-18 1 9.30000478045183e-14 8.92767064235429 -2.98928936299292 3.57989302069252e-45 376.298377939986 24.2304442171612 15.5299826353771 4.96361279323268e-45 -14.2550527169504 106.505481903058 -0.133843370897336 0.89357772083152 HELZ other 5.34907615151877e-41 1 7.55958228409337e-41 15.5299826353771 -0.133843370897336 5.41593426754414e-11 21.4028028467917 11.3098199389785 1.8924088059995 0.0589731206283457 -147.879483674275 25.1543930400655 -5.87887306359308 7.2541144447079e-09 TMEM116 other 4.73406814326033e-07 9.95989913258395e-05 1 1.8924088059995 -5.87887306359308 0.336769779026096 -8.73172546991693 6.77220539924772 -1.2893474068118 0.197829325977547 8.63521178161032 23.8071508720794 0.362715044232259 0.716959682419134 CARD11 og 1 1 1 -1.2893474068118 0.362715044232259 4.53465804457422e-17 30.9749966550502 4.15689967096823 7.45146602199217 3.81684299581265e-13 -31.9088257262837 11.9557538251866 -2.66890956378366 0.00784480951657036 ZNF485 other 4.99311197288068e-13 1 4.68555646165961e-09 7.45146602199217 -2.66890956378366 4.84358822607507e-06 543.856671481613 110.424189119649 4.92515884261845 1.120440900372e-06 804.241748774488 424.649216411374 1.89389669801107 0.0587699432684453 PEG3 other 0.0302869571776474 1 0.0107528713208701 4.92515884261845 1.89389669801107 1.45073427418853e-39 313.665705987302 25.0557523401963 12.5187103435763 9.35673129658805e-32 -195.410843837876 73.398487466453 -2.66232793866753 0.0079911287936612 SDAD1 essential 2.12068336200879e-35 1 1.38395412607834e-27 12.5187103435763 -2.66232793866753 1.4651738264282e-09 55.1586606328899 26.7423728458956 2.06259410676624 0.0396262199003197 -498.949051061317 95.2557986661767 -5.23799136690754 2.3258876671919e-07 ZKSCAN8 other 1.18957462967706e-05 0.00302807315391713 1 2.06259410676624 -5.23799136690754 4.44573256991792e-05 34.9989096677777 14.239550182418 2.45786624011424 0.0142919359809758 -91.0293505868209 32.0008624544585 -2.84459053928211 0.00461679731990744 FAM109A other 0.25349567113672 1 1 2.45786624011424 -2.84459053928211 1.89996909410555e-56 69.7370847504572 4.5113470266146 15.4581512659179 5.46825947843263e-45 -58.1174311965105 15.5355938768979 -3.74092111682539 0.000202701944364685 HYLS1 other 2.9052427417968e-52 1 8.3270655337572e-41 15.4581512659179 -3.74092111682539 0.000113459803423404 3.37906693851997 2.82123965928438 1.1977241732725 0.231563850508743 -37.5188997294295 10.1667321213219 -3.69035982080652 0.000247277210559544 ZNF442 other 0.612229099272686 1 1 1.1977241732725 -3.69035982080652 6.34179612783564e-07 48.8681847047083 9.05138927258284 5.39897061468042 1.00340356191428e-07 21.413472878387 37.9975280213337 0.563549104203947 0.573293679301818 ZNF813 other 0.00430960185295485 1 0.00102457537707067 5.39897061468042 0.563549104203947 1.56482779803654e-16 105.135272813113 13.198472480439 7.96571519688592 9.84922766484339e-15 -63.1077590815394 40.7918488369375 -1.54706787951211 0.122434884423222 HOXC4 other 1.69408257415435e-12 1 1.25390517401121e-10 7.96571519688592 -1.54706787951211 1.42300386298578e-15 480.11319388789 74.1425050888272 6.47554588710869 2.12924305907025e-10 -387.100296795505 158.978785223963 -2.43491794361225 0.0152185192932478 PIM3 other 1.49685776347474e-11 1 2.42669831442237e-06 6.47554588710869 -2.43491794361225 2.49539031037345e-23 232.042342868164 34.2350605909379 6.77791535527721 3.21789908957634e-11 -615.063159404666 104.898626662273 -5.86340526063222 7.92682639402539e-09 ASNA1 essential 3.14244501785328e-19 0.000108756058126028 3.76011508616995e-07 6.77791535527721 -5.86340526063222 8.1966914468135e-06 688.175806562901 149.988677635864 4.58818503776414 5.61519660097604e-06 -1550.1711162654 1282.38609465687 -1.20881778329028 0.227284344848015 ASPH other 0.0501883417288391 1 0.0515250440105561 4.58818503776414 -1.20881778329028 0.000421604353102939 -102.81764448187 52.614684528773 -1.95416251950809 0.051193023641786 -665.246129977106 177.492761468495 -3.74801836690781 0.000197264797223602 SPRED2 other 1 1 1 -1.95416251950809 -3.74801836690781 6.26774823653413e-27 415.116398759233 55.8628090895898 7.43099757288415 4.21383553539553e-13 -323.805824201336 122.031077099899 -2.65347018068402 0.00820023344190782 WWP2 other 8.30978061199695e-23 1 5.16447683218076e-09 7.43099757288415 -2.65347018068402 0.00879258740454301 600.974088351706 199.430916481248 3.01344495104005 0.00270285482983195 -142.111811231413 673.244617734147 -0.211084957069097 0.832899736982634 GFPT1 other 1 1 1 3.01344495104005 -0.211084957069097 1.32836047723532e-42 214.374235871812 15.5475655410404 13.7882831434887 5.6319758009009e-37 -191.199975878705 69.1233789588193 -2.7660681343806 0.00587988223733911 UVRAG other 1.96623917840372e-38 1 8.45472207231243e-33 13.7882831434887 -2.7660681343806 5.32540394215803e-08 36.0942577616435 9.7301421259595 3.70953037421169 0.000229685508686934 -75.8908171701722 23.5330728884378 -3.22485794906362 0.00133849098080617 ZNF26 other 0.000393707113443743 1 1 3.70953037421169 -3.22485794906362 7.33251157486627e-09 146.531833336191 30.8532575351644 4.74931482256563 2.61778517417763e-06 -236.960755955135 89.2367202602784 -2.65541758217903 0.00815451842810493 ITSN2 other 5.7244917864981e-05 1 0.024552207148612 4.74931482256563 -2.65541758217903 0.752485303181552 -2.58925198701099 4.33938766639278 -0.596686027170135 0.550966626823743 -18.2046389306745 38.6468444871806 -0.471051108369613 0.637794117919575 NTRK1 other 1 1 1 -0.596686027170135 -0.471051108369613 4.96848988025376e-15 452.068279196036 114.341461756988 3.95366888134443 8.71263319704383e-05 -1284.34151663126 232.925680393598 -5.5139541267454 5.4284939301776e-08 MGEA5 other 5.13294689529016e-11 0.000724921079435916 0.724106945006312 3.95366888134443 -5.5139541267454 0.0029485399491061 -6.61467529540792 40.2962293870165 -0.164151221988506 0.8696738644077 -238.845115431871 85.9841324933875 -2.77778130110505 0.00566454092320112 MT1F other 1 1 1 -0.164151221988506 -2.77778130110505 5.02855548464155e-12 153.740936195047 40.6220041925115 3.78467136841535 0.000171014505468166 -653.8594310003 135.539171836145 -4.82413624151962 1.82841965949043e-06 TCAF1 other 4.62325391257944e-08 0.022932039369329 1 3.78467136841535 -4.82413624151962 4.67112043609102e-19 29.8506394393691 3.78828084629016 7.87973243023986 1.89188707096329e-14 -44.937751637855 14.0123625491675 -3.207007489292 0.00142266585363099 ZNF69 other 5.40822324090618e-15 1 2.39304795606146e-10 7.87973243023986 -3.207007489292 6.16942854004186e-10 582.266423941583 89.4086384122499 6.51241797528377 1.67956686899058e-10 708.022140200872 214.746444260721 3.2970144983694 0.00104072430042463 TXNRD1 essential 5.11260543113269e-06 1 1.92108858475143e-06 6.51241797528377 3.2970144983694 8.58515898583544e-05 44.4638370367286 11.984501356838 3.71011156099196 0.00023025958000247 -27.8245229754354 27.9488946559993 -0.995550032225077 0.319947495563859 NRARP other 0.470552564013641 1 1 3.71011156099196 -0.995550032225077 6.71855040406028e-09 13.3055722182287 2.83581914742546 4.69196783240157 3.42746920228836e-06 -37.6703360646741 11.6440297412527 -3.23516316101588 0.00128959360284841 ZNF583 other 5.25860940125798e-05 1 0.0318857459888887 4.69196783240157 -3.23516316101588 1.16326630948373e-10 17.7871504073056 5.58342466456006 3.18570617066025 0.00152679470844268 -136.054357217521 25.7591922517866 -5.28177886509949 1.85314227165803e-07 ZNF568 other 9.99594739739367e-07 0.00242261289173854 1 3.18570617066025 -5.28177886509949 2.48073493109856e-33 172.712286777279 13.2523469949737 13.032581084904 5.75732308023807e-34 27.7338288531591 55.3729127217065 0.500855517435825 0.616676141324055 ZNF480 other 3.49684395887653e-29 1 8.57898712186275e-30 13.032581084904 0.500855517435825 2.51329527174009e-37 928.203942132782 68.4474174202269 13.5608321996162 3.48970198447221e-36 -524.468735986373 341.032118669776 -1.53788663083145 0.124671982667994 ZNF587 other 3.63447629246335e-33 1 5.23036533432695e-32 13.5608321996162 -1.53788663083145 0.656026143231859 422.475830765105 587.717077008134 0.718842190047946 0.472551411268101 -510.407278685964 1560.92764261431 -0.326989710958743 0.743803322430253 TPM2 other 1 1 1 0.718842190047946 -0.326989710958743 1.86322284045881e-05 6.23706423689974 1.33442889768409 4.6739577115905 3.74387157257994e-06 -0.163254182857587 8.25962754215282 -0.0197653201702405 0.98423795204969 FLVCR1-AS1 other 0.110545011124421 1 0.0347543598082596 4.6739577115905 -0.0197653201702405 0.000165706710941849 -12.8159880663779 29.2558333001481 -0.438066075059056 0.661515199718027 -239.468876226102 63.4556452554338 -3.77379940369601 0.000178753147279999 SH3BGRL2 other 0.874765727062021 1 1 -0.438066075059056 -3.77379940369601 3.58211746602622e-20 40.5506875475944 4.46700445331564 9.07782563715503 2.02864637407307e-18 -48.4380147302531 19.3203839567506 -2.50709379475499 0.0124632417737405 ZNF808 other 4.25519733789255e-16 1 2.7402955220979e-14 9.07782563715503 -2.50709379475499 3.97104013444911e-23 384.87790462097 61.0773274218154 6.3014856881819 6.1166858081264e-10 -427.069421164692 98.1140569495681 -4.35278526281113 1.60767859672528e-05 YTHDF2 other 4.98722930485464e-19 0.191812133375293 6.86475648246026e-06 6.3014856881819 -4.35278526281113 2.76737789147965e-34 16.6126338566868 3.37307664742553 4.92506859260558 1.12557926326041e-06 -69.8509996332848 7.42834149529029 -9.40331023790057 1.53914894489348e-19 NBR2 other 3.92912313032281e-30 2.3669032474572e-15 0.0107999330309837 4.92506859260558 -9.40331023790057 3.15904750933448e-07 102.518962008357 28.6625258206265 3.57675951693626 0.000379071235684943 -165.537008478334 64.2100755494821 -2.57805347621444 0.0101992027008807 TMA16 essential 0.0021996447807496 1 1 3.57675951693626 -2.57805347621444 0.0623545150197438 381.002656790922 210.566982832764 1.8094130982231 0.0709366507318614 1488.13969174069 735.908350499935 2.02218073857938 0.0436447793306506 HLA-DRB5 other 1 1 1 1.8094130982231 2.02218073857938 0.506991986176394 11.8542065874947 14.3020296454267 0.828847854562047 0.407554016322813 -18.5044300993507 34.1664968989915 -0.541595767165023 0.588318746817826 ATL1 other 1 1 1 0.828847854562047 -0.541595767165023 0.00201699974161202 13.9624084039911 5.45833624916467 2.55799711975016 0.0108010607149544 40.3156332381852 12.164269785505 3.31426661436147 0.000980820423978783 CNGA1 other 1 1 1 2.55799711975016 3.31426661436147 1.37704597904415e-08 136.367876870781 32.7413240190425 4.16500801224375 3.64820587173427e-05 -353.206643835369 111.000877581458 -3.18201667888767 0.0015504468830903 MAFK other 0.000105523033374154 1 0.313891633204017 4.16500801224375 -3.18201667888767 0.289887347723406 3.03246731784918 2.98564406795658 1.01568279702029 0.310231143783334 -5.27903164324073 6.50353990940159 -0.811716652281829 0.417308608922968 C1orf228 other 1 1 1 1.01568279702029 -0.811716652281829 2.95149989973393e-06 68.1639507641317 28.0217261818872 2.43253932044315 0.0153129633183245 -381.511615976346 106.351486987447 -3.5872711024847 0.000364118315670597 ZNF43 other 0.0188630358591996 1 1 2.43253932044315 -3.5872711024847 1.29134890148592e-25 272.832358810825 24.4036489560756 11.1799821125889 2.96538389402153e-26 66.4603653976963 75.3553816310924 0.881959111069966 0.378189880757629 GPN1 essential 1.68288588841645e-21 1 4.27845588229426e-22 11.1799821125889 0.881959111069966 0.691032462593201 -5.20094632865013 26.7456791503361 -0.194459310583062 0.845890070426372 -71.5207211317265 84.4018706102271 -0.847383128059015 0.397160519479117 PLN other 1 1 1 -0.194459310583062 -0.847383128059015 0.335681181087443 85.434244895648 64.6446734213005 1.32159759457455 0.186870227009984 -28.7312809596307 132.953123609455 -0.216100834486806 0.828991981692644 C2CD4A other 1 1 1 1.32159759457455 -0.216100834486806 7.07856056460249e-16 128.176719314593 15.2766586253828 8.39036352501992 4.2126247085953e-16 -46.7668893334871 67.0228567695661 -0.697775230534834 0.48561644508377 ZNF28 other 7.52097059989014e-12 1 5.49157757012483e-12 8.39036352501992 -0.697775230534834 1.70820398542604e-05 -217.809305838117 64.2395538417058 -3.39057936757821 0.000748564139829488 -656.733261720346 155.200254776658 -4.2315218017227 2.72803812279863e-05 ITGBL1 other 0.101706465292266 0.320080712947963 1 -3.39057936757821 -4.2315218017227 6.69427494543493e-13 94.1895408710814 16.3074012975923 5.77587680294517 1.30843936223447e-08 -74.7198454547985 32.4944240061915 -2.29946668513224 0.0218678217024693 ZNF511 other 6.36424719062498e-09 1 0.000139440382833328 5.77587680294517 -2.29946668513224 4.38838419070265e-22 83.7825722259472 10.9733641258821 7.63508539995818 1.04769536607604e-13 -193.81136490019 40.1545787138407 -4.8266317592665 1.81527583250468e-06 ZNF627 other 5.41614376816521e-18 0.0227726353187712 1.30406642215484e-09 7.63508539995818 -4.8266317592665 8.69547211770682e-11 2.56328337768323 3.01990901316213 0.848794902929619 0.396372930118305 -29.8522932636516 5.52501740436805 -5.40311298206057 9.85225769684732e-08 KCNRG other 7.51984428739286e-07 0.00130443891906259 1 0.848794902929619 -5.40311298206057 8.18588672741339e-07 90.4732665079234 18.112054755047 4.99519616805004 7.94467515986028e-07 142.873029077647 40.2108723275235 3.55309449429311 0.000413999176395506 WDHD1 essential 0.00551073894489469 1 0.0076936234248087 4.99519616805004 3.55309449429311 7.21663993643346e-12 31.2702552631829 6.30792360750903 4.95729771139878 9.58435165322529e-07 -75.5547754126939 19.9969719284343 -3.77831082041278 0.000175459331574003 ZNF789 other 6.59167891793832e-08 1 0.00922973064205595 4.95729771139878 -3.77831082041278 1.08769340025241e-12 645.961679849352 238.007975235868 2.71403375962171 0.00686056546689659 -3434.25414468138 639.851327917314 -5.36726891832783 1.19113620704982e-07 CTNND1 other 1.02634749247818e-08 0.00157194245244365 1 2.71403375962171 -5.36726891832783 2.07991057977329e-14 442.712688342074 106.846499428791 4.14344588459938 3.96446604985006e-05 -2013.51194606849 378.750227378276 -5.31619996641613 1.5469899941549e-07 DDX39B other 2.0990457571072e-10 0.00203042436732831 0.339913319114144 4.14344588459938 -5.31619996641613 0.458288407079649 8.96671836455107 7.95851093453361 1.12668292326428 0.260388356314062 -23.2186760297514 57.7015747986957 -0.402392414951493 0.687558103685454 ARC other 1 1 1 1.12668292326428 -0.402392414951493 3.41507266159681e-10 26.0328170357334 25.2994989612885 1.02898547815381 0.303942943849058 -551.007078321457 86.6573280374074 -6.3584591263142 4.31449790885361e-10 NUDT16 other 2.86866103574132e-06 6.09250249709218e-06 1 1.02898547815381 -6.3584591263142 7.11187411307602e-11 61.7848977999527 46.8649207451384 1.31836129918905 0.18794060280393 -727.290596193999 117.245888782433 -6.20312237594611 1.100697066955e-09 TLK1 other 6.18164097908567e-07 1.54064568461691e-05 1 1.31836129918905 -6.20312237594611 5.32117305337691e-21 332.393915007087 181.275056406906 1.83364397504843 0.0672601376089179 -3498.85026763659 411.825009598142 -8.49596354298823 1.93970294776919e-16 LRBA other 6.42904128308998e-17 2.94078363911286e-12 1 1.83364397504843 -8.49596354298823 1.97021333677918e-07 0.256241689475227 0.869016686597786 0.294863946144023 0.76821030735208 -8.52581727469585 1.69496273827639 -5.0300912711307 6.66924321680093e-07 C3orf35 other 0.00139431997843863 0.00853596439318351 1 0.294863946144023 -5.0300912711307 2.88320659095955e-06 3.67843688746145 14.978647137195 0.245578713068629 0.80610150246131 -167.233814413949 35.0816445919364 -4.76698901545762 2.40684484181105e-06 MMP17 other 0.018461171801914 0.030049457850011 1 0.245578713068629 -4.76698901545762 2.72708421843883e-15 330.010564468037 39.0825933859699 8.44392697303721 3.00303424125708e-16 179.280844783353 102.238584635482 1.75355366491579 0.0800894415628953 BAZ1A other 2.8418944640351e-11 1 3.92556636017125e-12 8.44392697303721 1.75355366491579 0.808492960066233 0.707282533129198 3.48571676317674 0.202908779221812 0.83928248051151 9.71950365858205 15.1116374746586 0.643180044179932 0.52037929494871 AKR1C4 other 1 1 1 0.202908779221812 0.643180044179932 3.48455790798425e-27 166.287589917499 28.840310925517 5.76580434056184 1.35848234201334e-08 -424.421102884328 55.9701452873102 -7.58299090891505 1.45410581545021e-13 COPS8 other 4.63376510603745e-23 2.1552756396603e-09 0.000144664784601 5.76580434056184 -7.58299090891505 0.000299218338612374 255.281387195961 68.4949475954538 3.72701047533767 0.000213884960578299 -34.8124049836775 160.14677883913 -0.217378115476472 0.827994594984344 CCDC69 other 1 1 1 3.72701047533767 -0.217378115476472 4.57486171118928e-14 156.80747241642 19.4410647125102 8.06578624860579 4.77445160383441e-15 -49.930770558808 158.204304217054 -0.315609431778189 0.75242159598952 MDM4 other 4.55564729200228e-10 1 6.11034316258727e-11 8.06578624860579 -0.315609431778189 0.694583012331424 1.33331683756285 10.1227687486376 0.131714639608092 0.895258974273588 53.0437771119771 62.3981678962953 0.850085489691541 0.395653606298638 RYR2 other 1 1 1 0.131714639608092 0.850085489691541 1.49085673444666e-23 188.483775125435 43.5577691126416 4.32721369723989 1.81271308611567e-05 -749.159660637077 99.0815197148764 -7.56104329841638 1.83199732530048e-13 KLHL9 other 1.88533742638125e-19 2.71227204010737e-09 0.159826912802819 4.32721369723989 -7.56104329841638 0.00212654162573737 13.315245729234 30.9749514994824 0.42987139881257 0.667459102360847 192.782789674157 58.7099411900403 3.2836481482775 0.00109046362830974 FAM3D other 1 1 1 0.42987139881257 3.2836481482775 4.83400371772571e-23 331.321912582861 33.4491823222916 9.90523204395516 2.48003718312608e-21 -491.054848426788 210.197393930795 -2.33616049772939 0.0198554404286988 NCOA6 other 6.0608738612845e-19 1 3.45022772916501e-17 9.90523204395516 -2.33616049772939 0.00699743818037889 32.6694339598242 59.3919665387228 0.550064863377173 0.582501487258861 -443.53336396395 156.518841757159 -2.83373783619034 0.00477214627700314 STK39 other 1 1 1 0.550064863377173 -2.83373783619034 0.0793410265281892 -464.33808125028 741.482951628178 -0.626228937874657 0.531430385499507 -3455.77524912842 1622.56406811864 -2.12982360267313 0.0336393928391072 TAT other 1 1 1 -0.626228937874657 -2.12982360267313 2.74891083372991e-19 299.013502544747 54.574856611172 5.47896084592802 6.54560791372083e-08 -1053.82589306435 185.93867922335 -5.66759911098696 2.34908703574855e-08 C6orf89 other 3.2049551410457e-15 0.000317314676788914 0.00067596492924995 5.47896084592802 -5.66759911098696 0.0551103048554416 4.55632755009131 2.15869536458528 2.11068575253399 0.0352671319260305 -4.04604930112559 6.41427064880157 -0.630788677724652 0.528450611894541 FAM19A2 other 1 1 1 2.11068575253399 -0.630788677724652 1.33271278416355e-18 292.122842074904 63.1342114375953 4.62701339611491 4.64229661464737e-06 -839.774522717918 146.258256841295 -5.74172385788215 1.5594465605159e-08 TTC37 other 1.5262226804241e-14 0.000211959976505321 0.042811259380278 4.62701339611491 -5.74172385788215 2.17046769035081e-28 119.173223903252 13.9430800329362 8.54712327704801 1.38058323885498e-16 -162.420793222109 33.7425970085396 -4.81352378363181 1.94179980637259e-06 TUSC1 other 2.92448816597868e-24 0.024332693373655 1.81436249250321e-12 8.54712327704801 -4.81352378363181 0.665646726939874 -147.697089691189 163.739667923293 -0.902023874632387 0.367451615846815 -95.9628955695901 339.856909953526 -0.282362643686464 0.777775066861428 PAPSS2 other 1 1 1 -0.902023874632387 -0.282362643686464 3.98015323208535e-34 207.231303756619 27.6245002838592 7.50172135702679 2.607952053568e-13 -305.797691873597 51.4324276033714 -5.94562042126031 4.94756709450003e-09 FAN1 other 5.64186720648099e-30 6.82170550989665e-05 3.2176912436922e-09 7.50172135702679 -5.94562042126031 0.404457143046586 13.7465557110593 13.894954391647 0.989319959144523 0.322950522693778 -25.3617108580075 42.1424891967605 -0.601808562840114 0.547554620483201 ABCA4 other 1 1 1 0.989319959144523 -0.601808562840114 1.01237077076279e-20 421.387668622954 42.2039518274725 9.9845547721589 1.13324787732003e-21 311.121093187016 310.040369642783 1.00348575105067 0.316071871478681 IPO9 essential 1.21605976984026e-16 1 1.58156073758784e-17 9.9845547721589 1.00348575105067 6.03062319566941e-16 77.6412239272468 21.9908500503638 3.53061494891883 0.00045077271064769 -365.063942038762 55.0999098412304 -6.62549073293748 8.53546022234599e-11 CEP290 other 6.41778920483138e-12 1.22168042162438e-06 1 3.53061494891883 -6.62549073293748 5.21002104010702e-24 264.212458702403 24.2660946594069 10.8881326975282 4.27960215193634e-25 -29.1446463072917 218.18703806476 -0.133576433163923 0.893787285342142 GLMP other 6.63131477984822e-20 1 6.13438172458555e-21 10.8881326975282 -0.133576433163923 1.18350342605452e-16 24.5331180291164 26.3461769122822 0.931183226727649 0.352186787671334 -481.004976474001 59.4526545547967 -8.0905550824592 4.14736588299654e-15 TOGARAM1 other 1.2874150268621e-12 6.23058776602571e-11 1 0.931183226727649 -8.0905550824592 0.000104082410876467 -19.4179491073474 9.58826468597112 -2.02517866822746 0.0433413697349389 -83.139372990217 19.2555113681294 -4.31769229083287 1.87682449371399e-05 DLL1 other 0.563606254896066 0.222816603893725 1 -2.02517866822746 -4.31769229083287 1.80053452747531e-33 139.535313759112 10.6281970118166 13.1287850238356 5.27044382914606e-34 96.6010270187735 40.2621741761152 2.39929981416852 0.0167944439695657 ANKRD13B other 2.54019411136217e-29 1 7.85506948295929e-30 13.1287850238356 2.39929981416852 7.03825515448606e-10 146.133646473732 51.7248352245261 2.82521241178244 0.00490136481747367 -767.618803062056 158.51997270772 -4.84241064359377 1.68163337357196e-06 ECI2 other 5.80937580451279e-06 0.0211297233389317 1 2.82521241178244 -4.84241064359377 6.21601548568543e-05 68.1294275763559 79.6012975227027 0.855883380003008 0.392444017412024 -816.498110630349 209.64033790763 -3.89475669987761 0.000110694329414697 UNC13B other 0.346977984410961 1 1 0.855883380003008 -3.89475669987761 1.37384413600878e-62 28.0113371771209 1.47695258614932 18.9656306098163 5.36992856465996e-62 7.10320088663119 5.28666295603384 1.34360766814614 0.179633400387126 TEX45 other 2.11640689152153e-58 1 8.3051315181031e-58 18.9656306098163 1.34360766814614 3.28887937586995e-18 121.225183073911 40.4154132706198 2.99947899238818 0.00282822161096703 -592.881198717901 82.3304817849442 -7.20123562821566 1.99633722989581e-12 LDB1 other 3.7302469881117e-14 2.92456420105303e-08 1 2.99947899238818 -7.20123562821566 0.00498853051803934 96.8616872041538 29.6444413193656 3.26744856348086 0.00115341348268256 112.811516992554 73.5042235782107 1.53476237828047 0.125421440066596 PPP1R14C other 1 1 1 3.26744856348086 1.53476237828047 2.11507466518403e-25 328.641608799054 58.3734229121888 5.6299869427467 2.90293638545269e-08 -822.751422345354 123.893287919472 -6.64080707003371 7.63204639489999e-11 CTR9 essential 2.74811651247361e-21 1.09283272328573e-06 0.000304808320472532 5.6299869427467 -6.64080707003371 0.000112077862635939 16.9188252761306 54.6358287225789 0.309665391222274 0.756935103389567 423.118671783858 106.750771379227 3.96361231227782 8.37675831206806e-05 SMOC1 other 0.604996302508798 0.949338019506674 1 0.309665391222274 3.96361231227782 0.320802242285847 8.96446178478413 6.41779861746279 1.39681257065186 0.163038450806026 32.5617864473905 48.2772316642593 0.674475012855733 0.500295360119907 F5 other 1 1 1 1.39681257065186 0.674475012855733 4.58114692395766e-18 149.439770604733 19.86722519383 7.52192463450521 2.25658384075921e-13 -239.068196856986 90.8635659872289 -2.63106773611094 0.00875396362650413 MSRB1 other 5.17623790937976e-14 1 2.788009335258e-09 7.52192463450521 -2.63106773611094 4.82813356613432e-49 428.708590433978 31.593803861808 13.5693882354008 4.10432981953366e-36 -1070.80414590431 156.665623595769 -6.83496558675318 2.30873742323512e-11 ZNF652 other 7.28130823108717e-45 3.3347403341208e-07 6.15033823457119e-32 13.5693882354008 -6.83496558675318 1.31005748547363e-11 138.146811093076 24.6414276259421 5.60628276860215 3.2935053564451e-08 -214.574474067519 77.5854328202989 -2.76565414753193 0.00587421622067752 SMURF1 other 1.18009978291465e-07 1 0.000344830010819802 5.60628276860215 -2.76565414753193 2.62312255451615e-09 270.639160642762 42.3012018629661 6.39790712139792 3.43242697917338e-10 133.186159023232 128.324721528236 1.03788387332621 0.299791227579567 SLC5A3 other 2.10033422940108e-05 1 3.89134246628886e-06 6.39790712139792 1.03788387332621 2.28060147608568e-13 19.6374140077363 11.2676847920721 1.74280824944209 0.0819321577238432 -96.6912820896021 17.4756828376574 -5.53290437849143 4.90127525424627e-08 GPATCH3 other 2.21286761224593e-09 0.000655398526997811 1 1.74280824944209 -5.53290437849143 2.01120982206314e-25 391.844056893821 82.89206932216 4.72715978860316 2.90870296339192e-06 -1324.58255972459 174.637820244956 -7.58474056688673 1.46584069511377e-13 CDC42BPB other 2.61417052671766e-21 2.1723759101586e-09 0.0272050988166047 4.72715978860316 -7.58474056688673 2.12981972946023e-05 131.937604360597 253.99480253646 0.51945001646897 0.603657463161233 -3571.8027944648 846.71653351417 -4.21841626221773 2.88031547742381e-05 RPL10A essential 0.125488978459797 0.337486564489748 1 0.51945001646897 -4.21841626221773 0.53271617670824 -1.44823953119656 3.98619459864895 -0.363313806026282 0.716512136795663 29.3279177089412 28.3629677771809 1.03402147262377 0.301587266583238 COLGALT2 other 1 1 1 -0.363313806026282 1.03402147262377 0.288585166135654 -1.95945144409732 11.8319600485363 -0.165606665003887 0.868529414312749 175.745817454537 112.751646555783 1.55869845650181 0.119662421735771 APCDD1L other 1 1 1 -0.165606665003887 1.55869845650181 0.795327328925609 0.923811814562939 17.1863534517644 0.0537526367740387 0.957152161919352 -94.6432798071118 140.884813620806 -0.671777726603278 0.502013033749024 RCSD1 other 1 1 1 0.0537526367740387 -0.671777726603278 0.0212716225820653 -2.47046028655501 6.30325573883623 -0.391934008219558 0.695264519116906 39.4059861925972 15.5106980178811 2.54056820313109 0.0113514102380959 RASSF9 other 1 1 1 -0.391934008219558 2.54056820313109 2.88072986161325e-05 0.899536811827105 15.23518592861 0.0590433760403196 0.952939162220418 -151.133677237001 35.7220080020222 -4.23082815580931 2.7306534277023e-05 FAM169A other 0.167428019556962 0.320360260138034 1 0.0590433760403196 -4.23082815580931 1.38018428646278e-47 89.9218707245006 8.08214147813593 11.1259956247685 5.38079535990466e-26 -117.882249599105 18.9821972020206 -6.21014776869752 1.06757127336214e-09 ZNF830 essential 2.0748310378395e-43 1.49470653983434e-05 7.75103571594266e-22 11.1259956247685 -6.21014776869752 0.00221273323524026 3.48891315550404 1.14093699533478 3.05793673951321 0.00233807722474367 -1.51735540540241 2.41136274196951 -0.629252239405129 0.529447602839652 GRIN3A other 1 1 1 3.05793673951321 -0.629252239405129 1.93975398057751e-56 437.433854637595 53.5980102487483 8.16138234623758 2.37640167072711e-15 -817.269395893748 109.265944315166 -7.47963513257544 3.06739024837168e-13 CNOT7 other 2.96588383630302e-52 4.53084213586981e-09 3.05676546905628e-11 8.16138234623758 -7.47963513257544 3.89595484699263e-42 559.315274137312 56.9777852996197 9.81637442024348 4.80541189663217e-21 -663.456766382451 117.505343328696 -5.64618380397029 2.64948210890942e-08 TMEM184B other 5.75783166837041e-38 0.000357335652028613 6.67279495966343e-17 9.81637442024348 -5.64618380397029 3.18677434810206e-13 211.975148374466 58.6725202736237 3.61285227540771 0.000330917825776696 -394.231749894168 95.0202421513619 -4.14892386051994 3.87569827573205e-05 MTOR essential 3.07364385874443e-09 0.450162354726278 1 3.61285227540771 -4.14892386051994 4.34792871801304e-08 210.83582973134 39.0133398512127 5.40419842380621 9.79584706702223e-08 -58.3870551406785 75.0352262939954 -0.778128594054108 0.436835273093832 SCAMP5 other 0.000322659790163748 1 0.00100123352872034 5.40419842380621 -0.778128594054108 2.10582496159838e-06 257.674126779548 49.8673763616934 5.16718836199864 3.37308615542712e-07 193.439752518564 113.251048121147 1.70806147693782 0.0882115985334748 ZNF521 other 0.0136604865258887 1 0.00334508954033707 5.16718836199864 1.70806147693782 0.0875871191543094 3.87752534618974 11.1244356475393 0.348559285975774 0.727555549058567 51.9970410468034 24.4074036138372 2.13037985807408 0.0335899075028057 ALPK2 other 1 1 1 0.348559285975774 2.13037985807408 0.569578750170315 -3.9551918101327 25.9135120294002 -0.152630481180834 0.878746698320652 -194.783667960173 184.043866236393 -1.05835457569656 0.290367013864002 BRINP2 other 1 1 1 -0.152630481180834 -1.05835457569656 5.80957257758818e-11 42.9877978113599 17.8053288761698 2.4143220330456 0.0160947886811387 -203.639091193329 40.3161180380804 -5.05105900823543 6.01318387222645e-07 LRIG2 other 5.07175686023448e-07 0.00771190831613042 1 2.4143220330456 -5.05105900823543 1.09597972366138e-15 325.099004884724 38.2924605240331 8.48989593344847 1.961848225603e-16 415.088997368707 106.884848239402 3.88351580421377 0.000115573467213507 PNP other 1.15713539224169e-11 1 2.57257157823322e-12 8.48989593344847 3.88351580421377 2.18012388397092e-06 -5.05360856208082 17.0690292848569 -0.296068890488355 0.767292143153825 -218.075427020074 43.6001563839279 -5.00171203744722 7.71336119241834e-07 PAX9 other 0.0141228425203636 0.00984919090659897 1 -0.296068890488355 -5.00171203744722 1.89768326029424e-14 241.969485308208 41.229157619675 5.86889229074952 7.66891661185144e-09 -357.645060477725 98.3609670158862 -3.63604660800012 0.000303412510802081 FOXJ3 other 1.91817823950542e-10 1 8.24791981604622e-05 5.86889229074952 -3.63604660800012 2.4740242283053e-35 502.527459769456 40.3523987057347 12.453471810538 1.64256136427598e-31 -295.085874762201 144.450461805052 -2.04281710888847 0.0415502247065049 ZNF358 other 3.53958646343639e-31 1 2.42786995253633e-27 12.453471810538 -2.04281710888847 7.28937606060325e-45 203.152586223054 19.8758088334294 10.2210978142117 1.49636863992983e-22 -228.512197548131 41.5030445144267 -5.50591408947597 5.66846991813777e-08 SFT2D1 other 1.08793937704503e-40 0.000756343941177123 2.10404394460533e-18 10.2210978142117 -5.50591408947597 0.554486786008722 -2.23908679049355 4.11594890440919 -0.54400257206666 0.586665070036245 30.9650214146757 33.9977955273263 0.910794977568091 0.362811295991154 CD247 other 1 1 1 -0.54400257206666 0.910794977568091 6.52264740787782e-31 226.494937248147 20.3229628687747 11.1447793666024 4.53518729452389e-26 -80.3260435497442 47.3377818106948 -1.69686961402143 0.0903062345692623 CHAMP1 other 9.00125342287139e-27 1 6.53565841013838e-22 11.1447793666024 -1.69686961402143 0.0441591432814029 52.4294102929493 24.1004718652783 2.1754516088328 0.0300293021540988 -14.1048133306705 44.7547729492456 -0.315157745223423 0.75276363476064 INPP5F other 1 1 1 2.1754516088328 -0.315157745223423 2.54613384358047e-07 216.741495128333 38.8148302497288 5.58398668070556 3.71294654807279e-08 214.873971775216 73.5365550060207 2.92200214923889 0.00362214816882718 ARHGAP11A other 0.00178713134480913 1 0.000387817266946203 5.58398668070556 2.92200214923889 0.616179904138331 -0.580659038444575 4.91170738728017 -0.118219387406568 0.905937466428739 20.5190093498244 21.1555392307198 0.969911904681158 0.332521434220517 SUCNR1 other 1 1 1 -0.118219387406568 0.969911904681158 1.16844620098942e-18 1334.90748467662 180.222887176714 7.40698090896581 4.94484900068418e-13 -369.463513077591 296.169802295258 -1.24747192392445 0.212760270521641 HMGN2 essential 1.33962356943437e-14 1 6.05249517683744e-09 7.40698090896581 -1.24747192392445 0.000537157381473181 7.62998398691097 125.485111142802 0.060803898704987 0.951537881934754 -885.814785289819 259.119420052858 -3.41855807298858 0.000677057329835768 SELENOM other 1 1 1 0.060803898704987 -3.41855807298858 2.85283031952849e-24 257.417870016081 45.8177897955219 5.61829523346497 3.08688028079305e-08 -511.48604046615 104.678530370096 -4.8862554590494 1.35528124349035e-06 UBE2J1 other 3.64591714835741e-20 0.0171117809803092 0.000323690266243959 5.61829523346497 -4.8862554590494 0.0463843449243349 0.923409334079561 1.17638662232487 0.784953956935216 0.432843613384501 -16.3495488148444 7.17941384313902 -2.27728184668847 0.0231809778407258 GJC2 other 1 1 1 0.784953956935216 -2.27728184668847 4.7797197250913e-36 519.110619150846 37.7189857914882 13.7625815821376 3.28625172828986e-37 -135.700701231854 176.705603852391 -0.767947921703774 0.442850113839657 OPA1 essential 6.8684572449562e-32 1 4.93595009589137e-33 13.7625815821376 -0.767947921703774 8.16404802748809e-19 136.323527281026 14.6428005716528 9.30993539206813 3.27041076799176e-19 183.399342922655 151.096654207477 1.21378824623622 0.22536315361759 DENND4B other 9.3935536604278e-15 1 4.45789691784957e-15 9.30993539206813 1.21378824623622 0.142966018709074 14.3980640570703 8.40148650975128 1.71375197000662 0.0871450032783013 26.2993740174009 15.4691087348427 1.700122125211 0.0896805940757846 RYR3 other 1 1 1 1.71375197000662 1.700122125211 1.92574557300637e-09 38.7787018275055 10.025623209449 3.86795922980201 0.000123218054472837 -116.296570281665 31.3853724714815 -3.70543858886296 0.000232900068460016 ZNF277 other 1.55542469931724e-05 1 1 3.86795922980201 -3.70543858886296 1.78037735531357e-15 44.2350268681433 6.74853908472517 6.55475597203936 1.3055433778104e-10 -39.1382383487882 13.5870417523417 -2.88055627282096 0.00412771860752423 KTI12 essential 1.86654761931075e-11 1 1.49915546073968e-06 6.55475597203936 -2.88055627282096 0.938339850350871 0.28131475866562 6.69395737907323 0.0420251792377811 0.966494188332646 -19.5675936661514 55.4932700345145 -0.352612013204146 0.724517169682414 DUSP27 other 1 1 1 0.0420251792377811 -0.352612013204146 4.13386137175616e-06 156.636644731307 63.3488240497611 2.4726054047707 0.0137178367034645 -1155.38470240545 274.312826049463 -4.21192373336971 2.96335674336903e-05 SELENOT other 0.0260143896124615 0.346890540378779 1 2.4726054047707 -4.21192373336971 0.00751969148903345 -55.7197392388798 21.6717295615957 -2.57107948308935 0.0104028391934016 -106.084519331578 38.5602057899761 -2.75113986448576 0.00613674713065682 ARHGEF15 other 1 1 1 -2.57107948308935 -2.75113986448576 0.845230755021027 1.24382765954347 4.45468885213451 0.279217629071328 0.78019034514154 20.3587328293201 37.8210652772426 0.538290835545825 0.590609747629706 TOX other 1 1 1 0.279217629071328 0.538290835545825 0.0753083043732743 181.748377506108 96.1415018014007 1.89042582132267 0.0592322598889889 471.48605517601 216.952554396768 2.1732219585382 0.0301943482643547 CES1 other 1 1 1 1.89042582132267 2.1732219585382 0.455529060946821 -9.90712449963648 26.9695767051844 -0.367344456605135 0.713504435035234 -59.3468373153481 49.7049675222805 -1.19398201575618 0.233003475234017 CD3E other 1 1 1 -0.367344456605135 -1.19398201575618 8.27157906220244e-05 62.9559381148275 23.8724457400562 2.63718006945522 0.00860247750305708 -159.267595881136 62.9876591650259 -2.52855238617234 0.0117392866005462 RUSC2 other 0.45477141683989 1 1 2.63718006945522 -2.52855238617234 4.54594328295488e-09 31.2032792506208 9.44088376588319 3.30512270084089 0.0010115396196554 -89.5955425837945 21.8031249801157 -4.10929821598991 4.576884979514e-05 FICD other 3.59220438219095e-05 0.52954559212977 1 3.30512270084089 -4.10929821598991 3.17917706803555e-11 256.722678075414 46.7985473847182 5.4856975787083 6.32797266320956e-08 -194.834897295164 101.854144925954 -1.91288137990658 0.0562899025035745 OSTC essential 2.81293586979786e-07 1 0.000653869415289444 5.4856975787083 -1.91288137990658 7.29346135814302e-18 213.022269623036 64.0101193043693 3.32794676744955 0.000936112996815454 -673.838158682061 114.403085475382 -5.89003483500508 6.89351669529332e-09 R3HDM4 other 8.20806141245415e-14 9.46824518098537e-05 1 3.32794676744955 -5.89003483500508 2.04345372085829e-20 142.499668345368 14.3908435968213 9.9021066684961 2.32989905720435e-21 154.335382040027 102.395159875394 1.50725270831004 0.132328508688737 TSEN15 other 2.43906636121645e-16 1 3.2425205179113e-17 9.9021066684961 1.50725270831004 2.02354780777779e-08 143.883395380828 33.5867556540168 4.28393253766444 2.18426479637414e-05 -270.486256102103 94.5458528059585 -2.86090027298433 0.00439274956854752 LTN1 other 0.000153789633391112 1 0.191581865289976 4.28393253766444 -2.86090027298433 2.3956467498834e-64 183.39883421914 32.9559799349688 5.56496376624322 4.15085563800232e-08 -1095.7261747684 72.6156200721872 -15.0894005129907 4.02451717099986e-43 RUNDC1 other 3.69696206442006e-60 6.31044292412778e-39 0.000432560666036221 5.56496376624322 -15.0894005129907 0.00218673715123616 605.441350854995 313.042094442915 1.93405730923322 0.0536452117861202 -3860.45006990398 1475.69253745424 -2.61602601620779 0.00915306627531915 CCDC152 other 1 1 1 1.93405730923322 -2.61602601620779 7.28258364564935e-09 3.25891602449593 1.29554083613085 2.515486917594 0.0121716774056635 -13.7248634379858 3.09540241072759 -4.43395126605195 1.11828311217706e-05 STKLD1 other 5.68696956888757e-05 0.134618921043875 1 2.515486917594 -4.43395126605195 0.0551982589222514 -0.77451245339826 17.047235420464 -0.0454333171505633 0.963778721200861 -71.1233373883691 31.6568553064053 -2.24669622740381 0.0250626488803312 GRK5 other 1 1 1 -0.0454333171505633 -2.24669622740381 1.76655613382059e-12 54.3774889809882 13.3595124976044 4.07031985566383 5.41499782471462e-05 -263.844823985091 49.1407803094187 -5.36916227873817 1.18799307746564e-07 TYW1 other 1.65431871482094e-08 0.00156791326363916 0.45881276568807 4.07031985566383 -5.36916227873817 7.91245324152056e-33 467.87806200543 45.0075001491356 10.3955576393953 3.27814254520502e-23 -461.021067273698 117.515887512405 -3.92305310399015 9.86299537792067e-05 DCAF12 other 1.11130405777156e-28 1 4.63824388721058e-19 10.3955576393953 -3.92305310399015 0.00252297992098926 66.349915911722 19.3654916399661 3.42619320724038 0.000658527631761569 -5.66205425589886 83.0390302711264 -0.0681854573374951 0.945663149843188 SFMBT2 other 1 1 1 3.42619320724038 -0.0681854573374951 0.415323637803892 2.37924878890661 5.85852081571151 0.406117664125368 0.684824510747845 -26.0324426030295 22.1973224501556 -1.17277399837236 0.241427564574761 ITPRIPL1 other 1 1 1 0.406117664125368 -1.17277399837236 1.64311336926524e-12 266.332747101633 40.4488469236753 6.58443360830998 1.08063952790557e-10 -131.182704930238 91.1177981684197 -1.4397045096257 0.150528324992371 SMC5 essential 1.53992584967539e-08 1 1.2439241605721e-06 6.58443360830998 -1.4397045096257 1.80561607880636e-13 108.148738092984 19.2611629598 5.61486024071866 3.18050486246269e-08 -103.373568815095 39.7834547368653 -2.59840603333285 0.00962692424227924 PRMT6 other 1.75848949914952e-09 1 0.000333285104537465 5.61486024071866 -2.59840603333285 3.42353731288469e-06 47.2408148056016 9.52325211859288 4.96057588493013 9.40626281202635e-07 -64.221090349539 69.6365569834568 -0.922232418308614 0.356815433190498 SHISA4 other 0.0217462393850842 1 0.0090666967245122 4.96057588493013 -0.922232418308614 2.7358023527536e-22 5.90058972292502 41.3202658958777 0.142801349289325 0.886499946507449 -815.791141290656 86.8823728767238 -9.38960475271746 1.63685881683107e-19 CIPC other 3.38883837435589e-18 2.51699780264113e-15 1 0.142801349289325 -9.38960475271746 2.47358431335695e-15 222.827138346733 46.968828884346 4.74414933562453 2.68392164077262e-06 -739.47913906517 144.786523464537 -5.10737547508208 4.53681675640456e-07 CAPZA2 other 2.58118523098798e-11 0.00584750311732983 0.0251483457740395 4.74414933562453 -5.10737547508208 2.82101178059142e-15 393.074638784253 49.4665918319616 7.94626482696707 1.1732150777722e-14 -484.550009574774 301.475922202064 -1.60725939914367 0.108596410333621 TOP1 essential 2.93864797184209e-11 1 1.49127368535625e-10 7.94626482696707 -1.60725939914367 4.79462845535792e-23 795.586382141311 78.7459586462464 10.1032027016822 4.34921148423272e-22 1169.26275625246 201.088582700574 5.81466506228013 1.04361730216044e-08 PRC1 essential 6.0134230087099e-19 0.000142589431994181 6.08933099907424e-18 10.1032027016822 5.81466506228013 2.49700366626042e-30 129.523791370994 10.7936043207447 12.0000499853471 1.75985980858779e-29 -58.5419031087913 49.6935177110945 -1.17805914745539 0.239307755368738 MAP3K3 other 3.42663813120918e-26 1 2.5811863812557e-25 12.0000499853471 -1.17805914745539 1.96630944940906e-41 1198.1595837807 137.891178330929 8.68916777913957 4.2932110661355e-17 -1647.7238853765 258.886650526657 -6.36465372789406 4.16099432669931e-10 SREBF2 other 2.89676708086942e-37 5.87906888419345e-06 5.69623244254858e-13 8.68916777913957 -6.36465372789406 1.4977446599267e-17 95.7713801731286 13.3164750220591 7.19194681884512 2.13327719321259e-12 -32.2497019913743 22.3448051408289 -1.44327515000106 0.149520676185249 C1orf174 other 1.67028484475026e-13 1 2.57507889992692e-08 7.19194681884512 -1.44327515000106 0.00265590428997441 69.4711205138664 20.9864356133862 3.31028678684026 0.000996675382738964 -4.66190864600345 60.4798603146809 -0.0770820008800817 0.9385879604162 RASGEF1A other 1 1 1 3.31028678684026 -0.0770820008800817 7.49627023999141e-15 117.840616566501 32.8443092609306 3.58785491971592 0.000363492635641079 -422.450817887297 72.562152126375 -5.82191687412402 9.95183351709603e-09 SPOUT1 other 7.70016879051917e-11 0.000136081371512771 1 3.58785491971592 -5.82191687412402 0.00457112006378766 46.5780283947794 31.6437823203398 1.471948830998 0.141616160927618 -296.132004965945 108.222547850791 -2.73632446146277 0.00641713806745051 DZIP3 other 1 1 1 1.471948830998 -2.73632446146277 4.1367655240937e-57 72.9952126639498 12.9896655794993 5.6194835977266 3.05923725712816e-08 -326.209696728126 23.9093947869914 -13.6435781680936 1.13514514401023e-36 KIAA0753 other 6.33214698773023e-53 1.77899946969283e-32 0.000320883395900173 5.6194835977266 -13.6435781680936 3.84777253059255e-09 94.7413049131639 16.8942543082181 5.60790095761005 3.25648830351999e-08 -17.4528511830493 32.0829733991217 -0.543991074827471 0.58666967523722 DCLRE1A other 3.05359228027825e-05 1 0.000341052020027649 5.60790095761005 -0.543991074827471 4.88113043446768e-10 330.213543272083 54.5402820525909 6.05448910135214 2.63602934483329e-09 -133.3837109449 122.261924963033 -1.09096688102392 0.275773100274628 ATG9A other 4.06598165191158e-06 1 2.88355250031314e-05 6.05448910135214 -1.09096688102392 0.469927045635756 5.57200475356365 8.56182573798969 0.65079632826911 0.515455296386579 89.3593415223058 88.9102921137538 1.0050505897335 0.315323467239924 NOS1AP other 1 1 1 0.65079632826911 1.0050505897335 1.07091438032461e-28 448.62157254593 88.7928324631742 5.05245254713538 6.00571701460747e-07 -1022.4435548768 190.848132452395 -5.35736735664332 1.2592834762322e-07 APRT other 1.44723369357067e-24 0.0016589800515883 0.00585557408924228 5.05245254713538 -5.35736735664332 4.73010734559211e-06 0.36239042116338 8.86837739487436 0.0408632160120779 0.967420359879636 -115.135053032105 24.3321070259945 -4.73181598737436 2.85955078715345e-06 TBKBP1 other 0.029605741876061 0.0355613735890403 1 0.0408632160120779 -4.73181598737436 8.09729998213267e-14 131.422416218178 16.5613917173851 7.93546934103483 1.20704098799537e-14 96.8338052421716 56.2103585946677 1.72270392260685 0.0855114458875545 CCDC167 other 7.99365454236138e-10 1 1.53366627934692e-10 7.93546934103483 1.72270392260685 2.30720406658822e-16 4.45605790444751 2.2113553764735 2.01507996039682 0.0443894919427984 -44.0080298290545 5.99231067386125 -7.34408348035419 7.64741363660041e-13 ZFP2 other 2.48855030622205e-12 1.12462864939846e-08 1 2.01507996039682 -7.34408348035419 9.64408394344246e-05 -20.2492040471195 30.876132282773 -0.655820614501555 0.512222534989465 -302.483210902322 72.0172415423345 -4.20014991444112 3.12642033672909e-05 SOWAHA other 0.524877173836673 0.365259687940059 1 -0.655820614501555 -4.20014991444112 0.204559839969163 1.24843499462266 8.06305144137185 0.154834060491898 0.877009779166169 -29.2171064977909 19.2137857863391 -1.52063246789001 0.128935234097402 L3MBTL3 other 1 1 1 0.154834060491898 -1.52063246789001 7.32784863599357e-06 148.938961055244 35.586897637407 4.18521902563059 3.32645911481078e-05 308.699869030041 75.2695424520598 4.10125874256052 4.7436778257198e-05 MFAP3L other 0.0450809248086324 0.548321719874952 0.287339538337355 4.18521902563059 4.10125874256052 8.60223971469617e-31 183.724381114677 28.8625570624691 6.36549217441233 4.13443130096077e-10 -362.824363464192 56.2141269562288 -6.45432710796532 2.40502799671459e-10 NAGA other 1.1849585206994e-26 3.41417774413603e-06 4.67356114260605e-06 6.36549217441233 -6.45432710796532 1.38784492246845e-14 419.873134195767 52.9259044380721 7.93322549049784 1.24542019594241e-14 1082.47751034906 475.746373133313 2.27532477698096 0.0232789305710126 SMG5 essential 1.41005044122794e-10 1 1.58218181692523e-10 7.93322549049784 2.27532477698096 5.27285131171326e-24 153.217174348284 22.6523047740903 6.76386689461875 3.47222387128801e-11 -371.434924117267 60.903590127546 -6.09873610635099 2.02705823449801e-09 KIF1BP other 6.71023057928629e-20 2.82065153330398e-05 4.05312692495449e-07 6.76386689461875 -6.09873610635099 0.620742622813354 100.43395403426 113.476331304245 0.885065219151156 0.376518318885123 -231.256694240852 792.584969877749 -0.291775270828718 0.770571343029547 TGM2 other 1 1 1 0.885065219151156 -0.291775270828718 1.18097260686394e-20 303.149895261286 104.362152743799 2.90478767724823 0.00382417334870849 -1776.12290492636 231.252975201909 -7.68043266632837 7.40029479464985e-14 PJA2 other 1.41610425289055e-16 1.10034983301649e-09 1 2.90478767724823 -7.68043266632837 0.0460361206400107 -1.56601493771239 4.42826493918105 -0.353640750772696 0.723744889376309 -23.7999130871038 9.73220337568319 -2.44548044963488 0.0147812836526246 RORB other 1 1 1 -0.353640750772696 -2.44548044963488 0.000127430786592817 67.4054930452639 29.1472926931531 2.31258160937526 0.0211242392442418 -207.822923729776 77.3490116126852 -2.6868206767841 0.00743793457425003 SGMS1 other 0.684558185576615 1 1 2.31258160937526 -2.6868206767841 0.0316389976997797 5.12902751919971 3.48949404417017 1.46984848068982 0.142183017901294 -7.56224896436695 6.6702598416869 -1.13372629310562 0.257410585227485 SNORA31 other 1 1 1 1.46984848068982 -1.13372629310562 8.23412202367783e-10 3.36905498599056 0.586604934033375 5.74331170865821 1.54019222717657e-08 -1.3857239885172 1.39842571461193 -0.990917124905517 0.322163374993675 SNORD36A other 6.76844830346318e-06 1 0.000163676227982054 5.74331170865821 -0.990917124905517 9.6925438814092e-11 4.58239148470558 0.764116397712104 5.99698095529169 3.76534352487639e-09 -8.2937112965004 3.56621477302569 -2.32563427173057 0.0204217915572591 SNORD104 other 8.35788058893915e-07 1 4.09594068636054e-05 5.99698095529169 -2.32563427173057 0.816395550802479 -9.77930817173415 18.0761712201519 -0.541005506787403 0.588726472842777 -25.7105686193877 74.604030420126 -0.344627072754661 0.730508678226225 SNORA63 other 1 1 1 -0.541005506787403 -0.344627072754661 0.730390337512362 -56.7014016047743 90.543830939587 -0.626231528049733 0.531425759665154 -132.63044941707 203.837382615036 -0.650667937919677 0.515535578378373 RNU4-1 other 1 1 1 -0.626231528049733 -0.650667937919677 0.511965803565594 2735.12667691895 2558.75539258792 1.06892854426099 0.2855930962268 -868.152146096815 9466.61936316465 -0.0917066708602295 0.926966077842317 RN7SK other 1 1 1 1.06892854426099 -0.0917066708602295 0.727963505924867 -338.317626076992 539.621691425173 -0.626953347971383 0.530952839873649 -797.535678461237 1214.8268086403 -0.656501546384113 0.51177907386538 RNU4-2 other 1 1 1 -0.626953347971383 -0.656501546384113 5.73356970418667e-09 69.6228458868582 11.5188124720839 6.04427288451747 2.79117639692854e-09 -26.4468506384037 48.3260109226344 -0.547259128851804 0.584425563883063 ZNF525 other 4.50429235960905e-05 1 3.0504766842032e-05 6.04427288451747 -0.547259128851804 2.81246362829034e-10 385.534681858601 96.4328690908989 3.99795925904881 7.28676863772546e-05 -693.948724843438 201.084630462079 -3.45102817280859 0.000602580727011398 INF2 other 2.37259431682573e-06 1 0.609611064232112 3.99795925904881 -3.45102817280859 1.53456756192134e-09 81.4258990155512 15.3111883396017 5.31806527419865 1.54250009058975e-07 -13.7001238180147 31.3209173206168 -0.437411320932056 0.661989261382493 GP1BB other 1.24438083596201e-05 1 0.00155715384145035 5.31806527419865 -0.437411320932056 0.0236106139958944 4.91048034592297 5.81255340301235 0.844806061201626 0.398591194174134 -93.528936820338 36.3973170686858 -2.56966568837584 0.0104453539807289 EFCAB2 other 1 1 1 0.844806061201626 -2.56966568837584 2.11555169421103e-16 277.507894400971 33.1674343225821 8.36687853820606 5.02657182761412e-16 -471.889118316538 208.028656783104 -2.26838516199497 0.0236975389756073 COX20 other 2.2837380539008e-12 1 6.54359120518806e-12 8.36687853820606 -2.26838516199497 4.91475189972473e-10 233.447695389937 35.0948622283944 6.65190516693525 7.07387028905976e-11 238.339418387211 215.807650687055 1.10440671416617 0.269905894390037 CHML other 4.09300538209075e-06 1 8.18093098929761e-07 6.65190516693525 1.10440671416617 0.924452612180213 15.7619207942726 40.4620777310694 0.389547983646167 0.697024120041371 -11.3686025993815 257.177647633814 -0.0442052515215818 0.964757106995778 STUM other 1 1 1 0.389547983646167 -0.0442052515215818 0.00885796225334234 53.1457406037779 51.6017423929313 1.0299214355804 0.303511401907462 -896.95913588283 320.797010949809 -2.79603333343765 0.00535904512168133 CAPN8 other 1 1 1 1.0299214355804 -2.79603333343765 1.06975271060547e-21 54.4043376582292 5.5408262935392 9.81881307516653 4.92910840670794e-21 -61.4054373703186 34.3577557414383 -1.78723656552045 0.0744652434452184 TATDN3 other 1.31034009522064e-17 1 6.84406702271398e-17 9.81881307516653 -1.78723656552045 0.00184404531460167 4.16608877886682 1.70640594347489 2.44144061663491 0.0149536169440612 31.7899679391017 11.5416964357165 2.75435834897942 0.00608202651708308 SERTAD4-AS1 other 1 1 1 2.44144061663491 2.75435834897942 0.420158192014987 -1.63614972254544 1.70036922681332 -0.962232023930331 0.336374357689289 12.0304030923828 13.5256173289515 0.889453161345314 0.374165410240228 CR1 other 1 1 1 -0.962232023930331 0.889453161345314 0.214320195778293 1.68814595665945 1.05940804020154 1.59348040849143 0.111635426005828 -5.07636497612066 7.69861008522424 -0.659387203654281 0.509927216930557 LINC00862 other 1 1 1 1.59348040849143 -0.659387203654281 0.0020989699197724 5.38195844679208 1.65628511274294 3.24941545714862 0.00122772517288965 0.496929466291069 4.12581789902296 0.120443867968276 0.904175931379006 RAET1G other 1 1 1 3.24941545714862 0.120443867968276 0.539982472828996 1.45918025634177 1.40220909415757 1.04062957687379 0.298519300638524 -3.32711985822675 9.88507149086794 -0.336580252484812 0.736565820634502 C1orf53 other 1 1 1 1.04062957687379 -0.336580252484812 0.174940285428408 -32.4457900565161 19.2386510604002 -1.68648986639717 0.0922758823621055 -62.3600596022779 41.3160685488168 -1.5093415659478 0.131793152569497 SAMD5 other 1 1 1 -1.68648986639717 -1.5093415659478 0.00541775383814674 -0.360995630843035 1.65961673897206 -0.217517467958675 0.82788992894766 -11.1764569535523 3.76197166717235 -2.97090407433955 0.00310576519615179 ECT2L other 1 1 1 -0.217517467958675 -2.97090407433955 0.207190533671162 17.2185147787773 49.2710349651432 0.349465254605642 0.726877051246855 965.999895355243 557.783930046959 1.73185322007021 0.0838739592568159 FCGR3A other 1 1 1 0.349465254605642 1.73185322007021 1.5534840802432e-13 178.625847847994 24.8306001141054 7.19377892709581 2.12517150584617e-12 27.5710099060476 56.8954357710859 0.484590890857701 0.628163802451731 CENPW essential 1.5177539463976e-09 1 2.56550704185749e-08 7.19377892709581 0.484590890857701 0.00103902716310758 17.9054628375688 7.9853147421263 2.24229894697939 0.0253587220789697 -28.9906771263638 15.8709278562966 -1.8266529461201 0.0683196346746686 SPRN other 1 1 1 2.24229894697939 -1.8266529461201 1.03093130807857e-14 18.1954009287565 5.29885275879773 3.43383780546581 0.000640966364795359 -80.576163806982 15.1535707517808 -5.31730541446893 1.54648372940891e-07 FAM229B other 1.05185719632054e-10 0.00202991454322214 1 3.43383780546581 -5.31730541446893 1.22190180417182e-15 7.82945260321635 12.0339328750216 0.650614614900144 0.515572528641802 -176.247441012184 23.0494354211712 -7.64649709598951 9.54385421118395e-14 FANK1 other 1.28825107213835e-11 1.4179304201556e-09 1 0.650614614900144 -7.64649709598951 0.342854727320127 -0.790359542104537 0.579219647257339 -1.36452474609065 0.172966639454772 -3.16222857595609 6.74454504926763 -0.468857210213084 0.639359533554119 SPRR2E other 1 1 1 -1.36452474609065 -0.468857210213084 1.30753609011146e-08 42.8219244880254 13.908407399324 3.07885175193436 0.00218382171547882 -101.173703738767 26.6986184676758 -3.78947337148769 0.000167988349980293 EEF1AKMT2 other 0.000100340319555153 1 1 3.07885175193436 -3.78947337148769 5.00316320494428e-05 -2.18265753769554 3.61972408017774 -0.602990031656878 0.546768947564416 -43.8538034568874 10.2825601634391 -4.26487205130243 2.36219630426595e-05 DDO other 0.28277878434345 0.278361212494699 1 -0.602990031656878 -4.26487205130243 0.00334991324669111 10.6066726344568 3.89713245285833 2.72166080130979 0.00670877259870787 -4.09008540391456 9.61464458172961 -0.425401622404932 0.670716271787634 CCDC162P other 1 1 1 2.72166080130979 -0.425401622404932 2.00405255834691e-06 19.4215375166343 3.74519174482939 5.18572581589384 3.09344650891919e-07 -9.03107129010862 44.2471941637683 -0.204104948591377 0.838351805527099 ADAMTSL4-AS1 other 0.0130363618920466 1 0.00307426714056389 5.18572581589384 -0.204104948591377 0.245913900491644 -7.27034850595138 14.3197900277601 -0.5077133457863 0.611862461748752 -45.8698480127447 27.4323115436746 -1.67211020258778 0.095084019951327 PLPP4 other 1 1 1 -0.5077133457863 -1.67211020258778 0.0621318488840303 4.80758494410363 2.04940172068602 2.34584800801979 0.0193735964099254 3.90417169681768 23.3218565150215 0.167403984082615 0.867119874062784 HIST2H3C other 1 1 1 2.34584800801979 0.167403984082615 0.809527589000909 24.7515718754347 43.1688171958637 0.573366922775136 0.566654064600868 135.582050551335 491.254081814723 0.275991702807815 0.782668472373003 HIST2H2AA3 other 1 1 1 0.573366922775136 0.275991702807815 0.185756015827737 8.75536325678877 4.98031475450962 1.75799395989197 0.0793640636356559 -35.5234107230479 56.4033810144829 -0.629809952597103 0.529108358435434 HIST2H2BF other 1 1 1 1.75799395989197 -0.629809952597103 0.684118631618128 -9.43623759679274 16.3690279680802 -0.576469025234334 0.564537957185236 12.5041896724439 31.7957556338001 0.393266001175057 0.694277952786713 PNLIPRP3 other 1 1 1 -0.576469025234334 0.393266001175057 0.0519641300986994 4.94485847511254 2.04273256547691 2.42070771215129 0.0158455121953975 3.9847217298035 23.2459626191136 0.171415647314477 0.863966302021531 HIST2H3A other 1 1 1 2.42070771215129 0.171415647314477 4.23373214334916e-06 230.449457332527 90.4504075672449 2.54779899317978 0.0111195526814707 -656.789995357581 217.117013953635 -3.0250507935681 0.00260558625267485 ATP1A1-AS1 other 0.0266090065209495 1 1 2.54779899317978 -3.0250507935681 0.452213226900585 -31.4906421729115 46.7954717205237 -0.67294208210963 0.501270949942977 -108.585519453515 86.9333661868363 -1.24906608608879 0.212180083816896 RBM20 other 1 1 1 -0.67294208210963 -1.24906608608879 0.000279621542766832 149.046670502694 95.8877244378915 1.5543873981412 0.120680070452383 -487.030408143974 210.807308944225 -2.3103108264279 0.0212483982875686 SNHG5 other 1 1 1 1.5543873981412 -2.3103108264279 2.46704651836106e-10 375.9738536263 55.3201808668935 6.79632365141638 3.08854250348756e-11 366.047054912893 329.57659767681 1.1106585160875 0.267253486554236 PCMTD2 other 2.08983510570365e-06 1 3.61081504082731e-07 6.79632365141638 1.1106585160875 0.415187166592596 6.20167126563797 5.88069032744447 1.05458218683877 0.292125774003109 -27.915786076307 40.8795080665534 -0.682879696860809 0.494999136824107 SOX18 other 1 1 1 1.05458218683877 -0.682879696860809 4.96689064145766e-17 55.831992574112 6.2633008748687 8.91414825657444 8.79413041913098e-18 -7.72630733412014 48.6132747178885 -0.158934105528938 0.8737838303483 LIME1 other 5.46059957121855e-13 1 1.17876524138032e-13 8.91414825657444 -0.158934105528938 0.717413709672313 11.3076712340648 14.3932554747598 0.78562290886131 0.432431735604075 14.5389282436668 27.342548150451 0.531732747206554 0.595128973436362 SAMD13 other 1 1 1 0.78562290886131 0.531732747206554 9.93759765533645e-08 17.4233837034318 7.07846212101934 2.46146456752144 0.0141480845075219 -55.9634378479933 13.942828406523 -4.01377942956047 6.8184325965608e-05 EFCAB7 other 0.000718749785827719 0.778051343593553 1 2.46146456752144 -4.01377942956047 0.875746022913024 0.275214280121852 4.55724748866869 0.0603904617438827 0.951866915853844 -4.76979975362789 10.2313254188191 -0.466195684173479 0.641262741583519 LDLRAD1 other 1 1 1 0.0603904617438827 -0.466195684173479 1.54229686925006e-08 32.137251827122 7.69666647463818 4.17547673827621 3.5139910891025e-05 -51.9290039520578 17.9424256038137 -2.89420199357104 0.00396899083582126 ARRDC1-AS1 other 0.000117877749716782 1 0.302800612147963 4.17547673827621 -2.89420199357104 6.47854546503034e-10 69.5026163201813 10.9592842726653 6.34189373967924 4.7882345026126e-10 5.4784633412126 22.7942767862871 0.240343810535302 0.810154611399607 ZYG11A other 5.35646139048709e-06 1 5.39729793134492e-06 6.34189373967924 0.240343810535302 1.48080807431912e-08 7.37814227630255 1.2634491288922 5.83968290260467 9.13697998813887e-09 22.537060387008 9.62265898613844 2.34208241396405 0.0195464471576155 LINC01270 other 0.000113341050008386 1 9.79301515128724e-05 5.83968290260467 2.34208241396405 0.162786238830833 -1.52143716350674 1.69479201883993 -0.897713198194164 0.369757950177158 -7.41083344880284 3.93028255500794 -1.88557268977011 0.0599151537132159 LCN6 other 1 1 1 -0.897713198194164 -1.88557268977011 0.695125273300323 -36.7406059174232 94.0833148981224 -0.390511388307348 0.696312725401826 411.71302809236 587.260340022515 0.701074123405941 0.483559308717547 SLC12A5-AS1 other 1 1 1 -0.390511388307348 0.701074123405941 0.113943267954498 4.43999758406994 3.49356244305883 1.27090832250374 0.204307465235419 -24.6716188452505 18.6110984559849 -1.32564012294055 0.185518417062297 LRRC73 other 1 1 1 1.27090832250374 -1.32564012294055 7.05679675449827e-08 44.0344911887869 9.06411835556321 4.85811079041793 1.55577524086522e-06 -32.0965668674767 20.2947453467834 -1.58152104493214 0.11434554110945 FOXO6 other 0.000516063546656458 1 0.0147969783158691 4.85811079041793 -1.58152104493214 7.61786745324516e-31 193.274721983294 18.0425097617067 10.71218608364 2.03276697716688e-24 -613.841278270554 119.240504585626 -5.14792586968432 3.69030723144644e-07 SYS1 essential 1.05027538577891e-26 0.00477119821953711 2.90055519971943e-20 10.71218608364 -5.14792586968432 3.19677216190616e-07 20.9225573120504 15.2894583704203 1.36843024815897 0.171745443769169 -149.289102450138 32.0107147453729 -4.66372287022166 3.91743382218741e-06 INPP5B other 0.00222527310190288 0.0483646379687258 1 1.36843024815897 -4.66372287022166 0.49335023325387 4.93187991958432 11.2270653138318 0.439284869351229 0.660629572545199 -19.1256001772676 21.7470676300067 -0.879456508926197 0.379542115831254 NEU4 other 1 1 1 0.439284869351229 -0.879456508926197 0.635212737854422 9.61793395905709 37.4642044521028 0.256723293600253 0.797492013610913 -198.242849076434 228.743885094336 -0.866658573166565 0.386521284971079 MAFB other 1 1 1 0.256723293600253 -0.866658573166565 1.24636144006593e-20 31.7546748201356 22.3130056401905 1.42314645244111 0.155262742358102 -377.40085826973 43.2590708702395 -8.72420166863469 3.21916628099246e-17 TRAF3IP1 other 1.49401345820703e-16 4.90439982909202e-13 1 1.42314645244111 -8.72420166863469 3.68184616149896e-20 23.4586764323178 62.0644168923395 0.37797304167073 0.705597516098575 -1139.55524821811 123.484786922429 -9.22830477031929 6.00298048211116e-19 GIGYF2 other 4.37145594754771e-16 9.20857205955851e-15 1 0.37797304167073 -9.22830477031929 0.347767940660612 50.5168344569862 34.7244407925005 1.45479187869013 0.146304698103253 31.6330475953509 70.6412427963197 0.447798571247659 0.654477170768055 C2orf72 other 1 1 1 1.45479187869013 0.447798571247659 8.23976310957952e-17 80.3828807455125 12.3638032831628 6.5014687555713 1.8047660561492e-10 -124.573110970588 32.302257293238 -3.85648315037927 0.000128820908671572 RUFY2 other 9.00029324459371e-13 1 2.06284760217853e-06 6.5014687555713 -3.85648315037927 0.00593137099516498 -12.2763427741174 11.9286620429211 -1.0291466662351 0.303868954912405 -95.5119697521098 29.72003513992 -3.21372331164636 0.00138803664892992 GGTA1P other 1 1 1 -1.0291466662351 -3.21372331164636 7.39746619704686e-21 209.121051096155 48.54057203886 4.30817030604295 1.95419300945097e-05 -452.256707531353 79.0873620631887 -5.7184447139609 1.77647980466707e-08 PHACTR4 other 8.91838524715969e-17 0.000240908426310901 0.171910359041402 4.30817030604295 -5.7184447139609 0.707912609059185 9.17340972048957 11.1007354325392 0.826378556289151 0.408950347087086 6.9604373388609 37.0053880277661 0.188092537595831 0.850873994170697 CLPSL1 other 1 1 1 0.826378556289151 0.188092537595831 4.16451970247619e-30 49.9622760384949 4.80555803532347 10.3967688395905 3.6317199017763e-23 -48.127920977817 13.7492518781529 -3.50040288768662 0.000503696050095756 TIMM23B other 5.70081102071965e-26 1 5.13597828509204e-19 10.3967688395905 -3.50040288768662 8.05059490439908e-07 139.784949669632 36.3990614180241 3.84034489417943 0.000137321864939409 -63.0566746252874 56.5426986191877 -1.11520454745132 0.265255183651634 ZDHHC18 other 0.00542368578709366 1 1 3.84034489417943 -1.11520454745132 0.230946069333707 -14.3409012029883 8.36805127086189 -1.71376832416458 0.0871378228742731 -12.9030619858185 21.8854490942474 -0.589572639348309 0.55572063059956 C10orf128 other 1 1 1 -1.71376832416458 -0.589572639348309 1.16474013119601e-08 11.5324028806029 5.84709765126919 1.97232944760203 0.0490789789437916 -76.8411384204082 15.6194619631067 -4.91957652586931 1.15146375817219e-06 AGAP9 other 8.96966375034049e-05 0.014578682642218 1 1.97232944760203 -4.91957652586931 1.39118911653468e-11 52.2262096058615 7.24733622356664 7.20626282468228 1.91819718365491e-12 31.9512822160414 20.1116728386589 1.58869341562798 0.112707431086552 GPRIN2 other 1.25179196705791e-07 1 2.31833311616533e-08 7.20626282468228 1.58869341562798 6.75911297946342e-12 160.756028038373 50.3938166620725 3.18999509635001 0.00150473009719273 -319.352974689923 80.0478282631704 -3.98952703176403 7.52693371285592e-05 TMEM57 other 6.17918108582546e-08 0.856188709837361 1 3.18999509635001 -3.98952703176403 0.000503874628566222 22.4257153246309 6.70532196708351 3.34446510319996 0.000881221731775048 -16.3126430606897 17.9570494575725 -0.908425579560378 0.36405567515294 PTPN20 other 1 1 1 3.34446510319996 -0.908425579560378 0.0800108411247061 -2.54258833552442 12.8294438122947 -0.198183831873351 0.842975138093723 -67.6466572946368 30.5521880159834 -2.21413462300138 0.0272326207931444 ZDBF2 other 1 1 1 -0.198183831873351 -2.21413462300138 1.86582414824636e-07 3.51661670357738 0.686469833115888 5.12275490332248 4.21284662328033e-07 -1.23704916387666 2.30174955454879 -0.537438645934334 0.59118853469163 GGNBP1 other 0.00132417539801044 1 0.00415470933987906 5.12275490332248 -0.537438645934334 6.1669619086967e-10 202.406099564188 43.7323109075545 4.6282964554984 4.62032315873186e-06 -468.625825391572 154.071906048921 -3.04160464687685 0.00246729991189902 DAXX other 5.11117802992783e-06 1 0.042613240492984 4.6282964554984 -3.04160464687685 5.92582470891593e-08 114.064052057454 100.551390609733 1.13438562476144 0.257133356093832 -1277.77026098125 245.114531340674 -5.21295189637423 2.64572084321045e-07 BMPR2 ts 0.000436436989811658 0.0034383788078363 1 1.13438562476144 -5.21295189637423 1.32655540500575e-06 119.011377177068 115.903169931132 1.02681727555668 0.304962024483538 -708.824219072975 183.460844078182 -3.86362671901208 0.000125156293303464 TCEA3 other 0.00876455156087298 1 1 1.02681727555668 -3.86362671901208 7.17560429050821e-13 119.483980968089 22.3728602452035 5.34057691589546 1.36549476139124e-07 -269.595605885854 77.1319652540294 -3.49525135263905 0.000512393373319511 RING1 other 6.81180115297945e-09 1 0.0013828365448609 5.34057691589546 -3.49525135263905 1.0660044089341e-05 35.0279763806034 13.4196352254999 2.61020331715451 0.00929958090320856 -139.20694549498 46.2024099919779 -3.01298017828833 0.00270805129757938 HSD17B8 other 0.0646851475341214 1 1 2.61020331715451 -3.01298017828833 2.25546114558273e-27 184.681373833669 20.3897216023313 9.05757211577389 2.4190088804541e-18 -291.073383965443 70.1996933048609 -4.14636261587895 3.92109491481527e-05 RXRB other 3.00562752260355e-23 0.455199908660905 3.2649362859489e-14 9.05757211577389 -4.14636261587895 5.0372596327276e-20 132.276735271633 16.8943058551337 7.82966381725815 2.6649708771693e-14 -212.956078422843 47.4674879418736 -4.48635661283823 8.88413963094297e-06 OXLD1 other 5.96965639074548e-16 0.107658004047767 3.36132776737364e-10 7.82966381725815 -4.48635661283823 0.00885183143111893 173.125137186328 56.6645776581513 3.05526211155699 0.00235867138775915 110.140403491149 197.587203420235 0.557426804897373 0.577464720712846 COL11A2 other 1 1 1 3.05526211155699 0.557426804897373 0.855937221498105 -15.0298815795622 30.7178400396688 -0.489288360124042 0.62483369899256 9.83496796549093 107.610048660121 0.0913945127611083 0.927212580579039 HLA-DOA other 1 1 1 -0.489288360124042 0.0913945127611083 2.10974704196782e-14 581.340105837489 128.003650114065 4.54159006652898 6.87312485297848e-06 -2229.40470163006 450.813198824382 -4.94529598388831 1.01301290395673e-06 BRD2 other 2.12831281593714e-10 0.0128581727899228 0.0626897717840167 4.54159006652898 -4.94529598388831 0.0970938064919878 92.1079075213341 59.3161797171551 1.55282939596825 0.121042257469441 403.314093450198 208.904329653912 1.93061624964098 0.0540470438845601 HLA-DMA other 1 1 1 1.55282939596825 1.93061624964098 5.04027450845208e-09 401.645152438098 64.1656595640133 6.25950321662954 7.81837560566933e-10 587.319240593717 225.323429427087 2.60656089820331 0.0093954865900326 PSMB8-AS1 other 3.97072825775855e-05 1 8.74094392713832e-06 6.25950321662954 2.60656089820331 0.0283983186272125 87.6295226234931 731.044921653685 0.119868861718193 0.904632975032307 -4982.11796221688 1949.67269253115 -2.55536120565389 0.0108890391386656 COL5A2 other 1 1 1 0.119868861718193 -2.55536120565389 1.26078871758456e-05 381.350179771395 79.600360940659 4.79080968057026 2.14336697991346e-06 353.279196704097 279.523758232236 1.2638610719114 0.206819214541727 PSMB8 other 0.07596252023447 1 0.0202183807215236 4.79080968057026 1.2638610719114 2.3326622844893e-10 584.698316234452 86.1475007813109 6.78717677160169 2.98745219244344e-11 767.287329381575 302.514623000994 2.53636443015535 0.0114784903664393 TAP2 other 1.97926394838917e-06 1 3.49472157472033e-07 6.78717677160169 2.53636443015535 0.0273998020951361 17.1421830186196 7.72064697009792 2.2203039570403 0.0268148055010106 -23.5205883154578 22.7160544717667 -1.03541697105415 0.300940261614943 TNRC6C-AS1 other 1 1 1 2.2203039570403 -1.03541697105415 0.0553608857819886 577.376924782019 615.090512044093 0.938686117695519 0.348306974077629 5114.26512930872 2124.81290590656 2.40692491799729 0.0164184310738191 HLA-DRA other 1 1 1 0.938686117695519 2.40692491799729 0.0803279606734947 -328.971788016169 146.347957745671 -2.24787412877922 0.0249846892694177 -193.740271139734 307.640418485615 -0.629762084232742 0.529115147157324 COL15A1 other 1 1 1 -2.24787412877922 -0.629762084232742 0.0039722795032437 -70.6496053687165 21.5352212792473 -3.28065379280773 0.00110187642214718 -125.88581147826 75.4474282043255 -1.66852355970754 0.0957861867411897 NOTCH4 other 1 1 1 -3.28065379280773 -1.66852355970754 2.06250388693593e-24 236.445582194824 29.7517457502936 7.94728430994646 1.10829067495816e-14 -474.231789966309 103.122634404993 -4.59871678708148 5.29439144308494e-06 PBX2 other 2.64206747916492e-20 0.0649780661809815 1.40974573854678e-10 7.94728430994646 -4.59871678708148 0.00168296256225684 7.57564088912095 2.84804032494726 2.65994860492757 0.00804705131145519 -14.0387047478867 9.87016886019664 -1.42233683604954 0.155504784013356 AGER other 1 1 1 2.65994860492757 -1.42233683604954 2.58360877638255e-15 122.770653925028 20.8818974164675 5.8792863252077 7.21545001445416e-09 -277.684533805337 72.3683059598726 -3.83710147864052 0.000139182922164816 RNF5 other 2.69367051025645e-11 1 7.76959657556424e-05 5.8792863252077 -3.83710147864052 3.8980538420016e-19 59.6958346860318 7.16367778317588 8.3331267112864 6.54548534346813e-16 -43.788493378898 24.9231373360243 -1.75694146320839 0.0794944915861253 FKBPL other 4.52408128902706e-15 1 8.50520365530248e-12 8.3331267112864 -1.75694146320839 5.10638498161628e-34 296.694513772761 23.0848980270238 12.8523207434333 3.45756349820526e-33 -73.4216845744478 83.7579524023444 -0.876593594620786 0.381095768804054 MRPL38 other 7.23217304946314e-30 1 5.14001389643194e-29 12.8523207434333 -0.876593594620786 4.50264664964781e-05 5.45130617421123 1.39304423261236 3.91323265018546 0.000102771719202021 -7.20331426992034 4.95002623966291 -1.45520729005487 0.146196187985417 SMIM5 other 0.256470753163939 1 0.848380542012687 3.91323265018546 -1.45520729005487 0.15914764599643 3.14840413273568 2.45140317073986 1.2843273478289 0.199577141736661 -6.11768076472972 6.09398975492572 -1.00388760249963 0.315881585854136 ERICH2 other 1 1 1 1.2843273478289 -1.00388760249963 0.247821980807339 -3.33192322134241 9.67248780034246 -0.344474274883494 0.730623502362266 35.3752731474586 24.0450213426709 1.47120988762363 0.141815769607297 SP5 other 1 1 1 -0.344474274883494 1.47120988762363 0.00435724968777492 -23.8671551193355 9.42306689414359 -2.53284364713242 0.0116194430721343 -101.746919814344 36.1922602781216 -2.81128945891921 0.00512846938184036 CYP21A1P other 1 1 1 -2.53284364713242 -2.81128945891921 0.000254052789956512 -105.379720274511 52.6364207632947 -2.00203050941481 0.0458105138924828 -802.747252421581 199.94979120212 -4.01474413949311 6.84506191497848e-05 STK19 other 1 0.781021564499045 1 -2.00203050941481 -4.01474413949311 6.61066001565808e-11 57.0035793788232 10.381986252884 5.49062366201728 6.26708187132037e-08 -83.4609743893485 35.7360194087907 -2.33548603817967 0.0198966448313454 DXO other 5.75656274163505e-07 1 0.000647765582219674 5.49062366201728 -2.33548603817967 1.12537103159656e-18 209.107776537285 27.2243833932116 7.68090037217981 7.85759295332289e-14 -255.158754484926 93.4161210227147 -2.73142099769784 0.00651961866026011 SKIV2L other 1.29080057324125e-14 1 9.81020480222363e-10 7.68090037217981 -2.73142099769784 2.19900012650994e-06 6.83387607586709 5.88836105762373 1.16057354652517 0.246326292658619 -55.7047777671925 12.748145980207 -4.36963758131425 1.49191037701154e-05 C9orf129 other 0.0142341278188989 0.178238532741569 1 1.16057354652517 -4.36963758131425 3.445041802464e-11 40.5960650559838 8.21166587566999 4.94370638925583 1.0317932923789e-06 -90.1616299822604 28.1711975625506 -3.2004897832997 0.00145460132414231 ZBTB12 other 3.04197191157571e-07 1 0.00992069250622315 4.94370638925583 -3.2004897832997 3.5106545264293e-44 175.934296373571 33.9533252005774 5.18165143868086 3.10198709376299e-07 -575.10703891649 62.7798589517045 -9.16069338988019 1.03996167978373e-18 SDHD ts 5.22701352440058e-40 1.59467723978037e-14 0.0030821343763629 5.18165143868086 -9.16069338988019 6.06471288060566e-22 397.394199618278 48.0593330299511 8.26882469156651 1.10443832565691e-15 -515.677388649748 164.034047371768 -3.14372166578937 0.00176192419457167 EHMT2 other 7.46444861344945e-18 1 1.42859097423721e-11 8.26882469156651 -3.14372166578937 0.00136126689188181 18.7989712868451 5.25705099082989 3.57595376564483 0.000379977820005177 5.53968595553144 13.0816706148368 0.423469304390564 0.672119953788545 PKP4-AS1 other 1 1 1 3.57595376564483 0.423469304390564 0.37015383560231 -3.74491602452408 8.43935101245682 -0.443744550854258 0.657404373458146 -21.1106311042154 15.5659553767124 -1.35620529503753 0.175598556118108 LAYN other 1 1 1 -0.443744550854258 -1.35620529503753 1.21236245137141e-05 -522.029803898025 164.081782445708 -3.18152201979372 0.00155101643500858 -2496.69043203343 560.114215773769 -4.45746664112851 1.01308384210827e-05 SLC44A4 other 0.0731660739402649 0.12228935058089 1 -3.18152201979372 -4.45746664112851 1.5689850560366e-07 335.952993589922 70.5161897493024 4.76419663036665 2.45264025406847e-06 -323.069996590411 240.716060808601 -1.34212065246154 0.180132608752238 NEU1 other 0.00112041222851574 1 0.0230670815895139 4.76419663036665 -1.34212065246154 4.40877549532849e-06 254.167133280584 65.4453921186464 3.88365208080354 0.000115932600424901 -410.081860311442 226.402366798545 -1.81129670201874 0.0706619721727706 C6orf48 other 0.0276782925596723 1 0.951922582088862 3.88365208080354 -1.81129670201874 0.019250827357221 1013.19147729711 548.877699294166 1.84593303499129 0.0654636379479441 -2749.25447047187 1896.1798534905 -1.44989119329109 0.147684840907588 HSPA1B other 1 1 1 1.84593303499129 -1.44989119329109 0.0638446181378701 935.473975363436 612.69752546055 1.52681206711299 0.127406535445674 -2591.28652418746 2119.85339373298 -1.22238949723985 0.222105753686349 HSPA1A other 1 1 1 1.52681206711299 -1.22238949723985 0.000251685648279803 4.21965885620295 3.34925548109821 1.25987965982796 0.208266210666528 -38.5993388406577 11.638597499279 -3.31649400566082 0.000973902924035347 HSPA1L other 1 1 1 1.25987965982796 -3.31649400566082 4.14293683580352e-21 254.357939387828 26.5238193733497 9.58979307646013 3.40944941293591e-20 -10.6176635697699 92.1697552104245 -0.115196829432059 0.908332659508888 LSM2 essential 5.0162679207909e-17 1 4.69788034608439e-16 9.58979307646013 -0.115196829432059 8.33093968332328e-25 588.941984563027 55.8144390947246 10.5517854181695 9.42898944520476e-24 3.37266683170043 194.683456034861 0.017323849187763 0.986184791328967 VARS essential 1.0739414345772e-20 1 1.33976511026914e-19 10.5517854181695 0.017323849187763 0.0726576173097829 12.7195474401629 7.00052703974613 1.81694140568939 0.069787550598966 -19.0085919413246 24.5859460485881 -0.773148688431951 0.439777124205433 VWA7 other 1 1 1 1.81694140568939 -0.773148688431951 0.141871193694156 5.32993119390484 19.2999046487878 0.276163602406171 0.782528070165812 -55.1813771501255 37.7985451759655 -1.45988097936672 0.144904288483938 CARD16 other 1 1 1 0.276163602406171 -1.45988097936672 9.77832419595048e-15 15.0855578403656 14.7006596653391 1.02618237438243 0.305275515561427 -257.855100223127 34.7082715941975 -7.42921178092414 4.42320689098486e-13 MBD5 other 9.99051383100261e-11 6.52290320213538e-09 1 1.02618237438243 -7.42921178092414 2.36163757771054e-11 48.7904963196288 7.90796248260084 6.16979360068767 1.33923899664395e-09 -42.7146090728076 27.5373848066185 -1.55114980499315 0.121449477180149 MSH5 other 2.10138511664684e-07 1 1.48334111268284e-05 6.16979360068767 -1.55114980499315 0.000610776239778876 1.39617067097248 1.45418008007204 0.960108510703373 0.337427135318951 -16.6182131145452 5.0766540240522 -3.27345787910923 0.00112988370171514 MPIG6B other 1 1 1 0.960108510703373 -3.27345787910923 0.417825360264437 0.573231708142927 9.90583719251551 0.0578680728344737 0.953874963977565 -42.8344994969812 34.5820362513139 -1.23863439346645 0.21601512388294 LY6G6C other 1 1 1 0.0578680728344737 -1.23863439346645 1.2723943497666e-18 157.788225555326 26.5589232834911 5.94106259019191 5.05755093825099e-09 -457.022545250815 91.5595423800458 -4.99153374264153 8.07704690623152e-07 ABHD16A other 1.45765496709262e-14 0.0103030810335889 5.47530464575052e-05 5.94106259019191 -4.99153374264153 0.329267081748527 -4.44292379731644 3.12822261387157 -1.42027097995362 0.15610165809998 -0.330905792352102 10.7984248194324 -0.0306438946314299 0.975564774747019 LY6G5C other 1 1 1 -1.42027097995362 -0.0306438946314299 4.43159308575191e-19 593.813725984425 71.7539275860197 8.27569648048258 9.91065134758172e-16 -452.123725057166 247.97378205665 -1.8232722883336 0.0688107966538661 CSNK2B essential 5.13621638638647e-15 1 1.28313202997140e-11 8.27569648048258 -1.8232722883336 7.63507873252521e-16 87.1507358153522 13.7698144395899 6.32911476023841 5.152269068021e-10 -167.646200211449 48.2453420210184 -3.47486810516159 0.000551790981032295 GPANK1 other 8.10387256670226e-12 1 5.79887883605763e-06 6.32911476023841 -3.47486810516159 5.59830168430523e-18 117.015405690874 16.2734503803506 7.19057132666615 2.1395795327854e-12 -180.438046747467 57.0173391156804 -3.16461710676085 0.00163953888604746 C6orf47 other 6.31600396023316e-14 1 2.5822585381187e-08 7.19057132666615 -3.16461710676085 0.000490993687975439 -17.6586648088219 10.7821780339764 -1.63776416538259 0.102056691268243 -99.9558528715938 25.497293565366 -3.92025344240331 9.99043316752724e-05 FAM155A other 1 1 1 -1.63776416538259 -3.92025344240331 0.00656465033679482 5.03336688689143 3.40845719402776 1.47672879557085 0.14032591877889 -26.1457758973385 11.9422221563915 -2.1893560138927 0.0289943139278914 APOM other 1 1 1 1.47672879557085 -2.1893560138927 4.21793293458104e-33 905.449148637546 84.6553184376326 10.69571487472 2.29332184216809e-24 -1088.7537083433 296.607104608409 -3.67069328895784 0.000265697076288496 BAG6 other 5.93420984566207e-29 1 3.27073561130014e-20 10.69571487472 -3.67069328895784 2.495650426698e-22 1297.55801634674 158.495664245729 8.18670985431519 1.91236911117224e-15 -1931.66256683708 555.321755709254 -3.47845649297492 0.000544615288847069 PRRC2A other 3.09335870389217e-18 1 2.46504378430101e-11 8.18670985431519 -3.47845649297492 0.590747681442837 -8.21572397708879 16.0411098199537 -0.512166805744897 0.608741752836591 37.9364581518951 56.2032867658189 0.67498647027467 0.49997060838466 AIF1 other 1 1 1 -0.512166805744897 0.67498647027467 0.709830701535687 0.257703108396264 0.606161010243834 0.425139697277132 0.670902646516806 1.71417484231402 2.11543764136996 0.810316886109635 0.41811175090041 NCR3 other 1 1 1 0.425139697277132 0.810316886109635 0.279824536186585 -6.67441741175546 7.28131186164752 -0.916650397425123 0.359731299235141 23.8828911627472 25.4110062019441 0.939864048394904 0.347703663221926 LST1 other 1 1 1 -0.916650397425123 0.939864048394904 3.89093396699867e-05 62.6979787324328 19.11771657141 3.2795746551759 0.00110601656607228 -129.991251404606 67.6983456912716 -1.92015403149454 0.0553600381873601 NFKBIL1 other 0.223106153667704 1 1 3.2795746551759 -1.92015403149454 0.244673679095625 -4.78003601510746 5.23996058006758 -0.912227476155138 0.362051576261109 -30.2906658252563 18.5746493498973 -1.63075303628403 0.103519104887125 MCCD1 other 1 1 1 -0.912227476155138 -1.63075303628403 1.08225654812048e-34 421.073855570297 33.3389939031291 12.6300708651792 3.68311630127745e-32 -418.40952378857 164.923378665802 -2.53699340368491 0.0114660034289889 ZNF814 other 1.54015929363026e-30 1 5.45580017708228e-28 12.6300708651792 -2.53699340368491 0.00886268852655144 27.5248159866886 11.2170017394302 2.45384788431769 0.0144449616539357 -38.7886131385232 39.7621071539467 -0.975517041598062 0.329735849241387 MICB other 1 1 1 2.45384788431769 -0.975517041598062 1.15117661915132e-32 77.1755056274195 5.93629322617517 13.0006222211406 8.05540242059013e-34 60.8538954275145 29.9858288763582 2.02942182050181 0.0429043416829696 ZNF551 other 1.61371938472632e-28 1 1.19961052847428e-29 13.0006222211406 2.02942182050181 2.15583225116053e-05 29.8411574678218 10.9768652902052 2.71855003034877 0.00676536096576897 -105.905644038098 38.9108697691752 -2.72174959507063 0.00670109505027826 MICA other 0.126870727980797 1 1 2.71855003034877 -2.72174959507063 3.71239650113976e-17 15.7985148975003 1.85570917618704 8.51346487921226 1.63351097990601e-16 -12.9686218376743 8.42640222255496 -1.53904614272521 0.124371278317908 ZNF805 other 4.09774325795807e-13 1 2.14479991661658e-12 8.51346487921226 -1.53904614272521 0.000103570095131914 4778.30884174458 1142.97123775555 4.1806028742488 3.38597106850816e-05 1357.31418255516 4096.74615063309 0.331315178594945 0.740533548161298 HLA-C other 0.56130299609046 1 0.292175443501569 4.1806028742488 0.331315178594945 2.27276643979932e-09 12.1737820612467 1.92620600744722 6.32008311373739 5.4268637611271e-10 6.65808195721587 6.92951976789898 0.960828770279213 0.337062791629027 POU5F1 og 1.82775877088661e-05 1 6.10196561301131e-06 6.32008311373739 0.960828770279213 5.13042675220599e-18 221.465027203482 25.0219296419822 8.85083726044471 1.2042631760721e-17 28.2695893529766 90.0163094781771 0.314049637414097 0.753603073203294 CCHCR1 other 5.79173876056535e-14 1 1.61009986640839e-13 8.85083726044471 0.314049637414097 0.219589202140306 7.17641535830871 4.73412313553425 1.51589114876262 0.130124525228397 -5.47126867474196 17.0309923884148 -0.321253662145005 0.74814087851585 PSORS1C2 other 1 1 1 1.51589114876262 -0.321253662145005 0.0588746607046881 214.41285865415 89.8685181455153 2.38585060796232 0.0173789030858099 261.955324633285 324.984543364399 0.806054718545674 0.420561578568777 CDSN other 1 1 1 2.38585060796232 0.806054718545674 0.0289980751595629 238.437190792381 89.4313660335636 2.66614725199317 0.00789955801681424 238.104821616376 321.671080435703 0.740212086501103 0.459488900290794 PSORS1C1 other 1 1 1 2.66614725199317 0.740212086501103 0.000137963055961415 631.458146509103 149.249098151686 4.23090091886072 2.72901943707064e-05 521.550798359516 536.251527218349 0.972586131483692 0.33118891793322 C6orf15 other 0.736584755777997 1 0.237315530247663 4.23090091886072 0.972586131483692 9.29544105910684e-40 226.135343237469 17.16841757322 13.1715891853775 1.48456181684731e-34 -150.200645623787 66.1478975880254 -2.27067905558011 0.0235594152777432 DHX16 essential 1.3602018901791e-35 1 2.2158569678263e-30 13.1715891853775 -2.27067905558011 3.14287045653711e-31 93.6140703430489 7.73175731872254 12.1077352125837 5.06623956793066e-30 -2.85152865481049 29.7895533536002 -0.0957224373579226 0.923776531888543 C6orf136 other 4.35130414707563e-27 1 7.44787878881487e-26 12.1077352125837 -0.0957224373579226 1.26513287432927e-34 435.02483184578 35.2960614789776 12.3250247652952 6.2450186424157e-31 -221.66518405298 135.968523078559 -1.63026838149082 0.103627892469514 MRPS18B essential 1.80003105359569e-30 1 9.21390050502013e-27 12.3250247652952 -1.63026838149082 3.0674010340925e-05 187.956472553213 45.0381501260128 4.17327248182545 3.49908050989269e-05 -115.013095495806 173.497282649275 -0.662910068328303 0.507671009031238 PPP1R10 essential 0.17775588992566 1 0.301585749147651 4.17327248182545 -0.662910068328303 8.20617084699902e-44 591.803073137836 41.4913039107475 14.2633038096578 2.06239107461086e-39 -254.246709521398 158.409475646077 -1.60499685062681 0.109078047567152 ABCF1 essential 1.22050379007416e-39 1 3.11421052266239e-35 14.2633038096578 -1.60499685062681 7.60039303344713e-25 68.8640121866875 7.2193195952662 9.53885075704953 4.8599439369297e-20 -72.5748223190226 27.3748846377459 -2.65114623420011 0.00825656778510481 PRR3 other 9.80374697384345e-21 1 6.68776885160897e-16 9.53885075704953 -2.65114623420011 0.0349033003940232 16.7054216357609 8.67874807886847 1.92486537043704 0.0547682891868879 -33.4182670503542 25.5311019810657 -1.30892380106184 0.19111382686863 LINC01123 other 1 1 1 1.92486537043704 -1.30892380106184 6.54390915567735e-19 298.902759505974 33.1692549300613 9.01144026708539 3.47306213959223e-18 -37.1402945188253 125.77425271847 -0.295293303009792 0.767882915916274 GNL1 other 7.54250969283371e-15 1 4.67890931445865e-14 9.01144026708539 -0.295293303009792 2.9236654957591e-06 1990.06411181522 391.481087815959 5.08342337280614 5.10377040826784e-07 1498.41448144119 1487.75760014729 1.00716304947315 0.314303372167126 HLA-E other 0.0186999959923767 1 0.00500271575418413 5.08342337280614 1.00716304947315 3.62199009642608e-19 127.935856757326 13.9144901002739 9.19443370438757 8.00972570446709e-19 -81.8884087081884 61.4746548455702 -1.33206780768269 0.183396716375695 ZNF468 other 4.20585489996996e-15 1 1.0874804588955e-14 9.19443370438757 -1.33206780768269 3.87155997018503e-14 54.9464146889625 6.95625062341606 7.8988549526957 1.57619873226787e-14 -9.20418070899192 29.3785069975506 -0.313296407804499 0.754176004086843 ZNF616 other 3.86768841021485e-10 1 1.99672855403693e-10 7.8988549526957 -0.313296407804499 0.000998503604200428 22.9366432606092 9.20316487301628 2.49225604203392 0.0129893973543197 -73.5017244425401 36.5033724087475 -2.01355983276018 0.0445468048000337 RNF39 other 1 1 1 2.49225604203392 -2.01355983276018 1.71265597362488e-33 325.213420767116 28.6132136851845 11.3658474138998 5.24680110458454e-27 -381.838688160316 113.479343774144 -3.36482989292115 0.000819918940264463 PPP1R11 essential 2.41638631318735e-29 1 7.60261480054299e-23 11.3658474138998 -3.36482989292115 3.33074731298248e-06 362.898314306664 71.6246142213317 5.06667042122208 5.55480635005382e-07 288.020809380254 289.715000873038 0.994152213424648 0.320590756715098 HLA-J other 0.0211868836578816 1 0.0054292677265426 5.06667042122208 0.994152213424648 3.03684546531829e-06 192.951174643985 39.7620252999942 4.85264956169153 1.59353479212842e-06 -33.0358262643444 160.833748561688 -0.205403570828752 0.837333667857087 ZNRD1ASP other 0.0193932951415226 1 0.015151328803557 4.85264956169153 -0.205403570828752 0.71096904265198 -4.52194541663029 8.86052616140817 -0.510347278960196 0.6100155769241 4.42436777750903 14.4377110477168 0.306445236567379 0.759383136749732 DISP3 other 1 1 1 -0.510347278960196 0.306445236567379 1.21124058473601e-11 1736.76720705387 679.125195357484 2.55735940725871 0.010831281449656 -9984.90886256292 1792.59326078736 -5.57009171069697 4.09986953221089e-08 RACK1 other 1.0929023796073e-07 0.00054958751079287 1 2.55735940725871 -5.57009171069697 6.18234527124538e-06 147.082455031728 30.2110817138997 4.86849350263608 1.4758816494262e-06 54.8642973358547 120.356389410783 0.455848647541261 0.648680728103553 HLA-G other 0.0382254408121102 1 0.0140503933025374 4.86849350263608 0.455848647541261 7.99259428373786e-07 94.2197440142118 33.6657513152492 2.79868235025945 0.00531317970314409 -504.265222877215 125.978511302383 -4.00278759975851 7.12854749769301e-05 TBC1D8 other 0.00538700854723932 0.812511843787049 1 2.79868235025945 -4.00278759975851 6.11278775459242e-13 887.605681108682 115.473039485803 7.68669193312271 7.11876055091894e-14 768.731983926911 450.712276086365 1.70559362305811 0.0886556530282389 HLA-F other 5.81876266359653e-09 1 8.89702693653849e-10 7.68669193312271 1.70559362305811 9.44141119944539e-29 193.195348437076 16.0147032386774 12.063623381449 7.42715208951332e-30 183.257099349176 62.5082995969757 2.93172427550793 0.00351292658328225 ZFP57 other 1.27695086472499e-24 1 1.09104864194951e-25 12.063623381449 2.93172427550793 2.43036246992931e-38 108.167892605855 8.80473436708548 12.2851965881238 9.86176226584491e-31 -42.7214786850241 21.6863199726241 -1.96997363955498 0.0493567390058847 LINC02210 other 3.53326095878323e-34 1 1.45391961085351e-26 12.2851965881238 -1.96997363955498 7.3839850753237e-12 177.018597992484 30.7693364631014 5.75308467261766 1.47048335210541e-08 -276.245290538458 101.778633363763 -2.71417763639192 0.00685682932453809 AKT1S1 other 6.73936317824795e-08 1 0.000156430018996974 5.75308467261766 -2.71417763639192 0.154247038097458 324.404036585796 172.127863634393 1.88466893003938 0.0600083726873268 59.2904261434356 671.846359479253 0.0882499775534864 0.929710532488954 GABBR1 other 1 1 1 1.88466893003938 0.0882499775534864 3.42828595649629e-10 32.4703989678807 4.8309695299123 6.72130071755393 4.61066185847046e-11 34.6141425758371 18.4251462492669 1.87863597431224 0.0608356952270433 CASC10 other 2.87907454626558e-06 1 5.35851121191436e-07 6.72130071755393 1.87863597431224 0.0422320365130869 3.14485247554183 1.40178733406396 2.2434590462624 0.025270304931449 -1.21979076469753 3.15901042825438 -0.386130654646673 0.699551432265468 MAMDC2-AS1 other 1 1 1 2.2434590462624 -0.386130654646673 0.00364381131632621 198.709555812308 60.2809375018279 3.29639126475568 0.0010458438593815 86.8884064176021 148.037609607943 0.586934675909143 0.557500848313365 SPDYC other 1 1 1 3.29639126475568 0.586934675909143 6.43507764598275e-32 325.659273056104 30.1932645279598 10.7858251880824 1.0527506517746e-24 -344.142180991746 106.296169568393 -3.23757838489484 0.00127920937360464 TRIM27 other 8.96277614532478e-28 1 1.50459123151626e-20 10.7858251880824 -3.23757838489484 0.0529014194140534 -89.4209528300522 40.7048369660211 -2.19681392913323 0.0284586955863701 -231.835521835089 157.993164226728 -1.46737691449988 0.142856794493467 MALRD1 other 1 1 1 -2.19681392913323 -1.46737691449988 0.323358453482711 9.32481427249989 6.72133684105651 1.38734518043201 0.165909875878195 18.3041086117 17.5480726454815 1.04308370391965 0.297377130796105 RANBP17 other 1 1 1 1.38734518043201 1.04308370391965 0.894266979291262 -2.06072543065448 5.07413293940365 -0.406123658024749 0.684811740075255 -4.89969138626447 13.0924310512606 -0.37423847160858 0.70837299698662 FAM196B other 1 1 1 -0.406123658024749 -0.37423847160858 0.581043400173514 -2.89058331173666 8.83589938050473 -0.327140813544613 0.743686994460545 -30.9693197863002 30.1318567268492 -1.02779327762782 0.304503011018667 LINC01291 other 1 1 1 -0.327140813544613 -1.02779327762782 2.0598855830482e-17 8.58829314357809 2.61302541464622 3.28672392370928 0.0010803517442359 -38.0507900894742 5.98983610437712 -6.35255947348347 4.54373625990024e-10 TTC25 other 2.28770892853333e-13 6.4130293572232e-06 1 3.28672392370928 -6.35255947348347 0.0117803421673646 69.3331582080998 28.552473086884 2.42827155452075 0.0154959428231144 -133.916088623121 97.7112029338522 -1.37052952580861 0.171090041605143 MRPL53 essential 1 1 1 2.42827155452075 -1.37052952580861 2.82523598356651e-12 102.105461883757 13.7135508492423 7.44558889278468 3.77626573691047e-13 99.4797735048992 59.9489550511923 1.65940796499205 0.0976067904448468 ST8SIA6-AS1 other 2.62492675233165e-08 1 4.63725432492606e-09 7.44558889278468 1.65940796499205 3.75524786596428e-08 76.0575216948081 12.9324549825423 5.88113562331972 7.40194866252057e-09 -17.0411340527963 88.725522432178 -0.192065750481465 0.847767603887485 MROH6 other 0.000280441910630213 1 7.96523695573838e-05 5.88113562331972 -0.192065750481465 7.0212768655611e-20 112.410976258097 22.686904129369 4.9548839108716 9.71426232788301e-07 -325.181111853667 50.141948494645 -6.48521091852654 2.01221681129373e-10 ATXN2 other 8.29353223360078e-16 2.86117108397855e-06 0.00935094891682019 4.9548839108716 -6.48521091852654 2.30525935315386e-05 321.765393005593 106.303389084797 3.0268592165855 0.00258875179986876 -1115.19746086649 363.787472693294 -3.06551914119018 0.00228139494439612 DCTN1 essential 0.135180408468942 1 1 3.0268592165855 -3.06551914119018 3.8726833492675e-25 85.1909419256406 29.8084540884768 2.85794565772444 0.00442847050034416 -622.282678726682 66.4865595929524 -9.35952593330824 2.1385054834577e-19 TCTN1 other 5.01009044894737e-21 3.28581367533275e-15 1 2.85794565772444 -9.35952593330824 0.02092232600096 18.4811363940204 6.91800904545483 2.6714530542805 0.00778030270160817 0.915142594239469 15.532368496158 0.058918418943372 0.953038883881501 FAM216A other 1 1 1 2.6714530542805 0.058918418943372 2.27956564076452e-11 25.5417934442204 17.259069202243 1.47990561628324 0.139478366145816 -152.006986757864 28.3552445521372 -5.36080676286767 1.22708181615269e-07 ZBTB48 other 2.0299532031008e-07 0.00161790737459732 1 1.47990561628324 -5.36080676286767 0.231770369995414 -7.20827581494778 6.06184861384301 -1.18912171420559 0.234910554900211 13.4780708997011 18.0772099921014 0.745583577642246 0.456241029993286 IGFL2 other 1 1 1 -1.18912171420559 0.745583577642246 3.78875667796962e-19 149.513546575868 18.9692470797457 7.88189146081133 1.99946184675128e-14 -45.4772307033174 35.5441677251328 -1.27945690148095 0.201323731444623 MZT1 other 4.39798875178714e-15 1 2.52731977429362e-10 7.88189146081133 -1.27945690148095 1.68007470097335e-14 11.5105356974095 4.19285100596807 2.7452765865101 0.00624518717656001 -89.4947372369091 13.6903526825274 -6.53706586764043 1.44195816952254e-10 ZNF155 other 1.7017476646159e-10 2.05493458738657e-06 1 2.7452765865101 -6.53706586764043 5.15425489369864e-07 112.09554490627 29.1748019435963 3.84220414325293 0.000137094357842687 -145.046914906479 72.7755405474178 -1.99307231269512 0.0467786672608434 UQCC3 other 0.00352447949631113 1 1 3.84220414325293 -1.99307231269512 1.90523083693184e-06 14.526383345701 3.02938751849351 4.79515521108533 2.09830776435609e-06 -10.9868835362308 9.88252074551108 -1.11174909915786 0.266734433340371 FBXO48 other 0.0124144841334479 1 0.0198038286799928 4.79515521108533 -1.11174909915786 1.44226486423512e-11 111.563039500478 20.9470338670241 5.32595880680301 1.47106596693336e-07 -183.634547726322 64.723528876531 -2.83721470250225 0.00472030158546591 ATP6V0E2-AS1 other 1.29688456592022e-07 1 0.00148665926618285 5.32595880680301 -2.83721470250225 0.519192082181974 225.958646385114 207.850643100801 1.08712026585133 0.277468663606132 -11.0019579905767 734.186241507095 -0.0149852413033409 0.988049489545719 CD177 other 1 1 1 1.08712026585133 -0.0149852413033409 1.36001440333916e-15 107.711001468189 16.6683670430289 6.46200081808474 2.31718751406335e-10 -167.210625861811 51.8415431338386 -3.22541760437428 0.00133430499905066 ZNF783 other 1.43182316383546e-11 1 2.63858142226393e-06 6.46200081808474 -3.22541760437428 1.6891609533591e-14 3.98674292915818 3.80153644076568 1.04871885125352 0.294778413175882 -87.1660279682994 11.8234446637792 -7.37230396445547 6.36913470054518e-13 ZNF425 other 1.71044438137142e-10 9.37472936573245e-09 1 1.04871885125352 -7.37230396445547 0.00211795984546323 30.057294538815 9.69878749490074 3.09907754496302 0.00204671346428478 -10.0783661617551 25.0585960447069 -0.402191972119042 0.687708652883729 LRRC10B other 1 1 1 3.09907754496302 -0.402191972119042 2.00395566286388e-23 56.0749364912771 6.16253741066325 9.0993259358148 1.6838214193884e-18 -37.0369841309213 14.747945959743 -2.51133169541168 0.0123147404761736 C12orf73 other 2.52738888200392e-19 1 2.27720008758087e-14 9.0993259358148 -2.51133169541168 0.012174243142606 40.5166613595301 79.5763657677685 0.509154457716401 0.610851944410416 -501.565118783408 196.632888586031 -2.55076921460147 0.0110232940038417 PCDHGA1 other 1 1 1 0.509154457716401 -2.55076921460147 7.3157781277604e-05 18.9233611338666 35.5731176079841 0.531956781027803 0.594986669009301 -380.385246245056 96.7199788026997 -3.93285080242841 9.5510084576004e-05 PCDHA9 other 0.405074634934093 1 1 0.531956781027803 -3.93285080242841 6.65591980796209e-05 18.7649243289199 35.6054038642054 0.527024616838697 0.598404314351248 -381.388824961346 96.4176788335146 -3.95559019440712 8.70875550338605e-05 PCDHA8 other 0.370401937313091 0.986005298093368 1 0.527024616838697 -3.95559019440712 0.000119912065732614 23.1939415639247 36.017941962058 0.643955215108006 0.519891707594303 -365.991032706833 97.1467077517967 -3.7674054136957 0.00018404649444544 PCDHA7 other 0.64548664983866 1 1 0.643955215108006 -3.7674054136957 5.08804497080475e-05 20.6955071997137 36.0788586084025 0.573618678582417 0.566476761548378 -388.56907526588 97.3110106330075 -3.99306381403544 7.47351250541855e-05 PCDHA5 other 0.287321899501344 0.850336252866522 1 0.573618678582417 -3.99306381403544 4.67352498952899e-05 20.1108533895602 37.2368702250373 0.540079047138556 0.589376433945513 -404.449186013771 100.434371101879 -4.0269997370074 6.50143981877029e-05 PCDHA4 other 0.265736630904619 0.74324460008182 1 0.540079047138556 -4.0269997370074 5.80527851116979e-05 18.6923061836661 36.0448538134899 0.518584602406416 0.604273622839717 -388.469289854283 97.3961815693636 -3.98854743168369 7.61282655790328e-05 PCDHA2 other 0.325443913336179 0.865578379633603 1 0.518584602406416 -3.98854743168369 7.45202032074806e-05 18.8259303241482 36.4878488297811 0.515950677497399 0.606110723943189 -387.896996610012 98.5931908085818 -3.93431831781479 9.48987362453906e-05 PCDHA1 other 0.412245764143782 1 1 0.515950677497399 -3.93431831781479 6.17047922401579e-32 31.0466365084219 18.396085365898 1.6876762577964 0.0920519034596918 -336.16306432822 33.9731445593459 -9.89496464600133 2.52539784568097e-21 TRIM13 other 8.5967116548988e-28 3.90477014899192e-17 1 1.6876762577964 -9.89496464600133 0.506042905782023 0.640909520509415 8.21781769395097 0.0779902334632198 0.937864289625413 -32.6772776959279 29.785714776449 -1.09707884941426 0.273088765608341 PRSS1 other 1 1 1 0.0779902334632198 -1.09707884941426 1.94876581574852e-16 88.496274897046 16.6721704301792 5.30802364741029 1.63573027901444e-07 -76.1093286292862 36.2132525281907 -2.10169822691397 0.0360537980959745 SPIRE2 other 2.10505683417155e-12 1 0.00164947041335816 5.30802364741029 -2.10169822691397 2.5583620394549e-06 378.134176662235 73.5912976624689 5.13830016147523 3.93633462156548e-07 40.6337316466755 860.281640150525 0.0472330568853774 0.96234572085457 AARD other 0.0164528262757345 1 0.00388791770572022 5.13830016147523 0.0472330568853774 0.931394662046378 -0.407561272180023 1.12642474974976 -0.361818463479753 0.71763108810712 1.30708114887651 12.9139301305362 0.10121482272742 0.919417992702546 PKHD1L1 other 1 1 1 -0.361818463479753 0.10121482272742 0.192258224976723 0.673410957609393 1.19094132252345 0.565444279137551 0.57200388909222 6.30473342620787 3.4707796625127 1.81651791218677 0.0698391537781574 SLFN12L other 1 1 1 0.565444279137551 1.81651791218677 0.367466284552402 -1.72188865476001 1.66124533883341 -1.03650473202784 0.300434985171418 3.12196549859706 4.69947560084332 0.664322099690617 0.506770390273678 LINC02397 other 1 1 1 -1.03650473202784 0.664322099690617 2.37579540162113e-07 51.6603329499258 9.76131259598657 5.29235514608623 1.75056059731871e-07 0.113105473281666 31.447140882098 0.00359668542541666 0.997131577705533 SLC35B4 other 0.00167042174687981 1 0.00176228935332074 5.29235514608623 0.00359668542541666 0.000354734437645909 11.3880681991862 4.81079432814798 2.36719082596288 0.0182714475613796 -13.5643558576814 10.8992096103633 -1.24452656133744 0.213839772228642 SYCE1L other 1 1 1 2.36719082596288 -1.24452656133744 4.09088492069656e-13 67.4966873449918 14.5214489981571 4.64806834039478 4.20571530223223e-06 -69.4239211198806 31.7440268846124 -2.1869916306533 0.0291666670882333 TMEM231 other 3.92152228497972e-09 1 0.0388776322538348 4.64806834039478 -2.1869916306533 0.900033765392156 -0.520214405349099 8.97095790489172 -0.0579887243775198 0.953779021862465 -9.26290859856169 20.964151484061 -0.441845147207807 0.658777825940467 CCNI2 other 1 1 1 -0.0579887243775198 -0.441845147207807 0.0337221158223088 -0.348273875423132 1.16208825348697 -0.299696580167727 0.764525224357798 -5.51443099581172 2.25092842533267 -2.44984733132807 0.0146116933982948 TMEM240 other 1 1 1 -0.299696580167727 -2.44984733132807 0.000243576973626965 4.43131847709956 1.39572200597097 3.17492914645048 0.00158324757639662 -2.92730466072651 2.94962379476997 -0.992433226880309 0.321425840656923 C4orf47 other 1 1 1 3.17492914645048 -0.992433226880309 1.29822147570914e-27 188.922701841143 16.7277634928315 11.2939606016132 1.22509238670215e-26 -533.676988672893 185.854440616054 -2.87147827570818 0.0042499762107343 TRIQK other 1.73481335799012e-23 1 1.77148359117131e-22 11.2939606016132 -2.87147827570818 8.80969077694163e-14 57.2012353508703 7.66133432449674 7.46622362738722 3.31540183185963e-13 -44.2468002995604 35.3417695331177 -1.25196901242022 0.211121157905294 SDHAF1 other 8.68371219883137e-10 1 4.07794425318734e-09 7.46622362738722 -1.25196901242022 3.38365572064551e-14 301.350657650763 47.1517290464951 6.39108392724281 3.53919421509392e-10 -781.594158072886 216.556222182576 -3.60919741855274 0.000335449728306892 PSENEN other 3.3904230320868e-10 1 4.01026096512292e-06 6.39108392724281 -3.60919741855274 0.00057225935167339 23.8367308168551 6.23205787752268 3.82485709942259 0.000145947157713132 5.91956290022188 25.8869907336364 0.228669410096024 0.819211491570238 LINC00654 other 1 1 1 3.82485709942259 0.228669410096024 2.87051325465499e-15 304.411406510188 36.4584492402437 8.34954346259391 6.4430738550319e-16 -205.35972447691 379.917833077967 -0.540537207251248 0.589061667326716 ZBTB10 other 2.98992660604864e-11 1 8.37277447461395e-12 8.34954346259391 -0.540537207251248 2.32986176796147e-16 91.5598313631603 10.4348244663709 8.77444864149244 2.23498442277833e-17 77.70009000298 23.1733147322967 3.3529985200904 0.000855242476253839 C4orf46 other 2.51228994439286e-12 1 2.97677575269845e-13 8.77444864149244 3.3529985200904 0.184724437363696 0.808366315750643 0.958212118613906 0.843619382439015 0.399254294263036 -6.12473389799466 4.33676894891293 -1.4122804258525 0.158441303789379 SCGB2B2 other 1 1 1 0.843619382439015 -1.4122804258525 0.000120867586015595 285.910685461099 77.8205940046656 3.67397202653012 0.000262845712215676 -168.782886860809 197.432278442602 -0.854890032127538 0.392994689418731 LGR4 other 0.65050934793593 1 1 3.67397202653012 -0.854890032127538 8.60693906360685e-11 217.474205770911 54.7193350527479 3.97435761164262 8.03484080571171e-05 -280.001382658827 122.396583802351 -2.28765684433629 0.0225505591607371 PSMB10 other 7.44586298392629e-07 1 0.669784329564128 3.97435761164262 -2.28765684433629 3.72526011209982e-06 66.525490405122 13.2153215451776 5.03396683748475 6.54524529646001e-07 63.6829446892324 41.8597098977942 1.52134223683638 0.128756065416532 VIT other 0.0235846217697039 1 0.00636983272251489 5.03396683748475 1.52134223683638 1.82288211391225e-10 8.93101312236328 1.43861659453916 6.20805651503288 1.07285876408635e-09 -4.27490001537387 4.45962632577597 -0.958578074280704 0.33820191343637 SPDYE2 other 1.55455386674437e-06 1 1.19301894566402e-05 6.20805651503288 -0.958578074280704 6.58389483558094e-40 222.846343121702 24.0783276403668 9.25505900784009 5.66304384632136e-19 -199.228765857016 52.4619313488548 -3.79758733112987 0.000163458513105085 E2F4 other 9.64145559722473e-36 1 7.70117332661242e-15 9.25505900784009 -3.79758733112987 6.46022557479643e-10 155.933905933819 23.6149002687835 6.6031998508987 9.873186422456e-11 307.550226332062 216.34581695756 1.42156770422972 0.155745533260493 PDE7A other 5.34196052779917e-06 1 1.13758853959538e-06 6.6031998508987 1.42156770422972 0.000286381381444207 31.7979875851197 8.82622492861765 3.602671339365 0.000344283119169889 -25.4598163286542 30.4950724809079 -0.834882958372826 0.40415557024875 TMEM170B other 1 1 1 3.602671339365 -0.834882958372826 0.621091695931714 -0.642965914410787 3.29175324469298 -0.195326279528208 0.845211822170857 -11.0746595067903 11.3912128511264 -0.972210742747662 0.331385883119039 MUC12 other 1 1 1 -0.195326279528208 -0.972210742747662 5.98875594863463e-20 223.338893702165 35.9645763254955 6.20996871145786 1.05048695051956e-09 -384.535780223962 81.2440139392138 -4.73309677327943 2.82072871746989e-06 SNX2 other 7.08469828723476e-16 0.035092685974043 1.16845663506291e-05 6.20996871145786 -4.73309677327943 0.0017368682615303 10.2678924394951 4.8512610989442 2.11654088082989 0.0347548010196514 -33.2916454457322 15.4943972495322 -2.14862475187521 0.0321073032665083 SAP25 other 1 1 1 2.11654088082989 -2.14862475187521 2.76268015960333e-22 33.9084444386822 7.26754713915715 4.66573436531087 3.88898957759004e-06 -77.655384198457 12.8857016668853 -6.0264769591882 3.11868114860166e-09 NT5M other 3.42157937766873e-18 4.3193733908133e-05 0.0360509333842597 4.66573436531087 -6.0264769591882 2.22237071240829e-09 119.094252120361 22.3664228850224 5.32468927787786 1.47986369295792e-07 -129.751379832076 65.3188734334956 -1.98643015428278 0.0474850564784555 SARNP essential 1.78811947520371e-05 1 0.00149510628899539 5.32468927787786 -1.98643015428278 1.07800908117402e-43 1726.96872146817 161.406094714996 10.6995260898765 2.19753364992906e-24 -901.336437763516 351.952369099976 -2.56096141664977 0.010705953973214 ADGRG1 other 1.60278390188954e-39 1 3.13478175162381e-20 10.6995260898765 -2.56096141664977 1.08517150691895e-13 880.094070023056 150.584198747583 5.84453134753078 8.80229091422095e-09 -802.25282397726 316.259802922867 -2.5366891921226 0.0114715947959329 IPO7 essential 1.06607248839718e-09 1 9.44133723459339e-05 5.84453134753078 -2.5366891921226 6.74986565217529e-28 326.247945350248 51.998344460383 6.27419870259163 7.24175964977267e-10 -1174.89080185947 149.331649675349 -7.86766103778879 2.00123229207682e-14 PRR13 other 9.04684493361055e-24 2.99004116759197e-10 8.10570157599055e-06 6.27419870259163 -7.86766103778879 2.07820929998669e-08 46.644437157726 15.8939424308791 2.93473047109471 0.00348013500496579 -205.163685220745 48.7530191703778 -4.20822522813934 3.01326934826379e-05 TECPR1 other 0.000157798432147989 0.352492248359898 1 2.93473047109471 -4.20822522813934 0.179272930682887 -18.3017942197498 20.4113942421641 -0.896645961692488 0.370310394821121 -79.760084020789 43.5803784623718 -1.83018337230952 0.0677776817815083 MT1H other 1 1 1 -0.896645961692488 -1.83018337230952 0.0490390715517152 -31.3459400528095 39.0949427983265 -0.801790150058777 0.423029008625096 -193.393688932117 83.4208260308297 -2.31829026555845 0.0208082599959905 MT1A other 1 1 1 -0.801790150058777 -2.31829026555845 0.00128017794050076 5.26784584559817 21.1790887534475 0.248728635444274 0.803664742146086 -144.447985797201 41.8937893671708 -3.44795703561719 0.000608651354590094 C15orf59 other 1 1 1 0.248728635444274 -3.44795703561719 0.224717369854903 -97.0147046219565 90.7338733240194 -1.0692225633916 0.285449771623249 -334.995974239735 193.608024974278 -1.73027938425714 0.0841548881862601 MT1M other 1 1 1 -1.0692225633916 -1.73027938425714 0.205326919200458 65.4063567512776 38.7475647677056 1.68801206329722 0.0919831220638311 13.8376601981015 84.5480789440688 0.16366616924857 0.870054849052439 CFI other 1 1 1 1.68801206329722 0.16366616924857 0.600319974083824 -18.9676773710008 65.108896135552 -0.291322361409898 0.770915831181245 -212.074719756644 209.900554184331 -1.0103580744737 0.312772941014153 SAMD9 other 1 1 1 -0.291322361409898 -1.0103580744737 0.882173399963337 58.1941345502236 387.19415685659 0.150297037079973 0.880585573046697 598.15144116355 1195.47497645722 0.500346266499168 0.617032151974711 KRT6A other 1 1 1 0.150297037079973 0.500346266499168 4.5374028309771e-39 29.7107691293745 4.88078619366257 6.08729166787767 2.26529970987406e-09 -95.4119300260804 12.6326244634105 -7.55281931339243 1.99399530685002e-13 CNEP1R1 other 6.6168945484139e-35 2.95111305413802e-09 2.48412766184789e-05 6.08729166787767 -7.55281931339243 0.00563487030127815 51.9566950440118 410.137810847639 0.126681065899854 0.899239554565052 3998.4431147355 1271.65731852683 3.14427720147716 0.00175567909073795 KRT81 other 1 1 1 0.126681065899854 3.14427720147716 0.111952155429274 2.9190191435152 3.22368076126575 0.905492621536469 0.365608291891195 14.1371658431708 6.74787061894942 2.09505585413429 0.0366312659281321 EXOC3L4 other 1 1 1 0.905492621536469 2.09505585413429 5.69050759045921e-22 10.7052605542878 6.06828490004191 1.76413282016701 0.0782708189022552 -120.893140912139 13.8413592984543 -8.7341957032818 3.02945685130249e-17 ATP6AP1L other 7.00842914840956e-18 4.61628635001473e-13 1 1.76413282016701 -8.7341957032818 2.29135497448502e-25 434.223450205634 46.3866737248572 9.36095251798464 2.09072213198893e-19 -207.484652340424 95.3732636687416 -2.1755012291608 0.0300239665682662 CCDC85C other 2.97555356986624e-21 1 2.85801715442887e-15 9.36095251798464 -2.1755012291608 0.703753108135296 4.50531805030776 6.13371809914329 0.734516646752486 0.46295937571552 -1.90121999196782 12.6820797384739 -0.149913896708916 0.880889686807177 C2CD4B other 1 1 1 0.734516646752486 -0.149913896708916 5.74564550818863e-05 29.1442439846151 17.8707891173368 1.63083139716207 0.103507887581033 -212.813463552595 59.8222992914055 -3.55742701422995 0.000407387270786922 RGL3 other 0.3222732565543 1 1 1.63083139716207 -3.55742701422995 3.30566335013686e-34 602.844629576693 74.2352689663705 8.12073072503839 3.17227415330608e-15 -891.88209401871 151.221730741822 -5.89784344910984 6.50615754596859e-09 NAP1L4 other 4.69007516117418e-30 8.94076169967004e-05 4.07161387576835e-11 8.12073072503839 -5.89784344910984 3.22012383849466e-27 186.552755644839 29.1149865088582 6.40744777910442 3.22537187885282e-10 -326.437742646248 53.2073413521783 -6.13520116492127 1.64602113439514e-09 TMEM256 other 4.2840527547333e-23 2.29471806346027e-05 3.66015200812218e-06 6.40744777910442 -6.13520116492127 1.78969197159815e-17 6.11184701136576 0.736207023177549 8.3018048170559 8.80632897732669e-16 -0.0420518699326045 1.57793631885374 -0.0266499157349722 0.978749125774575 CHKB-AS1 other 1.99085334920578e-13 1 1.14156442533086e-11 8.3018048170559 -0.0266499157349722 2.44160801369832e-05 32.7486419906853 25.2120328065694 1.29892905669042 0.194539550817268 -191.194118280773 54.0157138190835 -3.53960180774701 0.000436390385657867 CPT1B other 0.142858484881489 1 1 1.29892905669042 -3.53960180774701 1.10118057943846e-18 806.54447070287 91.2683409517837 8.83706729290676 1.40245774566117e-17 -438.428795308064 274.596139854724 -1.59663131295296 0.11093618396882 HMGN1 other 1.26371483296357e-14 1 1.87354330242875e-13 8.83706729290676 -1.59663131295296 1.32143690688403e-17 23.3303356544035 12.4340027119236 1.87633348608094 0.0611619106294564 -195.338089830997 26.509553881222 -7.36859211989096 6.70470019343573e-13 DENND6B other 1.47604502498946e-13 9.86663680466002e-09 1 1.87633348608094 -7.36859211989096 1.19056233462674e-27 1268.24916054479 122.222601155108 10.3765518697749 4.29550502131031e-23 -2210.028672385 730.141729835503 -3.02684887341381 0.00259108298126974 EIF3CL essential 1.59178184139595e-23 1 6.06911904460933e-19 10.3765518697749 -3.02684887341381 2.16765429409696e-09 216.977170604608 37.4402397302767 5.79529330388195 1.15696275850762e-08 -277.230081105704 211.713290297531 -1.30945998107204 0.190932373184981 LCMT1 other 1.74539523760687e-05 1 0.000123552052981029 5.79529330388195 -1.30945998107204 0.00668633998906049 11.2042068445087 3.536298103068 3.16834342522997 0.00161969144419662 11.0114740313388 10.1855526171138 1.08108754087995 0.280139847916672 MFSD2B other 1 1 1 3.16834342522997 1.08108754087995 2.19832622062911e-22 34.9583864436329 5.62380003990994 6.2161503246109 1.01873885456713e-09 -46.7594650970759 10.9878519472185 -4.25556016969385 2.45787091125184e-05 CDPF1 other 2.72746334193453e-18 0.289315984963454 1.13416196678959e-05 6.2161503246109 -4.25556016969385 3.65307512017826e-26 42.116316066383 7.2046372449437 5.84572333547269 8.67588346745887e-09 -91.9893211545534 14.3715433331304 -6.40079628347866 3.32705781472086e-10 LIN52 other 4.79685294030607e-22 4.70978304251885e-06 9.30922296058337e-05 5.84572333547269 -6.40079628347866 6.67807581131511e-14 22.3019057372966 3.97444479856977 5.61132607636721 3.22293751568634e-08 -52.6691823614202 12.0620141684669 -4.36653295426486 1.51552601271912e-05 SMIM11A other 6.61596970626988e-10 0.180984116438917 0.000337570475392987 5.61132607636721 -4.36653295426486 0.102327664214288 6.98897448350312 3.76461912853874 1.85648912808238 0.063924291439923 13.0264541659891 7.37158286590046 1.76711764663828 0.0777691589012995 DPF3 other 1 1 1 1.85648912808238 1.76711764663828 0.000902706064157637 3.48098673178856 1.21247783051635 2.87096938531746 0.00425123018106275 -1.83136429624461 2.36038096149196 -0.775876575062289 0.43815841643969 CYP2D7 other 1 1 1 2.87096938531746 -0.775876575062289 7.27028508287122e-28 81.6414043304424 8.71537235725963 9.3675176439751 2.10745135231532e-19 -185.650530288303 35.9368143175522 -5.16602636638352 3.38876904258564e-07 ETFRF1 other 9.74290903955572e-24 0.00438710040253137 2.8806752534798e-15 9.3675176439751 -5.16602636638352 6.68866598853894e-13 21.9444043024933 8.7869606392165 2.49738279292555 0.0128052236240687 -91.1324116466242 16.434499724047 -5.54518927724214 4.5828359142749e-08 C17orf107 other 6.35958362190283e-09 0.00061350424384398 1 2.49738279292555 -5.54518927724214 2.57473358388603e-05 172.739230576774 41.9354309950705 4.11917146140884 4.3988391824201e-05 -165.965708566973 126.9665301848 -1.30716109454523 0.191714329815607 ITSN1 other 0.150390188634783 1 0.375616877786852 4.11917146140884 -1.30716109454523 1.23810709793207e-16 700.040924795376 83.908232018296 8.34293498929562 5.93082030474482e-16 -265.941470292647 445.233022462387 -0.59730850335818 0.550548595895361 ITPRIPL2 other 1.34532717261299e-12 1 7.71599721647301e-12 8.34293498929562 -0.59730850335818 2.09317427784434e-14 21.2708501487517 12.5682517160173 1.69242712744554 0.0911361097157691 -206.263012708339 29.9426226244666 -6.88860876668161 1.55928401690224e-11 DENND1C other 2.11201284634494e-10 2.25784325647445e-07 1 1.69242712744554 -6.88860876668161 0.582284066947569 -3.83891395713934 9.46933175868143 -0.405404948835998 0.685343161499658 31.9949877096621 38.934660680901 0.821761051724201 0.411581718998874 SLCO1B7 other 1 1 1 -0.405404948835998 0.821761051724201 1.34586771015783e-24 57.2875163429922 7.56915238637867 7.56855106340387 1.65341892750447e-13 -149.017687187582 23.0003439647123 -6.4789329853592 2.09140259453962e-10 CRYZL1 other 1.72917083401078e-20 2.97251050761917e-06 2.04891673496354e-09 7.56855106340387 -6.4789329853592 0.00500787760275806 12.5383308330737 3.9485726201689 3.17540844228852 0.00158083969530822 -1.62785623209722 16.6210106740406 -0.0979396658856419 0.922016211032881 RP9P other 1 1 1 3.17540844228852 -0.0979396658856419 2.44684182989597e-10 117.761300550185 22.1938159441788 5.30604114436086 1.64457343017452e-07 -355.250402536448 106.418023663874 -3.33825408803422 0.000901852164278443 C5orf51 other 2.07369845083683e-06 1 0.00165805893230196 5.30604114436086 -3.33825408803422 1.06396879097888e-06 26.8864866198272 15.6683416459479 1.71597525937153 0.0867810924911791 -106.003514075364 29.1046466131679 -3.6421508731669 0.000298347400820353 CATSPER2P1 other 0.00708071230396443 1 1 1.71597525937153 -3.6421508731669 8.35863807259864e-24 13.3315132454154 1.40711416748756 9.47436501845419 8.21879048304857e-20 -8.8507538398279 4.61569667803505 -1.9175336806568 0.0556944691561646 LOH12CR2 other 1.06071117141277e-19 1 1.12761805427426e-15 9.47436501845419 -1.9175336806568 0.131072948419487 -9.54972826837992 6.39924175882863 -1.49232184503809 0.136196615033196 -32.1880990846803 19.1440919965828 -1.68135940270376 0.0932692033320977 CYS1 other 1 1 1 -1.49232184503809 -1.68135940270376 1.58243791924244e-23 34.7967040063038 12.1885907324656 2.85485867645216 0.00447016228727764 -252.234106550684 29.6835836481197 -8.49742772101784 1.87405112562562e-16 PLPP6 other 2.0005180175063e-19 2.84181112689869e-12 1 2.85485867645216 -8.49742772101784 3.83749409642295e-05 1.18829871267104 1.40916450711949 0.843264719390408 0.399452398970353 -28.4931218288155 6.6386176549662 -4.29202633887199 2.09745086165349e-05 TTC23L other 0.220233786193713 0.248233309476691 1 0.843264719390408 -4.29202633887199 0.00321986360246224 6.78112797418997 4.4635642855615 1.51921817192713 0.129286410859898 -19.1116597422346 9.6242465668972 -1.98578243080031 0.047557181189461 C1QTNF9B other 1 1 1 1.51921817192713 -1.98578243080031 0.0311825913718731 6.34251404352333 3.14568466140163 2.01625869285235 0.044266646301746 -3.22473974192268 6.34407219885349 -0.508307541409358 0.611444881687692 KRTAP5-2 other 1 1 1 2.01625869285235 -0.508307541409358 1.19310731682074e-09 28.2767402220831 4.92019983452407 5.7470714956882 1.51504578097944e-08 -29.6250816411163 18.1443045279321 -1.63274825968172 0.10310165654741 C1RL-AS1 other 9.72501773940588e-06 1 0.000161079667433734 5.7470714956882 -1.63274825968172 1.13437676314542e-16 109.434551070227 18.7986545357955 5.82140338085615 9.99014526219113e-09 -326.443578333852 66.5941501197595 -4.90198580125721 1.25473693454643e-06 ZNF316 other 1.23454223133117e-12 0.0158601806216451 0.000106924524741232 5.82140338085615 -4.90198580125721 2.15938232074181e-13 10.6141418687855 2.23097191547198 4.75763132434592 2.51301940764679e-06 -43.2290055095002 10.1771910944278 -4.24763621989655 2.54124316944444e-05 SRRM2-AS1 other 2.09632835697615e-09 0.298773959431583 0.0236073043154339 4.75763132434592 -4.24763621989655 5.23390297000133e-08 38.9262654582483 8.6145115263888 4.51868516734879 7.6384779303251e-06 -79.762290946336 39.7787200846899 -2.00514975787356 0.0454419245417887 CEMP1 other 0.000387256480750398 1 0.0694108489528641 4.51868516734879 -2.00514975787356 3.74947458569514e-29 668.059520630648 55.4756644052751 12.042388816656 9.10139519430056e-30 586.262917631585 254.818959797492 2.3007036764356 0.0217864433705085 RNPS1 other 5.091786487374e-25 1 1.33653988428304e-25 12.042388816656 2.3007036764356 0.00378116456578085 104.989866589845 34.0911453343302 3.07968141170426 0.00217926343141607 -27.8715621326987 91.6363168361341 -0.304154107181535 0.761129416057872 NYNRIN other 1 1 1 3.07968141170426 -0.304154107181535 0.00590265624620703 28.7481592273264 21.5005527140471 1.33708931159449 0.181761714845684 -244.647496574178 82.3251367406732 -2.97172293007937 0.00309454128242017 DNAJC19 other 1 1 1 1.33708931159449 -2.97172293007937 0.0308562267730891 -7.25172556910231 7.4024329179648 -0.979640835583023 0.327707047306875 -40.0356485940638 15.1647376029416 -2.64004888461096 0.00853185050135919 DOK6 other 1 1 1 -0.979640835583023 -2.64004888461096 1.15793761433675e-33 1263.05688581004 111.609285454117 11.3167724412077 8.52625465855076e-27 -1384.75732737194 505.421802062224 -2.73980529079245 0.00635050973069205 JPT2 other 1.63558688025066e-29 1 1.23383431163888e-22 11.3167724412077 -2.73980529079245 0.493021316664284 -8.43144284407847 13.1356469100732 -0.641874960692854 0.521225741212007 18.5740967817189 28.694758432273 0.64729929075927 0.517712316591433 SERPINB11 other 1 1 1 -0.641874960692854 0.64729929075927 0.0151816468264931 -6.28250001719953 12.6736612015107 -0.495713110624311 0.620298140411817 66.717608862835 27.7217223926904 2.40669060593533 0.0164319246285929 SERPINB4 other 1 1 1 -0.495713110624311 2.40669060593533 0.00114494608280104 560.571468181878 151.850339717601 3.69160496594466 0.000245348647033243 416.204910995721 331.651797349866 1.25494544073482 0.210038408979891 SERPINB5 other 1 1 1 3.69160496594466 1.25494544073482 0.139267355902578 11.1812510450359 8.70227025870633 1.28486598469513 0.199408959554567 -52.4164196484494 39.856363420598 -1.31513302142765 0.189042611343995 ZDHHC11B other 1 1 1 1.28486598469513 -1.31513302142765 3.29576311337127e-21 -2.84322929748425 3.0552380235654 -0.930608114835603 0.352472153846186 -55.2940627306416 5.97790590833342 -9.24973788121349 5.20908240385005e-19 CFAP99 other 3.99874938545336e-17 7.99177422398675e-15 1 -0.930608114835603 -9.24973788121349 5.81100867113666e-09 54.4657966428778 20.552724533383 2.65005238378061 0.00828299783753933 -153.580956319357 39.6310536694362 -3.87526805621623 0.000119549150505978 HERC2P9 other 4.56164180684228e-05 1 1 2.65005238378061 -3.87526805621623 0.196467296713549 76.913213609652 64.22387647479 1.19757974496982 0.231622109818766 481.233049786441 285.753125479646 1.68408674088403 0.0927604323060208 HBA1 other 1 1 1 1.19757974496982 1.68408674088403 0.0418367999441437 1.20745147117505 23.4264168364729 0.0515423028456981 0.958912631993903 -96.3942096344868 43.4058017216585 -2.22076786537935 0.0267847162324592 ATP10A other 1 1 1 0.0515423028456981 -2.22076786537935 2.12566385882913e-18 23.4050582753768 2.50923931058047 9.32755125295821 2.71433703111977e-19 -3.94508884626101 9.92511358150796 -0.397485511260176 0.691165383497385 ANKUB1 other 2.42431963099463e-14 1 3.70398431266603e-15 9.32755125295821 -0.397485511260176 5.32827041150308e-13 10.0613762889546 1.5530484558497 6.47846900787769 2.09434578687906e-10 -0.390384354877006 3.04867080117879 -0.128050675306124 0.898156719807258 TSSK2 other 5.08263714553279e-09 1 2.38755419704213e-06 6.47846900787769 -0.128050675306124 2.49710847659833e-06 259.582978443607 52.1828156845811 4.97449160299544 8.77783619617847e-07 72.5106389353421 184.978014361115 0.391995984959524 0.695214136690446 HCP5 other 0.0160813785892932 1 0.00847587863102994 4.97449160299544 0.391995984959524 0.00464723456351318 1.54667495725166 1.19030431046569 1.29939456965131 0.194355930691831 -10.4431962118404 4.28211583667452 -2.43879348671485 0.0150533733246673 HCG27 other 1 1 1 1.29939456965131 -2.43879348671485 0.815235923741858 -3.95952728346578 7.6479036858381 -0.517727137541988 0.604858742921869 -11.7002809478055 25.5817112629954 -0.457368970649367 0.647588127112662 COL6A6 other 1 1 1 -0.517727137541988 -0.457368970649367 1.84393542688205e-17 259.671386517528 34.3290068489806 7.56419746309201 1.6955334719262e-13 -75.2600807480564 72.5118416785424 -1.03790055535615 0.299781734990466 RAB12 other 2.05064058823553e-13 1 2.10059641836937e-09 7.56419746309201 -1.03790055535615 0.212769288264778 11.2650510588465 9.51700095141353 1.18367657168022 0.237067762376604 -16.7744890810993 22.6687565471137 -0.739982762011493 0.45963565117001 TMEM200C other 1 1 1 1.18367657168022 -0.739982762011493 9.42909727369011e-09 7267.86202482365 1175.4667150436 6.1829585915192 1.23597668597608e-09 8462.61205213401 4754.65514303123 1.77985822263838 0.0756572928506579 HLA-A other 7.30377874820036e-05 1 1.37106893775327e-05 6.1829585915192 1.77985822263838 9.06550154048446e-12 577.707275263824 86.7485133097062 6.65956398816099 6.74135181604948e-11 -477.579435204237 287.451346318526 -1.66142702520179 0.0972049125612831 HACD2 other 8.23600814953013e-08 1 7.80176645671407e-07 6.65956398816099 -1.66142702520179 1.292974203385e-05 7.64977739312312 14.9283445466777 0.512433067792876 0.608555557532028 -234.282516804032 50.5093113925079 -4.6384025112404 4.40115741272311e-06 CFAP44 other 0.077837047043777 0.0542266604821614 1 0.512433067792876 -4.6384025112404 9.46432265367647e-06 15.7515405194936 3.26283966375754 4.82755579272131 1.79858169455684e-06 0.662568767584395 11.4684095808234 0.0577733785068412 0.953950358038365 LNP1 other 0.0577134395421191 1 0.0170397629742315 4.82755579272131 0.0577733785068412 0.784359735842005 19.4926213612947 30.625190965193 0.636489789841605 0.524751440915494 32.8373445164173 63.1917772044732 0.519645845853705 0.603542723304264 VGLL3 other 1 1 1 0.636489789841605 0.519645845853705 0.0608273646836822 0.316771259705367 3.93800418655435 0.080439543661972 0.935918042028106 -14.8991683683235 7.3585457510202 -2.02474359369959 0.0433945767828837 PRSS50 other 1 1 1 0.080439543661972 -2.02474359369959 8.0056852535882e-08 1.27659997380444 1.16212554594985 1.09850435544898 0.272475675097744 -11.822956185931 2.38990197359258 -4.94704649670562 1.00903686563848e-06 ZCWPW2 other 0.000582813886461221 0.0128097230092804 1 1.09850435544898 -4.94704649670562 3.86723160517699e-11 220.291769015429 44.7120466347622 4.92689969696354 1.11093245984952e-06 -455.181402451022 121.516724521394 -3.74583337597191 0.000199019060658045 ANKRD28 other 3.40780449048197e-07 1 0.0106638406820956 4.92689969696354 -3.74583337597191 6.988317133149e-29 51.4286801588113 4.43908514288777 11.5854232355082 6.8753301839326e-28 -8.90935747752179 12.792812702801 -0.696434606251298 0.486454700315573 COLQ other 9.46637438856364e-25 1 1.00111682808243e-23 11.5854232355082 -0.696434606251298 1.29253267259631e-48 111.511827265835 7.36327143752622 15.1443320013337 1.78904642691306e-43 -60.4356139234257 21.2916788852493 -2.83846164734782 0.00470279790872351 METTL6 other 1.94720047126634e-44 1 2.72006618747861e-39 15.1443320013337 -2.83846164734782 1.11886974774544e-24 109.756252463945 10.2534797385699 10.7042931046211 2.2197657723198e-24 -20.163560471171 26.3947243091284 -0.763923890055469 0.445246249216956 THUMPD3-AS1 other 1.43964970442406e-20 1 3.16627389763697e-20 10.7042931046211 -0.763923890055469 0.978911830927404 38.6270385183697 266.457828143766 0.144964922920293 0.884798788774955 -518.638924294367 3407.08895233926 -0.152223476272399 0.879073981129841 RNVU1-7 other 1 1 1 0.144964922920293 -0.152223476272399 0.850067584640076 -10.7186039666858 24.8463669343803 -0.431395221482234 0.666360849869598 -31.9299270957085 61.9784082094139 -0.515178237360065 0.606648672944077 SNORA57 other 1 1 1 -0.431395221482234 -0.515178237360065 0.696111899208206 -328.298126118371 693.47633331651 -0.47340927201986 0.636110780240303 -917.626831432392 1078.13669013212 -0.851122904758899 0.395074880570463 RNU1-1 other 1 1 1 -0.47340927201986 -0.851122904758899 0.694865573274981 -319.167529110867 664.740690304668 -0.480138396469433 0.631321634451311 -904.909998903548 1061.20125581426 -0.852722321939972 0.394187889936999 RNU1-2 other 1 1 1 -0.480138396469433 -0.852722321939972 1.0078512569322e-17 5.59533621582354 0.782702189953995 7.14874225170167 2.88153362024391e-12 -1.81538064805409 1.72230231701318 -1.05404296918228 0.292338144507766 SNORA25 other 1.1295996887696e-13 1 3.46763755860152e-08 7.14874225170167 -1.05404296918228 0.211417999563715 2.77444125903985 5.60226295863636 0.495235814442235 0.620636629776684 -14.4055469830651 12.3275373418128 -1.16856648523011 0.243097804771843 SNORA8 other 1 1 1 0.495235814442235 -1.16856648523011 0.693453056196555 -329.779923224589 680.859065954194 -0.484358569511617 0.628325646300182 -907.801716350769 1061.35788280869 -0.855321028895963 0.392748613295695 RNU1-4 other 1 1 1 -0.484358569511617 -0.855321028895963 0.624440082054056 -1.44829245815906 4.7502560718502 -0.304887238972563 0.760570826889238 -11.7984938257256 12.1837199578633 -0.968381895392373 0.333292061728713 SNORA7A other 1 1 1 -0.304887238972563 -0.968381895392373 0.697907405608282 -322.44131681766 680.763542935915 -0.473646569596066 0.635941285991651 -935.16356155579 1103.51296352749 -0.847442297883342 0.397119948791845 RNU1-3 other 1 1 1 -0.473646569596066 -0.847442297883342 5.19110670372065e-17 3.45100651303164 0.677806677283963 5.0914318620468 4.90220027448549e-07 -4.62797379207205 1.27974680378893 -3.61631986762544 0.000326569257380892 MIR621 other 5.70346893537788e-13 1 0.00481101934938006 5.0914318620468 -3.61631986762544 3.68083962536643e-16 4.19535096743546 0.818288569422335 5.12698224588073 4.13133554506352e-07 -6.94536324763273 1.82884145775643 -3.79768471355254 0.00016292172871333 MIR130B other 3.94438774254266e-12 1 0.00407680191586869 5.12698224588073 -3.79768471355254 0.00450420057536937 1012.77860490421 360.649714603139 2.80820575726416 0.00516010834533774 -556.454353996457 843.164367829395 -0.659959522991903 0.509558096203285 GPX3 other 1 1 1 2.80820575726416 -0.659959522991903 0.146802652137762 -149.461743585507 124.308594255436 -1.20234441134766 0.229754163479331 -493.919289421049 257.846704039695 -1.91555401594356 0.0559467831467961 DIO2 other 1 1 1 -1.20234441134766 -1.91555401594356 2.3514621723931e-08 196.390370470862 57.1885569302129 3.43408508647135 0.000640923624905874 -455.223615953298 148.386062915958 -3.06783269943031 0.0022659609830349 SELENOH other 0.000177911627963262 1 1 3.43408508647135 -3.06783269943031 0.186980531415014 25.9676169061511 62.2351806108149 0.417249803909762 0.676661224366104 -219.364755578145 140.047517375098 -1.56635947348218 0.117849190626937 DIO1 other 1 1 1 0.417249803909762 -1.56635947348218 1.04170249264104e-08 -10.5692159876209 8.69208497189281 -1.21595865914772 0.224526114916203 -84.3134727538088 14.5174508336274 -5.80773261918064 1.07586122540628e-08 AKR7L other 8.04194324318882e-05 0.000146887333104719 1 -1.21595865914772 -5.80773261918064 2.38016709052095e-18 612.442361637709 65.9870873584378 9.28124556113472 4.05928677974537e-19 159.913198556993 361.948111973668 0.441812495401624 0.658802095738048 STK38L other 2.71101031610336e-14 1 5.52671895062333e-15 9.28124556113472 0.441812495401624 9.63080134908825e-36 83.5612648734207 30.0645081962811 2.77939902851154 0.00563294747986783 -588.186040717818 56.0640350640366 -10.4913255003139 1.3693283864157e-23 SACM1L essential 1.38124952948624e-31 2.12738858113544e-19 1 2.77939902851154 -10.4913255003139 6.19683618492576e-11 228.183444208501 50.5977318771706 4.50975638122341 7.96669226785216e-06 -484.859920820664 123.371081402668 -3.93009378946873 9.59483035113961e-05 TSN other 5.40426083687376e-07 1 0.0723216324075619 4.50975638122341 -3.93009378946873 8.71575186547114e-15 57.3307604920032 19.7672101999985 2.90029599078212 0.00388167988628023 -378.948751225197 56.425344567735 -6.7159315397763 4.79389606516113e-11 SLC48A1 other 8.92667306061554e-11 6.88834925603003e-07 1 2.90029599078212 -6.7159315397763 3.95554834407425e-07 2.92258681403629 0.587398844001593 4.9754725326432 8.84074528493704e-07 -3.85727875874749 3.52008456851612 -1.09579150263811 0.273673400411866 MIR762 other 0.00273407501542412 1 0.00853573957260671 4.9754725326432 -1.09579150263811 2.77862930366581e-08 7.25370659271039 3.54875754424244 2.04401301082936 0.0414350453179215 -40.2102746027183 8.78543079729962 -4.57692690665524 5.85605620245184e-06 PRR22 other 0.000209369718031219 0.0716781279180105 1 2.04401301082936 -4.57692690665524 7.67941844115394e-54 33.2550185573373 2.06029167162995 16.1409275275225 3.56957183319158e-48 -12.2262904421133 7.61520564148384 -1.60551021439402 0.108961874787352 TAS2R14 other 1.16911466348128e-49 1 5.46073099041648e-44 16.1409275275225 -1.60551021439402 0.828723288922195 -5.10847160435419 17.0307651159633 -0.299955496395516 0.764325682221834 49.284528942227 104.766628338591 0.470422020101158 0.638242080167931 SNORD17 other 1 1 1 -0.299955496395516 0.470422020101158 1.73457329970426e-19 11.2085043464655 1.16678796897796 9.60629064103529 2.68392270195515e-20 6.9910635972648 4.33900696695958 1.61121280756172 0.107709130097968 SNORD86 other 2.03257299259346e-15 1 3.70193458280674e-16 9.60629064103529 1.61121280756172 1.05308081782742e-08 -3.97608505022737 14.3907673520792 -0.276294165067779 0.782427458974134 -185.864160113647 31.3067132886367 -5.93687872629892 5.19081852670418e-09 LINC01089 other 8.12767775199204e-05 7.15190976609302e-05 1 -0.276294165067779 -5.93687872629892 0.0217308601495388 -2.3298575233906 1.76551086618918 -1.31965062804714 0.187534624578655 7.44410739620762 4.12746127304775 1.80355596424793 0.0718818386106694 CTAGE1 other 1 1 1 -1.31965062804714 1.80355596424793 0.00886885640569308 13.3890224515441 5.42849182082954 2.46643504189679 0.0139526040896481 42.4780461616972 15.2959344877896 2.77708081161086 0.00567340351426391 C17orf51 other 1 1 1 2.46643504189679 2.77708081161086 2.18724019046643e-05 -13.7396548992233 19.6835778198596 -0.698026295065155 0.485459548581493 -199.145109551434 42.9990803616992 -4.63138066852284 4.5509099447617e-06 EWSAT1 other 0.128653468003235 0.0560217014200165 1 -0.698026295065155 -4.63138066852284 0.000562082491086376 10.6204614116613 11.2711909861073 0.942266121189137 0.34650694481043 -86.3726408459171 26.2668446735624 -3.28827622500282 0.00107829233361066 RNF208 other 1 1 1 0.942266121189137 -3.28827622500282 0.000447890314637452 12.7776683098527 3.26778928862948 3.9101873411219 0.000103858872534657 15.7063038881945 19.5955711040919 0.801523150550828 0.423178162062226 MAP10 other 1 1 0.856731839538388 3.9101873411219 0.801523150550828 1.8313894033851e-07 5.30538203022539 2.21865185338891 2.39126387590807 0.0171415960496899 128.310234129722 24.6936035131447 5.19609193779356 2.91822760541737e-07 POU5F1B other 0.00130010333746309 0.00378669214078958 1 2.39126387590807 5.19609193779356 3.13608060482181e-08 5.14586726741598 1.16726553363252 4.40848043495475 1.26262005839378e-05 48.0361221769716 10.6820001716703 4.49692205626133 8.48889322391127e-06 PTTG3P other 0.000235425571003973 0.102978763699268 0.112840354618652 4.40848043495475 4.49692205626133 5.66010843651596e-15 101.659851086864 14.6847854421434 6.92280125490384 1.27736953279432e-11 -223.503745989453 64.6697550089923 -3.45607843973392 0.000591813709823235 ZNF580 other 5.83726983057891e-11 1 1.51112815729568e-07 6.92280125490384 -3.45607843973392 2.77640902666239e-14 49.7893193364289 6.64077548259964 7.49751583484314 2.6652022253091e-13 -57.0552440445767 29.1268826511687 -1.95885171536843 0.0506415467364101 ZNF611 other 2.78834758547704e-10 1 3.28752694491877e-09 7.49751583484314 -1.95885171536843 2.63684066568045e-13 316.562226665806 43.9887629538018 7.19643393923735 2.07455806923406e-12 -146.063717472855 150.475768360514 -0.970679326407636 0.332141760132376 NUP62 other 2.55272544844524e-09 1 2.5056512360209e-08 7.19643393923735 -0.970679326407636 2.0817166270958e-14 13.7430249079757 1.77212142019775 7.75512600397447 4.41252536669047e-14 -21.2208441379393 10.5926792761951 -2.00335001038206 0.0456379939913437 SPHAR other 2.10066024840237e-10 1 5.54213186056324e-10 7.75512600397447 -2.00335001038206 0.115066417785311 137.789688073276 107.347379187765 1.28358688508141 0.199843251607236 -1195.46224428059 759.225952331421 -1.57458032172053 0.115945588186633 DENND1B other 1 1 1 1.28358688508141 -1.57458032172053 0.103477985882694 1.33892616273958 0.866533746552689 1.54515178210451 0.122891061544431 -8.07004791653097 5.92819639795839 -1.36129901487579 0.173982790912611 C1orf220 other 1 1 1 1.54515178210451 -1.36129901487579 2.70558118306869e-07 482.242538713106 86.5182120808919 5.573884701434 3.94174072440059e-08 78.6647953411239 718.531434467791 0.109479963669773 0.912862559935669 SFT2D2 other 0.00189390682814808 1 0.000411320644591201 5.573884701434 0.109479963669773 1.35567203184326e-33 93.6899299879391 17.2933292005004 5.4176919262734 9.07366630181974e-08 -289.585409774573 36.2978098636496 -7.97804084770906 8.81687788970844e-15 FGFR1OP other 1.91366664014995e-29 1.3213854893306e-10 0.000929597112621432 5.4176919262734 -7.97804084770906 0.138352419862467 -2.08024274351465 1.2047611127533 -1.72668483527044 0.0847972439862919 -12.5855655945094 13.191222691356 -0.954086356434307 0.340467609022194 RPL31P11 other 1 1 1 -1.72668483527044 -0.954086356434307 9.68039937420894e-23 128.797293383908 33.1751548777869 3.88234188682409 0.000116215081515967 -477.347037082826 71.5027541518078 -6.67592518281699 6.09118728698415e-11 SCAF8 other 1.20869466586373e-18 8.73841728190746e-07 0.953893389083057 3.88234188682409 -6.67592518281699 3.78310504499505e-08 34.9809567709567 5.96845075881277 5.86097769497474 7.98909816618403e-09 51.0194800889506 58.5234937431242 0.871777756688438 0.383714920017141 CFAP45 other 0.00028248445370978 1 8.58109034029827e-05 5.86097769497474 0.871777756688438 0.422879565302259 -32.967098157058 32.7723819080379 -1.00594147381678 0.314892601205133 -256.225257013751 306.610926432272 -0.835669035005344 0.4037093526393 ACKR1 other 1 1 1 -1.00594147381678 -0.835669035005344 4.90817110797881e-05 33.7443203457305 13.573916634234 2.48596784959073 0.0132281549117152 -137.954772232535 49.3110675248341 -2.79764318959547 0.00533562773375382 ZNF254 other 0.277753403000521 1 1 2.48596784959073 -2.79764318959547 5.08468567260585e-14 40.2821554372898 5.17691715107427 7.78110876835855 3.70034968752936e-14 -50.483056639401 24.4518225944526 -2.06459279034906 0.0394402219710441 TCTEX1D2 other 5.05671990140652e-10 1 4.65615001181819e-10 7.78110876835855 -2.06459279034906 1.5509332603366e-07 9.80795986707489 1.76118598546968 5.56895180179351 4.03232841157468e-08 -7.50109102072978 7.13294386124106 -1.05161223285229 0.293444394878136 CRYGS other 0.00110798672118447 1 0.000420531530043124 5.56895180179351 -1.05161223285229 2.17854163200927e-06 338.123378167661 743.640711634735 0.454686480819977 0.64952492517884 -7485.38911147961 1637.88056167043 -4.57016786611442 6.0971620974266e-06 CRIP1 other 0.0141147712337881 0.0745560981273325 1 0.454686480819977 -4.57016786611442 0.631461932400935 0.142578177675781 1.92810179818116 0.0739474325527207 0.941079246583422 23.0707153342418 24.3051764978364 0.949209948600681 0.342933018341845 LINGO4 other 1 1 1 0.0739474325527207 0.949209948600681 1.40694878379194e-137 71.6265550477105 2.07972537421973 34.4403909937307 6.88279772128949e-139 51.0054694133713 7.62494705486147 6.6892883381861 5.57221267667223e-11 FAM24B other 2.20300040566141e-133 7.99723963355998e-07 1.07784612315393e-134 34.4403909937307 6.6892883381861 1.56668080192411e-13 293.438238818775 37.2942233062613 7.86819546847915 1.99951686684946e-14 -47.3955575033131 140.373720377241 -0.337638393966778 0.73576789162709 TRIM59 other 1.53033380731947e-09 1 2.52731977429362e-10 7.86819546847915 -0.337638393966778 0.00278506080871773 53.1204944198463 15.4071291162675 3.44778667193484 0.000610127853815633 -17.7034811458218 189.812273690925 -0.0932683688023713 0.92572560640137 MLLT11 other 1 1 1 3.44778667193484 -0.0932683688023713 0.006724413333477 6.35334486949212 4.66259306595331 1.3626204945666 0.173565966532004 -32.5739216461126 14.439736811101 -2.25585286437288 0.0244762186327434 ASIC3 other 1 1 1 1.3626204945666 -2.25585286437288 0.177655734369876 -14.4441624022815 8.0823212544114 -1.78713044775321 0.0744720247677295 -27.4049003937407 25.0513694267687 -1.09394819607973 0.274460959092827 GIMAP1 other 1 1 1 -1.78713044775321 -1.09394819607973 1.75860504963842e-13 24.4671773418001 9.16761110945384 2.66887164493366 0.00783870020615972 -94.216791919763 20.1682101906509 -4.67154948451687 3.77505073734603e-06 CFAP206 other 1.71411234188257e-09 0.0466332017584355 1 2.66887164493366 -4.67154948451687 2.60710263807433e-11 13.9037672546853 5.42832533662377 2.56133639612193 0.0107112886664497 -69.1902076099828 12.6095044255093 -5.48714725616097 6.42226811190625e-08 CCDC183 other 2.31641069392904e-07 0.000855317667143674 1 2.56133639612193 -5.48714725616097 1.18328289657358e-06 46.8315319167848 12.9581333869832 3.61406465871298 0.000329676932547372 -115.304900210813 44.83516410683 -2.57175149255779 0.0103853825430161 ARHGEF35 other 0.00784634888717942 1 1 3.61406465871298 -2.57175149255779 0.00193029181076325 36.3115157318807 12.675768725752 2.86464012696213 0.00434396087418728 -30.5397875842387 29.238379384568 -1.04451027133048 0.296735616341622 DNLZ essential 1 1 1 2.86464012696213 -1.04451027133048 0.465182738929312 11.3769218847823 9.46706256011983 1.20173726671119 0.229987267767682 3.81854190979079 19.5847153393058 0.194975614586908 0.845484700453019 TCL1B other 1 1 1 1.20173726671119 0.194975614586908 4.06466646890471e-84 517.764841949582 23.4080548589254 22.1190887098489 4.24005065125166e-77 -430.896557654658 104.827240959058 -4.11053991035548 4.57983797704885e-05 SUPT4H1 other 6.3299050920253e-80 0.529841455564781 6.59667080321733e-73 22.1190887098489 -4.11053991035548 5.07411390032288e-06 0.634281812548879 0.599215594365665 1.05852020293353 0.290287268240155 -8.50965060271159 1.9846776983929 -4.28767381706475 2.13563693070212e-05 TSGA13 other 0.0316371001685132 0.252645848902061 1 1.05852020293353 -4.28767381706475 1.67225228795915e-08 365.141283393498 66.0841527058179 5.52539857806713 5.11992313224158e-08 -23.7167905141833 153.365274686644 -0.154642506673309 0.877160938366722 NRAS og 0.000127643017139922 1 0.000531550419589321 5.52539857806713 -0.154642506673309 1.17746892711352e-06 1.88024279656212 3.75675307723198 0.500496774184452 0.61693348172994 -48.5727577210484 10.0817225742212 -4.81790263156498 1.89766758021147e-06 LTC4S other 0.00780897392461685 0.023789160785531 1 0.500496774184452 -4.81790263156498 0.280440141564936 98.314985747426 68.5445065925535 1.43432334164773 0.15208109567167 -110.212380525476 257.809742143986 -0.427495018647984 0.669195780961322 ANKRD39 other 1 1 1 1.43432334164773 -0.427495018647984 1.19691514049089e-12 137.845239214876 25.5343240366683 5.398429150383 1.00919505759843e-07 -314.813663098907 83.9492413817223 -3.75004774215207 0.000195933126267055 QTRT1 other 1.12773344537052e-08 1 0.00103018631479647 5.398429150383 -3.75004774215207 8.86586287019525e-16 139.930319172828 19.7916949730999 7.07015338317489 4.76265890424412e-12 -70.1298046155641 39.2541467768289 -1.78655786391874 0.0745647129008829 CHUK other 9.39072195211081e-12 1 5.70137897427064e-08 7.07015338317489 -1.78655786391874 1.5029055157092e-11 305.044890715828 50.0228062478926 6.0981163112711 2.0506911488689e-09 -218.008076568948 142.462987976158 -1.53027870372503 0.126535504413858 MXD3 other 1.34945886255529e-07 1 2.2524791579176e-05 6.0981163112711 -1.53027870372503 2.91193746879565e-05 139.185470036043 97.4363830958599 1.42847533553364 0.153732151332202 -766.113738217773 223.657852016113 -3.42538270537705 0.000660541312078896 GSTM2 other 0.169125328187651 1 1 1.42847533553364 -3.42538270537705 8.63151995457507e-82 175.926452924302 14.5041611411159 12.1293779910919 3.95260345691701e-30 -271.066471339051 31.8804827677345 -8.50258364385219 1.80201220786052e-16 COG8 essential 1.34323713533097e-77 2.73293171444127e-12 5.81348916443354e-26 12.1293779910919 -8.50258364385219 0.000267840325484235 43.0966246768051 22.7973898171767 1.89041925511726 0.059230224445656 -112.401048861866 44.0656470663104 -2.55076360714105 0.0110199357861021 ARHGAP19 other 1 1 1 1.89041925511726 -2.55076360714105 0.8113277834355 -0.675451778351917 4.69908902375153 -0.143741004892192 0.885759729059779 -6.25192835758065 10.51505325566 -0.594569347921786 0.552385580135818 LCAT other 1 1 1 -0.143741004892192 -0.594569347921786 0.703113141109931 -8.25966423388135 11.455216222037 -0.721039574791423 0.471222159164466 -28.6872733489246 48.5482973219661 -0.590901739739178 0.554853267575569 PTPRCAP other 1 1 1 -0.721039574791423 -0.590901739739178 0.140249525879754 2.23708100748031 1.31346483765273 1.70319063240259 0.0891014744039515 -1.67080266656161 3.68150787000889 -0.45383650546361 0.650126841079827 HNRNPA1P33 other 1 1 1 1.70319063240259 -0.45383650546361 0.032577329419036 0.43758833899052 3.36925562592449 0.129876859334605 0.896712305998886 -26.9457276768357 10.8895243920088 -2.47446322785314 0.0136503365569476 PVRIG other 1 1 1 0.129876859334605 -2.47446322785314 0.000335724462051661 22.3182399395089 6.17001372498322 3.6172107444655 0.00032579135496636 -13.4070585788647 19.6994773017246 -0.68057940693132 0.496429901507912 GPC2 other 1 1 1 3.6172107444655 -0.68057940693132 3.09082398000443e-100 272.414058080847 11.1123327754876 24.5145698553735 2.7883361542148e-89 -238.686448886418 52.4305590728132 -4.55242997800083 6.58357128270178e-06 KRT222 other 4.82693980957292e-96 0.0803590710766579 4.3486890661134e-85 24.5145698553735 -4.55242997800083 0.00109886211149771 61.6664310057858 29.5309949970738 2.08819347305758 0.0372616675408557 -172.70995640802 77.0648107833412 -2.24110011628491 0.0254367769485051 SIPA1 other 1 1 1 2.08819347305758 -2.24110011628491 0.0461635106972026 43.2877367031871 35.6145992355801 1.21544921555487 0.224748472793147 -267.441400598802 143.678971091402 -1.86138165221595 0.0632565142887319 ERV3-1 other 1 1 1 1.21544921555487 -1.86138165221595 8.68355548404673e-19 145.352362299383 46.0661596380081 3.15529584930836 0.00169235106778962 -588.747916758768 89.8885025689696 -6.54975775469208 1.3406569172049e-10 SYNJ2BP other 9.98869387329896e-15 1.91150863255074e-06 1 3.15529584930836 -6.54975775469208 1.71346257446677e-08 153.73747993889 36.0221112295562 4.26786422814519 2.34268086007404e-05 -200.858331056646 86.0513577504134 -2.33416806320736 0.0199639327973113 ARL2 essential 0.00013072005980607 1 0.204867441213475 4.26786422814519 -2.33416806320736 0.00498468793070315 4.40425015688325 1.62155757235511 2.71606153982348 0.00682250487289545 -2.02691197977316 3.36711276693839 -0.601973298808216 0.547449821474308 GBP7 other 1 1 1 2.71606153982348 -0.601973298808216 1.4100120442506e-06 97.6145683066744 23.4011100520307 4.17136486643734 3.53351556938611e-05 -63.393516400244 48.8975502288451 -1.29645587771895 0.195378443072568 RBMXL1 other 0.00928915934752296 1 0.304341695991226 4.17136486643734 -1.29645587771895 9.04856630640069e-30 142.091163586335 21.4447807036548 6.62590891228458 8.31416734321205e-11 -375.992549291992 50.9910970692603 -7.37369013224579 6.2225931458843e-13 SRA1 other 1.23576270046514e-25 9.16090162937087e-09 9.59953761447263e-07 6.62590891228458 -7.37369013224579 1.07948352752492e-23 53.7624805637881 20.3389924916007 2.64332073410175 0.00845090992264378 -294.691577001531 37.1782939594567 -7.92644163077776 1.32393937806045e-14 TMEM110 other 1.36770562937407e-19 1.98114288532966e-10 1 2.64332073410175 -7.92644163077776 0.00300825698563768 5.79553011841446 4.11402271726309 1.40872584249365 0.159489651707365 -19.7028837791474 8.64098974619621 -2.28016516138335 0.0229854079341429 KRT8P41 other 1 1 1 1.40872584249365 -2.28016516138335 7.28192814607732e-22 263.986376091576 25.9787872983391 10.1616127442736 2.6142599860594e-22 103.158850374552 68.7505615627905 1.50048011288368 0.134076690668951 DNAJC9 essential 8.95240246278745e-18 1 3.66859103843715e-18 10.1616127442736 1.50048011288368 1.33554501926827e-16 110.928376677687 13.018060117263 8.52111418125858 1.94416177190615e-16 -118.895352924469 88.625242316303 -1.34155179514356 0.180360241979126 C8orf82 other 1.44933345490992e-12 1 2.54957374767773e-12 8.52111418125858 -1.34155179514356 3.75229193056198e-16 779.449771398284 113.700478685989 6.85529014834597 1.93326257284642e-11 -612.349738544741 261.625329655877 -2.3405598355105 0.0196145740893605 VDAC1 other 4.01907988682494e-12 1 2.2733234594101e-07 6.85529014834597 -2.3405598355105 8.20491783962369e-12 50.684797697892 11.029319246679 4.59546020604613 5.39178517234213e-06 -147.169941965275 37.2894841885948 -3.94668752243798 8.98143822082789e-05 ZBTB9 other 7.47303916832925e-08 1 0.0495343303783072 4.59546020604613 -3.94668752243798 7.38123724989445e-24 261.049994327568 47.1421526503354 5.53750687338862 4.83124664484668e-08 -755.482207472172 122.326126849501 -6.17596769332565 1.30860172606187e-09 TMX2 essential 9.37269505991598e-20 1.82850919182624e-05 0.000502063151332467 5.53750687338862 -6.17596769332565 2.20272132435176e-20 535.615658014294 60.6397680695158 8.83274582119574 1.45059816874608e-17 -264.677862051836 133.857451551227 -1.9773113785193 0.0485174036449209 HEXA other 2.62762626781922e-16 1 1.93741891417727e-13 8.83274582119574 -1.9773113785193 1.4312582901561e-18 376.534025495894 48.6905363868591 7.73320758892924 5.18214944246285e-14 -345.390779087243 138.401297553987 -2.49557471780577 0.0128732045739875 NDUFS3 other 1.63735948393858e-14 1 6.49737897095993e-10 7.73320758892924 -2.49557471780577 4.89411428753681e-06 38.1629698089962 77.912217249699 0.489820096977714 0.624460875440236 -704.993880854875 156.36211569165 -4.50872564454896 8.01002328146708e-06 LEPROT other 0.0305833201828175 0.0972657127068547 1 0.489820096977714 -4.50872564454896 0.269392098924956 -72.2971167438812 57.4397876191635 -1.25865919322726 0.20869037608892 132.532599065118 179.924378279208 0.736601678619965 0.4616804028089 LBH other 1 1 1 -1.25865919322726 0.736601678619965 1.96660348717639e-08 8.15618396634882 4.78793791406748 1.70348574119666 0.0890735420019134 -37.4041338748778 8.65980859757489 -4.31927951448633 1.87484204837735e-05 ADAT3 essential 0.000149560195199765 0.222599996403843 1 1.70348574119666 -4.31927951448633 1.3426385113874e-13 1526.62774358971 194.057785733386 7.86687191044801 1.96039394227855e-14 522.15974980084 592.653633290532 0.881053823802116 0.378676349858512 PPP1CB essential 1.3145773664994e-09 1 2.478722100617e-10 7.86687191044801 0.881053823802116 0.45059298277229 19.8182792473689 17.4606018973113 1.13502841218897 0.256864181510315 -9.56960394346149 60.9320895492904 -0.157053598756371 0.875260984906686 GPSM3 other 1 1 1 1.13502841218897 -0.157053598756371 0.380033680604327 7.97874370521954 5.73067683501134 1.39228644973901 0.1644140964551 12.3895902513284 34.4021958963788 0.360139518089093 0.718884930854289 LAT other 1 1 1 1.39228644973901 0.360139518089093 1.0688584239271e-24 83.4484635430175 15.8737819054134 5.25699950019845 2.1340781767297e-07 -175.284283088517 28.7098815292773 -6.10536420743388 1.99601843443819e-09 NCKIPSD other 1.37572767743656e-20 2.77785885520763e-05 0.00214026700344221 5.25699950019845 -6.10536420743388 1.93219314725059e-21 389.966641606153 57.5063341624769 6.78128152812439 3.13349946436213e-11 -1003.22633319094 200.070174483381 -5.01437226104024 7.22770526041662e-07 ATF6B other 2.35399091129539e-17 0.00924206671649474 3.66306087383933e-07 6.78128152812439 -5.01437226104024 6.54203212757644e-05 5.4367297432938 21.5982133319408 0.25172127248385 0.801356155927363 -146.668419358887 38.9484433048732 -3.76570683995826 0.000185076590851612 TREX1 other 0.364456609827283 1 1 0.25172127248385 -3.76570683995826 0.05491081550972 -0.616189020497165 0.741734115397492 -0.830741107501779 0.40649396806136 -4.71814896787435 1.95306964145018 -2.41576074285353 0.0160395235670736 SEC14L1P1 other 1 1 1 -0.830741107501779 -2.41576074285353 0.000489648653313752 213.166618295396 102.524574878593 2.07917583221216 0.0380716810997739 -560.577744724074 226.54614888302 -2.4744527659728 0.0136495932256662 S1PR3 other 1 1 1 2.07917583221216 -2.4744527659728 4.75324846005588e-11 233.349942548566 65.4038336655975 3.56783279313042 0.000391727670502394 -993.017333874093 195.796958300624 -5.07166884763056 5.41726906639357e-07 SLC35F6 other 4.16669760008498e-07 0.00696227420412901 1 3.56783279313042 -5.07166884763056 3.61005871419649e-15 1040.6527552102 139.833997550801 7.44205825076367 3.90564321931264e-13 -700.355626002859 487.554703887623 -1.43646573485687 0.151445740430236 CLIC1 other 3.74796295707879e-11 1 4.79261479441854e-09 7.44205825076367 -1.43646573485687 3.01739612214286e-07 274.304881517339 82.9920771998634 3.30519358922361 0.00101175568091559 -935.730836487159 289.735953320069 -3.22959862510906 0.0013146074331321 DDAH2 other 0.00210433205558243 1 1 3.30519358922361 -3.22959862510906 2.46642799933355e-19 100.330740362048 13.5266078016995 7.41728760328532 4.7293130443909e-13 -240.418112124362 59.3104064972501 -4.05355697799017 5.79501915861663e-05 ZNF337-AS1 other 2.88004797482178e-15 0.665210249217603 5.7915167541611e-09 7.41728760328532 -4.05355697799017 3.4151659959839e-09 41.4522823158869 15.7618393234116 2.62991402623401 0.00888953676425511 -256.344706045092 52.0345393251787 -4.92643366059457 1.25466186390674e-06 CENPBD1P1 other 2.71778909960399e-05 0.0158601806216451 1 2.62991402623401 -4.92643366059457 0.239593349662533 -512.970344533783 317.075186001502 -1.61781926552699 0.10633599407142 -989.481470940725 971.787710952356 -1.01820743336117 0.309074779782985 UGT2B11 other 1 1 1 -1.61781926552699 -1.01820743336117 0.000220641203628956 8.5271374470493 3.75154559719121 2.27296649504502 0.0234166194673043 -33.6410759727215 13.2847157643831 -2.53231432040983 0.011610860916478 ATP6V1G2 other 1 1 1 2.27296649504502 -2.53231432040983 1.79355086931184e-37 206.872469961174 14.8824700981756 13.9004122700394 8.47146734985414e-38 -4.73258799649805 75.1481309529669 -0.0629767891294601 0.949808162127368 ZNF134 other 2.59634423841582e-33 1 1.27419340409156e-33 13.9004122700394 -0.0629767891294601 4.80835292789167e-31 120.454986137825 10.7920715001195 11.1614332926252 3.62342311635495e-26 -80.9341128255633 39.3144772737189 -2.05863382748488 0.0400093601903393 GTF2H4 essential 6.64370124046792e-27 1 5.2246137914722e-22 11.1614332926252 -2.05863382748488 4.82201517008528e-59 462.448155373036 27.0841593599958 17.0744880513474 1.27170264884e-52 -125.988040889569 86.2306124906464 -1.46105932975062 0.144578623609384 DDX47 other 7.39986448001287e-55 1 1.95397111994266e-48 17.0744880513474 -1.46105932975062 4.41991393243217e-12 49.4182185834481 7.11473038510557 6.94590179930126 1.07726800995988e-11 -38.1607660681952 29.8474416278008 -1.27852720323779 0.201608783688969 ZNF845 other 4.07206670594976e-08 1 1.27710122580743e-07 6.94590179930126 -1.27852720323779 1.4792668308866e-11 18.5675453699082 2.65708829888731 6.98792937279639 8.20510811665212e-12 -8.76245692388644 11.3332995171229 -0.773160270815018 0.439763966661293 ZNF321P other 1.32897332086852e-07 1 9.7575145723227e-08 6.98792937279639 -0.773160270815018 1.38457547629922e-23 1719.58676336985 193.930643440819 8.86701932639441 1.09451287715281e-17 -3373.1135615542 1019.39134789676 -3.30894858830588 0.000998902078295065 EMP2 other 1.75107260487562e-19 1 1.46489603478132e-13 8.86701932639441 -3.30894858830588 9.47507389469966e-32 68.9873504305645 14.5246578354872 4.74967129773014 2.61453317178409e-06 -232.033365950229 26.4763625740401 -8.76379318727626 2.44919777268717e-17 KCTD11 other 1.31769852653588e-27 3.73380200446159e-13 0.0245243211513348 4.74967129773014 -8.76379318727626 1.86245657378834e-33 14.0929917553661 1.10863695385318 12.7119989157718 1.79398022475547e-32 -22.0468251435951 10.1454722941455 -2.17307036128001 0.0302205851437956 C8orf44 other 2.62718124298584e-29 1 2.66047267331237e-28 12.7119989157718 -2.17307036128001 0.431996398871839 232.449373510335 181.136898897435 1.28328007670019 0.199942389271168 376.319588335348 701.695141700608 0.536300689532082 0.59197078942532 UBD other 1 1 1 1.28328007670019 0.536300689532082 0.0134055690448729 3.38917161343049 4.61377838933819 0.734576160238297 0.462912442436277 -33.8119806721888 13.8085046303984 -2.44863448846983 0.0146527718265538 PPM1N other 1 1 1 0.734576160238297 -2.44863448846983 0.00289037676245217 4.52139639639644 1.31906052256691 3.42773990961214 0.000654780130716303 3.47118993993996 2.95672302004211 1.17399902405824 0.240910060067448 SLC23A3 other 1 1 1 3.42773990961214 1.17399902405824 0.000260215776025049 24.8375282275801 10.9665965747924 2.26483467848824 0.0239242806161279 -75.7045751142148 29.9712872367544 -2.52590335931173 0.011829267289586 LTB4R other 1 1 1 2.26483467848824 -2.52590335931173 2.54604649986613e-08 9.58177540432802 3.80764831079462 2.51645494074751 0.0121467260942196 -45.8771865154708 10.440045546681 -4.39434735321205 1.34120322626062e-05 LTB4R2 other 0.00019227743166989 0.160743206667336 1 2.51645494074751 -4.39434735321205 2.07359638655889e-24 361.331333896347 35.2285810719566 10.2567666054533 1.1152454599097e-22 -77.5040647514879 163.511425601571 -0.473997853460971 0.635692321692644 DNASE1 other 2.65606961154328e-20 1 1.56993103391488e-18 10.2567666054533 -0.473997853460971 2.522743945308e-19 30.5935843533786 7.92049507220036 3.86258486047886 0.000125912545307788 -167.973490895874 22.6641489701693 -7.41141840873719 4.89948015560759e-13 MDP1 other 2.94454673296349e-15 7.2228136453967e-09 1 3.86258486047886 -7.41141840873719 1.2653614837753e-27 915.698606689314 82.642362666752 11.0802568699758 8.15325857986983e-26 -194.697370559677 236.593500916879 -0.822919352413146 0.410922564659134 IRF9 other 1.69115562306568e-23 1 1.17317237705747e-21 11.0802568699758 -0.822919352413146 1.48383118238484e-16 73.6324642938202 9.3525618125748 7.87297275007786 1.92648429650645e-14 -35.9087453449564 25.0933241453756 -1.43100791018849 0.153009615974921 GALT other 1.60743431987749e-12 1 2.43623204136206e-10 7.87297275007786 -1.43100791018849 2.96992436064005e-05 8.88893954981927 6.73815840585226 1.31919420922177 0.187661224928753 141.155060983637 30.6588922773014 4.60404960841139 5.16756477017023e-06 CLDN9 other 0.172404109135155 0.0634628629424605 1 1.31919420922177 4.60404960841139 0.933578419348765 -23.230313091783 62.6952586469539 -0.370527430512669 0.71113984681026 -23.4100237091451 150.359044866034 -0.15569415015906 0.876334297009279 ITGA1 other 1 1 1 -0.370527430512669 -0.15569415015906 9.61943926672775e-20 159.416285896197 16.7106656402101 9.53979268860487 4.90818385745163e-20 8.8890028278977 74.6664880926913 0.119049429736977 0.905280550800603 NUDT19 other 1.13374711197653e-15 1 6.7531701694677e-16 9.53979268860487 0.119049429736977 4.12329918248516e-06 25.9987755577801 5.16157845397446 5.03698157251893 6.49906059025555e-07 26.9323788728742 18.8299167920931 1.43029728544437 0.153222086776025 ZNF726 other 0.0259561683537441 1 0.00632553567249573 5.03698157251893 1.43029728544437 9.32524206748385e-07 324.97744345246 76.4959585695472 4.24829559011281 2.53107649470744e-05 -174.507554114475 141.360202456178 -1.23448856950083 0.217549996989978 TAX1BP3 other 0.00624604713680068 1 0.220811113398277 4.24829559011281 -1.23448856950083 1.55101452280314e-39 430.541119220742 45.4348382034756 9.47601303855435 8.2487002107288e-20 -1190.83065633078 150.316600451904 -7.92215000040397 1.34079207150623e-14 AP1G2 other 2.2666526236245e-35 2.00622717659477e-10 1.13163918190988e-15 9.47601303855435 -7.92215000040397 0.00255704367889701 151.80614714095 45.6067192981483 3.32859169607303 0.000932716004914524 17.8594533397492 155.271460021609 0.1150208372953 0.90847160060947 ZNF90 other 1 1 1 3.32859169607303 0.1150208372953 4.71262691313605e-43 275.75944426619 27.2406015108069 10.1231040789166 3.46007709768183e-22 -459.421922514999 63.7810783009086 -7.20310685792301 1.9673619298735e-12 NAXD other 6.9902395002547e-39 2.88238196345766e-08 4.85033607553039e-18 10.1231040789166 -7.20310685792301 0.936879532578486 0.28619240346023 0.796818567805882 0.359168843477491 0.719612369236428 0.367339290179646 2.56252553032572 0.143350489910223 0.886068072950022 TM6SF2 other 1 1 1 0.359168843477491 0.143350489910223 1.31128372893188e-06 11.6458804519947 4.23045756627101 2.75286544529982 0.00611019874933328 -47.4995722316294 13.7068435218944 -3.46539100382643 0.000572378607334515 MEF2B other 0.00866496288078188 1 1 2.75286544529982 -3.46539100382643 4.48618091084335e-16 1.06936277639747 15.5142881482716 0.0689276082909806 0.945073841512082 -193.390953101311 26.0515066307472 -7.42340763021596 4.71972532942588e-13 GANC other 4.79303568514504e-12 6.95876302570552e-09 1 0.0689276082909806 -7.42340763021596 4.73017149862675e-09 103.181209661074 21.9358047405459 4.70378045763484 3.24923491620696e-06 -231.061238765736 65.8924774071473 -3.50664063422622 0.000491639945345127 TTLL3 other 3.73305134671623e-05 1 0.0302677948073569 4.70378045763484 -3.50664063422622 7.29873835847712e-31 449.665119596495 65.1953323023519 6.89719806183538 1.47501833399882e-11 -1531.75561693816 201.136400048349 -7.61550677336354 1.16737532305835e-13 REPIN1 other 1.00642303225041e-26 1.7323849794186e-09 1.74155414695241e-07 6.89719806183538 -7.61550677336354 3.00607743601714e-08 26.7502507630748 9.22961848709403 2.89830514668404 0.0039086873100643 -90.7917717478935 22.099272814226 -4.10836014882119 4.62190304266038e-05 ZNF891 other 0.000225936780091048 0.534615524944526 1 2.89830514668404 -4.10836014882119 3.00290263400325e-25 180.822528789036 20.9416111146719 8.63460446280324 6.48604010761161e-17 -346.689051375139 76.483224343758 -4.53287703741315 7.15481413922774e-06 SMIM7 other 3.89296297472182e-21 0.0871527910299332 8.57973385434864e-13 8.63460446280324 -4.53287703741315 0.865304180550281 10.0578927977816 26.9713299630862 0.37291052430663 0.709359495195168 46.9840237763534 99.4505359975236 0.472436104090211 0.636803967136841 UCA1 other 1 1 1 0.37291052430663 0.472436104090211 4.0920249082958e-47 107.165717432363 24.4528700897763 4.38254147831789 1.40905034517197e-05 -473.923186087391 50.3170852276723 -9.41873290042551 1.30435734900152e-19 FBXO16 other 6.14335699482449e-43 2.00623203849924e-15 0.125433661727209 4.38254147831789 -9.41873290042551 4.99451921349631e-06 63.045117567516 45.9426610107442 1.37225655154742 0.170548095505899 -318.302929165032 94.3020266304593 -3.37535618839204 0.000789712110649916 TSPAN4 other 0.0311757889306439 1 1 1.37225655154742 -3.37535618839204 9.16317864664145e-24 648.840783567253 63.7304288541748 10.1810202007569 2.4050946394505e-22 -670.993779323844 343.732023254876 -1.95208398964418 0.051457411298252 CPNE1 other 1.16179942060767e-19 1 3.37555032646878e-18 10.1810202007569 -1.95208398964418 0.425173426957885 -7.65022975746693 7.40596102580875 -1.03298271902957 0.302075243503323 -21.6835853133217 20.7276588075059 -1.04611840221288 0.295975268580482 CYP4F30P other 1 1 1 -1.03298271902957 -1.04611840221288 3.03252476717131e-18 117.766139983965 13.8968621428596 8.47429720273041 2.33131988968491e-16 -92.3357983678999 39.0456489809325 -2.36481658719493 0.0183969755830155 ARL16 other 3.44343187312303e-14 1 3.05379592349826e-12 8.47429720273041 -2.36481658719493 0.000610374355166455 -16.8014804022034 5.91797347427295 -2.83905976855829 0.00469443788065337 -54.4304752058829 16.4571657929054 -3.30740273816454 0.00100408447360857 PLAC9P1 other 1 1 1 -2.83905976855829 -3.30740273816454 4.98022860886913e-15 25.2952360562001 7.76468968061527 3.25772659264804 0.00119313328051583 -147.995882216584 24.0212422267538 -6.16104199855879 1.40696038487929e-09 PAXIP1-AS2 other 5.14457615296181e-11 1.96467948144544e-05 1 3.25772659264804 -6.16104199855879 1.45882173347768e-16 105.97148667813 13.5643880865714 7.81247823357693 2.98580525978669e-14 -47.8658646886455 40.6060105606302 -1.17878767275538 0.23900672432431 LYRM4 essential 1.58107099474311e-12 1 3.76360752996112e-10 7.81247823357693 -1.17878767275538 1.47310266854559e-11 70.3238889275762 19.3138920066219 3.64110397342313 0.000297654451231843 -196.223173103539 41.6039659332759 -4.71645355681332 3.06088375651347e-06 MYCBP other 1.32373005795507e-07 0.0379978109533582 1 3.64110397342313 -4.71645355681332 0.155358376484131 48.602123622997 25.3948681712895 1.91385611042253 0.0561601019089236 67.1671397909891 75.0640815586654 0.89479733044486 0.37128899238106 TMEM213 other 1 1 1 1.91385611042253 0.89479733044486 0.133457701851349 -2.18612548412083 2.61544277750135 -0.835852920555706 0.403605974487804 -16.4247817519212 8.34557133828356 -1.96808356026819 0.0495677356020636 PRCD other 1 1 1 -0.835852920555706 -1.96808356026819 1.3052085470164e-25 286.960994363081 25.6284401550948 11.1969746354631 2.7010807831e-26 117.924979361044 111.787211710606 1.05490581218116 0.29194366919298 ALG3 other 1.70055621590766e-21 1 3.8976595700133e-22 11.1969746354631 1.05490581218116 8.72381012694747e-58 80.6878485773027 4.85194710207283 16.6299934603227 4.47969113958719e-50 -98.1893778836138 20.2607812323601 -4.84627797702034 1.66490566884438e-06 AMZ2P1 other 1.33674942575216e-53 0.0209228695403673 6.86512667141737e-46 16.6299934603227 -4.84627797702034 4.84796987559263e-08 1.46360577680756 0.415581340045888 3.52182746377868 0.000464780718929833 -6.29595411666523 1.55732654822988 -4.04279637037041 6.0487089630841e-05 GCC2-AS1 other 0.000359186088082658 0.693423995527961 1 3.52182746377868 -4.04279637037041 1.39037101526409e-07 17.4093934884684 5.47812532985105 3.17798378828653 0.00157054629444452 -73.9639268727545 19.7244741040198 -3.74985545787915 0.000196647207643216 ZNF788 other 0.000995922758233671 1 1 3.17798378828653 -3.74985545787915 0.00015876035306601 -66.2318326374638 50.7051966359527 -1.30621389978995 0.192035927944158 -428.058924839212 101.724823430261 -4.20800853129692 3.01692969167681e-05 SH3D21 other 0.840953590190656 0.352890266035436 1 -1.30621389978995 -4.20800853129692 2.12756076102481e-11 0.603570872674034 0.734563813013613 0.821672483698633 0.411621310745016 -11.4880064215201 1.76814925241786 -6.49719270350666 1.84247228241207e-10 TTC41P other 1.89799695491023e-07 2.62091682173117e-06 1 0.821672483698633 -6.49719270350666 0.0119544192761947 8.13381944731023 3.02558958703106 2.6883419622328 0.00740291560841549 -5.35406915256902 9.90939269195932 -0.540302450311956 0.58921164376319 C19orf38 other 1 1 1 2.6883419622328 -0.540302450311956 1.6665399823862e-43 22.8254923763921 1.48655587865338 15.3546144508667 6.0777584634368e-44 3.49476729385163 5.6628351920819 0.617140915338347 0.537419927989647 C17orf67 other 2.47581179783294e-39 1 9.24244729534834e-40 15.3546144508667 0.617140915338347 0.00688153303071701 -0.989254022292903 0.615594937878386 -1.60698855923395 0.10878413331915 -3.68128804076335 1.16322094793208 -3.16473671429988 0.00166146788066903 CTAGE11P other 1 1 1 -1.60698855923395 -3.16473671429988 5.34235355993745e-10 140.728613537603 64.7751169174644 2.17257212699311 0.03024512635603 -1005.10353661429 189.260831044527 -5.31067908276181 1.59650936133407e-07 FIS1 other 4.44216698508799e-06 0.00209398167832577 1 2.17257212699311 -5.31067908276181 4.39788943434183e-05 35.3465310001199 7.94224665890598 4.45044488268118 1.04177796667615e-05 -35.9372746263035 65.9601458174505 -0.544833159189225 0.586093618420481 ANKRD36BP1 other 0.250943571123545 1 0.0937722321773147 4.45044488268118 -0.544833159189225 2.9446159564029e-19 140.506414530979 44.2144532630629 3.17783901329747 0.00156964989520214 -593.350623609141 88.1472190867562 -6.73135953415789 4.34785882098968e-11 SNURF other 3.42959420442246e-15 6.25091662693686e-07 1 3.17783901329747 -6.73135953415789 5.18863948504936e-20 -20.9940539052717 22.4209617587004 -0.936358311976738 0.349501941748251 -597.210131395806 62.5737225515063 -9.54410425085745 4.52026135074676e-20 ANG other 6.14750006188649e-16 6.96255855855523e-16 1 -0.936358311976738 -9.54410425085745 2.31660503659294e-07 16.7046761167975 4.69026779966442 3.56156126479446 0.000402254937116144 -23.538717740933 9.28602074811542 -2.53485517418321 0.0115392029937151 SCART1 other 0.00163042662475411 1 1 3.56156126479446 -2.53485517418321 0.147971121105514 14.8078803333453 7.5788971421657 1.95383049216497 0.0512323966892393 13.9136851511482 13.9676993681435 0.996132919561655 0.319627627220752 COLCA2 other 1 1 1 1.95383049216497 0.996132919561655 8.24058632450793e-12 22.9748865528687 7.8461628708228 2.92816844757384 0.00355271340534736 -152.095986321464 26.1345433812104 -5.81973000648692 1.00847346818362e-08 APTR other 7.50470196572937e-08 0.0001378583231007 1 2.92816844757384 -5.81973000648692 1.26887501117567e-20 18.6496477631433 3.4688177003196 5.37637009907583 1.13460315312721e-07 -73.0934029327056 11.1920365835212 -6.53084024406479 1.51633888951468e-10 SPDYE3 other 1.52087358839516e-16 2.15987311422472e-06 0.00115434524799162 5.37637009907583 -6.53084024406479 2.23388410890708e-05 5.40617750379332 2.52691079645572 2.13944137299034 0.0328492809884956 -27.2428141415652 8.05350770957524 -3.38272652414237 0.000769933768686031 MBLAC1 other 0.131173674875024 1 1 2.13944137299034 -3.38272652414237 0.00514428299189037 58.5457768157708 103.768080797996 0.564198319613725 0.572854294301678 -971.578640643477 330.651259673383 -2.93837876681069 0.00344087606087132 AZGP1P1 other 1 1 1 0.564198319613725 -2.93837876681069 0.339057186540134 4.32109866151562 2.96543940518762 1.45715291095022 0.145674307021308 0.410686037613918 11.4454610032892 0.0358820005149547 0.97139013897324 FOXI3 other 1 1 1 1.45715291095022 0.0358820005149547 0.994190931901123 0.532393610954791 8.18409185443975 0.0650522526413209 0.948156427038466 2.04279967258961 19.191442760954 0.106443256926248 0.915270131681075 SOGA3 other 1 1 1 0.0650522526413209 0.106443256926248 2.34279072907703e-25 3.51925862201251 0.595871272416219 5.90607197380425 6.22743982820117e-09 -5.44174327933398 1.29666949281189 -4.19670803508556 3.16999099049604e-05 VAC14-AS1 other 3.04187948263361e-21 0.370191547870127 6.72189855056035e-05 5.90607197380425 -4.19670803508556 0.000641375579887015 153.001289843272 56.6773357203042 2.69951450432171 0.0071621339354079 -252.770009162609 152.649847419181 -1.65588117797782 0.0983279127655983 NEURL1B other 1 1 1 2.69951450432171 -1.65588117797782 1.32232578716493e-23 71.4410162729618 14.0560551233813 5.08257940409784 5.13723338574259e-07 -164.666484917367 28.1493037936745 -5.84975337664903 8.52963680442841e-09 HAUS3 essential 1.67300658592107e-19 0.000116873083494278 0.00503397499468917 5.08257940409784 -5.84975337664903 1.91261446125883e-27 73.6776685994968 6.30066943880598 11.6936254655282 2.67726885288105e-28 70.9365450369976 13.8517381322149 5.12112951890281 4.23989910388742e-07 VSTM5 other 2.55142769131929e-23 0.00546989383392516 3.90586752946817e-24 11.6936254655282 5.12112951890281 0.0884134727247683 32.0880206534717 15.5732319297208 2.0604599480878 0.0398384289357057 -29.0513870124681 54.1776949664478 -0.536224123792265 0.592026956691063 LINC02085 other 1 1 1 2.0604599480878 -0.536224123792265 2.51939571282977e-12 219.527503757591 86.0364735938461 2.55156324507113 0.0109969884991597 -856.349026473129 159.800265723681 -5.35887110446917 1.23963103431149e-07 BBIP1 other 2.34303801293168e-08 0.00163358577701568 1 2.55156324507113 -5.35887110446917 0.0134134120468118 39.5759455335672 26.4915734423232 1.49390694439992 0.135778657827422 -103.877226126626 54.9545689254466 -1.89023821235955 0.0592564130759782 AS3MT other 1 1 1 1.49390694439992 -1.89023821235955 0.000232731214223477 26.3509230407653 33.8933713438011 0.777465386180436 0.437219745866334 -304.532125624676 87.2203436335858 -3.49152632216196 0.000518991516942386 PLIN5 other 1 1 1 0.777465386180436 -3.49152632216196 2.47162434686708e-113 735.264008944405 25.9492486632134 28.3346935584591 8.62351926731115e-108 -64.6673565525918 111.809418577573 -0.57837128012365 0.563261965242809 PPME1 other 3.8658676409348e-109 1 1.34845970782944e-103 28.3346935584591 -0.57837128012365 7.91584746179456e-09 1633.32536185488 317.883166653174 5.13813102798524 4.00233462124938e-07 -1213.78138587918 942.767278289627 -1.28746660372137 0.198534546056765 STARD10 other 6.16248724900706e-05 1 0.00395150497155952 5.13813102798524 -1.28746660372137 0.000128496214089165 -58.5666862519869 33.4314378954082 -1.75184466893753 0.0803639807955423 -293.30367727957 68.7640062325565 -4.26536633551616 2.35361687407447e-05 MEG3 other 0.689510684802459 0.277373748609676 1 -1.75184466893753 -4.26536633551616 1.28147849373516e-12 22.9955207921753 5.11185926752939 4.4984651549864 8.40101048395556e-06 -46.958204644126 10.8708419053069 -4.31964746182191 1.86320382277051e-05 NUTM2D other 1.20651200185165e-08 0.221292718030453 0.0761887640789929 4.4984651549864 -4.31964746182191 0.709391974133257 1.97387480422885 5.14580689724327 0.383588977131321 0.701436068183864 -6.50411260254803 11.0419265577803 -0.5890378430352 0.556085446432435 CPEB1 other 1 1 1 0.383588977131321 -0.5890378430352 0.0213870550265572 8.03388235874849 3.17700128505419 2.52876270354152 0.0117286378551791 -8.41304760813892 11.0804832313809 -0.759267211768562 0.4480222012072 EML6 other 1 1 1 2.52876270354152 -0.759267211768562 0.0756226622302946 5.65703822534855 2.58364591707228 2.1895563118645 0.0290669692424032 17.8493557394147 15.3203628937384 1.16507395178674 0.244603549776976 SLC6A10P other 1 1 1 2.1895563118645 1.16507395178674 0.0448742228876891 3.95737380831902 1.60512687211447 2.46545857344341 0.014008155089445 0.854996112345913 6.54098353358489 0.130713692819422 0.896052743890325 ZNF727 other 1 1 1 2.46545857344341 0.130713692819422 3.72750905414203e-25 294.903655792332 43.2801947775494 6.81382459825033 2.59484838484499e-11 -706.316958302081 111.360785752069 -6.34260034654035 4.85194755259272e-10 ZSWIM8 other 4.8237694669652e-21 6.84318682817677e-06 3.0416812767153e-07 6.81382459825033 -6.34260034654035 0.00907963573243905 4.69389197873704 1.65399641923564 2.83790939578105 0.00471177289420408 9.02071145165612 5.23665138871671 1.72261064983108 0.0855315006393948 ARHGEF33 other 1 1 1 2.83790939578105 1.72261064983108 2.62783207058789e-13 180.013704431062 31.6666361753903 5.68464877147134 2.17690029130851e-08 -115.321060355011 58.2386015748244 -1.98014817039945 0.0482085460209933 IFRD2 other 2.54426701074319e-09 1 0.000229793594750526 5.68464877147134 -1.98014817039945 1.11029259943651e-55 774.836756925398 45.0841589067356 17.1864525304394 4.13438795621615e-53 -190.589672612207 216.859468840822 -0.878862581518643 0.379867410695048 TOMM6 other 1.69486165303983e-51 1 6.35744836027357e-49 17.1864525304394 -0.878862581518643 1.8846074946523e-28 523.009101223637 85.6116732355328 6.10908631332023 1.96994383301878e-09 -1507.30086797085 214.858477406927 -7.0153195078085 7.20800575292523e-12 HNRNPUL2 other 2.54007398129237e-24 1.04883691710815e-07 2.16536226125424e-05 6.10908631332023 -7.0153195078085 0.287822423457531 -1.43160019834311 25.0416955274386 -0.0571686608350652 0.954432929993 -91.6748274311433 62.4656486702631 -1.46760386520704 0.142819929666822 METTL12 other 1 1 1 -0.0571686608350652 -1.46760386520704 5.21889424459266e-09 12.0879911186626 4.87793004048853 2.47809850045574 0.013511931102906 -101.264507062215 19.4947188515773 -5.19445844965451 2.91069315968226e-07 SEPT7P2 other 4.10674788106997e-05 0.00377720651331967 1 2.47809850045574 -5.19445844965451 0.000530699296802515 33.0254797988595 10.1533763942811 3.25265985583489 0.00121432589844924 -56.0184789612874 39.9978304334117 -1.40053793804009 0.161923453162865 POLR2J4 other 1 1 1 3.25265985583489 -1.40053793804009 0.0169736970072853 6.98548975289005 7.92302053585311 0.881670029918443 0.378351945896674 59.0990885197394 20.8687458645639 2.83194250882572 0.00480122304962163 KRT16P3 other 1 1 1 0.881670029918443 2.83194250882572 0.422423670846443 1.50604640617948 1.16591901532669 1.29172471362214 0.197003041510161 -1.22873754798275 7.31320087203234 -0.168016381538456 0.866633066064749 LINC01347 other 1 1 1 1.29172471362214 -0.168016381538456 0.606096719590395 0.554925006899564 3.90051536643881 0.14226966304871 0.886919489609663 12.7698020840089 12.8957795074403 0.990231112174436 0.322499788791223 APOC1P1 other 1 1 1 0.14226966304871 0.990231112174436 4.09764940247535e-15 7.47148840055786 1.17918168075343 6.33616390290594 4.99640701612001e-10 -6.01385009601502 2.64265777652885 -2.27568251531768 0.0232588092433733 EVPLL other 4.24557454590471e-11 1 5.62695358155436e-06 6.33616390290594 -2.27568251531768 0.01876122660252 52.487955534658 18.879974322402 2.78008617164159 0.00563096956661735 32.3976758732453 49.1042004105086 0.659774023452218 0.509690399897943 SMTNL1 other 1 1 1 2.78008617164159 0.659774023452218 0.0185048949444407 17.8324720624154 11.1488021539807 1.5994966827937 0.110298433846553 75.5649068891798 28.0317305023326 2.69569182976027 0.00724453494849159 LINC01588 other 1 1 1 1.5994966827937 2.69569182976027 5.55745462565788e-08 13.6340616212656 2.40343656967014 5.67273619504626 2.28547532303533e-08 1.05373429442404 9.38856653888664 0.112235908438159 0.910677759449954 HLA-F-AS1 other 0.000410584747743604 1 0.000241071937073767 5.67273619504626 0.112235908438159 9.6835177402831e-54 93.0834365369186 11.1576642719394 8.34255577764747 6.12142024498885e-16 -201.31458161691 20.2136139028209 -9.95935623311849 1.46319536227472e-21 ZSWIM7 other 1.4741219056033e-49 2.26370954497522e-17 7.96029488658351e-12 8.34255577764747 -9.95935623311849 0.000881671671789961 48.8816151312888 22.2973491742681 2.19226127506223 0.0287812453183797 -103.8953248201 52.5817046883902 -1.9758835404026 0.0486700535168746 ARHGEF28 other 1 1 1 2.19226127506223 -1.9758835404026 7.28393178770932e-15 3.14956627954772 0.391520437322692 8.04444922744056 5.82225868857063e-15 -6.02707828996223 3.96427475478635 -1.52034827623522 0.129026621190139 LRRC69 other 7.48423991187133e-11 1 7.43968215225555e-11 8.04444922744056 -1.52034827623522 0.267607614833448 -0.220357094358126 3.60872486108716 -0.0610623150393741 0.951332342470592 -20.936291671519 13.1864711076914 -1.58770997187468 0.11294162886675 ISPD other 1 1 1 -0.0610623150393741 -1.58770997187468 0.247525033704787 -13.8090509574801 8.2869953060732 -1.66635197046147 0.0962179080230942 -17.2219470985167 29.8078743320752 -0.577765019627204 0.563661396718339 COL28A1 other 1 1 1 -1.66635197046147 -0.577765019627204 1.07368833863035e-34 1114.01902974217 96.4869670054759 11.5457979903021 9.95771472615233e-28 -1069.48219513053 334.466719793481 -3.19757432306237 0.00146660794032847 PHB2 essential 1.52818061237257e-30 1 1.44795129832981e-23 11.5457979903021 -3.19757432306237 3.93240575964952e-31 114.869389051352 10.8551399860935 10.5820274265013 6.56892857637664e-24 -176.318637483466 40.9399116148364 -4.30676644205478 1.96804934535767e-05 CD27-AS1 other 5.43969688732318e-27 0.233331930385605 9.34561468561104e-20 10.5820274265013 -4.30676644205478 4.58023252967372e-51 99.7186680783416 16.7626092697253 5.94887505123931 4.86121218837593e-09 -365.078977715422 30.5674686759298 -11.9433827375736 2.46570406926067e-29 NEURL4 other 6.94088437546756e-47 3.85636116432368e-25 5.26615116366765e-05 5.94887505123931 -11.9433827375736 3.66568424550139e-11 5.26605074267933 1.02886163089354 5.11832746460369 4.27755673380668e-07 -12.1792058217341 3.61669411048397 -3.36749679394487 0.000811990811649287 GRID2IP other 3.23386664138133e-07 1 0.00421595991683987 5.11832746460369 -3.36749679394487 2.22215911092612e-29 16.5054418769142 2.4077530994711 6.8551222633832 1.92866875732497e-11 -28.4293794805301 4.4269806143072 -6.42184413201437 2.926083954539e-10 ALOX12-AS1 other 3.02324747041498e-25 4.14655357197721e-06 2.26811445861417e-07 6.8551222633832 -6.42184413201437 4.12799185808589e-43 248.267911814157 16.7864590677856 14.7897725667827 1.70844723137255e-41 -354.160911914717 140.45168897949 -2.52158528308217 0.0119839118763069 UBXN2B other 6.12470151984204e-39 1 2.58898093442196e-37 14.7897725667827 -2.52158528308217 0.741509410456758 -387.515429381967 865.902218959538 -0.447527932019394 0.654674392259777 -1863.90324965311 2478.71316102464 -0.751964075134299 0.45240211670477 MUC5AC other 1 1 1 -0.447527932019394 -0.751964075134299 0.613982155269739 -14.8743163162787 60.422670384705 -0.246171117919408 0.805645440552531 -159.707460741153 161.844195003573 -0.986797584785957 0.32419385501495 MSMP other 1 1 1 -0.246171117919408 -0.986797584785957 0.272281775300593 3.60512959222747 5.61140909347824 0.642464224612934 0.520844982116112 -18.0411053860049 14.8057097833023 -1.21852350546216 0.223558162398437 FAM166B other 1 1 1 0.642464224612934 -1.21852350546216 5.71038581680006e-59 279.893597991307 31.0919908496851 9.00211245218932 3.72192933014357e-18 -544.642500765248 60.0636856986842 -9.06775024592237 2.20905006969071e-18 PEX26 other 8.76258703587969e-55 3.38316018173132e-14 5.01269442183736e-14 9.00211245218932 -9.06775024592237 5.512958113059e-05 16.8967858576182 5.43117139951444 3.11107579096635 0.00196239368923595 -69.4952400681711 24.9199765848692 -2.78873617041707 0.00547773325874582 C5orf49 other 0.309828245953916 1 1 3.11107579096635 -2.78873617041707 0.884717732135495 6.67739898461809 14.7962360530284 0.451290379572677 0.651961119826817 -9.63358009351975 67.9139082694703 -0.141849885229627 0.887251386813703 UBE2QL1 other 1 1 1 0.451290379572677 -0.141849885229627 6.31574919198162e-32 112.096186149338 9.81502064800735 11.4208813378396 3.0825357789441e-27 -98.1404536864518 38.5047477859829 -2.54878837882373 0.0110822900935281 FASTKD5 essential 8.79847019934959e-28 1 4.47060164020263e-23 11.4208813378396 -2.54878837882373 1.49469030933516e-26 127.373725049392 25.0513531880087 5.08450478077814 5.08189833759346e-07 -684.613789748425 79.6339237039756 -8.59701190027192 8.76254771137051e-17 DHRS4-AS1 other 1.97224386316775e-22 1.33138149926563e-12 0.00498280132001039 5.08450478077814 -8.59701190027192 5.8161548699648e-46 120.461708193053 11.4537807653012 10.5172004477323 1.15428265849154e-23 -321.315422306178 38.0443700018452 -8.44580741619834 2.79304545142688e-16 HOMEZ other 8.7085286867983e-42 4.23006733618601e-12 1.63885051852628e-19 10.5172004477323 -8.44580741619834 6.89364662023668e-19 2.36657835379478 0.508170473241214 4.65705600465187 4.04301881674041e-06 -11.2859798178781 1.69783516883901 -6.64727649951762 7.31690557284637e-11 RNF212B other 7.94423836516075e-15 1.04792721614306e-06 0.0374302682053827 4.65705600465187 -6.64727649951762 4.85685183423552e-36 215.961752619203 20.6124656114661 10.4772401657311 1.5627266885098e-23 -456.164562391333 79.2225927532205 -5.75801102360146 1.42021827387487e-08 VPS16 other 6.97881040061302e-32 0.000193320111439847 2.21641526231345e-19 10.4772401657311 -5.75801102360146 9.46628669908281e-12 1.6066112547144 0.799960278580718 2.00836378721808 0.0451252308867256 -7.72043453937985 1.77905425966336 -4.33962848375447 1.71787441396939e-05 FAM66B other 8.59160180808756e-08 0.204461412750637 1 2.00836378721808 -4.33962848375447 2.69049384715263e-16 282.273434987861 45.6015056801741 6.19000251806562 1.24104558294028e-09 -297.303506242418 102.340340778681 -2.90504706140622 0.00383202971264981 MYL5 other 2.89550947830566e-12 1 1.37631955148077e-05 6.19000251806562 -2.90504706140622 3.51266985531203e-10 75.4570537114858 20.4434961410513 3.69100535401893 0.000246129840224376 -145.914012055574 41.466794702139 -3.5188157923392 0.000470176973218024 ZNF407 other 2.94888634353445e-06 1 1 3.69100535401893 -3.5188157923392 3.19899621346888e-11 165.834652834299 24.6054529981885 6.73975207229502 4.10180135434184e-11 -72.9932796532911 80.3671214360859 -0.908248029156314 0.364154608090437 MCM3AP-AS1 other 2.82983205043457e-07 1 4.77531713672477e-07 6.73975207229502 -0.908248029156314 1.13185112931866e-43 347.704340323392 22.4753927313843 15.4704455881593 8.01511936891691e-45 286.269724503847 186.898708602833 1.53168380158357 0.126197129959028 NPEPL1 other 1.68249670373219e-39 1 1.22014162153022e-40 15.4704455881593 1.53168380158357 0.0621608559072566 10.5339382795695 4.45777450496125 2.36304870689304 0.0184847079219206 6.62502736379661 12.8939628053452 0.51380847485074 0.607599638582202 AATBC other 1 1 1 2.36304870689304 0.51380847485074 0.00030526089693442 -5.08165711919043 1.89367656853222 -2.68348735134278 0.00753857925426515 -21.5488348107803 5.82921648624225 -3.69669489229617 0.000243729442939614 ANKRD20A11P other 1 1 1 -2.68348735134278 -3.69669489229617 6.67486886410812e-12 78.3141583663555 19.0772708797084 4.10510281371821 4.66178335570603e-05 -93.4754241236568 30.8386681824776 -3.03111092770112 0.00255253034792601 RSC1A1 other 6.10483506311328e-08 1 0.397044088405483 4.10510281371821 -3.03111092770112 3.20213324140963e-34 38.1187646564031 7.27492523062573 5.23974658817551 2.30198367704579e-07 -125.485257667087 15.3868693880771 -8.1553469066503 2.4107907857715e-15 TMEM242 other 4.54446749620854e-30 3.63113308152904e-11 0.00230359506561972 5.23974658817551 -8.1553469066503 4.23962555872316e-30 325.969332598075 38.590954424542 8.4467807925158 2.77255745350784e-16 -454.613754333303 91.6688621315069 -4.95930399660814 9.48517794544212e-07 TMEM167B other 5.80319946478026e-26 0.0120623007932187 3.62650514918826e-12 8.4467807925158 -4.95930399660814 0.0688948696879399 18.8768615583547 13.4557529540812 1.40288407663053 0.161227157163578 -19.7494315696825 21.8392242833885 -0.904310121706311 0.36623498371269 TNFRSF25 other 1 1 1 1.40288407663053 -0.904310121706311 2.00588448799514e-12 31.4014155071602 10.1724672572695 3.0869025884276 0.0021271346979471 -104.409340017449 21.0372475564265 -4.96307037018036 9.33571216058135e-07 SLC35E2 other 1.87229258109467e-08 0.0118750258682595 1 3.0869025884276 -4.96307037018036 0.258938564628089 0.125054800840115 4.54280057819692 0.0275281291105564 0.978048618515979 46.1296997667048 28.0381570457176 1.64524721405505 0.100497545407133 LINC01139 other 1 1 1 0.0275281291105564 1.64524721405505 2.45830333931499e-08 226.335254704047 38.0962898076694 5.94113641634682 5.08687107227668e-09 382.710948932445 430.632537148061 0.888718143471031 0.374551749983156 TSTD1 other 0.000185798566385427 1 5.50653793573951e-05 5.94113641634682 0.888718143471031 1.61099842931192e-10 38.98804751479 8.26652562717234 4.71637653751837 3.05798286673106e-06 -59.92307742135 18.5589029309698 -3.2288049376752 0.00131833240462957 CYB5RL other 1.37740365706169e-06 1 0.0285493280438012 4.71637653751837 -3.2288049376752 2.76393389899738e-10 -24.8611533912231 18.0015864750726 -1.38105346579587 0.167831660695108 -185.242108250247 28.976805583853 -6.39277189178754 3.51720847214997e-10 C1orf167 other 2.33248381736389e-06 4.97614654639778e-06 1 -1.38105346579587 -6.39277189178754 0.0430494364878313 1.14054275990938 2.72969828011647 0.417827409064682 0.676239091235658 -10.2434809936673 5.05468744628866 -2.02653103728272 0.0432004354927172 TTC34 other 1 1 1 0.417827409064682 -2.02653103728272 0.0439830718555561 -9.36221054089533 5.36052538131613 -1.74650988008133 0.0812941518119899 -26.1298847769736 11.0778953239385 -2.35874089914074 0.0186943038187506 MMP23A other 1 1 1 -1.74650988008133 -2.35874089914074 0.0175681332787165 3.29180702252736 19.4681929409948 0.169086418678115 0.865792816680388 -93.1000071448613 37.7888284075784 -2.46369128306159 0.0140661677367873 ATAD3C other 1 1 1 0.169086418678115 -2.46369128306159 0.024484805714286 420.865365360396 157.075066166035 2.6793900243564 0.00759815925908841 105.560103105349 570.73564835491 0.184954459055809 0.853333435557863 IFI30 other 1 1 1 2.6793900243564 0.184954459055809 1.95751635158115e-21 131.464473114017 36.0231323307751 3.64944591455487 0.000288042631785279 -627.555413416485 84.8957935185046 -7.39206723216148 5.46355545120908e-13 FNIP1 other 2.384450667861e-17 8.04890989072122e-09 1 3.64944591455487 -7.39206723216148 2.04672486092763e-05 11.1076754261158 2.70651513860795 4.10405072843184 4.70745000431075e-05 -2.25301669827727 5.79859419887676 -0.388545330299833 0.697770332121804 SYCE3 other 0.120920004070512 1 0.400886442367104 4.10405072843184 -0.388545330299833 4.16074640107793e-37 76.5391241612263 12.1440877901919 6.30258323914975 6.10808103686956e-10 -168.35004968213 26.3731401221466 -6.38339040790823 3.74901676900141e-10 CKLF other 6.00770172851643e-33 5.30148461304489e-06 6.85571015578239e-06 6.30258323914975 -6.38339040790823 2.84703293292087e-14 90.1376745287902 11.9062101020012 7.57064370245237 1.60479988560998e-13 -48.1027569256285 59.6098948712832 -0.806959264556625 0.420043261739685 PAM16 essential 2.85870576794585e-10 1 1.98930993820213e-09 7.57064370245237 -0.806959264556625 0.107402798174799 -49.6957243051096 37.4760040602223 -1.32606785465309 0.185376803610027 -161.049188629421 78.1980319839406 -2.05950437042322 0.0399238750028061 TENM3 other 1 1 1 -1.32606785465309 -2.05950437042322 5.83841415195034e-05 -0.223341299610166 3.39352042482463 -0.0658140431324228 0.947550324130206 -24.6691393475767 6.33183887003575 -3.89604660730058 0.000110099057598531 LINC01644 other 0.327067960792258 1 1 -0.0658140431324228 -3.89604660730058 3.02655091814084e-19 44.1727022036643 10.7180406627319 4.12134116613857 4.35201506831584e-05 -94.5527457135853 17.8276828835344 -5.30370359015719 1.65120102527462e-07 LINC00339 other 3.52381323399138e-15 0.0021638989436224 0.371792647286222 4.12134116613857 -5.30370359015719 6.44710416204751e-15 222.051916320932 27.5486488853029 8.06035596320645 4.88835608300635e-15 -41.3957766794734 87.6046750945125 -0.472529310048961 0.636739234553882 CEBPZOS other 6.63858315566032e-11 1 6.25416277259833e-11 8.06035596320645 -0.472529310048961 6.10282912806283e-18 77.3720794504914 8.6299383177707 8.96554257997041 5.21332974302038e-18 -26.9621896426537 37.6897363146448 -0.715372201534274 0.474692329145268 ZNF579 other 6.87971927606522e-14 1 7.0098431724652e-14 8.96554257997041 -0.715372201534274 3.98894647011825e-24 318.428613634576 67.5896806574318 4.71120162926178 3.12681634808515e-06 -865.550633489903 123.542173360019 -7.00611467282161 7.22987651787296e-12 RNASEK other 5.08710343334181e-20 1.05194703335052e-07 0.0291669428949383 4.71120162926178 -7.00611467282161 4.03784184664317e-05 58.7597436698334 15.4324169898032 3.8075528744887 0.000156565649608692 -19.0105952679244 32.1462491700243 -0.591378333670461 0.554516268536826 FAM19A5 other 0.231287580975721 1 1 3.8075528744887 -0.591378333670461 0.478055920175991 34.2046839982607 82.7733303453703 0.413233149560881 0.679598938383092 -373.969087845462 372.421136371989 -1.00415645440684 0.315750467549304 RPL23P8 other 1 1 1 0.413233149560881 -1.00415645440684 8.4542451710351e-13 33.5864150384667 10.9463065178691 3.06828746149572 0.00226012421679511 -238.03919874524 39.6425193524014 -6.00464356538986 3.5079443224977e-09 UMAD1 other 8.00532475245314e-09 4.85394255904006e-05 1 3.06828746149572 -6.00464356538986 0.449512590509989 2.56728035454164 2.05921824886368 1.24672572028648 0.213044660670739 1.37272314557927 6.1858068664019 0.221914970064002 0.824464917206962 PPP1R3G other 1 1 1 1.24672572028648 0.221914970064002 4.2628660051871e-09 20.2589498799058 4.98545372525447 4.06361205947644 5.5481604070445e-05 -51.9252181280632 14.3595363735625 -3.61607901378091 0.000327077249920198 FAM228B other 3.37320586990455e-05 1 0.469707260060388 4.06361205947644 -3.61607901378091 4.34576768520309e-07 5.28924212781842 2.00757708494675 2.63463961980753 0.00866356200521285 -30.110088500376 7.42714543271842 -4.05405936549102 5.77134807820237e-05 ZGLP1 other 0.00299423393510493 0.662608472858415 1 2.63463961980753 -4.05405936549102 8.36101317836975e-50 95.933096592481 36.2273399462698 2.64808558218084 0.00832897336554345 -882.881886765796 64.5962815382186 -13.6676890022444 8.69546184577211e-37 VAMP2 other 1.26359992164702e-45 1.36283973508786e-32 1 2.64808558218084 -13.6676890022444 0.55056090515549 -22.1524762001422 21.282323922345 -1.04088614950944 0.298398540424644 29.0842484701745 134.714862957642 0.2158948747869 0.829151978457895 RPL21P28 other 1 1 1 -1.04088614950944 0.2158948747869 0.838677384794186 -6.93164143731039 13.6844181746865 -0.506535341789875 0.612686872976007 -17.8807142245083 56.4756478816809 -0.316609280197532 0.751661996879508 SNORA81 other 1 1 1 -0.506535341789875 -0.316609280197532 1.6297396023157e-09 208.923782852931 69.4941565822187 3.00635036279277 0.00277358412002608 -433.518146999275 120.934374231896 -3.58473882841606 0.000369645904231538 MIR1282 other 1.32025205183595e-05 1 1 3.00635036279277 -3.58473882841606 8.06447341737337e-14 41.9381806659738 7.55296218915479 5.55254741327746 4.43590980278151e-08 -74.9053024771614 20.1532740430198 -3.71678082267259 0.000222985733533847 PPP3CB-AS1 other 7.96286105231447e-10 1 0.000461778210469556 5.55254741327746 -3.71678082267259 0.166205594246254 -0.802250876537612 10.6398355409442 -0.0754006839156858 0.939923532946462 -31.90299219393 21.3421665793915 -1.49483381058118 0.135535528784851 EBF2 other 1 1 1 -0.0754006839156858 -1.49483381058118 1.34856498036611e-05 14.2082816743496 3.1517086125738 4.50812033119606 8.02610371940161e-06 -7.12279570667293 15.4302685639914 -0.461611907604443 0.644545546977609 C6orf226 other 0.0811161835690216 1 0.072844917357289 4.50812033119606 -0.461611907604443 1.91405265199423e-23 430.563160990706 41.7806773648451 10.3053178681346 7.09580849713681e-23 -154.083224753189 136.273543781384 -1.13069067170056 0.258681725893027 PPP3R1 other 2.41496023102112e-19 1 1.00107666277606e-18 10.3053178681346 -1.13069067170056 1.51146323927081e-22 146.374378106171 15.2864202690959 9.57545164462679 3.70022198645952e-20 -50.4679369477644 40.3243091157779 -1.25155118722214 0.211278359477001 FANCG other 1.8808648549486e-18 1 5.09772471280033e-16 9.57545164462679 -1.25155118722214 8.0374606811186e-21 180.647387516448 31.9978996604586 5.6456014123853 2.67172861842347e-08 -649.843513650353 101.947533714326 -6.3742936192191 3.96720554335944e-10 AP4M1 other 9.68112139040735e-17 5.60724831498424e-06 0.000281146002516702 5.6456014123853 -6.3742936192191 8.85961970843828e-07 -6.37098706954016 2.47291471578128 -2.57630682889415 0.0102507230887464 -39.1626609816959 7.61922310503814 -5.13998086705191 3.84684488624205e-07 C2orf16 other 0.00595189252012884 0.00496896953955886 1 -2.57630682889415 -5.13998086705191 0.393470694355033 33.9800086866213 34.8832979897027 0.974105392691137 0.330435568773401 141.180353212023 114.984916847326 1.22781628306501 0.220044992120952 PLXNA4 other 1 1 1 0.974105392691137 1.22781628306501 0.109894687937028 -5.17435786338918 35.3133717874387 -0.146526870742763 0.883571243536566 -621.126270084884 295.507188248778 -2.10189902237497 0.0361185985052162 CEBPD other 1 1 1 -0.146526870742763 -2.10189902237497 7.55116733057478e-14 14.920759452516 1.92839934936712 7.73738046396501 4.97632857839611e-14 -6.52885203748273 8.23700045653727 -0.792624945443717 0.428342532461677 ZNF816-ZNF321P other 7.462063556074e-10 1 6.24180893588224e-10 7.73738046396501 -0.792624945443717 9.32061730144493e-26 7.8312461978922 1.73865369107377 4.50420128982426 8.22317591170925e-06 -22.103429813255 3.14509323261096 -7.02790924735334 6.57005013128728e-12 ARIH2OS other 1.21699300104966e-21 9.56467898112803e-08 0.0746006518710263 4.50420128982426 -7.02790924735334 8.23806126350793e-09 27.1225309116087 5.67866333203056 4.77621745219932 2.29809132213909e-06 -28.0493289219388 13.3559258881774 -2.10014110266723 0.0361745915114623 ZBED8 other 6.40591643850377e-05 1 0.0216503183458723 4.77621745219932 -2.10014110266723 0.00570873061646857 7.2605350656099 2.36589600571225 3.06883102557338 0.00225648744656416 1.81776036466084 5.1682886137668 0.351714174750005 0.725189323122191 HMSD other 1 1 1 3.06883102557338 0.351714174750005 1.04464540616996e-11 267.190632909585 51.3536086700599 5.20295729607337 2.78320142928871e-07 -220.221042622591 106.667447786773 -2.06455715583268 0.0394383243025514 NPTXR other 9.45717486205666e-08 1 0.00277206862357156 5.20295729607337 -2.06455715583268 6.21912231227396e-21 13.2735393369948 5.1098166423446 2.59765472345879 0.00964238380928974 -139.210983921128 16.1972531970272 -8.59472789785604 9.02577104322943e-17 FAM200A other 7.50834636760835e-17 1.37101462146655e-12 1 2.59765472345879 -8.59472789785604 5.80588941489458e-61 318.125523337579 41.3352647215317 7.69622561947367 6.62062684020744e-14 -690.372716990631 82.7839161735477 -8.33945467792726 6.13119270461651e-16 PPP2R2A other 8.9329414537568e-57 9.26852401156877e-12 8.27710767562734e-10 7.69622561947367 -8.33945467792726 7.40344964455244e-10 8.24093815839964 1.27021906709505 6.48780857718221 1.95771182258708e-10 1.83890912815 4.20101919911991 0.437729284487737 0.661755957957227 C19orf73 other 6.10414423193349e-06 1 2.23374918957186e-06 6.48780857718221 0.437729284487737 7.56133300540903e-07 56.6888231458516 10.5509578944591 5.37286033295821 1.15247902681083e-07 25.2822478865365 44.5103755527289 0.568007966065936 0.570264783680631 ZNF880 other 0.00510919271175488 1 0.00117195592236394 5.37286033295821 0.568007966065936 6.55447628943017e-07 183.865103110864 34.3135346195281 5.35838423961795 1.24542645806832e-07 110.290363536771 62.1827863338352 1.77364782183714 0.0766849297771646 TRIM16 other 0.00444852305763626 1 0.00126448148287676 5.35838423961795 1.77364782183714 0.841874000314375 3.78626569313763 7.64702567505075 0.495129198466109 0.620709216344647 0.520732042812556 13.7858075037098 0.0377730533864212 0.969882511935771 HEPN1 other 1 1 1 0.495129198466109 0.0377730533864212 6.97493101906129e-15 15.8135743770699 2.11679422705916 7.47052981103389 3.31497324784217e-13 87.6779517957853 19.6701752935586 4.45740571638409 1.01298778277569e-05 XKR9 other 7.17162407379881e-11 0.122287885136681 4.07774859217065e-09 7.47052981103389 4.45740571638409 9.62725228091197e-08 87.6602207044961 18.0560118085325 4.85490492773557 1.57474126884177e-06 -115.700109978041 57.3662189396861 -2.01686832628252 0.0441982305340056 SLC12A8 other 0.000696724247569599 1 0.0149742147254164 4.85490492773557 -2.01686832628252 5.83255862126852e-09 480.395519959835 114.320226066234 4.2021918298299 3.08863026084729e-05 -505.056339417399 231.008196673049 -2.1863135018201 0.0292172658872526 APOL6 other 4.57797526183366e-05 1 0.267837392814729 4.2021918298299 -2.1863135018201 1.71713095425796e-06 112.819925036226 24.7809453728331 4.55268850073447 6.60524698358714e-06 -40.8733823570823 61.4975643983564 -0.664634164896695 0.506579705042295 FADS3 other 0.0112283193098928 1 0.0603257207011013 4.55268850073447 -0.664634164896695 1.32330541638827e-08 176.118180905127 93.3231347489686 1.88718672362293 0.0596814160796258 -770.750770343285 177.742487755017 -4.33633387311204 1.73459233065205e-05 CCNL2 other 0.000101484292382816 0.206399141424288 1 1.88718672362293 -4.33633387311204 1.54543491564645e-12 1675.32668681106 276.85356265879 6.05130983586377 2.68820251127919e-09 -2407.20394617162 911.548111576698 -2.64078649892423 0.00851083550209789 UBA52 essential 1.44977249436793e-08 1 2.93901180558154e-05 6.05130983586377 -2.64078649892423 1.1995986933229e-06 37.7570857650992 10.7514930666525 3.51179929438905 0.00048226467109161 -97.1727133948984 37.4115506363589 -2.59739871087995 0.00964900759542142 PPT2 other 0.00794854094195753 1 1 3.51179929438905 -2.59739871087995 2.30899940365588e-10 23.8795856686971 3.93777125925403 6.06423890483187 2.54281565535466e-09 -35.7466238110734 17.2982406958701 -2.06648898229331 0.0392740142100627 EXOC3-AS1 other 1.96034049370385e-06 1 2.78362029791674e-05 6.06423890483187 -2.06648898229331 2.45656904923692e-44 210.841265981664 13.9138425822549 15.1533456509391 3.9134479929204e-43 46.9952604849131 55.4263997147581 0.84788585812475 0.396896959669319 TIAF1 other 3.65905959883839e-40 1 5.94765825964042e-39 15.1533456509391 0.84788585812475 0.0424550677225996 -3.76177885100465 3.99258400453477 -0.942191534788507 0.346512803129458 -21.2095124067561 8.4253073186319 -2.51735771819895 0.0121100819147439 BTBD19 other 1 1 1 -0.942191534788507 -2.51735771819895 3.79530851412514e-25 16.9153105519794 2.79521558389371 6.05152269808704 2.68786844314794e-09 -59.1724329455705 8.29675929983265 -7.13199344553289 3.20078335973904e-12 FAM185A other 4.91112921727793e-21 4.67698464525069e-08 2.93891535573796e-05 6.05152269808704 -7.13199344553289 0.116545628530257 -14.632766227669 11.0465626384684 -1.32464429945946 0.185849460350629 -58.4842404579818 30.8459943226866 -1.89600762569576 0.0584926025624295 RAB6C other 1 1 1 -1.32464429945946 -1.89600762569576 2.24942345019919e-28 38.4840034597695 8.35027299070542 4.60871201487731 5.09716958424205e-06 -103.71341890749 18.0823843529885 -5.73560526548313 1.6453467461233e-08 URAHP other 3.03042327210834e-24 0.000223454541591005 0.0468990573446111 4.60871201487731 -5.73560526548313 0.755629859791271 -1.11553016853805 3.44611176788003 -0.323706903222207 0.7462848111201 4.73196388921091 8.56430837115775 0.552521427783576 0.580818936015285 LINC01124 other 1 1 1 -0.323706903222207 0.552521427783576 0.000924648914651465 29.0278041440582 7.71546510967425 3.76228830426061 0.000186819577828517 21.1068006495561 21.5938927814003 0.977443060555355 0.328788341543378 POTEJ other 1 1 1 3.76228830426061 0.977443060555355 0.00249277866077279 47.2558556076056 18.3995763850581 2.56831215125046 0.0104943797793841 -141.165568158403 73.1473960492895 -1.92987824287389 0.0541593111790964 CYTOR other 1 1 1 2.56831215125046 -1.92987824287389 7.4538671526074e-07 3.6257279179739 1.44051602262357 2.51696465782483 0.0121271911608167 -8.75325349798486 2.66523573026046 -3.28423238462643 0.00108924597724512 DCDC2B other 0.00503732342173208 1 1 2.51696465782483 -3.28423238462643 0.303037499198533 22.3237393605794 14.6032740411446 1.52868043821423 0.12694026015257 9.17069338774797 37.472184456044 0.244733354109779 0.806757621469859 C10orf55 other 1 1 1 1.52868043821423 0.244733354109779 3.97472902667205e-08 4.54654714481062 0.768463347909 5.91641378496689 5.82318020438483e-09 1.74613530644994 3.18254857640246 0.548659435836095 0.583464287889608 EHHADH-AS1 other 0.000296196807067601 1 6.29136389281737e-05 5.91641378496689 0.548659435836095 0.177595601859916 20.1652879080158 15.0500785626205 1.33987924542134 0.180842987445688 55.4588175124784 31.1947007414827 1.77782816293311 0.0759895909527754 LINC00473 other 1 1 1 1.33987924542134 1.77782816293311 8.69330037290014e-33 18.7556185111826 2.97449285470258 6.30548447327098 5.9560289648469e-10 -55.8508294418667 6.95169698693468 -8.03412886764702 5.90065047565083e-15 TH2LCRR other 1.22071323836264e-28 8.8568763639519e-11 6.68921613041956e-06 6.30548447327098 -8.03412886764702 4.3236847107854e-15 51.8755370944206 8.02286310418487 6.46596313819208 2.27132810400096e-10 -50.3492071315218 17.0613610174102 -2.95106627660848 0.00330560528498036 NUTM2A-AS1 other 4.47587841260504e-11 1 2.58726984326749e-06 6.46596313819208 -2.95106627660848 0.186515963190855 3.61242552549797 2.06168269615027 1.75217337383845 0.0803136851064834 5.62978452143738 4.20036293948449 1.3403090643706 0.180710617081381 LINC01615 other 1 1 1 1.75217337383845 1.3403090643706 2.38085738284863e-64 165.600247783434 18.3311136026468 9.0338345707226 2.96435860939965e-18 -347.164878948903 40.2049131358412 -8.63488692976228 6.6872955172704e-17 EXOSC6 essential 3.67437719895029e-60 1.01687015635614e-12 3.99565896960978e-14 9.0338345707226 -8.63488692976228 1.98629285434872e-21 196.529495319071 31.8863418468105 6.16343813483669 1.38719563231429e-09 -645.995843919241 112.606333101806 -5.73676298770164 1.60311137231079e-08 VPS52 other 2.41910606731131e-17 0.000217798711042144 1.53507068671899e-05 6.16343813483669 -5.73676298770164 0.132375560806618 25.2158999387286 23.0610944450391 1.0934389952231 0.274683274927792 157.579341376977 80.6102007523176 1.954831273292 0.0511128612454663 HLA-DQB1-AS1 other 1 1 1 1.0934389952231 1.954831273292 3.31973233267268e-12 67.2008143117713 17.8223001456401 3.7706027708332 0.000181429773732308 -333.073809091948 63.8596333287608 -5.21571753124896 2.64276820143003e-07 ZNF844 other 3.07540003298797e-08 0.00343480583139861 1 3.7706027708332 -5.21571753124896 0.000170596741750919 218.304981545491 59.8869535091202 3.64528446938355 0.000295173336235238 -10.0177386662489 111.708972868876 -0.0896771173252823 0.928579854502666 CKMT1A other 0.898703635543839 1 1 3.64528446938355 -0.0896771173252823 0.00203179008004939 129.23525162154 44.04132269962 2.9344089527687 0.00348315704812896 301.355876733905 103.854034298794 2.90172527979882 0.00386172866494337 TINCR other 1 1 1 2.9344089527687 2.90172527979882 0.0109079054650634 3.32763350682443 1.11854649293337 2.97496217443565 0.00306085570782693 0.0288388610900682 3.6179414503719 0.00797106904178999 0.993643007419054 C1GALT1C1L other 1 1 1 2.97496217443565 0.00797106904178999 1.78284513594199e-08 105.580879889148 20.5269296674499 5.14353006512077 3.87263727765768e-07 -150.582398531521 78.0150298500428 -1.93017164539915 0.0541485691360828 NSUN5P1 other 0.000135888456261499 1 0.00382616563032578 5.14353006512077 -1.93017164539915 0.777067963719304 -1.01360940794327 1.47416998571796 -0.687579734876788 0.492013781540539 -0.371542031202551 3.14206691250241 -0.118247650845426 0.905915569782786 TSSC2 other 1 1 1 -0.687579734876788 -0.118247650845426 0.357538445222411 3.08299282271331 5.01982289169624 0.61416366458131 0.539365835862783 -15.2018948527459 13.9359626231891 -1.09083923829204 0.275830119621692 MED15P9 other 1 1 1 0.61416366458131 -1.09083923829204 2.56114239848283e-06 10.2253899514787 2.15571798028125 4.74338018470514 2.68776093870281e-06 -23.0103101762255 13.4357705275574 -1.71261559796889 0.0873520688223781 LGALS8-AS1 other 0.0164681456222446 1 0.0251785769808586 4.74338018470514 -1.71261559796889 2.53632031884018e-17 12.4958912253724 3.46264874146207 3.60876662877915 0.000335940653940647 -39.236951151076 6.67079202474394 -5.88190292929754 7.0740297401787e-09 ENTPD3-AS1 other 2.81252560156188e-13 9.71335023623937e-05 1 3.60876662877915 -5.88190292929754 0.014043504679273 1.96529998558923 0.725995034322029 2.70704328911083 0.00700756224192647 -0.187086995087028 1.52218899040479 -0.122906548573365 0.902227691430757 CFL1P1 other 1 1 1 2.70704328911083 -0.122906548573365 0.128139392918843 -200.889331837028 188.756318366705 -1.06427871435144 0.287672037227214 847.316875583037 661.246903366758 1.28139258009209 0.200598738306228 HLA-DPB1 other 1 1 1 -1.06427871435144 1.28139258009209 2.67299761144604e-21 67.5773239192785 7.15316403620857 9.44719337865162 1.08158116087576e-19 -108.94573755347 43.5230577620518 -2.50317287330993 0.0126060412505991 OSER1-AS1 other 3.2474247981458e-17 1 1.48230698098023e-15 9.44719337865162 -2.50317287330993 0.108878351486603 -74.2686239613329 41.6381546211047 -1.78366751930185 0.0750360860943615 -149.354994280951 76.7605687050104 -1.94572547859722 0.0522033260577416 C1QTNF5 other 1 1 1 -1.78366751930185 -1.94572547859722 7.20577031024013e-26 69.3469792558152 11.3090021031008 6.13201577147119 1.70968821131153e-09 -88.4065072564565 24.4946594370265 -3.60921561223341 0.000336595111718452 AFG3L1P other 9.42947102798024e-22 1 1.88441834650757e-05 6.13201577147119 -3.60921561223341 1.27826263074856e-14 131.618091473224 28.4656021293462 4.62375926127113 4.75436056583071e-06 -225.906930037748 55.6497111218587 -4.05944479285919 5.67138662497451e-05 CPTP other 1.30024874799743e-10 0.651358753878322 0.04381143261413 4.62375926127113 -4.05944479285919 0.094392338481802 3.69830321586327 1.70110717835826 2.17405655734903 0.0301435058018408 2.06901847537328 7.33520938866888 0.28206672308079 0.778002664588099 EGFR-AS1 other 1 1 1 2.17405655734903 0.28206672308079 0.00150632609151667 -0.911049129334992 6.52904148704034 -0.139537959920052 0.889076991858221 -44.0796333090307 13.1306169242081 -3.35701159842413 0.000843280611463446 SLC44A3-AS1 other 1 1 1 -0.139537959920052 -3.35701159842413 0.00119738891316226 2.97372360581955 1.91032567739134 1.55665792540691 0.120137576767029 -15.8849518354797 5.59499028753894 -2.83913841117087 0.00469393259633927 DNAJC27-AS1 other 1 1 1 1.55665792540691 -2.83913841117087 0.024130871776729 36.1734187452671 18.2776736751457 1.97910409104504 0.0483136908118995 -56.078139694845 44.8899995168559 -1.24923458004913 0.212122522935078 HAGLR other 1 1 1 1.97910409104504 -1.24923458004913 0.0536415027578373 14.153988249588 7.49661691753017 1.88805009050018 0.0595621041808729 -34.8558853998033 31.4439142501581 -1.10850974603545 0.268141671976706 VSTM2A-OT1 other 1 1 1 1.88805009050018 -1.10850974603545 0.000259257159902361 5.43327618168758 7.90291457925817 0.687502835466252 0.492059998250728 313.108411678899 77.7515885795424 4.02703555514598 6.45435892489001e-05 LINC01133 other 1 0.73824957382892 1 0.687502835466252 4.02703555514598 8.14239061445949e-10 73.1753867121671 13.1667470981753 5.55759035747773 4.27843422170632e-08 131.623719839629 25.5427635726714 5.15307278576759 3.58424807879174e-07 MSL3P1 other 6.69630204133149e-06 0.004636583314725 0.000445598924190713 5.55759035747773 5.15307278576759 2.82222335055711e-27 38.0917271553189 3.32521829170006 11.4554064767411 2.36353357188765e-27 10.0970901493716 12.8500862341953 0.785760497272171 0.432351813059253 MDC1-AS1 other 3.75694372426163e-23 1 3.43137803966649e-23 11.4554064767411 0.785760497272171 0.554317457000317 -3.21498424573049 6.20220913634689 -0.518361147625557 0.604427231662167 -28.1804546300981 27.1959935186941 -1.03619875518529 0.300591971033492 PRR29 other 1 1 1 -0.518361147625557 -1.03619875518529 0.000416908360686146 -3893.83188187392 1397.686404447 -2.78591239743405 0.00554047527468333 -18855.2318098579 5346.6429383446 -3.52655526604059 0.000459758930521573 C4B other 1 1 1 -2.78591239743405 -3.52655526604059 0.658199937055905 0.795927906635219 2.38931386458088 0.333119862749734 0.739172624690634 -5.80409515661823 7.88306355735416 -0.736274053150764 0.461882469973589 ADM5 other 1 1 1 0.333119862749734 -0.736274053150764 8.49556833575106e-25 14.4898087309897 3.227689150379 4.48922063306135 8.79320698817143e-06 -39.8415569288266 5.83771237836605 -6.82485781185027 2.43567597723031e-11 PRKAR2A-AS1 other 1.0949088471116e-20 3.51662897592511e-07 0.0796312824848804 4.48922063306135 -6.82485781185027 1.47069508301509e-18 257.737276791504 39.1426102050246 6.58457050875006 1.08135351187955e-10 -138.732872635917 86.301713511625 -1.60753323417188 0.108520869230793 ATXN1L other 1.68203396644436e-14 1 1.24463789217336e-06 6.58457050875006 -1.60753323417188 8.06102889949688e-16 111.255501897996 13.1928544014671 8.43301218314243 3.12373060368423e-16 30.1792896456212 45.363386765343 0.665278582521484 0.50615795261151 SMIM13 other 8.55033335369634e-12 1 4.08177877983418e-12 8.43301218314243 0.665278582521484 0.0094186413427063 -4.33569666449875 7.38867232231537 -0.586803213806629 0.557577974277951 69.126700131603 26.0220001673387 2.65647143521145 0.00812683602035385 HLA-DPB2 other 1 1 1 -0.586803213806629 2.65647143521145 0.034707677976955 -21.9051325199804 29.8159834269442 -0.734677511934255 0.462856015476568 -190.618847286495 73.2996510744969 -2.60054235582599 0.00956357719631815 LINC01087 other 1 1 1 -0.734677511934255 -2.60054235582599 0.000169295110139447 -4.63544568136191 2.12316122284166 -2.18327540626321 0.0294461177128799 -21.2626284641656 5.23231679422498 -4.06371198464772 5.54864541642252e-05 LINC01117 other 0.892185230434885 0.638094222888589 1 -2.18327540626321 -4.06371198464772 0.154600915985978 42.8750182762147 90.5051755643852 0.473730016088566 0.635886063497574 -562.916093312101 332.43623820116 -1.69330544816079 0.0909805451577893 HNRNPA1P10 other 1 1 1 0.473730016088566 -1.69330544816079 1.30505317979287e-11 10.0647908718884 1.48355017161024 6.78426052889338 3.07974343708112e-11 -6.07102411293424 5.34805017991777 -1.13518458292169 0.256802527716321 ZMIZ1-AS1 other 1.17585291499338e-07 1 3.60083602663525e-07 6.78426052889338 -1.13518458292169 1.51467662150624e-15 111.078170731205 14.1879703694255 7.82903881520461 2.57790307258292e-14 -70.9221797731924 51.5583548692614 -1.37557103893312 0.169519560265224 SVIL-AS1 other 1.59131925855445e-11 1 3.25279809698513e-10 7.82903881520461 -1.37557103893312 3.19703365354052e-16 22.932387894569 2.73913584845565 8.37212506546489 4.90367453012748e-16 31.1790959637921 12.8634069923619 2.42385986716473 0.0156845794086692 LINC00885 other 3.4323353304411e-12 1 6.38458423822598e-12 8.37212506546489 2.42385986716473 1.32198027342464e-09 287.460475155136 44.2628956293011 6.49438928629069 1.88259411172981e-10 126.616285820463 127.98388225564 0.989314307309064 0.322949206422805 SH3BP5-AS1 other 1.07543095243095e-05 1 2.1495459567731e-06 6.49438928629069 0.989314307309064 0.267622783159985 0.763573197781466 0.529754034609914 1.44137306730231 0.150057874168794 3.1897424575057 3.72558674669137 0.856171839332006 0.392281786080257 RASAL2-AS1 other 1 1 1 1.44137306730231 0.856171839332006 7.58673208277414e-09 24.8901586102497 4.92084583259488 5.05810575193829 5.79511379843908e-07 -54.4526995831371 25.7745211385539 -2.11265611067691 0.0350843503451613 NPIPA3 other 5.91461633173072e-05 1 0.0056554515558967 5.05810575193829 -2.11265611067691 0.133104571147586 -35.7110787950178 17.8069660093913 -2.00545554903536 0.045411893098725 -24.5482572621331 56.8735014527408 -0.431629082702628 0.666182973352077 PCOLCE-AS1 other 1 1 1 -2.00545554903536 -0.431629082702628 0.00155714906086532 -1.61892142757054 1.66344593035475 -0.973233573768929 0.330871367974807 -12.4048408900557 3.44867207871586 -3.59699055373067 0.000351365262183681 LINC00853 other 1 1 1 -0.973233573768929 -3.59699055373067 3.67423845397786e-09 6.1483886040089 1.04640992735347 5.87569789170396 7.41588332691889e-09 -2.7429696827252 4.13990037242893 -0.662569007938678 0.507892485469616 LINC00240 other 2.91881502784001e-05 1 7.97949045976472e-05 5.87569789170396 -0.662569007938678 9.98086403155645e-16 3.76456018752097 0.438857860915163 8.57808535016468 1.00100220545317e-16 -1.13309356794329 2.05595780721873 -0.551126858715123 0.581772161648173 OPA1-AS1 other 1.05577579725804e-11 1 1.31962120744891e-12 8.57808535016468 -0.551126858715123 8.00283074004835e-18 109.685406735012 12.8348685986496 8.54589245631641 1.35387291845246e-16 -68.4601125476312 36.1188711071687 -1.89541119224082 0.0585797150038861 NDUFAF8 other 8.99678231796235e-14 1 1.78007211318129e-12 8.54589245631641 -1.89541119224082 0.00429009449089195 1.67869412473022 1.47056203311881 1.14153234404535 0.25415534888857 -11.5349244412811 4.5234947292881 -2.55000284770896 0.011047772411954 POT1-AS1 other 1 1 1 1.14153234404535 -2.55000284770896 0.228176779897281 5.36041439994221 3.262675296117 1.64295061979407 0.100973117535475 -0.104380482466596 11.7632913589992 -0.00887340789929023 0.992923402779436 PRRT4 other 1 1 1 1.64295061979407 -0.00887340789929023 0.453045146802264 -2.13484049163947 1.96063183149955 -1.08885332643339 0.276700698597469 1.21138225791469 4.41284160309888 0.274512970749732 0.783794651432006 TMEM233 other 1 1 1 -1.08885332643339 0.274512970749732 4.05759968060961e-05 84.752600687154 18.4095324267403 4.603734561126 7.3104744449261e-06 45.5983562629391 45.8413760802235 0.994698679706754 0.321067018977678 GOLGA2P7 other 0.232378733708513 1 0.0665399383977174 4.603734561126 0.994698679706754 0.000297305462877452 4.44566361636033 1.30139610443788 3.41607263246004 0.000683407322865581 -14.6229976183082 8.05083974001617 -1.8163319716359 0.0698768875156158 TAF1A-AS1 other 1 1 1 3.41607263246004 -1.8163319716359 4.61718737092697e-16 14.1973974699697 3.93310742524048 3.60971515267006 0.000335011699024208 -57.6933427350682 9.34949293997701 -6.17074563352845 1.33331004842007e-09 PPP1R26-AS1 other 4.93069439341291e-12 1.86276746864768e-05 1 3.60971515267006 -6.17074563352845 7.61941400828862e-10 27.9711563489695 14.4315038867557 1.93820107512423 0.0531224568722024 -173.386387389688 31.2187794679115 -5.55391307235138 4.39965385119786e-08 CT62 other 6.2753493772265e-06 0.000589289636829441 1 1.93820107512423 -5.55391307235138 0.00164196148648739 27.2049486630081 7.60840630743193 3.5756435137322 0.000380359906008137 28.6388826105168 22.3073962015869 1.2838290202816 0.199746329561367 LINC01671 other 1 1 1 3.5756435137322 1.2838290202816 0.020450361436832 12.5009836065572 4.46796292246777 2.79791569972399 0.00532630273519604 5.32383503741363 15.1193026177813 0.352121732860381 0.724883838137994 BOLA3-AS1 other 1 1 1 2.79791569972399 0.352121732860381 2.15469944210554e-05 -44.7200556611881 13.2452705627266 -3.37630367378334 0.000787349471218678 -148.758051173228 36.8334894656587 -4.03866300291534 6.15157351225153e-05 RAB6C-AS1 other 0.126847156156753 0.70460123009329 1 -3.37630367378334 -4.03866300291534 4.74932641862738e-45 86.0144490828809 5.75297516638633 14.9512985186255 1.5619678845142e-42 -45.3212083590809 21.4458475199695 -2.11328595509595 0.0350352516995104 NUTM2B-AS1 other 7.09264407357813e-41 1 2.3709110519041e-38 14.9512985186255 -2.11328595509595 3.66667521460713e-08 99.3723525622922 16.7203405713279 5.94320146401184 5.03764720896507e-09 71.9346366190467 33.2845599397601 2.1612013723251 0.031121921400672 GBP1P1 other 0.000274120639044029 1 5.45476439786738e-05 5.94320146401184 2.1612013723251 2.25857156654941e-11 4.02647498677667 2.38690249121435 1.68690384362043 0.0922004508534063 -38.7127158532361 6.09000766189678 -6.35675979448254 4.39395109266719e-10 MKRN2OS other 2.01193555148222e-07 6.20338015262754e-06 1 1.68690384362043 -6.35675979448254 3.65582463900098e-12 11.1646211579399 1.58446782396405 7.04629086755958 5.55261821201754e-12 38.1831771543131 20.1071737853158 1.89898279897487 0.0580926239320796 C2CD4D other 3.37761638397301e-08 1 6.63260245425495e-08 7.04629086755958 1.89898279897487 6.382699822354e-06 1.34317797565725 0.789007072191821 1.70236493815698 0.0892572108366581 -4.05330827901441 1.27278081364427 -3.18460824956092 0.00153233616237711 MTOR-AS1 other 0.0394259368026807 1 1 1.70236493815698 -3.18460824956092 0.0324690637153671 61.9080678689349 45.4779730714969 1.36127588121854 0.17403239702403 -88.9218695192381 98.9087649038699 -0.899029217538626 0.369064714345245 ZNF469 other 1 1 1 1.36127588121854 -0.899029217538626 4.51389940614378e-09 37.6946468445207 6.88288879435175 5.47657356827467 6.73946037637127e-08 -51.607775418995 26.399468617346 -1.95487932605907 0.0511285937007119 SBDSP1 other 3.56778609061605e-05 1 0.000695512310841515 5.47657356827467 -1.95487932605907 8.80034320531746e-09 364.167548449086 59.8951142788861 6.08008771388989 2.29963357779883e-09 -15.2730824586955 168.051396926733 -0.0908834007809776 0.927619577019918 MCRIP1 other 6.82906632732635e-05 1 2.52085832798308e-05 6.08008771388989 -0.0908834007809776 0.0590159222319102 2.84797616011236 6.77391701622649 0.420432691054557 0.674335413332026 -31.3377829801147 15.0836786014271 -2.07759551288436 0.0382151208150798 FAM225B other 1 1 1 0.420432691054557 -2.07759551288436 2.56682627259644e-35 860.460849598843 70.2091481774481 12.2556799496284 1.17048689054247e-30 -605.941452000759 203.300849492618 -2.98051608496973 0.00300654345658062 FGD5-AS1 other 3.67133161769469e-31 1 1.72506357928149e-26 12.2556799496284 -2.98051608496973 0.0102027871533309 3.51568614332076 1.15610380777281 3.04097791191744 0.00247129436633213 -0.538589493300924 5.4146036945683 -0.0994697901604902 0.920801782361518 LINC02036 other 1 1 1 3.04097791191744 -0.0994697901604902 0.292238361076316 0.670720897227906 1.71096551613096 0.392013100734269 0.695200939569039 -5.22012929782646 4.08137010678204 -1.27901394905405 0.201433475555971 DBH-AS1 other 1 1 1 0.392013100734269 -1.27901394905405 0.00231158004633636 6.97318211557137 2.04733666983792 3.40597724756397 0.000708250536148589 -4.64341374468191 11.5613179589684 -0.40163359931468 0.688112304119696 PROSER2-AS1 other 1 1 1 3.40597724756397 -0.40163359931468 0.902106556134808 -3.81345090893178 11.2440924907529 -0.339151506630523 0.734626961173982 -10.1053970029002 23.7337648599738 -0.425781457873234 0.670436120352669 MIAT other 1 1 1 -0.339151506630523 -0.425781457873234 8.87905388440344e-06 8.57799419595781 4.03049218951566 2.12827461079601 0.0337767650674991 -54.517393807819 15.5478364627246 -3.50642958835607 0.000492830502920208 TRAM2-AS1 other 0.0542421401798206 1 1 2.12827461079601 -3.50642958835607 1.1966217220982e-06 13.0061433464072 5.59879134990258 2.3230269773553 0.0205489813062491 -34.7989873427642 10.374032852035 -3.35443195901756 0.00085123028565944 FAM229A other 0.00793120877406688 1 1 2.3230269773553 -3.35443195901756 6.87857011011778e-20 118.882337646898 14.719565242376 8.07648430434945 4.28965973915021e-15 -121.26161621042 42.5405199653588 -2.85049680420371 0.0045300841444857 ERCC6 other 8.12840629912618e-16 1 5.49248033000793e-11 8.07648430434945 -2.85049680420371 7.85026996764016e-05 2.85577747143641 0.829150585011157 3.44422053492006 0.000616775483950623 -7.51374271609554 3.80808343493473 -1.97310349010888 0.0489886237014925 LINC01529 other 0.432706880616326 1 1 3.44422053492006 -1.97310349010888 0.000311573342300766 2.89579777517516 0.955135374710571 3.03181920788209 0.00255879458186281 -2.98871299120222 2.20918066697527 -1.35286037755085 0.176720330073887 LINC00115 other 1 1 1 3.03181920788209 -1.35286037755085 1.42011814408806e-28 244.567389789162 22.5670248099285 10.8373785135187 6.94443023545859e-25 -157.217791281873 77.0172622445256 -2.04133186119645 0.0417061276487767 NOL7 essential 1.91659144726125e-24 1 9.94234076810607e-21 10.8373785135187 -2.04133186119645 3.53580765475421e-06 19.3632628752374 5.80989966767901 3.33280503671294 0.000918765968674363 -52.5722724972193 20.1022629776501 -2.61524150567872 0.0091661551634713 CTAGE4 other 0.0224170205311417 1 1 3.33280503671294 -2.61524150567872 0.379528334834741 -0.782744490739392 1.97651262852723 -0.396023015204634 0.692242756548453 -9.04689482795401 6.4952672725624 -1.39284411992872 0.164233795223244 NTF4 other 1 1 1 -0.396023015204634 -1.39284411992872 0.013985261409734 -4.31046707112054 2.35824770683685 -1.82782625363059 0.0681408559568639 -21.6296175494424 8.03520736543239 -2.69185555092123 0.00733148390217723 ELFN1 other 1 1 1 -1.82782625363059 -2.69185555092123 0.0929147671402787 9.13014829981811 5.32921778282088 1.71322484309983 0.0872548743805487 -18.6901698219356 20.0103331327097 -0.934025920407286 0.350715053209632 ABHD11-AS1 other 1 1 1 1.71322484309983 -0.934025920407286 8.38388753640107e-23 24.2204215557032 4.35419307214905 5.56255112126871 4.18153585295688e-08 -49.0712917467133 8.14050216461694 -6.02804234362886 3.07021638184598e-09 PIGBOS1 other 1.04798594205013e-18 4.25255671049486e-05 0.000435674220519577 5.56255112126871 -6.02804234362886 7.16190111845732e-14 4.24270524565998 0.593425237772396 7.14951939284936 2.84294646520601e-12 -4.66044693819358 2.63257293946841 -1.77030116367247 0.0772411505319693 LINC01534 other 7.08598496660167e-10 1 3.42177036552196e-08 7.14951939284936 -1.77030116367247 5.0381029973287e-05 -1.3099767045281 4.02031077033452 -0.325839662494326 0.744670279548103 -26.2116347939948 6.57787460585878 -3.98481825279075 7.66813583087659e-05 UBXN10-AS1 other 0.284652819349072 0.871636999895742 1 -0.325839662494326 -3.98481825279075 6.66223575194009e-08 -3.17569245549949 0.789376886230654 -4.02303704465393 6.56968028104193e-05 -15.9564708728234 3.16314848637835 -5.0444899888632 6.23140386004362e-07 LAMP5-AS1 other 0.000488075391187131 0.0079855440466459 0.552181627621574 -4.02303704465393 -5.0444899888632 0.256204023008875 9.65630775790558 8.86685223943163 1.08903447324443 0.27662088339064 -14.0966209490006 18.0627180996564 -0.78042633845173 0.435479411432675 KCNIP2-AS1 other 1 1 1 1.08903447324443 -0.78042633845173 2.36104113329973e-05 1.13606973698648 2.12482571386818 0.534664904312692 0.593099245959878 -11.9104743727132 3.27496845192691 -3.63682110149958 0.00030217408334113 LINC01772 other 0.138333400000031 1 1 0.534664904312692 -3.63682110149958 0.000351761866638679 12.6223623250781 4.32099434465841 2.92117075799504 0.0036335767195574 -20.6845677005658 10.7735849216158 -1.91993360158743 0.0553947363818669 FTCDNL1 other 1 1 1 2.92117075799504 -1.91993360158743 5.61084488507686e-23 105.166471293427 22.2815922719194 4.7198813267023 3.01443772648819e-06 -534.632980127953 62.5401036093426 -8.54864237941694 1.2992542897444e-16 BAIAP2-AS1 other 7.02982755651279e-19 1.97213808640302e-12 0.0281638916785792 4.7198813267023 -8.54864237941694 2.36186398476264e-117 30.8158150673904 1.02064321940997 30.1925437619669 4.03672041918801e-118 -1.78154806458723 5.56878284469679 -0.319916957488083 0.749154793526783 AP4B1-AS1 other 3.69513620416115e-113 1 6.31585276786157e-114 30.1925437619669 -0.319916957488083 1.56382843870056e-05 7.02141321231523 3.20821539570219 2.18857288127265 0.0290728254269489 -21.1731516625907 6.98629754033859 -3.03066846785981 0.00256187521732613 TEX22 other 0.0934700257811322 1 1 2.18857288127265 -3.03066846785981 0.297088099652434 0.00916038736886236 1.61482220735172 0.00567269097932782 0.995475970598515 -5.2142147184054 3.53833173669957 -1.47363647798299 0.141163250610461 GAS1RR other 1 1 1 0.00567269097932782 -1.47363647798299 1.29713663705805e-07 23.6085527146306 5.76124060458405 4.09782446784916 4.82781504941818e-05 -43.6460639900476 16.5707416135694 -2.63392339388763 0.00868852850129387 ZNF32-AS1 other 0.000931473819071386 1 0.410412557351039 4.09782446784916 -2.63392339388763 1.88086397137525e-07 19.5036483790816 4.67726802662292 4.16988042337261 3.55891143826757e-05 -11.1149453972179 9.6004532863023 -1.15775214625298 0.247485681827924 TMEM191A other 0.00133466107408788 1 0.30645786394922 4.16988042337261 -1.15775214625298 0.186277964833938 26.4514721336177 15.3258403047794 1.72593943350491 0.0849250822812787 42.2831884042576 35.437494595731 1.19317657432112 0.233319387067412 NPY6R other 1 1 1 1.72593943350491 1.19317657432112 4.75016538247397e-07 16.0153761280387 2.92904336992181 5.46778388210284 6.9805933588834e-08 8.46383656709611 7.30059261697492 1.15933555139298 0.2468327629236 CFLAR-AS1 other 0.0032581384358389 1 0.000719629369367289 5.46778388210284 1.15933555139298 1.05181696275963e-24 2.32722393832222 0.48814609465447 4.76747425372628 2.43001863251686e-06 -6.51989113970228 0.997084658322829 -6.53895442606571 1.49220622436946e-10 PSPC1-AS2 other 1.3538987944642e-20 2.12594620785917e-06 0.0228616152947186 4.76747425372628 -6.53895442606571 0.00340205560358301 1.36787018979884 0.83125343610593 1.64555132091451 0.100439140789271 -5.88673826776949 2.5737441296436 -2.2872274675512 0.0225692002567331 ST7-AS2 other 1 1 1 1.64555132091451 -2.2872274675512 0.00214452701319497 0.708997720248798 2.15182863960185 0.329486143645705 0.74191579088162 -17.042073315298 5.2786310877456 -3.22850243406124 0.00131984245952367 LINC01876 other 1 1 1 0.329486143645705 -3.22850243406124 0.0108039087901914 7.70918600324821 3.6930411989682 2.0874898458761 0.037310315218899 -9.08394515478125 8.10360072767689 -1.1209763980296 0.262794332113663 SLC16A1-AS1 other 1 1 1 2.0874898458761 -1.1209763980296 4.96491044855805e-15 96.7976263025144 17.3737831070021 5.57147661544723 3.99360907299444e-08 -191.023547361589 41.6714120023333 -4.58404306892441 5.6740350951268e-06 TMEM185B other 5.12974547545018e-11 0.0695110915212379 0.00041661329849478 5.57147661544723 -4.58404306892441 0.0245977074486025 135.454886190191 206.751844334164 0.655156845765596 0.512645245859876 2273.52970192103 854.147106612809 2.66175426260812 0.00800458013200186 ADIPOQ-AS1 other 1 1 1 0.655156845765596 2.66175426260812 4.6534120120257e-12 14.0036831422673 2.00687900487763 6.97784126907103 9.03761878641958e-12 -16.2458441698923 12.034180967654 -1.34997505967034 0.177603509313169 PLCG1-AS1 other 4.28300041586845e-08 1 1.07394024039024e-07 6.97784126907103 -1.34997505967034 6.0410230545019e-12 0.143258014330945 3.22395762876031 0.0444354519590975 0.964573699033326 51.9087654850152 7.48504002051902 6.93500172914451 1.16275671056124e-11 KIF4B other 5.53599352714554e-08 1.68727626269541e-07 1 0.0444354519590975 6.93500172914451 0.00245835586776212 5.01665063180931 1.44564280889385 3.47018682688834 0.00056167554300321 2.89933817849621 6.3306280447372 0.457985867753911 0.64714682746136 LINC01535 other 1 1 1 3.47018682688834 0.457985867753911 0.0201078902068854 10.2034898495665 4.49219325860276 2.27138265479259 0.0235121990616085 -5.09826450562808 8.71589087571413 -0.584939001454669 0.558830372787826 ENTPD1-AS1 other 1 1 1 2.27138265479259 -0.584939001454669 3.98084828253887e-08 5.05731168530801 1.32677285131973 3.81173889733842 0.000154131405757495 -19.649396630968 5.24383855280472 -3.7471398924855 0.000198421716559196 LENG8-AS1 other 0.000296613005531971 1 1 3.81173889733842 -3.7471398924855 1.27586982784741e-08 6.28253504142828 1.51320113648408 4.15181755415921 3.82747290350542e-05 -18.4776940659175 5.42739574136344 -3.40452308002799 0.000711583307663045 FAM66C other 9.79868027786809e-05 1 0.32858854876594 4.15181755415921 -3.40452308002799 2.76260151112292e-14 49.3397149048223 14.9062219486975 3.31000806741199 0.000998418473380427 -160.239657192834 30.684601936874 -5.22215205928003 2.57294937728666e-07 HSBP1L1 other 2.77503321792297e-10 0.00334483419047266 1 3.31000806741199 -5.22215205928003 9.95004642481002e-09 21.9887727919403 11.6357247006553 1.88976392598065 0.0593170734365137 -182.094585704469 36.5651172111495 -4.98000825904489 8.53292378042423e-07 SRRM5 other 7.69337589566311e-05 0.0108726514810166 1 1.88976392598065 -4.98000825904489 0.228800344652318 -1.66597461147336 2.39472304249823 -0.695685714760309 0.486924955578756 8.43131284504679 7.13631731485005 1.18146551968786 0.237937893430928 FAM30A other 1 1 1 -0.695685714760309 1.18146551968786 1.11992739532239e-18 18.8989015494286 4.00859882041309 4.71459040829661 3.08252273129741e-06 -55.2732654089198 9.64606112492525 -5.73013841536776 1.66477052295714e-08 CACTIN-AS1 other 1.28478070791385e-14 0.000225975950786203 0.02877226717393 4.71459040829661 -5.73013841536776 8.43874603055832e-26 5.54658235732825 0.504371672900424 10.9970140183176 1.55526731352085e-25 -1.10001739693436 1.91759585651146 -0.573644020557874 0.566446225976061 ATE1-AS1 other 1.10311288111458e-21 1 2.23398596914136e-21 10.9970140183176 -0.573644020557874 0.00172263955684918 45.891619571054 13.6320958604961 3.36643903040921 0.000817785242473137 3.20921305943661 33.6645900272202 0.0953290403014481 0.924090201045502 ERVMER34-1 other 1 1 1 3.36643903040921 0.0953290403014481 0.00234086699720236 106.746557569994 48.6321916085132 2.19497731932994 0.0286065339086169 -206.048231160521 120.097658451048 -1.71567234380765 0.086817690564668 DANCR other 1 1 1 2.19497731932994 -1.71567234380765 0.0218940505721583 2.4418641918783 1.23507707094186 1.97709458731685 0.0485344650455286 10.7701231691916 4.33963195486134 2.48180566490822 0.013372108526346 LTA other 1 1 1 1.97709458731685 2.48180566490822 0.885310368741503 -0.147374576930016 1.72127502090066 -0.0856194246361057 0.931800574390558 -2.64759462727801 5.36406035127721 -0.493580320483829 0.621802542852504 SLC8A1-AS1 other 1 1 1 -0.0856194246361057 -0.493580320483829 1.28222828096076e-16 38.5542538846142 11.7301844355944 3.28675598378692 0.00108153212690797 348.955000468581 40.188619161201 8.68293083345023 4.93075912346894e-17 LINC00511 other 1.39237169029529e-12 7.50412231000738e-13 1 3.28675598378692 8.68293083345023 0.830324470328865 0.866960224313881 2.62385982459728 0.330414077835483 0.741214316394387 4.29783520983202 7.53096176444639 0.570688757194608 0.568446290924367 ITGB2-AS1 other 1 1 1 0.330414077835483 0.570688757194608 2.57629721481448e-07 -123.978331681837 65.2606505430819 -1.89974097178195 0.057995690026653 -755.329576649009 135.387832663555 -5.57900633896722 3.81798307784701e-08 C14orf132 other 0.00180649960702792 0.000512487868539404 1 -1.89974097178195 -5.57900633896722 4.53982186239894e-14 7.73077733971525 4.05603727889143 1.90599267416698 0.057174063533891 -79.8351336970036 11.2822049963448 -7.07619953039931 4.54968037305113e-12 ZNF717 other 4.52166257494934e-10 6.63570882409507e-08 1 1.90599267416698 -7.07619953039931 1.21225309891283e-06 4.76736894565898 1.93965889517406 2.45783882801269 0.0142912516912511 -21.9669545262268 6.0056121011078 -3.65773782195736 0.000279431617943921 ST7-AS1 other 0.00802875227409966 1 1 2.45783882801269 -3.65773782195736 0.000161519395456779 4.20067337671009 1.65475859420491 2.538541507759 0.0114176420674512 -7.95830589887465 3.47502516185047 -2.29014338838249 0.0224064570601549 KLLN other 0.854599121361819 1 1 2.538541507759 -2.29014338838249 2.33810732002774e-25 136.988538940824 14.4481687405461 9.48137728737835 8.17384013307773e-20 -116.749934148776 40.7435690766703 -2.86548127212613 0.00432783063647935 PARG other 3.03603235505603e-21 1 1.1215326046596e-15 9.48137728737835 -2.86548127212613 3.13994976169950e-11 4.73440462219011 1.65950542731957 2.8529009572672 0.00450375357098051 -16.2158997028439 3.44025865874331 -4.71356991185291 3.12529712750857e-06 RBM26-AS1 other 2.77885553910406e-07 0.0387880626495088 1 2.8529009572672 -4.71356991185291 1.67740108372717e-11 -19.3855146183061 23.2653807032387 -0.833234360768811 0.405079594097626 -276.873317620016 41.2538143311489 -6.71145982763009 4.86689883575313e-11 TP73-AS1 other 1.50244815069442e-07 6.99227355732652e-07 1 -0.833234360768811 -6.71145982763009 0.000128038041914117 0.497026443250777 2.13686574939922 0.232596008144412 0.816162287969882 -47.2164835594336 11.4123719982638 -4.13730673751407 4.06867273856728e-05 HPN-AS1 other 0.687436247036892 0.471843977491648 1 0.232596008144412 -4.13730673751407 0.00134829403492899 13.2048540856704 4.45484950473983 2.96415267712653 0.00316790909371521 -12.4754107391391 11.0245716076472 -1.13160049960449 0.258300094645857 LINC01806 other 1 1 1 2.96415267712653 -1.13160049960449 0.00466280321092421 2.07921552895415 1.26131867971377 1.64844583878357 0.0999141860848983 -7.34360504635068 3.27613516165133 -2.24154520006102 0.0254460135700997 FGF7P6 other 1 1 1 1.64844583878357 -2.24154520006102 0.850561675485096 -16.7323266552088 106.071640322473 -0.157745525612125 0.874715644878095 -194.46256995587 342.220686630912 -0.568237332086239 0.570107437329587 AKR1B15 other 1 1 1 -0.157745525612125 -0.568237332086239 6.15453739419161e-34 95.5805485134818 73.3850377827351 1.30245280783883 0.193335981408632 -1476.80600161918 133.356186543784 -11.074146913569 9.56222433527885e-26 SCAMP4 other 8.71174768147822e-30 1.49065515162662e-21 1 1.30245280783883 -11.074146913569 0.427248360767934 -2.03680393860189 13.8781339058125 -0.146763531208531 0.883372943105852 57.093027417298 48.4332155321551 1.17879902851781 0.238992595488065 LTB other 1 1 1 -0.146763531208531 1.17879902851781 0.0590508187459846 2.44066572989393 1.28085511119758 1.90549712341152 0.0572453032573517 -2.19164844611561 2.89038996969524 -0.758253546785833 0.448629392635085 SLC2A1-AS1 other 1 1 1 1.90549712341152 -0.758253546785833 4.80018062305678e-23 55.4349634258025 6.42693958180965 8.6254060303759 7.19235537501942e-17 -54.315687758099 17.0586878309226 -3.18404840374884 0.00153634463906329 DNAJC9-AS1 other 6.01990651937551e-19 1 9.51117074792568e-13 8.6254060303759 -3.18404840374884 0.000117182071364434 105.746593280579 137.795310945544 0.767417937192139 0.443167856415774 -1398.87708392151 366.180041288423 -3.82018932271536 0.000148810153470428 CERS6-AS1 other 0.631142636368841 1 1 0.767417937192139 -3.82018932271536 0.000331417808180962 7.88169813423087 1.95472235739224 4.03213177790922 6.32148482880542e-05 2.71784314095591 11.8750585280396 0.228869873317971 0.819056546656809 LINC01132 other 1 1 0.532332237433704 4.03213177790922 0.228869873317971 0.244871350318395 2.19060488843875 1.71036222974164 1.28078418147111 0.200819288319665 6.16054110173439 4.37938802412484 1.40671277991301 0.160087812013843 SLC9A7P1 other 1 1 1 1.28078418147111 1.40671277991301 0.00674731633995978 1.0473921097926 1.8485966004586 0.566587707416945 0.571230611635091 -22.8482432548377 7.75720251604606 -2.94542307069788 0.00336471864648858 DPY19L2P3 other 1 1 1 0.566587707416945 -2.94542307069788 3.09126441995248e-13 117.130613958707 21.4124402663001 5.4702132266098 6.90113926757855e-08 -247.340477393381 66.2464840490061 -3.73363931601879 0.000208885595528739 POLR2J2 other 2.98430667102212e-09 1 0.000711714492665376 5.4702132266098 -3.73363931601879 1.7350007932697e-05 19.6708540830022 4.42463718184076 4.44575527316313 1.06583623895112e-05 33.2700855988018 19.5678642859573 1.70024102337411 0.0896678706045078 MELTF-AS1 other 0.10324989720748 1 0.095829336244095 4.44575527316313 1.70024102337411 0.00254650848717272 9.08579873184542 3.73244725315847 2.43427384651098 0.0152423408555543 -28.1952778103528 17.6584945790094 -1.59669770739508 0.110913805773363 CASP16P other 1 1 1 2.43427384651098 -1.59669770739508 1.92058745437245e-08 14.038944972702 2.35376881690063 5.96445363363598 4.43617759431556e-09 16.9363624332312 7.19181047437664 2.35495116196025 0.0188813635746765 RNF144A-AS1 other 0.000146156705277743 1 4.81192183655408e-05 5.96445363363598 2.35495116196025 0.050151633700348 -8.89937124371831 5.57597766638476 -1.59601988676692 0.1110759515014 140.65107934656 76.8626541609484 1.82990141157551 0.0678219895674048 NACAP1 other 1 1 1 -1.59601988676692 1.82990141157551 0.182737902752171 -1.37048507533583 2.0871984794764 -0.656614638622982 0.511706902006571 -8.01232163553807 4.33909715475578 -1.84654119273553 0.0653576282018486 EFCAB14-AS1 other 1 1 1 -0.656614638622982 -1.84654119273553 3.87920721843473e-14 10.0075524989583 1.25084762018961 8.00061681169552 7.89690003968021e-15 0.615585277193625 7.09248529445415 0.086794015304476 0.930868149312719 RALY-AS1 other 3.87494009049445e-10 1 1.00693372405962e-10 8.00061681169552 0.086794015304476 0.838561450072274 -82.9194363986481 175.372679929609 -0.472818436896388 0.636533060742391 -200.132301898088 413.211864779126 -0.48433338671208 0.628344936802268 ORM2 other 1 1 1 -0.472818436896388 -0.48433338671208 2.10521177238439e-05 19.8880048890749 4.42423783508225 4.49523864458005 8.49966481069332e-06 43.5735746902389 34.660568491656 1.25715118321642 0.209239352001914 PCAT6 other 0.124108568536471 1 0.0770409618441242 4.49523864458005 1.25715118321642 5.09614310840983e-05 99.2490315250834 48.4051700799825 2.05038080356063 0.0408204751112463 -217.478398033786 86.8780063731616 -2.50326183936203 0.0126063060649436 C19orf24 other 0.287728239900819 1 1 2.05038080356063 -2.50326183936203 0.0245119297609402 -10.4560408578757 7.89752195427607 -1.32396477254669 0.186147516331109 -65.0334031721241 24.310574435638 -2.6751076303976 0.00772671954781384 CYP4F29P other 1 1 1 -1.32396477254669 -2.6751076303976 5.56535405826314e-06 23.128133897567 10.0047391455869 2.31171783302006 0.02116386151825 -62.8610630213137 22.6121796595669 -2.77996477861515 0.00562362612523168 GUSBP11 other 0.0345775447639889 1 1 2.31171783302006 -2.77996477861515 6.05456872581825e-17 1.91372650088891 1.01079140832578 1.89329517952541 0.0588579672748628 -14.8671717773457 2.31112808865347 -6.43286360904721 2.78146758560452e-10 TSTD3 other 6.64004552160488e-13 3.94384288962865e-06 1 1.89329517952541 -6.43286360904721 2.22436667357287e-09 310.052193964987 64.753933781983 4.78815997509723 2.17870013613417e-06 -600.348411056184 197.639927479007 -3.03758667954355 0.00250051503478434 OST4 other 1.78950298888937e-05 1 0.0205429635836091 4.78815997509723 -3.03758667954355 3.59346890740057e-10 20.1971816642043 5.30938280318779 3.80405452251019 0.000159464014390371 -49.6951138199666 12.3332117737731 -4.02937326720071 6.43814689447847e-05 CCDC183-AS1 other 3.01492041330908e-06 0.736459623259393 1 3.80405452251019 -4.02937326720071 2.69375898184485e-06 70.5923765037812 25.2800772837584 2.7924114199261 0.00541887448203272 -128.254403482584 49.0633795901415 -2.61405562670116 0.00919950497186679 FNDC10 other 0.0172912389044621 1 1 2.7924114199261 -2.61405562670116 0.0168344171881953 21.7496670856763 7.62467862650226 2.85253558229689 0.00450247302677959 20.845233902922 16.9341894933788 1.23095551228315 0.218872416771265 ZNF883 other 1 1 1 2.85253558229689 1.23095551228315 0.00612638300517551 47.7791485885249 15.4027873523423 3.10198066723677 0.00202354434405662 3.0650095496748 47.7163708001191 0.0642339201049873 0.948807916865396 HOTAIR other 1 1 1 3.10198066723677 0.0642339201049873 3.00921327722952e-09 16.7087914414128 6.50244445960564 2.56961694101516 0.0104586218476657 137.371086680563 22.1586929329952 6.19942191969329 1.15525739947055e-09 LINC02095 other 2.40105127390144e-05 1.61608957611936e-05 1 2.56961694101516 6.19942191969329 0.528723547126159 0.31070613141439 1.31370600713079 0.2365111598241 0.813125568836443 6.64512777794155 5.88506514571339 1.12915109916528 0.259334524710184 SNHG26 other 1 1 1 0.2365111598241 1.12915109916528 2.40785093231224e-06 13.0017777378217 10.592194133401 1.22748672976285 0.220174532467479 -106.14051547127 24.9735641406817 -4.25011483636684 2.51714938239647e-05 PROB1 other 0.0155354542152786 0.296092281851297 1 1.22748672976285 -4.25011483636684 1.57343084548878e-07 8.70949823538441 2.38645934309626 3.6495481310335 0.000288366676311072 -25.4118195147732 7.29446195340472 -3.48371403910225 0.00053486599619974 TTC3-AS1 other 0.00112342962367899 1 1 3.6495481310335 -3.48371403910225 0.213907296102717 53.5227825723557 31.3629701727716 1.70655975111766 0.0884767163637948 98.5236303506288 70.7047222058805 1.3934519120766 0.164054315069687 CES1P1 other 1 1 1 1.70655975111766 1.3934519120766 0.0128477453640215 83.7877597890593 35.2805296109381 2.37490085078208 0.0178994263939312 -54.6935491145881 79.3569208085839 -0.689209568079309 0.490985249796905 DHFR essential 1 1 1 2.37490085078208 -0.689209568079309 1.09362676399877e-05 16.9307302768178 3.88497193830953 4.35800580947951 1.57159837741962e-05 -8.71127523486871 13.493661036413 -0.645582782267993 0.518823807452013 SAPCD1 other 0.0662847181659652 1 0.139243616239378 4.35800580947951 -0.645582782267993 0.000346554155226716 0.726880845054283 2.12440401504947 0.342157536845625 0.732364486242081 -26.4102931527483 7.15062327414694 -3.69342533373763 0.000243598728902231 WEE2-AS1 other 1 1 1 0.342157536845625 -3.69342533373763 1.75595661235127e-06 23.6221499341145 12.9374422767059 1.82587480808681 0.0684714050330884 -114.277798040007 29.8497114636634 -3.82843895087963 0.000145497928808877 LINC01128 other 0.0114734205051032 1 1 1.82587480808681 -3.82843895087963 9.38833428742246e-11 3.87605077773751 0.566667578154784 6.8400786054479 2.24288729524843e-11 -1.59879333174271 4.19247050619363 -0.381348736832083 0.703101162694473 LAMA5-AS1 other 8.10401015690307e-07 1 2.63382255081023e-07 6.8400786054479 -0.381348736832083 5.39691252378638e-12 7.43567784323695 1.29823130355945 5.72754471629982 1.69658829279674e-08 -7.96155344883285 3.18280480815281 -2.50142686363901 0.0126654015986112 UBAC2-AS1 other 4.95598477059303e-08 1 0.000179940154334022 5.72754471629982 -2.50142686363901 1.87118660345497e-46 39.2732871439571 5.36090758591881 7.32586535293277 8.71345002297362e-13 -81.292202793357 9.86117986510623 -8.24365886287191 1.27993969961931e-15 MED4-AS1 other 2.80397312527728e-42 1.93142900672554e-11 1.05981692629428e-08 7.32586535293277 -8.24365886287191 5.86188485858403e-08 212.531470162173 146.608979877127 1.44964837993072 0.147737105099227 -2183.77136228199 429.784760675666 -5.08108142049727 5.17904066409097e-07 RPL41 essential 0.000432079532926229 0.00666076419808739 1 1.44964837993072 -5.08108142049727 0.815728526278212 -83.7176119971468 184.100823891538 -0.454737845423597 0.649478261430991 286.520114368704 792.213370208403 0.361670384701196 0.717738022818528 VIM-AS1 other 1 1 1 -0.454737845423597 0.361670384701196 0.00646450392050642 -0.593298502057056 0.880361364782459 -0.673926101020645 0.500646663113936 -5.42379449899813 1.78094172831169 -3.04546432529256 0.00243659676824649 LINC00242 other 1 1 1 -0.673926101020645 -3.04546432529256 0.774988894861359 -229.972121312645 403.621892082587 -0.569771178976558 0.569068981644904 -553.513576878266 951.011039804307 -0.582026447339838 0.560790875132306 ORM1 other 1 1 1 -0.569771178976558 -0.582026447339838 0.474563039314882 6.20702721439103 78.3752388000625 0.0791962781794558 0.936905521414614 322.982146326461 273.912804037281 1.17914219987504 0.238855115346262 HLA-DRB6 other 1 1 1 0.0791962781794558 1.17914219987504 0.0131550627530308 -15.4658257088312 27.7634538652057 -0.557056977994142 0.577716770156638 -171.439309597038 58.8364278759758 -2.91382933645161 0.00371654562541855 RALGAPA1P1 other 1 1 1 -0.557056977994142 -2.91382933645161 0.136415310506535 14.377073593623 17.4185716828636 0.825387629673864 0.409526443582214 -37.7871897900813 31.4150088109455 -1.20283874556533 0.229580896766222 SPINK8 other 1 1 1 0.825387629673864 -1.20283874556533 3.14756514404672e-06 12.8371211050067 2.53518105142674 5.06359145347124 5.68698506366033e-07 12.9595320205923 4.51363245582035 2.87119789824289 0.00425274863724603 PATL2 other 0.0200594326630097 1 0.00555163481914522 5.06359145347124 2.87119789824289 0.000128510391930372 49.353810895747 12.2655615437181 4.02377100468131 6.54504173652295e-05 67.0806977819363 23.7764700186999 2.82130601090819 0.00495889340187753 NKX1-2 other 0.689510684802459 1 0.550241658789484 4.02377100468131 2.82130601090819 4.67061410901463e-07 8.95530749227102 2.25046551939533 3.97931335321111 7.84449513822397e-05 -7.8328366497826 4.47623412717522 -1.74987197435215 0.0807021535218152 ACVR2B-AS1 other 0.00320637658583854 1 0.65462311928479 3.97931335321111 -1.74987197435215 2.6095405847753e-08 62.7223763732951 10.6310141663327 5.89994288333567 6.39662974070226e-09 63.9633510009887 45.7188028044526 1.39906006013699 0.162364866115682 MBNL1-AS1 other 0.00019696812333884 1 6.9006841642696e-05 5.89994288333567 1.39906006013699 2.88964562246588e-08 14.7197961851101 2.46317740819482 5.97593828854484 4.14395245243994e-09 20.8071309174796 9.74474005870287 2.13521661862053 0.0331902061783731 ZNF492 other 0.000217590315371681 1 4.49826038712356e-05 5.97593828854484 2.13521661862053 0.00379737137100721 -244.055788940304 120.662420761585 -2.02263295730268 0.0436145556223529 -1321.87383033076 413.950876524899 -3.19331086197435 0.00149038082802443 C2-AS1 other 1 1 1 -2.02263295730268 -3.19331086197435 4.4227089092955e-24 12.6351457417675 1.17131503122402 10.7871455628498 1.16201079326069e-24 8.00300246435145 12.1168002498378 0.660488107366348 0.509227606396191 UBE2Q1-AS1 other 5.63585796311525e-20 1 1.6603972224902e-20 10.7871455628498 0.660488107366348 1.35987887966683e-17 79.4490780370332 10.0499421689393 7.90542638967426 1.56388989867964e-14 -151.853832591837 60.2833759362077 -2.51900014280106 0.0120625378417749 ZNF688 other 1.51803279337208e-13 1 1.98160489061697e-10 7.90542638967426 -2.51900014280106 4.584308068338e-57 338.63306962089 19.1557789007917 17.6778543631496 1.18427161350145e-55 23.9531147712971 69.2609902269161 0.345838468275154 0.729597082161246 PET100 other 7.01674192939815e-53 1 1.82413356627629e-51 17.6778543631496 0.345838468275154 0.324111734225774 -1.16219864065505 5.53507295912774 -0.209969886438172 0.833770079986932 -15.5059152854005 10.6336620108083 -1.45819147436133 0.145366972726347 EMX2OS other 1 1 1 -0.209969886438172 -1.45819147436133 0.00433883517370831 29.9922345648917 9.12055404392185 3.28842243798547 0.00107273708930049 10.0508061427029 22.0061064050404 0.456728053464322 0.648049167819587 STEAP3-AS1 other 1 1 1 3.28842243798547 0.456728053464322 6.79359977231757e-16 42.1549117913622 5.17873635448941 8.13999958789529 2.68192805032977e-15 13.8380342847726 10.1021124658319 1.36981590054324 0.171306396746988 LINC01315 other 7.22159655797357e-12 1 3.44600935186872e-11 8.13999958789529 1.36981590054324 0.518510654037906 0.283431772379146 1.4241090066379 0.19902393079325 0.842318937997276 3.50893650517299 3.12495298826608 1.12287657393526 0.261988901422265 GK3P other 1 1 1 0.19902393079325 1.12287657393526 4.28434112135213e-15 4.96854334118834 0.699716890471873 7.10079091822075 4.14050591184906e-12 -8.15324957339132 2.80478015701784 -2.90691217027868 0.00380744250435747 TOB1-AS1 other 4.43600679704799e-11 1 4.96405253771583e-08 7.10079091822075 -2.90691217027868 4.21194837343622e-07 6.65468944683973 1.24881069838845 5.32882161838252 1.44920122988738e-07 -2.08764628319827 4.30601698233855 -0.484820726848246 0.627998317957509 ALMS1-IT1 other 0.00290582318283365 1 0.00146528736353913 5.32882161838252 -0.484820726848246 0.627014299786918 4.59464517482333 4.82007734970658 0.953230589775291 0.340908601378129 6.5315049097369 21.1503480784089 0.308813116716718 0.757585270251523 ANKRD36BP2 other 1 1 1 0.953230589775291 0.308813116716718 3.11615474688616e-16 13.2921247221199 1.54027152608307 8.62972826351076 7.3830632310084e-17 12.1804598586997 4.77290648197344 2.55200052728951 0.0109933033259703 PRRT3-AS1 other 3.34706181363043e-12 1 9.7604095913931e-13 8.62972826351076 2.55200052728951 4.97175552066158e-05 2.8952727740876 0.663822411137911 4.36151706466883 1.54442849434745e-05 -3.83647189969347 3.1098699381611 -1.23364384234089 0.217866430333228 LINC02028 other 0.281202492248619 1 0.136944474593789 4.36151706466883 -1.23364384234089 0.10521703378751 -6.61205407401628 15.1610353242712 -0.436121540026431 0.662922526602208 -133.161653194822 64.0731574403273 -2.07827518596751 0.0381548533970805 TPRG1-AS2 other 1 1 1 -0.436121540026431 -2.07827518596751 8.9491904069699e-14 27.355191751221 5.91087534558481 4.62794258918931 4.65502623073273e-06 -120.182691977856 23.0114772883174 -5.22272822696487 2.54249799870433e-07 HOXB-AS1 other 8.81495255086535e-10 0.00330702714691472 0.0429146868211251 4.62794258918931 -5.22272822696487 3.30462856385438e-05 -0.39335928234101 0.940109964040367 -0.418418373793685 0.675807300070517 -9.12318639568871 2.04944997491486 -4.45152919434772 1.03598495788321e-05 MIRLET7DHG other 0.190809253276952 0.12498122531903 1 -0.418418373793685 -4.45152919434772 1.65472474387753e-09 12.6459310000078 1.95303815492938 6.4750045809858 2.11229624394546e-10 11.9279185184607 7.20200749842045 1.65619357117813 0.0982561128955252 TPI1P2 other 1.34016157006641e-05 1 2.40759525884903e-06 6.4750045809858 1.65619357117813 0.0566791911456023 5.3822629292712 2.24106845198132 2.40165039337052 0.0166632763293221 3.12648902479043 4.80941640774424 0.650076591362745 0.515923358571567 GOLGA6L17P other 1 1 1 2.40165039337052 0.650076591362745 1.44620513190661e-07 36.3940961937986 6.95553570601284 5.23239297906803 2.387906661065e-07 -22.6079138208336 24.9183874852511 -0.907278363586524 0.364659121419068 LRRC37A6P other 0.00103504901290556 1 0.00238742907973279 5.23239297906803 -0.907278363586524 1.0045107467631e-05 21.4558713981202 9.09013353091806 2.36034721878868 0.0186218748698468 -107.711687441194 30.9707317007086 -3.47785413925914 0.000547308602759698 PSMG3-AS1 other 0.0611043887255992 1 1 2.36034721878868 -3.47785413925914 1.3929770761225e-09 0.948394110200845 0.637974375132519 1.4865708516958 0.137705392507614 -10.100876479204 1.86214497847945 -5.42432334535624 8.75349750013895e-08 PPP5D1 other 1.13207246976476e-05 0.00116115144339343 1 1.4865708516958 -5.42432334535624 4.77801313295452e-12 13.3076658391739 3.1633623334404 4.20681048721372 3.04219846703115e-05 -20.3801404490766 6.43635446599415 -3.16641051339746 0.00163229883406824 THAP7-AS1 other 4.39624988363145e-08 1 0.263971560984293 4.20681048721372 -3.16641051339746 6.84959570400223e-22 11.3025921383394 1.66453528076971 6.79023885460263 3.01120071264493e-11 -26.5930517684874 4.738210191574 -5.61246772373629 3.21949038612988e-08 ZNF32-AS2 other 8.42431775635234e-18 0.000432828287511301 3.52220147358077e-07 6.79023885460263 -5.61246772373629 4.58235510646124e-13 21.4660327804681 6.70826642504718 3.19993742352252 0.00145701984483285 -154.080035429847 24.7307170971173 -6.23031005630673 9.50702827459612e-10 GTF2IRD1P1 other 4.38439736586211e-09 1.33250508296739e-05 1 3.19993742352252 -6.23031005630673 0.0304132610909241 2.00510717771605 0.807112334359211 2.48429752880429 0.0132833010425908 5.39765603325364 3.64803550892362 1.47960622095103 0.139562575071836 KLHL7-AS1 other 1 1 1 2.48429752880429 1.47960622095103 0.038525895590514 13.2933546579061 7.70679007121093 1.72488864171402 0.0851207909186387 35.7369299879852 14.7574993892835 2.42161148344255 0.015780866861436 SETSIP other 1 1 1 1.72488864171402 2.42161148344255 0.0253909763000952 -1.09224296642747 0.943637314729358 -1.15748174577087 0.247581690669533 -5.44040108323357 2.00604684740067 -2.7120010134773 0.00689863829072462 FBXW4P1 other 1 1 1 -1.15748174577087 -2.7120010134773 0.47620504365526 6.80052894968525 8.23545294808838 0.825762589204494 0.409302771382281 -8.90459374493303 16.2218156065593 -0.548927072092502 0.583281973850738 FOXD3-AS1 other 1 1 1 0.825762589204494 -0.548927072092502 0.0433011934487827 18.1398538586949 24.6896840883724 0.734713890779908 0.462832688295504 -189.361390764598 89.1518548923204 -2.12403197884456 0.0341213118063534 STMND1 other 1 1 1 0.734713890779908 -2.12403197884456 0.00651889189436733 78.7961086902227 33.3220706331889 2.36468224191751 0.0184008979728151 -451.018560059456 226.044276151877 -1.99526644840332 0.046519571641969 MIR205 other 1 1 1 2.36468224191751 -1.99526644840332 0.408919611735748 -3.46483319450948 3.43178238141146 -1.009630800973 0.313128608619683 -10.6453904739403 9.81378124664547 -1.08473892034011 0.278525868016151 LINC00160 other 1 1 1 -1.009630800973 -1.08473892034011 1.41020682846762e-49 614.038979644664 84.621592168352 7.25629196887542 1.37040327546407e-12 -1374.68018524946 180.400369428685 -7.62016280566924 1.12418163979467e-13 HSBP1 other 2.12997639371749e-45 1.66862280794723e-09 1.66106581018999e-08 7.25629196887542 -7.62016280566924 4.47413622592911e-09 -1.68169142245033 0.853381200677989 -1.97062159456322 0.0492881516026403 -12.1066836656461 1.94489704057832 -6.22484553837678 9.82092097420418e-10 LINC00271 other 3.53680468659696e-05 1.37630386532497e-05 1 -1.97062159456322 -6.22484553837678 7.09155097553928e-09 34.9574605827761 5.68276502298876 6.15148795372693 1.5230138190319e-09 40.875119748528 58.9332483859048 0.693583348416005 0.4882502826811 MIR92B other 5.5427562424815e-05 1 1.68110265344741e-05 6.15148795372693 0.693583348416005 1.50641061286569e-05 -5.88744824847856 2.49418159369545 -2.36047297572891 0.0186016133440026 -22.6816847155672 4.76501364820496 -4.76004611741494 2.48101890507055e-06 KLF3-AS1 other 0.090218931604526 0.0309581538974704 1 -2.36047297572891 -4.76004611741494 2.54119667411591e-19 4.87595404125502 0.506530269702787 9.62618491510103 2.30195497437054e-20 1.51897118027522 1.5508103166424 0.979469354810509 0.327781907751611 LINC00852 other 2.96583063836068e-15 1 3.17715825562621e-16 9.62618491510103 0.979469354810509 0.0394686155129541 0.0492284712247442 5.84063852227474 0.00842861119327948 0.993278180525248 141.915707324114 55.7164180637485 2.54710751796247 0.0111423954486178 APCDD1L-AS1 other 1 1 1 0.00842861119327948 2.54710751796247 0.227454891856582 -30.9916403884817 282.344045222938 -0.10976551803673 0.912635595559729 1569.79745252158 989.101330239995 1.58709467324312 0.113069059741239 HLA-DPA1 other 1 1 1 -0.10976551803673 1.58709467324312 0.0940393813092753 31.9274756089617 21.8650186745539 1.46020801921923 0.144825410772223 -68.5476141296751 64.925733120376 -1.05578498440032 0.291547479489799 LINC00689 other 1 1 1 1.46020801921923 -1.05578498440032 0.0285651953022609 7.51715524700259 3.08117536359579 2.43970380128898 0.0155753325219727 -2.52864701358274 13.1087732620204 -0.192897303434861 0.847236121108361 WASIR2 other 1 1 1 2.43970380128898 -0.192897303434861 1.6989862780343e-05 1760.74628281045 746.943591381156 2.35726807636798 0.0187651822324567 -8267.66819832464 2634.49615502632 -3.13823505969097 0.00179230323475743 RPS18 essential 0.101191622719723 1 1 2.35726807636798 -3.13823505969097 0.0176522435437264 4.82711508710614 7.50053484632792 0.64356945017986 0.520125375216282 -40.2670907227017 16.7004015191145 -2.41114506598023 0.0162323039249469 FAM225A other 1 1 1 0.64356945017986 -2.41114506598023 0.0453501944442962 11.3889291750491 4.94614432131106 2.30258731553354 0.0216871494830377 -20.55771213485 20.722256571678 -0.992059530956057 0.321619481760553 LINC02015 other 1 1 1 2.30258731553354 -0.992059530956057 0.00352143151818476 36.3524201981075 10.8886460360939 3.33856202852089 0.000902607157645508 3.97236487635028 43.923535767385 0.090438185518296 0.927973904937392 FAHD2CP other 1 1 1 3.33856202852089 0.090438185518296 0.000331787894200173 10.0331579873342 3.48977950900462 2.87501200618717 0.00419799125178962 -20.4495282804494 11.5928521360989 -1.76397732330009 0.0782959956424648 LINC-PINT other 1 1 1 2.87501200618717 -1.76397732330009 0.00888924614040972 8.08868108144384 5.53004448899649 1.46267920584336 0.144518566339949 65.5299436075508 22.1956908297488 2.95237233705388 0.0033822662533075 EMBP1 other 1 1 1 1.46267920584336 2.95237233705388 0.0778424152546721 1.99020776894708 1.34466035550393 1.48008213434777 0.139432340556102 14.4622426163646 8.17592194749617 1.76888217735415 0.0774758987755899 LINC01354 other 1 1 1 1.48008213434777 1.76888217735415 6.09417177570626e-12 4.43757488213569 0.80447324102968 5.51612490734415 5.40792863241684e-08 -2.98107183989794 1.47534641995842 -2.02059109614537 0.0438207400437251 DBIL5P other 5.58226134654694e-08 1 0.000560639961322654 5.51612490734415 -2.02059109614537 0.00603178227654102 7.12691651415795 2.7295949818578 2.61097949019062 0.00927970300420215 -1.56843149045575 4.48596730670624 -0.349630611019176 0.726752497363438 PIK3CD-AS2 other 1 1 1 2.61097949019062 -0.349630611019176 0.000679967984696827 16.0121139155499 4.40011126305549 3.63902477875774 0.000299908874763184 -0.176255087986703 9.21229029025159 -0.0191326024727223 0.984742377177647 PCAT7 other 1 1 1 3.63902477875774 -0.0191326024727223 0.0276590535003142 12.2967752170842 10.2836031182576 1.19576524644873 0.232311061970694 85.0480499469724 32.9814997494946 2.57865926634448 0.0101810693860628 LINC01819 other 1 1 1 1.19576524644873 2.57865926634448 0.0245403423888865 -25.9931561186729 12.8734445424768 -2.01912984771921 0.0440068599797051 -114.384885737777 48.59150421653 -2.35400997730104 0.018958079815023 CYP21A2 other 1 1 1 -2.01912984771921 -2.35400997730104 3.96714161109863e-06 12.583732776012 2.53360680929178 4.9667267745975 9.13019477753401e-07 -14.5149067704585 18.604922640395 -0.780164854808036 0.435633157318422 IPO9-AS1 other 0.0250326635660324 1 0.00880607286293155 4.9667267745975 -0.780164854808036 1.6036717358255e-43 25.9856594790445 1.82767754920172 14.2178577891895 3.16153962176442e-39 -8.4126150075247 6.75556899492281 -1.24528592837217 0.213563775232967 PRH1 other 2.38273546508952e-39 1 4.77171175112904e-35 14.2178577891895 -1.24528592837217 3.67492243969366e-21 7.72593820142786 1.04919194366562 7.36370332242099 6.73779211854229e-13 -9.27132872692414 3.0038123155559 -3.086520645418 0.00212923027501011 TRAF3IP2-AS1 other 4.45510847364062e-17 1 8.21673748856232e-09 7.36370332242099 -3.086520645418 3.82386977290846e-14 17.7322398788264 2.56109516032785 6.92369426700901 1.24903779618405e-11 -9.53483702215723 5.8463134144898 -1.63091444918529 0.103489279943943 DARS-AS1 other 3.82081067709014e-10 1 1.47811132800421e-07 6.92369426700901 -1.63091444918529 0.0021112723269738 0.484968073017543 0.781054532754952 0.620914485070528 0.534918361491644 -9.75187344055193 2.98439491759791 -3.26762164854544 0.00115362355820299 NEBL-AS1 other 1 1 1 0.620914485070528 -3.26762164854544 2.97490737311534e-10 1109.58779615876 180.360685990227 6.15204910131512 1.48884648554563e-09 -436.141010831526 636.0212784328 -0.685733363994059 0.493175004221215 TAPBP other 2.50695444332429e-06 1 1.64457982793371e-05 6.15204910131512 -0.685733363994059 0.426332724158399 9.54221412191354 7.30804134773734 1.30571430399308 0.192199607566499 8.32089221444236 16.6881473329681 0.498610903200987 0.618254324653553 PPP1R2P3 other 1 1 1 1.30571430399308 0.498610903200987 0.00114257228627223 -5.08155333326621 3.66977814384348 -1.38470314391925 0.166715108805468 -29.5207371661409 7.97345889150671 -3.70237528879546 0.000235533012708347 LEF1-AS1 other 1 1 1 -1.38470314391925 -3.70237528879546 3.83237422572094e-05 16.9332282653383 4.46793141368547 3.78994812083979 0.000167546224334632 -18.7446363339932 15.6526620701448 -1.19753663945419 0.231619949704363 ZBED9 other 0.219978280556382 1 1 3.78994812083979 -1.19753663945419 9.39695031671237e-12 3.89110030605289 0.838009135974699 4.64326716620709 4.30260815960883e-06 -8.70911273579662 2.3175312996772 -3.75792669424128 0.000189807183403569 TMEM253 other 8.53149119254316e-08 1 0.039751796786626 4.64326716620709 -3.75792669424128 7.34425211371273e-12 77.0271767241065 36.6832066260356 2.09979398773272 0.0362282091731081 -342.422525076667 66.1226897741171 -5.17859340336006 3.20152590020043e-07 TMA7 other 6.70383332939698e-08 0.00414853726147972 1 2.09979398773272 -5.17859340336006 0.0800968046499502 4.4669176352541 11.1580488483272 0.400331428547542 0.689069582838853 -40.7825705638167 21.6363495857567 -1.88490994759412 0.0599747710633023 LINC00865 other 1 1 1 0.400331428547542 -1.88490994759412 8.59623721119089e-05 -1.68209240936455 1.7486879591255 -0.961916847763821 0.336524305495824 -14.5904467263883 3.37258645562044 -4.32618908911088 1.80940257220313e-05 GNG12-AS1 other 0.471073799173261 0.21502940168062 1 -0.961916847763821 -4.32618908911088 2.37517701821149e-07 8.22938099158355 3.08614987065994 2.66655260971619 0.00790018340130798 -17.2606806988229 5.68637279211615 -3.03544655439296 0.00252116987723955 SEMA3B-AS1 other 0.00167022447920632 1 1 2.66655260971619 -3.03544655439296 5.2243811634575e-91 275.340315768551 11.3245401903569 24.3135978273986 6.76243667583283e-89 -84.4649554403262 69.4310654431776 -1.2165297320614 0.224311715038049 SMIM26 other 8.14689998629563e-87 1 1.05460199959613e-84 24.3135978273986 -1.2165297320614 2.17573115199804e-06 25.5790276592228 8.25271761770064 3.09946721118389 0.0020455377553511 -55.8205725306881 19.1705932900757 -2.91178116848295 0.00375078937897517 C9orf172 other 0.0140987378649473 1 1 3.09946721118389 -2.91178116848295 4.87300252708155e-18 22.6949972393299 2.44950444965553 9.2651381966346 5.40775095531995e-19 8.71766510851156 17.56675328502 0.496259323909645 0.619924849846339 MHENCR other 5.50308175383319e-14 1 7.35508207433067e-15 9.2651381966346 0.496259323909645 0.423061925300936 -25.3346998394478 32.0910935556924 -0.789462029253718 0.430184704016803 83.3975132662611 112.690733690977 0.740056529358979 0.459583783551894 HLA-DQB2 other 1 1 1 -0.789462029253718 0.740056529358979 6.58701162392187e-06 32.4244660308228 6.62935192424214 4.89104612356652 1.33148823980879e-06 39.0695075096051 26.3129111258218 1.48480368906292 0.138189214285998 IDI2-AS1 other 0.0406550357428458 1 0.0127250331078526 4.89104612356652 1.48480368906292 5.96876792162277e-20 271.084266694978 28.8658358615928 9.39118021715306 1.65210448516118e-19 -70.389068778495 130.302872413821 -0.540195833557302 0.589284696476463 LINC00665 other 7.06224620486406e-16 1 2.26057456704604e-15 9.39118021715306 -0.540195833557302 0.00486043438946973 2.8322247004168 0.952505016100433 2.97344859349084 0.0030805606000348 5.268329193259 1.92866316428081 2.73159631543207 0.00651578953327601 BMS1P22 other 1 1 1 2.97344859349084 2.73159631543207 0.000517694182976334 7.31132920341073 1.87487047772725 3.89964495695385 0.000109062323065619 11.9712713988304 13.4727599289042 0.888553753054523 0.374656969847821 SLCO4A1-AS1 other 1 1 0.898346355091507 3.89964495695385 0.888553753054523 0.000135928691786535 21.7449287338063 5.12027958210405 4.24682449173425 2.54942277006344e-05 28.9805124244998 17.8692327273967 1.62181067685506 0.105422220530186 TNF other 0.726402928907243 1 0.222207688638729 4.24682449173425 1.62181067685506 1.07245835823045e-09 51.5517758199963 8.26351741448509 6.23847851153933 8.91936462693632e-10 77.8505184607531 19.4616157603889 4.00020838039593 7.20951577676715e-05 COL4A2-AS1 other 8.7641297034592e-06 0.821308037289314 9.94776736842208e-06 6.23847851153933 4.00020838039593 2.54025133714143e-05 2.24877883409085 0.625504730778756 3.59514280777879 0.000354856231008523 -7.90599540760732 2.66205191999934 -2.96988775771484 0.00311562073201397 LMLN-AS1 other 0.148477690655917 1 1 3.59514280777879 -2.96988775771484 5.23982640453897e-98 114.026057111816 4.44775749499097 25.6367522825223 1.38363054368069e-95 -38.8944161316175 27.3505257375416 -1.42207197422281 0.155579496028533 PET117 essential 8.17989300012579e-94 1 2.16109254617487e-91 25.6367522825223 -1.42207197422281 6.23955037542762e-38 41.7374942866209 4.72898274795101 8.82589269430197 1.84713065901872e-17 -186.892711327145 22.01401658686 -8.48971429587729 2.39532635815306e-16 LYRM9 other 9.05171572963285e-34 3.62963803050934e-12 2.46333344686737e-13 8.82589269430197 -8.48971429587729 0.293965324566796 1.6710664333277 1.53934083623051 1.08557272957154 0.278148006616281 -4.03779504652359 4.90279991238781 -0.823569209161764 0.41054461501105 SEC1P other 1 1 1 1.08557272957154 -0.823569209161764 0.00843163666021327 -0.655539169025697 0.922307267908305 -0.710760059944438 0.477538665938474 -5.39147798162508 1.76841172981461 -3.04876850267799 0.00240999137019041 DPYD-AS1 other 1 1 1 -0.710760059944438 -3.04876850267799 1.32362930759334e-22 42.9338456987554 4.12799603013072 10.4006509176308 3.51090841071895e-23 -6.67552085699484 27.2662531031843 -0.244827216696497 0.806684978596106 DLGAP4-AS1 other 1.64778612502295e-18 1 4.96582885612089e-19 10.4006509176308 -0.244827216696497 0.189693342436459 1.2163611240114 0.671502576810947 1.81140201991191 0.0706576985261116 1.09455098090073 1.91198169057233 0.572469384146192 0.567252395738173 RPL23AP87 other 1 1 1 1.81140201991191 0.572469384146192 1.46697838404967e-15 75.8002605493531 12.3073853062947 6.15892479701474 1.42299025566069e-09 -157.35058567571 43.4629082544379 -3.62034184998754 0.000321652494069698 HCG25 other 1.54208767731301e-11 1 1.57368492373515e-05 6.15892479701474 -3.62034184998754 1.08841783617912e-07 86.7454352283073 15.1005375988146 5.74452628991942 1.5437172062026e-08 56.6397043791071 59.4323078373795 0.953012030663294 0.34101194393178 SNHG15 other 0.00078572883593771 1 0.000164019953159027 5.74452628991942 0.953012030663294 0.377437069374699 16.5011984915679 12.3826779970499 1.33260337509376 0.183221949798065 25.8009869374078 38.8979780568954 0.66329892262444 0.507421132636225 CYP1B1-AS1 other 1 1 1 1.33260337509376 0.66329892262444 4.74726227799896e-23 9.81983174386658 3.10667093110659 3.160885707444 0.00166029926995627 -59.0888993078889 7.27827925673508 -8.11852598994605 3.16140559190738e-15 MIR3936HG other 5.95491016878118e-19 4.75665085358384e-11 1 3.160885707444 -8.11852598994605 0.000523061557945841 74.6562265504871 32.3672358740622 2.30653698205702 0.0214766940580464 -167.777282765058 75.0607632650579 -2.23521951372377 0.0258308538104548 SNHG7 other 1 1 1 2.30653698205702 -2.23521951372377 3.87311507608173e-06 109.236921934445 28.38829153465 3.84795688747641 0.000133262405237081 -51.3972625245824 50.2202045258383 -1.02343793717802 0.306556553224659 PHGR1 other 0.0244703410506844 1 1 3.84795688747641 -1.02343793717802 4.10367974408953e-08 3.96748235235076 0.73236703711139 5.41734151225504 9.19928590634597e-08 16.2459257287704 5.57784091947622 2.91258319541605 0.00373593828379846 LINC01271 other 0.000305313772960261 1 0.00094209886966889 5.41734151225504 2.91258319541605 0.691068909365396 0.888210317630771 1.03335284426112 0.859542142418805 0.390420089809149 0.886267234764405 2.12862317134138 0.4163570361803 0.677312978878334 LINC01399 other 1 1 1 0.859542142418805 0.4163570361803 0.00959616502473983 9.91786884955732 14.1956089032258 0.698657515656379 0.485076046457386 -151.746174336263 55.5252234462046 -2.73292325393849 0.00648956375875299 HOXB-AS3 other 1 1 1 0.698657515656379 -2.73292325393849 0.0132748999496682 0.675010524211738 0.812097005577139 0.831194450387147 0.40623459209672 -3.66864305810878 1.61416224292843 -2.27278458171162 0.0234349414762771 CTAGE7P other 1 1 1 0.831194450387147 -2.27278458171162 0.0306459084293667 247.804143386061 164.591505369338 1.50557067225308 0.132782268673174 -357.456699991803 297.869786652748 -1.20004349554431 0.23066679600896 GPX1 other 1 1 1 1.50557067225308 -1.20004349554431 5.19807624291436e-05 15.5804302102583 6.86136045371412 2.27074941119359 0.0235679289499075 -33.9369335352898 14.3661679657003 -2.36228155039782 0.0185281183491661 USP32P2 other 0.292911596288224 1 1 2.27074941119359 -2.36228155039782 1.02403851077163e-11 352.979262678581 80.906644110107 4.36279698115035 1.54811395110845e-05 -1495.54651859872 310.209766329428 -4.8210813485818 1.87549815405401e-06 GTF2IP4 other 9.27574083056944e-08 0.0235187468518372 0.137240301765764 4.36279698115035 -4.8210813485818 0.951073126250115 0.655020518835364 2.71467229373794 0.241288983700291 0.809423941921679 -2.29293945242999 13.8268652570507 -0.165832197667563 0.868351889093543 HOTAIRM1 other 1 1 1 0.241288983700291 -0.165832197667563 0.0480422455017893 12.7758338178045 6.68434284634765 1.91130738076747 0.0564981254826923 -37.3151865964993 29.2355694426434 -1.27636257161699 0.202380127869832 TMEM238 other 1 1 1 1.91130738076747 -1.27636257161699 5.56779798227115e-20 17.3909741848493 1.95094947534935 8.91410792774894 7.56256635518758e-18 -15.7647594810164 8.57225976468678 -1.8390436027101 0.0664576444871226 ZNF529-AS1 other 6.59060247161437e-16 1 1.01512328185683e-13 8.91410792774894 -1.8390436027101 1.92887076619652e-05 3.28766118936519 1.98128809651306 1.65935544414326 0.0976237281677033 -17.6422099466861 5.01575622700358 -3.51735793133343 0.000472498719441417 B4GALT1-AS1 other 0.114324170312468 1 1 1.65935544414326 -3.51735793133343 0.0605185053298654 8.99334970854018 10.3891815059739 0.865645643342443 0.38706401720277 -35.1814020894322 20.0941173007585 -1.75083093040888 0.0805355864734207 TWIST2 other 1 1 1 0.865645643342443 -1.75083093040888 0.00424821188742813 0.864089633384281 7.87299465640243 0.109753616139139 0.912645401702346 -51.1730105542263 16.5092642804426 -3.09965421141433 0.00203807658984674 LINC01137 other 1 1 1 0.109753616139139 -3.09965421141433 0.0599316993206467 3.70121397776264 1.59649627115367 2.31833549795143 0.0208114665256014 -1.11103056766782 6.36275593995184 -0.174614676117253 0.861449223053614 ANAPC1P1 other 1 1 1 2.31833549795143 -0.174614676117253 0.011260364236697 -6.61525288624263 2.33232470784934 -2.83633443661566 0.00473345436510349 4.94321740763816 8.28428544137256 0.59669810300732 0.550957192759719 LINC01122 other 1 1 1 -2.83633443661566 0.59669810300732 0.00426327425072223 9.83543556709728 7.2811337225368 1.35081100579905 0.177319640400568 46.0073937057514 13.9614200382303 3.29532336823692 0.00104736376068739 LINC00284 other 1 1 1 1.35081100579905 3.29532336823692 5.7660979937685e-06 0.0168230255394028 2.18459524528952 0.00770075169561824 0.993858572948482 -19.6559129565061 4.23160810198294 -4.64502205374246 4.26931802271603e-06 LINC01237 other 0.035767105855346 0.0526449605381113 1 0.00770075169561824 -4.64502205374246 1.56090464295322e-08 22.2657648453334 3.9235745462349 5.67486728822314 2.2910674193331e-08 -8.03944074358978 15.0464036794773 -0.534309786899792 0.593352118615118 HIST1H2BN other 0.000119253114721626 1 0.000241638880717062 5.67486728822314 -0.534309786899792 0.025755491622475 24.0620020846157 8.86476611631386 2.7143414466778 0.00685230011564577 18.6345107664612 19.6199793149183 0.949772192282195 0.342651321433888 LINC01503 other 1 1 1 2.7143414466778 0.949772192282195 0.85259310042034 -0.0575410846493362 2.31780227539353 -0.0248257089313481 0.980203172713608 3.62268199804148 6.64707121877152 0.545004240034457 0.585976031435246 LINC01694 other 1 1 1 -0.0248257089313481 0.545004240034457 4.70999552973781e-08 254.343628431764 59.8217829643118 4.25168919795485 2.4971352189502e-05 -434.215458041551 172.152312140074 -2.5222749125103 0.011944064432406 RPS28 essential 0.000349104868664167 1 0.217920114604069 4.25168919795485 -2.5222749125103 0.0422053253938596 12.9787157391374 6.71258222228575 1.93349076545358 0.0536971271320589 -6.31267896197385 13.5291794484079 -0.466597326618854 0.640975833716371 KRTAP5-AS1 other 1 1 1 1.93349076545358 -0.466597326618854 0.00129306202653489 88.0463568911568 63.1232180305165 1.39483314758432 0.163635412750718 361.86188141566 100.071133408946 3.61604659694313 0.000326958406441909 UQCRHL other 1 1 1 1.39483314758432 3.61604659694313 5.17800501533201e-05 -12.3545409149303 7.67284959604771 -1.61016331159341 0.107943348166277 -63.7818661749013 14.2512047866402 -4.47554204222043 9.29147069422974e-06 RPL13AP6 other 0.291832362664112 0.112398920988097 1 -1.61016331159341 -4.47554204222043 1.59813772531725e-30 409.757507937444 36.5417284094605 11.2134134254952 2.11650226154539e-26 -289.55993085792 137.476206564497 -2.10625487925485 0.0356388510850663 TRIM26 other 2.19711974476615e-26 1 3.05686421635001e-22 11.2134134254952 -2.10625487925485 3.23824347484937e-16 32.152659035081 3.76580571443184 8.53805572386837 1.3700397991361e-16 1.00853365604795 11.5213701039043 0.0875359134332627 0.930277752218337 RNASEH1-AS1 other 3.47593054590331e-12 1 1.8009173159644e-12 8.53805572386837 0.0875359134332627 0.000201356770954534 16.0518411357351 3.99340242296429 4.01959017288817 6.65561283581559e-05 4.09766885802637 10.6989560870748 0.382997072300977 0.701872095233113 ZNF879 other 1 1 0.559071478208509 4.01959017288817 0.382997072300977 6.75687000046378e-59 36.5088674387728 1.95643010427072 18.6609617992879 3.91073318113652e-60 17.8422564539108 22.1413167511502 0.805835382531341 0.420698491596084 TATDN1 other 1.03677413287116e-54 1 6.04403813144649e-56 18.6609617992879 0.805835382531341 1.44750027768077e-16 51.3028344806762 6.4160677808094 7.99599322097627 8.38377287709307e-15 0.843748754506026 12.8865925706217 0.0654749306212697 0.947821029618078 RNF219-AS1 other 1.56909030100595e-12 1 1.06842801545674e-10 7.99599322097627 0.0654749306212697 0.0220308369758544 -4.50568526063099 2.63076709658131 -1.7126887691754 0.0873492195916398 -18.894139937462 7.52313810355975 -2.51147056951165 0.0123164203945418 LINC01426 other 1 1 1 -1.7126887691754 -2.51147056951165 0.0586533225635324 -9.88098849139077 30.1988506650817 -0.327197501685584 0.743663263117541 -204.690300557353 86.5700810595426 -2.36444621573783 0.0184600176297708 ZNF37BP other 1 1 1 -0.327197501685584 -2.36444621573783 0.000193577668203173 37.2510234701274 15.397378600966 2.41930944451742 0.0158940876075189 -175.625404992496 62.7610418156126 -2.79831882823855 0.0053286725341793 ZNF736 other 1 1 1 2.41930944451742 -2.79831882823855 0.839874358630517 -5.92548091717105 13.7977361849919 -0.429453124608683 0.667764478811013 12.7467096297731 44.436735079242 0.286850724002168 0.774336448025202 MAGI2-AS3 other 1 1 1 -0.429453124608683 0.286850724002168 0.00709582652923697 -0.851446955630955 2.01231033785015 -0.423119108228901 0.67237466038757 -19.6343551075127 6.32311607310362 -3.1051707545004 0.00200018121498792 PINLYP other 1 1 1 -0.423119108228901 -3.1051707545004 2.80058652813116e-58 14.8946287086059 0.901000410706682 16.5312118969221 7.92218871540554e-50 -10.3986858841155 2.90618392573257 -3.57812380422353 0.000377746211479135 SP2-AS1 other 4.29357920627788e-54 1 1.21391697686159e-45 16.5312118969221 -3.57812380422353 0.0262939427720022 -10.8876590608038 31.9395049208459 -0.340883776620399 0.733323662793578 -271.202531204495 102.278574980958 -2.65160647041659 0.00824634389658729 RPL13AP20 other 1 1 1 -0.340883776620399 -2.65160647041659 0.40002229773262 -0.278359632875122 1.52272868608602 -0.182803171319121 0.855020816860789 4.69020581192495 3.95858151812763 1.18481981246236 0.236607957063881 C5orf58 other 1 1 1 -0.182803171319121 1.18481981246236 6.64655951329444e-20 25.3779997433779 4.6872205617751 5.4142960436594 9.23857231251306e-08 -98.113416622323 15.2005262703974 -6.45460656276067 2.40090929452481e-10 FAM133B other 7.85623334471403e-16 3.40857092543687e-06 0.000945752647631962 5.4142960436594 -6.45460656276067 3.55192027802465e-10 0.948859502430435 1.41313755949692 0.671455865038524 0.502217295890988 -12.7962156932706 2.32462724911708 -5.50463120404818 5.72541839164637e-08 LINC01759 other 2.98112668934609e-06 0.000763885321813459 1 0.671455865038524 -5.50463120404818 1.09733649284368e-10 20.9039728177713 4.4422510895053 4.70571617780821 3.24901189430624e-06 -71.050036509975 17.94900058331 -3.95843970143058 8.59570865289173e-05 CCT6P3 other 9.44806720338405e-07 0.973635919113047 0.0302677948073569 4.70571617780821 -3.95843970143058 1.89811827880443e-06 13.5635816374648 4.73474398676092 2.86469166556644 0.00433662653645661 -30.6473649469346 11.0453145370501 -2.77469372593528 0.00571673514276467 MCIDAS other 0.0123719349412473 1 1 2.86469166556644 -2.77469372593528 1.16126954776708e-14 39.9265650269516 8.38962387112447 4.75904112511784 2.50299965169084e-06 -93.0622613164438 18.6595275124815 -4.98738573386672 8.2712191249749e-07 MAPKAPK5-AS1 other 1.18333366917465e-10 0.010544150140518 0.0235181847272871 4.75904112511784 -4.98738573386672 5.67210575969216e-16 97.9845437560026 11.3549555487464 8.62923182176789 7.28442694587664e-17 20.4649529620818 82.3268099172692 0.248581877308828 0.803780884481821 JRK other 6.04306147637602e-12 1 9.63219775053268e-13 8.62923182176789 0.248581877308828 3.78134732409132e-09 9.57509376318919 2.06437322024703 4.63825710839409 4.40059038044491e-06 -21.0322845264925 7.57949285565186 -2.77489337704293 0.00571080980676456 SDCBP2-AS1 other 3.00163350586369e-05 1 0.0406438527537892 4.63825710839409 -2.77489337704293 0.26146093587201 24.7095942887169 15.1073453291621 1.6356013416215 0.102502537710565 20.2029350891084 42.2850501892129 0.477779617115419 0.632999340479449 LINC01287 other 1 1 1 1.6356013416215 0.477779617115419 0.000250443579613532 382.292837085294 94.139439712711 4.06092110014625 5.61481175719546e-05 -232.378213077039 710.377519377775 -0.327119322808217 0.743704873053347 GAS5 other 1 1 0.475181519011452 4.06092110014625 -0.327119322808217 0.000357435392846253 7057.82587025948 1770.19292478427 3.98703766772743 7.60053858548632e-05 5486.32621146388 6344.89373917113 0.86468370267468 0.387592143946545 HLA-B other 1 1 0.634948993431527 3.98703766772743 0.86468370267468 5.78818682327139e-11 8.33305948618667 1.21154718534135 6.87803131979448 1.67844382715217e-11 2.16146278677992 5.63941800823049 0.383277633192886 0.701664203881254 FOXP4-AS1 other 5.05424473408058e-07 1 1.97854958344698e-07 6.87803131979448 0.383277633192886 0.00669133645988881 7.59574300719533 2.3892572399943 3.17912315176805 0.00156450335854318 6.8845252758948 5.48141820468626 1.25597519087469 0.209684669117652 LINC01239 other 1 1 1 3.17912315176805 1.25597519087469 1.8119931080861e-26 666.980735316503 108.745624382939 6.13340296771653 1.71077780587545e-09 -1763.68051062153 272.936972009002 -6.46186003178552 2.39260400197264e-10 HNRNPUL2-BSCL2 other 2.38820691645747e-22 3.39701916200075e-06 1.88544821985534e-05 6.13340296771653 -6.46186003178552 0.205866348719005 41.7135487861955 23.8534605991155 1.74874201639917 0.0808965413167643 14.7742158575404 78.4975378339382 0.188212474750422 0.85077989536719 APOC2 other 1 1 1 1.74874201639917 0.188212474750422 3.41367410056488e-13 65.8330955505543 9.11957836367224 7.21887492220033 1.79655173663602e-12 -31.0121986849629 27.7515312361069 -1.1174950463495 0.264281493685074 GTF3C2-AS1 other 3.28668542402387e-09 1 2.17346829098226e-08 7.21887492220033 -1.1174950463495 5.60800143382381e-22 5.48752449632056 13.5482312062801 0.405036230395662 0.685615551430922 -221.902692277147 24.8937472246863 -8.91399315154503 8.08795902057636e-18 SEMA3F-AS1 other 6.90849696632755e-18 1.23600189752448e-13 1 0.405036230395662 -8.91399315154503 0.0038232974898678 -0.264773914587859 2.05630453526692 -0.128762014597944 0.897594172670011 -26.6814055388186 8.12113649166645 -3.28542754652601 0.00108472708654935 LINC00940 other 1 1 1 -0.128762014597944 -3.28542754652601 0.0594318422525019 22.7304631534683 12.4801016384308 1.82133638106544 0.0691182746055316 -12.8691636505624 23.7598915891015 -0.541633938113814 0.588297891284382 ANKRD65 other 1 1 1 1.82133638106544 -0.541633938113814 0.313639713602625 9.55774445664224 15.9431225680777 0.59949011969458 0.549096148081513 -64.0074596679518 55.8443112485096 -1.14617690212197 0.252226807970653 ZSCAN31 other 1 1 1 0.59949011969458 -1.14617690212197 0.56253447421848 0.100198240194615 64.1474849633969 0.00156199795287046 0.998754284380992 -198.290889149794 188.795999914316 -1.05029179240973 0.294054649413629 DSCAM-AS1 other 1 1 1 0.00156199795287046 -1.05029179240973 0.0744840967419866 28.7201360662701 23.2664310427552 1.23440230319352 0.217585987738977 -82.5055358548809 56.8925578453174 -1.45019909421548 0.147579304244059 C12orf75 other 1 1 1 1.23440230319352 -1.45019909421548 0.00779100377727483 12.0476318453172 5.91395724937797 2.03715233933833 0.0421200704485678 -11.5434823565918 10.2773919504011 -1.12319179927174 0.261853307007915 SMIM1 other 1 1 1 2.03715233933833 -1.12319179927174 1.89331722595838e-32 253.246382794557 19.5126902645989 12.9785477738051 2.15733568166411e-33 76.141782297641 134.385599032955 0.566591828630158 0.571246274057496 HGH1 other 2.64950812600615e-28 1 3.20860535933903e-29 12.9785477738051 0.566591828630158 7.49724648077789e-15 45.1421833070774 5.67159215204511 7.95934934968828 1.00653487325008e-14 -8.30350914041583 18.1282690415342 -0.458042029351584 0.647104480411518 NUCB1-AS1 other 7.70042186040697e-11 1 1.28121824016003e-10 7.95934934968828 -0.458042029351584 4.28259604306208e-16 32.8720976960282 6.55486909273223 5.0149129190811 7.2043527631968e-07 -116.701596597842 21.7723623480763 -5.36007966118352 1.23351037368261e-07 PPP1R3E other 4.57937994884628e-12 0.00162601337458842 0.00699470609778777 5.0149129190811 -5.36007966118352 1.45062742768646e-05 21.7594486953567 9.93904948749344 2.18928869634236 0.0290079685453005 -221.78888032343 56.9382164027211 -3.89525514383394 0.000110545657715016 TSPY26P other 0.0870086331126339 1 1 2.18928869634236 -3.89525514383394 0.0292597854407644 6.63459315530148 4.68838543745684 1.41511256781404 0.157608718664824 -13.7307930107885 9.23635240776992 -1.48660341275391 0.137699977293508 ITGA9-AS1 other 1 1 1 1.41511256781404 -1.48660341275391 1.41599468769363e-05 8.18537261352608 1.7148793049074 4.77314793531086 2.33407912412641e-06 4.42432030081108 4.94757248397038 0.894240623082414 0.371588617632341 SSR4P1 other 0.0850021611022485 1 0.0219823571910225 4.77314793531086 0.894240623082414 6.42242319139561e-07 3.80594428731323 2.90816182197611 1.30871131673377 0.191185770871532 32.5985742230828 6.05485526475659 5.38387340368462 1.08670463656263e-07 RPEL1 other 0.00436275207391504 0.00143640618860849 1 1.30871131673377 5.38387340368462 0.0113161127815512 19.926487719666 7.35236908513813 2.71021319644369 0.00693859655517107 39.8065098098312 19.2997270002136 2.06254263645236 0.0396355536191832 SPAAR other 1 1 1 2.71021319644369 2.06254263645236 0.244110927684839 -15.1317368209902 9.75589576078571 -1.55103510656735 0.12147695989487 -33.6728887105831 31.6353609945388 -1.06440665293486 0.287618483575502 DPY19L2P4 other 1 1 1 -1.55103510656735 -1.06440665293486 1.7523919697384e-20 8.81600856898408 2.21654074574053 3.97737266320304 7.92154245156724e-05 -37.0401732459019 5.27837996303013 -7.01733742271909 6.83324385282583e-12 SMIM27 other 2.09515983901923e-16 9.94441977901743e-08 0.660656640460708 3.97737266320304 -7.01733742271909 0.004341402196047 3.19973623458631 1.86917986703098 1.71183966349306 0.0874930400291667 -7.73716260080987 3.63203805972708 -2.13025372355026 0.0335962475686728 AGAP1-IT1 other 1 1 1 1.71183966349306 -2.13025372355026 0.952696222791817 0.24070956761081 7.91104402595756 0.0304270292038571 0.975738007955905 -22.7220005210894 74.7170605116765 -0.304107259647059 0.761166213818772 MSC-AS1 other 1 1 1 0.0304270292038571 -0.304107259647059 0.00408322417876796 10.1743789234701 13.2712071981077 0.766650597160505 0.443620020749998 -64.275683688379 25.8880194888508 -2.48283510896075 0.0133328688039334 NFAM1 other 1 1 1 0.766650597160505 -2.48283510896075 0.00834727212432519 7.87609923701129 16.0764032851438 0.489916749245125 0.624395536336325 393.000533923333 126.658334489862 3.10283990000508 0.00201894383409367 GNAS-AS1 other 1 1 1 0.489916749245125 3.10283990000508 1.35153708342566e-10 4.40035176364863 1.62890275108237 2.70142079428911 0.0071259005367555 -24.6065441654101 4.65003561289625 -5.29168940065043 1.77821472680747e-07 FAM21EP other 1.15813212678745e-06 0.00232643832708222 1 2.70142079428911 -5.29168940065043 0.000271346320975567 14.1919051274112 3.58052046332997 3.96364307165903 8.37957892125762e-05 -10.7428639726517 23.6703260514962 -0.453853654118661 0.650117526836404 LINC00494 other 1 1 0.69741152448305 3.96364307165903 -0.453853654118661 0.00092279590372491 -265.258586152709 79.8883388592526 -3.32036677618296 0.000964542030735245 -758.467258552153 310.110717701641 -2.44579505079175 0.0147963374636166 LINC00993 other 1 1 1 -3.32036677618296 -2.44579505079175 1.22703694826286e-06 10.8973139930671 4.81556159449205 2.26293730839852 0.0240314894230193 -34.4715892200628 9.96774952140528 -3.45831214418426 0.000585976554094643 DICER1-AS1 other 0.00812421163444839 1 1 2.26293730839852 -3.45831214418426 0.11026647118859 -73.3800395383919 41.3280543030552 -1.77555030779582 0.0763670842099651 -147.98126616661 76.1888940718359 -1.94229445077761 0.0526181502328449 MFRP other 1 1 1 -1.77555030779582 -1.94229445077761 1.63180120689462e-05 493.057481361771 105.317890995716 4.68161180118796 3.59819684664323e-06 -296.177764677019 757.637591618398 -0.390922741893456 0.696007394286214 KIAA0040 other 0.0973858960274711 1 0.0334416414927022 4.68161180118796 -0.390922741893456 0.7907857869918 2.31184290171263 3.5391229535597 0.653224805142005 0.513887339883419 3.1194578656476 8.08102226244003 0.38602267935167 0.699630793020929 LINC00607 other 1 1 1 0.653224805142005 0.38602267935167 0.945985431328946 0.291865513565774 1.10107058672112 0.265074298674093 0.791052635966689 1.14936325146913 4.3011222338441 0.267224038048762 0.789397943720893 IFITM4P other 1 1 1 0.265074298674093 0.267224038048762 1.50827507329795e-09 6.74844116846133 2.89951067436413 2.32744139489719 0.0203167457543039 -42.3207032220519 7.58709826798911 -5.57798274481405 3.88080350522468e-08 BHLHE40-AS1 other 1.22381439447395e-05 0.0005207650223661 1 2.32744139489719 -5.57798274481405 0.000420795875239054 13.4726605564906 9.50612200034964 1.41726148223166 0.156982123171105 -102.695547753777 33.5284245666051 -3.06293985122294 0.00230080786527965 B3GALT4 other 1 1 1 1.41726148223166 -3.06293985122294 0.0249895735355936 14.6396376443922 5.76031645609261 2.54146412892091 0.0113158894599491 -3.76947976193562 14.2348041023384 -0.264807280439946 0.791258415386472 GSN-AS1 other 1 1 1 2.54146412892091 -0.264807280439946 0.880678629181244 0.0440478422046643 3.91282345645768 0.0112573037589949 0.991022326198624 9.31721871721347 18.4847615278983 0.504048629632108 0.614433167363539 TM4SF19-AS1 other 1 1 1 0.0112573037589949 0.504048629632108 0.00120828559860312 -6.19626680723178 4.26602161457684 -1.45246962323383 0.146960591335903 -40.0774112505896 11.166015174365 -3.58923130810349 0.000362318990701847 EGOT other 1 1 1 -1.45246962323383 -3.58923130810349 6.95203221135197e-20 34.8775629200665 8.73704588349229 3.99191710621137 7.46765350843833e-05 -110.279109644881 18.4243754110674 -5.98550057651547 3.95133961096287e-09 TTC28-AS1 other 8.21243565127008e-16 5.45996107442849e-05 0.624445186375613 3.99191710621137 -5.98550057651547 3.07202787831031e-16 4.31703635978643 0.690781158283646 6.24949929224009 8.30022839772119e-10 -11.3967094907985 2.70996416909433 -4.20548346017701 3.04456106886733e-05 UBOX5-AS1 other 3.3005867524566e-12 0.355970080171968 9.26803502889548e-06 6.24949929224009 -4.20548346017701 1.46328908961385e-14 41.9032991217858 5.96496085460507 7.02490764703605 6.46464997411226e-12 -6.85562953793307 12.9377198278896 -0.529894728679662 0.596402316125287 MORC2-AS1 other 1.48523842595805e-10 1 7.70715569913663e-08 7.02490764703605 -0.529894728679662 0.0112983886064298 0.665496788059752 2.71660191679615 0.244973981629452 0.806569469009132 -23.9263096043919 8.32996602858787 -2.87231778884553 0.00423458905724903 LINC01814 other 1 1 1 0.244973981629452 -2.87231778884553 4.72280158100296e-05 25.6980427087448 11.2415214658861 2.2859932960791 0.0226552421997709 -56.1821268869576 22.5397988390025 -2.49257445855023 0.0129915793048453 MYCBP2-AS1 other 0.268024681230275 1 1 2.2859932960791 -2.49257445855023 0.427129826283636 10.6317698962538 8.14448020924136 1.30539575554376 0.192328818619864 9.56950944430235 27.7488235507439 0.34486180744934 0.730336113307908 ELFN1-AS1 other 1 1 1 1.30539575554376 0.34486180744934 3.25600766214181e-35 10.9826628441922 5.76499789074886 1.90505929964279 0.0573052705380107 -116.41138062862 10.4044217643471 -11.1886449112941 2.85469405224423e-26 COX10-AS1 other 4.651858146902e-31 4.45275178269055e-22 1 1.90505929964279 -11.1886449112941 5.17059992034085e-13 64.8287450024711 14.298836139034 4.53384767628024 7.13649422710004e-06 -225.785874877416 50.3757723409398 -4.48203301677068 9.02952371664118e-06 ZBTB22 other 4.93688880394144e-09 0.109338502684808 0.0649920529262 4.53384767628024 -4.48203301677068 2.64579430274304e-56 100.379995201271 5.63886687785908 17.8014479461133 3.06801381278465e-56 3.05122162296052 30.5915250884578 0.0997407489210712 0.92058675876822 TMEM147-AS1 other 4.04462575060328e-52 1 4.72872968964498e-52 17.8014479461133 0.0997407489210712 1.05866743345758e-05 2.64482183489742 0.720058290559877 3.67306629139838 0.000263390106140938 -4.45885244093531 2.07056039260601 -2.15345201079762 0.0317227349224151 LINC01376 other 0.0642505265365403 1 1 3.67306629139838 -2.15345201079762 2.99281257638146e-24 109.62808406276 21.4246297673281 5.11691848369487 4.32593254210511e-07 -311.98273527481 45.6537917025682 -6.83366536797994 2.24497828501249e-11 ZBED5 other 3.82391662884259e-20 3.24399362184304e-07 0.00426190874048195 5.11691848369487 -6.83366536797994 2.30421180173564e-06 3.98756609897522 0.965466195269294 4.13019753411769 4.20721410675251e-05 -3.24979577695926 2.22264022773948 -1.46213306877129 0.144294090808852 GUSBP5 other 0.0148944250864192 1 0.359843022550542 4.13019753411769 -1.46213306877129 0.217727112217853 16.0497489368609 10.4521150659358 1.53555034895935 0.125245427851961 40.1705235703689 37.0711840687119 1.08360508517646 0.279032638790146 TRHDE-AS1 other 1 1 1 1.53555034895935 1.08360508517646 0.281001995575122 1.36845570547182 0.857724458994357 1.59544908754994 0.111265918899247 -0.619432873307019 10.8669879920632 -0.0570013396314991 0.954567700651382 PPIAL4G other 1 1 1 1.59544908754994 -0.0570013396314991 2.27292061350645e-09 2.44063064457833 1.47661675880693 1.65285313878619 0.0989474248910576 -16.4997400360089 3.29364701348888 -5.00956537492799 7.42284828575148e-07 LINC00854 other 1.82775877088661e-05 0.00948565782436182 1 1.65285313878619 -5.00956537492799 2.34353070959168e-09 36.763159346474 5.83746659428539 6.29779352955329 6.27007640014256e-10 19.4022944419652 13.8624463549271 1.39962990263036 0.162199437516443 VLDLR-AS1 other 1.88349563129883e-05 1 7.03439871331994e-06 6.29779352955329 1.39962990263036 0.00908627727434422 -0.691159297076487 3.88867456087824 -0.177736471966528 0.858996964132274 -38.4020286165322 12.7240805654708 -3.01805921606181 0.00266472480241969 KCNMA1-AS1 other 1 1 1 -0.177736471966528 -3.01805921606181 0.00149444460834006 -1542.35044116637 1057.76152580222 -1.45812681170894 0.145380544450073 -7421.30560563102 2045.10961206664 -3.62880579204339 0.000311481094932386 RPL13AP5 other 1 1 1 -1.45812681170894 -3.62880579204339 0.00287355052632768 6.68744273775603 13.0423986319065 0.512746384042892 0.608336871895957 -143.916477193122 45.9126370255368 -3.13457223363308 0.00181389888135903 ZNF853 other 1 1 1 0.512746384042892 -3.13457223363308 8.21562360434432e-34 38.056078360774 4.97448027248505 7.65026219347388 9.2705084344177e-14 -61.542817615389 9.12783500578234 -6.74232362618327 4.01523922009135e-11 PITPNA-AS1 other 1.1620999588345e-29 5.77752771378944e-07 1.15482723567541e-09 7.65026219347388 -6.74232362618327 7.29893993020547e-14 -119.110198418828 37.1612991223544 -3.20522159428966 0.00143026146820158 -645.874571158302 80.6991378260122 -8.00348787555589 7.58617720042005e-15 ARHGEF38 other 7.22011137895925e-10 1.13800244183501e-10 1 -3.20522159428966 -8.00348787555589 6.08043246264337e-05 2.25162767334478 1.28389077407815 1.75375329335275 0.0800338434093046 -14.2005692831798 4.30481435729253 -3.29876461667238 0.00103438515493347 MKLN1-AS other 0.339956978986391 1 1 1.75375329335275 -3.29876461667238 0.36712155465662 -5.52367759607486 3.94936336821809 -1.39862481141285 0.162503850673763 -7.94015589781385 9.37326201009254 -0.847107003865291 0.397313551143973 CTAGE9 other 1 1 1 -1.39862481141285 -0.847107003865291 1.18020862880205e-14 9.358023573789 2.0910983692199 4.4751713795655 9.33740290084941e-06 -14.0608435115401 3.85377061453831 -3.64859378461596 0.00028956266928167 INTS6-AS1 other 1.20216050929777e-10 1 0.0843727726120753 4.4751713795655 -3.64859378461596 1.45866848352617e-21 33.1473757198348 8.48578103016484 3.90622567351245 0.000105528129739712 -80.5881845258909 13.4353808992448 -5.99820616402627 3.63700322074133e-09 ELOA-AS1 other 1.7811800852338e-17 5.02997545428526e-05 0.869762845314707 3.90622567351245 -5.99820616402627 0.00912680432436446 35.439158062835 11.7060450516029 3.02742368636129 0.00258334720505132 39.9482954290938 40.750174975658 0.980322058812184 0.327362934228163 BCYRN1 other 1 1 1 3.02742368636129 0.980322058812184 3.75871921335909e-10 89.8756532545399 15.6677231939924 5.73635697680706 1.61997853683229e-08 -102.332825889128 47.3026319546321 -2.16336431315863 0.0309552401174177 CBR3-AS1 other 3.14867908503091e-06 1 0.000171960721684748 5.73635697680706 -2.16336431315863 2.76519747071501e-11 27.4574913824454 5.1811526081022 5.29949481501623 1.69575442881031e-07 -40.7598412309452 12.7693810100994 -3.19199820247418 0.00149529558976257 NIFK-AS1 other 2.45300667627128e-07 1 0.00170847258702639 5.29949481501623 -3.19199820247418 0.576320634056948 -7.14366467576798 9.74945130981007 -0.732724791248499 0.464041311617434 9.18258433386143 22.6988611893845 0.404539428531147 0.685974804526156 LINC01554 other 1 1 1 -0.732724791248499 0.404539428531147 3.99156250721306e-07 8.02534970681319 2.25441050584476 3.5598439973584 0.000403928956215727 -10.9536589129484 4.3310518686117 -2.52909899147884 0.0117201724931512 EDRF1-AS1 other 0.0027577705362335 1 1 3.5598439973584 -2.52909899147884 4.86191975271534e-19 -0.960655010343269 4.89951143042503 -0.196071592848582 0.844627081894769 -80.8542697162339 9.53631804408006 -8.47856262160074 2.13824835001996e-16 NDUFA6-AS1 other 5.62718592179273e-15 3.24115684896026e-12 1 -0.196071592848582 -8.47856262160074 1.82199881672145e-74 270.810647048525 13.1540734333314 20.5875882038419 4.84958395693348e-70 -37.1492823931718 43.9922664625669 -0.844450295025882 0.398789716428392 PRMT5-AS1 other 2.82610236461665e-70 1 7.52606934276507e-66 20.5875882038419 -0.844450295025882 0.097077151872891 -2.23544322085339 1.0328402348335 -2.16436496706943 0.0308755403165642 -2.13282985303995 3.07131022848231 -0.694436476413487 0.487708289216965 EIF3IP1 other 1 1 1 -2.16436496706943 -0.694436476413487 0.0565355868286024 -4.90712203197383 2.08319517426041 -2.35557478848135 0.0188493712562821 -6.36860384480344 4.47143781102022 -1.42428545670646 0.154939334195152 HAND2-AS1 other 1 1 1 -2.35557478848135 -1.42428545670646 1.34537304025168e-32 39.8533472924299 3.06685560375276 12.9948561137549 9.79966941165253e-34 30.2925668346822 10.249170183994 2.95561165351609 0.00325858637470149 ZNF503-AS2 other 1.88567485321676e-28 1 1.45887678531271e-29 12.9948561137549 2.95561165351609 1.18758403260355e-10 57.8949702813917 17.6005085719168 3.28939189710509 0.00107272937788926 -114.71433681912 38.6873182572676 -2.96516641593709 0.0031654632879702 B3GNT9 other 1.01977840879667e-06 1 1 3.28939189710509 -2.96516641593709 0.0454843740731077 11.2847824078352 11.074457062155 1.01899193292274 0.30866058375182 -41.7739808410659 24.6849147007554 -1.69228783439092 0.0911647751538599 NR2F1-AS1 other 1 1 1 1.01899193292274 -1.69228783439092 6.50522062996751e-24 102.299087789638 15.4110392832942 6.63803951888772 7.68161750417264e-11 -192.579034722194 35.4864531063814 -5.4268324350388 8.63759948426879e-08 CDKN2AIPNL other 8.26683437656271e-20 0.00114595032357794 8.87610902607149e-07 6.63803951888772 -5.4268324350388 0.741399019860149 -12.7466587246761 18.9019284981371 -0.67435757816629 0.500371523663267 -36.0006973577945 74.0029567560763 -0.48647647250714 0.626826026286932 SULT1C2P1 other 1 1 1 -0.67435757816629 -0.48647647250714 3.68647936491557e-07 33.5066931130672 6.07675992902977 5.51390765875079 5.42565782456135e-08 27.6830211143058 20.1681621609744 1.37261000250547 0.170438191559099 LINC00987 other 0.00255718184825135 1 0.000562369433515784 5.51390765875079 1.37261000250547 4.07521616312288e-05 236.257349268379 58.2051701910334 4.05904404184312 5.7223776088778e-05 16.7999301680665 108.367498094134 0.155027387948674 0.876862664320218 CKMT1B other 0.233306125338785 1 0.483712579278441 4.05904404184312 0.155027387948674 0.000188244346784336 37.9553668890974 9.25311810751935 4.10190018630085 4.72603542520338e-05 14.6591225156845 50.472244141322 0.290439285295875 0.771591080509125 SMG1P1 other 0.986400377149922 1 0.402327395747564 4.10190018630085 0.290439285295875 0.00105431063937962 24.2127307921825 8.21469875594114 2.94748858254493 0.00334782874674888 -10.589529550731 15.3640772943693 -0.689239538947899 0.490980557450718 RNF223 other 1 1 1 2.94748858254493 -0.689239538947899 3.91805613050582e-08 15.5027662689442 5.03466878202586 3.07920281157128 0.0021803098001825 -26.5284166181859 9.64046568270763 -2.7517775065338 0.00612497834929721 TUSC8 other 0.000292208626213124 1 1 3.07920281157128 -2.7517775065338 4.67548214165716e-28 94.4749222293922 7.9964872638476 11.814552954585 8.36254137436934e-29 12.0442035592177 34.3387715906078 0.350746488628381 0.72591558574973 PITRM1-AS1 other 6.27917251624556e-24 1 1.22243629810531e-24 11.814552954585 0.350746488628381 0.00997604439377282 15.1437876908824 5.47993400305469 2.76349818856226 0.00591261229971219 -1.97961837114736 11.1554043012828 -0.177458236177035 0.859214643356976 FOXD2-AS1 other 1 1 1 2.76349818856226 -0.177458236177035 0.000978168360953047 41.5567399679352 11.6840900346693 3.55669460305655 0.000408877684497191 20.4795501060023 22.4609931467407 0.911782928395315 0.362293650789877 CECR7 other 1 1 1 3.55669460305655 0.911782928395315 0.0359415202073869 6.31280970066235 16.7370445816381 0.377175890873113 0.706190529613947 -134.504997126466 58.2710778568716 -2.30826341425919 0.0213600179498691 ZNF737 other 1 1 1 0.377175890873113 -2.30826341425919 3.99274971541897e-08 247.730481381277 99.0438075874227 2.50122130212546 0.012671567821185 -1499.946037465 349.270718794721 -4.29450840494468 2.07616721317131e-05 RGL2 other 0.000297459853798713 0.245818198039483 1 2.50122130212546 -4.29450840494468 5.74622954045316e-07 0.883018365335741 0.976913632038925 0.903885805639528 0.366465064769124 -8.55720762942339 2.03655951486454 -4.20179600299704 3.10540378724495e-05 LINC01637 other 0.00391720467772692 0.362897486577445 1 0.903885805639528 -4.20179600299704 2.29708408418818e-09 81.9885156964265 13.6302581889639 6.01518434645727 3.30757884449285e-09 -34.9092777406785 70.1479792007098 -0.497651937211118 0.618931226390992 SHISA9 other 1.8468556036873e-05 1 3.6059224562661e-05 6.01518434645727 -0.497651937211118 0.00382644101885491 20.8564028769455 6.41866531637059 3.24933640390191 0.00122886785228935 30.5335403973438 12.5933894165615 2.42456890574586 0.0156543223776105 DGCR5 other 1 1 1 3.24933640390191 2.42456890574586 0.00466526393169326 4.99737883762619 1.63308423816244 3.060086381857 0.00232205160964004 10.5737652588632 6.00156891306185 1.76183351587456 0.0786600959865008 LINC00857 other 1 1 1 3.060086381857 1.76183351587456 1.19962637258372e-15 338.526351954134 40.6031858180531 8.33743326129887 6.31486592505314e-16 117.198653659546 143.047785511955 0.819297224630939 0.412977627982905 KIFC1 other 1.26512597252679e-11 1 8.20869421597657e-12 8.33743326129887 0.819297224630939 1.68670524183259e-05 54.5850765181082 11.7771418742034 4.63483221151229 4.48030452178792e-06 -7.14271652900071 42.9107545514633 -0.166455160335957 0.867860844382721 C2orf74 other 0.100510765360804 1 0.0413487304315807 4.63483221151229 -0.166455160335957 1.5271278144591e-06 24.0198618040418 4.63412647281802 5.18325555958237 3.07854749961616e-07 14.2221013261558 10.8295075961568 1.31327312898354 0.189644577476479 P4HA2-AS1 other 0.0100225398462951 1 0.0030597683598685 5.18325555958237 1.31327312898354 0.0336870757717923 1.54067479902844 0.945698082315825 1.62914023813566 0.103865443248886 -5.75567048435958 3.23633252202465 -1.77845460724129 0.075890726624835 DCTN1-AS1 other 1 1 1 1.62914023813566 -1.77845460724129 0.549242676062645 -0.271589600549309 5.90297970484098 -0.046008899594654 0.963320718601865 -11.3763524976689 11.2985321081616 -1.00688765485306 0.314454376077914 AMY1A other 1 1 1 -0.046008899594654 -1.00688765485306 9.94523790241046e-16 37.2741189528299 11.7657136455563 3.16802873805344 0.00162108920235304 -122.07893268229 22.4630281946358 -5.43466052860331 8.30372072570591e-08 FAM200B other 1.052106717696e-11 0.00110215285192295 1 3.16802873805344 -5.43466052860331 6.74017595346844e-13 29.8215405076123 4.37074139483567 6.82299358704875 2.38744043521286e-11 -36.0014294162361 14.8276776571214 -2.42798840443806 0.0155067102884652 DGUOK-AS1 other 6.40653724377175e-09 1 2.80118386263525e-07 6.82299358704875 -2.42798840443806 0.0599563324937942 178.443305830156 138.150857793896 1.29165543145864 0.197025003951562 -378.227554434626 267.6011908371 -1.41340011698554 0.158110051303378 LINC01238 other 1 1 1 1.29165543145864 -1.41340011698554 0.000104018975638783 32.2254806338592 9.22870622722467 3.49187414144727 0.000519068124643252 -49.7431651211321 28.0446928699998 -1.77371046107422 0.0766766452994162 LINC00649 other 0.56336677205965 1 1 3.49187414144727 -1.77371046107422 0.52707193288147 -13.2951361725016 15.7230742866959 -0.845581209506295 0.398160234151915 -40.5375546734709 40.8849077357716 -0.991504125078487 0.321882725074488 PTENP1 other 1 1 1 -0.845581209506295 -0.991504125078487 0.00780428938451021 6.24706691964481 2.34575383454012 2.66313831726914 0.00798340938143602 15.2136811190369 6.87876429828579 2.21168809677462 0.0274256638633055 LINC01679 other 1 1 1 2.66313831726914 2.21168809677462 0.325789673915773 0.066083054018628 1.00655086613045 0.065652970199783 0.947678825717083 -3.27200721308205 2.35177910563897 -1.39129019610584 0.164720064481797 ZEB2-AS1 other 1 1 1 0.065652970199783 -1.39129019610584 1.45418418591046e-18 26.16069691656 9.21043601430383 2.84033208372897 0.00468464604566518 -167.252189970616 22.8896929395652 -7.3068778341503 1.04571927926687e-12 LRRC37A2 other 1.66329587184439e-14 1.5360570493151e-08 1 2.84033208372897 -7.3068778341503 0.104844148701964 3.07324964925221 1.44425113644917 2.12791914902563 0.0337935780725428 4.82648864165207 6.5912285125718 0.732259340189201 0.464326229392257 ABCA17P other 1 1 1 2.12791914902563 0.732259340189201 8.28293950058506e-10 37.1712392654656 18.1874266465529 2.04378772147575 0.041460079320945 -242.865495768718 44.8939051423648 -5.40976542358161 9.50443109469775e-08 GOLGA2P5 other 6.80609138763074e-06 0.00125886189849272 1 2.04378772147575 -5.40976542358161 0.00915899352475845 -19.0531748116419 12.0163493515127 -1.58560426750936 0.113484917453833 -93.2737837200182 31.2132678311011 -2.98827358368032 0.00294875501900784 LINC01410 other 1 1 1 -1.58560426750936 -2.98827358368032 0.277186516937659 1.73912300639524 1.09817077872121 1.58365441886953 0.113874551672009 2.27396038640369 2.38230407929234 0.954521467754512 0.340259033406052 LINC00426 other 1 1 1 1.58365441886953 0.954521467754512 0.000286319758134227 5.88223792332809 5.35337062199147 1.09879146031176 0.272345986709181 -45.0750960092327 13.1699315249006 -3.42257633792616 0.000667073629630475 MAP3K20-AS1 other 1 1 1 1.09879146031176 -3.42257633792616 6.54456697412996e-09 6.47943195246195 2.49632781741076 2.59558536634125 0.009697068446943 -18.8084488994852 4.98517126891462 -3.77287918205871 0.000179020784121926 CD81-AS1 other 5.12439594074376e-05 1 1 2.59558536634125 -3.77287918205871 1.45103327433768e-10 12.5734042141818 2.11498926382875 5.94490214641578 4.97835134073731e-09 -14.2857613874154 6.59034982311123 -2.16767876832846 0.0306209643001536 PAXBP1-AS1 other 1.24266489614279e-06 1 5.39155450201851e-05 5.94490214641578 -2.16767876832846 3.99498173793509e-16 210.955932157703 29.4935609638006 7.15260976511529 2.90054853961314e-12 -160.211747946368 68.2684818298753 -2.34678937706004 0.019309527381633 TMEM250 other 4.27622845228572e-12 1 3.49023005771649e-08 7.15260976511529 -2.34678937706004 0.0396869864508874 45.7298491817152 19.376132124971 2.36011237365484 0.018621454768237 111.496464948231 85.1878194667624 1.30883107052334 0.191144204344946 LINC00707 other 1 1 1 2.36011237365484 1.30883107052334 0.802847310479827 2.44859149427199 3.70175702611758 0.661467372654679 0.508593726579616 1.98453947365082 12.8189980642143 0.154812370179764 0.877026871091467 SCARNA12 other 1 1 1 0.661467372654679 0.154812370179764 0.868286369999301 -11.490711467493 22.427677506264 -0.512345135348219 0.608618579522464 1.83578906135827 84.9775882911907 0.0216032144271689 0.982772434683911 SCARNA10 other 1 1 1 -0.512345135348219 0.0216032144271689 5.23405966463575e-18 1608.21574660738 178.799571748276 8.99451677027237 3.97160083345621e-18 364.563741895875 559.714888204389 0.651338296655687 0.515104192284556 TXNDC5 other 5.90768314347438e-14 1 5.34736336216545e-14 8.99451677027237 0.651338296655687 2.03363959240114e-09 11.2034655577382 10.7655362084681 1.04067882368234 0.298488626796852 -119.234523496731 23.175546934483 -5.14484183841724 3.74857149944252e-07 CASTOR1 other 1.64033369523076e-05 0.00484577837732935 1 1.04067882368234 -5.14484183841724 0.00340287535843583 -89.1546625732285 53.7846737820069 -1.65762207528819 0.0979724110134295 -615.119579555355 192.571889117601 -3.1942335009224 0.00148351957347079 RNF103 other 1 1 1 -1.65762207528819 -3.1942335009224 3.10271956279866e-05 79.6289054275619 18.015776629606 4.41995408050879 1.20594268127835e-05 -3.23467484678164 64.2021553759536 -0.0503826519193959 0.95983710931978 RBM14 essential 0.179709517077299 1 0.107968048254851 4.41995408050879 -0.0503826519193959 0.268848671851267 2.58677511038945 1.59416275162915 1.62265434175143 0.105242654470793 1.40189961390486 5.49607755733982 0.255072749479795 0.798763313166836 LINC01119 other 1 1 1 1.62265434175143 0.255072749479795 3.83398251260054e-11 36.9329772703387 5.81194389351317 6.35466858370061 4.43806481309439e-10 -48.0456016363019 26.8053442847949 -1.79238890296796 0.0736293092966801 ALKBH6 other 3.37888878835485e-07 1 5.01057517398357e-06 6.35466858370061 -1.79238890296796 9.25243957243063e-12 7.32018066446452 4.06363485812795 1.80138740807948 0.0721944251324789 -40.6779720346404 7.60197828042771 -5.35097188311774 1.29035922164473e-07 ASB14 other 8.4030656196815e-08 0.00169914502306179 1 1.80138740807948 -5.35097188311774 0.000175031443821461 12.0925666343791 36.8395147982888 0.328249888756427 0.742853854406818 -359.102073813342 94.4843471385183 -3.80065148025928 0.000161266434633856 PCDHA13 other 0.920315331613241 1 1 0.328249888756427 -3.80065148025928 0.514791243277186 -6.47394000483006 7.30822169522053 -0.885843406893899 0.37609621831846 -19.3226740337445 20.4591419164311 -0.944451830515244 0.34536118142776 CYP4F62P other 1 1 1 -0.885843406893899 -0.944451830515244 0.75414716897277 291.046566013733 461.297545696292 0.630930228719126 0.528351124418448 -248.825778230816 1180.00047399293 -0.210869218881609 0.833068287914236 KLHL41 other 1 1 1 0.630930228719126 -0.210869218881609 9.8497979285758e-05 10.2499346488508 9.9208590745453 1.03317006842178 0.301987656270143 -119.727881755799 32.0644821516919 -3.73397210001351 0.000208539401521253 GATS other 0.535533513376666 1 1 1.03317006842178 -3.73397210001351 0.0779784851046753 -0.294836957401251 3.12716721336543 -0.0942824407153942 0.924919513645555 -23.1945278109685 10.3625720548371 -2.23829833831086 0.025605366473565 MYLK-AS1 other 1 1 1 -0.0942824407153942 -2.23829833831086 0.000683520096693043 0.831974261479945 0.842899664220679 0.987038311670422 0.324071705994371 -4.65173150043876 1.62700859525635 -2.85907002212599 0.00441521783306867 PSMD6-AS2 other 1 1 1 0.987038311670422 -2.85907002212599 4.10588648424824e-49 946.684320109381 58.0687372570902 16.3028225655758 1.88548566853357e-48 -42.2964474564939 226.597163645906 -0.186659209567993 0.852001632344059 NME1 other 6.19331917284005e-45 1 2.88517016999007e-44 16.3028225655758 -0.186659209567993 1.67437033281922e-22 -22.3412194303177 21.966334404481 -1.01706634429458 0.30957315404659 -386.623172421182 39.2643244433309 -9.84667832447199 3.65019993813583e-21 TNFSF12 other 2.08191207182742e-18 5.64174902438274e-17 1 -1.01706634429458 -9.84667832447199 6.39281536016364e-28 10.8840233881536 11.1476257343403 0.976353498720839 0.329325686700767 -204.208355474571 20.2394539789505 -10.0896178171087 4.74700399217127e-22 CDRT4 other 8.56956899029935e-24 7.35405858467173e-18 1 0.976353498720839 -10.0896178171087 0.151439249310145 -11.7328944312293 14.7784501466438 -0.793919140018467 0.427588677079131 -59.5628651591215 30.6671094093926 -1.94223930152604 0.0526238900674687 APOBEC3G other 1 1 1 -0.793919140018467 -1.94223930152604 2.33174418262917e-07 4.73180514919553 0.882664514294184 5.36081951020687 1.22699958281947e-07 -4.51945887832038 3.46529226184172 -1.30420713083473 0.192715525634451 HLTF-AS1 other 0.00164061520689788 1 0.00124614077631146 5.36081951020687 -1.30420713083473 0.232660669465004 1.58202931757231 1.7331785009163 0.912790757983625 0.36177478319382 5.41321460497654 3.16941410721797 1.7079543479814 0.0882404997652158 TLR9 other 1 1 1 0.912790757983625 1.7079543479814 0.00265020793669987 -5.65486941227468 57.6981581798254 -0.0980077976605489 0.921962468872525 -678.862708257955 197.409937504302 -3.43884769348636 0.000629302153030912 WBP1 other 1 1 1 -0.0980077976605489 -3.43884769348636 2.19902461944635e-12 93.9751808484653 13.1266558219848 7.15911060081836 2.75367592148192e-12 -52.6155550565093 56.8462600322805 -0.925576370840073 0.355091432291711 MRPS17 other 2.04949094532399e-08 1 3.31542580946424e-08 7.15911060081836 -0.925576370840073 2.27840929905057e-18 -0.19072625273652 0.587927105500635 -0.324404591916393 0.745756214072801 -9.03168893249511 1.11004783419993 -8.13630607099444 2.7738661043567e-15 SUGT1P3 other 2.59670307812793e-14 4.17605542010901e-11 1 -0.324404591916393 -8.13630607099444 2.03729948862522e-16 263.541070511455 34.8445068350104 7.56334626170286 1.80797660509249e-13 -299.362566263112 125.749157149103 -2.38063278553949 0.0176442480807265 GET4 other 2.20007971776638e-12 1 2.23881743008602e-09 7.56334626170286 -2.38063278553949 0.581162517854257 26.139802191191 41.3121612786956 0.632738675056226 0.527173142140337 306.749773172581 390.847563562692 0.784832251163255 0.432897377150985 C1orf226 other 1 1 1 0.632738675056226 0.784832251163255 3.71818346763775e-33 314.634428135446 31.7956581727014 9.89551549543262 2.44726914136089e-21 -153.657201583043 58.8877361148195 -2.60932431301896 0.00932227113544044 ADSL essential 5.2337150490469e-29 1 3.40513028328954e-17 9.89551549543262 -2.60932431301896 0.934483897303756 0.17289448347887 2.04791996367813 0.084424433837905 0.932750386401186 3.18374040147615 8.65262556230722 0.367950788873291 0.713054645765286 LILRA4 other 1 1 1 0.084424433837905 0.367950788873291 0.000373626439730851 -4.25119154250667 2.19110533016764 -1.94020409880588 0.0528684481099386 -41.2928520154645 11.053336662038 -3.73578162667225 0.000206781534117705 LILRA2 other 1 1 1 -1.94020409880588 -3.73578162667225 0.000410600050432631 7.93577176477996 2.19679550121051 3.61243081588936 0.000331550307794105 13.9483093756564 9.3377311943568 1.49375786101938 0.135820827105695 LINC00888 other 1 1 1 3.61243081588936 1.49375786101938 0.0435617909074731 -9.19083714036815 29.1441749286491 -0.315357602775484 0.752616185652333 -132.925427491974 55.7918802646047 -2.38252281266642 0.0175514742494754 AMY2B other 1 1 1 -0.315357602775484 -2.38252281266642 9.50513262742e-23 246.98157994504 27.1070425087788 9.11134366152459 1.55216698078127e-18 -194.058534919808 93.5717807646481 -2.07390020082982 0.0385584703633159 LY6G5B other 1.18700096251221e-18 1 2.10023714169513e-14 9.11134366152459 -2.07390020082982 4.5895024874805e-05 199.184360087381 45.0089430610418 4.42543962468179 1.16249119000477e-05 355.233171394728 158.052912949253 2.24755852180202 0.0250027539914996 PSMB9 other 0.261280376612265 1 0.104205710272027 4.42543962468179 2.24755852180202 3.68865128501131e-05 3.30447664514479 0.909473977084562 3.63339328931403 0.000306221851512335 -9.87326741144867 3.9382005998492 -2.50705040566667 0.0124647539120819 ERICH6-AS1 other 0.21202367586245 1 1 3.63339328931403 -2.50705040566667 0.00951803583015739 30.1296750722851 87.8690702065206 0.342892840466738 0.731812269605319 -584.513487983599 214.247476207758 -2.72821644543804 0.00657478976544397 PCDHGC3 other 1 1 1 0.342892840466738 -2.72821644543804 1.05974861335472e-09 24.0724481966617 4.38116153682066 5.49453563726178 6.01661797769252e-08 -29.7403835511182 16.1566065410815 -1.84075681211257 0.0661996202462777 SMKR1 other 8.66238516556148e-06 1 0.000622539462151845 5.49453563726178 -1.84075681211257 0.215423461849389 123.331535057114 70.6348852303108 1.74604283216404 0.0813648974308799 98.727367632404 138.81956782909 0.711192011157633 0.477268410792295 UGT1A5 other 1 1 1 1.74604283216404 0.711192011157633 5.11123305382018e-10 75.3885351882669 12.1620594180727 6.19866525863541 1.12342633452915e-09 -76.6830629874329 54.3729252150223 -1.4103170407732 0.15901551278723 ZNF542P other 4.25407927069454e-06 1 1.24812665766189e-05 6.19866525863541 -1.4103170407732 3.28798468356707e-15 82.5736490547659 11.9579051746137 6.90536075081677 1.47449983414692e-11 -124.200604558935 43.1544778089875 -2.87804674890699 0.0041670118273792 COX19 other 3.41818887703633e-11 1 1.74108940416068e-07 6.90536075081677 -2.87804674890699 1.73379415976252e-11 4.77038441174953 0.710070565352294 6.71818357853314 4.67169496405537e-11 -3.30857162227309 2.22811510517087 -1.48491952439744 0.13814756706609 B4GALT4-AS1 other 1.55226591123538e-07 1 5.42850954823234e-07 6.71818357853314 -1.48491952439744 4.58781590711639e-12 13.829252621983 3.35691940275165 4.11962605079145 4.40838363014924e-05 101.629149713458 14.9181629742367 6.81244399119178 2.63685032286089e-11 TCAM1P other 4.22308454250063e-08 3.80497501588826e-07 0.37634371050584 4.11962605079145 6.81244399119178 4.12570637466296e-09 3.57456475414169 0.573479435711719 6.23311758285711 9.1526895607231e-10 3.24071933110191 1.75578416232823 1.84573901544061 0.0654712851352535 GHRLOS other 3.2671468780956e-05 1 1.02052488602063e-05 6.23311758285711 1.84573901544061 2.74069556869145e-05 35.1928075345584 11.0155384286106 3.1948331679505 0.00147989235181134 -104.347447825633 37.8413874752113 -2.75749529252825 0.00601963163869361 ACAD11 other 0.159645516876277 1 1 3.1948331679505 -2.75749529252825 6.92666048378226e-06 11.3478946095573 8.81510881230262 1.28732325955181 0.198534141398191 -94.6123691547774 22.0938129392164 -4.28230153912641 2.19012504919439e-05 PPIL3 other 0.0426751552405825 0.258894682065269 1 1.28732325955181 -4.28230153912641 2.12729580715569e-18 11.0518840361342 1.57974760849301 6.99598086220685 7.88888739403678e-12 -21.7786091728705 5.5395773264222 -3.93145684039696 9.5506532557492e-05 RPL13P5 other 2.42596813848034e-14 1 9.38619822142496e-08 6.99598086220685 -3.93145684039696 3.217741031909e-10 14.4448617777433 2.13921208114374 6.75242155982041 3.9054135007693e-11 11.7374806771656 4.90552843163487 2.39270464757124 0.0170792468527512 CDKN2B-AS1 other 2.70579843373228e-06 1 4.55019726974631e-07 6.75242155982041 2.39270464757124 0.383830844161674 0.689418899429247 0.651985614691716 1.05741428015284 0.290796233533824 -1.0972515254931 2.07473910437443 -0.528862411268784 0.597118608483081 TNFRSF13B other 1 1 1 1.05741428015284 -0.528862411268784 0.00462401369801001 15.4781851965015 4.71725301201366 3.28118613885719 0.00110021214123975 -2.46253786590108 18.7998561824725 -0.130987058730638 0.895834148619129 TM4SF1-AS1 other 1 1 1 3.28118613885719 -0.130987058730638 0.26545070604682 -2.51826427426497 1.56486350079367 -1.60925491136304 0.108142873312281 -0.982371606381932 3.55175251707176 -0.276587853928474 0.782202033258402 L1TD1 other 1 1 1 -1.60925491136304 -0.276587853928474 0.471568469756476 4.32474752443192 124.225023678973 0.0348138192801484 0.972241113642424 -573.080078200045 468.187635019946 -1.22403932811175 0.221473151711439 LINC02067 other 1 1 1 0.0348138192801484 -1.22403932811175 0.721155820979339 -113.012937731886 215.252257138915 -0.525025564117326 0.599779713230184 -642.485086804218 902.377255533363 -0.71199166741461 0.476775720936816 AQP1 other 1 1 1 -0.525025564117326 -0.71199166741461 0.00780990322137069 0.511910578815619 1.29378428751045 0.395669188254448 0.692503359003333 -7.19713006235906 2.81515242205523 -2.55656852040172 0.0108399331757562 C1QTNF9 other 1 1 1 0.395669188254448 -2.55656852040172 1.64086241514838e-18 149.739115941929 17.0217929838219 8.79690618281206 1.89294081203141e-17 -92.2281404527902 56.7038119361254 -1.62648924831864 0.104428990354861 ISY1 other 1.87517756803157e-14 1 2.52423657284389e-13 8.79690618281206 -1.62648924831864 0.000639351415915998 -44.6206990220777 23.5646599515332 -1.89354309011256 0.0588150539977864 -181.07442306684 47.6802042395135 -3.79768555850229 0.000162472075051207 PNMA2 other 1 1 1 -1.89354309011256 -3.79768555850229 9.70231134528286e-06 332.538064118421 100.805107885914 3.29882156859322 0.00103417947124563 -858.076834426931 334.173832901978 -2.56775591007638 0.0105008908644516 LRRD1 other 0.0590870760927726 1 1 3.29882156859322 -2.56775591007638 0.387305175845647 -0.21153125972498 5.46825038165035 -0.0386835358590764 0.969156813859526 12.5139758300131 10.4448865840658 1.19809590360741 0.23139853894108 KRBOX1 other 1 1 1 -0.0386835358590764 1.19809590360741 0.00427312352623598 58.3891900132972 81.1687790117219 0.719355283203965 0.472233232450448 -530.296089189969 191.356958387631 -2.77124016632701 0.00577685158276033 PCDHGC5 other 1 1 1 0.719355283203965 -2.77124016632701 0.200635027871215 -0.159356278260648 14.7394765504044 -0.0108115290061828 0.991378010897609 -73.2641229619106 42.0206001342711 -1.74352871514936 0.0818391947517673 ARHGEF25 other 1 1 1 -0.0108115290061828 -1.74352871514936 4.21204601897999e-34 290.371597003623 21.9239698851603 13.244480745258 8.59820500145031e-35 497.701044113408 167.852108161956 2.96511643233692 0.00316195297940681 TMEM189 other 5.96931161809845e-30 1 1.28396995286658e-30 13.244480745258 2.96511643233692 7.86107553606476e-16 67.5090227908975 10.4136120303395 6.48276722756847 2.02804513891914e-10 -116.881695008843 30.1211564966739 -3.8803853703874 0.000117128331008802 RDH14 other 8.33902892865749e-12 1 2.31318828545118e-06 6.48276722756847 -3.8803853703874 0.0547396467156228 0.419501791878221 4.74546470820381 0.0884005714241219 0.929591141509779 -43.8558694386349 18.1949506320449 -2.41033187314046 0.0162718285417649 LINC00886 other 1 1 1 0.0884005714241219 -2.41033187314046 7.29404536784252e-12 49.8078421598082 9.33464092288945 5.33580697653559 1.39812032082773e-07 -94.5341953051075 30.6426547719231 -3.08505238885915 0.00213861114740464 NDUFB2-AS1 other 6.65946342084022e-08 1 0.00141475795264558 5.33580697653559 -3.08505238885915 0.57426163623236 3.23773967017816 4.31390283407523 0.750536067851013 0.453257607806306 -9.24362008980337 14.6855596380539 -0.629436011811964 0.529328866775746 PLCXD2 other 1 1 1 0.750536067851013 -0.629436011811964 2.93180159112133e-17 2836.45847878304 380.045644371994 7.46346793020123 3.33892564709246e-13 -806.161297844993 865.171465296674 -0.931793673487087 0.351854239219543 MIF other 3.2452111812122e-13 1 4.10654465335902e-09 7.46346793020123 -0.931793673487087 0.106992899343276 2.27875483110541 1.25809225999988 1.8112779988851 0.0706724757022165 7.37427164523733 5.26991406978338 1.39931534890102 0.162312378792999 HOXA11-AS other 1 1 1 1.8112779988851 1.39931534890102 2.46246449811405e-11 38.7539270845646 5.46157070347671 7.09574757677214 4.04537977446213e-12 49.2689669927469 22.9080140251518 2.15073061063487 0.0319389448571294 TPM3P9 other 2.19036217107245e-07 1 4.85121942553498e-08 7.09574757677214 2.15073061063487 7.8918310566719e-12 30.5527664055661 4.91450111866403 6.21686019961098 1.01569381772921e-09 -55.2051849397737 19.5047748488071 -2.83034207611732 0.00482298237497787 NSUN6 other 7.19261482505077e-08 1 1.13097506604147e-05 6.21686019961098 -2.83034207611732 0.0119774203926476 23.9253247150923 9.99334469017414 2.39412583642959 0.0169963880600983 86.3160816994531 35.0925200853054 2.45967179016012 0.014215276132469 HLA-DOB other 1 1 1 2.39412583642959 2.45967179016012 4.00858135673531e-07 -17.060475927594 14.1549263242634 -1.20526773059568 0.228633788176357 -145.344854771383 27.2661213976086 -5.33060249574516 1.44675089322142e-07 PRICKLE2-AS1 other 0.00276872714309708 0.00190218807440753 1 -1.20526773059568 -5.33060249574516 0.218021842265888 123.007113542592 70.7272731145241 1.73917511768642 0.0825665225266007 98.4903314965635 139.001138820779 0.708557730764722 0.478900818302947 UGT1A9 other 1 1 1 1.73917511768642 0.708557730764722 5.26622409380536e-14 31.2532087633621 4.86370432396335 6.42580360187158 2.85613077636207e-10 -55.8667459067818 18.3469610509902 -3.04501359933757 0.00243871794980881 YAE1D1 essential 5.23410012683315e-10 1 3.24485017502495e-06 6.42580360187158 -3.04501359933757 0.843156322894867 1.34849928814263 2.31495344204101 0.582516807315878 0.560464498298437 1.35821638531358 4.45921088775336 0.304586712649931 0.760799606835001 ADAMTS9-AS1 other 1 1 1 0.582516807315878 0.304586712649931 3.85677680151275e-24 204.39115785499 23.1848773372175 8.8157101235507 1.71820946554987e-17 -383.108386846596 87.646481536625 -4.37106407616038 1.48900258074729e-05 CRCP other 4.91970448800966e-20 0.177920918373493 2.29243506893663e-13 8.8157101235507 -4.37106407616038 4.99086876410658e-15 34.8953360345285 4.20765196290458 8.29330380510843 8.66031162452367e-16 26.5935875979919 16.5156655802665 1.6102038073335 0.107932375902542 WWTR1-AS1 other 5.15456925956927e-11 1 1.12280940211949e-11 8.29330380510843 1.6102038073335 5.83471317162192e-06 1.88625816762548 1.02934178870552 1.83248964369513 0.0674341342621474 -6.60090327876957 2.00899709529152 -3.28567089232736 0.00108406208810208 SUCLG2-AS1 other 0.0361635522377126 1 1 1.83248964369513 -3.28567089232736 4.39484102663742e-05 5.14790834583999 1.13858283546995 4.52132966128477 7.55830005092807e-06 4.2214277702007 2.06333314146853 2.04592641166816 0.0412474789551987 CDRT1 other 0.250813577390197 1 0.0687049474629362 4.52132966128477 2.04592641166816 6.55249390722906e-23 100.237492662487 11.4542556358105 8.75111363405446 2.65660202888005e-17 -28.559332822604 23.5605633755228 -1.21216680464757 0.225974729873166 PDXP other 8.19913562611572e-19 1 3.53540598003357e-13 8.75111363405446 -1.21216680464757 1.19643895127123e-19 147.391873541221 15.6849808549197 9.39700691410092 1.53232936219677e-19 21.6590999453876 59.405153896377 0.364599677380998 0.715551680961837 RPP21 essential 1.4076104261706e-15 1 2.09729919803872e-15 9.39700691410092 0.364599677380998 0.00670911300029097 -16.059646650846 46.1006683541744 -0.348360386610139 0.727703824212807 -358.704619212081 115.349046965795 -3.10973197133088 0.00197026767995656 CD302 other 1 1 1 -0.348360386610139 -3.10973197133088 0.00129439315786219 10.6778682547399 9.08404198317717 1.17545342420415 0.240329451027476 -91.8118525859161 31.6087961933626 -2.90462983861421 0.00382690645071616 EGFL8 other 1 1 1 1.17545342420415 -2.90462983861421 1.00810410514774e-16 352.547379403655 56.6970735763245 6.21808776301413 1.00830862624661e-09 -776.226763569896 179.737400018681 -4.31867136994981 1.8682071520492e-05 ATP5J2 essential 1.0985310433795e-12 0.221868281377364 1.1231549787761e-05 6.21808776301413 -4.31867136994981 1.34591527703713e-07 3.56890443976136 5.2831522766262 0.675525567481929 0.499634876511603 -47.2849634935741 10.0997971809751 -4.68177356894297 3.61245288015038e-06 PTPRG-AS1 other 0.00096502125363562 0.0446607549572992 1 0.675525567481929 -4.68177356894297 2.73287578376762e-15 100.458831998864 29.9115202603314 3.35853313788576 0.000838231294813633 -305.222730582555 59.7856802724855 -5.10528155222856 4.56900062428008e-07 ARHGAP8 other 2.84765656668586e-11 0.00588807110450974 1 3.35853313788576 -5.10528155222856 0.76830622136044 -1.70558656761797 2.93030850373971 -0.582050171659834 0.560778072474094 -6.72116403146608 11.5923744215247 -0.57979183444819 0.56229908052985 GUSBP2 other 1 1 1 -0.582050171659834 -0.57979183444819 1.49512120742593e-49 1128.55366429917 67.6786192607927 16.6751874761274 1.19928496792255e-50 278.644279769826 204.033431157464 1.36567952707113 0.172609183479074 ARPC4 essential 2.25793204745464e-45 1 1.83886364131564e-46 16.6751874761274 1.36567952707113 2.42256072859638e-10 4.9202341173301 1.36939514812185 3.59299806493276 0.000356610379649557 -7.00075423383809 2.21875410971333 -3.15526366945754 0.00169236793090094 CORT other 2.05360472963115e-06 1 1 3.59299806493276 -3.15526366945754 2.77570394673105e-06 4.72512000101785 0.992428360799828 4.76116986137895 2.4699826436746e-06 -4.37340873401712 3.52944125208497 -1.23912212207346 0.215833636773807 PAQR9-AS1 other 0.0177811594827591 1 0.0232227768158286 4.76116986137895 -1.23912212207346 0.191316066623675 142.957181255635 78.6403581727942 1.8178602511133 0.0696323756555991 104.535510493457 152.197047538688 0.686843221888941 0.492472599244584 UGT1A1 other 1 1 1 1.8178602511133 0.686843221888941 0.184138875916281 -11.4250112434944 9.21678217485058 -1.23958785471456 0.215663335744309 -61.5712788203138 38.6384547801654 -1.59352332205378 0.111624731769899 INMT other 1 1 1 -1.23958785471456 -1.59352332205378 0.893950677228811 -0.424614896348765 1.56675350794581 -0.271015762336146 0.786483440324257 -1.41554263621807 3.0166281071099 -0.469246650882079 0.639084513343164 ADAMTS9-AS2 other 1 1 1 -0.271015762336146 -0.469246650882079 6.24714665223996e-25 584.359990455178 71.2368748188274 8.20305483559388 1.71756320130364e-15 -1102.77549067217 225.868457419055 -4.88237934270824 1.38173950353507e-06 ARPC1A other 8.06569104270701e-21 0.0174347890556056 2.2156565296817e-11 8.20305483559388 -4.88237934270824 6.63867755872344e-08 28.2129488533282 7.53470992067037 3.74439748183671 0.000200168436926997 85.8227566260607 15.7265127372734 5.45720199130049 7.36962328768899e-08 TMEFF1 other 0.000486415904727667 0.000979938808564005 1 3.74439748183671 5.45720199130049 0.389742283592988 -3.17022457144525 2.45732913784498 -1.29010986872742 0.197560636162191 -11.7310259594611 28.4904297808179 -0.411753211506812 0.680682500887103 SPRR2A other 1 1 1 -1.29010986872742 -0.411753211506812 3.13139703910424e-21 659.463956780827 72.0509673782098 9.15274257622621 1.14259439024137e-18 -533.697099442267 218.965496722273 -2.43735706050158 0.0151173802061416 ATP5O other 3.80026344665691e-17 1 1.54844391765511e-14 9.15274257622621 -2.43735706050158 0.695117622555805 25.3719914155379 29.78679832197 0.851786457251571 0.394710909647184 12.3891155236466 67.6805714650995 0.183052761752097 0.85482545389842 PLEKHO2 other 1 1 1 0.851786457251571 0.183052761752097 1.51193254124116e-34 33.0024093667643 6.53584597483357 5.04944723205547 6.11087137962646e-07 -86.2707385992998 13.2607367989823 -6.50572738959125 1.79738835837931e-10 C8orf58 other 2.15027046015318e-30 2.55750389513792e-06 0.00595441096476781 5.04944723205547 -6.50572738959125 0.0665821711465555 3.6199424883808 3.17331950601303 1.14074314972743 0.254476017153922 -8.61808483432762 6.16390826497996 -1.39815267584221 0.162633857710416 HOGA1 other 1 1 1 1.14074314972743 -1.39815267584221 1.81083739559844e-30 251.200296125687 68.6198480129665 3.66075273262366 0.000276579227242454 -1231.72865763575 144.490877444875 -8.52461192995153 1.59178521115331e-16 PI4KA essential 2.48754733033358e-26 2.41457898679846e-12 1 3.66075273262366 -8.52461192995153 0.829287714042361 -57.1683347739882 115.614497284704 -0.494473756463341 0.621169799405095 -124.190824529963 245.661856340189 -0.505535643099535 0.613385939983463 AKAP2 other 1 1 1 -0.494473756463341 -0.505535643099535 4.55376158777024e-17 306.557567620177 61.7935473320611 4.96099642852388 9.53715228821358e-07 -447.48208108931 107.079979738845 -4.17895186551833 3.43951947448157e-05 HYPK essential 5.01323613197625e-13 0.400600833192869 0.00918809251446497 4.96099642852388 -4.17895186551833 0.00209738146638079 104.583347064274 29.6680893562234 3.52511231203825 0.000458713679235062 18.8003965484076 139.287829238461 0.134975156488521 0.892681077532422 SDHAP2 other 1 1 1 3.52511231203825 0.134975156488521 8.57659111343633e-08 55.3579800908261 16.6781646021448 3.31918897620828 0.000963689992443648 -291.959162410394 74.8076019766908 -3.90280071404194 0.000107106513488625 AMACR other 0.000623346642124553 1 1 3.31918897620828 -3.90280071404194 1.57252917283835e-16 98.7851543715659 14.3979256153748 6.86106853240568 1.87243071712139e-11 -54.0295325606382 31.0159500204823 -1.74199186305621 0.0820771362005107 MTFP1 other 1.70210557668023e-12 1 2.2027274956216e-07 6.86106853240568 -1.74199186305621 0.0939994727493637 79.1388642358777 100.265329669396 0.789294410109868 0.430285087167337 -223.852898417132 163.405629965795 -1.36992157775708 0.171278603737075 SNHG3 other 1 1 1 0.789294410109868 -1.36992157775708 3.25858831517627e-06 17.4246361471348 4.19200224796263 4.15663807327475 3.77103031940595e-05 -23.9102724156231 18.5617311407607 -1.28814883882879 0.19826159934721 ARHGDIG other 0.0207474318027273 1 0.323893794133777 4.15663807327475 -1.28814883882879 0.00666308031026276 3.23615985465652 1.28873442102885 2.51111462676147 0.0123259669287221 -5.36669698999312 3.96110070721529 -1.35484992346129 0.17603190620123 TCP10L other 1 1 1 2.51111462676147 -1.35484992346129 2.73574515456617e-33 421.531913939042 43.6013431450032 9.66786533472537 1.61699528875909e-20 -274.488405735012 86.1261495928594 -3.18705070449091 0.0015193858823113 ARFGAP3 other 3.85493849729919e-29 1 2.23404069094956e-16 9.66786533472537 -3.18705070449091 0.000168715462341309 7.1363001948471 1.72196872188498 4.14426818800474 3.95919991943255e-05 11.4062849238925 15.478627768078 0.73690543469338 0.461501082230595 BGLAP other 0.889636632925722 1 0.339501393091341 4.14426818800474 0.73690543469338 1.17932834685765e-42 229.14786670083 28.1970179770431 8.12667023468205 3.05715278557409e-15 -367.945138798597 55.2546916995754 -6.65907504830805 6.82678921945584e-11 C22orf39 other 1.74646734886149e-38 9.78415430932411e-07 3.92538417667714e-11 8.12667023468205 -6.65907504830805 0.0576959857266649 571.86779883831 774.393928895442 0.73847143875985 0.460550032550506 -4932.82296750565 2474.26790560317 -1.99364949783121 0.0466947951363431 PEG10 other 1 1 1 0.73847143875985 -1.99364949783121 8.84607072421292e-05 25.3918281366277 16.2410585459115 1.56343430847491 0.118538470309897 -180.745426151517 52.4012897490126 -3.44925529537989 0.000606210680500733 STAG3L5P other 0.483791607907205 1 1 1.56343430847491 -3.44925529537989 0.217821926830133 122.997194691908 70.6968085968966 1.73978425805924 0.0824593632378424 98.3698294758735 138.941266547223 0.707995773469073 0.479249446525669 UGT1A8 other 1 1 1 1.73978425805924 0.707995773469073 1.43782870297096e-18 504.812282015567 55.5134402293328 9.0935146503284 1.89087477477737e-18 -307.146384927516 320.238378813186 -0.959117973510267 0.337934179222137 EIF6 essential 1.64473225332849e-14 1 2.55513908315666e-14 9.0935146503284 -0.959117973510267 2.69931351331542e-19 353.962816624147 56.9620082849355 6.21401574982316 1.04599077556849e-09 -405.131614205648 108.48938033769 -3.73429743026104 0.000208628956676914 MRPL20 essential 3.14820935057978e-15 1 1.16366473781994e-05 6.21401574982316 -3.73429743026104 9.79963784731512e-22 151.798191827606 16.8042256903484 9.03333450911652 2.87734039025309e-18 -384.434281603567 104.91072585843 -3.66439445021413 0.000272158913257558 ARPIN other 1.20123960732389e-17 1 3.87980578221727e-14 9.03333450911652 -3.66439445021413 0.213047374820649 132.618725777464 75.7551112583544 1.75062413049837 0.0805712619560775 108.532504471339 148.882408054323 0.728981387994068 0.466325045217342 UGT1A10 other 1 1 1 1.75062413049837 0.728981387994068 0.86034673202468 0.473376872525526 2.41002175651231 0.196420165604886 0.844354133042252 3.65302992635941 6.6974358731069 0.545437088995193 0.585674870842323 LINC00960 other 1 1 1 0.196420165604886 0.545437088995193 0.956893643445178 -1.92095243653155 8.00037349046334 -0.240107844817667 0.810337436141455 -4.51264674343028 17.4767779804403 -0.258208163339991 0.796344274385774 SERPINB10 other 1 1 1 -0.240107844817667 -0.258208163339991 0.185686315283651 51.6049305915907 44.6068401920653 1.15688379561057 0.247825727004763 270.884265918139 156.901092856304 1.72646513154771 0.0848294194088564 HLA-DMB other 1 1 1 1.15688379561057 1.72646513154771 7.63013519566662e-18 134.719198862648 19.7683774865474 6.81488397084313 2.58664641670038e-11 -300.193800020669 86.9476742820413 -3.45257998560029 0.000599884313425212 DECR2 other 8.58313908160538e-14 1 3.0328429235812e-07 6.81488397084313 -3.45257998560029 3.01540779357676e-08 12.8131482180327 22.8412032010676 0.560966430062399 0.575051402937793 -268.727723114023 49.3475104955354 -5.44561864247105 7.82745974186894e-08 GNG10 other 0.000226607895687294 0.00104011285049954 1 0.560966430062399 -5.44561864247105 2.41277803399735e-07 3.09394290685629 0.764614705807086 4.04640779644761 5.96037013081978e-05 -3.17030568582401 1.88630311574332 -1.68069790022837 0.0933998979347261 CNTF other 0.00169618295790013 1 0.502816824235957 4.04640779644761 -1.68069790022837 0.00282556166314395 5.91528182781296 2.38718143394964 2.47793558700145 0.0135220196595845 -3.68774839279183 4.68777571535351 -0.786673385570396 0.431821406955439 CCDC169 other 1 1 1 2.47793558700145 -0.786673385570396 0.00100011898518644 -0.647802295509166 0.672260146654505 -0.963618472302645 0.335669356732659 -8.61401174261967 2.32723468593816 -3.70139367321572 0.00023646560089803 LINC00882 other 1 1 1 -0.963618472302645 -3.70139367321572 0.000341280084963082 28.2064742964614 8.33729428675165 3.38316884667042 0.000768036332093291 96.5186445875642 35.1022446163576 2.74964309668638 0.0061640859811481 ZNF702P other 1 1 1 3.38316884667042 2.74964309668638 6.38966327877437e-17 143.441220147144 19.8839443457568 7.21392182822892 1.8532023897184e-12 -223.887753103051 68.0606135232139 -3.28953474723951 0.00106908127684277 AP5Z1 other 6.99987612189732e-13 1 2.24070700940852e-08 7.21392182822892 -3.28953474723951 0.179631260348647 -2.45242006507617 2.2340326697624 -1.09775479037063 0.272804469864972 -13.5816025061299 9.2475902864371 -1.46866395303533 0.142510575068132 SOX2-OT other 1 1 1 -1.09775479037063 -1.46866395303533 5.24586797506893e-06 8.63696397930209 2.86181726051832 3.01799982076346 0.00267508662165881 -10.8935436985675 5.32818606160101 -2.04451263011903 0.0414292779847149 STRC other 0.0326712657487293 1 1 3.01799982076346 -2.04451263011903 5.27676549733741e-11 70.8359502757879 24.2359038193981 2.92276907862176 0.00361364590891773 -284.0495981879 57.3800190833728 -4.95032247680464 9.89817262807492e-07 EIF4EBP3 other 4.6150591039713e-07 0.0125746385067064 1 2.92276907862176 -4.95032247680464 0.679555368547206 19.1199736330778 21.7891188435995 0.877501002694021 0.380640264553184 20.6050100829572 64.6233685933114 0.318847663491962 0.749976529739627 ABCC13 other 1 1 1 0.877501002694021 0.318847663491962 0.000558859510973214 14.540457181653 3.7985103755782 3.82793667621343 0.000144180924161538 14.4797340409139 15.2428109264374 0.949938571749913 0.342563746647937 ARHGEF26-AS1 other 1 1 1 3.82793667621343 0.949938571749913 0.215031254981796 123.659639359476 70.7677295126343 1.7474015375525 0.0811288629777389 98.5577936174936 139.08064825416 0.708637721024899 0.478851205073614 UGT1A3 other 1 1 1 1.7474015375525 0.708637721024899 0.705659967067332 3.21868630478583 4.27469434976651 0.752962911830559 0.45181034380658 -2.16191797503778 16.1677664703069 -0.133717788354271 0.893677077358376 PSG4 other 1 1 1 0.752962911830559 -0.133717788354271 7.38664595359207e-14 120.695770788721 15.4136700982918 7.83043687966933 2.58157888649416e-14 6.27748648842208 47.4951511027293 0.132171102579382 0.894898098527885 MRPL33 essential 7.30391551891184e-10 1 3.25717808108968e-10 7.83043687966933 0.132171102579382 5.70185080629642e-13 265.832674620156 42.792553285217 6.21212463879759 1.04086968074297e-09 -48.4980192104285 83.2168372354775 -0.582790944976608 0.560275974666121 MICAL3 other 5.4321532631586e-09 1 1.15827978073078e-05 6.21212463879759 -0.582790944976608 1.46935035381467e-29 195.520772829346 16.8224978576955 11.6225767708987 4.85475099750621e-28 -66.840876937729 61.3172001537792 -1.09008364325339 0.276159805859909 PPAN-P2RY11 other 2.00125518189558e-25 1 7.07337220336654e-24 11.6225767708987 -1.09008364325339 0.000380760302602012 15.2295188789399 43.0117968528996 0.354077718050814 0.72342092990777 -360.278913566744 100.513318303928 -3.58438980670549 0.000368943159261802 PCDHAC2 other 1 1 1 0.354077718050814 -3.58438980670549 0.000111124324539395 76.8355221231496 18.2554154040572 4.20891666513779 3.00010998240186e-05 97.1989639649631 65.5076108622433 1.48378123832609 0.13844398134802 STON1 other 0.600071352512735 1 0.260409546472482 4.20891666513779 1.48378123832609 5.44293545905175e-07 54.0951918778755 22.5423872055468 2.39970999453708 0.0167534900440996 -354.974522430182 83.4198943319431 -4.25527417977387 2.47067407628505e-05 KCTD7 other 0.00371480345080282 0.290773632037988 1 2.39970999453708 -4.25527417977387 2.94567272105344e-10 92.8417385938582 13.7207529949999 6.76651920107386 3.57136174618133e-11 -35.9938938702545 141.898657046345 -0.253659158017956 0.799859342399911 EFNA4 other 2.48290753657594e-06 1 4.16706488544438e-07 6.76651920107386 -0.253659158017956 8.43061484931765e-22 4.53033907341651 5.79355873149323 0.781961361466834 0.434608156609719 -83.1524451199418 10.0619678246154 -8.26403409048071 1.27984849162512e-15 MRPS31P5 other 1.03468936045676e-17 1.93141935871147e-11 1 0.781961361466834 -8.26403409048071 0.0347422829650182 5.58832611970271 7.10663471480507 0.786353364703085 0.432005431183558 -31.9044983328417 15.9553256184633 -1.99961436674926 0.0460424087175854 TICAM2 other 1 1 1 0.786353364703085 -1.99961436674926 0.0461719253439755 7.65631781644595 6.75891379180871 1.13277340890556 0.257805699325217 34.9693040276456 14.1906484443011 2.46424990125728 0.014036433714339 PALM2 other 1 1 1 1.13277340890556 2.46424990125728 0.0569765809363813 27.195879651339 12.0138557078246 2.26370952945825 0.0239909197475453 9.64808147694248 24.2174260208759 0.398394175690911 0.690498295095072 C4orf48 other 1 1 1 2.26370952945825 0.398394175690911 4.98170499488508e-23 19.2818460340426 7.22368196446726 2.66925456143952 0.00783731562660735 -103.017847686228 13.2851855025511 -7.75434017586329 4.64436779976165e-14 NAT6 other 6.24406904058896e-19 6.91453478028515e-10 1 2.66925456143952 -7.75434017586329 8.78188372469063e-09 20.0903302440347 3.24274059399757 6.19547868898999 1.15595429048886e-09 21.3385399403759 9.4925680881427 2.24792066195766 0.0249854318937548 MNX1-AS1 other 6.8156199587324e-05 1 1.28380283501692e-05 6.19547868898999 2.24792066195766 0.100248038485285 -1.12297902003954 3.38720197773989 -0.331535889332719 0.740372796916505 -13.3470122189566 6.48425860868437 -2.05837136123487 0.0400502825260579 AMY2A other 1 1 1 -0.331535889332719 -2.05837136123487 0.0209403844426582 6.71431720142318 2.5196574498385 2.66477381750981 0.00794808128475878 -10.0873479433652 19.5969772758526 -0.514739992876084 0.606957722910323 TNFRSF6B other 1 1 1 2.66477381750981 -0.514739992876084 0.00787946458001202 20.3485543352013 6.7306069373864 3.02328668491567 0.00261943597355062 -2.11420238455953 22.9770299368939 -0.0920137367782588 0.926721312872611 UPK3B other 1 1 1 3.02328668491567 -0.0920137367782588 6.30601377657568e-22 174.9274128319 17.4451003917728 10.0273090382671 8.26268100734354e-22 -27.3567518712284 54.4855074368604 -0.502092265597972 0.615808044789421 IL10RB other 7.75954995207637e-18 1 1.15429653672589e-17 10.0273090382671 -0.502092265597972 0.00131141589514964 -1091.71633466193 920.563522971139 -1.18592178314691 0.236185581318812 -11580.0254097959 3158.59102546077 -3.66619968095004 0.000271044602940363 CFB other 1 1 1 -1.18592178314691 -3.66619968095004 1.47878323050474e-11 40.7707297744329 6.64700195109716 6.13370209221967 1.6491119084272e-09 -57.7665254797626 21.6801298717083 -2.66449167147959 0.00793845636169168 WDR92 other 1.32868673260851e-07 1 1.81831079023183e-05 6.13370209221967 -2.66449167147959 5.83108412635268e-36 2184.42213474903 163.918741476981 13.3262500374662 5.1956019236005e-35 -513.691170884433 638.077336900616 -0.805060987402603 0.421156723106193 NME2 other 8.37285369702982e-32 1 7.76274883405151e-31 13.3262500374662 -0.805060987402603 8.32278355529554e-07 -34.0325495529034 9.19491650085196 -3.7012353021096 0.000236609574627053 -136.164170529424 31.8310236321137 -4.27771887273051 2.23417021410768e-05 DUBR other 0.0056012333327139 0.263855502286118 1 -3.7012353021096 -4.27771887273051 5.59295607673728e-08 -12.0534127405891 16.3007081236147 -0.739441050608557 0.459982116784713 -150.352786662927 27.5859278920007 -5.45034364084326 7.86688979258878e-08 PLA2G4B other 0.000412983876706281 0.00104527364674127 1 -0.739441050608557 -5.45034364084326 0.0605661109456484 2.29353616434849 1.44617772197281 1.58592967482569 0.113341729290472 16.8865052650259 9.0746816207766 1.86083721398711 0.0633114592759085 LEFTY1 other 1 1 1 1.58592967482569 1.86083721398711 1.16389484539301e-07 7.48894036605163 6.49219778462421 1.15352930001425 0.249202561067797 -72.3423701287399 14.6213383639669 -4.94772559993699 1.0040950998629e-06 CFAP57 other 0.000837887899198427 0.0127489954829592 1 1.15352930001425 -4.94772559993699 2.52612256856666e-44 217.364553553383 16.6406004816611 13.0623022764672 4.20529581507047e-34 -142.217499988064 37.5894082262974 -3.78344610087714 0.000171869867497259 TTC4 essential 3.76215434136633e-40 1 6.26799341236253e-30 13.0623022764672 -3.78344610087714 0.0438611999037942 -11.4273644998591 15.4620203501854 -0.739060241873373 0.460203883909146 -99.0689726194548 39.6328465335675 -2.49966836309744 0.0127380132939894 RPLP0P2 other 1 1 1 -0.739060241873373 -2.49966836309744 1.96374101533629e-05 -5.52425099939689 16.3314434449248 -0.338258587982534 0.735300042385722 -128.792200872805 29.2525576941624 -4.40276717746654 1.28927388576144e-05 TMEM35B other 0.116332017748522 0.1546741880748 1 -0.338258587982534 -4.40276717746654 4.43302096095791e-07 256.671026295326 48.9197393405903 5.2467782894002 2.21993776976969e-07 -7.47418120110271 184.044392079911 -0.0406107522029656 0.967621084649423 HLA-L other 0.00305213493161952 1 0.00222393365775527 5.2467782894002 -0.0406107522029656 0.288242924023395 0.980320635672991 1.71557421099224 0.571424208519665 0.567947693747378 5.6648815988374 3.62126806037847 1.56433644358417 0.118319014387281 OSTCP1 other 1 1 1 0.571424208519665 1.56433644358417 4.50032202268277e-27 5.8139063883766 11.0884178028799 0.524322449941109 0.600277278596059 -185.126175750813 18.6729746692641 -9.91412343398784 2.43534623038502e-21 JMJD7 other 5.97777774272952e-23 3.76601941066739e-17 1 0.524322449941109 -9.91412343398784 1.58868237472084e-05 19.0675546158138 5.8155712804135 3.27870706013565 0.00110948009888223 -18.2277581185059 12.0680287151129 -1.51041719810288 0.131517615436729 APOBEC3D other 0.0949078850658232 1 1 3.27870706013565 -1.51041719810288 0.532932253621032 0.55701926502977 1.65203087118982 0.337172431062742 0.736116726846178 -4.55697962545912 5.07635575505728 -0.897687208174736 0.36974871666669 WDR86-AS1 other 1 1 1 0.337172431062742 -0.897687208174736 0.282173139062559 0.837382864846914 1.8645132977309 0.449116059330873 0.653528123332433 -5.67404813446104 4.19674019549783 -1.35201319837431 0.176937073423176 TUBA4B other 1 1 1 0.449116059330873 -1.35201319837431 4.67396653362627e-27 286.21021292553 24.8877823924988 11.5000287455018 1.63355680094754e-27 33.4129483167486 75.4994563823205 0.442558793371297 0.658263095297603 MRPS6 essential 6.20562536669559e-23 1 2.37323132041658e-23 11.5000287455018 0.442558793371297 0.0551793429582612 19.4890818411162 29.8724649933151 0.652409563304452 0.514414099803243 -195.412276996758 92.0479827076179 -2.12293926763683 0.0342123772907776 ZNF512 other 1 1 1 0.652409563304452 -2.12293926763683 0.119417630171816 52.0220992230051 27.6323265171497 1.88265360829166 0.0603230797697599 -22.6729800346325 102.059835701297 -0.222153797121431 0.82428415030314 GSTA1 other 1 1 1 1.88265360829166 -0.222153797121431 7.07227217207721e-24 90.641749297376 43.1533670724902 2.10045601181279 0.0361697198583764 -656.008118583189 78.8938728369433 -8.31507054976267 8.07060439044515e-16 ACY1 other 8.98107843132085e-20 1.21914549922064e-11 1 2.10045601181279 -8.31507054976267 8.84346965808292e-36 164.915407311503 13.0011711995701 12.6846577727518 2.30542956493515e-32 -215.392556368022 70.1222157368001 -3.07167356457313 0.00223856348020069 NFS1 essential 1.26877259184516e-31 1 3.41779933001636e-28 12.6846577727518 -3.07167356457313 3.14265087404206e-06 16.2752126136796 4.79663493091 3.39304801138826 0.000741326055362705 -21.2893342700244 10.0010275411191 -2.12871469281467 0.033724873738438 FAM86DP other 0.0200375419728922 1 1 3.39304801138826 -2.12871469281467 1.60925214583583e-18 1323.97018667856 180.860319501328 7.32040167975509 8.90206503212991e-13 -359.233134255439 299.219191324098 -1.20056849517495 0.230439228531635 DDOST essential 1.83921427747577e-14 1 1.082491107907e-08 7.32040167975509 -1.20056849517495 1.33572771063928e-12 13.5381766357053 2.71460760983456 4.98715784434508 8.32181445092651e-07 -30.836694206513 8.08240383686688 -3.81528748487613 0.0001520855834301 LINC01011 other 1.25638548462731e-08 1 0.0080513554812714 4.98715784434508 -3.81528748487613 0.263703561550257 4.0780976797437 3.34266826753405 1.22001268248859 0.223030624131257 -8.07760616482529 12.3461256140242 -0.654262431580135 0.513241173711818 GSTA2 other 1 1 1 1.22001268248859 -0.654262431580135 6.11865945500959e-08 12.0479490353812 21.7003589532601 0.555195840830607 0.57898893218997 -249.750595983211 46.8827619007756 -5.32713060957867 1.46307149687597e-07 DNAJC25-GNG10 other 0.000449966216321405 0.00192291486834408 1 0.555195840830607 -5.32713060957867 0.329573056440662 119.831086974876 80.407217455428 1.49030262166829 0.13672106698077 82.4186599735067 158.025246889087 0.521553749138287 0.602192174675515 UGT1A7 other 1 1 1 1.49030262166829 0.521553749138287 2.81656357229128e-24 54.1593481950904 32.4386138477296 1.66959502182554 0.0955748045257994 -533.864924023949 61.2262621348241 -8.71954134401255 3.39395745381035e-17 FLNB-AS1 other 3.60041321445995e-20 5.16933659789854e-13 1 1.66959502182554 -8.71954134401255 1.49041874503776e-19 100.585268219872 13.3638627408063 7.52666127830968 2.17833377660328e-13 -203.726407389817 48.7106405622632 -4.18237996951422 3.36320098972685e-05 P2RY11 other 1.74900639730182e-15 0.391981075352664 2.692202714504e-09 7.52666127830968 -4.18237996951422 2.16886329094624e-07 252.796417065118 73.3875317591111 3.44467801281153 0.000618382057229458 -522.819701740615 170.188278338339 -3.07200770138374 0.00223869978262459 TMEM141 other 0.00153056682442076 1 1 3.44467801281153 -3.07200770138374 3.49902879802229e-06 5.62097284164278 2.47244841448187 2.27344393060703 0.0233905372667156 -29.0994777452349 7.8661855774477 -3.69931238701804 0.000238279602645222 TMEM225B other 0.0221908406370574 1 1 2.27344393060703 -3.69931238701804 0.0123595823777884 -77.7768642109249 58.8867625048559 -1.32078689509397 0.187126750479666 -349.336314020401 117.459702550798 -2.97409499968147 0.00306864976596245 IFITM10 other 1 1 1 -1.32078689509397 -2.97409499968147 2.70290761524193e-06 190.723717293723 51.5978155949862 3.69635255086759 0.000240961290967979 -1039.13465556794 341.445129972497 -3.04334302747746 0.00245311904915711 DBNDD2 other 0.0173472610746227 1 1 3.69635255086759 -3.04334302747746 0.00226846031443908 2.97865627497696 9.47985991490394 0.314208891451446 0.753482629147599 57.8920773188849 17.9542616084035 3.22441983867432 0.00133787344341205 FAM3D-AS1 other 1 1 1 0.314208891451446 3.22441983867432 0.000333668723549754 90.8851001409611 31.0988438663107 2.92245912843779 0.00361745669188533 352.511889050292 125.370437687566 2.81176245016215 0.00510520273481141 ETV5 other 1 1 1 2.92245912843779 2.81176245016215 0.996326798863735 -0.241086697539812 3.03276977169547 -0.0794939001931005 0.936670248276272 -0.833010610533329 21.2827183085907 -0.0391402356811295 0.968793546548739 CFHR1 other 1 1 1 -0.0794939001931005 -0.0391402356811295 9.49612764793657e-07 116.708604112969 33.1243138535097 3.52335159692986 0.000463159194046364 -599.460424190782 178.657003012628 -3.35537042535304 0.00084970489511104 RBM12 other 0.00635575823476395 1 1 3.52335159692986 -3.35537042535304 0.212847790356732 127.050959151673 72.4251397319443 1.75423837112233 0.0799496119957097 99.7780075983614 142.337975984076 0.700993581709521 0.483605107913356 UGT1A4 other 1 1 1 1.75423837112233 0.700993581709521 0.477871998319631 2.41671879785962 2.0245052701372 1.19373302381961 0.23310753822852 3.81058798305566 9.10004480421838 0.418743870501521 0.675570136515887 LILRA6 other 1 1 1 1.19373302381961 0.418743870501521 0.297774069040004 -9.12623690250254 16.7763938955135 -0.543992765032966 0.586675646936995 33.5041280103373 34.3914842384917 0.974198373585713 0.330403307846869 SCARF2 other 1 1 1 -0.543992765032966 0.974198373585713 0.105504326436335 -13.6870713429495 29.2775993927824 -0.467492951157862 0.640334440935098 -124.666462386994 60.7546349524836 -2.05196628182353 0.0406510233798257 APOBEC3C other 1 1 1 -0.467492951157862 -2.05196628182353 0.572429719071596 0.703832454544061 3.2359609097895 0.217503385907664 0.827897175406697 -5.06751463117004 6.20442215072934 -0.816758516435627 0.414422008209776 CCDC13 other 1 1 1 0.217503385907664 -0.816758516435627 0.45875421678233 1.54479264271522 2.36503882132438 0.653178556219288 0.513916622812994 -7.60563077291629 7.98240890642263 -0.952798943536558 0.341114325487312 ASPRV1 other 1 1 1 0.653178556219288 -0.952798943536558 1.40154428477122e-44 584.651860818826 37.9213346008981 15.4174916830322 1.45625262393705e-44 -397.988747831542 290.343996524238 -1.37074901701409 0.171034512275341 UBE2V1 other 2.08984268302237e-40 1 2.21597961784501e-40 15.4174916830322 -1.37074901701409 1.9062273379489e-06 20.3052948293139 5.79313651470711 3.50506064853894 0.000494500943533897 -51.4620696062331 19.9670261090854 -2.57735274772926 0.0102206307912028 CTAGE8 other 0.0124171648793991 1 1 3.50506064853894 -2.57735274772926 0.817441241444446 -1.38853319317374 2.81082165565791 -0.493995480068527 0.621509505623474 -6.81424453367398 13.4137355506215 -0.508004985483576 0.611656522503684 PTCHD4 other 1 1 1 -0.493995480068527 -0.508004985483576 0.000293195164891091 -3970.98207329752 1392.96300863073 -2.850744814251 0.00454012568351131 -19073.1990352047 5301.78311200885 -3.59750646758876 0.000352906094492907 C4A other 1 1 1 -2.850744814251 -3.59750646758876 0.224416045744428 80.3667530269519 202.272664295069 0.397318902714977 0.691287014480397 758.450151564542 445.123006751696 1.70391136845378 0.0889645466523476 HBB other 1 1 1 0.397318902714977 1.70391136845378 2.6046433760227e-07 7.65336319757333 1.44125241115045 5.31021709893563 1.59820193861014e-07 3.34331895010691 3.10348872198851 1.07727762192889 0.281833736058452 CRYBB2 other 0.00182585500659191 1 0.00161274557625149 5.31021709893563 1.07727762192889 1.19009781415809e-29 120.844055084035 43.2265408111622 2.79559855626547 0.0053675621037807 -775.914978368534 85.6832576303741 -9.05561949705187 2.56880526133596e-18 N4BP2L2 other 1.62365044785588e-25 3.93309773563148e-14 1 2.79559855626547 -9.05561949705187 1.08633924079562e-09 31.1054096427896 21.0207778260741 1.47974589238114 0.139527468206333 -228.17982236548 43.0586653302737 -5.29927763936175 1.6999888995032e-07 MIR4712 other 8.87539159730025e-06 0.00222647546167934 1 1.47974589238114 -5.29927763936175 4.36555326481554e-05 6.46460688801274 2.1044761119867 3.07183666813396 0.00223528819546307 -26.2145362918557 9.91280114592805 -2.6445134837214 0.00842022164366624 LIFR-AS1 other 0.249273091420967 1 1 3.07183666813396 -2.6445134837214 2.43112652101615e-25 76.3971145821411 11.4848274282346 6.65200370310525 7.25381530195280e-11 -191.711722563335 30.5624576065177 -6.27278489942023 7.39940882626041e-10 LINC00847 other 3.15535911162686e-21 1.03983892235437e-05 8.38686125211783e-07 6.65200370310525 -6.27278489942023 4.70717658011257e-05 -93.1655057054347 23.9601407177475 -3.88835386248071 0.00011359680135671 -203.261167737398 57.8201979751258 -3.51540075709945 0.000476268419298297 IGFBP7-AS1 other 0.267414701516195 1 0.933424916748084 -3.88835386248071 -3.51540075709945 0.170059856949658 31.5312697627925 23.3286277439875 1.35161270987827 0.17705790591274 -67.9167018327198 77.4361763205115 -0.877066831807523 0.38083536839082 A2M-AS1 other 1 1 1 1.35161270987827 -0.877066831807523 8.68799031754849e-05 10.8365784422269 4.04650406237478 2.67801002425468 0.00763373583849236 -21.3868239179297 9.3087808166464 -2.29748925656137 0.0219759907433992 SMARCA5-AS1 other 0.475580589982604 1 1 2.67801002425468 -2.29748925656137 9.64363898002519e-10 12.4665860111118 1.97322591629949 6.31787060373255 5.59366894970645e-10 -37.5557390273174 22.6050096433361 -1.66139009095219 0.0972220557541353 RNF139-AS1 other 7.89621159684463e-06 1 6.28784326636502e-06 6.31787060373255 -1.66139009095219 0.191585548700153 -1.76247357105085 0.981188158702799 -1.79626461593357 0.0730207363431506 2.68748552332678 10.8525970185797 0.247635245160748 0.804512362518977 LINC00861 other 1 1 1 -1.79626461593357 0.247635245160748 1.29999049384734e-18 8.52315662214823 4.25754008001865 2.00189697852731 0.0457927415838966 -71.1788737136398 9.42474091361539 -7.55234275043165 1.82268437905414e-13 SCAMP1-AS1 other 1.48913911070213e-14 2.69866649162755e-09 1 2.00189697852731 -7.55234275043165 9.55831732263961e-12 9.33590578319906 3.38181317309971 2.76062139016447 0.00596676645997097 -47.1043714147036 8.56087525425132 -5.50228452298865 5.81629041174973e-08 BDNF-AS other 8.66939381163412e-08 0.000775776815119179 1 2.76062139016447 -5.50228452298865 1.14721564640626e-22 11.0413734323769 1.07179201457109 10.3017873638436 8.35553037216114e-23 -1.84042674535287 5.31673881261538 -0.346157073013624 0.72936230406457 DDX11-AS1 other 1.43023374637469e-18 1 1.17821333777844e-18 10.3017873638436 -0.346157073013624 1.10133245699188e-10 26.475773804602 8.38512213074159 3.15747026600082 0.00167967845725452 -205.480499021369 38.6848549048171 -5.31165231269309 1.58628069768277e-07 ZNF585B other 9.47916845732912e-07 0.00208088301922026 1 3.15747026600082 -5.31165231269309 0.279219565488301 6.52027668002159 4.09319220382273 1.59295639084139 0.111748690049018 3.8750195489816 9.51974842516797 0.407050625280913 0.684130330065275 LINC02202 other 1 1 1 1.59295639084139 0.407050625280913 0.096517510907807 101.423960759509 48.1743550331321 2.10535171025651 0.0357306392638373 -9.40784937984159 216.07808418554 -0.0435391188111579 0.965288179813143 CEBPA other 1 1 1 2.10535171025651 -0.0435391188111579 6.83339841167716e-18 5.84271683643822 3.77515578975513 1.54767568858852 0.122281925161461 -48.3976566424144 6.62506339707226 -7.30523675649688 9.90955476577702e-13 RAD51-AS1 other 7.69372327170731e-14 1.45620907283093e-08 1 1.54767568858852 -7.30523675649688 0.999002578026326 0.0193465607242045 3.12970046597397 0.0061816013815187 0.995070093267461 -0.265952876963836 6.96555438842688 -0.0381811500037543 0.969557257086823 MEF2C-AS2 other 1 1 1 0.0061816013815187 -0.0381811500037543 2.84110718941201e-24 56.6817655287653 18.3187360006152 3.09419632047002 0.00207451890525066 -361.602631013382 42.3852282077434 -8.53133618252692 1.43094905476055e-16 LINC01184 other 3.63121909878749e-20 2.17117900078819e-12 1 3.09419632047002 -8.53133618252692 3.60831686659963e-44 72.0983179237201 5.63847151287667 12.7868550473418 9.88722731545062e-33 -24.7562530792089 13.2747032152023 -1.86491951479999 0.0627579210501848 RAB30-AS1 other 5.37170131930686e-40 1 1.46736340588603e-28 12.7868550473418 -1.86491951479999 0.000762110440813828 -5.34274682407995 5.81209968040618 -0.919245559757257 0.358373808945057 -75.800549118879 19.9079447921769 -3.80755270873896 0.000156288057148165 NUDT16P1 other 1 1 1 -0.919245559757257 -3.80755270873896 1.05856213322956e-76 75.8954554362737 3.58332116114666 21.1801990452866 1.00896190592269e-71 -30.0615116151005 17.716763476498 -1.69678348164315 0.0903538060231675 KCTD21-AS1 other 1.64362942426554e-72 1 1.56711963227912e-67 21.1801990452866 -1.69678348164315 0.0389352008058244 3.46498455496896 2.3999127377008 1.44379605997197 0.149373042169206 -6.75750461671627 4.9034616214838 -1.37810900509739 0.168737231517165 LINC01550 other 1 1 1 1.44379605997197 -1.37810900509739 0.991096931716554 0.365761380003443 2.83223047338888 0.129142519805528 0.897294336934878 1.2244157254774 31.5227358726351 0.0388423051357136 0.969030881179799 CASC8 other 1 1 1 0.129142519805528 0.0388423051357136 1.16509647081705e-46 44.1065973841021 2.76156864393124 15.9715737941295 3.40093687703223e-47 -63.5221863704442 34.4993662711596 -1.8412566153004 0.0661405295132159 UBR5-AS1 other 1.74659611940185e-42 1 5.19425089229133e-43 15.9715737941295 -1.8412566153004 2.01381546738556e-09 37.8469487692704 7.7050538368874 4.91196422120775 1.19571033313982e-06 -29.4195599985005 16.2402490593995 -1.81152147919019 0.0706135493067467 SBF2-AS1 other 1.62494770063341e-05 1 0.0114561007018126 4.91196422120775 -1.81152147919019 1.01810972452606e-11 5.73732183208453 1.22272274582594 4.69225084073251 3.42582567004728e-06 -3.34954573437518 2.46161231453458 -1.3607121294437 0.174170226269875 EXTL3-AS1 other 9.22407410420608e-08 1 0.0318738820341199 4.69225084073251 -1.3607121294437 9.12267629905415e-49 16.1074058695861 0.974421097385486 16.5302310395419 8.64222061292557e-50 5.16713536430272 9.05472666098842 0.570656139910321 0.568475068769808 LACTB2-AS1 other 1.37506099855643e-44 1 1.32416104231246e-45 16.5302310395419 0.570656139910321 1.83191061520259e-18 9.38496637305262 1.04526199465811 8.97857802255816 4.65853311183892e-18 -2.21969471584649 4.58025172206965 -0.484622865846222 0.62814223722926 CACNA1C-AS1 other 2.09130915831528e-14 1 6.26619288873453e-14 8.97857802255816 -0.484622865846222 0.0201438005887223 443.840428278344 245.243927439121 1.80979171599885 0.0708839183130306 -1145.80812686356 786.82032454564 -1.45625130810547 0.145904320791289 H2AFJ other 1 1 1 1.80979171599885 -1.45625130810547 1.1704754674066e-10 2.51393018700617 1.15725477043188 2.17232216382913 0.0302616785147226 -13.8919149765694 2.67754047824605 -5.18831184418524 2.99813168118653e-07 RGMB-AS1 other 1.00555547404901e-06 0.00388887660366705 1 2.17232216382913 -5.18831184418524 0.149247094541095 -28.2345773004136 19.40580304405 -1.45495536754252 0.146257325155389 28.1584512853807 43.2656088985158 0.650827574192458 0.515432087210922 STARD4-AS1 other 1 1 1 -1.45495536754252 0.650827574192458 1.07568098862108e-16 32.636577385904 4.86405131908994 6.70975186010378 4.96015539877634e-11 -42.6969050567785 11.0771400213361 -3.85450621501022 0.000129999271229604 UBAP1L other 1.17141659660836e-12 1 5.75973244905909e-07 6.70975186010378 -3.85450621501022 0.0325149411438262 -5.69618524674394 7.87801283185762 -0.72304848548981 0.469965483340596 -53.4829959661167 20.3671692020983 -2.62594155502998 0.00888793046451855 SOCS2-AS1 other 1 1 1 -0.72304848548981 -2.62594155502998 1.32115460022696e-12 254.67761148799 36.6722998278143 6.94468611687203 1.10831154245193e-11 -69.1331789774248 87.776536763471 -0.787604313482042 0.431278290370345 PGAM5 other 1.2428101324335e-08 1 1.31334917780554e-07 6.94468611687203 -0.787604313482042 1.36438272751956e-20 14.2494442417906 1.43116663872236 9.95652347969171 1.56268581291983e-21 16.1310803632648 17.2063243290481 0.937508793556333 0.348921509292206 BAALC-AS1 other 1.63384831620467e-16 1 2.17838402321024e-17 9.95652347969171 0.937508793556333 0.000867619548472238 25.1175739919152 7.36948921291945 3.40831952747574 0.00070241829197482 6.18198141997257 15.1486265629149 0.408088574518469 0.683370403965041 MIR210HG other 1 1 1 3.40831952747574 0.408088574518469 0.497797305135718 0.553608374822833 1.4489361711247 0.382079201179104 0.7025518295859 -4.84495138684222 5.1176694536338 -0.946710496005571 0.34420664414648 LINC01252 other 1 1 1 0.382079201179104 -0.946710496005571 6.46083162982757e-21 7.56868857050326 1.62517543622226 4.65715171532298 4.03952820139156e-06 -22.6331670930998 3.13312719450656 -7.22382644815169 1.72672526083891e-12 UBL7-AS1 other 7.79951594352784e-17 2.53051586975942e-08 0.0374019916166845 4.65715171532298 -7.22382644815169 1.02115547400155e-08 35.9084317757033 10.9629878115198 3.27542385279047 0.00112270824649559 -81.4752429329793 23.3578127048955 -3.48813666597743 0.000526063110906626 ZBED5-AS1 other 7.88944719213594e-05 1 1 3.27542385279047 -3.48813666597743 2.41842501408222e-23 80.516734051636 11.0187848454306 7.30722445179838 9.93107778916456e-13 -220.813411582042 40.780300592299 -5.41470779702249 9.27250057435401e-08 ZCCHC3 other 3.04600630523656e-19 0.00122860632610191 1.20642732982771e-08 7.30722445179838 -5.41470779702249 1.79009333599714e-15 26.103391821433 3.80154227225407 6.86652678097286 1.82717554004787e-11 -23.2066715073569 9.54238167418326 -2.43195800584482 0.0153438803096756 DNAJC3-AS1 other 1.8765548441258e-11 1 2.15076832819034e-07 6.86652678097286 -2.43195800584482 6.42135142286836e-23 7.80714072158887 3.77965952800026 2.06556719295811 0.0393432624541388 -74.8333482770054 8.54150271170012 -8.7611455270627 2.46791084379866e-17 CKMT2-AS1 other 8.03567917057747e-19 3.76208329028668e-13 1 2.06556719295811 -8.7611455270627 8.6784119188485e-05 109.956204230933 41.1675858906075 2.67094127217257 0.00780039241517997 -127.781581282259 75.281990523664 -1.69737251092068 0.0902234560532569 TWF2 other 0.475143052556955 1 1 2.67094127217257 -1.69737251092068 2.36335023784326e-05 35.8408185129808 7.98831709484454 4.48665445893624 8.85575192564251e-06 -4.55217292337435 20.4199825207524 -0.222927366306415 0.823676805925522 MARS2 essential 0.138445056932858 1 0.0801711221828417 4.48665445893624 -0.222927366306415 3.18727572204804e-21 2.07952473838764 1.38642024862101 1.49992380770262 0.134211072441342 -21.3531017470465 2.68281355693684 -7.95921941419843 1.00446981509223e-14 STX18-AS1 other 3.86775908870529e-17 1.50459533602665e-10 1 1.49992380770262 -7.95921941419843 0.546651698281942 -10.7048465134485 12.9856273622796 -0.82436113518425 0.410100390253547 -34.9894562381861 38.1006930263566 -0.918341727117186 0.358852272314361 PCED1B-AS1 other 1 1 1 -0.82436113518425 -0.918341727117186 0.354866319035454 1.01048717336807 0.781222200727121 1.2934696075298 0.196404794168191 1.984305019074 2.17543795906682 0.91214047764671 0.362104068422273 NR2F2-AS1 other 1 1 1 1.2934696075298 0.91214047764671 2.36137345561391e-07 15.0554482917611 4.24835807387041 3.54382752818314 0.00042828727858147 -24.4734985241511 9.47999436286017 -2.58159420643023 0.0100950022469875 TMEM161B-AS1 other 0.00166099008867883 1 1 3.54382752818314 -2.58159420643023 6.36423440650491e-08 3.28345980948173 0.830554337599114 3.9533353338124 8.72837131204635e-05 -4.18141149341336 1.80342136569989 -2.3185992874109 0.0207878842195361 SEC24B-AS1 other 0.00046749107534976 1 0.725185017362883 3.9533353338124 -2.3185992874109 1.98567529068316e-05 -7.98037336049162 2.9190417149524 -2.73390178688205 0.00646350225516566 -24.8662959593811 5.42528834774522 -4.58340540917345 5.68401615168157e-06 LINC00926 other 0.117551977208443 0.0696235138419475 1 -2.73390178688205 -4.58340540917345 6.70371482428421e-15 22.5375188258571 13.447469192153 1.6759673142816 0.0943191791911116 -218.632083690163 30.0819709291846 -7.26787763357796 1.2756072712249e-12 NRAV other 6.89812255418845e-11 1.87195367052254e-08 1 1.6759673142816 -7.26787763357796 0.116356873683162 5.16411028458384 7.66694827777781 0.673554861397944 0.500878333350899 -30.4661650227018 18.8811636099462 -1.6135745472092 0.107195395291397 FAM13A-AS1 other 1 1 1 0.673554861397944 -1.6135745472092 1.10441701338025e-19 46.8195175868884 9.20607498557659 5.08571977311088 5.08359301156278e-07 -128.442376904757 22.6475489829503 -5.67135883010794 2.32730393068747e-08 UBA6-AS1 other 1.29989882474856e-15 0.000314418761035877 0.004983446229235 5.08571977311088 -5.67135883010794 6.50549910732213e-15 141.106741099469 30.751333225733 4.58863815964214 5.53996852873168e-06 -493.46025714303 98.583834931358 -5.00548855181599 7.5291361875328e-07 BCKDHA other 6.69676078107741e-11 0.00961922439319191 0.0508569110937568 4.58863815964214 -5.00548855181599 0.531987236947247 13.1720805979021 27.0820403687488 0.486376964901874 0.626895794602098 -45.4798071526645 60.9357011461263 -0.746357329073839 0.45577399938305 ADH1C other 1 1 1 0.486376964901874 -0.746357329073839 1.25963516167831e-29 150.123647816984 12.9538715497252 11.589094985288 6.49199014588267e-28 -27.605458543857 49.2370830561878 -0.560663971753862 0.575257044613477 TRIM39-RPP21 other 1.71776446998071e-25 1 9.45428524944893e-24 11.589094985288 -0.560663971753862 8.69809426558307e-09 20.4091691814813 3.80247493437057 5.36733825567209 1.20856395282999e-07 -11.6125613484615 10.0368694730542 -1.15699037231055 0.247810582424111 TRIM52-AS1 other 6.75233057837214e-05 1 0.00122790097607527 5.36733825567209 -1.15699037231055 0.60657412722108 -0.650051560954934 2.64685830915929 -0.245593637825444 0.806089610966843 -5.83415524791637 5.90697980904907 -0.987671438960883 0.323753476727021 MEF2C-AS1 other 1 1 1 -0.245593637825444 -0.987671438960883 0.156553454831601 -4.48133272293799 3.91641570680503 -1.14424337415239 0.253029662955866 -16.1502410371144 8.66510476812922 -1.8638252472741 0.0628887389880378 APELA other 1 1 1 -1.14424337415239 -1.8638252472741 1.35209865244229e-22 166.079415954966 23.5737830690561 7.04508968579456 5.68399729930208e-12 -202.897537678469 48.6374985129848 -4.17162773336917 3.52461864786236e-05 CDK11B other 1.68295719269491e-18 0.410300856797657 6.78612437563675e-08 7.04508968579456 -4.17162773336917 1.6408772339275e-21 -53.4733699658525 29.6704520150362 -1.80224318587238 0.0720615865436889 -549.372520355113 56.8110701267677 -9.67016673210429 1.625320537246e-20 LINC00504 other 2.00104978677458e-17 2.50705692870195e-16 1 -1.80224318587238 -9.67016673210429 0.000302359787562717 12.9121735894158 40.452478630506 0.319193632295217 0.749704977527484 -352.645624643312 96.4669167827115 -3.6556120627099 0.000282041643265288 PCDHAC1 other 1 1 1 0.319193632295217 -3.6556120627099 0.0102750705104657 0.842336675745293 2.64918640378787 0.317960515930816 0.750637807799466 -15.9757202425137 5.97695942551172 -2.67288417156118 0.00774762983442647 SEMA6A-AS1 other 1 1 1 0.317960515930816 -2.67288417156118 0.258619404934243 -9.68022776725502 5.88088574984928 -1.64604928220262 0.10036488969159 -5.45801616058353 27.8544414555187 -0.195947786973203 0.84472847511579 FGF10-AS1 other 1 1 1 -1.64604928220262 -0.195947786973203 0.000401619193816863 13.3433400161796 3.97534731120339 3.35652182604906 0.000844744810563793 93.3091278006403 44.4187049052675 2.10067195789797 0.0361319668279997 PCP4L1 other 1 1 1 3.35652182604906 2.10067195789797 3.15050442312179e-25 46.5125543284827 18.1150120328575 2.56762480997071 0.0105181370235943 -275.255582652947 33.1182374102861 -8.31129927728146 8.30028629552466e-16 ABHD14A other 4.08273868192353e-21 1.25359223921309e-11 1 2.56762480997071 -8.31129927728146 0.000273296156155712 1.92894863530931 0.489989625747405 3.93671321585021 9.33921220864569e-05 -3.01775215310279 4.24678780382356 -0.710596406626622 0.477640584549845 ZFAT-AS1 other 1 1 0.773847123608382 3.93671321585021 -0.710596406626622 2.89025662401114e-09 9.26219486282757 2.90673652793399 3.18645834385644 0.00152321348303196 -17.1230080182049 5.13238724201293 -3.33626579811411 0.000907303977973807 SRP14-AS1 other 2.3087369912601e-05 1 1 3.18645834385644 -3.33626579811411 5.38873729105432e-06 53.5457688438542 34.6394993240525 1.54580088883311 0.122745061479527 -215.957736314205 63.3186471261963 -3.41064988144477 0.000697126482551122 TMEM110-MUSTN1 other 0.0335341121622311 1 1 1.54580088883311 -3.41064988144477 6.80583009648445e-08 16.4197701784989 3.11383669392032 5.27316355753597 1.94819795043064e-07 -9.31102691048357 10.9190474827035 -0.852732523164945 0.394188523595214 DSTNP2 other 0.000498186763062662 1 0.00195735448079767 5.27316355753597 -0.852732523164945 3.50044792825243e-21 330.241885553537 38.2387552193026 8.6363136995326 7.40498669431146e-17 -388.670366651796 136.270034561725 -2.85220714812209 0.00451716882622005 RBM14-RBM4 other 4.24534324738455e-17 1 9.78791141254089e-13 8.6363136995326 -2.85220714812209 0.00124771793434921 5.98111817773859 1.63037493996536 3.66855379773298 0.000268337441631101 2.37614935858748 7.82686275321338 0.303588990060153 0.761559066735809 OXCT1-AS1 other 1 1 1 3.66855379773298 0.303588990060153 3.90757231244024e-25 5.60405999949088 0.532746801112139 10.5191809463559 1.55827164721498e-23 -2.27400926580552 2.38524108487753 -0.953366634602591 0.340860439102297 ALG1L9P other 5.05444478614145e-21 1 2.21025250440972e-19 10.5191809463559 -0.953366634602591 0.266396782680156 57.4384617122899 35.2776244780754 1.62818394271381 0.104061679980141 47.4447065920477 88.2703060152261 0.537493396520725 0.59114543177756 LY75-CD302 other 1 1 1 1.62818394271381 0.537493396520725 4.140102574534e-08 -2.4887211481142 4.12624677245682 -0.603144039936415 0.546665170001271 -39.5134675711055 7.62381963209033 -5.18289643222731 3.08800746911759e-07 CCDC153 other 0.000307982230519584 0.00400421928520478 1 -0.603144039936415 -5.18289643222731 0.892840408905984 13.219554733234 48.7294705707455 0.271284595921105 0.786281068592011 -52.3085592715882 170.604934915786 -0.306606366910833 0.759267169523312 ACTN3 other 1 1 1 0.271284595921105 -0.306606366910833 1.41888341209831e-11 3.31182806943026 1.84241456778295 1.79754770036123 0.0728287413223218 -26.5858702703209 4.549860250347 -5.84322788118454 9.03964613849265e-09 USP46-AS1 other 1.27642751752364e-07 0.000123770834928241 1 1.79754770036123 -5.84322788118454 1.01525379264931e-31 13.3327403514208 37.3533292245242 0.356935797376455 0.721278028397815 -757.343306900612 66.7682286313135 -11.3428695417782 6.42033936745727e-27 TNFSF12-TNFSF13 other 1.41150734792034e-27 1.00195816168538e-22 1 0.356935797376455 -11.3428695417782 1.15732914387017e-11 90.176152755877 51.0977003946401 1.76477908123897 0.0781619783078964 -489.615178052377 93.3779795635105 -5.24336872934125 2.26080732378668e-07 FMN1 other 1.04518394982915e-07 0.00294470153923214 1 1.76477908123897 -5.24336872934125 2.16566312664432e-27 185.943275081532 23.0896559242778 8.05309856895789 5.18734612944174e-15 -432.392052087585 73.1973356185463 -5.90721026159903 6.16192908365659e-09 ATP5J2-PTCD1 other 2.88682894781688e-23 8.47312756162126e-05 6.63202202649126e-11 8.05309856895789 -5.90721026159903 0.622723221412887 2.45477222660103 2.95038682600016 0.832017078224607 0.405764381648478 5.29909236382651 6.83646523281874 0.775121672291698 0.438604559364211 C5orf66-AS1 other 1 1 1 0.832017078224607 0.775121672291698 2.92324464473608e-06 1.18080555812244 4.32699081110987 0.272893012643021 0.785038827682629 -28.7813215101236 6.84910850148829 -4.2021996737049 3.08852658585925e-05 ZNF436-AS1 other 0.0186999959923767 0.360956102089371 1 0.272893012643021 -4.2021996737049 0.00314599346831851 -1.37640871525169 1.1215384612083 -1.22725056951575 0.220258278805237 5.53761582769849 2.33941397166526 2.3670953045376 0.0182767550983906 LINC02362 other 1 1 1 -1.22725056951575 2.3670953045376 3.81164444301434e-34 132.200074261546 10.1871875685235 12.9770923890731 9.51610091315823e-34 -40.2834237562603 55.0084114504545 -0.732313889713814 0.464291809683048 HAUS5 essential 5.40453065575003e-30 1 1.416757103951e-29 12.9770923890731 -0.732313889713814 0.000175543461755565 21.1287772698545 38.4488367962463 0.549529687512349 0.582876562938539 -375.050456083619 100.946845176927 -3.71532617414914 0.000224787506094517 PCDHA11 other 0.922831978449004 1 1 0.549529687512349 -3.71532617414914 0.204118785092862 2.95975983323762 2.21936604452405 1.33360598200571 0.182888068249228 7.37185118409807 4.39132696827345 1.67872974100047 0.0937758451300584 ATP5L2 other 1 1 1 1.33360598200571 1.67872974100047 0.336004246367046 -4.68101767697034 9.58092206455006 -0.488576949633101 0.625344862020851 16.1461606633185 20.9744114869284 0.769802798680719 0.441762444739034 CASC16 other 1 1 1 -0.488576949633101 0.769802798680719 0.00243886952183004 467.912427870865 283.426726467215 1.65091144968289 0.0993391526126233 -1457.03228644532 655.697424303443 -2.222110736508 0.0266901765917972 TMEM150C other 1 1 1 1.65091144968289 -2.222110736508 0.000219463852194574 0.722007378181006 1.75924335391648 0.41040790438324 0.681668041298102 -15.3507826009176 4.00839215843793 -3.82966087003318 0.000143229219250576 LINC00939 other 1 1 1 0.41040790438324 -3.82966087003318 0.00300773747116063 -37.4045986206548 16.3858108205869 -2.28274322401307 0.0228347938429718 -145.033741865978 45.2827497573474 -3.20284750027675 0.00144126442228523 LINC01411 other 1 1 1 -2.28274322401307 -3.20284750027675 2.95433881239191e-08 33.9680140747681 6.03917874221169 5.62460816689262 2.97711648540709e-08 10.2394782849972 12.5320418171417 0.817063845972118 0.414249619054137 APOBEC3B-AS1 other 0.000222254908856243 1 0.000312448375143474 5.62460816689262 0.817063845972118 0.521769045762625 -17.833089983888 20.0405407530926 -0.889850738240986 0.373940102552525 -65.4629338813579 67.7289444190937 -0.966542952098675 0.334202842324757 LINC01016 other 1 1 1 -0.889850738240986 -0.966542952098675 1.52933476385448e-28 3.49137613697486 2.36454455200807 1.47655333201899 0.140370853860889 -46.1107699181038 4.78994206790312 -9.62658196371247 2.2807381312614e-20 UGDH-AS1 other 2.06337846339246e-24 3.51575782933945e-16 1 1.47655333201899 -9.62658196371247 3.63496949453152e-09 26.5482186711328 22.8461451035802 1.16204368617848 0.245754918752009 -278.117418583774 52.5149960368683 -5.29596190750012 1.75553071377431e-07 NAIP other 2.8894372512031e-05 0.00229763859818782 1 1.16204368617848 -5.29596190750012 0.00115299958159448 21.8777105955682 5.92908914015243 3.68989402561179 0.000247357324631386 19.6423179475133 15.3964971916818 1.27576537071857 0.202593130129574 ZNF286B other 1 1 1 3.68989402561179 1.27576537071857 1.5238624717741e-25 30.8510728079912 3.29144018964265 9.37312271542164 2.35167895169702e-19 -47.3733829151793 12.0678364280625 -3.92559040699436 9.85215892056996e-05 ZNF324B other 1.98376416575552e-21 1 3.21145277643745e-15 9.37312271542164 -3.92559040699436 5.99709569099914e-22 19.5903780443724 3.57128457040797 5.48552703044174 6.30979978312879e-08 -42.8825837288422 7.74183935204868 -5.53906917708057 4.72962662848889e-08 MIR302B other 7.38242479561994e-18 0.000632776746625529 0.000652054709588529 5.48552703044174 -5.53906917708057 0.000468373408850429 12.8406441848181 3.35928470176444 3.82243403724418 0.000147645832295324 1.00277218963611 10.344559963033 0.0969371527855787 0.922812538783204 HOXC13-AS other 1 1 1 3.82243403724418 0.0969371527855787 0.642203789978809 27.4457782250931 31.6003932615363 0.868526476804953 0.385486386932287 -3.28133950698545 75.3192051835949 -0.0435657744792579 0.965266403058289 MIR143 other 1 1 1 0.868526476804953 -0.0435657744792579 3.74347433416705e-40 72.4359727204325 12.3135425279442 5.88262659231063 7.0728342992521e-09 -209.873003552554 24.064026606141 -8.72144163516658 3.37274326434623e-17 NOP14-AS1 other 5.48606163672182e-36 5.13736254025218e-13 7.61956439058429e-05 5.88262659231063 -8.72144163516658 4.11694769788174e-05 40.6105959769174 11.8786324096721 3.41879389616017 0.00067712136645696 -48.2706210191085 29.4679694293499 -1.63807082584493 0.101997082452439 SRD5A3-AS1 other 0.235530577795814 1 1 3.41879389616017 -1.63807082584493 4.80511861881342e-21 46.5850137014842 6.73711079437115 6.91468718911465 1.35646205085512e-11 -132.484619111959 24.6743810324681 -5.36931884684877 1.18525428003235e-07 ZNF564 other 5.81131045759295e-17 0.00156453564964271 1.60320249790566e-07 6.91468718911465 -5.36931884684877 0.757267216385208 -0.496917631329119 1.98880535490523 -0.249857347831205 0.8027963427105 -5.51017344817828 7.48029887749455 -0.736624771071161 0.46168275831826 FER1L5 other 1 1 1 -0.249857347831205 -0.736624771071161 0.000183456620049751 0.224909626227247 12.6218214073535 0.0178191101718659 0.985789704848592 -117.206412557273 30.0133993916891 -3.9051362035894 0.000106036957072056 ECSCR other 0.962596885401045 1 1 0.0178191101718659 -3.9051362035894 0.0224338058397019 -79.6482655787813 47.1977264861482 -1.68754453887004 0.092071904600408 -283.675876999646 105.820436522582 -2.68072865999859 0.00756905631539397 VCAN-AS1 other 1 1 1 -1.68754453887004 -2.68072865999859 3.33214281344179e-05 83.6383411296709 26.9939769733597 3.09840751558073 0.00204651901989854 -270.904627446081 96.6530679121414 -2.80285595996121 0.00524656358468417 RNF103-CHMP3 other 0.19233128319186 1 1 3.09840751558073 -2.80285595996121 3.87378734903175e-15 3.58666608610217 0.434255771582462 8.25934004983301 1.20702090378202e-15 -0.742594677236911 1.98882212878983 -0.373384158637037 0.709013843591748 BRD9P2 other 4.01789223841573e-11 1 1.56007451813826e-11 8.25934004983301 -0.373384158637037 4.18023327622904e-26 404.745805899964 39.113328286582 10.3480277345463 5.92798072792366e-23 -541.519024003557 171.82578956782 -3.1515584788849 0.00171725285482744 PDCD6 other 5.48613815172299e-22 1 8.36675199939145e-19 10.3480277345463 -3.1515584788849 5.74702418705673e-05 4.16548126628715 0.943101714460234 4.41678898725275 1.22168178028003e-05 -6.40678347104194 11.1994453545456 -0.572062568120087 0.56752920072027 LINC00536 other 0.322293116410141 1 0.109316085699457 4.41678898725275 -0.572062568120087 8.1009755009946e-07 81.4728163256312 45.0565991496784 1.80823270870884 0.0711183467404813 447.006039431106 84.3394949793148 5.30007963102861 1.68045259649511e-07 TMEM158 other 0.00545600699991986 0.00220122485614895 1 1.80823270870884 5.30007963102861 4.53279546636676e-161 446.184522167038 11.6506589721729 38.2969343822296 1.12607649587948e-156 -344.775853669254 72.7588915883568 -4.73860783393828 2.74925672592715e-06 C15orf38-AP3S2 other 7.1015306571568e-157 0.0342282462377931 1.76422404609438e-152 38.2969343822296 -4.73860783393828 0.29712716865953 -0.0137111151668125 2.04724644712987 -0.00669734471198363 0.994658800853263 14.4963309961153 9.37414516288496 1.54641631255195 0.122588798584172 LINC01018 other 1 1 1 -0.00669734471198363 1.54641631255195 1.46973018092042e-05 18.1178714045631 5.11448612959121 3.54246173427616 0.000431384461824107 -33.1474835081624 16.660359140512 -1.98960197848074 0.0471482593087045 YJEFN3 other 0.0880956270443702 1 1 3.54246173427616 -1.98960197848074 0.000222830171622731 33.0521244122862 45.046507730266 0.733733336448611 0.463445164295788 -434.801967799647 121.491855990989 -3.57885690569987 0.000377724409091382 PCDHA10 other 1 1 1 0.733733336448611 -3.57885690569987 5.13155622384462e-09 10.1938882449104 1.70425651610533 5.98142835223308 4.04944893928258e-09 18.5432480965791 5.27931222456845 3.51243633787825 0.000481563014071973 HOXC-AS2 other 4.04007421503287e-05 1 4.39689165827303e-05 5.98142835223308 3.51243633787825 0.00197717106434758 -25.3254710639194 7.1358415601314 -3.54905176222173 0.000420068886981852 -17.9977321810898 16.7001909280367 -1.07769619273482 0.28164700698804 FZD10-AS1 other 1 1 1 -3.54905176222173 -1.07769619273482 7.54079289459053e-11 -10.3132419946155 13.0227666647864 -0.791939398138995 0.428748318413331 -158.505514620875 26.7365922612887 -5.92841126018784 5.49961854353972e-09 KIAA1456 other 6.54917862895187e-07 7.57297473445419e-05 1 -0.791939398138995 -5.92841126018784 4.96604734467882e-07 27.810723249563 9.20841743463885 3.02014145720075 0.00265685102961065 -57.0312373198377 20.4356110575783 -2.7907771957075 0.0054608013509458 ZNF718 other 0.00340074922163606 1 1 3.02014145720075 -2.7907771957075 2.17550522983016e-10 61.4465341683027 13.1745133195957 4.66404584956526 3.90989115360692e-06 -45.1335618767928 23.9435632837643 -1.88499770656096 0.0599648639018512 SMIM20 other 1.84939699587862e-06 1 0.0362368712116289 4.66404584956526 -1.88499770656096 0.868771352146579 -0.992272540922633 20.7824058502918 -0.0477457974822824 0.961936325505889 20.1119065562063 42.9930086612564 0.467794815540099 0.640118329539511 TUNAR other 1 1 1 -0.0477457974822824 0.467794815540099 0.00480253370351006 3.70886126427334 1.1344180415994 3.26939552111165 0.00114707965845169 4.19347579989307 3.51411127268156 1.1933247055928 0.233271138842262 HOXC-AS1 other 1 1 1 3.26939552111165 1.1933247055928 1.03094272179319e-11 200.544756570883 31.0765561479867 6.45324905423525 2.41429748524909e-10 6.27476362742121 70.6686794946724 0.0887912958369947 0.92928027366075 CHCHD10 other 9.33518634583736e-08 1 2.74819482745904e-06 6.45324905423525 0.0887912958369947 0.00800536950952373 4.82083340861346 1.54469842024782 3.1208897124657 0.00189946831378772 3.76842139193248 3.38956492924611 1.11177141332137 0.266731173102527 FAM218A other 1 1 1 3.1208897124657 1.11177141332137 1.26271156950763e-09 21.4613398332902 3.29076818329517 6.52168084711458 1.590666147484e-10 12.6620087498791 11.5593470270935 1.09539135041116 0.273829939262831 CDK3 other 1.02772094642226e-05 1 1.82019927256594e-06 6.52168084711458 1.09539135041116 0.00245195253628053 -15.1045142789039 7.76519484927507 -1.94515586177648 0.0522836680967251 -94.0620589749136 28.7809145475888 -3.2682095219519 0.00115233528119807 GPR162 other 1 1 1 -1.94515586177648 -3.2682095219519 1.98736189105749e-15 59.4852184304621 7.00829842586568 8.48782611923584 2.00053906718926e-16 34.4464851563963 24.1655057995465 1.42544027185406 0.154602430063937 ATP6V1E2 other 2.07997295518077e-11 1 2.62230660927168e-12 8.48782611923584 1.42544027185406 4.82453701188156e-13 52.8620541183724 6.92536308593307 7.63310940703554 1.12951565292366e-13 -22.0440869143848 48.3834911847107 -0.455611746374987 0.648862355803881 GLI4 other 4.61081002225521e-09 1 1.40466566597586e-09 7.63310940703554 -0.455611746374987 0.716501381113967 -10.7844576391299 15.3807239561784 -0.701167101747365 0.48350881135549 -36.4549070289499 70.5270508630667 -0.516892548076761 0.605448432639537 LINC01511 other 1 1 1 -0.701167101747365 -0.516892548076761 0.413681142785368 1.10010931317063 4.06531846758736 0.27060839684314 0.786796601042792 -7.82094330617242 7.9831808829057 -0.979677577257372 0.327688093000943 CCDC169-SOHLH2 other 1 1 1 0.27060839684314 -0.979677577257372 0.00166941533962877 952.808452908449 453.066456992999 2.10302139609327 0.0359419906416159 -5464.57301051192 2126.63415914371 -2.56958771541233 0.0104584236940462 SELENOP other 1 1 1 2.10302139609327 -2.56958771541233 5.79097138562369e-12 12.5697037006205 2.37354570049069 5.29574960280811 1.72447733495764e-07 -25.0600045179975 6.82523870901482 -3.6716671147191 0.000264801193274443 NT5C1B-RDH14 other 5.31321624630974e-08 1 0.00173706601950283 5.29574960280811 -3.6716671147191 9.78576690036896e-06 5.91635852769472 11.6984045785487 0.505740632234889 0.613245116307867 -163.473633069134 36.1602730916371 -4.52080747993413 7.57628592454322e-06 LINC02381 other 0.0595561773556455 0.0921579419861437 1 0.505740632234889 -4.52080747993413 0.44538969784749 -4.51375834289282 8.38965464381211 -0.538014797333999 0.590786066073317 -47.6444552090208 39.439457761631 -1.20804032086293 0.227554728188444 SNHG18 other 1 1 1 -0.538014797333999 -1.20804032086293 4.48408336721153e-07 16.90293647006 4.65403691555163 3.63188706423411 0.000308226580794323 -27.5298700204936 10.7905705060091 -2.551289573166 0.0110075598684408 SMAD1-AS1 other 0.00308460094830481 1 1 3.63188706423411 -2.551289573166 9.76407916050953e-07 6.98919302988051 2.72433205429199 2.56547032101669 0.0105785892401042 -26.1355025658353 7.15997385419926 -3.65022318489433 0.000288078628672671 GLUD1P3 other 0.00652435769505247 1 1 2.56547032101669 -3.65022318489433 3.22402909046783e-07 12.6478804069951 2.36799013997535 5.34118795238174 1.37075603393758e-07 15.0137939782294 4.99658312364963 3.00481221000141 0.00278270290421006 SNHG21 other 0.00224392424696561 1 0.0013878904843618 5.34118795238174 3.00481221000141 5.85070559703348e-10 127.422520947347 26.7307840932877 4.76688302530353 2.41136010959819e-06 -156.620714882297 63.0321370828385 -2.48477557847138 0.0132662488419723 THAP9-AS1 other 4.85199015161986e-06 1 0.0226933099914286 4.76688302530353 -2.48477557847138 1.03293566755395e-09 24.992933758348 3.81822729506807 6.545690402096 1.38938857316014e-10 16.4184816713885 11.8278051716647 1.38812581312394 0.165676492883165 HOXC-AS3 other 8.44793007828647e-06 1 1.59348975455736e-06 6.545690402096 1.38812581312394 8.40135677226533e-12 6.10295852009327 2.20314651816773 2.7701101446348 0.00579450922236573 -26.4112387388297 5.07310728149249 -5.20612659526877 2.73492237941902e-07 LINC01843 other 7.64439452708423e-08 0.00355239067862736 1 2.7701101446348 -5.20612659526877 1.03632998324347e-09 47.4226118183863 21.0743790549229 2.2502495421002 0.0248348030651565 -229.83669612017 47.3147408755539 -4.85761291020659 1.55876249401664e-06 TMED7-TICAM2 other 8.47407027298181e-06 0.0196170259871995 1 2.2502495421002 -4.85761291020659 2.1511143723135e-13 11.5393144851817 2.35422104810782 4.90154248449029 1.25745168670148e-06 -52.857165083354 10.8498159988251 -4.87171073583901 1.45374573001084e-06 ZNF345 other 2.08851694407918e-09 0.0183215574353266 0.0120375849967933 4.90154248449029 -4.87171073583901 0.393826087504753 21.1849036008512 23.7081140563964 0.893571861112909 0.371962000398303 -29.2632464036475 50.8143674854522 -0.575885283075212 0.564940436541993 SHANK3 other 1 1 1 0.893571861112909 -0.575885283075212 1.47118287308224e-24 64.7842203110709 6.05008713735803 10.7079813629529 2.07368939484279e-24 -26.5232203716309 30.3886948974391 -0.8727989293764 0.383157760847202 ZNF550 other 1.88929304561222e-20 1 2.9587400285617e-20 10.7079813629529 -0.8727989293764 0.000710511065226847 -3.34451789908897 1.55679865703431 -2.14833041124294 0.0321283324980935 7.84048516660386 3.59572430415177 2.18050231424888 0.0296480028543327 DCANP1 other 1 1 1 -2.14833041124294 2.18050231424888 0.102320309465035 4.83022376875225 5.00890827744047 0.964326655871702 0.335315427165386 -15.6240226686259 11.3331848983325 -1.37860829138372 0.168588512534982 LINC00958 other 1 1 1 0.964326655871702 -1.37860829138372 8.72900372568561e-05 12.4939085990904 6.06153997502571 2.06117729992161 0.0397643147521219 -66.0628036673424 19.5095749184825 -3.38617340169505 0.000760332231568563 RPL32P3 other 0.477651083869517 1 1 2.06117729992161 -3.38617340169505 0.10717766964322 6.03319882262068 12.1029449229777 0.498490149382283 0.6183393567757 59.6497528824103 28.545821782652 2.08961414166261 0.0371146796719189 FOXD1 other 1 1 1 0.498490149382283 2.08961414166261 0.702582950889281 857.466411310486 1021.43217600174 0.839474643012445 0.40158878086668 843.759048072697 2627.9054509107 0.321076638347202 0.748281315949221 MALAT1 other 1 1 1 0.839474643012445 0.321076638347202 2.65814948651296e-18 17.1478050727559 4.72375549279769 3.63012122428884 0.000312587328399884 -64.7538900233958 10.464503525637 -6.18795625275056 1.27360623997177e-09 ABCA11P other 3.02284759606254e-14 1.78011944160854e-05 1 3.63012122428884 -6.18795625275056 0.000123429666586753 21.0969294602363 37.7791838219067 0.558427348766677 0.576791133279575 -375.0922021472 98.6536176725647 -3.8021129989591 0.00016034337311674 PCDHA12 other 0.663928176570143 1 1 0.558427348766677 -3.8021129989591 1.67392003977549e-27 11.7864654455501 5.42815622928298 2.17135707737488 0.0303388857596565 -96.0840622460639 10.7074664732331 -8.9735571422295 4.73260209182477e-18 FAM86EP other 2.23501803710824e-23 7.23851489944599e-14 1 2.17135707737488 -8.9735571422295 0.810344350039327 -16.5970741777439 33.9900370967697 -0.488292323144339 0.62553847899758 -36.9860835269262 66.6325295413926 -0.555075483123453 0.579069941632937 SCARNA5 other 1 1 1 -0.488292323144339 -0.555075483123453 0.750113858073588 -7.07601155609838 13.3621651284813 -0.529555763460516 0.596635612073432 -19.5349941086021 27.6425975529618 -0.706698929837329 0.480055618843765 SCARNA13 other 1 1 1 -0.529555763460516 -0.706698929837329 0.0108600677924309 29.0489538727263 79.8665550560292 0.363718628559194 0.716210749787915 -517.253040483052 194.085118310018 -2.66508346949521 0.00792765910315466 PCDHGA12 other 1 1 1 0.363718628559194 -2.66508346949521 0.666256539868511 7.52129420749739 8.90811088582642 0.844319778221937 0.398878255717483 17.0923597140454 37.2661348101322 0.458656627555541 0.646672032601455 HOXA10-AS other 1 1 1 0.844319778221937 0.458656627555541 8.43469274525015e-09 9.69113519439191 4.84518479718958 2.00015801255159 0.0460098577705674 -52.4028108038421 11.202205156922 -4.67790136582723 3.71199772637022e-06 GUSBP3 other 6.55291279378484e-05 0.045861731909304 1 2.00015801255159 -4.67790136582723 0.718925508786199 0.3725642491065 1.77550098654302 0.209836126214663 0.833877135470022 14.2104970444657 17.7904932529433 0.798769142733841 0.424786171671596 C8orf88 other 1 1 1 0.209836126214663 0.798769142733841 8.64820458399104e-08 133.228429267347 25.272831479419 5.27160675984572 1.95485396002679e-07 -50.9382013380041 77.0433802780727 -0.661162596373015 0.508788471223077 CCDC71L other 0.000628119098935269 1 0.00196384628824291 5.27160675984572 -0.661162596373015 0.647733186296777 14.9857474759105 16.4685196610315 0.909963238005563 0.363262673075874 24.7221053119006 68.8943011236861 0.358841078415425 0.719859349279881 HOXA10 other 1 1 1 0.909963238005563 0.358841078415425 0.0140411956820461 69.8190675464032 47.5778532750815 1.46746989912995 0.142828296265778 -118.007971554004 76.8582809817873 -1.53539696759505 0.12526986632574 TMEM200B other 1 1 1 1.46746989912995 -1.53539696759505 0.0133858598112683 29.6162652060024 79.4873964597917 0.372590706515134 0.709599551644736 -508.748283773456 196.363807794675 -2.59084547955712 0.00983330521683335 PCDHGB6 other 1 1 1 0.372590706515134 -2.59084547955712 6.29498839701813e-14 5.38485951833758 1.80123859543708 2.98953149903548 0.00292254847295946 -16.067071526347 3.31924976350357 -4.84057322320562 1.6965972585665e-06 SERPINE3 other 6.24085149680377e-10 0.021314351359371 1 2.98953149903548 -4.84057322320562 4.05947152316212e-06 29.8568637489794 12.4291112502284 2.40217205783163 0.0166340873103238 -95.7944591774363 27.9920986978213 -3.42219639233025 0.000668163641002623 C1orf210 other 0.0255746705959214 1 1 2.40217205783163 -3.42219639233025 1.24529108803484e-35 15.1054500556889 1.10096479681245 13.7201935061163 9.56604505354169e-37 -7.71581705948092 12.8583169664145 -0.600064306987796 0.548726804705637 RAD21-AS1 other 1.78475118737154e-31 1 1.43519373938286e-32 13.7201935061163 -0.600064306987796 0.050159198970017 12.9205322643306 14.7063418686929 0.878568741274544 0.380023745552458 -33.481129036271 22.8178538023806 -1.46732156872606 0.14286754318166 TRNP1 other 1 1 1 0.878568741274544 -1.46732156872606 0.00959425495178347 37.6055419323037 80.6770324976058 0.466124506171192 0.641314347050724 -528.012479900112 199.35263177071 -2.64863561223219 0.0083182212748159 PCDHGA5 other 1 1 1 0.466124506171192 -2.64863561223219 0.00138547627569355 -47.0184638677179 17.6541772361006 -2.66330530383319 0.00798382438261305 -186.019593017936 63.2977375727749 -2.9388031887248 0.00344498968074111 NACA2 other 1 1 1 -2.66330530383319 -2.9388031887248 0.0108860631645383 29.6086472167887 79.2666348922463 0.373532284510857 0.708898919771267 -520.136252854407 195.836349117004 -2.65597400686655 0.00814168681310644 PCDHGA7 other 1 1 1 0.373532284510857 -2.65597400686655 0.651018104101361 -0.832906222649835 1.09259808012618 -0.762317120815044 0.446219749054727 -6.44135271577531 11.9454001185731 -0.539232897335942 0.589959199499099 CA3-AS1 other 1 1 1 -0.762317120815044 -0.539232897335942 1.18595161140584e-27 5.01231887224538 0.430561522991419 11.6413534526291 5.52359703438696e-28 -3.93092333572299 4.44682444874017 -0.883984376049893 0.3771147443143 SLC10A5 other 1.58573589961074e-23 1 8.04456672088117e-24 11.6413534526291 -0.883984376049893 0.003190220104491 47.9728900472467 27.3590037960433 1.75345894919553 0.0800916543550418 325.602066402925 102.094260966161 3.18922986778703 0.00150941929961051 EIF5AL1 other 1 1 1 1.75345894919553 3.18922986778703 3.93020086147271e-15 43.6147299689449 19.5043669865193 2.2361520370843 0.0257556224970981 -194.034740052094 33.9618381266748 -5.71331679187564 1.8460200205477e-08 ALG11 other 4.07404621300262e-11 0.000250246473985446 1 2.2361520370843 -5.71331679187564 1.59050663150133e-19 30.4210133642476 3.2004987562654 9.50508520107825 7.75514942644781e-20 -21.0684517363989 22.3063343185904 -0.944505333574245 0.345357838707983 MINCR other 1.86518712676161e-15 1 1.06454936176849e-15 9.50508520107825 -0.944505333574245 2.36958727216627e-16 869.335393697474 110.265182534777 7.88404257548198 1.84581977089512e-14 -732.838644801904 344.670154440953 -2.12620279232053 0.0339523174904611 ATXN7L3B other 2.55465203812245e-12 1 2.33588492006778e-10 7.88404257548198 -2.12620279232053 4.50136411187365e-28 2160.82493239865 182.633375331346 11.8314898822755 2.6643710904493e-28 -1039.76535471803 1528.30139102569 -0.680340514523911 0.496639527457161 PRKDC ts 6.04623227506868e-24 1 3.88731742096553e-24 11.8314898822755 -0.680340514523911 0.0124059020393604 32.5535942883064 79.774917224901 0.408068042195913 0.683385468461591 -511.954873462712 197.092112736629 -2.5975411514657 0.00964553292087907 PCDHGA6 other 1 1 1 0.408068042195913 -2.5975411514657 4.8925514211633e-50 128.83433831815 7.76796497248694 16.5853397607305 5.97305261397899e-50 -138.738485063801 78.5583758519267 -1.76605592413604 0.07796982186754 OTUD6B-AS1 other 7.39949476936737e-46 1 9.1531058256614e-46 16.5853397607305 -1.76605592413604 0.0118426524201574 29.4193544091955 80.5525342031651 0.365219476956438 0.715090847523304 -524.102749534554 198.995099199727 -2.63374702011392 0.00868742502887011 PCDHGA8 other 1 1 1 0.365219476956438 -2.63374702011392 2.00773503886447e-23 96.4253155140959 42.0867177662405 2.29111037001423 0.0223470961690844 -565.963639894193 73.2831932996347 -7.72296640486345 5.68095327095286e-14 UTP14C other 2.53195465751198e-19 8.45496275315915e-10 1 2.29111037001423 -7.72296640486345 0.0010364458240102 4.49792984514925 1.25311822882605 3.58938984501327 0.000361579609961261 11.8685967708577 11.28571766239 1.05164750048729 0.293430810560654 ETV3L other 1 1 1 3.58938984501327 1.05164750048729 0.0130960017126191 44.2885929554807 82.2242548669711 0.538631733752215 0.590363361323349 -510.56219549542 203.124878884737 -2.51353846116083 0.0122431236770062 PCDHGA10 other 1 1 1 0.538631733752215 -2.51353846116083 0.014420330321726 23.6875993197813 78.7037826093011 0.300971548437139 0.763552039380491 -501.772605362389 192.28832221943 -2.60948038638452 0.00931947081960616 PCDHGA11 other 1 1 1 0.300971548437139 -2.60948038638452 0.0111199718884048 43.3115776045922 79.9768384338603 0.541551509821313 0.588350863151992 -506.441644573454 197.62245497768 -2.56267256992963 0.0106569581760496 PCDHGB2 other 1 1 1 0.541551509821313 -2.56267256992963 0.0159388258917026 33.0820470109113 82.9005166463211 0.399057187448535 0.690009121738406 -516.256059650921 204.795500190422 -2.52083692840369 0.0119950582655447 PCDHGB4 other 1 1 1 0.399057187448535 -2.52083692840369 4.63156634360687e-05 46.1731564676604 12.9370639203364 3.56905993137117 0.000390487426019326 0.871348609094161 26.8701367496631 0.0324281419634043 0.97414271437507 CLDN23 other 0.263536124951231 1 1 3.56905993137117 0.0324281419634043 5.120304950755e-23 189.861554031651 19.4367858998697 9.76815585713293 7.29947631889266e-21 -148.443750855773 86.1697123733233 -1.72269056919503 0.0855170270844773 ZNF260 other 6.41625413379109e-19 1 1.01199939685128e-16 9.76815585713293 -1.72269056919503 0.0230030696707888 11.1351105633621 20.8079909401841 0.535136265455504 0.592788883087379 449.983686972103 163.628766325486 2.75002798760339 0.00617064422627469 LYN other 1 1 1 0.535136265455504 2.75002798760339 3.47035833847403e-42 57.6138098460562 4.73619215155623 12.1645845443845 2.89555354235688e-30 -12.8674702375345 12.0408864663817 -1.06864808280194 0.285704864638686 PINX1 other 5.12918962426461e-38 1 4.26051748222391e-26 12.1645845443845 -1.06864808280194 3.39468876623368e-22 7.64343582412459 1.69000992878908 4.52271652013385 7.52493629502229e-06 -16.2916415377715 3.47838908181363 -4.68367429709072 3.57729366696049e-06 RBPMS-AS1 other 4.19719319057132e-18 0.0442403907793004 0.0684242457306376 4.52271652013385 -4.68367429709072 0.012855893945722 27.8392227290565 80.1484257591509 0.347345845727706 0.728467097864332 -517.945699941002 197.996799137543 -2.61592966248509 0.00914793848174994 PCDHGB7 other 1 1 1 0.347345845727706 -2.61592966248509 5.06142911540326e-06 43.5803830566689 10.8580214930875 4.01365783668904 6.83175581573832e-05 -124.925259714588 65.3679651097505 -1.91110828530217 0.0565247576809871 NPIPB11 other 0.0315681333927702 1 0.573115995382288 4.01365783668904 -1.91110828530217 0.0178640675417399 53.3450609807508 80.8110707577767 0.660120704756498 0.509457835712918 -467.239369637807 199.683839787364 -2.33989575789084 0.0196524699870033 PCDHGB1 other 1 1 1 0.660120704756498 -2.33989575789084 0.0117365616105498 32.9503367545912 78.3144045552892 0.420744267184315 0.674109224108117 -504.62307783541 193.514587365572 -2.60767461877237 0.0093681448882345 PCDHGA3 other 1 1 1 0.420744267184315 -2.60767461877237 3.97274416073685e-23 4.16217113615003 0.398824442201903 10.4360984326105 2.62054563754318e-23 -4.05184955351834 3.73889311864985 -1.08370296366789 0.278991130600945 SNORD87 other 4.98897211705333e-19 1 3.71016851363363e-19 10.4360984326105 -1.08370296366789 0.396777099725206 -19.2021211602788 15.2977368038646 -1.25522627343333 0.209957187556384 19.081646535593 63.998012712143 0.298159985395491 0.765699473703141 HOXA-AS3 other 1 1 1 -1.25522627343333 0.298159985395491 6.37818850657258e-36 33.9431687020412 2.4586452277254 13.8056391053391 4.41222915898184e-37 20.4616165463221 16.6772641040938 1.22691686229873 0.220417716785519 RHPN1-AS1 other 9.15716523888626e-32 1 6.62496208221123e-33 13.8056391053391 1.22691686229873 2.56510977299466e-11 32.5072346730771 5.22354420714082 6.22321423615756 1.04340123946082e-09 -95.556980087437 35.5612024324486 -2.68711330189004 0.00745125416458796 LRRC24 other 2.27961305526035e-07 1 1.16099255914806e-05 6.22321423615756 -2.68711330189004 8.55950135485194e-08 114.899855950542 39.6041767548963 2.90120551328812 0.00387386536662244 -287.225746748949 84.884912684109 -3.38370786594117 0.000768772610649965 CHKB-CPT1B other 0.000622190153484187 1 1 2.90120551328812 -3.38370786594117 0.556870006566975 -0.829514360275969 2.96873654284807 -0.279416630038909 0.780030727338572 11.8412621159519 12.0983649638564 0.978748959163271 0.328136701687782 SIGLEC14 other 1 1 1 -0.279416630038909 0.978748959163271 0.0285859134308299 -6.3523317642133 2.80973048406093 -2.26083312981401 0.024170509320201 -14.278350487633 6.42230605594592 -2.22324354573755 0.0266163592554332 SPON1-AS1 other 1 1 1 -2.26083312981401 -2.22324354573755 0.00939843602123381 8.73789733654359 3.77749498140101 2.3131459815475 0.0210866791985526 -10.9785148701489 10.0109824482977 -1.09664710000722 0.273280901463513 NAV2-AS2 other 1 1 1 2.3131459815475 -1.09664710000722 7.23883616141193e-08 64.5409061876346 13.338609241787 4.83865334216718 1.71661474783667e-06 -56.4292235791867 35.8906280816316 -1.57225511492418 0.11648814983418 AP5B1 other 0.00052894175831437 1 0.0162855241127265 4.83865334216718 -1.57225511492418 2.58425553763395e-21 188.332252267734 30.5732321555894 6.16003735912834 1.42883826597549e-09 -532.178002018922 87.4839617672219 -6.08314931409881 2.24325414313008e-09 CHMP4A other 3.14038732933278e-17 3.11745028270787e-05 1.58000935451569e-05 6.16003735912834 -6.08314931409881 3.73198633637181e-06 -0.374794566247611 4.7242989743155 -0.0793333716357176 0.936797017335244 45.6931612153753 9.85729215950693 4.63546788265844 4.47627869445144e-06 PABPC4L other 0.0236197415228972 0.0551298484008639 1 -0.0793333716357176 4.63546788265844 0.0645090854905647 -3.67794723796283 1.81627338785885 -2.02499649146908 0.0433704075854755 -7.04569833538397 3.58954594855468 -1.96283831893026 0.0501895593834649 MAGEL2 other 1 1 1 -2.02499649146908 -1.96283831893026 0.046979447533511 58.3772885075271 28.7096026368928 2.0333715254042 0.0425025682354287 129.364591718384 61.1910577372264 2.11410942222827 0.0349628506985968 CSNK2A3 other 1 1 1 2.0333715254042 2.11410942222827 2.71309627880796e-13 24.5651648865381 3.14867805324224 7.8017391651849 3.2324154711828e-14 26.5821677741168 18.956693770729 1.40225759278563 0.161419381354851 SMG1P6 other 2.62464934011882e-09 1 4.07252025214321e-10 7.8017391651849 1.40225759278563 2.73905547818698e-06 23.613216026361 19.8723512143166 1.18824470097677 0.235257419518376 -168.489192291567 39.8889129826145 -4.22396048658943 2.81574341055627e-05 FPGT other 0.0175628237261349 0.330117757453618 1 1.18824470097677 -4.22396048658943 0.418219940167231 574.951094271117 494.769127379578 1.16205935749509 0.245719057039438 -17.4507964028965 1158.93491967648 -0.0150576154938605 0.987991715447205 IGLL5 other 1 1 1 1.16205935749509 -0.0150576154938605 9.18483274958251e-09 325.603974649965 52.9331829702402 6.15122606235533 1.50319627207248e-09 -366.510512192242 477.405257201663 -0.76771360738791 0.442994781963287 MEX3A other 7.12008234747637e-05 1 1.65997964324964e-05 6.15122606235533 -0.76771360738791 1.03409561929346e-10 934.225138929566 497.086806542628 1.87940039170895 0.0607520574221148 -6742.15325060367 1245.60799795782 -5.41274081545517 9.51471555849482e-08 EEF1G essential 8.90769966459387e-07 0.00126012892856705 1 1.87940039170895 -5.41274081545517 1.04733148989782e-37 59.0369370449535 9.2781659157205 6.36299647809962 4.24254216462046e-10 -129.84788585651 20.149258964469 -6.44430080954753 2.58626298534538e-10 CKLF-CMTM1 other 1.51758332886194e-33 3.66938992360802e-06 4.79364839180466e-06 6.36299647809962 -6.44430080954753 4.21267335148937e-07 201.463802243894 50.0465785560966 4.02552598112328 6.49469107793168e-05 -1055.57425837872 331.179921528027 -3.18731357115014 0.00151879982735521 SYS1-DBNDD2 other 0.00290590207785737 1 0.546138572743275 4.02552598112328 -3.18731357115014 9.28592315427005e-06 6.11370260543518 3.78217717219672 1.61645061219707 0.106576643598094 -25.1488836148921 7.58413234819924 -3.31598691323779 0.000974114564484472 SLC22A18AS other 0.0566534171642016 1 1 1.61645061219707 -3.31598691323779 0.403006929917142 -5.15999095330956 6.62877640985432 -0.778422839189255 0.436658220171509 10.5644935229339 15.3316494625357 0.689064379455661 0.491076535596019 GVINP1 other 1 1 1 -0.778422839189255 0.689064379455661 5.03876380169485e-10 16.1216056483148 2.97621643587892 5.41681224993097 9.11610755463451e-08 -35.5652121230862 15.5888959030894 -2.28144522512579 0.0229069473044049 NPIPA2 other 4.19477086491096e-06 1 0.000933762896821213 5.41681224993097 -2.28144522512579 3.06082454626474e-23 73.8082649668042 8.2544795452854 8.941601291987 5.92368779854655e-18 -99.7483580252791 30.6744647271164 -3.25183695665604 0.00121738095484441 MPV17L2 other 3.84898686692791e-19 1 7.96143640124656e-14 8.941601291987 -3.25183695665604 7.55101328829529e-11 3.15444255878248 2.99340899078294 1.05379604607836 0.29244498123577 -37.033018970555 6.30839674481224 -5.87043276899308 7.57223516562887e-09 TMEM9B-AS1 other 6.55729993955563e-07 0.000103913783177925 1 1.05379604607836 -5.87043276899308 3.59317455072899e-14 333.394227433563 72.8044995039137 4.57930800575918 5.78329941670445e-06 -1246.01923058302 258.077905113273 -4.82807402685686 1.79241712235489e-06 ATP6V1G2-DDX39B other 3.59604909036957e-10 0.0224948348855539 0.0530328556511798 4.57930800575918 -4.82807402685686 1.16793074749881e-07 36.4368660604748 10.4910770567493 3.4731291995452 0.000556485431832561 -114.202981746254 34.1779248661924 -3.3414252677236 0.000892272747743444 BORCS8 other 0.000840676552049645 1 1 3.4731291995452 -3.3414252677236 0.191996872634247 14.1115943219382 7.75871662847269 1.81880522226471 0.0694918424162543 10.8470109955537 32.5259744576983 0.333487656447029 0.738894941018809 INMT-MINDY4 other 1 1 1 1.81880522226471 0.333487656447029 8.96182496034356e-30 462.543217727897 41.1918862160467 11.2289885270587 2.37127520481936e-26 -285.53031666358 141.614977461169 -2.01624377436964 0.0442871820272983 DPP3 other 1.22418528958293e-25 1 3.42341001319772e-22 11.2289885270587 -2.01624377436964 1.02294075871722e-44 299.849906354003 19.1056924330863 15.694270563821 6.80388308815842e-46 241.777196717122 182.257597853298 1.32656854674301 0.185220600134201 STX16-NPEPL1 other 1.52592072977848e-40 1 1.03766020977504e-41 15.694270563821 1.32656854674301 9.07512145914894e-29 386.708728408113 87.3745665781446 4.42587292335527 1.16102851859447e-05 -1859.10944446339 207.758011953528 -8.94843682312113 5.66437419695236e-18 ANKHD1-EIF4EBP3 other 1.22768243099367e-24 8.65912883488107e-14 0.104086206691995 4.42587292335527 -8.94843682312113 2.41071978597398e-60 1258.7944746579 67.8357645753477 18.5565016114724 5.78782108945818e-60 -229.516578092297 207.434502153729 -1.10645324528609 0.269017639848327 BRK1 other 3.7057584549992e-56 1 8.94334114743079e-56 18.5565016114724 -1.10645324528609 0.610534296799578 156.133968654983 295.080549042796 0.529123214530614 0.596934235614397 -441.461465107564 737.271597166157 -0.598777257667873 0.549568856033428 SAA2-SAA4 other 1 1 1 0.529123214530614 -0.598777257667873 4.55050418338142e-15 61.1004376533621 8.40589068478501 7.2687642445739 1.25714881752608e-12 -29.1135342935094 20.7009349165389 -1.40638741249552 0.160175913454156 PIGY other 4.70795162812642e-11 1 1.52504723054088e-08 7.2687642445739 -1.40638741249552 1.77550011595786e-28 306.843187445738 39.3733690960734 7.79316564698901 3.44560919023025e-14 -459.47020591352 91.2733409998732 -5.03400227142073 6.58102184105849e-07 CHMP1B other 2.39372925633438e-24 0.00842502416092307 4.33871109233793e-10 7.79316564698901 -5.03400227142073 0.00608886044112904 1.05344950135752 0.856130127448074 1.23047825042392 0.219052805859261 -4.30205455743758 1.79298614842422 -2.39937969471682 0.0167601114789953 STX17-AS1 other 1 1 1 1.23047825042392 -2.39937969471682 0.0846539350155274 0.880528999520112 1.65430581430608 0.532264948781226 0.594759025728608 -7.48062728826079 3.97340008360304 -1.88267658198604 0.0602756511663618 EID3 other 1 1 1 0.532264948781226 -1.88267658198604 2.0539988599558e-11 58.220577434675 9.19519439424601 6.33163095182709 5.09441505617396e-10 -40.6049323905272 32.0198289968031 -1.26811833987562 0.20530014008899 MSH5-SAPCD1 other 1.83381018216854e-07 1 5.73529247024064e-06 6.33163095182709 -1.26811833987562 3.19283661709956e-05 -1.64726671958357 2.27941020701245 -0.722672345028494 0.470191202443986 -19.4753937517635 4.51685528454136 -4.31171523657548 1.9229530109463e-05 TOLLIP-AS1 other 0.18470559829921 0.228081456628341 1 -0.722672345028494 -4.31171523657548 1.16940249884712e-22 27.5710779905289 7.30689226747917 3.77329745413651 0.000178761938497436 -94.2099798880777 13.8180871044866 -6.81787422352321 2.45869439468349e-11 HTD2 other 1.45742633431316e-18 3.54937122816509e-07 1 3.77329745413651 -6.81787422352321 0.000717280897074448 47.5432570491708 15.2559703371643 3.11637057482691 0.00192811095501939 121.222361445722 33.2062556165719 3.65058809537156 0.000287034861356873 PDXDC2P other 1 1 1 3.11637057482691 3.65058809537156 8.91840544068032e-05 24.8568324489202 6.0109055491283 4.13528914167099 4.1078285298413e-05 2.12350330441148 27.4911220705264 0.0772432387068012 0.938458550342378 SNHG9 other 0.487569225441993 1 0.351671200439714 4.13528914167099 0.0772432387068012 0.0645704514848277 1.289653182792 0.90179451014687 1.43009651121292 0.153286439467053 -2.63832174863551 2.21462222009504 -1.19131909934611 0.234068692138383 PGAM1P8 other 1 1 1 1.43009651121292 -1.19131909934611 0.0740840878843141 10.0553295169921 9.26124875193374 1.08574229958919 0.278072146073258 39.4955995991542 17.3843602172952 2.27190411988018 0.0234804575756195 FXYD6-FXYD2 other 1 1 1 1.08574229958919 2.27190411988018 0.155346490584544 2.1052777519746 20.3211142831204 0.103600507464462 0.917524426179706 -54.5891655279998 36.4902634892437 -1.49599263770982 0.135233348434442 MIR100HG other 1 1 1 0.103600507464462 -1.49599263770982 4.21041759778322e-11 6.7043279485541 1.1062362935499 6.06048453449305 2.53441117510436e-09 -10.7312059534937 5.79427027432438 -1.85203752076356 0.0645610084011486 ABCC6P2 other 3.7039043607699e-07 1 2.77467335450426e-05 6.06048453449305 -1.85203752076356 0.45300979767744 14.2406973051152 11.5211827791296 1.23604473413198 0.216976358260411 11.3661602624153 23.2472728314662 0.488924457712335 0.625092593951783 WTAPP1 other 1 1 1 1.23604473413198 0.488924457712335 2.31737435843273e-32 242.015288163657 106.539740411784 2.27159637547689 0.0235079324324169 -1928.82558921673 186.547145115118 -10.3396146214216 5.78142241638146e-23 EID1 other 3.23945761565311e-28 8.97334573246567e-19 1 2.27159637547689 -10.3396146214216 0.141484857322996 14.8765260515166 14.6289485566462 1.01692380651362 0.309642560841713 -42.6774549257887 31.9571645130356 -1.33545812264978 0.182285974601924 NOX5 other 1 1 1 1.01692380651362 -1.33545812264978 0.103899216991285 5.06015946569773 3.12845553445433 1.61746248587175 0.106360286016614 -5.92291603195084 6.93892683103207 -0.853578107418938 0.393715867465799 HCAR3 other 1 1 1 1.61746248587175 -0.853578107418938 0.242877425005392 -3.63839700179273 3.12789825641226 -1.16320823234385 0.245258772621445 -10.497438996397 6.91419742900703 -1.51824403398683 0.12953810796054 TBX5-AS1 other 1 1 1 -1.16320823234385 -1.51824403398683 5.81576252307022e-05 24.1826832719256 37.9258669272616 0.637630336000118 0.523998273805311 -402.380898295119 102.292716071824 -3.93362219468875 9.51660217948211e-05 PCDHA3 other 0.325915331792855 1 1 0.637630336000118 -3.93362219468875 1.6270508036693e-08 0.728695875782902 0.758861501151908 0.96024883944802 0.337356586219863 -7.47834519171983 1.49567473025101 -4.99998097210935 7.74598320735238e-07 EBLN2 other 0.000124257869876224 0.00988852216250605 1 0.96024883944802 -4.99998097210935 1.35629907454359e-06 2.84161314686005 0.686090761254589 4.14174524324429 4.0127409791442e-05 -8.95132253851133 4.24874472293351 -2.10681580613555 0.0356046795136589 NPIPB8 other 0.00895293019106223 1 0.343851774502867 4.14174524324429 -2.10681580613555 3.40798251743452e-42 285.600550651456 25.1254073158137 11.3670018185815 5.66417990978881e-27 -464.803705372724 71.8952501265287 -6.46501270326919 2.28131092087198e-10 NEDD8-MDP1 other 5.03733895901997e-38 3.24014590091448e-06 8.20399818133812e-23 11.3670018185815 -6.46501270326919 1.06193896322346e-20 47.5312687110062 24.5115892439313 1.93913451461635 0.0530035948995353 -383.112839918633 45.4797993600609 -8.42380233222999 3.28596363049985e-16 POLR2M other 1.27496391924608e-16 4.97429174385067e-12 1 1.93913451461635 -8.42380233222999 1.12954875882912e-22 3.11601823588879 0.304034426730733 10.2488993414173 2.06834050546743e-22 -2.58443259035338 2.08257580668217 -1.24097887916538 0.215223519966279 ZNF252P-AS1 other 1.40832139250814e-18 1 2.90498423992901e-18 10.2488993414173 -1.24097887916538 3.18209212494458e-39 -8.65920488735423 5.37674097637286 -1.61049321985299 0.107871346566604 -126.715654947982 9.90588559997791 -12.7919562233047 6.18315301763366e-33 FDXACB1 other 4.64330882871913e-35 9.68529088682137e-29 1 -1.61049321985299 -12.7919562233047 2.73105825376863e-06 172.863426532532 44.6541989298587 3.87115726348736 0.000121604483331295 -453.223575737678 180.694168576896 -2.50823576270977 0.0124262037780662 TRIL other 0.017517007639672 1 0.99618392744997 3.87115726348736 -2.50823576270977 1.35104869746836e-08 167.387860956192 44.7132163108232 3.74358802087951 0.000201527698657034 -339.803551801379 115.360902100684 -2.94556947469783 0.00336719960124199 SNHG1 other 0.00010355788266095 1 1 3.74358802087951 -2.94556947469783 0.127408651835445 14.0698410258958 12.8903253047506 1.09150395302363 0.275558613926928 -51.3174961917632 36.852147191853 -1.39252391250375 0.164361241954457 AGAP2-AS1 other 1 1 1 1.09150395302363 -1.39252391250375 0.0637110982980723 9.74527939741019 4.31725801381533 2.25728445374936 0.0243853454803105 19.7021042174394 15.4845302505942 1.27237338805827 0.203783064602018 KLRC4 other 1 1 1 2.25728445374936 1.27237338805827 0.000161789818410027 -5.7096881071832 2.83063124820106 -2.01710770726913 0.0441749635200723 17.7536278746049 6.53788434956473 2.71550044714187 0.00682790672409395 TIFAB other 0.855706349570633 1 1 -2.01710770726913 2.71550044714187 6.70897595099489e-12 5.48802889831339 0.956694387281429 5.73644935234578 1.62981936280269e-08 -9.28931600749579 2.92206571242239 -3.1790236502912 0.00156435801145787 TMEM5-AS1 other 6.13468760958973e-08 1 0.00017297272897425 5.73644935234578 -3.1790236502912 9.27001870322252e-15 175.167453548571 26.9889686373173 6.49033521445383 1.93021506312171e-10 -181.243112288402 60.7590894865128 -2.98297939979226 0.00298260472567934 PXN-AS1 other 9.47952112591534e-11 1 2.2034441277275e-06 6.49033521445383 -2.98297939979226 2.68490379090961e-05 4.39465640108669 1.0422202596891 4.21662922038922 2.92675416516235e-05 13.5402983675159 5.23524732161734 2.58637224484228 0.00997087858303178 DENND5B-AS1 other 0.15652989101003 1 0.254130064161047 4.21662922038922 2.58637224484228 7.08248309801988e-14 59.3674787856015 7.4524252776863 7.96619577835378 9.54965389289333e-15 27.4514103993957 21.4530488069778 1.27960415539944 0.201226859969059 LINC00346 other 7.00953352211028e-10 1 1.21605292672104e-10 7.96619577835378 1.27960415539944 0.293301599571287 389.868853592412 335.446096848218 1.16223994631489 0.24564670910726 -849.724865789392 1271.60115672268 -0.668232221476901 0.504268268540721 CYP2A6 other 1 1 1 1.16223994631489 -0.668232221476901 0.00292300312968759 -2.93994410157116 3.30158488237757 -0.890464490936856 0.373615292370245 -22.1596048829389 7.04492495409474 -3.14547067957893 0.0017500284011029 MT1JP other 1 1 1 -0.890464490936856 -3.14547067957893 0.574398329737362 -0.558060181693368 2.83324114482023 -0.196968825867019 0.843925907853397 5.74939156222849 6.20804972865961 0.926118799546062 0.354797185957597 PAPPA-AS1 other 1 1 1 -0.196968825867019 0.926118799546062 3.70791976365249e-16 -3.73082219032986 42.4094647224079 -0.0879714520036986 0.929931799278327 -767.916613454031 94.8148599681857 -8.09911667550529 3.66916965250255e-15 CTSO other 3.97229444280091e-12 5.51659657253758e-11 1 -0.0879714520036986 -8.09911667550529 3.58514544788907e-17 119.514640468072 16.196457862051 7.37906037764591 5.99867306298743e-13 -60.7582057815556 33.5679615381308 -1.81000582095337 0.0708465738124786 APOPT1 other 3.95835908901432e-13 1 7.32677927913285e-09 7.37906037764591 -1.81000582095337 6.47650388045557e-63 68.7402918411728 3.57795013620504 19.2121995065259 3.16737820055331e-63 6.28592725854018 18.0191790658086 0.348846483826099 0.727339044840995 TRAPPC2B other 9.98029247978203e-59 1 4.90151776535625e-59 19.2121995065259 0.348846483826099 5.97659950480326e-19 4.41771492434233 5.49931569079858 0.803320844397789 0.422142108832814 -86.4342475848387 10.3096035680039 -8.38385753775147 4.45671504955625e-16 DNAAF4 other 6.89819114844392e-15 6.7430098699786e-12 1 0.803320844397789 -8.38385753775147 2.44090079932375e-07 8.66801477223764 1.56430590442935 5.54112513907545 4.68100239455956e-08 4.29863569307911 5.19193383285061 0.827945006902941 0.408063379872289 A2MP1 other 0.00171497690160487 1 0.000486964679106031 5.54112513907545 0.827945006902941 1.35703085134898e-19 42.2528130184078 4.52117273211142 9.34554274343671 2.39626022462916e-19 -6.27597727581625 13.9179723148032 -0.450926121554437 0.652223807276962 URB1-AS1 other 1.59383273490938e-15 1 3.27209333673111e-15 9.34554274343671 -0.450926121554437 4.25403156628917e-13 73.2547623488201 9.78113912531762 7.48938967233444 2.83283659668298e-13 -26.4069327279758 41.3107868938882 -0.639226088716375 0.522946418376349 ZNF432 other 4.07366062787851e-09 1 3.49232095639078e-09 7.48938967233444 -0.639226088716375 4.48889457496324e-07 9.61790419507093 4.7811259848741 2.01163998302885 0.0447732754004654 87.5138245079141 16.2928731234737 5.3712947891204 1.18098235643027e-07 LINC01152 other 0.00308746168865972 0.00155925100519488 1 2.01163998302885 5.3712947891204 0.939831507989196 0.0429762330618012 0.446777694018902 0.0961915369480889 0.923403942266225 -0.487381624509625 1.61976105817906 -0.30089723545863 0.763608037112438 CCND2-AS1 other 1 1 1 0.0961915369480889 -0.30089723545863 0.000343652866317511 6.21150921621717 8.4422696511201 0.735762949172446 0.462203555207174 -71.6907516991206 20.214055483685 -3.54657934707773 0.000425192054260289 ZNF10 other 1 1 1 0.735762949172446 -3.54657934707773 4.78884424798674e-06 228.981366055264 46.9180152401704 4.88045721634052 1.3974894243335e-06 79.7437820934664 159.965120742654 0.498507310363958 0.618330635710082 ZNF486 other 0.029954220771157 1 0.0133236641715956 4.88045721634052 0.498507310363958 0.00019138434976267 32.9420905182735 23.114459733451 1.425172420128 0.154678741551528 -174.158636644917 54.5173247707965 -3.19455581096689 0.00148128871036044 SMIM3 other 1 1 1 1.425172420128 -3.19455581096689 1.10597757023246e-28 112.533703158769 16.3980289134366 6.86263597611775 1.87016216746645e-11 -130.45745247532 30.4716503332633 -4.28127295530529 2.20129171332752e-05 HMBS other 1.49450749065512e-24 0.260148654681047 2.20024579002427e-07 6.86263597611775 -4.28127295530529 4.97764831384308e-18 13.1710209445468 3.36105562659781 3.91871554886433 0.000100328282942864 -78.2792776294817 11.3968032476445 -6.86852935235682 1.77205508185543e-11 ZNF225 other 5.61976494632883e-14 2.56363208692025e-07 0.829112930239825 3.91871554886433 -6.86852935235682 4.14175112500477e-05 5.90689743348531 1.49136775072051 3.96072493228553 8.47773657474781e-05 -7.90178177703574 7.82595631097177 -1.00968897129641 0.313098211602815 ABCC6P1 other 0.236908164350273 1 0.705420266702368 3.96072493228553 -1.00968897129641 8.71298610143202e-26 26.5351527844968 4.23827609230989 6.26083629441775 7.82445435910143e-10 -66.7828944085401 10.0610804952907 -6.63774576098452 7.7799644696531e-11 DND1 other 1.13861302373514e-21 1.11385751312023e-06 8.74695752803949e-06 6.26083629441775 -6.63774576098452 1.21374738096216e-58 45.5695410848459 2.64061969779703 17.2571389673655 4.4923648799118e-53 -42.8685167374555 11.4100597760481 -3.75708081980821 0.00019139531824747 POLG2 essential 1.86140298344357e-54 1 6.9070110028644e-49 17.2571389673655 -3.75708081980821 3.9562868459953e-53 268.795807414771 16.733849139921 16.06299932354 8.37684129725086e-48 -81.1219848228043 60.4612930689368 -1.34171766274186 0.180247338954355 SMIM10L1 other 6.01711666407425e-49 1 1.28031642387182e-43 16.06299932354 -1.34171766274186 0.000117686351552573 -3.03354588026148 1.98284550440924 -1.52989523062478 0.126629312006174 -20.054616657296 4.68164123534612 -4.28367225277427 2.17711262337906e-05 LINC02361 other 0.633741003110608 0.257400025462106 1 -1.52989523062478 -4.28367225277427 0.0297644160998391 -67.5047628593427 454.140336010895 -0.148642957928589 0.881890355917902 -4025.3651987959 1567.41747914118 -2.56815127581803 0.0104895554230671 CYP2B7P other 1 1 1 -0.148642957928589 -2.56815127581803 0.914336900582026 -36.3357621084279 91.9380500629811 -0.39522006485385 0.692838311182741 -11.9043530035373 247.095174690201 -0.0481771973834071 0.961593035728288 MTRNR2L1 other 1 1 1 -0.39522006485385 -0.0481771973834071 4.1680607029224e-14 17.6207246972145 2.68681506779183 6.55822014266736 1.27969774055033e-10 -36.6723438456575 9.4382993658545 -3.8854821641205 0.000114861155853013 ZBTB11-AS1 other 4.1572237450948e-10 1 1.46986082479611e-06 6.55822014266736 -3.8854821641205 5.20895340265479e-10 81.9400605301718 12.3591882463941 6.62989015917599 8.1344080027068e-11 20.3731803702468 52.4392116827211 0.388510424098533 0.697790903477186 ZNF350 other 4.33437012634905e-06 1 9.39442780232608e-07 6.62989015917599 0.388510424098533 0.000433977285276231 3.78039236420984 1.27519429139509 2.96456186301932 0.00316450907875271 -6.06951805010473 4.00481800282598 -1.51555402663038 0.130215120085633 PLBD1-AS1 other 1 1 1 2.96456186301932 -1.51555402663038 1.1002994569505e-06 29.6295785801368 10.3256596221026 2.86950951944156 0.00427300535255553 -116.886160632646 35.1060623388828 -3.3295149853131 0.000929692006814614 ZNF253 other 0.00731259019089304 1 1 2.86950951944156 -3.3295149853131 0.205184493823178 -58.100705164531 54.2052075921073 -1.07186574400263 0.284258252497084 -220.653036823903 131.866890294706 -1.67330128382319 0.0948460705988566 SLC5A8 other 1 1 1 -1.07186574400263 -1.67330128382319 0.245698240467231 -635.716144679824 757.409482464617 -0.83932952966366 0.401652424936364 -2839.14833458799 1700.43180998809 -1.66966315138969 0.0955602539148543 HP other 1 1 1 -0.83932952966366 -1.66966315138969 9.85824605394929e-07 5.79354884385693 4.43611252109552 1.30599681958162 0.192109688519913 -69.8871846829815 15.3640584673833 -4.54874503578248 6.6694290747379e-06 MIR200CHG other 0.00658037924101115 0.0813870429990266 1 1.30599681958162 -4.54874503578248 5.7898919468583e-07 125.143625382617 50.0359706063698 2.50107320525698 0.0126746268368274 -637.804164937938 168.43806575657 -3.78657972634111 0.000169740679730445 KIAA1147 other 0.00394627002939362 1 1 2.50107320525698 -3.78657972634111 7.59396794072233e-38 958.316352174865 72.2061098857073 13.2719565379128 5.03495240405145e-35 -555.818741111175 323.893887166387 -1.71605196372739 0.0867218587775571 LSM14A other 1.10120129108415e-33 1 7.52322588213368e-31 13.2719565379128 -1.71605196372739 1.51543570583977e-07 35.0553397214996 8.50499803857575 4.12173401598691 4.36103898446644e-05 -84.7147326217309 37.4692531169056 -2.26091329756207 0.0241677752085158 NHLRC4 other 0.00108323344253426 1 0.372519950053124 4.12173401598691 -2.26091329756207 1.7273182685136e-06 35.8563159149356 6.87702312919232 5.21392981255638 2.63579924513751e-07 28.5078660625591 17.5663566199096 1.62286731844261 0.105200306878431 TMPO-AS1 other 0.0112932068395419 1 0.00262841900725113 5.21392981255638 1.62286731844261 2.35445623672035e-35 450.949263069613 48.3015453049893 9.33612496706255 2.53148868178691e-19 -719.140571588818 108.577088960956 -6.62331785159041 8.45020158214073e-11 GATC other 3.36899142912315e-31 1.20956185446762e-06 3.45624149724367e-15 9.33612496706255 -6.62331785159041 0.186148670122098 -0.766904477932437 1.21858487003018 -0.629340226350785 0.529395988912515 -6.11140579975102 3.33997404972492 -1.82977643202179 0.0678417600691521 LINC01619 other 1 1 1 -0.629340226350785 -1.82977643202179 4.54969062365946e-35 130.257060273358 17.503810152216 7.44164037090336 3.93552949494286e-13 -290.750560345848 38.0080116234598 -7.64971772862717 9.28142315445609e-14 ZNF271P other 6.49468336527388e-31 1.37940510921526e-09 4.8285011373454e-09 7.44164037090336 -7.64971772862717 9.2473255732881e-10 136.004179837792 20.7561446933963 6.55247792144477 1.32412833430449e-10 -127.345894034436 173.976541556547 -0.731971637641992 0.464504015703902 ZBED6 other 7.58188223753891e-06 1 1.52009932778156e-06 6.55247792144477 -0.731971637641992 0.189964011363556 -25.2574532578858 30.5886310275197 -0.825713750810306 0.409327125655877 -188.095083892419 104.173355190384 -1.80559686830343 0.071531982135261 MGAM other 1 1 1 -0.825713750810306 -1.80559686830343 7.22981995936996e-41 52.3138293750788 13.8712524429454 3.77138471023101 0.000180376690592981 -315.475319249008 27.5510433546729 -11.4505761247514 2.58541875975481e-27 FNTB other 1.0626389376282e-36 4.03661430960519e-23 1 3.77138471023101 -11.4505761247514 1.10201569150665e-19 16.3520671512481 2.60375556611323 6.28018519252088 7.10764652426355e-10 -52.186810251918 9.37505189177445 -5.56656228193318 4.15347336174717e-08 ZNF625 other 1.29718267047247e-15 0.000556690034674973 7.95701028391304e-06 6.28018519252088 -5.56656228193318 3.16350700719946e-08 32.5972563875622 24.7174542662207 1.31879505213084 0.187806112345 -348.983521236965 66.0807940636015 -5.28116415945419 1.87543818202147e-07 GALNT4 other 0.000237389565820248 0.00245063507244746 1 1.31879505213084 -5.28116415945419 2.67138442848812e-31 24.7158330006742 21.2130748818652 1.16512260190075 0.244479069923336 -506.856362277344 44.6756057551777 -11.3452599849438 6.27997665027242e-27 PSMA3-AS1 other 3.70093598722744e-27 9.80115955808017e-23 1 1.16512260190075 -11.3452599849438 0.269914778768771 6.85499367948558 140.171504195627 0.0489043312963137 0.961013420639891 670.46998913415 427.181093946389 1.5695216821049 0.117105743609303 KRT7-AS other 1 1 1 0.0489043312963137 1.5695216821049 0.00796275888323974 17.9298516357944 13.2137284394299 1.35691086115343 0.1753764587191 -116.706676881799 45.2097846398632 -2.58144730861854 0.010101186638308 LBX2-AS1 other 1 1 1 1.35691086115343 -2.58144730861854 0.00238924877507071 -0.772896608183892 12.8356498223555 -0.0602148406103878 0.952006478767739 -122.758709985014 37.0187580444984 -3.31612178445999 0.000973200911574095 INAFM1 other 1 1 1 -0.0602148406103878 -3.31612178445999 7.7938243381854e-09 251.169649734731 49.5705998031074 5.06690761726442 5.56722594724155e-07 -316.934508985129 146.284056838623 -2.16656904268633 0.03070601465345 CNPY2 other 6.07294792431407e-05 1 0.00543998389175662 5.06690761726442 -2.16656904268633 0.27203585199509 17.0458228811765 25.0132994992861 0.68147038665023 0.495862835542161 136.197522949075 84.8509492727391 1.60513847065271 0.109041535072215 MGAM2 other 1 1 1 0.68147038665023 1.60513847065271 7.94274921170006e-50 16.9867711998527 1.01229913043999 16.7803870309258 5.34616711034995e-51 6.88380049553248 7.46578205836485 0.922046805239875 0.356923692485119 LINC01481 other 1.20062597084058e-45 1 8.2020895806989e-47 16.7803870309258 0.922046805239875 3.67485802284819e-08 237.902498189568 77.6890461636397 3.06223991588806 0.00230589781808038 -877.666529326218 225.231011015283 -3.89673928723192 0.000109698938058283 CUX1 other 0.000274658888627674 1 1 3.06223991588806 -3.89673928723192 3.60799917202725e-12 53.2786212071357 7.49367634278265 7.1098108284927 3.6709531305991e-12 -20.1031368330315 26.3227309035811 -0.763717750512602 0.445366554426643 TEN1 essential 3.33487363470479e-08 1 4.40734632859728e-08 7.1098108284927 -0.763717750512602 6.57449812921836e-10 378.273067907662 70.8270624453467 5.34079848644796 1.35831864769711e-07 -187.218439029375 130.884403226975 -1.43041060977073 0.153169131079572 P2RX5-TAX1BP3 other 5.43316525398605e-06 1 0.00137611262198194 5.34079848644796 -1.43041060977073 6.35344407085477e-20 18.7152074496429 3.6134650342298 5.17929667849463 3.14726136595887e-07 -69.6232917448135 10.5730292878701 -6.58498996353759 1.07853117997045e-10 BCDIN3D-AS1 other 7.51265002016986e-16 1.54078964370578e-06 0.00312523053639716 5.17929667849463 -6.58498996353759 0.000379707509238608 24.0430667738936 9.13651642164985 2.63153544133312 0.00874252861143222 73.8198525873337 20.074042240629 3.6773785619483 0.00025917487881813 MAP1LC3B2 other 1 1 1 2.63153544133312 3.6773785619483 0.521009878175809 -12.7577074881011 12.2804076977403 -1.038866770722 0.299326529065703 5.16078932299772 41.7236014687131 0.123689929472354 0.901606304565431 CLEC5A other 1 1 1 -1.038866770722 0.123689929472354 5.53285302737824e-29 107.047058442563 38.0220439759695 2.81539463028917 0.00505000884948593 -719.808168214414 75.3444298098234 -9.55356845929127 4.38069736038585e-20 CHURC1 other 7.50144213451941e-25 6.74802621393836e-16 1 2.81539463028917 -9.55356845929127 2.21040583524693e-11 21.0458637895888 14.3863550203372 1.46290452027893 0.144069946616591 -172.63932706345 30.1226966132161 -5.73120425704869 1.65197796946018e-08 VASH1-AS1 other 1.97013472095559e-07 0.000224305568693304 1 1.46290452027893 -5.73120425704869 2.13359021010046e-19 305.487594862275 40.5522198307796 7.53319044276845 2.06153015152237e-13 -176.79280688729 73.9938344370141 -2.38929105691612 0.0172187020420277 C17orf49 other 2.4956604687545e-15 1 2.54949433838771e-09 7.53319044276845 -2.38929105691612 8.14763579189981e-50 10.4375483031564 0.698588610983162 14.9409081955502 1.89250825070643e-42 -11.6559945935564 3.04658327459686 -3.82592351594224 0.000145624815384281 ITFG2-AS1 other 1.23143367358774e-45 1 2.87244902292222e-38 14.9409081955502 -3.82592351594224 4.96961765008586e-27 109.881407894875 9.51078208191989 11.5533514434907 1.38129756713259e-27 -32.8977605648092 73.9713965273005 -0.444736237373424 0.65669905488537 RTEL1 other 6.59716743048898e-23 1 2.00730162455708e-23 11.5533514434907 -0.444736237373424 5.30308267049452e-15 129.071844477836 23.237347886367 5.55449981250055 4.36801016826513e-08 -331.670411200369 80.8565828707834 -4.10195928920729 4.72608392843179e-05 PPT2-EGFL8 other 5.4743722407515e-11 0.546382562965999 0.000454797218719766 5.55449981250055 -4.10195928920729 0.00138178755330067 -2.00803386270956 1.47698140232765 -1.35955257090238 0.174536885677724 -11.1273135508858 3.04772254341846 -3.65102577165864 0.000286509695558656 MEG8 other 1 1 1 -1.35955257090238 -3.65102577165864 0.00420368943815044 2.609497697173 0.797207438255398 3.27329823073855 0.00113038354999956 -0.30570843932391 3.45229479049514 -0.0885522407198789 0.929470294398449 ZNF578 other 1 1 1 3.27329823073855 -0.0885522407198789 3.98047722109988e-52 98.858725675643 9.78614928553819 10.1019024737069 4.21142408389476e-22 -110.213998500072 21.4842771668844 -5.1299840177986 4.03957288278115e-07 PDF other 6.04276246935173e-48 0.0052126648479408 5.89936285671977e-18 10.1019024737069 -5.1299840177986 0.000255607377524003 9.76994536960657 6.60661301205159 1.47881302443242 0.139766959132959 -56.5343793100875 18.2268662581631 -3.10170593832979 0.00202350829968818 LINC00641 other 1 1 1 1.47881302443242 -3.10170593832979 0.582149090167836 -5.04216255154043 7.93688090095039 -0.6352826273274 0.525511714696286 -16.7913737023763 17.2576891863892 -0.972979262809956 0.330996833342727 SPESP1 other 1 1 1 -0.6352826273274 -0.972979262809956 0.00338836368657268 -6.54859653509353 4.01565878046731 -1.63076518526593 0.103520794474926 -28.0524656583594 8.32779863015569 -3.36853313873116 0.000809408502028983 MIR1247 other 1 1 1 -1.63076518526593 -3.36853313873116 1.6283480460754e-13 277.90043267874 73.47418374356 3.78228676413296 0.00017255354691237 -686.738311865758 162.871690838885 -4.21643754251369 2.90488583814108e-05 SPECC1L-ADORA2A other 1.5894305277742e-09 0.340220229363084 1 3.78228676413296 -4.21643754251369 9.76410234135605e-15 24.3103856237289 11.6371199918411 2.08903797853534 0.0371650394436118 -171.037659305619 25.9857582202346 -6.58197686040331 1.08752143859139e-10 TRIM6-TRIM34 other 9.97695977239761e-11 1.5535243750278e-06 1 2.08903797853534 -6.58197686040331 2.37683670956212e-25 207.93978242252 20.1105445669923 10.3398384727888 5.45954550605174e-23 -81.8936942905464 66.7982925570807 -1.225984844157 0.220737761180232 BCL2L2-PABPN1 other 3.08560941635354e-21 1 7.70833229999445e-19 10.3398384727888 -1.225984844157 2.20263319767868e-44 210.214689604036 22.9683263793605 9.15237297363279 1.12867577053182e-18 -319.759863984357 44.8178984525689 -7.13464653686878 3.12565021176617e-12 SYNJ2BP-COX16 other 3.28170320122147e-40 4.56813778449626e-08 1.52980713937883e-14 9.15237297363279 -7.13464653686878 0.00917954266282192 2.63411018570437 2.79470322796706 0.942536638360879 0.346344170702003 -18.9071262693743 7.2041249625083 -2.62448616143817 0.00892644327954054 LINC00930 other 1 1 1 0.942536638360879 -2.62448616143817 2.03241894503265e-16 31.8972436117724 9.86341725539207 3.23389376986308 0.00129467919251985 -138.610966537556 22.0250694504833 -6.29332710387953 6.36731439657582e-10 TRIM34 other 2.19501246063526e-12 8.96199501318046e-06 1 3.23389376986308 -6.29332710387953 2.01153970106898e-13 16.2020456900298 2.75392102388985 5.88326446164559 7.09703999109179e-09 -14.5282615422629 5.75097200353034 -2.52622713748988 0.0118168737403508 LINC00638 other 1.95602120531948e-09 1 7.64422177440496e-05 5.88326446164559 -2.52622713748988 1.5425445543115e-21 4.3887296363862 2.58276339860774 1.69923797075333 0.0898556754053736 -59.880156156181 6.58331022248034 -9.09575185317949 1.83873202246854e-18 SLC25A21-AS1 other 1.88267562853719e-17 2.81712133162404e-14 1 1.69923797075333 -9.09575185317949 3.42841896448043e-22 125.440035222462 12.8002571298264 9.79980589063078 5.70669874653869e-21 193.465732197276 32.6872084446001 5.91869851857099 5.7889416604753e-09 PRC1-AS1 other 4.23855436578716e-18 7.96500483064796e-05 7.91861518069708e-17 9.79980589063078 5.91869851857099 0.000131570250700796 9.45493936445137 2.23598431755575 4.2285356342691 2.76411914643294e-05 9.93076585982663 4.65997242316242 2.13107824640028 0.0335354065125804 HIF1A-AS1 other 0.704821833004165 1 0.240257236207951 4.2285356342691 2.13107824640028 2.55324000372989e-20 -87.0399907080055 68.2087985797186 -1.27608156895299 0.202468250417909 -1846.39870263474 190.361077452115 -9.69945499021034 1.24198949633895e-20 RNASE4 other 3.04269611244491e-16 1.91688658864953e-16 1 -1.27608156895299 -9.69945499021034 2.12349914274714e-14 50.4349069857433 13.0565675373772 3.86279983934236 0.000126076070898798 -89.8297863746051 28.291679403881 -3.1751309313325 0.00158543153168889 MC1R other 2.14197358528904e-10 1 1 3.86279983934236 -3.1751309313325 5.80382982785456e-17 -16.8054142235107 4.61859083697027 -3.63864538269747 0.00030004362393765 -85.1043854175177 9.51032266141813 -8.94863281166818 5.57810480636771e-18 TGFB3-AS1 other 6.36680132115645e-13 8.52780662797496e-14 1 -3.63864538269747 -8.94863281166818 6.9122741071491e-46 160.493748030244 10.1125919893139 15.8706836189811 1.57909699019726e-46 45.3271944746774 43.3796658597342 1.04489496579435 0.296557934024475 CEP95 other 1.03476743384022e-41 1 2.41049155553612e-42 15.8706836189811 1.04489496579435 3.95391730911362e-07 16.8283723851419 6.52355370962249 2.57963268706126 0.0101522881171511 86.1703383398876 16.0528916258301 5.36790133194658 1.1821316711109e-07 LINC01956 other 0.00273334303579025 0.00156065023220061 1 2.57963268706126 5.36790133194658 0.00138278235439031 9.08297061963305 2.92459544751905 3.10571864814266 0.00199709416816098 -2.94327235731587 5.90318102929329 -0.498590902550761 0.618269146305959 FOXN3-AS1 other 1 1 1 3.10571864814266 -0.498590902550761 1.93181082055235e-10 457.927861944494 175.434511382333 2.61024959306045 0.00930553070677673 -1242.25853592725 380.141023909759 -3.26788864603613 0.00115429512000624 TUBB3 other 1.64628918127471e-06 1 1 2.61024959306045 -3.26788864603613 1.84846599061522e-12 99.725852998367 21.7230026192153 4.59079505473858 5.4851316619119e-06 -163.015701965787 41.9985858215722 -3.88145692948679 0.000116529810816854 UBE2F-SCLY other 1.72887024102241e-08 1 0.0503758455084329 4.59079505473858 -3.88145692948679 0.168473213618978 7.14157366684747 9.80354259960763 0.728468672858452 0.466645471127447 38.6445178244683 20.4426328848843 1.89038848577293 0.0592462006136715 TMEM179 other 1 1 1 0.728468672858452 1.89038848577293 2.46202191108984e-29 17.9136977409499 12.0621771513024 1.48511313639725 0.138096293610173 -221.594780977142 21.8998991496175 -10.1185297458784 3.70397895718395e-22 TVP23C-CDRT4 other 3.34810359689107e-25 5.74005618994797e-18 1 1.48511313639725 -10.1185297458784 0.00153715469004719 -4.8429373123649 4.96018305609494 -0.976362617588081 0.329320368805603 -35.9157413289976 9.96346654107103 -3.60474350778889 0.000341280800905225 FPGT-TNNI3K other 1 1 1 -0.976362617588081 -3.60474350778889 4.36421986751982e-18 1589.19133432374 176.740033792853 8.99168852817095 4.06156251204629e-18 282.420415688469 556.167803537601 0.507797132254124 0.611802199325547 BLOC1S5-TXNDC5 other 4.93505982619141e-14 1 5.46605082871189e-14 8.99168852817095 0.507797132254124 0.00270921638795897 0.330584994378934 8.05371130896055 0.041047534695107 0.967273458581035 59.9517969679072 18.1907796314887 3.29572443745783 0.00104738151674567 LINC00639 other 1 1 1 0.041047534695107 3.29572443745783 1.86491628894569e-08 34.1809651730309 24.3826610957639 1.40185540203277 0.161542693632879 -347.690516132597 65.1857424004094 -5.33384300506814 1.4254849986745e-07 POC1B-GALNT4 other 0.000142013375403215 0.00187494041875656 1 1.40185540203277 -5.33384300506814 1.04128138814243e-103 679.632540879549 25.331687511957 26.8293433099847 2.06010521639163e-99 -194.377032263049 145.620328052268 -1.33482072773027 0.182532937484021 NDUFC2-KCTD14 other 1.62710629711135e-99 1 3.21870839009028e-95 26.8293433099847 -1.33482072773027 0.638242451747288 -0.0532810690785472 2.12911088350039 -0.0250250325107304 0.980044398225104 -5.72112618114631 6.20464022516808 -0.922072186867422 0.35690967646906 LRP1-AS other 1 1 1 -0.0250250325107304 -0.922072186867422 0.155629013462182 -34.2951612699244 27.1060864660791 -1.26521994655487 0.206347416256722 -122.970784873277 67.1708046904808 -1.8307177566194 0.0677029369788799 ITGB3 other 1 1 1 -1.26521994655487 -1.8307177566194 0.721322494032544 -0.386098754600519 0.629909558367717 -0.612943159016376 0.540170552152727 -1.01598162530153 1.53007080318331 -0.664009549876897 0.506966039033279 ANKRD34C-AS1 other 1 1 1 -0.612943159016376 -0.664009549876897 9.76197912799399e-39 80.4592636660467 7.27219236627029 11.0639625045167 8.72093021012462e-26 -91.8401776483617 16.1066800138217 -5.70199305937353 1.95125846306905e-08 USP3-AS1 other 1.42134416103592e-34 0.000264180883314918 1.25468022933063e-21 11.0639625045167 -5.70199305937353 0.000312658032171054 61.0807602324149 16.5476487254861 3.69120478961706 0.000246251436124597 8.70644756208875 29.1867388034672 0.298301486189149 0.765589759128578 BUB1B-PAK6 other 1 1 1 3.69120478961706 0.298301486189149 6.6070749816788e-24 50.2380180385523 4.68020032625319 10.7341597659285 1.62716861677768e-24 -5.29923920680321 29.2190323099561 -0.181362584174205 0.856150413539773 ZNF710-AS1 other 8.39494947172108e-20 1 2.32327135103517e-20 10.7341597659285 -0.181362584174205 1.8923044240438e-78 117.468158273374 5.22963475273046 22.4620195917206 3.04812978990163e-79 158.942162665593 58.4795758918934 2.71790894926149 0.00678222616358261 ZHX1-C8orf76 other 2.94158722717608e-74 1 4.74593808287684e-75 22.4620195917206 2.71790894926149 1.90091110855053e-25 112.486118665612 11.1382950467392 10.0990428242016 4.25505369585532e-22 -61.9163416065473 27.3632365325909 -2.2627565102835 0.0240434355554045 ST20-MTHFS other 2.47270517000253e-21 1 5.95960601172351e-18 10.0990428242016 -2.2627565102835 1.88842687462633e-32 350.543260665206 27.0294742647972 12.9689263368969 1.33578842642272e-33 339.84264405061 178.535173282769 1.90350527462932 0.0575160658052444 TGIF2-C20orf24 other 2.64285341103955e-28 1 1.98805391504493e-29 12.9689263368969 1.90350527462932 2.04103292803402e-08 8.63677508384736 1.45827609041476 5.92259253279735 5.68538479756868e-09 9.19716119495587 3.13049638215011 2.9379242369988 0.0034471871416468 UBE2Q2P2 other 0.000155098092201305 1 6.14533242769198e-05 5.92259253279735 2.9379242369988 2.53321838978527e-43 201.434877581797 18.0730536083194 11.1455917714466 4.14500426646072e-26 -419.654456363191 59.7928832941188 -7.01846830665327 6.75658975078333e-12 THTPA other 3.76106934331419e-39 9.83421638226514e-08 5.97419464924984e-22 11.1455917714466 -7.01846830665327 0.00327183969342014 28.6503470456351 8.44525984467938 3.39247667597642 0.000743124878066632 8.42897037159078 28.0618570110637 0.300371082650289 0.764009080655508 LINC01833 other 1 1 1 3.39247667597642 0.300371082650289 6.71086491455091e-17 3.31918965952487 0.377449397481491 8.79373415793471 2.07624832547996e-17 -1.99726927022628 2.99406192050021 -0.667076808449104 0.505016149909557 ADNP-AS1 other 7.34839708143325e-13 1 2.76660089370204e-13 8.79373415793471 -0.667076808449104 1.29876869886734e-31 109.297231806797 9.4078474439918 11.6176662576091 5.14304681237716e-28 -38.3030114608255 22.4035214523891 -1.70968709281821 0.087896110479408 MRPL46 other 1.80398972272674e-27 1 7.49187629158982e-24 11.6176662576091 -1.70968709281821 0.0032193362542844 13.3055455031236 6.31098157356162 2.10831632893116 0.0354619937415865 -14.7689299938523 11.4603631913887 -1.28869650526867 0.198053408197622 ANP32AP1 other 1 1 1 2.10831632893116 -1.28869650526867 1.92737805029899e-13 1.9269280844025 0.755667319524609 2.54996879528247 0.0110462928655553 -6.82221391450637 1.29852577001569 -5.25381480447933 2.14205635962842e-07 INO80-AS1 other 1.87610979416104e-09 0.0027923846704116 1 2.54996879528247 -5.25381480447933 0.729625774953567 -11.4728996369829 63.1919865088659 -0.181556242663352 0.855998867287965 -120.119102180753 151.477971949779 -0.792980660056481 0.428136069062231 LINC00052 other 1 1 1 -0.181556242663352 -0.792980660056481 5.92340391440086e-37 94.0292469068034 7.91776433374623 11.875731954542 4.5694949250712e-29 -62.6235147562966 17.1318616781818 -3.65538293109443 0.000281850344253193 IQCH-AS1 other 8.54628716769756e-33 1 6.68654192385669e-25 11.875731954542 -3.65538293109443 0.000299743874947435 23.5413327298515 17.5841285634349 1.3387830192964 0.181201531733657 217.655095096616 53.9024525387653 4.03794419075986 6.16839223313708e-05 HSP90B2P other 1 0.70646596246119 1 1.3387830192964 4.03794419075986 0.0437414148366494 1.50038345582403 0.844950200791694 1.77570637230243 0.0763486271025259 4.78279419275952 2.20334523811688 2.17069667976645 0.030392326198361 LINC00933 other 1 1 1 1.77570637230243 2.17069667976645 1.51852621932448e-13 4.78748203377645 0.771927184774459 6.20198657101998 1.1067989132888e-09 -8.03121631333089 2.37887319588162 -3.37605902123525 0.000788035375399116 CRTC3-AS1 other 1.48390382152388e-09 1 1.22998563233784e-05 6.20198657101998 -3.37605902123525 0.116058819389146 7.20427406380306 4.1373782212567 1.74126552578382 0.082215103922606 1.87765071457901 8.88386863857862 0.211355074119986 0.832691148925628 SLC22A31 other 1 1 1 1.74126552578382 0.211355074119986 0.00906806842411076 2.9244046949787 1.39430861855652 2.0973869458013 0.0364443534234583 21.5610503072059 8.81860589307085 2.44494998060264 0.0148199605958754 LYPD8 other 1 1 1 2.0973869458013 2.44494998060264 0.0123238068033123 1.97906951827563 2.07741845414499 0.952658100406719 0.341188760795099 35.2119818728478 11.8805247489576 2.96384062294363 0.00317206449439674 IL21R-AS1 other 1 1 1 0.952658100406719 2.96384062294363 3.99904211176823e-24 129.238734585688 50.298229966748 2.56944895816667 0.0104625594162298 -738.154392400268 92.1273674355367 -8.01232481669216 7.3997975555233e-15 RBM15B other 5.09957850092684e-20 1.11019162725516e-10 1 2.56944895816667 -8.01232481669216 0.0134015542089683 -70.1918313612269 57.7196924643018 -1.21608117376299 0.224485319209817 -536.845596686763 188.361540269203 -2.85008073261406 0.00453777762142297 MIR568 other 1 1 1 -1.21608117376299 -2.85008073261406 0.179975116280031 2.71406056596923 2.65607613032129 1.02183086357578 0.307313484664081 -8.19157763033542 7.38037637702989 -1.10991326347939 0.267524985699933 TGFBR3L other 1 1 1 1.02183086357578 -1.10991326347939 2.12146928742748e-10 43.9263670380347 6.44858842629355 6.81178021207383 2.64324809030392e-11 33.2246217944843 26.4851649616516 1.25446157660679 0.210231424608633 HOXB7 other 1.8049460697433e-06 1 3.0970937874091e-07 6.81178021207383 1.25446157660679 1.62402136301194e-32 2087.93154080812 176.910986216681 11.8021587322497 1.03987245887091e-28 -4602.92382367493 1193.90992355246 -3.85533592850875 0.000129735581283051 NORAD other 2.27460432103453e-28 1 1.51935764965629e-24 11.8021587322497 -3.85533592850875 2.48242086658681e-12 52.4116756183056 7.50900682093219 6.97984125839415 8.97400510313447e-12 -44.5012465950449 44.9289628557045 -0.990480166167351 0.322396621475347 MIR762HG other 2.30939613218571e-08 1 1.06656050650753e-07 6.97984125839415 -0.990480166167351 4.15290259649481e-10 7.09906768860124 1.18203442293699 6.00580452721693 3.48820393968402e-09 -3.34523431618055 3.43404740974361 -0.974137487644735 0.330422031585887 SPDYE6 other 3.47348773170826e-06 1 3.79830526992193e-05 6.00580452721693 -0.974137487644735 0.240627653174982 -4.84431672127524 8.71827611038963 -0.555650757092017 0.578682338598406 -32.7053546419086 19.4237615427945 -1.68378069149233 0.0928084725686483 AOC4P other 1 1 1 -0.555650757092017 -1.68378069149233 6.61776421061678e-07 48.2532851680267 9.76583210662118 4.94103161320081 1.03604075979594e-06 -16.3802917421265 31.8652391113221 -0.514048919730414 0.607426531717972 JHDM1D-AS1 other 0.00449015301690348 1 0.00995738774239874 4.94103161320081 -0.514048919730414 1.03729295123487e-17 97.5189704491747 10.629458579495 9.17440617693326 9.65318319130766e-19 -3.32309392681886 95.5472829658025 -0.0347795753439502 0.972268407097636 PMF1-BGLAP other 1.16176810538305e-13 1 1.30926123623706e-14 9.17440617693326 -0.0347795753439502 0.58201237692902 12.3699025492726 13.739438704603 0.90032080751075 0.368350879391054 -12.863704241139 62.4774157907369 -0.205893666988804 0.836951570602245 SNHG19 other 1 1 1 0.90032080751075 -0.205893666988804 1.01968852379756e-13 165.942037839731 22.3445396270851 7.42651406603978 4.41844135020064e-13 -126.123649908966 132.518292397969 -0.951745209108194 0.341655184301654 SLX1B-SULT1A4 other 1.00276169430252e-09 1 5.41259065399578e-09 7.42651406603978 -0.951745209108194 0.000636222324985255 6.22790974561742 3.21248636803554 1.93865717457529 0.0530817696693582 -21.2674403841492 9.00339098654333 -2.36215892611306 0.018534883991953 TBC1D3G other 1 1 1 1.93865717457529 -2.36215892611306 0.00415655748785482 36.2864627631654 18.7449863623215 1.93579563419173 0.0534202041664185 219.065747055822 73.7512091767773 2.97033431046174 0.00310858691957539 MRC1 other 1 1 1 1.93579563419173 2.97033431046174 3.5428875911023e-11 5.07554207214791 1.35367905562496 3.74944271395606 0.000196468161026908 -14.2647438334119 2.98012946063925 -4.78661884385119 2.19582408166894e-06 HEXA-AS1 other 3.12624401038867e-07 0.0274543884931068 1 3.74944271395606 -4.78661884385119 0.0101500856895846 3.90565960550381 1.29268293249749 3.02135930421701 0.00264585305146834 0.337474114217706 8.83132041652724 0.0382133246559762 0.969532910557448 SCX other 1 1 1 3.02135930421701 0.0382133246559762 0.153002490783162 16.321894554489 8.59858192874065 1.89820771491788 0.058206639055328 4.64373047307755 51.5177643763512 0.0901384314574258 0.928210944879485 ATP2A1-AS1 other 1 1 1 1.89820771491788 0.0901384314574258 1.17038807457427e-21 16.6932915309053 3.18261843131417 5.24514386225442 2.24307678706554e-07 -24.5663098251844 6.79624959008951 -3.61468623239025 0.000328745205298159 C16orf95 other 1.43185277043416e-17 1 0.00224644140224614 5.24514386225442 -3.61468623239025 0.011321825055139 -14.671677242548 13.0511748842993 -1.12416524739073 0.261443327890532 -80.3021885158034 27.9197259113863 -2.87618111906515 0.00418447861677995 MT1L other 1 1 1 -1.12416524739073 -2.87618111906515 1.424795672755e-13 6.19911956809982 1.60030797634878 3.87370409928441 0.000120528718935269 -10.0783468250798 3.44038553913354 -2.92942366791195 0.00354132805057409 SNAI3-AS1 other 1.39359264752166e-09 1 0.987732851674529 3.87370409928441 -2.92942366791195 0.00666599737069566 2.18632814273386 9.38599273367512 0.232935205126437 0.815899174557516 -64.2315832084862 21.5705283284196 -2.97774733333072 0.00303290674186308 LINC01963 other 1 1 1 0.232935205126437 -2.97774733333072 6.26679713729748e-10 30.5630767346324 5.4769112791778 5.58034906477809 3.85437133646431e-08 -70.8385407054484 32.8212952303893 -2.15831033504915 0.0313572036022394 FBXL19-AS1 other 5.18953470939604e-06 1 0.00040235782381351 5.58034906477809 -2.15831033504915 0.0714244704442034 -25.2721496840865 57.5462206235758 -0.43916263153749 0.660720025286615 -264.092568135256 125.926603753749 -2.097194399459 0.0364425056280834 TAT-AS1 other 1 1 1 -0.43916263153749 -2.097194399459 1.27933981601408e-10 8.51017679910938 1.23567938585147 6.88704278516817 1.59210772883216e-11 5.84769289671058 2.70532346472607 2.16155035542218 0.0310923777235879 ADPGK-AS1 other 1.09690595825047e-06 1 1.87820948770329e-07 6.88704278516817 2.16155035542218 0.533747741879061 6.32751710959691 7.87276904870197 0.803721926866401 0.421917229284449 -30.4711189335102 45.6984200935698 -0.666787142118242 0.505197726079415 XKR7 other 1 1 1 0.803721926866401 -0.666787142118242 0.00281676330074126 1.70505240443013 0.849416817585648 2.00732122219632 0.0452477962177475 -7.43537578193221 3.23477533040285 -2.29857564203887 0.0219366085508206 LINC00622 other 1 1 1 2.00732122219632 -2.29857564203887 0.00454113510769787 4.21350162395473 2.3125196217315 1.82203929616816 0.0689959369889916 -8.62879423486465 4.49664296768352 -1.9189413740157 0.0555127534532266 CAPN10-AS1 other 1 1 1 1.82203929616816 -1.9189413740157 7.05712553914842e-05 2.51070783972374 5.59512410923379 0.448731393746967 0.65381984389179 173.616399959548 39.3486854424827 4.41225413269089 1.25383507592152e-05 WFDC21P other 0.391247039890388 0.15049782416286 1 0.448731393746967 4.41225413269089 3.76124820468441e-13 16.268897780807 2.13475541269908 7.62096570128257 1.19152466551354e-13 8.35040843704015 4.08409703021215 2.0446155846122 0.0413928843379544 LMO7-AS1 other 3.61305502541984e-09 1 1.48118431169988e-09 7.62096570128257 2.0446155846122 0.18807455032077 31.9226376860375 19.9145902909478 1.60297737586637 0.109520076701142 -21.0796315066509 65.279938845132 -0.322911324360453 0.746886476286943 TMEM178B other 1 1 1 1.60297737586637 -0.322911324360453 4.35197672125468e-11 10.9965241411897 2.89823749690039 3.79421084467726 0.000165743411898195 -21.9650084718238 5.96604989627713 -3.68166690753461 0.000256220753387732 RBFADN other 3.82190595660586e-07 1 1 3.79421084467726 -3.68166690753461 1.88865327658942e-07 335.22313032374 63.1107917380386 5.31166098684343 1.6380095172939e-07 -538.100913378851 425.563224871049 -1.26444411060637 0.206659749792205 EPPK1 other 0.0013390551731019 1 0.00165160499628743 5.31166098684343 -1.26444411060637 3.1880257521857e-08 126.814870762762 32.7247903105494 3.87519276851962 0.000119560128150293 -78.7126704963292 69.8569391814917 -1.12676952953564 0.260337629410167 LINC02188 other 0.000239101931413927 1 0.980273490704254 3.87519276851962 -1.12676952953564 3.89895949098785e-15 31.1502430879436 16.2057675108595 1.92217018213236 0.0551062904204235 -179.810905240121 28.471503929579 -6.31546916822036 5.60136694319609e-10 SPINT1-AS1 other 4.0424412002562e-11 7.89232602296329e-06 1 1.92217018213236 -6.31546916822036 1.21888109567489e-19 85.7649973406122 9.67894601160541 8.86098519795201 1.19591720641712e-17 -104.473390719968 42.23398993242 -2.47368034341865 0.0136845828736424 ZNF865 other 1.43352605662324e-15 1 1.59918048842098e-13 8.86098519795201 -2.47368034341865 9.13266118594672e-07 73.1270811682005 16.3467527941293 4.47349281469915 9.48040350747856e-06 -169.444951145312 96.3523557298361 -1.75859686939488 0.0792410550896545 PYCARD-AS1 other 0.00612618912353306 1 0.0855701220585015 4.47349281469915 -1.75859686939488 0.0598873477545697 -198.99493106242 91.7837189449275 -2.16808529170431 0.0306059101302584 -553.922298814483 403.790350703578 -1.37180667603698 0.170716321563615 PECAM1 other 1 1 1 -2.16808529170431 -1.37180667603698 3.6673670426318e-09 64.6667458729044 13.3379430209556 4.84832974404709 1.64002686267987e-06 -4.62121580930732 28.7693742122908 -0.160629695147594 0.872446501923059 VPS9D1-AS1 other 2.91408985207523e-05 1 0.0155753351148707 4.84832974404709 -0.160629695147594 1.22831276107038e-14 14.2904580992164 1.77178279370545 8.06558126085523 4.78160266094011e-15 2.01461700320716 3.90058639042594 0.516490804601091 0.605724282352372 TMEM202-AS1 other 1.25066805332186e-10 1 6.11901692520506e-11 8.06558126085523 0.516490804601091 4.1678694090628e-10 21.1875528190095 4.68419224060153 4.52320309046255 7.48851515900916e-06 -39.5545591258473 13.1287284954693 -3.01282482454393 0.00270918850778474 LINC01003 other 3.48475561291741e-06 1 0.0681005568560293 4.52320309046255 -3.01282482454393 0.0944186673525698 1.06561537515441 0.97816442960512 1.08940311352826 0.276477863071348 -6.65979808677622 3.94515351822023 -1.68809605406196 0.0919889458085007 TUBB8 other 1 1 1 1.08940311352826 -1.68809605406196 0.136239204712939 3.35610295439881 4.99189902556314 0.672309863883956 0.501676153570715 -15.2186379015569 11.0633585006197 -1.37558932947029 0.169523381384592 DLGAP1-AS5 other 1 1 1 0.672309863883956 -1.37558932947029 0.0257456658501214 7.98572552946561 3.02626818983937 2.63880298391184 0.00856013891404804 7.13004629184579 6.63979244414225 1.07383571878607 0.283375925112457 SMG1P7 other 1 1 1 2.63880298391184 1.07383571878607 4.06870717215754e-11 5.82166665776367 0.822475585824093 7.07822427571581 5.00202058907216e-12 7.30746652702925 5.61896240826305 1.30050105270025 0.194032001738269 TMEM249 other 3.5820897943675e-07 1 5.98291682658921e-08 7.07822427571581 1.30050105270025 0.902007655130124 0.573701431080229 1.34781082738705 0.425654267960171 0.670536922708868 1.66725874852423 6.23301668768423 0.26748825361218 0.789199931087318 TPBGL other 1 1 1 0.425654267960171 0.26748825361218 5.28606033863752e-21 4.76622044035357 2.67156413277501 1.78405615717067 0.0749749039692634 -42.0615765470087 5.00839898343948 -8.3982080273731 4.00040464690573e-16 C15orf65 other 6.38767531320958e-17 6.05381235216244e-12 1 1.78405615717067 -8.3982080273731 1.44680888847377e-05 -12.6790996040576 4.07922437028827 -3.10821333987118 0.00198134619277922 -36.9707938968923 8.26103123076172 -4.47532431050782 9.31060483708536e-06 TTC39A-AS1 other 0.0868085333084263 0.112621076109385 1 -3.10821333987118 -4.47532431050782 0.250899508820998 -68.2496996449037 79.7094141336895 -0.856231354685841 0.39224612016179 -296.978070950698 178.952635907581 -1.65953448768461 0.0975834058298944 HPR other 1 1 1 -0.856231354685841 -1.65953448768461 4.91606206136868e-17 146.676276168261 16.8267453359662 8.71685363031844 3.61680564545847e-17 2.20293388678017 101.30583473388 0.0217453801409075 0.982659187015654 BOLA2-SMG1P6 other 5.40717666129941e-13 1 4.80384125829794e-13 8.71685363031844 0.0217453801409075 0.000162192565110513 -7.34891321400065 1.94022677544099 -3.78765683837671 0.000169155801184055 -3.3196331085074 4.19711047656323 -0.790932982832906 0.429330334986308 LINC00922 other 0.857674284304393 1 1 -3.78765683837671 -0.790932982832906 4.82165165039577e-18 67.7738447610707 69.641393256288 0.973183355359584 0.330897100796004 -1052.71487993128 130.557181432064 -8.06324760066201 4.80148193429686e-15 DNAAF4-CCPG1 other 5.44557337395698e-14 7.20990527254017e-11 1 0.973183355359584 -8.06324760066201 2.49622081617246e-16 171.951164278207 23.0916203639858 7.44647458982074 3.81610107887768e-13 -242.843679140146 76.9239115799574 -3.15693357438962 0.0016833810499734 ISY1-RAB43 other 2.68942830734421e-12 1 4.68540890464601e-09 7.44647458982074 -3.15693357438962 1.65199091340389e-11 28.3522361060087 9.95094917086861 2.84919916875968 0.00454955840486191 -109.495314338328 19.6755440651037 -5.56504633244313 4.12533269918684e-08 LOXL1-AS1 other 1.48034905750123e-07 0.000552959594999004 1 2.84919916875968 -5.56504633244313 0.000493363278265065 242.996401382981 62.1868027029486 3.90752363558096 0.000104933783217401 176.190327646572 239.392624841671 0.735988954392811 0.462052903949523 MIA other 1 1 0.865388910193906 3.90752363558096 0.735988954392811 0.0129609621432722 29.2965361879325 78.9602303564906 0.371029011132112 0.710761706722124 -507.553592944003 195.061508964987 -2.60201818204486 0.00952256283055947 PCDHGA9 other 1 1 1 0.371029011132112 -2.60201818204486 0.567900219203285 -30.3570640053524 118.613906546831 -0.255931744338654 0.798101914887924 -337.45848178347 322.349878478057 -1.0468702000967 0.295632172829914 SNORD3B-2 other 1 1 1 -0.255931744338654 -1.0468702000967 0.0127262727626399 33.5691587115743 78.1067605603036 0.429785571322686 0.667523074448058 -497.400490198841 193.001499866066 -2.57718458428569 0.0102250501355976 PCDHGB3 other 1 1 1 0.429785571322686 -2.57718458428569 1.8047619602823e-14 116.638207554153 16.1185193376385 7.23628548695475 1.58136253404348e-12 -140.606051318497 80.6993354699731 -1.74234459924164 0.0820143267785084 CORO7 other 1.82605815141364e-10 1 1.91534630123347e-08 7.23628548695475 -1.74234459924164 0.116547016996971 80.097385843936 44.4983945823878 1.80000619338384 0.0724145833462512 167.428265290931 89.7882048441176 1.86470222432451 0.0627624140386973 MMP12 other 1 1 1 1.80000619338384 1.86470222432451 1.27528042042299e-19 25.1726395119855 3.05440840416131 8.24141247047725 1.28354956567681e-15 -41.6359895763932 15.2922686821575 -2.72268232018267 0.00668361641532992 LINC01569 other 1.49883707812314e-15 1 1.65821768389787e-11 8.24141247047725 -2.72268232018267 0.0112469624169196 37.0836343649696 81.0644987164983 0.457458381315104 0.647525601727545 -521.375599434902 200.310059282199 -2.60284281929338 0.00949950525602676 PCDHGA4 other 1 1 1 0.457458381315104 -2.60284281929338 0.0228196969456133 -205.829688538513 88.3724962371376 -2.32911479592239 0.0202237145140899 -461.094833663418 200.965054392198 -2.29440304961457 0.0221530847698609 SPON1 other 1 1 1 -2.32911479592239 -2.29440304961457 8.24780660909667e-46 169.660992293953 21.2564963550211 7.98160663264135 8.61796873087673e-15 -357.631719198715 39.0865339019144 -9.14974246875339 1.14120850692075e-18 OVCA2 other 1.23461417131568e-41 1.74970088281089e-14 1.09810157568831e-10 7.98160663264135 -9.14974246875339 0.00591404924369441 9.68104274529021 6.03891610581328 1.60310932883649 0.109499601145158 -42.2945060786288 17.1290096214132 -2.46917405112295 0.0138531670000078 LINC01977 other 1 1 1 1.60310932883649 -2.46917405112295 4.92819675838911e-15 374.771732847722 44.7713446269702 8.37079466722024 5.08420863063524e-16 151.582540382979 125.792872429641 1.20501692548409 0.228732517600675 MRPL12 essential 5.09279853011931e-11 1 6.61811437449789e-12 8.37079466722024 1.20501692548409 2.08556845890649e-05 12.6389920722833 3.9867399242994 3.17025748162001 0.00160829413125246 -12.9895935020428 7.21608026901448 -1.80008994049298 0.0723972840786996 ALOX12P2 other 0.123027683390894 1 1 3.17025748162001 -1.80008994049298 1.0149097571448e-09 398.399948093294 106.072460139419 3.75592257942964 0.000192104107355357 -1762.3233254585 405.075379639889 -4.35060587248032 1.63297595930762e-05 GTF2I other 8.30297672320161e-06 0.1948140319454 1 3.75592257942964 -4.35060587248032 2.40322689861264e-19 38.001440394445 5.53064606509114 6.87106713161526 1.74327773217292e-11 -83.1749727458606 18.7535381852653 -4.43516161719346 1.11299125545733e-05 ZNF234 other 2.80744966295928e-15 0.133993017244508 2.05305818518005e-07 6.87106713161526 -4.43516161719346 0.0137153622205508 49.676973515043 29.2171264572771 1.70026897024536 0.0907428402160486 -84.0753535613264 61.3194399435131 -1.37110439427979 0.171985613842562 ROCK1P1 other 1 1 1 1.70026897024536 -1.37110439427979 0.115527572537273 86.6091171681005 47.0675000991689 1.84010446668337 0.0662994840022649 -17.9583032675922 87.2308398714575 -0.205871034763111 0.83696895471714 MYZAP other 1 1 1 1.84010446668337 -0.205871034763111 0.00177895062234253 10.5433818717094 5.36289653703667 1.96598644014403 0.0498083032752832 -17.1167582325535 10.2430017361445 -1.67106856695665 0.0952832640571086 TAPT1-AS1 other 1 1 1 1.96598644014403 -1.67106856695665 0.37644032235133 2.7774847173963 2.0972033567346 1.32437548723025 0.186037428078891 -1.45723912407202 7.68125094699924 -0.189713776327189 0.849617290787521 PPIAL4A other 1 1 1 1.32437548723025 -0.189713776327189 0.330584257039231 -0.837093511240296 1.15383142090915 -0.725490306530839 0.468466738975129 -3.09883047489351 2.08295182261048 -1.48771106525636 0.13741296432097 TMEM220-AS1 other 1 1 1 -0.725490306530839 -1.48771106525636 0.188612349824294 1.73438316851591 0.950148917935898 1.82538035435927 0.0685448490316589 0.276100864605996 10.760710177521 0.0256582381693327 0.979540253485118 PPIAL4C other 1 1 1 1.82538035435927 0.0256582381693327 1.87718816315581e-41 150.929961507548 30.0229583733016 5.02715154285943 6.79397650993743e-07 -548.046211872677 60.8154177418939 -9.01163277704733 3.5522466219703e-18 SRSF8 other 2.76622447722641e-37 5.43529255627676e-14 0.00660646275826315 5.02715154285943 -9.01163277704733 5.7652533400069e-09 52.8857878910012 8.80946546688987 6.00329135629977 3.55833791351438e-09 128.879296261995 73.008084237627 1.76527432006733 0.0780849126718136 IKBKE other 4.52802997324142e-05 1 3.87360665265175e-05 6.00329135629977 1.76527432006733 0.939982053381834 -32.6197020087282 290.308289281986 -0.112362282487372 0.910577456746217 -289.786511325367 823.704300605357 -0.351808908988817 0.725117309741468 MSMB other 1 1 1 -0.112362282487372 -0.351808908988817 5.35231133829057e-13 84.473072434026 22.262092806397 3.79448029296476 0.000164884247117282 -210.791893711908 49.3556662078803 -4.27087525926764 2.30505188830481e-05 LINC00667 other 5.10449932332772e-09 0.271811718668903 1 3.79448029296476 -4.27087525926764 1.99518698777102e-06 -3.48863081266706 2.60080155201596 -1.34136755261581 0.180374553337507 -27.1427588575283 5.31871137880383 -5.10325846326195 4.65700286081808e-07 LINC00908 other 0.0129806865424382 0.00600008248587802 1 -1.34136755261581 -5.10325846326195 3.72561337461039e-77 16.1984837410595 0.737037445133864 21.9778300926318 6.7723645447526e-76 -7.21348454836919 5.43850920649857 -1.32637167180846 0.185307947246 LINC00672 other 5.78662269344486e-73 1 1.05344130493627e-71 21.9778300926318 -1.32637167180846 0.583095778626429 -95.1517595208075 394.331742820882 -0.241298757335973 0.809416197651363 -1147.71213453252 1122.96692485065 -1.02203556412417 0.307226848854635 SNORD3A other 1 1 1 -0.241298757335973 -1.02203556412417 5.72771148774885e-06 55.8138885494547 11.2467840797754 4.96265315965496 9.64800869159039e-07 23.5656349167812 142.561793127727 0.165301196062172 0.868775936704831 NBPF11 other 0.0355404497814816 1 0.00929006756913238 4.96265315965496 0.165301196062172 0.237164204788346 4.49803534221517 14.0178775991524 0.320878486090301 0.748427082042511 196.433021751723 118.521176621494 1.65736645003995 0.0980283765146322 C1orf186 other 1 1 1 0.320878486090301 1.65736645003995 7.67330388032941e-38 66.9071187241524 7.2270436118736 9.25788224305552 4.90333859694909e-19 -85.2628585940091 14.6665400456622 -5.81342691108843 1.04888463045923e-08 LINC00909 other 1.11262906264776e-33 0.000143288129367036 6.67050182728955e-15 9.25788224305552 -5.81342691108843 4.1503876935451e-47 763.414994539669 51.9016358585733 14.7088811732235 3.55045594262262e-41 -774.288259081204 205.023213449916 -3.77658825092189 0.000177422921455686 DYNLL2 other 6.2305620055499e-43 1 5.37716552510196e-37 14.7088811732235 -3.77658825092189 5.75079844436208e-10 213.012011034874 32.0223885391557 6.65197134730944 7.49539348905888e-11 -24.4424633231947 392.047542117396 -0.0623456614245922 0.950312088622183 OTUD7B other 4.77373778866497e-06 1 8.66467487335207e-07 6.65197134730944 -0.0623456614245922 1.89423326190241e-19 4.13122970030743 4.90914564646318 0.841537407488368 0.400422927735906 -99.3768687336235 11.6324041080828 -8.54310663644943 1.36618580982412e-16 MAPT-AS1 other 2.21720003305677e-15 2.07346020357007e-12 1 0.841537407488368 -8.54310663644943 0.410363990478913 3.34467441259938 2.54799818572985 1.312667501622 0.189867454247403 0.308021187831494 11.4837277076995 0.0268224043334791 0.978611556467718 SEPT4-AS1 other 1 1 1 1.312667501622 0.0268224043334791 1.97844763084124e-11 40.7006971230897 6.56388521264607 6.20070214583814 1.11392197387951e-09 -23.8982354171432 17.1874728707756 -1.39044498262325 0.164963410988598 DSG2-AS1 other 1.76754511339356e-07 1 1.23779009737492e-05 6.20070214583814 -1.39044498262325 0.572802169938186 -40.554120553337 162.369846282665 -0.24976386614752 0.80286601465438 -480.711719399275 462.392313801987 -1.03961875024837 0.298987543038753 SNORD3C other 1 1 1 -0.24976386614752 -1.03961875024837 1.02758222944544e-06 5.92724415204687 3.17046324091905 1.86951990975574 0.062087499430382 -35.545674951267 8.54076134255898 -4.16188598715918 3.66849799106204e-05 AGAP12P other 0.00685089072371275 0.426683001340426 1 1.86951990975574 -4.16188598715918 0.353562841598573 -1.11714499095979 13.6161789127266 -0.0820454106926894 0.934644242520984 -247.979831461746 172.562782054508 -1.43704122354388 0.151347108240601 GJA5 other 1 1 1 -0.0820454106926894 -1.43704122354388 6.82104809783568e-70 90.2488097690092 4.57450303464212 19.7286588478719 3.31279035830865e-65 -57.2387803395503 20.6349645940713 -2.7738734456562 0.00573686209301429 TSPOAP1-AS1 other 1.05535256169714e-65 1 5.13084970694843e-61 19.7286588478719 -2.7738734456562 0.574227067032774 -27.8897078501339 116.59888701299 -0.23919360265443 0.811047065848337 -327.590863721417 316.873781106556 -1.03382129811257 0.301686798073419 SNORD3B-1 other 1 1 1 -0.23919360265443 -1.03382129811257 0.832499721728399 -0.478797770759617 0.923926217659075 -0.518220786041479 0.604524654774243 -1.68283093665026 4.09384843538915 -0.411063321764205 0.681195450925182 MIR142 other 1 1 1 -0.518220786041479 -0.411063321764205 1.53740332085503e-34 376.222937298619 31.299145907606 12.0202301497049 1.08189695653535e-29 -187.904735593446 89.1471165155263 -2.10780497382346 0.0355030558738776 TIMM23 essential 2.18634126258794e-30 1 1.58833292188955e-25 12.0202301497049 -2.10780497382346 0.000319934883230041 -29.7713701025244 17.4992280889308 -1.70129619153638 0.0894716973999768 -158.934712909443 39.3809992303156 -4.03582224970804 6.23972462995376e-05 PCAT18 other 1 0.714448470129705 1 -1.70129619153638 -4.03582224970804 8.11198707829846e-08 17.0569654375696 5.78291975637031 2.94954212684348 0.00332090298397328 -82.9244443540846 19.7400066620796 -4.20083162957497 3.11281809341569e-05 DTX2P1-UPK3BP1-PMS2P11 other 0.00059037011448873 0.363732794215624 1 2.94954212684348 -4.20083162957497 1.79004940559793e-05 -1.05824434037716 5.37804115625546 -0.196771335441765 0.844085962663906 -89.2115317039953 19.704821213043 -4.52739615038701 7.46275368688021e-06 KRT18P55 other 0.106418437162797 0.0908067868619584 1 -0.196771335441765 -4.52739615038701 8.25380939916745e-10 7.18426464640105 2.21778248415337 3.23939101229922 0.00127153819724324 -17.0288630390659 4.52943114979173 -3.75960302208124 0.000188748321010822 MIR1539 other 6.78298056423581e-06 1 1 3.23939101229922 -3.75960302208124 2.66541384589991e-25 11.3500374897894 1.3937834218767 8.14332938076332 2.92114917305892e-15 -46.4516346657986 8.09954191993889 -5.73509404913965 1.66303089021438e-08 RARA-AS1 other 3.45757484090137e-21 0.000225756443346602 3.75133976804226e-11 8.14332938076332 -5.73509404913965 5.70301916677776e-18 437.90119803565 142.186252168158 3.07977171743553 0.00217700739876352 -1890.05440546072 290.390443717682 -6.50866599211588 1.73388898713671e-10 RPL17 essential 6.43186501629196e-14 2.46784419539168e-06 1 3.07977171743553 -6.50866599211588 1.20951602304873e-21 53.988165959941 6.22653612135959 8.67065811675601 5.27751484883404e-17 -67.1287158039943 17.5226394893278 -3.83097054783779 0.000142955628927372 MAFG-AS1 other 1.4792380961886e-17 1 6.99481818064464e-13 8.67065811675601 -3.83097054783779 0.446205877413987 4.662587296527 4.07613173931698 1.14387551598327 0.253178350427015 -1.87099081603693 10.888588680909 -0.171830424572595 0.863634746495669 ZNF488 other 1 1 1 1.14387551598327 -0.171830424572595 0.200582774749147 11.5908689755682 14.7660510262536 0.784967419857886 0.432834314710688 -41.9971621156614 36.352604418126 -1.15527244300331 0.248515638046089 CXADRP3 other 1 1 1 0.784967419857886 -1.15527244300331 0.15984270120782 -14.1705169726537 10.036130510414 -1.411950248948 0.158569707321652 -43.510237120103 24.7079927927307 -1.76097821806489 0.0788366724910807 CYP4F35P other 1 1 1 -1.411950248948 -1.76097821806489 2.69921096104018e-24 490.507573000965 44.9906521367024 10.9024330545504 7.12858179512413e-25 95.9290189307635 166.696943837731 0.575469572040533 0.565243995289474 SEC22B other 3.45202089807429e-20 1 1.02045648397202e-20 10.9024330545504 0.575469572040533 4.88930180566462e-40 40.8398293370416 2.79298144952342 14.6223059748608 5.73863529931439e-41 67.3412755589626 32.3944086166925 2.07879317556865 0.038113176640049 FSBP other 7.16282714529867e-36 1 8.68886770669192e-37 14.6223059748608 2.07879317556865 0.541140824672995 88.960628946481 80.2733425016543 1.10822131200837 0.268260513573499 73.2377117017923 183.620180008349 0.398854372642823 0.690158475743827 LINC00668 other 1 1 1 1.10822131200837 0.398854372642823 0.0507601244444597 -5.21972556016174 3.59820372187736 -1.45064759074796 0.14745970202527 -18.318162713441 7.58241119774066 -2.41587566747887 0.0160288695524431 GACAT2 other 1 1 1 -1.45064759074796 -2.41587566747887 7.04747276994447e-09 105.201043253229 19.4491136321721 5.40904049628301 9.55504295033415e-08 501.29550914044 164.251282237592 3.05200362707249 0.00238565834218995 SRGAP2 other 5.50971421154259e-05 1 0.00097738534338968 5.40904049628301 3.05200362707249 1.29229962107635e-22 3.69456114408572 0.859955085429851 4.29622570606578 2.06132442138579e-05 -12.1159918494037 1.82590899878241 -6.63559457644557 7.88558468035603e-11 NDUFV2-AS1 other 1.60930071812638e-18 1.12890030283977e-06 0.1810255106861 4.29622570606578 -6.63559457644557 0.796686128855042 7.39917251044659 29.2703810165359 0.25278702406595 0.800530438457875 54.6263491230514 82.6307742621547 0.661089643789899 0.508841011406413 BAHCC1 other 1 1 1 0.25278702406595 0.661089643789899 0.00836143575525082 32.7649545452659 14.5680192437871 2.24910154201226 0.024908965542931 258.950578354639 121.573888726508 2.1299851560821 0.0336251456118002 RASSF5 other 1 1 1 2.24910154201226 2.1299851560821 4.46983246279021e-75 150.166976793616 7.50504623890615 20.0088010137967 1.37429054729925e-66 -186.628352366047 35.0872643538981 -5.31897700783028 1.5483455306005e-07 STRADA other 6.93405109952646e-71 0.00203204867436009 2.1294632030402e-62 20.0088010137967 -5.31897700783028 7.14781194527481e-05 1.09844960027121 1.9370746342498 0.567066224940074 0.570908821299548 -14.6961207984965 3.96137140520803 -3.70985683876434 0.000229225655226484 LINC00683 other 0.396060259887677 1 1 0.567066224940074 -3.70985683876434 4.59686397135575e-06 4.49289276799963 0.963749483507108 4.66188863899556 3.98735195231001e-06 -4.29737987199777 4.49792421137632 -0.955414024346759 0.339812304035241 SNHG25 other 0.0287993527805438 1 0.036926866430343 4.66188863899556 -0.955414024346759 0.000112423444597869 286.100087643899 178.762602539375 1.60044709340636 0.110077850277775 -1695.62033042176 509.156722814079 -3.33025226702333 0.000926281783311024 NCOA4 other 0.6067493304947 1 1 1.60044709340636 -3.33025226702333 5.73711349319186e-10 207.667341231932 31.3250124715681 6.62944161380364 8.50899436909253e-11 73.1424422097841 381.149125845474 0.191899803121778 0.847896184499574 MRPS21 essential 4.7635253333972e-06 1 9.82023040136969e-07 6.62944161380364 0.191899803121778 0.598451857326655 -12.7166805926589 18.1425897292784 -0.700929733980414 0.483648227223702 -44.3267501147427 48.4651673951626 -0.9146104820669 0.360803607647616 GDF10 other 1 1 1 -0.700929733980414 -0.9146104820669 5.7720644294377e-08 74.7147022076938 25.1108777939292 2.97539189274207 0.00305811820518634 -391.804617861244 89.4459117429969 -4.38035244122736 1.42564089925645e-05 MYO15B other 0.000425747472315325 0.170506651551072 1 2.97539189274207 -4.38035244122736 1.89970681424932e-22 13.6008940640856 2.717743482642 5.00448042685169 7.57095783268646e-07 -41.2063062032181 6.25354037892843 -6.58927642684847 1.04377832710843e-10 MIR3661 other 2.36000577534193e-18 1.49145485160523e-06 0.00734080071457279 5.00448042685169 -6.58927642684847 0.0293917785919687 -0.60140912252236 1.56306702536159 -0.384762209658434 0.700563422904042 7.07352692902609 3.16018451056828 2.2383271943049 0.0256019917729748 MIR4444-2 other 1 1 1 -0.384762209658434 2.2383271943049 0.235402266970298 -0.782805075548594 1.21063697827416 -0.646605951739992 0.518165860596891 -4.67680310836851 2.75572463696983 -1.69712279871006 0.0902583332142744 GAPLINC other 1 1 1 -0.646605951739992 -1.69712279871006 0.501831198464692 -4.74441582214445 10.972932736518 -0.432374455951505 0.665639993793119 -67.6849660457011 58.734752947309 -1.15238359998588 0.249667770507619 FXYD1 other 1 1 1 -0.432374455951505 -1.15238359998588 2.96990879253652e-35 127.264677355305 17.3378875979237 7.34026429901097 7.97517443083384e-13 -287.26830789805 38.5719245885488 -7.44760109749186 3.83278614690369e-13 AARSD1 other 4.24607860068946e-31 5.65565923837108e-09 9.71216742186945e-09 7.34026429901097 -7.44760109749186 0.338439477603064 7.89106383735604 6.75543854391778 1.16810534002426 0.243280692765564 -4.34152422285863 14.0853902007108 -0.308228892561282 0.758027249793434 LINC01929 other 1 1 1 1.16810534002426 -0.308228892561282 2.6059488450042e-09 26.5020886725032 4.16895821724308 6.35700510570936 4.36992514657209e-10 40.561433676085 17.868647183234 2.26997787018501 0.0236007714584641 ZNF850 other 2.08710442996387e-05 1 4.93495646802386e-06 6.35700510570936 2.26997787018501 0.142359613199979 6.7189285933475 3.51618459256097 1.91085775404466 0.0565570296570529 2.469883169667 7.82252198704533 0.315740009904389 0.752322986968052 PTGES3L other 1 1 1 1.91085775404466 0.315740009904389 8.60405730864297e-36 45.5797679533845 6.39500606039395 7.1274002749853 3.31347188668773e-12 -120.657107093756 14.984404258468 -8.0521791198719 5.27281837868534e-15 ASB16-AS1 other 1.23451014264409e-31 7.91660951375817e-11 3.98113647185531e-08 7.1274002749853 -8.0521791198719 5.11123079084258e-12 112.550287830979 17.7119018508958 6.35450042454287 4.45444485540586e-10 -114.658458170914 58.5556673553597 -1.95811034780084 0.0507324973521788 ILF3-AS1 other 4.69722109678433e-08 1 5.02817735278213e-06 6.35450042454287 -1.95811034780084 2.09951157751338e-27 50.1921982505191 4.51325617036146 11.1210612373681 8.08285216119469e-26 -29.2760518884188 18.0251638666833 -1.62417674008118 0.104969555714191 TBC1D3P1-DHX40P1 other 2.79927878629859e-23 1 1.16312242599592e-21 11.1210612373681 -1.62417674008118 1.08826621293886e-11 9.39265963364469 2.44659465719751 3.83907469347769 0.000138297682130718 -46.201969726334 9.19020318603123 -5.02730666461861 6.80024962798045e-07 ZNF561-AS1 other 9.84227962981903e-08 0.00870023937403818 1 3.83907469347769 -5.02730666461861 0.491140507214593 0.843451348501854 6.07574203112894 0.138822771635209 0.889641667918888 -21.1753199271565 19.7784215451516 -1.07062739454794 0.28481264872799 PCAT19 other 1 1 1 0.138822771635209 -1.07062739454794 9.71882721571771e-07 6.78997304319747 1.6972661416298 4.00053525882358 7.19985086128105e-05 -14.8450099424236 5.66918244099696 -2.61854510715182 0.00907807471341114 RNF157-AS1 other 0.00649509222826414 1 0.60277151410645 4.00053525882358 -2.61854510715182 8.66790751421313e-24 113.327053373223 14.130860282513 8.01982689712572 6.75936751261229e-15 -106.668862562512 32.7574413568789 -3.25632461340305 0.00120040322609677 CHMP1B-AS1 other 1.09978410540336e-19 1 8.62698075634707e-11 8.01982689712572 -3.25632461340305 6.01613386744409e-08 5.96703376858215 5.72512276777396 1.04225429054026 0.297784716303012 -55.3984639608398 11.7420125539485 -4.71797008445636 3.07576976269706e-06 PARD6G-AS1 other 0.000442727291305211 0.0381764542945959 1 1.04225429054026 -4.71797008445636 0.21410377531347 8.25449202244597 12.3576675134108 0.667965213782296 0.504439083025655 -29.5530523224484 24.1446562109428 -1.22399971506136 0.221482176677646 LINC01140 other 1 1 1 0.667965213782296 -1.22399971506136 1.18593037791623e-15 26.4624680319552 3.56942809366416 7.41364368116195 4.89597679921312e-13 -9.78424506432224 8.66005065675531 -1.12981383736942 0.25906573705199 MAP3K14-AS1 other 1.25091936262604e-11 1 5.9936547975967e-09 7.41364368116195 -1.12981383736942 5.38491239527017e-07 17.9175717415734 3.418517008634 5.24132882659929 2.30583628687943e-07 -4.69839398904708 15.3331913934976 -0.306419835797494 0.759405343856585 CEBPA-AS1 other 0.00367681818349047 1 0.00230721978865155 5.24132882659929 -0.306419835797494 5.81579750996383e-06 4.97189023764587 4.58816545958015 1.08363359635701 0.279004698346665 -57.8124869460405 13.7414961180754 -4.20714647439261 3.02210689584282e-05 DM1-AS other 0.0360695761567957 0.353435401468817 1 1.08363359635701 -4.20714647439261 0.00111205501400892 3.16854472894929 1.39191225356528 2.27639689271598 0.023209948156975 -14.22438341224 5.71526844102254 -2.48883907361928 0.0131139989194829 ZNF582-AS1 other 1 1 1 2.27639689271598 -2.48883907361928 1.62081199010837e-17 18.4679583305118 2.04982009860924 9.00955081035742 3.57656384364801e-18 5.80881035673848 10.0635402951395 0.577213404664761 0.564036311404944 ZNF571-AS1 other 1.80461206978666e-13 1 4.81798915377824e-14 9.00955081035742 0.577213404664761 2.0864362120962e-06 20.0122950741206 4.60152288294133 4.34905912308069 1.63220074630356e-05 -22.1273546543411 15.5638917986823 -1.42171090242445 0.155682179980869 ZNF285 other 0.0135388845802922 1 0.144498732070254 4.34905912308069 -1.42171090242445 1.45544256321722e-07 49.4514373969723 9.01700309123253 5.48424314560291 6.37748565642192e-08 -6.20601459733891 33.1084772470929 -0.187444881593998 0.851381984349224 S1PR2 other 0.00104143638503179 1 0.000658858043164949 5.48424314560291 -0.187444881593998 4.21962656915396e-16 31.0019794185805 11.3052008848564 2.74227585465628 0.00630173450236117 -271.378849928096 38.3341320328651 -7.07930075723208 4.47472434098759e-12 ZNF224 other 4.51331257836707e-12 6.5268329237645e-08 1 2.74227585465628 -7.07930075723208 2.72473264261818e-19 62.0548582601915 7.97366353111608 7.78247765509935 3.59325670438218e-14 -72.3850878495673 25.7703912725775 -2.80884706343566 0.00515031905367734 LUZP6 other 3.17731073455706e-15 1 4.52247288813541e-10 7.78247765509935 -2.80884706343566 0.0348089262396067 1.86685979096693 0.857804223711553 2.17632385031795 0.0299581592537794 -1.58414493221757 2.56730874254134 -0.617044964622932 0.537461815989776 EML2-AS1 other 1 1 1 2.17632385031795 -0.617044964622932 0.00138015878207518 -2.64717491127746 1.21972913429673 -2.17029735278379 0.030415458064264 -21.2554580214345 6.43897533976502 -3.30106218766947 0.00102623510161489 LINC01801 other 1 1 1 -2.17029735278379 -3.30106218766947 1.92232946723666e-14 481.712403446533 72.1055594350431 6.68065551700611 5.91226182955229e-11 -1026.65258117203 367.40943437238 -2.79430108517978 0.00538533861367018 SMIM22 other 1.94270615958937e-10 1 6.85231146045111e-07 6.68065551700611 -2.79430108517978 1.51033235579277e-26 65.8505644708905 5.97078222511928 11.0288002456119 1.14316090401904e-25 -29.717589842492 27.4223250831735 -1.08370058893098 0.278976762146986 LIN37 other 1.99273251023298e-22 1 1.64329379952737e-21 11.0288002456119 -1.08370058893098 7.12440207368498e-07 6.46905842518546 4.05971210892753 1.59347713621359 0.111685115184556 -64.1070768196337 13.9229547696407 -4.604416079798 5.25283430498852e-06 MZF1-AS1 other 0.00482108288326263 0.0644837939280391 1 1.59347713621359 -4.604416079798 0.00632574206746559 2.82250625063072 1.79855877950901 1.56931554463916 0.117152688418059 -11.8894863673644 5.44865123663197 -2.18209715597687 0.0295271180835771 CARD8-AS1 other 1 1 1 1.56931554463916 -2.18209715597687 1.97144889623703e-14 47.815911429782 6.42747850379156 7.43929542534845 4.00896968029552e-13 -27.8196466966656 21.1771084162485 -1.31366597128627 0.189516474335854 PTOV1-AS1 other 1.99096624030978e-10 1 4.91740220985048e-09 7.43929542534845 -1.31366597128627 1.50797541509601e-19 23.2044964578318 6.31870602625444 3.67234942746447 0.000263977437135788 -130.816322639351 17.9643094286711 -7.28201232331078 1.15449756860274e-12 NAPA-AS1 other 1.76930755453215e-15 1.69526422973627e-08 1 3.67234942746447 -7.28201232331078 1.77931545279338e-07 6.02169053246983 1.07217205891582 5.61634719203462 3.11992933033559e-08 7.13982217583613 4.54412258780583 1.57122129473264 0.116714815858474 ZNF649-AS1 other 0.00126455949230025 1 0.00032706219169908 5.61634719203462 1.57122129473264 2.05244782805176e-05 3.17738219160187 0.796232406820186 3.99052106443518 7.49461917402916e-05 -1.09042622978258 1.98342054188994 -0.549770563908521 0.582701965729519 RAET1E-AS1 other 0.121197044246457 1 0.626475216757098 3.99052106443518 -0.549770563908521 0.00232149607850547 5.47729066022476 1.56566216332438 3.49838604299844 0.000506395427868498 6.58327935841555 5.20882078392958 1.26387135044586 0.206817509286719 LINC00664 other 1 1 1 3.49838604299844 1.26387135044586 5.06458352294528e-12 38.8151164813535 6.47366833191869 5.99584570775334 3.83485681327166e-09 -72.4968264431177 24.2846898439255 -2.98528936993 0.00296913704943103 A1BG-AS1 other 4.65587163264359e-08 1 4.1684893560263e-05 5.99584570775334 -2.98528936993 0.0943036253751333 -0.220078885691222 0.464457409213584 -0.473840833035385 0.635807811159213 -9.51695553571439 4.43066337453648 -2.14797531006517 0.0321666382841869 LINC01711 other 1 1 1 -0.473840833035385 -2.14797531006517 1.04476943158795e-07 16.7181560524194 3.73389710930857 4.47740137529264 9.33743178873698e-06 -17.1606567859061 8.67136393469387 -1.97900317817902 0.0483551951465044 MAN1B1-AS1 other 0.000754741437379138 1 0.0843727726120753 4.47740137529264 -1.97900317817902 0.193588140508158 104.61689877444 60.0790623040272 1.74132043281619 0.0821927235240819 155.977046167465 135.31944098625 1.15265807359723 0.24955700103531 MTRNR2L2 other 1 1 1 1.74132043281619 1.15265807359723 0.000138332310120849 -68.2663689715766 16.6854277062738 -4.09137662955492 4.94023101230904e-05 -86.0604945599454 34.3393867380331 -2.50617447587169 0.0124963933289072 TRABD2B other 0.738279539114969 1 0.419623222185529 -4.09137662955492 -2.50617447587169 2.50115801954613e-26 135.584953570513 11.8654151613373 11.4269034607662 2.94679634499712e-27 96.6619441286288 63.1654196563947 1.53029845530114 0.126523071495221 FBXO17 other 3.29177406952467e-22 1 4.27462277805283e-23 11.4269034607662 1.53029845530114 2.2926672588603e-07 21.5028894836049 4.44797784468251 4.83430678714178 1.7427013424753e-06 68.1077239084052 18.8724734268379 3.60883930622212 0.00033606353489632 ZNF350-AS1 other 0.00161426701696354 1 0.0165225514280083 4.83430678714178 3.60883930622212 0.0274397725567614 8.14284974734396 4.93845032636184 1.64886739953154 0.0997531918891444 -26.7425681961357 17.5906615587792 -1.52027074745173 0.129024997188605 ZSCAN16-AS1 other 1 1 1 1.64886739953154 -1.52027074745173 2.34561757099276e-32 174.077918940426 14.2706006646787 12.1983596227514 2.40778570387353e-30 -162.45186041793 71.1017794796672 -2.28477910970409 0.0227193389978143 ZNF587B other 3.27823511721948e-28 1 3.54426055610184e-26 12.1983596227514 -2.28477910970409 1.05607233401646e-18 23.9445514257831 3.73910474975464 6.40381937076096 3.31112766645193e-10 -45.5719018124046 10.1759868080224 -4.47837665989085 9.19320812566644e-06 RAB11B-AS1 other 1.2124766466843e-14 0.11124701152869 3.75581211205643e-06 6.40381937076096 -4.47837665989085 0.328233016157517 -82.865427767121 64.8422498415936 -1.27795423461643 0.201809599887476 104.135966932707 228.997080250246 0.454748011716604 0.649471613171833 SPIB other 1 1 1 -1.27795423461643 0.454748011716604 0.340378588356939 8.53177786003096 7.23685077689672 1.17893516434914 0.238950000308464 -13.4615792395836 27.7689662637117 -0.484770628900763 0.62803821942927 LINC01224 other 1 1 1 1.17893516434914 -0.484770628900763 0.00236546395424502 2.2444504863545 1.34879913475862 1.66403612555413 0.0966768805430884 -9.75999596739265 4.03323460794764 -2.41989294353476 0.0158493798332331 PLA2G4C-AS1 other 1 1 1 1.66403612555413 -2.41989294353476 4.04813956540494e-14 25.9895848898339 13.0906195787478 1.98535941965857 0.0476070975074111 -180.416326359079 27.0130807735959 -6.67885043809694 5.97042203017664e-11 RPARP-AS1 other 4.04085291418721e-10 8.56695857110046e-07 1 1.98535941965857 -6.67885043809694 4.41383022676608e-05 -0.778805564959348 0.749297937038162 -1.03938036722458 0.299087915555145 -9.52320726759966 2.11701180760057 -4.49841953332953 8.36894473464037e-06 NOP53-AS1 other 0.251809014437005 0.101556542177833 1 -1.03938036722458 -4.49841953332953 4.99913133435447e-05 32.3555515032118 7.215697947778 4.48405015528337 8.94113861011894e-06 33.036765444933 27.748815760512 1.19056487779727 0.234344658570373 ZIM2 other 0.282600894331058 1 0.0809173044215764 4.48405015528337 1.19056487779727 0.161866591957783 1.81488359072455 14.5352710346435 0.12486066385683 0.900679900940104 100.130386012907 52.9267914199818 1.89186578907377 0.0590387105715332 KLK9 other 1 1 1 0.12486066385683 1.89186578907377 0.950446208233906 -4.50875692881478 15.3247735472831 -0.294213608762533 0.768706908672514 -7.54990449719888 30.6352195442183 -0.246445255151558 0.805430541854504 KCNQ1OT1 other 1 1 1 -0.294213608762533 -0.246445255151558 0.1912159843592 11.8385583807732 6.64057864198709 1.78276006038394 0.0751849653632675 -2.68473619969948 27.7202266791163 -0.0968511632598619 0.922880394074349 ZNF528-AS1 other 1 1 1 1.78276006038394 -0.0968511632598619 4.92777179460771e-05 15.5089426173273 133.997282726955 0.115740724749843 0.907900583727772 -2171.23200406143 509.246431869809 -4.26361751046399 2.37011899163917e-05 EGLN2 other 0.278813328138904 0.279206250916674 1 0.115740724749843 -4.26361751046399 0.00200577546976813 13.4424866072156 6.19067590094553 2.17140855413904 0.0303301916810922 -20.1855739579095 11.9596779344532 -1.68780246997784 0.0920202333098745 ARHGAP19-SLIT1 other 1 1 1 2.17140855413904 -1.68780246997784 3.67568152806806e-08 -29.1226592276165 61.5308333533543 -0.473301882007242 0.636189088937089 -725.143564081116 129.56482863875 -5.59676242155924 3.47765374532719e-08 SNHG8 other 0.000274683680592526 0.000467118451072348 1 -0.473301882007242 -5.59676242155924 0.00535535580286501 -112.167001068331 76.3328580644758 -1.46944584432549 0.14230634198233 -930.281816067324 296.070192718153 -3.14209886353847 0.0017713560556484 COMMD3-BMI1 other 1 1 1 -1.46944584432549 -3.14209886353847 0.618173902869654 337.384817082181 491.157995612701 0.68691708186753 0.492432615336244 1142.37860665018 1304.33130700741 0.875834690552048 0.381512961555711 RMRP other 1 1 1 0.68691708186753 0.875834690552048 4.65885422582475e-15 140.073021687238 34.9410922048574 4.00883352088708 6.95198965041808e-05 -584.089193556774 104.248580712022 -5.60285031764865 3.35026463858864e-08 C7orf55-LUC7L2 other 4.81772115492538e-11 0.000450175059487156 0.582437692912027 4.00883352088708 -5.60285031764865 1.05537255656498e-12 2.51830476354552 0.994036946119451 2.53341163361839 0.011575519030895 -11.8099713064478 2.0475661561172 -5.76780939222158 1.34823372206977e-08 MKNK1-AS1 other 9.96377230652997e-09 0.000183656397620344 1 2.53341163361839 -5.76780939222158 1.64797511535067e-06 176.17164460529 38.0801664145609 4.62633599568322 4.69184754137311e-06 -681.606042887295 356.133892939174 -1.91390388952312 0.0561748147359422 C8orf44-SGK3 other 0.0107892930802008 1 0.0432447587888359 4.62633599568322 -1.91390388952312 0.788306384649263 -9.49130082838809 23.46793237118 -0.404437028293297 0.686051218336374 -37.5578915541901 55.7456712103786 -0.67373646668367 0.500766611706148 SCARNA2 other 1 1 1 -0.404437028293297 -0.67373646668367 0.000424381995561209 7.75817669698336 1.98266617655243 3.9130019913255 0.000102844541275329 -6.13739293470079 14.9612265013657 -0.410219906378702 0.681807946216531 GAS5-AS1 other 1 1 0.848775999145291 3.9130019913255 -0.410219906378702 4.12199660289795e-09 50.2762102138429 8.00773120391266 6.27845877110329 6.987971239744e-10 -24.5545956861074 48.3244280543627 -0.508119737257617 0.611574966094743 TSNAX-DISC1 other 3.26462130949518e-05 1 7.82513019426533e-06 6.27845877110329 -0.508119737257617 0.0042493250276116 -2.70734278815089 1.38046303116296 -1.96118456418939 0.050368130097121 -14.2995643610888 4.4938345996177 -3.1820406479369 0.00154604480083451 LINC01480 other 1 1 1 -1.96118456418939 -3.1820406479369 8.80657908789991e-38 262.157923066722 23.0480340629329 11.3744158113832 5.28951974246966e-27 -235.374289415813 55.4932373161615 -4.2414950145153 2.61565885282313e-05 BIVM-ERCC5 other 1.27651363879109e-33 0.307261445441134 7.66345620289005e-23 11.3744158113832 -4.2414950145153 0.406597430036152 23.8983972255778 19.003413127133 1.2575844699948 0.209167893189074 -14.4194608013505 69.4816215425065 -0.207529134773131 0.835686721403528 NBPF8 other 1 1 1 1.2575844699948 -0.207529134773131 0.03076913266905 58.6513610751487 22.181556046746 2.644149984408 0.00844699309990133 -0.0161284953545664 252.130528165624 -6.39688318265515e-05 0.999948985770224 HIST2H4B other 1 1 1 2.644149984408 -6.39688318265515e-05 1.14763127403946e-15 2.37961748882383 1.72346211711421 1.38071934694352 0.167946136489378 -35.9689528354522 4.60758393687346 -7.80646719153626 3.15303873518926e-14 POC1B-AS1 other 1.21098052036644e-11 4.70118075416719e-10 1 1.38071934694352 -7.80646719153626 1.17128588993777e-26 30.1159367576417 5.0423484941814 5.97260121794315 4.26956544906981e-09 -55.9611642304529 10.7968380353277 -5.18310676212294 3.10219608481247e-07 HMGN3-AS1 other 1.54738578919678e-22 0.00402168700435089 4.63333242533056e-05 5.97260121794315 -5.18310676212294 0.640685857415594 0.691105416802213 0.739550621821043 0.934493726880331 0.35053014876588 0.154537109684862 2.70399722792573 0.0571513565505423 0.954448966846189 PFN1P2 other 1 1 1 0.934493726880331 0.0571513565505423 0.0152003914714787 46.1784126501233 15.9002907806301 2.90424956922035 0.0038331834193133 40.9301935690619 36.9110070975902 1.10888856163814 0.267975550006952 LINC01235 other 1 1 1 2.90424956922035 1.10888856163814 1.08320417989329e-08 192.005991815148 32.4795831452374 5.91159039685219 5.9857054932067e-09 -48.7221346620076 128.118121893133 -0.380290734379076 0.703878049691963 URGCP-MRPS24 other 8.3569202478767e-05 1 6.46396336211392e-05 5.91159039685219 -0.380290734379076 1.60206685858078e-48 624.846350193022 51.0144608411129 12.248416231216 1.32803466045096e-30 -887.681216672742 150.238441460851 -5.90848259634037 6.12363752109949e-09 TAF15 other 2.41239227565093e-44 8.42122631901602e-05 1.95672626870845e-26 12.248416231216 -5.90848259634037 2.68099185942785e-09 6.21216627356665 1.00508005802265 6.18076761545559 1.28820210810901e-09 -8.14232027071433 8.52214670316406 -0.955430662522071 0.339803049777946 YTHDF3-AS1 other 2.14532968591417e-05 1 1.42771439641722e-05 6.18076761545559 -0.955430662522071 7.51990564048076e-17 295.406828098018 33.2714148775388 8.87869750010073 1.01257182941887e-17 91.5505938444503 85.38143519929 1.07225409868973 0.284087550198971 HSPE1-MOB4 other 8.2245207989938e-13 1 1.35613745114069e-13 8.87869750010073 1.07225409868973 7.5547918967563e-13 473.71339667769 74.7964466549021 6.33336766468762 5.04789487213298e-10 -525.418747115938 256.04459502089 -2.05205951359009 0.040644582365453 RPS10-NUDT3 other 7.16572011407335e-09 1 5.68443441550895e-06 6.33336766468762 -2.05205951359009 0.0892136576201903 7.49302645866711 3.4167066097996 2.19305527643961 0.0287236702867227 6.58627986143291 11.5624611536775 0.569626117994622 0.569165159293808 LINC00221 other 1 1 1 2.19305527643961 0.569626117994622 0.0368457515325498 57.5125119340282 22.3398849715142 2.57443187408364 0.010327675833934 -0.772218125954506 253.340639725746 -0.00304814153303817 0.9975691568669 HIST2H4A other 1 1 1 2.57443187408364 -0.00304814153303817 0.31047559750763 2.9191540265984 18.9195412581254 0.15429306592435 0.877436418617592 78.0825389891935 52.8798517920873 1.47660283346099 0.140366117719635 RASL10B other 1 1 1 0.15429306592435 1.47660283346099 2.7064485443945e-06 27.8224500987583 6.16605117051687 4.51219902808982 7.87294678892978e-06 -37.5865476907423 21.9676095851225 -1.7109985292254 0.0876535548334338 GPR75-ASB3 other 0.0173672803093795 1 0.0715021027370602 4.51219902808982 -1.7109985292254 0.000114724588410213 9.54683971031012 2.3941019599219 3.98764959476562 7.59030402660786e-05 -16.3702672632303 10.2790585949119 -1.59258429281972 0.111837555966908 LPP-AS2 other 0.618594980707867 1 0.634169901423087 3.98764959476562 -1.59258429281972 9.22149104642681e-07 8.48733261928012 2.48460664610087 3.41596631909498 0.000683035585987362 -23.3262299541267 8.29012585285423 -2.81373653044068 0.00507408535905427 CTAGE15 other 0.00618393189573382 1 1 3.41596631909498 -2.81373653044068 3.58852974269574e-19 52.2202049112103 7.61016195559674 6.86190454498882 1.86237429890652e-11 -48.4320874524102 15.0780205452072 -3.21209851831678 0.00139590853582164 TMEM56-RWDD3 other 4.16771844316683e-15 1 2.19126960009341e-07 6.86190454498882 -3.21209851831678 0.000304616916074373 4.09698641055834 1.47701924101549 2.7738206089594 0.0057311670519565 -11.6301408988287 4.79757673100537 -2.42416985718361 0.0156695230127824 TMCC1-AS1 other 1 1 1 2.7738206089594 -2.42416985718361 1.38284244947662e-18 289.109150352096 33.6014787327005 8.60406033472386 8.43713687521485e-17 -150.692062118988 124.492297866081 -1.21045289308653 0.22663568691562 SRXN1 other 1.58266318342599e-14 1 1.11420829574087e-12 8.60406033472386 -1.21045289308653 4.4598578708879e-06 5.83518869525061 1.9971227122973 2.92179777402781 0.00362502553730854 -19.638452169751 6.66272620616381 -2.94751000747759 0.00334115976855121 CTAGE6 other 0.0279856081398216 1 1 2.92179777402781 -2.94751000747759 0.0180316592135199 -8.55081162560061 4.78711940355881 -1.78621231366066 0.0746279278580987 -36.2486334313897 13.3837954810559 -2.7083971421035 0.00697616014690394 MMP28 other 1 1 1 -1.78621231366066 -2.7083971421035 0.00117685039411199 121.692046929689 55.9515769527897 2.17495294247683 0.0300668596441687 561.520685285905 157.146074798049 3.57324028619566 0.000384144396634001 CCL5 other 1 1 1 2.17495294247683 3.57324028619566 0.407401179277923 -2.04450011776018 1.73263943342019 -1.17999168108761 0.238544085299477 3.06825835026045 7.62041100242622 0.402636858994032 0.687381178024986 MILR1 other 1 1 1 -1.17999168108761 0.402636858994032 0.000398593629773857 2.87669593051097 1.2587105996094 2.28543076653494 0.0226815980965965 -8.59967090733801 3.36503378965189 -2.55559719304561 0.0108785513447638 ATP2B1-AS1 other 1 1 1 2.28543076653494 -2.55559719304561 7.60100462180037e-44 208.164899918145 16.0531949469979 12.9671944186458 1.086254720166e-33 -136.892532229323 36.2625194243474 -3.7750419552319 0.000177614390455344 MROH7-TTC4 other 1.13057342744659e-39 1 1.61699877643911e-29 12.9671944186458 -3.7750419552319 2.38620023392341e-09 6.2238170108482 2.53425731147333 2.45587414611419 0.0143753062577627 -32.5229215189861 6.66042748400506 -4.88300812479221 1.38666467553969e-06 BMS1P4 other 1.91683464791068e-05 0.0174927748819332 1 2.45587414611419 -4.88300812479221 0.226686978908404 -1.1002981311859 0.855584123400748 -1.28601980926489 0.198988319035152 -3.78992225538491 2.91486409704179 -1.3002054741527 0.194086248266642 LINC01215 other 1 1 1 -1.28601980926489 -1.3002054741527 3.26787575481474e-11 6.45429854260077 2.18623867158881 2.95223875895957 0.00329198532731971 -20.2413295464843 4.46500845359228 -4.5333239022648 7.15626768355827e-06 SNORD58B other 2.88880216725623e-07 0.0871561841180562 1 2.95223875895957 -4.5333239022648 3.37967875977126e-33 213.540557926348 22.8461146640026 9.34690913824451 2.31873830921966e-19 -167.642917421657 48.4984399681019 -3.45666618414774 0.000589649507497859 GTF2H5 other 4.75791175800598e-29 1 3.16739653039405e-15 9.34690913824451 -3.45666618414774 0.000144898863532873 6.59385227305782 1.99560669248322 3.30418428535775 0.00101568823115423 -6.73746084386503 4.69881977142157 -1.43386236791685 0.152190319286021 FGF14-AS2 other 0.770427257404285 1 1 3.30418428535775 -1.43386236791685 0.00936460204110443 21.6370402417132 7.54555359755157 2.86752190703862 0.00430106601038162 -8.02795783764242 27.9078486763672 -0.287659501480693 0.773719413739134 CASC15 other 1 1 1 2.86752190703862 -0.287659501480693 0.791031744920292 26.5499418821217 43.331983306307 0.612710055167434 0.540346638650866 134.752105482828 493.110885474769 0.273269379062862 0.784758987809849 HIST2H2AA4 other 1 1 1 0.612710055167434 0.273269379062862 6.05347323863782e-12 270.954314310363 65.5688903976793 4.13236082945752 4.16000876211138e-05 -992.132393254714 223.742364541222 -4.43426257378237 1.11940406041078e-05 NUDT3 other 5.54679752856384e-08 0.134742666751645 0.356013549861492 4.13236082945752 -4.43426257378237 1.19224016467139e-29 361.305826170411 31.3181890644124 11.5366129704151 1.06062774185415e-27 -264.503356126119 144.498473680989 -1.8304923878301 0.0677222582946183 KMT2B other 1.62645403264471e-25 1 1.54194061110757e-23 11.5366129704151 -1.8304923878301 1.11579242003619e-11 147.668271548766 29.2103839318394 5.05533483891689 6.02667656245632e-07 -423.547919366454 110.057129683444 -3.84843690349456 0.00013417988432697 POM121C other 1.00867634771272e-07 1 0.00587480431308242 5.05533483891689 -3.84843690349456 1.09381500533493e-60 16519.2194747459 945.031990062144 17.4800637951522 3.05650583594696e-54 -345.437495558358 3172.09194147154 -0.108898954359472 0.913324324165281 CD24 other 1.68250624120618e-56 1 4.70396248152237e-50 17.4800637951522 -0.108898954359472 1.65598502754601e-07 84.8817854156675 31.3740935470802 2.70547371474791 0.00703660957412309 -328.791056906974 87.9897764921198 -3.73669612555977 0.000206350842751019 FAM47E-STBD1 other 0.00117977991131016 1 1 2.70547371474791 -3.73669612555977 0.0010842877594745 3.00436238644326 2.04158170378257 1.47158567343981 0.141709966837363 -11.6087227279166 4.50604074765019 -2.57625782322771 0.0102497183350498 LINC01023 other 1 1 1 1.47158567343981 -2.57625782322771 0.397423142675345 4.59533404028632 27.5962957349612 0.166519959215562 0.867810808891401 63.732012712458 50.4441503407892 1.26341730967613 0.206990555788995 MUSTN1 other 1 1 1 0.166519959215562 1.26341730967613 1.64988094853282e-21 59.7806665132509 9.4880209324636 6.30064656673651 6.24538127955572e-10 -139.940824030755 24.412863012791 -5.73225778383443 1.66662246950511e-08 ZSWIM8-AS1 other 2.01186482864092e-17 0.000226177335336538 7.00731779566152e-06 6.30064656673651 -5.73225778383443 1.43102258334952e-12 21.9129032352683 10.5877696907173 2.06964298198515 0.0390029729661151 -133.422680220853 23.4967131868736 -5.6783550601192 2.31847025994101e-08 ZNF595 other 1.34430261479854e-08 0.000313248516820629 1 2.06964298198515 -5.6783550601192 2.02748389679937e-06 93.1306851368136 41.6260027610448 2.23731991926856 0.0256688657846085 415.845478047357 80.3579017813705 5.17491707509668 3.21053354104799e-07 AFAP1-AS1 other 0.0131745903614023 0.00415988830913588 1 2.23731991926856 5.17491707509668 9.01354116653765e-07 -82.7835963342434 30.3139446552479 -2.73087508985446 0.00652742420389411 -294.525328410938 55.2632046298099 -5.32950143560922 1.46029929678627e-07 DOC2B other 0.00605169153921338 0.00191941739569587 1 -2.73087508985446 -5.32950143560922 0.313003444382662 21.3316444078993 17.1723038798245 1.24221214329672 0.214698500911997 53.1324538803442 41.8067420190103 1.2709063494157 0.20431019244159 PCDHB16 other 1 1 1 1.24221214329672 1.2709063494157 3.03761081555262e-07 6.39274070307322 1.15378147842576 5.54068584269144 4.72966886259257e-08 3.25217948572524 3.32147720183366 0.979136476965681 0.327954270954837 GAS6-AS2 other 0.00211812602168484 1 0.000491932858398253 5.54068584269144 0.979136476965681 3.19282974376157e-06 115.6767097079 70.3824533515614 1.64354472172337 0.100853424650462 -934.21689720573 225.518396471264 -4.14253077276013 3.98730026113796e-05 STAG3L5P-PVRIG2P-PILRB other 0.020341518297505 0.46272619530506 1 1.64354472172337 -4.14253077276013 0.000147867855788913 5.62006648592757 1.34457536527717 4.17980771555269 3.41278898905174e-05 2.66832092973655 3.39274607644789 0.786478230204074 0.431938872052542 JMJD1C-AS1 other 0.785769785662283 1 0.294421306085494 4.17980771555269 0.786478230204074 1.36860530276766e-20 67.0330827256802 22.4632274693856 2.98412518045492 0.00297381385127678 -284.648977490716 41.1399037310985 -6.91904821535944 1.30392331697367e-11 DCP1A other 1.63863112900372e-16 1.89055841728013e-07 1 2.98412518045492 -6.91904821535944 5.71402110419005e-06 2.2978600557193 0.792247606361854 2.90043167977685 0.00387717560798158 -10.219055598175 2.9646204267877 -3.44700303142948 0.000610675463821836 TBC1D8-AS1 other 0.0354665985402699 1 1 2.90043167977685 -3.44700303142948 8.67219294384987e-07 7.72580891524165 1.72739881968504 4.47251024326295 9.41611674057076e-06 -10.1918650632535 5.94365192381488 -1.71474796873904 0.0869609646107175 RBAK-RBAKDN other 0.00582684643897273 1 0.0850463664008351 4.47251024326295 -1.71474796873904 3.54497582434098e-16 81.5435411334481 21.5276749209956 3.78784710530537 0.000169570554161835 -296.852582751936 51.4263487877197 -5.77238302445502 1.33946196881814e-08 ARL2-SNX15 other 3.80056858127597e-12 0.000182488298631784 1 3.78784710530537 -5.77238302445502 1.55199855589395e-08 6.93043446525964 5.22503723548009 1.32638948832732 0.185268309578814 -96.3008857508241 17.1646957404251 -5.61040447247912 3.22021481872351e-08 LINC02035 other 0.000118588209655857 0.000432893478081002 1 1.32638948832732 -5.61040447247912 0.13803811239777 7.64749640951031 3.84589922028983 1.98848070931354 0.0472695082872607 5.03581169181391 11.0357326760367 0.456318745627903 0.648346665738035 FAM95C other 1 1 1 1.98848070931354 0.456318745627903 2.41099162824193e-09 9.65995839582008 5.36693124352873 1.79990351235965 0.0724298001143046 -100.310789415122 17.4364558459475 -5.75293455856949 1.46499509151258e-08 C2orf15 other 1.9353029799898e-05 0.000199268632347541 1 1.79990351235965 -5.75293455856949 1.10129295470825e-08 0.171627232105662 0.817281871646946 0.209997600656194 0.833748314955044 -11.1579763035545 1.99037405829907 -5.60596951966398 3.29914129417169e-08 CDC37L1-AS1 other 8.49317126671004e-05 0.000443371598523733 1 0.209997600656194 -5.60596951966398 8.46840682099535e-06 23.3184975480129 20.553106329095 1.13454857745776 0.257066948919298 -436.631168646476 96.5191109950305 -4.52377942715362 7.47166992104905e-06 C1QTNF3-AMACR other 0.0517927761172076 0.0909078079294039 1 1.13454857745776 -4.52377942715362 1.71501878756022e-10 40.4727295446935 12.5024493589738 3.23718404151293 0.00128066855350684 -177.598380896575 38.6782185551341 -4.5916897812503 5.46679123291846e-06 PAXIP1-AS1 other 1.46479754645518e-06 0.0670392608892791 1 3.23718404151293 -4.5916897812503 0.42358588870439 2.29986981940973 2.56052981843253 0.898200756286306 0.369487926966758 -6.5004511180986 9.81930248233597 -0.662007421585425 0.508255286528965 HIST1H4K other 1 1 1 0.898200756286306 -0.662007421585425 9.86229705399372e-248 195.982124752224 3.07252492777751 63.7853652481139 4.64740581436702e-246 -26.1526994284658 22.2688270874879 -1.17440848257159 0.240776321365506 CWC25 other 1.54650680103675e-243 1 7.28759705750893e-242 63.7853652481139 -1.17440848257159 0.0010737925386301 7.95669136699566 5.2695208613718 1.50994589001861 0.131831262624936 -45.6697516506094 16.0129168607985 -2.85205700170806 0.00456456037614374 SMIM11B other 1 1 1 1.50994589001861 -2.85205700170806 4.49340482085363e-50 64.957314502023 3.84468811325166 16.8953404251782 3.80493777279021e-51 100.432180314876 28.0619596073928 3.57894394119282 0.000378064550814041 EPOP other 6.7967241320232e-46 1 5.83867701234658e-47 16.8953404251782 3.57894394119282 6.86206947614819e-35 232.525452033551 21.8235315450706 10.6548040381701 3.97733039506975e-24 -221.792004163453 60.9094543538919 -3.64133953449677 0.000298161238803302 ZNHIT3 essential 9.78050762435402e-31 1 5.66530941473735e-20 10.6548040381701 -3.64133953449677 0.014968146671864 17.0539149670194 6.10393466305607 2.79392161096315 0.00540055785529036 6.31867367347287 16.8715182905226 0.374517193098283 0.708173132043825 LHX1 other 1 1 1 2.79392161096315 0.374517193098283 2.16295614816148e-30 570.848308184927 83.5059370210879 6.83602062977594 2.25524722762751e-11 -1259.60701092457 185.774822013059 -6.78028915477052 3.21965255723106e-11 CYFIP1 other 2.96908990458126e-26 4.63984130022568e-07 2.64788576995746e-07 6.83602062977594 -6.78028915477052 0.034360416975885 44.6533249099974 20.8706631397204 2.13952592742559 0.0328474814732276 170.479826917751 84.6520076686166 2.0138899432264 0.0445240187424967 HIST1H2BG other 1 1 1 2.13952592742559 2.0138899432264 5.84862643112852e-31 83.479684555632 23.0660868928369 3.61915243549855 0.000323683268057931 -472.213542755133 49.671718689959 -9.50668821633888 6.64002099584433e-20 TAF9 other 8.07636823874537e-27 1.02243043294011e-15 1 3.61915243549855 -9.50668821633888 5.18496558796784e-06 1.19103060305348 1.05568859006859 1.12820259142528 0.259733518139205 -10.4376294937364 2.46484125151752 -4.23460516465729 2.68970812786851e-05 FRMD6-AS1 other 0.0323023356130396 0.315744837130484 1 1.12820259142528 -4.23460516465729 0.121030287875621 -0.344475585785276 3.82327339582783 -0.0900996476373329 0.928242003810923 30.2806404558163 15.5006775821106 1.95350430943505 0.0512845895150992 HIST1H3G other 1 1 1 -0.0900996476373329 1.95350430943505 0.822992116474089 -3302.82460857766 6090.53501030122 -0.542288091767215 0.587845018916626 -6875.66955868583 15313.5945607239 -0.448991223544632 0.653619124215297 RN7SL2 other 1 1 1 -0.542288091767215 -0.448991223544632 5.31858543701336e-08 50.1342078865018 8.55172827492777 5.86246502165964 8.45889592181282e-09 -85.3339505201394 108.34659954082 -0.787601557241211 0.431316128104389 LINC01138 other 0.000393256207212768 1 9.07977888247388e-05 5.86246502165964 -0.787601557241211 0.00109528650554543 29.93339506593 63.5428275309792 0.471074332525359 0.637777895935268 -777.394225912639 217.407037026068 -3.57575466068942 0.000380555920771715 INO80B-WBP1 other 1 1 1 0.471074332525359 -3.57575466068942 0.100583070895157 3.32918697759561 1.9362056096285 1.71943876261901 0.0861509161160789 -6.19942556947804 7.35877897367751 -0.84245301994441 0.399935610008817 CASTOR2 other 1 1 1 1.71943876261901 -0.84245301994441 3.20673136801959e-08 8.13683693216922 14.3137092432473 0.56846459529754 0.569953689203271 -201.150736459692 39.8079194842605 -5.05303314179039 5.94412543586198e-07 NATD1 other 0.000240440717974109 0.00762571852166734 1 0.56846459529754 -5.05303314179039 4.38390021156099e-78 321.327835553465 14.1554083667911 22.7000046362002 3.08748653942027e-79 209.842001516829 100.582167301568 2.08627440774542 0.0374529535822418 SOCS7 other 6.81345770880809e-74 1 4.80690779322342e-75 22.7000046362002 2.08627440774542 0.00714792901310963 3.32851567699085 2.83131771376206 1.17560655973439 0.240288041249788 -18.0136711186827 7.93511861646095 -2.27011995527255 0.023607139800542 TBC1D3H other 1 1 1 1.17560655973439 -2.27011995527255 0.684306044325877 -9.664728443787 90.4118661100104 -0.106896681371749 0.914910500588703 -118.380123360959 147.347123744597 -0.803409800968714 0.422090101508144 SNORA73A other 1 1 1 -0.106896681371749 -0.803409800968714 0.00281879654332038 88.974284199364 26.6190748256893 3.3425009990767 0.000907870714402966 134.861637125687 74.9406772552706 1.79957857421421 0.0726750744340368 CBSL other 1 1 1 3.3425009990767 1.79957857421421 0.0169439427620619 8.18361874085779 2.9079278446944 2.81424408648551 0.00507662040575154 11.4800068519968 11.1289030011657 1.03154882837907 0.302768649967821 ADRA2B other 1 1 1 2.81424408648551 1.03154882837907 0.197526313139376 18.0994298340563 11.2017393386403 1.61576959496124 0.106738088394497 -14.1811996780907 44.3324428285326 -0.319883109824112 0.749182763929774 HIST1H2BE other 1 1 1 1.61576959496124 -0.319883109824112 0.0016636002561975 3.38812421957018 4.68400411962546 0.723339291136468 0.469805034727341 -40.2864773078433 12.7141383494891 -3.16863606486256 0.00162399162717262 ZNF658 other 1 1 1 0.723339291136468 -3.16863606486256 1.29302035675955e-23 15.5414168560604 1.5420197491429 10.0786107731103 5.21660084139568e-22 -2.170131191885 3.7057823019473 -0.585606766685849 0.55838399768903 TMEM269 other 1.63618795944354e-19 1 7.29906789728083e-18 10.0786107731103 -0.585606766685849 0.0288195958446446 3.27975303375542 5.4972386837752 0.596618270084476 0.551029626049618 -32.6176983707187 14.8603060878499 -2.19495467844956 0.0286213031600489 TBC1D3D other 1 1 1 0.596618270084476 -2.19495467844956 5.16605734485926e-20 172.757185423532 23.4131289165292 7.37864580336243 6.67203557561072e-13 -408.994262758708 88.9843722805937 -4.59624822063171 5.44916343948039e-06 RCC1L other 6.12126134792374e-16 0.066833989585227 8.13854899512996e-09 7.37864580336243 -4.59624822063171 0.610962661460686 -97.8685345831658 152.964223823595 -0.639813233034362 0.522567400965338 -324.937326508155 340.713705438708 -0.95369608360709 0.340667389729576 RNU2-1 other 1 1 1 -0.639813233034362 -0.95369608360709 1.62386312382366e-05 4.2851138154593 1.76621371831299 2.42615815460444 0.0155948053136908 -8.74249340381016 3.66832827653609 -2.383236380378 0.017515140911471 RIMBP3B other 0.0969283898610344 1 1 2.42615815460444 -2.383236380378 1.48686980740977e-15 34.0398352635174 8.32291066421249 4.08989554698509 4.97347944178319e-05 -69.3336037834604 16.6703272709213 -4.1591027372571 3.71612218213502e-05 PI4KAP1 other 1.56270016758767e-11 0.432147848560482 0.422298139401811 4.08989554698509 -4.1591027372571 4.65885793850527e-05 4.55614260929639 3.12416901603228 1.45835343283787 0.145366015868777 -29.0778794594313 8.52811799166494 -3.4096478833725 0.00070263398487789 TBC1D3 other 0.264949250962794 1 1 1.45835343283787 -3.4096478833725 8.27899726426261e-05 32.8276317155913 8.95647788288111 3.66523896389407 0.000271893607345381 -47.0330469399058 36.3277309086789 -1.29468716496877 0.195989803738883 HIST1H3E other 0.455096479616516 1 1 3.66523896389407 -1.29468716496877 0.0016737327933508 35.2392530122608 16.1650601273027 2.17996423983243 0.0296865177168609 -136.007628828624 55.531403008732 -2.44920209934616 0.0146305308568996 NPHP3-ACAD11 other 1 1 1 2.17996423983243 -2.44920209934616 2.07881299902514e-05 4.47042826844224 1.62476042903181 2.75143842043603 0.00613196973420576 -5.90957551171019 3.33612035431049 -1.77139158186383 0.077057478892645 PANO1 other 0.122670755072473 1 1 2.75143842043603 -1.77139158186383 0.0063920686396703 2.99100883736015 2.90359088180851 1.03010684325376 0.303436903012688 -19.6151431723921 8.13767312260075 -2.41041178195213 0.0162792140588772 TBC1D3I other 1 1 1 1.03010684325376 -2.41041178195213 0.193682918230588 5.39563663697511 2.97354336436183 1.8145478225212 0.0701410652085887 5.73123504432949 6.95260096460239 0.824329639153575 0.41011157735742 ZNF280B other 1 1 1 1.8145478225212 0.824329639153575 1.09452411567502e-162 1466.70389770282 36.4938133235035 40.1904806357466 2.5218832905014e-160 -641.996486050334 266.186404936369 -2.41183048474546 0.0162241587541384 MLLT6 other 1.71490038443963e-158 1 3.9512867395576e-156 40.1904806357466 -2.41183048474546 4.18792218367205e-19 595.935565246942 65.9539395114955 9.03563258936295 2.83877500967191e-18 -438.716907830985 233.833026878369 -1.87619736051738 0.0611633609860769 PPP4R3B other 4.85757094084121e-15 1 3.82865585554451e-14 9.03563258936295 -1.87619736051738 1.96492390698248e-31 187.150912544755 23.8694809105333 7.84059415645558 2.63048993101922e-14 -403.132649013451 63.2927111768049 -6.36933766176205 4.23672406827415e-10 SYNRG other 2.7257424437661e-27 5.98352540162358e-06 3.31836304798075e-10 7.84059415645558 -6.36933766176205 2.08737417216648e-22 51.2843913744998 13.4299570687998 3.81865638972463 0.000150047970346092 -138.949775054034 27.1797300359569 -5.11225736496328 4.453133606856e-07 NUDT18 other 2.59105755991025e-18 0.00574231578604081 1 3.81865638972463 -5.11225736496328 9.03461400697331e-09 13.2963325009983 3.33224592649997 3.99020144199385 7.61965518677948e-05 -48.9740424822632 12.5617006478685 -3.89867931541364 0.000110309974519425 ZNF2 other 7.0063431624078e-05 1 0.63646979775169 3.99020144199385 -3.89867931541364 0.0522082802652167 17.8785064927654 9.27429245287681 1.92774883729482 0.0544183625072046 -40.2710858634403 36.4844020780956 -1.10378911451637 0.270183636069514 LENG9 other 1 1 1 1.92774883729482 -1.10378911451637 0.125345222645725 3.40971339587596 7.50927455938091 0.454066949998038 0.649965478351466 42.8422924338214 21.1940187965515 2.02143316211422 0.0437342042362857 CCL4 other 1 1 1 0.454066949998038 2.02143316211422 8.67846998280979e-17 -39.5368537394117 71.4325995393366 -0.553484739382045 0.580166708033034 -1058.47135037637 145.919484906119 -7.25380404856393 1.45961731514668e-12 PRAG1 other 9.47254998623688e-13 2.14082071612564e-08 1 -0.553484739382045 -7.25380404856393 9.76195358138563e-06 31.2326707957197 19.500935634797 1.60159857868506 0.109835763565729 267.064879407963 55.0234012036531 4.85365996223134 1.5935475546947e-06 CCL18 other 0.0594307734034757 0.0200468282380593 1 1.60159857868506 4.85365996223134 0.0479202696908861 -69.3737565822884 84.7868550024427 -0.81821358488046 0.413590871927267 -1242.43671270198 506.492978338605 -2.453018631724 0.0144767897526182 FCGBP other 1 1 1 -0.81821358488046 -2.453018631724 0.0079967860053867 0.910198284397208 1.8315624978772 0.496951802328416 0.619439309867135 -11.8072030953045 4.26834818973088 -2.76622303768731 0.00587877848576679 STPG3-AS1 other 1 1 1 0.496951802328416 -2.76622303768731 0.0114190254148511 -62.7625544706601 32.3949556310328 -1.93741751603254 0.0532193141223657 -258.404653442792 91.0837627678531 -2.83700020278469 0.00472629831782686 CCL15 other 1 1 1 -1.93741751603254 -2.83700020278469 1.55822383859398e-75 503.047450680841 25.6985914613245 19.5749036066008 2.97088517338488e-64 -116.568781349056 71.0404450368056 -1.64087909765574 0.101430700972337 AATF essential 2.41758428557855e-71 1 4.59922733691714e-60 19.5749036066008 -1.64087909765574 0.0562414004220155 20.5839391957205 8.63370257072646 2.38413809453115 0.017469410314684 33.6877333177788 35.0123727583919 0.962166533249433 0.336403895245167 HIST1H2BH other 1 1 1 2.38413809453115 0.962166533249433 0.700215990495741 0.498777088034406 1.31196926183435 0.380174370348458 0.703963286820202 1.96987147973875 2.33488283816169 0.843670375036752 0.399221742687904 HNRNPCL2 other 1 1 1 0.380174370348458 0.843670375036752 1.33477949351959e-05 5.04620160874674 2.48370938542365 2.03171982936562 0.0426710977929305 -12.8603830521867 4.96908381417686 -2.58807931866552 0.00991114064742903 RIMBP3 other 0.080313682125074 1 1 2.03171982936562 -2.58807931866552 8.75652490005859e-18 90.8188775943163 9.87538798539413 9.196487037131 9.64083017529612e-19 48.7222695175991 70.2000688658516 0.69404874246925 0.487970148397109 ARHGAP23 other 9.83182615778578e-14 1 1.30768220497717e-14 9.196487037131 0.69404874246925 3.09666756137126e-35 122.573599244724 11.5374312603956 10.6239938924257 4.98997076797245e-24 -90.1660601475207 25.6984230830135 -3.50862229391499 0.000488803568932833 TUBGCP5 essential 4.42637661222408e-31 1 7.10521937651598e-20 10.6239938924257 -3.50862229391499 0.000650803515417322 86.1871839795905 22.3843874773087 3.85032577134217 0.00013715397368993 49.8855948483868 63.0187626158592 0.791599085378308 0.429060144750477 U2AF1L5 other 1 1 1 3.85032577134217 0.791599085378308 0.446608085135312 4.13358820100777 19.8508594405751 0.208232203415774 0.835125033396166 -82.4082627262637 71.9500066057172 -1.14535448450835 0.252562290422927 PRSS2 other 1 1 1 0.208232203415774 -1.14535448450835 0.00508420240659948 2.45287954301326 2.18651167492693 1.12182320869393 0.262454372548338 -14.7745964331782 6.12122747064067 -2.41366564206963 0.0161368655519175 TBC1D3F other 1 1 1 1.12182320869393 -2.41366564206963 0.428416803646829 -2.38253362411779 5.25287832170647 -0.453567259358064 0.650322537912158 -14.3795342597756 11.0609306346247 -1.30002933159733 0.194145538518523 SNORA24 other 1 1 1 -0.453567259358064 -1.30002933159733 1.22083043187062e-36 165.238180510565 13.7636285776119 12.0054228126544 2.00996728437413e-29 -44.7617240630444 34.0925467131953 -1.3129475025613 0.189789943010133 DUSP14 other 1.7578737388505e-32 1 2.94721502907779e-25 12.0054228126544 -1.3129475025613 8.5957790412005e-09 193.593517765226 31.6648614407262 6.11382804019578 1.85546471939952e-09 93.8269074344418 86.1322241588088 1.08933570856647 0.276487306196157 UHRF1 other 6.67548200339631e-05 1 2.04268110958693e-05 6.11382804019578 1.08933570856647 0.83826121927914 -3267.93826233693 5996.4031658131 -0.544983079351338 0.585994834903926 -5692.28768775581 14884.0234401434 -0.382442805915184 0.702286547179075 RN7SL1 other 1 1 1 -0.544983079351338 -0.382442805915184 3.82328590968448e-13 119.658937835858 15.4549922619997 7.74241331262728 4.95180883950628e-14 169.970636875887 60.0258274571773 2.83162505335132 0.00480658281694765 HIST1H4I other 3.67150145907e-09 1 6.21154900827667e-10 7.74241331262728 2.83162505335132 0.2854988409945 4.52572448551028 2.88528562899642 1.56855336609583 0.117334571311218 4.59424657660692 5.15851135617316 0.890614803262769 0.373530288468442 PIK3R6 other 1 1 1 1.56855336609583 0.890614803262769 1.8767382550402e-37 97.8287696960157 8.16169095384307 11.9863359503892 2.40606404308853e-29 -33.7373251642613 20.2165314570583 -1.66879888550231 0.0957697695832963 TADA2A essential 2.71620327651969e-33 1 3.52632746155055e-25 11.9863359503892 -1.66879888550231 0.202321953289179 -0.503236164522125 2.17232839248112 -0.231657499972808 0.816920182207345 -11.6851800480913 6.60122900321846 -1.77015220080899 0.0774485393239979 KCNE1B other 1 1 1 -0.231657499972808 -1.77015220080899 1.2338725148204e-217 911.638299086531 16.8035840840508 54.2526103078101 6.94497353723273e-215 -402.712893277031 122.412568954864 -3.2898001954809 0.00107134254616726 PIP4K2B other 1.93471210323839e-213 1 1.08897185063809e-210 54.2526103078101 -3.2898001954809 0.00943651646879057 -72.2001048678071 33.775706861174 -2.1376341630559 0.0329982000733755 -267.796022275892 94.9659726686788 -2.81991554185613 0.00498144161076235 CCL14 other 1 1 1 -2.1376341630559 -2.81991554185613 0.0298527172339217 23.0619893434583 84.2400293790516 0.273765210119849 0.784369936652939 -492.185217848446 208.104601161184 -2.36508570739017 0.0183790927972078 PCDHGB5 other 1 1 1 0.273765210119849 -2.36508570739017 8.55772383952583e-07 80.9021449610325 27.0208021894716 2.99406895449445 0.00288335717952572 -153.50562155797 58.2074136402439 -2.6372177005961 0.00860808347068329 HERC2P2 other 0.00575335773731322 1 1 2.99406895449445 -2.6372177005961 0.271033709750527 1.21209322269255 9.74150097964536 0.124425714807727 0.901024602512487 143.568285048362 89.2039023882545 1.60943951110445 0.108105761361974 RAB7B other 1 1 1 0.124425714807727 1.60943951110445 0.000173797173698113 -72.8349608871957 75.7377666723761 -0.96167294187935 0.336675977192071 -579.026673863026 142.223596913231 -4.07124194880461 5.430372210385e-05 DACH1 other 0.914173133652074 0.625090145137417 1 -0.96167294187935 -4.07124194880461 0.0101789572511919 14.0534954140518 4.71496101666438 2.98061752035312 0.0030085111054611 4.62044833098438 18.5459896103308 0.249134633851547 0.803352975540862 HIST1H4E other 1 1 1 2.98061752035312 0.249134633851547 9.30388192337742e-11 351.734206564645 85.0645166509044 4.13491101122839 4.16190678291441e-05 -1439.20718411823 323.297780681888 -4.45164572760972 1.05083742850112e-05 GTF2IP1 other 8.03297165264406e-07 0.126709977128664 0.356134363413986 4.13491101122839 -4.45164572760972 0.178993326260463 12.9745482553309 12.8633271811985 1.00864636905878 0.313602791695174 92.6931833287176 52.1740235993922 1.77661558250603 0.0762028917303185 HIST1H2AE other 1 1 1 1.00864636905878 1.77661558250603 0.551347033511147 0.647562012174051 14.8355910374448 0.0436492223693423 0.965201581489461 -183.438181128557 168.01734175836 -1.09178123644151 0.275459303989476 LINC00869 other 1 1 1 0.0436492223693423 -1.09178123644151 0.0159190821498826 6.54057138111705 6.42280653792025 1.018335418092 0.308986732589749 -58.6562048282018 24.1149061501814 -2.43236297346156 0.0153331520967191 TYW1B other 1 1 1 1.018335418092 -2.43236297346156 3.24739576308623e-43 115.292479897579 7.65796279474536 15.0552415815717 8.15566951360223e-43 59.0764686258604 21.4124611779067 2.75897609971223 0.00600142525431651 PIGW other 4.8204342707252e-39 1 1.23876464242104e-38 15.0552415815717 2.75897609971223 0.621177343339007 -1.74156208232703 6.73645638477146 -0.25852792371135 0.796101210583043 -16.7932562656285 17.3801786055153 -0.966230361999818 0.334375498039992 SNORD22 other 1 1 1 -0.25852792371135 -0.966230361999818 0.837559820550732 -490.259324963558 865.742882035763 -0.566287445310241 0.571430223032935 -878.586546419153 2418.25655595518 -0.363314034755971 0.716510415470384 RPPH1 other 1 1 1 -0.566287445310241 -0.363314034755971 0.0557604344579191 7.77751796319209 3.26653362294431 2.38096981722838 0.0176187387869836 13.0818994684498 12.8363525422507 1.01912902636406 0.308605814349634 HIST1H2BF other 1 1 1 2.38096981722838 1.01912902636406 6.31107075194788e-18 6.68630320014024 1.02986692265233 6.49239533096205 1.9168321766912e-10 -4.94298622866509 1.98200021361527 -2.49393829259424 0.0129314526039387 GTSE1-AS1 other 7.11194563037007e-14 1 2.18844729612835e-06 6.49239533096205 -2.49393829259424 1.00290286579899e-153 779.440176961719 20.6061303077236 37.8256453454325 1.6598063914568e-150 -499.680365137484 150.173547454736 -3.3273527435855 0.000939655683996795 PCGF2 other 1.57084675870095e-149 1 2.59975475093879e-146 37.8256453454325 -3.3273527435855 1.52943768730937e-178 441.952761247546 9.89641286079351 44.6578742686074 3.42387844368528e-178 28.6216070006301 71.4991093630985 0.400307182223476 0.689098231265634 SRCIN1 other 2.39678179978251e-174 1 5.3655599090992e-174 44.6578742686074 0.400307182223476 0.000212902394380003 334.634693905403 132.281237441202 2.52972152648742 0.0116996494883544 -721.140833066386 379.956813669491 -1.89795473359685 0.0582370319484446 MARCKS other 1 1 1 2.52972152648742 -1.89795473359685 2.62692053343182e-07 5.64121995182465 1.26756690808924 4.45043170173034 1.04521909782188e-05 36.7392171113812 9.70461913939791 3.78574538409557 0.000170763494115822 CEBPB-AS1 other 0.00184068321777567 1 0.094017457849078 4.45043170173034 3.78574538409557 3.854843089275e-08 16.3032625719404 2.80110980567964 5.82028685161977 1.0091742027948e-08 -14.7294260385947 17.7952475603118 -0.827716837805915 0.408197198418181 ZNF670 other 0.0002876483913217 1 0.000107991731441072 5.82028685161977 -0.827716837805915 0.223664382500575 2.44514249012418 6.28489871536617 0.389050420835895 0.697398723502186 -73.9848495814486 45.1897862249722 -1.63720291158545 0.102195399121586 GPIHBP1 other 1 1 1 0.389050420835895 -1.63720291158545 0.346814504991118 -5.40290627374469 3.86313471031087 -1.3985808621491 0.162510631328344 -9.48540762637068 7.79387824301847 -1.21703307783483 0.224121284698251 NEFL other 1 1 1 -1.3985808621491 -1.21703307783483 0.474586922454306 9.06242156823058 7.97943046287753 1.13572285771415 0.25658203500397 -0.302802771789151 22.5145814517803 -0.0134491850287187 0.98927444950677 CCL3 other 1 1 1 1.13572285771415 -0.0134491850287187 0.013569814166167 -0.642049307940685 1.34860240564015 -0.476084949319011 0.634239890349628 -11.6414486459622 3.99249187136795 -2.91583527807497 0.00372068030085581 PGM5P2 other 1 1 1 -0.476084949319011 -2.91583527807497 9.46525753250411e-129 908.505060662919 27.8023531826489 32.6772721249332 1.46707105049754e-127 -230.60357461779 202.537593114364 -1.1385717143759 0.255412216514292 PSMB3 essential 1.48150210898754e-124 1 2.29625960823875e-123 32.6772721249332 -1.1385717143759 0.864134442482778 0.732397361556489 2.09792527746971 0.349105551766757 0.727144659153765 -2.17804620045303 6.59728628366841 -0.330142744577386 0.741418738277894 SRD5A2 other 1 1 1 0.349105551766757 -0.330142744577386 0.535064162604215 -17.3256941347012 45.8113148202216 -0.378196831998662 0.705434391931295 -138.876110656318 124.498654459105 -1.11548282396848 0.265144367989468 SNORD3D other 1 1 1 -0.378196831998662 -1.11548282396848 2.00780972965125e-143 635.248340335378 18.0539809844101 35.1860534739636 7.24595723832365e-139 -584.625501112082 131.573969960435 -4.44332189176844 1.085996061347e-05 CISD3 other 3.14423003663386e-139 0.130819085549859 1.1346444439491e-134 35.1860534739636 -4.44332189176844 7.59538908238307e-07 6.0969393759766 1.45432338868014 4.19228585844985 3.22224115461145e-05 -3.13085362758279 2.60153314872535 -1.20346482193271 0.229318978865061 SNORA67 other 0.00513064837928195 1 0.278788304696983 4.19228585844985 -1.20346482193271 2.57611482345976e-30 12.3644947951754 1.02655453789149 12.0446545592909 9.26676267386006e-30 4.20554957911037 2.88207094106741 1.4592109858173 0.145088485036098 RDM1 other 3.53391431482209e-26 1 1.36073143102961e-25 12.0446545592909 1.4592109858173 8.93512095881703e-56 236.876769177992 14.6397913889988 16.1803377441563 8.84820996823726e-48 -62.0642081107682 39.5358315239167 -1.56982174696954 0.117080443050999 DDX52 essential 1.3641249167826e-51 1 1.35218344734602e-43 16.1803377441563 -1.56982174696954 3.93442718081133e-25 81.275927178842 7.61416337607648 10.6743082810922 3.57405078075862e-24 -40.4018884899936 32.3065840983925 -1.25057754069406 0.21165433783951 ZNF8 other 5.08878811566137e-21 1 5.09266495750295e-20 10.6743082810922 -1.25057754069406 7.60296751093712e-08 4.77928684321995 1.72229237258517 2.77495674909494 0.00571111477194096 -9.719320761134 3.29844744921986 -2.94663501867607 0.003350476120662 TSC22D1-AS1 other 0.000554636479922863 1 1 2.77495674909494 -2.94663501867607 0.00832493642904227 -3.60022975392307 2.69443544124496 -1.33617220840132 0.182142305104593 -24.0736669452999 7.80156142921642 -3.08574984171057 0.00215072932790605 GLIDR other 1 1 1 -1.33617220840132 -3.08574984171057 0.0881042532823708 236.911380485981 109.516784934744 2.16324265387397 0.0309557191086909 157.015296382395 256.529397910878 0.61207525399075 0.540742764335566 MIR650 other 1 1 1 2.16324265387397 0.61207525399075 3.97762715577101e-42 388.299220341098 26.8085351888137 14.4841640024824 3.22052931633613e-40 104.590386952571 74.9594551909944 1.39529278442696 0.163519739135566 MYO19 other 5.8781374107984e-38 1 4.86944032630023e-36 14.4841640024824 1.39529278442696 0.00349063781609614 3.60474624072912 1.62792469442071 2.21432001927574 0.0272220874368721 -2.98106207228213 2.65647772396696 -1.12218598536955 0.262280251846251 SNORA61 other 1 1 1 2.21432001927574 -1.12218598536955 0.00137297053539057 3.8797040625785 2.85631324718706 1.35829081995796 0.174977897297713 -20.3961737147032 7.72127454848493 -2.64155530108761 0.00850847818252779 TBC1D3C other 1 1 1 1.35829081995796 -2.64155530108761 4.01732843898595e-64 352.900531333286 22.6083597382008 15.6092938815459 2.42153198347745e-45 -333.418369945715 63.2930133795084 -5.26785425662262 2.02336040141594e-07 GGNBP2 other 6.19833604851143e-60 0.0026404853238478 3.69065689601799e-41 15.6092938815459 -5.26785425662262 1.76797206494974e-07 60.5030151278164 11.0005484553641 5.49999987485293 5.84260773574591e-08 13.3018059108932 36.8533641563232 0.360938715241033 0.718284867677467 ZNF229 other 0.00125685134097277 1 0.000604651474572345 5.49999987485293 0.360938715241033 2.56671414400056e-28 88.9481734330729 7.87511541664777 11.2948406121184 1.31489493823887e-26 13.285866279656 22.1095839982808 0.600909826285699 0.548161878803232 DHRS11 other 3.45556725206795e-24 1 1.90120659119958e-22 11.2948406121184 0.600909826285699 1.09452605803164e-16 558.674074028041 98.5318431982052 5.66998501087837 2.38443091877841e-08 -984.834782289027 257.1461895887 -3.82986340907579 0.000144049323284796 ACACA other 1.19150106677324e-12 1 0.000251319018839244 5.66998501087837 -3.82986340907579 4.45728129490581e-07 5.2993162028835 1.91579933934208 2.76611234488857 0.00586716684427742 -9.7192048840449 3.83723955004979 -2.53286373114725 0.0115954946954273 TMEM191B other 0.00306794671528367 1 1 2.76611234488857 -2.53286373114725 0.0008215187237026 0.752532027221584 2.04253181755949 0.368430993706988 0.71269735675205 -15.9733533789762 4.50744315779854 -3.54377256013533 0.00042889461397599 NR2E3 other 1 1 1 0.368430993706988 -3.54377256013533 5.26224974410417e-05 8.42734070726825 4.64791011460443 1.81314623120363 0.0704028086461402 -39.300336610454 12.5643747606758 -3.12791820994205 0.00186210804893703 TBC1D3E other 0.296369905587947 1 1 1.81314623120363 -3.12791820994205 1.09303824204542e-12 194.604077824507 35.3154148415915 5.51045708219514 5.65412109601345e-08 -228.478023986772 88.0930883343063 -2.59359761709926 0.00976698079990081 C11orf98 other 1.03128158136985e-08 1 0.000585823486757953 5.51045708219514 -2.59359761709926 4.87095162282238e-31 53.6241583716241 5.71502939609294 9.38300657005966 1.99305023819352e-19 -68.8881853412884 16.1505337208544 -4.2653813509789 2.37181827001187e-05 MRM1 other 6.72921966692912e-27 0.279376474024698 2.725097590682e-15 9.38300657005966 -4.2653813509789 3.86130647147284e-05 9.85483298333084 2.16631993287991 4.54911245276214 6.67631820300633e-06 6.91645857694961 4.65046142979099 1.48726286227052 0.137536719231508 GOLGA6L10 other 0.221523152268397 1 0.0609614615116508 4.54911245276214 1.48726286227052 0.000147940020531124 6.0352979657896 1.61096014258735 3.74639806798469 0.000198880139792219 18.0260052291895 6.02218994576939 2.99326414336247 0.00288762707258426 HIST1H2AM other 0.786005329081861 1 1 3.74639806798469 2.99326414336247 3.67116815125336e-40 46.9495256523183 3.1979284922924 14.6812306045852 2.86019923833868e-41 12.8658159480724 31.2221650496627 0.412073151480937 0.680450245683207 NKILA other 5.38083115929205e-36 1 4.33234378631159e-37 14.6812306045852 0.412073151480937 0.984167692384747 22.106508915666 212.936764541244 0.103817248107872 0.917357117329354 85.9220476805387 496.36173169173 0.17310369070495 0.862641845513836 MIR6723 other 1 1 1 0.103817248107872 0.17310369070495 0.0868814295157811 42.8712845683107 20.8536993299295 2.05581196362514 0.0402917666042327 110.064404379218 79.9542345977262 1.3765925586429 0.169221700485947 HIST1H3H other 1 1 1 2.05581196362514 1.3765925586429 2.988096706803e-190 402.672392508701 8.53523109173754 47.1776789849902 5.7240615300109e-188 -116.540894413359 52.4704652374393 -2.22107606414367 0.0267851008284 MRPL45 essential 4.68414039758438e-186 1 8.97246644829209e-184 47.1776789849902 -2.22107606414367 5.45496972871287e-07 3.07951161681589 0.594925805706289 5.17629524098375 3.20181806820809e-07 -0.366948547626937 1.60196099806951 -0.229062098308973 0.818907700065246 CEP83-AS1 other 0.00372247134287366 1 0.00317844479631017 5.17629524098375 -0.229062098308973 1.8288485952816e-14 2.45874373479444 1.33035035139512 1.84819264505473 0.0651160298118805 -19.8399815753313 2.97381518547152 -6.67155836457453 6.23150033452607e-11 EPB41L4A-AS2 other 1.84988035412734e-10 8.93846407984419e-07 1 1.84819264505473 -6.67155836457453 2.55493125445906e-26 70.1588964565408 14.0689689306837 4.98678309705611 8.34663763852042e-07 -301.319507266582 37.4391578104478 -8.04824480273153 5.60712017829003e-15 HEIH other 3.36177854461723e-22 8.41684809963117e-11 0.00807286792397695 4.98678309705611 -8.04824480273153 5.07232233833869e-06 -2.21742630044498 2.24229915842925 -0.988907431066559 0.323156301049464 -21.5795445086468 4.47031277306854 -4.82730081855861 1.80944472036237e-06 PWAR5 other 0.0316310021018801 0.0227031029063867 1 -0.988907431066559 -4.82730081855861 1.5892032151748e-17 2.30273671628638 0.253261638146236 9.0923233899196 1.96862187567956e-18 -1.02272457190668 2.83459888309859 -0.360800456814091 0.718393198832244 RBM12B-AS1 other 1.77069022234776e-13 1 2.65980501623065e-14 9.0923233899196 -0.360800456814091 1.79060499402793e-15 3.30292152268406 0.778511059636925 4.24261348865673 2.59921612134962e-05 -9.84345480644562 1.77442763795131 -5.54739714143009 4.54283386131482e-08 MIR3911 other 1.87691215474008e-11 0.000608240025691442 0.226339739847125 4.24261348865673 -5.54739714143009 3.62665406842818e-10 1.09805127025407 2.79557204122258 0.392782319347371 0.694636713266402 -39.9997391328994 6.62266511904357 -6.03982511781843 2.88971071153801e-09 MAPT-IT1 other 3.04131210178387e-06 4.00542801726283e-05 1 0.392782319347371 -6.03982511781843 0.387948143174693 11.2639723747852 8.71316628702715 1.2927530594195 0.19676129912923 22.4673705906309 27.0339455940392 0.831079966203113 0.406370178525552 LINC01667 other 1 1 1 1.2927530594195 0.831079966203113 0.0619535085741391 2.94842697949735 1.31202445705158 2.24723477039684 0.0251681089223571 -0.200437258064937 3.68140759183278 -0.0544458208076737 0.956607088015324 LINC01670 other 1 1 1 2.24723477039684 -0.0544458208076737 1.94701062666718e-46 25.6798790723481 1.58997977624647 16.1510727721151 1.30638004726614e-47 15.5490103184403 12.0295081150764 1.29257241191375 0.196750073531731 UCKL1-AS1 other 2.91740072299811e-42 1 1.99588743621321e-43 16.1510727721151 1.29257241191375 6.80452571194598e-08 69.6993331147192 13.4221584848367 5.19285576857552 2.92741715399196e-07 -31.3081459620086 30.8151413790212 -1.01599877725445 0.310079962556399 THRIL other 0.000498159327371565 1 0.0029130728099374 5.19285576857552 -1.01599877725445 0.00102544027534093 10.7482468032506 5.47828062994907 1.96197448237523 0.0502748921380593 -25.8802208520689 11.5392535648894 -2.24279852301842 0.0253116792799078 CCDC163 other 1 1 1 1.96197448237523 -2.24279852301842 6.5544049791056e-11 0.105686585861911 0.96716142413943 0.109275021960217 0.913024579747449 -11.6900183364597 1.86800558573433 -6.25802108180755 7.89774697833552e-10 EIF1B-AS1 other 5.70823129630307e-07 1.10915958563744e-05 1 0.109275021960217 -6.25802108180755 2.12212326622261e-26 326.1955917659 31.8335778197566 10.2469032420056 1.29139512247899e-22 -520.017236396907 196.725273724339 -2.64336771047313 0.00844975283038002 PAGR1 other 2.79419970463532e-22 1 1.81660551879119e-18 10.2469032420056 -2.64336771047313 1.05723674034411e-15 45.917039086385 5.48315698819509 8.37419741678773 4.8279286967698e-16 -5.31307381467955 24.4122143367632 -0.217639978962433 0.827791996614647 LINC00294 other 1.11718206352163e-11 1 6.28644595606396e-12 8.37419741678773 -0.217639978962433 2.77334084340598e-22 192.565367864974 22.6578211215048 8.49884756492356 1.91272132789334e-16 -82.7172598599137 50.4876438782361 -1.6383664101935 0.101933214645954 CTBP1-AS other 3.43422796638962e-18 1 2.50853402153211e-12 8.49884756492356 -1.6383664101935 4.17660036902982e-08 3.66308642243608 0.822402672725004 4.45412757511909 1.02288242294645e-05 -8.96132368841691 3.873142752311 -2.31370859828751 0.0210555371968748 LINC00921 other 0.00031059353832834 1 0.0921105621863275 4.45412757511909 -2.31370859828751 2.3070385563407e-09 1.53240002719632 1.71944808371731 0.891216223221691 0.373216064943233 -17.3906832094556 3.40827441600786 -5.10248914458757 4.67225682271758e-07 N4BP2L2-IT2 other 1.85462829544229e-05 0.00601926846470706 1 0.891216223221691 -5.10248914458757 0.889201530035995 -0.138204332038023 1.43548227615863 -0.0962772820907687 0.923335615829689 2.40850890017658 5.52256656330765 0.436121298415649 0.662920793958249 TRG-AS1 other 1 1 1 -0.0962772820907687 0.436121298415649 0.00279470453641696 1.49466171835529 1.32876443824438 1.12485078267906 0.26115107932246 -7.39791153330659 2.62836327965554 -2.81464574953129 0.0050609513113727 NPTN-IT1 other 1 1 1 1.12485078267906 -2.81464574953129 1.55151369215559e-05 2.92535545023698 0.849295633447406 3.4444489469027 0.000616683136913777 -5.28772147283996 2.64572989916887 -1.99858703433825 0.0461538988295166 GHET1 other 0.0927805187909042 1 1 3.4444489469027 -1.99858703433825 4.78019637155338e-17 15.2559707354202 2.65173266583215 5.75320843311054 1.47219565409383e-08 -28.5291716188483 5.93770855583803 -4.80474434717716 2.01345446603859e-06 SLFNL1-AS1 other 5.26012808725734e-13 0.0252084499148031 0.00015658272976942 5.75320843311054 -4.80474434717716 0.000137367523430179 2.7493891931476 1.24108426269602 2.21531226830246 0.0271670018743546 -4.8316164110862 2.28249731027982 -2.11681143689666 0.034745629942113 RASSF1-AS1 other 0.733542575117158 1 1 2.21531226830246 -2.11681143689666 2.21293131904673e-12 121.764990699525 19.1554465183158 6.35667722927245 4.48783001579913e-10 -369.18928553978 112.979971114837 -3.26774101548071 0.0011551605023132 ABALON other 2.06200940308775e-08 1 5.06406738982773e-06 6.35667722927245 -3.26774101548071 0.190790119703568 8.37668586517222 5.54611178297803 1.51037090360885 0.131529419214719 27.2608532406161 18.7234674169278 1.45597247740393 0.145977090350697 PANDAR other 1 1 1 1.51037090360885 1.45597247740393 0.0234537666295526 27.888327385878 14.8759673460581 1.87472362214266 0.0613784187664924 -165.530690831072 92.1704623543083 -1.79591906781115 0.0730746906445641 TGFB2-OT1 other 1 1 1 1.87472362214266 -1.79591906781115 7.05048025903822e-14 203.274555735221 58.8788978877743 3.45241781058252 0.000599553350465764 -820.480850425459 144.528728374477 -5.67693952374352 2.25080741949333e-08 EBLN3P other 6.97856536039603e-10 0.000304151606596134 1 3.45241781058252 -5.67693952374352 9.31023403420808e-21 -0.347593161108971 5.4071712618269 -0.0642837343738084 0.948768680653073 -87.8328843740904 9.91701346861004 -8.85678784768263 1.25918269066701e-17 RBM5-AS1 other 1.11992805197489e-16 1.92201645903413e-13 1 -0.0642837343738084 -8.85678784768263 0.479276799735584 -13.5414063694648 15.9161699728574 -0.850795536398367 0.395256578681132 26.0626308507808 49.3325916278902 0.528304514130701 0.5975030495397 GIMAP1-GIMAP5 other 1 1 1 -0.850795536398367 0.528304514130701 0.00350702560003941 1.5774065595885 2.3210514508937 0.679608614010317 0.497070633643011 -20.4020300174761 6.92765847692565 -2.94501094207088 0.0033817225052961 LINC02246 other 1 1 1 0.679608614010317 -2.94501094207088 1.03586597601399e-19 167.915067385739 18.5635499186292 9.04541793578127 2.87124510183529e-18 -144.638344058179 112.880624904632 -1.28133897363147 0.200639209224135 TMEM265 other 1.21983577335408e-15 1 3.87216114433508e-14 9.04541793578127 -1.28133897363147 5.65115844631688e-05 4.20579318600428 1.41574811803789 2.97072136803062 0.00310323384766872 -33.0637872489073 11.1468338360531 -2.96620437114317 0.00314842662110101 PEG13 other 0.31725603517623 1 1 2.97072136803062 -2.96620437114317 0.0182832983651146 -2.89604401436652 9.33589995841867 -0.310205125083309 0.756523341348948 -56.6514968252363 21.0335681303807 -2.6933849965004 0.00729050153482126 ADORA3 other 1 1 1 -0.310205125083309 -2.6933849965004 5.71453686429234e-05 22.9543852353513 8.1686261408268 2.81006681412744 0.00513178344265955 -73.5476742113704 28.4430384579321 -2.58578823497176 0.00997498092516303 BISPR other 0.320642663455443 1 1 2.81006681412744 -2.58578823497176 0.159468686025531 -3.42488989958487 1.78567313500309 -1.91798254252111 0.0556533156128995 -3.04898016868454 19.5194236309959 -0.156202366746265 0.87593332802317 PRNCR1 other 1 1 1 -1.91798254252111 -0.156202366746265 5.56061724056712e-15 31.2620749833136 11.9422543648748 2.61776998112378 0.00910031303855073 -237.008539306819 34.4393657686172 -6.88190778248282 1.65172520734655e-11 PCBP2-OT1 other 5.73577668364498e-11 2.39037672007193e-07 1 2.61776998112378 -6.88190778248282 1.33719645560466e-14 5.26542840440941 5.41023070334563 0.973235466863423 0.330871230292594 -81.8279187389426 11.5253678167476 -7.09980974490355 3.94596333900255e-12 GTF2IP12 other 1.35926019712213e-10 5.75794970427252e-08 1 0.973235466863423 -7.09980974490355 0.000751854080456381 31.9769895654077 9.82051113115173 3.2561431007367 0.00120074674040042 79.6374803284815 37.6429987357022 2.11559873026136 0.0348395537989968 IQCJ-SCHIP1 other 1 1 1 3.2561431007367 2.11559873026136 3.56327208230272e-25 4.13851729896235 0.671211393290841 6.16574352034144 1.41112786401124e-09 -10.6194841308068 1.66612099344616 -6.37377727822863 4.07619710179156e-10 ARL17A other 4.61408101937379e-21 5.75966650483148e-06 1.56084853038283e-05 6.16574352034144 -6.37377727822863 3.10562201957926e-10 13.0179657354825 2.15875281544652 6.03031789574754 3.02997773632349e-09 -11.7259378600625 6.92544680222334 -1.69316698184701 0.090998301490575 TXNRD3NB other 2.6152443026877e-06 1 3.30752369697072e-05 6.03031789574754 -1.69316698184701 0.013639238013269 6.25319711625544 2.27355776878588 2.75040168413876 0.00615003065579311 13.4815583286402 7.54571223789283 1.78665153183803 0.0745495437601454 MIR1244-3 other 1 1 1 2.75040168413876 1.78665153183803 0.076971346401314 6.49971107676498 2.86408226730585 2.26938700433317 0.0236383542025152 6.99248378091524 9.17522129762993 0.762105191154516 0.446329958220576 MIR1244-4 other 1 1 1 2.26938700433317 0.762105191154516 4.04130222915115e-08 -56.5558712562794 39.9754348668658 -1.41476562905777 0.157710402764913 433.643825309538 90.21466047902 4.80679994811247 1.98810164215884e-06 MIR1244-2 other 0.000300915363982595 0.0248989849663973 1 -1.41476562905777 4.80679994811247 0.639800782918774 -5.40402627514103 6.34030436014106 -0.852329157747374 0.394406503297953 -9.10393668254644 11.8258886298732 -0.769831085636064 0.441734247130468 LINC02009 other 1 1 1 -0.852329157747374 -0.769831085636064 0.227290834098692 -28.8581793613957 16.7477207371337 -1.72311085277474 0.0854346548913231 -21.4912058178808 43.4816607463173 -0.494259084151956 0.62132200725523 WDFY4 other 1 1 1 -1.72311085277474 -0.494259084151956