GO id	GO term	Pathway	Enrichment score (ES)	Normalized enrichment score (NES)	P value	FDR	Size	Leading edge
GO:0006091	generation of precursor metabolites and energy	GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY	0.402077738950337	2.03411097836503	1.60784628989469e-05	0.0039720891702157	268	COX15,NDUFA10,IDH3B,GNAS,FASTKD1,PPARD,WDR93,AKT2,DLAT,NDUFS2,UQCRHL,OGDHL,PYGB,SCO1,ATPIF1,NDUFAB1,NDUFA7,PYGM,COX6A1,NDUFB4,TAZ,PGM5,CALM3,NNT,UQCRFS1,DLD,NDUFB11,NDUFV1,NDUFV2,PGAM2,PGAM1,OXA1L,PHKG1,NDUFC1,UQCRC1,SDHD,NDUFB9,GYS1,OGDH,GIPR,PINK1,ATP5D,DHTKD1,NDUFB7,NDUFS6,CS,SLC25A3,IDH3A,GSK3B,PDHA1,FASTKD2,SLC25A4,ACO2,UCN,COX10,PFKM,GCK,COQ9,SDHC,SUCLG2,NDUFB10,MDH2,NFATC4,ATP5B,STK40,MDH1,PPP1R3A,CALM1,PPP1R3B,COX4I1,PFKFB4,FH,IDH2,NDUFS1,ETFA,PFKP,PHKA2,MTOR,PHKB,CYC1,ALDOC,PDHB,MDH1B,ALDOA,HK3,COX6A2,ENO2,GALK1,IDH1,COX7B,TBRG4,GYG1,NDUFA11,PPP1CB,NDUFB3,NDUFS8,THTPA,COX7A1,FXN,PPP1R3E,NDUFA8,COX5A,ACADVL,AQP7,NDUFA4,EPM2A,PRKAG3,NDUFA9,NDUFA13,UQCRQ,DLST
GO:0003012	muscle system process	GO_MUSCLE_SYSTEM_PROCESS	0.366276288268141	1.84957993219704	1.61222713055815e-05	0.0039720891702157	264	P2RY1,DYSF,AGT,PDE5A,SGCA,SCN7A,MYOM1,ANK2,MYL12A,CFLAR,ANKRD2,HDAC2,CKMT2,NPY1R,TAZ,TIAM1,ADRB2,DMPK,SCN5A,ROCK2,CALM3,CACNA2D1,SMTN,MYOM2,RYR2,NEDD4L,MYBPC3,PGAM2,ATP1A2,DRD2,HRC,KCNJ2,MYL1,LMOD1,LMOD3,VEGFB,GJA1,NDUFS6,GUCY1A3,HDAC4,CACNG1,CAV3,KLF15,TCAP,DMD,PKP2,FXYD1,PLN,SLC8A1,AGTR2,TTN,KCNH2,TNNI3,MYH7,TPM2,CALM1,PXN,MYL9,MYLK,TMOD1,CACNA1C,MYL2,GJA5,MTOR,KCNA5,IKBKB,TBX20,NKX2-5,EMD,KCNMA1,MYL7,MYH13,SLC6A8,SRSF1,HOMER1,CYBA,ALDOA,SOD1,TNNT2,KCNIP2,HEY2,TNNC2,ADORA2B,MKKS,DES,ACTG2,GJC1,GNAO1,FGF12,TRDN,ATP1A3,PSMB9,ATP2A2,TNNT3,PRKG1
GO:0015980	energy derivation by oxidation of organic compounds	GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS	0.452611196491816	2.20514444053459	1.65073705409465e-05	0.0039720891702157	197	COX15,NDUFA10,IDH3B,GNAS,FASTKD1,AKT2,DLAT,NDUFS2,UQCRHL,OGDHL,PYGB,NDUFAB1,NDUFA7,PYGM,COX6A1,NDUFB4,TAZ,PGM5,CALM3,NNT,UQCRFS1,DLD,NDUFB11,NDUFV1,NDUFV2,OXA1L,PHKG1,NDUFC1,UQCRC1,SDHD,NDUFB9,GYS1,OGDH,PINK1,DHTKD1,NDUFB7,NDUFS6,CS,IDH3A,GSK3B,PDHA1,FASTKD2,ACO2,UCN,COX10,PFKM,GCK,COQ9,SDHC,SUCLG2,NDUFB10,MDH2,NFATC4,STK40,MDH1,PPP1R3A,CALM1,PPP1R3B,COX4I1,FH,IDH2,NDUFS1,ETFA,PHKA2,MTOR,PHKB,CYC1,PDHB,MDH1B,IDH1,COX7B,TBRG4,GYG1,NDUFA11,PPP1CB,NDUFB3,NDUFS8,FXN,PPP1R3E,NDUFA8,COX5A,ACADVL,NDUFA4,EPM2A,PRKAG3,NDUFA9,NDUFA13,UQCRQ,DLST
GO:0045333	cellular respiration	GO_CELLULAR_RESPIRATION	0.52215496976188	2.40011949461202	1.69365219158594e-05	0.0039720891702157	129	COX15,NDUFA10,IDH3B,FASTKD1,DLAT,NDUFS2,UQCRHL,OGDHL,NDUFAB1,NDUFA7,COX6A1,NDUFB4,TAZ,NNT,UQCRFS1,DLD,NDUFB11,NDUFV1,NDUFV2,OXA1L,NDUFC1,UQCRC1,SDHD,NDUFB9,OGDH,PINK1,DHTKD1,NDUFB7,NDUFS6,CS,IDH3A,PDHA1,FASTKD2,ACO2,UCN,COX10,COQ9,SDHC,SUCLG2,NDUFB10,MDH2,NFATC4,MDH1,COX4I1,FH,IDH2,NDUFS1,ETFA,CYC1,PDHB,MDH1B,IDH1,COX7B,TBRG4,NDUFA11,NDUFB3,NDUFS8,FXN,NDUFA8,COX5A,NDUFA4,NDUFA9,NDUFA13,UQCRQ,DLST
GO:0022900	electron transport chain	GO_ELECTRON_TRANSPORT_CHAIN	0.505290473236642	2.17032560216274	1.74425703371649e-05	0.0039720891702157	86	COX15,NDUFA10,WDR93,NDUFS2,UQCRHL,NDUFAB1,NDUFA7,COX6A1,NDUFB4,TAZ,UQCRFS1,DLD,NDUFB11,NDUFV1,NDUFV2,NDUFC1,UQCRC1,NDUFB9,PINK1,NDUFB7,NDUFS6,COX10,COQ9,SDHC,NDUFB10,COX4I1,NDUFS1,ETFA,CYC1,COX7B,NDUFA11,NDUFB3,NDUFS8,NDUFA8,COX5A,NDUFA4,NDUFA9,NDUFA13,UQCRQ,SLC25A12
GO:0003015	heart process	GO_HEART_PROCESS	0.510537354945792	2.16576990397568	1.75183504721195e-05	0.0039720891702157	80	ANK2,SGCD,TAZ,SCN5A,CACNA2D1,SGCG,RYR2,NEDD4L,MYBPC3,ATP1A2,KCNJ2,MYL1,VEGFB,GJA1,CAV3,TCAP,DMD,PKP2,PLN,SLC8A1,AKAP13,TTN,KCNH2,TNNI3,MYH7,RAMP3,CACNA1C,MYL2,GJA5,MTOR,KCNA5,NKX2-5,SRSF1,SOD1,TNNT2,GJC1,FGF12,TRDN,ATP1A3
GO:0006119	oxidative phosphorylation	GO_OXIDATIVE_PHOSPHORYLATION	0.560610102033589	2.35099598611204	1.75771637488575e-05	0.0039720891702157	75	COX15,NDUFA10,NDUFS2,UQCRHL,NDUFAB1,NDUFA7,COX6A1,NDUFB4,TAZ,UQCRFS1,DLD,NDUFB11,NDUFV1,NDUFV2,NDUFC1,UQCRC1,NDUFB9,ATP5D,NDUFB7,NDUFS6,COX10,COQ9,SDHC,NDUFB10,COX4I1,NDUFS1,CYC1,COX7B,NDUFA11,NDUFB3,NDUFS8,FXN,NDUFA8,COX5A,NDUFA4,NDUFA9,NDUFA13,UQCRQ
GO:0006942	regulation of striated muscle contraction	GO_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION	0.510021020844545	2.13375443110054	1.75898401083534e-05	0.0039720891702157	74	PRKACA,PDE5A,TRPM4,ANK2,CTNNA3,DMPK,SCN5A,CALM3,RYR2,MYBPC3,ATP1A2,HRC,RNF207,KCNJ2,BMP10,HDAC4,CAV3,DMD,UCN,PKP2,PLN,SLC8A1,MYH7,CALM1,CACNA1C,MYL2,GJA5,NKX2-5,ACE2,MYBPH,SMAD7,SUMO1,ATP2A2,TNNT3
GO:0055117	regulation of cardiac muscle contraction	GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION	0.519082360785328	2.1058629408946	1.77028749468914e-05	0.0039720891702157	63	PRKACA,PDE5A,TRPM4,ANK2,CTNNA3,SCN5A,CALM3,RYR2,ATP1A2,HRC,RNF207,KCNJ2,BMP10,HDAC4,CAV3,DMD,UCN,PKP2,PLN,SLC8A1,CALM1,CACNA1C,GJA5,NKX2-5,ACE2
GO:0033108	mitochondrial respiratory chain complex assembly	GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY	0.567942074108347	2.25686400673036	1.78367579908676e-05	0.0039720891702157	57	NDUFA10,NDUFS2,ACAD9,NDUFAB1,NDUFA7,NDUFB4,TAZ,NDUFB11,NDUFV1,NDUFV2,OXA1L,FOXRED1,NDUFC1,NDUFB9,NDUFB7,NDUFS6,NDUFAF4,NDUFB10,TIMMDC1,BCS1L,IMMP1L,NDUFS1,NDUFA11,NDUFB3,NDUFS8,NDUFA8,NDUFA9,NDUFA13
GO:0097031	mitochondrial respiratory chain complex i biogenesis	GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_BIOGENESIS	0.627492233363603	2.38424774016776	1.79726815240834e-05	0.0039720891702157	46	NDUFA10,NDUFS2,ACAD9,NDUFAB1,NDUFA7,NDUFB4,TAZ,NDUFB11,NDUFV1,NDUFV2,OXA1L,FOXRED1,NDUFC1,NDUFB9,NDUFB7,NDUFS6,NDUFAF4,NDUFB10,TIMMDC1,BCS1L,NDUFS1,NDUFA11,NDUFB3,NDUFS8,NDUFA8,NDUFA9,NDUFA13,ECSIT
GO:0009060	aerobic respiration	GO_AEROBIC_RESPIRATION	0.605890261932881	2.32348386601132	1.79823772702751e-05	0.0039720891702157	48	IDH3B,DLAT,OGDHL,NNT,DLD,NDUFV1,OXA1L,UQCRC1,SDHD,OGDH,DHTKD1,CS,IDH3A,PDHA1,ACO2,UCN,COX10,SDHC,SUCLG2,MDH2,MDH1,FH,IDH2,PDHB,MDH1B,IDH1,FXN,DLST,SDHB,UQCRC2,SDHA,MTFR1,IDH3G,CHCHD5
GO:0002455	humoral immune response mediated by circulating immunoglobulin	GO_HUMORAL_IMMUNE_RESPONSE_MEDIATED_BY_CIRCULATING_IMMUNOGLOBULIN	-0.565262387365258	-2.22276358505433	2.25418150669492e-05	0.0039720891702157	46	C3,CD55,C4A,C2,CFI,C9,C4BPA,MASP2,HLA-DRB5,C1RL,SERPING1,C1R,C1S,C4BPB,IGHG4,IGHG2,IGHG1,MBL2,C5,IGHD,IGKC,IGLL1,IGLC1,HLA-DRB1
GO:0006956	complement activation	GO_COMPLEMENT_ACTIVATION	-0.563394363080006	-2.2745174124922	2.26515958049245e-05	0.0039720891702157	52	CFB,C3,CD55,C4A,C2,CFI,CFH,C9,C4BPA,MASP2,C1RL,SERPING1,C1R,C1S,C4BPB,FCN3,IGHG4,MASP1,IGHG2,IGHG1,MBL2,C5,IGHD,IGKC,COLEC10,IGLL1,IGLC1
GO:0019724	b cell mediated immunity	GO_B_CELL_MEDIATED_IMMUNITY	-0.463380021256405	-2.01972875389433	2.32455426671936e-05	0.0039720891702157	76	GCNT3,C3,CD55,C4A,C2,CFI,C9,C4BPA,MASP2,HLA-DRB5,C1RL,SERPING1,C1R,C1S,C4BPB,EXOSC6,IRF7,IGHG4,IGHG2,IGHG1,MBL2,FAS,C5,IGHD,IGKC,RNF8,POU2F2,IGLL1,IGLC1,HLA-DRB1,NBN,SWAP70,IL4R,CD46
GO:0072599	establishment of protein localization to endoplasmic reticulum	GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM	-0.509238197135899	-2.28833712058127	2.35721188977677e-05	0.0039720891702157	90	RPL24,SRP72,RPL38,RPL35,SEC63,RPL30,RPL9,RPL3,RPS3A,RPS19,SEC61G,RPS27,RPL4,RPS11,RPL7A,RPS4Y1,RPS8,RPL18,RAB3GAP2,RPS24,RPL18A,UBA52,RAB10,RPL15,RPS16,RPL5,RPL10A,RPS3,RPL22,SRP54,SPCS1,RPS29,RPL26,RPL19,SRP14,RPS28,RPS5,RPS17,SEC61A1,RPL36,RPS6,RPL23A,RPS18,FAU,RPL32,RPLP0,RPL14,RPS15,RPS13,RPL28,RPS4X,RPL34,RPL27,SRP68,RPL13
GO:0030216	keratinocyte differentiation	GO_KERATINOCYTE_DIFFERENTIATION	-0.437005808372722	-1.98968785929636	2.37135404315864e-05	0.0039720891702157	97	TGM1,DNASE1L2,LCE3C,EVPL,SFN,SPRR2F,PIP5K1A,CYP26B1,SPRR2E,WNT5A,HRNR,PPL,LCE5A,LCE2B,CDSN,SCEL,ANXA1,FLG,SPRR3,TCHH,LCE1C,AKR1C3,TMEM79,ST14,CASP3,CDH3,SPRR1A,LCE3A,PRR9,CRCT1,KRT16,EPHA2,FOSL2,ADAM9
GO:0070972	protein localization to endoplasmic reticulum	GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM	-0.445325385619373	-2.06778936656074	2.40257556100139e-05	0.0039720891702157	109	RPL24,SRP72,RPL38,KDELR3,RPL35,SEC63,RPL30,RPL9,RPL3,RPS3A,RPS19,SEC61G,RPS27,RPL4,RPS11,RPL7A,RPS4Y1,RPS8,BCAP31,RPL18,KDELR2,RAB3GAP2,RPS24,RPL18A,UBA52,RAB10,RPL15,RPS16,RPL5,RPL10A,RPS3,RPL22,SRP54,SPCS1,RPS29,RPL26,RPL19,SRP14,RPS28,RPS5,RPS17,SEC61A1,RPL36,RPS6,RPL23A,RPS18,FAU,RPL32,RPLP0,RPL14,RPS15,RPS13,RPL28,RPS4X,RPL34,RPL27,SRP68,RPL13
GO:0006413	translational initiation	GO_TRANSLATIONAL_INITIATION	-0.40512853770189	-1.92759337515194	2.44343449152128e-05	0.0039720891702157	127	RPL24,RPL38,EIF4E1B,RPL35,RPL30,RPL9,RPL3,RPS3A,RPS19,RPS27,RPL4,RPS11,RPL7A,EIF3H,RPS4Y1,EIF4A2,RPS8,PABPC1,EIF3L,RPL18,DDX3Y,RPS24,RPL18A,UBA52,RPL15,EIF2D,RPS16,CDC123,RPL5,RPL10A,RPS3,RPL22,RPS29,RPL26,RPL19,DENR,EIF4H,RPS28,RPS5,RPS17,RPL36,EIF1AY,RPS6,EIF1AX,EIF4EBP1,MTFMT,RPL23A,EIF3G,RPS18,FAU,RPL32,PTBP1,RPLP0,RPL14,RPS15,RPS13,RPL28,RPS4X,RPL34,EIF2S3,RPL27
GO:0006612	protein targeting to membrane	GO_PROTEIN_TARGETING_TO_MEMBRANE	-0.418416114398854	-2.02526613396841	2.45597661910259e-05	0.0039720891702157	141	RPL24,SRP72,RPL38,PIP5K1A,RPL35,SEC63,PRKG2,RPL30,RPL9,PRKCI,RPL3,RPS3A,TMED2,RPS19,RPS27,RPL4,ANXA2,TRAM1,RPS11,RPL7A,SSR1,RPS4Y1,RPS8,RPL18,SSR2,RPS24,RPL18A,UBA52,RPL15,RPS16,RPL5,RPL10A,RPS3,RPL22,SRP54,RPS29,RPL26,RPL19,KCNB1,INPP5K,SRP14,RPS28,RPS5,RPS17,CHM,SEC61A1,TESC,RPL36,PEX5,RPS6,RPL23A,RPS18,FAU,RPL32,RPLP0,RPL14,RPS15,PALM,EHD3,PARD3,RPS13,RPL28,RPS4X,RPL34,GAS6,RPL27,SRP68,RPL13
GO:0006959	humoral immune response	GO_HUMORAL_IMMUNE_RESPONSE	-0.361619386404902	-1.77118205913227	2.47813049835204e-05	0.0039720891702157	153	CFB,SLPI,C3,DEFA5,CD55,C4A,C2,CFI,CFH,C9,TRAF3IP2,C4BPA,TNFRSF21,CCR6,GATA3,MASP2,HLA-DRB5,C1RL,SERPING1,C1R,DEFA6,C1S,HIST1H2BE,C4BPB,HIST1H2BK,BST1,IFNA14,KLK3,SEMG2,FCN3,TFE3,IGHG4,MASP1,IGHG2,IGHG1,IFNE,MBL2,C5,IGHD,IFNA16,IGKC,COLEC10,POU2F2,IGLL1,IGLC1,HLA-DRB1,HIST1H2BF
GO:0008544	epidermis development	GO_EPIDERMIS_DEVELOPMENT	-0.323913143400696	-1.69318974123657	2.60010400416017e-05	0.00397815912636505	244	TGM1,DNASE1L2,EDA2R,LCE3C,EVPL,SFN,KRT71,SPRR2F,PIP5K1A,BNC1,CYP26B1,PDZD7,SPRR2E,WNT5A,LAMA3,KRT31,HRNR,LAMC2,KLK7,CTGF,PPL,LCE5A,FGF7,LCE2B,LRTOMT,GRHL2,FGFR2,CDSN,SCEL,ALDH3A2,GRXCR1,ANXA1,FLG,SPRR3,POU3F2,KLF4,TCHH,ATP2B2,KRT25,EDAR,CTNNB1,LCE1C,AKR1C3,EGFR,TMEM79,ST14,CASP3,CDH3,FZD3,PTHLH,SPRR1A,LCE3A,EMP1,COL7A1,PRR9,KRT14,KLK5,KRT76,KRT15,CRCT1,KRT16,EPHA2,FOSL2,ADAM9
GO:1903034	regulation of response to wounding	GO_REGULATION_OF_RESPONSE_TO_WOUNDING	-0.285303508897401	-1.56946940451434	2.80300482116829e-05	0.00410213662089238	386	VTN,SMPDL3B,PLA2G2A,CMA1,PTPRF,CFB,PRKCA,PTGIS,C3,CD55,C4A,TYRO3,C2,CNR1,CCL3,TNFSF11,MAPK13,CFI,IL17B,CFH,IL18,C9,FFAR3,WNT5A,C4BPA,PTPN2,OSMR,ANO6,GATA3,FAP,TBC1D23,MAP2K2,FOXF1,C1QTNF1,ANXA5,SERPING1,RPS19,ANXA1,ANXA2,AGTR1,KLF4,INSL3,C4BPB,F7,S100A12,NLRP6,CNR2,IL6ST,HPSE,SLC7A2,LPL,F2,IL20,PLAUR,SAA1,TNFRSF1A,ADAMTS18,ADIPOQ,FABP4,LEP,IL17RC,TLR10,MASP1,DUOXA1,HOPX,MMP26,CERS2,VAMP8,C5AR1,NOV,PPARG,SERPINB2,S100A9,GGT1,IL17F,NR1H3,EDNRB,PROS1,PGLYRP1,HGF,C5,MVK,IL1R1,NLRP3,NLRP12,TLR9,CD34,STX2,MYOD1,SOX15,ADCYAP1,THBS1,F2R,TXK,CREB3L3,CASK,BRD4,CCL4,ABAT,IL2RA,TLR2,EDN1,NFE2L2,SCARA5,FCER1A,CCL18,IL17RB,ELANE,PTGER4,F3,SOCS3,IL20RB,CD276,STAB2,PSMA6,CUEDC2,CD46,SERPINF1,SERPINC1,IL10,RICTOR,FGF2,PLA2G4A,THBD,ISL1,HRAS,PGLYRP2,ZAP70,STK24,KLK8,TLR3,SEMA7A,DUOXA2,SPP1
GO:0090257	regulation of muscle system process	GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS	0.369959453017779	1.78711251157557	3.31301351709515e-05	0.00464650145772595	184	AGT,PRKACA,PDE5A,TRPM4,ANK2,CTNNA3,FLT1,ADRB2,DMPK,SCN5A,CALM3,PPP1R12B,AKAP1,PIN1,ANXA6,RYR2,MYBPC3,ATP1A2,HRC,RNF207,KCNJ2,BMP10,GHSR,ADRA2C,GTF2IRD1,TACR3,GUCY1A3,HDAC4,PLCE1,MTMR4,GSK3B,AKAP6,CAV3,DMD,UCN,PKP2,PLN,DOCK4,DDX39B,SLC8A1,AKAP13,TNNI3,MYH7,CALM1,SRL,CAMK2G,MYL9,EP300,ADA,CACNA1C,MYL2,GJA5,MTOR,DAPK3,NKX2-5,ACE2,CAMK2B,SOD1,MYBPH,TNNT2,CHRM2,TNNC2,NMUR2,ADORA2B,PTAFR,SMAD7,SUMO1,ATP2A2,TNNT3,PRKG1
GO:2000257	regulation of protein activation cascade	GO_REGULATION_OF_PROTEIN_ACTIVATION_CASCADE	-0.594482747320818	-2.16340927128274	4.43242764061877e-05	0.00537182235003663	33	VTN,CFB,C3,CD55,C4A,C2,CFI,CFH,C9,C4BPA,SERPING1,C4BPB,MASP1,C5AR1,PROS1,C5
GO:0031424	keratinization	GO_KERATINIZATION	-0.516781010107915	-2.05147488573115	4.50531627320238e-05	0.00537182235003663	48	TGM1,LCE3C,EVPL,SFN,SPRR2F,CYP26B1,SPRR2E,HRNR,PPL,LCE5A,LCE2B,SPRR3,TCHH,LCE1C,TMEM79,CDH3,SPRR1A,LCE3A
GO:0002920	regulation of humoral immune response	GO_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE	-0.523680178268676	-2.06889890131636	4.50673757267114e-05	0.00537182235003663	47	VTN,CFB,C3,CD55,C4A,C2,CFI,CFH,C9,C4BPA,KLK7,SERPING1,C4BPB,MASP1,C5AR1,KLK5,PROS1,C5
GO:0072376	protein activation cascade	GO_PROTEIN_ACTIVATION_CASCADE	-0.448484273263579	-1.94556611645091	4.63488679289008e-05	0.00537182235003663	74	CFB,C3,CD55,C4A,C2,CFI,CFH,C9,C4BPA,MASP2,C1RL,SERPING1,C1R,C1S,C4BPB,F7,F2,FCN3,IGHG4,MASP1,IGHG2,IGHG1,MBL2,C5,IGHD,IGKC,COLEC10,IGLL1,IGLC1
GO:0072521	purine containing compound metabolic process	GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	0.304311424987686	1.58725752470272	4.70219435736677e-05	0.00537182235003663	356	COX15,SLC17A3,ATP5L,NDUFA10,PANK3,SULT1A2,BAD,CECR1,PDE5A,GUCY1A2,NDUFS2,UQCRHL,DLG4,OGDHL,NDUFAB1,NDUFA7,PDE8B,MCCC2,COX6A1,GMPR,NDUFB4,TAZ,AK1,LRRK2,PPAT,UQCRFS1,DLD,NDUFB11,NDUFV1,NDUFV2,GUCY1B3,PGAM2,ATP1A2,PGAM1,NDUFC1,UQCRC1,ATP5A1,MTHFR,NDUFB9,ATP5G2,MACROD1,OGDH,DLG2,ATP5D,DHTKD1,NDUFB7,OAS2,NDUFS6,HMGCR,GUCY1A3,COASY,PDE4C,AK4,SULT1C4,ADCY7,NPR2,COX10,PFKM,ATP5O,ADCY5,GCK,COQ9,SDHC,NDUFB10,ATP5B,MYH7,PDE2A,NFS1,SLC17A1,COX4I1,PFKFB4,NME6,ADA,ATP5G3,GUCY2C,NDUFS1,ADCY8,ADCY9,OAS1,PFKP,ADSSL1,CYC1,ALDOC,PANK4,ADCY4,MOCS2,VCP,ALDOA,HK3,PDE7A,ENO2,GALK1,COX7B,NDUFA11,GPHN,NDUFB3,NME5,NDUFS8,ACACB,FXN,NDUFA8,ABCG2,COX5A,PTH,NDUFA4
GO:0006936	muscle contraction	GO_MUSCLE_CONTRACTION	0.362761600184147	1.78961154091772	4.90893917824358e-05	0.00537182235003663	217	DYSF,AGT,SGCA,SCN7A,MYOM1,ANK2,MYL12A,ANKRD2,CKMT2,NPY1R,TAZ,ADRB2,DMPK,SCN5A,ROCK2,CALM3,CACNA2D1,SMTN,MYOM2,RYR2,NEDD4L,MYBPC3,PGAM2,ATP1A2,DRD2,HRC,KCNJ2,MYL1,LMOD1,LMOD3,VEGFB,GJA1,NDUFS6,CACNG1,CAV3,TCAP,DMD,PKP2,FXYD1,SLC8A1,TTN,KCNH2,TNNI3,MYH7,TPM2,CALM1,PXN,MYL9,MYLK,TMOD1,CACNA1C,MYL2,GJA5,MTOR,KCNA5,IKBKB,TBX20,NKX2-5,EMD,KCNMA1,MYL7,MYH13,SLC6A8,SRSF1,HOMER1,ALDOA,TNNT2,KCNIP2,TNNC2,MKKS,DES,ACTG2,GJC1,GNAO1,FGF12,TRDN,ATP1A3
GO:0009141	nucleoside triphosphate metabolic process	GO_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS	0.366627477213422	1.7907822280063	4.94731113639737e-05	0.00537182235003663	201	COX15,ATP5L,NDUFA10,BAD,CMPK2,NDUFS2,UQCRHL,OGDHL,NDUFAB1,NDUFA7,COX6A1,NDUFB4,TAZ,AK1,LRRK2,UQCRFS1,DLD,UCKL1,NDUFB11,NDUFV1,NDUFV2,PGAM2,ATP1A2,PGAM1,NDUFC1,UQCRC1,ATP5A1,NDUFB9,ATP5G2,OGDH,ATP5D,DHTKD1,NDUFB7,NDUFS6,AK4,COX10,PFKM,ATP5O,GCK,COQ9,SDHC,NDUFB10,ATP5B,MYH7,NFS1,COX4I1,PFKFB4,NME6,ADA,ATP5G3,NDUFS1,PFKP,CYC1,ALDOC,MOCS2,VCP,ALDOA,HK3,ENO2,GALK1,COX7B,NDUFA11,GPHN,NDUFB3,NME5,NDUFS8,FXN,NDUFA8,COX5A,NDUFA4,CAD,ENPP3,NDUFA9,NUDT15,NDUFA13,UQCRQ
GO:0072350	tricarboxylic acid metabolic process	GO_TRICARBOXYLIC_ACID_METABOLIC_PROCESS	0.582999596487483	2.11166008415246	5.43114216919818e-05	0.00571288266922534	37	IDH3B,DLAT,STAT5B,OGDHL,NNT,DLD,SDHD,OGDH,DHTKD1,CS,IDH3A,PDHA1,ACO2,SIRT4,SDHC,SUCLG2,MDH2,MDH1,FH,IDH2,GLUD1,PDHB,MDH1B,IDH1
GO:0006941	striated muscle contraction	GO_STRIATED_MUSCLE_CONTRACTION	0.446236767625139	1.93275963167048	6.94697719654735e-05	0.0070636377944494	90	ANK2,TAZ,ADRB2,DMPK,SCN5A,CACNA2D1,RYR2,NEDD4L,MYBPC3,PGAM2,ATP1A2,KCNJ2,MYL1,VEGFB,GJA1,CAV3,TCAP,DMD,PKP2,SLC8A1,TTN,KCNH2,TNNI3,MYH7,CACNA1C,MYL2,GJA5,MTOR,KCNA5,IKBKB,NKX2-5,SRSF1,HOMER1,ALDOA,TNNT2,TNNC2,GJC1,FGF12,ATP1A3,TNNT3,SNTA1,MYH8,MYL4
GO:1903115	regulation of actin filament based movement	GO_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT	0.593971680130134	2.07946554478071	7.28451494236127e-05	0.0070636377944494	32	TRPM4,ANK2,CTNNA3,SCN5A,RYR2,MYBPC3,ATP1A2,RNF207,KCNJ2,PKP2,PLN,CACNA1C,GJA5,TNNT2,SUMO1,ATP2A2,JUP,DSP
GO:0009913	epidermal cell differentiation	GO_EPIDERMAL_CELL_DIFFERENTIATION	-0.378144320506427	-1.82245048082375	7.34484024972457e-05	0.0070636377944494	137	TGM1,DNASE1L2,LCE3C,EVPL,SFN,SPRR2F,PIP5K1A,CYP26B1,PDZD7,SPRR2E,WNT5A,HRNR,PPL,LCE5A,LCE2B,LRTOMT,CDSN,SCEL,GRXCR1,ANXA1,FLG,SPRR3,KLF4,TCHH,ATP2B2,CTNNB1,LCE1C,AKR1C3,TMEM79,ST14,CASP3,CDH3,SPRR1A,LCE3A,PRR9,CRCT1,KRT16,EPHA2,FOSL2,ADAM9
GO:0006937	regulation of muscle contraction	GO_REGULATION_OF_MUSCLE_CONTRACTION	0.395455576330507	1.83672159276361	8.44794377048626e-05	0.00789882742540466	139	PRKACA,PDE5A,TRPM4,ANK2,CTNNA3,FLT1,ADRB2,DMPK,SCN5A,CALM3,PPP1R12B,ANXA6,RYR2,MYBPC3,ATP1A2,HRC,RNF207,KCNJ2,BMP10,GHSR,ADRA2C,TACR3,GUCY1A3,HDAC4,PLCE1,CAV3,DMD,UCN,PKP2,PLN,DOCK4,SLC8A1,TNNI3,MYH7,CALM1,MYL9,ADA,CACNA1C,MYL2,GJA5,DAPK3,NKX2-5,ACE2,SOD1,MYBPH,TNNT2,CHRM2,TNNC2,NMUR2,ADORA2B,PTAFR,SMAD7,SUMO1,ATP2A2,TNNT3,PRKG1
GO:0048738	cardiac muscle tissue development	GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.396455234159716	1.8223324326141	0.000101619131495156	0.00924459450304583	129	AGT,UBE4B,TBX2,SGCD,TAZ,NDRG4,SGCG,TSC1,RYR2,NDUFV2,MYBPC3,BMP10,SMAD1,XIRP2,CAV3,OBSL1,PTEN,NPRL3,TCAP,PKP2,PRKAR1A,PLN,SLC8A1,AKAP13,AGTR2,TTN,KAT2A,TNNI3,MYH7,EGLN1,DLL4,MYL2,GJA5,MTOR,TBX5,TBX20,S1PR1,NKX2-5,FHL2,RXRA,CDK1,VEGFA,FHOD3,TNNT2,MYLK3,HEY2,LRRC10,GJC1,SMAD7,MARCKS,PROX1,TBX3,MED1,NOX4,MEF2C,SRF,SGCB,DSP,PTCD2,TGFBR3,ACTN2,FOXC2,RARB,MYOCD
GO:0055006	cardiac cell development	GO_CARDIAC_CELL_DEVELOPMENT	0.520618501467649	1.98732445080571	0.000107867107723285	0.00955475485780466	47	AGT,BMP10,CAV3,OBSL1,TCAP,SLC8A1,AGTR2,TTN,MYL2,MTOR,NKX2-5,FHL2,CDK1,VEGFA,FHOD3,MYLK3,HEY2,LRRC10,PROX1,TBX3,SRF,SGCB,ACTN2,MYOCD,NEBL,CSRP3
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_REGULATION_OF_THE_RELEASE_OF_SEQUESTERED_CALCIUM_ION	0.689405895745317	2.07993181737108	0.000111406131050745	0.00961520607991819	18	PRKACA,ANK2,CALM3,RYR2,ATP1A2,HRC,DMD,PLN,SLC8A1,CALM1,CACNA1C
GO:0000184	nuclear transcribed mrna catabolic process nonsense mediated decay	GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY	-0.392004655803634	-1.80387155517529	0.000119056123056409	0.0100185727551968	103	RPL24,RPL38,SMG9,RPL35,RPL30,RPL9,RPL3,RPS3A,RPS19,RPS27,RPL4,RPS11,RPL7A,RPS4Y1,RPS8,PABPC1,RPL18,RPS24,RPL18A,UBA52,RPL15,RPS16,PARN,RPL5,RPL10A,RPS3,RPL22,RPS29,RPL26,RPL19,EXOSC10,RPS28,RPS5,RPS17,RPL36,RPS6,RPL23A,RPS18,FAU,RPL32,RPLP0,RPL14,RPS15,RPS13,RPL28,RPS4X,RPL34,UPF3B,RPL27,RPL13,UPF3A
GO:0050727	regulation of inflammatory response	GO_REGULATION_OF_INFLAMMATORY_RESPONSE	-0.301079000068379	-1.59472851327507	0.000132675264023775	0.010892315578147	274	VTN,SMPDL3B,PLA2G2A,CMA1,CFB,PTGIS,C3,CD55,C4A,TYRO3,C2,CNR1,CCL3,TNFSF11,MAPK13,CFI,IL17B,CFH,IL18,C9,FFAR3,WNT5A,C4BPA,PTPN2,OSMR,GATA3,TBC1D23,FOXF1,SERPING1,RPS19,ANXA1,AGTR1,KLF4,C4BPB,S100A12,NLRP6,CNR2,IL6ST,SLC7A2,LPL,IL20,SAA1,TNFRSF1A,ADIPOQ,FABP4,LEP,IL17RC,TLR10,MASP1,DUOXA1,MMP26,VAMP8,C5AR1,NOV,PPARG,S100A9,GGT1,IL17F,NR1H3,EDNRB,PROS1,PGLYRP1,HGF,C5,MVK,IL1R1,NLRP3,NLRP12,TLR9,ADCYAP1,CREB3L3,BRD4,CCL4,IL2RA,TLR2,FCER1A,CCL18,IL17RB,ELANE,PTGER4,SOCS3,IL20RB,CD276,PSMA6,CUEDC2,CD46,SERPINF1,SERPINC1,IL10,RICTOR,PLA2G4A
GO:0086004	regulation of cardiac muscle cell contraction	GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_CONTRACTION	0.598826031044647	2.00996690702498	0.000146512096404959	0.0116779238321353	27	TRPM4,ANK2,CTNNA3,SCN5A,RYR2,ATP1A2,RNF207,KCNJ2,PKP2,PLN,CACNA1C,GJA5,SUMO1,ATP2A2,JUP,DSP
GO:0002443	leukocyte mediated immunity	GO_LEUKOCYTE_MEDIATED_IMMUNITY	-0.343079266346531	-1.6923660514133	0.000149183221860315	0.0116779238321353	160	RAET1E,GCNT3,MRGPRX2,C3,CD55,C4A,C2,CCL3,CFI,ANXA3,C9,IRAK4,C4BPA,GATA3,MASP2,HLA-DRB5,C1RL,SERPING1,C1R,C1S,C4BPB,NR4A3,STXBP3,SNAP23,EXOSC6,IRF7,ULBP3,IGHG4,CEBPG,IGHG2,VAMP8,IGHG1,LAT,MBL2,RAET1G,FAS,C5,IGHD,IGKC,RNF8,POU2F2,IGLL1,IGLC1,HLA-DRB1,ELANE,DLG1,GNL1,CXCL5,ULBP2,NBN,SWAP70,IL4R,CD46
GO:0090150	establishment of protein localization to membrane	GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE	-0.306284984191614	-1.59806402249521	0.000155965687548739	0.0119313750974786	241	RPL24,SRP72,RPL38,BBC3,EZR,PIP5K1A,RPL35,SEC63,S100A10,RAB31,PRKG2,RPL30,AMN,KRT18,RPL9,PRKCI,RPL3,RPS3A,TMED2,RPS19,RPS27,TIMM10,RPL4,ANXA2,TRAM1,TIMM9,RPS11,SPTBN4,RPL7A,SSR1,RPS4Y1,RPS8,RPL18,EGFR,TSPAN15,SSR2,RAB3GAP2,REEP1,RPS24,RPL18A,UBA52,RAB13,RAB10,TNFRSF1A,RPL15,RPS16,MPP5,RPL5,GOLGA7,RPL10A,RPS3,TSPAN5,RPL22,SRP54,GCC2,RPS29,CDH1,RPL26,RPL19,KCNB1,INPP5K,SRP14,BAX,GRIN3B,RILPL2,RPS28,F11R,WRB,RPS5,HSP90AA1,RPS17,CHM,SEC61A1,TESC,GET4,RPL36,PEX5,RPS6,ATP1B1,ASNA1,RAB11A,RPL23A,RPS18,FAU,RPL32,RPLP0,RPL14,NSF,RPS15
GO:0000209	protein polyubiquitination	GO_PROTEIN_POLYUBIQUITINATION	0.332954400411693	1.65401084284081	0.000162694216220613	0.0121695273733019	229	C18orf25,UBE4B,FBXO6,LRSAM1,RC3H2,SIAH1,UBE2O,RNF144B,RBCK1,TRIP12,RNF187,CDC26,FBXW7,RNF213,PSMD11,RNF111,PSMD2,UBE2N,PSMC6,RNF31,SASH1,NEDD4L,PPIL2,RNF180,RNF14,UBE2T,HERC5,FZR1,BTRC,PELI1,ANAPC1,HUWE1,RUSC1,MARCH6,PSMC5,PSMB7,PSME4,UBR5,RNF167,TRIM36,RNF144A,FBXO31,MKRN1,MARCH5,RNF125,ANAPC11,UBE3C,RNF152,FBXO3,ARIH2,PSMA8,CBLB,HDAC6,PSMD8,TRIM32,RLIM,PSMB10,FBXL8,PRPF19,MARCH8
GO:0055086	nucleobase containing small molecule metabolic process	GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS	0.273339636488447	1.46523591652486	0.000183432947614607	0.0134225065580602	476	COX15,TK1,ATP5L,NDUFA10,IDH3B,ME1,PANK3,SULT1A2,BAD,CECR1,PDE5A,GSR,CMPK2,GUCY1A2,NDUFS2,UQCRHL,DLG4,OGDHL,UPP2,NDUFAB1,NDUFA7,PDE8B,MCCC2,COX6A1,GMPR,NDUFB4,TAZ,UNG,ENTPD4,NUDT13,AK1,LRRK2,NUDT4,PPAT,NNT,UQCRFS1,DLD,UCKL1,NDUFB11,NDUFV1,NDUFV2,TXNRD1,GUCY1B3,PGAM2,ATP1A2,PGAM1,NDUFC1,UQCRC1,ATP5A1,RPIA,MTHFR,NDUFB9,ATP5G2,MACROD1,OGDH,DLG2,HAAO,ATP5D,DHTKD1,NDUFB7,OAS2,NDUFS6,HMGCR,GUCY1A3,COASY,PDE4C,PDHA1,AK4,PRPSAP2,NMNAT3,SULT1C4,ADCY7,NPR2,COX10,PFKM,ATP5O,ADCY5,GCK,COQ9,SDHC,NDUFB10,MDH2,ATP5B,MYH7,PDE2A,MDH1,NFS1,COX4I1,PFKFB4,NME6,GLRX,ADA,TET2,ATP5G3,GUCY2C,NDUFS1,PDHX,ADCY8,ADCY9,OAS1,PFKP,MTOR,AICDA,ADSSL1,CYC1,ALDOC,PANK4,MAPK1,ADCY4,MOCS2,VCP,PDHB,ALDOA,HK3,PDE7A,ENO2,GALK1,IDH1,COX7B,NDUFA11,GPHN,NDUFB3,RFK,NME5,NDUFS8,APOBEC3H,ACACB,FXN,NDUFA8,COX5A,PTH,NDUFA4,CAD,ENPP3,DHODH,UPB1,NDUFA9,APOBEC1,NUDT15,NDUFA13,UQCRQ,DLST
GO:0042787	protein ubiquitination involved in ubiquitin dependent protein catabolic process	GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS	0.382584501690512	1.75343016253733	0.000220100230258702	0.0154940988013478	126	CUL4A,C18orf25,UHRF1,HERC2,UBE4B,SIAH1,RNF144B,TRIP12,CDC26,HECW2,KLHL21,RNF111,NEDD4L,MAD2L1,RNF14,UBE3B,HERC4,HERC5,FZR1,SIAH3,ANAPC1,HUWE1,UBR4,HECTD3,UBR5,RNF144A,KLHL7,WWP1,KLHL28,LNX1,ANAPC11,UBE3C,FBXO45,ARIH2,KLHL15,CDK1,TRIM32
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING	0.636350243362283	2.02691830827026	0.000220949715527241	0.0154940988013478	22	PRKACA,ANK2,CALM3,RYR2,ATP1A2,HRC,HDAC4,DMD,PLN,SLC8A1,CALM1,CACNA1C
GO:0098901	regulation of cardiac muscle cell action potential	GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.657437391143359	2.01183553969152	0.000240901341635164	0.0165484472641625	19	TRPM4,ANK2,CTNNA3,RYR2,RNF207,CAV3,PKP2,CACNA1C,GJA5,ANK3,ATP2A2,JUP,DSP
GO:1901657	glycosyl compound metabolic process	GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS	0.301627425960262	1.55958220066351	0.000253112492683467	0.017039533007451	327	COX15,TK1,ATP5L,NDUFA10,PANK3,SULT1A2,BAD,CECR1,NDUFS2,UQCRHL,DLG4,OGDHL,UPP2,NDUFAB1,NDUFA7,MCCC2,COX6A1,NDUFB4,TAZ,ENTPD4,AK1,LRRK2,PPAT,UQCRFS1,DLD,UCKL1,NDUFB11,NDUFV1,NDUFV2,PGAM2,ATP1A2,PGAM1,NDUFC1,UQCRC1,ATP5A1,MTHFR,NDUFB9,ATP5G2,MACROD1,OGDH,DLG2,ATP5D,DHTKD1,NDUFB7,NDUFS6,HMGCR,COASY,TYW5,AK4,SULT1C4,COX10,PFKM,ATP5O,GCK,COQ9,SDHC,NDUFB10,ATP5B,MYH7,NFS1,COX4I1,PFKFB4,NME6,ADA,ATP5G3,NDUFS1,PFKP,AICDA,ADSSL1,CYC1,ALDOC,PANK4,MOCS2,VCP,ALDOA,HK3,ENO2,GALK1,COX7B,NDUFA11,GPHN,NDUFB3,NME5,NDUFS8,APOBEC3H,ACACB,FXN,NDUFA8,COX5A,NDUFA4,NAGA,CAD,DHODH,UPB1,NDUFA9,FUCA2,APOBEC1,NDUFA13,UQCRQ
GO:0002673	regulation of acute inflammatory response	GO_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE	-0.430099304562294	-1.84009534168732	0.000277578589438135	0.0179966486266162	69	VTN,CFB,C3,CD55,C4A,C2,CNR1,TNFSF11,CFI,CFH,C9,FFAR3,C4BPA,OSMR,SERPING1,C4BPB,IL6ST,MASP1,C5AR1,PPARG,EDNRB,PROS1,C5,NLRP3,ADCYAP1,CREB3L3
GO:0009123	nucleoside monophosphate metabolic process	GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS	0.329697750817434	1.62819643528845	0.000278023092270958	0.0179966486266162	219	COX15,TK1,ATP5L,NDUFA10,BAD,NDUFS2,UQCRHL,DLG4,OGDHL,UPP2,NDUFAB1,NDUFA7,COX6A1,NDUFB4,TAZ,AK1,PPAT,UQCRFS1,DLD,UCKL1,NDUFB11,NDUFV1,NDUFV2,PGAM2,ATP1A2,PGAM1,NDUFC1,UQCRC1,ATP5A1,NDUFB9,ATP5G2,OGDH,DLG2,ATP5D,DHTKD1,NDUFB7,NDUFS6,AK4,COX10,PFKM,ATP5O,GCK,COQ9,SDHC,NDUFB10,ATP5B,MYH7,COX4I1,PFKFB4,ADA,ATP5G3,NDUFS1,PFKP,ADSSL1,CYC1,ALDOC,VCP,ALDOA,HK3,ENO2,GALK1,COX7B,NDUFA11,NDUFB3,RFK,NDUFS8,FXN,NDUFA8,COX5A,NDUFA4,CAD,DHODH,NDUFA9,NDUFA13,UQCRQ
GO:0030855	epithelial cell differentiation	GO_EPITHELIAL_CELL_DIFFERENTIATION	-0.255909548408063	-1.43394385298888	0.000289494253539067	0.0183856161775943	469	TGM1,DNASE1L2,UPK1B,LCE3C,EVPL,SFN,EZR,KLF5,PAX8,NKX3-2,SPRR2F,PIP5K1A,NKX6-1,RARA,WT1,CYP26B1,PDZD7,SPRR2E,BMP4,WNT5A,HRNR,BMP2,ANXA4,MET,PPL,LCE5A,LCE2B,GATA3,LRTOMT,DMRT1,CEBPB,PTK7,GRHL2,FGFR2,SDC1,FOXF1,FOXA1,SOX11,GSTM3,CDSN,SKIL,SCEL,GRXCR1,ANXA1,MARVELD2,FLG,SPRR3,NKX6-3,ACVR1,KLF4,XBP1,TCHH,MEN1,UPK2,ATP2B2,CTNNB1,ACTL8,TJP2,NPHS1,DLG5,LCE1C,AKR1C3,CDKN1A,GATA5,TMEM79,TNMD,WNT7B,HIF1A,CPS1,ST14,SPDEF,RAB13,RAB10,EMX1,BMP5,TYMS,CASP3,CDH3,DAB2,SPRR1A,LCE3A,BDH2,PPARG,PRR9,RAPGEF3,MAGI2,KRT14,GDNF,EDNRB,ONECUT1,CRCT1,CASP6,DLX6,CD34,STX2,RAP2B,KRT16,EPHA2,E2F4,FOSL2,ADAM9,PDPK1,ACVR2B,MSN,RILPL2,ZNF703,F11R
GO:0008016	regulation of heart contraction	GO_REGULATION_OF_HEART_CONTRACTION	0.329131929787684	1.61203781738584	0.000329044782994966	0.0201374614594039	205	AGT,PRKACA,PDE5A,TRPM4,CACNA2D4,EPAS1,HSPB7,ANK2,ADRB1,TBX2,ITPR1,CTNNA3,ADRB2,DMPK,SCN5A,CALM3,CACNA2D1,CELF2,RYR2,S100A1,CACNA2D2,ATP1A2,DRD2,HRC,RNF207,KCNJ2,BMP10,FXYD3,TACR3,GJA1,GLP1R,HDAC4,CACNG1,JAK2,CAV3,DMD,UCN,PKP2,FXYD1,PLN,NPR2,SLC8A1,AGTR2,KCNH2,TNNI3,MYH7,CALM1,TMEM65,ADA,CACNA1C,MYL2,GJA5,KCNA5,NKX2-5,ACE2,CACNA1B,TNNT2,KCNIP2,HEY2,CHRM2,DES,IL2,FXYD7,GJC1,GNAO1,SMAD7,TRDN,ATP1A3,SUMO1,ATP2A2,NPFF,SNTA1,ABCC9,KCND3,TH,MYL4,ADM,ATP1B2,JUP
GO:0003013	circulatory system process	GO_CIRCULATORY_SYSTEM_PROCESS	0.293898152206002	1.526897598519	0.000330729494771324	0.0201374614594039	343	P2RY1,AMOT,LRP5,AGT,PTPRM,PPARD,TRPM4,OPRL1,EPB41,PDGFB,ANK2,ADRB1,SERPINF2,SGCD,VIP,NPY1R,TAZ,HSD11B2,ADRB2,PPARA,SCN5A,P2RY2,CACNA2D1,SGCG,ELN,HRH2,RYR2,WNK1,NEDD4L,MYBPC3,GUCY1B3,ATP1A2,DRD2,RENBP,KCNJ2,ADRA2C,ADH5,MYL1,MTHFR,ABR,TACR3,VEGFB,GJA1,GLP1R,HMGCR,GUCY1A3,CHD7,CAV3,TCAP,DMD,ARHGAP35,UCN,PKP2,PLN,NPR2,DOCK4,SLC8A1,AKAP13,AGTR2,TTN,KCNH2,TNNI3,MYH7,PDE2A,GNB3,CX3CL1,DLL4,NCALD,SLC4A5,RAMP3,CACNA1C,MYL2,ESR2,GJA5,MTOR,KCNA5,TBX20,NKX2-5,TEK,ACE2,SOD2,CTNNBIP1,VEGFA,NPY,SRSF1,CACNA1B,CYBA,ENG,SOD1,TBC1D8,TNNT2,MYLK3,FLI1,ADORA2B,MKKS,PTAFR,CD38,GJC1,NPY6R,FGF12,TRDN
GO:0070252	actin mediated cell contraction	GO_ACTIN_MEDIATED_CELL_CONTRACTION	0.448211945135708	1.85602102332455	0.000335026096769643	0.0201374614594039	70	ANK2,SCN5A,CACNA2D1,RYR2,NEDD4L,MYBPC3,KCNJ2,MYL1,GJA1,CAV3,TCAP,DMD,PKP2,TTN,KCNH2,TNNI3,MYH7,TPM2,TMOD1,CACNA1C,MYL2,GJA5,KCNA5,TNNT2,TNNC2,DES,GJC1,FGF12,TNNT3,SNTA1,MYH8,EMP2,MYL4,TNNT1,ACTN2
GO:0030048	actin filament based movement	GO_ACTIN_FILAMENT_BASED_MOVEMENT	0.411081321111716	1.77652313624274	0.000365363536719035	0.02133385389796	89	ANK2,SCN5A,CACNA2D1,RYR2,NEDD4L,MYBPC3,KCNJ2,MYL1,GJA1,MYO9B,CAV3,TCAP,DMD,PKP2,TTN,KCNH2,TNNI3,MYH7,TPM2,WASL,TMOD1,FNBP1L,CACNA1C,MYL2,GJA5,KCNA5,TNNT2,SYNE2,TNNC2,DES,GJC1,FGF12,TNNT3,SNTA1,MYH8,EMP2,MYL4
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL_BY_SARCOPLASMIC_RETICULUM	0.605707609626182	1.97371518803803	0.000367606513987428	0.02133385389796	24	PRKACA,ANK2,CALM3,RYR2,ATP1A2,HRC,AKAP6,DMD,PLN,SLC8A1,CALM1,CACNA1C
GO:0002027	regulation of heart rate	GO_REGULATION_OF_HEART_RATE	0.426454560770709	1.81655314182936	0.000437177581533619	0.0249413515159688	82	AGT,PRKACA,TRPM4,EPAS1,ANK2,ADRB1,CTNNA3,SCN5A,CALM3,CACNA2D1,RYR2,DRD2,HRC,KCNJ2,TACR3,GJA1,CAV3,DMD,PKP2,PLN,SLC8A1,AGTR2,KCNH2,MYH7,CALM1,ADA,CACNA1C,GJA5,KCNA5
GO:0060306	regulation of membrane repolarization	GO_REGULATION_OF_MEMBRANE_REPOLARIZATION	0.572634109580716	1.94033092881015	0.000475450306299717	0.0266727621834141	28	ANK2,SCN5A,CACNA2D1,NEDD4L,RNF207,KCNJ2,GJA1,AKAP6,CAV3,KCNH2,GJA5,KCNA5
GO:0040029	regulation of gene expression epigenetic	GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC	0.330765951540307	1.6067366346294	0.000529564598606583	0.0292215481788485	193	TET1,PHF2,HILS1,HIST1H2AB,ADAR,JARID2,METTL3,WTIP,ZNRD1,HDAC2,PRMT7,TNRC6C,ZCCHC11,TWISTNB,DYDC1,SUV39H1,HIST1H3G,SMAD1,HIST1H3B,EED,TFAP2C,TNRC6A,HMGA1,HELLS,HDAC4,GSK3B,CELF1,SIRT4,HIST1H4F,SMCHD1,CLP1,SIRT5,RRP8,ZFP57,KAT2A,LIN28B,H2AFZ,H3F3A,EZH2,TAF1B,EP300,TNRC6B,AICDA,SRRT,MBD3L1,H2AFV,HNRNPA2B1,HDAC6,RLIM,CTCFL,LIMD1,MOV10,DICER1,HIST1H3E,CNOT8,SPI1,MSL3P1,SMAD3,BAZ2A,WBP2,APOBEC1,ASF1A,MTA1,UBE2B,UBR2,DIRAS3
GO:0043588	skin development	GO_SKIN_DEVELOPMENT	-0.306865718566211	-1.56521120583093	0.000610951302089963	0.0331687432715293	202	CLDN1,TGM1,DNASE1L2,LCE3C,EVPL,SFN,ITGA3,KRT71,SPRR2F,PIP5K1A,CYP26B1,SPRR2E,WNT5A,HRNR,RYR1,PPL,LCE5A,FGF7,LCE2B,FGFR2,CDSN,SCEL,ANXA1,FLG,SPRR3,ALOX12B,TCHH,KRT25,EDAR,CTNNB1,ERRFI1,LCE1C,AKR1C3,EGFR,TMEM79,ST14,CASP3,CDH3,FZD3,SPRR1A,LCE3A,PRR9,KRT76,CRCT1,KRT16,EPHA2,FOSL2,ADAM9,SLC27A4,ACVR1B,CDC42,SLITRK5,CASP14,INHBA,SOX21,PSEN1,KAZN,FLG2,FRAS1,ITGB4,BCL2
GO:0002064	epithelial cell development	GO_EPITHELIAL_CELL_DEVELOPMENT	-0.31574929353715	-1.58059232305218	0.000653611201890445	0.034921512786718	177	DNASE1L2,SFN,EZR,KLF5,PAX8,NKX3-2,NKX6-1,RARA,WT1,PDZD7,BMP4,WNT5A,MET,GATA3,LRTOMT,DMRT1,GRHL2,SDC1,FOXA1,GSTM3,MARVELD2,XBP1,ATP2B2,CTNNB1,TJP2,NPHS1,CDKN1A,TMEM79,TNMD,WNT7B,HIF1A,ST14,SPDEF,RAB13,BMP5,TYMS,RAPGEF3,MAGI2,GDNF,ONECUT1,RAP2B,EPHA2,E2F4,FOSL2,PDPK1,MSN,RILPL2,F11R,INSM1,BASP1,FRMD6,ARHGEF26,CDC42
GO:0044033	multi organism metabolic process	GO_MULTI_ORGANISM_METABOLIC_PROCESS	-0.350949189619667	-1.65767944503864	0.000679991257255264	0.035763290186269	121	RPL24,RPL38,RPL35,MAP2K4,RPL30,RPL9,MAP2K2,RPL3,RPS3A,RPS19,RPS27,RPL4,RPS11,RPL7A,RPS4Y1,RPS8,EIF3L,RPL18,RPS24,RPL18A,UBA52,RPL15,RPS16,RPL5,RPL10A,RPS3,NUP50,RPL22,EIF2AK4,RPS29,RPL26,RPL19,RPS28,RPS5,RPS17,RPL36,RPS6,RPL23A,EIF3G,RPS18,FAU,RPL32,PTBP1,RPLP0,RPL14,NUP210,RPS15,FURIN,SEH1L,RPS13,RPL28,RPS4X,RPL34,NUP43,RPL27
GO:0045165	cell fate commitment	GO_CELL_FATE_COMMITMENT	-0.298824901718	-1.53908334066359	0.000694927032661571	0.0359865291067515	218	PAX7,WNT6,TCF3,TBX6,DLX1,NKX6-1,GBX1,RARA,WT1,CYP26B1,CDON,TGFBR1,BMP4,WNT5A,BMP2,GAP43,GAS1,WNT2B,NEUROG1,GATA3,WNT9A,CEBPB,OLIG1,FGFR2,FOXA1,HOXC10,LEO1,OLIG3,NKX6-3,ACVR1,KLF4,WNT10B,RAG2,CTNNB1,EVX1,ISL2,GATA5,WNT7B,PRDM14,IRF4,RAB10,SOX6,CASP3,SMAD2,PPARG,APC2,FGF13
GO:0061448	connective tissue development	GO_CONNECTIVE_TISSUE_DEVELOPMENT	-0.312240852219168	-1.57053087571557	0.000731012578457816	0.0367314869377333	183	CHI3L1,GDF5,MATN1,PAX7,TIMP1,SULF1,OSR1,RARA,ID4,BMP4,WNT5A,SFRP2,HOXA3,BMP2,ITGB8,CTGF,WNT2B,THBS3,SERPINH1,FOXA1,CYR61,COMP,CRIP1,XBP1,WNT10B,FGF18,BMPR1B,SULF2,CHRDL2,CSF1,DGAT2,SLC25A25,TNMD,MSX2,WNT7B,HIF1A,EIF2AK3,FGF4,BMP5,TYMS,SOX6,LEP,RSPO2,NOV,FGF9,NAMPT,IL17F
GO:0060968	regulation of gene silencing	GO_REGULATION_OF_GENE_SILENCING	0.484230116413118	1.84842134394274	0.00073709190277578	0.0367314869377333	47	TET1,PHF2,UHRF1,ADAR,WTIP,ZNF304,ESR1,HIST1H3G,HIST1H3B,HMGA1,SETDB1,AICDA,NCOR1,LIMD1,HIST1H3E,APOBEC1,ASF1A
GO:0002063	chondrocyte development	GO_CHONDROCYTE_DEVELOPMENT	-0.616152453240058	-1.9947720235025	0.000742050241166328	0.0367314869377333	21	MATN1,SULF1,SFRP2,SERPINH1,FGF18,BMPR1B,SULF2,MSX2,EIF2AK3
GO:0033561	regulation of water loss via skin	GO_REGULATION_OF_WATER_LOSS_VIA_SKIN	-0.644324556147466	-2.0009201838664	0.00078014952865966	0.0380577291807017	18	CLDN1,SFN,CYP26B1,HRNR,FLG,ALOX12B,TMEM79
GO:0002066	columnar cuboidal epithelial cell development	GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DEVELOPMENT	-0.475878354296687	-1.86154566012924	0.00081060998401297	0.0384995148848206	45	KLF5,NKX3-2,NKX6-1,RARA,PDZD7,BMP4,WNT5A,LRTOMT,ATP2B2,CDKN1A,HIF1A,SPDEF,BMP5,TYMS
GO:0009896	positive regulation of catabolic process	GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS	0.278937104243276	1.46126901614984	0.00081208127059485	0.0384995148848206	372	CPEB3,LRSAM1,WDFY3,BAD,RNF144B,FLCN,AKT2,CDC26,RNF40,FBXW7,OSBPL7,TRIB2,ATG14,TP53INP2,ATPIF1,PRICKLE1,CSNK2A1,VIP,PSMD11,ADRB2,PPARA,PPP2R3A,EDEM2,TNRC6C,ULK1,LRRK2,CALCOCO2,PSMD2,PSMC6,TPCN1,NEDD4L,RAB12,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,PCSK9,PINK1,FZR1,GJA1,USP13,VPS11,BTRC,GSK3B,CAV3,PTEN,CDK5RAP3,PRKAA2,ANAPC1,RAB3GAP1,PIP4K2C,IRS1,GCK,PSMC5,PSMB7,PSME4,GORASP1,TRIM13,DNAJB2,SGTA,PIP4K2B,RNF144A,SCOC,MEFV,TNRC6B,HAMP,RNF125,FOXO1,ANAPC11,RNF152,TNF,ARIH2,PSMA8,CDKN1B,PARK7,SOCS4,SOX17,CDK1,PSMD8,TRIM32,VCP,PSMB10,GGA3,APC,P2RX7,RHBDD3,TRIB3,SOX9,TFEB,DLGAP5,CNOT8,RDX,PSMD3,PSMB1,BAG6,CSNK1A1,HMGB1,SMAD7,OAZ1,ENDOG,RHBDD1,SUMO2,PSMA5,SUMO1,EPM2A,PSMB9,USP5,PRKCE,NDUFA13,UVRAG,EGF,PHKG2,CHFR,ESPL1,CNOT1,CBFA2T3,AMBRA1,ASB9,APOA5,PSMD6
GO:0060537	muscle tissue development	GO_MUSCLE_TISSUE_DEVELOPMENT	0.302561267429107	1.51942307038143	0.000841805348701677	0.0388146934316537	252	XK,AGT,UBE4B,SRPK3,ITGA8,DNER,TBX2,CFLAR,ANKRD2,GTF3C5,MSC,SGCD,TAZ,NDRG4,HLX,SGCG,TSC1,RYR2,SVIL,NDUFV2,MYBPC3,BCL9L,HIVEP3,BMP10,SMAD1,PLAGL1,EYA1,XIRP2,CAV3,OBSL1,PTEN,NPRL3,TCAP,PKP2,PRKAR1A,PLN,ZNF689,SLC8A1,AKAP13,AGTR2,SMYD1,TTN,KAT2A,TNNI3,MYH7,KLHL31,EGLN1,SIX1,SHH,DLL4,EP300,MYLK,TCF21,MYL2,GJA5,MTOR,TBX5,TBX20,S1PR1,NKX2-5,EMD,FHL2,RXRA,NCOR1,CDK1,VEGFA,HOMER1,FHOD3,ENG,MEF2D,TNNT2,SOX9,MYLK3,LEMD2,HEY2,LRRC10,GJC1,FLNB,SMAD7,GPCPD1,MARCKS,PROX1,TBX3,MED1,HOXD10,VGLL2,NR2F2,NOX4,MEF2C,SRF,SGCB,MAFF,DSP,PTCD2,TGFBR3,P2RX2,SAP30,ACTN2,SMO,IGFBP5,FOXC2,RARB,PHOX2B,MYOCD,ANKRD33
GO:0061136	regulation of proteasomal protein catabolic process	GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS	0.336489465071358	1.60430626529008	0.000850467757266497	0.0388146934316537	167	GNA12,PRKACA,PCID2,RNF144B,RNF40,FBXW7,UBQLN4,OSBPL7,TRIB2,PRICKLE1,CSNK2A1,LRRK2,N4BP1,PSMC6,RAD23A,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,PINK1,BTRC,GSK3B,PTEN,PSMC5,GORASP1,TLK2,DNAJB2,SGTA,SHH,RNF144A,RNF125,ANAPC11,OPHN1,ARIH2,PARK7,SOCS4,VCP,APC,TRIB3,DLGAP5,PBK,BAG6,CSNK1A1,SMAD7,SUMO2,USP14,KLHL22,SUMO1,TPR,MAD1L1,USP5,UBXN1,COMMD1,CHFR,ESPL1
GO:0018149	peptide cross linking	GO_PEPTIDE_CROSS_LINKING	-0.448032510809128	-1.82379459746636	0.000863361657654383	0.0388146934316537	54	TGM1,LCE3C,EVPL,SPRR2F,EPB42,SPRR2E,LCE5A,LCE2B,ANXA1,SPRR3,SPOCK2,LCE1C,ABCA7,SPRR1A,LCE3A,PRR9,CRCT1,DCN,THBS1,TGM7
GO:0061035	regulation of cartilage development	GO_REGULATION_OF_CARTILAGE_DEVELOPMENT	-0.441103568665128	-1.81545649522629	0.000864855022986936	0.0388146934316537	57	GDF5,NKX3-2,RARA,EFEMP1,TGFBR1,BMP4,WNT5A,BMP2,CTGF,WNT9A,CYR61,CTNNB1,FGF18,BMPR1B,SOX6,LEP,PTHLH,SCIN
GO:0099623	regulation of cardiac muscle cell membrane repolarization	GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION	0.628746292855337	1.92403741322925	0.000963605366540657	0.0426775745233665	19	ANK2,SCN5A,CACNA2D1,RNF207,GJA1,CAV3,KCNH2,GJA5,KCNA5
GO:0061061	muscle structure development	GO_MUSCLE_STRUCTURE_DEVELOPMENT	0.272278831455936	1.43643723825717	0.000992248062015504	0.0429363940934375	399	LAMA2,XK,AGT,UBE4B,SRPK3,FBXO40,SGCA,OBSCN,EPAS1,ITGA8,ANK2,DNER,TBX2,LDB3,CFLAR,ANKRD2,GTF3C5,MSC,SGCD,TAZ,PPP2R3A,SMTN,HLX,SGCG,TSC1,RYR2,SVIL,FHL3,CACNA2D2,CAPN3,MYBPC3,BCL9L,HIVEP3,BMP10,MKL2,CDH2,BARX2,ZFHX3,QKI,LMOD1,CTF1,LMOD3,PLAGL1,XIRP2,HMGCR,USP2,MKL1,GSK3B,SMARCD3,CAV3,OBSL1,REST,TMEM204,TCAP,DMD,PKP2,PRKAR1A,ZBTB42,MURC,ZNF689,SLC8A1,AKAP13,AGTR2,NFATC4,MYPN,SMYD1,TTN,KAT2A,TNNI3,MYH7,KLHL31,DYRK1B,EGLN1,SIX1,SHH,DLL4,EP300,MYLK,TMOD1,TCF21,MYL2,UNC45B,MTOR,TBX5,TBX20,S1PR1,NKX2-5,EMD,FLNC,FHL2,RXRA,NCOR1,CDK1,VEGFA,HOMER1,FHOD3,MEF2D,TNNT2,SOX9,MYLK3,CNTFR,LEMD2,TANC1,HEY2,SORT1,LRRC10,TMEM8C,PAX3,FLNB,SMAD7,FGF6,LAMA5,CFL2,FOXO4,CSRP2,ATP2A2,ASF1A,GPCPD1,PROX1,TBX3,MSX1,MED1,HOXD10,VGLL2,ADM,NR2F2,NOX4,MEF2C,UTRN,SRF,PLEKHO1,ITGB1BP2,TWIST1,SGCB,MAFF,DSP,PTCD2,TGFBR3,P2RX2,SAP30,CASQ2,ACTN2,CHODL,SMO,IGFBP5,FOXC2,RARB,PHOX2B,MYOCD,ANKRD33
GO:1903522	regulation of blood circulation	GO_REGULATION_OF_BLOOD_CIRCULATION	0.296331975526465	1.50255679695439	0.000994961003947749	0.0429363940934375	273	P2RY1,AGT,PRKACA,PTPRM,PPARD,PDE5A,TRPM4,CACNA2D4,EPAS1,HSPB7,ANK2,ADRB1,TBX2,ITPR1,CTNNA3,VIP,NPY1R,ADRB2,DMPK,SCN5A,P2RY2,CALM3,CACNA2D1,CELF2,HRH2,RYR2,S100A1,CACNA2D2,ATP1A2,DRD2,HRC,RNF207,KCNJ2,BMP10,ADRA2C,FXYD3,TACR3,GJA1,GLP1R,HMGCR,HDAC4,CACNG1,JAK2,CAV3,DMD,UCN,PKP2,FXYD1,PLN,NPR2,DOCK4,SLC8A1,AGTR2,KCNH2,TNNI3,MYH7,CX3CL1,CALM1,TMEM65,ADA,CACNA1C,MYL2,ESR2,GJA5,KCNA5,NKX2-5,ACE2,CACNA1B,TNNT2,KCNIP2,HEY2,CHRM2,DES,PTAFR,IL2,FXYD7,CD38,GJC1,GNAO1,SMAD7,TRDN,ATP1A3,SUMO1,ATP2A2,NPFF,SNTA1,SCPEP1,ABCC9,KCND3,TH,MYL4,ADM,PRKCQ,ATP1B2
GO:0045669	positive regulation of osteoblast differentiation	GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION	-0.439717103321034	-1.80280015792501	0.00102477682638003	0.0436632759189265	56	PRKD1,ID4,BMP4,SFRP2,BMP2,NPNT,CEBPB,CYR61,SOX11,ACVR1,WNT10B,CTNNB1,BMPR1B,IL6ST,CEBPA,MSX2,WNT7B
GO:0050818	regulation of coagulation	GO_REGULATION_OF_COAGULATION	-0.382001026673984	-1.69990710272681	0.00105216395052491	0.0438967136150235	85	VTN,PRKCA,PROCR,ANO6,FAP,C1QTNF1,ANXA5,SERPING1,ANXA2,F7,HPSE,F2,PLAUR,ADAMTS18,SERPINB2,S100A9,PROS1,HS3ST5,CD34,STX2,THBS1,F2R,TXK,ABAT,EDN1,NFE2L2,SCARA5,F3,PSEN1,STAB2,SERPINC1,THBD,ZAP70
GO:0014013	regulation of gliogenesis	GO_REGULATION_OF_GLIOGENESIS	-0.382547062948593	-1.70902075653819	0.00105633802816901	0.0438967136150235	87	DLX1,UFL1,NKX6-1,SPINT1,EFEMP1,SLC45A3,ID4,BMP4,BMP2,TNFRSF21,PRKCI,SOX11,TSPO,PRMT5,CLCF1,CTNNB1,TP73,IL6ST,CSF1,F2,EMX1,MAG,CERS2,PPARG
GO:0001738	morphogenesis of a polarized epithelium	GO_MORPHOGENESIS_OF_A_POLARIZED_EPITHELIUM	-0.559756346933183	-1.91857540369896	0.00125376679937532	0.0514655981304551	26	C5orf42,EZR,TRAF3IP1,WNT5A,PTK7,FOXF1,DLG5,RAB10,FZD3,MSN,WNT9B
GO:0019932	second messenger mediated signaling	GO_SECOND_MESSENGER_MEDIATED_SIGNALING	0.342868404577994	1.60031992152481	0.00128177019209687	0.0519811863445552	144	AGT,PRKACA,RCAN2,ANK2,ITPR1,RAPGEF4,DMPK,LRRK2,NUDT4,CALM3,RYR2,GUCY1B3,ATP1A2,HRC,DGKQ,ADCYAP1R1,GLP1R,GUCY1A3,HDAC4,PLCE1,AKAP6,RAPGEF2,DMD,ADCY7,CXCR3,PLN,GPRC6A,ADCY5,GCK,PPP1R9A,SLC8A1,AGTR2,NFATC4,PDE2A,LAT2,CALM1,NCALD,PPP3R1,CACNA1C,ADCY8,ADCY9,SELP,ADCY4,SOX9,PDE7A,NMUR2,PLCG1,CD36,MCTP1,BTK,ATP2A2,CAMKK2,PRKG1
GO:0051216	cartilage development	GO_CARTILAGE_DEVELOPMENT	-0.329374799719017	-1.59128414136672	0.0012985103880831	0.0520331662653301	139	CHI3L1,GDF5,MATN1,PAX7,TIMP1,SULF1,OSR1,RARA,BMP4,WNT5A,SFRP2,HOXA3,BMP2,ITGB8,CTGF,WNT2B,THBS3,SERPINH1,CYR61,COMP,WNT10B,FGF18,BMPR1B,SULF2,CHRDL2,MSX2,WNT7B,HIF1A,EIF2AK3,FGF4,BMP5,TYMS,SOX6,RSPO2,NOV,FGF9,IL17F
GO:0043062	extracellular structure organization	GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION	-0.273933515584144	-1.45715311448303	0.00132992871582083	0.0526651771465049	283	VTN,MMP1,CMA1,MATN1,TIMP1,ADAMTS3,ITGA3,SULF1,CCDC80,KDR,AGRN,SPINT1,WT1,LAMA1,TGFBR1,MFAP2,LAMA3,SFRP2,ITGB8,FMOD,LAMC2,KLK7,CTGF,TNFRSF11B,NPNT,HTRA1,SERPINH1,SERAC1,COL6A2,ADAM15,FOXF1,CYR61,CREB3L1,COMP,SNCA,DMP1,FLRT2,ANXA2,DSPP,SPOCK2,HAS1,TNXB,MMP12,SULF2,NPHS1,B4GALT7,RIPK1,MMP20,ABI3BP,RIPK3,ICAM4,COL9A3,TLL1,COL7A1,SPARC,LTBP2,CTSK,TEX14,CDH1,CAPN1,CAPN2,DCN,MPZL3,TIMP2,THBS1,KLK2,F11R
GO:0086001	cardiac muscle cell action potential	GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.511455198407131	1.82740671859408	0.0013815669878204	0.0540738893139936	35	ANK2,SCN5A,CACNA2D1,RYR2,NEDD4L,ATP1A2,KCNJ2,GJA1,CAV3,DMD,PKP2,SLC8A1,KCNH2,CACNA1C,GJA5,KCNA5,GJC1,FGF12,SNTA1
GO:0042776	mitochondrial atp synthesis coupled proton transport	GO_MITOCHONDRIAL_ATP_SYNTHESIS_COUPLED_PROTON_TRANSPORT	0.659788763734598	1.89588155351359	0.00146842878120411	0.0568130031900349	15	ATP5L,ATP5A1,ATP5G2,ATP5D,ATP5O,ATP5B,ATP5G3
GO:1903362	regulation of cellular protein catabolic process	GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS	0.295531056506714	1.48411827160168	0.00165123356860714	0.0627609616300473	252	GNA12,PRKACA,PCID2,RNF144B,CDC26,RNF40,FBXW7,UBQLN4,OSBPL7,TRIB2,ATPIF1,PRICKLE1,CSNK2A1,PSMD11,LRRK2,N4BP1,PSMD2,PSMC6,RAD23A,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,PCSK9,PINK1,FZR1,VPS11,SUFU,BTRC,GSK3B,CAV3,PTEN,CDK5RAP3,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,TLK2,DNAJB2,SGTA,SHH,RNF144A,RNF125,ANAPC11,OPHN1,ARIH2,PSMA8,PARK7,SOCS4,CDK1,PSMD8,VCP,PSMB10,APC,TRIB3,DLGAP5,PBK,RDX,PSMD3,PSMB1,BAG6,CSNK1A1,SMAD7,SUMO2,USP14,PSMA5,KLHL22,SUMO1,TPR,PSMB9,MAD1L1,USP5,UBXN1,COMMD1,EGF,CHFR,ESPL1
GO:0010608	posttranscriptional regulation of gene expression	GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION	0.267596743425467	1.41130188698471	0.00165945501636192	0.0627609616300473	398	LSM14B,CPEB3,TRAP1,PTCD3,LARP4B,ADAR,METTL3,DDX3X,RC3H2,PCID2,AKT2,MAPKAPK2,EIF2B5,DCP2,WTIP,SCGB1A1,NPM1,MKNK1,C1QBP,PRR16,ATG14,NCBP1,BARHL2,VIP,PSMD11,APP,RMND1,PAIP2B,TNRC6C,ZCCHC11,ESR1,SAMD4A,TSC1,PSMD2,PSMC6,CPEB2,TACO1,SMAD1,MIF4GD,QKI,PINK1,TNRC6A,LARS2,EXOSC4,EXOSC7,FAM129A,CELF1,CLP1,UCN,DDX39B,PSMC5,PSMB7,MTG1,PSME4,CNOT6L,LIN28B,ABCF1,IARS2,UNK,MAPKAPK5,TIA1,KHDRBS1,EP300,GCNT2,PAIP2,TNRC6B,EIF4E2,THRAP3,MTOR,YTHDF2,DAPK3,NCBP2,TNF,SRRT,PSMA8,RXRA,NCOR1,RPS14,MAPK1,HNRNPA2B1,EXOSC3,PSMD8,PSMB10,LIMD1,MOV10,DICER1,HSPB1,EIF3J,DCP1A,CNOT8,METAP1,ANP32A,EIF1B,IMPACT,PSMD3,EIF2B4,PSMB1,PTAFR,SMAD3,PASK,YBX1,IMP3,GIGYF2,PSMA5,TPR,PSMB9,APOBEC1,EIF4E3,EEFSEC,EIF4G1,RBM8A,EIF2AK1,CNOT1,NSUN4,EIF2S1,PSMD6,EIF3D,MPV17L2,LARP1,SERBP1,YRDC,PSMB3,PSMB6,PIWIL3,NUP214,PSMD1,DIO2,IREB2,PER1,SEPSECS,IGFBP5,ZNF706,RBM3,PRORSD1P
GO:0032940	secretion by cell	GO_SECRETION_BY_CELL	-0.245232700546085	-1.36930680503626	0.00172637030643073	0.0645662494605093	452	STEAP3,SLC1A6,CHI3L1,MRGPRX2,SERPINA3,CFTR,STX19,TIMP1,HAP1,TYRO3,P2RX1,SCG2,SMPD3,CCL3,SYT4,CCL19,SNAP25,ANXA3,NLGN1,TRIM72,UBE2Q1,TMED10,ARHGAP44,TRAF3IP2,SYN1,RAB31,ILDR2,ARL4D,RIMS4,SYTL1,PDIA4,CTGF,SLC1A1,FGF7,GATA3,SYT17,SCFD1,TRIM9,POTEKP,SERPING1,CREB3L1,ANXA1,SLC38A2,MMRN1,CANX,RPH3A,PDZD11,EXOC5,SCRN1,S100A12,C2CD4D,MIA3,BRSK2,SYN3,SLC17A7,NR4A3,STXBP3,TMEM79,PRSS12,SNAP23,PCLO,EIF2AK3,RAB13,LEP,STX11,SYT6,SLC18A2,ORM1,VPS33A,SMAD2,CDK5,VAMP8,SPARC,UNC13B,SCIN,ABCA1,LIN7B,LTBP2,RARRES2,GPR119,PROS1,LAT,HGF,KCNB1,SLC30A8,NLRP3,F5,SYT5,STX2,STXBP1,STXBP5L,THBS1,GAL,ACVR2B,RALA,CARTPT,CASK,TMSB4X,SLC32A1,POU2F2,CYB5R4,VPS18,TLR2,MON1A,GCGR,TMF1,EDN1,VPS45,VTCN1,FCER1A,GPAM,LLGL1,SYTL5
GO:0071294	cellular response to zinc ion	GO_CELLULAR_RESPONSE_TO_ZINC_ION	-0.640675808456146	-1.92506958598815	0.00181829988960322	0.067257114597851	16	MT1M,MT1E,MT2A,TSPO,MT1A,MT1F,MT1G
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	GO_ADAPTIVE_IMMUNE_RESPONSE_BASED_ON_SOMATIC_RECOMBINATION_OF_IMMUNE_RECEPTORS_BUILT_FROM_IMMUNOGLOBULIN_SUPERFAMILY_DOMAINS	-0.331835552331722	-1.58336476487417	0.00190438986278627	0.0696736569115227	129	RAET1E,GCNT3,C3,CD55,C4A,C2,CFI,IL18,C9,C4BPA,GATA3,MASP2,HLA-DRB5,C1RL,SERPING1,C1R,C1S,C4BPB,EXOSC6,IRF7,IRF4,IGHG4,IGHG2,IGHG1,MBL2,FAS,C5,IGHD,IGKC,RNF8,POU2F2,SEMA4A,IGLL1,IGLC1,HLA-DRB1,DLG1,GNL1,NBN,SWAP70,IL4R,CD46
GO:0007507	heart development	GO_HEART_DEVELOPMENT	0.261058891613909	1.38834580125374	0.00193944618036849	0.0696736569115227	434	AGT,UBE4B,PPARD,NRP1,PDGFB,ANK2,TBX2,HDAC9,PRICKLE1,DLC1,SGCD,LRP6,ALPK3,DVL2,NPY1R,TAZ,PPARA,NDRG4,SCN5A,VLDLR,SGCG,C2CD3,TSC1,GLI2,MEGF8,RYR2,HAND2,NDUFV2,NDST1,MYBPC3,CRKL,TSC2,YAP1,BMP10,NACA,SMAD1,GYS1,RBM20,IFT172,EYA1,NKX3-1,XIRP2,VEGFB,GJA1,CHD7,PLCE1,SUFU,SMARCD3,CAV3,OBSL1,PTEN,REST,DCTN5,ADAM19,NPRL3,TCAP,PKP2,PRKAR1A,PLN,ADIPOR2,SLC8A1,TGFBR2,MED12,AKAP13,AGTR2,NFATC4,SMYD1,TTN,KAT2A,TNNI3,MYH7,EGLN1,SIX1,SHH,CRELD1,RAF1,TMEM65,DLL4,ERG,DAND5,EP300,ERBB4,LTBP1,CACNA1C,MYL2,GJA5,MTOR,ZMIZ1,TBX5,TBX20,LUZP1,S1PR1,NKX2-5,TEK,NPY5R,FAT4,FHL2,RXRA,MAPK1,SOX17,CDK1,VEGFA,ATF2,PTCH1,FHOD3,ENG,MEF2D,APLNR,TNNT2,SOX9,MYLK3,SETDB2,LEMD2,WNT11,HEY2,MKKS,LRRC10,BCOR,GJC1,MOSPD3,GAB1,SMAD7,SMAD3,FGF12,JMJD6,PRKDC,CAD,FGF8,FOXJ1,MRE11A,TCF25,MARCKS,PLXND1,PROX1,NTRK3,TBX3,XIRP1,MSX1,MED1,NOTO,GATA2,TH,ADM,NOX4,MEF2C,SRF
GO:0033002	muscle cell proliferation	GO_MUSCLE_CELL_PROLIFERATION	0.630528210507183	1.87311751060303	0.00195283439964291	0.0696736569115227	17	TK1,AGT,NDRG4,BMP10,SMAD1,PRKAR1A,NKX2-5,RXRA,NAA35
GO:0001501	skeletal system development	GO_SKELETAL_SYSTEM_DEVELOPMENT	-0.246953169876499	-1.37158454109389	0.00196642822536977	0.0696736569115227	427	CHI3L1,GDF5,MATN1,PAX7,TIMP1,PPIB,HOXA6,RPL38,RBP4,NAB2,SULF1,NKX3-2,DLX1,OSR1,IRX5,RARA,CYP26B1,RDH10,TGFBR1,IGFBP4,BMP4,WNT5A,SFRP2,HOXA3,BMP2,RYR1,ITGB8,ALPL,CTGF,TNFRSF11B,T,HOXA7,WNT2B,ANO6,WNT9A,THBS3,SERPINH1,GRHL2,FGFR2,PAPPA2,HAPLN3,CYR61,SOX11,HOXC10,MTHFD1L,COMP,GDF10,ANXA2,DSPP,PAPSS2,WNT10B,SGPL1,CTNNB1,FGF18,BMPR1B,SULF2,CHRDL2,NLE1,WDR19,SERP1,MSX2,WNT7B,HIF1A,EIF2AK3,FGF4,CDH11,BMP5,TYMS,SOX6,LEP,PTHLH,PRKRA,SMAD2,RSPO2,NOV,TLL1,SPEF2,WHSC1,SPARC,FGF9,EXT1,IL17F,DLX6,CMKLR1,VKORC1,EPHA2,WWOX,ACVR2B,WNT9B,TULP3,HOXB8,RHOA,EXTL1,NODAL,SLC39A1,EDN1,FAM20C,SPNS2,TBX4,TEAD4,MYCN,ARSE,PTGER4,RASSF2,PLXNB1,MGP,DLG1,COL12A1,RAB23,MATN3,AXIN1
GO:0016266	o glycan processing	GO_O_GLYCAN_PROCESSING	-0.435890771232022	-1.75976405530897	0.00201599202663828	0.0706857204340046	52	GCNT3,MUC2,GALNT12,MUC7,MUC16,MUC5B,B3GNT6,B3GNT5,MUC1,GCNT1,MUC6,GALNT5,B4GALT5,GALNT10,GXYLT2,MUC21,GALNT1,C1GALT1C1
GO:0034122	negative regulation of toll like receptor signaling pathway	GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	-0.57410874779576	-1.88218750004951	0.00223238712219037	0.0774661345700286	22	SMPDL3B,TYRO3,LY96,SARM1,NLRP6,IRF4,IRAK3,TLR9,PDPK1
GO:0072657	protein localization to membrane	GO_PROTEIN_LOCALIZATION_TO_MEMBRANE	-0.254313285835696	-1.38407578091134	0.0022834818972158	0.0784306129186571	349	RPL24,SCN3B,SRP72,RPL38,BBC3,EZR,PIP5K1A,NLGN1,AGRN,RPL35,SEC63,S100A10,RAB31,PRKG2,PIGW,RPL30,AMN,KRT18,RPL9,PRKCI,RPL3,RPS3A,TMED2,ITGB1BP1,RPS19,RPS27,TIMM10,RPL4,ANXA2,TRAM1,TIMM9,RPS11,SPTBN4,RPL7A,SSR1,RPS4Y1,PDZD11,RAB38,RPS8,SH3GLB1,RPL18,WDR19,EGFR,TSPAN15,SSR2,RAB3GAP2,REEP1,RPS24,TULP1,RPL18A,UBA52,RAB13,RAB10,TNFRSF1A,RPL15,ADIPOQ,RPS16,MPP5,RPL5,GOLGA7,DPP6,CDK5,RPL10A,RPS3,TULP2,TSPAN5,DENND4C,LIN7B,FGF13,RPL22,SRP54,GCC2,MAGI2,PIGR,RPS29,CDH1,RPL26,RPL19,KCNB1,PICK1,INPP5K,STXBP1,SRP14,BAX,GRIN3B,GRIK2,RILPL2,RPS28,F11R,WRB,RPS5,HSP90AA1,RPS17,CHM,TULP3
NA	retrograde vesicle mediated transport golgi to er	GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ER	-0.389255498875441	-1.67967187153716	0.00233823359185091	0.0794999421229309	72	KIF2C,KIF18A,KIF5A,COPB1,TMED10,KDELR3,TMED3,BNIP1,SCFD1,TMED2,LMAN2,KIF3A,SCYL1,COPG2,SURF4,KDELR2,ERGIC2,COPB2,STX18,TMEM115,PICK1,ATP9A,KIF4A,KIF3C
GO:0061458	reproductive system development	GO_REPRODUCTIVE_SYSTEM_DEVELOPMENT	-0.248645975186929	-1.36728623072677	0.00243172988232663	0.0813952930144135	384	CCNF,KRT8,LHX9,KIF18A,KRT19,PTGIS,LHX4,RBP4,PLCD1,TYRO3,AMHR2,OSR1,IRX5,RARA,SPINT1,WT1,UBE2Q1,RDH10,TGFBR1,ID4,BMP4,WNT5A,CUL7,SFRP2,NUPR1,ITGB8,FGF7,WNT2B,HTRA1,MGST1,GATA3,DMRT1,CEBPB,GRHL2,FSHR,FGFR2,SDC1,ADAM15,TMED2,FOXA1,CYR61,UTF1,CRIP1,ANXA1,FANCF,MEN1,INSL3,SGPL1,REC8,CTNNB1,BMPR1B,BOK,SLIT3,CEBPA,AKR1C3,WDR19,EGFR,STAR,WNT7B,HIF1A,ROBO2,ST14,RAB13,BMP5,LEP,COL9A3,STK3,PPARG,FGF9,FAS,MEA1,PRKACG,ETV2,DCN,SOX15,ADCYAP1,BAX,HMGB2,HSD17B10,AHR,ALKBH1,WNT9B,TTPA,PKD2,NODAL,TMF1,BASP1,AFP,FSHB,GPR149,JUNB,FOXO3,DLG1,INHBA,RPS6,FBXW8,SOCS3,SIRT1,ARID4A,HOXB13,LRRC6,ESRRB,STRA6,FOXL2,IL10,MMP19,MMP14,BCL2,PLA2G4A
GO:0002449	lymphocyte mediated immunity	GO_LYMPHOCYTE_MEDIATED_IMMUNITY	-0.331597951391869	-1.56627547319579	0.00245282560652792	0.0813952930144135	121	RAET1E,GCNT3,C3,CD55,C4A,C2,CFI,C9,C4BPA,GATA3,MASP2,HLA-DRB5,C1RL,SERPING1,C1R,C1S,C4BPB,EXOSC6,IRF7,ULBP3,IGHG4,CEBPG,IGHG2,IGHG1,MBL2,RAET1G,FAS,C5,IGHD,IGKC,RNF8,POU2F2,IGLL1,IGLC1,HLA-DRB1,DLG1,GNL1,ULBP2,NBN,SWAP70,IL4R,CD46
GO:0032543	mitochondrial translation	GO_MITOCHONDRIAL_TRANSLATION	0.370164550824525	1.62903175664182	0.0024704581576947	0.0813952930144135	99	TARS2,PTCD3,AURKAIP1,GFM1,MRPL4,MRPL16,NDUFA7,MRPL41,MRPL14,EARS2,MRPL19,MRPS15,MRPL53,MTIF3,MRPL15,MRPL27,MRPS28,MRPL24,MRPL35,MRPL20,MRPL17,MRPL12,MRPL37,MRPL51,MRPS22,MRPS18B,MRPL39,MRPS25,QRSL1,MRPL46,MRPL18,MRPS30,MRRF,MRPS17,MRPL28,MRPL30,AARS2,MRPS7,MRPL54,MRPS26,MRPL10,MRPL52
GO:0086003	cardiac muscle cell contraction	GO_CARDIAC_MUSCLE_CELL_CONTRACTION	0.541349828348716	1.81704732876492	0.00249070563888431	0.0813952930144135	27	ANK2,SCN5A,CACNA2D1,RYR2,NEDD4L,KCNJ2,GJA1,CAV3,PKP2,KCNH2,CACNA1C,GJA5,KCNA5,GJC1,FGF12,SNTA1
GO:1903317	regulation of protein maturation	GO_REGULATION_OF_PROTEIN_MATURATION	-0.379745141963061	-1.65519044238223	0.0025337641507241	0.0815533244214379	76	VTN,CFB,C3,CD55,C4A,C2,CFI,CFH,C9,C4BPA,GAS1,RFX4,SERPING1,CHAC1,C4BPB,MASP1,MAGEA3,C5AR1,PROS1,ASTL,C5,IFT52,THBS1,TMEM59
GO:0002062	chondrocyte differentiation	GO_CHONDROCYTE_DIFFERENTIATION	-0.418075961104116	-1.72068142949133	0.00254904638354044	0.0815533244214379	57	GDF5,MATN1,SULF1,OSR1,BMP4,SFRP2,BMP2,WNT2B,SERPINH1,WNT10B,FGF18,BMPR1B,SULF2,MSX2,EIF2AK3,NOV,FGF9
GO:0009225	nucleotide sugar metabolic process	GO_NUCLEOTIDE_SUGAR_METABOLIC_PROCESS	-0.501549076575477	-1.82521011275223	0.00259297016976198	0.0815533244214379	33	AMDHD2,GFPT2,UAP1,GUK1,PGM3,UGDH,EXTL2,FUT8,SLC35A3,DPAGT1,PMM1,UGGT2,TGDS,GMDS
GO:0003229	ventricular cardiac muscle tissue development	GO_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.478061549832822	1.76147047683695	0.00260153201329672	0.0815533244214379	40	UBE4B,RYR2,MYBPC3,BMP10,PKP2,TNNI3,MYH7,DLL4,MYL2,TBX5,NKX2-5,RXRA,TNNT2,HEY2,SMAD7,MARCKS,PROX1,TBX3,MED1,DSP,PTCD2,TGFBR3,FOXC2
GO:0006954	inflammatory response	GO_INFLAMMATORY_RESPONSE	-0.245739428951676	-1.36117456916034	0.00261668420603544	0.0815533244214379	416	TNFRSF8,CHI3L1,ASS1,SERPINA3,C3,C4A,LXN,P2RX1,SCG2,APOA2,CCL3,GSDMD,CCL19,BDKRB1,AOX1,IL17B,IL18,CYP26B1,FFAR3,PRKD1,IGFBP4,BMP2,HP,NUPR1,MMP25,TNFRSF21,LTB4R,TNFRSF11B,LY96,ANO6,GATA3,CEBPB,ALOX15,SDC1,HLA-DRB5,IL27,OPRM1,ANXA1,NFKBIZ,TACR1,ACVR1,PLA2G2D,CXCL1,BMPR1B,STAT3,S100A12,NLRP6,CD5L,CNR2,PYCARD,CCL21,RIPK2,CSF1,SLC7A2,CHUK,IL36B,HIF1A,SNAP23,F2,SAA1,TNFRSF1A,HRH4,TLR10,ORM1,C5AR1,IKBKG,CYP4F11,S100A9,BDKRB2,RARRES2,TNFRSF25,IL17F,IL24,IL17D,LAT,MBL2,FAS,C5,NLRP3,IL5,PTGS1,TLR9,THBS1,NOD1,KRT16,GAL,HMGB2,PXK,F11R,F2R,PARP4,CCL4,IL2RA,TLR2,MIF,IL25,NFE2L2,HLA-DRB1,CCL18,IL1RAP,ELANE,IFI16,AFAP1L2,IL36G,F3,CXCL5
GO:1904063	negative regulation of cation transmembrane transport	GO_NEGATIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT	0.437009896558141	1.71787665565869	0.00264342359076945	0.0816308606103667	54	AGT,OPRL1,DRD4,CALM3,NEDD4L,ATP1A2,DRD2,PCSK9,CAV3,PLN,KCNH2,CALM1,HAMP,KCNRG,ANK3,SLC30A1,FGF12,TRDN,SUMO1,PRKCE,COMMD1,CASQ2,ACTN2,GSTO1,DRD3,KCNAB1,KCNQ1,CAB39,TGFB1,CAMK2D,CLIC2,EPO,CALM2,SLN,KCNE2
GO:0042476	odontogenesis	GO_ODONTOGENESIS	-0.351675767373654	-1.60705793723046	0.00287288095351156	0.0879101571774538	99	FAM20A,SLC34A1,AMBN,WNT6,DLX1,OSR1,AQP1,BMP4,BMP2,AQP3,ALPL,HTRA1,TUFT1,FGFR2,SDC1,EDAR,CTNNB1,CSF1,MMP20,PAX9,MSX2,FGF4
GO:0051897	positive regulation of protein kinase b signaling	GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING	-0.373832652185687	-1.6334614900818	0.00292961938198982	0.0888387282862858	77	CHI3L1,CCL3,TNFSF11,CCL19,KIAA1161,TGFBR1,FAM110C,ANGPT1,GATA3,C1QTNF1,ITGB1BP1,F7,CCL21,HPSE,AKR1C3,MST1R,EGFR,LEP,STK3,TNFAIP8L3
GO:0060575	intestinal epithelial cell differentiation	GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION	-0.622797782394792	-1.87135061646572	0.00298720696149101	0.0897762377890958	16	KLF5,NKX3-2,CDKN1A,GATA5,HIF1A,SPDEF,TYMS
GO:0007588	excretion	GO_EXCRETION	-0.456354097336256	-1.7583750058202	0.00311645217703242	0.0928316639636383	42	SCTR,ATP6V1B1,AQP3,AMN,CLDN16,CLCNKB,UMOD,TACR1,KIRREL,NPHS1,CHRNB2,UNC13B,SCNN1G,SCNN1B,NPHP1,CLCN5,AQP9
GO:0010575	positive regulation of vascular endothelial growth factor production	GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION	-0.538498001157153	-1.82665241679607	0.00320801564456944	0.0947208829791294	25	C3,SULF1,SULF2,IL6ST,HPSE,HIF1A,EIF2AK3,C5AR1,C5,NODAL,ISL1,CYP1B1,ARNT,NOX1,IL1A
GO:0046487	glyoxylate metabolic process	GO_GLYOXYLATE_METABOLIC_PROCESS	0.52584652700206	1.7817944531746	0.00323671939288653	0.0947373693604875	28	DLAT,NDUFAB1,DDO,AMT,DLD,LIPT2,OGDH,DHTKD1,PDHA1,LIAS,IDH2,PDHX,PDHB,IDH1,HOGA1,DBT,DLST
GO:0045732	positive regulation of protein catabolic process	GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS	0.288394627270985	1.44255403357293	0.00326606220142342	0.0947721152585451	244	RNF144B,CDC26,RNF40,FBXW7,OSBPL7,TRIB2,ATPIF1,PRICKLE1,CSNK2A1,VIP,PSMD11,PPP2R3A,EDEM2,LRRK2,PSMD2,PSMC6,NEDD4L,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,PCSK9,FZR1,GJA1,USP13,VPS11,BTRC,GSK3B,CAV3,PTEN,CDK5RAP3,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,DNAJB2,SGTA,RNF144A,RNF125,FOXO1,ANAPC11,TNF,ARIH2,PSMA8,CDKN1B,SOCS4,SOX17,CDK1,PSMD8,TRIM32,VCP,PSMB10,GGA3,APC,RHBDD3,TRIB3,SOX9,DLGAP5,RDX,PSMD3,PSMB1,BAG6,CSNK1A1,SMAD7,OAZ1,RHBDD1,SUMO2,PSMA5,SUMO1,PSMB9,USP5,NDUFA13,EGF,CHFR,ESPL1
GO:0034763	negative regulation of transmembrane transport	GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT	0.39123885078445	1.64463623605091	0.00340452415632733	0.0979455411128015	76	AGT,OPRL1,AKT2,DRD4,CALM3,APOC3,NEDD4L,ATP1A2,DRD2,PPIF,PCSK9,CAV3,PLN,KCNH2,SLC26A5,CALM1,HAMP,MTOR,KCNRG,SEMG1,GRK6,ANK3,SLC30A1,FGF12,TRDN,OAZ1,SUMO1,PRKCE,COMMD1
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL	0.311035695237836	1.49128498234309	0.00350853855235371	0.100082548874768	174	DCUN1D2,CDC26,RNF40,FBXW7,PRICKLE1,PSMD11,ADRB2,LRRK2,PIN1,RNF111,PSMD2,UBE2N,PSMC6,MAD2L1,RNF180,GOLGA2,PINK1,FZR1,HDAC4,BTRC,CAV3,PTEN,PELI1,CDK5RAP3,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,DNAJA3,DNAJB2,AIMP2,HAMP,ANAPC11,PSMA8,CDK1,PSMD8,VCP,PSMB10,PIAS3,TRIB3,MALT1,PSMD3,PSMB1,SMAD7,PSMA5,PSMB9,PIAS4,TSPYL5,CDC20B,MTA1,COMMD1,EGF,CHFR,RASSF1,PSMD6,PAXIP1,PSMB3,PSMB6,RASSF5,TICAM1,PSMD1,RNF20,SART3,PLK1,WFS1,UBE3A,CDKN2A,PSME2,PTK2,ARRDC4,UBE2D1,UBE2S
GO:0051056	regulation of small gtpase mediated signal transduction	GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	0.285367534850379	1.43666048539888	0.00358480816431986	0.100111467727377	257	MCF2L,RHOT2,AMOT,MADD,ARHGAP10,RAPGEF1,FLCN,DENND4B,OBSCN,ARHGAP26,PREX2,MFN2,DLC1,TIAM1,ARHGEF12,ALS2,SIPA1L2,FBXO8,FGD6,APOC3,ARFGEF2,RALGPS1,TSC2,ARHGEF2,ARAP1,STAMBP,CDH2,CYTH1,PLEKHG2,ABR,ARHGAP15,RASAL3,RHOV,MYO9B,PLCE1,RASGRF1,ARHGEF6,STARD13,RASGEF1A,RASAL1,ARHGAP35,SPATA13,AKAP13,TRIO,ITSN2,TRIP10,RAF1,RASAL2,RHOF,PSD3,ARHGAP22,OPHN1,FARP2,ARFGEF1,ARHGDIB,SYDE1,ARHGAP12,RHOBTB2,IQSEC1,RHOH,RDX,SCAI,ARHGAP25,KANK1,ARHGEF37,ARHGEF10L,GBF1,FGD5,MAPKAP1,ARHGEF9,BCL6,RALGPS2,ITPKB,FAM13B
GO:0022406	membrane docking	GO_MEMBRANE_DOCKING	-0.394164139142803	-1.66072541921675	0.00361609507796485	0.100111467727377	64	CFTR,STX19,EZR,SNAP25,PEX5L,SCFD1,EXOC5,STXBP3,RAB13,STX11,VPS33A,UNC13B,KCNB1,STX2,STXBP1,MSN,VPS18,VPS45,STX12,TSNARE1,PEX5,SYT1
GO:2000463	positive regulation of excitatory postsynaptic potential	GO_POSITIVE_REGULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL	0.573013303411546	1.80349362097092	0.00361737076204714	0.100111467727377	21	SHANK3,NLGN3,NRXN1,DLG4,DRD4,SHANK1,STX1A,GSK3B,PTEN,PRKCZ
GO:1901385	regulation of voltage gated calcium channel activity	GO_REGULATION_OF_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY	0.555792973492242	1.79201475154962	0.00365526615480695	0.100111467727377	23	OPRL1,DRD4,CALM3,CACNA2D1,S100A1,DRD2,DMD,CALM1,AHNAK
GO:0009100	glycoprotein metabolic process	GO_GLYCOPROTEIN_METABOLIC_PROCESS	-0.253802192759121	-1.37161767791981	0.00371737124871113	0.100111467727377	325	GAL3ST1,GCNT3,SLC34A1,MUC2,GALNT12,MUC7,LRP2,MUC16,SULF1,LIPC,ALG10B,SRD5A3,MUC5B,MAN1C1,B3GALT6,B3GNT6,BMP2,B3GNT5,POGLUT1,MGAT5B,MUC1,HS6ST3,DPY19L1,GALNTL5,PGM3,DAD1,GCNT1,RPN1,FUT10,ART5,EXTL2,MGAT3,SERP2,SPOCK2,FUT8,MUC6,FUT7,BMPR1B,SULF2,HPSE,B4GALT7,B4GALT2,SERP1,IDUA,ALG3,HIF1A,CHST8,NDST3,GALNT5,ERP44,ALG10,SGSH,DPY19L3,MAN1A1,GAL3ST4,TMEM115,DPAGT1,FKTN,ADAMTSL1,B4GALT5,EXT1,GALNT10,HS3ST5,UGGT2,DHDDS,GXYLT2,SIRT6,FBXO2,DCN,MGAT2,ST3GAL5,DOLPP1,THBS1,FUT1,PARP4,EXTL1,FUT2,MUC21,GALNT1,C1GALT1C1,ISPD,CHST3,STT3A,PORCN,B4GALT4,B3GAT1,SIRT1,OSTC,PSEN1,ALG1L,ASGR2,DSEL,LMAN1,CYTL1,MCFD2,ALG2,COL11A1,POMGNT1,ALG1,ADAMTS9,MUC12,ARF4,ALG12,HS3ST4,PHLDA1
GO:1903779	regulation of cardiac conduction	GO_REGULATION_OF_CARDIAC_CONDUCTION	0.413571445595434	1.66662973997976	0.00372188646473956	0.100111467727377	61	AGT,PRKACA,TRPM4,ANK2,ITPR1,DMPK,CALM3,RYR2,ATP1A2,HRC,RNF207,FXYD3,FXYD1,PLN,NPR2,SLC8A1,TNNI3,CALM1,TMEM65,GJA5,NKX2-5,ACE2,FXYD7,TRDN,ATP1A3,ATP2A2
GO:0052547	regulation of peptidase activity	GO_REGULATION_OF_PEPTIDASE_ACTIVITY	-0.246453513254178	-1.34971774765704	0.00374542226168017	0.100111467727377	369	VTN,WFDC8,SERPINA3,TIMP1,SLPI,C3,BBC3,CST2,C4A,LXN,P2RX1,PI3,SFN,DAP,SPINT1,SSPO,IFT57,SPINT2,AQP1,SERPINB8,SFRP2,WFDC10B,WFDC2,CTGF,TNFSF14,SPOCK1,WNT9A,SERPINH1,CST1,SPINT4,CYR61,CRIM1,SERPING1,MAPK12,CRB2,CYCS,SNCA,PCOLCE,KLF4,CSTB,SERPINA6,PCSK1N,ITIH6,STAT3,BOK,PYCARD,BCAP31,RIPK1,NLE1,PTTG3P,ACVR1C,SERPINA5,TRADD,SEMG2,EIF2AK3,PLAUR,CASP3,MAGEA3,RPS27L,RPS3,SORL1,PPARG,SERPINB2,COL7A1,S100A9,SH3RF1,DAPK1,RAG1,ARL6IP5,PROS1,FAS,PRELID1,HGF,C5,NLRP3,NLRP12,RPS6KA1,FABP1,TIMP2,THBS1,BAX,NOD1,ASPH,SPINK1,F2R,TRIAP1,NEK5,NODAL,MDM2,SENP1,MYC,CARD17,IFI16,IFI6,PCOLCE2,F3,SIRT1,PAWR,RET,FOXL2,TNFAIP8,TIMP4,SERPINF1,SERPINC1,CST4,WFDC5,MMP14
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS	0.479145556096505	1.73549441784176	0.00374748809674675	0.100111467727377	37	DDX3X,BAD,PIK3R1,KIAA0141,MOAP1,TNFRSF10D,BAG3,CASP10,DDX47,TNFRSF10B,CASP8AP2,TNF,DEDD,SORT1,FASLG,BID,TNFRSF18
GO:0007606	sensory perception of chemical stimulus	GO_SENSORY_PERCEPTION_OF_CHEMICAL_STIMULUS	0.253414177316603	1.35155863810907	0.0038493980522966	0.102024203496302	449	TAS2R42,OR1D2,OR4M1,OR1M1,OR2C1,OR51M1,OR6C6,TAS2R13,CNGA2,GNAS,OR5K3,OR5K4,PLCB2,OR10T2,OR2A2,OR1L3,OR8J1,OR5J2,OR52N1,OR52B2,OR2AE1,OR5B2,OR9Q2,OR52N2,OR11G2,OR51G1,OR13C5,OR5B12,OR52I2,OR5K1,OR51B5,OR1F2P,OR1N2,OR1D5,OR6S1,OR52E4,OR6C68,OR10A5,OR52B4,DRD2,OR5D18,OR11H6,OR10X1,TAS2R38,OR7A17,OR2L3,TAS2R4,OR13C9,OR11A1,OR2F2,TAS2R10,OR14I1,OR10H4,OR6K3,TAS2R20,OR8I2,OR4S1,OR51A4,OR11H4,OR4C6,OR2M2,OR7A10,OR11L1,OR13D1,OR8J3,OR5L1,OR5AN1,OR4D5,OR51S1,OR4C13,OR4X1,OR5AU1,TAS1R2,TAAR3,OR10A6,OR5M10,GNAT2,OR2Z1,OR2G6,OR2L2,OR4A15,OR2AG1,OR4F5,TAS2R31,OR7D4,OR2D3,OR5M11,OR4A47,BEST2,OR2AT4,OR4K15,PIP,OR4C46,OR52N4,OR52E2,OR4C16,PKD2L1,OR5B17,OR1L8,OR2T4,OR13C8,OR11H1,OR2F1,OR9A4,MKKS,OR8H2,TAS2R9,OR5F1,OR13G1,OR13C2,CD36,TAS2R19,OR10C1,OR51I1,UBR3,OR1J2,OR8H1,OR51D1,OR4A16,OR1B1,OR5P2,OR51F1
GO:0045685	regulation of glial cell differentiation	GO_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION	-0.409794665898612	-1.68012088413006	0.00391692475860813	0.103002880761523	56	DLX1,NKX6-1,SPINT1,SLC45A3,ID4,BMP4,BMP2,TNFRSF21,PRMT5,CLCF1,CTNNB1,TP73,IL6ST,F2,MAG,PPARG,RNF112
GO:0030258	lipid modification	GO_LIPID_MODIFICATION	0.303429047585089	1.47225661997107	0.00398656807768018	0.104021613561794	191	PIK3C2B,SLC25A17,DECR1,IVD,CYP4V2,PIK3R1,MTMR1,PPARD,ACOX3,PDGFB,AGK,ACAD9,ACADM,ACAD10,LCAT,SMG1,INPP5J,PIP5K1B,INPPL1,IMPA2,FGF1,PI4KB,PTEN,INPP5D,PIK3C3,INPP1,PIP4K2C,ADIPOR2,IRS1,PIKFYVE,PI4K2A,HADH,PIP4K2B,IP6K2,FGFR1,DGKZ,ECI2,ERBB4,ETFA,PIK3R5,PEX7,ADH7,PIK3C2G,ACOT8,CERK,HADHB,EFR3B,ECHS1,FAM126A,CD80,PLA2G7,GCDH,PIP5K1C,GAB1,FGF6,ACADVL,TTC7B,HADHA,FGF8,INPP5A,EGF,SACM1L,INPP5F,SCP2,TMEM150A,MTMR2,EFR3A,PIK3R6,PIK3R2,PIK3CB,CYGB,ACADSB,EREG
GO:0045778	positive regulation of ossification	GO_POSITIVE_REGULATION_OF_OSSIFICATION	-0.366744490518025	-1.61009531776356	0.0040755490346771	0.104752243738263	79	OSR1,PRKD1,ID4,BMP4,WNT5A,SFRP2,BMP2,NPNT,ANO6,CEBPB,CYR61,SOX11,TACR1,ACVR1,WNT10B,CTNNB1,BMPR1B,IL6ST,CEBPA,MSX2,WNT7B
GO:0046578	regulation of ras protein signal transduction	GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION	0.309879656080532	1.48346425227376	0.00407681043663472	0.104752243738263	172	MCF2L,MADD,RAPGEF1,FLCN,DENND4B,OBSCN,PREX2,MFN2,DLC1,TIAM1,ARHGEF12,ALS2,FBXO8,FGD6,APOC3,ARFGEF2,RALGPS1,ARHGEF2,STAMBP,CDH2,CYTH1,PLEKHG2,ABR,RASAL3,MYO9B,PLCE1,RASGRF1,ARHGEF6,RASGEF1A,RASAL1,ARHGAP35,SPATA13,AKAP13,TRIO,ITSN2,RAF1,RASAL2,PSD3,FARP2,ARFGEF1,ARHGDIB,IQSEC1,RDX,SCAI,KANK1,ARHGEF37,ARHGEF10L,GBF1,FGD5,MAPKAP1,ARHGEF9,BCL6,RALGPS2,ITPKB,ARF6
GO:1901888	regulation of cell junction assembly	GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.40240800874231	1.64856530142017	0.00415734493631864	0.106012295876125	66	AGT,RAPGEF1,PRKACA,GPM6B,CLASP1,DLC1,ROCK2,TSC1,MACF1,GJA1,RAPGEF2,PTEN,PRKCH,PKP2,EPHA3,DAPK3,IKBKB,TNF,TEK,ACE2,VEGFA,LDB1,SMAD3,LIMS1,BCAS3
GO:0098815	modulation of excitatory postsynaptic potential	GO_MODULATION_OF_EXCITATORY_POSTSYNAPTIC_POTENTIAL	0.508329818401988	1.7519478236322	0.00434124363861883	0.109869369079631	30	SHANK3,NLGN3,NRXN1,DLG4,DRD4,DMPK,LRRK2,SHANK1,STX1A,GSK3B,PTEN,PRKCZ,ZMYND8,NLGN4X,NLGN2,MTMR2
GO:0010466	negative regulation of peptidase activity	GO_NEGATIVE_REGULATION_OF_PEPTIDASE_ACTIVITY	-0.273600491367286	-1.41865593669993	0.00451279923230542	0.113358822507015	230	VTN,WFDC8,SERPINA3,TIMP1,SLPI,C3,CST2,C4A,LXN,PI3,SFN,SPINT1,SSPO,SPINT2,AQP1,SERPINB8,SFRP2,WFDC10B,WFDC2,TNFSF14,SPOCK1,WNT9A,SERPINH1,CST1,SPINT4,CRIM1,SERPING1,CRB2,SNCA,KLF4,CSTB,SERPINA6,PCSK1N,ITIH6,NLE1,PTTG3P,SERPINA5,PLAUR,MAGEA3,SORL1,SERPINB2,COL7A1,SH3RF1,RAG1,PROS1,HGF,C5,RPS6KA1,FABP1,TIMP2,THBS1,SPINK1,TRIAP1
GO:0006692	prostanoid metabolic process	GO_PROSTANOID_METABOLIC_PROCESS	-0.520773584302026	-1.78496125182352	0.00459714493104283	0.114622146947334	26	PDPN,PTGIS,TBXAS1,AKR1C3,TNFRSF1A,PLA2G4F,HPGD,PTGR1,PTGS1,MIF,EDN1
GO:0055001	muscle cell development	GO_MUSCLE_CELL_DEVELOPMENT	0.341455695229264	1.54738799493534	0.00463373083475298	0.114684838160136	118	XK,AGT,OBSCN,ANK2,DNER,LDB3,CFLAR,SGCD,SGCG,CACNA2D2,CAPN3,BMP10,LMOD1,LMOD3,CAV3,OBSL1,TCAP,DMD,PRKAR1A,SLC8A1,AGTR2,NFATC4,MYPN,TTN,TMOD1,MYL2,MTOR,NKX2-5,FLNC,FHL2,CDK1,VEGFA,HOMER1,FHOD3,MYLK3,HEY2,LRRC10,CFL2,ATP2A2,PROX1,TBX3,ADM,SRF,SGCB,PTCD2,P2RX2,CASQ2,ACTN2,SMO,MYOCD,NEBL
GO:0072079	nephron tubule formation	GO_NEPHRON_TUBULE_FORMATION	-0.584072810535731	-1.81381116752136	0.00472423881243905	0.116071444107079	18	WNT6,PAX8,OSR1,GATA3,CTNNB1,IRX1,GDNF,WNT9B,IRX2,NOG
GO:0006643	membrane lipid metabolic process	GO_MEMBRANE_LIPID_METABOLIC_PROCESS	-0.294485723071859	-1.46179528279485	0.00477082552766329	0.116366657435613	167	SMPDL3B,GAL3ST1,P2RX1,SMPD3,ALDH3B1,ARSF,DEGS2,ORMDL2,PRKD1,PIGV,ARSH,ITGB8,PIGW,B3GNT5,POGLUT1,SGPP2,PIGX,SMPDL3A,ALDH3A2,SMPD2,ALOX12B,SGPL1,PLAUR,GAL3ST2,ARSI,ARSD,GAL3ST4,PIGU,CERS2,SGMS2,NEU1,KDSR,SERINC2,SFTPB,NEU2,ALDH3B2,ST3GAL5,PIGZ,BAX,ARSK,CLN3,DEGS1,PIGF,SPNS2,KDELC2,ARSE,PIGQ,AGMO,B4GALT4,PIGK,UGT8
GO:0001655	urogenital system development	GO_UROGENITAL_SYSTEM_DEVELOPMENT	-0.259206343129428	-1.37931396541432	0.00484467750951633	0.116775192143467	284	GCNT3,C5orf42,ASS1,SLC34A1,WNT6,RBP4,TBX18,ITGA3,SULF1,PAX8,OSR1,TRAF3IP1,RARA,WT1,TMED10,RDH10,TGFBR1,ID4,SEC63,BMP4,WNT5A,BMP2,PKD1L3,PYGO1,NPNT,ANGPT1,GATA3,FGFR2,SDC1,FOXF1,FOXA1,SOX11,GCNT1,CRIP1,ANXA1,UMOD,AGTR1,ZNF354A,SIM1,POU3F3,SGPL1,CTNNB1,CAT,TP73,SULF2,NPHS1,DLG5,NLE1,WNT7B,ROBO2,RRM2B,ADIPOQ
GO:0043502	regulation of muscle adaptation	GO_REGULATION_OF_MUSCLE_ADAPTATION	0.412355903722533	1.65022827179178	0.00485695986336465	0.116775192143467	59	AGT,PDE5A,SCN5A,AKAP1,PIN1,BMP10,GTF2IRD1,HDAC4,MTMR4,GSK3B,AKAP6,CAV3,DDX39B,AKAP13,MYH7,SRL,CAMK2G,EP300,MTOR,CAMK2B
GO:0032232	negative regulation of actin filament bundle assembly	GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	0.591457306239976	1.7844217426298	0.00493900514324972	0.11790561214311	18	SHANK3,CLASP1,DLC1,SHANK1,ARAP1,PPP1R9A,S1PR1,PPFIA1,TMEFF2,TACSTD2,CLASP2
GO:0032330	regulation of chondrocyte differentiation	GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION	-0.440857176579395	-1.69866392119294	0.00504461683332586	0.119243138396737	42	GDF5,NKX3-2,EFEMP1,TGFBR1,BMP4,CTGF,WNT9A,CTNNB1,FGF18,BMPR1B,SOX6,PTHLH,SCIN
GO:0042330	taxis	GO_TAXIS	-0.238471019677906	-1.32327475545358	0.00506588496456727	0.119243138396737	423	SEMA3F,LHX9,SEMA3C,LHX4,IL16,SCG2,EZR,CCL3,CCL28,TNFSF11,CCL19,PIP5K1A,KIF5A,EFNB3,ARHGEF5,GBX1,FLRT3,BMP4,WNT5A,FMOD,MET,CCR6,GAP43,FGF7,ANO6,ANGPT1,KRAS,GATA3,UNC5D,NEO1,EFNA5,LPAR1,CYR61,RPS19,GBX2,SEMA3A,ANXA1,SEMA3B,FLRT2,UNC5A,AGTR1,OTX2,PLXNB2,SPTBN4,EVL,CMTM4,CXCL1,BMPR1B,S100A12,PLXNA2,PARVA,SLIT3,FEZF1,ISL2,CCL21,ARHGEF16,NR4A3,ROBO2,ARTN,EPYC,PLAUR,RAB13,SAA1,FZD3,IL17RC,USP33,SEMA3D,CDK5,C5AR1,NOV,S100A9,CDH4,RARRES2,EXT1,CMTM7,LMX1A,BOC,EDNRB,HGF,C5,CMKLR1,CMTM3,RHOG,SEMA3E,EPHA2,SPTBN2,HMGB2,PLP2,RALA,SEMA4B,NRCAM,ALKBH1,CCL4,RHOA,NTN4,SEMA4A,MIF,RNASE2,EDN1,PLXNA4,CCL18,POU4F2,SPTAN1,ISPD
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	GO_REGULATION_OF_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	-0.521375368995029	-1.76857031184184	0.00533936850431764	0.124807738788425	25	SULF1,WNT5A,GATA3,FGFR2,OTX2,CTNNB1,SULF2,FGFBP1,PRDM14,THBS1,FAM20C,FGFBP3,NOG,HHIP
GO:0006376	mrna splice site selection	GO_MRNA_SPLICE_SITE_SELECTION	0.544230329943818	1.75473391355073	0.00540024245986555	0.125055513835372	23	SF3A2,CELF1,PRPF39,LUC7L,SFSWAP,SETX,SRSF1,SNRPC,SF1
GO:0060271	cilium morphogenesis	GO_CILIUM_MORPHOGENESIS	-0.290173226489562	-1.45031965715633	0.0054242736244695	0.125055513835372	175	C5orf42,TRAF3IP1,IQCB1,C11orf63,IFT57,RFX4,WDR35,BBS7,SSX2IP,KIF3A,ACTR3,CCDC114,ATP6V0D1,PARVA,TTLL1,WDR19,SNX10,RFX2,B9D2,DNAH1,TTC30B,SPEF2,DZIP1L,DYNC2LI1,ONECUT1,CEP89,PCM1,TTC26,IFT52,C21orf2,DYNLL1,IFT20,CEP41,ARL13B,E2F4,IQUB,FBF1,CCDC13,TMEM231,RAB17,RP1L1,KIAA0586,TTC8,AKAP4,FAM161A,BBS10,DNAH5,RAB23,IFT88,C5orf30,LRRC6,ABCC4,DYNC2H1,CLUAP1,HSPB11,RSG1,IFT140,SEPT2,EHD3,KIF24
GO:0033044	regulation of chromosome organization	GO_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.280142977770399	1.40796947721734	0.00546916716557984	0.125232766526134	254	TET1,SMARCB1,PHF2,UHRF1,JARID2,PCID2,HMBOX1,FLCN,TRIP12,CDC26,RNF40,ZNF304,PAF1,CSNK2A1,AKAP8,SMG6,UBE2N,MCRS1,MAD2L1,MTHFR,GOLGA2,EED,NSD1,HMGA1,PTEN,OBFC1,MAP3K4,KDM5A,UCN,SETDB1,KAT2A,UBR5,ERCC1,GORASP1,TLK2,MAPKAPK5,EP300,TCP1,ERCC4,ACD,GFI1B,AICDA,ANAPC11,TERF2IP,SETD7,MAPK1,VEGFA,APC,CTCFL,DLGAP5,SFPQ,CCT3,SPI1,MAP1S,ATRX,BCOR,DMRTC2,WBP2,KLHL22,TPR,MAD1L1,BCL6,APOBEC1,MRE11A,MAPK8,ASF1A,UBE2B,ESPL1,CCT7,CHTOP,HDAC5,GATA2,AKAP8L,WRAP53,CCT4,PRKCQ,GCG,TWIST1,PKIB,PAXIP1,MAP2K7,RNF20,MYOCD,NSMCE2,SIN3A,SART3,CENPV,PLK1,PPARGC1A,RPS6KA5,USP44,HNRNPU,FOXP3,NEK7,TRIM28,RNF4,GFI1,ATM,ATAD2B,MAPK3,SETMAR,CCT8,OGT,PIWIL2,ATR,NAT10,MECP2,C6orf89,DHX36,TNKS,MTF2,CTCF
GO:0071875	adrenergic receptor signaling pathway	GO_ADRENERGIC_RECEPTOR_SIGNALING_PATHWAY	0.543727640795919	1.75311311873784	0.00551045148965872	0.1253255386094	23	GNAS,ADRB1,ADRB2,DRD2,ADRA2C,RAPGEF2,PLN,AKAP13,ADCY9
GO:0031935	regulation of chromatin silencing	GO_REGULATION_OF_CHROMATIN_SILENCING	0.569140260077714	1.76667113699876	0.00562546262028127	0.127082598522596	20	TET1,PHF2,UHRF1,ZNF304,HMGA1,SETDB1,AICDA,APOBEC1,ASF1A,SIN3A,TRIM28,ATAD2B
GO:0045861	negative regulation of proteolysis	GO_NEGATIVE_REGULATION_OF_PROTEOLYSIS	-0.253873071720635	-1.36059458998414	0.00566899516389038	0.1272122514777	303	VTN,WFDC8,SERPINA3,TIMP1,SLPI,C3,CD55,CST2,C4A,LXN,PI3,SFN,PTPN3,SPINT1,SSPO,SPINT2,AQP1,SERPINB8,C4BPA,SFRP2,WFDC10B,WFDC2,TNFSF14,GAS1,SPOCK1,WNT9A,SERPINH1,CST1,SPINT4,CRIM1,SERPING1,CRB2,SNCA,CHAC1,KLF4,CSTB,SERPINA6,PCSK1N,ITIH6,C4BPB,NLE1,PTTG3P,SERPINA5,F2,PLAUR,DNAJC1,MASP1,MAGEA3,CDK5,SORL1,SERPINB2,COL7A1,SH3RF1,RAG1,TEX14,PROS1,MTM1,HGF,C5,RPS6KA1,FABP1,TIMP2,THBS1,TMEM59,SPINK1,TRIAP1,PSMG2,CLN3,ZW10,MDM2,SENP1
GO:0032434	regulation of proteasomal ubiquitin dependent protein catabolic process	GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS	0.32373448281074	1.49920421566615	0.00571351296527942	0.127362149941262	136	GNA12,PCID2,RNF144B,UBQLN4,TRIB2,PRICKLE1,CSNK2A1,LRRK2,N4BP1,RAD23A,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,GSK3B,PTEN,GORASP1,TLK2,DNAJB2,SGTA,SHH,RNF144A,RNF125,ANAPC11,ARIH2,PARK7,SOCS4,VCP,APC,TRIB3,DLGAP5,PBK,BAG6,CSNK1A1,SMAD7,SUMO2,USP14,KLHL22,SUMO1,TPR,MAD1L1,USP5,UBXN1,COMMD1,CHFR,ESPL1
GO:0060969	negative regulation of gene silencing	GO_NEGATIVE_REGULATION_OF_GENE_SILENCING	0.597508118369678	1.77502433768261	0.00589570004463622	0.130558725988457	17	TET1,PHF2,ADAR,ESR1,HMGA1,AICDA,NCOR1,APOBEC1,ASF1A
GO:1901800	positive regulation of proteasomal protein catabolic process	GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS	0.357594201633782	1.5571111413961	0.00598511527852471	0.131672536127544	93	RNF144B,RNF40,FBXW7,OSBPL7,TRIB2,PRICKLE1,LRRK2,PSMC6,TAF1,RNF180,RNF14,GOLGA2,GSK3B,PTEN,PSMC5,GORASP1,DNAJB2,SGTA,RNF144A,RNF125,ANAPC11,ARIH2,SOCS4,VCP,TRIB3,DLGAP5,CSNK1A1,SMAD7,SUMO2,SUMO1,USP5,CHFR,ESPL1
GO:0018205	peptidyl lysine modification	GO_PEPTIDYL_LYSINE_MODIFICATION	0.275795516875036	1.39541207465769	0.0060354401042924	0.131917476565248	269	WDR82,TRIM16,HERC2,TRPM4,POM121,ATP7A,HDAC9,PRDM2,DYDC1,MEAF6,RANGAP1,NFATC2IP,CREBBP,MCRS1,KAT7,DR1,SUV39H1,NUP85,TAF1,NSD1,SP100,EYA1,RAE1,HDAC4,KAT8,WHSC1L1,SENP5,SIRT4,MED24,SIRT5,SETDB1,KAT6A,SMYD1,KAT2A,SMC1A,EZH2,EZH1,METTL21C,SAE1,CAMKMT,EP300,TET2,NUP188,METTL21A,ING3,INCENP,RBBP5,SETD7,SETD1B,MECOM,HDAC6,BRD1,ATF2,NAA50,NCOA3,LDB1,PIAS3,PRDM9,SETDB2,SPI1,MSL3P1,IVL,MITF,CRTC2,BAG6,NCOA1,SUMO2,SUMO1,TPR,JMJD6,BCL11A,AAAS,RNF168,SETD3,PIAS4,PCGF2,MTA1,UBE2I,POM121C,KAT6B,SCMH1,SUPT7L,ING5,HIST1H1D,CTH,BRCA2,PAXIP1,TOP2B,PLOD1,NUP214,WRN,PER1,NSMCE2,SIRT2,HCFC1,NUP35,TADA1,CDKN2A,USP22,SUPT3H,POR,TRIM28,NCOA2,IFIH1,CBX8,MSL2,SMYD2,RPA1,SETMAR,OGT,SETD6,NUP93,NAA60,PHF20,NAT8,TP53BP1
GO:0015985	energy coupled proton transport down electrochemical gradient	GO_ENERGY_COUPLED_PROTON_TRANSPORT_DOWN_ELECTROCHEMICAL_GRADIENT	0.564897392213892	1.75350082957385	0.00619911176905996	0.134539513425566	20	ATP5L,ATP5A1,ATP5G2,ATP5D,ATP5O,ATP5B,ATP5G3,ATP5F1,ATP5H,TCIRG1
GO:0002065	columnar cuboidal epithelial cell differentiation	GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION	-0.330545414389494	-1.52613562740724	0.00627924744532518	0.134539513425566	105	KLF5,NKX3-2,NKX6-1,RARA,PDZD7,BMP4,WNT5A,BMP2,LRTOMT,FGFR2,FOXA1,SOX11,NKX6-3,MEN1,ATP2B2,CDKN1A,GATA5,HIF1A,SPDEF,EMX1,BMP5,TYMS
GO:0090075	relaxation of muscle	GO_RELAXATION_OF_MUSCLE	0.57289663102653	1.75313089641015	0.00633755837224817	0.134539513425566	19	P2RY1,PDE5A,ATP1A2,KCNJ2,GUCY1A3,PLN,SLC8A1,SOD1,ADORA2B,ATP2A2,PRKG1
GO:0015807	l amino acid transport	GO_L_AMINO_ACID_TRANSPORT	-0.394779398249477	-1.62479942046816	0.00637261595885111	0.134539513425566	57	SLC1A6,SLC36A2,SLC1A1,SLC7A3,SLC6A17,SLC7A10,SLC17A7,SLC7A8,SLC7A2,PRAF2,SLC25A22,SLC1A4,SERINC2,ARL6IP5,SLC38A1,SLC7A4,SLC32A1,SLC7A9,SLC17A6,SLC6A9,PSEN1,SLC7A13,SLC7A11,SLC38A5,SLC7A14
GO:0010508	positive regulation of autophagy	GO_POSITIVE_REGULATION_OF_AUTOPHAGY	0.380135427629075	1.59035729895742	0.00640270179944064	0.134539513425566	74	LRSAM1,WDFY3,BAD,FLCN,ATG14,TP53INP2,ADRB2,ULK1,LRRK2,CALCOCO2,TPCN1,RAB12,PINK1,PRKAA2,RAB3GAP1,PIP4K2C,TRIM13,PIP4K2B,SCOC,MEFV,FOXO1,RNF152,PARK7
GO:0086065	cell communication involved in cardiac conduction	GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION	0.476481951636969	1.69152870802228	0.00642098370197905	0.134539513425566	34	PRKACA,ANK2,CTNNA3,SCN5A,RYR2,ATP1A2,RNF207,GJA1,PKP2,SLC8A1,CACNA1C,GJA5,KCNA5,GJC1,ATP1A3,ATP1B2,JUP,DSP,CASQ2
GO:0016441	posttranscriptional gene silencing	GO_POSTTRANSCRIPTIONAL_GENE_SILENCING	0.472772342483803	1.68919459164953	0.00643519360116343	0.134539513425566	35	ADAR,METTL3,WTIP,TNRC6C,ZCCHC11,SMAD1,TNRC6A,CELF1,CLP1,LIN28B,TNRC6B,SRRT,HNRNPA2B1,LIMD1,MOV10,DICER1,CNOT8,SMAD3
GO:0031016	pancreas development	GO_PANCREAS_DEVELOPMENT	-0.373156244461304	-1.59091464262154	0.00664182731248988	0.137846480888626	68	MSLN,NKX3-2,NKX6-1,BMP4,WNT5A,ILDR2,PAX4,FOXF1,ANXA1,XBP1,MEN1,CTNNB1,EIF2AK3,BMP5,SMAD2,ZIC3,ONECUT1,PDPK1,ACVR2B,RFX8,INSM1,AFP
GO:0061037	negative regulation of cartilage development	GO_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT	-0.536745136686466	-1.75969272522396	0.00667527521831433	0.137846480888626	22	GDF5,NKX3-2,RARA,EFEMP1,TGFBR1,BMP4,WNT9A,CTNNB1,LEP,PTHLH
GO:0072089	stem cell proliferation	GO_STEM_CELL_PROLIFERATION	-0.392967477165953	-1.61734207000991	0.00682780281305476	0.139165929041388	57	OSR1,ID4,BMP4,WNT5A,SFRP2,BMP2,FGF7,WNT2B,FGFR2,PLXNB2,WNT10B,CTNNB1,DAGLA,WNT7B,ARTN,FGF4,RAB10,FGF13,KCNA1,CD34,DOCK7,NKAP
GO:0010043	response to zinc ion	GO_RESPONSE_TO_ZINC_ION	-0.402638749428788	-1.63213872069681	0.0068346957311535	0.139165929041388	53	ASS1,MT1M,KHK,ALDOB,MT1E,MT2A,TSPO,CRIP1,MT1A,SLC30A2,MT1F,CPS1,ZACN,SLC18A2,MT1G,KRT14,HMBS,SLC30A8
GO:0098657	import into cell	GO_IMPORT_INTO_CELL	-0.458213338599946	-1.70316358655403	0.00686320386835127	0.139165929041388	36	STEAP3,STEAP1,SNAP25,SLC2A5,SNCA,SLC18A1,SLC22A3,SLC7A2,SLC6A3,SLC31A1,SLC38A1,SLC8A3,STEAP1B,PAWR,ATP1B1,ATP1A1,STEAP4
GO:0051591	response to camp	GO_RESPONSE_TO_CAMP	-0.335839648855029	-1.52907823922396	0.00706663504861276	0.141980521379935	97	ASS1,CFTR,EZR,FOXM1,WT1,ALDOB,AQP1,AREG,PAX4,DUOX2,GPD1,LDHA,SDC1,AQP8,PKLR,WNT10B,SLC6A3,STAR,CPS1,ADIPOQ,SPARC,RAPGEF3,ITPR3,AGXT,INPP5K,SLC8A3,ATP7B,AKAP7,JUNB,HNF4A,AQP9,HCN2,MMP19,THBD,ALDH3A1,JUN,RAP1A,DUSP1,PTK2B
GO:0042481	regulation of odontogenesis	GO_REGULATION_OF_ODONTOGENESIS	-0.520530555962371	-1.7475280407895	0.00710588648127029	0.141980521379935	24	WNT6,SP6,BMP4,BMP2,TNFRSF11B,CSF1,MMP20,PAX9,RSPO2,CD34,EDN1
GO:0007020	microtubule nucleation	GO_MICROTUBULE_NUCLEATION	0.579799564422551	1.74925043313796	0.00712999238724771	0.141980521379935	18	NDE1,TUBGCP5,CLASP1,TUBGCP2,GOLGA2,TUBG1,TUBGCP6,TUBGCP3,CLASP2
GO:0006415	translational termination	GO_TRANSLATIONAL_TERMINATION	0.36039411071279	1.55141587320725	0.00724713424619351	0.141980521379935	87	PTCD3,AURKAIP1,MRPL4,MRPL16,MRPL41,MRPL14,MRPL19,MRPS15,APEH,MRPL53,MRPL15,MRPL27,MRPS28,MRPL24,MRPL35,MRPL20,MRPL17,MRPL12,MRPL37,MRPL51,MRPS22,MRPS18B,MRPL39,MRPS25,MRPL46,GSPT1,MRPL18,MRPS30,MRRF,MRPS17,MRPL28,MRPL30,MRPS7,MRPL54,MRPS26,MRPL10,MRPL52,ETF1,MRPS9,MRPS18A,MRPS31,N6AMT1,MRPL36,MRPL1,DAP3
GO:0045137	development of primary sexual characteristics	GO_DEVELOPMENT_OF_PRIMARY_SEXUAL_CHARACTERISTICS	-0.277178910421377	-1.4078248456144	0.00725336038549328	0.141980521379935	196	LHX9,KIF18A,AMHR2,OSR1,IRX5,RARA,WT1,RDH10,TGFBR1,BMP4,WNT5A,SFRP2,NUPR1,FGF7,WNT2B,MGST1,CBX2,GATA3,DMRT1,CEBPB,FSHR,SDC1,ADAM15,UTF1,FANCF,INSL3,SGPL1,REC8,BMPR1B,BOK,SLIT3,AKR1C3,WDR19,STAR,ROBO2,RAB13,LEP,COL9A3,FGF9,FAS,MEA1,PRKACG,SOX15,ADCYAP1,BAX,HMGB2,HSD17B10,ACVR1B,AHR,TMF1,BASP1,AFP,FSHB,GPR149,FOXO3,INHBA,SIRT1,ARID4A,LRRC6,FOXL2,MMP19,MMP14,BCL2,PLA2G4A,NRIP1,FNDC3A,GATA6,TLR3,KLHL10,MAMLD1
GO:0051298	centrosome duplication	GO_CENTROSOME_DUPLICATION	0.488413795270516	1.69683602643902	0.00725509497247439	0.141980521379935	31	BRSK1,CEP192,NDE1,TUBGCP5,WDR62,ROCK2,C2CD3,TUBGCP2
GO:0000245	spliceosomal complex assembly	GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY	0.423903490491541	1.62559622226127	0.00780435173529941	0.151180692404156	48	SF3A2,PRPF6,SNRNP200,CELF1,SCAF11,DDX39B,PRPF39,LUC7L,SFSWAP,SETX,LSM4,SMN1,SRSF1,SNRPC,PRPF19,SF1,RBM5,DDX23
GO:0036498	ire1 mediated unfolded protein response	GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE	-0.406745698878687	-1.6290260085568	0.00783295711060948	0.151180692404156	50	KDELR3,SEC63,CUL7,PDIA6,SEC61G,DDX11,SSR1,XBP1,ATP6V0D1,SERP1,PDIA5,DNAJC3,HDGF,DNAJB9,SEC61A1,SEC31A,ZBTB17,ASNA1
GO:0036003	positive regulation of transcription from rna polymerase ii promoter in response to stress	GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_STRESS	-0.531174091839121	-1.74142832668597	0.00790089952069335	0.151180692404156	22	CEBPB,MUC1,CREB3L1,ATF3,XBP1,HIF1A,ATF6,MBTPS2,CREB3L3,NFE2L2
GO:0002067	glandular epithelial cell differentiation	GO_GLANDULAR_EPITHELIAL_CELL_DIFFERENTIATION	-0.443701981073811	-1.66896941952244	0.00790487280544608	0.151180692404156	38	NKX6-1,RARA,BMP4,WNT5A,BMP2,FGFR2,FOXA1,NKX6-3,MEN1,SPDEF,BMP5
GO:0010639	negative regulation of organelle organization	GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION	0.257147894628225	1.33969729035384	0.00795805930088371	0.151338009077822	352	TET1,SMARCB1,PHF2,SHANK3,CEP192,SPTB,JARID2,SPAG5,PARL,TUBGCP5,WDR62,AURKAIP1,FLCN,TRIP12,BIRC8,UBQLN4,NPM1,MAP1A,CLASP1,TBCD,DLC1,CSNK2A1,SMG6,LRRK2,SBDS,SHANK1,MCRS1,TUBGCP2,ARHGEF2,ARAP1,MAD2L1,PPIF,GOLGA2,LMOD1,LMOD3,PINK1,INPP5J,HMGA1,OSM,DYNC1H1,ADD1,CAV3,SIAH3,SIRT4,KDM5A,UCN,PRKAR1A,PPP1R9A,GPSM2,UBR5,ERCC1,SMC1A,TBC1D4,LIG3,MAP4,CAPZB,ERCC4,NME6,TMOD1,ACD,INSIG1,AICDA,KIFC1,TERF2IP,S1PR1,TUBG1,RGS14,NCOR1,HDAC6,PPFIA1,BAG4,ARFGEF1,APC,FHOD3,SPI1,TUBGCP6,RDX,ATRX,MKKS,BCOR,KANK1,FXN,KLHL22,GAS2L2,TPR,HAUS8,MAD1L1,APOBEC1,TUBGCP3,OPA1,CKAP5,ASF1A,PFN2,TOM1L2,UBE2B,UVRAG,TMEFF2,TBC1D30
GO:0043467	regulation of generation of precursor metabolites and energy	GO_REGULATION_OF_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY	0.364921654123219	1.55444363432549	0.00807904170674128	0.151456036188861	82	TRAP1,PRKACA,AKT2,ATP7A,PPARA,GRB10,APOC3,PGAM1,OPRK1,PPIF,PINK1,HDAC4,GSK3B,PRKAA2,IRS1,GCK,PPP1R3B,PPP1R3F,MTOR,PARK7,NCOR1,VCP,P2RX7,PPP1CB,HMGB1,PPP1R3E,PASK,PTH,PHKG2,DDIT4,CBFA2T3,PRKAG1,EPM2AIP1,SORBS1,BNIP3,NOS2,PPARGC1A
GO:0050891	multicellular organismal water homeostasis	GO_MULTICELLULAR_ORGANISMAL_WATER_HOMEOSTASIS	-0.393237039094028	-1.60674511265132	0.00809790273417952	0.151456036188861	55	CLDN1,SCNN1A,SFN,CYP26B1,AQP1,MYO5B,HRNR,AQP3,FLG,ALOX12B,TMEM79,PRKAR2B,SCNN1G,PRKAR1B,SCNN1B,ADCY2,PRKACG,CYP4F2,KRT16
GO:0043414	macromolecule methylation	GO_MACROMOLECULE_METHYLATION	0.299812073780394	1.43629913517289	0.00809925327213158	0.151456036188861	173	WDR82,GNAS,METTL3,NSUN2,ALKBH8,RAB6A,PRDM2,PRMT7,TDRD5,DYDC1,TARBP1,PCMTD2,SUV39H1,TRMT2B,EED,NSD1,KIAA1429,WHSC1L1,HENMT1,PCMTD1,METTL1,SETDB1,ZFP57,FBXO11,SMYD1,EZH2,METTL2B,EZH1,METTL21C,CAMKMT,TET2,METTL21A,TRMT1L,RBBP5,SETD7,SETD1B,MECOM,FTSJ3,CTCFL,PLD6,TDRKH,TRMT1,TFB2M,PRDM9,SETDB2,ATRX,BAZ2A,EMG1,METTL16,SETD3,SATB1,GSPT1,NSUN4,GATAD2B
GO:1903364	positive regulation of cellular protein catabolic process	GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS	0.297384060887021	1.43233626230063	0.00819142056477689	0.152333268624525	180	RNF144B,CDC26,RNF40,FBXW7,OSBPL7,TRIB2,ATPIF1,PRICKLE1,PSMD11,LRRK2,PSMD2,PSMC6,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,PCSK9,FZR1,VPS11,BTRC,GSK3B,CAV3,PTEN,CDK5RAP3,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,DNAJB2,SGTA,RNF144A,RNF125,ANAPC11,ARIH2,PSMA8,SOCS4,CDK1,PSMD8,VCP,PSMB10,TRIB3,DLGAP5,RDX,PSMD3,PSMB1,CSNK1A1,SMAD7,SUMO2,PSMA5,SUMO1,PSMB9,USP5,EGF,CHFR,ESPL1
GO:0006490	oligosaccharide lipid intermediate biosynthetic process	GO_OLIGOSACCHARIDE_LIPID_INTERMEDIATE_BIOSYNTHETIC_PROCESS	-0.545314474943583	-1.7425865420055	0.00835472781863278	0.154516559546802	20	ALG10B,SRD5A3,ALG14,ALG3,ALG10,DPAGT1,DHDDS,DOLPP1,MPDU1,ALG2,ALG1,ALG12,DOLK
GO:0031343	positive regulation of cell killing	GO_POSITIVE_REGULATION_OF_CELL_KILLING	0.469063961768741	1.6651945671911	0.00845823632130384	0.155576084467261	34	BAD,STAT5B,CRTAM,XCL1,HLA-B,CCR2,P2RX7,SH2D1A,IL21,AP1G1,NOS2,HLA-E,IL12RB1,STX7,RASGRP1
GO:0007098	centrosome cycle	GO_CENTROSOME_CYCLE	0.434922888792311	1.62923875171651	0.00853669518235029	0.156165847737995	43	BRSK1,CEP192,NDE1,TUBGCP5,WDR62,NPM1,TUBE1,ROCK2,C2CD3,TUBGCP2
GO:0099536	synaptic signaling	GO_SYNAPTIC_SIGNALING	-0.235118145194953	-1.29854965671131	0.00869025450031037	0.158115657556998	401	SLC1A6,DLGAP1,PTPRF,STX19,HAP1,P2RX1,SYT4,SSTR3,GPR176,DRD5,KIF5A,SNAP25,GRIA4,NLGN1,AGRN,ANXA9,KCNMB2,PCDHB10,SSTR4,SYN1,PCDHB5,SSTR2,SYTL1,GRIA2,SNAP91,SLC1A1,SYT17,GABBR2,BSN,TRIM9,NPY2R,GABRA4,PLCB3,TSPO,SNCA,OPRM1,LRFN4,TACR1,RPH3A,HTR3A,PDZD11,CTNNB1,C2CD4D,DLGAP2,HCRTR2,GRIN2A,SYN3,SLC17A7,HTR1F,NPFFR2,SLC6A3,CACNB1,SNAP23,CLSTN3,PCLO,HTR1B,RGS8,ZACN,HRH4,STX11,GLRA4,SYT6,CHRNB2,SLC18A2,CDK5,KCNN1,SLC1A4,NPBWR1,GRID2,UNC13B,LIN7B,NQO1,CDH8,SST,CHRNG,PCDHB16,SEZ6,OPRD1,CHRM4,CPNE6,MYCBPAP,RTN3,KCNA1,SYT5,STX2,STXBP1,GRIN2D,GRIN3B,GRIK2,CACNB4,LRFN3,CARTPT,CASK,SLC32A1,HCRT,GPR149,SHC3,GJD2,SLITRK5,SYTL5,KCNQ5,SNAPIN,RIT2,GABRA6,DLG1,GRM2,SLC6A9
GO:0045649	regulation of macrophage differentiation	GO_REGULATION_OF_MACROPHAGE_DIFFERENTIATION	-0.551429144034445	-1.73675588730973	0.00879708067248794	0.158371144943225	19	PRKCA,PTPN2,RIPK1,CSF1,ADIPOQ,TRIB1,INHBA,PF4
GO:0050764	regulation of phagocytosis	GO_REGULATION_OF_PHAGOCYTOSIS	-0.372122555638018	-1.56785797042805	0.00879839694129028	0.158371144943225	64	C3,C4A,C2,C4BPA,ANO6,ALOX15,LMAN2,CALR,PRTN3,C4BPB,PYCARD,TULP1,ADIPOQ,ABCA7,PPARG,PROS1,MBL2
GO:0060998	regulation of dendritic spine development	GO_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT	0.413035720053357	1.6114226595404	0.00895175006713813	0.16027441875525	52	CPEB3,SHANK3,NLGN3,HDAC2,PAFAH1B1,TIAM1,LRRK2,SHANK1,ARF1,PTEN,CFL1,PPP1R9A,DNM3,MTOR,CAMK2B,EPHA4,ZMYND8,IL2,SDK1,BHLHB9,ARF6,MARCKS,ITPKA,MEF2C
GO:0060351	cartilage development involved in endochondral bone morphogenesis	GO_CARTILAGE_DEVELOPMENT_INVOLVED_IN_ENDOCHONDRAL_BONE_MORPHOGENESIS	-0.550697640904499	-1.73445197867294	0.00905773491463574	0.160916621246878	19	MATN1,RARA,THBS3,SERPINH1,COMP
GO:0044057	regulation of system process	GO_REGULATION_OF_SYSTEM_PROCESS	0.243017850282059	1.30127564313161	0.0091202126521945	0.160916621246878	469	P2RY1,AGT,NLGN3,GNAS,PRKACA,PTPRM,PPARD,PDE5A,TRPM4,CACNA2D4,OPRL1,PDGFB,EPAS1,HSPB7,ANK2,ADRB1,TBX2,ITPR1,CTNNA3,VIP,NPY1R,FLT1,ADRB2,DMPK,SCN5A,P2RY2,CALM3,CACNA2D1,PPP1R12B,AKAP1,PIN1,CELF2,HRH2,ANXA6,RYR2,S100A1,CACNA2D2,WNK1,MYBPC3,ATP1A2,DRD2,HRC,OPRK1,RNF207,KCNJ2,BMP10,GHSR,ADRA2C,GTF2IRD1,FXYD3,NKX3-1,TACR3,GJA1,GLP1R,HMGCR,GUCY1A3,HDAC4,CACNG1,PLCE1,MTMR4,GSK3B,AKAP6,JAK2,CAV3,PTEN,DMD,UCN,PKP2,FXYD1,PLN,NPR2,DOCK4,DDX39B,SLC8A1,MTG1,AKAP13,MGLL,AGTR2,KCNH2,TNNI3,MYH7,CX3CL1,CALM1,TMEM65,SRL,CAMK2G,MYL9,FGFR1,EP300,ADA,CACNA1C,MYL2,ESR2,GJA5,HAMP,MTOR,DAPK3,KCNA5,NKX2-5,ACE2,CAMK2B,GDF9,CACNA1B,CYBA,SOD1,MYBPH,DICER1,TNNT2,KCNIP2,HEY2,CHRM2,TNNC2,NMUR2,ADORA2B,DES,CRHBP,PTAFR,IL2,FXYD7,CD38,GJC1,GNAO1,FTO,SMAD7,FAM19A4,TRDN,GALR1,ATP1A3,SUMO1,ATP2A2,NPFF,TNNT3,PRKG1,SNTA1,SCPEP1,NLGN2,ABCC9,KCND3,EMP2,TH,TRIM63,MYL4,ADM,PRKCQ,ATP1B2,APOA5,MTMR2,SRF,JUP
GO:0071384	cellular response to corticosteroid stimulus	GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS	-0.389899348665271	-1.59310749144375	0.00923524862381147	0.160916621246878	55	ASS1,SSTR3,AQP1,SSTR4,SSTR2,SGK1,ANXA1,ACVR1,ERRFI1,AKR1C3,STAR,UBE2L3,MSTN,HMBS,MYOD1,ADCYAP1,FLT3,AHR,EDN1,ATP2B1,SERPINF1,NTS,ISL1,SSTR5,RAN
GO:0032881	regulation of polysaccharide metabolic process	GO_REGULATION_OF_POLYSACCHARIDE_METABOLIC_PROCESS	0.442851098026645	1.63173368592716	0.00930409018644313	0.160916621246878	40	AKT2,PDGFB,GRB10,GSK3B,IRS1,GCK,PPP1R3B,PPP1R3F,MTOR,PPP1CB,NFKB1,HMGB1,PPP1R3E,PASK,PTH,EGF,PHKG2,EPM2AIP1,SORBS1
GO:0042060	wound healing	GO_WOUND_HEALING	-0.230924238887984	-1.28396151865423	0.00930684024209204	0.160916621246878	432	PDPN,PAX7,TIMP1,PRKCA,C3,TYRO3,P2RX1,DRD5,KDM1A,TRIM72,TGFBR1,DGKB,BMP4,WNT5A,PROCR,AHNAK2,CD177,GAP43,ENTPD2,HBE1,FGF7,ANO6,GATA3,PTK7,TREML1,ALOX15,SDC1,ADAM15,CYR61,ANXA5,SERPING1,DOCK11,OPRM1,ANXA1,FUT10,SPRR3,MMRN1,PRTN3,ACTG1,ARHGEF19,PAPSS2,WNT10B,C4BPB,F7,TOR1A,MMP12,NLRP6,IGFBP1,MIA3,SH2B1,HPSE,STXBP3,IFNA14,GATA5,MSX2,HIF1A,SERPINA5,F2,PLAUR,MSTN,SAA1,PRKAR2B,MYOF,CASP3,CDH3,CCNB1,TM4SF4,NOV,SERPINB2,TPM1,CYP4F11,SPARC,F13B,PRKAR1B,ITPR3,IL24,PROS1,LAT,SCNN1B,PRKACG,CYP4F2,IFNA16,HIST1H3C,F5,CD34,STXBP1,RHOG,DCN,RAP2B,MYOD1,SOX15,CAPZA1,VKORC1,KLF6,F2RL3,PDPK1,NFE2,F2R,TXK,DGKA,LOX,RHOA,GNA13,PDGFD,VPS45,RAD51B,C1GALT1C1,CDC42,PTPN12,CLIC1,HNF4A,F3,EYS,EHD2,CLEC1B,HIST1H3I,PF4,SERPINC1,NRG1,FGF2,PDCD10,LMAN1,THBD,F13A1,SLC7A11,WNT7A,RAC1,RHOC,ACTN1,DDR1,NOG,BLOC1S3
GO:0051100	negative regulation of binding	GO_NEGATIVE_REGULATION_OF_BINDING	0.324112311181189	1.48101858878466	0.00942595108695652	0.160916621246878	124	TFIP11,P2RY1,TMC8,CYP2D6,PDGFB,HABP4,ZNF304,HDAC2,ADRB2,PPARA,LRRK2,PIN1,HAND2,NFIB,GOLGA2,SP100,NKX3-1,PEX14,GSK3B,JAK2,IFIT2,LRPAP1,PLN,AES,FBXO18,NFATC4,GTPBP4,LHX2,IFIT1
GO:0030513	positive regulation of bmp signaling pathway	GO_POSITIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY	-0.46499568109877	-1.67921297319297	0.00944756159765807	0.160916621246878	32	GDF5,SULF1,BMP4,NEO1,CYR61,SOX11,CRB2,MSX2,SMAD2
NA	cellular protein complex assembly	GO_CELLULAR_PROTEIN_COMPLEX_ASSEMBLY	0.265904955404912	1.35862471431172	0.00946331966232067	0.160916621246878	292	COX15,NDUFA10,NDE1,TUBGCP5,ADRM1,DNAI2,POGZ,NDUFS2,C9orf24,CSNK2B,CLASP1,MSRB2,KIF13A,ACAD9,TBCD,BBS12,SCO1,NDUFAB1,NDUFA7,CENPA,NDUFB4,TAZ,PSMD11,ADRB2,RANBP6,NDUFB11,NDUFV1,ZMYND10,NDUFV2,TUBGCP2,OXA1L,FOXRED1,NDUFC1,SMAD1,COX18,NDUFB9,GOLGA2,THEG,HSPD1,NDUFB7,NDUFS6,JAK2,ATPAF1,TCAP,DMD,COX10,CADPS,NDUFAF4,NDUFB10,TTN,KIAA0368,TIMMDC1,PXN,BCS1L,IMMP1L,TCP1,STX4,NDUFS1,COX11,LONP1
GO:0055008	cardiac muscle tissue morphogenesis	GO_CARDIAC_MUSCLE_TISSUE_MORPHOGENESIS	0.415295194271677	1.60642984934756	0.00947901332088614	0.160916621246878	50	UBE4B,RYR2,MYBPC3,BMP10,XIRP2,TCAP,PKP2,TTN,TNNI3,MYH7,EGLN1,DLL4,MYL2,TBX20,S1PR1,NKX2-5,RXRA,TNNT2,HEY2,SMAD7,PROX1,MED1,DSP,PTCD2,TGFBR3
GO:0045773	positive regulation of axon extension	GO_POSITIVE_REGULATION_OF_AXON_EXTENSION	0.465782059022457	1.65354368997905	0.00949505238649593	0.160916621246878	34	CDKL5,NRP1,PAFAH1B1,TRPV2,MEGF8,MACF1,GSK3B,GOLGA4,LIMK1,EP300,SEMA5A,VEGFA,L1CAM,NTRK3,SRF
GO:0036342	post anal tail morphogenesis	GO_POST_ANAL_TAIL_MORPHOGENESIS	-0.559464978092443	-1.73739267912573	0.00951349008559974	0.160916621246878	18	TRAF3IP1,WNT5A,SFRP2,T,TMED2,FZD3,EPHA2
GO:0033275	actin myosin filament sliding	GO_ACTIN_MYOSIN_FILAMENT_SLIDING	0.453780170209946	1.64361944362482	0.00972174448286475	0.1633738759025	37	MYBPC3,MYL1,TCAP,DMD,TTN,TNNI3,MYH7,TPM2,TMOD1,MYL2,TNNT2,TNNC2,DES,TNNT3,MYH8,MYL4,TNNT1,ACTN2
GO:0018022	peptidyl lysine methylation	GO_PEPTIDYL_LYSINE_METHYLATION	0.393929154305439	1.58142543793497	0.00975583750932935	0.1633738759025	60	WDR82,PRDM2,DYDC1,SUV39H1,NSD1,WHSC1L1,SETDB1,SMYD1,EZH2,EZH1,METTL21C,CAMKMT,TET2,METTL21A,RBBP5,SETD7,SETD1B,MECOM,PRDM9,SETDB2
GO:2001251	negative regulation of chromosome organization	GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.351981022387655	1.51836317644053	0.00988978461859906	0.164371340953443	88	TET1,SMARCB1,PHF2,JARID2,TRIP12,CSNK2A1,SMG6,MCRS1,MAD2L1,HMGA1,KDM5A,UCN,UBR5,ERCC1,ERCC4,ACD,AICDA,TERF2IP,APC,SPI1,ATRX,BCOR,KLHL22,TPR,MAD1L1,APOBEC1,ASF1A,UBE2B,ESPL1
GO:0016055	wnt signaling pathway	GO_WNT_SIGNALING_PATHWAY	0.259953015039358	1.34081580722668	0.0099234701978343	0.164371340953443	320	LRP5,MARK2,PLCB2,DDX3X,PROP1,CSNK2B,CXXC4,PAF1,STRN,TNIK,PRICKLE1,TMEM88,CSNK2A1,LRP6,DVL2,PSMD11,DIXDC1,TIAM1,PPP2R3A,TNRC6C,LRRK2,CALM3,CAMK2A,GNG2,MARK1,CCND1,PSMD2,RYR2,PSMC6,FBXW4,BCL9L,ZRANB1,DRD2,MACF1,TNRC6A,PRICKLE2,BTRC,WIF1,GSK3B,PTEN,PRKAA2,DKK3,CHD8,AES,RGS20,FZD10,LRRFIP2,PSMC5,TCF7L1,PSMB7,MED12,PSME4,SHH,CALM1,WNT8B,AMOTL1,PPP3R1,TNRC6B,GNAT2,NKX2-5,ZNRF3,CTNNBIP1,PSMA8,FZD6,SOX17,DKK4,GRK6,PSMD8,AP2M1,PSMB10,APC,MOV10,LDB1
GO:0055003	cardiac myofibril assembly	GO_CARDIAC_MYOFIBRIL_ASSEMBLY	0.588217048639698	1.71873199632876	0.00996189945172382	0.164371340953443	16	OBSL1,TCAP,TTN,MYL2,NKX2-5,FHOD3,MYLK3,PROX1,SRF,NEBL,CSRP3,PDGFRA
GO:0070085	glycosylation	GO_GLYCOSYLATION	-0.260275835589865	-1.35800796724931	0.0102157525344424	0.167595710064696	241	GAL3ST1,GCNT3,MUC2,GALNT12,MUC7,LRP2,MUC16,ALG10B,SRD5A3,MUC5B,PIGV,MAN1C1,B3GALT6,B3GNT6,B3GNT5,POGLUT1,MGAT5B,MUC1,DPY19L1,GALNTL5,PGM3,DAD1,GCNT1,RPN1,FUT10,ART5,MGAT3,SERP2,FUT8,MUC6,FUT7,B4GALT7,B4GALT2,SERP1,ALG3,GALNT5,ALG10,DPY19L3,MAN1A1,TMEM115,DPAGT1,FKTN,ADAMTSL1,B4GALT5,EXT1,GALNT10,UGGT2,DHDDS,GXYLT2,SIRT6,MGAT2,ST3GAL5,DOLPP1,PIGZ,THBS1,FUT1,PARP4,EXTL1,FUT2,MUC21,GALNT1,C1GALT1C1,ISPD,STT3A,B4GALT4,B3GAT1,SIRT1,OSTC,PSEN1,ALG1L
GO:0051291	protein heterooligomerization	GO_PROTEIN_HETEROOLIGOMERIZATION	-0.326199628807732	-1.49063925135368	0.0102568972885702	0.167595710064696	99	CLDN1,P2RX1,NLGN1,S100A10,HBE1,COL6A2,C1QTNF1,HIST1H4C,SKIL,ANXA2,CNGA4,CTNNB1,RIPK1,STXBP3,TRADD,SEMG2,RIPK3,ADIPOQ,CHRNB2,HIST1H4D,MAGI2,ITPR3,HIST1H4E,HIST1H3C
GO:0016331	morphogenesis of embryonic epithelium	GO_MORPHOGENESIS_OF_EMBRYONIC_EPITHELIUM	-0.301744517921342	-1.44201611465456	0.0103309317376969	0.167989933473854	130	WNT6,PAX8,OSR1,RARA,SPINT1,RDH10,IFT57,BMP4,WNT5A,SFRP2,T,GATA3,PTK7,GRHL2,FGFR2,TMED2,SOX11,MTHFD1L,PLXNB2,COBL,CTNNB1,WNT7B,HIF1A,ST14,FZD3,STK3,IRX1,GDNF,IFT52,RALA,WNT9B,TULP3,SALL4,NODAL,LMO4,STIL
GO:0031960	response to corticosteroid	GO_RESPONSE_TO_CORTICOSTEROID	-0.281693844198475	-1.4018483150672	0.0103921470426203	0.168172918007019	170	ASS1,C3,APOA2,SSTR3,ANXA3,LIPC,ALDOB,AQP1,BCHE,AREG,BMP4,SSTR4,WNT5A,SSTR2,ALPL,CTGF,KRAS,SDC1,SGK1,TAT,ANXA1,ACVR1,SLIT3,ERRFI1,AKR1C3,CDKN1A,STAR,HIF1A,CPS1,HTR1B,UBE2L3,MSTN,ADIPOQ,TYMS,CASP3,SLC18A2,SPARC,PTPRU,FAS,HMBS,AGXT,PTGS1,HNMT,MYOD1,ADCYAP1,BAX,ADAM9,FLT3,AHR,EDN1,JUNB,SLC9A3
GO:0042107	cytokine metabolic process	GO_CYTOKINE_METABOLIC_PROCESS	-0.56547910037147	-1.72940712319682	0.0105117446035385	0.169294413088568	17	CMA1,IL18,IRF7,IL17F,IFNAR1,NOD1,CEBPE,PAWR
GO:0016072	rrna metabolic process	GO_RRNA_METABOLIC_PROCESS	-0.263368419726355	-1.35910932763357	0.0109821959223753	0.176028911784358	222	RPL24,RPL38,RBFA,RPL35,RPL30,RPL9,RPL3,RPS3A,RPS19,XRN2,RPS27,RPL4,RPS11,RPL7A,RPS4Y1,WDR75,WDR46,RPS8,RPL18,NOC4L,EXOSC2,NOP10,EXOSC6,RPS24,RPL18A,UBA52,RPL15,RPS16,WDR43,RPP25,RPL5,RPS27L,EXOSC5,NSA2,RPL10A,RPS3,RPL22,RPS29,RPL26,RPL19,KRR1,SART1,EXOSC10,RPS28,RPS5,RPS17,DROSHA,EXOSC8,WDR36,PES1,DHX37,NHP2,RPF2,DDX21,PAPD5,RPL36,RPS6,DDX51,RPP21,SIRT1,RPL23A,RPP30,RPS18,FAU,RPL32,BOP1,RPLP0,RPL14,NOP14,RPS15,RRP36,RIOK3,PNO1,RPS13,THUMPD1,RPL28,RPS4X,RPL34,NOL11,LAS1L,NOLC1,RPL27,RRS1,DIMT1,RPL13
GO:0048705	skeletal system morphogenesis	GO_SKELETAL_SYSTEM_MORPHOGENESIS	-0.273193433616599	-1.38292503874663	0.0112012945965764	0.178689846502731	191	MATN1,HOXA6,NAB2,NKX3-2,OSR1,IRX5,RARA,CYP26B1,RDH10,TGFBR1,BMP4,SFRP2,HOXA3,ALPL,CTGF,T,HOXA7,WNT9A,THBS3,SERPINH1,GRHL2,FGFR2,PAPPA2,SOX11,MTHFD1L,COMP,WNT10B,SGPL1,CTNNB1,FGF18,BMPR1B,NLE1,WDR19,MSX2,FGF4,PRKRA,SMAD2,SPEF2,WWOX,ACVR2B,WNT9B,TULP3,HOXB8,NODAL,SLC39A1,TBX4,MYCN,MGP,DLG1,RAB23,AXIN1,PSEN1,MMP14,CSRNP1,WNT7A,COL11A1,NOG,IFT140,UNCX,PHOSPHO1,PAX1,HHIP,LTF,HOXD8,SATB2,MYF5,ALX4
GO:0010811	positive regulation of cell substrate adhesion	GO_POSITIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION	-0.332026311223472	-1.49499760524042	0.0112937071181006	0.178695147765204	91	VTN,CCL28,ITGA3,CCDC80,KDR,S100A10,NPNT,ALOX15,FOXF1,NPY2R,ITGB1BP1,CYR61,DMP1,CALR,SPOCK2,CCL21,CSF1,ABI3BP,TRIOBP
GO:0019935	cyclic nucleotide mediated signaling	GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING	0.434415271263097	1.60958576518702	0.0113078034682081	0.178695147765204	41	RAPGEF4,NUDT4,GUCY1B3,DGKQ,ADCYAP1R1,GLP1R,AKAP6,RAPGEF2,ADCY7,ADCY5,PDE2A,ADCY8,ADCY9,ADCY4,SOX9,PDE7A,CD36,PRKG1,EPHA5,ADM
GO:0098868	bone growth	GO_BONE_GROWTH	-0.541098855828998	-1.70422008637772	0.0113819019071202	0.179025615978349	19	MATN1,RARA,THBS3,COMP,OSTN,MSX2,LEP
GO:0032007	negative regulation of tor signaling	GO_NEGATIVE_REGULATION_OF_TOR_SIGNALING	0.482168849612898	1.64792670882134	0.0115538357639586	0.180884703169696	29	FLCN,TSC1,TSC2,FNIP1,PRKAA2,NPRL3,TMEM127,MAPKAPK5,RNF152,PDCD6,DEPDC5,AKT1S1,EPM2A,UBR2,DDIT4,CRYBA1
GO:0016126	sterol biosynthetic process	GO_STEROL_BIOSYNTHETIC_PROCESS	0.429514062385379	1.59993055950887	0.0116425992779783	0.181430505415162	42	IDI2,CNBP,LSS,HMGCR,MVD,CYP51A1,PRKAA2,CYB5R1,GGPS1,MSMO1,INSIG1,HMGCS2,HMGCS1,SQLE,IDI1,FDFT1,NSDHL,APOA5
GO:1903320	regulation of protein modification by small protein conjugation or removal	GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL	0.271049152829438	1.35932903180294	0.0117751862649822	0.182651045935161	249	DCUN1D2,PCID2,TRIP12,ZYG11B,CDC26,RNF40,FBXW7,PRICKLE1,PSMD11,ADRB2,LRRK2,PIN1,N4BP1,RNF111,PSMD2,UBE2N,PSMC6,SASH1,CAPN3,MAD2L1,RNF180,GOLGA2,PINK1,FZR1,HDAC4,FEM1B,SUFU,FEM1A,BTRC,CAV3,PTEN,PELI1,CDK5RAP3,ANAPC1,PSMC5,PSMB7,LIMK1,PSME4,UBR5,GORASP1,GTPBP4,DNAJA3,DNAJB2,AIMP2,HAMP,MTOR,ANAPC11,PSMA8,PARK7,CDK1,PSMD8,VCP,PSMB10,PIAS3,TRIB3,MALT1,PSMD3,PSMB1,SMAD7,PSMA5,TPR,PSMB9,PRKCE,PIAS4,UBXN1,TSPYL5,CDC20B,MTA1,COMMD1,EGF,CHFR,RASSF1
GO:0050773	regulation of dendrite development	GO_REGULATION_OF_DENDRITE_DEVELOPMENT	0.325476436268554	1.46444798300642	0.0122261931225526	0.188776908488588	113	CPEB3,SHANK3,NLGN3,CDKL5,IL1RAPL1,TNIK,HDAC2,PAFAH1B1,TIAM1,RAB21,LRRK2,VLDLR,KIAA0319,SHANK1,ARF1,GSK3B,RAPGEF2,OBSL1,PTEN,CFL1,PPP1R9A,NFATC4,GORASP1,EZH2,DNM3,FBXO31,MTOR,CAMK2B,EPHA4,ZMYND8,IL2,SDK1,BHLHB9,BCL11A,OPA1,ARF6,MARCKS,ITPKA,PQBP1,MEF2C,TRPC6,PACSIN1
GO:0003018	vascular process in circulatory system	GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM	0.300905831010473	1.41856114762165	0.0123411247862101	0.189681397399011	154	P2RY1,AMOT,AGT,PTPRM,PPARD,TRPM4,ADRB1,SERPINF2,VIP,NPY1R,ADRB2,P2RY2,HRH2,ATP1A2,ADRA2C,ABR,VEGFB,GJA1,HMGCR,GUCY1A3,ARHGAP35,UCN,DOCK4,SLC8A1,AGTR2,PDE2A,CX3CL1,ESR2,GJA5,KCNA5,TEK,ACE2,SOD2,CTNNBIP1,VEGFA,SOD1,MYLK3,ADORA2B,MKKS,PTAFR,CD38
NA	chromatin modification	GO_CHROMATIN_MODIFICATION	0.239005520764548	1.28284044342413	0.0125009528165257	0.190149648965561	482	WDR82,TET1,GSG2,DPF3,SMARCB1,TRIM16,PHF2,UHRF1,HILS1,NASP,JARID2,KDM3B,RNF40,CENPK,NPM1,HDAC9,ZNF304,PAF1,EYA4,HDAC2,CENPA,PRDM2,PRMT7,KDM2B,DYDC1,ESR1,MEAF6,CREBBP,UBE2N,CHD6,MCRS1,KAT7,SFMBT1,DR1,SUV39H1,RERE,TAF1,EED,NSD1,EYA1,HMGA1,BAP1,HELLS,HDAC4,KAT8,CHD7,WHSC1L1,PBRM1,JAK2,SMARCD3,REST,PRKAA2,HUWE1,CHD8,MED24,HIST1H4F,KDM5A,RRP8,SETDB1,KAT6A,SMYD1,PSME4,KAT2A,EZH2,PPP5C,TLK2,HIST1H2BA,EZH1,EP300,PHF21A,BRD3,TET2,GFI1B,ING3,DAPK3,MBD3L1,RBBP5,SETD7,CENPN,NCOR1,SETD1B,MECOM,HDAC6,CDK1,BRMS1,HSF4,BRD1,ATXN7,ATF2,NAA50,NCOA3,PKN1,CTCFL,HMG20A,LDB1,ASF1B,SOX9,SFPQ,PRDM9,SETDB2,SPI1,MSL3P1,L3MBTL4,HDAC11,ATRX,BPTF,CRTC2,BCOR,BAG6,CECR2,NCOA1,ENY2,CENPI,UBN1,BAZ2A,JMJD6,ACTL6B,RNF168,SETD3,ANP32E,HMGN3,ASF1A,KDM5C,CBX3,PCGF2,MTA1,UBE2B,UBR2,SATB1,NR3C1,CHD9,GATAD2B,HDAC5,KAT6B,SCMH1,SUPT7L,BABAM1,BRD9,USP34,HIST1H4A,ING5,HIST1H1D,CBX6,BRCA2,PAXIP1
GO:0010574	regulation of vascular endothelial growth factor production	GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_PRODUCTION	-0.468701126023628	-1.65158973419628	0.0125400862545615	0.190149648965561	29	C3,SULF1,SULF2,IL6ST,HPSE,HIF1A,EIF2AK3,C5AR1,C5,NODAL,ISL1,CYP1B1,ARNT,NOX1,IL1A
GO:0009306	protein secretion	GO_PROTEIN_SECRETION	-0.31424355545791	-1.45724758733878	0.0125410641920246	0.190149648965561	108	STEAP3,CHI3L1,SCG2,CCL19,UBE2Q1,TRAF3IP2,ILDR2,ARL4D,PDIA4,GATA3,ANXA1,CANX,S100A12,STXBP3,PCLO,EIF2AK3,RAB13,LEP,SLC18A2,SMAD2,ABCA1,LTBP2,GPR119,SLC30A8,NLRP3,GAL,ACVR2B,POU2F2,CYB5R4,TLR2,MON1A,VTCN1,GPAM
GO:0006605	protein targeting	GO_PROTEIN_TARGETING	-0.235679301118389	-1.28877061874985	0.0126024817194771	0.190224006581883	364	GDF5,RPL24,SRP72,RPL38,PIP5K1A,NLGN1,PEX10,RPL35,PEX5L,SEC63,PRKG2,RPL30,KATNB1,HOMER3,RGPD3,RPL9,AP3M1,PRKCI,RPL3,RPS3A,TMED2,RPS19,TSPO,SEC61G,RPS27,TIMM10,FUT10,RPL4,ANXA2,TRAM1,IPO5,TIMM9,RPS11,RPL7A,SSR1,RPS4Y1,VPS25,CTNNB1,SLC25A6,STAT3,MTX1,TOB1,RPS8,AKR1C3,RPL18,KPNA7,SPRN,SSR2,SNF8,RPS24,RPL18A,UBA52,RHOD,RPL15,RPS16,AP1S3,RPL5,RPL10A,RPS3,SORL1,NUP50,TOMM34,LTBP2,RPL22,FGF9,SRP54,GCC2,SPCS1,RPS29,OPRD1,RPL26,RPL19,KCNB1,TOMM5,INPP5K,SRP14,SNX16,RPS28,F2R,RPS5,HSP90AA1,RPS17,CHM,MFF
GO:0048871	multicellular organismal homeostasis	GO_MULTICELLULAR_ORGANISMAL_HOMEOSTASIS	-0.255180819402909	-1.33644975913179	0.0127669573390423	0.190829117774026	248	MC3R,CLDN1,SERPINA3,MUC2,SCNN1A,RBP4,SFN,SLC28A3,AZGP1,TNFSF11,CNGB1,ACADL,CD7,CYP26B1,IQCB1,AQP1,MYO5B,ILDR2,HRNR,AQP3,POTEE,CTGF,FGF7,KRAS,CIDEA,FLG,ACTG1,ALOX12B,MUC6,CTNNB1,STAT3,USH1G,NR4A3,CSF1,PRLH,TMEM79,TULP1,PRDM14,AMPD2,AIPL1,PRKAR2B,CDH3,SCNN1G,PIGR,PRKAR1B,CTSK,SCNN1B,ADCY2,PRKACG,CYP4F2,ZNF675,TLR9,CD34,BAX,KRT16,IGKC,BARD1,F2R
GO:0097485	neuron projection guidance	GO_NEURON_PROJECTION_GUIDANCE	-0.270635570190057	-1.37102853963504	0.0127871420990119	0.190829117774026	192	SEMA3F,LHX9,SEMA3C,LHX4,EZR,KIF5A,EFNB3,GBX1,FLRT3,WNT5A,FMOD,GAP43,KRAS,GATA3,UNC5D,NEO1,EFNA5,GBX2,SEMA3A,SEMA3B,FLRT2,UNC5A,OTX2,PLXNB2,SPTBN4,EVL,BMPR1B,PLXNA2,SLIT3,FEZF1,ISL2,NR4A3,ROBO2,ARTN,EPYC,FZD3,USP33,CDK5,CDH4,EXT1,LMX1A,BOC
GO:0030178	negative regulation of wnt signaling pathway	GO_NEGATIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY	0.288895142830246	1.39440326149893	0.0128126502129917	0.190829117774026	183	RAPGEF1,CXXC4,PRICKLE1,TMEM88,LRP6,DVL2,RNF213,PSMD11,PPP2R3A,GRB10,CCND1,PSMD2,PSMC6,TSC2,CDH2,SOX2,WIF1,GSK3B,DKK3,CHD8,AES,RGS20,PSMC5,PSMB7,MED12,NFATC4,PSME4,LATS1,SHH,ANKRD6,FOXO1,NKX2-5,ZNRF3,CTNNBIP1,PSMA8,FZD6,SOX17,DKK4,PSMD8,PSMB10,APC,LIMD1,SOX9,WNT11,PSMD3,PSMB1,CSNK1A1,MDFI,PSMA5,MLLT3,PSMB9,G3BP1
GO:0014896	muscle hypertrophy	GO_MUSCLE_HYPERTROPHY	0.483745709999919	1.639138757346	0.0128920179208192	0.191165340623249	28	AGT,HDAC2,TIAM1,RYR2,HDAC4,KLF15,TCAP,AGTR2,TTN,CYBA,HEY2,INPP5F,MEF2C,MYOCD,CSRP3
GO:0071229	cellular response to acid chemical	GO_CELLULAR_RESPONSE_TO_ACID_CHEMICAL	-0.280579769170725	-1.38687508071562	0.0131274707242485	0.193106612200365	162	ASS1,WNT6,SHMT1,OSR1,RARA,CYP26B1,SNW1,FFAR3,AQP1,WNT5A,T,WNT9A,CEBPB,PTK7,SOCS1,IPO5,KLF4,XBP1,WNT10B,P2RY4,AKR1C3,DGAT2,EGFR,WNT7B,HIF1A,CPS1,LEP,CCNB1,PPARG,ABCA1,PTGER2,RAPGEF3,LTK,FAS,CAPN2,RRAGC,CPEB4,WNT9B,PKD2,EDN1,PDGFD,TESC,PTGER4,RET,SMARCD1,LAMTOR1,SERPINF1,WNT3,PTGFR,ACACA,SH3BP4,AKR1C1
NA	inorganic ion import into cell	GO_INORGANIC_ION_IMPORT_INTO_CELL	-0.580365984620014	-1.70973917205214	0.0131376750427461	0.193106612200365	15	STEAP3,STEAP1,SLC31A1,SLC8A3,STEAP1B,PAWR,STEAP4,PICALM
GO:0010644	cell communication by electrical coupling	GO_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING	0.588770511632137	1.69181291590642	0.0132902098552018	0.194499332054822	15	PRKACA,RYR2,ATP1A2,GJA1,PKP2,SLC8A1,CACNA1C,GJA5,ATP1A3,ATP1B2
GO:0071300	cellular response to retinoic acid	GO_CELLULAR_RESPONSE_TO_RETINOIC_ACID	-0.36824940700287	-1.53271992338166	0.0134696304427369	0.196271757879881	60	WNT6,OSR1,RARA,CYP26B1,SNW1,AQP1,WNT5A,T,WNT9A,PTK7,KLF4,WNT10B,WNT7B,LEP,PPARG,ABCA1,LTK
GO:0048706	embryonic skeletal system development	GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT	-0.30836818919274	-1.44344124606319	0.0137309693582579	0.199052769134136	114	PAX7,HOXA6,RBP4,SULF1,NKX3-2,DLX1,OSR1,IRX5,RDH10,TGFBR1,BMP4,WNT5A,HOXA3,T,HOXA7,WNT9A,GRHL2,FGFR2,SOX11,MTHFD1L,CTNNB1,SULF2,WDR19,SMAD2,SPEF2,FGF9,EXT1
GO:0042176	regulation of protein catabolic process	GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS	0.249992716748794	1.30634664705607	0.013844565421438	0.199052769134136	362	GNA12,PRKACA,PCID2,RNF144B,CDC26,RNF40,FBXW7,UBQLN4,OSBPL7,TRIB2,ATPIF1,PRICKLE1,CSNK2A1,VIP,PSMD11,PPP2R3A,EDEM2,LRRK2,PIN1,N4BP1,PSMD2,PSMC6,RAD23A,NEDD4L,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,PCSK9,PINK1,FZR1,GJA1,USP13,VPS11,SUFU,GRIN2C,BTRC,GSK3B,CAV3,PTEN,CDK5RAP3,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,DERL3,TLK2,DNAJB2,SGTA,SHH,FAM83D,RNF144A,RNF125,FOXO1,ANAPC11,OPHN1,YOD1,TNF,ARIH2,PSMA8,CDKN1B,PARK7,SOCS4,SOX17,CDK1,PSMD8,TRIM32,VCP,TIMP3,PSMB10,GGA3,APC,DEDD,RHBDD3,TRIB3,FAF1,SOX9,DLGAP5,PBK,SF3B3,RDX,PSMD3,PSMB1,BAG6,CSNK1A1,SMAD7,SMAD3,OAZ1,RHBDD1,SERPINB12,SUMO2,USP14,PSMA5,KLHL22,SUMO1,TPR,PSMB9,MAD1L1,USP5,UBXN1,NDUFA13,COMMD1,EGF,CHFR,ESPL1
NA	positive regulation of vasodilation	GO_POSITIVE_REGULATION_OF_VASODILATION	0.471767326061949	1.62593597745905	0.0138627948123963	0.199052769134136	30	AGT,PTPRM,PPARD,VIP,ADRB2,GJA1,UCN,AGTR2,ESR2,GJA5,PTAFR,SCPEP1,ADM,UTS2,NOS2
GO:0030029	actin filament based process	GO_ACTIN_FILAMENT_BASED_PROCESS	0.243475835908658	1.29098034025142	0.0138970293364593	0.199052769134136	419	AMOT,TAOK2,CORO6,EPB41,OBSCN,ARHGAP26,ANK2,TESK2,LDB3,CFLAR,MSRB2,SSH2,TNIK,DLC1,FRY,PAFAH1B1,SCN5A,ROCK2,FGD6,CACNA2D1,RYR2,FHL3,LIMCH1,MICAL3,FRYL,NEDD4L,CAPN3,MYBPC3,KCNJ2,BMP10,ARHGEF2,GHSR,ARAP1,PACSIN2,MYL1,MOB2,LMOD1,LMOD3,ABR,CTNNA1,XIRP2,GJA1,ARF1,MYO9B,ABLIM3,INPPL1,ADD1,JAK2,CAV3,OBSL1,SPIRE1,TCAP,DMD,CFL1,PKP2,PRKAR1A,ACTR3B,PALLD,PPP1R9A,LIMK1,MYPN,TTN,CDC42BPA,KCNH2,TNNI3,MYH7,TPM2,TRIP10,MTSS1,RHOF,INSRR,CAPZB,PRKCZ,WASL,TMOD1,FNBP1L,CACNA1C,MYL2,GJA5,KCNA5,IKBKB,OPHN1,FARP2,MKLN1,S1PR1,TNF,NKX2-5,TRIM32,PDLIM7,JMY,CDC42BPG,FHOD3,PHACTR1,EPB41L4B,ALDOA,TNNT2,MYLK3,SYNE2,SSH1,IQSEC1,TNNC2,DES,ELMO1,GJC1,PIP5K1C,FLNB,FGF12,FGD5,CFL2,BCL6,TNNT3,PRKG1,FOXJ1,GAS2L3,PFN2,SNTA1,ARF6,MARCKS,PROX1,ITPKA,XIRP1
GO:0050766	positive regulation of phagocytosis	GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS	-0.405735040186564	-1.5794441547437	0.0141646244126178	0.201173526467812	44	C3,C4A,C2,ANO6,LMAN2,CALR,PYCARD,TULP1,ABCA7,PPARG,PROS1,MBL2
GO:0060350	endochondral bone morphogenesis	GO_ENDOCHONDRAL_BONE_MORPHOGENESIS	-0.405660971642726	-1.57915582093709	0.0141646244126178	0.201173526467812	44	MATN1,NAB2,RARA,BMP4,ALPL,THBS3,SERPINH1,COMP,FGF18,BMPR1B
GO:0035051	cardiocyte differentiation	GO_CARDIOCYTE_DIFFERENTIATION	0.342396682849903	1.48300304825194	0.0143107730248875	0.201648396157636	90	AGT,TBX2,TSC1,HAND2,BMP10,CAV3,OBSL1,REST,TCAP,SLC8A1,AKAP13,AGTR2,TTN,KAT2A,MYL2,MTOR,TBX5,NKX2-5,FHL2,RXRA,MAPK1,SOX17,CDK1,VEGFA,FHOD3,MYLK3,HEY2,LRRC10,PROX1,TBX3,NOX4,MEF2C,SRF,TWIST1,SGCB,ACTN2,RARB,MYOCD,ECE2,NEBL,CSRP3
NA	regulation of vasodilation	GO_REGULATION_OF_VASODILATION	0.417293424911964	1.5708644335485	0.0143178748311571	0.201648396157636	44	P2RY1,AGT,PTPRM,PPARD,VIP,ADRB2,P2RY2,GJA1,HMGCR,UCN,AGTR2,ESR2,GJA5,ACE2
GO:0018200	peptidyl glutamic acid modification	GO_PEPTIDYL_GLUTAMIC_ACID_MODIFICATION	-0.471368177700034	-1.63192024219797	0.0148241150686138	0.207233382700342	27	TTLL4,AGBL5,TTLL7,F7,TTLL1,AGBL3,F2,PROS1,CEP41,VKORC1,VKORC1L1,NAA10
GO:0032331	negative regulation of chondrocyte differentiation	GO_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION	-0.550900289496495	-1.68482068426679	0.01483756542804	0.207233382700342	17	GDF5,NKX3-2,EFEMP1,TGFBR1,BMP4,WNT9A,CTNNB1,PTHLH
GO:0009262	deoxyribonucleotide metabolic process	GO_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS	-0.44472213319188	-1.61840859205413	0.0150924161163069	0.209921787799541	33	DTYMK,SHMT1,MPG,NUDT18,DUT,GUK1,SMUG1,NEIL2,RRM2B,TYMS,NT5M
GO:0070873	regulation of glycogen metabolic process	GO_REGULATION_OF_GLYCOGEN_METABOLIC_PROCESS	0.458959604138848	1.60679492841111	0.0154067491030941	0.213412006094711	32	AKT2,GRB10,GSK3B,IRS1,GCK,PPP1R3B,PPP1R3F,MTOR,PPP1CB,HMGB1,PPP1R3E,PASK,PTH,PHKG2,EPM2AIP1,SORBS1
GO:0045292	mrna cis splicing via spliceosome	GO_MRNA_CIS_SPLICING_VIA_SPLICEOSOME	0.558318229471766	1.6586024775501	0.0154738878143133	0.213463550749913	17	NCBP1,SNRNP200,PRPF39,SFSWAP,NCBP2,SRSF1,SNRPC,DDX23,WBP11,RBM22,SRSF12,RNF113B
GO:0034250	positive regulation of cellular amide metabolic process	GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS	0.333710398536464	1.46394392111223	0.0155450269746853	0.213569635905268	97	CPEB3,LARP4B,METTL3,DDX3X,EIF2B5,NPM1,C1QBP,PRR16,BARHL2,RMND1,ESR1,SAMD4A,NSMAF,PINK1,FAM129A,UCN,DDX39B,ABCF1,KHDRBS1,EP300,MTOR,YTHDF2,TNF,RXRA,NCOR1,MAPK1,LRRTM3,IMPACT,PTAFR,PASK,IMP3
GO:0042445	hormone metabolic process	GO_HORMONE_METABOLIC_PROCESS	-0.287141739041483	-1.39312111481751	0.0157037182669386	0.214872827993965	143	CMA1,RBP4,HSD17B6,SCG5,CYP26B1,RDH10,LRAT,CPA3,SRD5A3,CYP11A1,FDX1L,DUOX2,CYP26A1,TG,FOXA1,UGT2B7,FDXR,PCSK1N,SGPL1,AKR1C3,DGAT2,PCSK1,STAR,RDH8,CHST8,CYP21A2,RBP1,LEP,RDH13,MME
GO:1903035	negative regulation of response to wounding	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING	-0.287206837951453	-1.3921869896364	0.0158734052993131	0.21631531270238	142	VTN,SMPDL3B,PTGIS,TYRO3,PTPN2,GATA3,FOXF1,C1QTNF1,ANXA5,SERPING1,RPS19,ANXA2,KLF4,NLRP6,CNR2,F2,PLAUR,SAA1,TNFRSF1A,ADAMTS18,ADIPOQ,MMP26,CERS2,NOV,PPARG,SERPINB2,NR1H3,PROS1,PGLYRP1,HGF,MVK,NLRP3,NLRP12,CD34,ADCYAP1,CASK,ABAT,IL2RA,EDN1,ELANE,PTGER4,SOCS3,IL20RB,CD276,CUEDC2,SERPINF1,SERPINC1,IL10,FGF2,THBD,ISL1
GO:0019933	camp mediated signaling	GO_CAMP_MEDIATED_SIGNALING	0.457638435096104	1.60216958078071	0.015989510298483	0.217018918002797	32	RAPGEF4,DGKQ,ADCYAP1R1,GLP1R,AKAP6,RAPGEF2,ADCY7,ADCY5,PDE2A,ADCY8,ADCY9,ADCY4,SOX9,PDE7A,EPHA5,ADM
GO:0070830	bicellular tight junction assembly	GO_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY	-0.464550178222418	-1.62303723048779	0.0161308118366176	0.217848410757946	28	CLDN1,PARD6B,OCLN,GRHL2,PRKCI,MPP7,MARVELD2,RAB13,MPP5
GO:0006635	fatty acid beta oxidation	GO_FATTY_ACID_BETA_OXIDATION	0.406796228884677	1.55283780710646	0.0161800661584927	0.217848410757946	47	SLC25A17,DECR1,IVD,PPARD,ACOX3,ACAD9,ACADM,ACAD10,HADH,ECI2,ETFA,PEX7,ACOT8,HADHB,ECHS1,GCDH,ACADVL,HADHA
GO:0048814	regulation of dendrite morphogenesis	GO_REGULATION_OF_DENDRITE_MORPHOGENESIS	0.363733650638772	1.50620105020125	0.0162928480744816	0.218492934735877	70	SHANK3,NLGN3,CDKL5,IL1RAPL1,TNIK,PAFAH1B1,TIAM1,RAB21,LRRK2,GSK3B,RAPGEF2,OBSL1,PTEN,CFL1,PPP1R9A,NFATC4,GORASP1,DNM3,FBXO31
GO:0007548	sex differentiation	GO_SEX_DIFFERENTIATION	-0.253581889048016	-1.32227853921837	0.0168093466212172	0.22452484415483	240	LHX9,KIF18A,RBP4,TYRO3,AMHR2,OSR1,IRX5,RARA,WT1,RDH10,TGFBR1,BMP4,WNT5A,SFRP2,NUPR1,FGF7,WNT2B,MGST1,CBX2,GATA3,DMRT1,CEBPB,FSHR,SDC1,ADAM15,UTF1,FANCF,INSL3,SGPL1,REC8,CTNNB1,BMPR1B,BOK,SLIT3,AKR1C3,WDR19,STAR,ROBO2,RAB13,BMP5,LEP,COL9A3,CDKL2,FGF9,FAS,MEA1,PRKACG,SOX15,ADCYAP1,BAX,HMGB2,HSD17B10,ACVR1B,AHR,WNT9B,TMF1,BASP1,AFP,FSHB,GPR149,FOXO3,HNF4A,INHBA,SIRT1,ARID4A,LRRC6,STRA6,FOXL2,MMP19,MMP14,BCL2,PLA2G4A,WNT7A,NRIP1,FNDC3A,GATA6,TLR3,KLHL10,MAMLD1
GO:0001503	ossification	GO_OSSIFICATION	-0.253586314024276	-1.32105967903657	0.0171037924670531	0.22755480412688	238	SLC34A1,RPL38,NAB2,CCL3,TNFSF11,UFL1,BMP4,ATP6V1B1,BMP2,RYR1,ALPL,CTGF,TUFT1,ANO6,DUOX2,SND1,THBS3,ALOX15,FGFR2,NR1I3,CYR61,CREB3L1,DMP1,GDF10,RPS11,DSPP,MRC2,MEN1,FGF18,FIGNL1,CAT,OSTN,CHRDL2,CSF1,EGFR,MSX2,EIF2AK3,CDH11,BMP5,LEP,PTHLH,RSPO2,CBFB,CLEC5A,SPARC,MN1,FGF9,EXT1,MINPP1,CTSK,RSL1D1,FASN,EPHA2,WWOX,TMSB4X,TPM4,RHOA,JUNB,RASSF2,DDX21,PLXNB1,MGP,ASGR2,CHRDL1,MMP14,BCL2,WNT3,COL11A1,NOG,RPS15,SEMA7A,SPP1,PHOSPHO1,RRBP1,TWSG1,FBXL15,PKDCC,LTF,SNAI2,SATB2,MYF5,VCAN,FOXC1,KAZALD1
GO:0007029	endoplasmic reticulum organization	GO_ENDOPLASMIC_RETICULUM_ORGANIZATION	-0.431165370698528	-1.5919763314188	0.0173808677098151	0.230330711461565	35	BNIP1,RTN4,REEP1,EIF2AK3,RAB10,STX18,ATL3,RTN3,WRB,ATL1,SEC61A1,GET4,ASNA1,TOR1AIP2,LMAN1
GO:0007517	muscle organ development	GO_MUSCLE_ORGAN_DEVELOPMENT	0.264725861187295	1.3294186140624	0.0175160266787541	0.230409271911544	252	LAMA2,XK,UBE4B,SRPK3,SGCA,DNER,CFLAR,ANKRD2,GTF3C5,MSC,SGCD,TAZ,SMTN,HLX,SGCG,RYR2,SVIL,FHL3,CAPN3,MYBPC3,BCL9L,HIVEP3,BMP10,MKL2,ZFHX3,CTF1,PLAGL1,XIRP2,USP2,CAV3,TCAP,DMD,PKP2,ZBTB42,MURC,ZNF689,SMYD1,TTN,TNNI3,MYH7,KLHL31,EGLN1,SIX1,DLL4,EP300,MYLK,TCF21,MYL2,UNC45B,TBX20,S1PR1,NKX2-5,EMD,RXRA,NCOR1,HOMER1,MEF2D,TNNT2,CNTFR,LEMD2,HEY2,TMEM8C,PAX3,FLNB,SMAD7,LAMA5,FOXO4,GPCPD1,PROX1,MSX1,MED1,HOXD10,VGLL2,NR2F2,MEF2C,UTRN,ITGB1BP2,TWIST1,SGCB,MAFF,DSP,PTCD2,TGFBR3,P2RX2,SAP30,CHODL,SMO,IGFBP5,FOXC2,PHOX2B,ANKRD33
GO:0045932	negative regulation of muscle contraction	GO_NEGATIVE_REGULATION_OF_MUSCLE_CONTRACTION	0.527371894111573	1.63701774262826	0.0175980754996299	0.230409271911544	20	PDE5A,ADRB2,ATP1A2,ADRA2C,GUCY1A3,DOCK4,SOD1,ADORA2B,PRKG1,TNNT1,ATP2A1,PIK3CG
GO:0033628	regulation of cell adhesion mediated by integrin	GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN	-0.417916683412237	-1.57197892791746	0.017690791830885	0.230409271911544	38	DPP4,SFRP2,MUC1,ITGB1BP1,CCL21,PIEZO1,EPHA2,ADAM9,TESC,RET,PODXL,SWAP70,ZAP70,CYP1B1,PDE3B,SNAI2
GO:0016458	gene silencing	GO_GENE_SILENCING	0.286250065319134	1.37339319804834	0.0177298482909889	0.230409271911544	175	HILS1,HIST1H2AB,ADAR,METTL3,POM121,WTIP,HDAC2,NCBP1,TNRC6C,ZCCHC11,DYDC1,SUV39H1,NUP85,HIST1H3G,SMAD1,HIST1H3B,TNRC6A,HELLS,RAE1,HENMT1,CELF1,SIRT4,HIST1H4F,CLP1,SIRT5,RRP8,CNOT6L,LIN28B,H2AFZ,H3F3A,POLR2I,NUP188,TNRC6B,NCBP2,SRRT,MBD3L1,IPO8,H2AFV,HNRNPA2B1,LIMD1,MOV10,DICER1,HIST1H3E,TDRKH,CNOT8,MSL3P1,SMAD3,BAZ2A,TSN,TPR,AAAS,UBE2B,UBR2,POLR2C,POM121C,CNOT1,HDAC5,SCMH1
GO:0035909	aorta morphogenesis	GO_AORTA_MORPHOGENESIS	0.526780390527227	1.63518165338419	0.0177831236121392	0.230409271911544	20	TBX2,EYA1,NPRL3,SIX1,DLL4,MYLK,HEY2,FGF8,PROX1,SRF,SEC24B
GO:0030104	water homeostasis	GO_WATER_HOMEOSTASIS	-0.353202047371911	-1.49239120581143	0.0178361019337846	0.230409271911544	65	CLDN1,SCNN1A,SFN,CYP26B1,AQP1,MYO5B,HRNR,AQP3,AQP8,FLG,ALOX12B,TMEM79,PRKAR2B,SCNN1G,PRKAR1B,SCNN1B,ADCY2,PRKACG,CYP4F2,KRT16
GO:0086091	regulation of heart rate by cardiac conduction	GO_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION	0.471776867970671	1.59858316699111	0.017865959586724	0.230409271911544	28	ANK2,CTNNA3,SCN5A,CACNA2D1,KCNJ2,PKP2,KCNH2,CACNA1C,GJA5,KCNA5
GO:0019722	calcium mediated signaling	GO_CALCIUM_MEDIATED_SIGNALING	0.345889649001173	1.47017163060925	0.0180085488052694	0.231361737704339	81	PRKACA,RCAN2,ANK2,DMPK,LRRK2,NUDT4,CALM3,RYR2,ATP1A2,HRC,HDAC4,PLCE1,DMD,CXCR3,PLN,GPRC6A,PPP1R9A,SLC8A1,NFATC4,LAT2,CALM1,NCALD,PPP3R1,CACNA1C,SELP,NMUR2,PLCG1,MCTP1,BTK,ATP2A2,CAMKK2
GO:1901019	regulation of calcium ion transmembrane transporter activity	GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.37420185732811	1.50797631417902	0.0181840738705847	0.231870631489637	61	PRKACA,OPRL1,ANK2,DRD4,CALM3,CACNA2D1,RYR2,S100A1,ATP1A2,DRD2,HRC,AKAP6,CAV3,DMD,PLN,CALM1,AHNAK
GO:0019233	sensory perception of pain	GO_SENSORY_PERCEPTION_OF_PAIN	-0.345143522664788	-1.48140548779137	0.0182259182259182	0.231870631489637	70	MRGPRX2,SCN3B,NMU,LXN,CNR1,BDKRB1,MMP24,OPRM1,TACR1,GRIN2A,CNR2,CHRNB2,MME,CDK5,IAPP,EDNRB,OPRD1,KCNA1,PTGS1,ADCYAP1,HOXB8,EDN1,PAWR,TRPA1,HTR2A,UCHL1,NIPSNAP1,GIP,CRHR2,ALOXE3,FAM134B,CALCA,KCNA2,SCN10A,ALOX5,ADORA1,GRM1,NGFR,EPHB1,NTRK1,TAC1,KCND2
GO:0031341	regulation of cell killing	GO_REGULATION_OF_CELL_KILLING	0.385022141772149	1.51924222776224	0.018254817987152	0.231870631489637	55	BAD,STAT5B,CRTAM,XCL1,CEACAM1,HLA-B,CCR2,IL4,MICA,P2RX7,IL11,SH2D1A,LILRB1,IL21,PIK3R6,AP1G1,NOS2,HLA-E,TAP1,IL12RB1,PPP3CB,STX7,RASGRP1
GO:0007423	sensory organ development	GO_SENSORY_ORGAN_DEVELOPMENT	-0.220139731075105	-1.23416310723876	0.0184703433922997	0.232864109121561	471	GNG8,WNT6,RPL38,RBP4,SOX3,PAX8,NKX3-2,OSR1,IRX5,TRAF3IP1,RARA,WT1,CYP26B1,PDZD7,RDH10,CDON,EFEMP1,TGFBR1,MFAP2,BMP4,WNT5A,MYO15A,ATP6V1B1,BMP2,GPM6A,SIX6,PAX4,WNT2B,DUOX2,NEUROG1,GATA3,WNT9A,LRTOMT,PTK7,GRHL2,PRKCI,FGFR2,PRSS56,BBS7,SOX11,PDE6C,SKIL,IMPDH2,GBX2,GRXCR1,ROM1,OTX1,KLF4,MAB21L2,ATP2B2,WNT10B,PRPH2,CTNNB1,GNAT1,BMPR1B,STAT3,DFNA5,USH1G,CEBPA,SLC17A7,NR4A3,WDR19,EGFR,SLC25A25,WNT7B,HIF1A,TULP1,ATF6,ADAMTS18,HMX3,FZD3,PRKRA,RDH13,NRL,SPARC,ZNF513,FGF9,CCNA2,BCAR3,DLX6,KCNQ4,BAX,EPHA2,ACVR2B,RS1,ARHGEF15,WNT9B,TULP3,NPHP1,BNC2,SHROOM2,MAFB,PITX3,RP1L1,EDN1,PYGO2,NKD1,NEUROD4,POU4F2,KCNK2,GNGT1,DLG1,INHBA,SIPA1L3,AXIN1,PSEN1,RET,LAMC3,PTF1A,STRA6,ATOH7,ATP2B1,FOXL2,HPCA,CHRDL1,SERPINF1,PLS3,GRM6,GABRB2,ABCB5,BCL2,ANP32B,SDK2,CYTL1,SLC7A11,WNT7A,SMOC1,PTPRQ,RAC1,TSKU,COL11A1,DDR1,NOG,BLOC1S3,PRDM1
GO:0051965	positive regulation of synapse assembly	GO_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY	-0.373445303460271	-1.5201743410763	0.0184713954650793	0.232864109121561	54	LRRN1,SLITRK2,NLGN1,AGRN,FLRT3,SLITRK4,LRRC4B,EFNA5,CBLN2,TPBG,FLRT2,SRPX2,FLRT1,CLSTN3
GO:0046457	prostanoid biosynthetic process	GO_PROSTANOID_BIOSYNTHETIC_PROCESS	-0.531936916022069	-1.65190555234496	0.0185935637663886	0.233529610588298	18	PTGIS,TBXAS1,AKR1C3,PLA2G4F,PTGS1,MIF,EDN1
GO:0034308	primary alcohol metabolic process	GO_PRIMARY_ALCOHOL_METABOLIC_PROCESS	-0.404552160385367	-1.54959754941971	0.0187267595537834	0.234328151145112	41	RBP4,ALDH3B1,HAO1,RDH10,LRAT,ALDH3A2,AKR1C3,DGAT2,RDH8,RDH13,ALDH3B2,RETSAT,PECR
GO:0009081	branched chain amino acid metabolic process	GO_BRANCHED_CHAIN_AMINO_ACID_METABOLIC_PROCESS	0.507499925432257	1.61650113445278	0.0190385004879306	0.237346639416202	22	IVD,HIBCH,STAT5B,MCCC2,AUH,DLD,ACAT1,BCKDK,DBT,ACADSB,BCKDHA,BCAT2,ALDH6A1,PPM1K
GO:0034340	response to type i interferon	GO_RESPONSE_TO_TYPE_I_INTERFERON	0.36657944859958	1.49717774552925	0.0191293922671415	0.2375997578273	65	ADAR,RSAD2,IRF2,XAF1,IRF6,SP100,OAS2,IFIT2,IFI27,HLA-B,IFIT1,IP6K2,OASL,HLA-H,TYK2,OAS3,IRF1,OAS1,GBP2,HLA-F,IFNA21,SHMT2,C19orf66,IFNA4,IRF8,IFIT3,HLA-E,STAT1,IFNA10
GO:0014014	negative regulation of gliogenesis	GO_NEGATIVE_REGULATION_OF_GLIOGENESIS	-0.426685938778131	-1.5754370866647	0.0193367709815078	0.239292540896159	35	DLX1,NKX6-1,ID4,BMP4,SOX11,TSPO,CTNNB1,F2,CERS2
GO:0006140	regulation of nucleotide metabolic process	GO_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS	0.277434577155788	1.3508156756466	0.0198771709700852	0.245078965147644	196	ME1,GNAS,PDE5A,OPRL1,FLCN,ATP7A,GUCY1A2,ADRB1,ATPIF1,RXFP2,DRD4,VIP,ADRB2,PPARA,CALM3,APOC3,PGAM2,DRD2,PGAM1,PPIF,ADCYAP1R1,CXCL11,GIPR,PINK1,GLP1R,GUCY1A3,HDAC4,AKAP6,VIPR2,PRKAA2,ADCY7,CXCR3,UCN,ADCY5,GCK,PDE2A,GUCA1C,EGLN1,CALM1,RAF1,P2RY13,ADCY8,ADCY9,HTR1E,CCR2,GABBR1,PARK7,NCOR1,ADCY4,VEGFA,VCP,P2RX7
GO:0060541	respiratory system development	GO_RESPIRATORY_SYSTEM_DEVELOPMENT	-0.265362092551439	-1.33775819493856	0.0200611435357134	0.245814005117839	186	PDPN,CHI3L1,ASS1,DPPA2,GNG8,RBP4,ITGA3,RARA,WT1,HSD11B1,RDH10,BMP4,WNT5A,CTGF,FGF7,KRAS,PTK7,GRHL2,FGFR2,MAP2K2,FOXF1,FOXA1,SOX11,CTNNB1,FGF18,CP,ERRFI1,DLG5,CEBPA,WNT7B,SPDEF,HOPX,SMAD2,ZIC3,RSPO2,SPEF2,SPARC,FGF9
GO:0035303	regulation of dephosphorylation	GO_REGULATION_OF_DEPHOSPHORYLATION	0.296821719555963	1.3853994844795	0.0201035535392036	0.245814005117839	144	CEP192,PPP2R5C,DLC1,PPP1R17,PPP1R16B,PPP2R3A,PPP1R14D,SMG6,ROCK2,CALM3,AKAP1,ELL,PIN1,TSC1,WNK1,DRD2,PCDH11X,SYTL2,DLG2,PINK1,AKAP6,JAK2,CDK5RAP3,CD300A,PPME1,AGTR2,PPP1R14A,CALM1,PPP1R37,IKBKB,SYMPK,TNF,SPOCD1,PPP1R12A,BAG4,PPP6R1,CD2BP2,HTT,SMAD3,UBN1,CCDC8,SFI1,DUSP26,PCIF1,MEF2C,FKBP15,ZCCHC9,SMPD1,MPHOSPH10,SMG7,GPLD1,SPPL3,PPP1R11,PPP1R26,PPP2R2B,NUAK1,PPP1R15A,PPP2R5B,PPP1R7,PPP2R1A,PPP2R5E,EIF2AK2,CRY2
GO:0048639	positive regulation of developmental growth	GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH	0.294087638217896	1.38113432148149	0.0201558720773985	0.245814005117839	150	PPARD,CDKL5,NRP1,TBX2,STAT5B,LPAR3,PAFAH1B1,ADRB2,TRPV2,HLX,PIN1,MEGF8,CACNA2D2,NEDD4L,CAPN3,YAP1,DRD2,BMP10,GHSR,NACA,MACF1,CHD7,GSK3B,AKAP6,CELF1,GH1,RASAL1,DDX39B,TGFBR2,GOLGA4,LIMK1,ITSN2,FGFR1,EP300,ERBB4,MTOR,TBX5,TBX20,CREB1,SEMA5A,CDK1,VEGFA,HEY2,MKKS,ZP3,AGR2,ACACB,L1CAM,BCL11A,PRKDC,FOXS1,FGF8,CPNE9,PROX1,NTRK3
GO:0050707	regulation of cytokine secretion	GO_REGULATION_OF_CYTOKINE_SECRETION	-0.284683902613784	-1.37537231117304	0.0202371618972952	0.245914393307926	139	APOA2,EZR,CCL3,GSDMD,CCL19,WNT5A,TNFRSF21,ANXA4,ANGPT1,GATA3,HLA-DRB5,CIDEA,ANXA1,SOCS1,XBP1,PYCARD,LPL,SAA1,IL17RC,TLR10,CLEC5A,IL17F,C5,CLEC4E,NLRP3,NLRP12,TLR9,CD34,IFNAR1,F2R,TLR2,MIF,VTCN1,HLA-DRB1,GPAM,IL17RB,MAPK11,PTGER4,ABL1,CD276,IL4R,BANK1,IL10
GO:0070741	response to interleukin 6	GO_RESPONSE_TO_INTERLEUKIN_6	-0.471990980714645	-1.60105230432739	0.0206982927204412	0.250613141356134	25	CHI3L1,PTGIS,ALDOB,ENTPD2,STAT3,IL6ST,SELPLG
GO:0050919	negative chemotaxis	GO_NEGATIVE_CHEMOTAXIS	-0.415055998559241	-1.5523956731838	0.0208868535686362	0.251989781763547	37	SEMA3F,SEMA3C,FLRT3,WNT5A,EFNA5,SEMA3A,SEMA3B,FLRT2,SLIT3,SEMA3D,SEMA3E,SEMA4B,RHOA,SEMA4A,PLXNA4
NA	fibril organization	GO_FIBRIL_ORGANIZATION	-0.535552846526265	-1.63788353455049	0.0213046675606696	0.255274413325715	17	ADAMTS3,SNCA,TNXB,B4GALT7,RIPK1,RIPK3,LTBP2
GO:0060850	regulation of transcription involved in cell fate commitment	GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_CELL_FATE_COMMITMENT	-0.508245228342862	-1.62412944391475	0.0214960184500239	0.255274413325715	20	DLX1,NKX6-1,BMP4,BMP2,CEBPB,EVX1,PPARG,ETV2
GO:0030278	regulation of ossification	GO_REGULATION_OF_OSSIFICATION	-0.271773644990515	-1.34566636716454	0.0215988640043845	0.255274413325715	164	MATN1,TPH1,CCL3,OSR1,PRKD1,ID4,AREG,BMP4,WNT5A,SFRP2,BMP2,NPNT,ANO6,CEBPB,FGFR2,CYR61,SOX11,TACR1,GDF10,ACVR1,MEN1,WNT10B,CTNNB1,BMPR1B,TOB1,IL6ST,CEBPA,OSTN,CSF1,MSX2,WNT7B,HIF1A
GO:0034754	cellular hormone metabolic process	GO_CELLULAR_HORMONE_METABOLIC_PROCESS	-0.318727510173127	-1.42993087881458	0.0216108171663727	0.255274413325715	89	RBP4,HSD17B6,CYP26B1,RDH10,LRAT,SRD5A3,CYP11A1,FDX1L,CYP26A1,UGT2B7,FDXR,SGPL1,AKR1C3,DGAT2,STAR,RDH8,CYP21A2,RBP1,RDH13,STARD5,RETSAT,HSD17B14,AFP,FSHB,AKR1B15,PLB1,HSD3B2
GO:0006904	vesicle docking involved in exocytosis	GO_VESICLE_DOCKING_INVOLVED_IN_EXOCYTOSIS	-0.425525224110482	-1.55971656858031	0.0216319459867632	0.255274413325715	34	CFTR,SNAP25,SCFD1,STXBP3,RAB13,VPS33A,UNC13B,KCNB1,STXBP1,VPS18,VPS45
GO:0060419	heart growth	GO_HEART_GROWTH	0.495711479517163	1.5982970749443	0.021674442525991	0.255274413325715	23	AGT,NDRG4,BMP10,SMAD1,PRKAR1A,AGTR2,S1PR1,NKX2-5,RXRA,TGFBR3,FOXC2,MYOCD
GO:0051340	regulation of ligase activity	GO_REGULATION_OF_LIGASE_ACTIVITY	0.307587078729911	1.40200246472648	0.0216899828315967	0.255274413325715	122	TFIP11,DCUN1D2,PCID2,CDC26,FBXW7,PSMD11,PIN1,PSMD2,UBE2N,PSMC6,MAD2L1,GOLGA2,PINK1,FZR1,BTRC,PTEN,ANAPC1,PSMC5,PSMB7,LIMK1,PSME4,GORASP1,ANAPC11,PSMA8,PARK7,CDK1,PSMD8,PSMB10,TRIB3,PSMD3,PSMB1,SMAD7,PSMA5,TPR,PSMB9,CDC20B
GO:0032102	negative regulation of response to external stimulus	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	-0.248168464428392	-1.29972419277234	0.0220092945538092	0.258129914523072	248	SEMA3F,VTN,SMPDL3B,SEMA3C,PTGIS,TYRO3,TARBP2,TRAF3IP1,WNT5A,PTPN2,HTRA1,GATA3,SCFD1,FOXF1,C1QTNF1,ANXA5,SERPING1,RPS19,TSPO,SEMA3A,SEMA3B,ANXA2,KLF4,NLRP6,CNR2,SLC6A3,F2,ROBO2,PLAUR,SAA1,TNFRSF1A,ADAMTS18,ADIPOQ,MMP28,LEP,SEMA3D,MMP26,CERS2,TRIM38,NOV,PPARG,SERPINB2,GRID2,NR1H3,PROS1,PGLYRP1,MTM1,HGF,C5,MVK,NLRP3,NLRP12,CD34,SEMA3E,ADCYAP1,THBS1,SEMA4B,CARTPT,CASK,CLN3,DEFB114,ABAT,IL2RA,SEMA4A,EDN1,ELANE,PTGER4,TRIB1,NENF,SOCS3,IL20RB,CD276,CUEDC2,UBQLN1,SERPINF1,SERPINC1,IL10,FGF2,WNT3,THBD
GO:0006721	terpenoid metabolic process	GO_TERPENOID_METABOLIC_PROCESS	-0.315249046167298	-1.4221684364846	0.0222684015396604	0.260089127363055	92	RBP4,APOA2,LRP2,AGRN,CYP26B1,RDH10,LRAT,GPC5,CYP2C9,CYP26A1,SDC1,ALDH3A2,AKR1C3,DGAT2,LPL,STAR,OPN1LW,RDH8,LRP8,RBP1,RDH13,RARRES2,APOM,CYP1A2,RETSAT,LRP1,PECR
GO:0048546	digestive tract morphogenesis	GO_DIGESTIVE_TRACT_MORPHOGENESIS	-0.383800129371423	-1.51627596180321	0.0223308846725855	0.260089127363055	47	BMP4,WNT5A,SFRP2,FGFR2,BBS7,FOXF1,SOX11,CTNNB1,EGFR,HIF1A,SMAD2,NKX2-3,STX2,ACVR2B,NODAL,STRA6,BCL2
GO:0033119	negative regulation of rna splicing	GO_NEGATIVE_REGULATION_OF_RNA_SPLICING	0.494352126649042	1.59391418327705	0.022427537562911	0.260314108402615	23	AKT2,C1QBP,ACIN1,SRSF4,SFSWAP,HNRNPA2B1,RNPS1,RBM42,DYRK1A,SRSF12
GO:0014015	positive regulation of gliogenesis	GO_POSITIVE_REGULATION_OF_GLIOGENESIS	-0.388412437849284	-1.51939562178062	0.0226295287203621	0.261755992002539	45	UFL1,NKX6-1,SPINT1,BMP2,PRKCI,TSPO,PRMT5,CLCF1,TP73,IL6ST,CSF1,MAG,PPARG,RNF112
GO:0051497	negative regulation of stress fiber assembly	GO_NEGATIVE_REGULATION_OF_STRESS_FIBER_ASSEMBLY	0.565801374127531	1.62581184633893	0.0228628784921653	0.263264969051246	15	CLASP1,DLC1,ARAP1,PPP1R9A,S1PR1,PPFIA1,TMEFF2,TACSTD2,CLASP2
GO:0032461	positive regulation of protein oligomerization	GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION	-0.54247433462808	-1.62999886836395	0.0229885057471264	0.263264969051246	16	MMP1,BBC3,SH3GLB1,FAS,BAX
GO:0051294	establishment of spindle orientation	GO_ESTABLISHMENT_OF_SPINDLE_ORIENTATION	0.479559791860094	1.5788560031566	0.0229946229652603	0.263264969051246	25	NDE1,SPAG5,CLASP1,CENPA,PAFAH1B1,ARHGEF2,EYA1,GPSM2,MAP4,PAX6,HTT
GO:0043297	apical junction assembly	GO_APICAL_JUNCTION_ASSEMBLY	-0.414915537474565	-1.54222711429871	0.0232858702676204	0.264739462026762	36	CLDN1,PARD6B,OCLN,GRHL2,PRKCI,MPP7,MARVELD2,DLG5,RAB13,MPP5,FBF1,F11R,RHOA,DLG1
GO:0060231	mesenchymal to epithelial transition	GO_MESENCHYMAL_TO_EPITHELIAL_TRANSITION	-0.555564079158955	-1.63667357132423	0.0232885310477675	0.264739462026762	15	PAX8,WT1,BMP4,GATA3,GDNF,BASP1
GO:0022600	digestive system process	GO_DIGESTIVE_SYSTEM_PROCESS	-0.355536067631401	-1.47419696062493	0.023359364296479	0.264739462026762	59	GCNT3,SERPINA3,MUC2,NMU,RBP4,EZR,AQP1,NPC1L1,MUC6,TJP2,LEP,TLR9,KCNN4,FABP1,F11R
GO:0042572	retinol metabolic process	GO_RETINOL_METABOLIC_PROCESS	-0.480955923886333	-1.59524597589429	0.0234635645302897	0.265028047681058	23	RBP4,RDH10,LRAT,AKR1C3,DGAT2,RDH8,RDH13,RETSAT,PLB1
GO:0030111	regulation of wnt signaling pathway	GO_REGULATION_OF_WNT_SIGNALING_PATHWAY	0.253625313781769	1.29478059199977	0.0236611707566462	0.266366223300572	290	LRP5,RAPGEF1,TRPM4,BIRC8,CXXC4,PRICKLE1,TMEM88,CSNK2A1,LRP6,DVL2,RNF213,PSMD11,DIXDC1,TIAM1,PPP2R3A,LRRK2,GRB10,PIN1,CCND1,PSMD2,PSMC6,RNF220,TSC2,ZRANB1,YAP1,ZEB2,CDH2,MACF1,SOX2,BTRC,WIF1,GSK3B,DKK3,CHD8,AES,RGS20,PSMC5,TCF7L1,PSMB7,MED12,NFATC4,PSME4,UBR5,LATS1,SHH,GPRC5B,ANKRD6,FOXO1,DAPK3,NKX2-5,EMD,ZNRF3,CTNNBIP1,PSMA8,FZD6,SOX17,DKK4,PSMD8,PSMB10,APC,LIMD1,SOX9,WNT11,PSMD3,PSMB1,KANK1,CSNK1A1,NFKB1,MDFI,SMAD3,SOX7,LGR5,LRRK1,PSMA5,MLLT3,PSMB9,G3BP1,BAMBI
GO:0033630	positive regulation of cell adhesion mediated by integrin	GO_POSITIVE_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN	-0.540517030382572	-1.62411766163846	0.0241141199644999	0.270560426001688	16	SFRP2,CCL21,PIEZO1,ADAM9,RET,PODXL,ZAP70,PTPN6
GO:0050728	negative regulation of inflammatory response	GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE	-0.317759239796661	-1.41958255334263	0.0244600938967136	0.272179138657901	87	SMPDL3B,PTGIS,TYRO3,PTPN2,GATA3,FOXF1,RPS19,KLF4,NLRP6,CNR2,SAA1,TNFRSF1A,ADIPOQ,MMP26,NOV,PPARG,NR1H3,PGLYRP1,HGF,MVK,NLRP3,NLRP12,ADCYAP1,IL2RA,ELANE,PTGER4,SOCS3,IL20RB,CD276,CUEDC2,SERPINF1,SERPINC1,IL10
GO:0002573	myeloid leukocyte differentiation	GO_MYELOID_LEUKOCYTE_DIFFERENTIATION	-0.313184138777901	-1.41285311531499	0.0244645429428295	0.272179138657901	92	TNFSF11,CCL19,KDM1A,BMP4,GATA3,BATF3,ANXA2,PRTN3,CTNNB1,CEBPA,CSF1,SNX10,SH3PXD2A,L3MBTL3,IRF4,TNFSF9,MT1G,PPARG,NKX2-3,EPHA2,NKAP,JUNB,IL25,OSTM1,CDC42,FAM20C,CEBPE,IFI16,SIRT1,PSEN1
GO:0061384	heart trabecula morphogenesis	GO_HEART_TRABECULA_MORPHOGENESIS	0.484084343730582	1.57740237422827	0.0245009741572621	0.272179138657901	24	UBE4B,BMP10,NACA,CAV3,EGLN1,DLL4,S1PR1,NKX2-5,TEK,FHL2,HEY2,MED1,SRF,TGFBR3
GO:0033539	fatty acid beta oxidation using acyl coa dehydrogenase	GO_FATTY_ACID_BETA_OXIDATION_USING_ACYL_COA_DEHYDROGENASE	0.539532509816245	1.602795521018	0.0246615087040619	0.27306131019037	17	IVD,ACOX3,ACAD9,ACADM,ACAD10,ETFA,GCDH,ACADVL
GO:0061001	regulation of dendritic spine morphogenesis	GO_REGULATION_OF_DENDRITIC_SPINE_MORPHOGENESIS	0.455587555754717	1.55707881572519	0.0248234070126125	0.273098083693029	29	SHANK3,NLGN3,PAFAH1B1,TIAM1,LRRK2,PTEN,CFL1,PPP1R9A,DNM3,CAMK2B,EPHA4,BHLHB9,MARCKS,ITPKA
GO:0048278	vesicle docking	GO_VESICLE_DOCKING	-0.366560093535618	-1.48589007632893	0.0248864668483197	0.273098083693029	53	CFTR,STX19,SNAP25,SCFD1,EXOC5,STXBP3,RAB13,STX11,VPS33A,UNC13B,KCNB1,STX2,STXBP1,VPS18,VPS45,STX12,TSNARE1
GO:1903509	liposaccharide metabolic process	GO_LIPOSACCHARIDE_METABOLIC_PROCESS	-0.302972093881083	-1.39669124913932	0.0249082328264289	0.273098083693029	104	GAL3ST1,SMPD3,ARSF,PIGV,ARSH,ITGB8,PIGW,B3GNT5,POGLUT1,PIGX,SMPD2,PLAUR,GAL3ST2,ARSI,ARSD,GAL3ST4,PIGU,NEU1,NEU2,ST3GAL5,PIGZ,BAX,ARSK,CLN3,NANS,PIGF,KDELC2,ARSE,PIGQ,PIGK,UGT8,GBA3
GO:0060669	embryonic placenta morphogenesis	GO_EMBRYONIC_PLACENTA_MORPHOGENESIS	-0.492174931580008	-1.59339913202057	0.0253606582422139	0.277155765075624	21	SPINT1,GRHL2,FGFR2,CYR61,WNT7B,ST14
GO:0002068	glandular epithelial cell development	GO_GLANDULAR_EPITHELIAL_CELL_DEVELOPMENT	-0.526096563860307	-1.60896334529729	0.0256088592810486	0.278962525372199	17	NKX6-1,RARA,BMP4,WNT5A,BMP5,PDPK1,INSM1
GO:0071826	ribonucleoprotein complex subunit organization	GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION	0.282036493578837	1.34799651062903	0.0257541453019911	0.279640171246781	170	TFIP11,SF3A2,ADAR,DDX3X,ERAL1,NPM1,C1QBP,RPL3L,MDN1,PRMT7,TDRD5,SBDS,PRPF6,MRTO4,KIF5B,SNRNP200,PRPF3,DYNC1H1,FASTKD2,ABT1,CELF1,MTIF3,SCAF11,CLP1,DDX39B,PRPF39,LUC7L,SFSWAP,MRPL20,SETX,EDC3,LSM4,HBS1L,DHX30,XAB2,SMN1,PRPF31,RPS14,SRSF1,LIMD1,SNRPC,PRPF19,DICER1,PLD6,ZNHIT6,EIF3J,PATL1,CD2BP2,SF1,ATXN2L,DDX20,RRP7A,RBM5,KLC1,NSUN4,DDX23,RPL10,EIF3D,MPV17L2,WDR77,PRPF8,MRRF
GO:0060349	bone morphogenesis	GO_BONE_MORPHOGENESIS	-0.326121450041572	-1.42816762623402	0.0258405759955262	0.279676459167014	78	MATN1,NAB2,RARA,CYP26B1,BMP4,SFRP2,ALPL,T,THBS3,SERPINH1,FGFR2,PAPPA2,COMP,FGF18,BMPR1B,MSX2,FGF4
GO:0045807	positive regulation of endocytosis	GO_POSITIVE_REGULATION_OF_ENDOCYTOSIS	-0.29889117656591	-1.3878481142552	0.025923790303205	0.27967781461727	109	VTN,C3,C4A,C2,CCL19,NLGN1,WNT5A,ANO6,ANGPT1,LMAN2,SNCA,CALR,TOR1A,CALY,PYCARD,CCL21,TULP1,DAB2,ABCA7,PPARG,MAGI2,PROS1,MBL2,PICK1
GO:0042692	muscle cell differentiation	GO_MUSCLE_CELL_DIFFERENTIATION	0.266381779676731	1.31698445099514	0.0261967368403861	0.281719540590222	221	XK,AGT,FBXO40,OBSCN,EPAS1,ITGA8,ANK2,DNER,TBX2,LDB3,CFLAR,SGCD,SGCG,TSC1,CACNA2D2,CAPN3,BMP10,MKL2,CDH2,BARX2,QKI,LMOD1,LMOD3,HMGCR,MKL1,GSK3B,SMARCD3,CAV3,OBSL1,REST,TMEM204,TCAP,DMD,PRKAR1A,SLC8A1,AKAP13,AGTR2,NFATC4,MYPN,TTN,KAT2A,DYRK1B,SIX1,SHH,TMOD1,MYL2,MTOR,TBX5,NKX2-5,FLNC,FHL2,RXRA,CDK1,VEGFA,HOMER1,FHOD3,SOX9,MYLK3,TANC1,HEY2,SORT1,LRRC10,TMEM8C,FGF6,CFL2,CSRP2,ATP2A2,ASF1A,PROX1,TBX3,ADM,NOX4,MEF2C,SRF,PLEKHO1,SGCB,PTCD2,P2RX2,CASQ2,ACTN2,SMO,IGFBP5,RARB,MYOCD
GO:0006414	translational elongation	GO_TRANSLATIONAL_ELONGATION	0.317860055655357	1.40317192535419	0.0264125537314206	0.28174359083815	101	PTCD3,AURKAIP1,GFM1,MRPL4,MRPL16,EEF1A2,MRPL41,MRPL14,MRPL19,MRPS15,MRPL53,MRPL15,MRPL27,MRPS28,MRPL24,MRPL35,MRPL20,MRPL17,MRPL12,HBS1L,MRPL37,MRPL51,MRPS22,MRPS18B,MRPL39,MRPS25,EEFSEC,MRPL46,MRPL18,MRPS30,DIO2,MRPS17,MRPL28,SEPSECS,MRPL30,MRPS7,MRPL54,MRPS26,EEF1D,MRPL10,MRPL52
GO:0060441	epithelial tube branching involved in lung morphogenesis	GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS	-0.46117738730145	-1.56437124608759	0.0264551427127508	0.28174359083815	25	RDH10,BMP4,KRAS,FGFR2,FOXF1,FOXA1,CTNNB1,DLG5,RSPO2
GO:0030239	myofibril assembly	GO_MYOFIBRIL_ASSEMBLY	0.393387842843686	1.49473415835259	0.0264917325664989	0.28174359083815	46	OBSCN,LDB3,CFLAR,CAPN3,BMP10,LMOD1,LMOD3,OBSL1,TCAP,PRKAR1A,MYPN,TTN,TMOD1,MYL2,NKX2-5,FHOD3,MYLK3,CFL2,PROX1,SRF,CASQ2,ACTN2,NEBL,CSRP3
GO:0002026	regulation of the force of heart contraction	GO_REGULATION_OF_THE_FORCE_OF_HEART_CONTRACTION	0.457510772604705	1.55024349317704	0.0265337844015726	0.28174359083815	28	ADRB1,ADRB2,RYR2,ATP1A2,PLN,SLC8A1,MYH7,MYL2,ATP2A2,MYL4,ADM,CSRP3,GLRX3,CAMK2D,NOS3,APLN
GO:0010719	negative regulation of epithelial to mesenchymal transition	GO_NEGATIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	-0.497939327828394	-1.59119629365935	0.026630694921892	0.281883393418517	20	VASN,SFRP2,FOXA1,TRIM62,BMP5
NA	positive regulation of tyrosine phosphorylation of stat5 protein	GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT5_PROTEIN	0.543814361123488	1.58899022850073	0.0273022953257132	0.287787087070203	16	JAK2,GH1,ERBB4,IL4,CSF2,IL2
GO:0032370	positive regulation of lipid transport	GO_POSITIVE_REGULATION_OF_LIPID_TRANSPORT	-0.372073451058067	-1.48368408923723	0.0274015819005341	0.287787087070203	49	TNFSF11,LRAT,RETN,C1QTNF1,ADIPOQ,ABCA7,ABCA1,PLTP,NR1H3,PRELID1,CYP4F2,GAL,ABCG1,TRIAP1,LRP1,TMF1,MIF,EDN1
GO:0044782	cilium organization	GO_CILIUM_ORGANIZATION	-0.269746977459373	-1.32915799159247	0.027444936110973	0.287787087070203	159	C5orf42,CNGB1,TRAF3IP1,IQCB1,C11orf63,IFT57,RFX4,WDR35,BBS7,SSX2IP,KIF3A,CCDC114,ATP6V0D1,TTLL1,WDR19,SNX10,RFX2,B9D2,DNAH1,TTC30B,SPEF2,DZIP1L,DYNC2LI1,ONECUT1,CEP89,PCM1,TTC26,DYNLL1,IFT20,CEP41,ARL13B,E2F4,FBF1,CCDC13,TMEM231,RAB17,RP1L1,KIAA0586,TTC8,AKAP4,FAM161A,BBS10,DNAH5,RAB23,LRRC6,ABCC4,DYNC2H1,CLUAP1,HSPB11,RSG1,IFT140,SEPT2,EHD3,KIF24,TMEM237,TCTN2
GO:0046165	alcohol biosynthetic process	GO_ALCOHOL_BIOSYNTHETIC_PROCESS	0.31254883937772	1.39362887770522	0.027597932301774	0.288053420816224	107	IDI2,CNBP,CHAT,LSS,LPIN1,PCYT1A,CHPT1,LCAT,PLA2G5,HMGCR,IMPA2,MVD,CYP27B1,CYP51A1,PRKAA2,ACER2,CYB5R1,IP6K3,GGPS1,MSMO1,IPMK,INSIG1,PCYT1B,HMGCS2,PARK7,HMGCS1,SQLE,GOT1,PTAFR,CYP3A4,IDI1,SGMS1,FDFT1,SLC27A1,CHKA,SCP2,NSDHL,APOA5,HSD17B3
GO:0008213	protein alkylation	GO_PROTEIN_ALKYLATION	0.318547691165669	1.4018746629247	0.0276414898763043	0.288053420816224	99	WDR82,RAB6A,PRDM2,PRMT7,DYDC1,PCMTD2,SUV39H1,EED,NSD1,WHSC1L1,PCMTD1,SETDB1,FBXO11,SMYD1,EZH2,EZH1,METTL21C,CAMKMT,TET2,METTL21A,RBBP5,SETD7,SETD1B,MECOM,CTCFL,PRDM9,SETDB2
GO:0098840	protein transport along microtubule	GO_PROTEIN_TRANSPORT_ALONG_MICROTUBULE	-0.45374285184946	-1.55521215602493	0.0279128082176715	0.288200412853266	26	TRAF3IP1,IFT57,WDR35,SSX2IP,WDR19,TTC30B,PCM1,TTC26,DYNLL1,IFT20
NA	macromolecular complex disassembly	GO_MACROMOLECULAR_COMPLEX_DISASSEMBLY	0.279175925196199	1.33743826545859	0.0280064527931614	0.288200412853266	173	TFIP11,SMARCB1,LRP5,PTCD3,AURKAIP1,MRPL4,MRPL16,LRP6,DVL2,MRPL41,VPS4A,MRPL14,KIF5B,MICAL3,MRPL19,MRPS15,APEH,MRPL53,HMGA1,PEX14,GSK3B,SMARCD3,CHMP7,MTIF3,CFL1,MRPL15,MRPL27,MRPS28,HIST1H2BA,MRPL24,MRPL35,WNT8B,MRPL20,MRPL17,MRPL12,HBS1L,MRPL37,MRPL51,HDAC6,APC,MRPS22,CSNK1A1,MRPS18B,MRPL39,CFL2,MRPS25,MRPL46,GSPT1,KLC1,MRPL18,DDIT4,KIF19,MRPS30,MRRF,CHMP1B,MRPS17,MRPL28,SYNJ1,NAPB,MRPL30,MRPS7,MRPL54,NAPA,MRPS26,MCTS1
GO:0007597	blood coagulation intrinsic pathway	GO_BLOOD_COAGULATION_INTRINSIC_PATHWAY	0.533873850193711	1.58598527486425	0.0280836185091504	0.288200412853266	17	KLKB1,VWF,C1QBP,F8
GO:0006911	phagocytosis engulfment	GO_PHAGOCYTOSIS_ENGULFMENT	-0.441089215692308	-1.54106973282122	0.0281572036983913	0.288200412853266	28	IGHG4,IGHG2,IGHG1,ABCA1,IGHD,THBS1,IGKC,IGLL1,IGLC1,RAC1,IGHA1,DOCK1,MYH9,VAMP7,FCGR1A,IGLL5
GO:0046661	male sex differentiation	GO_MALE_SEX_DIFFERENTIATION	-0.279161638849473	-1.34540765353138	0.0282041865589423	0.288200412853266	137	LHX9,KIF18A,AMHR2,RARA,WT1,TGFBR1,WNT5A,SFRP2,NUPR1,WNT2B,MGST1,GATA3,DMRT1,FSHR,SDC1,ADAM15,UTF1,INSL3,SGPL1,REC8,CTNNB1,BOK,AKR1C3,STAR,RAB13,BMP5,COL9A3,FGF9,MEA1,PRKACG,SOX15,BAX,HMGB2,HSD17B10,WNT9B,TMF1,FSHB
GO:0090185	negative regulation of kidney development	GO_NEGATIVE_REGULATION_OF_KIDNEY_DEVELOPMENT	-0.521212853157927	-1.5940274722106	0.0282043517757494	0.288200412853266	17	PAX8,OSR1,WT1,BMP4,GATA3,CTNNB1,ADIPOQ
GO:0072522	purine containing compound biosynthetic process	GO_PURINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	0.302685133846601	1.37600345357801	0.0282776349614396	0.288200412853266	120	ATP5L,PANK3,CECR1,GUCY1A2,GMPR,AK1,PPAT,GUCY1B3,ATP5A1,ATP5G2,ATP5D,OAS2,GUCY1A3,COASY,AK4,ADCY7,NPR2,ATP5O,ADCY5,ATP5B,NME6,ADA,ATP5G3,GUCY2C,ADCY8,ADCY9,OAS1,ADSSL1,PANK4,ADCY4
GO:0045667	regulation of osteoblast differentiation	GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION	-0.299602001436039	-1.38115523535505	0.0283405634742814	0.288200412853266	104	PRKD1,ID4,AREG,BMP4,SFRP2,BMP2,NPNT,CEBPB,FGFR2,CYR61,SOX11,GDF10,ACVR1,MEN1,WNT10B,CTNNB1,BMPR1B,TOB1,IL6ST,CEBPA,OSTN,MSX2,WNT7B
GO:0035994	response to muscle stretch	GO_RESPONSE_TO_MUSCLE_STRETCH	0.514739310285962	1.57516267261377	0.0284448891853828	0.288270431314131	19	RYR2,CAV3,TCAP,DMD,SLC8A1,TTN,RAF1,NFKB1,NFKBIA
GO:0051896	regulation of protein kinase b signaling	GO_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING	-0.294048162775071	-1.37413358830685	0.0285638592519448	0.288270431314131	113	CHI3L1,CCL3,TNFSF11,CCL19,KIAA1161,PHLDA3,TGFBR1,FAM110C,ANGPT1,GATA3,C1QTNF1,ITGB1BP1,KLF4,F7,CCL21,HPSE,AKR1C3,MST1R,EGFR,MSTN,LEP,STK3,TNFAIP8L3,MAGI2,MTM1,INPP5K,THBS1,EPHA2,PHLPP1,OSBPL8,SFRP5,DLG1,F3,LMBRD1,SIRT1,BANK1,RICTOR,NRG1
GO:0014850	response to muscle activity	GO_RESPONSE_TO_MUSCLE_ACTIVITY	0.532991760799561	1.58336484161073	0.0286043743490552	0.288270431314131	17	AGT,AKT2,RYR2,CAPN3,PRKAA2,SRL,ADSSL1
GO:0044803	multi organism membrane organization	GO_MULTI_ORGANISM_MEMBRANE_ORGANIZATION	0.46444615501587	1.54438282124154	0.0290984433157924	0.291773935605236	26	LRSAM1,VPS4A,CHMP7,VPS37B,MITD1,VPS37C,HYAL2,CHMP6,TSG101,VPS37A,CHMP1B,CD4,CHMP4B,CCR5,CHMP4C
GO:0051962	positive regulation of nervous system development	GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT	-0.221814652121063	-1.2254774218235	0.0291789187966523	0.291773935605236	404	GDF5,BEND6,HAP1,TCF3,LRRN1,CNR1,SLITRK2,SYT4,ITGA3,UFL1,NKX6-1,NLGN1,AGRN,RARA,SPINT1,FLRT3,CDON,SNW1,GDPD5,PRKD1,BMP4,WNT5A,CUL7,BMP2,MMD,KATNB1,SLITRK4,NEUROG1,LRRC4B,PTK7,PRKCI,SYT17,MAP2K2,EFNA5,LPAR1,CBLN2,SGK1,FOXA1,SOX11,TPBG,TLE6,SKIL,TSPO,OPRM1,SEMA3A,PRMT5,CLCF1,LHX5,FLRT2,SRPX2,PLXNB2,COBL,CTNNB1,TP73,FEZF1,IL6ST,CSF1,FLRT1,STAR,HIF1A,CLSTN3,ROBO2,BAIAP2,LRP8,BMP5,FZD3,MAG,DUOXA1,INPP5E,DPYSL3,KCTD11,PPARG,RND2,NEU1,CDH4,MAGI2,PAK3,AMIGO2,LTK,SEZ6,RNF112,HGF,CPNE6
GO:0046031	adp metabolic process	GO_ADP_METABOLIC_PROCESS	0.398245455900689	1.49184360301224	0.0292120666366502	0.291773935605236	43	BAD,OGDHL,AK1,PGAM2,PGAM1,OGDH,DHTKD1,AK4,PFKM,GCK,PFKFB4,PFKP,ALDOC,ALDOA,HK3,ENO2,GALK1
NA	negative regulation of protein complex assembly	GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY	0.315945787799081	1.39288798623193	0.0293889243619169	0.292555545396361	100	TFIP11,SPTB,DDX3X,TMC8,PYDC2,TBCD,ULK1,XAF1,LMOD1,LMOD3,INPP5J,PEX14,ADD1,GSK3B,VDAC2,RAF1,CAPZB,MEFV,PRKCZ,TMOD1,INSIG1,TBX20,CTNNBIP1,PARK7,ARFGEF1,FHOD3,HEY2,IMPACT,RDX,MKKS,KANK1,HMGB1
GO:0031047	gene silencing by rna	GO_GENE_SILENCING_BY_RNA	0.304866491446856	1.37592364441339	0.0295231919178129	0.292555545396361	115	ADAR,METTL3,POM121,WTIP,NCBP1,TNRC6C,ZCCHC11,NUP85,HIST1H3G,SMAD1,HIST1H3B,TNRC6A,RAE1,HENMT1,CELF1,HIST1H4F,CLP1,CNOT6L,LIN28B,H3F3A,POLR2I,NUP188,TNRC6B,NCBP2,SRRT,IPO8,HNRNPA2B1,LIMD1,MOV10,DICER1,HIST1H3E,TDRKH,CNOT8,SMAD3,TSN,TPR,AAAS,POLR2C,POM121C,CNOT1
GO:0006007	glucose catabolic process	GO_GLUCOSE_CATABOLIC_PROCESS	0.452878664023241	1.53454791480362	0.0295510651915516	0.292555545396361	28	LRP5,BAD,PGAM2,PGAM1,PFKM,GCK,PFKFB4,PFKP,ALDOC,ALDOA,HK3,ENO2
GO:0002250	adaptive immune response	GO_ADAPTIVE_IMMUNE_RESPONSE	-0.243118669982864	-1.27327707740457	0.0296590256383479	0.292763285333369	248	RAET1E,GCNT3,C3,CD55,C4A,C2,CD7,CFI,IL18,C9,C4BPA,TNFRSF21,GATA3,MASP2,CD79B,HLA-DRB5,C1RL,SERPING1,C1R,ANXA1,FCRL4,C1S,C4BPB,RIPK2,IFNA14,EXOSC6,IRF7,IRF4,TFE3,IGHG4,LILRB2,IGHG2,LILRA4,IGHG1,ORAI1,IFNE,RAG1,EIF2AK4,LAT,MBL2,FAS,C5,IGHD,IFNA16,BTLA,IGKC,LILRB5,TXK,RNF8,POU2F2,SEMA4A,IGLL1,UNC93B1,IGLC1,VTCN1,HLA-DRB1,CD1A,DLG1,GNL1,NBN,SWAP70,IL4R,CD46
GO:2000351	regulation of endothelial cell apoptotic process	GO_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS	-0.394451155868521	-1.49359187092325	0.0301741505126024	0.296977165571403	39	SCG2,KDR,BMP4,ANO6,ANGPT1,GATA3,PRKCI,XBP1,AKR1C3,ANGPTL4
GO:0034248	regulation of cellular amide metabolic process	GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS	0.247364435572201	1.27067508754801	0.0303261977573904	0.297603445047744	308	LSM14B,CPEB3,TRAP1,PTCD3,LARP4B,ADAR,METTL3,DDX3X,AKT2,EIF2B5,WTIP,NPM1,MKNK1,C1QBP,PRR16,NCBP1,BARHL2,APP,RMND1,PAIP2B,TNRC6C,ZCCHC11,ESR1,SAMD4A,TSC1,CPEB2,NSMAF,TACO1,PGAM2,PGAM1,SMAD1,MIF4GD,QKI,PINK1,TNRC6A,LARS2,FAM129A,CELF1,UCN,DDX39B,MTG1,CNOT6L,LIN28B,ABCF1,IARS2,UNK,MAPKAPK5,TIA1,KHDRBS1,EP300,PAIP2,TNRC6B,EIF4E2,MTOR,YTHDF2,DAPK3,NCBP2,TNF,SRRT,RXRA,NCOR1,RPS14,MAPK1,HNRNPA2B1,LIMD1,MOV10,DICER1,HSPB1,EIF3J,CNOT8,METAP1,EIF1B,LRRTM3,IMPACT,EIF2B4,PTAFR,SMAD3,PASK,IMP3,GIGYF2,TPR,EIF4E3,EEFSEC,EIF4G1,RBM8A,EIF2AK1,CNOT1,NSUN4
GO:0072207	metanephric epithelium development	GO_METANEPHRIC_EPITHELIUM_DEVELOPMENT	-0.490832208500069	-1.56848504893171	0.0304381880684043	0.297834130925142	20	PAX8,OSR1,WT1,UMOD,POU3F3,WNT7B,WNT9B,PKD2
GO:0055007	cardiac muscle cell differentiation	GO_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	0.344180143488515	1.42886082197739	0.0310462698664411	0.302903606870843	71	AGT,TSC1,BMP10,CAV3,OBSL1,TCAP,SLC8A1,AKAP13,AGTR2,TTN,KAT2A,MYL2,MTOR,TBX5,NKX2-5,FHL2,RXRA,CDK1,VEGFA,FHOD3,MYLK3,HEY2,LRRC10,PROX1,TBX3,NOX4,MEF2C,SRF,SGCB,ACTN2,RARB,MYOCD,NEBL,CSRP3
GO:0007220	notch receptor processing	GO_NOTCH_RECEPTOR_PROCESSING	0.550100914691354	1.58069708679339	0.0313016970575661	0.302988039484663	15	DNER,NOTCH3,NCSTN,PSENEN,DLL4,ADAM10,APH1A,PSEN2
GO:0051051	negative regulation of transport	GO_NEGATIVE_REGULATION_OF_TRANSPORT	0.233834091231146	1.23907904521841	0.0313834955199482	0.302988039484663	416	P2RY1,AGT,LRSAM1,LRRTM2,RSAD2,BMP8A,IL1RAPL1,GPM6B,OPRL1,AKT2,BEST3,PYDC2,DLG4,PDE8B,DRD4,VIP,NPY1R,UNC119,LRRK2,CALM3,GRB10,AKAP1,ITGB3,ESR1,RANGAP1,APOC3,WNK1,NEDD4L,ATP1A2,LGALS3,DRD2,OPRK1,GHSR,CEACAM1,ADRA2C,PACSIN2,PPIF,PCSK9,SP100,ABR,SERGEF,HMGCR,OSM,SUFU,PKIA,PDE4C,GSK3B,CAV3,PTEN,REST,SIAH3,SIRT4,CABP1,UCN,PLN,CD300A,IRS1,GCK,PPP1R9A,PLCB4,AGTR2,KCNH2,PDE2A,TBC1D4,DERL3,HADH,SLC26A5,SHH,CX3CL1,CALM1,ADA,HAMP,MTOR,INSIG1,KCNA5,GBP1,CCR2,YOD1,TNF,GABBR1,NPY5R,EMD,KCNRG,SEMG1,PARK7,GRK6,BAG4,FAF1,ANK3,IL11,MAOB,CRHBP,NFKB1,SLC30A1,MDFI,HMGB1,ENY2,GNAO1,CD36,FGF12,TRDN,OAZ1,SUMO1,TPR,NPFF,LILRB1,STXBP6,PRKCE,LITAF,NFKBIA,TNFSF4,ARF6,COMMD1,EGF,CSN2
GO:0019079	viral genome replication	GO_VIRAL_GENOME_REPLICATION	0.510175849282894	1.56119794661301	0.0313912979023052	0.302988039484663	19	SMARCB1,ATG16L1,PCBP2,VCP,HTATSF1,ATG16L2,NFIA,PCBP1
GO:0019058	viral life cycle	GO_VIRAL_LIFE_CYCLE	-0.242149359378674	-1.2686091222035	0.0314149809210182	0.302988039484663	249	CLDN1,RPL24,CD55,RPL38,TYRO3,DPP4,EFNB3,NMT2,WWP2,RPL35,RPL30,HAVCR1,RPL9,SLC10A1,RPL3,RPS3A,ANPEP,RPS19,RPS27,PC,RPL4,RPS11,RPL7A,RPS4Y1,RPS8,EIF3L,RPL18,KPNA7,THOC6,RPS24,RPL18A,UBA52,RPL15,RPS16,RPL5,VAMP8,RPL10A,RPS3,NUP50,CLEC5A,RPL22,SELPLG,EIF2AK4,RPS29,RPL26,RPL19,CHMP5,RPS28,F11R,RPS5,RPS17,VTA1,VPS18,HLA-DRB1,UBB,RPL36,THOC7,RPS6,CD46,RPL23A,EIF3G,RPS18,HTR2A,FAU,RPL32,PTBP1,CD81,RPLP0,RPL14,NUP210,RPS15,FURIN,RAN,SEH1L,DYNLT1,RPS13,RPL28,RPS4X,DERL1,RPL34,KPNA1,APOE
GO:0048025	negative regulation of mrna splicing via spliceosome	GO_NEGATIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME	0.509913700784217	1.5603957414549	0.031539544881773	0.30332030877728	19	C1QBP,ACIN1,SRSF4,SFSWAP,HNRNPA2B1,RNPS1,RBM42,DYRK1A,SRSF12
GO:0002009	morphogenesis of an epithelium	GO_MORPHOGENESIS_OF_AN_EPITHELIUM	-0.222534930072886	-1.22370348249416	0.0318919976521229	0.305836080048563	384	C5orf42,SEMA3C,WNT6,EZR,KRT71,PAX8,OSR1,TRAF3IP1,RARA,SPINT1,CA9,WT1,FLRT3,RDH10,IFT57,ID4,AREG,BMP4,WNT5A,SFRP2,BMP2,MET,T,NPNT,FGF7,KRAS,GATA3,PTK7,GRHL2,FGFR2,BBS7,TMED2,FOXF1,FOXA1,CYR61,SOX11,MTHFD1L,GBX2,SEMA3A,ACVR1,RIPK4,PLXNB2,KLF4,COBL,KRT25,CTNNB1,TOR1A,MMP12,DLG5,CSF1,EGFR,TMEM79,MSX2,WNT7B,HIF1A,ST14,RAB10,FZD3,MPP5,STK3,ZIC3,RSPO2,IRX1,GDNF,SCNN1B,IFT52,TIMELESS,SEMA3E,ARL13B,BAX,KRT16,EPHA2,MSN,RALA,WNT9B,TULP3,PPP1CA,PKD2,RHOA,SALL4,NODAL,LMO4,GNA13,MYC,EDN1,STIL,CDC42,TBX4,MYCN,DLG1,ADAMTS16,IRX2,AXIN1,SOCS3,PSEN1,RET,HOXB13,PODXL,FRAS1,IL10,MMP14,BCL2,FGF2,PDCD10,WNT7A,RHOC,DDR1,PLXNA1,NOG
GO:0035148	tube formation	GO_TUBE_FORMATION	-0.282131899077485	-1.34237786028535	0.0321311635635049	0.306291686475176	127	WNT6,PAX8,OSR1,RARA,SPINT1,IFT57,BMP4,WNT5A,SFRP2,T,GATA3,PTK7,GRHL2,TMED2,ITGB1BP1,SOX11,MTHFD1L,PLXNB2,COBL,EDAR,CTNNB1,HIF1A,ST14,FZD3,STK3,IRX1,GDNF,IFT52,RALA,WNT9B,TULP3,SALL4,NODAL,LMO4,STIL
GO:0061337	cardiac conduction	GO_CARDIAC_CONDUCTION	0.337805556664283	1.41663431487092	0.0322013639879069	0.306291686475176	75	PRKACA,TRPM4,CACNA2D4,ANK2,CTNNA3,SCN5A,CACNA2D1,RYR2,CACNA2D2,ATP1A2,RNF207,KCNJ2,GJA1,CACNG1,PKP2,PLN,SLC8A1,KCNH2,CACNA1C,GJA5,KCNA5
GO:0070875	positive regulation of glycogen metabolic process	GO_POSITIVE_REGULATION_OF_GLYCOGEN_METABOLIC_PROCESS	0.548303924720999	1.57553349455917	0.0322124946560345	0.306291686475176	15	AKT2,IRS1,GCK,HMGB1,PTH,PHKG2,EPM2AIP1,SORBS1,INSR,DYRK2
GO:0061036	positive regulation of cartilage development	GO_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT	-0.435234349513621	-1.52061410448868	0.0323057572213518	0.306313179738226	28	GDF5,BMP4,WNT5A,BMP2,CYR61,FGF18,BMPR1B,SOX6
GO:0051653	spindle localization	GO_SPINDLE_LOCALIZATION	0.413133635922714	1.49639521820406	0.0324058149428825	0.306398800836355	37	NDE1,SPAG5,CLASP1,CENPA,PAFAH1B1,ARHGEF2,EYA1,DYNC1H1,SPIRE1,GPSM2,MAP4,WASL,PAX6,HTT,ESPL1,SPRY2,SPIRE2,KPNB1
GO:0051260	protein homooligomerization	GO_PROTEIN_HOMOOLIGOMERIZATION	-0.243504164323054	-1.2689537795456	0.0327147802097702	0.306796527722252	239	CLDN1,KCTD4,SLC34A1,P2RX1,KCNV2,TNFSF11,SHMT1,ACADL,NLGN1,TRIM72,KCNS2,COLEC12,DPYS,KCNA3,ENTPD2,SLC1A1,MGST1,C1QTNF1,ANXA5,SKIL,IMPDH2,KCNG1,EVL,CAT,TOR1A,RIPK1,SMARCAD1,TAF10,KCTD8,EIF2AK3,RIPK3,FBP1,ADIPOQ,ANGPTL4,CALHM1,DPYSL3,KCTD11,ZBTB1,RYR3,ITPR3,KCNG3,FAS,KCNB1,ATL3,KCNA1,POLQ,USP16,AQP11,BAX,HSD17B10,ATL1,NPM2,MFF,HM13,MIF,SCARA5,IKBKE,THBS4,CEP57,SPAST,KCTD1,NELL2,SYT1,TOR2A,TYSND1,ST13,TRPA1,ACACA,AKR1C1,KCTD13,TERF1,SRR,KCNG4,ALOX5AP,KCTD19,EHD3,KCNA4,KCNV1,DERL1
GO:0071353	cellular response to interleukin 4	GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_4	-0.452356324230958	-1.53444909940961	0.0327173650326295	0.306796527722252	25	GATA3,RPL3,IMPDH2,XBP1,KEAP1,IL24,MCM2,FASN
GO:0035023	regulation of rho protein signal transduction	GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION	0.3113033170396	1.37930520242398	0.0327213171278338	0.306796527722252	103	MCF2L,FLCN,OBSCN,PREX2,DLC1,TIAM1,ARHGEF12,ALS2,FGD6,APOC3,ARHGEF2,CDH2,PLEKHG2,ABR,MYO9B,RASGRF1,ARHGEF6,ARHGAP35,SPATA13,AKAP13,TRIO,ITSN2,RAF1,FARP2,ARHGDIB,SCAI,KANK1,ARHGEF37,ARHGEF10L,FGD5,ARHGEF9,BCL6
GO:0009062	fatty acid catabolic process	GO_FATTY_ACID_CATABOLIC_PROCESS	0.345481127010597	1.42726929018247	0.0329217382114108	0.307332718599202	69	SLC25A17,DECR1,IVD,PPARD,LPIN1,ACOX3,ACAD9,ACADM,MMAA,ACAD10,CEL,PLA2G15,HADH,ECI2,ETFA,PEX7,ACOT8,HADHB,PCCB,ECHS1,GCDH,ACADVL,PCCA,HADHA
GO:0009066	aspartate family amino acid metabolic process	GO_ASPARTATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS	0.377019656221475	1.45837379747941	0.0329611145021723	0.307332718599202	50	DDO,ALDH7A1,DLD,THNSL1,MTR,THNSL2,MTHFR,OGDH,ASRGL1,NMNAT3,GOT2,ADSSL1,EIF2B4,GOT1,GCDH,ASNS,SMS,DLST,NMNAT2,NIT2,PIPOX,PLOD1,CRYM,NMNAT1,ASNSD1
GO:0043647	inositol phosphate metabolic process	GO_INOSITOL_PHOSPHATE_METABOLIC_PROCESS	0.367116183511744	1.4485878809952	0.0332798001427552	0.309446981437884	55	PLCB2,NUDT4,CALM3,PLCH1,INPP5J,INPPL1,PLCE1,IMPA2,PTEN,ITPK1,INPP5D,INPP1,PLCB4,IP6K3,CALM1,IP6K2,IPMK,PLCD3,PLCG1,PTAFR,ITPKC,INPP5A,ITPKB,ITPKA,SCP2,MTMR2,ISYNA1
GO:0045686	negative regulation of glial cell differentiation	GO_NEGATIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION	-0.45698380525379	-1.53418854036576	0.033555575050443	0.31115169592229	24	DLX1,NKX6-1,ID4,BMP4,CTNNB1,F2
GO:0050774	negative regulation of dendrite morphogenesis	GO_NEGATIVE_REGULATION_OF_DENDRITE_MORPHOGENESIS	0.546094405507393	1.56918451296163	0.033811037379877	0.3123386727311	15	NLGN3,GSK3B,RAPGEF2,PTEN,NFATC4,GORASP1,DNM3
GO:1900006	positive regulation of dendrite development	GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT	0.356756758439023	1.43767523093189	0.03386916682913	0.3123386727311	61	CPEB3,SHANK3,NLGN3,CDKL5,IL1RAPL1,PAFAH1B1,TIAM1,RAB21,VLDLR,SHANK1,ARF1,OBSL1,PPP1R9A,EZH2,FBXO31,MTOR,CAMK2B,EPHA4,ZMYND8,IL2,BHLHB9,OPA1,MARCKS,ITPKA
GO:0007212	dopamine receptor signaling pathway	GO_DOPAMINE_RECEPTOR_SIGNALING_PATHWAY	0.457719210319726	1.52201429107723	0.0339940226260107	0.31263355234741	26	RGS9,GNAS,DRD4,GNG2,DRD2,GPR52,GSK3B,ADCY5
GO:0050922	negative regulation of chemotaxis	GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS	-0.370007133235923	-1.46178408730656	0.034206138176574	0.313727141968251	47	SEMA3F,SEMA3C,WNT5A,PTPN2,SEMA3A,SEMA3B,ROBO2,MMP28,SEMA3D,NOV,C5,SEMA3E,THBS1,SEMA4B,SEMA4A,ELANE
GO:0048713	regulation of oligodendrocyte differentiation	GO_REGULATION_OF_OLIGODENDROCYTE_DIFFERENTIATION	-0.438394718678897	-1.5177630763612	0.0344280711028877	0.314904585142174	27	DLX1,SLC45A3,ID4,BMP4,TNFRSF21,PRMT5,CTNNB1,TP73,PPARG
GO:0015696	ammonium transport	GO_AMMONIUM_TRANSPORT	-0.355948819695785	-1.44287615644546	0.0345821980018165	0.315457123236082	53	SCN4A,P2RX1,AQP1,SLC22A4,SNCA,SLC38A2,SLC18A1,SLC22A3,SLC6A3,SNAP23,SLC18A2,RHCE,SLC44A5,ADCYAP1,OAZ3,EDN1,FCER1A,SLC44A1,PSEN1,SLC18A3
GO:0090162	establishment of epithelial cell polarity	GO_ESTABLISHMENT_OF_EPITHELIAL_CELL_POLARITY	-0.484538749286801	-1.54837390603781	0.034876637222053	0.317283137539001	20	EZR,WNT5A,PTK7,FOXF1,FRMD4B,MPP5,FERMT1,MSN,FBF1,SIPA1L3
GO:0032259	methylation	GO_METHYLATION	0.257748957941794	1.28530061018282	0.0349858495169318	0.317418785644184	237	WDR82,GNAS,METTL3,NSUN2,ZCCHC4,ALKBH8,METTL17,RAB6A,AMT,PRDM2,PRMT7,TDRD5,DYDC1,TARBP1,PCMTD2,SUV39H1,MTR,TRMT2B,EED,NSD1,KIAA1429,PRDM8,WHSC1L1,HENMT1,PCMTD1,METTL1,RRP8,SETDB1,DPH5,ZFP57,FBXO11,SMYD1,EZH2,METTL2B,EZH1,SMYD5,METTL21C,CAMKMT,METTL13,TET2,METTL21A,TRMT1L,RBBP5,SETD7,SETD1B,MECOM,NOP2,FTSJ3,CTCFL,PLD6,TDRKH,TRMT1,TFB2M,PRDM9,SETDB2
GO:0042446	hormone biosynthetic process	GO_HORMONE_BIOSYNTHETIC_PROCESS	-0.368818037668737	-1.4570863373924	0.0350849520032449	0.317462226997103	47	HSD17B6,SRD5A3,CYP11A1,FDX1L,DUOX2,TG,FDXR,AKR1C3,STAR,RDH8,CHST8,CYP21A2,STARD5,HSD17B14,FSHB,AKR1B15,HSD3B2
GO:0003333	amino acid transmembrane transport	GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORT	-0.333803980641652	-1.41042819225194	0.0352794399648823	0.317684691546078	65	SLC1A6,SLC36A2,SLC1A1,SLC7A3,SLC6A17,SLC38A2,SLC7A10,SLC17A7,SLC7A8,SLC7A2,SLC25A22,SLC1A4,SLC38A1,SLC38A8,SLC6A14,SLC7A4,SLC32A1,SLC7A9,SLC17A6,SLC38A11,SLC6A9,SLC7A13,SLC6A12,SLC7A11,SLC38A5,SLC7A14
GO:2000142	regulation of dna templated transcription initiation	GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION	0.432921183438151	1.50404486478439	0.0353275730066718	0.317684691546078	31	PSMC6,TAF1,PSMC5,SETX,CREB1,NKX2-5,CTNNBIP1,HEY2,MITF,HMGB1,GTF2F2,FOSL1,SRF,TWIST1,RRN3,PAXIP1,IRF8
GO:0061572	actin filament bundle organization	GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION	-0.381846722404716	-1.46262658621981	0.0353926795394472	0.317684691546078	41	EZR,BAIAP2L2,LIMA1,BAIAP2,RHOD,DPYSL3,FMN2,RHOA,SHROOM2,CDC42,PAWR,SWAP70,PDCD10,ACTN1,KCTD13,FSCN1,CORO1B,PTK2B
GO:1901616	organic hydroxy compound catabolic process	GO_ORGANIC_HYDROXY_COMPOUND_CATABOLIC_PROCESS	-0.330289773959528	-1.4081576966746	0.0355696466177594	0.318424017328133	68	SMPDL3B,CHDH,SMPD3,MTMR7,ALDH3B1,HAO1,ACADL,LIPC,SRD5A3,LRTOMT,SMPDL3A,GK,AKR1C3,SLC6A3,INPP5E,CYP4F2,INPP5K,ALDH3B2
GO:0043271	negative regulation of ion transport	GO_NEGATIVE_REGULATION_OF_ION_TRANSPORT	0.299830717465327	1.35465710839927	0.0358386832399945	0.319981453012789	116	AGT,GPM6B,OPRL1,AKT2,BEST3,DRD4,VIP,CALM3,NEDD4L,ATP1A2,DRD2,PPIF,PCSK9,CAV3,PLN,PLCB4,AGTR2,KCNH2,SLC26A5,CALM1,HAMP,MTOR,KCNA5,GABBR1,NPY5R,KCNRG,SEMG1,GRK6,ANK3,MAOB,SLC30A1,GNAO1,FGF12,TRDN,SUMO1,LILRB1,PRKCE,COMMD1
NA	regulation of nfat protein import into nucleus	GO_REGULATION_OF_NFAT_PROTEIN_IMPORT_INTO_NUCLEUS	0.531113295876034	1.55187854110789	0.0360561286125825	0.320796708906386	16	AKAP1,GSK3B,AKAP6,PPP3R1,MTOR,TNF,SPPL3,PPP3CB,CHERP,AKAP5,DYRK2
NA	organ maturation	GO_ORGAN_MATURATION	-0.509305793726016	-1.55761206201356	0.0361206038845871	0.320796708906386	17	BMP2,RYR1,ANO6,GATA3,THBS3,LEP,RHOA,PLXNB1,RET,PHOSPHO1,FGFR3,IGF1
NA	coenzyme biosynthetic process	GO_COENZYME_BIOSYNTHETIC_PROCESS	0.303031722291024	1.35807645620706	0.0370623866397454	0.328294719551008	110	ME1,PANK3,DLAT,AGK,ATPIF1,ACOT6,ACOT2,DLD,LIPT2,HAAO,FPGS,COASY,PDHA1,LIAS,ACOT11,NMNAT3,ACSF2,COQ9,NFS1,ELOVL6,PDHX,PANK4,ACOT8,MOCS2,PDHB,GPHN,RFK,ACACB,GCDH,TPK1
GO:0034762	regulation of transmembrane transport	GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT	0.233846630543812	1.23267184914145	0.0374263565891473	0.330148448888484	395	SLC17A3,SHANK3,AGT,NLGN3,KCNH7,PRKACA,CACNA2D4,OPRL1,AKT2,PDGFB,SCN7A,ANK2,SCN1A,NRXN1,DLG4,CATSPER2,DRD4,KCNJ3,TRPV2,SCN5A,CALM3,CACNA2D1,KCNK13,APOC3,RYR2,S100A1,CLCN6,SHANK1,CACNA2D2,WNK1,TPCN1,NEDD4L,CAPN3,XCL1,ATP1A2,LGALS3,DRD2,HRC,OPRK1,CLCN4,RNF207,KCNJ2,VAMP2,KCNJ1,PPIF,PCSK9,WNK2,CXCL11,FXYD3,GJA1,ARF1,CACNG1,RASGRF1,AKAP6,CAV3,DMD,VDAC2,VDAC3,CXCR3,UCN,FXYD1,PLN,SLC8A1,KCNH2,ANO1,SLC26A5,CALM1,AHNAK,KCNJ13,GLRX,KCNA6,CACNA1C,KLHL24,TSPAN13,GJA5,HAMP,MTOR,KCNA5,KCNRG,SEMG1,SCN3A,PARK7,KCNMA1,GRK6,CA2,HOMER1,VDAC1,CACNA1B,P2RX7,CYBA,ANK3,KCNIP2,CXCL9,PLCG1,CRHBP,PTAFR,BSND,ZP3,SLC30A1,HTT,CATSPER4,FGF12,CACNA1E,TRDN,OAZ1
GO:0060425	lung morphogenesis	GO_LUNG_MORPHOGENESIS	-0.369967468506927	-1.44724240800138	0.0374907117605998	0.330148448888484	45	RDH10,BMP4,KRAS,GRHL2,FGFR2,MAP2K2,FOXF1,FOXA1,SOX11,CTNNB1,DLG5,WNT7B,RSPO2
GO:0030277	maintenance of gastrointestinal epithelium	GO_MAINTENANCE_OF_GASTROINTESTINAL_EPITHELIUM	-0.530696775901526	-1.56341531083131	0.0375949613661451	0.330148448888484	15	SERPINA3,MUC2,RBP4,MUC6
GO:0071867	response to monoamine	GO_RESPONSE_TO_MONOAMINE	0.422028595852658	1.4878173961144	0.0376639941690962	0.330148448888484	33	GNAS,PRKACA,HDAC2,APP,ADRB2,LRRK2,GNG2,RYR2,GSK3B
GO:0002683	negative regulation of immune system process	GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS	-0.227762927160278	-1.22938916278638	0.0377980857621803	0.330463264092205	321	SMPDL3B,CD55,TYRO3,APOA2,CNR1,EZR,CCL3,CCL28,TARBP2,TRAF3IP1,RARA,BMP4,C4BPA,TNFRSF21,PTPN2,HOXA7,HTRA1,LY96,ANGPT1,CEBPB,ALOX15,HLA-DRB5,FOXF1,SOX11,HIST1H4C,SERPING1,RPS19,SARM1,LEO1,ANXA1,GAS2L1,PLA2G2D,CTNNB1,C4BPB,NLRP6,TJP2,CNR2,CCL21,IRF4,ADIPOQ,BMP5,MMP28,IRAK3,CASP3,MASP1,LILRB2,TRIM38,NOV,PPARG,HIST1H4D,NR1H3,FAS,PGLYRP1,C5,ZNF675,CLDN18,HIST1H4E,TLR9,ADCYAP1,THBS1,PDPK1,GAL,CARTPT,HOXB8,IL2RA,MAFB,FCRLB,MIF,MYC,NFE2L2,VTCN1,HLA-DRB1,GPAM,PTGER4,IFI16,TRIB1,DLG1,PLA2G2F,INHBA,PAWR,IL20RB,CD276,CUEDC2,IL4R,UBQLN1,CD46,PF4,BANK1,IL10
GO:0006766	vitamin metabolic process	GO_VITAMIN_METABOLIC_PROCESS	-0.289171872099281	-1.34447165076808	0.0378970163618864	0.330469836979559	110	PTGIS,LRP2,SHMT1,AOX1,CYP26B1,LRAT,ALDH1L1,CYP11A1,AMN,CYP26A1,MTHFD1L,PC,PDZD11,RBP1,BTD,SLC19A3,PSAT1,MMADHC,HLCS,CYP4F11,DHFR,NAMPT,PLTP,FASN,CYP4F2,VKORC1,ALDH1L2,CYB5A,VKORC1L1,TTPA,SLC2A1,ACPP,SLC23A2
GO:0090100	positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	-0.297734763100775	-1.35558665830554	0.0386056438226227	0.335594622582359	97	GDF5,CDKN2B,SULF1,SNW1,TGFBR1,BMP4,BMP2,NPNT,NEO1,CYR61,SOX11,CRB2,GDF10,ACVR1,MEN1,MSX2,LEFTY1,MSTN,BMP5,DAB2,SMAD2,FGF9
GO:0071320	cellular response to camp	GO_CELLULAR_RESPONSE_TO_CAMP	-0.368721867674553	-1.44236985432706	0.0386841097926189	0.335594622582359	45	ASS1,CFTR,EZR,WT1,AQP1,GPD1,AQP8,WNT10B,STAR,CPS1,ADIPOQ,RAPGEF3,ITPR3,INPP5K,SLC8A3
GO:1903036	positive regulation of response to wounding	GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING	-0.266076844244638	-1.30322253339858	0.0389562114340941	0.336825928727645	153	VTN,PLA2G2A,C3,CNR1,CCL3,TNFSF11,MAPK13,IL17B,IL18,FFAR3,WNT5A,OSMR,ANO6,RPS19,ANXA1,AGTR1,INSL3,F7,S100A12,IL6ST,HPSE,LPL,F2,TNFRSF1A,FABP4,IL17RC,TLR10,HOPX,VAMP8,S100A9,IL17F,NLRP12,TLR9,MYOD1,SOX15,THBS1,F2R,CREB3L3,CCL4,TLR2,NFE2L2,FCER1A,CCL18,IL17RB,PTGER4
GO:0002697	regulation of immune effector process	GO_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	-0.219034088478756	-1.20667804886426	0.0390261771253064	0.336825928727645	392	VTN,CFB,C3,CD55,RBP4,C4A,C2,APOA2,SNRPB2,CCL19,TARBP2,CFI,TRAF3IP1,CFH,RARA,C9,CPA3,FFAR3,TRAF3IP2,ALPK1,WNT5A,C4BPA,KLK7,LENG9,FGF7,HTRA1,ANGPT1,GATA3,FOXF1,MZB1,ANXA5,SERPING1,IL27,MB21D1,RPS19,ANXA1,CLCF1,TMEM39A,XBP1,C4BPB,ATP6V1H,NR4A3,RIPK2,APOBEC3F,HCAR1,FGFBP1,UBA52,IRF4,MSTN,RIPK3,IRAK3,PHYHIP,LEP,MASP1,AP1S3,ZCCHC17,VAMP8,HPR,C5AR1,TRIM38,WHSC1,SLC25A19,LMCD1,ZBTB1,EIF2AK4,KLK5,PROS1,PGLYRP1,C5,YIPF1,NLRP3,IL5,HIST1H3C
GO:0050879	multicellular organismal movement	GO_MULTICELLULAR_ORGANISMAL_MOVEMENT	0.406096677858547	1.47090692705003	0.0392128464616109	0.337571460843433	37	ITPR1,ADRB2,DMPK,HIPK2,TCAP,CLN8,TNNI3,MYH7,VTI1A,MTOR,IKBKB,HOMER1,TNNC2,GIGYF2,TNNT3,MYH8,ASCL1,TNNT1
GO:0001510	rna methylation	GO_RNA_METHYLATION	0.382844842142246	1.44806374392803	0.039412854598766	0.338427725967975	45	METTL3,NSUN2,ALKBH8,TARBP1,TRMT2B,KIAA1429,HENMT1,METTL1,METTL2B,TRMT1L,FTSJ3,TRMT1,TFB2M,EMG1,METTL16,NSUN4,METTL15,LCMT2,NSUN3,WDR4,MEPCE,MRM1,TRMT61B
GO:1990089	response to nerve growth factor	GO_RESPONSE_TO_NERVE_GROWTH_FACTOR	0.408692887607533	1.4699812611181	0.0395283446712018	0.338490151957013	36	EHD1,RAPGEF1,APP,RAPGEF2,KAT2A,EP300,CREB1,APC,SORT1,BPTF,NFKB1
GO:0006839	mitochondrial transport	GO_MITOCHONDRIAL_TRANSPORT	0.280521045348657	1.31876392507227	0.0396212477335303	0.338490151957013	151	ATP5L,RHOT2,BAD,MICU1,DYNLL2,ATPIF1,MFN2,SLC25A30,MOAP1,CAMK2A,GZMB,PRKAB2,ATP5A1,PPIF,ATP5G2,ATP5D,MIPEP,GSK3B,PRKAA2,ATP5O,ATP5B,PDE2A,NMT1,AIP,TIMM8B,IMMP1L,ATP5G3,PPP3R1,PPP1R13B,PMPCA,TIMM17B,FLVCR1,SLC25A32,ATF2,VDAC1,TMEM102,ACACB,TIMM22,CHCHD4,BID,NDUFA13,MAPK8,SLC25A12,MRPL18,YWHAG,BAK1,SLC25A10,TOMM40L
GO:0045109	intermediate filament organization	GO_INTERMEDIATE_FILAMENT_ORGANIZATION	-0.486325180874445	-1.53170743724402	0.0397932143012294	0.339098631235287	19	KRT71,AGFG1,TCHH,KRT25,NEFM,KRT14,MTM1
GO:0016571	histone methylation	GO_HISTONE_METHYLATION	0.334380308800867	1.39533438029998	0.0406557030672254	0.34499789970178	73	WDR82,PRDM2,PRMT7,DYDC1,SUV39H1,EED,NSD1,WHSC1L1,SETDB1,SMYD1,EZH2,EZH1,TET2,RBBP5,SETD7,SETD1B,MECOM,CTCFL,PRDM9,SETDB2
GO:0007223	wnt signaling pathway calcium modulating pathway	GO_WNT_SIGNALING_PATHWAY_CALCIUM_MODULATING_PATHWAY	0.415348625302532	1.47450311837228	0.0406904831199069	0.34499789970178	34	PLCB2,TNRC6C,CALM3,CAMK2A,GNG2,TNRC6A,CALM1,PPP3R1,TNRC6B,GNAT2,FZD6,MOV10,WNT11,GNAO1
GO:0000904	cell morphogenesis involved in differentiation	GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION	-0.210536534432589	-1.18366864082565	0.0411226963404305	0.347786421813792	488	SEMA3F,MATN1,NTNG1,LHX9,SEMA3C,LHX4,TYRO3,LRRN1,EZR,SLITRK2,PARD6B,PAX8,KIF5A,EFNB3,GBX1,WT1,PDZD7,FLRT3,TGFBR1,BMP4,WNT5A,CUL7,ULK2,BMP2,FMOD,MET,SLITRK4,GAP43,KRAS,GATA3,GRHL2,UNC5D,FGFR2,NEO1,EFNA5,S100A6,ADAM15,RTN4,GBX2,SEMA3A,LRFN4,SEMA3B,FLRT2,UNC5A,OTX2,PLXNB2,SPTBN4,EVL,COBL,ATP2B2,CTNNB1,BMPR1B,LRRC38,PLXNA2,PARVA,BRSK2,SLIT3,FEZF1,ISL2,NR4A3,ANTXR1,TNMD,MSX2,HIF1A,ROBO2,BAIAP2,ARTN,ST14,EPYC,RAB10,CDH11,CASP3,FZD3,USP33,CHRNB2,VPS33A,CDK5,CDH4,EXT1,PAK3,GDNF,LMX1A,BOC,LINGO3,HGF,TLR9,CTNND2,STXBP1,ARL13B,EPHA2,DOCK7,SPTBN2,RILPL2,ATL1,NRCAM,LRFN3,NTN4,SEMA4A,NODAL,BASP1,SRGAP2,FRMD6,ARHGEF26,C1GALT1C1,SLITRK5,PLXNA4,LLGL1,ECM2,POU4F2,SPTAN1,ISPD
GO:0032970	regulation of actin filament based process	GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS	0.244830881244215	1.25127336027997	0.0413139991695679	0.348528624573347	293	AMOT,SHANK3,SPTB,PIK3R1,TRPM4,GPM6B,ANK2,SERPINF2,CLASP1,SSH2,CTNNA3,DLC1,DIXDC1,SCN5A,ROCK2,TSC1,RYR2,SHANK1,MYBPC3,EPHA1,ATP1A2,RNF207,KCNJ2,BMP10,ARAP1,CCL24,LMOD1,LMOD3,ARF1,ADD1,CAV3,SPIRE1,CSF3,PKP2,PLN,ACTR3B,FAM21C,PPP1R9A,FZD10,EPHA3,AKAP13,LIMK1,LATS1,EP300,CAPZB,WASL,TMOD1,CACNA1C,GJA5,MTOR,DAPK3,S1PR1,SEMA5A,TEK,PPFIA1,BAG4,ARFGEF1,JMY,FHOD3,ARHGDIB,CCDC88A,TNNT2,MYLK3,SSH1,WNT11,RDX,C15orf62,MKKS,KANK1,SMAD3,MLST8,CFL2,SUMO1,ATP2A2,PRKCE,BCAS3,ODAM,PFN2,ARF6,TMEFF2,PROX1,NTRK3,EPHA5,ABL2,CAPG,PRKCQ,NOX4,MEF2C,SYNPO,JUP
GO:0007190	activation of adenylate cyclase activity	GO_ACTIVATION_OF_ADENYLATE_CYCLASE_ACTIVITY	0.414428102467833	1.4712352279602	0.041727299185099	0.351135222642608	34	GNAS,ADRB1,ADRB2,CALM3,GIPR,GLP1R,VIPR2,ADCY7,ADCY5,CALM1,RAF1,ADCY8,ADCY9,ADCY4,ADORA2B,CALCR,CAP2
GO:0040001	establishment of mitotic spindle localization	GO_ESTABLISHMENT_OF_MITOTIC_SPINDLE_LOCALIZATION	0.465984895333894	1.50245117564319	0.0418426949781419	0.351228207721759	23	NDE1,CLASP1,CENPA,PAFAH1B1,ARHGEF2,EYA1,GPSM2,PAX6,HTT,ESPL1,SPRY2,KPNB1
GO:0045687	positive regulation of glial cell differentiation	GO_POSITIVE_REGULATION_OF_GLIAL_CELL_DIFFERENTIATION	-0.415926334772076	-1.47801966831916	0.0419885344961155	0.351575639586877	30	NKX6-1,SPINT1,BMP2,PRMT5,CLCF1,TP73,IL6ST,MAG,PPARG,RNF112
NA	regulation of energy homeostasis	GO_REGULATION_OF_ENERGY_HOMEOSTASIS	0.52241688678982	1.52646819881297	0.0421150450701608	0.351759904978067	16	BMP8A,FLCN,OPRK1,PRKAA2,FOXO1,CD36,PASK,PPARGC1A,METRNL
GO:0035904	aorta development	GO_AORTA_DEVELOPMENT	0.395884463790365	1.45063423324496	0.042492047426258	0.354030276328674	39	TBX2,PRICKLE1,NDST1,EYA1,NKX3-1,SUFU,DCTN5,NPRL3,SIX1,DLL4,MYLK,LTBP1,HEY2,FGF8,PLXND1,PROX1,SRF,SEC24B
GO:0010656	negative regulation of muscle cell apoptotic process	GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS	0.433458163991387	1.48144635675145	0.0426926095606622	0.35420468355112	29	LRP6,HAND2,NACA,HMGCR,LIFR,BAG3,GSK3B,JAK2,SIRT4,SIRT5,NKX2-5,HEY2
GO:0044042	glucan metabolic process	GO_GLUCAN_METABOLIC_PROCESS	0.36082882666526	1.41841048200266	0.0427234407373008	0.35420468355112	54	AKT2,PYGB,PYGM,PGM5,CALM3,PHKG1,GYS1,GSK3B,PFKM,GCK,STK40,PPP1R3A,CALM1,PPP1R3B,PHKA2,PHKB,GYG1,PPP1CB,PPP1R3E,EPM2A,PRKAG3,PHKG2
GO:0030031	cell projection assembly	GO_CELL_PROJECTION_ASSEMBLY	-0.240572981652211	-1.24897526822205	0.0429842538068432	0.35490486757858	232	C5orf42,EZR,KLF5,PIP5K1A,TRAF3IP1,IQCB1,C11orf63,IFT57,ANO6,RFX4,WDR35,BBS7,LPAR1,SSX2IP,KIF3A,CCDC114,ATP6V0D1,SH2B1,CCL21,TTLL1,WHAMM,WDR19,SNX10,RFX2,B9D2,DNAH1,TTC30B,RHOD,EMP1,SPEF2,DZIP1L,DYNC2LI1,ONECUT1,CEP89,PCM1,TTC26,INPP5K,STX2,IFT20,RAP2B,CEP41,ARL13B,E2F4,FBF1,CCDC13,TTYH1,TMEM231,RAB17,RP1L1,KIAA0586,SRGAP2,ARHGEF26,TTC8,CDC42,AKAP4,EMP3,FAM161A,BBS10,DNAH5,RAB23,ABL1,LRRC6,ABCC4,DYNC2H1,CLUAP1,RAC1,HSPB11,RSG1,IFT140,RAP1A,FSCN1,SEPT2,EHD3,KIF24,MYH10,WASF3,TMEM237,TCTN2
GO:0006734	nadh metabolic process	GO_NADH_METABOLIC_PROCESS	0.413272632353418	1.46713326593818	0.0430187718277066	0.35490486757858	34	IDH3B,PGAM2,PGAM1,OGDH,PFKM,GCK,MDH2,MDH1,PFKFB4,PFKP,ALDOC,VCP,ALDOA,HK3,ENO2,DLST,GPI,PGK1,IDH3G,GPD1L
GO:0032410	negative regulation of transporter activity	GO_NEGATIVE_REGULATION_OF_TRANSPORTER_ACTIVITY	0.357233016052659	1.41492901148143	0.0433588875022286	0.356836223306849	56	AGT,OPRL1,DRD4,CALM3,NEDD4L,ATP1A2,DRD2,PPIF,PCSK9,CAV3,PLN,CALM1,HAMP,KCNRG,GRK6,ANK3,FGF12,TRDN,SUMO1,PRKCE,TWIST1,CASQ2,ACTN2,GSTO1,DRD3,KCNAB1,KCNQ1,INSR
GO:0001101	response to acid chemical	GO_RESPONSE_TO_ACID_CHEMICAL	-0.228455215415336	-1.22346470523415	0.0436543050974714	0.358391197458753	300	KRT8,ASS1,WNT6,RBP4,SHMT1,CCL19,UFL1,OSR1,LIPC,RARA,CYP26B1,ALDOB,SNW1,FFAR3,AQP1,BCHE,BMP4,WNT5A,SLC10A3,AQP3,CTGF,T,WNT9A,CEBPB,PTK7,PEMT,SOCS1,TACR1,IPO5,ZNF354A,KLF4,XBP1,WNT10B,CAT,P2RY4,CCL21,AKR1C3,DGAT2,EGFR,CHUK,WNT7B,HIF1A,CPS1,ADIPOQ,TYMS,CASP3,LEP,CCNB1,GLRA4,HLCS,PPARG,SPARC,ABCA1,PTGER2,RAPGEF3,DHFR,LTK,SST,FAS,HMBS
GO:0006665	sphingolipid metabolic process	GO_SPHINGOLIPID_METABOLIC_PROCESS	-0.277709960542737	-1.31600581160564	0.0440053339798763	0.359020369530495	123	SMPDL3B,GAL3ST1,P2RX1,SMPD3,ALDH3B1,ARSF,DEGS2,ORMDL2,PRKD1,ARSH,ITGB8,SGPP2,SMPDL3A,ALDH3A2,SMPD2,ALOX12B,SGPL1,ARSI,ARSD,CERS2,SGMS2,NEU1,KDSR,SERINC2,SFTPB,NEU2,ALDH3B2,ST3GAL5,BAX,ARSK,CLN3,DEGS1,SPNS2,ARSE
NA	negative regulation of chromatin modification	GO_NEGATIVE_REGULATION_OF_CHROMATIN_MODIFICATION	0.388783818241595	1.44051312412941	0.0441473988439306	0.359020369530495	41	TET1,SMARCB1,PHF2,JARID2,TRIP12,HMGA1,KDM5A,UCN,UBR5,AICDA,SPI1,BCOR,APOBEC1,ASF1A,UBE2B
GO:0007272	ensheathment of neurons	GO_ENSHEATHMENT_OF_NEURONS	0.319624619245565	1.36662185658324	0.0442174491009585	0.359020369530495	84	LAMA2,XK,PPARD,AKT2,MPDZ,EIF2B5,ANK2,TSC1,SH3TC2,QKI,SERINC5,PTEN,PIKFYVE,NFASC,OLIG2,SBF2,MAL,SOD1,DICER1,GPC1,FAM126A,EIF2B4,PRX
GO:0051349	positive regulation of lyase activity	GO_POSITIVE_REGULATION_OF_LYASE_ACTIVITY	0.361972266461332	1.41781514253928	0.0442443086380044	0.359020369530495	53	GNAS,ADRB1,VIP,ADRB2,CALM3,GIPR,FTMT,GLP1R,VIPR2,ADCY7,ADCY5,GUCA1C,CALM1,RAF1,ADCY8,ADCY9,PARK7,ADCY4,ADORA2B,FXN,CALCR,CAP2
GO:0001574	ganglioside biosynthetic process	GO_GANGLIOSIDE_BIOSYNTHETIC_PROCESS	0.511463090982087	1.51940937103366	0.044264246391906	0.359020369530495	17	ST6GALNAC4,ST8SIA6,ST3GAL6,ST3GAL3,ST3GAL2,ST6GALNAC3
GO:1902590	multi organism organelle organization	GO_MULTI_ORGANISM_ORGANELLE_ORGANIZATION	0.477072416890227	1.50153068956717	0.0445896314342137	0.359843363945737	21	LRSAM1,VPS4A,CHMP7,VPS37B,MITD1,VPS37C,CHMP6,TSG101,VPS37A,CHMP1B,CHMP4B,CHMP4C
GO:0002526	acute inflammatory response	GO_ACUTE_INFLAMMATORY_RESPONSE	-0.324550902779174	-1.37951760847466	0.0446655866697524	0.359843363945737	67	ASS1,SERPINA3,APOA2,HP,NUPR1,ANO6,GATA3,CEBPB,OPRM1,TACR1,ACVR1,STAT3,HIF1A,F2,SAA1,ORM1,BDKRB2,MBL2
GO:1903524	positive regulation of blood circulation	GO_POSITIVE_REGULATION_OF_BLOOD_CIRCULATION	0.313751844249963	1.35893530727146	0.0446864308167908	0.359843363945737	90	AGT,PTPRM,PPARD,TRPM4,ADRB1,VIP,NPY1R,ADRB2,HRH2,RYR2,HRC,RNF207,ADRA2C,TACR3,GJA1,UCN,AGTR2,ADA,ESR2,GJA5,NKX2-5,ACE2
GO:0006379	mrna cleavage	GO_MRNA_CLEAVAGE	0.519459776039422	1.51782771334056	0.0449586469658954	0.36117137395514	16	NCBP1,WDR33,TUT1,CLP1,CPSF1,NCBP2,MOV10
NA	organ formation	GO_ORGAN_FORMATION	-0.396505760896089	-1.45334887279586	0.0452405276951095	0.362570514813663	34	PAX8,NKX3-2,RDH10,BMP4,HOXA3,FGFR2,MAP2K2,CTNNB1
GO:0072512	trivalent inorganic cation transport	GO_TRIVALENT_INORGANIC_CATION_TRANSPORT	-0.391976823649992	-1.44728187401632	0.045697012802276	0.365359014471404	35	STEAP3,STEAP1,ATP6V1C2,ATP6V1B1,ATP6V0D1,ATP6V1H
GO:0051865	protein autoubiquitination	GO_PROTEIN_AUTOUBIQUITINATION	0.370692470891009	1.42154120883122	0.0462147095846071	0.368622541378643	48	UHRF1,UBE4B,LRSAM1,RNF187,RNF213,RNF220,UBE2T,RNF141,LTN1,TRIM13,CNOT4,MARCH5
GO:1903170	negative regulation of calcium ion transmembrane transport	GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT	0.449675541305745	1.48046800401981	0.0469985869226111	0.373988755511841	25	OPRL1,DRD4,CALM3,ATP1A2,DRD2,PLN,CALM1
GO:0015711	organic anion transport	GO_ORGANIC_ANION_TRANSPORT	-0.219975635218077	-1.20090659414571	0.0474122430914774	0.375923364227417	359	SLC22A24,SLC1A6,PDPN,SLC26A9,CFTR,CA12,SLC36A2,APOA2,APOC1,PLIN2,PITPNM3,SNAP25,NMB,CA9,EMB,AQP1,MFSD2A,SLC10A3,SLC22A4,BEST1,SLC1A1,SLC7A3,SLC10A1,SLC4A4,SLC17A5,ANXA1,SLC6A17,SLC38A2,SLC22A31,ABCB11,SLC22A25,SLC25A6,SLC7A10,SLC17A7,SLC7A8,SLC7A2,ATP8B3,SLC35A3,ATP10B,SLC22A20,PRAF2,LEP,PLA2G4F,ABCA7,SLCO5A1,CALHM1,SLC25A22,TNFAIP8L3,SLC1A4,PPARG,FOLR3,CA3,UNC13B,ABCA1,SERINC2,BDKRB2,SLC16A1,ARL6IP5,ATP11C,SLC38A1,PRELID1,SLC22A8,SLC13A5,AGXT,ATP9A,SLC38A8,SLCO1B3,KCNN4,STXBP1,CROT,FABP1,CA5A,CACNB4,SLC6A14,ABCG1,SLC27A4,TRIAP1,SLC22A17,SLC7A4,CLN3,SLC32A1,CYB5R4,SLC2A2,SLCO2A1,PITPNM1,OSBPL8,SLC2A1,SLC7A9,SLC3A2,SLC23A2,SLC17A6,SLC38A11,GRM2,SLC6A9,AQP9,PSEN1,SLC16A2,ABCC4,SYT1,SLC16A8,SLC7A13,PLA2G4A,SLC16A4,SLC6A12,ACACA,SLC7A11,SH3BP4
NA	oxidoreduction coenzyme metabolic process	GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS	0.306832750318914	1.34603518978579	0.0474650712408355	0.375923364227417	97	IDH3B,ME1,OGDHL,NNT,DLD,PGAM2,PGAM1,RPIA,OGDH,HAAO,DHTKD1,HMGCR,PDHA1,NMNAT3,PFKM,GCK,COQ9,MDH2,MDH1,PFKFB4,PDHX,PFKP,ALDOC,VCP,PDHB,ALDOA,HK3,ENO2,GALK1,IDH1,NDUFA9,DLST,NMNAT2,COQ2,GPI,PRDX5,TKT,COQ5,ADPGK,PGK1,IDH3G,GPD1L,NMNAT1,DCXR,PGAM4,COQ7
GO:0032677	regulation of interleukin 8 production	GO_REGULATION_OF_INTERLEUKIN_8_PRODUCTION	-0.343142985487889	-1.39682346256766	0.0477348116508384	0.377172244170709	54	APOA2,WNT5A,ANXA4,ANXA1,KLF4,PYCARD,RIPK1,ADIPOQ,IL17F,TLR9,F2R,TLR2,ELANE,PTGER4,AFAP1L2,IL10,MAP2K5,CAMP,TLR3
GO:0032026	response to magnesium ion	GO_RESPONSE_TO_MAGNESIUM_ION	-0.447412408557895	-1.48398805144115	0.0479148375768218	0.377403097284902	23	SLC34A1,C3,LIPC,TNFRSF11B,SNCA,FBP1,RYR3,KCNA1,THBS1,MDM2
GO:0001941	postsynaptic membrane organization	GO_POSTSYNAPTIC_MEMBRANE_ORGANIZATION	0.453616982412923	1.478123625181	0.0481380730066537	0.377403097284902	24	SHANK3,NLGN3,NRXN1,DLG4,MUSK,CDH2,DNAJA3
GO:0022412	cellular process involved in reproduction in multicellular organism	GO_CELLULAR_PROCESS_INVOLVED_IN_REPRODUCTION_IN_MULTICELLULAR_ORGANISM	-0.23908472495774	-1.24045356014233	0.0481874562109142	0.377403097284902	231	CFTR,TDRD1,TARBP2,RARA,WT1,SPANXB1,TGFBR1,AGFG1,BMP4,PYGO1,DMRT1,FSHR,GALNTL5,IQCF1,SPAG6,ACVR1,INSL3,REC8,PTCHD3,CTNNB1,BMPR1B,FAM9A,SLIT3,YBX2,RFX2,PAQR5,SERPINA5,ROBO2,MOV10L1,PRDM14,CCNB1,TSSK6,KIAA0196,IZUMO1,FBXO5,TAF4B,FMN2,DDX25,TTC26,BAX,DND1,HMGB2,RNF8,NPM2,AURKC,NPHP1,TMF1,FSHB,GPR149,PYGO2,FOXO3,INHBA,PABPC1L,RPS6,CEP57,FOXL2,CATSPER1,CHD5,BCL2,ADAD1,OSBP2,ADAM2,RPS6KA2,PRDM1,FNDC3A,CAPZA3,KLHL10,RAN,CCDC63,SPACA1
GO:0009118	regulation of nucleoside metabolic process	GO_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS	0.377599048220291	1.42143844014834	0.0482125168842864	0.377403097284902	44	FLCN,ATP7A,ATPIF1,PPARA,APOC3,PGAM1,PPIF,PINK1,HDAC4,PRKAA2,GCK,PARK7,NCOR1,VCP,P2RX7
GO:0090322	regulation of superoxide metabolic process	GO_REGULATION_OF_SUPEROXIDE_METABOLIC_PROCESS	0.466371486012638	1.48549782657355	0.0485721124634052	0.379107114412732	22	AGT,FBLN5,TNF,PARK7,CYBA,SOD1,AATF,CD36
GO:0060259	regulation of feeding behavior	GO_REGULATION_OF_FEEDING_BEHAVIOR	-0.47658142853628	-1.50101896272128	0.0486554585342543	0.379107114412732	19	MC3R,CNR1,RETN,NPY2R,STAT3,NR4A3,EIF2AK4
GO:1902305	regulation of sodium ion transmembrane transport	GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT	0.376906365373374	1.41883089643212	0.0490229626294462	0.380380942464449	44	AGT,DRD4,SCN5A,NEDD4L,ATP1A2,PCSK9,WNK2,FXYD3,ARF1,CAV3,DMD,FXYD1,GLRX,ANK3,FGF12,PRKCE,SNTA1,COMMD1,ATP1B2,UTRN,STOM
GO:0008211	glucocorticoid metabolic process	GO_GLUCOCORTICOID_METABOLIC_PROCESS	-0.504136598616718	-1.51480361888362	0.0492023291555729	0.380380942464449	16	HSD11B1,CYP11A1,SERPINA6,YWHAH,STAR,CYP21A2
GO:0045862	positive regulation of proteolysis	GO_POSITIVE_REGULATION_OF_PROTEOLYSIS	0.235671708054834	1.22408085884274	0.0492588333517115	0.380380942464449	342	KLKB1,CARD8,DDX3X,BAD,ADRM1,CYFIP2,AURKAIP1,RNF144B,CDC26,RNF40,FBXW7,OSBPL7,TRIB2,ATPIF1,PRICKLE1,HDAC2,DLC1,PSMD11,APP,LRRK2,PSMD2,PSMC6,CAPN3,TAF1,MAD2L1,RNF180,RNF14,GOLGA2,HSPD1,PDCD2,PINK1,CTSH,NKX3-1,FZR1,BTRC,GSK3B,JAK2,CAV3,PTEN,REST,CDK5RAP3,ACER2,ANAPC1,IFI27,PSMC5,PSMB7,PSME4,GORASP1,DNAJA3,DNAJB2,SGTA,RNF144A,EP300,MTCH1,MEFV,APOPT1,TNFRSF10B,TNFSF10,CASP8AP2,CR1,RNF125,ANAPC11,TNF,PDCD6,ARIH2,PSMA8,CDKN1B,SEMG1,SOCS4,CDK1,PSMD8,TRIM32,VCP,PSMB10,TRIB3,DLGAP5,FAM162A,PSMD3,PSMB1,CSNK1A1,HMGB1,SMAD7,SMAD3,SOX7,RHBDD1,SUMO2,FASLG,PSMA5,SUMO1,PSMB9,BID,USP5,NDUFA13,HPN,EGF,CHFR,ESPL1
GO:0002444	myeloid leukocyte mediated immunity	GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY	-0.372923183657245	-1.42008266756466	0.0494736842105263	0.380380942464449	40	MRGPRX2,CCL3,ANXA3,IRAK4,NR4A3,STXBP3,SNAP23,VAMP8,LAT
GO:0009068	aspartate family amino acid catabolic process	GO_ASPARTATE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS	0.505694335397156	1.50227206152005	0.049527600059515	0.380380942464449	17	DDO,ALDH7A1,DLD,OGDH,ASRGL1,GOT2,GOT1,GCDH,DLST,PIPOX,CRYM
GO:0071276	cellular response to cadmium ion	GO_CELLULAR_RESPONSE_TO_CADMIUM_ION	-0.514864634624334	-1.5167743414492	0.0495855247494751	0.380380942464449	15	MT1E,MT1A,AKR1C3,MT1F,STAR,MT1G,CYP1A2
GO:0097066	response to thyroid hormone	GO_RESPONSE_TO_THYROID_HORMONE	-0.466900204608484	-1.49200883232475	0.0497367390452983	0.380380942464449	20	SLC34A1,BMP4,ANXA5,ANXA2,GAS2L1,LMO2,KEAP1
GO:0071241	cellular response to inorganic substance	GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE	-0.26427318173548	-1.2849414435704	0.0498316829250313	0.380380942464449	145	ATP13A2,SLC34A1,MT1M,MT1E,AQP1,WNT5A,ALOX15,ANXA5,MT2A,KCNH1,TSPO,SNCA,CALR,SLC18A1,MT1A,CTNNB1,CEBPA,AKR1C3,MT1F,STAR,HIF1A,EIF2AK3,FBP1,FABP4,CCNB1,ADCY10,MT1G,CCNA2,RYR3,FAS,HMBS,CDH1,CPNE6,KCNA1,CYP1A2
GO:0060999	positive regulation of dendritic spine development	GO_POSITIVE_REGULATION_OF_DENDRITIC_SPINE_DEVELOPMENT	0.410611188537347	1.44756652830786	0.0498360058309038	0.380380942464449	33	CPEB3,SHANK3,NLGN3,PAFAH1B1,TIAM1,SHANK1,ARF1,PPP1R9A,MTOR,CAMK2B,ZMYND8,IL2,BHLHB9,MARCKS,ITPKA
GO:0032106	positive regulation of response to extracellular stimulus	GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS	0.367423739833688	1.40900619324971	0.0500809206977162	0.380934049971385	48	LRSAM1,WDFY3,ADRB2,ULK1,CALCOCO2,GHSR,RAB12,PINK1,CYP27B1,PRKAA2,RAB3GAP1,PIP4K2C,TRIM13,PIP4K2B,SCOC,PARK7,NPY
GO:0048193	golgi vesicle transport	GO_GOLGI_VESICLE_TRANSPORT	-0.228148537353015	-1.21626694068599	0.050134814063376	0.380934049971385	289	KIF2C,KIF18A,CD55,KIF5A,COPB1,TMED10,KDELR3,PRKD1,AREG,RAB31,TMED3,AMN,BNIP1,RGPD3,KRT18,PRKCI,SCFD1,TMED2,ANKRD28,LMAN2,PLCB3,KIF3A,SCYL1,SPTBN4,SEC24D,EXOC5,COPG2,F7,MIA3,SURF4,BCAP31,WHAMM,KDELR2,SNAP23,F2,ERGIC2,RAB10,COPB2,SEC24A,SEC13,STX18,C16orf62,SEC23B,TMEM115,GOLGA7,VAMP8,SORL1,COL7A1,GCC2,DYNC2LI1,COG1,PROS1,SNX2,PICK1,ATP9A,ATL3,F5,KIF4A,DYNLL1,KIF3C,SPTBN2,GOLGA5
GO:0034764	positive regulation of transmembrane transport	GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT	0.289554963288577	1.31631383551085	0.0503413405063076	0.381641784108629	120	SHANK3,NLGN3,PDGFB,ANK2,DRD4,TRPV2,CALM3,CACNA2D1,RYR2,S100A1,WNK1,CAPN3,XCL1,LGALS3,OPRK1,RNF207,KCNJ2,WNK2,CXCL11,ARF1,AKAP6,DMD,CXCR3,UCN,FXYD1,KCNH2,CALM1,GLRX,PARK7,CA2,P2RX7,ANK3,CXCL9,PLCG1,PTAFR,ZP3,HTT,TRDN,SUMO1,JPH2
GO:0034440	lipid oxidation	GO_LIPID_OXIDATION	0.336487181236641	1.37850410356677	0.0506103898391671	0.382819263367723	66	SLC25A17,DECR1,IVD,CYP4V2,PPARD,ACOX3,ACAD9,ACADM,ACAD10,ADIPOR2,HADH,ECI2,ETFA,PEX7,ADH7,ACOT8,HADHB,ECHS1,PLA2G7,GCDH,ACADVL,HADHA
GO:0046683	response to organophosphorus	GO_RESPONSE_TO_ORGANOPHOSPHORUS	-0.270782106142534	-1.29204614397648	0.0510034669661605	0.384927510780485	129	ASS1,CFTR,P2RX1,EZR,FOXM1,WT1,ALDOB,AQP1,AREG,PAX4,DUOX2,GPD1,LDHA,SDC1,LPAR1,AQP8,PKLR,WNT10B,SLC6A3,STAR,CPS1,ADIPOQ,TYMS,SPARC,RAPGEF3,RYR3,ITPR3,AGXT,INPP5K,SLC8A3,ASPH,ATP7B,AKAP7,JUNB,HNF4A,AQP9,HCN2,MMP19,THBD,ALDH3A1,AKR1C1,JUN,RAP1A
GO:0033120	positive regulation of rna splicing	GO_POSITIVE_REGULATION_OF_RNA_SPLICING	0.470162798966082	1.47978346000837	0.0513445176531384	0.386282403422778	21	PIK3R1,SNRNP70,RBM20,SF3B4,SETX,THRAP3,PRPF19
GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	GO_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE	0.456280258027503	1.47116101178556	0.0514125123985159	0.386282403422778	23	AGT,PDGFB,SERPINF2,HSD11B2,GJA1,AGTR2,GJA5,CYBA
GO:0009226	nucleotide sugar biosynthetic process	GO_NUCLEOTIDE_SUGAR_BIOSYNTHETIC_PROCESS	-0.473556581477757	-1.49149204345353	0.0515443763847257	0.386410625636941	19	AMDHD2,GFPT2,UAP1,PGM3,UGDH
GO:0055088	lipid homeostasis	GO_LIPID_HOMEOSTASIS	0.303661476979197	1.33401450653212	0.0517620192723561	0.387179904157224	98	EHD1,LRP5,IVD,ACOX3,FBXW7,ACAD9,FITM2,ABCA2,ACADM,TMEM97,ACAD10,ACSM2A,APOC3,LDLR,LCAT,PCSK9,CAV3,PRKAA2,PKP2,GCK,MALL,LIPG,ETFA,FABP3,USF2,NPC1,CETP,ABCB4,GOT1,GCDH,ACADVL
GO:0006399	trna metabolic process	GO_TRNA_METABOLIC_PROCESS	0.271922046579231	1.28627893445382	0.0521239723389649	0.388574738477845	158	TARS2,NSUN2,CDK5RAP1,ZBTB8OS,BRF1,PARS2,GTF3C5,ELAC2,ALKBH8,KIAA0391,GTF3C1,CTU1,TARBP1,EARS2,LRRC47,TRMT2B,LARS2,TYW5,EXOSC7,METTL1,CLP1,TRPT1,MARS,METTL2B,IARS2,OSGEP,CPSF1,AIMP2,TRMT1L,WARS,EXOSC3,TRMT1,DUS1L,LSM6,MRPL39,DUS4L,MARS2,QRSL1,TARS,PUS1,URM1,SARS2,RPP14,C2orf49
GO:0045927	positive regulation of growth	GO_POSITIVE_REGULATION_OF_GROWTH	0.25433927010938	1.25920742735058	0.052204251989044	0.388574738477845	223	DDX3X,PPARD,CDKL5,NRP1,TBX2,STAT5B,LPAR3,NCBP1,CSNK2A1,PAFAH1B1,ADRB2,TRPV2,KDM2B,HLX,PIN1,MEGF8,CACNA2D2,NEDD4L,CAPN3,YAP1,DRD2,BMP10,GHSR,IL9,NACA,MACF1,CHD7,GSK3B,AKAP6,EXOSC4,CELF1,GH1,RASAL1,UCN,DDX39B,TGFBR2,GOLGA4,LIMK1,ITSN2,H3F3A,FGFR1,EP300,ERBB4,MTOR,TBX5,TBX20,CREB1,SEMA5A,CDK1,VEGFA,TRIM32,CYBA,HYAL1,HEY2,MKKS,IL2,ZP3,CD38,AGR2,ACACB,FXN,ADAM10,L1CAM,BCL11A,PRKDC,FOXS1,FGF8,HPN,CPNE9,PROX1,NTRK3,OSBP,CDKN2AIP
GO:0031214	biomineral tissue development	GO_BIOMINERAL_TISSUE_DEVELOPMENT	-0.31557670183206	-1.35450045332926	0.0523215523215523	0.388574738477845	70	FAM20A,AMBN,BMP2,ALPL,TUFT1,ANO6,DUOX2,ALOX15,FGFR2,ITGB1BP1,DMP1,DSPP,ATP2B2,MSX2,EIF2AK3,LEP,RSPO2,MINPP1
GO:0060840	artery development	GO_ARTERY_DEVELOPMENT	0.326579882393494	1.36278400917842	0.0524703313730324	0.388574738477845	73	NRP1,TBX2,NOTCH3,PRICKLE1,HAND2,NDST1,EYA1,NKX3-1,CHD7,SUFU,DCTN5,NPRL3,SIX1,SHH,DLL4,MYLK,LTBP1,GJA5,ZMIZ1,LUZP1,VEGFA,ENG,WNT11,HEY2,SMAD7,FGF8,PLXND1,PROX1
GO:0086019	cell cell signaling involved in cardiac conduction	GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION	0.468854317702012	1.47566516537391	0.0525256999427865	0.388574738477845	21	ANK2,SCN5A,RYR2,RNF207,GJA1,PKP2,CACNA1C,GJA5,KCNA5
GO:0043666	regulation of phosphoprotein phosphatase activity	GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY	0.351916208909639	1.38861095818722	0.0526945039257673	0.388968640820467	55	PPP2R5C,PPP2R3A,ROCK2,CALM3,TSC1,DRD2,AKAP6,JAK2,CD300A,PPME1,AGTR2,CALM1,IKBKB,TNF,PPP1R12A,PPP6R1,HTT,PPP1R11,PPP2R2B,NUAK1,PPP1R15A,PPP2R5B,PPP2R1A,PPP2R5E,EIF2AK2,CRY2
GO:0045926	negative regulation of growth	GO_NEGATIVE_REGULATION_OF_GROWTH	-0.238866657064443	-1.23346319971096	0.0531474680597941	0.391453780064042	223	SEMA3F,SEMA3C,BBC3,RBP4,ING1,MT1M,BDKRB1,NPR1,WT1,MT1E,BMP4,WNT5A,TP53TG5,ULK2,SFRP2,WWC1,ADAM15,MT2A,RTN4,CDKN2C,SEMA3A,SEMA3B,GAS2L1,MT1A,TP73,SLIT3,MT1F,CDKN1A,HIF1A,RERG,ST7L,MSTN,FBP1,SEMA3D,STK3,CDK5,NOV,MT1G,PPARG,FGF13,DCUN1D3,MBL2,SEMA3E,SERTAD3,GAL,SEMA4B,ACVR1B,SEMA4A,FSTL4,NKD1,GNG4,MAPK11,HNF4A,ELANE,KCNK2,INHBA,WWC2,SIRT1,RNF6,IL10,BCL2,WNT3,DNAJC2,SH3BP4,NOG,CAMP
GO:0048644	muscle organ morphogenesis	GO_MUSCLE_ORGAN_MORPHOGENESIS	0.337932306052885	1.37548324286071	0.0532826720862419	0.391592738520285	64	UBE4B,RYR2,MYBPC3,BMP10,XIRP2,TCAP,PKP2,TTN,TNNI3,MYH7,EGLN1,DLL4,MYLK,MYL2,TBX20,S1PR1,NKX2-5,RXRA,TNNT2,HEY2,SMAD7,PROX1,MED1,DSP,PTCD2,TGFBR3
GO:0045987	positive regulation of smooth muscle contraction	GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION	-0.413666152854842	-1.44525951888583	0.053401593221087	0.391611683621305	28	NMU,NPNT,NPY2R,TACR1,ADRA1D,PTGS1,F2R,ABAT,EDN1,PAWR
GO:0010758	regulation of macrophage chemotaxis	GO_REGULATION_OF_MACROPHAGE_CHEMOTAXIS	-0.499090992347614	-1.49964284171158	0.0536614931705522	0.392662143504519	16	CSF1,MMP28,C5AR1,RARRES2,C5,CMKLR1,THBS1
GO:0006775	fat soluble vitamin metabolic process	GO_FAT_SOLUBLE_VITAMIN_METABOLIC_PROCESS	-0.404570733519076	-1.43766684476756	0.0539852586378627	0.393058281114476	30	LRP2,CYP26B1,LRAT,CYP11A1,CYP26A1,RBP1,CYP4F11,PLTP,CYP4F2,VKORC1,VKORC1L1,TTPA
GO:2001258	negative regulation of cation channel activity	GO_NEGATIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY	0.422835922128826	1.4451423190955	0.0540639202730575	0.393058281114476	29	OPRL1,DRD4,CALM3,DRD2,CALM1,HAMP,KCNRG,ANK3,FGF12,TRDN,SUMO1,CASQ2,GSTO1,KCNAB1,KCNQ1
GO:0030534	adult behavior	GO_ADULT_BEHAVIOR	0.284630140470899	1.30590245920757	0.054065948947119	0.393058281114476	127	SHANK3,NLGN3,USP46,SCN1A,NRXN1,PREX2,HDAC2,DRD4,PAFAH1B1,APP,PPARA,TSC1,SHANK1,ATP1A2,DRD2,OPRK1,HIPK2,GHSR,RNF180,CHD7,SNCG,PTEN,CLN8,TMOD1,PARK7,NPY,HOMER1,NPC1,EPHA4,CRHBP,FXN,SDK1,FGF12,ATP1A3,GIGYF2,NTF4,NLGN4X,PCDH17
GO:0003382	epithelial cell morphogenesis	GO_EPITHELIAL_CELL_MORPHOGENESIS	-0.364177435101849	-1.40320970777865	0.0542352360880678	0.393208656297144	42	PAX8,WT1,BMP4,MET,GATA3,GRHL2,TNMD,ST14,GDNF,RILPL2,BASP1,FRMD6,ARHGEF26,SIPA1L3,HEG1,RAC1
GO:0010660	regulation of muscle cell apoptotic process	GO_REGULATION_OF_MUSCLE_CELL_APOPTOTIC_PROCESS	0.383735512063821	1.4139157931666	0.0545237751120104	0.393208656297144	40	LRP6,CAMK2A,HAND2,NACA,HMGCR,LIFR,BAG3,GSK3B,JAK2,SIRT4,SIRT5,APOPT1,NKX2-5
GO:0051098	regulation of binding	GO_REGULATION_OF_BINDING	0.244526535398985	1.23720386732957	0.0545603785428033	0.393208656297144	269	PLCL1,TFIP11,P2RY1,PRKACA,TMC8,NRP1,HMBOX1,CYP2D6,EPB41,PDGFB,CSNK2B,HABP4,ZNF304,HDAC2,APP,TIAM1,ADRB2,PPARA,PRMT7,LRRK2,CALM3,LFNG,PIN1,EBF2,HAND2,MFNG,NFIB,HIPK2,GOLGA2,NSD1,SP100,NKX3-1,HDAC4,PEX14,ADD1,GSK3B,RAPGEF2,JAK2,SMARCD3,CSF3,IFIT2,LRPAP1,PLN,AES,FBXO18,MED25,NFATC4,KAT2A,GTPBP4,HIST1H2BA,LHX2,CALM1,IFIT1,EP300,ACD,MITD1
GO:0048568	embryonic organ development	GO_EMBRYONIC_ORGAN_DEVELOPMENT	-0.215656201511939	-1.18608949699121	0.0547159249930031	0.393208656297144	385	KRT8,KRT19,HOXA6,RPL38,RBP4,PLCD1,PAX8,NKX3-2,OSR1,IRX5,TRAF3IP1,KDR,RARA,SPINT1,PDZD7,RDH10,EFEMP1,TGFBR1,IFT57,MFAP2,BMP4,WNT5A,HOXA3,MYO15A,ATP6V1B1,BMP2,T,HOXA7,NEUROG1,GATA3,WNT9A,CEBPB,PTK7,GRHL2,FGFR2,BBS7,TMED2,FOXF1,CYR61,SOX11,CRB2,MTHFD1L,GBX2,ACVR1,OTX1,MBD3,COBL,ATP2B2,CTNNB1,USH1G,CEBPA,NR4A3,WDR19,EGFR,WNT7B,HIF1A,ST14,HMX3,FZD3,PRKRA,STK3,SMAD2,ZIC3
GO:0010821	regulation of mitochondrion organization	GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION	0.260325997253531	1.264565819988	0.0548595826369007	0.393208656297144	193	PARL,BAD,FLCN,DDHD2,FBXW7,GPHA2,C1QBP,DYNLL2,ATPIF1,RMND1,ADRB2,MOAP1,LRRK2,GZMB,ITGAX,RNF31,PPIF,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,GSK3B,SIAH3,HUWE1,SIRT4,CYB5R1,PSMB7,MTG1,KAT2A,LIG3,NMT1,SAE1,APOPT1,TNFSF10,PPP3R1,PPP1R13B,MARCH5,ARIH2,PARK7,HDAC6,PSMD8,BAG4,VDAC1,USP36,PLD6,TMEM102,FAM162A,FXN,BID,DHODH,KCNN3,OPA1,MAPK8,NSUN4,YWHAG,MAP1LC3B,BAK1,AMBRA1,WBP11,TP53BP2,MPV17L2
NA	multicellular organismal macromolecule metabolic process	GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS	-0.313857180493252	-1.34712002118898	0.0548856548856549	0.393208656297144	70	MMP1,ADAMTS3,SERPINH1,COL6A2,ADAM15,PRTN3,MRC2,TNXB,MMP12,AKR1C3,MMP20,HIF1A,MMP26,COL7A1,CTSK,COL6A5,COL12A1,MMP27,MMP19,MMP14,COL11A2,ACACA,COL11A1,FURIN,ADAMTS14,MMP9,COL13A1,COL6A1,ADAMTS2
GO:0001910	regulation of leukocyte mediated cytotoxicity	GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY	0.366374430870395	1.39853820516597	0.054904357831152	0.393208656297144	47	STAT5B,CRTAM,XCL1,CEACAM1,HLA-B,MICA,P2RX7,SH2D1A,LILRB1,IL21,PIK3R6,AP1G1,NOS2,HLA-E,TAP1,IL12RB1,PPP3CB,STX7,RASGRP1
GO:0002717	positive regulation of natural killer cell mediated immunity	GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY	0.49940786245902	1.48359676302566	0.0554047016812974	0.395257034664253	17	STAT5B,CRTAM,SH2D1B,SH2D1A,IL21,AP1G1,HLA-E,RASGRP1,VAV1,LAMP1,IL12B
NA	regulation of cofactor metabolic process	GO_REGULATION_OF_COFACTOR_METABOLIC_PROCESS	0.363884545533108	1.39543399813001	0.055619492896961	0.395257034664253	48	ME1,DLAT,PPARA,DLD,PGAM2,PGAM1,HDAC4,PDHA1,PRKAA2,GCK,PDHX,PDP1,NCOR1,PDHB,P2RX7,PDPR,DDIT4,CBFA2T3,PRKAG1,ACMSD,PDK3,PPARGC1A,PGAM4,ENTPD5,OGT,INSR,ME2
GO:1901863	positive regulation of muscle tissue development	GO_POSITIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	0.348351483151318	1.37975102399474	0.0556427170618649	0.395257034664253	56	TBX2,ADRB2,PIN1,BMP10,NACA,MKL2,GJA1,HMGCR,USP2,AKAP6,DDX39B,SHH,FGFR1,ERBB4,MTOR,TBX5,TBX20,SOX17,CDK1,GPC1,HEY2
GO:1903214	regulation of protein targeting to mitochondrion	GO_REGULATION_OF_PROTEIN_TARGETING_TO_MITOCHONDRION	0.309978486917873	1.33438791218318	0.0556600815302603	0.395257034664253	87	PARL,FBXW7,GPHA2,ATPIF1,LRRK2,ITGAX,RNF31,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,SIAH3,HUWE1,SIRT4,CYB5R1,PSMB7,KAT2A,SAE1,ARIH2,PSMD8,BAG4,USP36
GO:0097164	ammonium ion metabolic process	GO_AMMONIUM_ION_METABOLIC_PROCESS	-0.255228894675738	-1.26156848353878	0.0561646900872678	0.397814438243353	162	SMPDL3B,PLA2G2A,CHDH,HDC,TPH1,APOA2,SMPD3,SHMT1,ACADL,LIPC,DEGS2,NPR1,BCHE,SNCAIP,SLC22A4,FGF7,PEMT,SGPP2,SMPDL3A,SNCA,PLA2G16,SMPD2,PLA2G2D,ATP2B2,GRIN2A,DDC,AKR1C3,SLC6A3,SAT1
GO:2001252	positive regulation of chromosome organization	GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.278902447586577	1.29288548442184	0.0564430244941427	0.397814438243353	137	TET1,SMARCB1,JARID2,HMBOX1,RNF40,ZNF304,PAF1,AKAP8,UBE2N,GOLGA2,EED,PTEN,OBFC1,MAP3K4,SETDB1,KAT2A,ERCC1,GORASP1,MAPKAPK5,EP300,TCP1,ACD,ANAPC11,MAPK1,VEGFA,DLGAP5,SFPQ,CCT3,ATRX,DMRTC2,WBP2,TPR,BCL6,MRE11A,ESPL1,CCT7,CHTOP,AKAP8L,WRAP53,CCT4,PRKCQ,GCG,PKIB,PAXIP1,MAP2K7,RNF20,NSMCE2,SIN3A,SART3,PLK1,PPARGC1A,RPS6KA5,FOXP3,NEK7,TRIM28,ATM,MAPK3,CCT8,OGT,PIWIL2,ATR,C6orf89,DHX36,TNKS,MTF2,TAL1,TGFB1,NAP1L2,DKC1,SLX4,SREBF1,KAT2B
GO:0060260	regulation of transcription initiation from rna polymerase ii promoter	GO_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER	0.451864428581431	1.45692327959912	0.0564453914257375	0.397814438243353	23	PSMC6,TAF1,PSMC5,CREB1,NKX2-5,CTNNBIP1,HEY2,HMGB1,GTF2F2,SRF,PAXIP1,IRF8
GO:0035967	cellular response to topologically incorrect protein	GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN	-0.278935252975648	-1.29892162674318	0.0564929594415694	0.397814438243353	111	KDELR3,SEC63,CUL7,PDIA6,CREB3L1,CALR,SEC61G,SERP2,ATF3,DDX11,SSR1,XBP1,ATP6V0D1,TOR1A,IGFBP1,TBL2,SERP1,EIF2AK3,ATF6,PDIA5,MBTPS2,RNF126,BAX,CREB3L3,DNAJC3,HDGF,DNAJB9,BHLHA15,SEC61A1,SEC31A,NFE2L2,AMFR,ZBTB17,DERL2,ASNA1
GO:0050819	negative regulation of coagulation	GO_NEGATIVE_REGULATION_OF_COAGULATION	-0.348873308250808	-1.38492865678059	0.056857091367814	0.399542733912447	48	VTN,PROCR,C1QTNF1,ANXA5,SERPING1,ANXA2,F2,PLAUR,ADAMTS18,SERPINB2,PROS1,HS3ST5,CD34,ABAT,EDN1
GO:0045762	positive regulation of adenylate cyclase activity	GO_POSITIVE_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY	0.38184717966125	1.40695802427942	0.0573240352652117	0.401984797297297	40	GNAS,ADRB1,VIP,ADRB2,CALM3,GIPR,GLP1R,VIPR2,ADCY7,ADCY5,CALM1,RAF1,ADCY8,ADCY9,ADCY4,ADORA2B,CALCR,CAP2
GO:0098900	regulation of action potential	GO_REGULATION_OF_ACTION_POTENTIAL	0.387215855744297	1.41123358376386	0.057583203844903	0.402962711313812	38	TRPM4,ANK2,CTNNA3,SCN5A,CACNA2D1,RYR2,RNF207,KCNJ2,CAV3,PKP2,NPS,CACNA1C,GJA5,ANK3,SUMO1,ATP2A2,JUP,DSP
GO:1902275	regulation of chromatin organization	GO_REGULATION_OF_CHROMATIN_ORGANIZATION	0.276137895615791	1.28624618442961	0.0581850714020458	0.405938955966853	142	TET1,SMARCB1,PHF2,UHRF1,JARID2,FLCN,TRIP12,RNF40,ZNF304,PAF1,AKAP8,UBE2N,MTHFR,EED,NSD1,HMGA1,KDM5A,UCN,SETDB1,KAT2A,UBR5,TLK2,EP300,GFI1B,AICDA,SETD7,VEGFA,CTCFL,SPI1,MAP1S,BCOR,DMRTC2,WBP2,TPR,BCL6,APOBEC1,MAPK8,ASF1A,UBE2B,CHTOP,HDAC5,GATA2,AKAP8L,GCG,TWIST1,PAXIP1,RNF20,MYOCD,SIN3A,SART3,PPARGC1A,RPS6KA5,FOXP3,TRIM28,GFI1,ATM,ATAD2B,MAPK3,OGT,PIWIL2,MECP2,C6orf89,MTF2,CTCF,TAL1,TGFB1,CAMK2D,NAP1L2,SPTY2D1,SREBF1,KAT2B,SET
GO:0060333	interferon gamma mediated signaling pathway	GO_INTERFERON_GAMMA_MEDIATED_SIGNALING_PATHWAY	0.330148868494161	1.35643203194349	0.0583532891956614	0.405938955966853	67	IRF2,CAMK2A,IRF6,TRIM26,SP100,OAS2,JAK2,CIITA,HLA-B,CAMK2G,OASL,HLA-H,OAS3,IRF1,OAS1,GBP1,CAMK2B,GBP2,TRIM31,PTAFR,NCAM1
GO:0010721	negative regulation of cell development	GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT	-0.227852605862163	-1.20799195013266	0.0583703073939265	0.405938955966853	276	SEMA3F,VASN,SEMA3C,SOX3,TBX6,PAX8,DLX1,NKX6-1,NLGN1,EFEMP1,ID4,BMP4,WNT5A,ULK2,SFRP2,TRIM11,SPOCK1,EFNA5,LPAR1,FOXA1,ITGB1BP1,SOX11,KATNA1,TSPO,RTN4,CALR,SEMA3A,SEMA3B,CTNNB1,TRIM62,STAT3,TP73,TJP2,ISL2,YWHAH,F2,BMP5,MAG,SEMA3D,CERS2,CDK5,DPYSL3,KCTD11,SORL1,FGF13,EIF2AK4,LMX1A,EDNRB,SEZ6,PCM1,CLDN18,CORO1C,SEMA3E,ADCYAP1,GAL,SEMA4B,LRP1,TTPA,RHOA,SEMA4A,NODAL,FSTL4,SRGAP2
GO:0035270	endocrine system development	GO_ENDOCRINE_SYSTEM_DEVELOPMENT	-0.275060549307475	-1.29128039901366	0.0590095090988077	0.4089261389533	116	SOX3,PAX8,NKX6-1,KDM1A,WT1,TGFBR1,BMP4,WNT5A,HOXA3,BMP2,PAX4,DUOX2,GATA3,TG,MAP2K2,TSPO,ANXA1,POU3F2,MEN1,SLC6A3,EIF2AK3,BMP5,ONECUT1,CDH1,ADCYAP1,PDPK1,RFX8,INSM1,GSX1
GO:0042311	vasodilation	GO_VASODILATION	0.438348598077283	1.44317627811363	0.059129030482098	0.4089261389533	25	AGT,ADRB1,ADRB2,GUCY1A3,AGTR2,SOD2,SOD1,ADORA2B,MKKS,PRKG1,ADRB3,BBS2
GO:0048730	epidermis morphogenesis	GO_EPIDERMIS_MORPHOGENESIS	-0.414538031977889	-1.43516901978081	0.0591642987731007	0.4089261389533	27	KRT71,FGF7,FGFR2,KLF4,KRT25,CTNNB1,TMEM79
GO:0010498	proteasomal protein catabolic process	GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS	0.244849756021141	1.23311491686647	0.0597108939675361	0.411541900670269	258	FBXL7,CUL4A,C18orf25,RNF44,PPP2R5C,UBE4B,FBXO6,SIAH1,ANKZF1,RBCK1,RNF187,CDC26,FBXW7,RNF121,PSMD11,EDEM2,RNF111,PSMD2,PSMC6,RAD23A,NEDD4L,MAD2L1,PCBP2,FZR1,BTRC,GSK3B,SIAH3,ANAPC1,SEL1L,MARCH6,PSMC5,PSMB7,HECTD3,PSME4,KIAA0368,DERL3,TRIM13,DNAJB2,PCNP,FBXO31,WWP1,TMUB1,ANAPC11,FBXO45,YOD1,PSMA8,CDK1,PSMD8,RLIM,VCP,PSMB10,APC,PRPF19,FAF1,NPLOC4,PSMD3,PSMB1,CSNK1A1,RNF115,UBR3,PSMA5,PSMB9,UBXN1,MTA1,UBE2B,UBR2,SDF2L1
GO:0016569	covalent chromatin modification	GO_COVALENT_CHROMATIN_MODIFICATION	0.236965998195174	1.21772109008008	0.0597872814699233	0.411541900670269	309	WDR82,GSG2,TRIM16,PHF2,UHRF1,KDM3B,RNF40,HDAC9,PAF1,HDAC2,PRDM2,PRMT7,KDM2B,DYDC1,MEAF6,CREBBP,UBE2N,MCRS1,KAT7,DR1,SUV39H1,TAF1,EED,NSD1,EYA1,BAP1,HELLS,HDAC4,KAT8,WHSC1L1,JAK2,REST,PRKAA2,HUWE1,MED24,KDM5A,SETDB1,KAT6A,SMYD1,KAT2A,EZH2,PPP5C,EZH1,EP300,PHF21A,TET2,ING3,MBD3L1,RBBP5,SETD7,SETD1B,MECOM,HDAC6,CDK1,BRMS1,HSF4,BRD1,ATXN7,ATF2,NAA50,NCOA3,PKN1,CTCFL,LDB1,SFPQ,PRDM9,SETDB2,SPI1,MSL3P1,HDAC11,CRTC2,BCOR,NCOA1,ENY2,BAZ2A,JMJD6,RNF168,SETD3,KDM5C,PCGF2,MTA1,UBE2B,UBR2,SATB1
GO:1902307	positive regulation of sodium ion transmembrane transport	GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORT	0.503750489167048	1.47192619782091	0.0600687668432302	0.412301561717344	16	DRD4,WNK2,ARF1,DMD,FXYD1,GLRX,ANK3,ATP1B2
GO:0006298	mismatch repair	GO_MISMATCH_REPAIR	-0.408140380011068	-1.42595367105045	0.0602202264051018	0.412301561717344	28	PMS2P1,RPA3,PMS1,TP73,RPA2,TREX1,MSH3,XPC,PMS2P3,ABL1,PCNA,PMS2,POLD1
GO:0003002	regionalization	GO_REGIONALIZATION	-0.225056891646955	-1.20083853779933	0.0603122740298348	0.412301561717344	292	SEMA3F,PAX7,SEMA3C,HOXA6,TBX6,PAX8,DLX1,NKX6-1,OSR1,TRAF3IP1,WT1,CYP26B1,CDON,TGFBR1,IFT57,BMP4,WNT5A,SFRP2,HOXA3,BMP2,T,HOXA7,WNT2B,RFX4,FGFR2,TMED2,FOXF1,FOXA1,CRB2,HOXC10,GBX2,SEMA3A,OTX2,OTX1,COBL,CTNNB1,BMPR1B,PLXNA2,FEZF1,EVX1,NLE1,WDR19,MSX2,WNT7B
GO:1990542	mitochondrial transmembrane transport	GO_MITOCHONDRIAL_TRANSMEMBRANE_TRANSPORT	0.362825772960306	1.38499213522726	0.0603876024737523	0.412301561717344	47	ATP5L,MICU1,PRKAB2,ATP5A1,ATP5G2,ATP5D,PRKAA2,ATP5O,ATP5B,ATP5G3,TIMM17B,ACACB,TIMM22,CHCHD4,NDUFA13,TOMM40L,ATP5F1,TOMM40,ATP5H
GO:0035883	enteroendocrine cell differentiation	GO_ENTEROENDOCRINE_CELL_DIFFERENTIATION	-0.464052192555977	-1.46155745694544	0.0609279291020461	0.414621564351547	19	NKX6-1,BMP4,WNT5A,MEN1,BMP5,PDPK1,INSM1
GO:0006865	amino acid transport	GO_AMINO_ACID_TRANSPORT	-0.272634615349331	-1.28420513041828	0.060974426165866	0.414621564351547	119	SLC1A6,PDPN,SLC36A2,SNAP25,SLC1A1,SLC7A3,SLC17A5,SLC6A17,SLC38A2,SLC7A10,SLC17A7,SLC7A8,SLC7A2,PRAF2,SLC25A22,SLC1A4,FOLR3,UNC13B,SERINC2,ARL6IP5,SLC38A1,SLC38A8,STXBP1,CACNB4,SLC6A14,SLC7A4,CLN3,SLC32A1,SLC7A9,SLC3A2,SLC17A6,SLC38A11,GRM2,SLC6A9,PSEN1,SYT1,SLC7A13,SLC6A12,SLC7A11,SH3BP4,SLC38A5,SLC7A14
GO:0071359	cellular response to dsrna	GO_CELLULAR_RESPONSE_TO_DSRNA	0.40163835445967	1.41593374615896	0.0610969387755102	0.414621564351547	33	ADAR,METTL3,NPM1,ZCCHC11,SMAD1,LIN28B,IFIT1,SRRT,TMEM173,HNRNPA2B1,P2RX7,DICER1,NFKB1,SMAD3
GO:0060828	regulation of canonical wnt signaling pathway	GO_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY	0.251305707904303	1.24418857454692	0.0613016825355419	0.415173970653187	223	LRP5,RAPGEF1,TRPM4,BIRC8,PRICKLE1,TMEM88,LRP6,DVL2,PSMD11,DIXDC1,PPP2R3A,LRRK2,PIN1,PSMD2,PSMC6,RNF220,YAP1,CDH2,SOX2,BTRC,GSK3B,DKK3,CHD8,AES,RGS20,PSMC5,PSMB7,PSME4,UBR5,LATS1,SHH,GPRC5B,ANKRD6,FOXO1,DAPK3,NKX2-5,EMD,ZNRF3,PSMA8,FZD6,SOX17,DKK4,PSMD8,PSMB10,APC,LIMD1,SOX9,WNT11,PSMD3,PSMB1,CSNK1A1,NFKB1,SMAD3,SOX7,LGR5,LRRK1,PSMA5,MLLT3,PSMB9,G3BP1,BAMBI
GO:0001816	cytokine production	GO_CYTOKINE_PRODUCTION	-0.276378342152572	-1.28920839049906	0.0616710396456683	0.416836786038794	112	CHI3L1,CMA1,CD55,ADAMTS3,CCL19,IL18,IRAK4,GATA3,S100A12,HIF1A,IRF7,FABP4,LEP,S100A9,ABCA1,IL17F,NLRP3,TLR9,IFNAR1,NOD1,TXK,TLR2,IL25,VTCN1,CEBPE,GPAM,DLG1,SIRT1,PAWR,CD46,TRIM27,HEG1
GO:0018210	peptidyl threonine modification	GO_PEPTIDYL_THREONINE_MODIFICATION	0.3732685170895	1.39041712412716	0.0620938628158845	0.418151247299155	42	GSG2,MARK2,PRKACA,LRRK2,WNK1,HIPK2,TAF1,GSK3B,TGFBR2,GALNT2,MTOR,MAPK1,CDK1,PKN1
GO:0048485	sympathetic nervous system development	GO_SYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT	-0.447535329347811	-1.44887998062417	0.0621139701870403	0.418151247299155	21	SEMA3F,GATA3,SOX11,SEMA3A,CTNNB1,FZD3,GDNF,INSM1,PLXNA4
GO:2000171	negative regulation of dendrite development	GO_NEGATIVE_REGULATION_OF_DENDRITE_DEVELOPMENT	0.426022903320457	1.42995109249848	0.0625423511528671	0.419759586857154	27	NLGN3,HDAC2,KIAA0319,GSK3B,RAPGEF2,PTEN,NFATC4,GORASP1,DNM3
GO:0031116	positive regulation of microtubule polymerization	GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION	0.492431491339863	1.46287197595666	0.0626022913256956	0.419759586857154	17	TUBGCP5,CLASP1,CLIP1,TUBGCP2,CAV3,CDKN1B,TUBGCP6,TUBGCP3
GO:0002715	regulation of natural killer cell mediated immunity	GO_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY	0.416163502883844	1.42233773954813	0.0629893952945042	0.420904303685089	29	STAT5B,CRTAM,HLA-B,MICA,SH2D1B,SH2D1A,LILRB1,IL21,PIK3R6,AP1G1,HLA-E,TAP1,RASGRP1
GO:0050920	regulation of chemotaxis	GO_REGULATION_OF_CHEMOTAXIS	-0.249504325266777	-1.24383229570231	0.0630231042950935	0.420904303685089	172	SEMA3F,SEMA3C,IL16,SCG2,CCL3,CCL19,KDR,PRKD1,WNT5A,PTPN2,MET,CCR6,TNFSF14,ANO6,LPAR1,CALR,SEMA3A,SEMA3B,CXCL1,FGF18,F7,PLXNA2,CCL21,CSF1,ROBO2,ARTN,FGF4,MMP28,SEMA3D,C5AR1,NOV,RARRES2,C5,CMKLR1,SEMA3E,THBS1,SEMA4B,CCL4,SEMA4A,PDGFD,PLXNA4,ELANE,THBS4,F3,CXCL5,SWAP70,PF4,FGF2,WNT3,RAC1,PLXNA1,FGF16,SEMA7A
GO:0035561	regulation of chromatin binding	GO_REGULATION_OF_CHROMATIN_BINDING	0.501017193923117	1.46393968671583	0.0632097388718521	0.42131481394585	16	HMBOX1,ZNF304,EBF2,FBXO18,MED25,NFATC4
GO:0031572	g2 dna damage checkpoint	GO_G2_DNA_DAMAGE_CHECKPOINT	0.40355515292116	1.4128266784275	0.0635209702973903	0.42255254154351	32	BRSK1,FOXN3,TAOK2,MAPKAPK2,TAOK3,FZR1,CDK5RAP3,CDK1,CLSPN,FOXO4,MRE11A,BABAM1
GO:0006029	proteoglycan metabolic process	GO_PROTEOGLYCAN_METABOLIC_PROCESS	-0.300189127580647	-1.31790148525045	0.0639046088637369	0.423202933154221	79	SULF1,LIPC,B3GALT6,BMP2,HS6ST3,EXTL2,SPOCK2,BMPR1B,SULF2,HPSE,B4GALT7,IDUA,CHST8,NDST3,SGSH,GAL3ST4,EXT1,HS3ST5,DCN,EXTL1,CHST3,B3GAT1,DSEL,CYTL1,COL11A1,HS3ST4
GO:0048663	neuron fate commitment	GO_NEURON_FATE_COMMITMENT	-0.315871898380781	-1.33465943024408	0.0639743086200125	0.423202933154221	65	PAX7,DLX1,NKX6-1,GBX1,TGFBR1,BMP4,OLIG1,FOXA1,HOXC10,OLIG3,EVX1,ISL2
NA	inner ear receptor stereocilium organization	GO_INNER_EAR_RECEPTOR_STEREOCILIUM_ORGANIZATION	-0.461203282242351	-1.45258465996302	0.0641643859420479	0.423202933154221	19	PDZD7,GRXCR1,ATP2B2,USH1G
NA	negative regulation of stat cascade	GO_NEGATIVE_REGULATION_OF_STAT_CASCADE	-0.357810946835829	-1.37867903322755	0.0641675261199049	0.423202933154221	42	FLRT3,PTPN2,LRRC4B,SOCS1,FLRT2,LRRC19,FLRT1,PODNL1,DCN,NYX,HNF4A,SOCS3,LRRTM4,HGS,RTN4RL2,NEUROD1,LRRC4C
GO:1900034	regulation of cellular response to heat	GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT	0.329800739309544	1.34696674688028	0.0643699642095241	0.423202933154221	65	POM121,MAPKAPK2,CAMK2A,CREBBP,NUP85,RAE1,BAG3,GSK3B,CHORDC1,CAMK2G,EP300,NUP188,MTOR,CAMK2B,MAPK1,BAG4,AKT1S1,MLST8,TPR,AAAS,POM121C,HSPH1,NUP214,HSP90AB1,RPTOR,NUP35,ATM,RPA1,MAPK3,NUP93,ATR
GO:0009201	ribonucleoside triphosphate biosynthetic process	GO_RIBONUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS	0.382076737423466	1.39250372996861	0.064575579084306	0.423202933154221	38	ATP5L,UCKL1,ATP5A1,ATP5G2,ATP5D,ATP5O,ATP5B,NME6,ATP5G3,ALDOA,NME5,CAD,CHCHD10,ATP5F1,ATP5H,TCIRG1
GO:0051963	regulation of synapse assembly	GO_REGULATION_OF_SYNAPSE_ASSEMBLY	-0.308551350440919	-1.32434663782623	0.0646107646107646	0.423202933154221	70	LRRN1,SLITRK2,NLGN1,AGRN,FLRT3,WNT5A,SLITRK4,LRRC4B,EFNA5,CBLN2,TPBG,FLRT2,SRPX2,FLRT1,CLSTN3,ROBO2,CHRNB2
GO:0010165	response to x ray	GO_RESPONSE_TO_X_RAY	-0.400857578923815	-1.41252543564824	0.0646245714917616	0.423202933154221	29	SFRP2,ANXA1,TP73,CDKN1A,HIF1A,CASP3,BRCC3,XRCC2,XRCC5,THBD,XRCC4
GO:0050885	neuromuscular process controlling balance	GO_NEUROMUSCULAR_PROCESS_CONTROLLING_BALANCE	0.361795920902297	1.3746960694466	0.0648454349388929	0.423469488997561	46	HERC1,NRXN1,DLG4,PAFAH1B1,APP,SHANK1,ABR,GRIN2C,CLN8,ADCY5,POU4F3
GO:0043624	cellular protein complex disassembly	GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY	0.286346372900729	1.292338633532	0.0649168913614799	0.423469488997561	115	PTCD3,AURKAIP1,MRPL4,MRPL16,MRPL41,VPS4A,MRPL14,MICAL3,MRPL19,MRPS15,APEH,MRPL53,PEX14,CFL1,MRPL15,MRPL27,MRPS28,MRPL24,MRPL35,MRPL20,MRPL17,MRPL12,MRPL37,MRPL51,MRPS22,MRPS18B,MRPL39,CFL2,MRPS25,MRPL46,GSPT1,MRPL18,KIF19,MRPS30,MRRF,MRPS17,MRPL28,SYNJ1,NAPB,MRPL30,MRPS7,MRPL54,NAPA,MRPS26,MRPL10,MRPL52,ETF1,MRPS9,DSTN,MRPS18A,AKAP5,VPS4B,MRPS31,N6AMT1,MRPL36,MRPL1
GO:0015804	neutral amino acid transport	GO_NEUTRAL_AMINO_ACID_TRANSPORT	-0.382032271296493	-1.40029786605271	0.0650735130813308	0.423656858024866	34	SLC36A2,SLC1A1,SLC6A17,SLC38A2,SLC7A10,SLC7A8,SLC1A4,SERINC2,SLC38A1,SLC32A1,SLC7A9,SLC3A2,SLC6A9,SLC7A13,SLC38A5,SLC36A4
GO:0086010	membrane depolarization during action potential	GO_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL	0.379058310572606	1.38897838133855	0.0652472527472528	0.423656858024866	39	SCN7A,ANK2,SCN1A,CATSPER2,SCN5A,CACNA2D1,TPCN1,ATP1A2,KCNJ2,SLC8A1,KCNH2,CACNA1C,SCN3A,CACNA1B,CATSPER4,CACNA1E
GO:0048660	regulation of smooth muscle cell proliferation	GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION	0.299576967539903	1.30970885798415	0.065521540379554	0.423656858024866	95	PPARD,PDGFB,STAT5B,NOTCH3,SERPINF2,MFN2,VIP,FLT1,NDRG4,IGFBP3,ESR1,HMGCR,HDAC4,GSK3B,VIPR2,DDX39B,TGFBR2,CX3CL1,ESR2,CDH13,MTOR,S1PR1,TNF,NPY5R,CTNNBIP1,CDKN1B
GO:0061640	cytoskeleton dependent cytokinesis	GO_CYTOSKELETON_DEPENDENT_CYTOKINESIS	-0.366959889531004	-1.3803067372753	0.0657918308849875	0.423656858024866	38	CUL7,KIF20A,CEP55,ACTR3,ANLN,KIAA0196,FMN2,KIF4A,ZNF365,AURKB,SNX33,RHOA,GTPBP8,SPAST,STMN1
GO:0032350	regulation of hormone metabolic process	GO_REGULATION_OF_HORMONE_METABOLIC_PROCESS	-0.414935407643767	-1.42219891134912	0.0659657303741504	0.423656858024866	26	PAX8,KDM1A,FFAR3,BMP2,GATA3,AKR1C3,HIF1A,BMP5,DUOXA1
GO:0009303	rrna transcription	GO_RRNA_TRANSCRIPTION	0.508054725609972	1.45987872998517	0.066079295154185	0.423656858024866	15	NPM3,BRF1,GTF3C5,GTF3C1,TAF1B
GO:0090407	organophosphate biosynthetic process	GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS	0.224734415671784	1.18894250862206	0.0661618112974268	0.423656858024866	410	TK1,ATP5L,PIK3C2B,IDI2,CHAT,ME1,PANK3,PIK3R1,MTMR1,PPARD,LPIN1,DDHD2,CMPK2,GUCY1A2,PCYT1A,UPP2,FITM2,TAZ,AK1,CHPT1,PPAT,CRYL1,FADS1,PLD1,UCKL1,GUCY1B3,ATP5A1,LCAT,PLA2G5,ATP5G2,SERINC5,HAAO,ATP5D,INPP5J,OAS2,PIP5K1B,ARF1,GUCY1A3,INPPL1,LPCAT4,AGPAT3,COASY,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,MVD,AK4,PRPSAP2,INPP5D,NMNAT3,ADCY7,PIK3C3,FITM1,PIP4K2C,NPR2,IRS1,ATP5O,ADCY5,IP6K3,GGPS1,PIKFYVE,CKM,ATP5B,PI4K2A,NFS1,GPAA1,PIP4K2B,FGFR1,AGPAT1,CDS2,NME6,ADA,ATP5G3,GUCY2C,MBOAT2,IPMK,ADCY8,ADCY9,OAS1,ADSSL1,PCYT1B,PANK4,PIK3R5,PIK3C2G,ADCY4,DGKE,MOCS2,MPPE1,ALDOA,PLD6,PIGM,GPHN,LCLAT1,RFK,NME5,PTAFR,IDI1,ACACB,PIP5K1C,GAB1,SGMS1,FGF6,TPK1,VAC14,CAD,DHODH,FGF8,MTMR14,SLC27A1,SACM1L,INPP5F,CHKA,IMPDH1,TAMM41,MBOAT1,DPM2,SCP2,PLA2G4D,NMNAT2,PIGS,ADM,MTMR2,CHCHD10,PCYT2,UMPS,PIK3R6,TKT,CDIPT,ISYNA1,PIK3R2,PIK3CB
GO:0016338	calcium independent cell cell adhesion via plasma membrane cell adhesion molecules	GO_CALCIUM_INDEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES	-0.459468654492786	-1.44712135612981	0.0661844563186933	0.423656858024866	19	CLDN1,CLDN15,CLDN9,CLDN16
GO:0050729	positive regulation of inflammatory response	GO_POSITIVE_REGULATION_OF_INFLAMMATORY_RESPONSE	-0.276643390385298	-1.28288363019808	0.0662542263146536	0.423656858024866	108	PLA2G2A,C3,CNR1,CCL3,TNFSF11,MAPK13,IL17B,IL18,FFAR3,WNT5A,OSMR,RPS19,AGTR1,S100A12,IL6ST,LPL,TNFRSF1A,FABP4,IL17RC,TLR10,VAMP8,S100A9,IL17F,NLRP12,TLR9,CREB3L3,CCL4,TLR2,FCER1A,CCL18,IL17RB,PTGER4
GO:2001236	regulation of extrinsic apoptotic signaling pathway	GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.273089117684278	1.27204502246002	0.0663043111306168	0.423656858024866	142	MADD,AGT,TRAF1,TMC8,NRP1,RBCK1,CFLAR,BIRC6,YAP1,LGALS3,ARHGEF2,SP100,EYA1,CTNNA1,FEM1B,PTEN,STRADB,AGTR2,BCL2L14,CX3CL1,AR,RAF1,FGFR1,STX4,TNFRSF10B,TNFSF10,G0S2,DAPK3,IL4,TNF,CSF2,PARK7,MAL,TIMP3
GO:0050974	detection of mechanical stimulus involved in sensory perception	GO_DETECTION_OF_MECHANICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION	-0.4309154907054	-1.42927068439803	0.0663301141352063	0.423656858024866	23	PDZD7,PIEZO2,ATP2B2,TMC2,KCNA1,PAWR,TRPA1,HTR2A,COL11A1,CHRNA10,IGF1,NTRK1
GO:0007292	female gamete generation	GO_FEMALE_GAMETE_GENERATION	-0.290205850350053	-1.29903721850643	0.0665977589325566	0.424560713195048	88	DMRT1,FSHR,INSL3,REC8,CTNNB1,BMPR1B,YBX2,PAQR5,PARN,LEP,CCNB1,KIAA0196,FBXO5,HPGD,TAF4B,FMN2,IL1R1,DYNLL1,NPM2,AURKC,AFP,FSHB,GPR149,FOXO3,PABPC1L,RPS6,SIRT1,FOXL2,IL4R,MMP19,BCL2,PLA2G4A,NRIP1,RPS6KA2
GO:1901861	regulation of muscle tissue development	GO_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	0.297177001330138	1.30367668043787	0.0667277631760963	0.42458535132465	97	TBX2,HDAC9,PRICKLE1,ADRB2,PIN1,DDX17,CAPN3,BMP10,NACA,MKL2,GJA1,HMGCR,HDAC4,USP2,AKAP6,CAV3,DDX39B,TGFBR2,SIX1,SHH,FGFR1,LUC7L,ERBB4,MTOR,TBX5,TBX20,NKX2-5,SOX17,CDK1
GO:0000132	establishment of mitotic spindle orientation	GO_ESTABLISHMENT_OF_MITOTIC_SPINDLE_ORIENTATION	0.472122789402701	1.4447511194439	0.0673226595508117	0.427562400090626	19	NDE1,CENPA,PAFAH1B1,ARHGEF2,EYA1,GPSM2,PAX6,HTT
NA	regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process	GO_REGULATION_OF_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS	0.299470006423677	1.30669928878109	0.0675352576319346	0.427928880604371	94	CDC26,FBXW7,PSMD11,PSMD2,PSMC6,MAD2L1,GOLGA2,FZR1,SUFU,BTRC,CAV3,PTEN,CDK5RAP3,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,ANAPC11,PSMA8,CDK1,PSMD8,PSMB10,PSMD3,PSMB1,PSMA5,PSMB9,EGF,PSMD6,PSMB3,PSMB6,PSMD1,PLK1,UBE3A,CDKN2A,PSME2,PTK2,UBE2D1
GO:0046653	tetrahydrofolate metabolic process	GO_TETRAHYDROFOLATE_METABOLIC_PROCESS	-0.466071177489385	-1.4473625399797	0.0676346299707444	0.427928880604371	18	SHMT1,ALDH1L1,GART,MTHFD1L,TYMS,DHFR,FTCD,ALDH1L2
GO:0046466	membrane lipid catabolic process	GO_MEMBRANE_LIPID_CATABOLIC_PROCESS	-0.436631509158433	-1.43147508520132	0.0678689457442385	0.428605762429844	22	SMPDL3B,SMPD3,SMPDL3A,SGPL1,NEU1,NEU2,GBA3,ACER1,CYP1B1
GO:0051351	positive regulation of ligase activity	GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY	0.293381277808106	1.29813816424256	0.0680706708913073	0.429068977571198	102	DCUN1D2,CDC26,FBXW7,PSMD11,PIN1,PSMD2,UBE2N,PSMC6,MAD2L1,GOLGA2,PINK1,FZR1,BTRC,PTEN,ANAPC1,PSMC5,PSMB7,PSME4,GORASP1,ANAPC11,PSMA8,CDK1,PSMD8,PSMB10,TRIB3,PSMD3,PSMB1,PSMA5,PSMB9,CDC20B
GO:0035249	synaptic transmission glutamatergic	GO_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC	-0.436118027415148	-1.42979166037557	0.06819723796809	0.429068977571198	22	P2RX1,SLC17A7,CLSTN3,CDK5,SLC1A4,GRID2,UNC13B,CDH8,GRIK2,CACNB4,SHC3
GO:0032006	regulation of tor signaling	GO_REGULATION_OF_TOR_SIGNALING	0.330551719386679	1.34101381301469	0.0685986404192041	0.430789223229554	63	GNA12,FLCN,RRAGB,RRAGD,MIOS,TSC1,TSC2,FNIP1,PRKAA2,NPRL3,TMEM127,MAPKAPK5,FAM83D,WDR59,RNF152,PDCD6,HTR6,DEPDC5,AKT1S1,MLST8,EPM2A,UBR2,DDIT4,CRYBA1
GO:0030100	regulation of endocytosis	GO_REGULATION_OF_ENDOCYTOSIS	-0.243862302431095	-1.22842777543534	0.0693066808005856	0.433884748227595	185	VTN,RSPO1,C3,C4A,C2,APOC1,CCL19,NLGN1,PRKD1,WNT5A,C4BPA,RUFY1,SNAP91,ANO6,ANGPT1,ALOX15,LMAN2,PROM2,SNCA,CALR,ANXA2,PRTN3,C4BPB,TOR1A,CALY,PYCARD,CCL21,TULP1,ADIPOQ,DAB2,ABCA7,PPARG,MAGI2,NR1H3,PROS1,MBL2,PICK1
GO:0035384	thioester biosynthetic process	GO_THIOESTER_BIOSYNTHETIC_PROCESS	0.359514903947756	1.36602901473264	0.0694644140905823	0.433884748227595	46	DLAT,AGK,ACOT6,ACOT2,DLD,PDHA1,ACOT11,ACSF2,ELOVL6,PDHX,ACOT8,PDHB,ACACB,GCDH
GO:0014743	regulation of muscle hypertrophy	GO_REGULATION_OF_MUSCLE_HYPERTROPHY	0.388730978577604	1.38891852930761	0.0694782766769678	0.433884748227595	35	AGT,PDE5A,AKAP1,PIN1,BMP10,GSK3B,AKAP6,CAV3,DDX39B,AKAP13,MTOR
GO:0016125	sterol metabolic process	GO_STEROL_METABOLIC_PROCESS	0.28392497030766	1.28279377953928	0.0697479852479169	0.43469646430954	116	IDI2,CNBP,LRP5,LSS,CYP4V2,PPARD,CUBN,APP,VLDLR,LDLR,CYP17A1,LCAT,PCSK9,CEL,HMGCR,MVD,CYP51A1,PRKAA2,CYB5R1,CYP7B1,CLN8,MBTPS1,GGPS1,MSMO1,INSIG1,IL4,HMGCS2,RXRA,CELA3A,HMGCS1,SQLE,FDX1,NPC1,CETP,IDI1,APOL1,APOL2,FDFT1
GO:0002440	production of molecular mediator of immune response	GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	-0.3184425963195	-1.32931137749685	0.0699878381789394	0.43469646430954	61	GCNT3,CD55,TCF3,PMS2P1,TRAF3IP2,HLA-DRB5,KLK3,EXOSC6,FAS,MSH3,POLQ,RNF8,POU2F2,TLR2,HLA-DRB1,DLG1,SIRT1,NBN,SWAP70,PMS2,VPREB1
GO:0009791	post embryonic development	GO_POST_EMBRYONIC_DEVELOPMENT	-0.293043308299675	-1.2980713464918	0.0701258008698499	0.43469646430954	83	SEMA3C,MORC3,EFEMP1,TGFBR1,MFAP2,BMP4,PYGO1,GATA3,HELT,FGFR2,KLF4,SGPL1,SERP1,EMX1,SOX6,SLC18A2,SMAD2,NKX2-3,CYP1A2,BAX,ACVR2B,PYGO2,PSEN1,GABRG2,TAL2,BCL2,CSRNP1,HEG1,PRDM1
GO:0000002	mitochondrial genome maintenance	GO_MITOCHONDRIAL_GENOME_MAINTENANCE	0.461579921498068	1.43279255032396	0.0702257586972613	0.43469646430954	20	SLC25A36,SLC25A4,DNAJA3,LIG3,POLG,MRPL17,LONP1,MRPL39,OPA1
NA	cofactor biosynthetic process	GO_COFACTOR_BIOSYNTHETIC_PROCESS	0.268725387411966	1.26067084750522	0.070352688027435	0.43469646430954	149	COX15,ME1,PANK3,DLAT,CIAO1,AGK,ATPIF1,ACOT6,ACOT2,DLD,LIPT2,HAAO,FPGS,COASY,PDHA1,LIAS,ACOT11,NMNAT3,COX10,ACSF2,COQ9,NFS1,ELOVL6,ALAD,PDHX,PANK4,ACOT8,MOCS2,PDHB,GPHN,RFK,ACACB,GCDH,FXN,TPK1,NDUFA9,MMS19,NMNAT2,CIAPIN1,COQ2,SPR,NFE2L1,NARFL,QDPR,COQ5,ACSS1,SLC25A38,RSAD1,ELOVL7,FECH
GO:0050710	negative regulation of cytokine secretion	GO_NEGATIVE_REGULATION_OF_CYTOKINE_SECRETION	-0.358496765774694	-1.36514720930448	0.070481522956327	0.43469646430954	40	APOA2,EZR,TNFRSF21,ANXA4,ANGPT1,CIDEA,ANXA1,NLRP3,NLRP12,CD34,PTGER4,BANK1,IL10,TRIM27,GAS6,IFNA2,FN1,NR1H4
GO:0051339	regulation of lyase activity	GO_REGULATION_OF_LYASE_ACTIVITY	0.312410063854318	1.3162952468638	0.0706402540662888	0.43469646430954	77	GNAS,ADRB1,DRD4,VIP,ADRB2,CALM3,DRD2,GIPR,FTMT,GLP1R,VIPR2,ADCY7,ADCY5,GUCA1C,CALM1,RAF1,P2RY13,ADCY8,ADCY9,CCR2,GABBR1,PARK7,ADCY4
GO:0043484	regulation of rna splicing	GO_REGULATION_OF_RNA_SPLICING	0.303187809622635	1.30515556838926	0.070694400891955	0.43469646430954	87	PIK3R1,AKT2,C1QBP,SNRNP70,ACIN1,RBM20,RBM10,SF3B4,CELF1,SRSF4,CDK12,TIA1,AHNAK,SFSWAP,SETX,THRAP3,HNRNPA2B1,RNPS1,PRPF19,RBFOX1,JMJD6,RBM5,RBM8A,PQBP1,RBM42
GO:0001763	morphogenesis of a branching structure	GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE	-0.249373979349385	-1.23588456895208	0.0707715318459429	0.43469646430954	165	SEMA3C,WNT6,PAX8,SPINT1,WT1,RDH10,AREG,BMP4,WNT5A,SFRP2,BMP2,MET,NPNT,FGF7,KRAS,GRHL2,FGFR2,FOXF1,FOXA1,GBX2,SEMA3A,ACVR1,CTNNB1,DLG5,CSF1,MSX2,ST14,RSPO2,GDNF,TIMELESS,SEMA3E,BAX,EPHA2,WNT9B,PPP1CA,PKD2,GNA13,MYC,EDN1,MYCN,DLG1,ADAMTS16,SOCS3,HOXB13,IL10,MMP14,BCL2,FGF2,DDR1,PLXNA1,NOG,PRDM1
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION	-0.273833686816272	-1.27315850700507	0.0709576515880655	0.43469646430954	110	SEMA3F,VASN,SEMA3C,NLGN1,WNT5A,ULK2,SFRP2,EFNA5,FOXA1,ITGB1BP1,RTN4,SEMA3A,SEMA3B,CTNNB1,TRIM62,YWHAH,BMP5,MAG,SEMA3D,CDK5,FGF13,CORO1C,SEMA3E,SEMA4B,RHOA,SEMA4A,FSTL4
GO:1901380	negative regulation of potassium ion transmembrane transport	GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT	0.469299927789025	1.43611283176126	0.0710288340375065	0.43469646430954	19	NEDD4L,CAV3,KCNH2,KCNRG,ANK3,SUMO1,CASQ2,ACTN2,KCNAB1,KCNQ1,CAB39
GO:0009451	rna modification	GO_RNA_MODIFICATION	0.291994575413863	1.29200235587107	0.0716868714698994	0.437360941562973	102	ADAR,METTL3,NSUN2,CDK5RAP1,ALKBH8,CTU1,TARBP1,TRMT2B,ADARB1,KIAA1429,TYW5,HENMT1,METTL1,METTL2B,OSGEP,TRMT1L,ALKBH5,FTSJ3,TRMT1,TFB2M,DUS1L,FTO,DUS4L,EMG1,METTL16,APOBEC1,NAF1,PUS1,URM1,NSUN4,YRDC,METTL15,PUS10,LCMT2,TRUB1,AARS2,NSUN3,OSGEPL1,WDR4,RPUSD3,MEPCE,MRM1
GO:0006397	mrna processing	GO_MRNA_PROCESSING	0.225572106950243	1.18687297628893	0.0718127273292505	0.437360941562973	388	TFIP11,SF3A2,ADAR,RALY,METTL3,PRKACA,DGCR14,SNRNP35,RBM28,C1QBP,PAF1,SNRNP70,NCBP1,ACIN1,APP,HNRNPM,PRMT7,CELF2,PRPF6,NOVA2,SNRNP200,SPEN,LGALS3,PRPF3,DHX8,PCBP2,RBM20,WDR33,QKI,ADARB1,RBM10,KIAA1429,RAVER2,SNRPA,SF3B4,RBM17,SNRPN,TUT1,CELF1,SCAF11,CLP1,DDX39B,LSM5,PAN2,SRSF4,CDK12,CNOT6L,GTF2H3,PDCD7,PRPF39,KHDRBS1,HNRNPH3,CPSF1,DDX47,LUC7L,SFSWAP,POLR2I,SETX,CTNNBL1,THRAP3,AICDA,LSM4,SYMPK,NCBP2,SRRT,XAB2,SMN1,PRPF31,HNRNPA2B1,RNPS1,AQR,SRSF1,ALKBH5,SNRPC,PRPF19,GTF2H5,PAPOLG,SFPQ,SF3B3,RBFOX1,U2AF1L4,CD2BP2,HTATSF1,SF1,LSM6,YBX1,JMJD6,SRRM2,APOBEC1,DHX38,DDX20,GTF2F2,RBM5,POLR2C,RBM8A,CPSF6,SMNDC1,CHTOP,KIN,AKAP8L,PQBP1,DDX23,WBP11,PSPC1,FUS,PRPF4B,SUGP2,PTCD2,WDR77
GO:0044088	regulation of vacuole organization	GO_REGULATION_OF_VACUOLE_ORGANIZATION	0.380386525929289	1.37778318920595	0.071854010898492	0.437360941562973	37	LRSAM1,UBQLN4,ADRB2,LRRK2,CALCOCO2,PINK1,RAB1B,RAB3GAP1,PIP4K2C,PIKFYVE,PIP4K2B
GO:0006895	golgi to endosome transport	GO_GOLGI_TO_ENDOSOME_TRANSPORT	0.502809929336502	1.44480797847597	0.0720273611033662	0.437624724682185	15	VPS13A,KIF16B,TGOLN2,SORT1,GBF1,EPS15,RAB14,VPS13C,KLHL20
GO:0001508	action potential	GO_ACTION_POTENTIAL	0.301121534720811	1.30132250184888	0.0721853958974894	0.437794671335044	89	SCN7A,ANK2,SCN1A,KCNMB3,CATSPER2,SCN5A,CACNA2D1,RYR2,TPCN1,NEDD4L,ATP1A2,KCNJ2,GJA1,AKAP6,CAV3,DMD,PKP2,SLC8A1,KCNH2,CACNA1C,GJA5,KCNA5,SCN3A,CACNA1B,ANK3,GJC1,CATSPER4,FGF12,CACNA1E
GO:0031032	actomyosin structure organization	GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION	0.316840154600452	1.31884534954863	0.0730543771014136	0.442268045545608	72	OBSCN,LDB3,CFLAR,LIMCH1,CAPN3,BMP10,LMOD1,LMOD3,OBSL1,TCAP,PRKAR1A,MYPN,TTN,CDC42BPA,TMOD1,MYL2,NKX2-5,FHOD3,PHACTR1,EPB41L4B,MYLK3,CFL2,PROX1,SRF,SORBS1,CASQ2,ACTN2
GO:0072594	establishment of protein localization to organelle	GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE	-0.217954895483736	-1.17644864256326	0.0736765262531769	0.444936694883431	321	GDF5,RPL24,LRWD1,SRP72,RPL38,BBC3,PEX10,RPL35,PEX5L,SEC63,RPL30,RGPD3,RPL9,AP3M1,RPL3,RPS3A,RPS19,TSPO,SEC61G,RPS27,TIMM10,RPL4,IPO5,TIMM9,RPS11,RPL7A,RPS4Y1,VPS25,CTNNB1,SLC25A6,STAT3,MTX1,TOB1,RPS8,AKR1C3,RPL18,KPNA7,SPRN,RAB3GAP2,SNF8,RPS24,RPL18A,UBA52,RAB10,RPL15,RPS16,RPL5,HK2,RPL10A,RPS3,SORL1,NUP50,TOMM34,RPL22,FGF9,SRP54,GCC2,SPCS1,RPS29,OPRD1,RPL26,RPL19,TOMM5,SRP14,BAX,SNX16,RPS28,F2R,RPS5,HSP90AA1,RPS17,MFF
GO:0007586	digestion	GO_DIGESTION	-0.267161782292161	-1.26043405642458	0.0738433948089087	0.444936694883431	120	GCNT3,CTSE,SERPINA3,MUC2,NMU,RBP4,EZR,SCTR,LIPC,AQP1,SSTR2,NPC1L1,AMY2A,HTR3A,MUC6,TJP2,FABP2,LEP,LIPM,SST,TLR9,KCNN4,FABP1,TFF3
GO:0046686	response to cadmium ion	GO_RESPONSE_TO_CADMIUM_ION	-0.35643939692352	-1.35731279735485	0.0740425531914894	0.444936694883431	40	SLC34A1,DTYMK,MT1E,MT1A,CTNNB1,CAT,AKR1C3,MT1F,STAR,MT1G,SPARC,CYP1A2,CYB5A,GPAM
GO:0045948	positive regulation of translational initiation	GO_POSITIVE_REGULATION_OF_TRANSLATIONAL_INITIATION	0.451266520846723	1.42030959291757	0.0741376446486905	0.444936694883431	21	METTL3,DDX3X,EIF2B5,KHDRBS1,YTHDF2,TNF,RXRA,IMPACT,POLR2G,RPS6KB1,PPP1R15A,CCL5
GO:0010817	regulation of hormone levels	GO_REGULATION_OF_HORMONE_LEVELS	-0.206963757491937	-1.15363169518093	0.0741589775918391	0.444936694883431	443	CMA1,CFTR,PRKCA,NMU,RBP4,SMPD3,CNR1,HSD17B6,TNFSF11,SCG5,PAX8,NKX6-1,KDM1A,SNAP25,NMB,CYP26B1,UBE2Q1,RDH10,LRAT,ARL2BP,CPA3,FFAR3,SRD5A3,CYP11A1,ILDR2,BMP2,RETN,FDX1L,DUOX2,CYP26A1,GATA3,TG,EFNA5,HLA-DRB5,FOXA1,C1QTNF1,UGT2B7,SOX11,ANXA5,SYBU,ANXA1,TACR1,AGTR1,FDXR,PCSK1N,SGPL1,SLC25A6,BRSK2,AKR1C3,STXBP3,DGAT2,PCSK1,SERP1,ACVR1C,STAR,RDH8,HIF1A,SNAP23,CHST8,CYP21A2,PCLO,EIF2AK3,RBP1,HCAR2,ADIPOQ,BMP5,LEP,DUOXA1,SLC18A2,RDH13,SMAD2,MME,VAMP8,NNAT,NOV,POMC,RAPGEF3,SLC16A1,ITPR3,GPR119,STARD5,KCNB1,SLC30A8,PTGS1,STXBP5L,RETSAT,ADCYAP1,GAL,ACVR2B,CARTPT,CYB5R4,HSD17B14,ABAT,SLC2A2,TMF1,AFP,FSHB,SLC2A1,EDN1,NDUFAF2,HLA-DRB1,AKR1B15,HNF4A,PTGER4,TRERF1,PLB1,HSD3B2,INHBA
GO:1902235	regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway	GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	-0.408566859475469	-1.4003705927603	0.0743241757033192	0.444936694883431	26	BBC3,PTPN2,CREB3L1,TXNDC12,XBP1,EIF2AK3,MAGEA3
GO:0045600	positive regulation of fat cell differentiation	GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION	-0.349773319328381	-1.35407810876795	0.0744204869932774	0.444936694883431	43	ZBTB7C,TPH1,KLF5,SFRP2,BMP2,CEBPB,XBP1,CEBPA,STK3,PPARG,RARRES2,LMO3,CMKLR1
NA	dsrna fragmentation	GO_DSRNA_FRAGMENTATION	0.481861597512662	1.43147186905737	0.0745610772206517	0.444986854476443	17	ADAR,METTL3,ZCCHC11,SMAD1,LIN28B,SRRT,HNRNPA2B1,DICER1,SMAD3
GO:0046622	positive regulation of organ growth	GO_POSITIVE_REGULATION_OF_ORGAN_GROWTH	0.378638780236673	1.37145274774667	0.0748049314770896	0.445652034251122	37	TBX2,HLX,PIN1,CACNA2D2,YAP1,BMP10,AKAP6,DDX39B,FGFR1,ERBB4,MTOR,TBX5,TBX20,CDK1,HEY2,ACACB,FGF8,PROX1,MEF2C
NA	protein oligomerization	GO_PROTEIN_OLIGOMERIZATION	-0.209900954989545	-1.15958014277929	0.0753268019989271	0.44703348088214	403	CLDN1,KCTD4,SLC34A1,TRPM3,P2RX1,KCNV2,MLC1,TNFSF11,SHMT1,ACADL,LIPC,NLGN1,TRPV5,TRIM72,TMED10,KCNS2,COLEC12,DPYS,S100A10,KCNA3,ENTPD2,HBE1,SLC1A1,MGST1,COL6A2,HLA-DRB5,C1QTNF1,HIST1H4C,ANXA5,SKIL,RPS19,IMPDH2,ANXA2,KCNG1,EVL,IRAK1,CNGA4,CTNNB1,CAT,TP73,TOR1A,RIPK1,STXBP3,SH3GLB1,SMARCAD1,TAF10,TRADD,KCTD8,SEMG2,EIF2AK3,RIPK3,FBP1,ADIPOQ,ANGPTL4,CHRNB2,CALHM1,DPYSL3,DPAGT1,KCTD11,KEAP1,HIST1H4D,TRPM6,ZBTB1,MAGI2,RYR3,ITPR3,KCNG3,SNX2,FAS,KCNB1,NLRP3,ATL3,KCNA1,HIST1H4E,HIST1H3C,POLQ,STX2,USP16,AQP11,BAX,NOD1,HSD17B10,OAT,ATL1,NPM2,MFF,HM13,MIF,SCARA5,HLA-DRB1,AMFR,IKBKE,THBS4,PEX5,YWHAB,CEP57,SPAST,KCTD1,NELL2,AASS,SYT1,TOR2A,HIST1H3I,TYSND1,ST13,TRPA1
GO:0006833	water transport	GO_WATER_TRANSPORT	-0.451965491984377	-1.42348974035307	0.0755245666623224	0.44703348088214	19	PDPN,AQP1,AQP3,AQP8
GO:0032088	negative regulation of nf kappab transcription factor activity	GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY	-0.318607436947723	-1.321075856832	0.0755582956569393	0.44703348088214	59	PTGIS,DAP,UFL1,TCEAL7,ANXA4,KLF4,IRAK1,CAT,PYCARD,IRAK3,PSMD10,ZNF675,NLRP3,NLRP12,TLR9,CMKLR1
GO:0007164	establishment of tissue polarity	GO_ESTABLISHMENT_OF_TISSUE_POLARITY	-0.467562335818541	-1.42994786822704	0.0755937189081628	0.44703348088214	17	C5orf42,WNT5A,PTK7,FZD3,WNT9B,HNF4A
GO:0051346	negative regulation of hydrolase activity	GO_NEGATIVE_REGULATION_OF_HYDROLASE_ACTIVITY	-0.213169357943685	-1.16598276553079	0.0757008568338741	0.44703348088214	365	VTN,WFDC8,SERPINA3,TIMP1,SLPI,C3,CST2,C4A,LXN,PI3,APOA2,SFN,APOC1,SH2D4A,SPINT1,SSPO,MYO1D,SPINT2,AQP1,SERPINB8,SFRP2,WFDC10B,RIMBP2,WFDC2,TNFSF14,SPOCK1,WNT9A,SERPINH1,CST1,SPINT4,TMED2,CRIM1,CAMSAP3,SERPING1,PPP1R36,CRB2,SNCA,GRXCR1,ANXA1,IPO5,KLF4,CSTB,SERPINA6,PCSK1N,ITIH6,GNAT1,ANGPTL3,NLE1,PTTG3P,SERPINA5,PLAUR,ANGPTL4,ABCA7,MAGEA3,SORL1,SERPINB2,COL7A1,SH3RF1,RAG1,PROS1,HGF,C5,TIPRL,TLR9,RPS6KA1,FABP1,PPP4R4,ADCYAP1,TIMP2,THBS1,SPINK1,PXK,F11R,TRIAP1
GO:0042147	retrograde transport endosome to golgi	GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI	0.331580831466249	1.33112859477716	0.0761275189252586	0.448157081212826	60	UBE2O,DENND5A,RAB6A,ERC1,FAM21C,PIKFYVE,RAB6B,VTI1A,ARL1,BET1L,RAB41,TBC1D10B,RAB9B,DCTN1,GOSR1,CLTCL1,GBF1
GO:0008045	motor neuron axon guidance	GO_MOTOR_NEURON_AXON_GUIDANCE	-0.412048519245435	-1.39771999505948	0.0761574124936829	0.448157081212826	25	SEMA3F,LHX9,LHX4,SEMA3A,PLXNA2,CDK5
GO:0071514	genetic imprinting	GO_GENETIC_IMPRINTING	0.480152832642063	1.42639562132209	0.0765883053117096	0.449906170469833	17	GNAS,PRMT7,EED,GSK3B,ZFP57,CTCFL,DIRAS3,KCNQ1,MECP2,CTCF,CDKN1C
GO:0031018	endocrine pancreas development	GO_ENDOCRINE_PANCREAS_DEVELOPMENT	-0.360447892908098	-1.35581209067182	0.0771005016123253	0.452125938026284	38	NKX6-1,BMP4,WNT5A,PAX4,ANXA1,MEN1,EIF2AK3,BMP5,ONECUT1,PDPK1,RFX8,INSM1
GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR	-0.466078333896977	-1.42540933887679	0.0776701129039235	0.453876802959829	17	TAF9B,KDM1A,MUC1,RRM2B,BDKRB2,TRIAP1,MIF,SIRT1
GO:0032288	myelin assembly	GO_MYELIN_ASSEMBLY	0.497647280896473	1.42997327609437	0.0778081376977267	0.453876802959829	15	ANK2,PIKFYVE,NFASC,DICER1,GPC1,MTMR2
GO:0046834	lipid phosphorylation	GO_LIPID_PHOSPHORYLATION	0.29360370363694	1.28608426072283	0.0779366753704889	0.453876802959829	96	PIK3C2B,PIK3R1,PDGFB,AGK,SMG1,PIP5K1B,IMPA2,FGF1,PI4KB,PIK3C3,INPP1,PIP4K2C,IRS1,PIKFYVE,PI4K2A,PIP4K2B,IP6K2,FGFR1,DGKZ,ERBB4,PIK3R5,PIK3C2G,CERK,EFR3B,FAM126A,CD80,PIP5K1C,GAB1,FGF6,TTC7B,FGF8,EGF,TMEM150A,EFR3A,PIK3R6,PIK3R2,PIK3CB,EREG,GRB2,PIK3CG
GO:0051146	striated muscle cell differentiation	GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION	0.262634293932949	1.24464642607439	0.0781158523326029	0.453876802959829	160	XK,AGT,OBSCN,DNER,LDB3,CFLAR,TSC1,CACNA2D2,CAPN3,BMP10,CDH2,BARX2,LMOD1,LMOD3,GSK3B,CAV3,OBSL1,TCAP,DMD,PRKAR1A,SLC8A1,AKAP13,AGTR2,MYPN,TTN,KAT2A,DYRK1B,SHH,TMOD1,MYL2,MTOR,TBX5,NKX2-5,FLNC,FHL2,RXRA,CDK1,VEGFA,HOMER1,FHOD3,MYLK3,TANC1,HEY2,SORT1,LRRC10,TMEM8C,CFL2,PROX1,TBX3,NOX4,MEF2C,SRF,PLEKHO1,SGCB,PTCD2,P2RX2,CASQ2,ACTN2,SMO,IGFBP5,RARB,MYOCD
GO:0045761	regulation of adenylate cyclase activity	GO_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY	0.328920891366962	1.32550093941709	0.0781773390284104	0.453876802959829	61	GNAS,ADRB1,DRD4,VIP,ADRB2,CALM3,DRD2,GIPR,GLP1R,VIPR2,ADCY7,ADCY5,CALM1,RAF1,P2RY13,ADCY8,ADCY9,CCR2,GABBR1,ADCY4
GO:0045637	regulation of myeloid cell differentiation	GO_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	-0.24914104586521	-1.2276238097805	0.0782081240988415	0.453876802959829	159	PRKCA,CCL3,TNFSF11,KDM1A,RARA,PTPN2,HOXA7,CEBPB,FSHR,HIST1H4C,LEO1,GAS2L1,CTNNB1,TJP2,RIPK1,CSF1,HIF1A,IL20,IRF7,TFE3,ADIPOQ,LEP,HIST1H4D,SCIN,FAS,SLC9B2,ZNF675,CLDN18,IL5,HIST1H4E,HMGB2,CARTPT,ACVR1B,HOXB8,MAFB,SENP1,FSHB,MYC,FOXO3,TESC,MAPK11,RASSF2,TRIB1,INHBA
GO:0031342	negative regulation of cell killing	GO_NEGATIVE_REGULATION_OF_CELL_KILLING	0.487425058796246	1.42422435103319	0.0790818697147105	0.456931366742301	16	CEACAM1,HLA-B,IL4,MICA,LILRB1,HLA-E,TAP1,PPP3CB,HLA-A
GO:2001257	regulation of cation channel activity	GO_REGULATION_OF_CATION_CHANNEL_ACTIVITY	0.308932689539627	1.30164382614603	0.0793079851911638	0.456931366742301	77	PRKACA,OPRL1,ANK2,DRD4,CALM3,CACNA2D1,S100A1,DRD2,HRC,RNF207,VAMP2,AKAP6,DMD,PLN,CALM1,AHNAK,HAMP,KCNRG,HOMER1,ANK3,KCNIP2,HTT,FGF12,TRDN,SUMO1,JPH2
GO:0006644	phospholipid metabolic process	GO_PHOSPHOLIPID_METABOLIC_PROCESS	0.229056210883424	1.18849906619482	0.0794166338194718	0.456931366742301	338	PIK3C2B,IDI2,CHAT,PLCB2,PIK3R1,MTMR1,PPARD,LPIN1,DDHD2,PDGFB,PCYT1A,ACP6,FITM2,TAZ,PAFAH1B1,DBI,CHPT1,FADS1,PLD1,PLA2G4C,DRD2,LCAT,PCSK9,PLA2G5,SERINC5,SMG1,INPP5J,PIP5K1B,ARF1,INPPL1,PLCE1,LPCAT4,IMPA2,AGPAT3,ABHD4,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,MVD,INPP5D,ABHD6,PIK3C3,FITM1,INPP1,PIP4K2C,CLN8,IRS1,IP6K3,GGPS1,PLA2G15,PIKFYVE,SMPD4,PI4K2A,LIPG,GPAA1,PIP4K2B,IP6K2,FGFR1,AGPAT1,CDS2,ERBB4,MBOAT2,PCYT1B,PIK3R5,PIK3C2G,DGKE,MPPE1,HADHB,PLA2G4E,PLAA,PLD6,EFR3B,PIGM,CETP,SGPP1,LCLAT1,PLCG1,FAM126A,IDI1,CD80,PIP5K1C,GAB1,SGMS1,FGF6,NAPEPLD,TTC7B,VAC14,HADHA,FDFT1,FGF8,INPP5A,GPCPD1,MTMR14,PNPLA6,EGF,SLC27A1,SACM1L,INPP5F,CHKA,TAMM41,MBOAT1,DPM2,PLA2G4D,PIGS,TMEM150A,APOA5,MTMR2,PCYT2,EFR3A,PIK3R6,CDIPT,ISYNA1,PIK3R2,PIK3CB,PLA1A,EREG
GO:0034199	activation of protein kinase a activity	GO_ACTIVATION_OF_PROTEIN_KINASE_A_ACTIVITY	0.496002403979517	1.42524677577174	0.0795182066581163	0.456931366742301	15	PRKACA,ADCY7,UCN,PRKAR1A,ADCY5,ADCY8,ADCY9,ADCY4
GO:0045986	negative regulation of smooth muscle contraction	GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION	0.495976564920989	1.42517252807745	0.0795367943642075	0.456931366742301	15	ADRB2,ADRA2C,GUCY1A3,DOCK4,SOD1,ADORA2B,PRKG1
NA	regulation of receptor activity	GO_REGULATION_OF_RECEPTOR_ACTIVITY	0.283605918678272	1.27101716640755	0.0795489545190103	0.456931366742301	110	P2RY1,SHANK3,NLGN3,PRKACA,FBXW7,NRXN1,DLG4,APP,CALM3,SHANK1,HRC,ADRA2C,PCSK9,ZGPAT,RASGRF1,AKAP6,CAV3,DMD,PLN,RXRB,TGFA,CALM1,KLHL24,PARK7,SOCS4,HDAC6,NCOA3,LYNX1,PLAU,CRHBP,HTT,TRDN,JPH2,PRKCE,EGF,MED1,NLGN2,MEF2C,STOM,EREG,CASQ2,ACTN2,CACNG7,PPARGC1A,PPP2R5B,HEYL,GSTO1,ADRA2B,SHC1,NCOA2
GO:0042590	antigen processing and presentation of exogenous peptide antigen via mhc class i	GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I	0.322583818181457	1.31749151648892	0.0799026781149174	0.458181285408538	65	PSMD11,PSMD2,PSMC6,PSMC5,PSMB7,PSME4,HLA-B,HLA-H,PSMA8,PSMD8,PSMB10,CYBA,PSMD3,PSMB1,CD36,PSMA5,PSMB9,HLA-F,LNPEP,PSMD6,PSMB3,PSMB6,PSMD1
GO:0006611	protein export from nucleus	GO_PROTEIN_EXPORT_FROM_NUCLEUS	0.404299409597087	1.38178937932351	0.0801832551517696	0.459008225919824	29	ADAR,HSPA9,XPO7,STRADA,GSK3B,STRADB,XPO4
GO:0006400	trna modification	GO_TRNA_MODIFICATION	0.346019357744329	1.33845956418396	0.0804459444903235	0.459730134387825	50	NSUN2,CDK5RAP1,ALKBH8,CTU1,TARBP1,TYW5,METTL1,METTL2B,OSGEP,TRMT1L,TRMT1,DUS1L,DUS4L,PUS1,URM1,YRDC,LCMT2,TRUB1,AARS2,OSGEPL1,WDR4,RPUSD3
GO:0045913	positive regulation of carbohydrate metabolic process	GO_POSITIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS	0.319510425829371	1.31272349383359	0.0806451612903226	0.460087479496993	67	P2RY1,BAD,AKT2,PDGFB,PPARA,GOLGA2,ADCYAP1R1,PRKAA2,IRS1,GCK,KAT2A,FOXO1,ARFGEF1,P2RX7,PTAFR,NFKB1,HMGB1,PTH,PRKCE,EGF,PHKG2,PTH1R,GCG,EPM2AIP1,SORBS1,PPARGC1A,GPLD1,ENTPD5,HRH1,INSR,ARPP19
GO:0042634	regulation of hair cycle	GO_REGULATION_OF_HAIR_CYCLE	-0.432230666434744	-1.39933166957293	0.0808834762871298	0.460195686078907	21	TRPV3,WNT10B,HPSE,MSX2,TRADD,CDH3,GAL
GO:0045822	negative regulation of heart contraction	GO_NEGATIVE_REGULATION_OF_HEART_CONTRACTION	0.461582071265033	1.41249528543003	0.0810355051515825	0.460195686078907	19	PDE5A,ATP1A2,JAK2,PLN,AGTR2,IL2,ATP2A2,NPFF,UTS2,PIK3CG
GO:0090090	negative regulation of canonical wnt signaling pathway	GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY	0.264134715037103	1.24412865858563	0.0810742845647035	0.460195686078907	153	RAPGEF1,PRICKLE1,TMEM88,LRP6,DVL2,PSMD11,PPP2R3A,PSMD2,PSMC6,CDH2,SOX2,GSK3B,DKK3,CHD8,AES,RGS20,PSMC5,PSMB7,PSME4,LATS1,SHH,ANKRD6,FOXO1,NKX2-5,ZNRF3,PSMA8,FZD6,SOX17,DKK4,PSMD8,PSMB10,APC,LIMD1,SOX9,WNT11,PSMD3,PSMB1,CSNK1A1,PSMA5,MLLT3,PSMB9,G3BP1
GO:0007595	lactation	GO_LACTATION	0.37810495181744	1.35996297161241	0.0814149659863946	0.461208569327258	36	ATP7A,STAT5B,PPAT,CCND1,ERBB4,CREB1,NCOR1,VEGFA,USF2,NCOA1,CAD,DHODH,CSN2,CSN3,MED1,XDH,UMPS
GO:0006754	atp biosynthetic process	GO_ATP_BIOSYNTHETIC_PROCESS	0.403594221306232	1.37937923063767	0.0816069505539635	0.461208569327258	29	ATP5L,ATP5A1,ATP5G2,ATP5D,ATP5O,ATP5B,ATP5G3,ALDOA,CHCHD10,ATP5F1,ATP5H,TCIRG1
GO:2000144	positive regulation of dna templated transcription initiation	GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_INITIATION	0.427065290763891	1.39160419527299	0.0816637870823071	0.461208569327258	24	PSMC6,TAF1,PSMC5,SETX,CREB1,NKX2-5,MITF,GTF2F2,FOSL1,SRF,TWIST1,PAXIP1,IRF8
GO:1903825	organic acid transmembrane transport	GO_ORGANIC_ACID_TRANSMEMBRANE_TRANSPORT	-0.278135839923185	-1.26635274252089	0.0825942613232156	0.465682217108783	97	SLC1A6,SLC36A2,EMB,SLC22A4,SLC1A1,SLC7A3,SLC17A5,SLC6A17,SLC38A2,SLC7A10,SLC17A7,SLC7A8,SLC7A2,SLC25A22,SLC1A4,SLC16A1,SLC38A1,SLC13A5,SLC38A8,SLC6A14,SLC7A4,SLC32A1,SLC7A9,SLC23A2,SLC17A6,SLC38A11,SLC6A9,AQP9,SLC16A8,SLC7A13,SLC16A4,SLC6A12,ACACA,SLC7A11,SLC38A5,SLC7A14
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii	GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II	-0.282983241777121	-1.26956871524632	0.0831981187536743	0.466550285670538	89	KIF2C,CTSE,KIF18A,KIF5A,HLA-DRB5,KIF3A,CANX,SEC24D,SEC24A,SEC13,AP1S3,MARCH1,DYNC2LI1,KIF4A,DYNLL1,KIF3C,SPTBN2,SEC31A,DYNC1I1,HLA-DRB1,ACTR1B,DYNC2H1,SH3GL2,AP1S2,KIF2B,HLA-DRA,AP1M1
GO:0048813	dendrite morphogenesis	GO_DENDRITE_MORPHOGENESIS	0.365626124859709	1.34718975982465	0.083249024425495	0.466550285670538	40	SHANK3,PREX2,DLG4,VLDLR,SHANK1,RERE,PTEN,DCLK1
NA	macromolecular complex remodeling	GO_MACROMOLECULAR_COMPLEX_REMODELING	-0.424866423529494	-1.39290382637131	0.0835175417478278	0.466550285670538	22	PLA2G2A,APOA2,APOC1,LIPC,AGTR1,LPL,PLTP,APOM,ABCG1
NA	regulation of smad protein import into nucleus	GO_REGULATION_OF_SMAD_PROTEIN_IMPORT_INTO_NUCLEUS	-0.471093769344706	-1.41551823175494	0.0835335627854623	0.466550285670538	16	TGFBR1,BMP4,DAB2,NOV,NODAL
GO:0035282	segmentation	GO_SEGMENTATION	-0.286778075231784	-1.2738707203973	0.0836096194256362	0.466550285670538	84	SEMA3F,SEMA3C,TBX6,OSR1,WT1,BMP4,WNT5A,SFRP2,T,TMED2,FOXF1,CRB2,SEMA3A,COBL,PLXNA2,NLE1
GO:0032091	negative regulation of protein binding	GO_NEGATIVE_REGULATION_OF_PROTEIN_BINDING	0.308253368316712	1.29579324344177	0.0836565291402699	0.466550285670538	76	TFIP11,TMC8,PDGFB,ADRB2,PPARA,LRRK2,PIN1,GOLGA2,NKX3-1,PEX14,GSK3B,IFIT2,LRPAP1,AES,NFATC4,GTPBP4,IFIT1,MITD1,CTNNBIP1,PARK7
GO:1903363	negative regulation of cellular protein catabolic process	GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS	0.338851129499566	1.32725157970727	0.0838604767520818	0.466550285670538	53	CSNK2A1,N4BP1,MAD2L1,SUFU,CDK5RAP3,TLK2,SHH,OPHN1,PARK7,APC,PBK,BAG6,USP14,KLHL22,TPR,MAD1L1,UBXN1,PLK1,USP44,HSP90AB1,CDKN2A,USP19,ATM,WAC
GO:0030261	chromosome condensation	GO_CHROMOSOME_CONDENSATION	0.402121850907591	1.37434705465378	0.0839067662036615	0.466550285670538	29	HILS1,ACIN1,AKAP8,NCAPH,PRM1,TTN,SMC2,CDK1,NCAPD3,AKAP8L,AIFM1,PAPD7,PHF13
GO:2000738	positive regulation of stem cell differentiation	GO_POSITIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION	0.347556250444433	1.33281782391229	0.0839956842294551	0.466550285670538	48	HDAC2,KDM2B,BCL9L,YAP1,GSK3B,TGFBR2,SOX5,GLIPR2,EZH2,GCNT2,TBX5,NKX2-5,SP7,SOX9,SMAD3,BAMBI,TGFB3,TWIST1,TACSTD2,OLFM1
GO:0042493	response to drug	GO_RESPONSE_TO_DRUG	-0.208351518286364	-1.15102041024453	0.0842203337191903	0.467027418943648	403	ASS1,SLC34A1,SEMA3C,SRP72,SLC47A2,APOA2,PLIN2,ITGA3,NKX6-1,LIPC,CA9,ALDOB,AQP1,BCHE,SFRP2,SS18,TNFRSF11B,PAX4,NNMT,MGST1,CYP2C9,GATA3,PEMT,LDHA,DAD1,NPC1L1,MT2A,TSPO,SNCA,CALR,ANXA1,SOCS1,SLC18A1,XRCC1,SLC22A3,CTNNB1,GK,CAT,STAT3,TP73,MMP12,GRIN2A,DDC,CDKN1A,SLC6A3,LPL,CHUK,STAR,HIF1A,CPS1,LRP8,HTR1B,SLC31A1,EMX1,FBP1,ADIPOQ,TYMS,PRKAR2B,CASP3,CDH3,CCNB1,SLC18A2,PPARG,ABCA1,BDKRB2,SRP54,RAPGEF3,PPM1E,SST,FAS,HMBS,CDH1,BCAR3,CHEK2,BLMH,CYP1A2,CROT,XPC,TGIF1,SRP14,TIMP2,THBS1,BAX,GAL,HMGB2,SLC47A1,PARP4,LOX,ABAT,MDM2,MYC,EDN1,JUNB,NFE2L2,HNF4A,PTGER4,EEF2,INHBA,SOCS3,RPP21,CARD9,RET,TIMP4,ATP1A1,IL10,ABCB5,BCL2,TRPA1,HTR2A,PMS2,ALDH3A1,NTS,PDE4B,BLOC1S3,TERF1,JUN,SRR,GATA6,RAP1A,TLR3,PTPN5,MYO6
GO:0097503	sialylation	GO_SIALYLATION	0.459141377301952	1.40502647558961	0.0845749017863761	0.468222235876549	19	ST6GALNAC4,ST8SIA6,ST3GAL6,ST3GAL3,ST3GAL2,ST6GALNAC3,ST6GAL1,ST3GAL4,ST8SIA4,ST6GAL2,ST6GALNAC1,ST8SIA3,ST3GAL1
GO:0006887	exocytosis	GO_EXOCYTOSIS	-0.22012971886793	-1.17338931600926	0.0849674944047746	0.469623294197818	288	MRGPRX2,SERPINA3,CFTR,STX19,TIMP1,HAP1,P2RX1,CCL3,SYT4,SNAP25,ANXA3,NLGN1,TRIM72,TMED10,ARHGAP44,RAB31,RIMS4,SYTL1,SYT17,SCFD1,TRIM9,POTEKP,SERPING1,MMRN1,RPH3A,PDZD11,EXOC5,SCRN1,C2CD4D,MIA3,BRSK2,NR4A3,STXBP3,TMEM79,PRSS12,SNAP23,PCLO,RAB13,STX11,SYT6,ORM1,VPS33A,CDK5,VAMP8,SPARC,UNC13B,SCIN,LIN7B,RARRES2,PROS1,LAT,HGF,KCNB1,F5,SYT5,STX2,STXBP1,STXBP5L
GO:0048483	autonomic nervous system development	GO_AUTONOMIC_NERVOUS_SYSTEM_DEVELOPMENT	-0.346386574078689	-1.33465985682356	0.085399757858392	0.471238663854668	42	SEMA3F,GATA3,SOX11,GBX2,SEMA3A,CTNNB1,PRLH,FZD3,GDNF,EDNRB,INSM1,NAV2,PLXNA4,RET
GO:0070192	chromosome organization involved in meiotic cell cycle	GO_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE	0.364321169235418	1.34238150698236	0.08557956352074	0.471263487338863	40	SUN1,DMC1,SYCP2,TEX11,RAD21L1,SPO11,SMC2,MLH3,NCAPD3,BAG6,MRE11A,UBE2B,CCDC155,MLH1,MEI1,NCAPD2,PPP2R1A,ATM,MAEL
GO:0015844	monoamine transport	GO_MONOAMINE_TRANSPORT	-0.423350607866039	-1.38793429872504	0.0856842704252479	0.471263487338863	22	P2RX1,SNCA,SLC18A1,SLC22A3,SLC29A4,SLC6A3,SLC18A2,PICK1
GO:0010664	negative regulation of striated muscle cell apoptotic process	GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_APOPTOTIC_PROCESS	0.472558688059047	1.40383560741714	0.0861664930813867	0.472843181603004	17	HAND2,NACA,HMGCR,BAG3,JAK2,SIRT4,SIRT5,NKX2-5,HEY2
GO:0040007	growth	GO_GROWTH	-0.21004571326428	-1.15298937763667	0.0864455398668783	0.472843181603004	377	SEMA3F,GDF5,MATN1,PAX7,TARBP2,LIPC,RARA,FLRT3,RDH10,AREG,BMP4,WNT5A,ULK2,SFRP2,BMP2,NUPR1,FMOD,GAP43,GAS1,FGF7,DUOX2,GATA3,THBS3,HELT,PTK7,GRHL2,FSHR,FGFR2,EFNA5,ADAM15,TMED2,COMP,XRN2,SEMA3A,ANXA1,COBL,XBP1,WNT10B,BMPR1B,IGFBP1,SLIT3,OSTN,CSF1,FLRT1,SLC25A25,MSX2,WNT7B,LEFTY1,EPYC,MSTN,EMX1,BMP5,TYMS,LEP,CCNB1,TM4SF4,SMAD2,CDK5,RSPO2,EMP1,NOV,MAGI2,EIF2AK4,PGLYRP1,SIRT6,EIF4H,GINS4,XRCC2,MYOD1,SOX15,RRAGC,SPTBN2,ACVR2B,TXK,ALKBH1,BNC2,SALL4,SEC61A1,GPR149,EDN1,PYGO2,STIL,RAD51B,FOXO3,CDC42,UNC79,PTPN12,SLC3A2,POU4F2,EMP3,PDLIM5,PLXNB1,LUZP4,INHBA,ABL1,EYS,NBN,G6PC,STRA6,TAL2,FOXL2
GO:1903169	regulation of calcium ion transmembrane transport	GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT	0.284638382390333	1.26523501376774	0.0866340892666644	0.472843181603004	105	PRKACA,OPRL1,ANK2,DRD4,CALM3,CACNA2D1,RYR2,S100A1,CAPN3,XCL1,ATP1A2,DRD2,HRC,CXCL11,AKAP6,CAV3,DMD,CXCR3,PLN,SLC8A1,CALM1,AHNAK,CACNA1C,TSPAN13,CYBA,CXCL9,PLCG1,HTT,TRDN,SUMO1,JPH2,PRKCE
GO:0098727	maintenance of cell number	GO_MAINTENANCE_OF_CELL_NUMBER	0.273054081370302	1.25279071207358	0.0866341661588462	0.472843181603004	127	TET1,CUL4A,LRP5,ZHX2,METTL3,EPAS1,PAF1,ZCCHC11,EPHA1,BCL9L,YAP1,CDH2,SOX2,MED7,MED27,MED24,ZNF358,MED12,SMC1A,EZH2,MED28,RAF1,FGFR1,MED17,POLR2I,FOXD3,FOXO1,SRRT,LDB1,SOX9,CDX2,SPI1,LDB2
GO:0043567	regulation of insulin like growth factor receptor signaling pathway	GO_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	-0.428268684888994	-1.38650489284984	0.0867762282022742	0.472843181603004	21	KIAA1161,TRIM72,IGFBP4,BMP2,IGFBP1,BMP5,CDH3
GO:0015791	polyol transport	GO_POLYOL_TRANSPORT	-0.468416754286991	-1.40747447514541	0.0869969911466112	0.472843181603004	16	AQP1,AQP3,AQP8,AQP11,AQP9,SLC5A11,AQP10
GO:0046596	regulation of viral entry into host cell	GO_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL	-0.400529687317726	-1.37282303407406	0.0870818027846821	0.472843181603004	26	IFITM2,TRIM11,MID2,TRIM62,FCN3,TRIM38,TMPRSS2,HS3ST5
GO:0022617	extracellular matrix disassembly	GO_EXTRACELLULAR_MATRIX_DISASSEMBLY	-0.299052786112435	-1.2835774377737	0.0872256872256872	0.472843181603004	70	MMP1,CMA1,TIMP1,LAMA3,LAMC2,KLK7,HTRA1,ADAM15,MMP12,MMP20,TLL1,CTSK,CDH1,CAPN1,CAPN2,DCN,TIMP2,KLK2,ELANE,LAMB3,MMP19,MMP14,NOXO1,CAPNS2,FURIN,SPP1
GO:0010453	regulation of cell fate commitment	GO_REGULATION_OF_CELL_FATE_COMMITMENT	-0.400466311493681	-1.37260581224555	0.0872357741460088	0.472843181603004	26	PAX7,BMP4,SFRP2,FGFR2,SPDEF
GO:2000104	negative regulation of dna dependent dna replication	GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION	0.480581633589304	1.40422830723464	0.0875383328686925	0.473720302951799	16	FBXW7,FBXO18,ZRANB3,SMC1A,LIG3,MRE11A,TIPIN,BRCA2
GO:0035987	endodermal cell differentiation	GO_ENDODERMAL_CELL_DIFFERENTIATION	-0.349584544804992	-1.33120968253433	0.0878387458006719	0.474486549521696	40	VTN,LAMA3,LEO1,CTNNB1,COL7A1,NODAL,LAMB3,COL12A1,INHBA,MMP14,COL11A1,GATA6,HSBP1,MMP9,EOMES,MIXL1,FN1,COL6A1,LAMB1
GO:0051703	intraspecies interaction between organisms	GO_INTRASPECIES_INTERACTION_BETWEEN_ORGANISMS	0.35355113577366	1.33091218665783	0.0881044574515984	0.474486549521696	44	SHANK3,NLGN3,NRXN1,DLG4,DRD4,SHANK1,VPS13A,PTEN,UCN,CLN8
GO:0035637	multicellular organismal signaling	GO_MULTICELLULAR_ORGANISMAL_SIGNALING	0.278832098598869	1.25620475368873	0.0882031116430159	0.474486549521696	114	PRKACA,TRPM4,CACNA2D4,SCN7A,ANK2,SCN1A,KCNMB3,CTNNA3,PAFAH1B1,SCN5A,CACNA2D1,RYR2,CACNA2D2,ATP1A2,RNF207,KCNJ2,GJA1,CACNG1,PKP2,PLN,SLC8A1,NFASC,KCNH2,CACNA1C,GJA5,KCNA5,S1PR1,SCN3A,SOD1,ANK3,KCNIP2,GJC1,CATSPER4,ATP1A3
GO:0032012	regulation of arf protein signal transduction	GO_REGULATION_OF_ARF_PROTEIN_SIGNAL_TRANSDUCTION	0.489142878372942	1.40553615204158	0.0883659547575234	0.474486549521696	15	FBXO8,ARFGEF2,CYTH1,PSD3,ARFGEF1,IQSEC1,GBF1
GO:0060421	positive regulation of heart growth	GO_POSITIVE_REGULATION_OF_HEART_GROWTH	0.407563012659854	1.36799024341785	0.0886031903008992	0.474486549521696	27	TBX2,PIN1,BMP10,AKAP6,DDX39B,FGFR1,ERBB4,MTOR,TBX5,TBX20,CDK1,HEY2,ACACB,PROX1,MEF2C
GO:0034113	heterotypic cell cell adhesion	GO_HETEROTYPIC_CELL_CELL_ADHESION	0.412193599169703	1.3706318950184	0.0887071636810356	0.474486549521696	26	MADCAM1,CTNNA3,ITGB3,ITGAX,RNASE10,PKP2,NFASC,ITGB2,JUP,DSP,ITGAD
GO:0045026	plasma membrane fusion	GO_PLASMA_MEMBRANE_FUSION	-0.421279277401939	-1.38114354292665	0.0887483311811954	0.474486549521696	22	STX19,SNAP25,SERPINA5,SNAP23,STX11,IZUMO1,STX2,SNAPIN,CATSPER1,ADAM2,NSF
GO:0071696	ectodermal placode development	GO_ECTODERMAL_PLACODE_DEVELOPMENT	0.488701452186563	1.40426772825204	0.0888492351158943	0.474486549521696	15	GNAS,NRP1,TBX2,HDAC2,SIX1,PROX1,TBX3,EDA,NRG3,SIX4
NA	transcription from rna polymerase i promoter	GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER	-0.367415147539613	-1.34672038388052	0.0889486074712388	0.474486549521696	34	POLR2H,TAF1D,TBP,CEBPA,POLR2K,CD3EAP,GTF2H2,POLR1B,UBTF,GTF2H1
GO:0046888	negative regulation of hormone secretion	GO_NEGATIVE_REGULATION_OF_HORMONE_SECRETION	0.309152017425424	1.29005933453362	0.0894460682466458	0.474822794181448	73	BMP8A,PDE8B,NPY1R,DRD2,OPRK1,GHSR,ADRA2C,HMGCR,OSM,PDE4C,REST,SIRT4,UCN,IRS1,GCK,HADH
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	GO_PYRIMIDINE_DEOXYRIBONUCLEOTIDE_METABOLIC_PROCESS	-0.45711722462468	-1.39800354050674	0.089501232858935	0.474822794181448	17	DTYMK,SHMT1,DUT,SMUG1,NEIL2,TYMS,NT5M
GO:1901361	organic cyclic compound catabolic process	GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS	-0.209554102712294	-1.14966797359213	0.0895097875188221	0.474822794181448	376	DNASE1L2,DNASE1,RPL24,HDC,RPL38,SMG9,HSD17B6,AOX1,GSTZ1,MPG,NUDT18,DPYS,ALDH1L1,RPL35,DUT,RPL30,ENTPD2,LRTOMT,RPL9,RPL3,RPS3A,CARNS1,SMPDL3A,NUDT5,RPS19,TAT,XRN2,RPS27,RPL4,CNOT6,RPS11,RPL7A,RPS4Y1,EIF4A2,CAT,RPS8,PABPC1,APOBEC3F,PDE11A,RPL18,YWHAH,SLC6A3,SMUG1,EXOSC2,EXOSC6,NEIL2,RPS24,RPL18A,UBA52,RPL15,UROC1,RPS16,PARN,CASP3,RPL5,EXOSC5,RPL10A,RPS3,AMDHD1,RPL22,RPS29,NT5M,RPL26,RPL19,CYP1A2,GDA,FTCD,HNMT,ALDH1L2,HMGB2,EXOSC10,RPS28,FAH,DNASE2,RPS5,RPS17,DROSHA,HSD17B14,CYP7A1,EXOSC8,RNASE2,POP1,BLVRA,TRERF1,PAPD5,RPL36,NANOS2,CNOT7,RPS6,FOXL2,RPL23A,RPS18,FAU,RPL32,PDE1B,SULT2A1,RPLP0,RPL14,DFFB,PDE4B,RPS15,STS,NEIL1,ITPA,HPD,HINT1,PDE3B,RPS13,RPL28,RPS4X,NUDT9,RPL34,KPNA1,APOE,UPF3B,TATDN1,CYP46A1
GO:0007584	response to nutrient	GO_RESPONSE_TO_NUTRIENT	-0.240322302021381	-1.20590682192143	0.089658647184784	0.474822794181448	180	ASS1,SLC34A1,CDKN2B,C2,CNR1,RARA,BCHE,SFRP2,AQP3,SSTR2,ALPL,TNFRSF11B,PEMT,LDHA,DAD1,TSPO,PKLR,ZNF354A,XBP1,F7,CAT,CP,PIM1,AKR1C3,STAR,ADIPOQ,TYMS,LEP,HLCS,PPARG,SPARC,ABCA1,NQO1,SLC16A1,SST,HMBS
GO:0050820	positive regulation of coagulation	GO_POSITIVE_REGULATION_OF_COAGULATION	-0.40876852286669	-1.37231992957832	0.0898543731906308	0.474822794181448	24	ANO6,F7,HPSE,F2,S100A9,THBS1,F2R,NFE2L2,F3,PSEN1,THBD
GO:0009743	response to carbohydrate	GO_RESPONSE_TO_CARBOHYDRATE	-0.245745227388219	-1.21222971168589	0.0898580273005296	0.474822794181448	160	CMA1,APOA2,KHK,NKX6-1,LIPC,ALDOB,COLEC12,ILDR2,CTGF,LDHA,COL6A2,SLC2A5,SARM1,PKLR,SESN2,XBP1,MEN1,CAT,PRLH,LPL,ACVR1C,STAR,HIF1A,ADIPOQ,CASP3,LEP,SMAD2,SPARC,FAS,HMBS,KCNB1,SLC30A8,IL1R1,APOM,THBS1,ACVR2B,SLC2A2,CYP7A1,MDM2,GPAM,HNF4A,PTGER4
GO:0002790	peptide secretion	GO_PEPTIDE_SECRETION	-0.319663059568046	-1.30124432264278	0.0902894533557504	0.476354702187235	54	SMPD3,UBE2Q1,ILDR2,ANXA1,STXBP3,PCLO,EIF2AK3,LEP,SLC18A2,SMAD2,ABCA1,GPR119,SLC30A8,GAL,ACVR2B,CARTPT,CYB5R4,EDN1
GO:0006103	2 oxoglutarate metabolic process	GO_2_OXOGLUTARATE_METABOLIC_PROCESS	0.454705862370138	1.39145327957601	0.0905233118375213	0.476841107425816	19	IDH3B,STAT5B,DLD,OGDH,IDH2,GOT2,ADHFE1,IDH1,GOT1,DLST,D2HGDH,IDH3G,L2HGDH
GO:0097035	regulation of membrane lipid distribution	GO_REGULATION_OF_MEMBRANE_LIPID_DISTRIBUTION	-0.359400363149747	-1.33587907628627	0.0913831138445083	0.478113753114522	36	ANO6,ANO3,ATP8B3,ATP10B,PLSCR5,ABCA7,ABCA1,ATP11C,PRELID1,ATP9A,KCNN4,TRIAP1,ANO7
GO:0006720	isoprenoid metabolic process	GO_ISOPRENOID_METABOLIC_PROCESS	-0.265983672186016	-1.24072088734313	0.0914714873745276	0.478113753114522	112	RBP4,APOA2,LRP2,AGRN,CYP26B1,RDH10,LRAT,SRD5A3,GPC5,CYP2C9,CYP26A1,SDC1,ALDH3A2,AKR1C3,DGAT2,LPL,STAR,OPN1LW,RDH8,LRP8,RBP1,RDH13,DPAGT1,RARRES2,MVK,APOM,CYP1A2,RETSAT
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS	-0.475786977605159	-1.40165284444857	0.0915957838235612	0.478113753114522	15	PTGIS,TSPO,OPRM1,STAT3,SLC18A2,CD34
GO:0021516	dorsal spinal cord development	GO_DORSAL_SPINAL_CORD_DEVELOPMENT	-0.43287303929609	-1.38327289542869	0.091619163656934	0.478113753114522	20	PAX7,RFX4,LHX5,MDGA1,HOXB8,GSX1,LMO4,UNCX,DRGX,WNT3A,LBX1
GO:0031664	regulation of lipopolysaccharide mediated signaling pathway	GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY	-0.45550872344902	-1.39308425456137	0.0916641432711857	0.478113753114522	17	PRKCA,CD55,LY96,DEFB114,MIF,TRIB1,PRDM1,TRIM5,LTF
GO:0006112	energy reserve metabolic process	GO_ENERGY_RESERVE_METABOLIC_PROCESS	0.315950347085874	1.29436981337759	0.091690594887875	0.478113753114522	66	GNAS,AKT2,PYGB,PYGM,PGM5,CALM3,PHKG1,GYS1,GSK3B,PFKM,GCK,STK40,PPP1R3A,CALM1,PPP1R3B,PHKA2,MTOR,PHKB,GYG1,PPP1CB,PPP1R3E,EPM2A,PRKAG3,PHKG2
GO:0007250	activation of nf kappab inducing kinase activity	GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY	-0.465110071701769	-1.39753872606403	0.0917592051431911	0.478113753114522	16	CHI3L1,TRAF4,CARD14,IRAK1
GO:1903747	regulation of establishment of protein localization to mitochondrion	GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MITOCHONDRION	0.276643972428778	1.24989769865655	0.0921834448845786	0.479581878642182	116	PARL,BAD,FBXW7,GPHA2,DYNLL2,ATPIF1,LRRK2,GZMB,ITGAX,RNF31,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,SIAH3,HUWE1,SIRT4,CYB5R1,PSMB7,KAT2A,NMT1,SAE1,PPP3R1,PPP1R13B,ARIH2,PSMD8,BAG4,USP36
NA	cofactor catabolic process	GO_COFACTOR_CATABOLIC_PROCESS	-0.454929639857312	-1.39131324076481	0.092572565644331	0.479882893226177	17	ALDH1L1,CBR3,CYP4F11,CYP4F2,ALDH1L2,BLVRA,HMOX1,NUDT12,ACOT7,NUDT7,AMBP,ASPDH
GO:0030728	ovulation	GO_OVULATION	-0.454903222821248	-1.39123244943174	0.092615823852576	0.479882893226177	17	LEP,HPGD,IL1R1,AFP,FOXO3,SIRT1,IL4R,MMP19,PLA2G4A,NRIP1,IMMP2L
GO:0090383	phagosome acidification	GO_PHAGOSOME_ACIDIFICATION	-0.413104145262896	-1.37019359285745	0.0926690079016681	0.479882893226177	23	ATP6V1C2,ATP6V1B1,RAB38,ATP6V0D1,ATP6V1H
GO:0060485	mesenchyme development	GO_MESENCHYME_DEVELOPMENT	-0.240247841565565	-1.20264368529366	0.0930139018074864	0.480929022248847	177	SEMA3F,DPPA2,SEMA3C,OSR1,WT1,RDH10,TGFBR1,BMP4,WNT5A,CUL7,SFRP2,BMP2,PTK7,FGFR2,ADAM15,FOXF1,SOX11,RTN4,GBX2,SEMA3A,SEMA3B,ACVR1,CTNNB1,MSX2,HIF1A,SEMA3D,SMAD2,FGF9,GDNF,EDNRB,HGF,CORO1C,SEMA3E,SEMA4B,PKD2,BNC2,SEMA4A,NODAL,MDM2,BASP1,EDN1
GO:0060314	regulation of ryanodine sensitive calcium release channel activity	GO_REGULATION_OF_RYANODINE_SENSITIVE_CALCIUM_RELEASE_CHANNEL_ACTIVITY	0.425458870620376	1.37178519465396	0.0932368392050255	0.481243293891941	23	PRKACA,CALM3,HRC,AKAP6,DMD,PLN,CALM1,TRDN,JPH2,CASQ2,GSTO1,JPH3,CAMK2D,CLIC2,CALM2
GO:0043030	regulation of macrophage activation	GO_REGULATION_OF_MACROPHAGE_ACTIVATION	-0.4125901110608	-1.36848863206657	0.0933933274802458	0.481243293891941	23	MUC5B,WNT5A,SNCA,SLC7A2,NR1H3,THBS1,MIF,IL4R
GO:0000394	rna splicing via endonucleolytic cleavage and ligation	GO_RNA_SPLICING_VIA_ENDONUCLEOLYTIC_CLEAVAGE_AND_LIGATION	0.485310368448997	1.39452355942431	0.0935333370508745	0.481243293891941	15	ZBTB8OS,CLP1,TRPT1,CPSF1,C2orf49
GO:0042451	purine nucleoside biosynthetic process	GO_PURINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS	0.305094712168957	1.27945686510345	0.0937214371089081	0.481243293891941	75	ATP5L,PANK3,CECR1,AK1,ATP5A1,ATP5G2,ATP5D,COASY,AK4,ATP5O,ATP5B,NME6,ADA,ATP5G3,ADSSL1,PANK4,ALDOA,NME5,ACACB
GO:0071825	protein lipid complex subunit organization	GO_PROTEIN_LIPID_COMPLEX_SUBUNIT_ORGANIZATION	-0.367544424915423	-1.337547674939	0.0939453038429148	0.481243293891941	33	PLA2G2A,APOA2,APOC1,LIPC,AGTR1,LPL,ABCA7,ABCA1,PLTP,APOM,ABCG1
GO:0045598	regulation of fat cell differentiation	GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION	-0.276258603789148	-1.25079264623147	0.0941963863399868	0.481243293891941	94	ZBTB7C,TPH1,KLF5,ID4,WNT5A,SFRP2,BMP2,GATA3,CEBPB,LGALS12,XBP1,WNT10B,CEBPA,MSX2,ADIPOQ,LEP,STK3,PPARG,RARRES2,LMO3
GO:0051961	negative regulation of nervous system development	GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT	-0.224747055376415	-1.17481928810073	0.0942797711908476	0.481243293891941	244	SEMA3F,SEMA3C,SOX3,TBX6,DLX1,NKX6-1,TRAF3IP1,NLGN1,EFEMP1,ID4,BMP4,WNT5A,ULK2,TRIM11,TNFRSF21,SPOCK1,RFX4,CEND1,LPAR1,SOX11,KATNA1,TSPO,RTN4,CALR,SEMA3A,SEMA3B,CTNNB1,STAT3,TP73,ISL2,YWHAH,F2,ROBO2,EIF2AK3,MAG,SEMA3D,CERS2,CDK5,DPYSL3,KCTD11,SORL1,FGF13,EIF2AK4,LMX1A,EDNRB,SEZ6,PCM1,SEMA3E,ADCYAP1,SEMA4B,ARHGEF15,TULP3,LRP1,RHOA,SEMA4A,FSTL4,SRGAP2
GO:0055123	digestive system development	GO_DIGESTIVE_SYSTEM_DEVELOPMENT	-0.252347614828263	-1.21914839244075	0.0945707565660525	0.481243293891941	139	ASS1,KLF5,NKX3-2,BMP4,WNT5A,SFRP2,GATA3,FGFR2,BBS7,FOXF1,SOX11,COBL,XBP1,CTNNB1,CDKN1A,WDR19,EGFR,GATA5,HIF1A,CPS1,SPDEF,TYMS,CCNB1,SMAD2,ZIC3,RARRES2,FGF9,NKX2-3,EDNRB,CLDN18,STX2
GO:0071774	response to fibroblast growth factor	GO_RESPONSE_TO_FIBROBLAST_GROWTH_FACTOR	-0.265141349181117	-1.23679174486052	0.0946248465445442	0.481243293891941	112	ESRP2,POLR2H,FLRT3,FGF22,KLB,CTGF,FGF7,FGFR2,ITGB1BP1,SNCA,FLRT2,FGF17,CTNNB1,FGF18,FLRT1,POLR2K,STAR,CPS1,FGFBP1,FGF4,UBA52
GO:0046636	negative regulation of alpha beta t cell activation	GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	0.424608707193266	1.36904405636097	0.0946328202490724	0.481243293891941	23	HLX,XCL1,CD300A,SHH,IL4,HMGB1,LILRB1,BCL6,TNFRSF14,TNFSF4,JAK3,FOXP3,RC3H1
GO:0060261	positive regulation of transcription initiation from rna polymerase ii promoter	GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER	0.466586077953344	1.38609270490054	0.0946473739026931	0.481243293891941	17	PSMC6,TAF1,PSMC5,CREB1,NKX2-5,GTF2F2,SRF,PAXIP1,IRF8
GO:0034121	regulation of toll like receptor signaling pathway	GO_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	-0.341389904515534	-1.31540722181168	0.0951751042554146	0.481869799242452	42	SMPDL3B,TYRO3,LY96,SARM1,NLRP6,IRF7,IRF4,IRAK3,NR1H3,TLR9,PDPK1,TLR2
GO:0035966	response to topologically incorrect protein	GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN	-0.248858342261063	-1.21266932629219	0.0954162768942937	0.481869799242452	147	KDELR3,HSPA6,SEC63,CUL7,SERPINH1,PDIA6,CREB3L1,CHAC1,CALR,SEC61G,SERP2,ATF3,DDX11,SSR1,XBP1,ATP6V0D1,TOR1A,IGFBP1,TBL2,SERP1,ERP44,EIF2AK3,ATF6,PDIA5,MBTPS2,RNF126,JKAMP,THBS1,BAX,CREB3L3,DNAJC3,HDGF,HSP90AA1,DNAJB9,UBXN4,BHLHA15,SEC61A1,SEC31A,NFE2L2,AMFR,UBE2J2,THBS4,ZBTB17,HSPA4L,DERL2,ASNA1
GO:0048024	regulation of mrna splicing via spliceosome	GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME	0.32603280899382	1.30043401122151	0.0954525229153689	0.481869799242452	58	C1QBP,SNRNP70,ACIN1,RBM10,SF3B4,SRSF4,TIA1,SFSWAP,THRAP3,HNRNPA2B1,RNPS1,PRPF19,RBFOX1,JMJD6,RBM5,RBM8A,RBM42
GO:0043487	regulation of rna stability	GO_REGULATION_OF_RNA_STABILITY	0.269699471368651	1.23969127252327	0.0954542375177833	0.481869799242452	129	CPEB3,METTL3,PCID2,MAPKAPK2,DCP2,SCGB1A1,VIP,PSMD11,PSMD2,PSMC6,QKI,EXOSC4,EXOSC7,PSMC5,PSMB7,PSME4,CNOT6L,THRAP3,MTOR,YTHDF2,PSMA8,EXOSC3,PSMD8,PSMB10,HSPB1,DCP1A,ANP32A,PSMD3,PSMB1,YBX1,PSMA5,PSMB9,APOBEC1,EIF4G1,PSMD6,SERBP1,PSMB3,PSMB6,NUP214,PSMD1
GO:0050865	regulation of cell activation	GO_REGULATION_OF_CELL_ACTIVATION	-0.203688541085463	-1.13572975675453	0.0956227798785379	0.481869799242452	444	PRKCA,CD55,TCF3,TYRO3,DPP4,CNR1,TNFSF11,CCL19,EFNB3,RARA,IL18,CYP26B1,MUC5B,BMP4,WNT5A,TNFRSF21,PTPN2,CTGF,TNFSF14,GATA3,CEBPB,HLA-DRB5,FOXF1,MZB1,C1QTNF1,SOX11,IL27,SNCA,ANXA1,TACR1,CLCF1,MAP3K8,XBP1,PLA2G2D,CTNNB1,BST1,CNR2,IL6ST,PYCARD,CCL21,NR4A3,RIPK2,SLC7A2,CDKN1A,SLC39A10,IL36B,F2,IRF4,RIPK3,ADAMTS18,IGHG4,CASP3,LEP,TNFSF9,CHRNB2,LILRB2,IGHG2,VAMP8,IGHG1,WHSC1,RAG1,ZBTB1,PAK3,NR1H3,ATP11C,LAT,FAS,PGLYRP1,PRELID1,IGHD,NLRP3,IL5,SART1,RPS6KA1,BTLA,SOX15,THBS1,GRAP2,IGKC,PDPK1,GAL,NKAP,TXK,AHR,APLF,ABAT,IL2RA,IGLL1,MIF,LMO4,LMO1,IGLC1,VTCN1,CDC42,FCER1A,HLA-DRB1,GPAM
GO:0045682	regulation of epidermis development	GO_REGULATION_OF_EPIDERMIS_DEVELOPMENT	-0.310570023964382	-1.28774947768215	0.0956295382929168	0.481869799242452	59	NAB2,SFN,BMP4,AQP3,HOXA7,GRHL2,WNT10B,ERRFI1,HPSE,TMEM79,MSX2,TRADD,IL20,CDH3,KEAP1
GO:0030201	heparan sulfate proteoglycan metabolic process	GO_HEPARAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS	-0.390003077740961	-1.35022673823774	0.0962135729861891	0.482994957092168	27	SULF1,LIPC,B3GALT6,HS6ST3,EXTL2,SULF2,HPSE,NDST3,EXT1,HS3ST5
GO:0006367	transcription initiation from rna polymerase ii promoter	GO_TRANSCRIPTION_INITIATION_FROM_RNA_POLYMERASE_II_PROMOTER	0.263098681117347	1.22911060746898	0.0962144844448192	0.482994957092168	145	NR1I2,NR3C2,PPARD,ESRRA,NOTCH3,NR2F6,PPARA,ESR1,CREBBP,DACH2,TCF4,YAP1,TAF1,MED7,MED27,TEAD2,MED24,DACH1,MED25,MED12,RXRB,GTF2H3,AR,RXRG,MED17,POLR2I,ESR2,THRAP3,TBX5,MAZ,RXRA,ESRRG,GTF2H5
GO:0016048	detection of temperature stimulus	GO_DETECTION_OF_TEMPERATURE_STIMULUS	-0.462046476023295	-1.38833339196751	0.096283308439942	0.482994957092168	16	TRPM3,LXN,MMP24,ANO3,PAWR,HTR2A,DRGX,CALCA,ADORA1,EPHB1,NTRK1
GO:0051153	regulation of striated muscle cell differentiation	GO_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION	0.298077944764879	1.2697118916822	0.0967211681384979	0.484469422550869	82	EHD1,HDAC9,CFLAR,ANKRD2,PRICKLE1,DMPK,PIN1,BMP10,NACA,HDAC4,AKAP6,CAV3,DDX39B,AKAP13,SMYD1,EZH2,SHH,EP300,MTOR,IL4,NKX2-5,SCGB3A1,TRIM32,MYLK3,CXCL9,GDF15,PROX1,MSX1,FLOT1,HDAC5,MEF2C
GO:0045103	intermediate filament based process	GO_INTERMEDIATE_FILAMENT_BASED_PROCESS	-0.342889139740009	-1.31340336968565	0.0971282648626854	0.485785645657948	41	KRT71,KRT74,AGFG1,KRT18,TCHH,KRT25,TOR1A,NEFM,KRT14,MTM1,KRT16
GO:0048710	regulation of astrocyte differentiation	GO_REGULATION_OF_ASTROCYTE_DIFFERENTIATION	-0.398674075820246	-1.35235221402144	0.0974050229614818	0.486447043454522	25	ID4,BMP2,CLCF1,IL6ST,F2,MAG
GO:0046164	alcohol catabolic process	GO_ALCOHOL_CATABOLIC_PROCESS	-0.315035203691998	-1.28721667473494	0.0980619626040671	0.488003045725572	55	SMPDL3B,CHDH,SMPD3,MTMR7,ALDH3B1,HAO1,LIPC,SRD5A3,SMPDL3A,GK,AKR1C3
GO:0090263	positive regulation of canonical wnt signaling pathway	GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY	0.276423069656069	1.24373736991597	0.0981344368256357	0.488003045725572	113	TRPM4,BIRC8,LRP6,DVL2,PSMD11,DIXDC1,PPP2R3A,LRRK2,PIN1,PSMD2,PSMC6,RNF220,YAP1,PSMC5,PSMB7,PSME4,UBR5,GPRC5B,DAPK3,PSMA8,PSMD8,PSMB10,PSMD3,PSMB1,NFKB1,SMAD3,LGR5,LRRK1,PSMA5,PSMB9,BAMBI,EDA,PSMD6,JUP,USP34,PSMB3,PSMB6,CTDNEP1,PSMD1
GO:0007254	jnk cascade	GO_JNK_CASCADE	-0.288183592278524	-1.25921798780323	0.0982120021390872	0.488003045725572	77	MAPK8IP1,TNFSF11,CCL19,MAPK10,IRAK4,WNT5A,MAP2K4,MDFIC,IRAK1,NPHS1,RIPK2,RIPK1,UBA52,IKBKG,MAP3K11,NOD1,FCER1A,MAP3K2,PTGER4,UBB,TRIB1,AXIN1,MAP3K12,TAB2
GO:0010662	regulation of striated muscle cell apoptotic process	GO_REGULATION_OF_STRIATED_MUSCLE_CELL_APOPTOTIC_PROCESS	0.43534699613717	1.37020471561083	0.0982965136666482	0.488003045725572	21	CAMK2A,HAND2,NACA,HMGCR,BAG3,JAK2,SIRT4,SIRT5,NKX2-5,HEY2
GO:0009617	response to bacterium	GO_RESPONSE_TO_BACTERIUM	-0.201688754894099	-1.12989917394262	0.0987697206542191	0.488560678987961	468	TNFRSF8,PLA2G2A,ASS1,SLPI,DEFA5,CNR1,CCL3,BDKRB1,PRB3,ANXA3,DEFB123,RARA,IL18,MUC5B,WNT5A,HP,TNFRSF21,ALPL,DEFB124,TNFRSF11B,ENTPD2,MGST1,LY96,CEBPB,TG,HLA-DRB5,IL27,TSPO,SNCA,OPRM1,DEFA6,SOCS1,DEFB133,IRAK1,XBP1,CXCL1,HIST1H2BE,HIST1H2BK,S100A12,NLRP6,DEFB132,CNR2,GNG12,PYCARD,RIPK2,CHUK,KLK3,STAR,HIF1A,CPS1,BAIAP2,SEMG2,PPM1D,TNFRSF1A,IGHG4,IRAK3,CASP3,LILRB2,IGHG2,IGHG1,C5AR1,S100A9,IFNE,SPARC,ABCA1,PTGER2,TNFRSF25,NR1H3,EDNRB,IL24,DEFB121,PROS1,MBL2,FAS,PGLYRP1,CLEC4E,IGHD,NLRP3,TLR9,CYP1A2,DCN,IFNAR1,NOD1,ATP4B,IGKC,ADAM9,HMGB2,F2R,DEFB114,DROSHA,TLR2,IGLL1,TMF1,EDN1,JUNB,IGLC1,CEBPE,HLA-DRB1,HIST1H2BF,ELANE,PTGER4,TRIB1,LALBA,F3,CXCL5,ABL1,SOCS3,PAWR,CARD9,STAB2,HNRNPA0,PF4,TIMP4,IL10,PLA2G4A,FAU,LYZ,GALP,THBD,PTGFR,WFDC12
GO:0051043	regulation of membrane protein ectodomain proteolysis	GO_REGULATION_OF_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS	-0.434675246936066	-1.36903317924174	0.0989400060819323	0.488560678987961	19	TIMP1,PTPN3,TIMP2,ADAM9,SNX33,TIMP4,IL10,FURIN,APOE
GO:0000075	cell cycle checkpoint	GO_CELL_CYCLE_CHECKPOINT	0.252086575443585	1.21155863691215	0.0989655115155339	0.488560678987961	177	BRSK1,RPA4,PPP2R5C,FBXO6,FOXN3,TAOK2,NSUN2,MAPKAPK2,NPM1,CSNK2A1,ZAK,CCND1,TAOK3,MAD2L1,PLAGL1,FZR1,CDK5RAP3,TFDP2,CNOT6L,SMC1A,CNOT4,PRCC,DGKZ,EP300,FBXO31,CCNE2,INTS3,CDKN1B,CDK1,ATF2,APC,USP28,PRPF19,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,CLSPN,GIGYF2,KLHL22,FOXO4,TPR,ZWILCH,PRKDC,MAD1L1,MRE11A,CHFR,CNOT1,MAD2L1BP,TIPIN
GO:0032526	response to retinoic acid	GO_RESPONSE_TO_RETINOIC_ACID	-0.2707744379702	-1.23949316623405	0.0989894186184758	0.488560678987961	100	WNT6,RBP4,OSR1,RARA,CYP26B1,SNW1,AQP1,BMP4,WNT5A,SLC10A3,AQP3,T,WNT9A,PTK7,KLF4,WNT10B,WNT7B,LEP,PPARG,ABCA1,LTK
GO:0000959	mitochondrial rna metabolic process	GO_MITOCHONDRIAL_RNA_METABOLIC_PROCESS	0.428363085702988	1.36443254332853	0.0994826094161404	0.490275934545722	22	TARS2,ELAC2,KIAA0391,EARS2,MRPL12,POLRMT,TFB2M,PUS1,AARS2,PNPT1,TRMT61B,SLC25A33,SUPV3L1,PPARGC1B
GO:1904062	regulation of cation transmembrane transport	GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT	0.24857944010173	1.20551578125836	0.099770282106794	0.490974809315013	190	AGT,PRKACA,OPRL1,ANK2,DRD4,SCN5A,CALM3,CACNA2D1,RYR2,S100A1,NEDD4L,CAPN3,XCL1,ATP1A2,DRD2,HRC,OPRK1,RNF207,KCNJ2,VAMP2,PPIF,PCSK9,WNK2,CXCL11,FXYD3,ARF1,AKAP6,CAV3,DMD,CXCR3,FXYD1,PLN,SLC8A1,KCNH2,CALM1,AHNAK,GLRX,CACNA1C,TSPAN13,HAMP,KCNRG,HOMER1,CYBA,ANK3,KCNIP2,CXCL9,PLCG1,SLC30A1,HTT,FGF12,TRDN,SUMO1,JPH2,PRKCE,SNTA1,COMMD1
GO:0098781	ncrna transcription	GO_NCRNA_TRANSCRIPTION	0.301520182033108	1.2704122829691	0.100187742354324	0.491227902743141	77	ELL3,NPM3,BRF1,GTF3C5,NCBP1,GTF3C1,SNAPC3,ELL,INTS2,ZC3H8,TAF1B,POLR2I,INTS3,RPRD1A,NCBP2,SRRT,POU2F1,TAF6,GTF2F2,POLR2C,RPRD1B,SNAPC4,PHAX,GTF3A,TAF11,POLR2G,CCNT1,POLR2L,INTS5
GO:0045723	positive regulation of fatty acid biosynthetic process	GO_POSITIVE_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS	-0.469518038450303	-1.38318475513199	0.10025323030972	0.491227902743141	15	SLC45A3,ANXA1,NR1H3,HNF4A,PLA2G4A
GO:0010921	regulation of phosphatase activity	GO_REGULATION_OF_PHOSPHATASE_ACTIVITY	0.274250494159043	1.23908378879666	0.100259527386969	0.491227902743141	116	CEP192,PPP2R5C,PPP1R17,PPP2R3A,ROCK2,CALM3,ELL,TSC1,WNK1,DRD2,PCDH11X,SYTL2,DLG2,AKAP6,JAK2,CDK5RAP3,CD300A,PPME1,AGTR2,CALM1,PPP1R37,IKBKB,TNF,SPOCD1,PPP1R12A,BAG4,PPP6R1,CD2BP2,HTT,SMAD3,UBN1,CCDC8,SFI1,PCIF1,MEF2C,FKBP15,ZCCHC9,MPHOSPH10,GPLD1,PPP1R11,PPP1R26,PPP2R2B,NUAK1,PPP1R15A,PPP2R5B,PPP2R1A,PPP2R5E,EIF2AK2,CRY2
GO:0031023	microtubule organizing center organization	GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION	0.30141026404215	1.26994915919115	0.100521116628358	0.491415692555748	77	BRSK1,CEP192,NDE1,TUBGCP5,WDR62,NPM1,CLASP1,TUBE1,PAFAH1B1,ROCK2,C2CD3,TUBGCP2,GOLGA2,PLK4,CEP68,CDK1,PPP1R12A,GADD45A,TUBGCP6,HAUS8,BCAS3,TUBGCP3,CKAP5,UVRAG
GO:0070848	response to growth factor	GO_RESPONSE_TO_GROWTH_FACTOR	-0.2025011547931	-1.13070650312308	0.100589843188031	0.491415692555748	452	CGN,GDF5,HAP1,DTYMK,ESRP2,AMHR2,ANXA3,KDR,ZCCHC12,SPINT1,POLR2H,FLRT3,FGF22,TGFBR1,PRKD1,BMP4,WNT5A,BMP2,FMOD,KLB,CTGF,T,GAS1,FGF7,GATA3,FGFR2,ITGB1BP1,SKIL,SNCA,OPRM1,FLRT2,GDF10,FGF17,ACVR1,KLF4,XBP1,FUT8,HAS1,MEN1,HTR3A,CTNNB1,FGF18,BMPR1B,CAT,ERRFI1,DDC,RIPK1,PAX9,FLRT1,EGFR,GATA5,POLR2K,STAR,TNMD,MSX2,CPS1,LRP8,FGFBP1,LEFTY1,FGF4,UBA52,MSTN,BMP5,SOX6,CASP3,EEF1A1,SMAD2,MT1G,HPGD,SPARC,SMURF2,LTBP2,FGF9,RAPGEF3,CCNA2,MAGI2,FAS,GTF2F1,OPRD1,HGF,INPP5K,IL1R1,ETV2,TGIF1,EPHA2,WWOX,ADAM9,PDPK1,ACVR2B,F11R,FLT3,RHOA,NODAL,MDM2,FSHB,MYC,CPNE3,EDN1,PDGFD,FGFR4
GO:0007281	germ cell development	GO_GERM_CELL_DEVELOPMENT	-0.233552232094992	-1.18570966621407	0.101047676890374	0.491870896215735	195	CFTR,TDRD1,TARBP2,RARA,WT1,SPANXB1,AGFG1,BMP4,PYGO1,DMRT1,GALNTL5,IQCF1,SPAG6,ACVR1,INSL3,REC8,PTCHD3,CTNNB1,BMPR1B,FAM9A,YBX2,RFX2,PAQR5,MOV10L1,PRDM14,CCNB1,TSSK6,KIAA0196,FBXO5,TAF4B,FMN2,DDX25,TTC26,BAX,DND1,HMGB2,RNF8,NPM2,AURKC,TMF1,GPR149,PYGO2,FOXO3,PABPC1L,RPS6,CEP57,FOXL2,CHD5,BCL2,ADAD1,OSBP2,RPS6KA2,PRDM1,FNDC3A,CAPZA3,KLHL10,RAN,CCDC63,SPACA1
GO:0006700	c21 steroid hormone biosynthetic process	GO_C21_STEROID_HORMONE_BIOSYNTHETIC_PROCESS	-0.468662941930896	-1.38066566880739	0.10133541112049	0.491870896215735	15	CYP11A1,FDX1L,FDXR,STAR,STARD5,FSHB
GO:0060216	definitive hemopoiesis	GO_DEFINITIVE_HEMOPOIESIS	0.480000329943317	1.3792653364828	0.101488875257904	0.491870896215735	15	ADAR,TEK,HOXB3,GATA2,LYL1,TGFBR3,HIPK1,ZFP36L2,TAL1,HOXB4,MEIS1,MFAP5
GO:0043252	sodium independent organic anion transport	GO_SODIUM_INDEPENDENT_ORGANIC_ANION_TRANSPORT	-0.407888065765299	-1.3528927770961	0.101492537313433	0.491870896215735	23	SLC22A24,SLC22A25,SLC22A20,SLCO5A1,SLC22A8,SLCO1B3,SLCO2A1
GO:0006896	golgi to vacuole transport	GO_GOLGI_TO_VACUOLE_TRANSPORT	0.420600166279822	1.35611952368121	0.101759670842364	0.491870896215735	23	VPS13A,KIF16B,VTI1A,TGOLN2,SORT1,GBF1,AP1G1,EPS15,RAB14,VPS13C,KLHL20
GO:0002028	regulation of sodium ion transport	GO_REGULATION_OF_SODIUM_ION_TRANSPORT	0.307683954298226	1.274102339116	0.101865566370433	0.491870896215735	70	AGT,DRD4,ADRB2,DMPK,SCN5A,NEDD4L,ATP1A2,DRD2,PCSK9,WNK2,FXYD3,ARF1,CAV3,DMD,PKP2,FXYD1,SLC8A1,GLRX,NKX2-5,CNTN1,P2RX7,ANK3,FGF12,CNKSR3,PRKCE,SNTA1,COMMD1,ATP1B2,UTRN
GO:0006636	unsaturated fatty acid biosynthetic process	GO_UNSATURATED_FATTY_ACID_BIOSYNTHETIC_PROCESS	-0.318581824368205	-1.28616818753317	0.10193218112216	0.491870896215735	52	PTGIS,ALOX15,ALOX12B,TBXAS1,AKR1C3,DECR2,PLA2G4F,GGT1,PTGS1,MIF,DEGS1,EDN1,FCER1A
GO:0045494	photoreceptor cell maintenance	GO_PHOTORECEPTOR_CELL_MAINTENANCE	0.380628955140423	1.33256319120632	0.101946786618346	0.491870896215735	32	RHO,BBS12,CDHR1,PROM1,ABCA4,RP1,NXNL1,CLN8,TUB,PCDH15,USH2A,MKKS
GO:0021515	cell differentiation in spinal cord	GO_CELL_DIFFERENTIATION_IN_SPINAL_CORD	-0.317046780399626	-1.28518262908525	0.101998183469573	0.491870896215735	53	PAX7,LHX4,NKX6-1,GBX1,GDPD5,HOXC10,OLIG3,LHX5,MDGA2,EVX1,ISL2,MDGA1
GO:0048667	cell morphogenesis involved in neuron differentiation	GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION	-0.210742714344319	-1.14568488514296	0.102455081607461	0.493367388684856	345	SEMA3F,NTNG1,LHX9,SEMA3C,LHX4,LRRN1,EZR,SLITRK2,PARD6B,KIF5A,EFNB3,GBX1,PDZD7,FLRT3,WNT5A,ULK2,FMOD,SLITRK4,GAP43,KRAS,GATA3,UNC5D,FGFR2,NEO1,EFNA5,S100A6,GBX2,SEMA3A,LRFN4,SEMA3B,FLRT2,UNC5A,OTX2,PLXNB2,SPTBN4,EVL,COBL,ATP2B2,BMPR1B,LRRC38,PLXNA2,BRSK2,SLIT3,FEZF1,ISL2,NR4A3,ROBO2,BAIAP2,ARTN,EPYC,RAB10,CDH11,FZD3,USP33,CHRNB2,CDK5,CDH4,EXT1,PAK3,LMX1A,BOC,LINGO3,TLR9,CTNND2,STXBP1,DOCK7,SPTBN2,ATL1,NRCAM,LRFN3,NTN4,SEMA4A,SLITRK5,PLXNA4,LLGL1,ECM2,POU4F2,SPTAN1,ISPD
GO:0072378	blood coagulation fibrin clot formation	GO_BLOOD_COAGULATION_FIBRIN_CLOT_FORMATION	0.414440924096902	1.35046734337612	0.10291144359078	0.494634637760515	24	KLKB1,VWF,C1QBP,F8
GO:0090279	regulation of calcium ion import	GO_REGULATION_OF_CALCIUM_ION_IMPORT	0.286195704983908	1.25120783821445	0.103113312093088	0.494634637760515	95	PRKACA,PDGFB,ANK2,TRPV2,CALM3,RYR2,CAPN3,XCL1,ATP1A2,LGALS3,HRC,CXCL11,AKAP6,CAV3,DMD,CXCR3,UCN,PLN,SLC8A1,CALM1,CACNA1C,SEMG1,HOMER1,CYBA,CXCL9,PLCG1,ZP3,SLC30A1,HTT,TRDN,JPH2,PRKCE,EGF,DHRS7C
GO:0046486	glycerolipid metabolic process	GO_GLYCEROLIPID_METABOLIC_PROCESS	0.22468639648934	1.16612526302935	0.103222145154171	0.494634637760515	339	PIK3C2B,CHAT,PIK3R1,MTMR1,LPIN1,DDHD2,MOGAT1,PDGFB,PCYT1A,AGK,SLC27A5,ACP6,CYP2E1,TAZ,PAFAH1B1,DBI,CHPT1,APOC3,PLD1,PLA2G4C,FABP9,DRD2,LCAT,PCSK9,PLA2G5,CEL,SERINC5,SMG1,INPP5J,ABHD2,PIP5K1B,ARF1,INPPL1,FABP7,PLCE1,LPCAT4,IMPA2,AGPAT3,MTMR4,FGF1,PIK3R3,PI4KB,CAV3,PTEN,INPP5D,ABHD6,PIK3C3,INPP1,PIP4K2C,DGAT2L6,IRS1,IP6K3,PLA2G15,MGLL,PIKFYVE,SMPD4,PI4K2A,GPAA1,PIP4K2B,IP6K2,FGFR1,AGPAT1,CDS2,ERBB4,MBOAT2,INSIG1,PCYT1B,LIPF,PIK3R5,PIK3C2G,MPPE1,HADHB,PLA2G4E,PLD6,EFR3B,FABP3,PIGM,CETP,LCLAT1,FAM126A,CD80,PIP5K1C,GAB1,FGF6,TTC7B,VAC14,HADHA,FGF8,INPP5A,GPCPD1,MTMR14,PNPLA6,EGF,SLC27A1,SACM1L,INPP5F,CHKA,TAMM41,MBOAT1,DPM2,PLA2G4D,PIGS,TMEM150A,APOA5,MTMR2,PCYT2,EFR3A,PIK3R6,CDIPT,PIK3R2,PIK3CB,FABP12,PLA1A,EREG
GO:0009200	deoxyribonucleoside triphosphate metabolic process	GO_DEOXYRIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS	-0.457165527337617	-1.37366736939955	0.10336169015304	0.494634637760515	16	DTYMK,DUT,GUK1,RRM2B,TYMS
GO:0034249	negative regulation of cellular amide metabolic process	GO_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS	0.276761603644621	1.24034346981964	0.103452996132918	0.494634637760515	110	CPEB3,ADAR,METTL3,DDX3X,EIF2B5,WTIP,PAIP2B,TNRC6C,ZCCHC11,SAMD4A,TSC1,CPEB2,SMAD1,QKI,TNRC6A,CELF1,CNOT6L,LIN28B,UNK,TIA1,PAIP2,EIF4E2,DAPK3,SRRT,HNRNPA2B1,LIMD1,MOV10,DICER1,CNOT8,EIF2B4,SMAD3,GIGYF2,TPR
NA	synapsis	GO_SYNAPSIS	0.394846609626319	1.33791032698827	0.103849318826003	0.495825258394791	28	SUN1,DMC1,SYCP2,TEX11,RAD21L1,SPO11,MLH3,BAG6,MRE11A,UBE2B,CCDC155
GO:0031348	negative regulation of defense response	GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE	-0.255882190896729	-1.21467738594869	0.104299556897307	0.497269558805009	125	SMPDL3B,PTGIS,TYRO3,TARBP2,TRAF3IP1,PTPN2,HTRA1,GATA3,FOXF1,SERPING1,RPS19,KLF4,NLRP6,CNR2,SAA1,TNFRSF1A,ADIPOQ,IRAK3,MMP26,TRIM38,NOV,PPARG,NR1H3,PGLYRP1,HGF,MVK,NLRP3,NLRP12,ADCYAP1,IL2RA,ELANE,PTGER4,IFI16,SOCS3,IL20RB,CD276,CUEDC2,SERPINF1,SERPINC1,IL10
GO:0032231	regulation of actin filament bundle assembly	GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	0.304436268336775	1.26721424320793	0.104863837203162	0.499252724223256	72	AMOT,SHANK3,PIK3R1,SERPINF2,CLASP1,DLC1,ROCK2,TSC1,SHANK1,EPHA1,ARAP1,PPP1R9A,LIMK1,MTOR,S1PR1,PPFIA1,BAG4,WNT11,RDX,MKKS,SMAD3,PFN2,TMEFF2,PRKCQ,NOX4,SYNPO,TACSTD2
GO:0050849	negative regulation of calcium mediated signaling	GO_NEGATIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING	0.468586173845374	1.3691783532759	0.105287612675402	0.499717930243588	16	ITPR1,CALM3,CALM1,SLA2,TRDN,CASQ2,PRNP,GSTO1,CLIC2,CALM2
GO:0032204	regulation of telomere maintenance	GO_REGULATION_OF_TELOMERE_MAINTENANCE	0.31758379964619	1.27981419187214	0.105329386952129	0.499717930243588	61	HMBOX1,SMG6,MCRS1,OBFC1,MAP3K4,ERCC1,MAPKAPK5,TCP1,ERCC4,ACD,TERF2IP,MAPK1,CCT3,ATRX,MRE11A,CCT7,WRAP53,CCT4,PRKCQ,PKIB,MAP2K7,HNRNPU,NEK7,ATM,MAPK3,CCT8,ATR,NAT10,DHX36,TNKS,HNRNPC,DKC1,SLX4
GO:0043094	cellular metabolic compound salvage	GO_CELLULAR_METABOLIC_COMPOUND_SALVAGE	0.378995183532636	1.32684343741993	0.105406931215968	0.499717930243588	32	TK1,CECR1,UPP2,GMPR,UCKL1
GO:0097191	extrinsic apoptotic signaling pathway	GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.288493422985382	1.24953496081476	0.105958769690338	0.500757926313606	90	DDX3X,BAD,PIK3R1,KIAA0141,MOAP1,CD70,TNFRSF10D,BAG3,GSK3B,JAK2,CASP10,RAF1,DDX47,TNFRSF10B,CASP8AP2,G0S2,IL4,TNF,P2RX7,DEDD,SGPP1,SORT1,IL2,SMAD3,FASLG,BID,TNFRSF18,NDUFA13
GO:0072215	regulation of metanephros development	GO_REGULATION_OF_METANEPHROS_DEVELOPMENT	-0.405231185385013	-1.34408037345454	0.106035996488148	0.500757926313606	23	PAX8,WT1,BMP4,CTNNB1,ADIPOQ,GDNF,WNT9B,BASP1,MYC,RET
GO:0048844	artery morphogenesis	GO_ARTERY_MORPHOGENESIS	0.336379012274664	1.29558507929101	0.106175280898876	0.500757926313606	49	NRP1,TBX2,NOTCH3,HAND2,EYA1,CHD7,NPRL3,SIX1,DLL4,MYLK,GJA5,ZMIZ1,VEGFA,ENG,WNT11,HEY2,SMAD7,FGF8,PROX1,SRF,SEC24B,FOXC2,MYOCD
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	GO_NEGATIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	-0.349355123537322	-1.30666074955311	0.106221378308947	0.500757926313606	37	RARA,CIDEA,TSPO,ERRFI1,ADIPOQ,IRAK3,ORM1,POMC,CD34,PTGER4,IL10,TRIM27,LTF,GAS6
GO:1900271	regulation of long term synaptic potentiation	GO_REGULATION_OF_LONG_TERM_SYNAPTIC_POTENTIATION	0.444383695358854	1.35986623764671	0.106552516492476	0.500946686965701	19	SHANK3,NLGN3,DRD2,PPP1R9A,PAIP2,CREB1
GO:1903311	regulation of mrna metabolic process	GO_REGULATION_OF_MRNA_METABOLIC_PROCESS	0.278841177487602	1.23946608350849	0.106559069479335	0.500946686965701	105	CPEB3,RNF40,C1QBP,PAF1,SNRNP70,NCBP1,ACIN1,TNRC6C,RBM10,SF3B4,SRSF4,TIA1,SFSWAP,TNRC6B,THRAP3,NCBP2,HNRNPA2B1,RNPS1,PRPF19,CNOT8,RBFOX1,JMJD6,APOBEC1,RBM5,RBM8A,CNOT1,RBM42,PTCD2,RNF20,DYRK1A,DHX34,POLR2G,ZFP36L2,CCNT1,SAFB,RC3H1,SRSF12,DAZAP1,UPF1,PNPT1,NANOS3,MBNL2
GO:0008543	fibroblast growth factor receptor signaling pathway	GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	-0.280894384497272	-1.24168505160237	0.106709951654717	0.500956342077791	82	ESRP2,POLR2H,FLRT3,FGF22,KLB,CTGF,FGF7,FGFR2,FLRT2,FGF17,FGF18,FLRT1,POLR2K,FGFBP1,FGF4,UBA52
GO:0032206	positive regulation of telomere maintenance	GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE	0.349730044744404	1.30273682555923	0.10687725631769	0.501042959283208	42	HMBOX1,OBFC1,MAP3K4,ERCC1,MAPKAPK5,TCP1,ACD,MAPK1,CCT3,ATRX,MRE11A,CCT7,WRAP53,CCT4,PRKCQ,PKIB,MAP2K7,NEK7,ATM,MAPK3,CCT8,ATR,DHX36,TNKS,DKC1,SLX4
GO:0070988	demethylation	GO_DEMETHYLATION	0.334028458909179	1.29207680301796	0.107392912283221	0.502160814750172	50	TET1,PHF2,KDM3B,CYP2D6,KDM2B,CYP51A1,KDM5A,PPME1,TET2,AICDA,HSF4,ALKBH5,CYP3A4,FTO,JMJD6,APOBEC1,KDM5C,UBE2B,CYP1A1
GO:0044818	mitotic g2 m transition checkpoint	GO_MITOTIC_G2_M_TRANSITION_CHECKPOINT	0.450982833641449	1.36061143452353	0.107414078021427	0.502160814750172	18	FOXN3,TAOK3,CDK5RAP3,CDK1,HUS1,CLSPN,FOXO4,MRE11A
GO:0006465	signal peptide processing	GO_SIGNAL_PEPTIDE_PROCESSING	-0.410005297321805	-1.34418234966126	0.108073800091922	0.504544259513743	22	SEC11C,F7,F2,SPCS1,PROS1,HM13,FURIN,GAS6,IMMP2L,SEC11A,CLN5
GO:0048469	cell maturation	GO_CELL_MATURATION	-0.255673344694353	-1.21157918438666	0.108619226572918	0.505969836050946	123	CFTR,CCL19,NKX6-1,IRX5,EPB42,AGRN,GATA3,FOXA1,IQCF1,SPTBN4,XBP1,INSL3,REC8,CTNNB1,CCL21,CEBPA,CDKN1A,TMEM79,HIF1A,L3MBTL3,TYMS,CCNB1,KIAA0196,PPARG,CBFB,FBXO5,PICK1,NRCAM,POU2F2,NTN4,BHLHA15,FOXO3,FAM20C,PABPC1L,RET,HOXB13
GO:0090287	regulation of cellular response to growth factor stimulus	GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	-0.226769591524126	-1.16955062413572	0.108716364104545	0.505969836050946	220	VTN,VASN,GDF5,CDKN2B,ADAMTS3,ITGA3,SULF1,SNW1,TGFBR1,BMP4,WNT5A,SFRP2,NPNT,HTRA1,GATA3,FGFR2,NEO1,SNX25,CYR61,SOX11,SKIL,CRB2,CIDEA,OTX2,MEN1,CTNNB1,FGF18,SULF2,TOB1,MSX2,HIF1A,FGFBP1,PRDM14,FGF4,UBA52,MYOF,DAB2,SMAD2,SMURF2,FGF9,IL17F,ONECUT1,DCN,CTDSPL2,THBS1,PDPK1,ZNF703
GO:1901659	glycosyl compound biosynthetic process	GO_GLYCOSYL_COMPOUND_BIOSYNTHETIC_PROCESS	0.282316976889662	1.24024603435918	0.108852481705102	0.505969836050946	98	TK1,ATP5L,PANK3,CECR1,UPP2,AK1,UCKL1,ATP5A1,ATP5G2,ATP5D,COASY,TYW5,AK4,ATP5O,ATP5B,NME6,ADA,ATP5G3,ADSSL1,PANK4,ALDOA,NME5,ACACB,CAD,DHODH,IMPDH1,CHCHD10,UMPS,PDC,ATP5F1,LCMT2,ATP5H,TCIRG1
GO:0061351	neural precursor cell proliferation	GO_NEURAL_PRECURSOR_CELL_PROLIFERATION	-0.297658276436282	-1.25770107335403	0.108980431116143	0.505969836050946	65	ID4,FGFR2,PSMG1,GBX2,LHX5,POU3F2,PLXNB2,POU3F3,DAGLA,MELK,ARTN,RAB10,FZD3,C5AR1,FGF13,PCM1,KCNA1,IFT20,DOCK7
GO:0003401	axis elongation	GO_AXIS_ELONGATION	-0.383214871573927	-1.32672534044239	0.1092975616203	0.506743240239573	27	RDH10,AREG,BMP4,WNT5A,SFRP2,PTK7,FGFR2
GO:0045992	negative regulation of embryonic development	GO_NEGATIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT	-0.387188810343834	-1.32709692740976	0.109979543804852	0.508946161778647	26	SULF1,TRAF3IP1,BMP4,WNT5A,SFRP2,GATA3,CTNNB1,FZD3
GO:0030510	regulation of bmp signaling pathway	GO_REGULATION_OF_BMP_SIGNALING_PATHWAY	-0.285033612616281	-1.24237247360505	0.11016062669983	0.508946161778647	76	GDF5,ITGA3,SULF1,BMP4,WNT5A,SFRP2,HTRA1,NEO1,CYR61,SOX11,CRB2,TOB1,MSX2
GO:0033344	cholesterol efflux	GO_CHOLESTEROL_EFFLUX	-0.402633256610783	-1.33546350189329	0.110557506584723	0.508946161778647	23	APOA2,APOC1,ABCG4,ABCA7,ABCA1,APOM,ABCG1,STX12,SOAT1
GO:0030282	bone mineralization	GO_BONE_MINERALIZATION	-0.350772752325661	-1.30381053668539	0.110613454553558	0.508946161778647	36	BMP2,TUFT1,ANO6,DUOX2,ALOX15,FGFR2,EIF2AK3,LEP,RSPO2,MINPP1
GO:0006123	mitochondrial electron transport cytochrome c to oxygen	GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_CYTOCHROME_C_TO_OXYGEN	0.464943235865925	1.35853392520229	0.110881888300344	0.508946161778647	16	COX15,COX6A1,COX10,COX4I1,COX7B,COX5A,NDUFA4
GO:1902475	l alpha amino acid transmembrane transport	GO_L_ALPHA_AMINO_ACID_TRANSMEMBRANE_TRANSPORT	-0.369640930898035	-1.31354165487619	0.111113570464154	0.508946161778647	30	SLC1A6,SLC1A1,SLC7A3,SLC17A7,SLC7A8,SLC7A2,SLC25A22,SLC38A1,SLC7A4,SLC17A6,SLC7A13,SLC7A11,SLC7A14
GO:0060560	developmental growth involved in morphogenesis	GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS	-0.267523478379528	-1.22461162044801	0.111259065509452	0.508946161778647	100	SEMA3F,FLRT3,RDH10,AREG,BMP4,WNT5A,ULK2,SFRP2,FMOD,PTK7,FGFR2,EFNA5,SEMA3A,COBL,SLIT3,CSF1,FLRT1,WNT7B,EPYC,EMX1,CDK5,MAGI2,EIF2AK4,SIRT6
GO:0050995	negative regulation of lipid catabolic process	GO_NEGATIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS	-0.43515796255808	-1.35136297715985	0.111279661935204	0.508946161778647	18	APOA2,CNR1,APOC1,CIDEA,HCAR2
GO:0048662	negative regulation of smooth muscle cell proliferation	GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION	0.376146235878875	1.31686941225499	0.111289177031924	0.508946161778647	32	PPARD,MFN2,VIP,NDRG4,IGFBP3,ESR1,VIPR2,ESR2,CTNNBIP1,CDKN1B
GO:1900027	regulation of ruffle assembly	GO_REGULATION_OF_RUFFLE_ASSEMBLY	-0.428000331011563	-1.34801017083786	0.111473130891872	0.508946161778647	19	EPS8L1,NLGN1,EVL,COBL,RHOG,CORO1C,HRAS,RCC2
GO:0010976	positive regulation of neuron projection development	GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT	0.240168325979193	1.1860596903042	0.111601740097472	0.508946161778647	219	CPEB3,SHANK3,SF3A2,NLGN3,MARK2,RAPGEF1,CDKL5,NRP1,CBFA2T2,IL1RAPL1,LPAR3,PAFAH1B1,TIAM1,RAB21,TRPV2,NDRG4,P2RY2,VLDLR,MEGF8,SHANK1,NEDD4L,ZEB2,MACF1,MOB2,ARF1,GSK3B,RAPGEF2,OBSL1,DMD,RASAL1,ARHGAP35,PPP1R9A,GOLGA4,EPHA3,LIMK1,ITSN2,EZH2,GPRC5B,FGFR1,EP300,FBXO31,SETX,MTOR,IKBKB,SEMA5A,CAMK2B,CNTN1,VEGFA
GO:0048562	embryonic organ morphogenesis	GO_EMBRYONIC_ORGAN_MORPHOGENESIS	-0.218436184795215	-1.15301843372118	0.111856527825467	0.508946161778647	266	HOXA6,RPL38,RBP4,PAX8,NKX3-2,OSR1,IRX5,PDZD7,RDH10,EFEMP1,TGFBR1,IFT57,MFAP2,BMP4,WNT5A,HOXA3,MYO15A,ATP6V1B1,T,HOXA7,NEUROG1,GATA3,WNT9A,PTK7,GRHL2,FGFR2,BBS7,TMED2,FOXF1,SOX11,CRB2,MTHFD1L,GBX2,ACVR1,OTX1,ATP2B2,CTNNB1,USH1G,NR4A3,WDR19,HIF1A,HMX3,FZD3,PRKRA,SMAD2,ZIC3,SPEF2,FGF9,IFT52,DLX6,KCNQ4,ARL13B,EPHA2,WNT9B,TULP3,PKD2,HOXB8,MAFB,NODAL,SLC39A1,EDN1,STIL
NA	positive regulation of camp metabolic process	GO_POSITIVE_REGULATION_OF_CAMP_METABOLIC_PROCESS	0.294749039163669	1.25036609380758	0.111959777867316	0.508946161778647	80	GNAS,ADRB1,RXFP2,VIP,ADRB2,CALM3,ADCYAP1R1,CXCL11,GIPR,GLP1R,VIPR2,ADCY7,CXCR3,UCN,ADCY5,CALM1,RAF1,ADCY8,ADCY9,ADCY4,CXCL9,ADORA2B,PTH,CALCR,CAP2,ADM,GCG
GO:0051147	regulation of muscle cell differentiation	GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION	0.259562378039842	1.21149350278213	0.112003103233097	0.508946161778647	144	EHD1,PPARD,ZEB1,PDGFB,HDAC9,CFLAR,ANKRD2,PRICKLE1,DMPK,IGFBP3,PIN1,CAPN3,BMP10,NACA,CDH2,ZFHX3,CTNNA1,HDAC4,AKAP6,SMARCD3,CAV3,DDX39B,AKAP13,SMYD1,EZH2,MED28,SHH,EP300,MTOR,ANKRD17,IL4,TNF,NKX2-5,SCGB3A1,TRIM32,SOX9,MYLK3,HEY2,CXCL9,GDF15,FOXO4,SETD3,PROX1,TBX3,MSX1,GDF3,FLOT1,HDAC5,MEF2C,SRF
GO:0071482	cellular response to light stimulus	GO_CELLULAR_RESPONSE_TO_LIGHT_STIMULUS	-0.27612299138944	-1.23109731456673	0.112324529539969	0.508946161778647	86	NOC2L,CNGB1,KDM1A,AQP1,POLH,CRIP1,HIST3H2A,GNAT1,TP73,CDKN1A,OPN1LW,HIF1A,YY1,MME,DDB2,ZBTB1,OPN3,EIF2AK4,XPC,AURKB,BAX,RS1,CDC25A,TRIAP1,MDM2,MYC,GNGT1,SIRT1,PCNA
GO:0051968	positive regulation of synaptic transmission glutamatergic	GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC	0.44808792165313	1.3518775092842	0.112371650853185	0.508946161778647	18	SHANK3,NLGN3,NRXN1,RAB3GAP1,NPS
GO:0014061	regulation of norepinephrine secretion	GO_REGULATION_OF_NOREPINEPHRINE_SECRETION	0.455753148044567	1.35391119364517	0.112483261419432	0.508946161778647	17	P2RY1,AGT,ADRA2C,STX1A,AGTR2
GO:0006757	atp generation from adp	GO_ATP_GENERATION_FROM_ADP	0.359820065477868	1.30329021550712	0.11262378478194	0.508946161778647	37	OGDHL,PGAM2,PGAM1,OGDH,DHTKD1,PFKM,GCK,PFKFB4,PFKP,ALDOC,ALDOA,HK3,ENO2,GALK1
GO:0051279	regulation of release of sequestered calcium ion into cytosol	GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL	0.304966267609168	1.25989223222252	0.112645540857128	0.508946161778647	69	PRKACA,ANK2,CALM3,RYR2,CAPN3,XCL1,ATP1A2,HRC,CXCL11,AKAP6,DMD,CXCR3,PLN,SLC8A1,CALM1,CACNA1C,CYBA,CXCL9,PLCG1,HTT,TRDN,JPH2,PRKCE
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	GO_POSITIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	0.375172516450911	1.3134604685823	0.11321957349165	0.509623841723966	32	HMBOX1,OBFC1,MAP3K4,MAPKAPK5,TCP1,ACD,MAPK1,CCT3,CCT7,WRAP53,CCT4,PRKCQ,PKIB,MAP2K7,NEK7,ATM,MAPK3,CCT8,ATR,TNKS
GO:0051570	regulation of histone h3 k9 methylation	GO_REGULATION_OF_HISTONE_H3_K9_METHYLATION	0.4634054544131	1.35404062771551	0.113260849363442	0.509623841723966	16	SMARCB1,JARID2,ZNF304,SETD7,DMRTC2
GO:0006631	fatty acid metabolic process	GO_FATTY_ACID_METABOLIC_PROCESS	0.230973501714151	1.16931404638759	0.113278548799511	0.509623841723966	270	SLC25A17,DECR1,IVD,CYP4V2,PPARD,LPIN1,HSD17B8,CYP2D6,ACOX3,MAPKAPK2,STAT5B,SLC27A5,ACAD9,NDUFAB1,CYP2E1,ACADM,PPARA,MMAA,ACAD10,CRYL1,ACSM2A,ACOT2,FADS1,PLA2G4C,PTGR2,DLD,LIPT2,PRKAB2,THNSL2,PLA2G5,CYP2B6,QKI,CEL,NDUFS6,ABCC1,LIAS,PRKAA2,ACOT11,ECHDC2,ADIPOR2,ACSF2,PLA2G15,MGLL,MSMO1,HADH,CYP2F1,ELOVL6,ECI2,PTGDS,ETFA,PEX7,SLC27A6,GGT7,ADH7,ACOT8
GO:0043687	post translational protein modification	GO_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	-0.355390840204769	-1.30264658915998	0.113401146004531	0.509623841723966	34	ARSF,ARSH,DSCC1,SUMF2,FN3KRP,ARSI,ARSD,LCMT1,ARSK,ARSE,STT3A
GO:1901976	regulation of cell cycle checkpoint	GO_REGULATION_OF_CELL_CYCLE_CHECKPOINT	0.393953512946528	1.3223097909545	0.113876526930755	0.511077852865227	27	GSG2,CUL4A,PCID2,MAD2L1,FEM1B,DDX39B
GO:0051058	negative regulation of small gtpase mediated signal transduction	GO_NEGATIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	0.362489991433349	1.30379928525103	0.114430839002268	0.512445230656085	36	RAPGEF1,FLCN,MFN2,DLC1,STAMBP,RASAL3,RASAL1,ARHGAP35,RASAL2,SCAI,KANK1,MAPKAP1,BCL6
GO:0085029	extracellular matrix assembly	GO_EXTRACELLULAR_MATRIX_ASSEMBLY	0.462508277300227	1.35141913448638	0.114636186228046	0.512445230656085	16	GPM6B,ATP7A,THSD4,FBLN5,HAS3
GO:1904064	positive regulation of cation transmembrane transport	GO_POSITIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT	0.28734488385166	1.23953810810411	0.114637925931085	0.512445230656085	88	ANK2,DRD4,CALM3,CACNA2D1,RYR2,S100A1,CAPN3,XCL1,OPRK1,RNF207,KCNJ2,WNK2,CXCL11,ARF1,AKAP6,DMD,CXCR3,FXYD1,KCNH2,CALM1,GLRX,ANK3,CXCL9,PLCG1,HTT,TRDN,SUMO1,JPH2
GO:0050886	endocrine process	GO_ENDOCRINE_PROCESS	-0.332996852569154	-1.28306800791788	0.114927581722793	0.513058673844722	42	CMA1,DRD5,CPA3,AVPR1B,KRAS,GATA3,TACR1,AGTR1
GO:0043255	regulation of carbohydrate biosynthetic process	GO_REGULATION_OF_CARBOHYDRATE_BIOSYNTHETIC_PROCESS	0.299086036804851	1.2512742224936	0.115195862869607	0.513302721762017	74	P2RY1,AKT2,PDGFB,PPARA,GRB10,ADCYAP1R1,GSK3B,IRS1,GCK,KAT2A,PPP1R3B,PPP1R3F,MTOR,FOXO1,PPP1CB,SERPINA12,PTAFR,NFKB1,PPP1R3E,PASK,PTH,EGF,PTH1R,GCG,EPM2AIP1
GO:0060674	placenta blood vessel development	GO_PLACENTA_BLOOD_VESSEL_DEVELOPMENT	-0.376098514370011	-1.31400636523147	0.115541628969261	0.513302721762017	28	PLCD1,SPINT1,ITGB8,TMED2,CYR61,PKD2,JUNB,FBXW8,SOCS3
GO:0043393	regulation of protein binding	GO_REGULATION_OF_PROTEIN_BINDING	0.252548837337552	1.19975299342213	0.115583437892095	0.513302721762017	163	PLCL1,TFIP11,PRKACA,TMC8,NRP1,EPB41,PDGFB,APP,TIAM1,ADRB2,PPARA,PRMT7,LRRK2,LFNG,PIN1,MFNG,HIPK2,GOLGA2,NKX3-1,HDAC4,PEX14,ADD1,GSK3B,RAPGEF2,SMARCD3,CSF3,IFIT2,LRPAP1,AES,NFATC4,GTPBP4,IFIT1,EP300,MITD1,TMEM173,SPAG8,CTNNBIP1,PARK7
GO:0090596	sensory organ morphogenesis	GO_SENSORY_ORGAN_MORPHOGENESIS	-0.224123581449119	-1.16063674003883	0.115592235025433	0.513302721762017	228	RPL38,RBP4,PAX8,NKX3-2,OSR1,IRX5,CYP26B1,PDZD7,CDON,EFEMP1,MFAP2,BMP4,WNT5A,MYO15A,ATP6V1B1,WNT2B,NEUROG1,GATA3,WNT9A,PTK7,PRKCI,FGFR2,SOX11,PDE6C,GBX2,ROM1,OTX1,ATP2B2,CTNNB1,GNAT1,STAT3,USH1G,NR4A3,WDR19,HIF1A,TULP1,HMX3,FZD3,PRKRA,RDH13,NRL
GO:0045197	establishment or maintenance of epithelial cell apical basal polarity	GO_ESTABLISHMENT_OR_MAINTENANCE_OF_EPITHELIAL_CELL_APICAL_BASAL_POLARITY	-0.384147256726249	-1.31667194519795	0.115874447352792	0.513877983912384	26	EZR,WNT5A,PTK7,PRKCI,FOXF1,CRB2,PDZD11,DLG5
GO:1901797	negative regulation of signal transduction by p53 class mediator	GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	-0.388276774387556	-1.31708327012681	0.116147744501329	0.514412247357203	25	TAF9B,KDM1A,MUC1,RRM2B,BDKRB2,PSMD10,TRIAP1,MDM2,MIF,SIRT1
GO:0031099	regeneration	GO_REGENERATION	-0.243440727603455	-1.18854609016996	0.116398459867707	0.514845224592248	149	PTPRF,PAX7,APOA2,PTPN3,ANXA3,GAP43,NNMT,CEBPB,ADAM15,TSPO,ANXA1,PRMT5,SOCS1,WNT10B,F7,SULF2,IGFBP1,NR4A3,CDKN1A,MSTN,TYMS,CCNB1,TM4SF4,C5AR1,NOV,PPARG,RAPGEF3,CCNA2,DHFR,PTPRU,FAS,HMBS,HGF,MYOD1,SOX15,FLT3,TXK
GO:0051899	membrane depolarization	GO_MEMBRANE_DEPOLARIZATION	0.317600637755598	1.26680094741892	0.116721544896325	0.515000836516437	58	SCN7A,ANK2,SCN1A,CATSPER2,ATPIF1,SCN5A,CACNA2D1,TPCN1,ATP1A2,KCNJ2,SLC8A1,KCNH2,PRKCZ,CACNA1C,SCN3A,PARK7,BEST2,CACNA1B,P2RX7,CATSPER4,CACNA1E
GO:0010822	positive regulation of mitochondrion organization	GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION	0.257547588561925	1.20569656622819	0.116739642977433	0.515000836516437	147	BAD,DDHD2,FBXW7,GPHA2,C1QBP,DYNLL2,ATPIF1,RMND1,ADRB2,MOAP1,GZMB,ITGAX,RNF31,PPIF,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,GSK3B,HUWE1,CYB5R1,PSMB7,KAT2A,NMT1,SAE1,APOPT1,TNFSF10,PPP3R1,PPP1R13B,MARCH5,ARIH2,PARK7,PSMD8,USP36,PLD6,FAM162A,BID,KCNN3,OPA1,MAPK8,NSUN4,YWHAG,BAK1,AMBRA1,WBP11,TP53BP2,MPV17L2
GO:0060438	trachea development	GO_TRACHEA_DEVELOPMENT	-0.417274447421613	-1.33342661860372	0.117031460771942	0.515612430573765	20	RARA,BMP4,MAP2K2,FOXF1,CTNNB1,WNT7B,RSPO2
GO:0010669	epithelial structure maintenance	GO_EPITHELIAL_STRUCTURE_MAINTENANCE	-0.417055053969551	-1.33272553309337	0.117336060223663	0.516178309633239	20	SERPINA3,MUC2,RBP4,MUC6
GO:0090504	epiboly	GO_EPIBOLY	-0.41703516889434	-1.3326619890907	0.117466602845829	0.516178309633239	20	CYR61,TOR1A,MMP12,MSX2,SCNN1B,RHOA,PDCD10,WNT7A,RHOC,DDR1
NA	hydrogen ion transmembrane transport	GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORT	0.28112778636828	1.23143549220067	0.117639938439191	0.516266014062996	96	COX15,ATP5L,UQCRHL,COX6A1,NNT,UQCRFS1,ATP1A2,UQCRC1,ATP5A1,ATP5G2,ATP5D,COX10,ATP5O,ATP6V0E2,ATP5B,SLC4A10,COX4I1,ATP5G3,COX11,ATP6V0D2,COX7A2,COX6A2,SLC9A8,COX7B,COX7A1,ATP6AP1,COX5A,ATP1A3,NDUFA4,UQCRQ,SLC9A6
GO:0035567	non canonical wnt signaling pathway	GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY	0.263723921328861	1.21325018098833	0.117903042823035	0.516746929872835	130	PLCB2,PRICKLE1,DVL2,PSMD11,TIAM1,TNRC6C,CALM3,CAMK2A,GNG2,PSMD2,PSMC6,TNRC6A,PRICKLE2,FZD10,PSMC5,PSMB7,MED12,PSME4,CALM1,PPP3R1,TNRC6B,GNAT2,ZNRF3,PSMA8,FZD6,PSMD8,AP2M1,PSMB10,MOV10,WNT11,PSMD3,PSMB1,GNAO1,PSMA5,PSMB9
GO:0071526	semaphorin plexin signaling pathway	GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY	-0.347500309692837	-1.29164697735222	0.118412549858502	0.518305127208996	36	SEMA3F,SEMA3C,MET,SEMA3A,SEMA3B,PLXNB2,PLXNA2,SEMA3D,SEMA3E,SEMA4B,SEMA4A,PLXNA4,PLXNB1,RAC1,PLXNA1,SEMA7A
NA	movement in environment of other organism involved in symbiotic interaction	GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION	-0.286159192624976	-1.23480220066913	0.118995254080333	0.520134380078209	72	CLDN1,CD55,TYRO3,DPP4,EFNB3,WWP2,HAVCR1,SLC10A1,ANPEP
GO:0014742	positive regulation of muscle hypertrophy	GO_POSITIVE_REGULATION_OF_MUSCLE_HYPERTROPHY	0.422814258915965	1.33075936330019	0.119317867227728	0.520134380078209	21	AGT,PDE5A,PIN1,BMP10,AKAP6,DDX39B,MTOR
GO:0045814	negative regulation of gene expression epigenetic	GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC	0.285206807524827	1.23254564525468	0.119630460880004	0.520134380078209	89	HILS1,HIST1H2AB,JARID2,HDAC2,DYDC1,SUV39H1,HIST1H3G,HIST1H3B,EED,HELLS,SIRT4,HIST1H4F,SIRT5,RRP8,H2AFZ,H3F3A,EZH2,MBD3L1,H2AFV,HIST1H3E,SPI1,MSL3P1
GO:0046189	phenol containing compound biosynthetic process	GO_PHENOL_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	-0.365347500917663	-1.29828468885835	0.119657362934107	0.520134380078209	30	HDC,TPH1,GATA3,PMEL,SNCA,DDC,SLC6A3
GO:0090092	regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	-0.229680793958497	-1.16729469961751	0.119701696978921	0.520134380078209	197	VASN,GDF5,CDKN2B,ITGA3,SULF1,SNW1,TGFBR1,BMP4,WNT5A,SFRP2,BMP2,NPNT,HTRA1,DMRT1,NEO1,SNX25,CYR61,SOX11,SKIL,CRB2,CIDEA,GDF10,ACVR1,MEN1,TOB1,MSX2,LEFTY1,UBA52,MSTN,BMP5,DAB2,SMAD2,NOV,SMURF2,FGF9,MAGI2,IL17F,ONECUT1,CTDSPL2,THBS1,PDPK1,ACVR2B,ZNF703
NA	zinc ii ion transport	GO_ZINC_II_ION_TRANSPORT	-0.386411260698624	-1.31075521490445	0.120080859572411	0.520134380078209	25	SLC39A8,SLC39A6,SLC39A2,SLC30A2,SLC39A10,SLC30A8,SLC30A9,SLC39A1,SLC39A4,SLC30A7,SLC30A4
GO:0048589	developmental growth	GO_DEVELOPMENTAL_GROWTH	-0.212048598678676	-1.13864930774103	0.120132137293871	0.520134380078209	307	SEMA3F,MATN1,PAX7,TARBP2,LIPC,RARA,FLRT3,RDH10,AREG,BMP4,WNT5A,ULK2,SFRP2,FMOD,GAP43,GAS1,FGF7,DUOX2,GATA3,THBS3,HELT,PTK7,GRHL2,FGFR2,EFNA5,ADAM15,TMED2,COMP,SEMA3A,ANXA1,COBL,WNT10B,BMPR1B,IGFBP1,SLIT3,OSTN,CSF1,FLRT1,SLC25A25,MSX2,WNT7B,EPYC,MSTN,EMX1,TYMS,LEP,CCNB1,TM4SF4,SMAD2,CDK5,RSPO2,NOV,MAGI2,EIF2AK4,SIRT6,EIF4H,GINS4,XRCC2,MYOD1,SOX15,SPTBN2,ACVR2B,TXK,ALKBH1,BNC2,SALL4,GPR149,PYGO2,STIL,RAD51B,FOXO3,CDC42,UNC79,PTPN12,POU4F2,PDLIM5,PLXNB1,ABL1,EYS,NBN,G6PC,STRA6,TAL2,FOXL2
GO:0060420	regulation of heart growth	GO_REGULATION_OF_HEART_GROWTH	0.346707998105919	1.28461473466433	0.120303468208092	0.520134380078209	41	TBX2,PIN1,BMP10,GJA1,AKAP6,CAV3,DDX39B,TGFBR2,FGFR1,ERBB4,MTOR,TBX5,TBX20,NKX2-5,CDK1,HEY2,ACACB
GO:0070670	response to interleukin 4	GO_RESPONSE_TO_INTERLEUKIN_4	-0.365036854806493	-1.29718078890345	0.120343522432989	0.520134380078209	30	GATA3,RPL3,IMPDH2,XBP1,KEAP1,IL24,MCM2,FASN
GO:0030397	membrane disassembly	GO_MEMBRANE_DISASSEMBLY	0.346692685784819	1.28455799979402	0.120375722543353	0.520134380078209	41	LPIN1,POM121,PAFAH1B1,NUP85,RAE1,NUP188,NEK9,EMD,CDK1,BANF1,TPR,AAAS,POM121C,AKAP8L,CTDNEP1,NUP214,PLK1,NUP35
NA	organ regeneration	GO_ORGAN_REGENERATION	-0.278279098074766	-1.22467980942884	0.121041962767073	0.522298944844881	80	APOA2,PTPN3,ANXA3,NNMT,CEBPB,PRMT5,SOCS1,F7,SULF2,NR4A3,CDKN1A,TYMS,C5AR1,PPARG,RAPGEF3,CCNA2,PTPRU,FAS,HMBS,HGF
GO:0002275	myeloid cell activation involved in immune response	GO_MYELOID_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	-0.335328850071911	-1.27692433399148	0.121187010078387	0.522298944844881	40	MRGPRX2,CCL3,ANXA3,PYCARD,NR4A3,STXBP3,SNAP23,VAMP8,LAT
GO:0006575	cellular modified amino acid metabolic process	GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS	-0.231171316473256	-1.16907434101783	0.121363279568531	0.52238976857759	190	PLA2G2A,ASS1,CHDH,CHAC2,SHMT1,LIPC,GSTZ1,ALDH1L1,OCLN,CKMT1A,MGST1,DUOX2,PEMT,GART,TG,GSTM3,EEF1G,MTHFD1L,CHAC1,PLA2G16,PLA2G2D,PDZD11,CLIC3,CPS1,PADI4,TYMS,PLA2G4F,SERINC2,DHFR,GGT1,GGCT,FASN,LPCAT3,FTCD,DDAH2
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	GO_REGULATION_OF_CELL_PROLIFERATION_INVOLVED_IN_HEART_MORPHOGENESIS	0.467494233122571	1.34332947401872	0.121600773248573	0.522743553965132	15	HAND2,BMP10,NACA,EYA1,SIX1,TBX5,SOX9
GO:0002708	positive regulation of lymphocyte mediated immunity	GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.308027490571482	1.253761904478	0.122399929309888	0.525507859766687	64	RSAD2,STAT5B,CRTAM,UNG,XCL1,HSPD1,CD40,HLA-B,PRKCZ,IL4,TNF,EXOSC3,P2RX7,SH2D1B,MALT1,IL2,ZP3,SH2D1A,TNFSF4,IL21,PAXIP1,AP1G1,HLA-E,IL12RB1,FOXP3,STX7,RASGRP1
GO:0033604	negative regulation of catecholamine secretion	GO_NEGATIVE_REGULATION_OF_CATECHOLAMINE_SECRETION	0.457590088818767	1.33704850730614	0.122739522349224	0.526294563347119	16	P2RY1,DRD2,ADRA2C,GCK,AGTR2,GABBR1
GO:0001890	placenta development	GO_PLACENTA_DEVELOPMENT	-0.24755550442347	-1.18909150531395	0.12328197603326	0.527948004234037	134	CCNF,KRT8,KRT19,PTGIS,LHX4,PLCD1,SPINT1,CUL7,ITGB8,HTRA1,CEBPB,GRHL2,FGFR2,TMED2,CYR61,MEN1,CEBPA,EGFR,WNT7B,HIF1A,ST14,LEP,STK3,PPARG,ETV2,DCN,ALKBH1,TTPA,PKD2,NODAL,JUNB,RPS6,FBXW8,SOCS3,ESRRB,IL10,PLA2G4A
GO:0001654	eye development	GO_EYE_DEVELOPMENT	-0.211038143388596	-1.13494026869783	0.124356798405129	0.53077735106223	311	WNT6,RBP4,IRX5,TRAF3IP1,RARA,WT1,RDH10,CDON,EFEMP1,TGFBR1,MFAP2,BMP4,WNT5A,GPM6A,SIX6,PAX4,WNT2B,GATA3,WNT9A,GRHL2,PRKCI,PRSS56,BBS7,SOX11,PDE6C,SKIL,IMPDH2,ROM1,KLF4,MAB21L2,PRPH2,CTNNB1,GNAT1,BMPR1B,STAT3,SLC17A7,WDR19,EGFR,SLC25A25,WNT7B,HIF1A,TULP1,ATF6,ADAMTS18,RDH13,NRL,ZNF513,FGF9,BCAR3,BAX,EPHA2,ACVR2B,RS1,ARHGEF15,WNT9B,TULP3,NPHP1,SHROOM2,PITX3,RP1L1,PYGO2,NKD1,NEUROD4,POU4F2,GNGT1,DLG1,INHBA,SIPA1L3,AXIN1,PSEN1,RET,LAMC3,PTF1A,STRA6,ATOH7,ATP2B1,FOXL2,HPCA,CHRDL1,SERPINF1,GRM6,ABCB5,SDK2,SLC7A11,WNT7A,SMOC1,TSKU,BLOC1S3,PRDM1,JUN,IFT140,CYP1B1,BFSP1,TWSG1,ATP8A2
GO:0019682	glyceraldehyde 3 phosphate metabolic process	GO_GLYCERALDEHYDE_3_PHOSPHATE_METABOLIC_PROCESS	-0.444192997655396	-1.33468818208678	0.124466956728792	0.53077735106223	16	KHK,PGLS,ALDOB
GO:0015936	coenzyme a metabolic process	GO_COENZYME_A_METABOLIC_PROCESS	0.44827920931909	1.33170827668353	0.124479244160095	0.53077735106223	17	PANK3,MCCC2,HMGCR,COASY,PANK4,ACACB,MCEE
GO:1904356	regulation of telomere maintenance via telomere lengthening	GO_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	0.331439243158541	1.27101190170173	0.124725768746628	0.53077735106223	48	HMBOX1,SMG6,MCRS1,OBFC1,MAP3K4,MAPKAPK5,TCP1,ACD,MAPK1,CCT3,CCT7,WRAP53,CCT4,PRKCQ,PKIB,MAP2K7,HNRNPU,NEK7,ATM,MAPK3,CCT8,ATR,NAT10,TNKS,HNRNPC,DKC1
GO:0023061	signal release	GO_SIGNAL_RELEASE	-0.238297168957739	-1.17548939400096	0.125090131529874	0.53077735106223	160	STX19,SMPD3,SYT4,SNAP25,NLGN1,UBE2Q1,SYN1,ILDR2,SYTL1,GATA3,SYT17,TRIM9,ANXA1,RPH3A,PDZD11,C2CD4D,SYN3,STXBP3,SNAP23,PCLO,EIF2AK3,LEP,STX11,SYT6,SLC18A2,SMAD2,CDK5,UNC13B,LIN7B,GPR119,SLC30A8,SYT5,STX2,STXBP1,GAL,ACVR2B,CARTPT,CASK,SLC32A1,CYB5R4,TMF1,EDN1,SYTL5,SNAPIN,INHBA,SLC6A9,PSEN1,SLC18A3,SYT1
GO:0018958	phenol containing compound metabolic process	GO_PHENOL_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.283700863503819	-1.22751944151512	0.125115719311239	0.53077735106223	73	HDC,TPH1,NPR1,SNCAIP,DUOX2,GATA3,LRTOMT,TG,PMEL,SNCA,ATP2B2,GRIN2A,DDC,SLC6A3,STAR
GO:0051924	regulation of calcium ion transport	GO_REGULATION_OF_CALCIUM_ION_TRANSPORT	0.242740189563618	1.17914057796007	0.125407516507521	0.53077735106223	193	AGT,PRKACA,CACNA2D4,OPRL1,PDGFB,ANK2,LPAR3,DRD4,ADRB2,TRPV2,CALM3,CAMK2A,CACNA2D1,RYR2,S100A1,CAPN3,XCL1,ATP1A2,LGALS3,DRD2,HRC,ADCYAP1R1,CXCL11,GJA1,AKAP6,CAV3,DMD,CXCR3,UCN,PLN,STC2,SLC8A1,CALM1,AHNAK,CAMK2G,MYLK,CACNA1C,TSPAN13,SEMG1,CAMK2B,HOMER1,CACNA1B,P2RX7,CYBA,CXCL9,PLCG1,ZP3,SLC30A1,GNAO1,HTT,TRDN,SUMO1,JPH2,LILRB1,PRKCE
GO:0032784	regulation of dna templated transcription elongation	GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION	0.354580337868737	1.28431160263896	0.125531799337401	0.53077735106223	37	ELL3,PAF1,ELL,DDX39B,TCEA2,EZH2,SHH,RECQL5,HMGN1,LDB1,HTATSF1,RNF168,GTF2F2
GO:0042475	odontogenesis of dentin containing tooth	GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH	-0.284280438802366	-1.22669521192139	0.125662692441255	0.53077735106223	72	FAM20A,SLC34A1,AMBN,WNT6,DLX1,BMP4,BMP2,HTRA1,EDAR,CTNNB1,MMP20,MSX2,FGF4
GO:0046717	acid secretion	GO_ACID_SECRETION	-0.294980388018832	-1.23952947263757	0.125683688008457	0.53077735106223	63	SLC1A6,NMU,SNAP25,NMB,SLC1A1,ANXA1,SLC38A2,ABCB11,SLC17A7,LEP,PLA2G4F,UNC13B,BDKRB2,AGXT,STXBP1,CACNB4,GRM2,SLC6A9,AQP9,ABCC4,SYT1,PLA2G4A
GO:0030199	collagen fibril organization	GO_COLLAGEN_FIBRIL_ORGANIZATION	-0.352582705214945	-1.2830997985957	0.125770134302558	0.53077735106223	33	ADAMTS3,TGFBR1,SFRP2,FMOD,SERPINH1,ANXA2,TNXB,LOX,COL12A1,COL11A2,COL11A1,CYP1B1,ADAMTS14,FOXC1,LUM
GO:0010324	membrane invagination	GO_MEMBRANE_INVAGINATION	-0.341425631419468	-1.27700280147614	0.125834915670725	0.53077735106223	37	IGHG4,IGHG2,IGHG1,ABCA1,IGHD,THBS1,IGKC,IGLL1,IGLC1,RAC1,HGS,IGHA1,DOCK1,MYH9,VAMP7,FCGR1A,SMURF1,IGLL5
GO:0051168	nuclear export	GO_NUCLEAR_EXPORT	0.259794533785641	1.20189218115424	0.126137093774306	0.531386054623672	135	NOL6,ADAR,POM121,HSPA9,NCBP1,SMG6,XPO7,TSC1,STRADA,NUP85,SMG1,RAE1,GSK3B,STRADB,DDX39B,SRSF4,AKAP13,NMD3,XPO4,CPSF1,NUP188,NCBP2,HNRNPA2B1,RNPS1,SRSF1,ALKBH5,MALT1,ATXN1,ENY2,TPR,AAAS,DHX38,NXF3,RBM8A,POM121C,CHTOP
GO:0045823	positive regulation of heart contraction	GO_POSITIVE_REGULATION_OF_HEART_CONTRACTION	0.362634611190604	1.28736640127506	0.126655267753201	0.532902039071595	34	TRPM4,ADRB1,ADRB2,RYR2,HRC,RNF207,TACR3,UCN,ADA,NKX2-5,ACE2,HEY2,ATP2A2,ADM
GO:0030316	osteoclast differentiation	GO_OSTEOCLAST_DIFFERENTIATION	-0.374714705016509	-1.2972969773849	0.127073283552501	0.533993348861072	27	TNFSF11,ANXA2,CTNNB1,CSF1,SNX10,SH3PXD2A,EPHA2,JUNB,OSTM1,FAM20C
GO:0042423	catecholamine biosynthetic process	GO_CATECHOLAMINE_BIOSYNTHETIC_PROCESS	-0.442734124600444	-1.33030463566464	0.127237699417711	0.534017576359122	16	HDC,GATA3,SNCA,DDC,SLC6A3
GO:0055070	copper ion homeostasis	GO_COPPER_ION_HOMEOSTASIS	0.464010099091613	1.33331792819931	0.127400137549025	0.534033453287694	15	ATP7A,SCO1,APP,CUTC,ARF1
GO:0055025	positive regulation of cardiac muscle tissue development	GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.379785701057635	1.29800795074956	0.128004818661361	0.535181505612015	29	TBX2,PIN1,BMP10,AKAP6,DDX39B,FGFR1,ERBB4,MTOR,TBX5,TBX20,CDK1,HEY2
GO:1901017	negative regulation of potassium ion transmembrane transporter activity	GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.463726149206706	1.33250200744027	0.128069294968308	0.535181505612015	15	NEDD4L,CAV3,KCNRG,ANK3,SUMO1,CASQ2,ACTN2,KCNAB1,KCNQ1,CAB39
GO:0015800	acidic amino acid transport	GO_ACIDIC_AMINO_ACID_TRANSPORT	-0.404649645585946	-1.31003907894944	0.128265566686309	0.535181505612015	21	SLC1A6,SLC1A1,SLC17A7,PRAF2,SLC25A22,ARL6IP5,SLC17A6,PSEN1,SLC7A11
GO:0010310	regulation of hydrogen peroxide metabolic process	GO_REGULATION_OF_HYDROGEN_PEROXIDE_METABOLIC_PROCESS	-0.452272971178338	-1.33238135207097	0.128389931389737	0.535181505612015	15	HP,ZNF205,SNCA,STAT3,NOXA1,PTGER4,NOXO1,RAC1
GO:0050685	positive regulation of mrna processing	GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING	0.379479339173221	1.29696088615322	0.128570646321208	0.535181505612015	29	CPEB3,PAF1,SNRNP70,NCBP1,TNRC6C,SF3B4,TNRC6B,THRAP3,NCBP2,PRPF19
GO:0045652	regulation of megakaryocyte differentiation	GO_REGULATION_OF_MEGAKARYOCYTE_DIFFERENTIATION	-0.411352361459615	-1.31450222218265	0.128627997041034	0.535181505612015	20	KDM1A,HIST1H4C,HIST1H4D,SCIN,HIST1H4E,HMGB2,TESC,PF4
GO:0050775	positive regulation of dendrite morphogenesis	GO_POSITIVE_REGULATION_OF_DENDRITE_MORPHOGENESIS	0.37568792367474	1.29480037648779	0.128887510716305	0.535599211198868	30	CDKL5,IL1RAPL1,PAFAH1B1,TIAM1,RAB21,OBSL1,FBXO31,CAMK2B,EPHA4,BHLHB9,MARCKS,ITPKA
GO:0045911	positive regulation of dna recombination	GO_POSITIVE_REGULATION_OF_DNA_RECOMBINATION	0.44605158046619	1.32509063366303	0.129184645142092	0.536172029036106	17	UNG,CD40,IL4,EXOSC3,PRDM9,IL2,TNFSF4,UBE2B,PAXIP1
GO:1903541	regulation of exosomal secretion	GO_REGULATION_OF_EXOSOMAL_SECRETION	-0.441614994226205	-1.32694193050586	0.129488927852458	0.536773067920411	16	ATP13A2,SMPD3,SDC1,SNF8
GO:0046620	regulation of organ growth	GO_REGULATION_OF_ORGAN_GROWTH	0.298769458976315	1.23718790408285	0.129655099449852	0.536800817648464	70	TBX2,HLX,PIN1,CACNA2D2,YAP1,BMP10,GJA1,AKAP6,CAV3,PTEN,DDX39B,TGFBR2,LATS1,FGFR1,ERBB4,MTOR,TBX5,TBX20,FLVCR1,NKX2-5,CDK1,SOD1,HEY2,ACACB,FXN
GO:0016052	carbohydrate catabolic process	GO_CARBOHYDRATE_CATABOLIC_PROCESS	0.273713900570138	1.21275613322208	0.130109473321265	0.538020254544692	103	LRP5,CHIT1,BAD,OGDHL,PYGB,PYGM,PGM5,CALM3,CRYL1,PGAM2,PGAM1,PHKG1,FUT5,OGDH,DHTKD1,MANBA,PFKM,GCK,NEU3,CALM1,PFKFB4,PFKP,PHKA2,PHKB,ALDOC,FUT4,ALDOA,HK3,ENO2,GALK1,GYG1
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to dna damage	GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE	-0.364697801341321	-1.28510709988974	0.130775185226142	0.539971118199845	29	TAF9B,KDM1A,SFRP2,MUC1,SKIL,TPT1,RPS3,TRIAP1,MIF,SIRT1
GO:1901615	organic hydroxy compound metabolic process	GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS	-0.199274996768678	-1.11217342649405	0.130902089260568	0.539971118199845	449	SMPDL3B,PLA2G2A,PLCH2,CFTR,SLC34A1,CHDH,HDC,RBP4,PLCD1,TPH1,APOA2,LRP2,SMPD3,APOC1,MTMR7,ALDH3B1,SHMT1,HAO1,ACADL,LIPC,DEGS2,NPR1,RDH10,LRAT,SRD5A3,BCHE,CYP11A1,SNCAIP,SLC22A4,FGF7,FDX1L,DUOX2,GATA3,LRTOMT,PEMT,LDHA,ALOX15,TG,PMEL,SGPP2,NPC1L1,SMPDL3A,PLCB3,ALDH3A2,SNCA,PLA2G16,ABCB11,SMPD2,PLA2G2D,FDXR,ATP2B2,GK,CAT,GRIN2A,DDC,ANGPTL3,CEBPA,AKR1C3,DGAT2,SLC6A3,STAR,RDH8,HIF1A,CYP21A2,SCAP,MBTPS2,LEP,PLA2G4F,PSAT1,RDH13,INPP5E,DPAGT1,SORL1,PCK1,SGMS2,ABCA1,MINPP1,PLTP,LIPE,NUDT11,CYP4F2,MVK,INPP5K,LPCAT3,SLCO1B3,CROT,SLC44A5,ALDH3B2
GO:2000826	regulation of heart morphogenesis	GO_REGULATION_OF_HEART_MORPHOGENESIS	0.381408345976343	1.29237570347685	0.131334003840176	0.541089665760136	28	TBX2,HAND2,RNF207,BMP10,NACA,EYA1,SIX1,TBX5,SOX9,TGFB3,TWIST1,SMO,FOXC2,GNG5,DKK1
GO:2001235	positive regulation of apoptotic signaling pathway	GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY	0.250322485515347	1.18534941599598	0.131624732334047	0.541624509824453	159	AGT,BAD,SIAH1,RBCK1,FBXW7,DYNLL2,ATPIF1,MOAP1,GZMB,PPIF,PINK1,CTSH,CTNNA1,NKX3-1,OSM,PLAGL2,GSK3B,JAK2,PTEN,FBXO18,AGTR2,NFATC4,NMT1,BCL2L14,APOPT1,TNFRSF10B,TNFSF10,PPP3R1,PPP1R13B,G0S2,DAPK3,PARK7,MAL,TIMP3,SOD1,FAF1,SFPQ,FAM162A,MAGED1,HYAL2,SMAD3,FASLG,BID,PIAS4,MAPK8,MSX1,YWHAG,BAK1,TP53BP2,ING5,LTBR,CASP2,HRK,STK4,BMF
GO:0006730	one carbon metabolic process	GO_ONE_CARBON_METABOLIC_PROCESS	-0.350239405921382	-1.27457219129351	0.132064181552236	0.542646416609323	33	CA12,SHMT1,CA9,ALDH1L1,MTHFD1L,TYMS,CA3,DHFR,FTCD,CA5A,ALDH1L2
NA	coenzyme metabolic process	GO_COENZYME_METABOLIC_PROCESS	0.232769817697613	1.16128258448462	0.132421056053046	0.542646416609323	238	IDH3B,ME1,PANK3,DLAT,AGK,OGDHL,ATPIF1,MCCC2,ACOT6,ACSM2A,ACOT2,NNT,DLD,PGAM2,PGAM1,LIPT2,RPIA,MTHFR,OGDH,HAAO,DHTKD1,HMGCR,FPGS,COASY,PDHA1,MVD,LIAS,ACOT11,NMNAT3,PFKM,SARDH,ACSF2,GCK,SLC5A6,COQ9,SUCLG2,MDH2,MDH1,NFS1,ELOVL6,PFKFB4,PDHX,PFKP,ALDOC,PANK4,SLC25A32,ACOT8,MOCS2,VCP,PDHB,ALDOA,HK3,ENO2,GALK1,IDH1,GPHN,RFK,THTPA,ACACB,GCDH,TPK1
GO:0030307	positive regulation of cell growth	GO_POSITIVE_REGULATION_OF_CELL_GROWTH	0.258109545659052	1.19529719415756	0.132492646810237	0.542646416609323	136	DDX3X,CDKL5,NRP1,LPAR3,NCBP1,CSNK2A1,PAFAH1B1,TRPV2,KDM2B,PIN1,MEGF8,NEDD4L,IL9,MACF1,GSK3B,AKAP6,EXOSC4,RASAL1,UCN,DDX39B,GOLGA4,LIMK1,ITSN2,H3F3A,EP300,MTOR,SEMA5A,VEGFA,TRIM32,CYBA,HYAL1,IL2,CD38,FXN,ADAM10,L1CAM,BCL11A,HPN,CPNE9,NTRK3,CDKN2AIP,PPP1R1C,SRF
GO:0015701	bicarbonate transport	GO_BICARBONATE_TRANSPORT	-0.324602738567014	-1.25663519214015	0.132517930615824	0.542646416609323	43	SLC26A9,CFTR,CA12,CA9,AQP1,BEST1,SLC4A4
GO:0060147	regulation of posttranscriptional gene silencing	GO_REGULATION_OF_POSTTRANSCRIPTIONAL_GENE_SILENCING	0.436619775145267	1.31727820725446	0.132926082032048	0.543120950459313	18	ADAR,WTIP,ESR1,NCOR1,LIMD1
GO:0010823	negative regulation of mitochondrion organization	GO_NEGATIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION	0.357392335097816	1.27694694738813	0.13323032175968	0.543120950459313	35	PARL,FLCN,LRRK2,PPIF,PINK1,SIAH3,SIRT4,LIG3,BAG4,FXN,OPA1
GO:0014074	response to purine containing compound	GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND	-0.241164604828706	-1.17382697462764	0.133241623268154	0.543120950459313	146	ASS1,CFTR,P2RX1,EZR,FOXM1,WT1,ALDOB,AQP1,AREG,RYR1,PAX4,DUOX2,GPD1,LDHA,SDC1,AQP8,PKLR,WNT10B,SLC6A3,STAR,HIF1A,CPS1,ADIPOQ,PPARG,SPARC,RAPGEF3,RYR3,ITPR3,AGXT,INPP5K,SLC8A3,ASPH
GO:0021871	forebrain regionalization	GO_FOREBRAIN_REGIONALIZATION	-0.385629129473899	-1.29463623101811	0.133279235020616	0.543120950459313	24	BMP4,BMP2,WNT2B,FEZF1,WNT7B,EMX1
GO:0051092	positive regulation of nf kappab transcription factor activity	GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY	-0.2508923548821	-1.18506926901902	0.133739709060884	0.544267803720066	121	EDA2R,TNFSF11,PRKD1,WNT5A,KRAS,PRKCI,ALK,TRAF5,RIPK4,MID2,CARD14,IRAK1,TRIM62,CAT,S100A12,PYCARD,RIPK2,RIPK1,CHUK,TRADD,UBA52,RIPK3,IRAK3,RHEBL1,TRIM38,RPS3,IKBKG,S100A9
GO:0009582	detection of abiotic stimulus	GO_DETECTION_OF_ABIOTIC_STIMULUS	-0.25477874330291	-1.19062137799155	0.133884058669107	0.544267803720066	113	TRPM3,LXN,CNGB1,MMP24,PDZD7,PKD1L3,BEST1,GUCY2F,PIEZO2,PDE6C,ANO3,TACR1,ATP2B2,PKDREJ,GNAT1,NPFFR2,CACNA1F,OPN1LW,TULP1,AIPL1,OPN3,TMC2,KCNA1,TIMELESS,CACNB4,RS1,PKD2,PITPNM1,GUCA1A,GNGT1,PAWR,EYS,GRM6,TRPA1,HTR2A,COL11A1,CDS1,ATP8A2,PDE6G,PDE6A,RCVRN,DRGX,OPN1SW,CALCA,CHRNA10,GRK1,ADORA1,IGF1
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to dna damage	GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE	-0.390957762362484	-1.29673794661647	0.134262510974539	0.545147903426174	23	TAF9B,KDM1A,SFRP2,MUC1,TPT1,TRIAP1,MIF,SIRT1
GO:0002407	dendritic cell chemotaxis	GO_DENDRITIC_CELL_CHEMOTAXIS	-0.438769024083112	-1.31839050638029	0.134597484685153	0.545849558373764	16	CCL19,ARHGEF5,CCR6,ANO6,CCL21
GO:0006910	phagocytosis recognition	GO_PHAGOCYTOSIS_RECOGNITION	-0.390687140932616	-1.29584034306166	0.13476733977173	0.545880704779352	23	COLEC12,TULP1,FCN3,IGHG4,IGHG2,IGHG1,IGHD,IGKC,IGLL1,IGLC1
GO:0061041	regulation of wound healing	GO_REGULATION_OF_WOUND_HEALING	-0.251008992224212	-1.1842273230616	0.134939291859535	0.545920260095187	120	VTN,PRKCA,ANO6,FAP,C1QTNF1,ANXA5,SERPING1,ANXA1,ANXA2,INSL3,F7,HPSE,F2,PLAUR,ADAMTS18,HOPX,SERPINB2,S100A9,PROS1,CD34,STX2,MYOD1,SOX15,THBS1,F2R,TXK,CASK,ABAT,EDN1,NFE2L2,SCARA5,PTGER4,F3,STAB2,SERPINC1,FGF2,THBD,HRAS,ZAP70
GO:0045214	sarcomere organization	GO_SARCOMERE_ORGANIZATION	0.393612399139328	1.29589116903967	0.135471912792938	0.546454152395763	25	OBSCN,LDB3,CAPN3,BMP10,TCAP,PRKAR1A,MYPN,TTN,NKX2-5,FHOD3,MYLK3,CFL2,SRF,CASQ2,ACTN2
GO:0042742	defense response to bacterium	GO_DEFENSE_RESPONSE_TO_BACTERIUM	-0.226692662882817	-1.15468588406797	0.135589774864054	0.546454152395763	200	PLA2G2A,SLPI,DEFA5,PRB3,ANXA3,DEFB123,MUC5B,HP,DEFB124,CEBPB,DEFA6,DEFB133,HIST1H2BE,HIST1H2BK,S100A12,DEFB132,PYCARD,RIPK2,KLK3,SEMG2,TNFRSF1A,IGHG4,IGHG2,IGHG1,C5AR1,S100A9,IFNE,DEFB121,MBL2,PGLYRP1,CLEC4E,IGHD,TLR9,NOD1,IGKC,HMGB2,DEFB114,DROSHA,TLR2,IGLL1,TMF1,IGLC1,CEBPE,HIST1H2BF,ELANE,LALBA,CARD9,STAB2,IL10,FAU,LYZ,GALP,WFDC12,PGLYRP2,CAMP,TLR3,LPO,LTF,SEH1L
GO:0055090	acylglycerol homeostasis	GO_ACYLGLYCEROL_HOMEOSTASIS	-0.379022196907368	-1.28569058847472	0.135923183406209	0.546454152395763	25	LIPC,SESN2,XBP1,ANGPTL3,DGAT2,LPL,ANGPTL4,NR1H3,HNF4A,MED13,SIRT1
GO:0061098	positive regulation of protein tyrosine kinase activity	GO_POSITIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY	0.356425325381646	1.27349186460125	0.135975277222323	0.546454152395763	35	AGT,FBXW7,PDGFB,DVL2,UNC119,ADRA2C,TGFA,GPRC5B
GO:0048754	branching morphogenesis of an epithelial tube	GO_BRANCHING_MORPHOGENESIS_OF_AN_EPITHELIAL_TUBE	-0.246640350220919	-1.17867712060745	0.136036146049579	0.546454152395763	130	WNT6,PAX8,WT1,RDH10,AREG,BMP4,WNT5A,SFRP2,BMP2,MET,NPNT,KRAS,FGFR2,FOXF1,FOXA1,GBX2,ACVR1,CTNNB1,DLG5,CSF1,MSX2,RSPO2,GDNF,TIMELESS,SEMA3E,BAX,EPHA2,WNT9B,PPP1CA,PKD2,GNA13,MYC,EDN1,MYCN,DLG1,ADAMTS16
GO:0006650	glycerophospholipid metabolic process	GO_GLYCEROPHOSPHOLIPID_METABOLIC_PROCESS	0.225811490643502	1.1483770853164	0.136105950932035	0.546454152395763	281	PIK3C2B,CHAT,PIK3R1,MTMR1,LPIN1,DDHD2,PDGFB,PCYT1A,ACP6,TAZ,PAFAH1B1,DBI,CHPT1,PLD1,PLA2G4C,DRD2,LCAT,PLA2G5,SERINC5,SMG1,INPP5J,PIP5K1B,ARF1,INPPL1,LPCAT4,IMPA2,AGPAT3,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,INPP5D,PIK3C3,INPP1,PIP4K2C,IRS1,IP6K3,PLA2G15,PIKFYVE,SMPD4,PI4K2A,GPAA1,PIP4K2B,IP6K2,FGFR1,AGPAT1,CDS2,ERBB4,MBOAT2,PCYT1B,PIK3R5,PIK3C2G,MPPE1,HADHB,PLA2G4E,PLD6,EFR3B,PIGM,CETP,LCLAT1,FAM126A,CD80,PIP5K1C,GAB1,FGF6,TTC7B,VAC14,HADHA,FGF8,INPP5A,GPCPD1,MTMR14,PNPLA6,EGF,SLC27A1,SACM1L,INPP5F,CHKA,TAMM41,MBOAT1,DPM2,PLA2G4D,PIGS,TMEM150A,APOA5,MTMR2,PCYT2,EFR3A,PIK3R6,CDIPT,PIK3R2,PIK3CB,PLA1A,EREG
GO:0006826	iron ion transport	GO_IRON_ION_TRANSPORT	-0.309542304304735	-1.23972414668707	0.136207674943567	0.546454152395763	50	STEAP3,STEAP1,ATP6V1C2,ATP6V1B1,ATP6V0D1,ATP6V1H,FTHL17,ATP6V1A,STEAP1B,TTYH1,SCARA5,SLC25A37
GO:0006352	dna templated transcription initiation	GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION	0.242230518302847	1.17146096516339	0.13645466130447	0.546793321370055	186	NR1I2,NR3C2,PPARD,ESRRA,BRF1,ZNRD1,NOTCH3,NR2F6,PPARA,TWISTNB,ESR1,CREBBP,DACH2,TCF4,YAP1,TAF1,MED7,BRF2,MED27,TEAD2,MED24,HIST1H4F,DACH1,MED25,MED12,RXRB,GTF2H3,AR,TAF1B,RXRG,MED17,POLR2I,ESR2,THRAP3,TBX5,MAZ,RXRA,POLRMT,ESRRG,GTF2H5,TFB2M
GO:0002706	regulation of lymphocyte mediated immunity	GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.270371960596584	1.20374881559191	0.136953082003302	0.548138019052455	106	TRPM4,RSAD2,STAT5B,CRTAM,UNG,XCL1,SPN,CEACAM1,HSPD1,CD40,HLA-B,PRKCZ,CR1,IL4,TNF,MICA,EXOSC3,P2RX7,SH2D1B,MALT1,IL2,ZP3,HMGB1,BTK,SH2D1A,CLC,LILRB1,BCL6,FOXJ1,TNFSF4,IL21,PAXIP1,PIK3R6,AP1G1,HLA-E,TAP1,SUSD4,IL12RB1,FOXP3,PPP3CB,STX7,RASGRP1
NA	regulation of camp metabolic process	GO_REGULATION_OF_CAMP_METABOLIC_PROCESS	0.263652740096547	1.19720219341927	0.137391984758794	0.548853186816319	119	GNAS,OPRL1,ADRB1,RXFP2,DRD4,VIP,ADRB2,CALM3,DRD2,ADCYAP1R1,CXCL11,GIPR,GLP1R,AKAP6,VIPR2,ADCY7,CXCR3,UCN,ADCY5,PDE2A,EGLN1,CALM1,RAF1,P2RY13,ADCY8,ADCY9,HTR1E,CCR2,GABBR1,ADCY4
GO:0048762	mesenchymal cell differentiation	GO_MESENCHYMAL_CELL_DIFFERENTIATION	-0.246880641675296	-1.17799948321216	0.137457883685727	0.548853186816319	129	SEMA3F,SEMA3C,OSR1,RDH10,TGFBR1,BMP4,WNT5A,CUL7,BMP2,FGFR2,ADAM15,SOX11,RTN4,GBX2,SEMA3A,SEMA3B,ACVR1,CTNNB1,MSX2,HIF1A,SEMA3D,GDNF,EDNRB,HGF,CORO1C,SEMA3E
GO:0033619	membrane protein proteolysis	GO_MEMBRANE_PROTEIN_PROTEOLYSIS	0.361098021192179	1.27301306809972	0.137846209912536	0.549751590717533	33	PARL,CTSH,ADAM19,NCSTN,MBTPS1,NAPSA,PSENEN,P2RX7,NFKB1,ADAM10,RHBDD1,APH1A,PRKCQ,PSEN2,TMPRSS6,SPPL3
GO:0035855	megakaryocyte development	GO_MEGAKARYOCYTE_DEVELOPMENT	0.449343989556448	1.31295394105747	0.138407211225723	0.551335707675482	16	EP300,FLI1,C6orf25,MED1,SRF,ABI1,VPS33B,TAL1,MEIS1
GO:0051127	positive regulation of actin nucleation	GO_POSITIVE_REGULATION_OF_ACTIN_NUCLEATION	-0.436916006560275	-1.31282265501392	0.138710305864017	0.551889940352579	16	WASF1,WHAMM,SCIN,WIPF2,TRIM27,NCKAP1,WIPF3
GO:0046467	membrane lipid biosynthetic process	GO_MEMBRANE_LIPID_BIOSYNTHETIC_PROCESS	-0.259034186996151	-1.19198686756001	0.139224230302164	0.553280707434576	103	GAL3ST1,P2RX1,ALDH3B1,DEGS2,PRKD1,PIGV,PIGW,B3GNT5,SGPP2,PIGX,ALDH3A2,SMPD2,ALOX12B,SGPL1,PLAUR,GAL3ST2,GAL3ST4,PIGU,CERS2,SGMS2,KDSR,ALDH3B2,ST3GAL5,PIGZ
GO:0005976	polysaccharide metabolic process	GO_POLYSACCHARIDE_METABOLIC_PROCESS	0.290727944404247	1.21920783779247	0.139756028967166	0.553846153846154	75	CHIT1,AKT2,PYGB,PYGM,PGM5,CALM3,NDST1,PHKG1,GYS1,GSK3B,PFKM,GCK,HAS3,STK40,PPP1R3A,CALM1,PPP1R3B,PHKA2,PHKB,GYG1,PPP1CB,PPP1R3E,EPM2A,PRKAG3,PHKG2
GO:0016358	dendrite development	GO_DENDRITE_DEVELOPMENT	0.29033660744666	1.22047722076031	0.139831177719671	0.553846153846154	76	SHANK3,NRP1,GRIN3A,PREX2,DLG4,STRN,HDAC2,APP,VLDLR,SHANK1,RERE,PTEN,DCLK1
GO:0035588	g protein coupled purinergic receptor signaling pathway	GO_G_PROTEIN_COUPLED_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY	0.440309932220696	1.30803385223892	0.13986013986014	0.553846153846154	17	P2RY1,P2RY2,ADCY5,P2RY13,ADORA2B,PTAFR
GO:0032355	response to estradiol	GO_RESPONSE_TO_ESTRADIOL	-0.242301400787964	-1.17149954441539	0.140087846293524	0.55409599368273	140	ASS1,SLC34A1,C3,SSTR3,RARA,AREG,RBBP8,BMP4,WNT5A,SSTR2,CTGF,FOXA1,CALR,ANXA1,SOCS1,TACR1,MBD3,CTNNB1,CAT,STAT3,EGFR,MSX2,HIF1A,CASP3,LEP,HTR5A,NQO1,CCNA2,HMBS,CYP1A2,MYOD1,ZNF703,AHR,EEF2,F3,SOCS3,PAWR,IL10,PTGFR,WNT7A,ARNT2,NTS,NRIP1,CCDC62
GO:0051047	positive regulation of secretion	GO_POSITIVE_REGULATION_OF_SECRETION	-0.205165553173238	-1.11831262672196	0.140571554672846	0.555356635010327	354	ATP13A2,CFTR,NMU,RBP4,SMPD3,EZR,CCL3,GSDMD,TNFSF11,CCL19,NKX6-1,NLGN1,NMB,NPR1,AQP1,WNT5A,RAB27B,RETN,GATA3,SDC1,HLA-DRB5,NPY2R,C1QTNF1,SOX11,IQCF1,SNCA,TACR1,SLC18A1,XBP1,ALOX12B,PYCARD,LPL,SERP1,HIF1A,SNF8,SAA1,HCAR2,LEP,SEC24A,IL17RC,CHRNB2,CDK5,VAMP8,CACNA1I,NNAT,S100A9,CLEC5A,UNC13B,SCIN,IL17F,GDNF,EDNRB,KCNB1,C5,CLEC4E,CYP4F2,SLC30A8,NLRP3,IL5,NLRP12,CD34,KCNN4,STXBP1,STXBP5L,IFNAR1,ADCYAP1,ADAM9,GAL,F2R,CARTPT,ABAT,TMF1,MIF,EDN1,VTCN1,FCER1A,HLA-DRB1,IL17RB,MAPK11,PTGER4,PLB1,INHBA,ABL1,CD276,SYT1,FOXL2,IL4R,GOLPH3L,IL10
GO:0071498	cellular response to fluid shear stress	GO_CELLULAR_RESPONSE_TO_FLUID_SHEAR_STRESS	-0.419011367801726	-1.30122047205051	0.141033698125474	0.555713394206135	18	ASS1,KLF4,XBP1,HDAC3,PKD2,NFE2L2,MAP2K5,PTK2B,KLF2
GO:0002761	regulation of myeloid leukocyte differentiation	GO_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	-0.262152778174773	-1.19358184724694	0.141119279108371	0.555713394206135	97	PRKCA,CCL3,TNFSF11,RARA,PTPN2,HOXA7,CEBPB,FSHR,CTNNB1,TJP2,RIPK1,CSF1,IL20,IRF7,TFE3,ADIPOQ,SLC9B2,ZNF675,CLDN18,IL5,CARTPT,MAFB,FSHB,MYC,TESC,RASSF2,TRIB1,INHBA
GO:0033688	regulation of osteoblast proliferation	GO_REGULATION_OF_OSTEOBLAST_PROLIFERATION	-0.393245688593143	-1.28923679069543	0.141231314700926	0.555713394206135	22	BMP2,FGFR2,CYR61,HPSE,RHOA,PLXNB1,ABL1,BCL2,LTF
GO:0003007	heart morphogenesis	GO_HEART_MORPHOGENESIS	0.238697252936157	1.16438872932942	0.141517842405836	0.555713394206135	199	UBE4B,TBX2,DLC1,DVL2,NPY1R,NDRG4,C2CD3,MEGF8,RYR2,HAND2,MYBPC3,YAP1,BMP10,IFT172,EYA1,XIRP2,GJA1,CHD7,SUFU,SMARCD3,CAV3,TCAP,PKP2,TTN,TNNI3,MYH7,EGLN1,SIX1,SHH,DLL4,ERG,MYL2,GJA5,MTOR,ZMIZ1,TBX5,TBX20,S1PR1,NKX2-5,TEK,NPY5R,FAT4,FHL2,RXRA,SOX17,VEGFA,ATF2,PTCH1,ENG,TNNT2,SOX9,SETDB2,LEMD2,WNT11,HEY2,MKKS,SMAD7,SMAD3,FGF8,PLXND1,PROX1,TBX3,MSX1,MED1,NOTO,TH,MEF2C,SRF,TWIST1,DSP,PTCD2,TGFBR3,OLFM1,SEC24B,SMO,FOXC2,RARB
GO:0000272	polysaccharide catabolic process	GO_POLYSACCHARIDE_CATABOLIC_PROCESS	0.40031621096869	1.29071900789396	0.141636971455861	0.555713394206135	23	CHIT1,PYGB,PYGM,CALM3,PHKG1,PFKM,CALM1,PHKA2,PHKB,GYG1
GO:0003143	embryonic heart tube morphogenesis	GO_EMBRYONIC_HEART_TUBE_MORPHOGENESIS	0.308418760184009	1.23427687832763	0.14165243381725	0.555713394206135	59	TBX2,NDRG4,C2CD3,MEGF8,RYR2,HAND2,YAP1,IFT172,GJA1,SUFU,SHH,TBX20,NKX2-5,SOX17,ENG,SETDB2,MKKS,SMAD3,FGF8,TBX3,NOTO,MEF2C,SRF
NA	patterning of blood vessels	GO_PATTERNING_OF_BLOOD_VESSELS	0.363282619578859	1.27183452629662	0.142521534847298	0.558472044582079	32	LRP5,NRP1,TGFBR2,NFATC4,SHH,DLL4,TBX20,VEGFA,ENG,SPI1,FGF8,PLXND1,COL4A1,BAK1,SRF,STK4,FOXC2
GO:0032103	positive regulation of response to external stimulus	GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	-0.211940279354039	-1.12697871850742	0.14317637669593	0.560385679021511	282	PLA2G2A,PRKCA,C3,IL16,SCG2,CNR1,CCL3,TNFSF11,CCL19,MAPK13,IL17B,KDR,IL18,SNW1,FFAR3,PRKD1,WNT5A,MET,OSMR,CCR6,KLK7,TNFSF14,LY96,ANO6,LPAR1,RPS19,OPRM1,CALR,AGTR1,CXCL1,FGF18,F7,S100A12,IL6ST,CCL21,RIPK2,CSF1,SH3GLB1,LPL,RAB3GAP2,HIF1A,F2,ARTN,TNFRSF1A,FABP4,IL17RC,TLR10,VAMP8,C5AR1,S100A9,RARRES2,IL17F,KLK5,NLRP12,TLR9,CMKLR1,DCN,KIAA1324,THBS1,NOD1
GO:0014823	response to activity	GO_RESPONSE_TO_ACTIVITY	0.30235916620885	1.22663956832533	0.143588018694236	0.561344100957954	63	AGT,PPARD,TPH2,AKT2,RYR2,CAPN3,UQCRC1,GSK3B,PRKAA2,HADH,SRL,ALAD,ESR2,ADSSL1,CREB1,CDK1,PLAU
GO:0071709	membrane assembly	GO_MEMBRANE_ASSEMBLY	0.389523451273923	1.28242911489446	0.144390816832137	0.563235130716361	25	NLGN3,IL1RAPL1,NRXN1,CDH2,PACSIN2,CAV3,PTEN,ANK3,NLGN4X,FLOT1,NLGN2,EMP2,SPTBN1
GO:0043462	regulation of atpase activity	GO_REGULATION_OF_ATPASE_ACTIVITY	0.310590166433008	1.23420996510521	0.144406392694064	0.563235130716361	57	UHRF1,SNRNP70,ATPIF1,ADRB2,RYR2,MYBPC3,OXA1L,PPIF,PLN,TNNI3,TPM2,METTL21A,AHSA2,TNNT2,SUMO1,TNNT3,PFN2,DNAJC9,RAB3A,CHTOP,MYL4,ATP1B2
GO:1901989	positive regulation of cell cycle phase transition	GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.301249511115507	1.22617354729771	0.144614297075197	0.56339319902212	64	CUL4A,DDX3X,NPM1,APP,CREBBP,CCND1,GOLGA2,SMARCD3,PTEN,GORASP1,FAM83D,KCNA5,ANAPC11,ANKRD17,DLGAP5,RDX,ESPL1,CYP1A1,PPP1R1C,PHOX2B,NSMCE2,SIN3A,PLK1
GO:0031570	dna integrity checkpoint	GO_DNA_INTEGRITY_CHECKPOINT	0.255490391647127	1.18316797424232	0.145119848541195	0.564709144727933	136	BRSK1,RPA4,PPP2R5C,FBXO6,FOXN3,TAOK2,MAPKAPK2,NPM1,ZAK,CCND1,TAOK3,PLAGL1,FZR1,CDK5RAP3,TFDP2,CNOT6L,CNOT4,DGKZ,EP300,FBXO31,CDKN1B,CDK1,ATF2,USP28,PRPF19,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,CLSPN,GIGYF2,FOXO4,PRKDC,MRE11A,CNOT1,TIPIN,BABAM1
GO:1902175	regulation of oxidative stress induced intrinsic apoptotic signaling pathway	GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.379819957690729	1.27487033964473	0.145394941669872	0.565126297529778	27	TRAP1,FBXW7,PINK1,SOD2,PARK7,SOD1,HSPB1,SFPQ,NME5,VNN1,HSPH1
GO:0043114	regulation of vascular permeability	GO_REGULATION_OF_VASCULAR_PERMEABILITY	0.372051162652616	1.27157332638868	0.146056546260974	0.566576126771668	29	AMOT,ABR,VEGFB,ARHGAP35,UCN,PDE2A,TEK,CTNNBIP1,VEGFA,MYLK3
GO:0060602	branch elongation of an epithelium	GO_BRANCH_ELONGATION_OF_AN_EPITHELIUM	-0.424460875548007	-1.29813049007269	0.146104598347536	0.566576126771668	17	RDH10,AREG,BMP4,WNT5A,FGFR2
GO:0021700	developmental maturation	GO_DEVELOPMENTAL_MATURATION	-0.229058679612656	-1.15008821641312	0.146911182302046	0.568054694879687	181	CFTR,CCL19,NKX6-1,IRX5,EPB42,AGRN,BMP2,RYR1,ANO6,GATA3,THBS3,CEND1,FOXA1,IQCF1,SPTBN4,XBP1,RAB38,INSL3,REC8,CTNNB1,CCL21,CEBPA,SLC17A7,CDKN1A,TMEM79,HIF1A,L3MBTL3,TYMS,LEP,CCNB1,KIAA0196,PPARG,CBFB,FBXO5,SEZ6,PICK1,STXBP1,NRCAM,POU2F2,RHOA,NTN4,BHLHA15,FOXO3,FAM20C,SNAPIN,PLXNB1,PABPC1L,RET,HOXB13,FEV,RPS6KA2,BLOC1S3,PICALM,BFSP1,PHOSPHO1,PALM,AP1M1,NR4A2,PTK2B
GO:0070169	positive regulation of biomineral tissue development	GO_POSITIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT	-0.336225717614935	-1.24973969735246	0.146912672415714	0.568054694879687	36	WNT6,OSR1,BMP4,BMP2,ANO6,ACVR1,WNT10B,BMPR1B
GO:0009185	ribonucleoside diphosphate metabolic process	GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS	0.305871863206665	1.22792014740938	0.147048370473043	0.568054694879687	60	BAD,DLG4,OGDHL,ENTPD4,AK1,PGAM2,PGAM1,OGDH,DLG2,DHTKD1,AK4,PFKM,GCK,PFKFB4,PFKP,ALDOC,ALDOA,HK3,ENO2,GALK1
GO:0060993	kidney morphogenesis	GO_KIDNEY_MORPHOGENESIS	-0.271809157088786	-1.19620621529783	0.147160931056176	0.568054694879687	80	GCNT3,WNT6,PAX8,OSR1,WT1,BMP4,BMP2,NPNT,GATA3,GCNT1,CTNNB1,WNT7B,IRX1,GDNF,WNT9B,PKD2,MYC,DLG1,ADAMTS16,IRX2,FRAS1,BCL2,FGF2
GO:0072009	nephron epithelium development	GO_NEPHRON_EPITHELIUM_DEVELOPMENT	-0.264854609448625	-1.19016334157	0.147702897013413	0.568896555254133	90	WNT6,PAX8,OSR1,WT1,BMP4,BMP2,NPNT,GATA3,UMOD,POU3F3,CTNNB1,NPHS1,WNT7B,IRX1,MAGI2,GDNF,CD34,WNT9B,PKD2,BASP1,MYC,DLG1,ADAMTS16,IRX2,PODXL,BCL2,FGF2
GO:0008654	phospholipid biosynthetic process	GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS	0.232997006728836	1.15354408816707	0.147825094561106	0.568896555254133	223	PIK3C2B,IDI2,CHAT,PIK3R1,MTMR1,PPARD,LPIN1,DDHD2,PCYT1A,FITM2,TAZ,CHPT1,FADS1,PLD1,LCAT,PLA2G5,SERINC5,INPP5J,PIP5K1B,ARF1,INPPL1,LPCAT4,AGPAT3,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,MVD,INPP5D,PIK3C3,FITM1,PIP4K2C,IRS1,GGPS1,PIKFYVE,PI4K2A,GPAA1,PIP4K2B,FGFR1,AGPAT1,CDS2,MBOAT2,PCYT1B,PIK3R5,PIK3C2G,DGKE,MPPE1,PLD6,PIGM,LCLAT1,IDI1,PIP5K1C,GAB1,SGMS1,FGF6,VAC14,FGF8,MTMR14,SLC27A1,SACM1L,INPP5F,CHKA,TAMM41,MBOAT1,DPM2,PLA2G4D,PIGS,MTMR2,PCYT2,PIK3R6,CDIPT,ISYNA1,PIK3R2,PIK3CB
GO:2000514	regulation of cd4 positive alpha beta t cell activation	GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	-0.330478568527681	-1.24308352950197	0.147886062343246	0.568896555254133	38	CD55,CCL19,RARA,GATA3,IL27,ANXA1,RIPK2,IRF4
GO:0048732	gland development	GO_GLAND_DEVELOPMENT	-0.203055500902231	-1.11204587716497	0.148124514482299	0.56916337414089	369	ASS1,SEMA3C,TPH1,SOX3,EZR,PTPN3,TNFSF11,PAX8,KDM1A,LIPC,RARA,WT1,ALDOB,TGFBR1,ID4,AREG,SEC63,BMP4,WNT5A,IGSF3,HOXA3,BMP2,FGF7,LSR,DUOX2,GATA3,CEBPB,FGFR2,TG,MAP2K2,FOXF1,FOXA1,TSPO,CRIP1,SEMA3A,ANXA1,PRMT5,POU3F2,COBL,XBP1,ATP2B2,EDAR,CTNNB1,SULF2,CP,CEBPA,CSF1,SLC6A3,EGFR,MSX2,WNT7B,HIF1A,CPS1,RIPK3,CEBPG,ZIC3,HK2,ORAI1,RAPGEF3,NKX2-3,RAG1,ZBTB1,KRT76,ONECUT1,FAS,CDH1,HGF,FASN,RPS6KA1,CAPN1,ADCYAP1,BSX,EPHA2,CACNB4,MSN,ZNF703,ATP7B,INSM1,PKD2,GSX1,MAFB,NODAL,AFP,LMO4,PYGO2,CDC42
GO:0034976	response to endoplasmic reticulum stress	GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS	-0.22186954576279	-1.13929810997898	0.148653851089495	0.570546023679864	213	BBC3,UFL1,KDELR3,SEC63,CUL7,PDIA4,CEBPB,ALOX15,PDIA6,CREB3L1,AUP1,CHAC1,CALR,SEC61G,SERP2,ATF3,DDX11,SSR1,XBP1,ATP6V0D1,TOR1A,IGFBP1,UFC1,BRSK2,TBL2,SERP1,ERP44,EIF2AK3,ATF6,PDIA5,MBTPS2,ERLEC1,EIF2AK4,JKAMP,FBXO2,TTC23L,RNF185,THBS1,BAX,CREB3L3,DNAJC3,HDGF,DNAJB9,HM13,UBXN4,BHLHA15,SEC61A1,SEC31A,DNAJC10,NFE2L2,AMFR,UFM1,GET4,UBE2J2,THBS4,EEF2,RNF139,ZBTB17,DERL2,UBQLN1,ASNA1
NA	regulation of pri mirna transcription from rna polymerase ii promoter	GO_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER	0.443708610822549	1.29648773055952	0.148982436576526	0.570647012267511	16	PPARD,PDGFB,PPARA,NFIB,NFATC4,SPI1,SRF
GO:0006090	pyruvate metabolic process	GO_PYRUVATE_METABOLIC_PROCESS	0.303695570338675	1.22384674961743	0.149176754160537	0.570647012267511	61	DLAT,OGDHL,HAGH,DLD,PGAM2,PGAM1,OGDH,DHTKD1,PDHA1,PFKM,GCK,PFKFB4,PDHX,PFKP,ALDOC,PDHB,ALDOA,HK3,ENO2,GALK1,HOGA1
GO:0002791	regulation of peptide secretion	GO_REGULATION_OF_PEPTIDE_SECRETION	0.237121730035223	1.15761666518251	0.149188761377127	0.570647012267511	200	LRP5,GNAS,BAD,PPARD,TRPM4,BMP8A,SYT9,ITPR1,NRXN1,PDE8B,RAPGEF4,TIAM1,CACNA2D2,DRD2,CDK16,GHSR,ADRA2C,GIPR,STX1A,GJA1,GLP1R,HMGCR,CHD7,SYT7,PDE4C,JAK2,REST,SLC25A4,SIRT4,UCN,PFKM,IRS1,ADCY5,GCK,ANO1,HADH,STX4,GLUD1,CACNA1C,KCNA5,TNF,GABBR1
GO:0030073	insulin secretion	GO_INSULIN_SECRETION	-0.333041573836012	-1.24564468411015	0.149603484865408	0.571583802561821	37	ILDR2,ANXA1,STXBP3,PCLO,EIF2AK3,LEP,SLC18A2,SMAD2,GPR119,SLC30A8,GAL,ACVR2B,CYB5R4
GO:0001704	formation of primary germ layer	GO_FORMATION_OF_PRIMARY_GERM_LAYER	-0.254037078474189	-1.17805095210835	0.149989209409395	0.57240779917463	108	VTN,TBX6,ITGA3,BMP4,WNT5A,LAMA3,T,FGFR2,FOXF1,CRB2,LEO1,ACVR1,KLF4,CTNNB1,NR4A3,SMAD2,COL7A1,ETV2,EPHA2,NODAL,DUSP2,LAMB3,COL12A1,INHBA,AXIN1,MMP14,ITGB4,WNT3,COL11A1,NOG,GATA6,TWSG1,DUSP1,HSBP1,TRIM15,FOXC1,MMP9,EOMES,MIXL1,FN1,WNT3A,COL6A1,EXT2,BMP7
GO:0050821	protein stabilization	GO_PROTEIN_STABILIZATION	0.260857492307149	1.18450944923086	0.150557936993944	0.573927537850076	119	PIK3R1,ZSWIM7,FBXW7,ANK2,TMEM88,PIN1,TSC1,HSPD1,PINK1,USP13,USP2,BAG3,PTEN,SEL1L,GTPBP4,DNAJA3,EP300,TCP1,AAK1,CREB1,PARK7,SOX17,CCT3,BAG6,SMAD7,SMAD3,SUMO1,CDC37L1,PFN2,UBE2B,CSN3,RASSF1,MSX1,CCT7,TSPAN1,CCT4,ATP1B2,MT3,SYVN1,STK4,SMO,MDM4,PPARGC1A,WFS1,HSP90AB1,HCFC1,PEX19,CDKN2A,USP19,COG7,FKBPL,PEX6,CCT8
GO:0043299	leukocyte degranulation	GO_LEUKOCYTE_DEGRANULATION	-0.356594032279655	-1.25655137205504	0.151498396549818	0.576859279170459	29	MRGPRX2,CCL3,ANXA3,NR4A3,STXBP3,SNAP23,VAMP8,LAT
GO:0010959	regulation of metal ion transport	GO_REGULATION_OF_METAL_ION_TRANSPORT	0.221507447938297	1.13448092225864	0.152172526000128	0.578391185561084	299	AGT,PRKACA,CACNA2D4,OPRL1,PDGFB,ANK2,LPAR3,DRD4,VIP,ADRB2,TRPV2,DMPK,SCN5A,CALM3,CAMK2A,CACNA2D1,RYR2,S100A1,KIF5B,NEDD4L,CAPN3,XCL1,ATP1A2,LGALS3,DRD2,HRC,OPRK1,RNF207,KCNJ2,VAMP2,PCSK9,WNK2,ADCYAP1R1,CXCL11,FXYD3,GJA1,ARF1,AKAP6,CAV3,DMD,CXCR3,UCN,PKP2,FXYD1,PLN,STC2,GCK,PLCB4,SLC8A1,KCNH2,CALM1,AHNAK,CAMK2G,MYLK,GLRX,CACNA1C,TSPAN13,HAMP,KCNA5,NKX2-5,KCNRG,SEMG1,CAMK2B,CNTN1,HOMER1,CACNA1B,P2RX7,CYBA,ANK3,KCNIP2,CXCL9,PLCG1,ZP3,SLC30A1,GNAO1,HTT,FGF12,TRDN,SUMO1,JPH2,LILRB1,CNKSR3,PRKCE,SNTA1,COMMD1,EGF
GO:0033014	tetrapyrrole biosynthetic process	GO_TETRAPYRROLE_BIOSYNTHETIC_PROCESS	0.377343354406364	1.26655759038979	0.152244382176803	0.578391185561084	27	COX15,ATPIF1,MMAA,COX10,MMACHC,ALAD,FXN,NFE2L1,SLC25A38,RSAD1,FECH,SLC25A39,MMAB,SUCLA2,PPOX,CPOX
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY_INVOLVED_IN_APOPTOTIC_PROCESS	0.41301885894666	1.28205391240042	0.152479644707624	0.578631887357229	20	RHOT2,BAD,MOAP1,CAMK2A,ATF2,BID,BMF,BNIP3
GO:0043268	positive regulation of potassium ion transport	GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT	0.347402832867345	1.24953398960233	0.152834467120181	0.579325243610958	36	ANK2,ADRB2,KIF5B,OPRK1,RNF207,KCNJ2,AKAP6,KCNH2
GO:0009950	dorsal ventral axis specification	GO_DORSAL_VENTRAL_AXIS_SPECIFICATION	0.412814495909377	1.28141954807099	0.153034789045152	0.579432058409427	20	LRP5,CXXC4,LRP6,RGS20,PAX6,MDFI,EGF,VAX2,RGS19,LRP5L,SENP2,SMAD6
GO:0021915	neural tube development	GO_NEURAL_TUBE_DEVELOPMENT	-0.238815162636861	-1.15865581478534	0.153694920252636	0.580616934225854	143	PAX7,SEMA3C,TRAF3IP1,RARA,SPINT1,IFT57,BMP4,WNT5A,SFRP2,T,PTK7,GRHL2,TMED2,FOXA1,SOX11,MTHFD1L,GBX2,PLXNB2,COBL,PLXNA2,WDR19,HIF1A,ST14,FZD3,STK3,IFT52,ARL13B,EPHA2,RALA,TULP3,PKD2,SALL4,NODAL,LMO4,STIL
GO:0050900	leukocyte migration	GO_LEUKOCYTE_MIGRATION	-0.216109838813234	-1.12825918074998	0.15417436324375	0.580616934225854	242	MMP1,IL16,SCG2,CCL3,ITGA3,TNFSF11,CCL19,ARHGEF5,IRAK4,PROCR,CD177,CCR6,ANO6,ANGPT1,KRAS,GATA3,GCNT1,RPS19,ANXA1,UMOD,PODXL2,FUT7,S100A12,SLC7A10,CCL21,SLC7A8,ANGPT4,F2,ARTN,SAA1,LEP,IL17RC,MAG,GRB7,C5AR1,S100A9,NKX2-3,SLC16A1,SELPLG,EDNRB,PROS1,NLRP12,CD34,MSN,F11R,CCL4,MIF,EDN1,CDC42,SPNS2,SLC7A9,SLC3A2,CCL18,ELANE,RET,PODXL,ATP1B1,OLR1,PF4,SLC16A8,IL10,THBD,SLC7A11,RAC1,HRAS,PDE4B,ZAP70
GO:0072171	mesonephric tubule morphogenesis	GO_MESONEPHRIC_TUBULE_MORPHOGENESIS	-0.30125863743302	-1.2162315802364	0.154257367431536	0.580616934225854	52	WNT6,PAX8,OSR1,WT1,BMP4,BMP2,NPNT,GATA3,CTNNB1,GDNF,WNT9B,PKD2,MYC,DLG1,ADAMTS16,BCL2,FGF2,NOG
GO:0045851	ph reduction	GO_PH_REDUCTION	-0.338977849618313	-1.24248655185277	0.154333052014392	0.580616934225854	34	ATP6V1C2,ATP6V1B1,RAB38,ATP6V0D1,ATP6V1H,SLC17A7,ATP6V1A,CLN3,TTPA
GO:2000398	regulation of thymocyte aggregation	GO_REGULATION_OF_THYMOCYTE_AGGREGATION	0.390159526663116	1.27134573067024	0.154339594897622	0.580616934225854	24	ZEB1,GLI2,ZC3H8,SHH,ADA,SOD1,FOXJ1,FOXN1,VNN1,KIAA0922,NFKBID,FOXP3,CDKN2A,RASGRP1
GO:0001837	epithelial to mesenchymal transition	GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	-0.298610973869138	-1.2155481304318	0.154382696414777	0.580616934225854	54	TGFBR1,WNT5A,CUL7,BMP2,FGFR2,ADAM15,RTN4,CTNNB1,MSX2,HIF1A
GO:0030900	forebrain development	GO_FOREBRAIN_DEVELOPMENT	-0.20455331152517	-1.11111289087608	0.154787656416856	0.581490236048144	342	CCDC85C,HAP1,TYRO3,LRP2,SOX3,SSTR3,PHLPP2,DLX1,KDM1A,ANXA3,RARA,CDON,GDPD5,AQP1,ID4,BMP4,SSTR4,WNT5A,BMP2,SSTR2,WNT2B,DUOX2,KRAS,RFX4,GART,FGFR2,LPAR1,RTN4,GBX2,SEMA3A,FUT10,LHX5,SLC38A2,POU3F2,NRGN,OTX2,OTX1,POU3F3,CTNNB1,SLIT3,GNG12,FEZF1,NR4A3,SLC6A3,UBA6,EGFR,WNT7B,HIF1A,ROBO2,LRP8,EMX1,CASP3,CHRNB2,CDK5,HTR5A,FGF13,EXT1,LMX1A,FAS,CDH1,PCM1,KCNA1,SLC8A3,ARL13B,ADCYAP1,BAX,DOCK7
GO:0000375	rna splicing via transesterification reactions	GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS	0.227882821299976	1.14145468843363	0.155600279161865	0.583740570206204	247	TFIP11,SF3A2,RALY,METTL3,DGCR14,SNRNP35,SNRNP70,NCBP1,HNRNPM,PRMT7,PRPF6,NOVA2,SNRNP200,SPEN,PRPF3,DHX8,PCBP2,RAVER2,SNRPA,SF3B4,RBM17,SNRPN,CELF1,SCAF11,CLP1,DDX39B,LSM5,SRSF4,PDCD7,PRPF39,HNRNPH3,CPSF1,LUC7L,SFSWAP,POLR2I,SETX,CTNNBL1,LSM4,NCBP2,SRRT,XAB2,SMN1,PRPF31,HNRNPA2B1,RNPS1,AQR,SRSF1,SNRPC,PRPF19,SFPQ,SF3B3,U2AF1L4,CD2BP2,HTATSF1,SF1,LSM6,YBX1,SRRM2,DHX38,DDX20,GTF2F2,RBM5,POLR2C,RBM8A,SMNDC1,PQBP1,DDX23,WBP11,PSPC1,FUS,PRPF4B,WDR77,PRPF8,MPHOSPH10,RBM22,SART3,LSM1,UBL5,POLR2G,HNRNPU,PCBP1,CSTF3,RNPC3,SRSF12,SKIV2L2,POLR2L,DDX46,PCF11,GEMIN2
GO:2000649	regulation of sodium ion transmembrane transporter activity	GO_REGULATION_OF_SODIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.351515072246275	1.24789162310207	0.155740686845169	0.583740570206204	34	AGT,DRD4,NEDD4L,ATP1A2,PCSK9,WNK2,FXYD3,CAV3,DMD,FXYD1,GLRX,ANK3,FGF12,PRKCE,UTRN,STOM
GO:0090382	phagosome maturation	GO_PHAGOSOME_MATURATION	-0.344467302076679	-1.24395555915943	0.155906943736001	0.583740570206204	32	ATP6V1C2,RAB31,ATP6V1B1,RAB38,ATP6V0D1,ATP6V1H
GO:0002089	lens morphogenesis in camera type eye	GO_LENS_MORPHOGENESIS_IN_CAMERA_TYPE_EYE	-0.418973735242768	-1.28134914568061	0.156616342951075	0.585577800574884	17	BMP4,SOX11,CTNNB1,BCAR3,EPHA2,SHROOM2,PITX3
GO:0001841	neural tube formation	GO_NEURAL_TUBE_FORMATION	-0.261182367824524	-1.18094184530159	0.15675535305366	0.585577800574884	93	RARA,SPINT1,IFT57,BMP4,WNT5A,SFRP2,T,PTK7,GRHL2,TMED2,SOX11,MTHFD1L,PLXNB2,COBL,HIF1A,ST14,FZD3,STK3,IFT52,RALA,TULP3,SALL4,NODAL,LMO4,STIL
GO:0042471	ear morphogenesis	GO_EAR_MORPHOGENESIS	-0.253328885587048	-1.17329140737597	0.156919541330524	0.585577800574884	107	RPL38,PAX8,NKX3-2,OSR1,PDZD7,WNT5A,MYO15A,ATP6V1B1,NEUROG1,GATA3,PTK7,FGFR2,GBX2,OTX1,ATP2B2,USH1G,NR4A3,WDR19,HMX3,FZD3,PRKRA
GO:0043500	muscle adaptation	GO_MUSCLE_ADAPTATION	0.367452936471645	1.25585779490441	0.157500866993995	0.587096255040739	29	CFLAR,HDAC4,KLF15,TCAP,CYBA,HEY2,PSMB9,INPP5F,TRIM63,MEF2C,PPARGC1A,RPS6KB1
GO:1904886	beta catenin destruction complex disassembly	GO_BETA_CATENIN_DESTRUCTION_COMPLEX_DISASSEMBLY	0.404546499297558	1.27326368607058	0.15770629164129	0.587154878967511	21	LRP5,LRP6,DVL2,GSK3B,WNT8B,APC,CSNK1A1
GO:0007224	smoothened signaling pathway	GO_SMOOTHENED_SIGNALING_PATHWAY	-0.280578281505515	-1.19621767845024	0.157922751151327	0.587154878967511	68	NKX6-1,CDON,IFT57,BMP4,BBS7,FOXF1,WNT10B,PTCHD1,WDR19,EVC2,BOC,TTC26,IFT52,C21orf2,IFT20,ARL13B,IQUB,TULP3,TMEM231,KIAA0586,STIL
GO:0042886	amide transport	GO_AMIDE_TRANSPORT	-0.263785676858256	-1.18077361822462	0.158354671239634	0.587154878967511	88	PDPN,SMPD3,UBE2Q1,ILDR2,AQP3,ANXA1,STXBP3,PCLO,EIF2AK3,LEP,SLC18A2,SMAD2,FOLR3,ABCA1,SLC38A1,GPR119,SLC30A8,AQP11,GAL,ACVR2B,CARTPT,CYB5R4,EDN1
GO:0010506	regulation of autophagy	GO_REGULATION_OF_AUTOPHAGY	0.229378369209694	1.14225126680113	0.158373983739837	0.587154878967511	234	LRSAM1,WDFY3,PARL,BAD,HERC1,FLCN,RRAGB,FBXW7,UBQLN4,ITPR1,ATG14,TP53INP2,SNRNP70,EEF1A2,RRAGD,ADRB2,ULK1,LRRK2,CALCOCO2,TSC1,TPCN1,RAB12,GOLGA2,PINK1,KAT8,USP13,CAPNS1,RAB1B,PRKAA2,RAB3GAP1,PIP4K2C,DAPK2,ATP6V0E2,PIKFYVE,KAT2A,TLK2,TRIM13,PIP4K2B,RASIP1,SCOC,EP300,MEFV,MTOR,FOXO1,DAPK3,RNF152,PARK7,HDAC6,ATP6V0D2,VDAC1,USP36,HSPB1,TFEB,NPC1
GO:1903391	regulation of adherens junction organization	GO_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION	0.319919197867129	1.22683452990354	0.158388778996583	0.587154878967511	48	GPM6B,CLASP1,DLC1,ROCK2,TSC1,MACF1,PTEN,EPHA3,DAPK3,TEK,VEGFA,LDB1,RDX,SMAD3,LIMS1,BCAS3
GO:0048640	negative regulation of developmental growth	GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH	-0.268522667743853	-1.18484643099948	0.158604781210681	0.587308793790046	81	SEMA3F,SEMA3C,RBP4,BMP4,WNT5A,ULK2,SFRP2,WWC1,RTN4,SEMA3A,SEMA3B,TP73,MSTN,SEMA3D,STK3,CDK5,FGF13,SEMA3E,GAL,SEMA4B,SEMA4A,FSTL4,NKD1,MAPK11,KCNK2,WWC2,RNF6,WNT3,NOG,SEMA7A,SPP1
GO:0015914	phospholipid transport	GO_PHOSPHOLIPID_TRANSPORT	-0.301544475667225	-1.21232678394974	0.159070315331642	0.587979278602654	51	APOA2,APOC1,PITPNM3,MFSD2A,ATP8B3,ATP10B,ABCA7,TNFAIP8L3,ABCA1,ATP11C,PRELID1,ATP9A,KCNN4,ABCG1,TRIAP1,PITPNM1,OSBPL8
GO:0006984	er nucleus signaling pathway	GO_ER_NUCLEUS_SIGNALING_PATHWAY	-0.347252136740385	-1.24383334509207	0.159135211766791	0.587979278602654	31	CALR,ATF3,XBP1,IGFBP1,EIF2AK3,ATF6,SCAP,MBTPS2
GO:0071378	cellular response to growth hormone stimulus	GO_CELLULAR_RESPONSE_TO_GROWTH_HORMONE_STIMULUS	0.409779662148513	1.27199910536645	0.159492968171725	0.588024734900747	20	PIK3R1,STAT5B,JAK2,GH1,PXN,MAPK1,JAK3,PTK2,PRLR,MAPK3,PRL
GO:0002251	organ or tissue specific immune response	GO_ORGAN_OR_TISSUE_SPECIFIC_IMMUNE_RESPONSE	-0.360884404418053	-1.24941519713314	0.159496905218177	0.588024734900747	27	GCNT3,FFAR3,HIST1H2BE,HIST1H2BK,PIGR,RAB17,HIST1H2BF,FAU,CAMP,LTF
NA	multi organism behavior	GO_MULTI_ORGANISM_BEHAVIOR	0.289637498215626	1.20242751246823	0.15983014413081	0.588608605190708	71	SHANK3,NLGN3,NRXN1,DLG4,DRD4,APP,SHANK1,HAND2,VPS13A,PTEN,UCN,CLN8,DACH1,MTOR,CNTFR,MKKS,CRHBP,NCOA1,UBR3,NLGN4X,DNAJC9,NHLH2,TH,PPP1R1B,EN1,OXT,MTNR1A,PPP3CB,PEX13,GRN,DRD3,NCOA2
GO:2001242	regulation of intrinsic apoptotic signaling pathway	GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	-0.24319080019837	-1.15885240277417	0.160088843328208	0.58891699086639	128	NOC2L,BBC3,MAPK8IP1,TAF9B,KDM1A,SFRP2,PTPN2,MUC1,CREB3L1,SKIL,TXNDC12,XBP1,FIGNL1,NONO,DFNA5,PYCARD,BCAP31,HIF1A,EIF2AK3,RRM2B,PLAUR,RIPK3,TPT1,PRKRA,MAGEA3,RPS3,S100A9,BDKRB2
GO:0006513	protein monoubiquitination	GO_PROTEIN_MONOUBIQUITINATION	0.317627389839004	1.22336201734711	0.161024719101124	0.591041724746771	49	UHRF1,UBE4B,UBE2O,RNF40,PAF1,KDM2B,NEDD4L,UBE2T,HUWE1
GO:0060348	bone development	GO_BONE_DEVELOPMENT	-0.235157090118389	-1.14996831962408	0.16103664869677	0.591041724746771	151	MATN1,PPIB,NAB2,SULF1,RARA,CYP26B1,BMP4,SFRP2,BMP2,RYR1,ALPL,T,ANO6,THBS3,SERPINH1,FGFR2,PAPPA2,COMP,ANXA2,PAPSS2,FGF18,BMPR1B,SULF2,MSX2,FGF4,LEP,WHSC1,SPARC
GO:0071636	positive regulation of transforming growth factor beta production	GO_POSITIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION	0.437909882801264	1.27954422405756	0.16119319765821	0.591041724746771	16	SERPINF2,XCL1,CX3CL1,CREB1,ATF2,WNT11,SMAD3
GO:1903318	negative regulation of protein maturation	GO_NEGATIVE_REGULATION_OF_PROTEIN_MATURATION	-0.336243543632252	-1.23246424974613	0.161773197707991	0.592522941768332	34	CD55,C4BPA,GAS1,SERPING1,CHAC1,C4BPB,MASP1,MAGEA3,THBS1,TMEM59,MDM2
GO:0048701	embryonic cranial skeleton morphogenesis	GO_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS	-0.309093868649734	-1.21544014064082	0.162008024886164	0.592657804384189	46	IRX5,RDH10,TGFBR1,BMP4,GRHL2,FGFR2,MTHFD1L,CTNNB1,WDR19,SMAD2,SPEF2,WNT9B,TULP3,NODAL,SLC39A1
GO:0009954	proximal distal pattern formation	GO_PROXIMAL_DISTAL_PATTERN_FORMATION	-0.359866117390089	-1.24588979323038	0.162162162162162	0.592657804384189	27	DLX1,OSR1,CYP26B1,HOXC10,CTNNB1,IRX1,NODAL,IRX2
GO:0001706	endoderm formation	GO_ENDODERM_FORMATION	-0.30219980855773	-1.21031728000707	0.162437923250564	0.593021745836659	50	VTN,LAMA3,LEO1,CTNNB1,SMAD2,COL7A1,NODAL,DUSP2,LAMB3,COL12A1,INHBA,MMP14,COL11A1,NOG,GATA6,DUSP1,HSBP1,MMP9,EOMES,MIXL1,FN1,COL6A1,LAMB1
GO:0048146	positive regulation of fibroblast proliferation	GO_POSITIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION	-0.302102147642096	-1.20992614576268	0.162641083521445	0.593120137739093	50	AQP1,WNT5A,S100A6,ANXA2,CDKN1A,EGFR,CCNB1,CCNA2,SIRT6,FOSL2,MIF,MYC,PDGFD,CDC6,JUN,GAS6,FGF10,PDGFC,PTPRZ1,FN1,BTC,IGF1
NA	positive regulation of sequence specific dna binding transcription factor activity	GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY	-0.219907619595889	-1.12922363686378	0.163488437748633	0.594157739148124	213	EDA2R,TCF3,TNFSF11,NKX6-1,KDM1A,ARHGEF5,ANXA3,PRKD1,WNT5A,NEUROG1,KRAS,PRKCI,FOXA1,ALK,TRAF5,RIPK4,BEX1,MID2,CARD14,IRAK1,WNT10B,CTNNB1,TRIM62,CAT,S100A12,PYCARD,RIPK2,RIPK1,CHUK,TRADD,LRP8,ZIC2,UBA52,RIPK3,MBTPS2,IRAK3,RHEBL1,STK3,CEBPG,TRIM38,RPS3,IKBKG,PPARG,S100A9
NA	potassium ion import	GO_POTASSIUM_ION_IMPORT	0.377173339218821	1.25418203903518	0.163497680558866	0.594157739148124	26	KCNJ3,ATP1A2,KCNJ2,KCNJ1,SLC12A6,KCNJ13,ATP1A3,ABCC9,ATP1B2,KCNJ14,KCNJ4,KCNJ15
GO:0019320	hexose catabolic process	GO_HEXOSE_CATABOLIC_PROCESS	0.321992984155156	1.22345903901722	0.163515456506111	0.594157739148124	46	LRP5,BAD,PGM5,PGAM2,PGAM1,FUT5,PFKM,GCK,PFKFB4,PFKP,ALDOC,FUT4,ALDOA,HK3,ENO2,GALK1
GO:0009067	aspartate family amino acid biosynthetic process	GO_ASPARTATE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS	0.396060758201251	1.2615423822954	0.163631676824216	0.594157739148124	22	THNSL1,MTR,THNSL2,GOT2,EIF2B4,GOT1,ASNS,PLOD1,ASNSD1,BHMT,MTRR,AASDHPPT,ENOPH1,BHMT2,MTHFD2L
GO:2001233	regulation of apoptotic signaling pathway	GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY	0.216831048348904	1.12338603615188	0.163980997774656	0.594784524255919	333	TRAP1,MADD,AGT,TRAF1,ELL3,DDX3X,PARL,BAD,TMC8,SIAH1,NRP1,RBCK1,FBXW7,CFLAR,ANKRD2,DYNLL2,BIRC6,ATPIF1,MOAP1,LRRK2,GZMB,YAP1,LGALS3,ARHGEF2,PPIF,SP100,PINK1,EYA1,CTSH,CTNNA1,NKX3-1,OSM,PLAGL2,FEM1B,MKL1,GSK3B,JAK2,PTEN,STRADB,VDAC2,FBXO18,DAPK2,AGTR2,NFATC4,NMT1,BCL2L14,CX3CL1,AR,RAF1,FGFR1,STX4,APOPT1,TNFRSF10B,TNFSF10,PPP3R1,PPP1R13B,G0S2,DAPK3,IL4,TNF,CSF2,SOD2,PARK7,MAL,TRIM32,TIMP3,SOD1,GRINA,HSPB1,TMEM102,FAF1,SFPQ,FAM162A,MAGED1,IVNS1ABP,NME5,HYAL2,FXN,HTT,SMAD3,FASLG,BID,PIAS4,NDUFA13,OPA1,MAPK8,PCGF2,MSX1,YWHAG,VNN1,BAK1,GCG,TP53BP2,ING5,HSPH1,RRN3,CTH,LTBR,CASP2,SYVN1,GFRAL,HRK,STK4,BMF,FGG,SIAH2
GO:0032368	regulation of lipid transport	GO_REGULATION_OF_LIPID_TRANSPORT	-0.261794001859538	-1.17450585593963	0.164750146972369	0.596614687778149	89	APOA2,APOC1,TNFSF11,LRAT,RETN,C1QTNF1,TSPO,AGTR1,ADIPOQ,LEP,ABCA7,PPARG,ABCA1,POMC,PLTP,NR1H3,PRELID1,CYP4F2,THBS1,GAL,ABCG1,TRIAP1,LRP1,TMF1,MIF,EDN1
GO:0046939	nucleotide phosphorylation	GO_NUCLEOTIDE_PHOSPHORYLATION	0.310245200783784	1.21520454556255	0.164861870555019	0.596614687778149	53	CMPK2,OGDHL,AK1,PGAM2,PGAM1,OGDH,DHTKD1,AK4,PFKM,GCK,PFKFB4,NME6,PFKP,ALDOC,ALDOA,HK3,ENO2,GALK1,NME5
GO:0006953	acute phase response	GO_ACUTE_PHASE_RESPONSE	-0.327929605055081	-1.22652485872631	0.165017312632637	0.596614687778149	37	ASS1,SERPINA3,HP,CEBPB,STAT3,HIF1A,F2,SAA1,ORM1,MBL2
GO:0072006	nephron development	GO_NEPHRON_DEVELOPMENT	-0.249923715101088	-1.16199181949719	0.165206929740135	0.596659362130143	110	WNT6,ITGA3,SULF1,PAX8,OSR1,WT1,BMP4,BMP2,NPNT,ANGPT1,GATA3,UMOD,POU3F3,CTNNB1,SULF2,NPHS1,WNT7B,IRX1,MAGI2,GDNF,CD34,WNT9B,PKD2,BASP1,MYC,DLG1,ADAMTS16,IRX2,PODXL,BCL2,FGF2
GO:0051646	mitochondrion localization	GO_MITOCHONDRION_LOCALIZATION	0.354499313587665	1.24108460540148	0.165504179490448	0.596730718659604	32	RHOT2,MARK2,MFN2,LRRK2,KAT2A,SLC4A5,HDAC6,MAP1S,OPA1,ATP2A1,NEFL,MAPT,LRPPRC,OGT,MAP1B,PLIN5,MSTO1
GO:0007205	protein kinase c activating g protein coupled receptor signaling pathway	GO_PROTEIN_KINASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	-0.344861428558571	-1.23526999229937	0.165581251107567	0.596730718659604	31	BDKRB1,DGKB,GAP43,HTR1B,PICK1,F2R,DGKA,LRP1,HCRT,EDN1
GO:0021756	striatum development	GO_STRIATUM_DEVELOPMENT	0.443896376980065	1.27552180189377	0.166229855573524	0.598116061509099	15	SHANK3,DRD2,OGDH,MKKS,RARB,BBS2
GO:0046131	pyrimidine ribonucleoside metabolic process	GO_PYRIMIDINE_RIBONUCLEOSIDE_METABOLIC_PROCESS	0.380531518447909	1.25282495006807	0.166321043842102	0.598116061509099	25	UPP2,ENTPD4,UCKL1,NME6,AICDA,NME5,APOBEC3H,CAD,DHODH,APOBEC1,UMPS
GO:0045581	negative regulation of t cell differentiation	GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION	0.360817883308844	1.24355110108968	0.166499461904675	0.598118664643689	30	CTLA4,HLX,ZC3H8,SHH,IRF1,DTX1,IL4,HMGB1,BCL6,FOXJ1,TNFSF4,JAK3,KIAA0922,NFKBID,FOXP3,CDKN2A,RC3H1
GO:0002709	regulation of t cell mediated immunity	GO_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY	0.312440545655493	1.21431975007575	0.166887464642486	0.598873353930287	51	TRPM4,RSAD2,XCL1,SPN,CEACAM1,HSPD1,HLA-B,PRKCZ,P2RX7,MALT1,ZP3,HMGB1,CLC,LILRB1,TNFSF4,HLA-E,IL12RB1,FOXP3,PPP3CB,STX7
GO:0006493	protein o linked glycosylation	GO_PROTEIN_O_LINKED_GLYCOSYLATION	-0.263112180963573	-1.17308847692876	0.167279885636615	0.598923150921012	86	GCNT3,MUC2,GALNT12,MUC7,MUC16,MUC5B,B3GNT6,B3GNT5,POGLUT1,MUC1,PGM3,GCNT1,MUC6,GALNT5,FKTN,ADAMTSL1,B4GALT5,GALNT10,GXYLT2,THBS1,MUC21,GALNT1,C1GALT1C1,ISPD
GO:0006820	anion transport	GO_ANION_TRANSPORT	-0.194156053928837	-1.0896927774533	0.167481132348264	0.598923150921012	476	SLC22A24,SLC1A6,PDPN,SLC26A9,CFTR,SLC34A1,CA12,SLC36A2,APOA2,APOC1,PLIN2,PITPNM3,SNAP25,NMB,CA9,EMB,AQP1,MFSD2A,SLC10A3,SLC22A4,BEST1,SLC1A1,ANO6,SLC7A3,SLC10A1,TG,SLC4A4,SLC17A5,GABRA4,TSPO,CLCNKB,ANO3,ANXA1,SLC6A17,SLC38A2,SLC22A31,ABCB11,SLC22A25,SLC25A6,SLC7A10,SLC17A2,P2RY4,SLC17A7,SLC7A8,SLC7A2,CLIC3,ATP8B3,SLC35A3,ATP10B,SLC22A20,PRAF2,LEP,PLA2G4F,GLRA4,ABCA7,SLCO5A1,CALHM1,SLC25A22,CLCA2,TNFAIP8L3,SLC1A4,PPARG,FOLR3,CA3,UNC13B,ABCA1,SERINC2,BDKRB2,SLC16A1,ARL6IP5,ATP11C,SLC38A1,PRELID1,SLC22A8,SLC13A5,AGXT,ATP9A,SLC38A8,SLCO1B3,KCNN4,STXBP1,CROT,FABP1,CA5A,CACNB4,SLC6A14,ABCG1,SLC27A4,TRIAP1,SLC22A17,SLC7A4,TTYH1,CLN3,SLC32A1,CYB5R4,SLC2A2,SLC37A1,SLCO2A1,PITPNM1,OSBPL8,SLC2A1,ANO7,SLC7A9,SLC3A2,LRRC8E,SLC23A2,CLIC1,SLC17A6,GABRA6,SLC38A11,SLC13A4,GRM2,SLC6A9,CLCN5,AQP9,PSEN1,SLC16A2,SLC20A1,GABRG2,ABCC4,SYT1,ASNA1,SLC16A8,GABRB2,SLC7A13,PLA2G4A,SLC16A4,SLC6A12,ACACA,SLC7A11,SH3BP4
GO:0061326	renal tubule development	GO_RENAL_TUBULE_DEVELOPMENT	-0.270754458000137	-1.18013409940555	0.167530626002464	0.598923150921012	76	WNT6,PAX8,OSR1,WT1,BMP4,BMP2,NPNT,GATA3,UMOD,POU3F3,CTNNB1,WNT7B,IRX1,GDNF,WNT9B,PKD2,MYC,DLG1,ADAMTS16,IRX2,BCL2,FGF2
GO:0060317	cardiac epithelial to mesenchymal transition	GO_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	-0.37692295937043	-1.25018698033534	0.167712906057946	0.598923150921012	23	TGFBR1,BMP2,ADAM15,RTN4,MSX2
GO:0002703	regulation of leukocyte mediated immunity	GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.247806331304675	1.15882096756794	0.16779100752184	0.598923150921012	146	TRPM4,RSAD2,UNC13D,STAT5B,CRTAM,UNG,XCL1,SPN,VAMP2,CEACAM1,HSPD1,ABR,CD300A,CD40,HLA-B,STX4,PRKCZ,CR1,CCR2,IL4,TNF,MICA,EXOSC3,P2RX7,SH2D1B,MALT1,ADORA2B,PTAFR,IL2,ZP3,HMGB1,BTK,SH2D1A,CLC,LILRB1,BCL6,FOXJ1,TNFSF4,TLR4,IL21,PAXIP1,PIK3R6,JAK3,AP1G1,NOS2,HLA-E,TAP1,SUSD4,IL12RB1,FOXP3,PPP3CB
GO:0006446	regulation of translational initiation	GO_REGULATION_OF_TRANSLATIONAL_INITIATION	0.286233269563692	1.19144436388189	0.169222102909853	0.602918815309164	72	METTL3,DDX3X,EIF2B5,NPM1,MKNK1,NCBP1,PAIP2B,KHDRBS1,PAIP2,YTHDF2,NCBP2,TNF,RXRA,HSPB1,EIF3J,EIF1B,IMPACT,EIF2B4,TPR,EIF4G1,EIF2AK1,EIF2S1,EIF3D
GO:0006006	glucose metabolic process	GO_GLUCOSE_METABOLIC_PROCESS	0.260030655883299	1.16998137835677	0.169268651356851	0.602918815309164	113	LRP5,BAD,PPARD,AKT2,DLAT,NPY1R,PGM5,PGAM2,PGAM1,SLC25A11,INPPL1,PDHA1,PFKM,GCK,MDH2,MDH1,WDTC1,PFKFB4,GOT2,OAS1,PFKP,TNF,ALDOC,PDHB,ALDOA,HK3,ENO2,SERPINA12,GOT1,CRTC2
GO:0007189	adenylate cyclase activating g protein coupled receptor signaling pathway	GO_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.295352060277795	1.19821247116717	0.170496388613511	0.606386590682829	63	GNAS,ADRB1,RXFP2,VIP,ADRB2,GNG2,DRD2,ADRA2C,GPR52,RAPGEF2,ADCY7,ADCY5,ADCY8,ADCY9,ADCY4,ADORA2B,GALR1,PTH,CALCR,OR5T1,PTH1R
GO:0051569	regulation of histone h3 k4 methylation	GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION	-0.381088688256763	-1.24938065863145	0.170602525661509	0.606386590682829	22	KDM1A,SNW1,GATA3,CTNNB1
GO:0030850	prostate gland development	GO_PROSTATE_GLAND_DEVELOPMENT	-0.318765438346693	-1.21385125369638	0.171063829787234	0.607384863991382	40	RARA,ID4,BMP4,WNT5A,FGFR2,FOXA1,CRIP1,ANXA1,CTNNB1
GO:0048016	inositol phosphate mediated signaling	GO_INOSITOL_PHOSPHATE_MEDIATED_SIGNALING	0.425116731301123	1.26289923302549	0.172072608242821	0.609842414799306	17	ITPR1,PLCE1,NFATC4,PPP3R1,NMUR2,NFATC1,PPP3CB,HRH1
GO:0002437	inflammatory response to antigenic stimulus	GO_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS	-0.356221616431303	-1.2332721937217	0.172118328597546	0.609842414799306	27	GATA3,HLA-DRB5,OPRM1,BDKRB2,HMGB2,IL2RA,IL25,HLA-DRB1,ELANE,IL20RB
GO:0045576	mast cell activation	GO_MAST_CELL_ACTIVATION	-0.391193753460444	-1.25008412836889	0.173295330925547	0.613367070342158	20	MRGPRX2,S100A12,NR4A3,SNAP23,LAT
GO:2000108	positive regulation of leukocyte apoptotic process	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	-0.35553805589218	-1.23090564389221	0.173968589616511	0.615103227572665	27	BBC3,WNT5A,ANXA1,NR4A3,HCAR2,LGALS16,FAS,PRELID1,BAX,SIRT1,IL10
GO:0030488	trna methylation	GO_TRNA_METHYLATION	0.403145904545071	1.25140722510437	0.174907475943745	0.61777393916752	20	NSUN2,ALKBH8,TARBP1,METTL1,METTL2B,TRMT1L,TRMT1
NA	regulation of protein complex assembly	GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY	0.214637094803167	1.11482689846268	0.175548589341693	0.619388418998048	342	TFIP11,CUL4A,SPTB,DDX3X,TUBGCP5,TMC8,PYDC2,CLASP1,TBCD,ULK1,XAF1,PSMC6,CLIP1,TUBGCP2,TAF1,CCL24,LMOD1,LMOD3,PINK1,FNIP1,STX1A,INPP5J,ARF1,PEX14,VPS11,ADD1,GSK3B,CAV3,SPIRE1,CSF3,VDAC2,ACTR3B,FAM21C,PPP1R9A,MED25,PSMC5,ERCC1,GTF2H3,LATS1,RAF1,CAPZB,MEFV,PRKCZ,ERCC4,WASL,TMOD1,SETX,MTOR,INSIG1,GBP5,TBX20,CREB1,FARP2,TNF,NKX2-5,CSF2,CTNNBIP1,CDKN1B,PARK7,SELP,HDAC6,VEGFA,BAG4,ARFGEF1,VCP,JMY,FHOD3,GTF2H5,FAF1,HEY2,TUBGCP6,IMPACT,RDX,C15orf62,MITF,MKKS,KANK1,HMGB1,CD36,FNIP2,MLST8,SUMO1,TPR,BCL11A,BID,STXBP6,PRKCE,TUBGCP3,PFN2,ARF6,GTF2F2,TLR4,CAPG,FOSL1,SRF,TWIST1,RRN3,PAXIP1,SPTBN1,MAPRE1,TMEM27,IRF8,SPIRE2,SEC24B,CHMP1B,CLASP2,HRK,BMF,GRB2,SIRT2,ARPC5L,CHMP4B,PLK1,VASP,HCFC1,HIST3H3,DKK1,CHMP4C,CDC42EP5
GO:0050962	detection of light stimulus involved in sensory perception	GO_DETECTION_OF_LIGHT_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION	-0.402683037781135	-1.25051359646225	0.176422147578286	0.621517634337831	18	CNGB1,BEST1,GUCY2F,GNAT1,CACNA1F,TULP1,CACNB4,EYS,GRM6,ATP8A2
GO:0019674	nad metabolic process	GO_NAD_METABOLIC_PROCESS	0.312945866064046	1.20533083189898	0.176521348314607	0.621517634337831	49	IDH3B,PGAM2,PGAM1,OGDH,HAAO,NMNAT3,PFKM,GCK,MDH2,MDH1,PFKFB4,PFKP,ALDOC,VCP,ALDOA,HK3,ENO2,DLST,NMNAT2,GPI,PGK1,IDH3G,GPD1L,NMNAT1
GO:0009250	glucan biosynthetic process	GO_GLUCAN_BIOSYNTHETIC_PROCESS	0.385735946240874	1.24370860884272	0.177069174534367	0.62229294713093	23	AKT2,PGM5,PHKG1,GYS1,GCK,GYG1,EPM2A,PRKAG3,PHKG2,PPP1R3C
GO:0000281	mitotic cytokinesis	GO_MITOTIC_CYTOKINESIS	-0.343865421312677	-1.22194680515602	0.17733902919498	0.62229294713093	30	CUL7,KIF20A,CEP55,ANLN,KIF4A,ZNF365,SNX33,RHOA,GTPBP8,SPAST,STMN1
GO:0042254	ribosome biogenesis	GO_RIBOSOME_BIOGENESIS	-0.209969083400076	-1.10832472146863	0.177385700324873	0.62229294713093	266	RPL24,NOC2L,RPL38,RBFA,RPL35,RPL30,RPL9,RPL3,RPS3A,RPS19,XRN2,RPS27,RPL4,RPS11,RSL24D1,RPL7A,RPS4Y1,NVL,WDR75,WDR46,RPS8,RPL18,NOC4L,NLE1,EXOSC2,NOP10,EXOSC6,RPS24,RPL18A,UBA52,RPL15,RPS16,WDR43,BRIX1,RPP25,RPL5,RPS27L,EXOSC5,NSA2,RPL10A,RPS3,RPL22,RPS29,RPL26,RPL19,KRR1,SART1,EXOSC10,RPS28,GNL2,RPS5,MINA,RPS17,DROSHA,EXOSC8,WDR36,PES1,DHX37,NHP2,RPF2,DDX21,PAPD5,RPL36,GNL1,RPS6,DDX51,RPP21,SIRT1,RPL23A,RPP30,RPS18,FAU,RPL32,BOP1,RPLP0,RPL14,NOP14,RPS15,RAN,RRP36,RIOK3,PNO1,RPS13,THUMPD1,RPL28,RPS4X,RPL34,NOL11,LAS1L
GO:0009142	nucleoside triphosphate biosynthetic process	GO_NUCLEOSIDE_TRIPHOSPHATE_BIOSYNTHETIC_PROCESS	0.311357303919055	1.20438106129576	0.177623783706151	0.62229294713093	50	ATP5L,CMPK2,AK1,UCKL1,ATP5A1,ATP5G2,ATP5D,AK4,ATP5O,ATP5B,NME6,ATP5G3
GO:0090501	rna phosphodiester bond hydrolysis	GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS	0.264550312190815	1.1678396335283	0.177689160495106	0.62229294713093	101	NOL9,DCP2,ELAC2,KIAA0391,NCBP1,SMG6,WDR33,EXOSC4,ABT1,EXOSC7,TUT1,RCL1,CLP1,RNASEH2C,PAN2,CNOT6L,CPSF1,EDC3,NCBP2,EXOSC3,MOV10,DICER1,PLD6,CNOT8
GO:0050771	negative regulation of axonogenesis	GO_NEGATIVE_REGULATION_OF_AXONOGENESIS	-0.28121108992976	-1.18166986063568	0.177850806636944	0.62229294713093	63	SEMA3F,SEMA3C,WNT5A,ULK2,RTN4,SEMA3A,SEMA3B,MAG,SEMA3D,CDK5,FGF13,SEMA3E,SEMA4B,RHOA,SEMA4A,FSTL4,PSEN1,RNF6,WNT3,SEMA7A,SPP1
GO:0000041	transition metal ion transport	GO_TRANSITION_METAL_ION_TRANSPORT	-0.253859769737918	-1.15810788484767	0.178416550155217	0.622995249798089	98	STEAP3,STEAP1,ATP6V1C2,SLC39A8,ATP6V1B1,SLC39A6,SLC39A2,ATP6V0D1,ATP6V1H,SLC30A2,CP,SLC39A10,SLC31A1,ATP13A1,SLC30A8,FTHL17,SLC30A9,ATP6V1A,ATP7B,STEAP1B,TTYH1,SLC39A1,SCARA5,SLC25A37
GO:0030878	thyroid gland development	GO_THYROID_GLAND_DEVELOPMENT	-0.372490454158283	-1.235485142284	0.178533801580334	0.622995249798089	23	PAX8,HOXA3,DUOX2,TG,MAP2K2
GO:0043401	steroid hormone mediated signaling pathway	GO_STEROID_HORMONE_MEDIATED_SIGNALING_PATHWAY	0.257119117618397	1.16043016627667	0.178606778388341	0.622995249798089	115	NR1I2,NR3C2,PPARD,ESRRA,NR2F6,PPARA,ESR1,RNF14,ABHD2,NKX3-1,JAK2,MED24,MED12,RXRB,UBR5,AR,RXRG,MED17,RHOXF1,ESR2,THRAP3,FHL2,RXRA,NCOA3,ESRRG,TRIP4,NCOA1,NR2F1,DDX54
NA	regulation of cyclic nucleotide metabolic process	GO_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS	0.24640940824988	1.15114380723558	0.179040553073097	0.623239453398627	145	GNAS,PDE5A,OPRL1,GUCY1A2,ADRB1,RXFP2,DRD4,VIP,ADRB2,CALM3,DRD2,ADCYAP1R1,CXCL11,GIPR,GLP1R,GUCY1A3,AKAP6,VIPR2,ADCY7,CXCR3,UCN,ADCY5,PDE2A,GUCA1C,EGLN1,CALM1,RAF1,P2RY13,ADCY8,ADCY9,HTR1E,CCR2,GABBR1,ADCY4,VEGFA
GO:0014888	striated muscle adaptation	GO_STRIATED_MUSCLE_ADAPTATION	0.385037955346301	1.24145811263428	0.179071305242276	0.623239453398627	23	CFLAR,HDAC4,KLF15,TCAP,HEY2,INPP5F,TRIM63,MEF2C,PPARGC1A,RPS6KB1
GO:0007006	mitochondrial membrane organization	GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION	0.274057061891348	1.17440632151297	0.179232261108102	0.623239453398627	85	RHOT2,LETM1,BAD,DYNLL2,ATPIF1,MFN2,TAZ,MOAP1,CAMK2A,GZMB,COX18,PPIF,GSK3B,CLN8,NMT1,PPP3R1,PPP1R13B,ATF2,TMEM102,TIMM22,BID,NDUFA13,OPA1,MAPK8,YWHAG,BAK1,TP53BP2
GO:0008380	rna splicing	GO_RNA_SPLICING	0.215262108149697	1.11418610929853	0.179941235940857	0.625059030110345	330	TFIP11,SF3A2,RALY,METTL3,ZBTB8OS,DGCR14,SNRNP35,RBM28,C1QBP,SNRNP70,NCBP1,ACIN1,HNRNPM,PRMT7,PRPF6,NOVA2,SNRNP200,SPEN,LGALS3,PRPF3,DHX8,PCBP2,RBM20,QKI,RBM10,KIAA1429,RAVER2,SNRPA,SF3B4,RBM17,SNRPN,CELF1,SCAF11,CLP1,DDX39B,TRPT1,LSM5,SRSF4,CDK12,PDCD7,PRPF39,HNRNPH3,CPSF1,DDX47,LUC7L,SFSWAP,POLR2I,SETX,CTNNBL1,THRAP3,LSM4,NCBP2,SRRT,XAB2,SMN1,PRPF31,HNRNPA2B1,RNPS1,AQR,SRSF1,SNRPC,PRPF19,SFPQ,SF3B3,RBFOX1,U2AF1L4,IVNS1ABP,CD2BP2,HTATSF1,SF1,LSM6,YBX1,JMJD6,SRRM2,DHX38,DDX20,GTF2F2,RBM5,POLR2C,RBM8A,SMNDC1,AKAP8L,PQBP1,DDX23,C2orf49,WBP11,PSPC1,FUS,PRPF4B,SUGP2,WDR77
NA	regulation of clathrin mediated endocytosis	GO_REGULATION_OF_CLATHRIN_MEDIATED_ENDOCYTOSIS	-0.426621059392993	-1.25681166056649	0.180269679458044	0.625073801006116	15	NLGN1,SNAP91,PROM2,TOR1A,DAB2,SCYL2
GO:0021983	pituitary gland development	GO_PITUITARY_GLAND_DEVELOPMENT	-0.315792603519723	-1.20253076895228	0.180873460246361	0.625073801006116	40	SOX3,KDM1A,BMP4,WNT5A,BMP2,DUOX2,POU3F2,SLC6A3
GO:0055024	regulation of cardiac muscle tissue development	GO_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.315095063284658	1.20279268183612	0.181018984610959	0.625073801006116	47	TBX2,PRICKLE1,PIN1,BMP10,GJA1,AKAP6,CAV3,DDX39B,TGFBR2,FGFR1,ERBB4,MTOR,TBX5,TBX20,NKX2-5,CDK1,HEY2,JPH2,FGF8
GO:1901685	glutathione derivative metabolic process	GO_GLUTATHIONE_DERIVATIVE_METABOLIC_PROCESS	-0.394394001995696	-1.24216522158083	0.181132977105869	0.625073801006116	19	GSTZ1,MGST1,GSTM3
GO:0060065	uterus development	GO_UTERUS_DEVELOPMENT	-0.416491281865931	-1.25145149694567	0.181353767560664	0.625073801006116	16	RBP4,WNT5A,GATA3,WNT9B,STRA6,FOXL2,WNT7A
GO:0044091	membrane biogenesis	GO_MEMBRANE_BIOGENESIS	0.355457827873995	1.22507778492036	0.181420206847491	0.625073801006116	30	NLGN3,IL1RAPL1,NRXN1,CDH2,PACSIN2,CAV3,PTEN,ANK3,NLGN4X,FLOT1,NLGN2,EMP2,SPTBN1,PEX3
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR	-0.296934302566507	-1.18922880573049	0.181467268623025	0.625073801006116	50	EDA2R,PHLDA3,SNW1,NUPR1,ZNF385C,TP73,BOK,PYCARD,CDKN1A,ZMAT3,RPS27L,BAX,WWOX
GO:0050878	regulation of body fluid levels	GO_REGULATION_OF_BODY_FLUID_LEVELS	-0.193042332972822	-1.0831927125399	0.181560611755182	0.625073801006116	475	VTN,PDPN,CLDN1,SCNN1A,PRKCA,C3,TYRO3,P2RX1,SFN,KDM1A,NPR1,CYP26B1,C11orf63,AQP1,DGKB,MYO5B,PROCR,HRNR,AQP3,SLC22A4,CD177,ENTPD2,HBE1,ANO6,GATA3,FAP,TREML1,C1QTNF1,ANXA5,SERPING1,DOCK11,TACR1,FLG,ANXA2,MMRN1,PRTN3,ACTG1,XBP1,ALOX12B,PAPSS2,ATP2B2,C4BPB,F7,NLRP6,SH2B1,HPSE,STXBP3,IFNA14,SLC6A3,GATA5,TMEM79,HIF1A,SERPINA5,F2,PLAUR,SAA1,ADAMTS18,PRKAR2B,HK2,VAMP8,SERPINB2,CYP4F11,S100A9,F13B,SCNN1G,NR1H3,PRKAR1B,ITPR3,EDNRB,PROS1,LAT,SCNN1B,ADCY2,PRKACG,CYP4F2,IFNA16,INPP5K,HIST1H3C,F5,CD34,KCNN4,STX2,STXBP1,RHOG,RAP2B,CAPZA1,VKORC1,THBS1,KRT16,F2RL3,PDPK1,NFE2,F2R,TXK,ATP7B,DGKA,RHOA,ABAT,GNA13,EDN1,PDGFD,VPS45,RAD51B,C1GALT1C1,NFE2L2,CDC42,SCARA5
NA	positive regulation of interleukin 1 secretion	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_SECRETION	-0.365822019271921	-1.22813969188417	0.181616808491973	0.625073801006116	24	CCL3,GSDMD,CCL19,WNT5A,PYCARD,SAA1,NLRP3,NLRP12,IFNAR1
GO:0071887	leukocyte apoptotic process	GO_LEUKOCYTE_APOPTOTIC_PROCESS	-0.387650304802164	-1.23876081635733	0.182955484965841	0.629037959545477	20	TRAF3IP2,TNFRSF21,RIPK1,HCAR2,FAS,BAX,IL2RA,RPS6
GO:0001944	vasculature development	GO_VASCULATURE_DEVELOPMENT	0.207030858765272	1.10171599655776	0.183255971227445	0.62942816239957	437	ROBO4,AMOT,LRP5,RAPGEF1,PROP1,NRP1,ATP7A,FBXW7,PDGFB,EPAS1,PTPRB,TBX2,NRXN1,NOTCH3,SERPINF2,ZNF304,TIE1,ATPIF1,PRICKLE1,RNF213,FLT1,AAMP,ITGB3,BMPER,MEGF8,HAND2,NDST1,EPHA1,CRKL,YAP1,CEACAM1,CDH2,CDX4,CDH5,QKI,EYA1,PRKX,NKX3-1,COL15A1,VEGFB,GJA1,CHD7,SUFU,FGF1,RAPGEF2,PTEN,TMEM204,DCTN5,NPRL3,CXCR3,ADIPOR2,SLC12A6,TGFBR2,HSPG2,NFATC4,ATP5B,TNNI3,E2F8,SIX1,HS6ST1,SHH,CX3CL1,DLL4,RASIP1,FGFR1,MYLK,ARHGAP22,TCF21,LTBP1,CDH13,GJA5,COL18A1,ZMIZ1,FOXO1,TBX5,TBX20,WARS,LUZP1,ANKRD17,TSPAN12,FLVCR1,S100A7,S1PR1,PDCD6,SEMA5A,NKX2-5,TEK,MCAM,MAPK1,SOX17,VEGFA,HOXB3,ETS1,ENG,PAX6,PLCD3,PLAU,SH2D2A,WNT11,CDX2,SPI1,HEY2
GO:0006760	folic acid containing compound metabolic process	GO_FOLIC_ACID_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.360773173593254	-1.22378762417539	0.184592735822109	0.632184846028726	25	SHMT1,ALDH1L1,GART,MTHFD1L,TYMS,DHFR,FTCD,ALDH1L2
GO:0060571	morphogenesis of an epithelial fold	GO_MORPHOGENESIS_OF_AN_EPITHELIAL_FOLD	-0.424500795887597	-1.25056543376079	0.184598402701123	0.632184846028726	15	RDH10,FGFR2,EGFR,HIF1A,NODAL,NOG,FGF10
GO:0051053	negative regulation of dna metabolic process	GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS	0.262103250289409	1.16131231794882	0.184622015343505	0.632184846028726	103	TFIP11,TRIP12,FBXW7,SMG6,ZNF91,MCRS1,GJA1,OBFC1,FBXO18,ZRANB3,DACH1,UBR5,ERCC1,GTPBP4,SMC1A,LIG3,ERCC4,ACD,TERF2IP,APOBEC3D
GO:0006544	glycine metabolic process	GO_GLYCINE_METABOLIC_PROCESS	-0.424289254334317	-1.24994223927706	0.185031275025431	0.632371537982011	15	SHMT1,GART,TDH,GLYAT,AGXT2,DHFR,AGXT
GO:0002755	myd88 dependent toll like receptor signaling pathway	GO_MYD88_DEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	-0.338435855859371	-1.21225403144856	0.18505227715754	0.632371537982011	31	IRAK4,LY96,IRAK1,UBA52,IRAK3,TLR10,TLR9,TLR2,UBB,TAB2
GO:0007265	ras protein signal transduction	GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION	0.249713689228895	1.15115190918075	0.185249788314987	0.632404449764957	132	RASGRP2,GNA12,RAPGEF1,MAPKAPK2,ZNF304,TIAM1,ALS2,RAPGEF6,ROCK2,RASGRP3,PLD1,CRKL,MAPKAPK3,MYO9B,PLCE1,RAPGEF2,CFL1,SETDB1,LIMK1,MAPKAPK5,RAP2C,CDH13,DBNL,FARP2,BRAP,RALGDS,PARK7
GO:2000352	negative regulation of endothelial cell apoptotic process	GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS	-0.355562969653595	-1.21869876381228	0.185799441303917	0.633495192234572	26	SCG2,KDR,ANGPT1,GATA3,ANGPTL4,NFE2L2,ABL1,IL10,KRIT1,GAS6
GO:0045981	positive regulation of nucleotide metabolic process	GO_POSITIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS	0.253016616724073	1.15326665128021	0.185945707049244	0.633495192234572	122	GNAS,GUCY1A2,ADRB1,RXFP2,VIP,ADRB2,CALM3,ADCYAP1R1,CXCL11,GIPR,PINK1,GLP1R,GUCY1A3,VIPR2,PRKAA2,ADCY7,CXCR3,UCN,ADCY5,GCK,GUCA1C,CALM1,RAF1,ADCY8,ADCY9,PARK7,ADCY4,VCP,P2RX7,CXCL9,ADORA2B
GO:0002705	positive regulation of leukocyte mediated immunity	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.276332314778622	1.17223980781391	0.186342693971936	0.633635795892877	80	RSAD2,STAT5B,CRTAM,UNG,XCL1,HSPD1,CD40,HLA-B,STX4,PRKCZ,IL4,TNF,EXOSC3,P2RX7,SH2D1B,MALT1,ADORA2B,PTAFR,IL2,ZP3,SH2D1A,TNFSF4,IL21,PAXIP1,AP1G1,NOS2,HLA-E,IL12RB1,FOXP3,STX7,RASGRP1,GAB2,TRAF6
GO:1902750	negative regulation of cell cycle g2 m phase transition	GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.382231872464704	1.23241060365572	0.186363469380258	0.633635795892877	23	FOXN3,TAOK3,CDK5RAP3,CDK1,HUS1,CLSPN,FOXO4,MRE11A
GO:0090103	cochlea morphogenesis	GO_COCHLEA_MORPHOGENESIS	0.392454347704948	1.2352050264701	0.187198936935939	0.635412351489448	21	ZEB1,DVL2,GLI2,EYA1,SIX1,SOX9,HPN,POU3F4
GO:0010464	regulation of mesenchymal cell proliferation	GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION	0.341222105803701	1.21135120815349	0.187263533178114	0.635412351489448	34	LRP5,ZEB1,FBXW4,NFIB,TGFBR2,SIX1,SHH,FGFR1,CTNNBIP1,VEGFA,SOX9,WNT11
GO:0042762	regulation of sulfur metabolic process	GO_REGULATION_OF_SULFUR_METABOLIC_PROCESS	0.411133980128799	1.2403877769972	0.187719330820506	0.636317489971625	18	DLAT,DLD,PDHA1,PDHX,PDP1,PDHB,PDPR
GO:0035019	somatic stem cell population maintenance	GO_SOMATIC_STEM_CELL_POPULATION_MAINTENANCE	0.290973462762999	1.18044895821414	0.188712646933862	0.636786579712957	63	CUL4A,LRP5,ZHX2,EPAS1,EPHA1,BCL9L,YAP1,SOX2,RAF1,POLR2I,FOXD3,LDB1,SOX9,CDX2,SPI1,LDB2
GO:0033500	carbohydrate homeostasis	GO_CARBOHYDRATE_HOMEOSTASIS	-0.229068402542554	-1.12661048638729	0.188903763200952	0.636786579712957	157	CMA1,RBP4,CNR1,PYGL,NMB,PTPN2,FOXA1,SESN2,XBP1,MEN1,GK,STAT3,CEBPA,STAR,HIF1A,ADIPOQ,LEP,SLC18A2,HK2,PPARG,PCK1,POMC,SLC16A1,FAS,KCNB1,SIRT6,SLC30A8,INPP5K,IL1R1,FOXA3,STXBP5L,CARTPT,CYB5R4,CYP7A1,GCGR,BHLHA15,FOXO3,FGFR4,HNF4A,PTGER4,RPS6,SIRT1,G6PC
GO:0007059	chromosome segregation	GO_CHROMOSOME_SEGREGATION	0.224844289221467	1.12121695637557	0.189144790345142	0.636786579712957	237	GSG2,NDE1,TOP3B,SPAG5,DDX3X,CENPK,FBXW7,CIAO1,POGZ,SUN1,CLASP1,CENPA,PAFAH1B1,AKAP8,VPS4A,DMC1,RANGAP1,NCAPH,CLIP1,NUP85,MAD2L1,SYCP2,TEX11,CHMP7,RAD21L1,TTN,SMC1A,CEP85,TLK2,LATS1,SPO11,FAM83D,SMC2,ERCC4,MAU2,MLH3,KIFC1,NEK9,INCENP,RECQL5,RGS14,CENPN,NAA50,NCAPD3,DLGAP5,SETDB2,HFM1,KIF25,CEP57L1,BAG6,CENPI,CHMP6,KLHL22,ZWILCH,MAD1L1,MRE11A,CKAP5,UBE2B,UVRAG,MMS19,UBE2I,ESPL1,CCDC155,AKAP8L,DIS3L2,BRCA2,TOP2B,MAPRE1,CHMP1B,PAPD7,CLASP2,PHF13,KPNB1,CENPO,ARL8B,CHMP4B,CENPT,MLH1,SKA2,PLK1,CHMP4C,MEI1,KIF23,PPP1CC,PPP1R7,NCAPD2,FAM96B,PPP2R1A
NA	regulation of interleukin 8 secretion	GO_REGULATION_OF_INTERLEUKIN_8_SECRETION	-0.397296820458062	-1.23378694705303	0.189164589879727	0.636786579712957	18	WNT5A,ANXA4,ANXA1,PYCARD
GO:0050905	neuromuscular process	GO_NEUROMUSCULAR_PROCESS	0.269200187594007	1.16337166633672	0.189275710284114	0.636786579712957	89	HERC1,GRIN3A,SCN1A,NRXN1,DLG4,PAFAH1B1,APP,SHANK1,DRD2,ABR,FABP7,GRIN2C,PTEN,UCN,CLN8,ADCY5,POU4F3
GO:0002252	immune effector process	GO_IMMUNE_EFFECTOR_PROCESS	-0.194790805730046	-1.08361999470907	0.189353503639218	0.636786579712957	434	RAET1E,GCNT3,IFITM2,MRGPRX2,CFB,C3,CD55,C4A,POLR3D,C2,CCL3,CFI,ANXA3,CFH,C9,IRAK4,C4BPA,TRIM11,AGBL5,SLFN11,FCGR2A,GATA3,CEBPB,MASP2,HLA-DRB5,C1RL,ARPC5,SERPING1,MB21D1,C1R,C1S,ACTG1,ACTR3,FUT7,C4BPB,POLR3G,PYCARD,NR4A3,APOBEC3F,STXBP3,IFNA14,SNAP23,EXOSC6,BAIAP2,FCN3,IRF7,IRF4,ULBP3,IGHG4,MASP1,CEBPG,IGHG2,VAMP8,EXOSC5,IGHG1,IFNE,NKX2-3,EIF2AK4,LAT,MBL2,RAET1G,FAS,APBB1IP,C5,CLEC4E,IGHD,IFNA16,NLRP3,IFNAR1,IGKC,WIPF2,RNF8,DNAJC3,COLEC10,HSP90AA1,POU2F2,SEMA4A,IGLL1,UNC93B1,IGLC1,CDC42,HLA-DRB1,GPAM,ELANE,PTGER4,IFI16,DLG1,GNL1,GBP3,RPS6,CXCL5,ABL1,PSEN1,ULBP2,CARD9,NBN,SWAP70,IL4R,CD46
GO:0009065	glutamine family amino acid catabolic process	GO_GLUTAMINE_FAMILY_AMINO_ACID_CATABOLIC_PROCESS	0.386139423068243	1.22994070376484	0.18988786801937	0.636786579712957	22	PPAT,ASRGL1,GLUD1,GOT2,PRODH2,GOT1,GLUD2,ARG1,NOS2,GAD2,DDAH1,ASL
GO:0042044	fluid transport	GO_FLUID_TRANSPORT	-0.35415101572014	-1.21385926515769	0.189956668059741	0.636786579712957	26	PDPN,AQP1,AQP3,AQP8,EDNRB,AQP11,EDN1,AQP9,AHCYL1,AQP10,PDZD3
GO:0045777	positive regulation of blood pressure	GO_POSITIVE_REGULATION_OF_BLOOD_PRESSURE	0.337757486034326	1.20679250334503	0.1900018178513	0.636786579712957	35	AGT,ADRB1,HSD11B2,ADRB2,WNK1,ADH5,TACR3,GLP1R
GO:0010952	positive regulation of peptidase activity	GO_POSITIVE_REGULATION_OF_PEPTIDASE_ACTIVITY	-0.231649514628585	-1.12881191077721	0.190118654916055	0.636786579712957	147	BBC3,P2RX1,DAP,IFT57,SFRP2,CTGF,CYR61,MAPK12,CYCS,SNCA,PCOLCE,STAT3,BOK,PYCARD,BCAP31,RIPK1,ACVR1C,TRADD,SEMG2,EIF2AK3,CASP3,RPS27L,RPS3,PPARG,S100A9,DAPK1,ARL6IP5,FAS,PRELID1,NLRP3,NLRP12,BAX,NOD1,ASPH,F2R,NEK5,NODAL,SENP1,MYC,IFI16,PCOLCE2,F3,SIRT1,PAWR,RET,FOXL2,MMP14,ANP32B
GO:0001916	positive regulation of t cell mediated cytotoxicity	GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY	0.433399342839872	1.24535891569918	0.190245171843343	0.636786579712957	15	XCL1,HLA-B,P2RX7,HLA-E,IL12RB1,STX7,HLA-A
GO:0072073	kidney epithelium development	GO_KIDNEY_EPITHELIUM_DEVELOPMENT	-0.24029085032249	-1.13662235883615	0.19034318606854	0.636786579712957	122	WNT6,PAX8,OSR1,RARA,WT1,BMP4,BMP2,NPNT,GATA3,FGFR2,SDC1,UMOD,SIM1,POU3F3,CTNNB1,CAT,NPHS1,WNT7B,ROBO2,SMAD2,IRX1,MAGI2,GDNF,CD34,WNT9B,PKD2,BASP1,MYC,DLG1,ADAMTS16,IRX2,RET,PODXL,BCL2,FGF2
GO:0001731	formation of translation preinitiation complex	GO_FORMATION_OF_TRANSLATION_PREINITIATION_COMPLEX	-0.396706324878811	-1.23195319027357	0.190378155813198	0.636786579712957	18	EIF3H,EIF3L,EIF2D,DENR,EIF4H,EIF3G,EIF2S3,EIF4B
NA	positive regulation of cyclic nucleotide metabolic process	GO_POSITIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS	0.26259415711942	1.15768040224338	0.190622465356274	0.636786579712957	100	GNAS,GUCY1A2,ADRB1,RXFP2,VIP,ADRB2,CALM3,ADCYAP1R1,CXCL11,GIPR,GLP1R,GUCY1A3,VIPR2,ADCY7,CXCR3,UCN,ADCY5,GUCA1C,CALM1,RAF1,ADCY8,ADCY9
GO:0032459	regulation of protein oligomerization	GO_REGULATION_OF_PROTEIN_OLIGOMERIZATION	-0.349772384407523	-1.2109443557722	0.190863234873015	0.636786579712957	27	MMP1,BBC3,SH3GLB1,SORL1,FAS,OPRD1,BAX
GO:0002253	activation of immune response	GO_ACTIVATION_OF_IMMUNE_RESPONSE	-0.197724468182348	-1.08769255777944	0.190884628321561	0.636786579712957	386	CFB,C3,CD55,C4A,C2,CFI,CFH,C9,IRAK4,COLEC12,C4BPA,TNFRSF21,FCGR2A,LY96,KRAS,GATA3,MASP2,SCARA3,CD79B,HLA-DRB5,C1RL,ARPC5,SERPING1,MB21D1,C1R,C1S,ACTG1,ACTR3,IRAK1,C4BPB,PYCARD,NR4A3,RIPK2,RIPK1,CHUK,BAIAP2,FCN3,UBA52,IRF7,IGHG4,IRAK3,TLR10,MASP1,CNPY3,IGHG2,IGHG1,C5AR1,IKBKG,PSMB11,PAK3,CTSK,LAT,MBL2,PGLYRP1,PSMD10,C5,CLEC4E,IGHD,PRKACG,TLR9,BAX,NOD1,GRAP2,IGKC,CACNB4,PDPK1,WIPF2,TXK,COLEC10,HSP90AA1,CUL1,PSMD5,PSMD13,TLR2,IGLL1,PSMB5,UNC93B1,IGLC1,CDC42,HLA-DRB1,UBB,IFI16,IKBKE,ABL1,PSEN1,CARD9,PSMA6,PSMA4,CD46,PLD2,BCL2,TAB2,CFHR5,RAC1,PIK3R4,HRAS,PDE4B,PGLYRP2,ZAP70
GO:0032609	interferon gamma production	GO_INTERFERON_GAMMA_PRODUCTION	-0.421715517588101	-1.24236009516426	0.191134774798173	0.636989754426387	15	IL18,GATA3,VTCN1,TRIM27,AVPR2,EOMES,AZI2,BTN3A2
GO:0007528	neuromuscular junction development	GO_NEUROMUSCULAR_JUNCTION_DEVELOPMENT	0.339877733022852	1.20657863461681	0.191647264260768	0.637553529145045	34	APP,ALS2,LRRK2,CACNA2D2,MUSK,LAMB2,PDZRN3,DNAJA3
GO:0009636	response to toxic substance	GO_RESPONSE_TO_TOXIC_SUBSTANCE	-0.214996098540726	-1.10882953726315	0.191682760396549	0.637553529145045	220	ASS1,CCL3,GRIA4,GSTZ1,HP,NUPR1,ALPL,MGST1,DUOX2,SDC1,SCFD1,GSTM3,SKIL,TXNDC2,CRIP1,TXNDC17,CAT,DDC,SLC7A8,CDKN1A,CHUK,STAR,HIF1A,CPS1,DHX15,RAB10,TYMS,GLYAT,CASP3,CCNB1,PLA2G4F,SLC18A2,GPX8,S100A9,TRPM6,NQO1,GJC2,FAS,HMBS,CDH1,OPRD1,SLC22A8,PTGR1,BLMH,PTGS1,APOM,FABP1,BAX,SLC6A14,HSP90AA1,AHR,CYB5R4,TTPA,CCL4
GO:0034644	cellular response to uv	GO_CELLULAR_RESPONSE_TO_UV	-0.278115343016398	-1.16866130245759	0.192305924530036	0.638994809445313	63	NOC2L,KDM1A,AQP1,POLH,CRIP1,HIST3H2A,TP73,CDKN1A,YY1,MME,DDB2,ZBTB1,EIF2AK4,XPC,AURKB,BAX,CDC25A,TRIAP1,MDM2,MYC
GO:0002446	neutrophil mediated immunity	GO_NEUTROPHIL_MEDIATED_IMMUNITY	-0.377839702326892	-1.22324282506191	0.192496562561383	0.638997465070626	21	ANXA3,IRAK4,STXBP3,VAMP8,ELANE,CXCL5
GO:0072329	monocarboxylic acid catabolic process	GO_MONOCARBOXYLIC_ACID_CATABOLIC_PROCESS	0.268376111938724	1.15981035281446	0.193468691824556	0.641591740572862	89	SLC25A17,DECR1,IVD,PPARD,LPIN1,ACOX3,ACAD9,ACADM,MMAA,ACAD10,CRYL1,CEL,PLA2G15,HADH,ECI2,GOT2,ETFA,PEX7,ACOT8,HADHB,PCCB,ECHS1,HOGA1,GCDH,ACADVL,PCCA,HADHA
GO:0031061	negative regulation of histone methylation	GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION	0.431670840189601	1.24039211955173	0.194167177828584	0.642326733980047	15	SMARCB1,JARID2,BCOR
GO:0061077	chaperone mediated protein folding	GO_CHAPERONE_MEDIATED_PROTEIN_FOLDING	-0.31230503098636	-1.18925017519049	0.194221724524076	0.642326733980047	40	FKBP11,PPIB,PDIA4,CALR,CANX,TOR1A,TTC9B,TTC9,CRTAP,FKBP10,TOR2A,ST13,FKBP7
GO:2000737	negative regulation of stem cell differentiation	GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION	-0.316595316079144	-1.19086216298014	0.194262809029022	0.642326733980047	38	VASN,PAX8,SFRP2,FOXA1,TRIM62,MSTN,BMP5
GO:0010522	regulation of calcium ion transport into cytosol	GO_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL	0.270899903728582	1.16087707151378	0.195079761675956	0.643606544486512	85	PRKACA,ANK2,CALM3,RYR2,CAPN3,XCL1,ATP1A2,HRC,ADCYAP1R1,CXCL11,AKAP6,DMD,CXCR3,PLN,SLC8A1,CALM1,CACNA1C,P2RX7,CYBA,CXCL9,PLCG1,HTT,TRDN,JPH2,PRKCE,DHRS7C,BAK1
GO:1901293	nucleoside phosphate biosynthetic process	GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS	0.239094309317635	1.13368850380911	0.195210923511989	0.643606544486512	161	TK1,ATP5L,ME1,PANK3,CMPK2,GUCY1A2,UPP2,AK1,PPAT,UCKL1,GUCY1B3,ATP5A1,ATP5G2,HAAO,ATP5D,OAS2,GUCY1A3,COASY,AK4,PRPSAP2,NMNAT3,ADCY7,NPR2,ATP5O,ADCY5,ATP5B,NME6,ADA,ATP5G3,GUCY2C,ADCY8,ADCY9,OAS1,ADSSL1,PANK4,ADCY4
GO:0040017	positive regulation of locomotion	GO_POSITIVE_REGULATION_OF_LOCOMOTION	-0.19690527292612	-1.08450745492517	0.195223494331767	0.643606544486512	391	SEMA3F,VTN,SEMA3C,PRKCA,IL16,SCG2,CCL3,ITGA3,CCL19,BDKRB1,ANXA3,KDR,TGFBR1,PRKD1,BMP4,WNT5A,CCAR1,TRIM11,BMP2,FAM110C,MET,RETN,CCR6,TNFSF14,FGF7,ANO6,ANGPT1,GATA3,MAP2K2,LPAR1,FOXF1,ITGB1BP1,CYR61,IQCF1,CALR,SEMA3A,SEMA3B,TACR1,ACVR1,SRPX2,CXCL1,INSL3,FGF18,F7,MIA3,PYCARD,ANGPTL3,CCL21,CSF1,EGFR,ANGPT4,HIF1A,ARTN,RHOD,DAB2,SEMA3D,GRB7,C5AR1,TRIM38,SPARC,SMURF2,RARRES2,RAPGEF3,TMPRSS2,ONECUT1,HGF,CMKLR1,SEMA3E,THBS1,DOCK7,ADAM9,ZNF703,F2R,SEMA4B,ACVR1B,INSM1,CCL4,SEMA4A,FSHB,CPNE3,EDN1,PDGFD,PTGER4,THBS4,F3,CXCL5,PAWR,RET,PODXL,DIAPH1,SUN2,SWAP70,PF4,RAB11A,MMP14,BCL2,FGF2,PDCD10
GO:0050806	positive regulation of synaptic transmission	GO_POSITIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION	0.258082690459698	1.15076891975217	0.195589826375174	0.644183322484183	107	LAMA2,SHANK3,NLGN3,LRRTM2,NRXN1,DLG4,SLC24A2,DRD4,KIF5B,SHANK1,DRD2,VAMP2,PINK1,STX1A,GSK3B,PTEN,RAB3GAP1,NPS,STX4,PRKCZ,RGS14,SYT12,MAPK1,CA2
GO:0060706	cell differentiation involved in embryonic placenta development	GO_CELL_DIFFERENTIATION_INVOLVED_IN_EMBRYONIC_PLACENTA_DEVELOPMENT	-0.361113209074626	-1.21233124843301	0.195872444951312	0.644449069562662	24	KRT8,KRT19,GRHL2,ST14,STK3
GO:0006323	dna packaging	GO_DNA_PACKAGING	0.238809513196964	1.13341604119743	0.196099095030194	0.644449069562662	162	HILS1,NASP,CENPK,NPM1,PAF1,HIST1H2BO,CENPA,ACIN1,AKAP8,NCAPH,HIST1H3G,HIST1H3B,HMGA1,HELLS,PRM1,HIST1H4F,HP1BP3,HIST1H2BC,KAT6A,TTN,PSME4,H3F3A,HIST1H2BA,SMC2,H2BFWT,CENPN,CDK1,NCAPD3,HIST1H3E,ASF1B,SOX9,ATRX,HIST2H2BE,HMGB1,CENPI,UBN1,TSPYL5,ASF1A,H1F0,HIST2H2BF,H1FX,KAT6B,AKAP8L,HIST1H4A,HIST1H1D,AIFM1,PAPD7,PHF13,SART3,CENPO,HIST1H1T,CENPV,CENPT,TSPYL6,HIST3H3
GO:0046785	microtubule polymerization	GO_MICROTUBULE_POLYMERIZATION	0.365466116385807	1.21525301866869	0.196244888978529	0.644449069562662	26	NDE1,TUBGCP5,CLASP1,TUBGCP2,GOLGA2,TUBG1,TUBGCP6,TUBGCP3
GO:0030308	negative regulation of cell growth	GO_NEGATIVE_REGULATION_OF_CELL_GROWTH	-0.228046465548563	-1.1215843678957	0.196712777034062	0.645355952725783	157	SEMA3F,SEMA3C,ING1,BDKRB1,NPR1,WT1,WNT5A,TP53TG5,ULK2,SFRP2,ADAM15,RTN4,CDKN2C,SEMA3A,SEMA3B,GAS2L1,SLIT3,CDKN1A,RERG,ST7L,FBP1,SEMA3D,CDK5,NOV,PPARG,FGF13,DCUN1D3,SEMA3E,SERTAD3,GAL,SEMA4B,ACVR1B,SEMA4A,FSTL4,GNG4,HNF4A,INHBA,SIRT1,RNF6,BCL2,WNT3,DNAJC2,SH3BP4
GO:0055078	sodium ion homeostasis	GO_SODIUM_ION_HOMEOSTASIS	-0.344103523273961	-1.20222282887224	0.197519694595847	0.64661933214147	28	SGK2,MC3R,SCNN1A,TMPRSS3,SGK1,SCNN1G,SCNN1B,CYP4F2,ATP4A,ATP1B1,ATP1A1
GO:0010765	positive regulation of sodium ion transport	GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT	0.346581224074804	1.20408455451538	0.197801596850049	0.64661933214147	31	DRD4,ADRB2,SCN5A,WNK2,ARF1,DMD,PKP2,FXYD1,GLRX,NKX2-5,CNTN1,ANK3,FGF12,CNKSR3,ATP1B2
GO:0097305	response to alcohol	GO_RESPONSE_TO_ALCOHOL	-0.200042582295501	-1.08808516137407	0.197855964815833	0.64661933214147	347	ASS1,SLC34A1,C3,RBP4,CNR1,CCL3,SSTR3,MLC1,RARA,CA9,TGFBR1,AQP1,AREG,RBBP8,BMP4,WNT5A,AQP3,SSTR2,ALPL,CTGF,GATA3,PEMT,FOXA1,TSPO,OPRM1,CALR,ANXA1,SOCS1,TACR1,MBD3,KLF4,HTR3A,CTNNB1,GK,CAT,STAT3,GRIN2A,SLIT3,ERRFI1,PIM1,CDKN1A,SLC6A3,EGFR,STAR,MSX2,HIF1A,CPS1,LRP8,HTR1B,MSTN,ADIPOQ,TYMS,CASP3,LEP,CHRNB2,SLC18A2,SMAD2,HTR5A,CA3,SPARC,ABCA1,NQO1,CCNA2,FAS,HMBS,CDH1,PTGS1,CYP1A2,NEU2,MYOD1,ADCYAP1,BAX,KLF6,SPTBN2,MSN,ZNF703
GO:0006835	dicarboxylic acid transport	GO_DICARBOXYLIC_ACID_TRANSPORT	-0.271947144390656	-1.15941968130477	0.197866284048043	0.64661933214147	68	SLC1A6,PDPN,SLC26A9,SNAP25,SLC1A1,SLC38A2,SLC17A7,PRAF2,SLC25A22,SLC1A4,FOLR3,UNC13B,ARL6IP5,SLC13A5,AGXT,STXBP1
GO:0010837	regulation of keratinocyte proliferation	GO_REGULATION_OF_KERATINOCYTE_PROLIFERATION	-0.351332333041114	-1.20419817727822	0.19877702747289	0.648046051194199	26	TGM1,SFN,PRKD1,FGF7
GO:0070570	regulation of neuron projection regeneration	GO_REGULATION_OF_NEURON_PROJECTION_REGENERATION	-0.393542195093235	-1.22212713119833	0.198786434066529	0.648046051194199	18	PTPRF,MAP2K2,KLF4,CERS2,HGF,STK24,KLK8,SPP1
GO:0032205	negative regulation of telomere maintenance	GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE	0.368743384780091	1.2140148456278	0.199060395294636	0.648046051194199	25	SMG6,MCRS1,ERCC1,ERCC4,ACD,TERF2IP
GO:0051261	protein depolymerization	GO_PROTEIN_DEPOLYMERIZATION	-0.365218346995872	-1.21136484536912	0.199297629499561	0.648046051194199	23	KIF2C,KIF18A,STMN3,SGK1
GO:1905144	response to acetylcholine	GO_RESPONSE_TO_ACETYLCHOLINE	-0.40902901266076	-1.22902925577514	0.199385241465896	0.648046051194199	16	AGRN,RGS8,HRH4,CHRM4
GO:0070372	regulation of erk1 and erk2 cascade	GO_REGULATION_OF_ERK1_AND_ERK2_CASCADE	-0.214798062722599	-1.10582866494494	0.199542287022037	0.648046051194199	217	PLA2G2A,CHI3L1,PRKCA,C3,EZR,CCL3,TNFSF11,CCL19,ARHGEF5,KDR,BMP4,BMP2,PTPN2,CTGF,NPNT,ANGPT1,FSHR,ALOX15,FGFR2,ITGB1BP1,CYR61,OPRM1,PRMT5,ATF3,KLF4,FGF18,NLRP6,ERRFI1,PYCARD,CCL21,RIPK2,EGFR,FGF4,ADIPOQ,ABCA7,TNFAIP8L3,C5AR1
GO:0031167	rrna methylation	GO_RRNA_METHYLATION	0.42932059695407	1.23363877205413	0.199650551125486	0.648046051194199	15	FTSJ3,TFB2M,EMG1,METTL16,NSUN4,METTL15,NSUN3,MRM1
GO:0002675	positive regulation of acute inflammatory response	GO_POSITIVE_REGULATION_OF_ACUTE_INFLAMMATORY_RESPONSE	-0.343117993483918	-1.19877960225006	0.200940044574884	0.650634048116102	28	C3,CNR1,TNFSF11,FFAR3,OSMR
GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR	-0.37464467037878	-1.21289902084467	0.201161090377354	0.650634048116102	21	TAF9B,KDM1A,MUC1,RRM2B,BDKRB2,TRIAP1,MIF,UBB,SIRT1
GO:1901570	fatty acid derivative biosynthetic process	GO_FATTY_ACID_DERIVATIVE_BIOSYNTHETIC_PROCESS	-0.308524955990551	-1.18177471919163	0.201626271224408	0.650634048116102	41	PTGIS,ALOX15,TBXAS1,AKR1C3,PLA2G4F,GGT1,PTGS1,MIF,EDN1,FCER1A,PLA2G4A,ALOX5AP,PTGES,GGT6,ALOX5
GO:0035235	ionotropic glutamate receptor signaling pathway	GO_IONOTROPIC_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY	-0.359284493292707	-1.2061918737682	0.201859812264234	0.650634048116102	24	GRIA4,GRID1,GRIA2,GRIN2A,GRID2,GRIN2D,GRIN3B,GRIK2,CPEB4,CLN3
NA	azole transport	GO_AZOLE_TRANSPORT	-0.417101437947611	-1.22876716774713	0.201913295673441	0.650634048116102	15	SLC22A3,SNAP23,SLC19A3,SLC35F3,SLC38A1,ADCYAP1,EDN1
GO:0036336	dendritic cell migration	GO_DENDRITIC_CELL_MIGRATION	-0.380406783235396	-1.21561368973781	0.202036464905792	0.650634048116102	20	CCL19,ARHGEF5,CCR6,ANO6,CCL21,NLRP12,CDC42
GO:0031112	positive regulation of microtubule polymerization or depolymerization	GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION	0.38701852682835	1.21809640400476	0.202074451396194	0.650634048116102	21	TUBGCP5,CLASP1,CLIP1,TUBGCP2,CAV3,CDKN1B,TUBGCP6,TUBGCP3
GO:0002861	regulation of inflammatory response to antigenic stimulus	GO_REGULATION_OF_INFLAMMATORY_RESPONSE_TO_ANTIGENIC_STIMULUS	-0.392182603936045	-1.21790498358302	0.202145411203814	0.650634048116102	18	C3,CNR1,NLRP6,ADCYAP1,FCER1A,IL20RB,IL10
GO:0001573	ganglioside metabolic process	GO_GANGLIOSIDE_METABOLIC_PROCESS	0.376289924946956	1.21325228731748	0.202288674185372	0.650634048116102	23	ST6GALNAC4,ST8SIA6,ST3GAL6,ST3GAL3,ST3GAL2,NEU3,ST6GALNAC3
GO:0010862	positive regulation of pathway restricted smad protein phosphorylation	GO_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION	-0.298643650887802	-1.17434707657657	0.202425499301204	0.650634048116102	46	GDF5,TGFBR1,BMP4,BMP2,GDF10,ACVR1,LEFTY1,MSTN,BMP5,DAB2
GO:0032371	regulation of sterol transport	GO_REGULATION_OF_STEROL_TRANSPORT	-0.321377067907272	-1.18660894482381	0.202613798008535	0.650634048116102	35	APOA2,APOC1,TSPO,ADIPOQ,LEP,ABCA7,PPARG,ABCA1,PLTP,NR1H3,ABCG1,LRP1,SIRT1,LAMTOR1
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	-0.252970024267972	-1.14121196642648	0.202895128344393	0.650634048116102	92	TNFRSF8,CCL3,CCL19,RARA,LY96,ANGPT1,TBC1D23,CIDEA,TSPO,ERRFI1,PYCARD,RIPK2,RIPK1,ADIPOQ,IRAK3,ORM1,POMC,TLR9,CD34,THBS1,NOD1
GO:0031122	cytoplasmic microtubule organization	GO_CYTOPLASMIC_MICROTUBULE_ORGANIZATION	0.324220234156639	1.18803593926174	0.203278629265471	0.650634048116102	39	TUBGCP5,CLASP1,PAFAH1B1,VPS4A,KATNAL1,TUBGCP2,IFT172,FIGNL2,CAV3,TUBG1,TUBGCP6,TRDN,TUBGCP3,KATNAL2,ATAD1,KPNB1,FIGN
GO:0048385	regulation of retinoic acid receptor signaling pathway	GO_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY	-0.358717387992474	-1.20428798474019	0.203416966400561	0.650634048116102	24	PRAMEF4,CYP26B1,SNW1,CYP26A1,CALR,AKR1C3
GO:1903959	regulation of anion transmembrane transport	GO_REGULATION_OF_ANION_TRANSMEMBRANE_TRANSPORT	0.358954958020704	1.2048367127186	0.203761698075197	0.650634048116102	27	SLC17A3,AKT2,CLCN6,CLCN4,VDAC2,VDAC3,ANO1,MTOR,GRK6,VDAC1,PTAFR,BSND
GO:0034698	response to gonadotropin	GO_RESPONSE_TO_GONADOTROPIN	-0.358577836816869	-1.20381948276716	0.203833669620142	0.650634048116102	24	ITGA3,PAX8,FOXM1,WT1,STAR,CCNA2
GO:0060976	coronary vasculature development	GO_CORONARY_VASCULATURE_DEVELOPMENT	0.331182785126036	1.19119393290661	0.203918367346939	0.650634048116102	36	NRP1,PRICKLE1,MEGF8,HAND2,NDST1,VEGFB,SUFU,DCTN5,LTBP1,TBX5,VEGFA,HEY2
GO:0055075	potassium ion homeostasis	GO_POTASSIUM_ION_HOMEOSTASIS	0.404631364899343	1.22076944127461	0.204300276658559	0.650634048116102	18	ATP1A2,KCNJ2,KCNH2,KCNA5,KCNMA1,ATP1A3,ATP1B2
GO:0046883	regulation of hormone secretion	GO_REGULATION_OF_HORMONE_SECRETION	0.22130306442929	1.11036406683424	0.204368098954117	0.650634048116102	250	P2RY1,LRP5,AGT,GNAS,BAD,PPARD,TRPM4,BMP8A,SYT9,ITPR1,NRXN1,PDE8B,RAPGEF4,NPY1R,TIAM1,CACNA2D2,DRD2,OPRK1,CDK16,VAMP2,GHSR,ADRA2C,GIPR,STX1A,NKX3-1,GJA1,GLP1R,HMGCR,OSM,CHD7,SYT7,PDE4C,JAK2,REST,SLC25A4,SIRT4,UCN,PFKM,IRS1,ADCY5,GCK,AGTR2,ANO1,HADH,STX4,GLUD1,CACNA1C,KCNA5,CREB1,TNF,GABBR1
GO:0000578	embryonic axis specification	GO_EMBRYONIC_AXIS_SPECIFICATION	-0.329219277531577	-1.18889121840858	0.204541926326761	0.650634048116102	32	TBX6,WT1,WNT5A,T,TMED2,COBL,CTNNB1,SMAD2
GO:0071354	cellular response to interleukin 6	GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_6	-0.37344332003314	-1.20900969110605	0.204784041554814	0.650634048116102	21	PTGIS,ENTPD2,STAT3,IL6ST,SELPLG
GO:0043267	negative regulation of potassium ion transport	GO_NEGATIVE_REGULATION_OF_POTASSIUM_ION_TRANSPORT	0.347843615803792	1.19883556622266	0.204841033872645	0.650634048116102	30	VIP,NEDD4L,CAV3,PLCB4,KCNH2,KCNA5,KCNRG,ANK3,SUMO1,CASQ2,ACTN2,KCNAB1,KCNQ1,CAB39,AKAP5,NOS3
GO:0061377	mammary gland lobule development	GO_MAMMARY_GLAND_LOBULE_DEVELOPMENT	-0.415629595347613	-1.22443116767993	0.205181481721966	0.650634048116102	15	TPH1,TNFSF11,AREG,FOXF1,HIF1A
GO:0000186	activation of mapkk activity	GO_ACTIVATION_OF_MAPKK_ACTIVITY	0.307196879937814	1.17804665146376	0.20521488940838	0.650634048116102	48	RAPGEF1,TAOK2,TNIK,FLT1,ZAK,LRRK2,MAP3K15,CRKL,JAK2,MAP3K4,RAF1
GO:0007289	spermatid nucleus differentiation	GO_SPERMATID_NUCLEUS_DIFFERENTIATION	-0.398326566794193	-1.2182038231296	0.205757667517411	0.650634048116102	17	AGFG1,PYGO1,TSSK6,HMGB2,TMF1,PYGO2,CHD5
NA	regulation of organ formation	GO_REGULATION_OF_ORGAN_FORMATION	-0.328915457268361	-1.18779404923422	0.205783859306735	0.650634048116102	32	SULF1,WT1,BMP4,WNT5A,BMP2,WNT2B,CTNNB1
GO:0050892	intestinal absorption	GO_INTESTINAL_ABSORPTION	-0.353509429890576	-1.19914809912428	0.206038100678957	0.650634048116102	25	GCNT3,EZR,NPC1L1,TJP2,LEP,FABP1,F11R
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS	0.30253686075439	1.17582845840071	0.206040316516882	0.650634048116102	51	MADD,TMC8,CFLAR,LGALS3,ARHGEF2,SP100,FEM1B,PTEN,RAF1,STX4,TNFRSF10B,TNFSF10,PARK7,MAL,TIMP3,FAF1
GO:1901998	toxin transport	GO_TOXIN_TRANSPORT	0.333033065352903	1.18991235798414	0.206053444828213	0.650634048116102	35	SLC17A3,NRP1,LRP6,HRH2,COPZ1,TCP1,RAB28,TRIP4,CCT3,CRTC2,CCT6B,CCT7,CCT4,BNIP3,MEP1B,DNAJC17,CCT8,GGA1
GO:0060326	cell chemotaxis	GO_CELL_CHEMOTAXIS	-0.229411069628073	-1.11790412458025	0.206341391364285	0.650932636674962	147	IL16,SCG2,CCL3,CCL28,TNFSF11,CCL19,PIP5K1A,ARHGEF5,CCR6,ANO6,LPAR1,RPS19,ANXA1,AGTR1,CXCL1,S100A12,PARVA,CCL21,ARHGEF16,RAB13,SAA1,IL17RC,C5AR1,NOV,S100A9,EDNRB,HGF,C5,RHOG,EPHA2,HMGB2
GO:0030225	macrophage differentiation	GO_MACROPHAGE_DIFFERENTIATION	-0.384710770583488	-1.21166736098483	0.206720535210044	0.65151809130806	19	BMP4,CEBPA,CSF1,L3MBTL3,NKX2-3,CDC42,CEBPE,SIRT1
NA	regulation of tyrosine phosphorylation of stat3 protein	GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN	-0.305047814745653	-1.17537775196877	0.207188018474508	0.652380608218142	42	IL18,ARL2BP,PTPN2,SOCS1,CLCF1,STAT3,IL6ST,IL20,LEP,IL24
GO:0061245	establishment or maintenance of bipolar cell polarity	GO_ESTABLISHMENT_OR_MAINTENANCE_OF_BIPOLAR_CELL_POLARITY	-0.32493397251732	-1.18248203478871	0.207481937857364	0.652695516661578	33	EZR,WNT5A,PTK7,PRKCI,FOXF1,CRB2,PDZD11,DLG5,LIN7B,MSN,CDC42,DLG1
GO:0072273	metanephric nephron morphogenesis	GO_METANEPHRIC_NEPHRON_MORPHOGENESIS	-0.372474679534978	-1.20587375136191	0.207795892533665	0.653072805105804	21	PAX8,WT1,BMP4
GO:0043648	dicarboxylic acid metabolic process	GO_DICARBOXYLIC_ACID_METABOLIC_PROCESS	0.262326299105278	1.14462744554287	0.208219273017083	0.653792978521923	94	IDH3B,ME1,STAT5B,DDO,DLD,CYP17A1,MTHFR,OGDH,HAAO,FPGS,NMNAT3,MDH2,MDH1,FH,IDH2,GLUD1,GOT2,ADSSL1,LIPF,ADHFE1,SLC25A32,ACOT8,MDH1B,PRODH2,IDH1,GOT1,HOGA1,GLUD2,DLST,SHMT2,NMNAT2,TH,NIT2,SDHB,ACMSD,SDHA,D2HGDH,IDH3G,L2HGDH,GAD2,NMNAT1
GO:0034111	negative regulation of homotypic cell cell adhesion	GO_NEGATIVE_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	0.260438691596596	1.14413259168829	0.208674290261751	0.65400202135019	98	CTLA4,PDE5A,SCGB1A1,ADRB2,HLX,XCL1,LGALS3,SPN,CEACAM1,ZC3H8,PELI1,PRKAR1A,CD300A,IDO1,LAX1,SHH,IRF1,DTX1,IL4,DUSP3,RDX,HMGB1,PAG1,GNRH1,MAD1L1,LILRB1,BCL6,TNFRSF14,PRKG1,FOXJ1,TNFSF4
GO:0048661	positive regulation of smooth muscle cell proliferation	GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION	0.291315159602571	1.16582910063336	0.208742527754056	0.65400202135019	59	PDGFB,STAT5B,NOTCH3,SERPINF2,FLT1,HMGCR,HDAC4,GSK3B,DDX39B,TGFBR2,CX3CL1,CDH13,MTOR,S1PR1,TNF,NPY5R,CYBA
GO:0051180	vitamin transport	GO_VITAMIN_TRANSPORT	-0.337603907199173	-1.1896347510089	0.208868738250581	0.65400202135019	29	PDPN,AMN,SLC19A3,SLC35F3,FOLR3,TTPA,SLC2A2,SLC2A1,SLC23A2,LMBRD1,STRA6
GO:0002220	innate immune response activating cell surface receptor signaling pathway	GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY	0.258766384287621	1.14230687120841	0.209315172544755	0.654790772105617	101	PRKACA,PSMD11,CREBBP,PSMD2,UBE2N,PSMC6,FCN1,BTRC,CLEC6A,PSMC5,PSMB7,PSME4,ICAM3,ICAM2,RAF1,EP300,IKBKB,PSMA8,PSMD8,PSMB10,MALT1,PSMD3,PSMB1,NFKB1,PSMA5,PSMB9,NFKBIA,PSMD6,PRKACB,PSMB3,PSMB6,PSMD1
GO:0042391	regulation of membrane potential	GO_REGULATION_OF_MEMBRANE_POTENTIAL	0.212254406552604	1.09769062551426	0.209623569993196	0.65487761680452	328	SHANK3,AGT,CNGA2,NLGN3,KCNH7,BAD,TRPM4,SCN7A,ANK2,SCN1A,NRXN1,DLG4,KCNMB3,CATSPER2,CTNNA3,ATPIF1,DRD4,SLC26A4,ADRB2,DMPK,SCN5A,LRRK2,CACNA2D1,KCNK13,RYR2,KIF5B,DLD,SHANK1,TPCN1,NEDD4L,ATP1A2,RNF207,KCNJ2,SLC25A36,KCNK9,PINK1,STX1A,GJA1,GRIN2C,GSK3B,AKAP6,CAV3,PTEN,DMD,RAB3GAP1,PKP2,FXYD1,PLN,PPP1R9A,SLC8A1,KCNH2,NPS,SLC26A5,CX3CL1,GRIK5,PRKCZ,GLRX,NDUFS1,CACNA1C,GJA5,KCNA5,SCN3A,PARK7,KCNMA1,BEST2,VCP,CACNA1B,SLC26A7,P2RX7,SOD1,PIAS3,ANK3,SLC26A3,ZMYND8,KCNIP2,GJC1,SMAD7,FAM19A4,CATSPER4,FGF12,CACNA1E,TRDN,ATP1A3,SUMO1,ATP2A2,NPFF,NLGN4X,SNTA1,PRDX3,NLGN2,KCND3,BAK1,RIMS3,ATP1B2,MTMR2,MEF2C,JUP,KCNK6,POPDC3,DSP,SLC9A3R2
NA	regulation of interferon gamma biosynthetic process	GO_REGULATION_OF_INTERFERON_GAMMA_BIOSYNTHETIC_PROCESS	-0.405215963096938	-1.21757200134428	0.209775526549343	0.65487761680452	16	IL27,CEBPG,TLR9,INHBA,CD276,TLR3,TNFRSF13C
GO:0019226	transmission of nerve impulse	GO_TRANSMISSION_OF_NERVE_IMPULSE	-0.288999448988298	-1.16189086793908	0.209926603841972	0.65487761680452	51	SCN4A,P2RX1,CACNG4,DRD5,KCNMB2,SPTBN4,CACNG3,CACNA1I,KCNA1,CACNG2,GRIK2,CACNB4,NRCAM
GO:1904035	regulation of epithelial cell apoptotic process	GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS	-0.282407228751556	-1.15784397001443	0.210352523228275	0.655052391226234	56	SCG2,KDR,BMP4,ANO6,ANGPT1,GATA3,PRKCI,XBP1,AKR1C3,ANGPTL4
GO:1902668	negative regulation of axon guidance	GO_NEGATIVE_REGULATION_OF_AXON_GUIDANCE	-0.343735047969059	-1.19004253844766	0.210599352408643	0.655052391226234	27	SEMA3F,SEMA3C,WNT5A,SEMA3A,SEMA3B,SEMA3D,SEMA3E,SEMA4B,SEMA4A
GO:0010038	response to metal ion	GO_RESPONSE_TO_METAL_ION	-0.201636072361087	-1.08583492351457	0.210753500418162	0.655052391226234	315	ASS1,ATP13A2,SLC34A1,C3,DTYMK,MT1M,KHK,LIPC,ALDOB,KCNMB2,MT1E,AQP1,WNT5A,AQP3,TNFRSF11B,ALOX15,SDC1,ANXA5,MT2A,KCNH1,TSPO,CRIP1,TAT,PKLR,SNCA,CALR,SLC18A1,MT1A,CTNNB1,CAT,SLC30A2,CP,CEBPA,AKR1C3,MT1F,SLC6A3,STAR,HIF1A,CPS1,EIF2AK3,ZACN,FBP1,FABP4,CASP3,CCNB1,SLC18A2,MT1G,KEAP1,SPARC,KRT14,RYR3,ITPR3,FAS,HMBS,CDH1,CPNE6,SLC30A8,KCNA1,CYP1A2,THBS1,BAX,ASPH,ADAM9,CYB5A,ATP7B,ABAT,MDM2,CPNE3,SEC31A,EDN1,JUNB,GUCA1A,GPAM
GO:0032924	activin receptor signaling pathway	GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY	-0.377134521904565	-1.20515697380775	0.210761063487229	0.655052391226234	20	TGFBR1,ACVR1,ACVR1C,SMAD2,ACVR2B,ACVR1B,NODAL,INHBA
GO:0032411	positive regulation of transporter activity	GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY	0.281742171595792	1.15755085893505	0.211262149598535	0.656004054934196	67	SHANK3,NLGN3,ANK2,DRD4,CALM3,CACNA2D1,RYR2,S100A1,WNK1,RNF207,WNK2,AKAP6,DMD,CALM1,GLRX,PARK7,ANK3,PTAFR,HTT,TRDN,SUMO1,JPH2
GO:0009880	embryonic pattern specification	GO_EMBRYONIC_PATTERN_SPECIFICATION	-0.283075541633218	-1.15663123717484	0.212024020745189	0.657148837521573	55	SEMA3F,TBX6,WT1,WNT5A,T,FGFR2,TMED2,SEMA3A,COBL,CTNNB1
GO:0051290	protein heterotetramerization	GO_PROTEIN_HETEROTETRAMERIZATION	-0.336541003180317	-1.1858893335808	0.212097755169745	0.657148837521573	29	NLGN1,S100A10,HIST1H4C,ANXA2,CNGA4,HIST1H4D,HIST1H4E,HIST1H3C
GO:0090207	regulation of triglyceride metabolic process	GO_REGULATION_OF_TRIGLYCERIDE_METABOLIC_PROCESS	0.348643021975048	1.19157043889941	0.212440907514556	0.657148837521573	29	FBXW7,ATG14,FITM2,ESR1,APOC3,LDLR
GO:0008333	endosome to lysosome transport	GO_ENDOSOME_TO_LYSOSOME_TRANSPORT	0.324058061358424	1.18105085960223	0.212463411990026	0.657148837521573	38	TRAK1,DENND3,KIF13A,ATG14,ADRB2,RAB12,VPS11,VPS39,CDX2,SORT1,GPRASP1
GO:0009309	amine biosynthetic process	GO_AMINE_BIOSYNTHETIC_PROCESS	-0.382815310711305	-1.20569750769037	0.212606976845215	0.657148837521573	19	HDC,TPH1,DDC,SAT1,ODC1,SMOX,OAZ3
GO:0010594	regulation of endothelial cell migration	GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.256449192908602	1.13828408813519	0.213013368246968	0.657349476600035	104	AMOT,AGT,PTPRM,NRP1,PDGFB,HDAC9,CSNK2B,ATOH8,AAMP,ROCK2,ITGB3,BMPER,SASH1,BMP10,SP100,FGF1,STARD13,AGTR2,DLL4,FGFR1,AMOTL1,CCR2,PDCD6,SEMA5A,TEK,VEGFA,ETS1,HSPB1
GO:0071295	cellular response to vitamin	GO_CELLULAR_RESPONSE_TO_VITAMIN	-0.365091876545112	-1.19693589244401	0.213368059355234	0.657349476600035	22	PIM1,LEP,PPARG,MDM2,PAWR,ATP2B1,GAS6,FGF23,FOLR2,COL1A1,TNC
GO:0050715	positive regulation of cytokine secretion	GO_POSITIVE_REGULATION_OF_CYTOKINE_SECRETION	-0.25239892868125	-1.13419189869238	0.213469108738184	0.657349476600035	90	CCL3,GSDMD,CCL19,WNT5A,GATA3,XBP1,PYCARD,LPL,SAA1,IL17RC,CLEC5A,IL17F,C5,CLEC4E,NLRP3,NLRP12,CD34,IFNAR1,F2R,MIF,VTCN1,IL17RB,MAPK11,PTGER4,ABL1,CD276,IL4R,IL10
GO:1903649	regulation of cytoplasmic transport	GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT	0.20392670019677	1.08635256210417	0.213734947161465	0.657349476600035	443	PRKACA,PARL,PIK3R1,RBCK1,FBXW7,PYDC2,ANK2,GPHA2,ATPIF1,RAB21,EDEM2,LRRK2,NUDT4,CALM3,AKAP1,RANGAP1,ITGAX,RYR2,RNF31,CAPN3,XCL1,ATP1A2,HRC,C8orf4,ADCYAP1R1,SP100,CXCL11,PINK1,STX1A,STARD7,BAP1,ARF1,PLAGL2,ABLIM3,VPS11,SUFU,PKIA,GSK3B,AKAP6,JAK2,DDX58,SIAH3,CSF3,HUWE1,DMD,SIRT4,RAB3GAP1,CXCR3,CYB5R1,CABP1,PLN,RGS20,IFI27,MBTPS1,SLC8A1,PSMB7,AGTR2,KAT2A,UBR5,PDE2A,DERL3,SHH,CALM1,SAE1,XPO4,KHDRBS1,GRIK5,EP300,ERBB4,PPP3R1,CACNA1C,MTOR,INSIG1,IL18R1,NCBP2,YOD1,TNF,SEMA5A,TMEM173,EMD,ARIH2,PARK7,MAPK1,CDK1,PPP1R12A,PSMD8,BAG4,P2RX7,CYBA,USP36,FAF1,CXCL9,RDX,PLCG1,KANK1,MDFI,HYAL2,CD36,HTT,SMAD3,TRDN,TPR,AAAS,ATP2A2,KCNN3,JPH2,PRKCE,BAMBI,LITAF,RANBP3,PFN2,NFKBIA,EGF,RAB3A,TLR4,TGFB3,FAM89B,MED1,DHRS7C,RINT1,BAK1,AKAP8L,RIMS3,EDA,PRKCQ,WBP11,MTMR2
GO:0015850	organic hydroxy compound transport	GO_ORGANIC_HYDROXY_COMPOUND_TRANSPORT	-0.230381403350167	-1.11511874912265	0.213743645160498	0.657349476600035	141	SCN4A,CFTR,RBP4,P2RX1,APOA2,APOC1,LIPC,EMB,AQP1,SLC10A3,AQP3,SLC22A4,SLC10A1,AQP8,NPC1L1,SNCA,SLC18A1,ABCG4,SLC22A3,ABCB11,SLC6A3,STAR,ABCA7,SLC18A2,ABCA1,SLC16A1,APOM,SLCO1B3,SLC44A5,AQP11
GO:0045471	response to ethanol	GO_RESPONSE_TO_ETHANOL	0.245903799540559	1.13031290949047	0.213959081363051	0.657349476600035	129	CHAT,USP46,BAD,GRIN3A,STAT5B,CYP2E1,HDAC2,DRD4,CCND1,DRD2,OPRK1,ADCYAP1R1,HMGCR,PTEN,ADCY7,SETDB1,ALAD,EP300,ATP5G3,GOT2,ESR2,IL4,HMGCS2,GABBR1,SETD7,RXRA,ADH7,CDK1,SLC2A4,SOD1,SPI1,ST6GAL1,MAOB,CRHBP,IL2,GNRH1,PTH,PRKCE,APOBEC1,NTRK3,BAK1,TH,ADH6,LCT
GO:0033555	multicellular organismal response to stress	GO_MULTICELLULAR_ORGANISMAL_RESPONSE_TO_STRESS	0.285651548763718	1.15885850877417	0.214257895482226	0.657349476600035	63	SLC6A2,USP46,ADRB1,DRD4,ALS2,ADCYAP1R1,OSM,PTEN,UCN,IDO1,FBXL20,ESR2,HMGCS2,VDAC1,CACNA1B,NMUR2
GO:0014044	schwann cell development	GO_SCHWANN_CELL_DEVELOPMENT	0.363416331764229	1.19647657453838	0.214347323411206	0.657349476600035	25	LAMA2,AKT2,SH3TC2,LAMB2,MED12,SOD1,DICER1
NA	regulation of tyrosine phosphorylation of stat1 protein	GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT1_PROTEIN	-0.403410982961657	-1.21214849023947	0.214429508409637	0.657349476600035	16	PTPN2,SOCS1,IL6ST,TNFRSF1A
GO:0001909	leukocyte mediated cytotoxicity	GO_LEUKOCYTE_MEDIATED_CYTOTOXICITY	0.333244171659477	1.18302924424845	0.21469368451688	0.657560456855158	34	UNC13D,CRTAM,GZMB,KIR3DL1,KLRF2,VAMP2,CTSH,ULBP1,MICA
GO:0052646	alditol phosphate metabolic process	GO_ALDITOL_PHOSPHATE_METABOLIC_PROCESS	-0.326247421205929	-1.17815911938197	0.215541904149387	0.658452414164603	32	PLA2G2A,LIPC,GPD1,PLA2G16,PLA2G2D,GK,PLA2G4F,SERINC2,LPCAT3
GO:0071695	anatomical structure maturation	GO_ANATOMICAL_STRUCTURE_MATURATION	-0.313216381636283	-1.17149434608895	0.21563721657545	0.658452414164603	37	BMP2,RYR1,ANO6,GATA3,THBS3,CEND1
GO:0002181	cytoplasmic translation	GO_CYTOPLASMIC_TRANSLATION	-0.31525422081159	-1.17178934824188	0.215678409875883	0.658452414164603	36	RPL22L1,RPL9,RPL15,EIF2D,CDC123,RPL22,RPL26,DENR,EIF4H,FTSJ1,RPL36,EIF4EBP1,PTBP1,RPLP0
GO:0009395	phospholipid catabolic process	GO_PHOSPHOLIPID_CATABOLIC_PROCESS	-0.335549669461558	-1.18239611263005	0.215901802499171	0.658452414164603	29	SMPDL3B,APOA2,SMPD3,LIPC,SMPDL3A,ANGPTL3,PLA2G4F
GO:0045931	positive regulation of mitotic cell cycle	GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE	0.250893461204472	1.13233252976286	0.215963002150244	0.658452414164603	115	CUL4A,LRP5,DDX3X,PCID2,PDGFB,STAT5B,PAFAH1B1,APP,CREBBP,CCND1,MAD2L1,GOLGA2,NKX3-1,USP2,SMARCD3,PTEN,GORASP1,TGFA,KCNA5,ANAPC11,ANKRD17,CDK1,DLGAP5,DUSP3,RDX,ASNS,TPR,FGF8,EGF,ESPL1,CYP1A1,PPP1R1C,BRCA2,EREG,PHOX2B,NSMCE2,SIN3A,PLK1,RPS6KB1,USP22,MEPCE,DRD3,MTBP
GO:0060291	long term synaptic potentiation	GO_LONG_TERM_SYNAPTIC_POTENTIATION	0.325192472313395	1.1778669618098	0.216286184984702	0.658840994261093	37	NLGN3,LRRTM2,SLC24A2,VAMP2,PTEN,STX4,PRKCZ,RGS14,SYT12,MAPK1
GO:0032365	intracellular lipid transport	GO_INTRACELLULAR_LIPID_TRANSPORT	0.399619779235478	1.20564952927199	0.21765044469614	0.662056059042805	18	LRP6,VPS4A,PRKAB2,SYT7,PRKAA2
GO:0051984	positive regulation of chromosome segregation	GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION	0.38147124940136	1.20063698483636	0.217762028680582	0.662056059042805	21	GOLGA2,PTEN,GORASP1,ANAPC11,DLGAP5,SFPQ,ESPL1,NSMCE2,SIRT2,PLK1
GO:0043627	response to estrogen	GO_RESPONSE_TO_ESTROGEN	-0.214385255052993	-1.0969623292447	0.217931703333163	0.662056059042805	207	ASS1,SLC34A1,KRT19,C3,DTYMK,APOA2,SSTR3,RARA,AREG,RBBP8,BMP4,WNT5A,SSTR2,CTGF,TNFRSF11B,GATA3,LDHA,FOXA1,GSTM3,CALR,ANXA1,SOCS1,TACR1,MBD3,CTNNB1,F7,CAT,STAT3,EGFR,STAR,MSX2,HIF1A,MSTN,CASP3,LEP,PPARG,HTR5A,NQO1,CCNA2,SFR1,FAS,HMBS
GO:0042246	tissue regeneration	GO_TISSUE_REGENERATION	-0.298324847066499	-1.16131807520822	0.218922139532792	0.664465213406112	44	PAX7,GAP43,ADAM15,ANXA1,WNT10B,IGFBP1,MSTN,CCNB1,TM4SF4,NOV,MYOD1,SOX15,TXK,PTPN12,EYS
GO:1903523	negative regulation of blood circulation	GO_NEGATIVE_REGULATION_OF_BLOOD_CIRCULATION	0.337250242252903	1.18069645775066	0.219883083535175	0.666144190013141	32	PDE5A,ATP1A2,HMGCR,JAK2,PLN,DOCK4,AGTR2,CX3CL1,IL2,ATP2A2,NPFF,ADM,UTS2,PIK3CG
GO:0050918	positive chemotaxis	GO_POSITIVE_CHEMOTAXIS	-0.32496171409208	-1.17351611697774	0.21993302432858	0.666144190013141	32	SCG2,CCL3,BMP4,WNT5A,MET,FGF7,ANGPT1,SAA1,HGF,HMGB2,ALKBH1,MIF
GO:0009235	cobalamin metabolic process	GO_COBALAMIN_METABOLIC_PROCESS	0.380707213540989	1.19823226963661	0.220069025340051	0.666144190013141	21	CUBN,MMAA,MTR,ABCC1,MMACHC,CTRC
GO:0006066	alcohol metabolic process	GO_ALCOHOL_METABOLIC_PROCESS	0.211242141249734	1.09223981365188	0.220935567051081	0.668166324073621	327	IDI2,CNBP,CHAT,LRP5,PLCB2,LSS,CYP4V2,PPARD,LPIN1,MOGAT1,PCYT1A,DMGDH,CUBN,PAFAH1B1,APP,DBI,ALDH7A1,NUDT4,CALM3,CHPT1,VLDLR,PLA2G4C,LDLR,CYP17A1,PLCH1,LCAT,ADH5,PCSK9,PLA2G5,CEL,RPE65,INPP5J,HMGCR,INPPL1,PLCE1,LPCAT4,IMPA2,PTEN,ITPK1,MVD,CYP27B1,CYP51A1,PRKAA2,INPP5D,ACER2,CYB5R1,CYP7B1,INPP1,CLN8,SARDH,MBTPS1,PLCB4,IP6K3,GGPS1,PLA2G15,SMPD4,MSMO1,CALM1,IP6K2,MBOAT2,IPMK,INSIG1,IL4,PCYT1B,HMGCS2,PARK7,RXRA,ADH7,CELA3A,HMGCS1,PLA2G4E,SQLE,PLCD3,FDX1,NPC1,GALK1,CETP,SGPP1,PLCG1,GOT1,PTAFR,ITPKC,CYP3A4,IDI1,SGMS1,APOL1,APOL2,FDFT1,INPP5A,ITPKB,TNFSF4,PNPLA6,SLC27A1,ITPKA,CYP1A1,CHKA,MBOAT1,DPM2,SCP2,PLA2G4D,NSDHL,APOA5,MTMR2,ADH6,COQ2,OSBPL1A,HSD17B3
GO:0070987	error free translesion synthesis	GO_ERROR_FREE_TRANSLESION_SYNTHESIS	-0.392175778543866	-1.19939284142151	0.222260673962884	0.671499862394975	17	RPA3,POLH,UBA52,RPA2,UBB,PCNA,RFC1,RPS27A,RCHY1,RFC4,RFC2
NA	positive regulation of receptor activity	GO_POSITIVE_REGULATION_OF_RECEPTOR_ACTIVITY	0.313313190571782	1.16708483421726	0.222436823104693	0.671499862394975	42	SHANK3,NLGN3,FBXW7,CALM3,ADRA2C,AKAP6,RXRB,TGFA,CALM1,PARK7,NCOA3,HTT,TRDN,JPH2,PRKCE,EGF,MED1,EREG,ACTN2
GO:0030177	positive regulation of wnt signaling pathway	GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY	0.239549270366249	1.11909549667141	0.223016609054886	0.672092470420893	145	TRPM4,BIRC8,CSNK2A1,LRP6,DVL2,PSMD11,DIXDC1,PPP2R3A,LRRK2,PIN1,PSMD2,PSMC6,RNF220,ZRANB1,YAP1,ZEB2,MACF1,PSMC5,PSMB7,PSME4,UBR5,SHH,GPRC5B,ANKRD6,DAPK3,PSMA8,PSMD8,PSMB10,PSMD3,PSMB1,KANK1,NFKB1,SMAD3,LGR5,LRRK1,PSMA5,MLLT3,PSMB9,BAMBI,ATP6V0C,EDA,PSMD6,JUP,USP34,PSMB3,PSMB6,CTDNEP1,PSMD1
GO:0043277	apoptotic cell clearance	GO_APOPTOTIC_CELL_CLEARANCE	-0.348197984009621	-1.18113101190338	0.223110896266837	0.672092470420893	25	TYRO3,RARA,ALOX15,PDIA6,FCN3,NR1H3,THBS1,LRP1
GO:0045806	negative regulation of endocytosis	GO_NEGATIVE_REGULATION_OF_ENDOCYTOSIS	0.328336412892649	1.17313142724475	0.22323213961098	0.672092470420893	35	LRSAM1,LRRTM2,DLG4,UNC119,APOC3,LGALS3,PACSIN2,PTEN,CD300A
NA	negative regulation of neurological system process	GO_NEGATIVE_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS	-0.408122332297385	-1.20231501674755	0.223816635283423	0.672703222507583	15	TNFRSF21,NPY2R,EIF2AK3,NOV,HCRT,KLK8,CALCA,IFNG,AVP,MTNR1B
GO:0050890	cognition	GO_COGNITION	0.221785782895901	1.1028733912881	0.22383470267632	0.672703222507583	231	CPEB3,SHANK3,CHAT,NLGN3,GNAS,ITGA8,NRXN1,GPR155,DLG4,SLC24A2,DRD4,VIP,PAFAH1B1,APP,ADRB2,NDRG4,VLDLR,HRH2,SHANK1,OR52B4,MUSK,ATP1A2,DRD2,OPRK1,SLC6A1,GLP1R,HMGCR,CHD7,GPR52,RASGRF1,PTEN,UCN,CLN8,GRIA1,NPS,NPTX2,EP300,PRKCZ,PAIP2,ADCY8,ESR2,MTOR,CREB1,TMPRSS11E,RGS14
GO:0009584	detection of visible light	GO_DETECTION_OF_VISIBLE_LIGHT	-0.300541553476569	-1.15801470596677	0.225034751804852	0.675706489362294	42	CNGB1,BEST1,GUCY2F,PDE6C,GNAT1,CACNA1F,OPN1LW,TULP1,AIPL1,OPN3,CACNB4,RS1,GNGT1,EYS,GRM6,ATP8A2,PDE6G,PDE6A,OPN1SW
GO:0048167	regulation of synaptic plasticity	GO_REGULATION_OF_SYNAPTIC_PLASTICITY	0.242617018178296	1.12105053485087	0.225487210718636	0.676187932344356	134	CPEB3,SHANK3,AGT,NLGN3,LRRTM2,DLG4,SLC24A2,CAMK2A,HRH2,DRD2,VAMP2,ARF1,RASGRF1,GSK3B,RAPGEF2,PTEN,ABHD6,RAB3GAP1,GRIA1,PPP1R9A,NFATC4,STX4,PRKCZ,PAIP2,CREB1,CAMK2B,RGS14,SYT12,MAPK1
GO:0030517	negative regulation of axon extension	GO_NEGATIVE_REGULATION_OF_AXON_EXTENSION	-0.312643958508299	-1.16208709094857	0.225772667513426	0.676187932344356	36	SEMA3F,SEMA3C,WNT5A,RTN4,SEMA3A,SEMA3B,SEMA3D,CDK5,SEMA3E,SEMA4B,SEMA4A
GO:0002792	negative regulation of peptide secretion	GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION	0.300661941476708	1.15801851802164	0.225797752808989	0.676187932344356	49	BMP8A,PDE8B,DRD2,GHSR,HMGCR,PDE4C,REST,SIRT4,IRS1,HADH
GO:0010565	regulation of cellular ketone metabolic process	GO_REGULATION_OF_CELLULAR_KETONE_METABOLIC_PROCESS	0.236482551034644	1.11485031001783	0.226281900801502	0.677035447198095	154	AKT2,DLAT,PSMD11,PPARA,APOC3,PSMD2,PSMC6,DLD,GHSR,PRKAB2,PDHA1,REST,LONP2,PRKAA2,DKK3,SIRT4,SIRT5,IRS1,PSMC5,PSMB7,PSME4,KAT2A,WDTC1,PDHX,MTOR,INSIG1,FOXO1,PDP1,PSMA8,PARK7,PSMD8,PDHB,PSMB10,APC,TRIB3,FABP3,PDPR,PSMD3,PSMB1,ACACB,OAZ1,ACADVL,PSMA5,PSMB9,PRKCE,HPN,PROX1,APOA5,PSMD6,GCG,TWIST1,ACMSD,PSMB3,PSMB6,PSMD1
GO:0007093	mitotic cell cycle checkpoint	GO_MITOTIC_CELL_CYCLE_CHECKPOINT	0.244333424677751	1.12101838415776	0.226555623264947	0.67725242265525	127	PPP2R5C,FOXN3,NPM1,CSNK2A1,CCND1,TAOK3,MAD2L1,PLAGL1,CDK5RAP3,TFDP2,CNOT6L,SMC1A,CNOT4,PRCC,DGKZ,EP300,FBXO31,INTS3,CDKN1B,CDK1,ATF2,APC,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,CLSPN,GIGYF2,KLHL22,FOXO4,TPR,ZWILCH,PRKDC,MAD1L1,MRE11A,CHFR,CNOT1,MAD2L1BP,TIPIN
GO:0044706	multi multicellular organism process	GO_MULTI_MULTICELLULAR_ORGANISM_PROCESS	0.225545036315674	1.1032145862287	0.227100618991176	0.677853854586713	203	TK1,AGT,GNAS,PPARD,IL11RA,SCGB1A1,STAT5B,DDO,HSD11B2,ADRB2,PPAT,ESR1,PLA2G4C,GHSR,ADRA2C,TAC3,CYP27B1,ADCY7,UCN,ADIPOR2,STC2,TGFBR2,IDO1,PSG5,PSG1,MMP7,MTOR,IL4,SEMG1,RPL29,RXRA,ETS1,DEDD,SOD1,PSG7,PLAU,SLC38A3,CRHBP,PTAFR,OVGP1,CD38,ABCG2,GNRH1,APOL2,CAD,DHODH,NPFF,KPNA6,LNPEP,TGFB3,PRDX3,MED1,CYP1A1,EMP2,EDDM3A,FOSL1,ADM,NR2F2,MAFF,UMPS,PSG6,PGF,KLK14
GO:0070227	lymphocyte apoptotic process	GO_LYMPHOCYTE_APOPTOTIC_PROCESS	-0.398710682704598	-1.19802527074148	0.227200900491374	0.677853854586713	16	TRAF3IP2,TNFRSF21,RIPK1,FAS,BAX,IL2RA,RPS6
GO:0031113	regulation of microtubule polymerization	GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION	0.344258046724248	1.17658374318251	0.227444466753062	0.677853854586713	29	TUBGCP5,CLASP1,TBCD,CLIP1,TUBGCP2,INPP5J,CAV3,CDKN1B,TUBGCP6,TUBGCP3,MAPRE1,CLASP2
GO:0070206	protein trimerization	GO_PROTEIN_TRIMERIZATION	-0.316989784351311	-1.16189168281848	0.227690667614267	0.677853854586713	34	MGST1,COL6A2,C1QTNF1,SKIL,ADIPOQ,MIF,SCARA5,NELL2,TRIM27,C1QTNF6,TRIM5,ALOX5AP,COL6A1,COL1A1,TRIM21,SKI,COL1A2,TRPM8
GO:0043113	receptor clustering	GO_RECEPTOR_CLUSTERING	0.313641080961103	1.16209593144602	0.227763728323699	0.677853854586713	41	SHANK3,MADCAM1,NRXN1,DLG4,MUSK,CDH2,DLG2,DNAJA3,GRIK5,ITGB2,ITGAL,GPHN
GO:0045995	regulation of embryonic development	GO_REGULATION_OF_EMBRYONIC_DEVELOPMENT	-0.242131641106488	-1.11792724366694	0.228344952726578	0.678983313496168	105	TBX18,SULF1,KDM1A,OSR1,TRAF3IP1,LAMA1,BMP4,WNT5A,LAMA3,SFRP2,WNT2B,GATA3,PTK7,OTX2,KLF4,CTNNB1,ADIPOQ,FZD3,STK3,E4F1,GDNF
GO:0051491	positive regulation of filopodium assembly	GO_POSITIVE_REGULATION_OF_FILOPODIUM_ASSEMBLY	-0.355417515757358	-1.17885721667142	0.228819139596137	0.679090495102893	23	NLGN1,AGRN,TGFBR1,GPM6A,CCL21,RHOQ,DPYSL3
GO:0006294	nucleotide excision repair preincision complex assembly	GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_ASSEMBLY	-0.338406981296243	-1.17159627867345	0.228903720346263	0.679090495102893	27	RPA3,CETN2,UBA52,RPA2,GTF2H2,DDB2,GTF2H1,XPC,UBB
GO:0046777	protein autophosphorylation	GO_PROTEIN_AUTOPHOSPHORYLATION	0.229188743965994	1.10621981717709	0.229583464553878	0.679090495102893	183	MARK2,PRKACA,CDKL5,MAPKAPK2,MKNK1,TNIK,CSNK2A1,FLT1,ULK1,LRRK2,PEAK1,CAMK2A,TAOK3,WNK1,EPHA1,MUSK,TAF1,WNK2,PINK1,PRKX,MAPKAPK3,SMG1,GSK3B,JAK2,DAPK2,CDK12,MAPKAPK5,CAMK2G,FGFR1,INSRR,AAK1,ERBB4,TYK2,MTOR,DAPK3,TEK,CAMK2B,ULK3,TRIM24
GO:0021761	limbic system development	GO_LIMBIC_SYSTEM_DEVELOPMENT	-0.245770355722105	-1.11899266230838	0.229713066160778	0.679090495102893	97	HAP1,SOX3,PHLPP2,DLX1,ANXA3,RARA,ID4,FGFR2,SEMA3A,LHX5,POU3F2,NR4A3,UBA6,LRP8,CASP3,CDK5,HTR5A,FGF13,LMX1A,KCNA1,BAX,SLC32A1,GSX1,BTG2
GO:0046660	female sex differentiation	GO_FEMALE_SEX_DIFFERENTIATION	-0.239505227289495	-1.11355224823159	0.229764196342637	0.679090495102893	110	LHX9,RBP4,TYRO3,AMHR2,BMP4,WNT5A,FGF7,CEBPB,FSHR,FANCF,SGPL1,BMPR1B,SLIT3,ROBO2,LEP,COL9A3,FAS,ADCYAP1,BAX,ACVR1B,AHR,AFP,FSHB,GPR149,FOXO3,INHBA,SIRT1,STRA6,FOXL2,MMP19,MMP14,BCL2,PLA2G4A
GO:0009214	cyclic nucleotide catabolic process	GO_CYCLIC_NUCLEOTIDE_CATABOLIC_PROCESS	0.402559651902916	1.19588865410967	0.229764915935129	0.679090495102893	17	PDE5A,PDE8B,PDE4C,PDE2A,PDE7A
GO:0001990	regulation of systemic arterial blood pressure by hormone	GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_HORMONE	-0.316384899926161	-1.1596745445467	0.230111491138453	0.679090495102893	34	CMA1,DRD5,CPA3,AVPR1B,TACR1,AGTR1
GO:0007613	memory	GO_MEMORY	0.259756685904593	1.12920912448888	0.230231549735496	0.679090495102893	92	CPEB3,SHANK3,CHAT,ITGA8,SLC24A2,DRD4,VLDLR,HRH2,SHANK1,MUSK,DRD2,RASGRF1,PTEN,GRIA1,EP300,PRKCZ,PAIP2,ADCY8,MTOR,CREB1,RGS14
GO:0007034	vacuolar transport	GO_VACUOLAR_TRANSPORT	0.223101282699346	1.10062539725709	0.230294699982001	0.679090495102893	217	EHD1,EHD4,TINAGL1,TRAK1,UBE2O,DENND5A,DENND3,KIF13A,ATG14,RAB6A,ALS2,ADRB2,VPS4A,RAB12,PCSK9,VPS13A,ERC1,VPS11,VPS13D,CHMP7,PIK3C3,DCLK1,VPS37B,FAM21C,PIKFYVE,RAB6B,KIF16B,VTI1A,ARL1,BET1L,VPS39,TGOLN2,RAB41,TBC1D10B,RAB9B,RASSF9,DCTN1,GNPTAB,NPC1,CDX2,GOSR1,CLTCL1,VPS37C,SORT1,GPRASP1
GO:0006401	rna catabolic process	GO_RNA_CATABOLIC_PROCESS	-0.215179038856896	-1.09359318729903	0.230398498338533	0.679090495102893	197	RPL24,RPL38,SMG9,RPL35,RPL30,RPL9,RPL3,RPS3A,RPS19,XRN2,RPS27,RPL4,CNOT6,RPS11,RPL7A,RPS4Y1,EIF4A2,RPS8,PABPC1,RPL18,EXOSC2,EXOSC6,RPS24,RPL18A,UBA52,RPL15,RPS16,PARN,RPL5,EXOSC5,RPL10A,RPS3,RPL22,RPS29,RPL26,RPL19,EXOSC10,RPS28,RPS5,RPS17,DROSHA,EXOSC8,RNASE2,POP1,PAPD5,RPL36,NANOS2,CNOT7,RPS6,RPL23A,RPS18,FAU,RPL32,RPLP0,RPL14
GO:0035315	hair cell differentiation	GO_HAIR_CELL_DIFFERENTIATION	-0.318619178297272	-1.15950157921878	0.231328398563893	0.680339832820165	33	PDZD7,LRTOMT,GRXCR1,ATP2B2,CTNNB1
GO:0036230	granulocyte activation	GO_GRANULOCYTE_ACTIVATION	-0.37601643716589	-1.184284088061	0.231417524653547	0.680339832820165	19	CCL3,ANXA3,STXBP3,VAMP8
GO:1901652	response to peptide	GO_RESPONSE_TO_PEPTIDE	-0.194959261359399	-1.07087900705996	0.23142873100983	0.680339832820165	380	ASS1,GNG8,SLC34A1,TIMP1,ATP6V1C2,SSTR3,KHK,GPR152,NKX6-1,LIPC,ALDOB,CYP11A1,AREG,SSTR4,RAB31,ATP6V1B1,SSTR2,PTPN2,RETN,CTGF,AVPR1B,BAIAP2L2,PRKCI,ANXA5,GCNT1,PKLR,ANXA1,SOCS1,AGTR1,KLF4,SESN2,XBP1,MEN1,ATP6V0D1,GNAI1,CTNNB1,F7,CAT,STAT3,ATP6V1H,IGFBP1,HCRTR2,ERRFI1,GNG12,NR4A3,RIPK2,STXBP3,NPFFR2,PRLH,ACVR1C,STAR,HIF1A,CPS1,BAIAP2,RAB13,RAB10,SCAP,ADIPOQ,PRKAR2B,LEP,RHOQ,PPARG,PCK1,SPARC,DENND4C,AP3S1,CCNA2,NAMPT,PRKAR1B,FAS,ADCY2,PRKACG,GNRHR,INPP5K
GO:1903650	negative regulation of cytoplasmic transport	GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT	0.251479577895894	1.12340507489368	0.231736393420127	0.680399349493187	108	PYDC2,LRRK2,CALM3,AKAP1,RANGAP1,SP100,SUFU,PKIA,GSK3B,SIAH3,SIRT4,CABP1,PLN,PDE2A,DERL3,CALM1,MTOR,INSIG1,YOD1,EMD,PARK7,BAG4,FAF1,MDFI,CD36,TRDN,TPR,LITAF,NFKBIA,FAM89B
GO:0044728	dna methylation or demethylation	GO_DNA_METHYLATION_OR_DEMETHYLATION	0.292614903297249	1.15026299274047	0.231853254268772	0.680399349493187	54	TET1,GNAS,PRMT7,TDRD5,ZFP57,EZH2,TET2,AICDA,CTCFL,PLD6,TDRKH,ATRX,FTO,BAZ2A,APOBEC1,GATAD2B
GO:0071542	dopaminergic neuron differentiation	GO_DOPAMINERGIC_NEURON_DIFFERENTIATION	-0.345283318186557	-1.17124410172282	0.232361407132342	0.681296599658068	25	WNT5A,FOXA1,OTX2,CTNNB1,HIF1A,RSPO2,LMX1A,PITX3,RAC1,NR4A2,LMX1B
GO:0010874	regulation of cholesterol efflux	GO_REGULATION_OF_CHOLESTEROL_EFFLUX	-0.381449971806687	-1.18457528964422	0.233048000866833	0.682715031260017	18	ADIPOQ,ABCA7,ABCA1,PLTP,NR1H3,ABCG1,LRP1,SIRT1,LAMTOR1
GO:0009187	cyclic nucleotide metabolic process	GO_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS	0.293521164512553	1.14969789196852	0.233712161824095	0.684065336260786	53	PDE5A,GUCY1A2,PDE8B,NUDT4,GUCY1B3,GUCY1A3,PDE4C,ADCY7,NPR2,ADCY5,PDE2A,GUCY2C,ADCY8,ADCY9,ADCY4,PDE7A
GO:0002377	immunoglobulin production	GO_IMMUNOGLOBULIN_PRODUCTION	-0.294848986346438	-1.14778725496041	0.23418845695528	0.684863897577301	44	GCNT3,TCF3,PMS2P1,TRAF3IP2,HLA-DRB5,EXOSC6,FAS,MSH3,POLQ,RNF8,POU2F2,HLA-DRB1,NBN,SWAP70,PMS2,VPREB1
GO:0018208	peptidyl proline modification	GO_PEPTIDYL_PROLINE_MODIFICATION	-0.299923179449737	-1.14882645403935	0.235786927109	0.687335423860845	41	FKBP11,PPIB,PPIL6,PPIL3,TTC9B,PPIH,PPIL4,TTC9,CRTAP,FKBP10,PPIE
GO:0009948	anterior posterior axis specification	GO_ANTERIOR_POSTERIOR_AXIS_SPECIFICATION	-0.289030563658518	-1.14187063099639	0.235927711929334	0.687335423860845	47	TBX6,WT1,BMP4,WNT5A,T,TMED2,OTX2,CTNNB1
GO:0003208	cardiac ventricle morphogenesis	GO_CARDIAC_VENTRICLE_MORPHOGENESIS	0.289097515045254	1.14505782725419	0.236013549652344	0.687335423860845	56	UBE4B,RYR2,HAND2,MYBPC3,BMP10,SMARCD3,PKP2,TNNI3,MYH7,DLL4,MYL2,TBX5,TBX20,NKX2-5,NPY5R,RXRA,TNNT2,HEY2,SMAD7,PROX1,MED1,MEF2C,DSP,PTCD2,TGFBR3
GO:0046386	deoxyribose phosphate catabolic process	GO_DEOXYRIBOSE_PHOSPHATE_CATABOLIC_PROCESS	-0.363598523152627	-1.17713750543018	0.236015626705079	0.687335423860845	21	MPG,NUDT18,DUT,SMUG1,NEIL2,NT5M
GO:0001658	branching involved in ureteric bud morphogenesis	GO_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS	-0.296338456198308	-1.14721562266302	0.236054590012816	0.687335423860845	43	WNT6,PAX8,WT1,BMP4,BMP2,NPNT,CTNNB1,GDNF,WNT9B,PKD2,MYC,DLG1,ADAMTS16,BCL2,FGF2
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL	-0.294288572220155	-1.14560567652048	0.23675157946804	0.688228405732449	44	CMA1,DRD5,CPA3,AVPR1B,SLC2A5,TACR1,AGTR1,ADRA1D,MME,TPM1
GO:2000515	negative regulation of cd4 positive alpha beta t cell activation	GO_NEGATIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.414675759115581	1.19155730683634	0.236770200189595	0.688228405732449	15	HLX,XCL1,IL4,HMGB1,BCL6,TNFSF4,JAK3,FOXP3,RC3H1
GO:0060045	positive regulation of cardiac muscle cell proliferation	GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION	0.386435255196078	1.18253721292177	0.237065451041435	0.688492069202304	19	TBX2,BMP10,FGFR1,ERBB4,TBX5,TBX20,CDK1,HEY2
GO:0042063	gliogenesis	GO_GLIOGENESIS	-0.222185566688249	-1.09719427899604	0.237270445565468	0.68849337911497	161	VTN,NAB2,CCL3,NKX6-1,MMP24,ID4,AREG,GAP43,KRAS,OLIG1,LPAR1,SOX11,TSPO,RTN4,CDKN2C,ANXA1,POU3F2,CTNNB1,STAT3,BOK,EMX1,ADAM22,SOX6,MPP5,CDK5,MXRA8,S100A9,HMBS,PICK1,SLC8A3,HDAC10
NA	er associated ubiquitin dependent protein catabolic process	GO_ER_ASSOCIATED_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS	0.288785321993493	1.14382129259399	0.237796398645035	0.688526265005534	56	FBXO6,ANKZF1,RNF121,EDEM2,PSMC6,SEL1L,PSMC5,KIAA0368,DERL3,TRIM13,DNAJB2,TMUB1,YOD1,VCP,NPLOC4
GO:0048709	oligodendrocyte differentiation	GO_OLIGODENDROCYTE_DIFFERENTIATION	-0.277778770882392	-1.13498892052957	0.237910013193212	0.688526265005534	55	VTN,NKX6-1,ID4,OLIG1,LPAR1,SOX11,CDKN2C,BOK,SOX6,CDK5,SLC8A3,HDAC10
GO:0006577	amino acid betaine metabolic process	GO_AMINO_ACID_BETAINE_METABOLIC_PROCESS	-0.379568310237683	-1.1787318764502	0.238118972803121	0.688526265005534	18	CHDH,SHMT1,ACADL,SLC22A4
GO:1900078	positive regulation of cellular response to insulin stimulus	GO_POSITIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS	0.380362068382285	1.18068380495236	0.238323464100666	0.688526265005534	20	PIK3R1,ESRRA,AKT2,PIK3R3,IRS1,PRKCZ,SERPINA12,MARCKS,PIK3R2
GO:0007050	cell cycle arrest	GO_CELL_CYCLE_ARREST	0.238152570217041	1.10931110730265	0.2386820161372	0.688526265005534	142	CUL4A,RRAGB,MFN2,RRAGD,ZAK,GAS2,AK1,TSC1,STRADA,IRF6,TSC2,PRKAB2,MACF1,ZFHX3,SOX2,PLAGL1,NKX3-1,CGREF1,PRKAA2,STRADB,MLF1,KHDRBS1,DST,IRF1,MTOR,CDKN1B,JMY,APC,GADD45A,TBRG4,CUL2,MCPH1,SMAD3,CUL5,MLST8,GAS2L2,FOXO4,PRKAG3,GAS2L3
GO:0046885	regulation of hormone biosynthetic process	GO_REGULATION_OF_HORMONE_BIOSYNTHETIC_PROCESS	-0.379303464710559	-1.17790941088409	0.238682414129375	0.688526265005534	18	KDM1A,FFAR3,BMP2,AKR1C3,HIF1A,BMP5
GO:1903046	meiotic cell cycle process	GO_MEIOTIC_CELL_CYCLE_PROCESS	0.241721420199486	1.11202865226654	0.238938652488274	0.688526265005534	130	TUBGCP5,NSUN2,SUN1,DMC1,LFNG,TUBGCP2,SYCP2,GOLGA2,SPANXA2-OT1,TEX11,SPIRE1,KLHDC3,RAD21L1,PRKAR1A,SMC1A,SPO11,SMC2,ERCC4,MLH3,TUBG1,NCAPD3,PLD6,CNTD1,TDRKH,HUS1,PRDM9,TUBGCP6,HFM1,CCNA1,BAG6,DMRTC2,TUBGCP3,MRE11A,UBE2B,UBR2,ESPL1,CCDC155,BRCA2,TOP2B,EREG,SPIRE2,RAD1,MLH1,PLK1,MEI1,TOP3A,NCAPD2,PPP2R1A,ASZ1,BRDT,DUSP13,ATM
GO:0008306	associative learning	GO_ASSOCIATIVE_LEARNING	0.278564744840781	1.13770954225046	0.239090957174844	0.688526265005534	65	NLGN3,DRD4,APP,ADRB2,NDRG4,HRH2,SHANK1,ATP1A2,DRD2,OPRK1,HMGCR,UCN,CLN8,NPS,NPTX2,MTOR,CREB1,RGS14
GO:1904666	regulation of ubiquitin protein ligase activity	GO_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY	0.406225425356466	1.18696429812269	0.239122758107983	0.688526265005534	16	PCID2,MAD2L1,GOLGA2,PTEN,GORASP1,TPR,PLK1,USP44
GO:0032925	regulation of activin receptor signaling pathway	GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY	-0.352046175753311	-1.16767507646329	0.239859525899912	0.690057405281286	23	DMRT1,ACVR1,MEN1,SMAD2,FGF9,MAGI2,ACVR2B,ACVR1B,NODAL
GO:2001026	regulation of endothelial cell chemotaxis	GO_REGULATION_OF_ENDOTHELIAL_CELL_CHEMOTAXIS	-0.385747427774887	-1.17973298908926	0.240147943072198	0.690297161725891	17	KDR,PRKD1,MET,FGF18,FGF4,THBS1,FGF2,FGF16
GO:0003281	ventricular septum development	GO_VENTRICULAR_SEPTUM_DEVELOPMENT	-0.280793298787769	-1.13360958017468	0.240469341065078	0.690631230396803	52	C5orf42,LRP2,WNT5A,GATA3,PTK7,FGFR2,CYR61,SOX11
GO:0010390	histone monoubiquitination	GO_HISTONE_MONOUBIQUITINATION	0.363698309263375	1.1726537872878	0.240972043642776	0.691254707714655	23	UHRF1,RNF40,PAF1,KDM2B
GO:0014047	glutamate secretion	GO_GLUTAMATE_SECRETION	-0.338631118221208	-1.16066452467369	0.241097155928997	0.691254707714655	26	SLC1A6,SNAP25,SLC1A1,SLC38A2,SLC17A7,UNC13B,STXBP1,GRM2,SYT1
GO:0043583	ear development	GO_EAR_DEVELOPMENT	-0.216050689027588	-1.08916679466097	0.241870689001743	0.692065259822269	186	RPL38,PAX8,NKX3-2,OSR1,PDZD7,RDH10,BMP4,WNT5A,MYO15A,ATP6V1B1,BMP2,DUOX2,NEUROG1,GATA3,LRTOMT,PTK7,FGFR2,GBX2,GRXCR1,OTX1,ATP2B2,DFNA5,USH1G,CEBPA,NR4A3,WDR19,HMX3,FZD3,PRKRA,SPARC,FGF9,CCNA2
GO:1901381	positive regulation of potassium ion transmembrane transport	GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT	0.354790732759546	1.16807849154534	0.241874805013672	0.692065259822269	25	ANK2,OPRK1,RNF207,KCNJ2,AKAP6,KCNH2
GO:0043470	regulation of carbohydrate catabolic process	GO_REGULATION_OF_CARBOHYDRATE_CATABOLIC_PROCESS	0.312268615032793	1.1505881332966	0.241996675820205	0.692065259822269	40	PPARA,PGAM2,PGAM1,HDAC4,PRKAA2,GCK,PPP1R3B,NCOR1,P2RX7,PPP1CB,HMGB1,PPP1R3E,PHKG2,DDIT4,CBFA2T3,PRKAG1,PPARGC1A,PGAM4,ENTPD5,OGT,INSR
GO:0043457	regulation of cellular respiration	GO_REGULATION_OF_CELLULAR_RESPIRATION	0.373483030472755	1.17549498238216	0.24313899193474	0.693248582971985	21	TRAP1,PRKACA,OPRK1,PINK1,PARK7,VCP,CBFA2T3,BNIP3,NOS2,PPARGC1A,PNPT1,PIK3CA,NOA1
GO:0060359	response to ammonium ion	GO_RESPONSE_TO_AMMONIUM_ION	-0.286115951722633	-1.13579964798528	0.243264552171562	0.693248582971985	48	ASS1,SLC34A1,AGRN,OPRM1,RGS8,HRH4,SLC18A2,CCNA2,CHRM4,ABL1,DIAPH1,GABRG2,GABRB2,HRH3
GO:0000291	nuclear transcribed mrna catabolic process exonucleolytic	GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_EXONUCLEOLYTIC	0.339874184510232	1.16160085153352	0.24337890375454	0.693248582971985	29	DCP2,EXOSC4,EXOSC7,LSM5,EDC3,LSM4,EXOSC3,DCP1A,CNOT8,PATL1,LSM6,DIS3L2,LSM1,POLR2G
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL	0.243290140115722	1.11170482437484	0.243427309782609	0.693248582971985	124	TRIP12,CDC26,PSMD11,N4BP1,PSMD2,PSMC6,CAPN3,MAD2L1,FZR1,SUFU,ANAPC1,PSMC5,PSMB7,LIMK1,UBR5,GTPBP4,DNAJB2,MTOR,ANAPC11,PARK7,CDK1,PSMD8,PSMB10,PIAS3,PSMD3,PSMB1,SMAD7,PSMA5,PSMB9,PRKCE,UBXN1
GO:1903312	negative regulation of mrna metabolic process	GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS	0.327983054208962	1.15626973735494	0.243440233236152	0.693248582971985	33	RNF40,C1QBP,ACIN1,SRSF4,SFSWAP,HNRNPA2B1,RNPS1,RBM42,RNF20,DYRK1A,DHX34,CCNT1,SRSF12
GO:0008033	trna processing	GO_TRNA_PROCESSING	0.252822011203803	1.11606583438531	0.243996754535881	0.693561767179358	101	NSUN2,CDK5RAP1,ZBTB8OS,ELAC2,ALKBH8,KIAA0391,CTU1,TARBP1,TRMT2B,TYW5,METTL1,CLP1,TRPT1,METTL2B,OSGEP,CPSF1,TRMT1L,TRMT1,DUS1L,LSM6,DUS4L,PUS1,URM1,RPP14,C2orf49,YRDC,PUS10,LCMT2,TRUB1,AARS2,OSGEPL1,WDR4,RPUSD3
GO:0035383	thioester metabolic process	GO_THIOESTER_METABOLIC_PROCESS	0.270772788094853	1.1270901973064	0.244230464555425	0.693561767179358	72	DLAT,AGK,ACOT6,ACSM2A,ACOT2,DLD,OGDH,PDHA1,MVD,ACOT11,ACSF2,SUCLG2,ELOVL6,PDHX,ACOT8,PDHB,ACACB,GCDH,DLST,PIPOX,MCEE,ACSS1,OXSM,ELOVL7
GO:0003338	metanephros morphogenesis	GO_METANEPHROS_MORPHOGENESIS	-0.330682677513545	-1.15533331433769	0.244654323984377	0.693561767179358	28	PAX8,WT1,BMP4,CTNNB1,WNT7B,GDNF,PKD2,FRAS1,FGF10,WNT4,KIF26B,SALL1,PDGFRB,CALB1,GREM1,SOX8,FMN1
GO:0001756	somitogenesis	GO_SOMITOGENESIS	-0.271965292860188	-1.12767858068796	0.245079234598347	0.693561767179358	59	SEMA3C,TBX6,WNT5A,SFRP2,T,TMED2,FOXF1,CRB2,COBL,PLXNA2,NLE1
GO:0051148	negative regulation of muscle cell differentiation	GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION	0.292536335510317	1.14130487241961	0.245188434338913	0.693561767179358	52	PPARD,PDGFB,CFLAR,ANKRD2,PRICKLE1,ZFHX3,HDAC4,CAV3,EZH2,MED28,SHH,ANKRD17,TNF,NKX2-5,SOX9,HEY2,FOXO4,TBX3,MSX1,GDF3,HDAC5,EREG,MYOCD,DKK1,CSRP3
GO:0019751	polyol metabolic process	GO_POLYOL_METABOLIC_PROCESS	0.25846836442536	1.1194891525498	0.245228295038122	0.693561767179358	90	PLCB2,MOGAT1,NUDT4,CALM3,PLCH1,INPP5J,INPPL1,PLCE1,IMPA2,PTEN,ITPK1,CYP27B1,INPP5D,ACER2,INPP1,PLCB4,IP6K3,CALM1,IP6K2,IPMK,PLCD3,GALK1,SGPP1,PLCG1,GOT1,PTAFR,ITPKC,CYP3A4,INPP5A,ITPKB,ITPKA,SCP2,MTMR2,COQ2
GO:0009127	purine nucleoside monophosphate biosynthetic process	GO_PURINE_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS	0.290821974618739	1.13912539054058	0.245648833136771	0.693561767179358	53	ATP5L,AK1,PPAT,ATP5A1,ATP5G2,ATP5D,AK4,ATP5O,ATP5B,ADA,ATP5G3,ADSSL1,ALDOA
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	-0.400145097920818	-1.17881434568877	0.245741618509621	0.693561767179358	15	PAX8,OSR1,GATA3,CTNNB1,ADIPOQ
GO:0007616	long term memory	GO_LONG_TERM_MEMORY	0.342448752341737	1.16036382496956	0.246027246959861	0.693561767179358	28	CPEB3,SHANK1,DRD2,RASGRF1,GRIA1,PRKCZ,ADCY8,MTOR,RGS14
GO:0002448	mast cell mediated immunity	GO_MAST_CELL_MEDIATED_IMMUNITY	-0.391275409367351	-1.17568414536087	0.246228110050436	0.693561767179358	16	MRGPRX2,NR4A3,SNAP23,LAT
GO:0070588	calcium ion transmembrane transport	GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT	-0.224012232476538	-1.09369071346982	0.246273077302794	0.693561767179358	149	SLC24A3,TRPM3,BBC3,CCL3,CACNG4,CCL19,TRPV5,TRPV3,GPM6A,RYR1,PKD1L3,STIM2,ANO6,ANXA5,OPRM1,TMEM37,ATP2B2,PKDREJ,GRIN2A,CCL21,CACNG3,CACNA1F,SLC25A25,CACNB1,ATP2B3,CALHM1,CACNA1I,ORAI1,TRPM6,RYR3,ITPR3,TMC2,SLC8A3,CACNG2,GRIN3B,ASPH,CACNB4,F2R,RASA3
GO:0045577	regulation of b cell differentiation	GO_REGULATION_OF_B_CELL_DIFFERENTIATION	0.372247257082774	1.1716055274384	0.246553346990754	0.693561767179358	21	BAD,PCID2,STAT5B,INPP5D
GO:0002686	negative regulation of leukocyte migration	GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MIGRATION	-0.337069834876535	-1.15531319665444	0.246662120845523	0.693561767179358	26	CCL28,HOXA7,CCL21,BMP5,MMP28,NOV,C5,PTGER4,HMOX1,CCL25,ADORA1,SLIT2,PADI2,CCL2
GO:0061462	protein localization to lysosome	GO_PROTEIN_LOCALIZATION_TO_LYSOSOME	-0.376830113822457	-1.17022853380658	0.246895655000542	0.693561767179358	18	AP3M1,SORL1,GCC2,SNX16,CD81,SH3BP4,HGS,GNPTG
GO:0045978	negative regulation of nucleoside metabolic process	GO_NEGATIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS	0.389297433268299	1.17450709788353	0.24713593404757	0.693561767179358	18	FLCN,PPARA,APOC3,PPIF,HDAC4
GO:0051568	histone h3 k4 methylation	GO_HISTONE_H3_K4_METHYLATION	0.353179766743918	1.16277470376366	0.24721513644455	0.693561767179358	25	WDR82,DYDC1,TET2,RBBP5,SETD1B,SETD3,HIST1H1D,PAXIP1,SETMAR,OGT
GO:0003231	cardiac ventricle development	GO_CARDIAC_VENTRICLE_DEVELOPMENT	0.253494140453436	1.11558495809888	0.247443162186442	0.693561767179358	99	UBE4B,SCN5A,RYR2,HAND2,MYBPC3,BMP10,NACA,XIRP2,SUFU,SMARCD3,DCTN5,NPRL3,PKP2,TNNI3,MYH7,EGLN1,TMEM65,DLL4,DAND5,LTBP1,MYL2,GJA5,TBX5,TBX20,LUZP1,NKX2-5,NPY5R,RXRA,TNNT2,WNT11,HEY2,SMAD7,PROX1,TBX3,MED1,MEF2C,DSP,PTCD2,TGFBR3
GO:0032233	positive regulation of actin filament bundle assembly	GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	-0.290351542512688	-1.13580004006517	0.247461214563959	0.693561767179358	45	ARHGEF5,S100A10,CTGF,LPAR1,ITGB1BP1,TACR1,EVL,TPM1,RAPGEF3,PPM1E,PFN3,ARHGEF15,RHOA
NA	regulation of sequence specific dna binding transcription factor activity	GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY	-0.196934918941474	-1.06743821959256	0.24763622451768	0.693561767179358	335	EDA2R,PTGIS,TCF3,TNFSF11,MAPK10,DAP,UFL1,NKX6-1,KDM1A,ARHGEF5,ANXA3,WWP2,PRKD1,WNT5A,TCEAL7,ANXA4,TAF6L,NEUROG1,KRAS,PRKCI,SGK1,FOXA1,ALK,TRAF5,RIPK4,BEX1,MID2,KLF4,CARD14,IRAK1,MEN1,WNT10B,CTNNB1,TRIM62,CAT,S100A12,PYCARD,PIM1,RIPK2,RIPK1,CHUK,MSX2,TRADD,LRP8,ZIC2,UBA52,RIPK3,MBTPS2,IRAK3,RHEBL1,STK3,CEBPG,TRIM38,RPS3,IKBKG,PPARG,KEAP1,S100A9,EIF2AK4,OPRD1,PSMD10,ZNF675,NLRP3,IL5,NLRP12,TLR9,CMKLR1
GO:0003151	outflow tract morphogenesis	GO_OUTFLOW_TRACT_MORPHOGENESIS	-0.276918062534992	-1.12724334553331	0.247671195528695	0.693561767179358	54	SEMA3C,RARA,WNT5A,SFRP2,RYR1,FGFR2,NPY2R,SOX11,PARVA,MSX2,HIF1A
GO:0072331	signal transduction by p53 class mediator	GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	-0.234544556085586	-1.10107679465922	0.248057151131921	0.694065146059888	116	EDA2R,SFN,FOXM1,PHLDA3,SNW1,NUPR1,MUC1,ZNF385C,CNOT6,TP73,BOK,PYCARD,CDKN1A,UBA52,ZMAT3,CCNB1,RPS27L,CHEK2,BAX,E2F4,WWOX,TRIAP1,BTG2,MDM2,MIF,FOXO3,UBB,IFI16,CNOT7,SIRT1,NBN,PCNA
GO:0030032	lamellipodium assembly	GO_LAMELLIPODIUM_ASSEMBLY	0.341806814054979	1.15818866164739	0.248459358142087	0.694613122513508	28	ABLIM1,NUP85,ABLIM3,ARHGEF6,SPATA13,CDH13,S1PR1,CCDC88A,ARHGEF4,VCL,GOLPH3,PARVB
GO:0040014	regulation of multicellular organism growth	GO_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH	0.277607404385877	1.12994326374665	0.248811522488292	0.694750625325253	64	GNAS,ADRB1,STAT5B,NPY1R,APP,ADRB2,CACNA2D2,DRD2,GHSR,CHD7,CELF1,GH1,STC2,CREB1,PTCH1,SOD1,MKKS,FXN,FTO,RAI1,FOXS1
GO:0045933	positive regulation of muscle contraction	GO_POSITIVE_REGULATION_OF_MUSCLE_CONTRACTION	-0.295037115659365	-1.13680559239606	0.248957445854446	0.694750625325253	42	NMU,CTGF,NPNT,NPY2R,TACR1,ADRA1D,PTGS1,F2R,HSP90AA1,ABAT,EDN1,PAWR,RGS2,ATP1A1
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	GO_NEGATIVE_REGULATION_OF_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY	-0.376156493058278	-1.16813663560022	0.249127749485318	0.694750625325253	18	PRAMEF4,CYP26B1,CYP26A1,CALR
GO:0099504	synaptic vesicle cycle	GO_SYNAPTIC_VESICLE_CYCLE	-0.250874552029063	-1.11127965843148	0.249754477856241	0.695921831510022	83	STX19,SYT4,SNAP25,NLGN1,SYTL1,SYT17,TRIM9,SNCA,CANX,RPH3A,C2CD4D,DDC,SLC17A7,SNAP23,PCLO,STX11,SYT6,SLC18A2,CDK5,UNC13B,SYT5,STX2
GO:0002762	negative regulation of myeloid leukocyte differentiation	GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	-0.298618998224012	-1.13713408596555	0.250212765957447	0.696254221693275	40	CCL3,RARA,PTPN2,HOXA7,CTNNB1,TJP2,ADIPOQ,ZNF675,CLDN18,CARTPT,MAFB,MYC,TRIB1,INHBA,GPR55,TLR3,LTF,CALCA,GPR68
GO:2000516	positive regulation of cd4 positive alpha beta t cell activation	GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	-0.332444677130765	-1.15095423001998	0.250798475737351	0.696254221693275	27	CD55,CCL19,RARA,ANXA1,RIPK2
GO:0002685	regulation of leukocyte migration	GO_REGULATION_OF_LEUKOCYTE_MIGRATION	-0.226161645811186	-1.09263805449521	0.250857506860055	0.696254221693275	139	CCL3,CCL28,CCL19,BDKRB1,WNT5A,CCR6,TNFSF14,HOXA7,ANO6,CALR,ANXA1,TACR1,CXCL1,F7,MIA3,PYCARD,CCL21,CSF1,RIPK3,BMP5,MMP28,C5AR1,NOV,RARRES2,C5,CMKLR1,THBS1,MSN,CCL4,PDGFD,PTGER4,THBS4,CXCL5,PAWR,SWAP70,PF4
GO:0032409	regulation of transporter activity	GO_REGULATION_OF_TRANSPORTER_ACTIVITY	0.228185597224878	1.09480690169226	0.250859905950383	0.696254221693275	175	SHANK3,AGT,NLGN3,PRKACA,OPRL1,ANK2,NRXN1,DLG4,DRD4,CALM3,CACNA2D1,RYR2,S100A1,SHANK1,WNK1,NEDD4L,ATP1A2,DRD2,HRC,RNF207,VAMP2,PPIF,PCSK9,WNK2,FXYD3,RASGRF1,AKAP6,CAV3,DMD,FXYD1,PLN,CALM1,AHNAK,GLRX,KLHL24,HAMP,KCNRG,PARK7,GRK6,HOMER1,ANK3,KCNIP2,CRHBP,PTAFR,HTT,FGF12,TRDN,SUMO1,JPH2,PRKCE
GO:0055012	ventricular cardiac muscle cell differentiation	GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	0.381794298061541	1.16833533966779	0.25090801274924	0.696254221693275	19	BMP10,NKX2-5,FHL2,RXRA,CDK1,HEY2,PROX1,MEF2C,RARB,MYOCD
GO:0048812	neuron projection morphogenesis	GO_NEURON_PROJECTION_MORPHOGENESIS	-0.193766374848909	-1.06289549429751	0.251879908650365	0.698375430409496	375	SEMA3F,NTNG1,LHX9,SEMA3C,LHX4,LRRN1,EZR,SLITRK2,PARD6B,KIF5A,EFNB3,GBX1,FLRT3,WNT5A,ULK2,GPM6A,FMOD,SLITRK4,GAP43,KRAS,GATA3,UNC5D,FGFR2,NEO1,EFNA5,S100A6,SGK1,GBX2,SEMA3A,LRFN4,SEMA3B,FLRT2,UNC5A,OTX2,PLXNB2,SPTBN4,EVL,COBL,BMPR1B,LRRC38,PLXNA2,BRSK2,SLIT3,FEZF1,ISL2,NR4A3,FLRT1,ROBO2,BAIAP2,ARTN,EPYC,RAB10,EMX1,CDH11,FZD3,USP33,CHRNB2,CDK5,CDH4,EXT1,PAK3,EIF2AK4,LMX1A,BOC,LINGO3,TLR9,CTNND2,STXBP1,DOCK7,SPTBN2,ATL1,NRCAM,LRFN3,NTN4,SEMA4A,SRGAP2,SLITRK5,PLXNA4,LLGL1,ECM2,POU4F2,SPTAN1,ISPD,UBB,PLXNB1,THBS4
GO:0010738	regulation of protein kinase a signaling	GO_REGULATION_OF_PROTEIN_KINASE_A_SIGNALING	0.394471599902898	1.17186138367919	0.252771165005208	0.699378499760181	17	AKAP3,LRRK2,AKAP1,AKAP6,AIP
GO:0006342	chromatin silencing	GO_CHROMATIN_SILENCING	0.268220521078711	1.11925644158066	0.252843610240518	0.699378499760181	73	HILS1,HIST1H2AB,HDAC2,DYDC1,SUV39H1,HIST1H3G,HIST1H3B,HELLS,SIRT4,HIST1H4F,SIRT5,RRP8,H2AFZ,H3F3A,MBD3L1,H2AFV,HIST1H3E,MSL3P1,BAZ2A,UBE2B,UBR2,HDAC5,HIST1H4A
GO:2000106	regulation of leukocyte apoptotic process	GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	-0.255263025152784	-1.1126117831089	0.252865013133732	0.699378499760181	76	NOC2L,BBC3,CCL19,BMP4,WNT5A,ANXA1,CCL21,NR4A3,SLC39A10,HIF1A,IRF7,RIPK3,HCAR2,LGALS16,RAG1,FAS,PRELID1,AURKB,BAX
GO:0050848	regulation of calcium mediated signaling	GO_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING	0.270908622663001	1.12181771262296	0.253332628015235	0.700015439068679	70	PRKACA,RCAN2,ITPR1,DRD4,LRRK2,CALM3,HRC,AKAP6,CD8A,DMD,PLN,CALM1,ADA,CDH13,GBP1,SLA2
GO:0042274	ribosomal small subunit biogenesis	GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS	-0.279461385078938	-1.12354411886084	0.253511235955056	0.700015439068679	51	RPL38,RPS19,RPS27,WDR46,RPS8,NOC4L,RPS24,RPS16,RPS27L,KRR1,RPS28,RPS5,RPS17,RPS6,NOP14,RPS15,RRP36,NOL11,RRS1
GO:0032095	regulation of response to food	GO_REGULATION_OF_RESPONSE_TO_FOOD	0.387052076850551	1.16773287636405	0.25424735874631	0.700968332747591	18	PPARA,GHSR,UCN,MTOR,NPY,MKKS,NPFF,GCG,MT3,BBS2
GO:0032092	positive regulation of protein binding	GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING	0.27012501378738	1.12142160592065	0.25427282658491	0.700968332747591	71	PLCL1,NRP1,EPB41,TIAM1,LRRK2,LFNG,MFNG,HIPK2,ADD1,GSK3B,RAPGEF2,CSF3,EP300,TMEM173,SPAG8,PARK7,TRIB3,BAMBI,PLXND1,FLOT1,MEF2C,GCG,MAPRE3,MAPRE1,TICAM1,STK4,HSP90AB1,SPPL3
GO:0043523	regulation of neuron apoptotic process	GO_REGULATION_OF_NEURON_APOPTOTIC_PROCESS	-0.215619127530772	-1.08194942641225	0.255372213125079	0.702466305164364	180	GDF5,BBC3,TYRO3,CCL3,DLX1,TOX3,MAP2K4,ANGPT1,KRAS,GATA3,CEBPB,PRKCI,SNCA,CLCF1,CTNNB1,NONO,TP73,NR4A3,STAR,HIF1A,CASP3,CDK5,C5AR1,GRID2,NQO1,PAK3,GDNF,KCNB1,XRCC2,STXBP1,MAP3K11,BAX,GRIK2,CPEB4,F2R,CLN3,ALKBH1,LRP1,BTG2,FOXO3,CDC42,NAE1,TRIM2,PAWR,PSEN1,GABRB2,MAP3K12,BCL2,UBE2V2,ISL1,HRAS,ITSN1
GO:0060039	pericardium development	GO_PERICARDIUM_DEVELOPMENT	-0.374122690077233	-1.16182075426999	0.256062411962293	0.702466305164364	18	WT1,FLRT3,WNT5A,BMP2
NA	jak stat cascade involved in growth hormone signaling pathway	GO_JAK_STAT_CASCADE_INVOLVED_IN_GROWTH_HORMONE_SIGNALING_PATHWAY	0.407587235207147	1.17118866393376	0.256082826818342	0.702466305164364	15	STAT5B,JAK2,GH1,MAPK1,JAK3,PRLR,MAPK3,PRL
GO:0070265	necrotic cell death	GO_NECROTIC_CELL_DEATH	-0.331026731916141	-1.14604517249861	0.256173043459107	0.702466305164364	27	PYGL,LY96,TMEM123,RIPK1,RIPK3,FAS,BAX
GO:0042771	intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator	GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE_BY_P53_CLASS_MEDIATOR	-0.327591456100133	-1.14453325940962	0.256261447139043	0.702466305164364	28	PHLDA3,SNW1,NUPR1,TP73,PYCARD,CDKN1A,RPS27L
GO:0002312	b cell activation involved in immune response	GO_B_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.327531927264739	1.14667311649172	0.25626923567227	0.702466305164364	32	ITFG2,LFNG,MFNG,HSPD1,ERCC1,ADA,AICDA,EXOSC3,RNF168,TLR4,MLH1,EXO1
GO:0019217	regulation of fatty acid metabolic process	GO_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS	0.267666989214246	1.11694661046695	0.25627707152164	0.702466305164364	73	AKT2,DLAT,PPARA,APOC3,DLD,GHSR,PRKAB2,PDHA1,LONP2,PRKAA2,SIRT4,IRS1,WDTC1,PDHX,MTOR,INSIG1,PDP1,PDHB,TRIB3,FABP3,PDPR,ACACB,ACADVL
GO:0048384	retinoic acid receptor signaling pathway	GO_RETINOIC_ACID_RECEPTOR_SIGNALING_PATHWAY	-0.396359462588051	-1.16766198805401	0.256585070233535	0.702634378906364	15	RARA,CYP26B1,SNW1
GO:0015695	organic cation transport	GO_ORGANIC_CATION_TRANSPORT	-0.373875907241867	-1.16105438155984	0.25675587820999	0.702634378906364	18	SLC22A4,SLC22A3,SLC7A8,SLC22A14,RHCE,SLC47A1,OAZ3
GO:0006814	sodium ion transport	GO_SODIUM_ION_TRANSPORT	-0.229068247690049	-1.09155563869337	0.257230724170755	0.702883185931631	128	SCN4A,SLC34A1,SLC24A3,SCNN1A,SCN3B,SLC5A9,SLC9A7,SLC22A4,ANO6,SLC10A1,SLC4A4,SGK1,SLC38A2,ABCB11,SLC17A2,SLC17A7,SLC5A2,KCNK1,SCNN1G,SLC38A1,SCNN1B,SLC13A5,SLC9B2,SLC38A8,SLC8A3,ATP4B,PKD2,SHROOM2,SLC9A3,SLC3A2,SLC23A2,ATP4A,SLC17A6,SLC38A11,SLC13A4,SLC5A11,SLC20A1,ATP1B1,HCN2,ATP1A1
GO:0002274	myeloid leukocyte activation	GO_MYELOID_LEUKOCYTE_ACTIVATION	-0.243819022527033	-1.10243309600499	0.257300691706603	0.702883185931631	93	MRGPRX2,CCL3,ANXA3,SNCA,BATF3,S100A12,PYCARD,NR4A3,STXBP3,CSF1,SLC7A2,SNAP23,IRF4,TNFSF9,VAMP8,MT1G,LAT
GO:0001914	regulation of t cell mediated cytotoxicity	GO_REGULATION_OF_T_CELL_MEDIATED_CYTOTOXICITY	0.363543318881791	1.15796704185642	0.257480068494412	0.702883185931631	22	XCL1,CEACAM1,HLA-B,P2RX7,LILRB1,HLA-E,IL12RB1,PPP3CB,STX7,HLA-A
GO:2000403	positive regulation of lymphocyte migration	GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MIGRATION	-0.334212514032393	-1.14551967573756	0.257682071134769	0.702883185931631	26	CCL3,WNT5A,TNFSF14,PYCARD,CCL21
GO:0031145	anaphase promoting complex dependent catabolic process	GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS	0.267347548443947	1.11561361723279	0.258037820896574	0.703283647884912	73	CDC26,PSMD11,PSMD2,PSMC6,MAD2L1,FZR1,ANAPC1,PSMC5,PSMB7,PSME4,ANAPC11,PSMA8,CDK1,PSMD8,PSMB10,PSMD3,PSMB1,PSMA5,PSMB9,PSMD6,PSMB3,PSMB6,PSMD1,PLK1,PSME2,UBE2D1,UBE2S,ANAPC7,ANAPC2
GO:0015833	peptide transport	GO_PEPTIDE_TRANSPORT	-0.262765112943512	-1.1133556232168	0.258841216606916	0.703373403116893	66	SMPD3,UBE2Q1,ILDR2,ANXA1,STXBP3,PCLO,EIF2AK3,LEP,SLC18A2,SMAD2,ABCA1,GPR119,SLC30A8,GAL,ACVR2B,CARTPT,CYB5R4,EDN1
GO:1902692	regulation of neuroblast proliferation	GO_REGULATION_OF_NEUROBLAST_PROLIFERATION	0.342671192044974	1.15018005279375	0.258868560335513	0.703373403116893	27	LRRK2,DRD2,CTNNA1,SMARCD3,SHH,CX3CL1,VEGFA,PAX6
GO:0010876	lipid localization	GO_LIPID_LOCALIZATION	0.216145191271832	1.08167310680749	0.259255047838729	0.703373403116893	245	APOL3,SLC10A5,SLC25A17,PRELID2,PPARD,ABCA9,ABCA10,STAT5B,OSBPL7,SLC27A5,FITM2,ABCA2,SLCO3A1,DRD4,LRP6,PPARA,VPS4A,VLDLR,APOC3,LDLR,DRD2,CFHR4,CEACAM1,PRKAB2,LCAT,ABCA8,PLA2G5,ABCA4,CEL,ATP11A,PITPNA,SYT7,ABCC2,ABHD4,SLC10A4,RFT1,LBP,PRKAA2,FITM1,CLN8,APOL4,AGTR2,LIPG,GULP1,GOT2,TNF,SLC27A6,RXRA,P2RX7,SLC10A6,PCTP,FABP3,STARD4,NPC1,CETP,SLCO1B1,NMUR2,ABCB4,NCOA1,ATP8B1,ACACB,CD36,APOL1,APOL2,ATP9B,SPNS1
GO:0098742	cell cell adhesion via plasma membrane adhesion molecules	GO_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES	-0.222964384312245	-1.08720772608519	0.259414535500259	0.703373403116893	148	CLDN1,CDH7,DSC3,CLDN15,IGSF9,NLGN1,CD200,PCDHB10,PCDHB5,CLDN9,CLDN16,UMOD,CDH15,CLSTN3,ROBO2,CDH11,CDH3,GRID2,CDH8,CDH4,AMIGO2,MPZL2,PCDHB16,CDH1,CDHR5,CLDN18
GO:0006084	acetyl coa metabolic process	GO_ACETYL_COA_METABOLIC_PROCESS	0.357754731660295	1.1534902151491	0.260203519341685	0.703373403116893	23	DLAT,DLD,PDHA1,MVD,PDHX,PDHB,ACACB,DLST,PIPOX,ACSS1,ACSS2,ACOT12,KYNU,PMVK
GO:0030518	intracellular steroid hormone receptor signaling pathway	GO_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	0.27657278462113	1.12202691055135	0.26024996459425	0.703373403116893	63	ESR1,RNF14,NKX3-1,JAK2,MED24,MED12,UBR5,AR,MED17,RHOXF1,ESR2,THRAP3,FHL2,NCOA3,TRIP4,NCOA1,DDX54,NR3C1,MED1
GO:0048753	pigment granule organization	GO_PIGMENT_GRANULE_ORGANIZATION	-0.366768247711239	-1.15515641561916	0.260328424345106	0.703373403116893	19	PMEL,RAB38,GPR143,SHROOM2,SNAPIN,BCL2,BLOC1S3,AP1M1,ASIP
GO:0032467	positive regulation of cytokinesis	GO_POSITIVE_REGULATION_OF_CYTOKINESIS	-0.317321342257567	-1.13662329140517	0.2603668261563	0.703373403116893	31	MRGPRX2,RXFP3,CSPP1,OPN1LW,OR1A2,AURKB,AURKC,RHOA,CDC42,CDC6,SPAST
GO:0009084	glutamine family amino acid biosynthetic process	GO_GLUTAMINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS	-0.36665322612209	-1.15479414890859	0.260806290455711	0.703373403116893	19	ASS1,PYCR1,CPS1,OAT,LGSN,PYCR2,NOXRED1
NA	regulation of mrna 3 end processing	GO_REGULATION_OF_MRNA_3_END_PROCESSING	0.345803975327217	1.14987219346048	0.260822530666129	0.703373403116893	26	CPEB3,RNF40,PAF1,NCBP1,TNRC6C,TNRC6B,NCBP2
GO:0007218	neuropeptide signaling pathway	GO_NEUROPEPTIDE_SIGNALING_PATHWAY	-0.243258415199536	-1.09989829759061	0.261148752331264	0.703373403116893	93	NMU,SORCS3,SCG5,NXPH2,NMB,SSTR2,LTB4R,RXFP3,NPY2R,OPRM1,PCSK1N,HCRTR2,GPR143,NPFFR2,GLRA4,NPBWR1,POMC,OPRD1,ADCYAP1,GAL,CARTPT,HCRT,GPR149
GO:0002688	regulation of leukocyte chemotaxis	GO_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS	-0.245614808060823	-1.10191993828683	0.261305114638448	0.703373403116893	89	CCL3,CCL19,WNT5A,CCR6,TNFSF14,ANO6,CALR,CXCL1,F7,CCL21,CSF1,MMP28,C5AR1,NOV,RARRES2,C5,CMKLR1,THBS1,CCL4,THBS4,CXCL5,SWAP70,PF4
GO:0036150	phosphatidylserine acyl chain remodeling	GO_PHOSPHATIDYLSERINE_ACYL_CHAIN_REMODELING	-0.385976303127758	-1.15976166456775	0.26140225555772	0.703373403116893	16	PLA2G2A,PLA2G16,PLA2G2D,PLA2G4F,LPCAT3,PLA2G2F,PLA2G4A
NA	maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 	GO_MATURATION_OF_5_8S_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_	0.384465535452693	1.15992930261519	0.2614701895761	0.703373403116893	18	NOL9,WDR12,ABT1,EXOSC7,EXOSC3,FTSJ3
GO:0019068	virion assembly	GO_VIRION_ASSEMBLY	0.331813529040487	1.1435882157802	0.261787935720409	0.703373403116893	30	LRSAM1,VPS4A,RAB1B,CHMP7,VPS37B,MITD1,VPS37C,CHMP6,TSG101,VPS37A,CHMP1B,CHMP4B,CHMP4C
GO:0042303	molting cycle	GO_MOLTING_CYCLE	-0.249836232967471	-1.10239322234143	0.261848175590661	0.703373403116893	81	DNASE1L2,KRT71,FGF7,FGFR2,KRTAP4-9,KRT25,EDAR,CTNNB1,EGFR,TMEM79,CDH3,FZD3,SNRPE,KRT14,MPZL3,KRT16,ACVR1B,KRTAP4-8,CDC42,KRT33B,INHBA,SOX21
GO:0045132	meiotic chromosome segregation	GO_MEIOTIC_CHROMOSOME_SEGREGATION	0.291502198860529	1.12757826206307	0.261911601019712	0.703373403116893	50	SUN1,DMC1,SYCP2,TEX11,RAD21L1,SPO11,SMC2,ERCC4,MLH3,HFM1,BAG6,MRE11A,UBE2B,ESPL1,CCDC155,BRCA2,TOP2B,MLH1,PLK1,MEI1,PPP2R1A,ATM,MAEL
NA	hydrogen transport	GO_HYDROGEN_TRANSPORT	0.240227569861661	1.09926572572659	0.261929812652729	0.703373403116893	125	COX15,ATP5L,SLC2A12,UQCRHL,COX6A1,NNT,UQCRFS1,ATP1A2,MFSD3,UQCRC1,ATP5A1,ATP5G2,ATP5D,COX10,ATP5O,ATP6V0E2,ATP5B,SLC4A10,COX4I1,ATP5G3,COX11,ADHFE1,SLC15A1,ATP6V0D2,COX7A2,COX6A2,SLC9A8,COX7B,COX7A1,ATP6AP1,COX5A,ATP1A3,NDUFA4,UQCRQ,SLC9A6
GO:0033865	nucleoside bisphosphate metabolic process	GO_NUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS	0.318363045657887	1.13749702886818	0.262425013633885	0.703373403116893	35	PANK3,SULT1A2,MCCC2,HMGCR,COASY,SULT1C4
GO:0050772	positive regulation of axonogenesis	GO_POSITIVE_REGULATION_OF_AXONOGENESIS	0.272923579083869	1.11809987038601	0.262546902249546	0.703373403116893	66	CDKL5,NRP1,LPAR3,PAFAH1B1,TIAM1,TRPV2,MEGF8,ZEB2,MACF1,GSK3B,GOLGA4,LIMK1,EP300,SEMA5A,VEGFA,L1CAM,BCL11A,NTRK3,PLXNB3,SRF
GO:0090559	regulation of membrane permeability	GO_REGULATION_OF_MEMBRANE_PERMEABILITY	0.273962054225035	1.11891130905496	0.262751458946737	0.703373403116893	65	RHOT2,BAD,DYNLL2,ATPIF1,MOAP1,CAMK2A,GZMB,PPIF,GSK3B,LBP,NMT1,PPP3R1,PPP1R13B,MTOR,ATF2,TMEM102,BID,MAPK8,YWHAG,BAK1,TP53BP2,MT3,BMF,BNIP3
GO:0042558	pteridine containing compound metabolic process	GO_PTERIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.316806648825466	-1.1347796948204	0.262980684033316	0.703373403116893	31	SHMT1,ALDH1L1,GART,MTHFD1L,PTS,TYMS,DHFR,FTCD,ALDH1L2
GO:0042490	mechanoreceptor differentiation	GO_MECHANORECEPTOR_DIFFERENTIATION	-0.28205821656872	-1.11969158364394	0.263178050099117	0.703373403116893	48	PDZD7,BMP4,LRTOMT,GRXCR1,ATP2B2,DFNA5,USH1G
GO:0021953	central nervous system neuron differentiation	GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION	-0.219716871890231	-1.08263840029341	0.263187987868543	0.703373403116893	159	PAX7,LHX4,DLX1,NKX6-1,GBX1,GDPD5,ID4,WNT5A,SPOCK1,UNC5D,FGFR2,CEND1,HOXC10,GBX2,SEMA3A,OLIG3,LHX5,MDGA2,SPTBN4,ATP2B2,SLIT3,EVX1,ISL2,MDGA1,ROBO2,EMX1,CDH11,LEP,CHRNB2,CDK5,GRID2,LMX1A,ZC4H2
GO:0070528	protein kinase c signaling	GO_PROTEIN_KINASE_C_SIGNALING	0.405098852707031	1.16403837775224	0.263294856781725	0.703373403116893	15	PDGFB,DGKQ,PRKCH,PRKCZ,ZP3,FLOT1
GO:0097061	dendritic spine organization	GO_DENDRITIC_SPINE_ORGANIZATION	0.390519081901985	1.16011959234438	0.264134801368844	0.705057685493679	17	SHANK3,DLG4,SHANK1,ARF1,PTEN,TANC1,ITPKA,MTMR2
GO:0046337	phosphatidylethanolamine metabolic process	GO_PHOSPHATIDYLETHANOLAMINE_METABOLIC_PROCESS	-0.393449975403934	-1.15909073415372	0.264398415687293	0.705202113473398	15	HRASLS5,LIPC,ALOX15
GO:0001977	renal system process involved in regulation of blood volume	GO_RENAL_SYSTEM_PROCESS_INVOLVED_IN_REGULATION_OF_BLOOD_VOLUME	0.390154234899254	1.15903573709712	0.265046124088677	0.706134971403789	17	PDGFB,HSD11B2,GJA1,GJA5,CYBA,EMP2,UTS2,CYP4F12
GO:0033013	tetrapyrrole metabolic process	GO_TETRAPYRROLE_METABOLIC_PROCESS	0.284567372729117	1.12286209645905	0.265167737330478	0.706134971403789	55	COX15,CUBN,ATPIF1,MMAA,MTR,ABCC1,COX10,MMACHC,CTRC,ALAD,FXN,HMOX2,EIF2AK1,CYP1A1,PRSS3,NFE2L1,MUT,SLC25A38,RSAD1,FECH,PRSS1
GO:0010634	positive regulation of epithelial cell migration	GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	-0.241069745597903	-1.09537861192262	0.266070708747303	0.707782210385877	96	PRKCA,ITGA3,ANXA3,KDR,PRKD1,BMP4,WNT5A,MET,CCR6,FGF7,ANGPT1,GATA3,ITGB1BP1,TACR1,SRPX2,INSL3,FGF18,ANGPT4,HIF1A
GO:1904888	cranial skeletal system development	GO_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT	-0.27239756100904	-1.11300159023108	0.266525635776352	0.707782210385877	55	IRX5,RDH10,TGFBR1,BMP4,GRHL2,FGFR2,MTHFD1L,CTNNB1,WDR19,MSX2,FGF4,SMAD2,SPEF2,WNT9B,TULP3,NODAL,SLC39A1
GO:0006081	cellular aldehyde metabolic process	GO_CELLULAR_ALDEHYDE_METABOLIC_PROCESS	0.26246624762885	1.10876665415582	0.266567399491986	0.707782210385877	78	DLAT,NDUFAB1,DDO,AMT,ALDH7A1,HAGH,DLD,LIPT2,RPIA,ADH5,OGDH,RPE65,DHTKD1,PDHA1,LIAS,IDH2,PDHX,PARK7,PDHB,IDH1,HOGA1,DBT,DLST,AKR7A2,GLO1,GPI,TKT,ADH4
GO:0001504	neurotransmitter uptake	GO_NEUROTRANSMITTER_UPTAKE	-0.39249175015254	-1.15626783396423	0.267103867714218	0.707782210385877	15	SNAP25,SNCA,SLC18A1,SLC22A3,SLC6A3,SLC38A1
GO:0046782	regulation of viral transcription	GO_REGULATION_OF_VIRAL_TRANSCRIPTION	-0.272248503422148	-1.11239254905379	0.26745825940585	0.707782210385877	55	CCL3,TARBP2,POLR2H,SNW1,TRIM11,MDFIC,MID2,TRIM62,POLR2K
NA	v d j recombination	GO_V_D_J_RECOMBINATION	-0.392345357990302	-1.15583656745156	0.267601670887172	0.707782210385877	15	TCF3,RAG2,RAG1,HMGB2
GO:0022612	gland morphogenesis	GO_GLAND_MORPHOGENESIS	-0.241414030465948	-1.09502234246495	0.267621301775148	0.707782210385877	95	SEMA3C,EZR,ID4,AREG,BMP4,WNT5A,FGF7,DUOX2,CEBPB,FGFR2,FOXA1,CRIP1,SEMA3A,EDAR,CSF1,EGFR,MSX2,NKX2-3,RPS6KA1,CAPN1,BSX,EPHA2,MSN
GO:0072595	maintenance of protein localization in organelle	GO_MAINTENANCE_OF_PROTEIN_LOCALIZATION_IN_ORGANELLE	-0.328170814987429	-1.13615772386187	0.267737174827639	0.707782210385877	27	MORC3,KDELR3,ARL2BP,TSPO,KDELR2,HK2
GO:1903793	positive regulation of anion transport	GO_POSITIVE_REGULATION_OF_ANION_TRANSPORT	-0.270973043228048	-1.11096484861606	0.267990526507561	0.707782210385877	56	CFTR,SLC34A1,TNFSF11,NPY2R,SLC18A1,RAB3B,ABCA7,CHRNB2,VAMP8,GDNF,PRELID1,CYP4F2,TRIAP1,ABAT,MIF,EDN1
GO:0009755	hormone mediated signaling pathway	GO_HORMONE_MEDIATED_SIGNALING_PATHWAY	0.232907507964194	1.09034522190323	0.268726844055237	0.707782210385877	147	NR1I2,NR3C2,PPARD,ESRRA,STAT5B,CSNK2B,NR2F6,PPARA,ESR1,GHSR,RNF14,ABHD2,NKX3-1,JAK2,MED24,ADIPOR2,MED12,RXRB,UBR5,LATS1,AR,RXRG,MED17,RHOXF1,ESR2,THRAP3,FHL2,RXRA,NCOA3,ESRRG,TRIP4,CRHBP,NCOA1,NR2F1,PTH,DDX54
GO:0045622	regulation of t helper cell differentiation	GO_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION	-0.331239021756732	-1.13532797505488	0.268790005059059	0.707782210385877	26	CCL19,RARA,IL27,ANXA1,RIPK2,IRF4,NLRP3
GO:0048863	stem cell differentiation	GO_STEM_CELL_DIFFERENTIATION	-0.213409278649025	-1.07502423627841	0.26884732843694	0.707782210385877	185	SEMA3F,SEMA3C,OSR1,RDH10,TGFBR1,BCHE,BMP4,WNT5A,CUL7,BMP2,GPM6A,T,HOXA7,FGFR2,ADAM15,FOXA1,SOX11,RTN4,GBX2,SEMA3A,SEMA3B,ACVR1
GO:0070979	protein k11 linked ubiquitination	GO_PROTEIN_K11_LINKED_UBIQUITINATION	0.3400741550968	1.14146306647128	0.268868010915151	0.707782210385877	27	CDC26,UBE2T,FZR1,ANAPC1,ANAPC11,UBE2B,UBE2H,UBE2D4,RNF4,UBE2S,ANAPC7,ANAPC2,ANAPC13,UBE2D3
GO:0010259	multicellular organism aging	GO_MULTICELLULAR_ORGANISM_AGING	-0.324263306336114	-1.13290542838324	0.268949842222565	0.707782210385877	28	BBC3,SEC63,HELT,CISD2,DDC,SERP1,SPEF2
GO:0046716	muscle cell cellular homeostasis	GO_MUSCLE_CELL_CELLULAR_HOMEOSTASIS	0.395600798882085	1.15591982990676	0.269231484062819	0.707782210385877	16	CAPN3,CAV3,DMD,PFKM,TRIM32,ALDOA,SOD1,CFL2,SRF
GO:0033762	response to glucagon	GO_RESPONSE_TO_GLUCAGON	0.299285010778562	1.12663212708278	0.26930211616389	0.707782210385877	44	GNAS,PRKACA,GNG2,GLP1R,ADCY7,PRKAR1A,ADCY5,GNB3,GNG11,ADCY8,ADCY9,CREB1,HMGCS2,CYC1,ADCY4
GO:0046655	folic acid metabolic process	GO_FOLIC_ACID_METABOLIC_PROCESS	-0.391637385022275	-1.15375090228808	0.269506309114127	0.707782210385877	15	SHMT1,ALDH1L1,MTHFD1L,DHFR,ALDH1L2
GO:0072176	nephric duct development	GO_NEPHRIC_DUCT_DEVELOPMENT	-0.391617930410847	-1.15369358964034	0.269571239962773	0.707782210385877	15	OSR1,BMP4,GATA3,WNT9B,PKD2
GO:0051150	regulation of smooth muscle cell differentiation	GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_DIFFERENTIATION	0.375739321086726	1.14980639982644	0.269976280483285	0.707901936881256	19	ZEB1,PDGFB,SMARCD3,MED28,SHH,ANKRD17,HEY2,FOXO4,SRF,CTH,EREG,MYOCD
GO:0030318	melanocyte differentiation	GO_MELANOCYTE_DIFFERENTIATION	0.381763342384173	1.1517768087439	0.270215570863583	0.707901936881256	18	MREG,C10orf11,USP13,MITF,TYRP1,MEF2C
GO:0032729	positive regulation of interferon gamma production	GO_POSITIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION	-0.26850685120192	-1.10917121389443	0.27028322340644	0.707901936881256	58	IL18,WNT5A,IL27,PYCARD,RIPK2,TNFSF9,CEBPG,TLR9,IFNAR1,TXK,ABL1,CD276,ISL1,HRAS,PDE4B,TLR3,TNFRSF13C
GO:0031062	positive regulation of histone methylation	GO_POSITIVE_REGULATION_OF_HISTONE_METHYLATION	0.335778682834263	1.13776275747091	0.27045807808357	0.707901936881256	28	TET1,JARID2,ZNF304,PAF1,EED
GO:0000301	retrograde transport vesicle recycling within golgi	GO_RETROGRADE_TRANSPORT_VESICLE_RECYCLING_WITHIN_GOLGI	-0.374742878692701	-1.14607773011011	0.271899467924039	0.710166346417133	17	RGPD3,SORL1,GCC2,COG1,GOLGA5
GO:0006283	transcription coupled nucleotide excision repair	GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR	0.269947538891792	1.10909206009777	0.272485561346669	0.710166346417133	67	CUL4A,COPS6,COPS7A,ERCC1,GTF2H3,LIG3,EP300,COPS7B,POLD2,ERCC4,POLR2I,XAB2,RFC3,AQR,PRPF19,HMGN1,GTF2H5
GO:0007215	glutamate receptor signaling pathway	GO_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY	-0.295010949990837	-1.11706088367131	0.272977570846577	0.710166346417133	39	GRIA4,GRID1,HOMER3,GRIA2,GRIN2A,GRID2,KCNB1,GRIN2D,GRIN3B,GRIK2,CPEB4,CLN3,GRM2,GRM6,GRM8,GRM3,PTK2B
GO:0043491	protein kinase b signaling	GO_PROTEIN_KINASE_B_SIGNALING	0.317909209680947	1.12858955700742	0.273010040745052	0.710166346417133	34	PIK3C2B,AKT2,TSC2,NKX3-1,PTEN,CD40,EP300,SETX,TNF,SOX9
GO:0051354	negative regulation of oxidoreductase activity	GO_NEGATIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY	0.34573822892966	1.13827490863866	0.273164375768476	0.710166346417133	25	LRRK2,OXA1L,TMLHE,DAOA,GSK3B,CAV3,CYP27B1,NOSIP,HDAC6,ENG,NFKB1
GO:0098813	nuclear chromosome segregation	GO_NUCLEAR_CHROMOSOME_SEGREGATION	0.221756487222007	1.07972172101535	0.273195535891171	0.710166346417133	196	GSG2,NDE1,SPAG5,CENPK,FBXW7,POGZ,SUN1,CLASP1,CENPA,PAFAH1B1,AKAP8,VPS4A,DMC1,RANGAP1,NCAPH,CLIP1,NUP85,MAD2L1,SYCP2,TEX11,CHMP7,RAD21L1,TTN,SMC1A,LATS1,SPO11,FAM83D,SMC2,ERCC4,MAU2,MLH3,KIFC1,INCENP,CENPN,NAA50,NCAPD3,DLGAP5,HFM1,KIF25,CEP57L1,BAG6,CENPI,CHMP6,KLHL22,ZWILCH,MAD1L1,MRE11A,CKAP5,UBE2B,ESPL1,CCDC155,AKAP8L,DIS3L2,BRCA2,TOP2B,MAPRE1,CHMP1B,PAPD7,CLASP2,PHF13,KPNB1,CENPO,CHMP4B,CENPT,MLH1,SKA2,PLK1
GO:1901699	cellular response to nitrogen compound	GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND	-0.187506659032219	-1.04922315980538	0.273324268811294	0.710166346417133	463	ASS1,CFTR,GNG8,SLC34A1,ATP6V1C2,EZR,SSTR3,DRD5,SHMT1,TARBP2,GPR152,NKX6-1,AGRN,WT1,ALDOB,COLEC12,AQP1,CYP11A1,SSTR4,RAB31,ATP6V1B1,RYR1,SSTR2,PTPN2,APLP1,BAIAP2L2,CEBPB,GPD1,PRKCI,AQP8,ANXA5,MB21D1,PKLR,SNCA,OPRM1,SOCS1,IPO5,AGTR1,KLF4,XBP1,MEN1,WNT10B,ATP6V0D1,CTNNB1,STAT3,ATP6V1H,IGFBP1,ERRFI1,GNG12,DDC,NR4A3,RIPK2,EGFR,STAR,HIF1A,CPS1,BAIAP2,HTR1B,RAB13,RAB10,RGS8,ADIPOQ,HRH4,PRKAR2B,SLC18A2,PRKRA,SMAD2,RHOQ,PPARG,DENND4C,AP3S1,RAPGEF3,CCNA2,NAMPT,RYR3,PRKAR1B,ITPR3,FAS,HMBS,CDH1,CHRM4,ADCY2,PRKACG,GNRHR,INPP5K,CAPN2,SLC8A3,NOD1,KLF6,ATP6V1A,RRAGC,PDPK1,CPEB4
NA	mrna transcription from rna polymerase ii promoter	GO_MRNA_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER	-0.39005300770062	-1.14908337861865	0.273683527043698	0.710166346417133	15	LMO2,HIF1A,C5AR1,ZBTB1
GO:2000116	regulation of cysteine type endopeptidase activity	GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY	-0.209845470854744	-1.07034596112385	0.273884377466079	0.710166346417133	202	BBC3,P2RX1,SFN,DAP,IFT57,AQP1,SFRP2,CTGF,TNFSF14,WNT9A,CYR61,CYCS,SNCA,KLF4,BOK,PYCARD,BCAP31,RIPK1,NLE1,ACVR1C,TRADD,EIF2AK3,PLAUR,CASP3,MAGEA3,RPS27L,RPS3,PPARG,S100A9,SH3RF1,DAPK1,RAG1,ARL6IP5,FAS,HGF,NLRP3,NLRP12,RPS6KA1,FABP1,THBS1,BAX,NOD1,ASPH,F2R,TRIAP1,NEK5,NODAL,MDM2,SENP1,MYC,IFI16,IFI6,F3,SIRT1,PAWR,RET,FOXL2,TNFAIP8
GO:0045143	homologous chromosome segregation	GO_HOMOLOGOUS_CHROMOSOME_SEGREGATION	0.308552583026706	1.12454012681733	0.274491381490984	0.710166346417133	38	SUN1,DMC1,SYCP2,TEX11,RAD21L1,SPO11,MLH3,BAG6,MRE11A,UBE2B,ESPL1,CCDC155,BRCA2,MLH1,PLK1,MEI1,ATM,MAEL
GO:0002076	osteoblast development	GO_OSTEOBLAST_DEVELOPMENT	0.387103112084866	1.14997173095847	0.274512721321232	0.710166346417133	17	LRP5,ESR1,GLI2,HDAC4,SHH,LIMD1,SMAD3,PTH1R
GO:0010001	glial cell differentiation	GO_GLIAL_CELL_DIFFERENTIATION	-0.227318298932657	-1.08157586122908	0.274519865122416	0.710166346417133	127	VTN,NAB2,NKX6-1,MMP24,ID4,GAP43,KRAS,OLIG1,LPAR1,SOX11,CDKN2C,POU3F2,CTNNB1,STAT3,BOK,EMX1,ADAM22,SOX6,MPP5,CDK5,MXRA8,S100A9,HMBS,PICK1,SLC8A3,HDAC10
GO:1900117	regulation of execution phase of apoptosis	GO_REGULATION_OF_EXECUTION_PHASE_OF_APOPTOSIS	-0.346357793980992	-1.13551711740798	0.274605502177672	0.710166346417133	22	PTGIS,FAP,CIDEA,BOK,FZD3,RPS3,BAX
GO:0021695	cerebellar cortex development	GO_CEREBELLAR_CORTEX_DEVELOPMENT	0.296819481179683	1.12268334812287	0.274702739652102	0.710166346417133	45	HERC1,ATP7A,NRXN1,GLI2,RERE,OGDH,CLP1,AGTR2,EZH2,CBLN1,LDB1,LHX1,UQCRQ,PROX1,TRNP1,SMO,KLHL1,AGTPBP1
GO:0001823	mesonephros development	GO_MESONEPHROS_DEVELOPMENT	-0.243772469356637	-1.09365451745472	0.274873603762493	0.710166346417133	89	WNT6,PAX8,OSR1,RARA,WT1,BMP4,BMP2,NPNT,GATA3,FGFR2,SDC1,SIM1,CTNNB1,CAT
GO:0046365	monosaccharide catabolic process	GO_MONOSACCHARIDE_CATABOLIC_PROCESS	0.283823141296504	1.11570276236093	0.274898192469815	0.710166346417133	54	LRP5,BAD,PGM5,CRYL1,PGAM2,PGAM1,FUT5,PFKM,GCK,PFKFB4,PFKP,ALDOC,FUT4,ALDOA,HK3,ENO2,GALK1
GO:0048169	regulation of long term neuronal synaptic plasticity	GO_REGULATION_OF_LONG_TERM_NEURONAL_SYNAPTIC_PLASTICITY	0.353359268514895	1.13931814898037	0.274934792990706	0.710166346417133	23	SHANK3,AGT,DLG4,DRD2
GO:0016578	histone deubiquitination	GO_HISTONE_DEUBIQUITINATION	-0.356081142609055	-1.13787958230281	0.275357904355772	0.710166346417133	20	USP27X,USP49,ATXN7L3,TAF10,BRCC3,USP16
GO:1903313	positive regulation of mrna metabolic process	GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS	0.302209501104399	1.11973989695982	0.275487716763006	0.710166346417133	41	CPEB3,PAF1,SNRNP70,NCBP1,TNRC6C,SF3B4,TNRC6B,THRAP3,NCBP2,PRPF19,CNOT8,APOBEC1,CNOT1,POLR2G,ZFP36L2,RC3H1,DAZAP1,UPF1,PNPT1,NANOS3
GO:0006584	catecholamine metabolic process	GO_CATECHOLAMINE_METABOLIC_PROCESS	-0.300882346830806	-1.11836957545786	0.275553178688415	0.710166346417133	36	HDC,NPR1,SNCAIP,GATA3,LRTOMT,SNCA,GRIN2A,DDC,SLC6A3
GO:0036149	phosphatidylinositol acyl chain remodeling	GO_PHOSPHATIDYLINOSITOL_ACYL_CHAIN_REMODELING	-0.381307485732952	-1.14573304314855	0.275753836829231	0.710166346417133	16	PLA2G2A,PLA2G16,PLA2G2D,PLA2G4F
GO:0006040	amino sugar metabolic process	GO_AMINO_SUGAR_METABOLIC_PROCESS	-0.296549564573044	-1.11546077267293	0.276737728412755	0.71097849599978	38	CHI3L1,AMDHD2,GFPT2,UAP1,PGM3,EXTL2,SLC35A3,DPAGT1
NA	epithelial cilium movement	GO_EPITHELIAL_CILIUM_MOVEMENT	-0.388919570983008	-1.14574431119138	0.2770599311733	0.71097849599978	15	TTLL1,DNAH1,ADCY10,ROPN1L,LRRC6,DPCD,SPA17
GO:0042733	embryonic digit morphogenesis	GO_EMBRYONIC_DIGIT_MORPHOGENESIS	0.280142198378404	1.11321712743177	0.277111872146119	0.71097849599978	57	LRP5,GNA12,TBX2,HDAC2,C2CD3,CREBBP,GLI2,HAND2,OSR2,FBXW4,GJA1
GO:0002702	positive regulation of production of molecular mediator of immune response	GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	-0.266250721037917	-1.10398364456576	0.27720692332283	0.71097849599978	59	RBP4,FFAR3,WNT5A,KLK7,GATA3,MZB1,CLCF1,XBP1,NR4A3,WHSC1,KLK5,NLRP3,IL5
GO:0006658	phosphatidylserine metabolic process	GO_PHOSPHATIDYLSERINE_METABOLIC_PROCESS	-0.328997662978783	-1.12764567570125	0.277368409475838	0.71097849599978	26	PLA2G2A,LIPC,PLA2G16,PLA2G2D,PLA2G4F,SERINC2,LPCAT3
GO:0051923	sulfation	GO_SULFATION	0.400093579514262	1.14965588802514	0.277514451941486	0.71097849599978	15	SULT1A2,NDST1,SULT1C4
GO:0048332	mesoderm morphogenesis	GO_MESODERM_MORPHOGENESIS	-0.261239691233149	-1.10067698366148	0.277610152705162	0.71097849599978	64	TBX6,ITGA3,BMP4,WNT5A,T,FGFR2,FOXF1,CRB2,ACVR1,KLF4,NR4A3,SMAD2,ETV2,EPHA2,NODAL,INHBA,AXIN1,ITGB4,WNT3,NOG,TWSG1,TRIM15,FOXC1,EOMES,WNT3A,EXT2,BMP7
GO:0060251	regulation of glial cell proliferation	GO_REGULATION_OF_GLIAL_CELL_PROLIFERATION	-0.350721007927763	-1.13544700015391	0.277941465330976	0.71097849599978	21	UFL1,PRKCI,SOX11,TSPO,CERS2,ADCYAP1
GO:0003205	cardiac chamber development	GO_CARDIAC_CHAMBER_DEVELOPMENT	0.235233280985654	1.08693280233911	0.278099201515767	0.71097849599978	134	UBE4B,ANK2,TBX2,SCN5A,RYR2,HAND2,NDST1,MYBPC3,BMP10,NACA,XIRP2,SUFU,SMARCD3,CAV3,DCTN5,NPRL3,PKP2,TNNI3,MYH7,EGLN1,CRELD1,TMEM65,DLL4,DAND5,LTBP1,MYL2,GJA5,TBX5,TBX20,LUZP1,NKX2-5,TEK,NPY5R,FHL2,RXRA,TNNT2,WNT11,HEY2,SMAD7,FGF8,PLXND1,PROX1,TBX3,MED1,MEF2C,SRF,DSP,PTCD2,TGFBR3,SMO,FOXC2,RARB,MYOCD
GO:0046434	organophosphate catabolic process	GO_ORGANOPHOSPHATE_CATABOLIC_PROCESS	-0.233771784367758	-1.08407432019214	0.278181425796705	0.71097849599978	108	SMPDL3B,APOA2,SMPD3,MTMR7,LIPC,MPG,NUDT18,DUT,ENTPD2,GPD1,SMPDL3A,NUDT5,CAT,ANGPTL3,PDE11A,SMUG1,NEIL2,PLA2G4F,INPP5E,NT5M,INPP5K,GDA
GO:0016073	snrna metabolic process	GO_SNRNA_METABOLIC_PROCESS	0.263984445939579	1.10157973896512	0.278832271014544	0.71210123234822	73	ELL3,NCBP1,SNAPC3,ELL,INTS2,EXOSC4,ZC3H8,EXOSC7,TUT1,POLR2I,INTS3,RPRD1A,NCBP2,SRRT,EXOSC3,POU2F1,TAF6,GTF2F2,POLR2C,RPRD1B,SNAPC4,PHAX,TAF11,POLR2G,CCNT1,MEPCE,POLR2L,INTS5
GO:0007618	mating	GO_MATING	-0.302132509610553	-1.11555295703112	0.27978307254623	0.713987734791972	35	P2RX1,PI3,DRD5,UBE2Q1,TACR1
GO:0017038	protein import	GO_PROTEIN_IMPORT	0.232976342190716	1.08440804924371	0.280138314919457	0.71418184913686	141	OR1D2,AGT,ADAR,PIK3R1,PRICKLE1,RANBP6,TSC2,NUP85,RERE,RAE1,POLA2,PEX14,JAK2,LONP2,NUP188,TIMM17B,TNF,PEX7,IPO8,MAPK1,CBLB,KPNA4,KPNA3,PEX26,PEX12,TIMM22,TPR,CHCHD4,BCL6,KPNA6,NDUFA13,NFKBIA,EGF,TGFB3,TNPO3,TOMM40L,SPTBN1,MT3,JAK3,NUP214,TOMM40,SIX2,PEX3,RBM22,NCKIPSD,KPNB1,MCM3AP,NUP35,IPO7,PDIA3,PEX19,PEX13
GO:0044550	secondary metabolite biosynthetic process	GO_SECONDARY_METABOLITE_BIOSYNTHETIC_PROCESS	-0.360545280872927	-1.1355568452847	0.280420522177332	0.71418184913686	19	CYP11A1,PMEL,BDH2,CYP1A2,SLC45A2,ASIP
GO:0010460	positive regulation of heart rate	GO_POSITIVE_REGULATION_OF_HEART_RATE	0.356720978126706	1.13623635576651	0.280495663861833	0.71418184913686	22	TRPM4,ADRB1,RYR2,HRC,TACR3,ADA,HEY2,ATP2A2,ADM,UTS2
GO:0007620	copulation	GO_COPULATION	-0.371748443175379	-1.13691983530867	0.281113466280227	0.714818675863525	17	P2RX1,PI3,TACR1
GO:0009218	pyrimidine ribonucleotide metabolic process	GO_PYRIMIDINE_RIBONUCLEOTIDE_METABOLIC_PROCESS	0.378221182137966	1.14109014092776	0.281170507083573	0.714818675863525	18	UPP2,ENTPD4,UCKL1,NME6,NME5,CAD,DHODH,UMPS
GO:2000107	negative regulation of leukocyte apoptotic process	GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	-0.289932471712143	-1.11055802355465	0.281461404058958	0.714857874224514	41	NOC2L,CCL19,BMP4,CCL21,SLC39A10,HIF1A,IRF7,RAG1,AURKB,MIF,GPAM
GO:0006813	potassium ion transport	GO_POTASSIUM_ION_TRANSPORT	-0.221133302624223	-1.07518796735065	0.281740668845369	0.714857874224514	145	SCN4A,SLC24A3,KCNH5,KCNV2,SLC9A7,CNGB1,KCNT2,KCNS2,KCNMB2,AQP1,KCNA3,KCNH1,KCNG1,CNGA4,HTR3A,FXYD4,KCNK16,SLC12A8,KCNAB2,KCNN1,KCNK15,KCNK1,KCNG3,KCNB1,KCNIP1,KCNA1,KCNN4,KCNQ4,KCNJ16,ATP4B
GO:0048145	regulation of fibroblast proliferation	GO_REGULATION_OF_FIBROBLAST_PROLIFERATION	-0.249132586485964	-1.09101408267946	0.281823053801524	0.714857874224514	78	MORC3,AQP1,WNT5A,NUPR1,S100A6,ANXA2,CTNNB1,B4GALT7,CDKN1A,EGFR,CCNB1,PPARG,CCNA2,SIRT6,BAX,FOSL2,MIF,MYC,PDGFD
GO:0070302	regulation of stress activated protein kinase signaling cascade	GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE	-0.211148378509447	-1.06781479306699	0.282151267313195	0.715151480253173	190	EDA2R,EZR,MAPK8IP1,TNFSF11,CCL19,FOXM1,ARHGEF5,TRAF4,WNT5A,SFRP2,BMP2,CTGF,MAP2K2,MDFIC,TNXB,MEN1,EDAR,TP73,PYCARD,CCL21,RIPK2,RIPK1,HDAC3,LEP,STK3,RPS3,MAGI3,FKTN,SH3RF1,ARL6IP5,HGF,ZNF675,TLR9,MAP3K11,NOD1,GRIK2,MID1,PHLPP1,MYC,EDN1,CDC42,FCER1A,MAP3K2,RASSF2,DLG1,AXIN1,CARD9
GO:0001836	release of cytochrome c from mitochondria	GO_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA	-0.353793837938164	-1.13057035703903	0.282385448849049	0.715206486701204	20	BBC3,SFN,GGCT,BAX,MFF,IFI6,BCL2,JUN
GO:0001764	neuron migration	GO_NEURON_MIGRATION	0.245497690933662	1.08967437992021	0.283747932745314	0.717686612720651	104	NDE1,MARK2,CDKL5,NRP1,DNER,TUBB2B,BARHL2,PAFAH1B1,KIAA0319,MARK1,DRD2,GJA1,RAPGEF2,DCLK1,UNK,FGFR1,TBX20,FBXO45,PEX7,PAX6,LHX1,PRKG1,NDNF,NTRK3,AXL,DDIT4,GATA2,NR2F2,MEF2C,SRF,TWIST1,TOP2B,ASCL1
GO:0060627	regulation of vesicle mediated transport	GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT	-0.188342385948495	-1.04751426327551	0.283858256474687	0.717686612720651	433	VTN,RSPO1,ATP13A2,CFTR,C3,HAP1,C4A,C2,SMPD3,EZR,APOC1,SYT4,CCL19,NLGN1,PRKD1,WNT5A,SYN1,C4BPA,RUFY1,RIMS4,RAB27B,SYTL1,GAS1,SNAP91,ANO6,ANGPT1,ALOX15,SYT17,MAP2K2,SDC1,SCFD1,FOXF1,TRIM9,LMAN2,IQCF1,PROM2,SNCA,CALR,ANXA1,ANXA2,PRTN3,RAB3B,RPH3A,RAB3C,C4BPB,TOR1A,CALY,C2CD4D,PYCARD,CCL21,TBC1D2B,STXBP3,TBC1D2,SNF8,PCLO,TULP1,ADIPOQ,TBC1D12,DAB2,ANXA13,ABCA7,SYT6,STX18,CDK5,VAMP8,CACNA1I,SORL1,PPARG,UNC13B,MAGI2,NR1H3,TBC1D9B,PROS1,MBL2,KCNB1,PICK1,SLC30A8,SYT5,STXBP1,STXBP5L
GO:0090303	positive regulation of wound healing	GO_POSITIVE_REGULATION_OF_WOUND_HEALING	-0.281443564452662	-1.10671171529592	0.284004328028493	0.717686612720651	46	VTN,ANO6,ANXA1,INSL3,F7,HPSE,F2,HOPX,S100A9,MYOD1,SOX15,THBS1,F2R,NFE2L2,PTGER4,F3,THBD,HRAS
GO:0051494	negative regulation of cytoskeleton organization	GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION	0.219637169140016	1.07281195096186	0.284288988934514	0.717867019320011	201	SHANK3,CEP192,SPTB,SPAG5,TUBGCP5,WDR62,BIRC8,NPM1,MAP1A,CLASP1,TBCD,DLC1,SBDS,SHANK1,TUBGCP2,ARHGEF2,ARAP1,GOLGA2,LMOD1,LMOD3,INPP5J,DYNC1H1,ADD1,CAV3,PPP1R9A,GPSM2,SMC1A,MAP4,CAPZB,TMOD1,KIFC1,S1PR1,TUBG1,RGS14,NCOR1,HDAC6,PPFIA1,ARFGEF1,APC,FHOD3,TUBGCP6,RDX,MKKS,KANK1,GAS2L2,HAUS8,TUBGCP3,CKAP5,PFN2,UVRAG,TMEFF2,ESPL1,CAPG,EML1
GO:0043392	negative regulation of dna binding	GO_NEGATIVE_REGULATION_OF_DNA_BINDING	0.296971823707573	1.11246847618395	0.285673120216119	0.719425367974882	43	HABP4,HDAC2,PPARA,HAND2,NFIB,SP100,JAK2,LHX2,CTNNBIP1,HEY2,MDFI,SUMO1,NFKBIA,MSX1,SMO,ANKRD33,SIN3A
GO:0061217	regulation of mesonephros development	GO_REGULATION_OF_MESONEPHROS_DEVELOPMENT	-0.330337884954336	-1.12054732722219	0.285733119465624	0.719425367974882	25	PAX8,WT1,BMP4,WNT2B,GATA3
GO:0098586	cellular response to virus	GO_CELLULAR_RESPONSE_TO_VIRUS	0.376775125058175	1.13672739882104	0.285756726145162	0.719425367974882	18	ADAR,BAD,GLI2,DDX58
GO:0045624	positive regulation of t helper cell differentiation	GO_POSITIVE_REGULATION_OF_T_HELPER_CELL_DIFFERENTIATION	-0.364531862272434	-1.13203688098515	0.286184852096652	0.719425367974882	18	CCL19,RARA,ANXA1,RIPK2,NLRP3
GO:0002710	negative regulation of t cell mediated immunity	GO_NEGATIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY	0.390098489964923	1.13984244076702	0.286218752904005	0.719425367974882	16	XCL1,SPN,CEACAM1,LILRB1,FOXP3,PPP3CB
GO:0032465	regulation of cytokinesis	GO_REGULATION_OF_CYTOKINESIS	0.275811018540679	1.10378228214668	0.28673854255622	0.719425367974882	59	TAS2R13,FLCN,BIRC6,KLHL21,VPS4A,CALM3,PIN1,SVIL,DRD2,PIK3C3,E2F8,CALM1,TAS1R2
GO:0009914	hormone transport	GO_HORMONE_TRANSPORT	-0.252098691071711	-1.09078287830757	0.28693760414738	0.719425367974882	73	SMPD3,UBE2Q1,ILDR2,GATA3,ANXA1,STXBP3,SNAP23,PCLO,EIF2AK3,LEP,SLC18A2,SMAD2,GPR119,SLC30A8,GAL,ACVR2B,CARTPT,CYB5R4,TMF1,EDN1,INHBA,SLC16A2
GO:0060292	long term synaptic depression	GO_LONG_TERM_SYNAPTIC_DEPRESSION	0.396888605687638	1.14044649997343	0.286957006635811	0.719425367974882	15	SLC24A2,ARF1,PTEN,ABHD6,GRIA1,GRID2IP,CD38,SRF
NA	regulation of tyrosine phosphorylation of stat5 protein	GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT5_PROTEIN	0.364832949089414	1.13247978783717	0.287028127313101	0.719425367974882	20	JAK2,GH1,ERBB4,IL4,CSF2,IL2
GO:0043270	positive regulation of ion transport	GO_POSITIVE_REGULATION_OF_ION_TRANSPORT	0.216209100273016	1.06980996638003	0.287457383814821	0.719425367974882	222	P2RY1,SHANK3,NLGN3,PDGFB,ANK2,LPAR3,DRD4,ADRB2,TRPV2,SCN5A,P2RY2,CALM3,CAMK2A,CACNA2D1,RYR2,S100A1,KIF5B,WNK1,CAPN3,XCL1,LGALS3,DRD2,OPRK1,RNF207,KCNJ2,SLC6A1,WNK2,ADCYAP1R1,CXCL11,PINK1,ARF1,AKAP6,DMD,RAB3GAP1,CXCR3,UCN,PKP2,FXYD1,KCNH2,CALM1,MYLK,GLRX,GABBR1,NKX2-5,PARK7,CNTN1,HOMER1,P2RX7,ANK3,CXCL9,SLC38A3,PLCG1,ABCB4,PTAFR,ZP3,HTT,FGF12,TRDN,SUMO1,JPH2,CNKSR3
GO:0001556	oocyte maturation	GO_OOCYTE_MATURATION	-0.369823916891421	-1.13103404843862	0.287515681100489	0.719425367974882	17	INSL3,REC8,CCNB1,KIAA0196,FBXO5,FOXO3,PABPC1L,RPS6KA2,PTK2B
GO:0097006	regulation of plasma lipoprotein particle levels	GO_REGULATION_OF_PLASMA_LIPOPROTEIN_PARTICLE_LEVELS	-0.285449591613692	-1.1050615407231	0.287744227353464	0.719425367974882	43	PLA2G2A,APOA2,APOC1,LIPC,AGTR1,DGAT2,LPL,ADIPOQ,ABCA7,ABCA1,PLTP,LPCAT3,APOM,ABCG1
GO:0043631	rna polyadenylation	GO_RNA_POLYADENYLATION	0.328474727158422	1.12264049511233	0.287842006315367	0.719425367974882	29	PAF1,APP,WDR33,TUT1,CLP1,CPSF1,SYMPK,PAPOLG,CPSF6,MTPAP,CSTF3,PCF11,GRSF1,PNPT1,PAPD4,CPSF3,ZC3H3
NA	positive regulation of mrna 3 end processing	GO_POSITIVE_REGULATION_OF_MRNA_3_END_PROCESSING	0.389343241269206	1.13763565315093	0.288356100734133	0.719425367974882	16	CPEB3,PAF1,NCBP1,TNRC6C,TNRC6B,NCBP2
GO:0033209	tumor necrosis factor mediated signaling pathway	GO_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY	-0.232119809162199	-1.07780712407881	0.288405170342607	0.719425367974882	109	TNFRSF8,KRT8,EDA2R,TNFSF11,TNFRSF21,TNFSF14,TNFRSF11B,KRT18,TXNDC17,CARD14,EDAR,TJP2,PYCARD,RIPK1,TRADD,UBA52,TNFRSF1A,PSMB11,TNFRSF25,FAS,PSMD10,CLDN18,PSMD5,PSMD13,PSMB5,FOXO3,UBB,EDARADD,PSMA6,PSMA4
GO:0007052	mitotic spindle organization	GO_MITOTIC_SPINDLE_ORGANIZATION	0.272211317030343	1.10058538063449	0.288877071700789	0.719425367974882	62	TUBGCP5,WDR62,BIRC8,CLASP1,SBDS,TUBGCP2,GOLGA2,DYNC1H1,GPSM2,SMC1A,MAP4,KIFC1
GO:0048514	blood vessel morphogenesis	GO_BLOOD_VESSEL_MORPHOGENESIS	0.204600917785677	1.06081210355908	0.288950276243094	0.719425367974882	336	ROBO4,AMOT,LRP5,NRP1,EPAS1,PTPRB,TBX2,NRXN1,NOTCH3,SERPINF2,ZNF304,TIE1,ATPIF1,RNF213,FLT1,AAMP,ITGB3,BMPER,HAND2,EPHA1,YAP1,CEACAM1,CDH2,QKI,EYA1,PRKX,COL15A1,VEGFB,GJA1,CHD7,FGF1,PTEN,NPRL3,CXCR3,ADIPOR2,SLC12A6,TGFBR2,HSPG2,NFATC4,ATP5B,TNNI3,E2F8,SIX1,HS6ST1,SHH,CX3CL1,DLL4,RASIP1,FGFR1,MYLK,ARHGAP22,TCF21,CDH13,GJA5,COL18A1,ZMIZ1,TBX5,TBX20,WARS,TSPAN12,S100A7,S1PR1,PDCD6,SEMA5A,NKX2-5,TEK,MCAM,SOX17,VEGFA,HOXB3,ETS1,ENG,PLCD3,PLAU,SH2D2A,WNT11,SPI1,HEY2,GJC1,SMAD7,FGF6,LAMA5,JMJD6,FGF8,BCAS3,PNPLA6,FOXN1,PLXND1,NDNF,EGF,PROX1,COL4A1,MED1,BAK1,CSPG4,ADM,NR2F2,SRF,GPI,PAXIP1,PIK3R6,PGF,PIK3CB,COL8A2,EREG,SEC24B,STK4,SMO,FOXC2,MYOCD,TMPRSS6
GO:0060191	regulation of lipase activity	GO_REGULATION_OF_LIPASE_ACTIVITY	-0.24742933917269	-1.08627349770561	0.289131092945807	0.719425367974882	79	APOA2,APOC1,AVPR1B,FGFR2,LPAR1,CYR61,SNCA,ANXA1,AGTR1,ANGPTL3,EGFR,ANGPTL4,C5AR1,NR1H3,PDPK1,TXK,LRP1,RHOA,GNA13,ABL1,RGS2,HPCA,FGF2,HTR2A,RHOC,ARF4,GPR55,ABHD5
GO:0015721	bile acid and bile salt transport	GO_BILE_ACID_AND_BILE_SALT_TRANSPORT	0.331141262613626	1.12204918097687	0.289146932431197	0.719425367974882	28	SLC10A5,SLC27A5,CEACAM1,SLC10A4,RXRA,SLC10A6,SLCO1B1,ABCB4,NCOA1,ATP8B1
GO:0030540	female genitalia development	GO_FEMALE_GENITALIA_DEVELOPMENT	-0.376942950805841	-1.13261871397572	0.289239561010455	0.719425367974882	16	RBP4,TYRO3,WNT5A
GO:0043200	response to amino acid	GO_RESPONSE_TO_AMINO_ACID	-0.233697101570731	-1.07898478454958	0.289394518193105	0.719425367974882	105	ASS1,UFL1,LIPC,ALDOB,BCHE,CTGF,CEBPB,PEMT,SOCS1,IPO5,ZNF354A,XBP1,EGFR,CHUK,CPS1,TYMS,CASP3,GLRA4,RAPGEF3,SST,FAS,HMBS,CAPN2,RRAGC,CPEB4,EDN1,PDGFD,PTGER4,EEF2,HPCA,LAMTOR1
GO:0021799	cerebral cortex radially oriented cell migration	GO_CEREBRAL_CORTEX_RADIALLY_ORIENTED_CELL_MIGRATION	-0.325729321160673	-1.11644337266804	0.290499967006137	0.719927066118524	26	RTN4,FUT10,POU3F2,POU3F3,CTNNB1,CDK5
GO:0050951	sensory perception of temperature stimulus	GO_SENSORY_PERCEPTION_OF_TEMPERATURE_STIMULUS	-0.351411856368051	-1.12295858581691	0.290674905356599	0.719927066118524	20	TRPM3,LXN,MMP24
GO:0001938	positive regulation of endothelial cell proliferation	GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	-0.26079164134415	-1.09261275668975	0.291095968981577	0.719927066118524	62	PRKCA,SCG2,KDR,TGFBR1,PRKD1,BMP4,WNT5A,BMP2
GO:0048532	anatomical structure arrangement	GO_ANATOMICAL_STRUCTURE_ARRANGEMENT	-0.368468103362662	-1.12688755819199	0.291646839987888	0.719927066118524	17	SEMA3F,SEMA3A,PLXNA4,RAC1,KCNA2,TFAP2A,HOXB2
GO:0010830	regulation of myotube differentiation	GO_REGULATION_OF_MYOTUBE_DIFFERENTIATION	0.281705103864794	1.10341536906881	0.291733676423287	0.719927066118524	53	EHD1,HDAC9,CFLAR,ANKRD2,DMPK,NACA,HDAC4,CAV3,SMYD1,MTOR,IL4,NKX2-5,SCGB3A1
GO:0060711	labyrinthine layer development	GO_LABYRINTHINE_LAYER_DEVELOPMENT	-0.284687191925082	-1.1021100613751	0.291926164084808	0.719927066118524	43	PLCD1,SPINT1,GRHL2,FGFR2,TMED2,CYR61,WNT7B,ST14
GO:0050679	positive regulation of epithelial cell proliferation	GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION	-0.220555445017132	-1.07006542645808	0.29200560320464	0.719927066118524	143	TGM1,PRKCA,SCG2,EPGN,OSR1,KDR,TGFBR1,PRKD1,BMP4,WNT5A,BMP2,FGF7,HTRA1,FGFR2,SOX11,TACR1,XBP1,CTNNB1,MMP12,NR4A3,EGFR,HIF1A,BMP5,CDH3,C5AR1,FGF9,DLX6,HMGB2,ZNF703,VASH2,NODAL,MYC,CDC42,THBS4,F3,SIRT1,RICTOR,FGF2,WNT7A,HRAS,NOG,MAP2K5,JUN
NA	positive regulation of interleukin 6 secretion	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_SECRETION	-0.375941001600166	-1.12960810874122	0.292205121544689	0.719927066118524	16	XBP1,PYCARD,IL17RC,IL17F,F2R
GO:0007264	small gtpase mediated signal transduction	GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	0.205072527673204	1.05958942498901	0.292344967378223	0.719927066118524	325	RHOT2,RASGRP2,GNA12,RAPGEF1,RAB30,MAPKAPK2,ZNF304,RAPGEF4,TIAM1,RAB6A,RAB21,ALS2,DIRAS2,RAPGEF6,ROCK2,LRRK2,RASGRP3,PLD1,RALGPS1,RAB2B,CRKL,RABL2A,RAB12,ABR,MAPKAPK3,MFHAS1,RHOV,ARF1,MYO9B,PLCE1,RASL12,RASGRF1,RAPGEF2,RAB1B,RASGEF1A,NKIRAS2,CFL1,ARHGAP35,RAPGEF5,DOCK4,DIRAS1,SETDB1,RABL2B,IFT27,LIMK1,RAB6B,DNAJA3,MAPKAPK5,ARL1,RHOF,RAP2C,RAB41,CDH13,DBNL,RAB40AL,FARP2,BRAP,RALGDS,RERGL,PARK7,RAB9B,RAB28,USP28,RHOBTB2,RHOH,C15orf62,ARL15,ELMO1,RRAD,PTH,LRRK1,G3BP1,BCL6,RALGPS2,RAPGEFL1,ARF6,DIRAS3,RAB3A,RASSF1,RAB44,AGAP1,NKIRAS1,NISCH,DOCK3,ARL13A,ARL9,RASEF,SIAH2,GRB2,KPNB1,ARL5B,RAB26,RND1,RASL10B,RGL3,ARL8B,EPS8L2,GDI1,RASGEF1C,RGL4,CDC42EP5,DNAJC27,NF1,CDKN2A,RGS19,RGL2,RAB14,SHC1,DOCK6,RAB24,TRIM28,RASGRP1,RAP2A,AGAP2,DOCK10,REM2,RASGRF2,RIT1,RAB32,ARFRP1,VAV3,ARHGAP31,RAB8A
GO:0051926	negative regulation of calcium ion transport	GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT	0.293076018724232	1.10852415969509	0.29258333183429	0.719927066118524	45	OPRL1,DRD4,CALM3,ATP1A2,DRD2,CAV3,PLN,CALM1,SEMG1,SLC30A1,GNAO1,TRDN,LILRB1
GO:0009952	anterior posterior pattern specification	GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION	-0.211792485911581	-1.06339581972468	0.29276290896249	0.719927066118524	181	SEMA3C,HOXA6,TBX6,OSR1,WT1,CDON,TGFBR1,BMP4,WNT5A,SFRP2,HOXA3,BMP2,T,HOXA7,TMED2,FOXF1,CRB2,HOXC10,GBX2,OTX2,OTX1,COBL,CTNNB1,PLXNA2,FEZF1,NLE1,MSX2
GO:0008299	isoprenoid biosynthetic process	GO_ISOPRENOID_BIOSYNTHETIC_PROCESS	0.353161975923794	1.12490013518751	0.292868847931358	0.719927066118524	22	IDI2,HMGCR,MVD,GGPS1,HMGCS2,HMGCS1,IDI1,FDFT1,CYP1A1,COQ2
GO:0008643	carbohydrate transport	GO_CARBOHYDRATE_TRANSPORT	-0.241200549273902	-1.0821159215483	0.29326278659612	0.719927066118524	89	SLC5A9,EZR,SLC35D3,SLC45A3,AQP1,SLC35E1,AQP3,AQP8,SLC2A5,SESN2,STXBP3,SLC35A3,HK2,SLC2A10,SLC5A2,AQP11,SLC2A2,SLC37A1,SLC2A1,EDN1,SLC23A2,AQP9,SLC5A11,G6PC
GO:0032757	positive regulation of interleukin 8 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION	-0.285708147356397	-1.10086020527282	0.293417335545491	0.719927066118524	42	APOA2,WNT5A,PYCARD,RIPK1,ADIPOQ,TLR9,F2R,TLR2,ELANE,PTGER4,AFAP1L2,CAMP,TLR3,CD58,CALCA
GO:0072091	regulation of stem cell proliferation	GO_REGULATION_OF_STEM_CELL_PROLIFERATION	0.254842517455142	1.08963244184052	0.293482823759882	0.719927066118524	84	LRP5,ZEB1,LRRK2,FBXW4,YAP1,DRD2,NFIB,PDCD2,CTNNA1,SMARCD3,TGFBR2,SIX1,SHH,CX3CL1,FGFR1,CTNNBIP1,SOX17,VEGFA,ATXN1L,PAX6,SOX9,WNT11
GO:0042537	benzene containing compound metabolic process	GO_BENZENE_CONTAINING_COMPOUND_METABOLIC_PROCESS	0.374268627606784	1.12916531698873	0.293889373711867	0.719927066118524	18	CYP2E1,CYP17A1,HAAO,IDO1,GOT2
GO:0006109	regulation of carbohydrate metabolic process	GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS	0.229806580358036	1.07582837945192	0.294156281576288	0.719927066118524	147	P2RY1,BAD,AKT2,PDGFB,PPARA,IGFBP3,GRB10,PGAM2,PGAM1,GOLGA2,ADCYAP1R1,HDAC4,GSK3B,PRKAA2,ACER2,IRS1,GCK,KAT2A,PPP1R3B,PPP1R3F,COX11,MTOR,FOXO1,NCOR1,ARFGEF1,P2RX7,PPP1CB,SERPINA12,PTAFR,NFKB1,HMGB1,ACACB,PPP1R3E,PASK,PTH,PRKCE,EGF,PHKG2,DDIT4,PTH1R,CBFA2T3,PRKAG1,GCG,EPM2AIP1,MT3,SORBS1,PDK3,IGFBP5
GO:0050663	cytokine secretion	GO_CYTOKINE_SECRETION	-0.296941404427435	-1.10372122493485	0.294159591773069	0.719927066118524	36	CHI3L1,CCL19,GATA3,S100A12,LEP,ABCA1,NLRP3,TLR2,VTCN1,GPAM
GO:0097479	synaptic vesicle localization	GO_SYNAPTIC_VESICLE_LOCALIZATION	-0.237822552849677	-1.0787318715893	0.294295857988166	0.719927066118524	95	STX19,SYT4,SNAP25,NLGN1,SYTL1,AP3M1,SYT17,TRIM9,SNCA,CANX,RPH3A,CTNNB1,TOR1A,C2CD4D,SNAP23,PCLO,STX11,SYT6,CDK5,UNC13B,AP3S1,SYT5,STX2
GO:0006505	gpi anchor metabolic process	GO_GPI_ANCHOR_METABOLIC_PROCESS	-0.309589035697138	-1.10892669945727	0.294568491936913	0.719927066118524	31	PIGV,PIGW,PIGX,PLAUR,PIGU,PIGZ,PIGF,PIGQ,PIGK
GO:2000378	negative regulation of reactive oxygen species metabolic process	GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS	-0.29061667821683	-1.10042194497728	0.294757577114205	0.719927066118524	39	PTGIS,HP,TSPO,OPRM1,STAT3,HIF1A,SLC18A2,HK2,CD34,MYCN,PTGER4,IL10,BCL2
GO:0050921	positive regulation of chemotaxis	GO_POSITIVE_REGULATION_OF_CHEMOTAXIS	-0.228316268792576	-1.07334604026293	0.294868077703682	0.719927066118524	117	IL16,SCG2,CCL3,CCL19,KDR,PRKD1,WNT5A,MET,CCR6,TNFSF14,ANO6,LPAR1,CALR,CXCL1,FGF18,F7,CCL21,CSF1,ARTN
GO:0051580	regulation of neurotransmitter uptake	GO_REGULATION_OF_NEUROTRANSMITTER_UPTAKE	0.394290636439958	1.132981319837	0.294875369430659	0.719927066118524	15	GPM6B,DRD4,ATP1A2,DRD2
GO:0032373	positive regulation of sterol transport	GO_POSITIVE_REGULATION_OF_STEROL_TRANSPORT	-0.375152267208967	-1.12723816037127	0.29488927852458	0.719927066118524	16	ADIPOQ,ABCA7,ABCA1,PLTP,NR1H3,ABCG1,LRP1,SIRT1
GO:0036503	erad pathway	GO_ERAD_PATHWAY	0.26538587447478	1.09319300462593	0.295011533517635	0.719927066118524	68	FBXO6,ANKZF1,RNF121,EDEM2,PSMC6,USP13,SEL1L,MARCH6,PSMC5,KIAA0368,DERL3,TRIM13,DNAJB2,TMUB1,YOD1,VCP,NPLOC4,BAG6,RHBDD1
GO:0001964	startle response	GO_STARTLE_RESPONSE	0.343626659434629	1.11971708124894	0.295371833988898	0.719927066118524	24	GRIN3A,NRXN1,DRD2,FABP7,PTEN,UCN
GO:0009583	detection of light stimulus	GO_DETECTION_OF_LIGHT_STIMULUS	-0.266109220768867	-1.09102361860407	0.295386226999453	0.719927066118524	56	CNGB1,BEST1,GUCY2F,PDE6C,GNAT1,CACNA1F,OPN1LW,TULP1,AIPL1,OPN3,CACNB4,RS1,PITPNM1,GUCA1A,GNGT1,EYS,GRM6,CDS1,ATP8A2,PDE6G,PDE6A,RCVRN,OPN1SW
GO:0010939	regulation of necrotic cell death	GO_REGULATION_OF_NECROTIC_CELL_DEATH	0.343519750661552	1.11936871602155	0.295702679851487	0.719927066118524	24	RBCK1,CFLAR,ARHGEF2,PPIF,SLC25A4,UCN
GO:0032649	regulation of interferon gamma production	GO_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION	-0.240812816879036	-1.08037640893505	0.2959670781893	0.719927066118524	89	RARA,IL18,WNT5A,GATA3,HLA-DRB5,IL27,PYCARD,RIPK2,RIPK3,TNFSF9,CEBPG,PGLYRP1,TLR9,IFNAR1,TXK,HLA-DRB1,INHBA,ABL1,IL20RB,CD276,IL10,ISL1,HRAS,PDE4B,PGLYRP2,TLR3,TNFRSF13C
GO:0010226	response to lithium ion	GO_RESPONSE_TO_LITHIUM_ION	-0.324238648831403	-1.11133406523173	0.296262895101511	0.719927066118524	26	PKLR,CALR,SLC18A1,CTNNB1,CEBPA,FABP4,FAS,CDH1,PLA2G4A,NTS,XRCC4,PTK2B
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	-0.24703192366818	-1.08181475332038	0.296479250646597	0.719927066118524	78	NOC2L,MAPK8IP1,TAF9B,KDM1A,SFRP2,MUC1,CREB3L1,TXNDC12,XBP1,FIGNL1,NONO,HIF1A,RRM2B,PLAUR,TPT1,MAGEA3,BDKRB2
GO:0046639	negative regulation of alpha beta t cell differentiation	GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.393631963479462	1.1310886445078	0.296808490864142	0.719927066118524	15	HLX,SHH,IL4,HMGB1,BCL6,TNFSF4,JAK3,FOXP3,RC3H1
GO:0043266	regulation of potassium ion transport	GO_REGULATION_OF_POTASSIUM_ION_TRANSPORT	0.256329341885383	1.08738443677682	0.296865967100538	0.719927066118524	80	ANK2,VIP,ADRB2,KIF5B,NEDD4L,DRD2,OPRK1,RNF207,KCNJ2,VAMP2,AKAP6,CAV3,GCK,PLCB4,KCNH2,KCNA5,KCNRG,ANK3,KCNIP2
GO:0048261	negative regulation of receptor mediated endocytosis	GO_NEGATIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS	0.386690888017977	1.12988564928926	0.296868320788031	0.719927066118524	16	LRRTM2,DLG4,UNC119,APOC3
GO:0045648	positive regulation of erythrocyte differentiation	GO_POSITIVE_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION	-0.344998567506321	-1.11692079937548	0.297911346821188	0.721771625353746	21	KDM1A,HIF1A,HMGB2,ACVR1B,FOXO3,MAPK11,INHBA
GO:0016601	rac protein signal transduction	GO_RAC_PROTEIN_SIGNAL_TRANSDUCTION	0.3862679772561	1.12864993152197	0.29805780131958	0.721771625353746	16	TIAM1,ALS2,CDH13,DBNL,FARP2,ELMO1,NISCH
NA	cofactor metabolic process	GO_COFACTOR_METABOLIC_PROCESS	0.206282192839278	1.05853528690242	0.298310428842142	0.721864057140654	304	COX15,IDH3B,ME1,PANK3,DLAT,CIAO1,AGK,OGDHL,ATPIF1,MCCC2,ACOT6,ACSM2A,ACOT2,NNT,DLD,PGAM2,PGAM1,LIPT2,RPIA,MTHFR,OGDH,HAAO,DHTKD1,HMGCR,FPGS,COASY,PDHA1,MVD,LIAS,ACOT11,NMNAT3,COX10,PFKM,SARDH,ACSF2,GCK,SLC5A6,COQ9,SUCLG2,MDH2,MDH1,NFS1,ELOVL6,ALAD,PFKFB4,PDHX,PFKP,ALDOC,PANK4,SLC25A32,ACOT8,MOCS2,VCP,PDHB,ALDOA,HK3,PCCB,ENO2,GALK1,IDH1,GPHN,RFK,THTPA,ACACB,GCDH,FXN,TPK1,PCCA,NDUFA9,DLST,HMOX2,MMS19,SHMT2,EIF2AK1,CYP1A1,VNN1,AKR7A2,NMNAT2,CIAPIN1,COQ2,SPR,PIPOX,GPI,PRDX5,MCEE,NFE2L1,TKT,NARFL,ADH4,QDPR,COQ5,ACSS1,SLC25A38,ADPGK,RSAD1,OXSM,PGK1,ELOVL7,FECH
GO:0048638	regulation of developmental growth	GO_REGULATION_OF_DEVELOPMENTAL_GROWTH	0.208659406866644	1.05997597536836	0.298986757302722	0.722980908822531	278	SEMA6A,GNAS,PPARD,CDKL5,NRP1,ADRB1,TBX2,STAT5B,LPAR3,SEMA6C,BARHL2,NPY1R,PAFAH1B1,APP,RAB21,ADRB2,TRPV2,PPP2R3A,HLX,PIN1,MEGF8,CACNA2D2,NEDD4L,CAPN3,MUSK,YAP1,DRD2,BMP10,GHSR,NACA,MACF1,GJA1,CHD7,GSK3B,AKAP6,CAV3,PTEN,CELF1,GH1,RASAL1,STC2,DDX39B,TGFBR2,GOLGA4,LIMK1,ITSN2,LATS1,SIX1,FGFR1,EP300,ERBB4,EPHA7,MTOR,TBX5,CCR2,TBX20,CREB1,FLVCR1,SEMA5A,NKX2-5,CDK1,VEGFA,PTCH1,SOD1,HEY2,MKKS,ZP3,AGR2,ACACB,FXN,FTO,L1CAM,RAI1,BCL11A,PRKDC,FOXS1,FGF8,PLXNA3,CPNE9,PLXND1,PROX1,NTRK3
GO:0060996	dendritic spine development	GO_DENDRITIC_SPINE_DEVELOPMENT	0.372591901412547	1.12410664809434	0.299571086395455	0.723873852697129	18	SHANK3,DLG4,SHANK1,PTEN
GO:0001701	in utero embryonic development	GO_IN_UTERO_EMBRYONIC_DEVELOPMENT	0.206476326323912	1.05787279874415	0.299813423910443	0.723939730905705	300	TET1,SMARCB1,CUL4A,AMOT,NASP,ADAR,GNA12,FLCN,ATP7A,PDGFB,EPAS1,TIE1,SLC39A3,BIRC6,MFN2,ALS2,P2RY2,SBDS,ELL,C2CD3,GLI2,IFITM5,HAND2,CDX4,GJA1,CHD7,ADD1,CHD8,TGFBR2,KAT2A,E2F8,EGLN1,NMT1,WDTC1,LATS1,HS6ST1,FGFR1,ADA,FOXD3,EIF4E2,ZMIZ1,FLVCR1,XAB2,CSF2,PLK4,RXRA,MAPK1,SOX17,VEGFA,PTCH1,SRSF1,PRPF19,PLCD3,TFEB,CDX2,HEY2,MAPK8IP3,PLCG1,BPTF,ZP3,NCOA1,SLC30A1,MDFI,ADAM10,GAB1,SMAD3,ENDOG,UBR3,GINS1,PCGF2,UBE2B,RRP7A,TGFB3,TBX3,MSX1,MED1,GDF3,GATA2,FOSL1,NSDHL,ADM,NR2F2,PLAC1,SRF,TWIST1,GPI,TJP1,HES3,RRN3,MAFF,BRCA2,APBA2
GO:0090502	rna phosphodiester bond hydrolysis endonucleolytic	GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_ENDONUCLEOLYTIC	0.283786989663433	1.09773456890425	0.300509856019533	0.724624905561878	50	NOL9,ELAC2,KIAA0391,SMG6,ABT1,RCL1,RNASEH2C,EDC3,DICER1,PLD6
GO:0090311	regulation of protein deacetylation	GO_REGULATION_OF_PROTEIN_DEACETYLATION	0.316587526822792	1.10835731055578	0.300613720383894	0.724624905561878	32	FRY,AKAP8,KDM5A,UCN,EP300,BRMS1,VEGFA,BCL6,MAPK8,AKAP8L,DYRK1A,FOXP3,C6orf89,TGFB1,CAMK2D,SREBF1,PRKD2,NIPBL,SPRED1,CTBP1
GO:0015908	fatty acid transport	GO_FATTY_ACID_TRANSPORT	0.278936081436503	1.09649183346796	0.300743016360649	0.724624905561878	54	SLC25A17,PPARD,SLC27A5,SLCO3A1,DRD4,PPARA,DRD2,PRKAB2,PLA2G5,ABCC2,PRKAA2,GOT2,SLC27A6,FABP3,NMUR2,ACACB,CD36
GO:0046037	gmp metabolic process	GO_GMP_METABOLIC_PROCESS	-0.348271050974453	-1.11292194556358	0.301466428789	0.725456250451767	20	GUK1,IMPDH2,TJP2,MAGI3,CASK,MPP3,DLG1,GMPS,PDE6A
GO:0051966	regulation of synaptic transmission glutamatergic	GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GLUTAMATERGIC	0.284959784973187	1.09754066733444	0.301519101123595	0.725456250451767	49	SHANK3,NLGN3,PRKACA,NRXN1,LRRK2,ATP1A2,DRD2,RAB3GAP1,UCN,NPS
GO:0022411	cellular component disassembly	GO_CELLULAR_COMPONENT_DISASSEMBLY	0.195580552658939	1.04929128011027	0.301898309222975	0.725790123095272	480	TFIP11,KLKB1,DPF3,SMARCB1,LRP5,PTCD3,MARK2,AURKAIP1,LPIN1,POM121,OBSCN,MYOM1,LAMC1,MAP1A,MRPL4,ATG14,MRPL16,ATPIF1,USP30,LRP6,DVL2,ACIN1,PAFAH1B1,MRPL41,VPS4A,MRPL14,ELN,KIF5B,MICAL3,MRPL19,MRPS15,APEH,NUP85,SLC6A1,MRPL53,NDUFB9,GOLGA2,PINK1,HMGA1,RAE1,ACAN,PEX14,CAPNS1,GSK3B,SMARCD3,CDK5RAP3,CHMP7,MTIF3,CFL1,WIPI2,MMP10,HSPG2,MRPL15,MRPL27,MRPS28,MDH1,DZANK1,HIST1H2BA,PI4K2A,MRPL24,MRPL35,WNT8B,MYLK,MRPL20,MRPL17,MMP7,NUP188,PFKP,MRPL12,LSM4,HBS1L,NEK9,EMD,ADAMTS7,ATG9A,MRPL37,MRPL51,HDAC6,CDK1,BANF1,APC,ENG,CD93,MMP11,DICER1,DNASE2B,REP15,MRPS22,MAP1LC3A,ZNF189,CLSPN,ADAMTS5,CECR2,ITPKC,CSNK1A1,MRPS18B,HMGB1,ADAM10,GBF1,MRPL39,CA7,ENDOG,WDR45,CFL2,TPR,AAAS,MRPS25,PRKG1,FAM13B,HPN,SATB1,H1F0,MRPL46,GSPT1,CAPS,POM121C,KLC1,MRPL18,DDIT4,FLOT1,FCGR3B,CAPG,MBD5,AKAP8L,CALCB,EIF2S1,RIMS3,PRKCQ,AMBRA1
GO:0007018	microtubule based movement	GO_MICROTUBULE_BASED_MOVEMENT	-0.210345324530552	-1.05879754201193	0.302089115405965	0.725790123095272	184	KIF2C,KIF18A,HAP1,KIF5A,TRAF3IP1,IFT57,DNAH3,KATNB1,DNAH2,DNAH6,AP3M1,WDR35,KIF20A,KLC3,SSX2IP,KIF3A,ACTR3,CCDC114,DNAL4,DNAH17,TTLL1,WDR19,HIF1A,DNAH1,TTC30B,KIF6,KIF7,WDR43,ADCY10,AP3S1,FMN2,PCM1,TTC26,KIF4A,DYNLL1,IFT20,KIF3C,KIF21A,CLN3,CDC42,DYNC1I1,ROPN1L,SNAPIN,UBB,DNAH5
GO:0002224	toll like receptor signaling pathway	GO_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	-0.24408791615241	-1.07702898505076	0.302367305093434	0.725940334482524	81	IRAK4,COLEC12,LY96,SCARA3,IRAK1,RIPK2,RIPK1,CHUK,UBA52,IRF7,IRAK3,TLR10,CNPY3,IKBKG,CTSK,TLR9,TLR2,UNC93B1,UBB,IKBKE
GO:0046039	gtp metabolic process	GO_GTP_METABOLIC_PROCESS	0.384540967985905	1.12360372264804	0.302982994145525	0.726136576849971	16	LRRK2,AK4,NFS1,NME6,MOCS2,GPHN,NME5
GO:0043524	negative regulation of neuron apoptotic process	GO_NEGATIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS	-0.223345141835981	-1.06569903527215	0.303017725474877	0.726136576849971	129	GDF5,TYRO3,DLX1,TOX3,MAP2K4,ANGPT1,KRAS,CEBPB,PRKCI,SNCA,CLCF1,NONO,TP73,NR4A3,STAR,HIF1A,C5AR1,GDNF,XRCC2,STXBP1,BAX,GRIK2,CPEB4,F2R,CLN3,ALKBH1,LRP1,BTG2,PSEN1,GABRB2,MAP3K12,BCL2,UBE2V2,ISL1,HRAS,ITSN1,JUN
GO:0001894	tissue homeostasis	GO_TISSUE_HOMEOSTASIS	-0.21675530433965	-1.06284822466646	0.303562580517293	0.726136576849971	154	SERPINA3,MUC2,RBP4,SLC28A3,AZGP1,TNFSF11,CNGB1,CD7,IQCB1,ILDR2,POTEE,CTGF,FGF7,KRAS,ACTG1,MUC6,CTNNB1,USH1G,CSF1,PRLH,TULP1,PRDM14,AIPL1,CDH3,PIGR,CTSK,ZNF675,TLR9,CD34,BAX,IGKC,BARD1,F2R,RP1L1,WDR36,BBS10,IL20RB,CST4,BCL2,POTEF,PLA2G4A,LYZ,CYTL1,ACACA,RAC1
GO:0098751	bone cell development	GO_BONE_CELL_DEVELOPMENT	0.350101784434903	1.11515273865495	0.303566496658136	0.726136576849971	22	PAFAH1B1,EP300,FLI1,C6orf25,LRRK1,MED1,SRF,ABI1,FOXP1,VPS33B,TAL1,MEIS1
GO:0071103	dna conformation change	GO_DNA_CONFORMATION_CHANGE	0.212887171408646	1.06131387253811	0.303848279000228	0.726136576849971	236	CUL4A,HILS1,NASP,TOP3B,DDX3X,CENPK,NPM1,PAF1,MCM4,HIST1H2BO,CENPA,ACIN1,AKAP8,NCAPH,HIST1H3G,MCM7,HIST1H3B,IGHMBP2,HMGA1,HELLS,PRM1,CHD8,HIST1H4F,HP1BP3,FBXO18,ZRANB3,HIST1H2BC,KAT6A,TTN,PSME4,GTF2H3,H3F3A,HIST1H2BA,SMC2,H2BFWT,SETX,RECQL5,CENPN,CDK1,NCAPD3,HIST1H3E,GTF2H5,ASF1B,SOX9,ATRX,HIST2H2BE,HMGB1,CENPI,UBN1,G3BP1,GINS1,MRE11A,TSPYL5,ASF1A,H1F0,HIST2H2BF,H1FX,KAT6B,AKAP8L,HIST1H4A,HIST1H1D,AIFM1,TOP2B,WRN,PAPD7,PHF13,SART3,CENPO,HIST1H1T,CENPV,CENPT,TSPYL6,HIST3H3
GO:1902808	positive regulation of cell cycle g1 s phase transition	GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION	0.327598656418394	1.11004530580737	0.303885891926488	0.726136576849971	28	CUL4A,DDX3X,CREBBP,FAM83D,KCNA5,ANKRD17,RDX,CYP1A1,PPP1R1C
GO:0032225	regulation of synaptic transmission dopaminergic	GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_DOPAMINERGIC	-0.372350748647327	-1.11882030206226	0.303959131545338	0.726136576849971	16	SNCA,RAB3B,TOR1A,CHRNB2,GDNF,KCNQ4
GO:0001892	embryonic placenta development	GO_EMBRYONIC_PLACENTA_DEVELOPMENT	-0.243386493561133	-1.07588256474992	0.304575285517435	0.727092490107578	82	KRT8,KRT19,PLCD1,SPINT1,CEBPB,GRHL2,FGFR2,TMED2,CYR61,CEBPA,EGFR,WNT7B,HIF1A,ST14
GO:0031063	regulation of histone deacetylation	GO_REGULATION_OF_HISTONE_DEACETYLATION	0.345219294618097	1.11307284902877	0.305499430586679	0.728781774170633	23	AKAP8,KDM5A,UCN,VEGFA,BCL6,MAPK8,AKAP8L,FOXP3,C6orf89,TGFB1,CAMK2D,SREBF1,PRKD2,NIPBL,CTBP1
GO:0061512	protein localization to cilium	GO_PROTEIN_LOCALIZATION_TO_CILIUM	-0.325211938305524	-1.10315947654438	0.305904067148601	0.729049151335248	25	C5orf42,WDR35,SNX10,TULP1,TULP2,IFT20,TULP3,ARF4,IFT140
GO:0002711	positive regulation of t cell mediated immunity	GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY	0.317696277595454	1.10373313471001	0.306044697218273	0.729049151335248	31	RSAD2,XCL1,HSPD1,HLA-B,PRKCZ,P2RX7,MALT1,ZP3,TNFSF4,HLA-E,IL12RB1,FOXP3,STX7,TRAF6,HLA-A
GO:0034067	protein localization to golgi apparatus	GO_PROTEIN_LOCALIZATION_TO_GOLGI_APPARATUS	0.33347544441272	1.10887719081084	0.306624617246374	0.729237783610581	26	RAB6A,VPS13A,VPS13D,OBSL1,GOLGA4,ARL1,GBF1,ATP9B,PAQR3,GOLPH3,PACS1,COG7,ARFRP1,VPS13C
GO:0006289	nucleotide excision repair	GO_NUCLEOTIDE_EXCISION_REPAIR	0.242865021506983	1.07607265748724	0.306680458581157	0.729237783610581	103	CUL4A,RPA4,RNF111,UBE2N,RAD23A,COPS6,COPS7A,ERCC1,GTF2H3,LIG3,EP300,COPS7B,POLD2,ERCC4,POLR2I,XAB2,RFC3,AQR,PRPF19,HMGN1,GTF2H5,HUS1,SUMO2,SUMO1,POLK,POLR2C,MMS19,FAN1,UBE2I,NEIL3
GO:0009612	response to mechanical stimulus	GO_RESPONSE_TO_MECHANICAL_STIMULUS	0.217178036669584	1.06168528129841	0.306773826973435	0.729237783610581	202	P2RY1,SHANK3,AGT,BAD,DENND5A,SUN1,NRXN1,HABP4,DENND5B,GLI2,RYR2,CLCN6,ATP1A2,DRD2,KCNJ2,PKD1L1,GJA1,HDAC4,BAG3,GSK3B,CAV3,TCAP,DMD,UCN,PSPH,SLC8A1,TGFBR2,CD40,TTN,PDE2A,SLC26A5,RAF1,PKD2L2,TNFRSF10B,CASP8AP2,MMP7,IRF1,KCNA5,LOXHD1,PTCH1,TIMP3,P2RX7,ETS1,CYBA,GADD45A,SOX9,PKD2L1,MKKS,NFKB1,HTT,ASNS,ENDOG,MAPK8,NFKBIA,HPN,PKD1L2,TLR4
GO:0048168	regulation of neuronal synaptic plasticity	GO_REGULATION_OF_NEURONAL_SYNAPTIC_PLASTICITY	0.288174378391133	1.0949603420114	0.307907979870597	0.731417261993245	46	SHANK3,AGT,DLG4,CAMK2A,DRD2,RASGRF1,GSK3B,RAB3GAP1
GO:1901617	organic hydroxy compound biosynthetic process	GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS	0.223477775528187	1.06549188800585	0.308569713342338	0.732472253251277	167	IDI2,CNBP,CHAT,LSS,LPIN1,TPH2,PCYT1A,SLC27A5,ACADM,CHPT1,HAND2,LCAT,TYR,PLA2G5,TMLHE,HMGCR,IMPA2,MVD,CYP27B1,CYP51A1,PRKAA2,ACER2,CYB5R1,CYP7B1,IP6K3,GGPS1,AGTR2,MSMO1,IPMK,INSIG1,PCYT1B,HMGCS2,PARK7,ACOT8,HMGCS1,SQLE,GOT1,PTAFR,CYP3A4,IDI1,SGMS1,FDFT1,SLC27A1,CHKA,SCP2,TYRP1,TH,NSDHL,APOA5,HSD17B3
GO:0046697	decidualization	GO_DECIDUALIZATION	0.358588964484784	1.11309780389642	0.30899333826795	0.732489779620529	20	PPARD,ESR1,GHSR,CYP27B1,STC2,DEDD
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.329542869795551	1.10611467838097	0.30901232533011	0.732489779620529	27	ANK2,CALM3,CACNA2D1,RYR2,S100A1,AKAP6,CALM1,HTT,TRDN,SUMO1,JPH2
GO:0010717	regulation of epithelial to mesenchymal transition	GO_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	-0.259669914029065	-1.08079264532814	0.30961855104281	0.73341030458135	60	VASN,TGFBR1,SFRP2,BMP2,FOXA1,CRB2,CTNNB1,TRIM62,BMP5,DAB2,SMAD2
GO:0040020	regulation of meiotic nuclear division	GO_REGULATION_OF_MEIOTIC_NUCLEAR_DIVISION	-0.31192672037295	-1.09915453705035	0.310140440119429	0.734095975050559	29	WNT5A,DMRT1,CALR,MSX2,FBXO5,CDC20,NPM2,MOS,NANOS2,FBXO43,RPS6KA2
GO:0046058	camp metabolic process	GO_CAMP_METABOLIC_PROCESS	0.320023651320385	1.10295465492092	0.310344198602776	0.734095975050559	30	PDE8B,PDE4C,ADCY7,ADCY5,PDE2A,ADCY8,ADCY9,ADCY4,PDE7A,PTH,ADM
GO:0036119	response to platelet derived growth factor	GO_RESPONSE_TO_PLATELET_DERIVED_GROWTH_FACTOR	-0.356534511919068	-1.10720147841229	0.311062953732799	0.734784397647035	18	HAS1,ERRFI1,CCNA2,PDGFD,CORO1B,FN1,IQGAP1,FER,CCL2,PDGFRB,YES1,DNMT1
GO:1903393	positive regulation of adherens junction organization	GO_POSITIVE_REGULATION_OF_ADHERENS_JUNCTION_ORGANIZATION	-0.341243307654399	-1.1047632769081	0.311071826098343	0.734784397647035	21	KDR,S100A10,ITGB1BP1
GO:0006972	hyperosmotic response	GO_HYPEROSMOTIC_RESPONSE	-0.35637446742295	-1.10670446761309	0.311799761620977	0.73598737560744	18	AQP1,ERRFI1,SST,HNMT,PDPK1,SLC6A12,RAC1,NTS,TLR3
GO:1990267	response to transition metal nanoparticle	GO_RESPONSE_TO_TRANSITION_METAL_NANOPARTICLE	-0.218337779830119	-1.05930601471969	0.31208375316409	0.736141494849564	143	ASS1,ATP13A2,SLC34A1,MT1M,KHK,LIPC,ALDOB,MT1E,AQP1,MT2A,TSPO,CRIP1,TAT,SNCA,MT1A,SLC30A2,CP,MT1F,SLC6A3,CPS1,EIF2AK3,ZACN,SLC31A1,CCNB1,SLC18A2,MT1G,KRT14,HMBS,SLC30A8,BAX,ADAM9,ATP7B,ABAT,MDM2
GO:0071478	cellular response to radiation	GO_CELLULAR_RESPONSE_TO_RADIATION	-0.222992355412826	-1.06099310959818	0.313101695743537	0.736149339711127	127	NOC2L,CNGB1,KDM1A,AQP1,SFRP2,POLH,SWI5,CRIP1,HIST3H2A,GNAT1,FIGNL1,TP73,KDM4D,CDKN1A,OPN1LW,HIF1A,YY1,MME,DDB2,ZBTB1,OPN3,EIF2AK4,XPC,AURKB,BAX,RS1,CDC25A,TRIAP1,MDM2,MYC,GNGT1,IFI16,SIRT1,XRCC5,PCNA
GO:0031670	cellular response to nutrient	GO_CELLULAR_RESPONSE_TO_NUTRIENT	-0.294877779690384	-1.08876657967194	0.313322368421053	0.736149339711127	35	CDKN2B,XBP1,PIM1,LEP,PPARG,MDM2,PAWR,ATP2B1,GAS6,HMOX1,FGF23,FOLR2,NR1H4,COL1A1,TNC,FOXA2
NA	nucleophagy	GO_NUCLEOPHAGY	0.374991685467244	1.11399217461538	0.31356940931409	0.736149339711127	17	WIPI2,ATG9A,WDR45,ATG3,ATG4D,ATG12,ATG2B,ATG4B,ATG9B
GO:1901987	regulation of cell cycle phase transition	GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.205031838149683	1.05211910263629	0.313772950937147	0.736149339711127	304	CUL4A,PPP2R5C,FOXN3,DDX3X,PCID2,CDC26,FBXW7,NPM1,CSNK2A1,PSMD11,APP,CREBBP,CCND1,PSMD2,PSMC6,TAOK3,MAD2L1,GOLGA2,C8orf4,PLAGL1,FZR1,KANK2,ZNF655,PKIA,BTRC,SMARCD3,PTEN,CDK5RAP3,ANAPC1,TFDP2,PSMC5,PSMB7,PSME4,CNOT6L,GORASP1,EZH2,CNOT4,FAM83D,DGKZ,EP300,FBXO31,MYO16,KCNA5,ANAPC11,ANKRD17,PSMA8,CDKN1B,CDK1,PSMD8,PSMB10,APC,PRPF19,HUS1,GADD45A,CDC25C,DLGAP5,CNOT8,ARID3A,RDX,PSMD3,CLSPN,PSMB1,GIGYF2,PSMA5,KLHL22,FOXO4,TPR,PSMB9,BID,PRKDC,MAD1L1,MRE11A,CTDSP2,ESPL1,CNOT1,CYP1A1,MAD2L1BP,RINT1,PRKCQ,PPP1R1C,PSMD6
GO:0008652	cellular amino acid biosynthetic process	GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS	-0.240964275573943	-1.07036542130111	0.314405790333878	0.736149339711127	84	ASS1,SHMT1,GPT2,GART,CARNS1,MTHFD1L,PYCR1,CPS1,PADI4,AGXT2,PSAT1,BCAT1,DHFR,GGT1,GADL1,AGXT,OAT,LGSN,ABAT,PYCR2,NOXRED1,MRI1,GOT1L1,GPT
GO:0006687	glycosphingolipid metabolic process	GO_GLYCOSPHINGOLIPID_METABOLIC_PROCESS	-0.258210890505442	-1.07787927403435	0.314463388329241	0.736149339711127	61	GAL3ST1,SMPD3,ARSF,ARSH,ITGB8,SMPD2,ARSI,ARSD,NEU1,NEU2,ST3GAL5,BAX,ARSK,CLN3,ARSE,UGT8,GBA3
GO:0016925	protein sumoylation	GO_PROTEIN_SUMOYLATION	0.241780949296115	1.07126941139762	0.314628049306094	0.736149339711127	103	HERC2,TRPM4,POM121,RANGAP1,NFATC2IP,NUP85,SP100,EYA1,RAE1,SENP5,SMC1A,SAE1,NUP188,INCENP,PIAS3,MITF,SUMO2,SUMO1,TPR,BCL11A,AAAS,RNF168,PIAS4,PCGF2,MTA1,UBE2I,POM121C,SCMH1,TOP2B,NUP214,WRN,NSMCE2,NUP35,CDKN2A,TRIM28,IFIH1,CBX8,RPA1,NUP93
GO:0001755	neural crest cell migration	GO_NEURAL_CREST_CELL_MIGRATION	-0.268322675329458	-1.07876214718633	0.315037151141718	0.736149339711127	51	SEMA3F,SEMA3C,GBX2,SEMA3A,SEMA3B,ACVR1,HIF1A,SEMA3D,GDNF,EDNRB,CORO1C,SEMA3E,SEMA4B,SEMA4A
GO:2000008	regulation of protein localization to cell surface	GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_SURFACE	0.338484583024051	1.10296148143755	0.315259346395618	0.736149339711127	24	GPM6B,NEDD4L,CAV3,STX4,ERBB4,TNF,GBF1,COMMD1,EGF,ACTN2,GPD1L
GO:0033059	cellular pigmentation	GO_CELLULAR_PIGMENTATION	-0.283332137295143	-1.08527608703455	0.315263653062139	0.736149339711127	41	RAB27B,PMEL,BBS7,RAB38,GPR143,VPS33A,POMC,RAB17,SHROOM2,SNAPIN,RAB11A,BCL2,BLOC1S3,AP1M1,ASIP
GO:0045055	regulated exocytosis	GO_REGULATED_EXOCYTOSIS	-0.205710634990656	-1.05142173575193	0.315272819989801	0.736149339711127	205	MRGPRX2,SERPINA3,STX19,TIMP1,P2RX1,CCL3,SYT4,SNAP25,ANXA3,NLGN1,TMED10,RAB31,SYTL1,SYT17,TRIM9,POTEKP,SERPING1,MMRN1,RPH3A,C2CD4D,NR4A3,STXBP3,TMEM79,SNAP23,PCLO,STX11,SYT6,ORM1,CDK5,VAMP8,SPARC,UNC13B,SCIN,RARRES2,PROS1,LAT,HGF,F5,SYT5,STX2,STXBP1
GO:0021955	central nervous system neuron axonogenesis	GO_CENTRAL_NERVOUS_SYSTEM_NEURON_AXONOGENESIS	0.328074816556689	1.10118713970547	0.315348973499625	0.736149339711127	27	PAFAH1B1,GLI2,NFIB,ZEB2,PTEN,DCLK1,FBXO45,EPHA4
GO:0006688	glycosphingolipid biosynthetic process	GO_GLYCOSPHINGOLIPID_BIOSYNTHETIC_PROCESS	0.346800255479847	1.10463662814177	0.315773968441016	0.736149339711127	22	ST6GALNAC4,ST8SIA6,ST3GAL6,ST3GAL3,ST3GAL2,ST6GALNAC3
GO:0050433	regulation of catecholamine secretion	GO_REGULATION_OF_CATECHOLAMINE_SECRETION	0.294194162643057	1.09004164382747	0.315787572254335	0.736149339711127	41	P2RY1,AGT,DRD2,OPRK1,ADRA2C,PINK1,STX1A,SNCG,GCK,AGTR2
GO:0019369	arachidonic acid metabolic process	GO_ARACHIDONIC_ACID_METABOLIC_PROCESS	-0.271011364187046	-1.08068782629708	0.315794217725398	0.736149339711127	49	PTGIS,SSTR4,CYP2C9,ALOX15,ALOX12B,TBXAS1,AKR1C3,DAGLA,CYP4F2,PTGS1,CYP1A2
GO:1902751	positive regulation of cell cycle g2 m phase transition	GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.374297570494529	1.11193015916849	0.315801220056539	0.736149339711127	17	NPM1,APP,CCND1,SMARCD3
GO:0006783	heme biosynthetic process	GO_HEME_BIOSYNTHETIC_PROCESS	0.356383576249657	1.10625204721011	0.316136195410807	0.736149339711127	20	COX15,ATPIF1,COX10,ALAD,FXN,NFE2L1,SLC25A38,FECH,SLC25A39
GO:0034504	protein localization to nucleus	GO_PROTEIN_LOCALIZATION_TO_NUCLEUS	0.228035775549325	1.06434477356147	0.316141871721788	0.736149339711127	144	OR1D2,AGT,ADAR,PIK3R1,SUN1,PAF1,PRICKLE1,RANBP6,TSC2,NUP85,RERE,RAE1,POLA2,JAK2,PIKFYVE,SIX1,SHH,NUP188,TNF,IPO8,MAPK1,CBLB,KPNA4,KPNA3,SOX9,SYNE2,SUMO1,TPR,BCL6,KPNA6,NFKBIA,EGF,TGFB3,MSX1,TNPO3,WRAP53,SUPT7L,ZBTB16,TAF3,SPTBN1,MT3,CTDNEP1,JAK3,NUP214,SMO,SIX2,RBM22,NCKIPSD,NR5A1,KPNB1,MCM3AP,RPL11,NUP35,IPO7,PDIA3
GO:0042439	ethanolamine containing compound metabolic process	GO_ETHANOLAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.241803131381799	-1.06888336057263	0.316369666254058	0.736149339711127	82	SMPDL3B,PLA2G2A,CHDH,APOA2,SMPD3,LIPC,BCHE,FGF7,PEMT,SMPDL3A,PLA2G16,SMPD2,PLA2G2D
GO:0048284	organelle fusion	GO_ORGANELLE_FUSION	0.237911150971482	1.06894104509689	0.316461109495544	0.736149339711127	112	C2CD4A,DYSF,SYT9,VCPIP1,MFN2,USP30,SYT8,VPS4A,SYTL2,VAMP2,MFN1,STX1A,SYT7,VPS11,WIPI2,VTI1A,VPS39,STX4,SEC22C,SYT12,CDK1,SYTL3,PLD6,VAMP1,RPH3AL,GOSR1,TMEM175,C2CD4B,OPA1,UVRAG,TSG101,BAK1,STX10,DOC2B,LRMP,SYTL4
GO:0043279	response to alkaloid	GO_RESPONSE_TO_ALKALOID	-0.222194798731079	-1.05880229097236	0.317053525664494	0.736743842653832	128	SLC34A1,CNR1,DRD5,NKX6-1,TMED10,BCHE,RYR1,SNCA,OPRM1,TACR1,HTR3A,DDC,SLC6A3,STAR,HIF1A,DHX15,HTR1B,CASP3,CHRNB2,SLC18A2,CDK5,PPARG,RAPGEF3,CCNA2,RYR3,KCNK1,CHRNG
GO:0002704	negative regulation of leukocyte mediated immunity	GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.290582618332511	1.08853425414603	0.317154434939217	0.736743842653832	43	XCL1,SPN,CEACAM1,ABR,CD300A,HLA-B,CR1,CCR2,MICA,LILRB1,BCL6,FOXJ1,JAK3,HLA-E,TAP1,SUSD4,FOXP3,PPP3CB
NA	rna 3 end processing	GO_RNA_3_END_PROCESSING	0.24708499002103	1.07179692162302	0.317612738543819	0.737299639957583	91	ELAC2,PAF1,NCBP1,APP,ZCCHC11,WDR33,EXOSC4,EXOSC7,TUT1,CLP1,DDX39B,SRSF4,LIN28B,CPSF1,SYMPK,NCBP2,RNPS1,EXOSC3,SRSF1,PAPOLG
GO:0061053	somite development	GO_SOMITE_DEVELOPMENT	-0.247086236410307	-1.07188286871934	0.318045931728118	0.737796420535385	74	SEMA3C,TBX6,WNT5A,SFRP2,T,TMED2,FOXF1,SOX11,CRB2,COBL,PLXNA2,NLE1,WDR19
GO:0021575	hindbrain morphogenesis	GO_HINDBRAIN_MORPHOGENESIS	0.297154615744186	1.08885974973125	0.318663244650087	0.738056481321158	39	HERC1,ATP7A,NRXN1,DLC1,LRP6,GLI2
GO:1903010	regulation of bone development	GO_REGULATION_OF_BONE_DEVELOPMENT	-0.367569728352659	-1.10445453916349	0.319068337770851	0.738056481321158	16	TNFSF11,TJP2,SLC9B2,CLDN18
GO:0055067	monovalent inorganic cation homeostasis	GO_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS	-0.226536812790536	-1.06039659988785	0.319473887068799	0.738056481321158	114	SGK2,MC3R,SLC26A9,CFTR,SCNN1A,ATP6V1C2,TMPRSS3,SLC9A7,ATP6V1B1,SLC4A4,SGK1,RAB38,ATP6V0D1,ATP6V1H,SLC17A7
GO:0060445	branching involved in salivary gland morphogenesis	GO_BRANCHING_INVOLVED_IN_SALIVARY_GLAND_MORPHOGENESIS	-0.367372667767897	-1.10386242169423	0.319717730588566	0.738056481321158	16	SEMA3C,FGF7,FGFR2,SEMA3A
GO:0050926	regulation of positive chemotaxis	GO_REGULATION_OF_POSITIVE_CHEMOTAXIS	-0.334494998857091	-1.09662552276919	0.319887942920925	0.738056481321158	22	IL16,SCG2,KDR,F7,ARTN
GO:0006063	uronic acid metabolic process	GO_URONIC_ACID_METABOLIC_PROCESS	0.379227978902985	1.10807951376277	0.320397732552737	0.738056481321158	16	UGT2A3,UGT3A1,CRYL1,UGT3A2
GO:0032418	lysosome localization	GO_LYSOSOME_LOCALIZATION	-0.338788630032581	-1.09681634393563	0.320456579148388	0.738056481321158	21	MRGPRX2,NR4A3,SNAP23,VPS33A,LAT
GO:0031060	regulation of histone methylation	GO_REGULATION_OF_HISTONE_METHYLATION	0.281394631946558	1.08380925455855	0.320575280898876	0.738056481321158	49	TET1,SMARCB1,JARID2,ZNF304,PAF1,MTHFR,EED,NSD1
GO:0048670	regulation of collateral sprouting	GO_REGULATION_OF_COLLATERAL_SPROUTING	-0.36003232123129	-1.10108837003783	0.320608210407925	0.738056481321158	17	ULK2,EFNA5,RND2,FGF13,FSTL4,WNT3,CRABP2,SPP1
NA	regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity	GO_REGULATION_OF_ALPHA_AMINO_3_HYDROXY_5_METHYL_4_ISOXAZOLE_PROPIONATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY	0.36648135334461	1.10567117571658	0.321406688081401	0.738056481321158	18	SHANK3,NLGN3,NRXN1,SHANK1
GO:0001759	organ induction	GO_ORGAN_INDUCTION	-0.366873729766995	-1.10236323855331	0.32153603047817	0.738056481321158	16	BMP4,BMP2,WNT2B,CTNNB1,GDNF
GO:0021544	subpallium development	GO_SUBPALLIUM_DEVELOPMENT	0.350110914148479	1.10193392813008	0.321539966410129	0.738056481321158	21	SHANK3,DRD2,OGDH,MKKS,DLX2,FGF8,ASCL1,RARB,BBS2
GO:0021537	telencephalon development	GO_TELENCEPHALON_DEVELOPMENT	-0.203375854763888	-1.0463356007698	0.32155241055146	0.738056481321158	216	CCDC85C,PHLPP2,DLX1,ANXA3,RARA,CDON,AQP1,ID4,BMP4,WNT5A,BMP2,RFX4,GART,LPAR1,RTN4,SEMA3A,FUT10,LHX5,SLC38A2,POU3F2,NRGN,POU3F3,CTNNB1,SLIT3,GNG12,FEZF1,NR4A3,UBA6,EGFR,HIF1A,ROBO2,LRP8,EMX1,CASP3,CDK5,HTR5A,FGF13,EXT1,LMX1A,FAS,KCNA1,SLC8A3,ARL13B,BAX
GO:2000725	regulation of cardiac muscle cell differentiation	GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION	0.36638111381046	1.10536875388102	0.321629500343502	0.738056481321158	18	PRICKLE1,PIN1,AKAP6,CAV3,DDX39B,MTOR,MEF2C,MYOCD,DKK1,EFNB2
GO:0044089	positive regulation of cellular component biogenesis	GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS	-0.189581709112471	-1.03805832861485	0.32165543258162	0.738056481321158	368	MMP1,PRKCA,HAP1,BBC3,LRRN1,SLITRK2,EPS8L1,CCL19,ARHGEF5,NLGN1,KDR,AGRN,FLRT3,TGFBR1,S100A10,GPM6A,SLITRK4,CTGF,RPA3,BAIAP2L2,LRRC4B,MPP7,ALOX15,EFNA5,SDC1,LPAR1,CBLN2,ITGB1BP1,ARPC5,TPBG,TACR1,FLRT2,CNOT6,SRPX2,EVL,ACTR3,COBL,KIRREL,WNT10B,CTNNB1,NPHS1,PYCARD,CCL21,SH3GLB1,FLRT1,RAB3GAP2,CLSTN3,BAIAP2,PIEZO1,RPA2,GTF2H2,STX18,RHOQ,DPYSL3,RPS3,TPM1,UNC13B,DDB2,CDC42EP1,SCIN,RAPGEF3,PPM1E,MAGI2,AMIGO2
GO:0032104	regulation of response to extracellular stimulus	GO_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS	0.223519822157347	1.05984058540096	0.321798497347769	0.738056481321158	161	LRSAM1,WDFY3,PARL,FBXW7,UBQLN4,ADRB2,PPARA,ULK1,LRRK2,CALCOCO2,TSC1,GHSR,RAB12,PINK1,KANK2,CAPNS1,RAB1B,CYP27B1,PRKAA2,RAB3GAP1,UCN,PIP4K2C,ATP6V0E2,PIKFYVE,KAT2A,TRIM13,PIP4K2B,SCOC,MTOR,PARK7,HDAC6,TRIM24,NPY,ATP6V0D2,VDAC1,USP36
GO:0032105	negative regulation of response to extracellular stimulus	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS	0.314144160542072	1.09139245096055	0.32188559553757	0.738056481321158	31	UBQLN4,PPARA,LRRK2,TSC1,PINK1,KANK2,UCN,MTOR,NPC1,MKKS,NPFF,GCG,CHMP4B,BBS2
GO:0051304	chromosome separation	GO_CHROMOSOME_SEPARATION	0.378702873505158	1.10654518990939	0.32218195335006	0.738233121154733	16	TEX11,ERCC4,RECQL5,NCAPD3,HFM1,ESPL1,DIS3L2,TOP2B,MLH1,NCAPD2,PPP2R1A
GO:0035725	sodium ion transmembrane transport	GO_SODIUM_ION_TRANSMEMBRANE_TRANSPORT	-0.241537270324143	-1.06577435380581	0.322685120462277	0.738425333649214	81	SCN4A,SLC34A1,SLC24A3,SCNN1A,SCN3B,SLC9A7,ANO6,SLC4A4,ABCB11,SLC17A2,SLC17A7,KCNK1,SCNN1G,SCNN1B,SLC8A3,PKD2,SHROOM2,SLC9A3,SLC3A2,ATP4A,SLC13A4,SLC20A1,ATP1B1,HCN2,ATP1A1
GO:0048678	response to axon injury	GO_RESPONSE_TO_AXON_INJURY	0.28689032901045	1.08512754566316	0.322893993632063	0.738425333649214	45	TXN2,RANGAP1,DRD2,MAX,MTR,LAMB2,GIPR,CTNNA1,JAK2,RXRA,CDK1,SOD1
GO:0008202	steroid metabolic process	GO_STEROID_METABOLIC_PROCESS	0.213438414415369	1.05365493042206	0.323046983597442	0.738425333649214	218	NR1I2,IDI2,CNBP,LRP5,LSS,CYP4V2,SULT1A2,PPARD,HSD17B8,CYP2D6,STAT5B,SLC27A5,CUBN,CYP2E1,APP,HSD11B2,VLDLR,ESR1,LDLR,CYP17A1,LCAT,PCSK9,CYP2B6,CEL,HMGCR,MVD,CYP27B1,CYP51A1,PRKAA2,CYB5R1,CYP7B1,CLN8,MBTPS1,GGPS1,MSMO1,SHH,INSIG1,IL4,HMGCS2,RXRA,ACOT8,CELA3A,HMGCS1,SQLE,FDX1,NPC1,CETP,SLCO1B1,CYP3A4,UGT2B11,IDI1,ATP8B1,APOL1,APOL2,FDFT1,TNFSF4,MED1,CYP1A1,SCP2,NSDHL,ADM,APOA5,OSBPL1A,HSD17B3
GO:0000469	cleavage involved in rrna processing	GO_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING	0.365922615898637	1.10398546951852	0.323170618489704	0.738425333649214	18	NOL9,ABT1,EXOSC7,RCL1,EXOSC3
GO:0007179	transforming growth factor beta receptor signaling pathway	GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY	-0.237022025367024	-1.0633694996939	0.323362727807172	0.738425333649214	89	CGN,GDF5,AMHR2,TGFBR1,FMOD,SKIL,GDF10,ACVR1,FUT8,LEFTY1,UBA52,MSTN,SMAD2,HPGD,LTBP2,ADAM9,F11R,RHOA,NODAL,FSHB,UBB,USP9Y,EID2
GO:0034614	cellular response to reactive oxygen species	GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES	0.241918866637991	1.06653070240388	0.32445165409771	0.74040967301213	100	ATP7A,HDAC2,IL18BP,GUCY1B3,MTR,PPIF,GSK3B,PTPRK,SLC8A1,EZH2,PPP5C,PXN,EP300,SETX,FOXO1,PRDX2,SOD2,PARK7,HDAC6,CDK1,ETS1,SOD1,TPO,CCS,IMPACT,FXN,PCGF2,ROMO1,PRDX3,TRPC6,PRDX5,AIFM1,MT3,SOD3,BNIP3,ARG1
GO:0090102	cochlea development	GO_COCHLEA_DEVELOPMENT	0.295947565089433	1.08443676989446	0.325097599768652	0.741381111667537	39	ZEB1,DVL2,PAFAH1B1,GLI2,EYA1,SIX1,SLC26A5,SOX9,HEY2,HPN,POU3F4,NTRK3
GO:0006555	methionine metabolic process	GO_METHIONINE_METABOLIC_PROCESS	0.37146181935095	1.1035059601648	0.325379407826216	0.741521385743429	17	MTR,MTHFR,EIF2B4,SMS,BHMT,MTRR,GNMT,ENOPH1,BHMT2,MSRA,MTHFD2L
GO:0021795	cerebral cortex cell migration	GO_CEREBRAL_CORTEX_CELL_MIGRATION	-0.282997237755001	-1.0776467913937	0.326315789473684	0.742041740365312	40	RTN4,SEMA3A,FUT10,POU3F2,POU3F3,CTNNB1,EGFR,CDK5,FGF13
GO:0046461	neutral lipid catabolic process	GO_NEUTRAL_LIPID_CATABOLIC_PROCESS	-0.316855453216188	-1.08602802344111	0.326419286012802	0.742041740365312	26	APOA2,LIPC,DAGLA,LPL,FABP2,CPS1,FABP4,LIPE,FABP1
GO:1904037	positive regulation of epithelial cell apoptotic process	GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS	-0.332835072926297	-1.09118353664732	0.326497559694469	0.742041740365312	22	BMP4,ANO6,PRKCI,XBP1,AKR1C3
GO:0035329	hippo signaling	GO_HIPPO_SIGNALING	0.325337488435269	1.09199926434187	0.326557148874604	0.742041740365312	27	AMOT,DVL2,YAP1,TEAD2,LATS1,AMOTL1,FAT4
GO:0070167	regulation of biomineral tissue development	GO_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT	-0.249577233369202	-1.06776714038458	0.326709999768685	0.742041740365312	69	MATN1,WNT6,CCL3,OSR1,BMP4,BMP2,ANO6,ACVR1,WNT10B,BMPR1B,MMP20,HIF1A
GO:0043162	ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway	GO_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS_VIA_THE_MULTIVESICULAR_BODY_SORTING_PATHWAY	-0.365137656407155	-1.09714677496914	0.327488797973894	0.743200963739998	16	TOM1L1,VPS25,SNF8,RNF126
GO:0070266	necroptotic process	GO_NECROPTOTIC_PROCESS	-0.341308954965899	-1.0906741319329	0.327661981637004	0.743200963739998	20	PYGL,LY96,RIPK1,RIPK3,FAS
GO:0021952	central nervous system projection neuron axonogenesis	GO_CENTRAL_NERVOUS_SYSTEM_PROJECTION_NEURON_AXONOGENESIS	0.343207227443724	1.09319202764933	0.329086188801532	0.745001871729823	22	PAFAH1B1,GLI2,NFIB,ZEB2,DCLK1,FBXO45,EPHA4
GO:0010810	regulation of cell substrate adhesion	GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION	-0.212569499030895	-1.04970832130153	0.32926617131781	0.745001871729823	161	VTN,CCL28,ITGA3,CCDC80,KDR,S100A10,NPNT,HOXA7,SPOCK1,ALOX15,EFNA5,ADAM15,FOXF1,NPY2R,ITGB1BP1,CYR61,DMP1,CALR,SPOCK2,MEN1,CCL21,CSF1,ABI3BP,RHOD,TRIOBP
GO:0014912	negative regulation of smooth muscle cell migration	GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION	0.376421716082115	1.09987979613899	0.329839234271908	0.745001871729823	16	PPARD,NDRG4,IGFBP3
GO:0030851	granulocyte differentiation	GO_GRANULOCYTE_DIFFERENTIATION	-0.371867359431474	-1.09550905476286	0.330065147284808	0.745001871729823	15	KDM1A,CEBPA,L3MBTL3,NKAP,IL25
GO:1902176	negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway	GO_NEGATIVE_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.358082156366145	1.09577340445137	0.330146023274776	0.745001871729823	19	TRAP1,PINK1,SOD2,PARK7,HSPB1,NME5,VNN1,HSPH1
GO:0071285	cellular response to lithium ion	GO_CELLULAR_RESPONSE_TO_LITHIUM_ION	-0.364350591835005	-1.09478184398523	0.330151308526528	0.745001871729823	16	CALR,SLC18A1,CTNNB1,CEBPA,FABP4,FAS,CDH1
GO:0046689	response to mercury ion	GO_RESPONSE_TO_MERCURY_ION	-0.371666867731163	-1.09491841278387	0.330627881306409	0.745001871729823	15	SLC34A1,AQP1,TAT
GO:0006622	protein targeting to lysosome	GO_PROTEIN_TARGETING_TO_LYSOSOME	-0.371622551588329	-1.09478785887932	0.33071445577127	0.745001871729823	15	AP3M1,SORL1,GCC2,SNX16,HGS,GNPTG,NAGPA,SCARB2
GO:0051769	regulation of nitric oxide synthase biosynthetic process	GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_BIOSYNTHETIC_PROCESS	-0.357207300883701	-1.09244859836618	0.330860405761993	0.745001871729823	17	KDR,NAMPT,TLR9,TLR2,EDN1,PTGER4
GO:0016054	organic acid catabolic process	GO_ORGANIC_ACID_CATABOLIC_PROCESS	0.217205317277537	1.05162348067681	0.330871149387214	0.745001871729823	188	SLC25A17,DECR1,IVD,PPARD,LPIN1,ACOX3,HIBCH,ACAD9,MCCC2,ACADM,DDO,AMT,MMAA,AUH,ALDH7A1,ACAD10,PPAT,CRYL1,OTC,DLD,RENBP,THNSL2,OGDH,CEL,HAAO,ASRGL1,PLA2G15,IDO1,HADH,ACAT1,ECI2,GLUD1,GOT2,ETFA,PEX7,ACOT8,HADHB,NAGK,PCCB,PRODH2,ECHS1,GOT1,BCKDK,HOGA1,GCDH,ACADVL,PCCA,DBT,GLUD2,HADHA
GO:0002724	regulation of t cell cytokine production	GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION	0.342736376273923	1.09169226102475	0.330890611478338	0.745001871729823	22	TRPM4,RSAD2,XCL1,PRKCZ,MALT1,CLC,TNFSF4
GO:0032786	positive regulation of dna templated transcription elongation	GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION	0.352430707600764	1.09398192780335	0.331310140636565	0.745405970149254	20	ELL3,PAF1,ELL,DDX39B,HMGN1,GTF2F2
GO:0002011	morphogenesis of an epithelial sheet	GO_MORPHOGENESIS_OF_AN_EPITHELIAL_SHEET	-0.283550295801728	-1.07366504193617	0.331691811792094	0.745405970149254	39	FLRT3,WNT5A,CYR61,SOX11,TOR1A,MMP12,MSX2,MPP5,SCNN1B,RHOA,PDCD10,WNT7A,RHOC,DDR1
GO:0030166	proteoglycan biosynthetic process	GO_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS	-0.261157536297406	-1.06707546177404	0.331968518265775	0.745405970149254	55	LIPC,B3GALT6,HS6ST3,EXTL2,BMPR1B,CHST8,NDST3,GAL3ST4,EXT1,HS3ST5,DCN,EXTL1,CHST3,B3GAT1,DSEL,CYTL1
GO:0007141	male meiosis i	GO_MALE_MEIOSIS_I	0.375677612485281	1.09770557377767	0.332143852801784	0.745405970149254	16	DMC1,SPO11,CCNA1,DMRTC2,UBR2,BRCA2,MEI1,BRDT,ING2,HSPA2
GO:0060512	prostate gland morphogenesis	GO_PROSTATE_GLAND_MORPHOGENESIS	-0.327533071442051	-1.08636943270859	0.332177348551361	0.745405970149254	23	ID4,BMP4,FGFR2,FOXA1,CRIP1
GO:0002237	response to molecule of bacterial origin	GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN	-0.193932824132575	-1.03725639531974	0.332709080207609	0.745411712730481	297	TNFRSF8,ASS1,SLPI,CNR1,CCL3,BDKRB1,RARA,IL18,WNT5A,TNFRSF21,ALPL,TNFRSF11B,ENTPD2,MGST1,LY96,CEBPB,TG,TSPO,SNCA,OPRM1,SOCS1,IRAK1,XBP1,CXCL1,CNR2,GNG12,PYCARD,RIPK2,CHUK,STAR,HIF1A,CPS1,TNFRSF1A,IRAK3,CASP3,LILRB2,C5AR1,SPARC,ABCA1,PTGER2,TNFRSF25,NR1H3,EDNRB,IL24,PROS1,FAS,NLRP3,TLR9,CYP1A2,DCN,IFNAR1,ATP4B,ADAM9,HMGB2,F2R,TLR2,EDN1,JUNB,CEBPE,ELANE,PTGER4,TRIB1,F3,CXCL5,ABL1,SOCS3,PAWR,CARD9,HNRNPA0,PF4,TIMP4,IL10,PLA2G4A,THBD,PTGFR
NA	negative regulation of cyclic nucleotide metabolic process	GO_NEGATIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS	-0.279989403089629	-1.07247207004872	0.332803189821245	0.745411712730481	41	PRKCA,SSTR4,APLP1,GABBR2,LPAR1,NPY2R,OPRM1,HTR1B,EDNRB,EDN1,GRM2,HPCA,GRM8,PALM,GRM3,GPR87,CRHR2,PDZD3
GO:0003279	cardiac septum development	GO_CARDIAC_SEPTUM_DEVELOPMENT	-0.241720587142419	-1.06121072198067	0.332844267449172	0.745411712730481	79	C5orf42,LRP2,RARA,BMP4,WNT5A,GATA3,PTK7,FGFR2,CYR61,SOX11,ACVR1,PARVA,MSX2
GO:0042220	response to cocaine	GO_RESPONSE_TO_COCAINE	-0.274135593697348	-1.07236633086298	0.333656076197339	0.746640353042414	45	CNR1,DRD5,SNCA,OPRM1,HTR3A,SLC6A3,HTR1B,CHRNB2,SLC18A2,CDK5,CCNA2,HNMT,BAX,ABAT,MDM2
GO:0033045	regulation of sister chromatid segregation	GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION	0.267639652491609	1.07108087263222	0.334222886421862	0.746640353042414	59	PCID2,CDC26,CSNK2A1,MAD2L1,GOLGA2,PTEN,GORASP1,ANAPC11,APC,DLGAP5,SFPQ,ATRX,KLHL22,TPR,MAD1L1,ESPL1
GO:1901988	negative regulation of cell cycle phase transition	GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.227897145038673	1.05538451639087	0.334409547313973	0.746640353042414	136	PPP2R5C,FOXN3,NPM1,CSNK2A1,CCND1,TAOK3,MAD2L1,PLAGL1,KANK2,ZNF655,PTEN,CDK5RAP3,TFDP2,CNOT6L,EZH2,CNOT4,DGKZ,EP300,FBXO31,MYO16,CDKN1B,CDK1,APC,PRPF19,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,CLSPN,GIGYF2,KLHL22,FOXO4,TPR,PRKDC,MAD1L1,MRE11A,CTDSP2,CNOT1
GO:0033003	regulation of mast cell activation	GO_REGULATION_OF_MAST_CELL_ACTIVATION	-0.286955197262431	-1.0732720600934	0.3344130459064	0.746640353042414	37	CNR1,FOXF1,CNR2,NR4A3,VAMP8,PDPK1,FCER1A,IL4R,ZAP70,IL13RA2,SNX6,FES,HMOX1,VAMP7,FER,C12orf4,STXBP2,CD226,CD84
GO:0010720	positive regulation of cell development	GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT	-0.185030376730557	-1.03137336582205	0.334661012092384	0.746640353042414	443	GDF5,BEND6,HAP1,TCF3,CNR1,SYT4,ITGA3,TNFSF11,PAX8,UFL1,NKX6-1,NLGN1,RARA,SPINT1,CDON,SNW1,GDPD5,PRKD1,BMP4,WNT5A,S100A10,CUL7,BMP2,MMD,KATNB1,NEUROG1,PTK7,PRKCI,SYT17,MAP2K2,EFNA5,LPAR1,SGK1,FOXA1,SOX11,TLE6,SKIL,CRB2,TSPO,OPRM1,CALR,SEMA3A,PRMT5,CLCF1,PLXNB2,COBL,CTNNB1,TP73,FEZF1,IL6ST,CSF1,STAR,HIF1A,ROBO2,BAIAP2,LRP8,TRIOBP,ADIPOQ,BMP5,FZD3,DAB2,MAG,DUOXA1,SMAD2,INPP5E,DPYSL3,KCTD11,PPARG,RND2,NEU1,CDH4,MAGI2,PAK3,GDNF,LTK,SEZ6,RNF112,HGF,CPNE6,SLC9B2,IL5,XRCC2,MYOD1,ADCYAP1,TIMP2,BAX
GO:0044030	regulation of dna methylation	GO_REGULATION_OF_DNA_METHYLATION	-0.36290982793552	-1.09045271101833	0.334848583241336	0.746640353042414	16	GRHL2,PRMT5,MBD3,PRDM14,H1FOO
GO:0021895	cerebral cortex neuron differentiation	GO_CEREBRAL_CORTEX_NEURON_DIFFERENTIATION	-0.330854445201823	-1.08469014535244	0.334945612921582	0.746640353042414	22	DLX1,GDPD5,ID4,EMX1,PSEN1,CHD5,RAC1
GO:0006940	regulation of smooth muscle contraction	GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION	0.269748548902567	1.0719152861526	0.335366723744292	0.746874022214449	57	FLT1,ADRB2,ATP1A2,GHSR,ADRA2C,TACR3,GUCY1A3,PLCE1,DOCK4,TNNI3,ADA,DAPK3,SOD1,CHRM2,NMUR2,ADORA2B,PTAFR
GO:0021954	central nervous system neuron development	GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT	0.260713026089338	1.06807627855729	0.335494213187239	0.746874022214449	66	NRP1,ATP7A,PAFAH1B1,GLI2,DRD2,NFIB,ZEB2,OGDH,RAPGEF2,PTEN,DCLK1,SLC4A10,FGFR1,FBXO45,NPY,EPHA4,FGF8,UQCRQ,PLXNA3,DCLK2,GATA2
GO:0032332	positive regulation of chondrocyte differentiation	GO_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION	-0.34435743780731	-1.08457235878955	0.33624397237065	0.747798229578467	19	GDF5,FGF18,BMPR1B,SOX6
GO:0098743	cell aggregation	GO_CELL_AGGREGATION	-0.344269922748909	-1.08429672538397	0.336591511360181	0.747798229578467	19	CTGF,BMPR1B,FGF4,MYCN,MGP,WNT7A,COL11A1,UNCX,MYF5
GO:0042417	dopamine metabolic process	GO_DOPAMINE_METABOLIC_PROCESS	-0.326432115957909	-1.08271775753735	0.336720807726075	0.747798229578467	23	NPR1,SNCAIP,SNCA,GRIN2A,DDC,SLC6A3
GO:0060119	inner ear receptor cell development	GO_INNER_EAR_RECEPTOR_CELL_DEVELOPMENT	-0.294878504883989	-1.07310581214184	0.336798014272417	0.747798229578467	33	PDZD7,LRTOMT,GRXCR1,ATP2B2,USH1G
GO:0007249	i kappab kinase nf kappab signaling	GO_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING	-0.251298532754044	-1.06181638273616	0.337153154818289	0.748093288805775	65	TNFSF14,LY96,RIPK2,RIPK1,CHUK,TRADD,UBA52,RIPK3,TNFRSF1A,IKBKG,ZNF675,NLRP12,TLR9,TLR2,UBB,IKBKE,CARD9,IRAK1BP1,TAB2,TLR3,AVPR2,TRIP6
GO:0007163	establishment or maintenance of cell polarity	GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY	-0.218496381740858	-1.04804155452227	0.338001662022779	0.74867830688491	133	KIF2C,EZR,PARD6B,CCL19,CYP26B1,AQP1,WNT5A,WWC1,PTK7,PRKCI,MPP7,FOXF1,FRMD4B,CRB2,ACTR3,PDZD11,PARVA,BRSK2,CCL21,DLG5,WNT7B,RAB10,WDR43,MPP5,LIN7B,FGF13,FERMT1,DOCK7,MSN,FBF1,CCL4,ZW10,CDC42,LLGL1,SFRP5,MOS,DLG1,SIPA1L3,RICTOR,WNT7A,ARF4,NDC80,RAB11FIP2,LLGL2,FSCN1,PARD3,DYNLT1
GO:0009069	serine family amino acid metabolic process	GO_SERINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS	-0.289940409597692	-1.07053650633769	0.338437944523471	0.74867830688491	35	SHMT1,GART,TDH,GLYAT,AGXT2,PSAT1,DHFR,GGT1,AGXT,MRI1,GLDC,SRR,AHCYL1,DAO,GCSH,GCLM
GO:0042752	regulation of circadian rhythm	GO_REGULATION_OF_CIRCADIAN_RHYTHM	0.242841471024626	1.05960787614069	0.338559894660245	0.74867830688491	94	OPRL1,NR2F6,DRD4,PPARA,ROCK2,DRD2,SUV39H1,ZFHX3,USP2,BTRC,PRKAA2,EZH2,NPS,PTGDS,ADA,THRAP3,CREB1,SFPQ,MAGED1,PPP1CB,PRKDC,MAPK8,MTA1,HCRTR1,PROX1,PSPC1,PER1,PER3,UTS2,SIN3A,PPARGC1A,UBE3A,PPP1CC,DRD3,CRY2,GNA11
GO:0050808	synapse organization	GO_SYNAPSE_ORGANIZATION	0.226928179381075	1.05318693501428	0.338693059942237	0.74867830688491	138	SHANK3,NLGN3,LRRTM2,IL1RAPL1,DNER,NRXN1,DLG4,APP,ALS2,LRRK2,PIN1,TSC1,SHANK1,CACNA2D2,MUSK,DRD2,CDH2,LAMB2,CEL,PDZRN3,SNCG,PTEN,NFASC,DNAJA3,DNM3,SNCB,DRP2,DBNL,FBXO45
GO:0032787	monocarboxylic acid metabolic process	GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS	0.19441845939246	1.03730175647533	0.338945108862312	0.74867830688491	451	SLC25A17,UGT2A3,DECR1,IVD,CYP4V2,PPARD,LPIN1,HSD17B8,CYP2D6,DLAT,ACOX3,MAPKAPK2,STAT5B,SLC27A5,OGDHL,ACAD9,NDUFAB1,CYP2E1,MCCC2,ACADM,DDO,AMT,PPARA,MMAA,UGT3A1,ACAD10,CRYL1,ACSM2A,HAGH,ACOT2,FADS1,PLA2G4C,PTGR2,DLD,PGAM2,PGAM1,LIPT2,PRKAB2,THNSL2,PLA2G5,CYP2B6,OGDH,QKI,CEL,HAAO,UGT3A2,DHTKD1,TMLHE,NDUFS6,ABCC1,PDHA1,LIAS,PRKAA2,ACOT11,CYP7B1,ECHDC2,PFKM,ADIPOR2,ACSF2,GCK,SLC5A6,PLA2G15,MGLL,IDO1,MSMO1,EGLN1,HADH,CYP2F1,ELOVL6,PFKFB4,ECI2,PTGDS,IDH2,GOT2,PDHX,ETFA,PFKP,ALDOC,PEX7,SLC27A6,GGT7,PARK7,ADH7,ACOT8,HADHB,PDHB,ALDOA,HK3,PCCB,FABP3,NPC1,ECHS1,ENO2,GALK1,IDH1,SLCO1B1
GO:0048704	embryonic skeletal system morphogenesis	GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS	-0.234247349600308	-1.05473335952184	0.338976257279608	0.74867830688491	91	HOXA6,OSR1,IRX5,RDH10,TGFBR1,BMP4,HOXA3,HOXA7,WNT9A,GRHL2,FGFR2,SOX11,MTHFD1L,CTNNB1,WDR19,SMAD2,SPEF2,WNT9B,TULP3,HOXB8,NODAL,SLC39A1,MYCN,DLG1,AXIN1
GO:0015012	heparan sulfate proteoglycan biosynthetic process	GO_HEPARAN_SULFATE_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS	-0.329665239896784	-1.0807913938202	0.339169639535138	0.74867830688491	22	LIPC,B3GALT6,HS6ST3,EXTL2,NDST3,EXT1,HS3ST5,EXTL1
GO:0046173	polyol biosynthetic process	GO_POLYOL_BIOSYNTHETIC_PROCESS	0.328987496639212	1.08312642729609	0.339468903121616	0.74867830688491	25	IMPA2,CYP27B1,ACER2,IP6K3,IPMK,GOT1,PTAFR,CYP3A4,SCP2,ISYNA1
GO:0051952	regulation of amine transport	GO_REGULATION_OF_AMINE_TRANSPORT	0.257437623647885	1.06353946899944	0.339486709763788	0.74867830688491	69	P2RY1,AGT,DRD4,ATP1A2,DRD2,OPRK1,ADRA2C,SLC6A1,PINK1,STX1A,SNCG,RAB3GAP1,GCK,AGTR2
GO:0014059	regulation of dopamine secretion	GO_REGULATION_OF_DOPAMINE_SECRETION	-0.333875353934798	-1.08090978436249	0.339815360439992	0.74867830688491	21	CNR1,NPY2R,SNCA,SLC18A1,HTR1B,CHRNB2,GDNF,ABAT
GO:0030041	actin filament polymerization	GO_ACTIN_FILAMENT_POLYMERIZATION	-0.348802082820047	-1.08318877657293	0.339863473832485	0.74867830688491	18	COBLL1,WASF1,COBL
GO:0071398	cellular response to fatty acid	GO_CELLULAR_RESPONSE_TO_FATTY_ACID	-0.267957645863309	-1.06371629409027	0.341120021625518	0.750949626232854	48	ASS1,FFAR3,P2RY4,AKR1C3,DGAT2,CPS1,CCNB1,PPARG,PTGER2,EDN1,PTGER4,SMARCD1,PTGFR,ACACA
NA	protein complex localization	GO_PROTEIN_COMPLEX_LOCALIZATION	-0.265432856644004	-1.06306478025616	0.341534988713318	0.750949626232854	50	EZR,TRAF3IP1,IFT57,WDR35,SSX2IP,WDR19,TTC30B,MZT1,PCM1,TTC26,ZNF365,DYNLL1,IFT20,DLG1,EXOC3L4,DYNC2H1,RCC2,IFT140,RAN,SEH1L
GO:0065005	protein lipid complex assembly	GO_PROTEIN_LIPID_COMPLEX_ASSEMBLY	-0.337741627939899	-1.07927451510248	0.341717070623559	0.750949626232854	20	APOA2,APOC1,ABCA7,ABCA1,APOM
GO:1901568	fatty acid derivative metabolic process	GO_FATTY_ACID_DERIVATIVE_METABOLIC_PROCESS	-0.234368885618417	-1.05317123477045	0.341984300968814	0.750949626232854	90	PDPN,PTGIS,SSTR4,CYP2C9,ALOX15,ALOX12B,TBXAS1,AKR1C3,DAGLA,TNFRSF1A,PLA2G4F,HPGD,GGT1,PTGR1,CYP4F2,PTGS1,CYP1A2,MIF,EDN1,FCER1A,PLA2G4A,CYP1B1,ALOX5AP,ALOXE3,PTGES,GGT6,CYP2A7,CYP4F8,AKR1C2,FAAH,ALOX5,GPX1,DAGLB
GO:0071391	cellular response to estrogen stimulus	GO_CELLULAR_RESPONSE_TO_ESTROGEN_STIMULUS	-0.281610398422354	-1.06631960787379	0.342279625733089	0.750949626232854	39	SSTR3,RARA,SSTR2,EGFR,MSX2,CCNA2,SFR1,FAS,MYOD1,ZNF703,MDM2,PAWR,IL10,NRIP1,CCDC62
GO:0070229	negative regulation of lymphocyte apoptotic process	GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS	-0.31326993042269	-1.0737385766511	0.342366319864505	0.750949626232854	26	NOC2L,BMP4,SLC39A10,HIF1A,RAG1,AURKB,MIF,GPAM
GO:0070230	positive regulation of lymphocyte apoptotic process	GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS	-0.342831426625883	-1.07976610411093	0.342456231808506	0.750949626232854	19	BBC3,WNT5A,LGALS16,FAS,PRELID1,BAX
GO:0031663	lipopolysaccharide mediated signaling pathway	GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY	-0.301723171804013	-1.07219174414227	0.342836273489896	0.750950627853018	30	CCL3,IL18,LY96,IRAK1,RIPK2
GO:2000404	regulation of t cell migration	GO_REGULATION_OF_T_CELL_MIGRATION	-0.320641328296876	-1.07645882804868	0.342902886218089	0.750950627853018	24	WNT5A,TNFSF14,PYCARD,CCL21,RIPK3
GO:0072074	kidney mesenchyme development	GO_KIDNEY_MESENCHYME_DEVELOPMENT	-0.35354404878647	-1.08124525899103	0.34377298092313	0.752265584333529	17	OSR1,WT1,BMP4
GO:0007405	neuroblast proliferation	GO_NEUROBLAST_PROLIFERATION	-0.309821331229087	-1.07263011339561	0.343950307275491	0.752265584333529	27	ID4,FGFR2,PLXNB2,DAGLA,ARTN,RAB10,FGF13,KCNA1,DOCK7,NEUROD4
GO:0016311	dephosphorylation	GO_DEPHOSPHORYLATION	0.207505072153471	1.04254446461457	0.344475544841199	0.752617200642547	253	PTPRM,MTMR1,LPIN1,PTPRB,SSH2,ACP6,EYA4,PPM1L,PPP2R3A,DAPP1,PGAM2,PGAM1,THNSL2,EYA1,INPP5J,INPPL1,IMPA2,NTPCR,MTMR4,BTRC,PTEN,ITPK1,INPP5D,PTPN21,PP2D1,PTPRK,INPP1,PTPRN,PSPH,DUSP27,PPTC7,PPP5C,PPP1R3B,CAMK2G,PFKFB4,PPP3R1,RPRD1A,PDP1,DUSP19,DUSP21,PTPRG,PPP1R12A,PTPN7,PPM1N,PDPR,CDC25C,DLGAP5,DUSP3,SSH1,SGPP1,PPP1CB,THTPA,PPP1R3E,DUSP7,PPEF1,EPM2A,INPP5A,MTMR14,DUSP28,CTDSP2,PPM1M,SACM1L,DUSP4,INPP5F,RPRD1B,MYH8,DUSP26
GO:0007589	body fluid secretion	GO_BODY_FLUID_SECRETION	0.260212105334127	1.06275399428929	0.344558260900227	0.752617200642547	65	ATP7A,STAT5B,VIP,PPAT,CCND1,VAMP2,CEL,UCN,SLC4A5,COPA,ERBB4,CREB1,NCOR1,VEGFA,USF2,NCOA1,AGR2,CAD,DHODH,CSN2,CSN3,MED1,XDH,SLC22A2,UMPS
GO:0043044	atp dependent chromatin remodeling	GO_ATP_DEPENDENT_CHROMATIN_REMODELING	0.263917805936099	1.06354843635309	0.34484164259256	0.752747710095043	61	SMARCB1,NASP,CENPK,NPM1,HDAC2,CENPA,CHD8,HIST1H4F,PSME4,HIST1H2BA
GO:0042255	ribosome assembly	GO_RIBOSOME_ASSEMBLY	0.282631705556672	1.06901982383008	0.345451601878002	0.753169624582952	45	DDX3X,ERAL1,NPM1,C1QBP,RPL3L,MDN1,SBDS,MRTO4,FASTKD2,ABT1,MRPL20,DHX30,RPS14
GO:0071705	nitrogen compound transport	GO_NITROGEN_COMPOUND_TRANSPORT	-0.183405686900028	-1.02660267402395	0.345482442173523	0.753169624582952	464	SCN4A,SLC1A6,PDPN,P2RX1,SLC36A2,SMPD3,SLC28A3,SNAP25,UBE2Q1,NXF5,AQP1,AGFG1,ILDR2,AQP3,SLC22A4,AMN,SLC1A1,SLBP,SLC7A3,DDX19A,SLC17A5,SNCA,ANXA1,SLC6A17,SLC38A2,SLC18A1,SLC22A3,SLC25A6,SLC7A10,DDC,SLC17A7,SLC7A8,STXBP3,SLC7A2,SLC29A4,SLC6A3,HNRNPA3,SNAP23,THOC6,PCLO,EIF2AK3,SLC35A3,PRAF2,LEP,SLC19A3,SLC35F3,IGF2BP2,SEC13,SLC18A2,CALHM1,FLVCR2,SMAD2,SLC25A22,SLC48A1,SLC1A4,NUP50,FOLR3,UNC13B,ABCA1,SERINC2,SLC25A19,ARL6IP5,RHCE,SLC38A1,GPR119,PICK1,DDX25,SLC30A8,FYTTD1,SLC38A8,MVP,STXBP1,SLC44A5,AQP11,ADCYAP1,FIP1L1,CACNB4,SLC6A14,GAL,ACVR2B,RPS28,CARTPT,DDX39A,SLC7A4,SIDT1,CLN3,SLC32A1,CYB5R4,OAZ3,EDN1,FCER1A,SLC7A9,SLC3A2,SLC23A2,RBMX2,SLC17A6,SLC44A1,SLC38A11,LUZP4,GRM2,THOC7,SLC6A9,AQP9,LMBRD1,PSEN1,SLC16A2,SLC18A3
GO:0032292	peripheral nervous system axon ensheathment	GO_PERIPHERAL_NERVOUS_SYSTEM_AXON_ENSHEATHMENT	0.343508526849763	1.08115367171104	0.346141778786704	0.753708445746273	21	LAMA2,AKT2,SH3TC2,SOD1,DICER1
GO:0031998	regulation of fatty acid beta oxidation	GO_REGULATION_OF_FATTY_ACID_BETA_OXIDATION	0.378477546723306	1.08754292084372	0.346177438242347	0.753708445746273	15	AKT2,PPARA,LONP2,IRS1,MTOR,ACACB,TWIST1
NA	positive regulation of protein complex disassembly	GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY	0.334368919014585	1.07808853999879	0.347176812020132	0.754804777780204	23	FAM21C,SETX,TNF,SEMA5A,CFL2,NES,ACTN2,SYNJ1,BNIP3
GO:0048008	platelet derived growth factor receptor signaling pathway	GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	0.306136571096525	1.07176903022221	0.347198193440294	0.754804777780204	32	RAPGEF1,NRP1,PDGFB,JAK2,PTEN,RGS14,VEGFA,GAB1
GO:0017156	calcium ion regulated exocytosis	GO_CALCIUM_ION_REGULATED_EXOCYTOSIS	-0.243572993845877	-1.05389381506	0.347366228476208	0.754804777780204	73	STX19,SYT4,SNAP25,NLGN1,SYTL1,SYT17,TRIM9,RPH3A,C2CD4D,SNAP23,PCLO,STX11,SYT6,CDK5,UNC13B,SCIN,SYT5,STX2
GO:0042472	inner ear morphogenesis	GO_INNER_EAR_MORPHOGENESIS	-0.235225648746991	-1.0508655146381	0.347981220657277	0.754804777780204	87	PAX8,PDZD7,WNT5A,MYO15A,ATP6V1B1,NEUROG1,GATA3,PTK7,FGFR2,GBX2,OTX1,ATP2B2,USH1G,NR4A3,HMX3,FZD3,FGF9,DLX6,KCNQ4
GO:0010869	regulation of receptor biosynthetic process	GO_REGULATION_OF_RECEPTOR_BIOSYNTHETIC_PROCESS	-0.335972767134908	-1.07362200966737	0.348244201731865	0.754804777780204	20	CNPY2,HIF1A,SCAP,ADIPOQ,SEC24A,PPARG,NR1H3
GO:0072511	divalent inorganic cation transport	GO_DIVALENT_INORGANIC_CATION_TRANSPORT	-0.197641523612709	-1.03475174159336	0.348276850139363	0.754804777780204	247	SLC24A3,TRPM3,BBC3,CCL3,CACNG4,CCL19,TRPV5,TRPV3,SLC39A8,GPM6A,RYR1,PKD1L3,CTGF,STIM2,ANO6,ANXA5,OPRM1,TMEM37,SLC39A6,SLC39A2,ATP2B2,PKDREJ,SLC30A2,GRIN2A,CCL21,CACHD1,CACNG3,SLC39A10,CACNA1F,SLC25A25,CACNB1,TPT1,ATP2B3,CHRNB2,CALHM1,CDK5,CACNA1I,ORAI1,TRPM6,NIPAL4,RYR3,ITPR3,TMC2,SLC30A8,KCNN4,SLC30A9,SLC8A3,NIPAL2,CACNG2,GRIN3B,ASPH,CACNB4,F2R,RASA3,CASK,PKD2,SLC39A1,BHLHA15,CACNA1S
GO:0035794	positive regulation of mitochondrial membrane permeability	GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY	0.370978721992174	1.08397572107037	0.348573552643806	0.754804777780204	16	RHOT2,BAD,MOAP1,ATF2,BID,BMF,BNIP3
GO:0002088	lens development in camera type eye	GO_LENS_DEVELOPMENT_IN_CAMERA_TYPE_EYE	-0.251094383305689	-1.05511722528918	0.34901411040125	0.754804777780204	63	CDON,TGFBR1,BMP4,WNT5A,WNT2B,GATA3,SOX11,SKIL,CTNNB1,WNT7B,BCAR3,EPHA2,SHROOM2,PITX3,PYGO2,DLG1
NA	positive regulation of nf kappab import into nucleus	GO_POSITIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS	-0.30863223524002	-1.06851335306625	0.349324874997247	0.754804777780204	27	CCL19,IL18,TNFSF14,EDAR,NLRP12,TLR9,RHOA,TLR2
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION	0.22213079484893	1.04628158319568	0.34932689567302	0.754804777780204	153	CDKL5,NRP1,IL1RAPL1,UNC13D,C1QBP,HDAC2,LPAR3,PAFAH1B1,TIAM1,RAB21,TRPV2,MEGF8,BCL9L,ZEB2,MACF1,GSK3B,OBSL1,TGFBR2,GOLGA4,GLIPR2,LIMK1,EZH2,EP300,FBXO31,GCNT2,SEMA5A,CAMK2B,VEGFA,EPHA4,L1CAM,SMAD3,BHLHB9,LIMS1,BCL11A,BAMBI,MARCKS,NTRK3,TGFB3,ITPKA,PLXNB3
GO:0010907	positive regulation of glucose metabolic process	GO_POSITIVE_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS	0.305669996932327	1.07013557709475	0.349328914060935	0.754804777780204	32	AKT2,PPARA,IRS1,GCK,KAT2A,FOXO1,HMGB1,PTH,PHKG2,GCG,EPM2AIP1,SORBS1,PPARGC1A,GPLD1,INSR,ARPP19
GO:0021522	spinal cord motor neuron differentiation	GO_SPINAL_CORD_MOTOR_NEURON_DIFFERENTIATION	-0.289971556078987	-1.062859296717	0.349598010038644	0.754804777780204	34	LHX4,NKX6-1,GBX1,GDPD5,HOXC10,OLIG3,MDGA2,ISL2
GO:0060324	face development	GO_FACE_DEVELOPMENT	-0.272520218859172	-1.06086589545895	0.350068574768982	0.754804777780204	44	SOX3,RARA,WNT5A,GRHL2,MAP2K2,SGPL1,PAX9
GO:0051125	regulation of actin nucleation	GO_REGULATION_OF_ACTIN_NUCLEATION	-0.314730426360162	-1.0676048800825	0.350574586363736	0.754804777780204	25	WASF1,WHAMM,SCIN,PICK1,WIPF2,TRIM27,CORO1B,NCKAP1
GO:0006448	regulation of translational elongation	GO_REGULATION_OF_TRANSLATIONAL_ELONGATION	0.337568937397775	1.07523280874326	0.351052273020198	0.754804777780204	22	CPEB3,CPEB2,LARS2,IARS2,IMP3,YRDC,PRORSD1P
GO:1902749	regulation of cell cycle g2 m phase transition	GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.267705587324013	1.06032865110258	0.351328222499554	0.754804777780204	56	FOXN3,NPM1,APP,CCND1,TAOK3,PKIA,SMARCD3,CDK5RAP3,CDK1,HUS1,CLSPN,FOXO4,MRE11A,RINT1,PRKCQ,PHOX2B,SIN3A,PLK1,CDKN2A,ATM,RNASEH2B,NEK10,FHL1,VPS4B,HSPA2,CAMK2D,USP47
GO:0043551	regulation of phosphatidylinositol 3 kinase activity	GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_ACTIVITY	0.290701888602328	1.06521510654383	0.351413389242337	0.754804777780204	39	PIK3R1,PDGFB,ATG14,FLT1,PIK3R3,IRS1,ERBB4,TEK,PIK3R5,PIK3IP1
GO:0035162	embryonic hemopoiesis	GO_EMBRYONIC_HEMOPOIESIS	-0.345435166475082	-1.07273297319286	0.351435691840936	0.754804777780204	18	KDR,GATA3,HIF1A,STK3
GO:0009994	oocyte differentiation	GO_OOCYTE_DIFFERENTIATION	-0.287446405692907	-1.06132798576367	0.351484708392603	0.754804777780204	35	DMRT1,INSL3,REC8,CTNNB1,YBX2,CCNB1,KIAA0196,FBXO5,NPM2,AURKC,FOXO3,PABPC1L,FOXL2,BCL2,RPS6KA2,PTK2B
GO:0042596	fear response	GO_FEAR_RESPONSE	0.322819719675608	1.07344462655306	0.351656612699169	0.754804777780204	26	USP46,ADRB1,DRD4,ALS2,FBXL20,ESR2,VDAC1
GO:0021543	pallium development	GO_PALLIUM_DEVELOPMENT	-0.213414391054381	-1.04064052887995	0.351697945695332	0.754804777780204	148	CCDC85C,PHLPP2,DLX1,ANXA3,RARA,CDON,ID4,GART,RTN4,SEMA3A,FUT10,LHX5,SLC38A2,POU3F2,POU3F3,CTNNB1,GNG12,NR4A3,UBA6,EGFR,HIF1A,LRP8,EMX1,CASP3,CDK5,HTR5A,FGF13,LMX1A
GO:2000177	regulation of neural precursor cell proliferation	GO_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION	0.255539807431489	1.05569911364484	0.351746490285533	0.754804777780204	69	ELL3,RAPGEF1,KDM2B,LRRK2,GLI2,DRD2,CDH2,CTNNA1,SMARCD3,LIMS2,SHH,CX3CL1,SHCBP1,DLL4,FOXO1,CCR2,VEGFA,PAX6,LHX1,EGF,PROX1,GATA2,ASCL1,NES,SMO,SIRT2,GNG5
GO:0008156	negative regulation of dna replication	GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION	0.273184040652623	1.06174688459211	0.351838590712163	0.754804777780204	51	FBXW7,MCRS1,OBFC1,FBXO18,ZRANB3,GTPBP4,SMC1A,LIG3,ACD,HUS1,MRE11A,TGFB3,TIPIN,BRCA2
GO:0021904	dorsal ventral neural tube patterning	GO_DORSAL_VENTRAL_NEURAL_TUBE_PATTERNING	-0.358040112871843	-1.07582044265767	0.352209017901595	0.755118187424694	16	PAX7,BMP4,FOXA1,WDR19
GO:0071346	cellular response to interferon gamma	GO_CELLULAR_RESPONSE_TO_INTERFERON_GAMMA	0.233767579483636	1.04912462022666	0.35275501650786	0.755478566580242	111	CCL1,IRF2,CAMK2A,IRF6,XCL1,TRIM26,CCL24,SP100,OAS2,JAK2,CIITA,HLA-B,CX3CL1,CAMK2G,OASL,HLA-H,OAS3,IRF1,OAS1,GBP5,DAPK3,GBP1,CAMK2B,CCL16,GBP2,TRIM31,PTAFR,NCAM1,CCL23
GO:1903827	regulation of cellular protein localization	GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION	0.191584707001442	1.03137002652346	0.353009013383509	0.755478566580242	498	SPAG5,PRKACA,PARL,BAD,PIK3R1,RBCK1,GPM6B,FLCN,AKT2,FBXW7,PYDC2,GPHA2,NRXN1,TP53INP2,DYNLL2,ATPIF1,HNRNPM,VPS4A,EDEM2,LRRK2,GZMB,AKAP1,RANGAP1,PIN1,ITGAX,SH3TC2,KIF5B,RNF31,MCRS1,KAT7,NEDD4L,VAMP2,CDH2,C8orf4,SP100,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,SUFU,PKIA,GSK3B,AKAP6,JAK2,CAV3,DDX58,CDK5RAP3,SIAH3,CSF3,HUWE1,SIRT4,CYB5R1,CABP1,RGS20,IFI27,MBTPS1,PSMB7,AGTR2,KAT2A,UBR5,PDE2A,DERL3,NMT1,SHH,AR,SAE1,XPO4,NUCB1,EP300,TCP1,STX4,ERBB4,RAMP3,PPP3R1,PPP1R13B,MTOR,IL18R1,GBP1,YOD1,TNF,SEMA5A,TMEM173,EMD,ARIH2,PARK7,PPFIA1,CDK1,VEGFA,PSMD8,BAG4,AP2M1,APC,USP36,FAF1,ANK3,CCT3,ZMYND8,RDX,KANK1,MDFI,HYAL2,AGR2,CD36,SMAD3,GBF1,OAZ1,TPR,BID,KCNN3,BAMBI,BCAS3,LITAF,MAPK8,RANBP3,NFKBIA,TREM2,ARF6,COMMD1,EGF,TLR4,TGFB3,FAM89B,MED1,YWHAG,CCT7,WRAP53,CCT4,EDA,PRKCQ,WBP11,JUP,TP53BP2
GO:0072210	metanephric nephron development	GO_METANEPHRIC_NEPHRON_DEVELOPMENT	-0.293857622445134	-1.06119164529766	0.353995254041827	0.755478566580242	32	PAX8,OSR1,WT1,BMP4,IRX1,GDNF,CD34,PKD2,IRX2
GO:1904036	negative regulation of epithelial cell apoptotic process	GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS	-0.289041675709513	-1.05945092105114	0.354150935015324	0.755478566580242	34	SCG2,KDR,ANGPT1,GATA3,ANGPTL4,NFE2L2,ABL1,IL10,KRIT1,GAS6,NEUROD1,SERPINB13,IGF1
GO:0002228	natural killer cell mediated immunity	GO_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY	0.325387866831819	1.07127535632015	0.354407149804555	0.755478566580242	25	UNC13D,GZMB,KIR3DL1,KLRF2,VAMP2,ULBP1,MICA
GO:0035306	positive regulation of dephosphorylation	GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION	0.283395104032657	1.06160953455182	0.354579018460153	0.755478566580242	43	DLC1,PPP1R16B,CALM3,PIN1,PINK1,AKAP6,JAK2,CD300A,AGTR2,CALM1,SYMPK,PPP1R12A,SMAD3,DUSP26,MEF2C,SMPD1,GPLD1,SPPL3,PPP1R15A,PPP1R7
GO:0070303	negative regulation of stress activated protein kinase signaling cascade	GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE	-0.277950678226919	-1.05842961201005	0.35458006718925	0.755478566580242	40	EZR,MAPK8IP1,FOXM1,SFRP2,MEN1,TP73,HDAC3,FKTN,ZNF675
GO:0071392	cellular response to estradiol stimulus	GO_CELLULAR_RESPONSE_TO_ESTRADIOL_STIMULUS	-0.302088901653534	-1.06448843641237	0.354638947252018	0.755478566580242	29	SSTR3,SSTR2,EGFR,MSX2,CCNA2,MYOD1,ZNF703,PAWR,IL10,NRIP1,CCDC62
GO:0014037	schwann cell differentiation	GO_SCHWANN_CELL_DIFFERENTIATION	0.310139038194556	1.06888754764856	0.354887547197344	0.755478566580242	30	LAMA2,AKT2,SH3TC2,LAMB2,MED12,SOD1,DICER1,GPC1
GO:0006767	water soluble vitamin metabolic process	GO_WATER_SOLUBLE_VITAMIN_METABOLIC_PROCESS	-0.238232273920905	-1.04843755008458	0.354901092756122	0.755478566580242	80	PTGIS,SHMT1,AOX1,ALDH1L1,AMN,MTHFD1L,PC,PDZD11,BTD,SLC19A3,PSAT1,MMADHC,HLCS,DHFR,NAMPT,FASN,ALDH1L2,CYB5A,SLC2A1,ACPP,SLC23A2
GO:0002576	platelet degranulation	GO_PLATELET_DEGRANULATION	0.239319169506253	1.0498619310061	0.354941900677825	0.755478566580242	97	ITIH3,PHACTR2,VWF,PDGFB,SERPINF2,HABP4,APP,CALM3,ITGB3,F8,VEGFB,CYB5R1,TTN,CALM1,ITGA2B,SELP,VEGFA,TIMP3,ALDOA,SOD1,SPP2
GO:0046685	response to arsenic containing substance	GO_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE	0.321938099776575	1.07051305178982	0.355488732833385	0.755478566580242	26	DDX3X,CPEB2,PPIF,ABCC2,PTEN,ALAD,SRRT,CYP1A1,FECH,GSTO1,NEFL,RNF4
GO:0048477	oogenesis	GO_OOGENESIS	-0.25280501970337	-1.05221972679844	0.355744603000366	0.755478566580242	60	DMRT1,INSL3,REC8,CTNNB1,BMPR1B,YBX2,PAQR5,CCNB1,KIAA0196,FBXO5,TAF4B,FMN2,NPM2,AURKC,GPR149,FOXO3,PABPC1L,RPS6,FOXL2,BCL2,RPS6KA2
GO:0034260	negative regulation of gtpase activity	GO_NEGATIVE_REGULATION_OF_GTPASE_ACTIVITY	0.293661445631785	1.06365966071207	0.355884642540326	0.755478566580242	37	AMOT,LRRK2,CPEB2,FZD10,CDC42SE1,ARFGEF1,RHOH,RDX,MKKS,BCAS3,PLXNB3
NA	single organism membrane fusion	GO_SINGLE_ORGANISM_MEMBRANE_FUSION	0.233386979815482	1.04741652844082	0.355971055647741	0.755478566580242	111	C2CD4A,DYSF,SYT9,VCPIP1,TIE1,MFN2,USP30,SYT8,VPS4A,SYTL2,VAMP2,MFN1,STX1A,SYT7,VPS11,VTI1A,VPS39,STX4,SEC22C,SYT12,SYTL3,PLD6,VAMP1,RPH3AL,GOSR1,TMEM8C,TMEM175,C2CD4B,OPA1,UVRAG,BAK1,STX10,DOC2B,LRMP,SYTL4
GO:0050867	positive regulation of cell activation	GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION	-0.193206454767955	-1.02918289399459	0.356146515466113	0.755478566580242	286	CD55,TCF3,DPP4,TNFSF11,CCL19,EFNB3,RARA,IL18,WNT5A,CTGF,TNFSF14,GATA3,HLA-DRB5,ANXA1,TACR1,CLCF1,MAP3K8,XBP1,BST1,IL6ST,PYCARD,CCL21,NR4A3,RIPK2,CDKN1A,SLC39A10,IL36B,IGHG4,LEP,TNFSF9,CHRNB2,LILRB2,IGHG2,VAMP8,IGHG1,WHSC1,RAG1,ZBTB1,PAK3,ATP11C,IGHD,NLRP3,IL5,SART1,RPS6KA1,BTLA,SOX15,THBS1,GRAP2,IGKC,PDPK1,NKAP,IL2RA,IGLL1,MIF,IGLC1,VTCN1,CDC42,FCER1A,HLA-DRB1,GPAM
GO:0006353	dna templated transcription termination	GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION	-0.230825913881648	-1.04509091004885	0.356210386907577	0.755478566580242	94	POLR2H,ZNF473,SNRPF,SLBP,TAF1D,XRN2,PRMT5,TBP,POLR2K,CD3EAP,THOC6,GTF2H2,POLR1B,SNRPE,UBTF,GTF2H1,PAPOLA,FIP1L1,SNRPB,DDX39A
GO:0031365	n terminal protein amino acid modification	GO_N_TERMINAL_PROTEIN_AMINO_ACID_MODIFICATION	0.340718142951451	1.07237125857909	0.356753963420261	0.755478566580242	21	NAA30,CREBBP,NAA25,NMT1,EP300,NAA50,METAP1,NAA11,METAP2,PPM1B
GO:0044774	mitotic dna integrity checkpoint	GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT	0.241046884233841	1.04961654110857	0.356782263240983	0.755478566580242	93	PPP2R5C,FOXN3,NPM1,CCND1,TAOK3,PLAGL1,CDK5RAP3,TFDP2,CNOT6L,CNOT4,DGKZ,EP300,FBXO31,CDKN1B,CDK1,ATF2,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,CLSPN,GIGYF2,FOXO4,PRKDC,MRE11A,CNOT1,TIPIN,TOP2B,CASP2,RBL2,MDM4
GO:0043101	purine containing compound salvage	GO_PURINE_CONTAINING_COMPOUND_SALVAGE	0.375209559603541	1.07815246614362	0.357032658599602	0.755478566580242	15	CECR1,GMPR,ADA
GO:0072010	glomerular epithelium development	GO_GLOMERULAR_EPITHELIUM_DEVELOPMENT	-0.349829644729456	-1.06988548136103	0.35713976727084	0.755478566580242	17	WT1,BMP4,NPHS1,MAGI2,CD34,BASP1,PODXL
GO:0030901	midbrain development	GO_MIDBRAIN_DEVELOPMENT	-0.234931579470285	-1.04544708707602	0.35731487759826	0.755478566580242	85	CMA1,WNT5A,SFRP2,POTEE,LDHA,RFX4,FGFR2,OTX2,OTX1,CTNNB1,DLG5,YWHAH,FZD3,MAG,FGF9,CCDC14,LMX1A,DYNLL1,RHOA,PITX3,BASP1,CDC42
GO:0043300	regulation of leukocyte degranulation	GO_REGULATION_OF_LEUKOCYTE_DEGRANULATION	0.287671244729822	1.05995641105987	0.358541696776991	0.755680959915687	40	UNC13D,VAMP2,CEACAM1,ABR,CD300A,STX4,CCR2,IL4,ADORA2B,PTAFR
GO:0045785	positive regulation of cell adhesion	GO_POSITIVE_REGULATION_OF_CELL_ADHESION	-0.188594998479075	-1.02687439292004	0.359193579525083	0.755680959915687	351	VTN,PRKCA,CD55,DPP4,CCL28,ITGA3,TNFSF11,CCDC80,CCL19,EFNB3,KDR,RARA,IL18,WNT5A,S100A10,SFRP2,TNFSF14,NPNT,ANGPT1,GATA3,ALOX15,HLA-DRB5,FOXF1,FOXA1,NPY2R,ITGB1BP1,CYR61,DMP1,CALR,ANXA1,MAP3K8,SPOCK2,XBP1,IL6ST,PYCARD,CCL21,NR4A3,RIPK2,CSF1,IL36B,PIEZO1,ABI3BP,RHOD,SAA1,TFE3,TRIOBP,LEP,TNFSF9,LILRB2
GO:0046209	nitric oxide metabolic process	GO_NITRIC_OXIDE_METABOLIC_PROCESS	-0.363571507731532	-1.07106974751053	0.359738545116118	0.755680959915687	15	SLC7A2,CPS1,NQO1,DDAH2
GO:2000648	positive regulation of stem cell proliferation	GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION	-0.252228705759304	-1.0498210050425	0.359860958653494	0.755680959915687	60	DPPA2,KDM1A,BMP4,WNT5A,FGFR2,FOXF1,SOX11,CTNNB1,HIF1A,FZD3,FGF9,SIRT6
GO:0071377	cellular response to glucagon stimulus	GO_CELLULAR_RESPONSE_TO_GLUCAGON_STIMULUS	0.299305518493059	1.062545759102	0.360229918509895	0.755680959915687	34	GNAS,PRKACA,GNG2,GLP1R,ADCY7,PRKAR1A,ADCY5,GNB3,GNG11,ADCY8,ADCY9,ADCY4
GO:0060759	regulation of response to cytokine stimulus	GO_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS	-0.217321514683726	-1.03695709088855	0.360295912886371	0.755680959915687	129	WNT5A,PTPN2,ANGPT1,SOCS1,KLF4,IRAK1,SLIT3,IL6ST,PYCARD,RIPK2,RIPK1,CSF1,PELI3,IFNA14,CHUK,HIF1A,TRADD,UBA52,IRF7,TNFRSF1A,ADIPOQ,IRAK3,IKBKG,PPARG,NR1H3,IFNA16,ZNF675,IFNAR1
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	GO_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS	0.271777954848395	1.05628204404527	0.360449711769129	0.755680959915687	51	LRP5,BAD,TRPM4,NRXN1,TIAM1,CDK16,HMGCR,ADCY5,ANO1,STX4
GO:0007270	neuron neuron synaptic transmission	GO_NEURON_NEURON_SYNAPTIC_TRANSMISSION	-0.256009254545574	-1.04961467506999	0.360562033157224	0.755680959915687	56	P2RX1,DRD5,SNCA,DLGAP2,SLC17A7,SLC6A3,CLSTN3,GLRA4,CDK5,SLC1A4,GRID2,UNC13B,CDH8,GRIK2,CACNB4,SHC3,SLC6A9,GABRG2,GABRB2,CNIH2,RAC1
GO:0031498	chromatin disassembly	GO_CHROMATIN_DISASSEMBLY	0.361309540235421	1.07334646616131	0.360679214402619	0.755680959915687	17	SMARCB1,HMGA1,SMARCD3,HIST1H2BA
GO:0045833	negative regulation of lipid metabolic process	GO_NEGATIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS	-0.249399214780601	-1.04799400139607	0.361400928436825	0.755680959915687	63	APOA2,CNR1,APOC1,ACADL,ORMDL2,BMP2,CIDEA,AKR1C3,DGAT2,HCAR2,SCAP,BMP5,PPP2R5A
GO:0008207	c21 steroid hormone metabolic process	GO_C21_STEROID_HORMONE_METABOLIC_PROCESS	-0.312396142192505	-1.05968669690043	0.361429105051526	0.755680959915687	25	CYP11A1,FDX1L,FDXR,AKR1C3,STAR,STARD5,AFP,FSHB
GO:0009132	nucleoside diphosphate metabolic process	GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS	0.249950501053186	1.04820199024441	0.361773184278985	0.755680959915687	75	BAD,CMPK2,DLG4,OGDHL,ENTPD4,AK1,PGAM2,PGAM1,OGDH,DLG2,DHTKD1,AK4,PFKM,GCK,PFKFB4,NME6,PFKP,ALDOC,ALDOA,HK3,ENO2,GALK1,NME5
GO:0032656	regulation of interleukin 13 production	GO_REGULATION_OF_INTERLEUKIN_13_PRODUCTION	-0.348569478184188	-1.06603150868836	0.361833282865424	0.755680959915687	17	RARA,TNFRSF21,GATA3,IRF4,NLRP3,IL17RB
GO:0043038	amino acid activation	GO_AMINO_ACID_ACTIVATION	0.27540366816468	1.05612520917502	0.362183060600611	0.755680959915687	48	TARS2,PARS2,EARS2,LRRC47,LARS2,MARS,IARS2,AIMP2,WARS,MRPL39,MARS2,QRSL1,TARS,SARS2
GO:0006998	nuclear envelope organization	GO_NUCLEAR_ENVELOPE_ORGANIZATION	0.252174189326848	1.04967363524142	0.362525745066629	0.755680959915687	72	LPIN1,POM121,SUN1,PAFAH1B1,DMPK,NUP85,RAE1,CHMP7,SUN5,NUP188,NEK9,EMD,CDK1,BANF1,LEMD2,SYNE2,SUMO1,TPR,AAAS,PARP11,POM121C,UBXN2B,AKAP8L,CTDNEP1,NUP214,CHMP4B,PLK1,NUP35
GO:1904951	positive regulation of establishment of protein localization	GO_POSITIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION	-0.182447753072332	-1.02199358504905	0.362926095260142	0.755680959915687	467	ATP13A2,CFTR,GPR26,BBC3,RBP4,SFN,EZR,CCL3,GSDMD,DPCR1,ITGA3,CCL19,NKX6-1,ARHGEF5,IL18,TGFBR1,BMP4,WNT5A,SFRP2,TNFSF14,GATA3,PEMT,PRKCI,HLA-DRB5,TDRD12,ITGB1BP1,IPO5,XBP1,UBL4B,EDAR,WDR75,TP73,SULF2,WDR46,PYCARD,ARHGEF16,BCAP31,SH3GLB1,YWHAH,HDAC3,EGFR,LPL,SERP1,HIF1A,UBE2L3,SAA1,HCAR2,LEP,DAB2,SEC24A,IL17RC,ANXA13,CDK5,NNAT,SORL1,CDKL2,CLEC5A,RAPGEF3,IL17F,CTSK,ZDHHC8,CDH1,KCNB1,C5,PCM1,CLEC4E,SLC30A8,NLRP3,IL5,NLRP12,TLR9,CD34,KCNN4,RHOG,DYNLL1,STXBP5L,HNMT,IFNAR1,CTDSPL2,ASPH,EPHA2,ADAM9,PDPK1,NKAP,F2R,HSP90AA1,LRP1,MFF,RHOA,ABAT,TLR2,NODAL,MDM2,MIF,RNASE2,VTCN1,CDC42,HLA-DRB1,IL17RB,MAPK11,PTGER4,DLG1,UBE2J2,WNK3,CCT5,YWHAB,ABL1,ZBTB17
NA	positive regulation of protein complex assembly	GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY	0.215844376502616	1.03737423589694	0.363166896368497	0.755680959915687	177	CUL4A,TUBGCP5,CLASP1,PSMC6,CLIP1,TUBGCP2,TAF1,CCL24,PINK1,FNIP1,GSK3B,CAV3,SPIRE1,CSF3,ACTR3B,FAM21C,MED25,PSMC5,ERCC1,GTF2H3,ERCC4,SETX,MTOR,GBP5,CREB1,TNF,NKX2-5,CSF2,CDKN1B,HDAC6,VEGFA,BAG4,VCP,JMY,GTF2H5,FAF1,TUBGCP6,C15orf62,MITF,CD36,FNIP2,MLST8,SUMO1,BID,PRKCE,TUBGCP3,PFN2,ARF6,GTF2F2,TLR4,CAPG,FOSL1,SRF,TWIST1,PAXIP1,TMEM27,IRF8,SPIRE2,HRK,BMF,GRB2
GO:0097529	myeloid leukocyte migration	GO_MYELOID_LEUKOCYTE_MIGRATION	-0.233353881464983	-1.04250343465844	0.36349765258216	0.755680959915687	87	SCG2,CCL3,TNFSF11,CCL19,ARHGEF5,IRAK4,RPS19,ANXA1,UMOD,S100A12,CCL21,SAA1,IL17RC,C5AR1,S100A9,EDNRB
GO:0044241	lipid digestion	GO_LIPID_DIGESTION	0.334536760013668	1.06557464342019	0.363517519471194	0.755680959915687	22	CLPS,LIPN,LDLR,CEL,LIPG
GO:0021766	hippocampus development	GO_HIPPOCAMPUS_DEVELOPMENT	-0.242301765738571	-1.04555352849388	0.363537446463711	0.755680959915687	72	PHLPP2,DLX1,ANXA3,RARA,ID4,LHX5,NR4A3,UBA6,LRP8,CASP3,CDK5,HTR5A,FGF13,LMX1A,KCNA1
GO:0032693	negative regulation of interleukin 10 production	GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION	0.366727029764567	1.07155255263785	0.363553573088003	0.755680959915687	16	TRIB2,IDO1,PRG2,LILRB1,JAK3,FOXP3,CD274,PDCD1LG2,TNFRSF9,EPX,DLL1,AGER,IL12B
GO:0070374	positive regulation of erk1 and erk2 cascade	GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE	-0.210696638940013	-1.03515308643979	0.363557580409538	0.755680959915687	156	PLA2G2A,CHI3L1,PRKCA,C3,CCL3,TNFSF11,CCL19,KDR,BMP4,BMP2,CTGF,NPNT,ANGPT1,FSHR,ALOX15,FGFR2,OPRM1,FGF18,PYCARD,CCL21,RIPK2,EGFR,FGF4,ABCA7,TNFAIP8L3,C5AR1
GO:0060043	regulation of cardiac muscle cell proliferation	GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION	0.310577731003938	1.06147325464392	0.363681165239929	0.755680959915687	29	TBX2,BMP10,GJA1,TGFBR2,FGFR1,ERBB4,TBX5,TBX20,NKX2-5,CDK1,HEY2
GO:0030838	positive regulation of actin filament polymerization	GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION	-0.249841202341825	-1.04673479340985	0.363801133365453	0.755680959915687	62	BAIAP2L2,ALOX15,ARPC5,EVL,ACTR3,KIRREL,NPHS1,PYCARD,CCL21,BAIAP2,CDC42EP1,SCIN
GO:0035418	protein localization to synapse	GO_PROTEIN_LOCALIZATION_TO_SYNAPSE	0.373113882157507	1.0721306051626	0.363817171322887	0.755680959915687	15	NRXN1,DLG4,SHANK1,DLG2
GO:0045684	positive regulation of epidermis development	GO_POSITIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT	-0.30002155390609	-1.05720360152054	0.364104832467102	0.755680959915687	29	SFN,BMP4,WNT10B,HPSE,TMEM79,MSX2,TRADD,IL20
GO:0002707	negative regulation of lymphocyte mediated immunity	GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.29851589969798	1.05974258291519	0.364195285215367	0.755680959915687	34	XCL1,SPN,CEACAM1,HLA-B,CR1,MICA,LILRB1,BCL6,FOXJ1,HLA-E,TAP1,SUSD4,FOXP3,PPP3CB
GO:0046887	positive regulation of hormone secretion	GO_POSITIVE_REGULATION_OF_HORMONE_SECRETION	-0.221861978760988	-1.03851416034565	0.364207939872808	0.755680959915687	114	CFTR,NMU,RBP4,TNFSF11,NKX6-1,NMB,RETN,HLA-DRB5,C1QTNF1,SOX11,TACR1,SERP1,HIF1A,HCAR2,LEP,VAMP8,NNAT,SLC30A8,ADCYAP1,GAL,CARTPT,ABAT,TMF1,EDN1,HLA-DRB1,PTGER4,INHBA
GO:0006706	steroid catabolic process	GO_STEROID_CATABOLIC_PROCESS	-0.319617639106183	-1.06011533965319	0.364244951712028	0.755680959915687	23	HSD17B6,YWHAH,CYP1A2,HSD17B14,CYP7A1,TRERF1,SULT2A1,STS,APOE,CYP46A1,FGF23,CYP39A1
GO:0050807	regulation of synapse organization	GO_REGULATION_OF_SYNAPSE_ORGANIZATION	-0.226363727749029	-1.03915967689322	0.364297638922013	0.755680959915687	102	LRRN1,SLITRK2,IGSF9,NLGN1,AGRN,FLRT3,WNT5A,SLITRK4,LRRC4B,EFNA5,CBLN2,TPBG,FLRT2,SRPX2,FLRT1,CLSTN3,ROBO2,CHRNB2,MAGI2,AMIGO2,CDC20,ARHGEF15,THBS2,RAB17,CDC42,SLITRK5,PDLIM5
GO:0048873	homeostasis of number of cells within a tissue	GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS_WITHIN_A_TISSUE	-0.299957785216914	-1.05697889603861	0.364370231117992	0.755680959915687	29	CD7,ILDR2,KRAS,CSF1,PRDM14,BAX,F2R,IL20RB,BCL2,RAC1,KLHL10
GO:0035050	embryonic heart tube development	GO_EMBRYONIC_HEART_TUBE_DEVELOPMENT	0.253166047996392	1.04834668636738	0.364772887572295	0.755863665283122	70	TBX2,NDRG4,C2CD3,MEGF8,RYR2,HAND2,YAP1,IFT172,GJA1,SUFU,SHH,GJA5,TBX20,NKX2-5,SOX17,ENG,SETDB2,MKKS,SMAD3,FGF8,TBX3,MED1,NOTO,MEF2C,SRF
GO:0072384	organelle transport along microtubule	GO_ORGANELLE_TRANSPORT_ALONG_MICROTUBULE	0.271175435267784	1.05394031395704	0.364907443875542	0.755863665283122	51	RHOT2,NDE1,FYCO1,KIF13A,PAFAH1B1,RAB6A,KIF5B,PEX14,PRKCZ,TMEM201,ARHGAP21,MAP1S,AP3M2,HTT
GO:0043966	histone h3 acetylation	GO_HISTONE_H3_ACETYLATION	0.28630644067478	1.05492764007742	0.365461049284579	0.756037562874227	40	TRIM16,MEAF6,KAT7,DR1,KAT6A,KAT2A,EP300,BRD1,LDB1,SPI1,CRTC2,KAT6B,SUPT7L,ING5,BRCA2,PER1
GO:1903335	regulation of vacuolar transport	GO_REGULATION_OF_VACUOLAR_TRANSPORT	0.310066736296352	1.05972680871036	0.365579425776188	0.756037562874227	29	EHD1,RAB21,NDRG4,LRRK2,ARF1,VPS11,MAPK1,RDX,INPP5F,MTMR2,ACTN2
GO:0099518	vesicle cytoskeletal trafficking	GO_VESICLE_CYTOSKELETAL_TRAFFICKING	0.300087966657092	1.05792854215239	0.365725218658892	0.756037562874227	33	NDE1,FYCO1,KIF13A,PAFAH1B1,KIF5B,PRKCZ,WASL,FNBP1L,AP3M2,HTT
GO:0006304	dna modification	GO_DNA_MODIFICATION	0.250142495085421	1.04651109558433	0.365956623454293	0.756037562874227	74	TET1,GNAS,UNG,PRMT7,TDRD5,EXOSC4,ZFP57,EZH2,TET2,AICDA,APOBEC3D,EXOSC3,CTCFL,PLD6,TDRKH,ATRX,APOBEC3H,FTO,BAZ2A,ASCC1,APOBEC1
GO:0034381	plasma lipoprotein particle clearance	GO_PLASMA_LIPOPROTEIN_PARTICLE_CLEARANCE	0.34841288240377	1.06618429184144	0.366114446668149	0.756037562874227	19	EHD1,LRP6,VLDLR,APOC3,LDLR
GO:0002577	regulation of antigen processing and presentation	GO_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION	-0.31904966595291	-1.05823147287419	0.366922739244952	0.757242146105768	23	CCL19,PYCARD,CCL21,LILRB2,THBS1,NOD1
GO:0009190	cyclic nucleotide biosynthetic process	GO_CYCLIC_NUCLEOTIDE_BIOSYNTHETIC_PROCESS	0.307192857648958	1.05873359954629	0.368038961749631	0.759080358608613	30	GUCY1A2,GUCY1B3,GUCY1A3,ADCY7,NPR2,ADCY5,GUCY2C,ADCY8,ADCY9,ADCY4
GO:2000785	regulation of autophagosome assembly	GO_REGULATION_OF_AUTOPHAGOSOME_ASSEMBLY	0.301647967963098	1.05605465212575	0.368523610934057	0.759605331241096	32	LRSAM1,LRRK2,PINK1,RAB1B,RAB3GAP1,PIP4K2C,PIKFYVE,PIP4K2B
GO:0042116	macrophage activation	GO_MACROPHAGE_ACTIVATION	0.307047329382384	1.05823203949478	0.36880506356821	0.759605331241096	30	LBP,CX3CL1,IL4,CSF2,CD93,HMGB1,JMJD6,PRKCE,TLR4,TICAM1,CRTC3
GO:1902667	regulation of axon guidance	GO_REGULATION_OF_AXON_GUIDANCE	-0.277001419088677	-1.04886767760659	0.369028965393741	0.759605331241096	39	SEMA3F,SEMA3C,WNT5A,SEMA3A,SEMA3B,PLXNA2,SEMA3D,SEMA3E,SEMA4B,SEMA4A,PLXNA4,WNT3,PLXNA1,SEMA7A
GO:0051169	nuclear transport	GO_NUCLEAR_TRANSPORT	0.199369622763519	1.03012308055671	0.369196174067271	0.759605331241096	325	OR1D2,NOL6,AGT,ADAR,PIK3R1,RAB30,POM121,NPM1,HSPA9,PRICKLE1,NCBP1,RAB6A,RAB21,SMG6,XPO7,TSC1,STRADA,RANBP6,RAB2B,TSC2,RABL2A,NUP85,RERE,RAB12,SMG1,HMGA1,RAE1,POLA2,GSK3B,RAB1B,JAK2,STRADB,DDX39B,RABL2B,SRSF4,AKAP13,RAB6B,NMD3,XPO4,RHOF,CPSF1,RAB41,NUP188,RAB40AL,NCBP2,TNF,RGS14,SMN1,IPO8,MAPK1,CBLB,HNRNPA2B1,RNPS1,KPNA4,BANF1,RAB9B,SRSF1,ALKBH5,RAB28,KPNA3,ANP32A,MALT1,ATXN1,ZNF384,ENY2,TPR,AAAS,BCL6,KPNA6,DHX38,NXF3,NFKBIA,DDX20,EGF,RAB3A,TGFB3,RBM8A,POM121C,TNPO3,CHTOP
NA	female meiotic division	GO_FEMALE_MEIOTIC_DIVISION	0.328708747154088	1.05983873844663	0.37008192204548	0.760468316211225	23	LFNG,SYCP2,SPIRE1,PRKAR1A,MLH3,EREG,SPIRE2,MLH1,PLK1,PPP2R1A
GO:0010518	positive regulation of phospholipase activity	GO_POSITIVE_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY	0.270179170832065	1.05006826982764	0.370797379068352	0.760468316211225	51	AGT,PLCB2,FLT1,ESR1,PLA2G5,ADCYAP1R1,ARL1,FGFR1,PRKCZ,CAMK2B,NMUR2,PTAFR,PRKCE,CALCR,MARCKS,LPAR2,ABL2,SELE
GO:1901653	cellular response to peptide	GO_CELLULAR_RESPONSE_TO_PEPTIDE	-0.195374943595099	-1.0261328789921	0.37101593625498	0.760468316211225	255	ASS1,GNG8,ATP6V1C2,SSTR3,GPR152,NKX6-1,ALDOB,CYP11A1,SSTR4,RAB31,ATP6V1B1,SSTR2,PTPN2,BAIAP2L2,PRKCI,ANXA5,PKLR,AGTR1,KLF4,XBP1,MEN1,ATP6V0D1,CTNNB1,STAT3,ATP6V1H,IGFBP1,ERRFI1,GNG12,NR4A3,RIPK2,STAR,HIF1A,CPS1,BAIAP2,RAB13,RAB10,ADIPOQ,PRKAR2B,RHOQ,PPARG,DENND4C,AP3S1,CCNA2,NAMPT,PRKAR1B,ADCY2,PRKACG,GNRHR,INPP5K,NOD1,KLF6,ATP6V1A,PDPK1,GNB2,GCGR,MDM2,EDN1,GNG4,GPAM
GO:0042430	indole containing compound metabolic process	GO_INDOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.317962021392728	-1.05462394769015	0.371158911325724	0.760468316211225	23	SLC34A1,TPH1,ATP2B2,GRIN2A,DDC
NA	positive regulation of tyrosine phosphorylation of stat3 protein	GO_POSITIVE_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT3_PROTEIN	-0.281821345198184	-1.0475204727165	0.371459767809791	0.760468316211225	36	IL18,ARL2BP,CLCF1,STAT3,IL6ST,IL20,LEP,IL24,PTGER4,SOCS3,ISL1,IFNA2,FGFR3,IL23R,CRLF1
GO:0042559	pteridine containing compound biosynthetic process	GO_PTERIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	-0.360130892073288	-1.06093380653059	0.371512672337294	0.760468316211225	15	GART,MTHFD1L,PTS,DHFR
GO:0001558	regulation of cell growth	GO_REGULATION_OF_CELL_GROWTH	-0.187447507065469	-1.02293022302021	0.371591349079042	0.760468316211225	358	SEMA3F,SGK2,SEMA3C,SFN,ING1,SYT4,TAF9B,BDKRB1,NKX6-1,FOXM1,NPR1,WT1,TGFBR1,IGFBP4,WNT5A,TP53TG5,ULK2,SFRP2,CTGF,HTRA1,SPOCK1,SYT17,EFNA5,PAPPA2,ADAM15,SGK1,CYR61,CRIM1,WISP2,RTN4,CDKN2C,SEMA3A,SEMA3B,GAS2L1,AGTR1,IGFBP1,PLXNA2,SLIT3,CDKN1A,EGFR,EXOSC2,F2,CLSTN3,RERG,ST7L,FBP1,SEMA3D,CDK5,NOV,PPARG,RND2,S100A9,FGF13,CDH4,DCUN1D3,LMX1A,EBAG9,PSMD10,CPNE6,RPS6KA1,SEMA3E,SERTAD3,GAL,SEMA4B,NRCAM,FAM107A,ACVR1B,SEMA4A,FSTL4,GNG4,WDR36,CDC42,PLXNA4,IL17RB,HNF4A,H2AFY2,INHBA,TTL,ABL1,SIRT1,DERL2,SYT1,RNF6,RAB11A,MMP14,BCL2,WISP3,NRG1,WNT3,DNAJC2,SH3BP4,DDR1,PLXNA1,MAP2K5,MUC12,WISP1,CRABP2,SEMA7A,RIMS2,SPP1
GO:0042158	lipoprotein biosynthetic process	GO_LIPOPROTEIN_BIOSYNTHETIC_PROCESS	-0.235600303172847	-1.03957770381988	0.37166223961974	0.760468316211225	81	APOA2,NMT2,ZDHHC20,PIGV,PIGW,PIGX,ALOX12B,PLAUR,PIGU,GOLGA7,MAP6D1,ABCA1,ZDHHC8,PIGZ,ZDHHC3,PIGF,PIGQ,PORCN,ZDHHC23,PIGK
GO:0097306	cellular response to alcohol	GO_CELLULAR_RESPONSE_TO_ALCOHOL	-0.223883376810124	-1.03555791395061	0.371685221463042	0.760468316211225	106	ASS1,SSTR3,MLC1,AQP1,SSTR2,KLF4,CTNNB1,ERRFI1,PIM1,EGFR,STAR,MSX2,LRP8,MSTN,ABCA1,CCNA2,HMBS,CDH1,MYOD1,KLF6,SPTBN2,MSN,ZNF703,CYP7A1,INHBA,PAWR,ATP2B1,SERPINF1,IL10,NTS,NRIP1,CCDC62
GO:0043153	entrainment of circadian clock by photoperiod	GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK_BY_PHOTOPERIOD	0.364222937938106	1.06423575902597	0.372121550041818	0.760468316211225	16	NR2F6,USP2,PPP1CB,MTA1,PER1,PPP1CC,CRY2
GO:1900274	regulation of phospholipase c activity	GO_REGULATION_OF_PHOSPHOLIPASE_C_ACTIVITY	0.288473441280037	1.05136037772987	0.372131680699599	0.760468316211225	38	AGT,PLCB2,FLT1,ESR1,ADCYAP1R1,FGFR1,PTAFR,PRKCE,CALCR,LPAR2,ABL2,SELE
GO:0045815	positive regulation of gene expression epigenetic	GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC	0.255944425943171	1.04532400841964	0.372326733546078	0.760468316211225	65	TET1,PHF2,ZNRD1,TWISTNB,HIST1H3G,HIST1H3B,HMGA1,HIST1H4F,KAT2A,H3F3A,TAF1B,EP300,AICDA
GO:1990776	response to angiotensin	GO_RESPONSE_TO_ANGIOTENSIN	0.357654138390592	1.06248732125749	0.37315875613748	0.761705502218773	17	AGT,CAMK2A,GSK3B,AGTR2,CA2
GO:1990138	neuron projection extension	GO_NEURON_PROJECTION_EXTENSION	-0.261536606877446	-1.04290618229732	0.374270455416094	0.763197425194042	49	SEMA3F,FLRT3,ULK2,FMOD,SEMA3A,SLIT3,FLRT1,EPYC,EMX1,CDK5,EIF2AK4
GO:0016042	lipid catabolic process	GO_LIPID_CATABOLIC_PROCESS	0.207392718165525	1.03130104835902	0.374343122102009	0.763197425194042	231	SLC25A17,DECR1,IVD,PLCB2,PPARD,LPIN1,DDHD2,ACOX3,CLPS,PLCXD3,ACAD9,ACADM,PAFAH1B1,MMAA,ACAD10,LIPN,APOC3,PLD1,PLA2G4C,PNPLA1,FABP9,PLCH1,LIPJ,PLA2G5,CEL,ABHD2,FABP7,PLCE1,ABHD4,CYP27B1,ABHD6,PLCB4,NEU3,PLA2G15,MGLL,SMPD4,HRASLS,HADH,LIPG,ECI2,ETFA,NCEH1,LIPF,PEX7,ACOT8,HADHB,PLA2G4E,PLD6,PCCB,FABP3,PLCD3,ECHS1,PLCG1,CYP3A4,PLA2G7,GCDH,PAFAH2,ACADVL,PCCA,NAPEPLD,NAGA,HADHA,GPCPD1,PNPLA6,INPP5F,SCP2,PLA2G4D,PNLIPRP3,OC90,APOA5,MCEE,MT3,FABP12,MUT,ACADSB,PLA1A,SMPD1,PNPLA2,AKR1D1,SIRT2,CRABP1
GO:0006656	phosphatidylcholine biosynthetic process	GO_PHOSPHATIDYLCHOLINE_BIOSYNTHETIC_PROCESS	0.320567333306734	1.05540470072373	0.375144519278413	0.764368312282771	25	CHAT,LPIN1,PCYT1A,CHPT1,LCAT
GO:0055069	zinc ion homeostasis	GO_ZINC_ION_HOMEOSTASIS	-0.324945021882759	-1.0519981465944	0.376263122285515	0.766183708174859	21	SLC39A8,SLC39A6,SLC39A10,S100A9,SLC30A8,ATP7B,SLC39A4,SLC30A7,SLC30A4
GO:1901068	guanosine containing compound metabolic process	GO_GUANOSINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.275682069971008	-1.04387195357906	0.376617271791198	0.766439151245493	39	NUDT18,GUK1,NME9,IMPDH2,TJP2,MOCS3,AMPD2,RHOQ,MAGI3,CASK,MPP3,DLG1
GO:0031641	regulation of myelination	GO_REGULATION_OF_MYELINATION	-0.297364141328053	-1.0478395204682	0.376843967709831	0.766439151245493	29	RARA,TNFRSF21,TG,CTNNB1,EIF2AK3,MAG,HGF,DLG1,NRG1,KLK8,PARD3,WASF3
GO:0070925	organelle assembly	GO_ORGANELLE_ASSEMBLY	0.192532563385822	1.02456322794336	0.378100888383388	0.766727688787185	437	EHD1,SHANK3,CEP192,DDX3X,TUBGCP5,WDR62,DNAI2,ERAL1,OBSCN,POGZ,BIRC8,NPM1,NRXN1,TTBK2,LDB3,CLASP1,CFLAR,C1QBP,ATG14,TP53INP2,MFN2,RPL3L,CENPA,MDN1,PAFAH1B1,NEK1,VPS4A,SBDS,C2CD3,MRTO4,ZMYND10,CAPN3,ABLIM1,FABP9,TUBGCP2,BMP10,ATG16L1,GOLGA2,LMOD1,LMOD3,IFT172,DYNC1H1,ABLIM3,RP1,KIF27,SYT7,FASTKD2,OBSL1,PTEN,ABT1,CHMP7,TCAP,DMD,PIK3C3,PRKAR1A,VPS37B,WIPI2,MYPN,TTN,BBS9,TMOD1,MRPL20,FNBP1L,CCDC113,MYL2,DBNL,KIFC1,EDC3,LSM4,FARP2,NKX2-5,DHX30,PLK4,NCOR1,ATG9A,RPS14,DNAI1,P2RX7,FHOD3,LIMD1,ICK,MAP1LC3A,MYLK3,PATL1,TUBGCP6,NME5,VPS37C,MKKS,TMEM175,LAMA5,WDR45,CFL2,CHMP6,TMEM17,HAUS8,ATG16L2,TRIM59,FOXJ1,TUBGCP3,SPAG1,ATXN2L,UBE2B,RRP7A
GO:0000027	ribosomal large subunit assembly	GO_RIBOSOMAL_LARGE_SUBUNIT_ASSEMBLY	-0.324486157806371	-1.05051259019134	0.378401972980641	0.766727688787185	21	RPL24,RPL38,RPL3,RSL24D1,BRIX1,RPL5
GO:0070542	response to fatty acid	GO_RESPONSE_TO_FATTY_ACID	-0.236200471683624	-1.03697610555558	0.378630149747316	0.766727688787185	79	ASS1,CCL19,LIPC,FFAR3,CTGF,CAT,P2RY4,CCL21,AKR1C3,DGAT2,CPS1,ADIPOQ,CCNB1,PPARG,PTGER2
GO:0033198	response to atp	GO_RESPONSE_TO_ATP	0.313437677117454	1.05205740191661	0.378678827170668	0.766727688787185	27	TRPV1,DGKQ,PANX1,PTEN,SLC8A1,P2RX7,SOD1,SSH1
GO:0060716	labyrinthine layer blood vessel development	GO_LABYRINTHINE_LAYER_BLOOD_VESSEL_DEVELOPMENT	-0.33862224213886	-1.05157575097397	0.378935962726189	0.766727688787185	18	PLCD1,TMED2,CYR61
GO:0045638	negative regulation of myeloid cell differentiation	GO_NEGATIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	-0.240829394710848	-1.03622193232595	0.379416389197188	0.766727688787185	71	CCL3,RARA,PTPN2,HOXA7,HIST1H4C,LEO1,GAS2L1,CTNNB1,TJP2,ADIPOQ,HIST1H4D,ZNF675,CLDN18,HIST1H4E,CARTPT,HOXB8,MAFB,MYC,TRIB1,INHBA,PF4,GPR55,TLR3,KLF13,LTF,PTK2B
GO:0048747	muscle fiber development	GO_MUSCLE_FIBER_DEVELOPMENT	0.286985078312206	1.04593594127183	0.380280417735699	0.766727688787185	38	XK,DNER,CACNA2D2,TCAP,DMD,TTN,MYL2,FLNC,VEGFA,HOMER1
GO:0010632	regulation of epithelial cell migration	GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.218753024344066	1.03214607446338	0.380733637339056	0.766727688787185	155	AMOT,AGT,PTPRM,NRP1,PDGFB,HDAC9,CSNK2B,CLASP1,ATOH8,AAMP,ROCK2,ITGB3,BMPER,SASH1,BMP10,MACF1,SP100,CTSH,FGF1,STARD13,TGFBR2,GLIPR2,AGTR2,DLL4,FGFR1,AMOTL1,CCR2,PTPRG,IL4,PDCD6,SEMA5A,TEK,HDAC6,VEGFA,ETS1,EPB41L4B,HSPB1,SOX9,HYAL1,PLCG1,HMGB1,PRKCE,BCAS3,PFN2,PROX1,CAPN7,HDAC5,EMP2,NR2F2
GO:1901071	glucosamine containing compound metabolic process	GO_GLUCOSAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	-0.311660318247727	-1.04630773179558	0.380932537941925	0.766727688787185	24	CHI3L1,AMDHD2,PGM3,EXTL2
GO:1903651	positive regulation of cytoplasmic transport	GO_POSITIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT	-0.194111821149425	-1.02176653464524	0.381105178717025	0.766727688787185	260	GPR26,HAP1,SFN,EZR,DPCR1,CCL19,BDKRB1,NLGN1,IL18,TGFBR1,BMP4,SFRP2,TNFSF14,PEMT,TDRD12,SNCA,IPO5,XBP1,UBL4B,EDAR,WDR75,TOR1A,SULF2,WDR46,BCAP31,SH3GLB1,HDAC3,EGFR,F2,UBE2L3,LEP,DAB2,ANXA13,STX18,SORL1,CDKL2,UNC13B,RAPGEF3,CTSK,ZDHHC8,CDH1,NLRP12,TLR9,HNMT,CTDSPL2,BAX,ASPH,F2RL3,PDPK1,MSN,NKAP,F2R,HSP90AA1,PKD2,RHOA,TLR2,NODAL,MDM2,RNASE2
GO:0046068	cgmp metabolic process	GO_CGMP_METABOLIC_PROCESS	0.326222913971138	1.05182379413068	0.381121193196429	0.766727688787185	23	PDE5A,GUCY1A2,GUCY1B3,GUCY1A3,NPR2,PDE2A,GUCY2C
GO:0045922	negative regulation of fatty acid metabolic process	GO_NEGATIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS	-0.338130218988917	-1.0500477957808	0.381189728031206	0.766727688787185	18	CNR1,APOC1,ACADL
GO:0030705	cytoskeleton dependent intracellular transport	GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT	0.232530860477581	1.03361389278246	0.381929866822671	0.766727688787185	105	RHOT2,NDE1,FYCO1,KIF13A,BBS12,PAFAH1B1,APP,RAB6A,RAB21,KIF5B,KIF1A,PEX14,IFT27,KIF16B,MYO10,PRKCZ,WASL,FNBP1L,SPG11,KIF1C,TMEM201,ARHGAP21,SOD1,ICK,SYNE2,MAP1S,AP3M2,HTT
GO:0003181	atrioventricular valve morphogenesis	GO_ATRIOVENTRICULAR_VALVE_MORPHOGENESIS	-0.349789610533831	-1.05102975927241	0.382081087516505	0.766727688787185	16	BMP2,CYR61,ACVR1
GO:0044849	estrous cycle	GO_ESTROUS_CYCLE	0.34954428651277	1.0545721868424	0.382160164881074	0.766727688787185	18	OPRL1,ADRB2,OPRK1,MMP7,ESR2,ETS1,NCOA1,GNRH1
GO:0090087	regulation of peptide transport	GO_REGULATION_OF_PEPTIDE_TRANSPORT	0.20542295076261	1.02752852580923	0.382161775697897	0.766727688787185	244	LRP5,GNAS,BAD,PPARD,TRPM4,BMP8A,RBCK1,PYDC2,SYT9,ITPR1,NRXN1,PDE8B,RAPGEF4,TIAM1,CACNA2D2,DRD2,CDK16,GHSR,ADRA2C,C8orf4,GIPR,STX1A,GJA1,GLP1R,HMGCR,CHD7,SYT7,PDE4C,JAK2,REST,SLC25A4,SIRT4,UCN,PFKM,IRS1,ADCY5,GCK,ANO1,HADH,STX4,GLUD1,CACNA1C,IL18R1,KCNA5,TNF,GABBR1
GO:0046597	negative regulation of viral entry into host cell	GO_NEGATIVE_REGULATION_OF_VIRAL_ENTRY_INTO_HOST_CELL	-0.337825398781851	-1.04910119069032	0.382338281503955	0.766727688787185	18	IFITM2,TRIM11,MID2,FCN3
GO:0009310	amine catabolic process	GO_AMINE_CATABOLIC_PROCESS	0.344284806291193	1.0535518946798	0.382588392261508	0.766727688787185	19	DMGDH,ALDH7A1,HAAO,SARDH,IDO1,SAT2
GO:0042273	ribosomal large subunit biogenesis	GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS	-0.266947649738399	-1.03917301500016	0.382782112102885	0.766727688787185	44	RPL24,NOC2L,RPL38,RPL35,RPL3,RSL24D1,NLE1,BRIX1,RPL5,NSA2,RPL26,PES1,RPF2,RPL23A,BOP1,RPL14
GO:0001974	blood vessel remodeling	GO_BLOOD_VESSEL_REMODELING	0.3039334485313	1.04750011588413	0.383032668770407	0.766727688787185	30	AGT,ATP7A,EPAS1,AGTR2,DLL4,CCR2,FGF8,AXL,BAK1,MEF2C,ACE,FOXC2,CSRP3
GO:0098534	centriole assembly	GO_CENTRIOLE_ASSEMBLY	-0.337555716390966	-1.04826370446695	0.383183443493336	0.766727688787185	18	CEP135,CETN2,CCP110,CEP152,E2F4
GO:0007622	rhythmic behavior	GO_RHYTHMIC_BEHAVIOR	-0.342944270796968	-1.04882791315578	0.383246095946706	0.766727688787185	17	MC3R,HCRTR2,STAR
GO:0034724	dna replication independent nucleosome organization	GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION	0.2831288010327	1.0432192765466	0.38325625090331	0.766727688787185	40	NASP,CENPK,NPM1,CENPA,HIST1H4F,H3F3A,CENPN,ASF1B,ATRX,CENPI,UBN1,ASF1A,HIST1H4A,CENPO,CENPT
GO:0010595	positive regulation of endothelial cell migration	GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.257995375981995	1.03968194847154	0.383513815288092	0.766727688787185	61	AMOT,AGT,NRP1,PDGFB,HDAC9,ATOH8,AAMP,ROCK2,ITGB3,SASH1,FGFR1,AMOTL1,CCR2,PDCD6,SEMA5A,TEK,VEGFA,ETS1,HSPB1
GO:0042310	vasoconstriction	GO_VASOCONSTRICTION	-0.298841089524004	-1.04408573505007	0.383586733455436	0.766727688787185	28	P2RX1,DRD5,HTR1B,ADRA1D,BDKRB2,EDNRB
GO:0000083	regulation of transcription involved in g1 s transition of mitotic cell cycle	GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE	-0.31110024813221	-1.04442746132834	0.383915255724186	0.766727688787185	24	TYMS,FBXO5,DHFR,E2F4,BRD4,CDT1,CDC6,PCNA
GO:0007520	myoblast fusion	GO_MYOBLAST_FUSION	-0.332129420524539	-1.04605955757886	0.384008862244233	0.766727688787185	19	CDON,KCNH1,FER1L5,NPHS1,CAPN2,MYOD1
GO:0003283	atrial septum development	GO_ATRIAL_SEPTUM_DEVELOPMENT	0.360773686927024	1.05415727168898	0.38425796859028	0.766727688787185	16	ANK2,DAND5,GJA5,TBX5,TBX20,NKX2-5,HEY2
GO:0060761	negative regulation of response to cytokine stimulus	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS	-0.272579625977891	-1.03797677201596	0.384501679731243	0.766727688787185	40	PTPN2,KLF4,SLIT3,IL6ST,PELI3,ADIPOQ,IRAK3,PPARG,NR1H3,ZNF675
GO:0048286	lung alveolus development	GO_LUNG_ALVEOLUS_DEVELOPMENT	-0.272570824875317	-1.03794325762541	0.384591265397536	0.766727688787185	40	PDPN,BMP4,WNT5A,FGFR2,FOXF1,FOXA1,ERRFI1,HOPX
GO:0035872	nucleotide binding domain leucine rich repeat containing receptor signaling pathway	GO_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_SIGNALING_PATHWAY	-0.307559089788779	-1.04327881155184	0.385071740897805	0.766727688787185	25	IRAK1,RIPK2,CHUK,UBA52,IKBKG,NOD1,UBB,TAB2
GO:0090140	regulation of mitochondrial fission	GO_REGULATION_OF_MITOCHONDRIAL_FISSION	0.360384633402008	1.0530204825679	0.385819161787938	0.766727688787185	16	DDHD2,LRRK2,PINK1,MARCH5,DHODH,BNIP3,PPARGC1A
GO:0030865	cortical cytoskeleton organization	GO_CORTICAL_CYTOSKELETON_ORGANIZATION	-0.282990920834992	-1.03727253515184	0.385976991071825	0.766727688787185	34	EZR,NLGN1,CALR,RAB13,RHOQ,CDK5,WIPF2,LLGL1,DLG1,EHD2
GO:0097421	liver regeneration	GO_LIVER_REGENERATION	-0.331600865828344	-1.04439484600112	0.386007211434033	0.766727688787185	19	PTPN3,CEBPB,PRMT5,SULF2,RAPGEF3,FAS
GO:0036314	response to sterol	GO_RESPONSE_TO_STEROL	-0.314486203254127	-1.04309527193595	0.386106233538191	0.766727688787185	23	CCL3,MLC1,TGFBR1,LRP8,SMAD2,ABCA1,CYP7A1,INHBA
GO:0018209	peptidyl serine modification	GO_PEPTIDYL_SERINE_MODIFICATION	0.221379746257376	1.02937470035484	0.386183733058786	0.766727688787185	140	PRKACA,AKT2,MAPKAPK2,PDGFB,MAST3,TTBK2,MKNK1,DMPK,ULK1,LRRK2,CAMK2A,HIPK2,TAF1,PINK1,PRKX,MAPKAPK3,SMG1,GSK3B,PRKAA2,PRKCH,TGFBR2,TLK2,MAPKAPK5,PRKCZ,GALNT2,MTOR,IKBKB,MAPK1,CDK1,PKN1
GO:0007389	pattern specification process	GO_PATTERN_SPECIFICATION_PROCESS	-0.184760089912457	-1.01742419134873	0.3867243461895	0.766727688787185	390	SEMA3F,PAX7,SEMA3C,WNT6,HOXA6,TBX6,PAX8,NKX3-2,DLX1,NKX6-1,OSR1,TRAF3IP1,BICC1,WT1,CYP26B1,CDON,TGFBR1,IFT57,BMP4,WNT5A,SFRP2,HOXA3,BMP2,T,HOXA7,WNT2B,RFX4,FGFR2,BBS7,TMED2,FOXF1,FOXA1,CRB2,HOXC10,GBX2,SEMA3A,ACVR1,OTX2,OTX1,COBL,CTNNB1,BMPR1B,PLXNA2,FEZF1,EVX1,NLE1,WDR19,MSX2,WNT7B,HIF1A,LEFTY1,EMX1,BMP5,SMAD2,ZIC3,IRX1,APC2,NEK8,DYNC2LI1,IFT52,XRCC2,IRX4,SEMA3E,ARL13B,BAX,ASPH,ACVR2B,MID1,TULP3,PKD2,HOXB8,MAFB,NODAL,BTG2,BASP1,GNA13,EDN1,STIL,TTC8
NA	transcription from rna polymerase iii promoter	GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER	0.287690643357182	1.0420330508317	0.386805945290295	0.766727688787185	37	BRF1,GTF3C5,GTF3C1,SNAPC3,ELL,ZC3H8,POLR3F
GO:0031293	membrane protein intracellular domain proteolysis	GO_MEMBRANE_PROTEIN_INTRACELLULAR_DOMAIN_PROTEOLYSIS	0.360072722279498	1.05210909853456	0.386822785986432	0.766727688787185	16	NCSTN,MBTPS1,PSENEN,NFKB1,RHBDD1,APH1A,PSEN2
NA	regulation of interleukin 1 secretion	GO_REGULATION_OF_INTERLEUKIN_1_SECRETION	-0.290209708686836	-1.03951127881472	0.386961722488038	0.766727688787185	31	CCL3,GSDMD,CCL19,WNT5A,PYCARD,SAA1,NLRP3,NLRP12,IFNAR1
GO:0061951	establishment of protein localization to plasma membrane	GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE	-0.230584124731049	-1.03012960616171	0.387253521126761	0.766727688787185	87	EZR,PIP5K1A,S100A10,RAB31,PRKG2,AMN,KRT18,TMED2,ANXA2,SPTBN4,TSPAN15,RAB13,RAB10,TNFRSF1A,MPP5,GOLGA7,TSPAN5,GCC2,CDH1,KCNB1,INPP5K,RILPL2,F11R
GO:0033363	secretory granule organization	GO_SECRETORY_GRANULE_ORGANIZATION	-0.310291818509832	-1.04171339696088	0.38749013071322	0.766727688787185	24	AGFG1,RAB38,RFX2,ABCA1,F2RL3,F2R,TMF1,BLOC1S3,SPACA1
GO:0060393	regulation of pathway restricted smad protein phosphorylation	GO_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION	-0.251190217380884	-1.03382730060756	0.388570258090946	0.766727688787185	57	GDF5,TGFBR1,BMP4,BMP2,SNX25,GDF10,ACVR1,LEFTY1,MSTN,BMP5,DAB2
GO:0031529	ruffle organization	GO_RUFFLE_ORGANIZATION	-0.330961336009721	-1.0423806122784	0.388635475042356	0.766727688787185	19	PIP5K1A,LIMA1,CCL21,TPM1,INPP5K,ARHGEF26,RAC1,CORO1B
GO:0090200	positive regulation of release of cytochrome c from mitochondria	GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA	0.314728764623009	1.04654047016007	0.388712664331946	0.766727688787185	26	BAD,MOAP1,PPIF,PINK1,APOPT1,TNFSF10,FAM162A,BID,BAK1,HRK,BMF,BNIP3
NA	regulation of stat cascade	GO_REGULATION_OF_STAT_CASCADE	-0.212157518003731	-1.0249809462019	0.388720109760878	0.766727688787185	139	IL18,FLRT3,ARL2BP,PTPN2,LRRC4B,SOCS1,CLCF1,FLRT2,LRRC19,STAT3,IL6ST,IFNA14,FLRT1,IL20,TNFRSF1A,PODNL1,LEP,PIGU,CDK5,IFNE,IL24,IFNA16,IL5,DCN,FLT3,F2R,NYX,HNF4A,PTGER4,SOCS3,RET,IL10,ISL1,CYP1B1,LRRTM4,HGS,PTK2B,RTN4RL2,IFNA2,NEUROD1,LRRC4C,HPX,FGFR3,IGF1,IL23R,CRLF1
GO:0030004	cellular monovalent inorganic cation homeostasis	GO_CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS	-0.229917295331091	-1.02916989251994	0.388968498202918	0.766727688787185	88	SGK2,SLC26A9,CFTR,ATP6V1C2,TMPRSS3,ATP6V1B1,SLC4A4,SGK1,RAB38,ATP6V0D1,ATP6V1H,SLC17A7
GO:0021602	cranial nerve morphogenesis	GO_CRANIAL_NERVE_MORPHOGENESIS	-0.317702389614781	-1.04157177323055	0.3890043991158	0.766727688787185	22	SEMA3F,HOXA3,SEMA3A,CHRNB2
GO:0009124	nucleoside monophosphate biosynthetic process	GO_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS	0.247842424485699	1.03422075606654	0.389143219354157	0.766727688787185	73	TK1,ATP5L,UPP2,AK1,PPAT,UCKL1,ATP5A1,ATP5G2,ATP5D,AK4,ATP5O,ATP5B,ADA,ATP5G3,ADSSL1
GO:0002690	positive regulation of leukocyte chemotaxis	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CHEMOTAXIS	-0.235464527145117	-1.03115822265689	0.389146492066081	0.766727688787185	78	CCL3,CCL19,WNT5A,CCR6,TNFSF14,ANO6,CALR,CXCL1,F7,CCL21,CSF1,C5AR1,RARRES2,CMKLR1,THBS1,CCL4,THBS4,CXCL5,SWAP70,PF4
GO:0071824	protein dna complex subunit organization	GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION	0.210641988891862	1.02560576068616	0.389156706068811	0.766727688787185	196	SMARCB1,CUL4A,HILS1,NASP,CENPK,POGZ,NPM1,PAF1,HIST1H2BO,CENPA,DMC1,DACH2,TCF4,HIST1H3G,TAF1,HIST1H3B,HMGA1,HELLS,SMARCD3,HIST1H4F,HP1BP3,HIST1H2BC,DACH1,KAT6A,PSME4,GTF2H3,H3F3A,HIST1H2BA,TAF1B,EP300,H2BFWT,CENPN,HIST1H3E,GTF2H5,ASF1B,SOX9,HEY2,ATRX,HIST2H2BE,CENPI,UBN1,ANP32E,TSPYL5,ASF1A,H1F0,HIST2H2BF,H1FX,KAT6B
NA	asymmetric protein localization	GO_ASYMMETRIC_PROTEIN_LOCALIZATION	-0.335984190362264	-1.04338340288555	0.389337956441651	0.766727688787185	18	DLG5,RAB10,MPP5,SHROOM2,DYNC2H1,WNT7A,ARF4
GO:0030099	myeloid cell differentiation	GO_MYELOID_CELL_DIFFERENTIATION	-0.204213764231609	-1.02298537061083	0.389376745590418	0.766727688787185	178	CDKN2B,TNFSF11,CCL19,KDM1A,EPB42,BMP4,PTPN2,GATA3,RPS19,BATF3,ANXA2,PRTN3,CTNNB1,CEBPA,CSF1,SNX10,SH3PXD2A,L3MBTL3,IRF4,SOX6,CASP3,TNFSF9,VPS33A,CEBPG,MT1G,PPARG,CBFB,CLEC5A,NKX2-3,ETV2,EPHA2,NKAP,DNASE2,JUNB,IL25,OSTM1,CDC42,FAM20C,CEBPE,IFI16,INHBA,RPS6,SIRT1,PSEN1,ARID4A
GO:1902803	regulation of synaptic vesicle transport	GO_REGULATION_OF_SYNAPTIC_VESICLE_TRANSPORT	-0.29776028063298	-1.04030962398304	0.389478562129002	0.766727688787185	28	NLGN1,SYN1,RIMS4,SNCA,TOR1A,CDK5,UNC13B,STXBP1
GO:0019221	cytokine mediated signaling pathway	GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY	-0.183313304428588	-1.01605554811354	0.389514066496164	0.766727688787185	418	TNFRSF8,IFITM2,KRT8,EDA2R,IL17REL,CCL3,TNFSF11,CCL19,FLRT3,IRAK4,TNFRSF21,OSMR,CCR6,TNFSF14,TNFRSF11B,DUOX2,KRAS,KRT18,LRRC4B,HLA-DRB5,IL13RA1,MT2A,SOCS1,CLCF1,FLRT2,TXNDC17,CARD14,IRAK1,CXCL1,LRRC19,EDAR,TRIM62,STAT3,TJP2,IL6ST,PYCARD,CCL21,CEBPA,MST1R,RIPK1,CSF1,IFNA14,FLRT1,IL36B,TRADD,LRP8,UBA52,IRF7,IRF4,TNFRSF1A,ADIPOQ,IL1F10,PODNL1,IRAK3,LEP,IL17RC,TRIM38,PSMB11,IFNE,TNFRSF25,FAS,PSMD10,IL1RAPL2,IFNA16,ZNF675,IL1R1,CLDN18,IL5,CMKLR1,DCN,IFNAR1,FLT3,PLP2,MID1,PSMD5,CCL4,IL2RA,PSMD13,NYX,PSMB5,FOXO3,HLA-DRB1,CCL18,IL1RAP,IL17RB,UBB,IFI6,IL36G,F3,CXCL5,SOCS3,SIRT1,EDARADD,IL20RB,MPL,PSMA6,IL4R,PSMA4,PF4
NA	modulation of synaptic transmission	GO_MODULATION_OF_SYNAPTIC_TRANSMISSION	0.200864305507005	1.02343319488798	0.390255621756679	0.766962621570768	286	PLCL1,LAMA2,CPEB3,SHANK3,AGT,NLGN3,USP46,PRKACA,LRRTM2,GPM6B,NRXN1,DLG4,SLC24A2,DRD4,DMPK,LRRK2,CAMK2A,CPLX3,HRH2,KIF5B,SHANK1,CACNA2D2,ATP1A2,DRD2,VAMP2,SLC6A1,CEL,PINK1,STX1A,ARF1,SNCG,RASGRF1,GSK3B,RAPGEF2,PTEN,PATE4,ABHD6,RAB3GAP1,UCN,GRIA1,PPP1R9A,NFATC4,NPS,GRIK5,STX4,PRKCZ,PAIP2,KLHL24,OPHN1,CREB1,GABBR1,NPY5R,CAMK2B,RGS14,SYT12,MAPK1
GO:0000305	response to oxygen radical	GO_RESPONSE_TO_OXYGEN_RADICAL	0.359215880260047	1.04960546182761	0.390335470681163	0.766962621570768	16	ATP7A,PRDX2,SOD2,SOD1,CCS,MT3,SOD3,UCP3,NOS3,PRDX1,UCP2
GO:0048596	embryonic camera type eye morphogenesis	GO_EMBRYONIC_CAMERA_TYPE_EYE_MORPHOGENESIS	0.32416388469429	1.04518497173823	0.390378751699056	0.766962621570768	23	ZEB1,TBX2,KDM2B,HIPK2,PAX6,PROX1,TH,TWIST1
GO:0036148	phosphatidylglycerol acyl chain remodeling	GO_PHOSPHATIDYLGLYCEROL_ACYL_CHAIN_REMODELING	-0.347698859688646	-1.04474757909513	0.390544840574063	0.766962621570768	16	PLA2G2A,PLA2G2D,PLA2G4F,PLA2G2F,PLA2G4A
GO:0090068	positive regulation of cell cycle process	GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS	0.206861850130655	1.02463684006775	0.391465344273527	0.767890649122079	224	CUL4A,LRP5,TAS2R13,PPP2R5C,DDX3X,PRKACA,PCID2,PDGFB,NPM1,APP,ROCK2,CREBBP,CCND1,SVIL,DRD2,MAD2L1,GOLGA2,PLAGL1,SMARCD3,PTEN,RRP8,TFDP2,MED25,CNOT6L,GORASP1,E2F8,TGFA,CNOT4,FAM83D,EP300,TAS1R2,KCNA5,ANAPC11,ANKRD17,PLK4,CDKN1B,CDK1,GADD45A,CDC25C,DLGAP5,SFPQ,PRDM9,CNOT8,ARID3A,RDX,ATRX,FOXO4,TPR,PRKCE,FGF8,UBE2B,EGF,PROX1,ESPL1,MSX1,MED1,CNOT1,CYP1A1
GO:0045639	positive regulation of myeloid cell differentiation	GO_POSITIVE_REGULATION_OF_MYELOID_CELL_DIFFERENTIATION	-0.238773226148745	-1.03032756838861	0.391758305359417	0.767890649122079	72	PRKCA,TNFSF11,KDM1A,RIPK1,CSF1,HIF1A,IL20,LEP,SCIN,SLC9B2,IL5,HMGB2,ACVR1B,FOXO3,TESC,MAPK11,TRIB1,INHBA,PF4,JUN,FES,FOS,CALCA,GPR68,ARNT
GO:0003009	skeletal muscle contraction	GO_SKELETAL_MUSCLE_CONTRACTION	0.310717923960677	1.04292851713706	0.391773345786862	0.767890649122079	27	ADRB2,DMPK,TCAP,TNNI3,MYH7,IKBKB,HOMER1,TNNC2,TNNT3,MYH8,TNNT1,RPS6KB1
GO:0060411	cardiac septum morphogenesis	GO_CARDIAC_SEPTUM_MORPHOGENESIS	-0.26426094295405	-1.03373857427244	0.391929927270271	0.767890649122079	45	RARA,WNT5A,FGFR2,CYR61,SOX11,ACVR1,PARVA,MSX2,WHSC1
NA	regulation of glucose import in response to insulin stimulus	GO_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS	0.358660331464369	1.04798218434379	0.392379890344764	0.768030968235646	16	PIK3R1,AKT2,PIK3R3,IRS1
GO:0046856	phosphatidylinositol dephosphorylation	GO_PHOSPHATIDYLINOSITOL_DEPHOSPHORYLATION	0.327955893980425	1.04461310850103	0.392664469444496	0.768030968235646	22	MTMR1,INPP5J,INPPL1,PTEN,INPP5D,INPP5A,SACM1L,INPP5F,MTMR2,SYNJ1
NA	regulation of n methyl d aspartate selective glutamate receptor activity	GO_REGULATION_OF_N_METHYL_D_ASPARTATE_SELECTIVE_GLUTAMATE_RECEPTOR_ACTIVITY	0.364734983728232	1.04805411304274	0.392776817412963	0.768030968235646	15	NLGN3,NRXN1,DLG4,RASGRF1
GO:0051031	trna transport	GO_TRNA_TRANSPORT	0.301783811495686	1.04009143791599	0.393064954489904	0.768030968235646	30	NOL6,POM121,NUP85,RAE1,NUP188,TPR,AAAS,POM121C,NUP214,NUP35
GO:0045683	negative regulation of epidermis development	GO_NEGATIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT	-0.347054918939109	-1.04281269918278	0.393142411844925	0.768030968235646	16	HOXA7,GRHL2,MSX2,CDH3
GO:0090630	activation of gtpase activity	GO_ACTIVATION_OF_GTPASE_ACTIVITY	0.251144267491967	1.03183794213462	0.39364699253416	0.768570636235488	67	AKT2,ADPRHL1,SGSM1,TIAM1,TSC1,EPHA1,RASGRF1,TBC1D13,RUNDC1,TBC1D4,RABGAP1L,TBC1D10B,TBC1D8,SYDE1,TBC1D21,TBC1D26,BCAS3,FOXJ1,TBC1D30,NTRK3
GO:0008344	adult locomotory behavior	GO_ADULT_LOCOMOTORY_BEHAVIOR	0.244310025319634	1.02936544720073	0.394171214008738	0.769148003683137	77	SCN1A,PREX2,DRD4,PAFAH1B1,APP,TSC1,ATP1A2,DRD2,HIPK2,CHD7,SNCG,CLN8,TMOD1,PARK7,NPC1,EPHA4,FXN,FGF12,ATP1A3,GIGYF2,NTF4,HOXD10,GLRA1,EN1,CNTN2,KLHL1,PUM1,CXCL12,MAPT,SLITRK6,CACNA1A,GRIN1,MECP2
GO:0033674	positive regulation of kinase activity	GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY	0.191149088206175	1.01930592026481	0.394439244449218	0.769225085061453	448	CCND2,MADD,AGT,MARK2,RAPGEF1,PRKACA,BAD,TAOK2,PDE5A,MAPKAPK2,FBXW7,PDGFB,ATG14,TNIK,LPAR3,DRD4,DVL2,EEF1A2,TIAM1,ALS2,FLT1,ADRB2,ZAK,DIRAS2,UNC119,LRRK2,CALM3,VLDLR,ITGB3,CCND1,MAP3K15,STRADA,TAOK3,SASH1,CRKL,DRD2,ZEB2,ADRA2C,PINK1,MAPKAPK3,NKX3-1,PLCE1,FGF1,RAPGEF2,JAK2,STRADB,GH1,ADCY7,MAP3K4,UCN,PRKAR1A,DIRAS1,IRS1,ADCY5,PPP1R9A,FZD10,TGFBR2,CD40,EZH2,MAPKAPK5,TGFA,CALM1,RAF1,GPRC5B,FGFR1,PRKCZ,TNFRSF10B,ERBB4,ADCY8,ADCY9,DBNL,DUSP19,TNF,TEK,DSTYK,PIK3R5,CDKN1B,PARK7,MAPK1,ADCY4,CDK1,VEGFA,PKN1,P2RX7,SOD1,ZNF622,CCDC88A,GADD45A,EPHA4,WNT11,MAPK8IP3,MAGED1,MALT1,ADORA2B,PLCG1,CLSPN,CCNL2,ZP3,MDFI,HMGB1,GRM4,GAB1,DUSP7,MAP4K2,CARD10,VAPB,PDE6H,MRE11A,MARCKS,EGF,PROX1,SLC27A1,NTRK3,TLR4,TGFB3
GO:0006470	protein dephosphorylation	GO_PROTEIN_DEPHOSPHORYLATION	0.213767044067189	1.02408624392847	0.39495085566033	0.769578340229638	173	PTPRM,MTMR1,PTPRB,SSH2,EYA4,PPM1L,PPP2R3A,DAPP1,EYA1,MTMR4,BTRC,PTEN,PTPN21,PP2D1,PTPRK,PTPRN,DUSP27,PPTC7,PPP5C,PPP1R3B,CAMK2G,PPP3R1,RPRD1A,PDP1,DUSP19,DUSP21,PTPRG,PPP1R12A,PTPN7,PPM1N,CDC25C,DLGAP5,DUSP3,SSH1,PPP1CB,PPP1R3E,DUSP7,PPEF1,EPM2A,MTMR14,DUSP28,CTDSP2,PPM1M,DUSP4,RPRD1B,MYH8,DUSP26,MTMR2,PPP1R3C,CTDNEP1,DUSP10,PPM1B,STYXL1,PTPN4,PPP2CB
GO:1901565	organonitrogen compound catabolic process	GO_ORGANONITROGEN_COMPOUND_CATABOLIC_PROCESS	-0.189161930894515	-1.01610090483198	0.395077650599172	0.769578340229638	308	SMPDL3B,CHI3L1,CHDH,HDC,SMPD3,SHMT1,ACADL,AOX1,LIPC,GSTZ1,AGRN,MPG,NUDT18,DPYS,ALDH1L1,DUT,GPT2,GPC5,FMOD,LRTOMT,SDC1,ANPEP,CARNS1,SMPDL3A,TAT,SGPL1,CAT,HPSE,TDH,APOBEC3F,PDE11A,SLC6A3,IDUA,SMUG1,SAT1,NEIL2,UROC1,AGXT2,SGSH,BCAT1,NEU1,AMDHD1,GGT1,NT5M,SMOX,PGLYRP1,AGXT,GDA,NEU2,FTCD,HNMT,DCN,DDAH2,ALDH1L2,HSD17B10,OAT,FAH
GO:0021536	diencephalon development	GO_DIENCEPHALON_DEVELOPMENT	-0.236822024949793	-1.02735577330004	0.395772983244884	0.770166607005272	74	HAP1,SOX3,KDM1A,BMP4,WNT5A,BMP2,DUOX2,GBX2,SEMA3A,POU3F2,OTX1
GO:0034123	positive regulation of toll like receptor signaling pathway	GO_POSITIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	0.346014812829059	1.04392379427914	0.39593738975435	0.770166607005272	18	RSAD2,LBP,PELI1,CYBA,HMGB1,FLOT1
GO:0045017	glycerolipid biosynthetic process	GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS	0.20971023995624	1.02250358298747	0.396066071516972	0.770166607005272	198	PIK3C2B,CHAT,PIK3R1,MTMR1,LPIN1,DDHD2,MOGAT1,PCYT1A,TAZ,CHPT1,PLD1,LCAT,PLA2G5,INPP5J,PIP5K1B,ARF1,INPPL1,PLCE1,LPCAT4,AGPAT3,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,INPP5D,PIK3C3,PIP4K2C,IRS1,PIKFYVE,PI4K2A,GPAA1,PIP4K2B,FGFR1,AGPAT1,CDS2,PCYT1B,PIK3R5,PIK3C2G,MPPE1,PLD6,PIGM,LCLAT1,PIP5K1C,GAB1,FGF6,VAC14,FGF8,MTMR14,SLC27A1,SACM1L,INPP5F,CHKA,TAMM41,DPM2,PLA2G4D,PIGS,MTMR2,PCYT2,PIK3R6,CDIPT,PIK3R2,PIK3CB
GO:1904837	beta catenin tcf complex assembly	GO_BETA_CATENIN_TCF_COMPLEX_ASSEMBLY	-0.281167089704887	-1.03058747990544	0.396504241993515	0.770573486460838	34	PYGO1,HIST1H4C,LEO1,MEN1,CTNNB1,HIST1H4D,HIST1H4E,MYC,PYGO2
GO:0009261	ribonucleotide catabolic process	GO_RIBONUCLEOTIDE_CATABOLIC_PROCESS	0.309640789660452	1.03931310266669	0.397157665329744	0.771397981246346	27	PDE5A,PDE8B,ENTPD4,PDE4C,PDE2A
GO:0007257	activation of jun kinase activity	GO_ACTIVATION_OF_JUN_KINASE_ACTIVITY	-0.285508265506728	-1.03104007817846	0.397995165332328	0.772440103857055	32	TNFSF11,CCL19,WNT5A,MDFIC,RIPK1,MAP3K11,FCER1A,MAP3K2,AXIN1,MAP3K5,MAP3K9,MAP4K5
GO:0031098	stress activated protein kinase signaling cascade	GO_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE	-0.225272890313257	-1.02360047414128	0.398359139733953	0.772440103857055	96	MAPK8IP1,TNFSF11,CCL19,MAPK10,IRAK4,WNT5A,MAP2K4,MDFIC,MAP3K8,IRAK1,NPHS1,RIPK2,RIPK1,CHUK,UBA52,IKBKG,MAP3K11,NOD1,CUL1,FCER1A,MAP3K2,PTGER4,UBB,TRIB1,AXIN1
GO:0002756	myd88 independent toll like receptor signaling pathway	GO_MYD88_INDEPENDENT_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	-0.295948707121241	-1.03398038035522	0.398393538848556	0.772440103857055	28	LY96,RIPK1,CHUK,UBA52,IRF7,IKBKG,UBB,IKBKE
GO:0002052	positive regulation of neuroblast proliferation	GO_POSITIVE_REGULATION_OF_NEUROBLAST_PROLIFERATION	0.33509973409586	1.0401847659877	0.398612139156181	0.772440103857055	20	DRD2,SMARCD3,SHH,CX3CL1,VEGFA,PAX6
GO:0044321	response to leptin	GO_RESPONSE_TO_LEPTIN	-0.333655287325521	-1.03615110194649	0.398894788167732	0.772543070755228	18	STAT3,NR4A3,STAR,LEP,CCNA2,EDN1,SIRT1
GO:1900087	positive regulation of g1 s transition of mitotic cell cycle	GO_POSITIVE_REGULATION_OF_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE	0.318258279515638	1.03705350571134	0.400231592103812	0.774686336412554	24	CUL4A,DDX3X,CREBBP,KCNA5,ANKRD17,RDX,CYP1A1,PPP1R1C
GO:0051155	positive regulation of striated muscle cell differentiation	GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION	0.264303368490463	1.03115642618844	0.400537105004028	0.774689378167576	52	EHD1,PIN1,BMP10,AKAP6,CAV3,DDX39B,SMYD1,SHH,EP300,MTOR,IL4,SCGB3A1,TRIM32,MYLK3,CXCL9,GDF15,PROX1,FLOT1,MEF2C
GO:0032674	regulation of interleukin 5 production	GO_REGULATION_OF_INTERLEUKIN_5_PRODUCTION	-0.333166096577092	-1.03463194264555	0.400693466247697	0.774689378167576	18	RARA,TNFRSF21,GATA3
GO:0034587	pirna metabolic process	GO_PIRNA_METABOLIC_PROCESS	-0.352324294496181	-1.03793582589124	0.401077852087527	0.774987399613442	15	TDRD1,TDRD12,MOV10L1
GO:0008593	regulation of notch signaling pathway	GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY	-0.245746324876189	-1.02584701108327	0.402097340462149	0.776170839913472	61	BEND6,DLX1,GDPD5,POGLUT1,ITGB1BP1,CHAC1,STAT3,IL6ST,TSPAN15,NOV,TSPAN5
GO:2000401	regulation of lymphocyte migration	GO_REGULATION_OF_LYMPHOCYTE_MIGRATION	-0.28020313805543	-1.02705421965721	0.402189845866832	0.776170839913472	34	CCL3,WNT5A,TNFSF14,PYCARD,CCL21,RIPK3,MSN,CCL4
GO:0051953	negative regulation of amine transport	GO_NEGATIVE_REGULATION_OF_AMINE_TRANSPORT	0.317712137441439	1.03527388648658	0.402382090210639	0.776170839913472	24	P2RY1,DRD2,ADRA2C,GCK,AGTR2,GABBR1,NPY5R
GO:0006909	phagocytosis	GO_PHAGOCYTOSIS	-0.20698238005123	-1.01887252863788	0.402914670175526	0.776753023946632	158	TYRO3,PIP5K1A,ANXA3,RARA,COLEC12,FCGR2A,ALOX15,SCFD1,PDIA6,ARPC5,ANXA1,ACTG1,ACTR3,BAIAP2,TULP1,FCN3,IGHG4,ABCA7,IGHG2,IGHG1,ABCA1,NR1H3,MBL2,IGHD,CORO1C,THBS1,IGKC,WIPF2,HSP90AA1,LRP1,IGLL1,IGLC1,CDC42,CEBPE,ELANE
GO:0070228	regulation of lymphocyte apoptotic process	GO_REGULATION_OF_LYMPHOCYTE_APOPTOTIC_PROCESS	-0.253677500348655	-1.02413855997096	0.40344757288151	0.777064937874759	52	NOC2L,BBC3,BMP4,WNT5A,SLC39A10,HIF1A,RIPK3,LGALS16,RAG1,FAS,PRELID1,AURKB,BAX,MIF,GPAM
GO:0031532	actin cytoskeleton reorganization	GO_ACTIN_CYTOSKELETON_REORGANIZATION	-0.253668100027434	-1.02410060929963	0.403538179264729	0.777064937874759	52	EZR,PIP5K1A,FGF7,PTK7,ANXA1,PARVA,BRSK2,WHAMM,ANTXR1,PARVG,S100A9
NA	regulation of tumor necrosis factor biosynthetic process	GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS	0.34953903521896	1.03837968959593	0.403808957000446	0.777141766302746	17	MAPKAPK2,SPN,GHSR,LBP,CCR2,HSPB1,LILRB1,TLR4
GO:0002285	lymphocyte activation involved in immune response	GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.234729803283362	1.02421364553002	0.404466544232302	0.77763718108035	94	RC3H2,ATP7A,UNC13D,ITFG2,LFNG,TSC1,MFNG,KLRF2,VAMP2,HSPD1,ERCC1,ADA,IL18R1,AICDA,IL4,EXOSC3,ITGAL,HMGB1,LILRB1,RNF168,IFNA21,TLR4
GO:0032703	negative regulation of interleukin 2 production	GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION	-0.344127482332209	-1.03401648883354	0.404528432582202	0.77763718108035	16	EZR,GATA3,CD34,IL20RB,CD276,TRIM27,HDAC7
GO:0050909	sensory perception of taste	GO_SENSORY_PERCEPTION_OF_TASTE	-0.246769221164888	-1.02320543240696	0.405786180755355	0.779305381685897	59	SCNN1A,CST2,AZGP1,PKD1L3,TAS2R41,CST1,TAS2R16,WNT10B,GNAT1,CALHM1,SCNN1G,PIGR,ITPR3,SCNN1B
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	GO_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS	-0.22542319774922	-1.0206294905114	0.406111058556428	0.779305381685897	94	VASN,CDKN2B,ITGA3,SNW1,TGFBR1,NPNT,HTRA1,SNX25,SOX11,SKIL,CIDEA,MEN1,UBA52,DAB2,SMAD2,SMURF2,IL17F,ONECUT1,THBS1,PDPK1,ZNF703
GO:0061097	regulation of protein tyrosine kinase activity	GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY	0.257301843093036	1.02628955944893	0.40628281569814	0.779305381685897	58	AGT,FBXW7,PDGFB,DVL2,APP,UNC119,ADRA2C,ZGPAT,TGFA,GPRC5B,RAP2C,SOCS4,SH3BP5L,HYAL2,EGF,IBTK,HSPH1,EREG,ACE
GO:0038179	neurotrophin signaling pathway	GO_NEUROTROPHIN_SIGNALING_PATHWAY	0.320503623783169	1.03338338039023	0.406322324675802	0.779305381685897	23	ZFYVE27,RAPGEF1,RAPGEF2,RAF1,SORT1,AKT1S1,NTRK3,DDIT4
GO:0008214	protein dealkylation	GO_PROTEIN_DEALKYLATION	0.310887765578749	1.03376832665905	0.406608115293643	0.779409405511619	26	PHF2,KDM3B,KDM2B,KDM5A,PPME1,HSF4,JMJD6,KDM5C,UBE2B
GO:0000288	nuclear transcribed mrna catabolic process deadenylation dependent decay	GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY	0.265462858478176	1.02685382743316	0.406861513051596	0.779451253802887	50	DCP2,EXOSC4,EXOSC7,LSM5,PAN2,CNOT6L,CNOT4,EDC3,LSM4,EXOSC3,DCP1A,CNOT8,PATL1,LSM6,EIF4G1,CNOT1,LSM1,MLH1,ZFP36L2,RC3H1
GO:2000379	positive regulation of reactive oxygen species metabolic process	GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS	-0.232700478814595	-1.02161030654202	0.407974102796991	0.781138128563522	79	ASS1,ZNF205,TSPO,SNCA,OPRM1,AGTR1,KLF4,AKR1C3,RIPK1,CDKN1A,EGFR,F2,RIPK3,AGXT2,LEP,DUOXA1,DDAH2,THBS1,HSP90AA1,PKD2,EDN1,NFE2L2
GO:0061383	trabecula morphogenesis	GO_TRABECULA_MORPHOGENESIS	0.285823133135444	1.02804492674861	0.408562358276644	0.781819725957467	36	UBE4B,BMP10,NACA,CAV3,EGLN1,DLL4,S1PR1,NKX2-5,TEK,FHL2,HEY2,MED1,SRF,TGFBR3
GO:0007569	cell aging	GO_CELL_AGING	0.255159897670268	1.02433736753531	0.408909976187938	0.782040329459431	60	TBX2,NPM1,HMGA1,KAT6A,ERCC1,DNAJA3,MAPKAPK5,MTOR,ZMIZ1,ULK3,CDK1,ENG,SOD1,LIMS1,OPA1,ROMO1,TBX3,NOX4,SRF,BRCA2,WRN,NSMCE2
GO:0042398	cellular modified amino acid biosynthetic process	GO_CELLULAR_MODIFIED_AMINO_ACID_BIOSYNTHETIC_PROCESS	-0.260234956663092	-1.02331377101718	0.410261034218475	0.784178671879266	46	CHDH,CHAC2,GART,MTHFD1L,CHAC1,CPS1,PADI4,DHFR,GGT1,GGCT
GO:0008209	androgen metabolic process	GO_ANDROGEN_METABOLIC_PROCESS	-0.29355384153963	-1.02561324116728	0.410684731999029	0.784304636919948	28	HSD17B6,SRD5A3,UGT2B7,SGPL1,AKR1C3,STAR
GO:0031345	negative regulation of cell projection organization	GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION	-0.211336322843703	-1.01629079090786	0.41079295154185	0.784304636919948	135	SEMA3F,SEMA3C,TBX6,ITGA3,NLGN1,EFEMP1,WNT5A,ULK2,SPOCK1,LPAR1,KATNA1,RTN4,SEMA3A,SEMA3B,EVL,CCL21,YWHAH,MAG,SEMA3D,CERS2,CDK5,DPYSL3,FGF13,SEZ6,SEMA3E,SEMA4B,LRP1,RHOA,SEMA4A,FSTL4
GO:0060078	regulation of postsynaptic membrane potential	GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL	0.260190248726044	1.02280236176993	0.411963277845253	0.786093193439411	54	NLGN3,SCN7A,SCN1A,DRD4,ADRB2,SCN5A,LRRK2,GRIN2C,RAB3GAP1,PPP1R9A,CX3CL1,GRIK5
GO:0007431	salivary gland development	GO_SALIVARY_GLAND_DEVELOPMENT	-0.285151511081442	-1.02139316179833	0.412568669147617	0.786802345807862	31	SEMA3C,FGF7,FGFR2,SEMA3A,XBP1,EDAR,EGFR
GO:0001649	osteoblast differentiation	GO_OSTEOBLAST_DIFFERENTIATION	-0.215633274453963	-1.01486863279642	0.413176117379304	0.787514615571198	118	CCL3,UFL1,BMP4,BMP2,ALPL,SND1,NR1I3,CYR61,CREB3L1,GDF10,RPS11,MRC2,MEN1,FIGNL1,CAT,MSX2,PTHLH,RSPO2,CBFB,CLEC5A,FGF9,RSL1D1,FASN,EPHA2,WWOX,TMSB4X,TPM4
GO:0045604	regulation of epidermal cell differentiation	GO_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION	-0.264724075152024	-1.02000661307354	0.413591318774943	0.787859863608635	42	SFN,BMP4,AQP3,HOXA7,GRHL2,ERRFI1,MSX2,IL20,KEAP1
GO:0006638	neutral lipid metabolic process	GO_NEUTRAL_LIPID_METABOLIC_PROCESS	0.239332223852166	1.01947485892504	0.413937221299292	0.788072786704421	82	LPIN1,MOGAT1,SLC27A5,CYP2E1,APOC3,FABP9,PCSK9,CEL,ABHD2,FABP7,PLCE1,LPCAT4,AGPAT3,CAV3,ABHD6,DGAT2L6,MGLL,AGPAT1,INSIG1,LIPF,FABP3,CETP,LCLAT1
GO:0006661	phosphatidylinositol biosynthetic process	GO_PHOSPHATIDYLINOSITOL_BIOSYNTHETIC_PROCESS	0.224999323132584	1.01813735905704	0.414627904596172	0.788941507558346	117	PIK3C2B,PIK3R1,MTMR1,INPP5J,PIP5K1B,ARF1,INPPL1,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,INPP5D,PIK3C3,PIP4K2C,IRS1,PIKFYVE,PI4K2A,GPAA1,PIP4K2B,FGFR1,PIK3R5,PIK3C2G,MPPE1,PIGM,PIP5K1C,GAB1,FGF6,VAC14,FGF8,MTMR14,SLC27A1,SACM1L,INPP5F,DPM2,PIGS,MTMR2,PIK3R6,CDIPT,PIK3R2,PIK3CB,GRB2,SYNJ1,PIK3CG,PIGO,PIGG,PIK3C2A
GO:0035239	tube morphogenesis	GO_TUBE_MORPHOGENESIS	-0.187367283533646	-1.00938978366648	0.415978407557355	0.790919120120188	316	WNT6,PAX8,OSR1,RARA,SPINT1,WT1,RDH10,IFT57,AREG,BMP4,WNT5A,SFRP2,BMP2,MET,T,NPNT,KRAS,GATA3,PTK7,GRHL2,FGFR2,BBS7,TMED2,FOXF1,FOXA1,ITGB1BP1,SOX11,MTHFD1L,GBX2,ACVR1,PLXNB2,COBL,EDAR,CTNNB1,DLG5,NR4A3,CSF1,EGFR,MSX2,HIF1A,ST14,FZD3,STK3,SMAD2,ZIC3,RSPO2,IRX1,NKX2-3,GDNF,IFT52,TIMELESS,STX2,SEMA3E,ARL13B,BAX,EPHA2,ACVR2B,RALA,WNT9B,TULP3,PPP1CA,PKD2,RHOA,SALL4,NODAL,LMO4,GNA13,MYC,EDN1,STIL
GO:1903201	regulation of oxidative stress induced cell death	GO_REGULATION_OF_OXIDATIVE_STRESS_INDUCED_CELL_DEATH	0.274432169492923	1.02225387463587	0.416137184115523	0.790919120120188	42	TRAP1,FBXW7,LRRK2,PINK1,SOD2,PARK7,HDAC6,SOD1,HSPB1,SFPQ,NME5,ENDOG,VNN1,HSPH1
GO:0048736	appendage development	GO_APPENDAGE_DEVELOPMENT	-0.205933957118899	-1.01283002377546	0.41677822400714	0.791690463887151	157	C5orf42,GDF5,SEMA3C,OSR1,TRAF3IP1,RARA,CYP26B1,RDH10,BMP4,WNT5A,SFRP2,WNT9A,GRHL2,FGFR2,BBS7,SOX11,HOXC10,COMP,CTNNB1,BMPR1B,PLXNA2,WDR19,MSX2,FGF4
GO:0045005	dna dependent dna replication maintenance of fidelity	GO_DNA_DEPENDENT_DNA_REPLICATION_MAINTENANCE_OF_FIDELITY	0.340685590400447	1.02784557481579	0.417345934604601	0.791812958856799	18	FBXO18,ZRANB3,MMS22L,ATRX,TIPIN,BRCA2,WRN,SETMAR,SMARCAL1,RAD51
GO:1905037	autophagosome organization	GO_AUTOPHAGOSOME_ORGANIZATION	0.278855095336168	1.0218050578101	0.417473973395026	0.791812958856799	39	ATG14,TP53INP2,MFN2,ATG16L1,PIK3C3,WIPI2,ATG9A,MAP1LC3A,WDR45,ATG16L2,MAP1LC3B,PACS2,ATG3,ATG4D
GO:0046839	phospholipid dephosphorylation	GO_PHOSPHOLIPID_DEPHOSPHORYLATION	0.317837572328849	1.0247873675538	0.41835347709489	0.791812958856799	23	MTMR1,INPP5J,INPPL1,PTEN,INPP5D,INPP5A,SACM1L,INPP5F,MTMR2,SYNJ1
GO:0009247	glycolipid biosynthetic process	GO_GLYCOLIPID_BIOSYNTHETIC_PROCESS	-0.247016486113495	-1.01664941297078	0.418384997041285	0.791812958856799	57	GAL3ST1,PIGV,PIGW,B3GNT5,PIGX,PLAUR,GAL3ST2,GAL3ST4,PIGU,ST3GAL5,PIGZ,PIGF,PIGQ,PIGK,UGT8
GO:0010744	positive regulation of macrophage derived foam cell differentiation	GO_POSITIVE_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION	-0.347581637265979	-1.02396411310831	0.418457675908491	0.791812958856799	15	PLA2G2A,AGTR1,CSF1,LPL
GO:0090330	regulation of platelet aggregation	GO_REGULATION_OF_PLATELET_AGGREGATION	-0.340642655345524	-1.02354546065368	0.418901660280971	0.791812958856799	16	PRKCA,C1QTNF1,ADAMTS18,ABAT,ZAP70
NA	nuclear import	GO_NUCLEAR_IMPORT	0.223393320020474	1.01554369700301	0.419142307495872	0.791812958856799	120	OR1D2,AGT,ADAR,PIK3R1,PRICKLE1,RANBP6,TSC2,NUP85,RERE,RAE1,POLA2,JAK2,NUP188,TNF,SMN1,IPO8,MAPK1,CBLB,KPNA4,KPNA3,TPR,BCL6,KPNA6,NFKBIA,DDX20,EGF,TGFB3,TNPO3,SPTBN1,MT3,JAK3,NUP214,SIX2,RBM22,NCKIPSD,KPNB1,MCM3AP,NUP35,IPO7,PDIA3,GEMIN2,MAPK3,NUP93,IPO13,DAG1,IPO9,GEMIN5,RANBP17,NUP133,TGFB1,PTTG1IP,TMCO6,NOP58,SNRPD3,SIX3
GO:0003230	cardiac atrium development	GO_CARDIAC_ATRIUM_DEVELOPMENT	0.302310162840746	1.02435700081336	0.41934717015635	0.791812958856799	28	ANK2,BMP10,DLL4,DAND5,GJA5,TBX5,TBX20,NKX2-5,HEY2,PROX1
GO:0051353	positive regulation of oxidoreductase activity	GO_POSITIVE_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY	0.27077968439256	1.01932633045799	0.419360648356596	0.791812958856799	44	AGT,ATP7A,CALM3,ESR1,FTMT,CYP27B1,AGTR2,CALM1,TNF,PARK7,CCS,RFK,FXN
GO:1903828	negative regulation of cellular protein localization	GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION	0.221728443468898	1.01461492727261	0.419579826228618	0.791812958856799	125	GPM6B,FLCN,PYDC2,TP53INP2,LRRK2,AKAP1,RANGAP1,NEDD4L,SP100,SUFU,PKIA,GSK3B,CAV3,SIAH3,SIRT4,CABP1,PDE2A,DERL3,MTOR,GBP1,YOD1,EMD,PARK7,PPFIA1,BAG4,AP2M1,FAF1,MDFI,CD36,LITAF,NFKBIA,COMMD1,FAM89B
NA	misfolded or incompletely synthesized protein catabolic process	GO_MISFOLDED_OR_INCOMPLETELY_SYNTHESIZED_PROTEIN_CATABOLIC_PROCESS	0.357421615580929	1.02703938753265	0.419580289596461	0.791812958856799	15	ANKZF1,LONP2,LONP1,HDAC6,VCP,SDF2L1
GO:0007030	golgi organization	GO_GOLGI_ORGANIZATION	0.241018716913827	1.01549798865257	0.419665572965101	0.791812958856799	77	KIFC3,RAB30,VCPIP1,CLASP1,GAK,LRRK2,GOLGA2,OBSL1,GORASP1,VTI1A,ARL1,PLEKHM2,CDK1,ARFGEF1,ARHGAP21,COG2,NPLOC4,CSNK1A1,ATP8B1,HTT,GBF1,DYM,BCAS3
GO:1901623	regulation of lymphocyte chemotaxis	GO_REGULATION_OF_LYMPHOCYTE_CHEMOTAXIS	-0.328363663527813	-1.01971820836632	0.420132192003467	0.792249276349396	18	CCL3,WNT5A,TNFSF14
GO:0003014	renal system process	GO_RENAL_SYSTEM_PROCESS	0.232780812676089	1.01570947287254	0.420631345507467	0.7927464216003	94	AGT,GNAS,PRKACA,OPRL1,PDGFB,SERPINF2,HSD11B2,ADRB2,DRD2,GJA1,ADCY7,PRKAR1A,ADCY5,AGTR2,SLC4A5,ADCY8,GJA5,ADCY9,XPNPEP3,KCNMA1,MCAM,ADCY4,PKN1,CYBA
GO:1901342	regulation of vasculature development	GO_REGULATION_OF_VASCULATURE_DEVELOPMENT	-0.19676439001037	-1.00974642265422	0.421101175988317	0.793187777491144	212	CHI3L1,CMA1,PRKCA,PTGIS,C3,SULF1,ANXA3,KDR,NPR1,WT1,AQP1,PRKD1,BMP4,WNT5A,SFRP2,ITGB1BP1,SRPX2,KLF4,CTNNB1,FGF18,ANGPTL3,KLK3,ANGPT4,TNMD,HIF1A,ANGPTL4,LEP,C5AR1,SPARC,RAPGEF3,IL17F,HGF,C5,CD34,DCN,SEMA3E,THBS1,EPHA2,THBS2,VASH2,RHOA,SEMA4A,NODAL,PDGFD,PTGER4,THBS4,F3,SIRT1,GTF2I,PF4,SERPINF1,FGF2,PDCD10,ISL1,ENPP2,MAP2K5,GATA6,RAP1A,FGF16,CYP1B1
GO:0036297	interstrand cross link repair	GO_INTERSTRAND_CROSS_LINK_REPAIR	-0.279267448379027	-1.01629490462675	0.421546030761048	0.79358162166761	33	RPA3,FANCF,UBA52,RPA2,DCLRE1B,RNF8,UBB,USP1,FANCL,FANCE,XPA,FANCG,MUS81,FANCM,RPS27A,FANCB
GO:0006825	copper ion transport	GO_COPPER_ION_TRANSPORT	-0.32781569363109	-1.01801651313207	0.422169249106079	0.794310616261074	18	STEAP3,STEAP1,CP,SLC31A1,ATP7B,STEAP1B
GO:0045445	myoblast differentiation	GO_MYOBLAST_DIFFERENTIATION	-0.274671877122718	-1.01416105513604	0.422541785206259	0.79451763288543	35	DTYMK,T,SDC1,MAPK12,WNT10B,CTNNB1
GO:0007160	cell matrix adhesion	GO_CELL_MATRIX_ADHESION	-0.2182749504483	-1.01221055895251	0.422751360813371	0.79451763288543	108	VTN,MSLN,ITGA3,PIP5K1A,ITGB8,CTGF,NPNT,THBS3,ADAM15,ITGB1BP1,TNXB,CTNNB1,ANGPTL3,CCL21,HPSE,WHAMM,RHOD,PARVG,CDK5
GO:0099601	regulation of neurotransmitter receptor activity	GO_REGULATION_OF_NEUROTRANSMITTER_RECEPTOR_ACTIVITY	0.298501322206804	1.02019925567153	0.42300180699801	0.794533209218534	29	SHANK3,NLGN3,NRXN1,DLG4,SHANK1,RASGRF1
GO:0051954	positive regulation of amine transport	GO_POSITIVE_REGULATION_OF_AMINE_TRANSPORT	0.293264517739345	1.01885287392583	0.423238178570127	0.794533209218534	31	DRD4,DRD2,OPRK1,SLC6A1,PINK1,STX1A,RAB3GAP1,GABBR1,P2RX7,SLC38A3,DPYSL2,TMEM27,OXT,PCP4,CXCL12
GO:0031109	microtubule polymerization or depolymerization	GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION	-0.267803454987374	-1.01403952662678	0.423467788870484	0.794533209218534	39	KIF2C,KIF18A,MAP7D3,STMN3,SGK1,FBXO5,HDGFRP3,FGF13
GO:0044242	cellular lipid catabolic process	GO_CELLULAR_LIPID_CATABOLIC_PROCESS	0.216776551535825	1.01179294828643	0.425041741858229	0.796077199614558	144	SLC25A17,DECR1,IVD,PPARD,LPIN1,ACOX3,ACAD9,ACADM,MMAA,ACAD10,APOC3,PLA2G4C,FABP9,CEL,ABHD2,FABP7,ABHD6,NEU3,PLA2G15,MGLL,SMPD4,HADH,LIPG,ECI2,ETFA,PEX7,ACOT8,HADHB,PLA2G4E,PCCB,FABP3,ECHS1,PLCG1,GCDH,ACADVL,PCCA,NAPEPLD,NAGA,HADHA,GPCPD1,PNPLA6,INPP5F,SCP2,PLA2G4D,APOA5,MCEE,MT3,FABP12,MUT,ACADSB,SMPD1,PNPLA2,SIRT2,CRABP1
GO:0051099	positive regulation of binding	GO_POSITIVE_REGULATION_OF_BINDING	0.22213238511071	1.01249425920863	0.42526645022013	0.796077199614558	122	PLCL1,NRP1,HMBOX1,EPB41,TIAM1,LRRK2,CALM3,LFNG,EBF2,HAND2,MFNG,HIPK2,ADD1,GSK3B,RAPGEF2,JAK2,CSF3,MED25,KAT2A,HIST1H2BA,CALM1,EP300,ACD,TMEM173,SPAG8,PARK7
GO:0051900	regulation of mitochondrial depolarization	GO_REGULATION_OF_MITOCHONDRIAL_DEPOLARIZATION	-0.345839824319602	-1.01883278924763	0.425340345864987	0.796077199614558	15	KDR,TSPO,DCN,IFI6,BCL2,GCLM,NGFR
GO:0002475	antigen processing and presentation via mhc class ib	GO_ANTIGEN_PROCESSING_AND_PRESENTATION_VIA_MHC_CLASS_IB	0.355828135674082	1.02246057484693	0.425361066190821	0.796077199614558	15	CD1E,TAP2,CD1B,ABCB4,HLA-E,TAP1
GO:0034446	substrate adhesion dependent cell spreading	GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING	0.280674017075804	1.01661840263457	0.425638611800062	0.796077199614558	37	ITGA8,LAMC1,PEAK1,ITGB3,EPHA1
GO:1901739	regulation of myoblast fusion	GO_REGULATION_OF_MYOBLAST_FUSION	0.33380604495961	1.02148565576059	0.425709732414202	0.796077199614558	19	EHD1,CFLAR,IL4,SCGB3A1,CXCL9,GDF15,FLOT1
GO:0016574	histone ubiquitination	GO_HISTONE_UBIQUITINATION	0.28669866805076	1.01779096961284	0.42594950523865	0.796083306292779	34	UHRF1,RNF40,PAF1,KDM2B,UBE2N,HUWE1,BCOR,RNF168,UBE2B,UBR2
GO:0044380	protein localization to cytoskeleton	GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON	0.30344454628104	1.01851533587829	0.4268813068879	0.796682296297566	27	SPAG5,KLHL21,C2CD3,GSK3B,FAM83D
GO:0010288	response to lead ion	GO_RESPONSE_TO_LEAD_ION	-0.316945200457045	-1.01281822920035	0.427418302075628	0.796682296297566	20	SLC34A1,ANXA5,CAT,STAR,SPARC,HMBS
GO:0050777	negative regulation of immune response	GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE	-0.217983293969942	-1.00958848484162	0.427477078495679	0.796682296297566	107	CD55,TYRO3,APOA2,C4BPA,PTPN2,ANGPT1,ALOX15,FOXF1,SERPING1,RPS19,ANXA1,C4BPB,NLRP6,IRAK3,MASP1,LILRB2,PPARG,NR1H3,PGLYRP1,ADCYAP1,IL2RA,FCRLB,IFI16,IL20RB,CUEDC2,IL4R,CD46,IL10,TRIM27,PGLYRP2,DUSP22
GO:0048259	regulation of receptor mediated endocytosis	GO_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS	-0.232560430432973	-1.01126402190146	0.427673393644166	0.796682296297566	75	VTN,RSPO1,APOC1,CCL19,NLGN1,SNAP91,ANGPT1,PROM2,ANXA2,TOR1A,CCL21
GO:0015748	organophosphate ester transport	GO_ORGANOPHOSPHATE_ESTER_TRANSPORT	-0.230294497738004	-1.01104747883444	0.427676471273202	0.796682296297566	79	APOA2,APOC1,PITPNM3,MFSD2A,SLC25A6,ATP8B3,SLC35A3,ATP10B,ABCA7,CALHM1,TNFAIP8L3,ABCA1,SLC25A19,ATP11C,PRELID1,ATP9A,KCNN4,ABCG1,TRIAP1,SLC37A1,PITPNM1,OSBPL8
GO:0050687	negative regulation of defense response to virus	GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS	-0.338269021615898	-1.01641328859276	0.427690109747386	0.796682296297566	16	TARBP2,TRAF3IP1,HTRA1
GO:0043550	regulation of lipid kinase activity	GO_REGULATION_OF_LIPID_KINASE_ACTIVITY	0.26550818495721	1.01350779191872	0.428358262620452	0.797485570785642	47	PIK3R1,PDGFB,ATG14,EEF1A2,FLT1,PIK3R3,IRS1,ERBB4,TEK,PIK3R5,PIK3IP1
GO:0048240	sperm capacitation	GO_SPERM_CAPACITATION	0.348679020550735	1.01881744239651	0.429328129356008	0.798537856367216	16	PRKACA,DLD,ABHD2,ACRBP,SLC26A3,CATSPER4
GO:0003206	cardiac chamber morphogenesis	GO_CARDIAC_CHAMBER_MORPHOGENESIS	-0.222108671820073	-1.00922282068548	0.429397956038224	0.798537856367216	96	SEMA3C,RBP4,RARA,WNT5A,SFRP2,GATA3,GRHL2,FGFR2,FOXF1,NPY2R,CYR61,SOX11,ACVR1,PARVA,MSX2,HIF1A,TPM1,WHSC1
GO:1901185	negative regulation of erbb signaling pathway	GO_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY	-0.26512717536444	-1.00959801625383	0.430123180291153	0.799262438947799	40	GPRC5A,PTPN2,STAM2,ERRFI1,EGFR,UBA52,RNF126,CDC42,UBB,PSEN1,SH3GL2,HGS,SNX6,SPRY1,RPS27A,ZFYVE28
GO:0034341	response to interferon gamma	GO_RESPONSE_TO_INTERFERON_GAMMA	0.218866512642433	1.00894990844145	0.430262489415749	0.799262438947799	132	CCL1,IRF2,CAMK2A,CALCOCO2,IRF6,XCL1,TRIM26,CCL24,SP100,OAS2,JAK2,CYP27B1,CIITA,HLA-B,DNAJA3,CX3CL1,CAMK2G,MEFV,OASL,HLA-H,OAS3,IRF1,OAS1,GBP5,DAPK3,GBP1,CAMK2B,CCL16,GBP2,TRIM31,PTAFR,NCAM1,CCL23
GO:0060561	apoptotic process involved in morphogenesis	GO_APOPTOTIC_PROCESS_INVOLVED_IN_MORPHOGENESIS	0.354157822095206	1.01766098310358	0.431569360025279	0.801160542381807	15	LRP5,HAND2,NKX2-5,SPI1,BAK1
NA	protein targeting to plasma membrane	GO_PROTEIN_TARGETING_TO_PLASMA_MEMBRANE	-0.304972968720397	-1.01154155078612	0.431760316066725	0.801160542381807	23	PIP5K1A,PRKG2,TMED2,ANXA2,KCNB1,INPP5K,TESC,PALM,EHD3,GAS6
GO:0006817	phosphate ion transport	GO_PHOSPHATE_ION_TRANSPORT	0.336821470615986	1.01618755776744	0.432107246968825	0.801185674900578	18	SLC17A3,SLC25A3,SLC20A2,SLC17A1,IP6K2,SLC34A3
GO:0010035	response to inorganic substance	GO_RESPONSE_TO_INORGANIC_SUBSTANCE	-0.179997655758593	-1.00458468353817	0.432249906601144	0.801185674900578	449	KRT8,ASS1,ATP13A2,SLC34A1,C3,DTYMK,MT1M,KHK,CCL19,LIPC,ALDOB,KCNMB2,MT1E,AQP1,AREG,BMP4,WNT5A,HP,AQP3,TNFRSF11B,LDHA,ALOX15,GART,SDC1,ANXA5,MT2A,KCNH1,TSPO,CRIP1,TAT,PKLR,SNCA,CALR,ANXA1,TACR1,SLC18A1,KLF4,WNT10B,MT1A,CTNNB1,CAT,SLC30A2,CP,CEBPA,AKR1C3,NR4A3,MT1F,SLC6A3,STAR,HIF1A,CPS1,EIF2AK3,ZACN,FBP1,FABP4,CASP3,CCNB1,SLC18A2,RPS3,ADCY10,MT1G,KEAP1,SPARC,NQO1,CCNA2,KRT14,RYR3,ITPR3,FAS,HMBS,CDH1,CPNE6,SLC30A8,IL1R1,KCNA1,CYP1A2,FABP1,ADPRHL2,THBS1,BAX,KLF6,ASPH,ADAM9,CYB5A,ATP7B,PKD2,ABAT,MDM2,CPNE3,SEC31A,EDN1,PDGFD,JUNB,NFE2L2,GUCA1A,GPAM
GO:0019318	hexose metabolic process	GO_HEXOSE_METABOLIC_PROCESS	0.21587424059334	1.00849353507113	0.43264480229323	0.801476282068801	145	LRP5,BAD,PPARD,AKT2,DLAT,NPY1R,PGM5,PGAM2,PGAM1,FUT5,SLC25A11,INPPL1,PDHA1,PFKM,GCK,MDH2,MDH1,WDTC1,PFKFB4,GOT2,OAS1,PFKP,TNF,ALDOC,MPI,FUT4,PDHB,ALDOA,HK3,ENO2,GALK1,MAN2A2,SERPINA12,GOT1,CRTC2,FUCA2,MAN2C1,SLC25A12,FUCA1,SLC25A10,NISCH,GPI,PDK3,USF1,IGFBP5,ADPGK,ALDH1A1,PGK1,GALT
GO:0001776	leukocyte homeostasis	GO_LEUKOCYTE_HOMEOSTASIS	-0.244980899393451	-1.00827151853732	0.433337885201875	0.801536772777168	57	TNFSF14,SKIL,ANXA1,CACNA1F,HIF1A,RIPK3,HCAR2,CASP3,NKX2-3,RAG1,LAT,FAS,BAX,FLT3,IL2RA,SPNS2,RPS6,ABL1,BCL2,PDE4B,TNFRSF13C,TNFRSF17
GO:0032228	regulation of synaptic transmission gabaergic	GO_REGULATION_OF_SYNAPTIC_TRANSMISSION_GABAERGIC	-0.28913202873469	-1.01016438947137	0.433347308956904	0.801536772777168	28	HAP1,CNR1,NLGN1,KRAS,TACR1,CNR2,SYN3,HTR1B
GO:0045620	negative regulation of lymphocyte differentiation	GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	0.279291732355038	1.0116116830976	0.433405145102015	0.801536772777168	37	CTLA4,HLX,ZC3H8,SHH,IRF1,DTX1,IL4,HMGB1,BCL6,FOXJ1,TNFSF4,JAK3,KIAA0922,NFKBID,FOXP3,CDKN2A,RC3H1
GO:0006281	dna repair	GO_DNA_REPAIR	0.190416977893807	1.00685499234412	0.433864233802381	0.801536772777168	408	SMARCB1,CUL4A,RPA4,UHRF1,HERC2,FBXO6,ZSWIM7,TRIP12,NPM1,EYA4,UNG,ZFYVE26,DMC1,RNF111,UBE2N,TAOK3,RAD23A,MCRS1,UBE2T,WDR33,EYA1,IGHMBP2,SMG1,HMGA1,FZR1,EXD2,LOC100133315,REV1,HUWE1,COPS6,RAD21L1,HIST1H4F,TREX2,FBXO18,ZRANB3,PSME4,UBR5,COPS7A,ERCC1,GTF2H3,SMC1A,LIG3,PPP5C,REV3L,EP300,POLG,COPS7B,POLD2,ERCC4,POLR2I,SETX,UBA7,INTS3,MTOR,MLH3,XAB2,MMS22L,RECQL5,RFC3,TOPBP1,CDK1,AQR,RAD51AP1,VCP,JMY,USP28,PRPF19,NFRKB,HMGN1,GTF2H5,PMS2P5,HUS1,GADD45A,WRNIP1,SFPQ,NPLOC4,ATRX,CLSPN,HMGB1,FTO,MUM1,SUMO2,ASCC1,SUMO1,PRKDC,RNF168,PIAS4,POLK,MRE11A,ASF1A,MTA1,UBE2B,UVRAG,POLR2C,MMS19,FAN1,UBE2I,NEIL3,EEPD1,KIN,CCDC155
GO:0033559	unsaturated fatty acid metabolic process	GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS	-0.2194142328552	-1.00634474687552	0.433868092691622	0.801536772777168	101	PDPN,PTGIS,SSTR4,CYP2C9,ALOX15,ALOX12B,TBXAS1,AKR1C3,DAGLA,DECR2,TNFRSF1A,PLA2G4F,HPGD,GGT1,PTGR1,CYP4F2,PTGS1,CYP1A2,MIF,DEGS1,EDN1,FCER1A
GO:0001906	cell killing	GO_CELL_KILLING	0.259024190656907	1.0105601765865	0.434589562259422	0.801889502045056	52	BAD,UNC13D,CRTAM,GZMB,KIR3DL1,KLRF2,VAMP2,CTSH,DCD,HAMP,CCR2,ULBP1,MICA
GO:0016486	peptide hormone processing	GO_PEPTIDE_HORMONE_PROCESSING	-0.288872651706062	-1.0092581825772	0.434759582496635	0.801889502045056	28	CMA1,SCG5,CPA3,PCSK1N,PCSK1,MME,POMC
GO:0019883	antigen processing and presentation of endogenous antigen	GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_ANTIGEN	0.347183361867263	1.01444722490483	0.434773719914506	0.801889502045056	16	TAP2,HLA-B,ABCB4,HLA-E,TAP1,HLA-A,ABCB9,CD74,B2M,ERAP2
GO:0010743	regulation of macrophage derived foam cell differentiation	GO_REGULATION_OF_MACROPHAGE_DERIVED_FOAM_CELL_DIFFERENTIATION	-0.29100130562234	-1.00747344351562	0.435141743210203	0.802128755556157	27	PLA2G2A,AGTR1,CSF1,LPL,ADIPOQ,PPARG,ABCA1,NR1H3,ABCG1
GO:0001825	blastocyst formation	GO_BLASTOCYST_FORMATION	0.295849008910795	1.01113434423197	0.436088853195101	0.803434635935802	29	TET1,MFN2,LATS1,ADA,SOX17,CDX2,ZP3,RRP7A,SRF,TJP1
GO:0048641	regulation of skeletal muscle tissue development	GO_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT	0.265362252963207	1.00828236321251	0.437203450754853	0.805047491926058	46	HDAC9,ADRB2,DDX17,CAPN3,NACA,HMGCR,HDAC4,USP2,SIX1,SHH,SOX17,GPC1,FLOT1,MEF2C,TWIST1,MYOCD,DKK1,RPS6KB1,USP19,SIX4
GO:0071549	cellular response to dexamethasone stimulus	GO_CELLULAR_RESPONSE_TO_DEXAMETHASONE_STIMULUS	-0.290494680778957	-1.00571946143487	0.437784973237296	0.805151221995528	27	ASS1,AQP1,ERRFI1,STAR,MSTN,HMBS
GO:0016242	negative regulation of macroautophagy	GO_NEGATIVE_REGULATION_OF_MACROAUTOPHAGY	0.335465919064963	1.01209787008351	0.437863230406447	0.805151221995528	18	UBQLN4,LRRK2,TSC1,PINK1,MTOR,NPC1
GO:1902116	negative regulation of organelle assembly	GO_NEGATIVE_REGULATION_OF_ORGANELLE_ASSEMBLY	0.340724746944185	1.01219498059186	0.438030055051332	0.805151221995528	17	LRRK2,PINK1,CAV3,MAP4,TBC1D30,CHMP4B,TCHP
GO:1901222	regulation of nik nf kappab signaling	GO_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING	-0.267233981652133	-1.00519123704439	0.438216589036188	0.805151221995528	38	CHI3L1,EZR,TRAF4,CARD14,IRAK1,RPS3,NLRP12,NOD1,RASSF2,DLG1
GO:1901889	negative regulation of cell junction assembly	GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.335217293662205	1.0113477693243	0.438773047143361	0.805733811611868	18	DLC1,ROCK2,PTEN,IKBKB,TNF,BCAS3,ACE,CLASP2
GO:0015949	nucleobase containing small molecule interconversion	GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_INTERCONVERSION	0.340453768449771	1.01138998161731	0.439108763576849	0.805910631515634	17	GSR,NUDT13,AK1,TXNRD1,AK4,GLRX
GO:0006836	neurotransmitter transport	GO_NEUROTRANSMITTER_TRANSPORT	-0.206148374414789	-1.0033915334947	0.439348531001277	0.805911256321689	146	STX19,SYT4,SNAP25,NLGN1,SYN1,RIMS4,SYTL1,SYT17,TRIM9,SNCA,SLC6A17,SLC18A1,SLC22A3,RPH3A,PDZD11,C2CD4D,SYN3,DDC,SLC17A7,SLC6A3,SNAP23,PCLO,STX11,SYT6,SLC18A2,CDK5,UNC13B,LIN7B,SLC38A1,SYT5,STX2,STXBP1,SLC6A14,CASK,SLC32A1,SYTL5,SNAPIN,SLC17A6,SLC6A9,PSEN1,SLC18A3,SYT1,HRH3,SLC6A12,WNT7A
NA	developmental programmed cell death	GO_DEVELOPMENTAL_PROGRAMMED_CELL_DEATH	0.306224693162923	1.00818438768553	0.439889156007414	0.80643855480156	25	LRP5,HAND2,NKX2-5,SPI1,FASLG,PRKDC,BAK1,CASP2
GO:0048557	embryonic digestive tract morphogenesis	GO_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS	-0.335342686693926	-1.0076203885295	0.440115158993008	0.80643855480156	16	FGFR2,FOXF1,SOX11
GO:0071396	cellular response to lipid	GO_CELLULAR_RESPONSE_TO_LIPID	-0.180922187741828	-1.00245614273552	0.440621089750882	0.806810604262186	417	ASS1,WNT6,CCL3,SSTR3,MLC1,OSR1,RARA,IL18,CYP26B1,SNW1,FFAR3,AQP1,BMP4,SSTR4,WNT5A,SSTR2,T,ENTPD2,LY96,WNT9A,CEBPB,PTK7,NR1I3,LPAR1,SGK1,HNF4G,TSPO,CALR,ANXA1,ACVR1,KLF4,IRAK1,XBP1,WNT10B,GNAI1,CTNNB1,P2RY4,ERRFI1,PYCARD,PIM1,AKR1C3,NR4A3,RIPK2,YWHAH,DGAT2,EGFR,STAR,MSX2,WNT7B,PAQR5,HIF1A,CPS1,LRP8,UBE2L3,MSTN,LEP,CCNB1,LILRB2,PPARG,ABCA1,PTGER2,CCNA2,NR1H3,EDNRB,IL24,SFR1,LTK,FAS,HMBS,ADCY2,NLRP3,MYOD1,ADCYAP1,ADAM9,MSN,HMGB2,ZNF703,FLT3,AHR,WNT9B,TLR2,CYP7A1,MDM2,EDN1,CEBPE,TESC,POU4F2,PIAS1,HNF4A,PTGER4,INHBA,MED13,PMEPA1,ABL1,PAWR,RET,SMARCD1,ESRRB,ATP2B1,SERPINF1,ATP1A1,IL10,WNT3,PTGFR,ACACA,NTS,ISL1,PDE4B,NRIP1,MED14,CCDC62,SSTR5
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	GO_IMMUNOGLOBULIN_PRODUCTION_INVOLVED_IN_IMMUNOGLOBULIN_MEDIATED_IMMUNE_RESPONSE	-0.299577824274212	-1.00574431668088	0.441003596806737	0.806810604262186	24	GCNT3,HLA-DRB5,EXOSC6,RNF8,POU2F2,HLA-DRB1,NBN,SWAP70
GO:0007187	g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER	-0.204445501946699	-1.00336360927849	0.441096297764782	0.806810604262186	155	MC3R,GPR26,CNR1,SSTR3,DRD5,FFAR3,SSTR4,SSTR2,APLP1,FSHR,LPAR1,NPY2R,OPRM1,ANXA1,INSL3,GNAI1,GNAT1,CNR2,HTR1F,HTR1B,HRH4,PTHLH,ADRA1D,NPBWR1,HTR5A,PTGER2,OR13F1,OPRD1,CHRM4,GNAZ,ADCY2
GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	GO_NEGATIVE_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION	-0.328498394734403	-1.00464802932451	0.441276982307393	0.806810604262186	17	HIST1H4C,HIST1H4D,HIST1H4E,NFE2L2,PF4,MIXL1,GABPA
GO:0021517	ventral spinal cord development	GO_VENTRAL_SPINAL_CORD_DEVELOPMENT	-0.255377969955813	-1.00421479428116	0.442247869798476	0.808146758817411	46	LHX4,NKX6-1,GBX1,GDPD5,HOXC10,OLIG3,MDGA2,EVX1,ISL2
GO:0060070	canonical wnt signaling pathway	GO_CANONICAL_WNT_SIGNALING_PATHWAY	0.233141358002897	1.0057168721644	0.442620096460223	0.808388087186713	88	LRP5,PROP1,LRP6,DVL2,DIXDC1,LRRK2,CCND1,RYR2,BCL9L,GSK3B,PTEN,CHD8,FZD10,TCF7L1,MED12,SHH,WNT8B,NKX2-5,ZNRF3,SOX17,APC,WNT11,CSNK1A1,FGF8,UBE2B,EGF,HOXB9
GO:0071108	protein k48 linked deubiquitination	GO_PROTEIN_K48_LINKED_DEUBIQUITINATION	0.334156476907754	1.00814729405479	0.443099318565832	0.808824461113118	18	VCPIP1,BAP1,YOD1,OTUD7A,USP5,USP34,ATXN3,USP20,USP19,TNFAIP3
GO:0031076	embryonic camera type eye development	GO_EMBRYONIC_CAMERA_TYPE_EYE_DEVELOPMENT	-0.275341541646992	-1.00200795843605	0.443708168964142	0.809241102609481	33	TRAF3IP1,RARA,RDH10,WNT5A,SOX11,WDR19
GO:0006521	regulation of cellular amino acid metabolic process	GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS	0.247475687775242	1.00398302664307	0.444165132417505	0.809241102609481	63	PSMD11,PSMD2,PSMC6,SIRT4,PSMC5,PSMB7,PSME4,PSMA8,PARK7,PSMD8,PSMB10,APC,PSMD3,PSMB1,OAZ1,PSMA5,PSMB9,HPN,PSMD6,ACMSD,PSMB3,PSMB6,PSMD1
GO:0060688	regulation of morphogenesis of a branching structure	GO_REGULATION_OF_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE	-0.24809862066279	-1.00161568821497	0.444265748521983	0.809241102609481	52	SULF1,PAX8,BMP4,WNT5A,FGF7,WNT2B,FGFR2,RTN4,CTNNB1
GO:0009072	aromatic amino acid family metabolic process	GO_AROMATIC_AMINO_ACID_FAMILY_METABOLIC_PROCESS	0.308644676192013	1.00572731038201	0.444289232805205	0.809241102609481	24	TPH2,ATP7A,TYR,HAAO,ASRGL1,IDO1,GCDH,TH,ACMSD,QDPR
GO:0045739	positive regulation of dna repair	GO_POSITIVE_REGULATION_OF_DNA_REPAIR	-0.277307951371497	-1.00142674102316	0.444656361579916	0.809406386650445	32	FOXM1,KDM4D,EGFR,CEBPG,RPS3,BRCC3,RNF8,SIRT1,PCNA,UBE2V2
GO:0070193	synaptonemal complex organization	GO_SYNAPTONEMAL_COMPLEX_ORGANIZATION	0.324463934654433	1.00717012757588	0.444948186528497	0.809406386650445	20	SYCP2,TEX11,RAD21L1,SPO11,MLH3,BAG6,UBE2B
GO:0014033	neural crest cell differentiation	GO_NEURAL_CREST_CELL_DIFFERENTIATION	-0.231682460184994	-1.00244574733663	0.445542492131087	0.809406386650445	73	SEMA3F,SEMA3C,RDH10,SOX11,GBX2,SEMA3A,SEMA3B,ACVR1,HIF1A,SEMA3D,GDNF,EDNRB,CORO1C,SEMA3E,SEMA4B,SEMA4A,EDN1
GO:1901607	alpha amino acid biosynthetic process	GO_ALPHA_AMINO_ACID_BIOSYNTHETIC_PROCESS	-0.234066478937175	-1.00140742607285	0.445606162244686	0.809406386650445	69	ASS1,SHMT1,GART,CARNS1,MTHFD1L,PYCR1,CPS1,PADI4,AGXT2,PSAT1,DHFR,GGT1,AGXT,OAT,LGSN,PYCR2,NOXRED1,MRI1,GOT1L1
GO:0070911	global genome nucleotide excision repair	GO_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR	0.289025158053182	1.00412458755437	0.446060738634292	0.809406386650445	31	CUL4A,RNF111,UBE2N,ERCC1,GTF2H3,ERCC4,GTF2H5,SUMO2,SUMO1,UBE2I
GO:0098656	anion transmembrane transport	GO_ANION_TRANSMEMBRANE_TRANSPORT	-0.191693609851238	-1.00125971866589	0.446153045559805	0.809406386650445	243	SLC22A24,SLC1A6,SLC26A9,CFTR,SLC34A1,SLC36A2,EMB,SLC22A4,BEST1,SLC1A1,ANO6,SLC7A3,SLC4A4,SLC17A5,GABRA4,CLCNKB,ANO3,SLC6A17,SLC38A2,SLC22A25,SLC7A10,SLC17A2,SLC17A7,SLC7A8,SLC7A2,CLIC3,SLC35A3,SLC22A20,GLRA4,SLC25A22,CLCA2,SLC1A4,ABCA1,SLC16A1,SLC38A1,SLC22A8,SLC13A5,SLC38A8,SLC6A14,SLC7A4,TTYH1,SLC32A1,SLC37A1,ANO7,SLC7A9,LRRC8E,SLC23A2,CLIC1,SLC17A6,GABRA6,SLC38A11,SLC6A9,CLCN5,AQP9,SLC20A1,GABRG2,ABCC4,SLC16A8,GABRB2,SLC7A13,SLC16A4,SLC6A12,ACACA,SLC7A11,SLC38A5,SLC12A3,SLC7A14
GO:0010888	negative regulation of lipid storage	GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE	-0.333571888303627	-1.00229958496693	0.44678225858822	0.809406386650445	16	PTPN2,LEP,PPARG,ABCA1,NR1H3,ABCG1,OSBPL8
GO:0006509	membrane protein ectodomain proteolysis	GO_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS	0.324041730965639	1.00585956298706	0.446909696521095	0.809406386650445	20	ADAM19,NCSTN,PSENEN,P2RX7,ADAM10,APH1A,PRKCQ,PSEN2,SPPL3
GO:0021884	forebrain neuron development	GO_FOREBRAIN_NEURON_DEVELOPMENT	0.288791204908881	1.00331179289625	0.447118013781035	0.809406386650445	31	NRP1,ATP7A,DRD2,OGDH,RAPGEF2,SLC4A10,FGFR1,FGF8,UQCRQ,PLXNA3,DCLK2
GO:0070585	protein localization to mitochondrion	GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION	0.248465100265448	1.00127639337686	0.447175797104018	0.809406386650445	61	BAD,MFN2,MOAP1,LRRK2,COX18,PINK1,MIPEP,PDE2A,AIP,TIMM8B,IMMP1L,MARCH5,PMPCA,TIMM17B,TIMM22,CHCHD4,BID,NDUFA13,TOMM40L,TIMM13,BMF,TOMM40
GO:0051101	regulation of dna binding	GO_REGULATION_OF_DNA_BINDING	0.232903083379511	1.00259557449272	0.447231803769904	0.809406386650445	87	CSNK2B,HABP4,HDAC2,PPARA,CALM3,HAND2,NFIB,HIPK2,NSD1,SP100,JAK2,KAT2A,LHX2,CALM1,EP300,ACD,CTNNBIP1,PARK7,HEY2,MDFI,HMGB1,SUMO1,NFKBIA,EGF,MSX1,TWIST1,SMO,MYOCD,ANKRD33,SIRT2,SIN3A
GO:1901658	glycosyl compound catabolic process	GO_GLYCOSYL_COMPOUND_CATABOLIC_PROCESS	0.274850906185892	1.00171215507663	0.4474397427095	0.809406386650445	38	CECR1,UPP2,ENTPD4,ADA,AICDA,APOBEC3H,NAGA,UPB1,FUCA2,APOBEC1,FUCA1
GO:0060004	reflex	GO_REFLEX	0.32855615687481	1.00542038236622	0.447576161885702	0.809406386650445	19	USP46,SHANK1,GJA1,HPN,SATB1,ASCL1,GLRA1,DRD3,SLITRK6,CACNA1A
GO:0042754	negative regulation of circadian rhythm	GO_NEGATIVE_REGULATION_OF_CIRCADIAN_RHYTHM	0.343876545648373	1.00478492277583	0.447746491961714	0.809406386650445	16	DRD2,SUV39H1,ADA,SFPQ,SIN3A,CRY2
GO:0055092	sterol homeostasis	GO_STEROL_HOMEOSTASIS	0.256769144812206	1.00176231287635	0.448787037865903	0.810695269657707	52	EHD1,LRP5,ABCA2,TMEM97,APOC3,LDLR,LCAT,PCSK9,CAV3,MALL,LIPG
GO:0031146	scf dependent proteasomal ubiquitin dependent protein catabolic process	GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS	0.311265082729137	1.00359602675098	0.449175269093714	0.810695269657707	23	FBXL7,FBXO6,FBXW7,BTRC,FBXO31
GO:0050912	detection of chemical stimulus involved in sensory perception of taste	GO_DETECTION_OF_CHEMICAL_STIMULUS_INVOLVED_IN_SENSORY_PERCEPTION_OF_TASTE	0.26874024289813	1.00105157161716	0.44927797833935	0.810695269657707	42	TAS2R42,TAS2R13,TAS2R38,TAS2R4,TAS2R10,TAS2R20,TAS1R2,GNAT2,TAS2R31,PIP,PKD2L1,TAS2R9,TAS2R19,RTP4,CA6,TAS2R1,TAS2R14,TAS2R3,TAS1R3,TAS2R46
GO:0030641	regulation of cellular ph	GO_REGULATION_OF_CELLULAR_PH	-0.23363694616999	-0.99956975454998	0.44942286784946	0.810695269657707	69	SLC26A9,CFTR,ATP6V1C2,ATP6V1B1,SLC4A4,RAB38,ATP6V0D1,ATP6V1H,SLC17A7
NA	regulation of transcription from rna polymerase iii promoter	GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_III_PROMOTER	0.332418784545903	1.00290469074298	0.450192175576063	0.811632978842997	18	ELL,ZC3H8,CHD8,POLR3F,AR,MTOR,BDP1,PRDX5,RPTOR
GO:0031057	negative regulation of histone modification	GO_NEGATIVE_REGULATION_OF_HISTONE_MODIFICATION	0.284067558132654	1.00145027804954	0.450528425655977	0.811632978842997	33	SMARCB1,JARID2,TRIP12,KDM5A,UCN,UBR5,SPI1,BCOR,UBE2B,TWIST1,SIN3A,FOXP3
NA	maturation of 5 8s rrna	GO_MATURATION_OF_5_8S_RRNA	0.3012691212442	1.00178427659538	0.450668329085608	0.811632978842997	26	NOL9,WDR12,EXOSC4,ABT1,EXOSC7,EXOSC3,FTSJ3
GO:0001885	endothelial cell development	GO_ENDOTHELIAL_CELL_DEVELOPMENT	-0.258033371460222	-0.998925076094347	0.450907210468332	0.811632978842997	43	EZR,MET,GSTM3,MARVELD2,CTNNB1,TJP2,TNMD,WNT7B,RAPGEF3,RAP2B,MSN,F11R,ARHGEF26
GO:0034612	response to tumor necrosis factor	GO_RESPONSE_TO_TUMOR_NECROSIS_FACTOR	-0.19538109523813	-0.999722211631682	0.45115103874228	0.81163783880626	207	TNFRSF8,CHI3L1,KRT8,ASS1,EDA2R,CCL3,TNFSF11,CCL19,TNFRSF21,TNFSF14,TNFRSF11B,ENTPD2,NPNT,GATA3,KRT18,GPD1,TXNDC17,CARD14,EDAR,TJP2,PYCARD,CCL21,RIPK1,CHUK,TRADD,UBA52,TNFRSF1A,ADIPOQ,CASP3,PSMB11,TNFRSF25,FAS,PSMD10,INPP5K,CLDN18,ADAM9,PSMD5,CCL4,PSMD13,PSMB5,EDN1,FOXO3,NFE2L2,CCL18,UBB
GO:0006297	nucleotide excision repair dna gap filling	GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_GAP_FILLING	-0.307784135337513	-0.996440376437118	0.452388747026343	0.811863331649547	21	RPA3,XRCC1,UBA52,RPA2,UBB,PCNA,POLD1,RFC1,RPS27A,RFC4,RFC2
GO:0044062	regulation of excretion	GO_REGULATION_OF_EXCRETION	-0.290944914709905	-0.997219165538729	0.452499835030684	0.811863331649547	26	NPR1,ANPEP,TACR1,AGTR1,NPHS1,EDNRB,EDN1,PTGER4
GO:0035136	forelimb morphogenesis	GO_FORELIMB_MORPHOGENESIS	-0.266440733783899	-0.99654370427562	0.452563386574333	0.811863331649547	37	GDF5,OSR1,RDH10,WNT9A,CTNNB1,MSX2,RSPO2
GO:0003081	regulation of systemic arterial blood pressure by renin angiotensin	GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_BY_RENIN_ANGIOTENSIN	-0.307723051883488	-0.996242620890503	0.45271612213274	0.811863331649547	21	CMA1,CPA3,TACR1,AGTR1,MME
GO:0071559	response to transforming growth factor beta	GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA	-0.207457097178723	-0.998681137364668	0.452918421310352	0.811863331649547	136	CGN,GDF5,AMHR2,TGFBR1,WNT5A,FMOD,SKIL,GDF10,ACVR1,FUT8,MEN1,STAR,LEFTY1,UBA52,MSTN,SOX6,SMAD2,HPGD,LTBP2,RAPGEF3,IL1R1,WWOX,ADAM9,F11R,RHOA,NODAL,FSHB,EDN1,PDGFD,UBB,USP9Y
GO:0023058	adaptation of signaling pathway	GO_ADAPTATION_OF_SIGNALING_PATHWAY	0.327289138937523	1.00154315884653	0.452950114891409	0.811863331649547	19	ADRB2,DRD2,GIPR,GRK6,GRK4,ADM,ADRB3,DNM2,DRD3
GO:1901890	positive regulation of cell junction assembly	GO_POSITIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.306838978555679	0.999843394127374	0.452964746535309	0.811863331649547	24	AGT,TSC1,TEK,ACE2,VEGFA,SMAD3,LIMS1,FLOT1
GO:0051341	regulation of oxidoreductase activity	GO_REGULATION_OF_OXIDOREDUCTASE_ACTIVITY	0.23220170193251	0.99957628456066	0.453363994285913	0.812117410222924	87	AGT,ATP7A,LRRK2,CALM3,ESR1,OXA1L,TMLHE,FTMT,DAOA,GSK3B,CAV3,CYP27B1,SIRT4,AGTR2,CALM1,NOSIP,WASL,TNF,PARK7,HDAC6,ENG,CCS,RFK,NFKB1,FXN,ABL2,ECSIT,ZDHHC21,SPR,PRDX5,MT3,CYGB
GO:0035455	response to interferon alpha	GO_RESPONSE_TO_INTERFERON_ALPHA	-0.320745248882294	-0.996059573152368	0.453591938454871	0.812117410222924	18	IFITM2,ENTPD2,GATA3,STAR
GO:0030903	notochord development	GO_NOTOCHORD_DEVELOPMENT	-0.320696826690577	-0.995909200269897	0.453830317477517	0.812117410222924	18	WNT5A,T,CRB2,COBL
GO:0071312	cellular response to alkaloid	GO_CELLULAR_RESPONSE_TO_ALKALOID	-0.277499462942028	-0.993984050011731	0.455165692007797	0.814074239797155	31	SLC34A1,RYR1,OPRM1,DDC,STAR,HTR1B,CCNA2,RYR3
NA	regulation of g protein coupled receptor protein signaling pathway	GO_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY	0.220412022587731	0.998849696920924	0.455672913117547	0.814548606241988	118	RGS9,RHO,RGS5,RGS3,ADRB2,LRRK2,CALM3,DRD2,GIPR,RGS11,PLCE1,ABHD6,RGS20,MGLL,RGS18,GUCA1C,NMT1,CALM1,CAMKMT,ADA,GPSM1,RAMP3,RGS14,KCTD16,GRK6,RGS13,GRK4,METAP1,RPH3AL,GPRASP1
GO:1901522	positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus	GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_INVOLVED_IN_CELLULAR_RESPONSE_TO_CHEMICAL_STIMULUS	0.300209225424128	0.998259896257313	0.456352335026311	0.814980804064361	26	CHD6,SMAD1,RXRG,EP300,RXRA,VEGFA,USF2,SMAD9,NCOA1,MT3,USF1,PPARGC1A
GO:0031650	regulation of heat generation	GO_REGULATION_OF_HEAT_GENERATION	-0.337851961684026	-0.995300807686101	0.456398935134082	0.814980804064361	15	CNR1,TNFSF11,EDNRB,ABAT,PLA2G4A
GO:0016236	macroautophagy	GO_MACROAUTOPHAGY	0.199057840495859	0.999642412129246	0.456857475879039	0.81501421149756	252	DPF3,C6orf106,WDFY3,RRAGB,OBSCN,MYOM1,SCN1A,MAP1A,ATG14,TP53INP2,DYNLL2,ATPIF1,TNIK,MFN2,ACIN1,RRAGD,ULK1,CALCOCO2,ATG16L1,HIST1H3G,SLC6A1,PRKAB2,MFN1,NDUFB9,HIST1H3B,PINK1,PRKAA2,PIK3C3,WIPI2,MDH1,DZANK1,PI4K2A,MTSS1,MYLK,PFKP,MTOR,LSM4,ADAMTS7,ATG9A,HDAC6,ALKBH5,VDAC1,CD93,HIST1H3E,REP15,MAP1LC3A,C1orf210,ZNF189,ITPKC,CA7,MLST8,WDR45,ATG16L2,PRKAG3,PRKG1,FAM13B,MTMR14,UVRAG,CAPS,MAP1LC3B,ACBD5,FCGR3B,MBD5,TSG101,CALCB,EIF2S1,RIMS3,PRKAG1,AMBRA1
GO:0042698	ovulation cycle	GO_OVULATION_CYCLE	-0.215466696977074	-0.996627111965725	0.456901906445602	0.81501421149756	106	TYRO3,BMP4,WNT5A,FGF7,CEBPB,FSHR,OPRM1,ANXA1,FANCF,HAS1,SGPL1,BMPR1B,SLIT3,ROBO2,MSTN,LEP,FAS,ADCYAP1,BAX,AHR,AFP,FSHB,GPR149,FOXO3,INHBA,SIRT1,FOXL2,TIMP4,SERPINF1,MMP19,MMP14,BCL2,PLA2G4A
GO:0034243	regulation of transcription elongation from rna polymerase ii promoter	GO_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER	0.321580038277154	0.998218210361059	0.457660991857883	0.815578746050225	20	PAF1,ELL,EZH2,SHH,RECQL5,RNF168,GTF2F2
GO:0051702	interaction with symbiont	GO_INTERACTION_WITH_SYMBIONT	-0.247176688435522	-0.993747005629366	0.457729249728162	0.815578746050225	51	PPIB,CCL3,SNW1,AQP1,PC,EIF2AK4,MBL2,INPP5K,CCL4,ELANE,CAMP,JUN,LTF,APOE,RAB9A,GPX1,TFAP4,VAPA,SUGT1,CAV2,CHD1,TUSC2
NA	modulation by virus of host morphology or physiology	GO_MODULATION_BY_VIRUS_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY	0.280861426511735	0.997068544335247	0.457945285215367	0.815578746050225	34	BAD,HIPK2,CCR2,RXRA,KPNA4,KPNA3,HYAL2,SMAD3,VAPB,NTRK3,CD4,KPNB1,EIF2AK2,INSR,DAG1,TGFB1
GO:0097193	intrinsic apoptotic signaling pathway	GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	-0.206642022351232	-0.995902444040527	0.459370792018607	0.817352869479503	137	EDA2R,BBC3,SFN,PHLDA3,SNW1,NUPR1,CEBPB,LGALS12,ZNF385C,CYCS,CRIP1,CHAC1,XBP1,TP73,BOK,BRSK2,PYCARD,MELK,CDKN1A,TNFRSF1A,ZMAT3,RPS27L,ARL6IP5,CHEK2,SART1,BAX,EPHA2,WWOX,CUL1,DNAJC10,IFI16,IKBKE,ABL1,SIRT1,NBN,BCL2,PDCD10,HRAS,STK24,E2F2,CYP1B1,HINT1,MAP3K5,XPA
GO:0009147	pyrimidine nucleoside triphosphate metabolic process	GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS	-0.330429228464586	-0.992856682963464	0.4595320042427	0.817352869479503	16	DTYMK,DUT,NME9,TYMS
GO:0034103	regulation of tissue remodeling	GO_REGULATION_OF_TISSUE_REMODELING	0.253061090453125	0.994777791461568	0.459669929270558	0.817352869479503	54	LRP5,AGT,ITGB3,ABR,GJA1,SYT7,INPP5D,ERG,S1PR1,CA2,P2RX7,IL2,CD38,ATP6AP1
GO:0070232	regulation of t cell apoptotic process	GO_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS	-0.274695389797315	-0.991992143096859	0.460025282207092	0.817552851060756	32	BBC3,BMP4,WNT5A,HIF1A,RIPK3,LGALS16,RAG1,PRELID1
GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GO_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	0.271465089389303	0.99472595622635	0.460327501445922	0.817658242673866	39	BAD,DYNLL2,ATPIF1,GZMB,GSK3B,NMT1,PPP3R1,PPP1R13B,TMEM102,BID,MAPK8,YWHAG,BAK1,TP53BP2
GO:0007043	cell cell junction assembly	GO_CELL_CELL_JUNCTION_ASSEMBLY	-0.231757755827243	-0.994737518670276	0.460891660891661	0.818228549874119	70	CLDN1,PRKCA,PARD6B,OCLN,LSR,GRHL2,PRKCI,MPP7,MARVELD2,DLG5,RAB13,MPP5
GO:0042730	fibrinolysis	GO_FIBRINOLYSIS	-0.305779756476206	-0.989951269957043	0.461293349920339	0.818509971445367	21	SERPING1,ANXA2,F2,PLAUR,SERPINB2,PROS1
GO:0002687	positive regulation of leukocyte migration	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MIGRATION	-0.215037769073816	-0.99464313400782	0.461679965597974	0.81866328252239	106	CCL3,CCL19,BDKRB1,WNT5A,CCR6,TNFSF14,ANO6,CALR,TACR1,CXCL1,F7,MIA3,PYCARD,CCL21,CSF1,C5AR1,RARRES2,CMKLR1,THBS1,CCL4,PDGFD,PTGER4,THBS4,CXCL5,PAWR,SWAP70,PF4
GO:1901186	positive regulation of erbb signaling pathway	GO_POSITIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY	0.283616275000595	0.992926584771808	0.462056782793976	0.81866328252239	32	AGT,FBXW7,ESR1,ARAP1,ADRA2C,TGFA,ESR2,AGR2,FASLG,PDE6H,EGF
GO:0051235	maintenance of location	GO_MAINTENANCE_OF_LOCATION	-0.208863190819953	-0.993766830698779	0.462542149244979	0.81866328252239	127	EZR,PLIN2,MORC3,KDELR3,ARL2BP,GAA,CIDEA,TSPO,CALR,SPTBN4,ANGPTL3,SLC17A7,TWF1,DGAT2,KDELR2,ACVR1C,TBCCD1,SLC18A2,HK2,SORL1,KEAP1,S100A9,SCIN,PSMD10,SLC30A8
GO:0015718	monocarboxylic acid transport	GO_MONOCARBOXYLIC_ACID_TRANSPORT	0.221023588497042	0.994473062572997	0.462577589302509	0.81866328252239	113	SLC10A5,SLC25A17,PPARD,SLC27A5,SLCO3A1,DRD4,PPARA,DRD2,CEACAM1,SLC6A1,PRKAB2,PLA2G5,ABCC2,SLC10A4,PRKAA2,SLC5A6,GOT2,SLC16A12,SLC27A6,RXRA,SLC16A14,SLC10A6,FABP3,SLCO1B1,NMUR2,ABCB4,NCOA1,ATP8B1,ACACB,CD36
GO:0000187	activation of mapk activity	GO_ACTIVATION_OF_MAPK_ACTIVITY	-0.208293203674428	-0.99387819401327	0.462595829874506	0.81866328252239	129	EPGN,TNFSF11,CCL19,MAPK10,WNT5A,BMP2,MAP2K2,LPAR1,ALK,MDFIC,IRAK1,TP73,RIPK2,RIPK1,UBA52,SAA1,C5AR1,IKBKG,PAK3,HGF,C5,MAP3K11,THBS1,NOD1,FCER1A,MAP3K2,MAPK11,UBB,MOS,AVPI1,AXIN1,GNG3,FGF2,TAB2,CD81,MAP2K5,MAP3K5,PDE6G,MAP3K7,FGF10,MAP3K9,MAP4K5,PEA15
GO:0090307	mitotic spindle assembly	GO_MITOTIC_SPINDLE_ASSEMBLY	0.272310032995173	0.992451776077077	0.463014490658765	0.818799567990786	38	TUBGCP5,BIRC8,CLASP1,TUBGCP2,GOLGA2
GO:0051282	regulation of sequestering of calcium ion	GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION	0.226317451000449	0.994234651426183	0.463159351590748	0.818799567990786	98	PRKACA,ANK2,ITPR1,TRPV1,CALM3,RYR2,TPCN1,CAPN3,XCL1,ATP1A2,DRD2,HRC,CXCL11,AKAP6,DMD,CXCR3,PLN,SLC8A1,CALM1,CACNA1C,P2RX7,CYBA,CXCL9,PLCG1,HTT,TRDN,JPH2,PRKCE
GO:2000179	positive regulation of neural precursor cell proliferation	GO_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION	0.270840731236465	0.992438128859648	0.463906159629844	0.819689308826275	39	ELL3,GLI2,DRD2,SMARCD3,SHH,CX3CL1,DLL4,VEGFA,PAX6,LHX1,EGF,PROX1,ASCL1,NES,SMO,GNG5
GO:0033189	response to vitamin a	GO_RESPONSE_TO_VITAMIN_A	-0.318196528543383	-0.988144639722467	0.464514031856106	0.820143067644956	18	SLC34A1,RARA,CAT,TYMS,PPARG
GO:0007158	neuron cell cell adhesion	GO_NEURON_CELL_CELL_ADHESION	0.339423872792117	0.991774502005251	0.465031130935787	0.820143067644956	16	NLGN3,NRXN1,CEL,NLGN4X,NCAM2,NLGN2
GO:0035690	cellular response to drug	GO_CELLULAR_RESPONSE_TO_DRUG	0.246049410363393	0.991541532142574	0.465253531361324	0.820143067644956	61	EIF2B5,PPAT,NKX3-1,REST,PRKAA2,ACER2,KCNH2,PPP1R14A,PDE2A,EP300,ESR2,ADSSL1,PPP1R12A,CRHBP,CAD,TH,MEF2C,UMPS,MT3,QDPR,RBM22,NOS2,PRNP,GPLD1,PPP3CB,PPP1R15A
GO:0002053	positive regulation of mesenchymal cell proliferation	GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION	0.295678778986761	0.992449442847676	0.465542186326759	0.820143067644956	27	LRP5,FBXW4,TGFBR2,SIX1,SHH,FGFR1,VEGFA,SOX9
GO:0060037	pharyngeal system development	GO_PHARYNGEAL_SYSTEM_DEVELOPMENT	-0.322795942693759	-0.987208196141821	0.465566466236968	0.820143067644956	17	TGFBR1,GATA3,ACVR1,PLXNA2
NA	negative regulation of glucose transport	GO_NEGATIVE_REGULATION_OF_GLUCOSE_TRANSPORT	-0.328885446549677	-0.988218006783462	0.465722882438254	0.820143067644956	16	MZB1,OSTN,LEP,SIRT6,INPP5K,LMBRD1
GO:0051875	pigment granule localization	GO_PIGMENT_GRANULE_LOCALIZATION	-0.301371097012121	-0.988030427772226	0.46586855179357	0.820143067644956	22	RAB27B,BBS7,GPR143,VPS33A,RAB17,SHROOM2,RAB11A,BLOC1S3,ASIP
GO:0032768	regulation of monooxygenase activity	GO_REGULATION_OF_MONOOXYGENASE_ACTIVITY	-0.240697970833237	-0.990644205984029	0.466589284901452	0.820758216327425	57	CNR1,PRKG2,KRAS,SNCA,CNR2,EGFR,PTS,HIF1A,CDH3,LEP,DHFR,GDNF,DDAH2,NOD1,HSP90AA1
GO:0010256	endomembrane system organization	GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION	0.187480244895251	0.996870322748958	0.466705652421477	0.820758216327425	433	ZFYVE27,P2RY1,KIFC3,DYSF,RILPL1,MTSS1L,RAB30,LPIN1,AKT2,POM121,SUN1,VCPIP1,ANK2,CLASP1,KIF13A,TNIK,TMEM88,LRP6,PAFAH1B1,GAK,ALS2,VPS4A,RAPGEF6,DMPK,ROCK2,LRRK2,SH3TC2,ARFGEF2,CLIP1,PPIL2,FABP9,NUP85,SYTL2,VAMP2,CDH2,PACSIN2,GOLGA2,MACF1,RAE1,SYT7,VPS11,RAPGEF2,CAV3,OBSL1,PTEN,CHMP7,PIK3C3,SGIP1,PKP2,VPS37B,TMEM127,GOLGA4,TUB,NFASC,GORASP1,SUN5,VTI1A,ARL1,MTSS1,PLEKHM2,PRKCZ,FNBP1L,RAMP3,NUP188,IKBKB,CREB1,TNF,NEK9,EMD,FAT4,CDK1,BAG4,PTCH1,CRB1,ARFGEF1,BANF1,ARHGAP21,P2RX7,SOD1,TSPAN17,COG2,EFR3B,ANK3,LEMD2,SYNE2,NPLOC4,VPS37C,RDX,UBL4A,FAM126A,BAG6,CSNK1A1,ATP8B1,HTT,GBF1,TRDN,LAMA5,TTC7B,FASLG,CHMP6,DYM,SUMO1,TPR,AAAS,VAPB,PARP11,ATP2A2,BCAS3,CALCR,POM121C,UBXN2B,SCP2,FLOT1,TSG101,EMP2,AKAP8L,TMEM150A,JUP,SEC23IP,EFR3A,VPS37A,TSPAN14,SYP,PACSIN1,PLSCR2,SEC16A,SPTBN1,CTDNEP1,NUP214,CLCN3,ACTN2,GOLPH3,CHMP1B,CLASP2
GO:0048247	lymphocyte chemotaxis	GO_LYMPHOCYTE_CHEMOTAXIS	0.28272066996806	0.989791115743249	0.467301633552476	0.82137717939302	32	CCL1,XCL1,CCL24,CXCL11,CXCR3,CX3CL1,CCR2,CCL16
GO:1904376	negative regulation of protein localization to cell periphery	GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY	-0.313333470159706	-0.986860696207717	0.467722316347365	0.82154956491607	19	DAB2,ANXA13,RHOQ,PPP2R5A,TMEM59
GO:0055081	anion homeostasis	GO_ANION_HOMEOSTASIS	-0.262542691516844	-0.987545113953037	0.467887853815837	0.82154956491607	38	SLC34A1,CA12,XBP1,ANGPTL3,DGAT2,CPS1,ABCA1,ABCG1,FGFR4,GPAM,HNF4A,SIRT1
GO:1903533	regulation of protein targeting	GO_REGULATION_OF_PROTEIN_TARGETING	0.196346532123099	0.995578745344133	0.468658728375646	0.822182160113834	273	PARL,PIK3R1,RBCK1,AKT2,FBXW7,PYDC2,GPHA2,ATPIF1,LRRK2,AKAP1,ITGAX,RNF31,C8orf4,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,SUFU,PKIA,GSK3B,AKAP6,JAK2,DDX58,SIAH3,CSF3,HUWE1,SIRT4,CYB5R1,CABP1,RGS20,MBTPS1,PSMB7,AGTR2,KAT2A,UBR5,PDE2A,SHH,SAE1,NUCB1,EP300,ERBB4,PPP3R1,MTOR,IL18R1,TNF,SEMA5A,TMEM173,EMD,ARIH2,CDK1,PSMD8,BAG4,USP36,FAF1,ANK3,KANK1,MDFI,HYAL2,CD36,SMAD3,TPR,KCNN3,BAMBI,LITAF,NFKBIA,EGF,TLR4,TGFB3,FAM89B,MED1,EDA,PRKCQ,WBP11,JUP
GO:0050853	b cell receptor signaling pathway	GO_B_CELL_RECEPTOR_SIGNALING_PATHWAY	-0.255497564490438	-0.989108201804338	0.468736650403579	0.822182160113834	43	CD79B,IGHG4,IGHG2,IGHG1,IGHD,BAX,IGKC,IGLL1,IGLC1,ABL1,BCL2,ZAP70,IGHA1,RFTN1,CD19,PTPN6,PLCG2
NA	maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 	GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_	-0.273035061894732	-0.985996293528568	0.469339779556896	0.822498298162015	32	RPS19,WDR46,RPS8,NOC4L,RPS24,RPS16,KRR1
GO:0001963	synaptic transmission dopaminergic	GO_SYNAPTIC_TRANSMISSION_DOPAMINERGIC	0.333087448218488	0.989506768171831	0.469405594405594	0.822498298162015	17	SLC6A2,DRD4,DRD2,GPR52,PARK7,CRHBP,TH
GO:1904427	positive regulation of calcium ion transmembrane transport	GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT	0.252576818914439	0.989322309170745	0.469979629033987	0.822659041805685	53	ANK2,CALM3,CACNA2D1,RYR2,S100A1,CAPN3,XCL1,CXCL11,AKAP6,CXCR3,CALM1,CXCL9,PLCG1,HTT,TRDN,SUMO1,JPH2
GO:0033365	protein localization to organelle	GO_PROTEIN_LOCALIZATION_TO_ORGANELLE	-0.176718786152481	-0.995153415811984	0.470555555555556	0.822659041805685	496	C5orf42,GDF5,RPL24,LRWD1,SRP72,RPL38,BBC3,CNGB1,MORC3,KDELR3,ARL2BP,PEX10,RPL35,PEX5L,SEC63,BMP4,PYGO1,RPL30,RGPD3,RPL9,AP3M1,WDR35,RPL3,CNTLN,RPS3A,RPS19,TSPO,CALR,SEC61G,RPS27,TIMM10,RPL4,BANP,IPO5,TIMM9,RPS11,MID2,RPL7A,RPS4Y1,VPS25,CTNNB1,SLC25A6,STAT3,TOR1A,MIS12,MTX1,TOB1,RPS8,AKR1C3,BCAP31,SH3GLB1,RPL18,KPNA7,SPRN,KDELR2,SNX10,RAB3GAP2,SNF8,RPS24,TULP1,RPL18A,UBA52,RAB10,RPL15,RPS16,ABCA7,RPL5,HK2,RPL10A,RPS3,SORL1,NUP50,TOMM34,TULP2,RPL22,FGF9,SRP54,CCDC14,GCC2,SPCS1,RPS29,OPRD1,RPL26,RPL19,TOMM5,PCM1,IFT20,SRP14,AURKB,BAX,SNX16,RPS28,F2R,WRB,RPS5,MID1,HSP90AA1,RPS17,TULP3,MFF,ZW10,MDM2,OSBPL8,SEC61A1
GO:0045069	regulation of viral genome replication	GO_REGULATION_OF_VIRAL_GENOME_REPLICATION	-0.233546515639174	-0.989554220333135	0.470752862264369	0.822659041805685	66	IFITM2,PPIB,SLPI,TARBP2,BTBD17,PABPC1,APOBEC3F,TOP2A,TRIM38,PPIH,EIF2AK4,INPP5K
GO:0032645	regulation of granulocyte macrophage colony stimulating factor production	GO_REGULATION_OF_GRANULOCYTE_MACROPHAGE_COLONY_STIMULATING_FACTOR_PRODUCTION	-0.334307376805495	-0.984858576790271	0.470813583533537	0.822659041805685	15	IL18,IL17F,TLR9,FCER1A,ISL1,IL23R,PAEP
GO:0007127	meiosis i	GO_MEIOSIS_I	0.238396545978227	0.989701152397793	0.47179053458787	0.822659041805685	71	SUN1,DMC1,SYCP2,SPANXA2-OT1,TEX11,KLHDC3,RAD21L1,SPO11,ERCC4,MLH3,CNTD1,PRDM9,HFM1,CCNA1,BAG6,DMRTC2,MRE11A,UBE2B,UBR2,ESPL1,CCDC155,BRCA2,TOP2B,MLH1,PLK1,MEI1
GO:0048545	response to steroid hormone	GO_RESPONSE_TO_STEROID_HORMONE	0.185923798609785	0.995556953238683	0.471867886768817	0.822659041805685	469	NR1I2,TK1,CCL1,RGS9,NR3C2,TSHB,NASP,CATSPERG,BAD,PPARD,TPH2,ESRRA,OPRL1,PDGFB,SCGB1A1,STAT5B,CATSPER2,NR2F6,GPR83,ABCA2,DRD4,NPY1R,HSD11B2,PRDM2,ADRB2,PPARA,CRIPAK,ROCK2,CALM3,ESR1,CCND1,CYP17A1,ATP1A2,OPRK1,SLC6A1,LCAT,RNF14,ADCYAP1R1,CTNNA1,UGT3A2,ABHD2,NKX3-1,TACR3,ABCC2,GSK3B,JAK2,PTEN,REST,CYP27B1,GH1,MED24,UCN,PLN,PTPRN,PSPH,TGFBR2,MED12,RXRB,AGTR2,UBR5,H2AFZ,EZH2,ZNF366,PDCD7,AR,CALM1,RXRG,ALAD,WNT8B,EP300,PTGDS,MED17,RAMP3,RHOXF1,ESR2,THRAP3,FOXO1,HMGCS2,TNF,TEK,RBBP5,CDKN1B,FHL2,RXRA,MAPK1,CITED4,TRIM24,PTCH1,CA2,NCOA3,TIMP3,ESRRG,ETS1,PELP1,TRIP4,NPC1,IDH1,ELK1,MAOB,GOT1,CRHBP,PTAFR,IL17A,CD38,NCOA1,HMGB1,CATSPER4,ABCG2,ENDOG,NR2F1,GNRH1,ATP1A3,WBP2,DDX54
GO:0051668	localization within membrane	GO_LOCALIZATION_WITHIN_MEMBRANE	0.219360583293379	0.991087157356881	0.472288621772982	0.822659041805685	116	SHANK3,RILPL1,MADCAM1,NRXN1,DLG4,SEC24C,CLIP1,MUSK,TRAPPC9,CDH2,GOLGA2,DLG2,F8,RAB1B,GRIA1,GORASP1,DNAJA3,TGFA,GRIK5,CDH13,ITGB2,MAL,PPP6R1,ITGAL,GPHN,TRAPPC5
GO:0043331	response to dsrna	GO_RESPONSE_TO_DSRNA	0.241330887157484	0.98867248684294	0.472686596085754	0.822659041805685	66	ADAR,METTL3,NPM1,ZCCHC11,SMAD1,DDX58,PELI1,LIN28B,IFIT1,SRRT,TMEM173,MAPK1,HNRNPA2B1,P2RX7,DICER1,NFKB1,SMAD3,IFNA21,NFKBIA,FLOT1,IFNA4,TICAM1
GO:0050999	regulation of nitric oxide synthase activity	GO_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY	-0.250857142788446	-0.986437687177351	0.473017447364862	0.822659041805685	46	CNR1,PRKG2,KRAS,CNR2,EGFR,PTS,HIF1A,LEP,DHFR,DDAH2,NOD1,HSP90AA1
GO:1901216	positive regulation of neuron death	GO_POSITIVE_REGULATION_OF_NEURON_DEATH	0.243525507194123	0.987957556459431	0.473073927205778	0.822659041805685	63	BAD,FBXW7,PIN1,PCSK9,ZNF746,HDAC4,GSK3B,GRIK5,UBE2M,AIMP2,EPHA7,MTOR,IKBKB,ATF2,ELK1,FASLG,DDIT4,EIF2S1,TP53BP2,CDC34,AIFM1,ASCL1,CASP2,MAP2K7
GO:0048333	mesodermal cell differentiation	GO_MESODERMAL_CELL_DIFFERENTIATION	-0.290190775155714	-0.984363320998502	0.47311638944431	0.822659041805685	25	ITGA3,BMP4,FGFR2,FOXF1,KLF4
GO:1901264	carbohydrate derivative transport	GO_CARBOHYDRATE_DERIVATIVE_TRANSPORT	0.260959333891307	0.987046731341902	0.473296037128312	0.822659041805685	45	SLC17A3,SLC25A17,SLC29A2,VLDLR,GJA1,RFT1,LBP
GO:0032897	negative regulation of viral transcription	GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION	-0.293125016489339	-0.984080914952156	0.473418720940433	0.822659041805685	24	CCL3,TRIM11,MID2,TRIM62,INPP5K,CCL4,TRIM27,JUN
GO:1903725	regulation of phospholipid metabolic process	GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS	0.248447342294415	0.987269459253188	0.473423230593607	0.822659041805685	57	PIK3R1,PDGFB,ATG14,FLT1,LDLR,ARF1,PIK3R3,IRS1,ERBB4,TEK,PIK3R5,PIK3IP1,FABP3,IDH1,ZP3,SLC27A1,AMBRA1,PIK3R6,PIK3R2
GO:0030520	intracellular estrogen receptor signaling pathway	GO_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY	0.337451266052014	0.986010673282112	0.473543350989685	0.822659041805685	16	ESR1,ESR2,TRIP4,DDX54,SAFB,PPARGC1B,ARID1A,DEFA3,CARM1,RBFOX2
GO:0003073	regulation of systemic arterial blood pressure	GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE	0.232664931965542	0.98892055139878	0.473617826361152	0.822659041805685	81	AGT,PDGFB,ADRB1,SERPINF2,HSD11B2,ADRB2,WNK1,DRD2,GJA1,AGTR2,TNNI3,NCALD,SLC4A5,GJA5,ACE2,SOD2,CYBA,ENG
GO:0008630	intrinsic apoptotic signaling pathway in response to dna damage	GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE	-0.235248963055181	-0.988533593954412	0.473824516247644	0.822659041805685	63	SFN,PHLDA3,SNW1,NUPR1,CRIP1,TP73,BOK,PYCARD,CDKN1A,TNFRSF1A,RPS27L,CHEK2,BAX,EPHA2,IFI16,IKBKE,ABL1,SIRT1
GO:0032663	regulation of interleukin 2 production	GO_REGULATION_OF_INTERLEUKIN_2_PRODUCTION	-0.250721902647189	-0.985905886604835	0.473896578152473	0.822659041805685	46	EZR,GATA3,ANXA1,RIPK2,IRF4,IL17F,CD34,VTCN1,ABL1,CARD9,IL20RB,CD276,TRIM27,PDE4B,HDAC7,MAP3K7,SASH3,IL1A,CD3E
GO:0050680	negative regulation of epithelial cell proliferation	GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION	-0.213378455736179	-0.989503951349193	0.474186509363835	0.822738036349829	108	GDF5,CDKN2B,SCG2,SFN,SULF1,TGFBR1,IFT57,BMP4,WNT5A,SFRP2,GATA3,FGFR2,MEN1,WNT10B
GO:0001702	gastrulation with mouth forming second	GO_GASTRULATION_WITH_MOUTH_FORMING_SECOND	-0.286639409106062	-0.982461964129082	0.475485559685898	0.824262804714591	26	WNT5A,T,UGDH,ACVR1,OTX2,CTNNB1
GO:0060491	regulation of cell projection assembly	GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY	-0.205167001399055	-0.989813333329131	0.475818114965069	0.824262804714591	138	HAP1,EPS8L1,KLF5,CCL19,NLGN1,AGRN,TGFBR1,GPM6A,FAM110C,GAP43,EVL,COBL,CCL21,TBC1D2B,TBC1D2,RHOQ,DPYSL3,CDC42EP1,TBC1D9B,RHOG,IFT20,CORO1C,EPHA2,RALA,SSH3,HSP90AA1,RAB17,CDC42,HNF4A,ADAMTS16,IFT88,PODXL,RAC1,HRAS,RCC2,TBC1D10A,IFT140,FSCN1,PALM
GO:2001057	reactive nitrogen species metabolic process	GO_REACTIVE_NITROGEN_SPECIES_METABOLIC_PROCESS	-0.320703966244887	-0.980810295724525	0.475926807111649	0.824262804714591	17	SLC7A2,CPS1,NQO1,DDAH2
NA	multicellular organism metabolic process	GO_MULTICELLULAR_ORGANISM_METABOLIC_PROCESS	-0.222149903184635	-0.986791814462377	0.476044828391315	0.824262804714591	84	MMP1,ADAMTS3,SERPINH1,COL6A2,ADAM15,PRTN3,MRC2,TNXB,MMP12,AKR1C3,MMP20,HIF1A,MMP26,COL7A1,CTSK,COL6A5,COL12A1,MMP27,MMP19,MMP14,COL11A2,ACACA,COL11A1,FURIN
GO:0048260	positive regulation of receptor mediated endocytosis	GO_POSITIVE_REGULATION_OF_RECEPTOR_MEDIATED_ENDOCYTOSIS	-0.250243482566897	-0.984024610304479	0.477503268563185	0.826362983025028	46	VTN,CCL19,NLGN1,ANGPT1,TOR1A,CCL21,DAB2,MAGI2,PICK1,SCYL2
GO:0046928	regulation of neurotransmitter secretion	GO_REGULATION_OF_NEUROTRANSMITTER_SECRETION	0.261478614991773	0.984313271915924	0.478072940117064	0.826923698064768	44	DRD4,LRRK2,CAMK2A,CPLX3,STX1A,SNCG,RAB3GAP1,PPP1R9A,GRIK5,SYT12,SLC30A1,ATP2A2,PFN2,RAB3A,RIMS3,MEF2C
GO:0035305	negative regulation of dephosphorylation	GO_NEGATIVE_REGULATION_OF_DEPHOSPHORYLATION	0.239209857329687	0.98536722494336	0.47852652709056	0.827056645626637	68	CEP192,PPP1R16B,ROCK2,AKAP1,ELL,WNK1,PCDH11X,SYTL2,DLG2,PPP1R37,IKBKB,TNF,SPOCD1,BAG4,CD2BP2,UBN1,CCDC8,SFI1,PCIF1,FKBP15,ZCCHC9,MPHOSPH10,PPP1R11,PPP1R26,PPP1R15A
NA	regulation of establishment of protein localization to plasma membrane	GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE	-0.252606850628144	-0.983347194980698	0.478741821615667	0.827056645626637	44	EZR,ITGA3,PRKCI,ARHGEF16,ANXA13,RHOQ,PPP2R5A,RHOG,EPHA2,TMEM59,PDPK1,DLG1,WNK3
GO:0050678	regulation of epithelial cell proliferation	GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION	-0.187743729765694	-0.990360184545198	0.479092058141984	0.827056645626637	264	TGM1,GDF5,CDKN2B,PRKCA,SCG2,SFN,EPGN,SULF1,OSR1,KDR,TGFBR1,IFT57,PRKD1,BMP4,WNT5A,SFRP2,BMP2,FGF7,HTRA1,ANGPT1,GATA3,FGFR2,SOX11,TACR1,XBP1,MEN1,WNT10B,CTNNB1,FGF18,MMP12,SULF2,ERRFI1,NR4A3,EGFR,TNMD,HIF1A,BMP5,CDH3,LEP
GO:1904353	regulation of telomere capping	GO_REGULATION_OF_TELOMERE_CAPPING	0.316771002657416	0.983290458764238	0.479293116210215	0.827056645626637	20	SMG6,MAP3K4,MAPKAPK5,MAPK1,PRKCQ,PKIB,MAP2K7,NEK7,ATM,MAPK3,TNKS
GO:0061213	positive regulation of mesonephros development	GO_POSITIVE_REGULATION_OF_MESONEPHROS_DEVELOPMENT	-0.301962874474907	-0.977594247935684	0.479582705864379	0.827056645626637	21	PAX8,WT1,WNT2B,GATA3
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS	-0.325496647211437	-0.978035517522967	0.480247635127822	0.827056645626637	16	SKIL,ATF3,BMPR1B,STK3,THBS1
GO:0031468	nuclear envelope reassembly	GO_NUCLEAR_ENVELOPE_REASSEMBLY	-0.331829166320819	-0.977557849913566	0.480336774668312	0.827056645626637	15	REEP3,UBXN2A
GO:1901606	alpha amino acid catabolic process	GO_ALPHA_AMINO_ACID_CATABOLIC_PROCESS	0.230921722697484	0.985775253970188	0.480641554266546	0.827056645626637	83	IVD,HIBCH,MCCC2,DDO,AMT,AUH,ALDH7A1,PPAT,OTC,DLD,THNSL2,OGDH,HAAO,ASRGL1
GO:0034198	cellular response to amino acid starvation	GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STARVATION	-0.29175099352096	-0.979468037497745	0.480721993157295	0.827056645626637	24	DAP,SLC38A2,ATF3,SH3GLB1,CDKN1A,EIF2AK3,EIF2AK4,RRAGC
GO:0044275	cellular carbohydrate catabolic process	GO_CELLULAR_CARBOHYDRATE_CATABOLIC_PROCESS	0.284597430357346	0.98085894369387	0.4807653721978	0.827056645626637	30	PYGB,PYGM,CALM3,PHKG1,PFKM,CALM1,PHKA2,PHKB
GO:0046513	ceramide biosynthetic process	GO_CERAMIDE_BIOSYNTHETIC_PROCESS	0.265176514396265	0.982526101334133	0.480852601156069	0.827056645626637	41	AGK,CERS4,ST6GALNAC4,ST8SIA6,ST3GAL6,ST3GAL3,CLN8,ST3GAL2,SMPD4,ST6GALNAC3,CERS6,P2RX7
GO:0002825	regulation of t helper 1 type immune response	GO_REGULATION_OF_T_HELPER_1_TYPE_IMMUNE_RESPONSE	-0.301499750825281	-0.976094901313205	0.481917981623344	0.828465743689569	21	CCL19,IL27,ANXA1,RIPK2
GO:0019730	antimicrobial humoral response	GO_ANTIMICROBIAL_HUMORAL_RESPONSE	-0.25339828562294	-0.980981259577481	0.482361670076669	0.828655514381978	43	SLPI,DEFA5,DEFA6,HIST1H2BE,HIST1H2BK,KLK3,SEMG2
GO:0019433	triglyceride catabolic process	GO_TRIGLYCERIDE_CATABOLIC_PROCESS	-0.30135893259351	-0.975639007211576	0.482769156899976	0.828655514381978	21	LIPC,LPL,FABP2,CPS1,FABP4,LIPE,FABP1
GO:0009311	oligosaccharide metabolic process	GO_OLIGOSACCHARIDE_METABOLIC_PROCESS	0.243622285257042	0.981760588782056	0.482994523509916	0.828655514381978	61	MGAT4B,EDEM2,ST6GALNAC4,ST8SIA6,ST3GAL6,MANBA,ST3GAL3,ST3GAL2,NEU3,B3GALT2,ST6GALNAC3,GANC,MGAT4C,GNPTAB,MAN2A2,ST6GAL1,MAN2C1,B3GALNT1,ST3GAL4,B3GALT1
GO:0015893	drug transport	GO_DRUG_TRANSPORT	0.300577186518742	0.979439169628251	0.483090100356578	0.828655514381978	24	NR1I2,SLC17A3,ABCA8,ABCC2,ABCB4,ATP8B1,ABCG2,SLC22A2,SLC15A2
GO:0070861	regulation of protein exit from endoplasmic reticulum	GO_REGULATION_OF_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM	-0.314134770927441	-0.975531038831159	0.483259291364178	0.828655514381978	18	BRSK2,BCAP31,SORL1,ERLEC1,GCC2
GO:0051310	metaphase plate congression	GO_METAPHASE_PLATE_CONGRESSION	-0.260200636516199	-0.9787355563183	0.484190254389108	0.829495729892595	38	KIF2C,KIF18A,CEP55,SPICE1,CCNB1,CDCA8,CHMP5,ZW10
GO:0050803	regulation of synapse structure or activity	GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY	-0.19221871840484	-0.988933954007609	0.484242159607531	0.829495729892595	216	LRRN1,SLITRK2,SORCS3,DRD5,IGSF9,SNAP25,NLGN1,AGRN,RARA,FLRT3,WNT5A,SLITRK4,KRAS,LRRC4B,EFNA5,CBLN2,TPBG,SNCA,FLRT2,SRPX2,NRGN,ATP2B2,GRIN2A,YWHAH,FLRT1,STAR,CLSTN3,ROBO2,BAIAP2,NETO1,CHRNB2,CDK5,UNC13B,MAGI2,AMIGO2,EIF2AK4,ITPR3,SHISA8,KCNB1,PICK1,CDC20,STXBP1,SLC8A3
GO:0006144	purine nucleobase metabolic process	GO_PURINE_NUCLEOBASE_METABOLIC_PROCESS	-0.30500433627317	-0.974660450188735	0.484661241895479	0.829541759972954	20	SHMT1,AOX1,GART,PAICS
GO:2001222	regulation of neuron migration	GO_REGULATION_OF_NEURON_MIGRATION	-0.28783410775184	-0.976369211086078	0.484761925688295	0.829541759972954	25	NKX6-1,UNC5D,SEMA3A,FLRT2,PLXNB2,STAT3
GO:0048486	parasympathetic nervous system development	GO_PARASYMPATHETIC_NERVOUS_SYSTEM_DEVELOPMENT	-0.318299507145241	-0.973456728295361	0.48646018081931	0.831497746405915	17	SEMA3F,SEMA3A,GDNF,NAV2,PLXNA4
GO:0061180	mammary gland epithelium development	GO_MAMMARY_GLAND_EPITHELIUM_DEVELOPMENT	-0.244329608337979	-0.978545778702316	0.486884875846501	0.831497746405915	50	TNFSF11,AREG,WNT5A,CEBPB,FGFR2,FOXF1,CSF1,MSX2,WNT7B,HIF1A
GO:0040018	positive regulation of multicellular organism growth	GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISM_GROWTH	-0.272225473617007	-0.975092981851003	0.486930710614921	0.831497746405915	31	PPIB,EZR,POU3F2,SPTBN4,CSF1,SLC6A3
GO:0032731	positive regulation of interleukin 1 beta production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION	-0.274571771198062	-0.975707581532078	0.487261780915912	0.831497746405915	30	CCL3,GSDMD,CCL19,WNT5A,PYCARD,NLRP3,NLRP12,IFNAR1,NOD1
GO:0042181	ketone biosynthetic process	GO_KETONE_BIOSYNTHETIC_PROCESS	0.299790957987304	0.976877221967192	0.487299194941734	0.831497746405915	24	COQ9,NDUFA9,SCP2,ADM,COQ2,HSD17B3,GPI,COQ5,COQ7,STARD3,HSD17B1,PDSS2,LHB,COQ4
GO:1905114	cell surface receptor signaling pathway involved in cell cell signaling	GO_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY_INVOLVED_IN_CELL_CELL_SIGNALING	-0.23064046219677	-0.980347230904683	0.487433464475816	0.831497746405915	67	ANXA9,BMP4,BMP2,GABRA4,TSPO,SNCA,OPRM1,GRIN2A,SLC17A7,GLRA4,CHRNB2,CDK5,GRID2,CHRNG,SEZ6,GRIN3B,GRIK2
GO:0060117	auditory receptor cell development	GO_AUDITORY_RECEPTOR_CELL_DEVELOPMENT	-0.31794397169654	-0.972369392729595	0.487844443483151	0.831497746405915	17	PDZD7,LRTOMT,ATP2B2
GO:0015672	monovalent inorganic cation transport	GO_MONOVALENT_INORGANIC_CATION_TRANSPORT	-0.179639019960557	-0.990860396161054	0.487881179189448	0.831497746405915	396	SCN4A,COX6B2,SLC34A1,SLC24A3,SCNN1A,SCN3B,ATP6V1C2,SLC5A9,KCNH5,P2RX1,SLC36A2,KCNV2,SLC9A7,CNGB1,KCNT2,KCNS2,KCNMB2,AQP1,ATP6V1B1,KCNA3,SLC22A4,ANO6,SLC10A1,SLC4A4,SLC17A5,SGK1,KCNH1,SNCA,SLC38A2,SLC18A1,KCNG1,SLC22A3,ABCB11,ATP6AP1L,CNGA4,HTR3A,ATP6V0D1,ATP6V1H,UCP1,SLC17A2,FXYD4,KCNK16,SLC17A7,SLC6A3,SNAP23,SLC12A8,SLC35A3,KCNAB2,SLC18A2,KCNN1,SLC2A10,SLC5A2,KCNK15,RHCE,KCNK1,SCNN1G,SLC38A1,KCNG3,KCNB1,SCNN1B,SLC13A5,KCNIP1,SLC9B2,KCNA1,SLC38A8,KCNN4,KCNQ4,SLC44A5,SLC8A3,KCNJ16,ADCYAP1,ATP6V1A,ATP4B,SLC47A1,CYB5A,PKD2,SHROOM2,OAZ3,EDN1,SLC9A3,FCER1A,SLC3A2,SLC23A2,ATP4A,KCNQ5,KCNK2,SLC17A6,SLC44A1,SLC38A11,SLC13A4,SLC5A11,PSEN1,ATP5L2,SLC18A3,SLC20A1,ATP1B1,HCN2
GO:0014003	oligodendrocyte development	GO_OLIGODENDROCYTE_DEVELOPMENT	0.283411136505676	0.976770407360993	0.488335187786148	0.831850324943408	30	EIF2B5,PRDM8,PTEN,MED12,SHH,HDAC11,EIF2B4,NKX2-2,PLP1,ASCL1,CNTN2
GO:1900180	regulation of protein localization to nucleus	GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS	0.201150042943308	0.985202123666861	0.490901911750189	0.835263270547945	205	PIK3R1,RBCK1,FLCN,PYDC2,HNRNPM,AKAP1,PIN1,MCRS1,KAT7,C8orf4,SUFU,PKIA,GSK3B,AKAP6,JAK2,DDX58,CDK5RAP3,CSF3,CABP1,RGS20,MBTPS1,AGTR2,UBR5,PDE2A,SHH,EP300,TCP1,ERBB4,PPP3R1,MTOR,IL18R1,TNF,SEMA5A,TMEM173,EMD,PARK7,CDK1,FAF1,CCT3,KANK1,MDFI,HYAL2,CD36,SMAD3,TPR,BAMBI,LITAF,NFKBIA,EGF,TLR4,TGFB3,FAM89B,MED1,CCT7,CCT4,EDA,PRKCQ,JUP,PIK3R2,RASSF5,PPM1B,SMO,SIN3A,OGG1,PLK1,HSP90AB1,SPPL3,NF1,PPP3CB,TRIM8,CDKN2A,RGS19
GO:0042454	ribonucleoside catabolic process	GO_RIBONUCLEOSIDE_CATABOLIC_PROCESS	0.302473666022185	0.975250313189889	0.490907755042063	0.835263270547945	23	CECR1,ENTPD4,ADA,AICDA,APOBEC3H,APOBEC1
GO:0035272	exocrine system development	GO_EXOCRINE_SYSTEM_DEVELOPMENT	-0.250717375377314	-0.975991851357714	0.49110776356319	0.835263270547945	44	SEMA3C,IGSF3,FGF7,FGFR2,SEMA3A,XBP1,EDAR,EGFR
GO:0001570	vasculogenesis	GO_VASCULOGENESIS	0.245887515484246	0.977097328582285	0.491331335616438	0.835263270547945	57	AMOT,TIE1,YAP1,QKI,TGFBR2,TNNI3,SHH,RASIP1,ZMIZ1,TBX5,NKX2-5,SOX17,VEGFA,ENG,HEY2,GJC1
GO:0006949	syncytium formation	GO_SYNCYTIUM_FORMATION	-0.28367367997925	-0.972296871785047	0.492004487165387	0.835985413325943	26	CDON,KCNH1,FER1L5,NPHS1,SH3PXD2A,CAPN2,MYOD1
GO:0060612	adipose tissue development	GO_ADIPOSE_TISSUE_DEVELOPMENT	0.282637600238782	0.974104431197041	0.492293380515477	0.836054247636274	30	LRP5,PPARD,EBF2,DYRK1B,ACAT1,HMGCS2,ATF2,FTO
GO:0035924	cellular response to vascular endothelial growth factor stimulus	GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS	-0.273489731130501	-0.971862485975335	0.493570021470152	0.837195219518832	30	KDR,PRKD1,GAS1,ITGB1BP1,XBP1
GO:0042036	negative regulation of cytokine biosynthetic process	GO_NEGATIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS	0.290028266731104	0.973483429259725	0.494185301173928	0.837195219518832	27	TRIB2,GHSR,INPP5D,TIA1,SIGIRR,ASB1,NFKB1,LILRB1,FOXJ1
GO:0097581	lamellipodium organization	GO_LAMELLIPODIUM_ORGANIZATION	0.274472728180385	0.974388426867531	0.49423384749709	0.837195219518832	34	ABLIM1,NUP85,ABLIM3,ARHGEF6,SPATA13,CDH13,S1PR1,CCDC88A,PLEKHO1,ARHGEF4,VCL,GOLPH3,ABI1,PARVB
GO:0060079	excitatory postsynaptic potential	GO_EXCITATORY_POSTSYNAPTIC_POTENTIAL	0.289991840202339	0.973361163169811	0.494295185246232	0.837195219518832	27	NLGN3,ADRB2,LRRK2,GRIN2C,RAB3GAP1,PPP1R9A,GRIK5
GO:0098543	detection of other organism	GO_DETECTION_OF_OTHER_ORGANISM	-0.307644109401193	-0.96894174705664	0.49430904904644	0.837195219518832	19	HLA-DRB5,PGLYRP1,NOD1,TLR2,HLA-DRB1,PGLYRP2,PGLYRP3,TLR6
GO:0043954	cellular component maintenance	GO_CELLULAR_COMPONENT_MAINTENANCE	0.321928971320713	0.971257012038746	0.494457544980225	0.837195219518832	18	KIFC3,MTHFR,PKP2,TANC1,RAB3A,ITPKA,NLGN2,MTMR2,MYOCD
GO:0045746	negative regulation of notch signaling pathway	GO_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY	-0.286006459792732	-0.970169601144383	0.494891344949573	0.837508429914661	25	BEND6,DLX1,GDPD5,CHAC1
GO:0019400	alditol metabolic process	GO_ALDITOL_METABOLIC_PROCESS	-0.316225260442755	-0.967113050836388	0.495263226197171	0.837509131390242	17	GK,ANGPTL3,DGAT2,LEP,PCK1
GO:0071871	response to epinephrine	GO_RESPONSE_TO_EPINEPHRINE	0.337952524089893	0.971095586349078	0.495696946039889	0.837509131390242	15	PRKACA,RYR2,GSK3B
GO:0000717	nucleotide excision repair dna duplex unwinding	GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DUPLEX_UNWINDING	-0.298701907756347	-0.967036982204532	0.495798686134573	0.837509131390242	21	CETN2,UBA52,GTF2H2,DDB2,GTF2H1,XPC,UBB
GO:0032272	negative regulation of protein polymerization	GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION	0.24972961665909	0.974298210795933	0.496374541222809	0.837509131390242	52	SPTB,TBCD,LMOD1,LMOD3,INPP5J,ADD1,VDAC2,CAPZB,TMOD1,ARFGEF1,FHOD3,RDX,MKKS,KANK1,PFN2,CAPG,SPTBN1,MAPRE1
GO:1902932	positive regulation of alcohol biosynthetic process	GO_POSITIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS	0.305072349347802	0.971723884276163	0.496639723076357	0.837509131390242	22	P2RY1,ADCYAP1R1,FGF1,TNF,PTAFR,PTH1R,POR,HRH1,SREBF1,IL1B
GO:1901524	regulation of mitophagy	GO_REGULATION_OF_MITOPHAGY	0.26399925264707	0.972734346879505	0.496964879317821	0.837509131390242	40	PARL,FBXW7,ADRB2,PINK1,KAT2A,PARK7,HDAC6,VDAC1,USP36,MAP1LC3B,AMBRA1,WBP11
NA	macromitophagy	GO_MACROMITOPHAGY	-0.206807712225828	-0.980537721298582	0.497179125528914	0.837509131390242	124	GDF5,PLOD2,ALPK1,LENG9,SNRPF,ANXA5,TMEM39A,FANCF,SLC22A3,NEFM,CLVS1,HCAR1,LARP1B,FGFBP1,MSTN,PHYHIP,ZCCHC17,HK2,HPR,SLC1A4,LMCD1,BOC,KRT15,C5,YIPF1,FABP1,ZNF593,SNRPB
GO:0006885	regulation of ph	GO_REGULATION_OF_PH	-0.221424355138597	-0.978799602307327	0.497279118107294	0.837509131390242	82	SLC26A9,CFTR,ATP6V1C2,SLC9A7,ATP6V1B1,SLC4A4,RAB38,ATP6V0D1,ATP6V1H,SLC17A7
GO:0032753	positive regulation of interleukin 4 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_4_PRODUCTION	-0.29491190480428	-0.966854281474698	0.497406491431573	0.837509131390242	22	RARA,GATA3,CEBPB,IRF4,NLRP3
GO:0045646	regulation of erythrocyte differentiation	GO_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION	-0.264687486336716	-0.97018328066978	0.497534757695554	0.837509131390242	34	KDM1A,GAS2L1,HIF1A,HMGB2,ACVR1B,MAFB,SENP1,FOXO3,MAPK11,INHBA
GO:2000677	regulation of transcription regulatory region dna binding	GO_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING	-0.262658089847555	-0.969802982126199	0.497799608819346	0.837509131390242	35	ZBTB7C,GATA3,SOX11,KLF4,CTNNB1,MSX2
GO:0061298	retina vasculature development in camera type eye	GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE	0.331397585375309	0.968322211686733	0.498429513985689	0.837509131390242	16	LRP5,NRP1
GO:0071480	cellular response to gamma radiation	GO_CELLULAR_RESPONSE_TO_GAMMA_RADIATION	0.316540340170689	0.968650573697852	0.498888147653992	0.837509131390242	19	YAP1,TLK2,CYBA,GTF2H5,ELK1,TSPYL5,NOX4,WRN,ATM,ATR,RAD51,TMEM109,XRCC6
GO:0034508	centromere complex assembly	GO_CENTROMERE_COMPLEX_ASSEMBLY	0.272112886031445	0.972247261731915	0.498927467733139	0.837509131390242	35	CENPK,POGZ,NPM1,CENPA,HELLS,HIST1H4F,CENPN,CENPI,HIST1H4A,CENPO,CENPV,CENPT
GO:0045912	negative regulation of carbohydrate metabolic process	GO_NEGATIVE_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS	0.268223382208061	0.971521444024348	0.49904955012039	0.837509131390242	37	PPARA,GRB10,HDAC4,GSK3B,ACER2,GCK,COX11,SERPINA12,PASK,DDIT4,CBFA2T3
GO:0046488	phosphatidylinositol metabolic process	GO_PHOSPHATIDYLINOSITOL_METABOLIC_PROCESS	0.203020713234933	0.982461727519692	0.499156160031768	0.837509131390242	187	PIK3C2B,PIK3R1,MTMR1,PDGFB,PLA2G4C,DRD2,PLA2G5,SMG1,INPP5J,PIP5K1B,ARF1,INPPL1,IMPA2,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,INPP5D,PIK3C3,INPP1,PIP4K2C,IRS1,IP6K3,PIKFYVE,PI4K2A,GPAA1,PIP4K2B,IP6K2,FGFR1,ERBB4,PIK3R5,PIK3C2G,MPPE1,PLA2G4E,EFR3B,PIGM,FAM126A,CD80,PIP5K1C,GAB1,FGF6,TTC7B,VAC14,FGF8,INPP5A,MTMR14,EGF,SLC27A1,SACM1L,INPP5F,DPM2,PLA2G4D,PIGS,TMEM150A,MTMR2,EFR3A,PIK3R6,CDIPT,PIK3R2,PIK3CB,EREG,GRB2,SYNJ1,PIK3CG,PIGO,GPLD1,PIGG,PIK3C2A
GO:0051385	response to mineralocorticoid	GO_RESPONSE_TO_MINERALOCORTICOID	-0.26440423289328	-0.9691450458865	0.499444765246746	0.837509131390242	34	CTGF,KRAS,CDKN1A,STAR,HTR1B,SLC18A2,PTGS1,BAX,EDN1,JUNB,ATP2B1,NTS,RAN
GO:0006221	pyrimidine nucleotide biosynthetic process	GO_PYRIMIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS	-0.288230588916255	-0.967649315827751	0.499451706290025	0.837509131390242	24	DTYMK,SHMT1,DUT,NME9
GO:0014068	positive regulation of phosphatidylinositol 3 kinase signaling	GO_POSITIVE_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING	0.244651526592644	0.972185808606321	0.500017836757991	0.837509131390242	57	AGT,PPARD,PDGFB,FLT1,NKX3-1,JAK2,CSF3,GH1,FGFR1,ERBB4,TEK,SELP,SOX9,SERPINA12
GO:0014821	phasic smooth muscle contraction	GO_PHASIC_SMOOTH_MUSCLE_CONTRACTION	-0.320946846065788	-0.964364509983463	0.500140701777172	0.837509131390242	16	SSTR2,GDNF,EDNRB,EDN1,DLG1
GO:0046823	negative regulation of nucleocytoplasmic transport	GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT	0.237168837824493	0.974419237210384	0.500264121707283	0.837509131390242	67	PYDC2,AKAP1,RANGAP1,SP100,SUFU,PKIA,GSK3B,CABP1,PDE2A,MTOR,EMD,PARK7,FAF1,MDFI,CD36,TPR,LITAF,NFKBIA,FAM89B
GO:0030148	sphingolipid biosynthetic process	GO_SPHINGOLIPID_BIOSYNTHETIC_PROCESS	-0.228521761446183	-0.974279867585331	0.500636412024716	0.837509131390242	68	GAL3ST1,P2RX1,ALDH3B1,DEGS2,PRKD1,SGPP2,ALDH3A2,SMPD2,ALOX12B,SGPL1,CERS2,SGMS2,KDSR,ALDH3B2,ST3GAL5
GO:0090066	regulation of anatomical structure size	GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE	0.18524884259065	0.986940973567023	0.500722032752635	0.837509131390242	444	SEMA6A,P2RY1,AMOT,SHANK3,XK,SPTB,AGT,PTPRM,PPARD,TRPM4,CDKL5,NRP1,ADRB1,SERPINF2,PRR16,SSH2,LPAR3,SEMA6C,BARHL2,VIP,NPY1R,PAFAH1B1,RAB21,ALS2,ADRB2,TRPV2,P2RY2,LRRK2,TSC1,HRH2,MEGF8,CLCN6,ATP1A2,ADRA2C,CCL24,MACF1,LMOD1,LMOD3,GJA1,ARF1,HMGCR,GUCY1A3,ADD1,GSK3B,CAV3,PTEN,SPIRE1,CSF3,UCN,CLN8,HP1BP3,DOCK4,ACTR3B,FAM21C,PPP1R9A,SLC8A1,GOLGA4,LIMK1,AGTR2,WDTC1,LATS1,SLC26A5,CX3CL1,EP300,CAPZB,WASL,TMOD1,EPHA7,ESR2,GJA5,MTOR,KCNA5,CCR2,CREB1,SEMA5A,ACE2,SOD2,KCNMA1,VEGFA,BAG4,ARFGEF1,JMY,P2RX7,FHOD3,SOD1,SSH1,ADORA2B,RDX,C15orf62,AKT1S1,MKKS,PTAFR,KANK1,CD38,L1CAM,SLC12A7,MLST8,CFL2,AQP7,BCL11A,PRKCE,PRKG1,PLXNA3,PFN2,ARF6,PLXND1,SCPEP1,NTRK3
GO:0043949	regulation of camp mediated signaling	GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING	0.300489284050775	0.968852172272182	0.500863304066713	0.837509131390242	23	GNAS,ADRB1,CXCL11,RAPGEF2,CXCR3,CXCL9,UBE2B,CDC34,CRTC3
GO:0008361	regulation of cell size	GO_REGULATION_OF_CELL_SIZE	0.206113701771343	0.980139132348875	0.502012996775864	0.839014770182502	164	SEMA6A,AMOT,SHANK3,XK,CDKL5,NRP1,PRR16,LPAR3,SEMA6C,BARHL2,PAFAH1B1,RAB21,TRPV2,TSC1,MEGF8,CLCN6,MACF1,ADD1,GSK3B,CAV3,PTEN,UCN,CLN8,GOLGA4,LIMK1,WDTC1,SLC26A5,EP300,EPHA7,MTOR,CCR2,CREB1,SEMA5A,KCNMA1,VEGFA
GO:0045930	negative regulation of mitotic cell cycle	GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE	-0.195401455579995	-0.981881287573484	0.502271465347534	0.839030150054491	182	TOM1L1,CDKN2B,SFN,PTPN3,BMP4,SLFN11,GAS1,WNT9A,MUC1,CNOT6,BTG3,CTNNB1,TP73,CDKN1A,NLE1,PTTG3P,UBA52,TOP2A,RPA2,CCNB1,FZD3,TRIM35,RPS27L,CCNA2,TEX14,CHEK2,XPC,TIMP2,BAX,E2F4,TRIAP1,PSMG2,PKD2,KNTC1,ZW10,BTG2,MDM2,ANGEL2,HNF4A,UBB,DLG1,CNOT7,RPS6,ABL1,NAE1,NBN,PCNA,SYF2,BCL2,BTG4
GO:0061008	hepaticobiliary system development	GO_HEPATICOBILIARY_SYSTEM_DEVELOPMENT	0.215065577366286	0.977685865972306	0.502528132927016	0.839042507654929	120	KLKB1,TK1,PHF2,JARID2,STAT5B,ADRB2,HLX,OTC,CCND1,PCSK9,FPGS,LBP,AK4,DDX39B,E2F8,ACAT1,EP300,ADA,TET2,IGF2R,HMGCS2,RXRA,SOX17,HMGCS1,RHBDD3,SOX9,POU2F1,SMAD3,ASNS,PSMB9,CAD,ARF6,PROX1,MED1,CYP1A1
GO:0032878	regulation of establishment or maintenance of cell polarity	GO_REGULATION_OF_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY	0.311459122152648	0.966801823836746	0.503090303478904	0.839228061466877	20	ROCK2,CDH5,TEK,ARFGEF1,KANK1,BCAS3
GO:0045662	negative regulation of myoblast differentiation	GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION	0.29996275351749	0.967154506904337	0.503140957349105	0.839228061466877	23	PPARD,ANKRD2,PRICKLE1,ZFHX3,TNF,SOX9,TBX3,GDF3
GO:0000819	sister chromatid segregation	GO_SISTER_CHROMATID_SEGREGATION	0.207449254043625	0.978811304911186	0.503638009656652	0.839228061466877	155	GSG2,NDE1,SPAG5,CENPK,FBXW7,POGZ,CLASP1,CENPA,PAFAH1B1,AKAP8,VPS4A,RANGAP1,NCAPH,CLIP1,NUP85,MAD2L1,CHMP7,TTN,SMC1A,LATS1,SMC2,MAU2,KIFC1,INCENP,CENPN,NAA50,NCAPD3,DLGAP5,KIF25,CEP57L1,CENPI,CHMP6,KLHL22,ZWILCH,MAD1L1,MRE11A,CKAP5,ESPL1,AKAP8L,DIS3L2,TOP2B,MAPRE1,CHMP1B,PAPD7,CLASP2,PHF13,KPNB1,CENPO,CHMP4B,CENPT,SKA2,PLK1
GO:0046364	monosaccharide biosynthetic process	GO_MONOSACCHARIDE_BIOSYNTHETIC_PROCESS	-0.239390514687323	-0.970394749494478	0.503701180744777	0.839228061466877	53	PCK2,RBP4,ALDOB,GPD1,PC,ATF3,BPGM,FBP1,PCK1
GO:0051973	positive regulation of telomerase activity	GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY	0.285474377066175	0.967310109434255	0.503885891926488	0.839228061466877	28	HMBOX1,PARM1,OBFC1,MAP3K4,MAPKAPK5,TCP1,ACD,MAPK1,WRAP53,CCT4,PRKCQ,PKIB,MAP2K7
GO:0002548	monocyte chemotaxis	GO_MONOCYTE_CHEMOTAXIS	-0.259694009449981	-0.965273909076637	0.504957996301	0.840199195735528	36	CCL3,TNFSF11,CCL19,RPS19,ANXA1,S100A12,CCL21
GO:0051055	negative regulation of lipid biosynthetic process	GO_NEGATIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS	0.262847972194132	0.968492327145604	0.504968203497615	0.840199195735528	40	FBXW7,PDGFB,APOC3,REST,CYP27B1,DKK3,WDTC1,INSIG1,SOD1,TRIB3,SERPINA12,NFKB1,ACADVL,PROX1,SLC27A1
GO:0071675	regulation of mononuclear cell migration	GO_REGULATION_OF_MONONUCLEAR_CELL_MIGRATION	-0.319689789221308	-0.960587370489156	0.505877005000325	0.840907273090486	16	CSF1,BMP5,C5AR1,RARRES2,CMKLR1,THBS1
GO:0021854	hypothalamus development	GO_HYPOTHALAMUS_DEVELOPMENT	-0.290075963757174	-0.962130812628588	0.505904302019315	0.840907273090486	23	HAP1,SOX3,SEMA3A,POU3F2
GO:0006182	cgmp biosynthetic process	GO_CGMP_BIOSYNTHETIC_PROCESS	0.335140476325699	0.963015258558169	0.506143236863139	0.840907273090486	15	GUCY1A2,GUCY1B3,GUCY1A3,NPR2,GUCY2C
GO:0032648	regulation of interferon beta production	GO_REGULATION_OF_INTERFERON_BETA_PRODUCTION	-0.249709210466809	-0.966699735989266	0.50736335634148	0.842518528586789	43	POLR3D,TRAF3IP1,POLR3G,PYCARD,RIPK2,IRF7,TRIM38,TLR9,IFNAR1,HMGB2,TLR2
GO:0044320	cellular response to leptin stimulus	GO_CELLULAR_RESPONSE_TO_LEPTIN_STIMULUS	-0.325176556854256	-0.9579594804316	0.508213752353743	0.843117834574987	15	STAT3,NR4A3,LEP,CCNA2
GO:0042594	response to starvation	GO_RESPONSE_TO_STARVATION	-0.201196907410745	-0.977387426415089	0.508290550001228	0.843117834574987	144	SSTR3,DAP,ALDOB,ULK2,SSTR2,WNT2B,SLC38A2,GAS2L1,ATF3,XBP1,AKR1C3,TBL2,SH3GLB1,CDKN1A,CPS1,EIF2AK3,PPM1D,USP33,SLC18A2,PPARG,PCK1,EIF2AK4,PICK1,FOXA3,MYOD1,KIAA1324,ADCYAP1,RRAGC,CPEB4,CARTPT,WNT9B,GCGR,BHLHA15,SLC2A1,NFE2L2,IFI16,SIRT1,SLC39A4
GO:0019748	secondary metabolic process	GO_SECONDARY_METABOLIC_PROCESS	-0.249560834959616	-0.966125329609289	0.508554983474605	0.843117834574987	43	CYP11A1,PMEL,DDC,AKR1C3,STAR,BDH2,CYP1A2,BCL2,AKR1C1,CYP1B1,SLC45A2,ASIP,CYP2W1,AKR1C2,DCT,FMO2
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	0.245127934559483	0.967239722039913	0.508743754461099	0.843117834574987	55	PIK3R1,MAPKAPK2,HDAC2,ARFGEF2,ZBTB20,SPN,ARHGEF2,JAK2,LBP,NFATC4,CCR2,CYBA,HSPB1,PTAFR,HMGB1,CD36
GO:0005996	monosaccharide metabolic process	GO_MONOSACCHARIDE_METABOLIC_PROCESS	0.203683180122827	0.977890470700772	0.508976660682226	0.843117834574987	176	UGT2A3,LRP5,BAD,PPARD,AKT2,DLAT,NPY1R,PGM5,UGT3A1,CRYL1,PGAM2,PGAM1,FUT5,SLC25A11,UGT3A2,INPPL1,PDHA1,PFKM,GCK,MDH2,MDH1,WDTC1,PFKFB4,GOT2,OAS1,PFKP,TNF,ALDOC,MPI,FUT4,PDHB,ALDOA,HK3,ENO2,GALK1,MAN2A2,SERPINA12,GOT1,CRTC2,UGT2B11,FUCA2,MAN2C1,SLC25A12,FUCA1,SLC25A10,NISCH,GPI,TKT,SLC23A1,PDK3,USF1,IGFBP5,CYB5R3,ADPGK,ALDH1A1,PGK1,GALT
GO:0045444	fat cell differentiation	GO_FAT_CELL_DIFFERENTIATION	-0.214369468564655	-0.974057239462171	0.509591444763237	0.843721004954774	96	ID4,RETN,CEBPB,BBS7,SOCS1,GDF10,KLF4,UCP1,CEBPA,NR4A3,PRLH,NOC3L,ADIPOQ,FABP4,PPARG,RARRES2,OSBPL11,OSBPL8,PIAS1,LAMB3,SIRT1,RGS2,ZNF516,STEAP4,FBXO9,SNAI2,NR4A2,ALOXE3,FGF10,ARL4A,PSMB8,ADIG,GPX1,PRDM16
GO:0010596	negative regulation of endothelial cell migration	GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.269979932469402	0.964626313344128	0.510743501181603	0.845212696645662	35	PTPRM,CSNK2B,BMP10,SP100,STARD13,AGTR2,DLL4
GO:0045668	negative regulation of osteoblast differentiation	GO_NEGATIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION	0.266084062878492	0.963772698977653	0.511704111374622	0.845617909184672	37	LRP5,TRPM4,HAND2,HDAC4,SUFU,FGFR1,TNF,PTCH1,LIMD1,SMAD3
GO:0045786	negative regulation of cell cycle	GO_NEGATIVE_REGULATION_OF_CELL_CYCLE	0.186233022776144	0.983006090389288	0.51203531598513	0.845617909184672	401	CUL4A,PPP2R5C,FOXN3,PRKACA,AURKAIP1,CDK5RAP1,RRAGB,FBXW7,NPM1,MFN2,CSNK2A1,RRAGD,ZAK,GAS2,VPS4A,AK1,TSC1,CCND1,STRADA,IRF6,TAOK3,TSC2,PRKAB2,MAD2L1,MACF1,ZFHX3,SOX2,PLAGL1,NKX3-1,KANK2,OSM,ZNF655,CGREF1,PTEN,CDK5RAP3,PRKAA2,STRADB,PTPRK,PRKAR1A,MLF1,NPR2,DDX39B,TFDP2,CNOT6L,RNF167,E2F8,SMC1A,EZH2,LATS1,CNOT4,PRCC,KHDRBS1,DGKZ,EP300,DST,FBXO31,NME6,INTS3,PPP1R13B,IRF1,MYO16,MTOR,CDKN1B,CDK1,RUNX3,ATF2,JMY,APC,ETS1,PRPF19,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,TBRG4,ATRX,CUL2,CLSPN,MCPH1,SMAD3,CUL5,HEXIM2,MLST8,GIGYF2,KLHL22,GAS2L2,FOXO4,TPR,TAF6,ZWILCH,PRKDC,PRKAG3,MAD1L1,LILRB1,GAS2L3,MRE11A,TOM1L2,CTDSP2,CHFR,ESPL1,RASSF1,CNOT1,MAD2L1BP,TIPIN,TSG101
GO:0071470	cellular response to osmotic stress	GO_CELLULAR_RESPONSE_TO_OSMOTIC_STRESS	0.309500291169514	0.96072140675346	0.512305699481865	0.845617909184672	20	DDX3X,CAPN3,ARHGEF2,SLC12A6,MYLK,SLC2A4
GO:0043486	histone exchange	GO_HISTONE_EXCHANGE	0.261742468068576	0.964418975335845	0.512375343257696	0.845617909184672	40	NASP,CENPK,NPM1,CENPA,HIST1H4F,PSME4,HIST1H2BA,CENPN,CENPI,ANP32E,HIST1H4A,CENPO,CENPT
GO:0010996	response to auditory stimulus	GO_RESPONSE_TO_AUDITORY_STIMULUS	0.298055298074295	0.961004396242355	0.512435252194997	0.845617909184672	23	SHANK3,NRXN1,DRD2,UCN,SLC26A5
GO:0097190	apoptotic signaling pathway	GO_APOPTOTIC_SIGNALING_PATHWAY	-0.185796417386024	-0.981109870208163	0.512495702536165	0.845617909184672	267	TNFRSF8,KRT8,EDA2R,PRKCA,PTGIS,BBC3,SFN,SSTR3,DAP,PHLDA3,SNW1,NUPR1,TNFRSF21,TNFRSF11B,LY96,KRT18,CEBPB,LGALS12,ZNF385C,CYCS,CRIP1,CHAC1,XBP1,SGPL1,TP73,BOK,BRSK2,PYCARD,RIPK1,MELK,CDKN1A,TRADD,RIPK3,TNFRSF1A,ZMAT3,CASP3,RPS27L,DAPK1,TNFRSF25,ARL6IP5,SST,FAS,CHEK2,GGCT,SART1,BAX,EPHA2,WWOX,PDPK1,ACVR1B,CUL1,MFF,SENP1,FOXO3,DNAJC10,IFI16,IFI6,IKBKE,INHBA,ABL1,SIRT1,PAWR,NBN
GO:0003254	regulation of membrane depolarization	GO_REGULATION_OF_MEMBRANE_DEPOLARIZATION	0.264197920141161	0.962886648706816	0.51326202435587	0.846467405184644	38	TRPM4,SCN5A,LRRK2,NEDD4L,GJA1,CAV3,GJA5,P2RX7,ANK3,SMAD7,FGF12,NPFF
GO:0007009	plasma membrane organization	GO_PLASMA_MEMBRANE_ORGANIZATION	0.200967102674825	0.976943567974839	0.514028586553732	0.846633014868065	194	ZFYVE27,P2RY1,DYSF,RILPL1,MTSS1L,AKT2,ANK2,KIF13A,TNIK,TMEM88,LRP6,RAPGEF6,ROCK2,SH3TC2,CLIP1,PPIL2,SYTL2,VAMP2,CDH2,PACSIN2,MACF1,SYT7,RAPGEF2,CAV3,PTEN,SGIP1,PKP2,GOLGA4,TUB,NFASC,MTSS1,PRKCZ,FNBP1L,RAMP3,IKBKB,TNF,FAT4,BAG4,PTCH1,CRB1,P2RX7,SOD1,TSPAN17,EFR3B,ANK3,RDX,FAM126A
GO:0035510	dna dealkylation	GO_DNA_DEALKYLATION	0.317413164444685	0.957632860489534	0.514102159422174	0.846633014868065	18	TET1,TET2,AICDA,FTO,ASCC1,APOBEC1
GO:0007041	lysosomal transport	GO_LYSOSOMAL_TRANSPORT	0.238051844986696	0.96575148038288	0.514781900580654	0.846633014868065	63	TRAK1,DENND3,KIF13A,ATG14,ADRB2,RAB12,PCSK9,VPS11,VPS39,GNPTAB,NPC1,CDX2,SORT1,GPRASP1
GO:0043403	skeletal muscle tissue regeneration	GO_SKELETAL_MUSCLE_TISSUE_REGENERATION	-0.291611966694221	-0.956035595493099	0.515024840778271	0.846633014868065	22	PAX7,ANXA1,WNT10B,MSTN,MYOD1,SOX15,EYS,WNT7A,ENO3,GPX1,IGF1
GO:0050732	negative regulation of peptidyl tyrosine phosphorylation	GO_NEGATIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION	-0.259936383653851	-0.959753724611773	0.515380512091038	0.846633014868065	35	GPRC5A,SFRP2,PTPN2,SOCS1,ERRFI1,MVP,SPINK1,HNF4A,PSEN1
GO:0016180	snrna processing	GO_SNRNA_PROCESSING	0.308868601853747	0.958760576778854	0.515470022205774	0.846633014868065	20	INTS2,EXOSC4,EXOSC7,TUT1,INTS3,EXOSC3
GO:0046460	neutral lipid biosynthetic process	GO_NEUTRAL_LIPID_BIOSYNTHETIC_PROCESS	0.28870539620295	0.960007203160789	0.515502667815692	0.846633014868065	26	LPIN1,MOGAT1,PLCE1,LPCAT4,AGPAT3,AGPAT1
GO:0051154	negative regulation of striated muscle cell differentiation	GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION	0.29405041505271	0.958171502247763	0.515531375215969	0.846633014868065	24	CFLAR,ANKRD2,PRICKLE1,HDAC4,CAV3,EZH2,NKX2-5
GO:0051928	positive regulation of calcium ion transport	GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT	0.220372488639484	0.969822154726229	0.515876580747702	0.846633014868065	99	PDGFB,ANK2,LPAR3,TRPV2,CALM3,CAMK2A,CACNA2D1,RYR2,S100A1,CAPN3,XCL1,LGALS3,ADCYAP1R1,CXCL11,AKAP6,CXCR3,UCN,CALM1,MYLK,HOMER1,P2RX7,CXCL9,PLCG1,ZP3,HTT,TRDN,SUMO1,JPH2
GO:0060330	regulation of response to interferon gamma	GO_REGULATION_OF_RESPONSE_TO_INTERFERON_GAMMA	-0.29469293692212	-0.954058079302983	0.51587769266025	0.846633014868065	21	PTPN2,SOCS1,PPARG,NR1H3,TXK,PIAS1,SOCS3,IFNGR2
GO:0006270	dna replication initiation	GO_DNA_REPLICATION_INITIATION	0.283073485566756	0.959174855255194	0.516467038493188	0.846822951338952	28	RPA4,ORC2,MCM4,MCM7,POLA2
GO:0071599	otic vesicle development	GO_OTIC_VESICLE_DEVELOPMENT	0.332675957717438	0.955933544493737	0.516496589155932	0.846822951338952	15	NRP1,EYA1,TCAP,SIX1,SOX9,FGF8,PROX1
GO:0036065	fucosylation	GO_FUCOSYLATION	-0.298600765213726	-0.954197437997251	0.51723162612593	0.847445025377801	20	FUT10,FUT8,FUT7,ADAMTSL1,THBS1,FUT1,FUT2
GO:0030856	regulation of epithelial cell differentiation	GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION	0.214546185123074	0.970836193086018	0.51758965434879	0.847445025377801	117	TRIM16,BAD,ZEB1,STAT5B,ATOH8,ROCK2,CCND1,YAP1,PROM1,ZEB2,CDH5,PRKX,GSK3B,CYP27B1,PRKCH,REG3G,EZH2,IKBKB,TNF,FAT4,PPP1R12A,PTCH1,NCOA3,PAX6,SOX9,HEY2,KIAA1109,LHX1,PTCH2,FOXJ1,TBX3,MED1,GDF3,XDH
GO:0061437	renal system vasculature development	GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT	0.32148663351193	0.955044092589661	0.517631304865347	0.847445025377801	17	NRP1,PDGFB,NOTCH3,TCF21
GO:0046822	regulation of nucleocytoplasmic transport	GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT	0.198989974586155	0.97519188261183	0.517967027542861	0.8475824087065	206	PRKACA,PIK3R1,RBCK1,PYDC2,NUDT4,AKAP1,RANGAP1,C8orf4,SP100,SUFU,PKIA,GSK3B,AKAP6,JAK2,DDX58,CSF3,CABP1,RGS20,IFI27,MBTPS1,AGTR2,UBR5,PDE2A,SHH,XPO4,KHDRBS1,EP300,ERBB4,PPP3R1,MTOR,IL18R1,NCBP2,TNF,SEMA5A,TMEM173,EMD,PARK7,CDK1,PPP1R12A,FAF1,KANK1,MDFI,HYAL2,CD36,SMAD3,TPR,AAAS,BAMBI,LITAF,RANBP3,NFKBIA,EGF,TLR4,TGFB3,FAM89B,MED1,AKAP8L,EDA,PRKCQ,JUP
GO:0001975	response to amphetamine	GO_RESPONSE_TO_AMPHETAMINE	0.277883399449383	0.95771918007744	0.51894277949036	0.848017995212259	30	HDAC9,HDAC2,DRD4,CALM3,DRD2,CALM1,SOD1,DPYSL2,TH,PPP1R1B,OXT,DRD3,GRIN1,DBH
GO:1900120	regulation of receptor binding	GO_REGULATION_OF_RECEPTOR_BINDING	0.32633476858486	0.953528989984951	0.518948053154911	0.848017995212259	16	PLCL1,NRP1,NKX3-1
GO:0048675	axon extension	GO_AXON_EXTENSION	-0.260967760962654	-0.956549030647068	0.518989028561276	0.848017995212259	34	SEMA3F,ULK2,FMOD,SEMA3A,SLIT3,EPYC,CDK5
GO:0050708	regulation of protein secretion	GO_REGULATION_OF_PROTEIN_SECRETION	-0.17962956032538	-0.982272513995673	0.519776202082872	0.848643051772408	364	ATP13A2,CFTR,PRKCA,RBP4,APOA2,CNR1,EZR,CCL3,GSDMD,CCL19,NKX6-1,SNAP25,ARL2BP,WNT5A,TNFRSF21,ANXA4,ANGPT1,GATA3,EFNA5,HLA-DRB5,RHBDF1,ANXA5,CIDEA,SYBU,OPRM1,ANXA1,SOCS1,XBP1,DPH3,SLC25A6,BRSK2,PYCARD,LPL,SERP1,ACVR1C,HIF1A,SAA1,HCAR2,DNAJC1,LEP,SEC24A,IL17RC,TLR10,NNAT,NOV,CLEC5A,RAPGEF3,SLC16A1,IL17F,NR1H3,ITPR3,KCNB1,C5,CLEC4E,SLC30A8,NLRP3,IL5,NLRP12,TLR9,CD34,KCNN4,STXBP5L,IFNAR1,ADAM9,F2R,CARTPT,ABAT,TLR2,SLC2A2,MIF,SLC2A1,NDUFAF2,VTCN1,HLA-DRB1,GPAM,LLGL1,IL17RB,MAPK11,HNF4A,PTGER4
NA	establishment of localization by movement along microtubule	GO_ESTABLISHMENT_OF_LOCALIZATION_BY_MOVEMENT_ALONG_MICROTUBULE	0.225118240453928	0.966928740297407	0.519875808899199	0.848643051772408	86	RHOT2,NDE1,FYCO1,KIF13A,BBS12,PAFAH1B1,APP,RAB6A,RAB21,KIF5B,KIF1A,PEX14,IFT27,PRKCZ,SPG11,TMEM201,ARHGAP21,DCTN1,SOD1,ICK,MAP1S,AP3M2,HTT
GO:0034502	protein localization to chromosome	GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME	0.266597469948176	0.958894311519433	0.520272108843537	0.84878537944517	36	GSG2,CENPA,ESR1,EZH2,SPO11,ACD,TERF2IP,CDK1,ATRX,WRAP53,BRCA2,PLK1,MTBP,PARP3,ATR,TNKS
GO:0032200	telomere organization	GO_TELOMERE_ORGANIZATION	0.224287940119262	0.967525313969116	0.520467327146414	0.84878537944517	88	TFIP11,SMG6,HIST1H3G,HIST1H3B,SP100,SMG1,POLA2,OBFC1,HIST1H4F,ERCC1,H3F3A,POLD2,ERCC4,ACD,TERF2IP,RFC3,HIST1H3E,PRKDC,MRE11A,WRAP53,PRIM1,HIST1H4A,BRCA2,WRN,NSMCE2,DCLRE1A,HIST3H3,UPF1,ATM,PARP3,RPA1
GO:0019098	reproductive behavior	GO_REPRODUCTIVE_BEHAVIOR	0.282193185684562	0.956192020213636	0.521642132211758	0.850289306065268	28	APP,OPRK1,PTEN,NCOA1,NHLH2,TH,PPP1R1B,OXT,MTNR1A,GRN,NCOA2,THRA,GRIN1,DBH
GO:2001259	positive regulation of cation channel activity	GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY	0.271359653732094	0.956649898593943	0.522066326530612	0.850568855325286	33	ANK2,CALM3,CACNA2D1,S100A1,RNF207,AKAP6,CALM1,ANK3,HTT,TRDN,JPH2
GO:0051604	protein maturation	GO_PROTEIN_MATURATION	-0.187352583903665	-0.976932153526223	0.522885170825636	0.85116901949957	240	CMA1,CTSE,BBC3,P2RX1,ADAMTS3,SCG5,DAP,IFT57,CPA3,CPXM1,CPZ,SERPINH1,SEC11C,RHBDF1,CYCS,SNCA,CALR,PCSK1N,F7,BOK,PYCARD,RIPK1,PCSK1,TSPAN15,PRSS12,TRADD,F2,EIF2AK3,CASP3,RPS27L,MME,SORL1,PPARG,S100A9,TSPAN5,POMC,GGT1,TMPRSS2,SPCS1,PROS1,FAS,NLRP3,NLRP12,CAPN1,CAPN2,BAX,NOD1,ASPH,F2R,AGA,CLN3,HM13,SENP1,RCE1,FSHB,TESC,IFI16,APH1B,F3,PAWR,PSEN1,RET,DYNC2H1,TYSND1,MMP14,ANP32B
GO:0042304	regulation of fatty acid biosynthetic process	GO_REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS	-0.264136340211833	-0.953860836142279	0.523563460557539	0.85116901949957	32	APOC1,ACADL,SLC45A3,ANXA1,SCAP,NR1H3,HNF4A,SIRT1,PLA2G4A
GO:0097202	activation of cysteine type endopeptidase activity	GO_ACTIVATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY	-0.215451573281391	-0.966596379951321	0.523574368018812	0.85116901949957	89	BBC3,P2RX1,DAP,IFT57,CYCS,SNCA,BOK,PYCARD,RIPK1,TRADD,EIF2AK3,CASP3,RPS27L,PPARG,S100A9,FAS,NLRP3,NLRP12,BAX,NOD1,ASPH,F2R,SENP1,IFI16,F3,PAWR,RET
NA	presynaptic process involved in synaptic transmission	GO_PRESYNAPTIC_PROCESS_INVOLVED_IN_SYNAPTIC_TRANSMISSION	0.216818218373002	0.966774123809947	0.523708117948101	0.85116901949957	107	C2CD4A,BRSK1,SLC6A2,CHAT,SLC5A7,CPLX1,SYT9,NRXN1,SYT8,CPLX3,SYTL2,VAMP2,STX1A,SYT7,CADPS,PPFIA4,STX4,PARK7,SYT12,PPFIA1,SYTL3,CACNA1B,P2RX7,BAIAP3,RPH3AL,PIP5K1C,GRM4,C2CD4B
GO:0046329	negative regulation of jnk cascade	GO_NEGATIVE_REGULATION_OF_JNK_CASCADE	-0.264003474564079	-0.953381025837651	0.524250959171453	0.85116901949957	32	MAPK8IP1,SFRP2,MEN1,TP73,HDAC3,FKTN,ZNF675
GO:0090174	organelle membrane fusion	GO_ORGANELLE_MEMBRANE_FUSION	0.224608636297113	0.964739886544794	0.524585302890234	0.85116901949957	86	C2CD4A,DYSF,SYT9,VCPIP1,SYT8,VPS4A,SYTL2,VAMP2,STX1A,SYT7,VPS11,VTI1A,VPS39,STX4,SEC22C,SYT12,SYTL3,VAMP1,RPH3AL,GOSR1,TMEM175,C2CD4B,UVRAG,STX10,DOC2B,LRMP,SYTL4
GO:0006914	autophagy	GO_AUTOPHAGY	0.187786494968738	0.978336061581928	0.524604059081134	0.85116901949957	352	DPF3,C6orf106,MARK2,LRSAM1,WDFY3,RRAGB,OBSCN,MYOM1,UBQLN4,SCN1A,MAP1A,ATG14,TP53INP2,DYNLL2,ATPIF1,TNIK,MFN2,USP30,ACIN1,RRAGD,VPS4A,ULK1,LRRK2,CALCOCO2,ATG16L1,HIST1H3G,SLC6A1,RAB12,PRKAB2,MFN1,NDUFB9,HIST1H3B,PINK1,USP13,VPS11,RAB1B,PRKAA2,C9orf72,PIK3C3,VPS37B,WIPI2,MDH1,DZANK1,PLEKHM1,VTI1A,PI4K2A,MTSS1,VPS39,MYLK,FNBP1L,PFKP,MTOR,FOXO1,LSM4,ADAMTS7,PARK7,ATG9A,ULK3,HDAC6,ALKBH5,VDAC1,CD93,HIST1H3E,REP15,TFEB,MAP1LC3A,NPC1,C1orf210,MAP1S,ZNF189,VPS37C,ITPKC,HMGB1,CA7,MLST8,WDR45,CHMP6,EPM2A,ATG16L2,PRKAG3,PRKG1,FAM13B,MTMR14,UVRAG,CAPS,MAP1LC3B,ACBD5,FCGR3B,MBD5,TSG101,CALCB,EIF2S1,RIMS3,PRKAG1,AMBRA1
GO:0048588	developmental cell growth	GO_DEVELOPMENTAL_CELL_GROWTH	0.231315237560185	0.962848366617831	0.524882496875385	0.85116901949957	72	AGT,NLGN3,NRP1,APP,TIAM1,ULK1,ZEB2,LAMB2,DCLK1,POU4F3,TGFBR2,AGTR2,LHX2,PRKCZ,SPG11,ARIH2,GDF9
GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	0.269240871414679	0.955815140124879	0.524956344586729	0.85116901949957	34	BAD,DYNLL2,ATPIF1,GZMB,GSK3B,NMT1,PPP3R1,PPP1R13B,BID,MAPK8,YWHAG,BAK1,TP53BP2,BMF
GO:0051145	smooth muscle cell differentiation	GO_SMOOTH_MUSCLE_CELL_DIFFERENTIATION	0.276711793751201	0.953681266150734	0.525199277675428	0.85116901949957	30	ITGA8,MKL2,MKL1,TMEM204,NFATC4,SIX1,VEGFA,SOX9,HEY2,ADM,MEF2C,SRF,SGCB,MYOCD
GO:0060428	lung epithelium development	GO_LUNG_EPITHELIUM_DEVELOPMENT	-0.260041361000635	-0.953153412037349	0.525318704748368	0.85116901949957	34	BMP4,GRHL2,MAP2K2,FOXA1,ERRFI1,WNT7B,SPDEF
GO:0045321	leukocyte activation	GO_LEUKOCYTE_ACTIVATION	-0.178584834922697	-0.98093698839696	0.525469168900804	0.85116901949957	380	MRGPRX2,TCF3,TYRO3,DPP4,CCL3,CCL19,CD7,ANXA3,IL18,CYP26B1,PTPN2,TNFSF14,ELF4,GATA3,CEBPB,CD79B,IMPDH2,SNCA,ANXA1,CLCF1,BATF3,PLA2G2D,FUT7,RAG2,CTNNB1,S100A12,PYCARD,CCL21,NR4A3,RIPK2,STXBP3,CSF1,SLC7A2,IFNA14,SNAP23,EXOSC6,IRF4,RIPK3,ULBP3,LEP,TNFSF9,CHRNB2,CEBPG,VAMP8,MT1G,CBFB,IFNE,RPL22,NKX2-3,RAG1,ZBTB1,CMTM7,SELPLG,EIF2AK4,ATP11C,LAT,ONECUT1,FAS,APBB1IP,CLEC4E,IFNA16,AKAP17A,IFNAR1,BAX,KLF6,ADAM9,NKAP,FLT3,RNF8
GO:0060479	lung cell differentiation	GO_LUNG_CELL_DIFFERENTIATION	0.289172923871321	0.952044801407743	0.526233689967151	0.851573631981081	25	YAP1,NFIB,EYA1,GPSM2,AIMP2,CREB1,SOX9,AGR2
GO:0038128	erbb2 signaling pathway	GO_ERBB2_SIGNALING_PATHWAY	-0.256388443454764	-0.952987231318179	0.526862312543174	0.851573631981081	36	NRG4,KRAS,EGFR,UBA52,GRB7,HSP90AA1,CPNE3,MATK,UBB,NRG1,HRAS
GO:0001819	positive regulation of cytokine production	GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION	-0.180202527331049	-0.979655749761432	0.527088190920313	0.851573631981081	345	TNFRSF8,C3,POLR3D,APOA2,CCL3,GSDMD,SULF1,CCL19,MAPK13,IL17B,RARA,IL18,POLR2H,FFAR3,WNT5A,LY96,GATA3,CEBPB,TBC1D23,IL27,MB21D1,ANXA1,IRAK1,XBP1,CTNNB1,SULF2,POLR3G,IL6ST,PYCARD,HPSE,NR4A3,RIPK2,RIPK1,LPL,POLR2K,IL36B,HIF1A,EIF2AK3,IRF7,IRF4,SAA1,ADIPOQ,LEP,IL17RC,TNFSF9,LILRB2,CEBPG,C5AR1,CLEC5A,IL17F,HGF,C5,CLEC4E,NLRP3,NLRP12,TLR9,CD34,IFNAR1,ADCYAP1,THBS1,NOD1,HMGB2,F2R,TXK,TLR2,NODAL,TMF1,MIF,VTCN1,FCER1A,IL17RB,MAPK11,ELANE,PTGER4,IFI16,AFAP1L2,ABL1,CARD9,IL20RB,CD276,XRCC5,IL4R,CD46,PF4
GO:0001952	regulation of cell matrix adhesion	GO_REGULATION_OF_CELL_MATRIX_ADHESION	0.224762218561349	0.96316500109155	0.527422990232908	0.851573631981081	85	PIK3R1,GPM6B,CLASP1,DLC1,ROCK2,TSC1,EPHA1,MACF1,GSK3B,PTEN,ACER2,EPHA3,PRKCZ,CDH13,DAPK3,TEK,VEGFA,LDB1,PLAU,CD36,SMAD3,LIMS1,BCL6,BCAS3
GO:1903426	regulation of reactive oxygen species biosynthetic process	GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS	-0.230741592696297	-0.9603877957519	0.528219904866447	0.851573631981081	60	ASS1,PTGIS,ZNF205,TSPO,SNCA,OPRM1,KLF4,STAT3,EGFR,AGXT2,SLC18A2,CD34,DDAH2,HSP90AA1,PKD2,EDN1
GO:0007416	synapse assembly	GO_SYNAPSE_ASSEMBLY	-0.226009092055834	-0.960661392393452	0.528928488775746	0.851573631981081	67	NLGN1,FLRT3,PCDHB10,WNT5A,PCDHB5,GPM6A,BSN,SPOCK2,CLSTN3,PCLO,CDK5,NLGN4Y,MAGI2,PCDHB16,CDH1,SPTBN2,NRCAM
GO:1901018	positive regulation of potassium ion transmembrane transporter activity	GO_POSITIVE_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.32396861499349	0.946615242933382	0.529132980206301	0.851573631981081	16	ANK2,RNF207,AKAP6,ATP1B2,ACTN2,DNM2
GO:2000251	positive regulation of actin cytoskeleton reorganization	GO_POSITIVE_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION	-0.314446727667933	-0.944833289875141	0.529428317856138	0.851573631981081	16	BAIAP2L2,BAIAP2,CDK5,RAPGEF3
GO:0034330	cell junction organization	GO_CELL_JUNCTION_ORGANIZATION	-0.195669323783175	-0.971281363015715	0.529836393155989	0.851573631981081	167	CLDN1,CDH7,PRKCA,PARD6B,PIP5K1A,OCLN,LAMA3,LAMC2,LSR,GRHL2,PRKCI,MPP7,CLDN9,CAMSAP3,MARVELD2,ACTG1,CTNNB1,DLG5,WHAMM,CDH15,RAB13,RHOD,CDH11,CDH3,MPP5,CDH8,CDH4,KRT14,CDH1,PDPK1,FBF1,ZNF703,F11R,RHOA,CDC42,HNF4A,LAMB3,DLG1,UGT8,ITGB4,BCL2,PLEC,HEG1,RAC1,RHOC,ACTN1,RCC2,FSCN1,TRIP6,PARD3,SNAI2,PTK2B
GO:0006749	glutathione metabolic process	GO_GLUTATHIONE_METABOLIC_PROCESS	-0.236988289723988	-0.956761421230992	0.530002038643622	0.851573631981081	52	CHAC2,GSTZ1,MGST1,GSTM3,EEF1G,CHAC1,CLIC3,GGT1,GGCT
GO:0090280	positive regulation of calcium ion import	GO_POSITIVE_REGULATION_OF_CALCIUM_ION_IMPORT	0.246070765989074	0.95636944440072	0.530040459737191	0.851573631981081	51	PDGFB,TRPV2,CALM3,CAPN3,XCL1,LGALS3,CXCL11,AKAP6,CXCR3,UCN,CALM1,CXCL9,PLCG1,ZP3,HTT,TRDN,JPH2
GO:0060416	response to growth hormone	GO_RESPONSE_TO_GROWTH_HORMONE	0.275862763044736	0.95075510001894	0.530251901574157	0.851573631981081	30	TRIM16,PIK3R1,STAT5B,JAK2,GH1,PXN,HMGCS2,MAPK1
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	GO_POSITIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA_STIMULUS	-0.282432241205908	-0.948183071054962	0.530704447758575	0.851573631981081	24	CDKN2B,SNW1,NPNT,MEN1,DAB2
GO:0071407	cellular response to organic cyclic compound	GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND	0.184215075188387	0.977958412174787	0.531184021945168	0.851573631981081	425	NR1I2,P2RY1,NR3C2,ADAR,GNAS,METTL3,RAPGEF1,PRKACA,BAD,PPARD,ESRRA,AKT2,PDGFB,NPM1,OSBPL7,NR2F6,HDAC2,LRP6,TRPV1,APP,PPARA,ROCK2,P2RY2,LRRK2,ZCCHC11,AKAP1,ESR1,GNG2,GLI2,RYR2,ATP1A2,SMAD1,RNF14,CTNNA1,UGT3A2,ABHD2,NKX3-1,RAE1,BTRC,GSK3B,AKAP6,RAPGEF2,JAK2,REST,MED24,RGS20,ADCY5,SLC8A1,MED12,RXRB,AGTR2,UBR5,LIN28B,PDE2A,H2AFZ,AR,IFIT1,RXRG,EP300,MED17,RAMP3,RHOXF1,P2RY13,ESR2,THRAP3,FOXO1,HMGCS2,TNF,SRRT,TMEM173,CDKN1B,FHL2,RXRA,HNRNPA2B1,TRIM24,HMGCS1,PTCH1,NCOA3,P2RX7,ESRRG,CYBA,PELP1,SOD1,DICER1,TRIP4,SLC26A3,PLAU,NPC1,SMAD9,SSH1,IMPACT,ABCB4,ELK1,CRHBP,PTAFR,IL17A,NFKB1,NCOA1,SMAD3,ABCG2,NR2F1,ATP1A3,WBP2,DDX54
GO:0042474	middle ear morphogenesis	GO_MIDDLE_EAR_MORPHOGENESIS	-0.295733582881469	-0.94503517736556	0.531308472216179	0.851573631981081	20	RPL38,NKX3-2,OSR1
GO:0015849	organic acid transport	GO_ORGANIC_ACID_TRANSPORT	-0.186322617680996	-0.974468792808443	0.531333732213002	0.851573631981081	245	SLC1A6,PDPN,SLC26A9,SLC36A2,PLIN2,SNAP25,NMB,EMB,MFSD2A,SLC10A3,SLC22A4,SLC1A1,SLC7A3,SLC10A1,SLC17A5,ANXA1,SLC6A17,SLC38A2,ABCB11,SLC7A10,SLC17A7,SLC7A8,SLC7A2,PRAF2,LEP,PLA2G4F,SLC25A22,SLC1A4,PPARG,FOLR3,UNC13B,SERINC2,BDKRB2,SLC16A1,ARL6IP5,SLC38A1,SLC13A5,AGXT,SLC38A8,SLCO1B3,STXBP1,CROT,FABP1,CACNB4,SLC6A14,SLC27A4,SLC7A4,CLN3,SLC32A1,SLCO2A1,SLC7A9,SLC3A2,SLC23A2,SLC17A6,SLC38A11,GRM2,SLC6A9,AQP9,PSEN1,SLC16A2,ABCC4,SYT1,SLC16A8,SLC7A13,PLA2G4A,SLC16A4,SLC6A12,ACACA,SLC7A11,SH3BP4,AKR1C1,SLC38A5,SLC7A14
GO:0060042	retina morphogenesis in camera type eye	GO_RETINA_MORPHOGENESIS_IN_CAMERA_TYPE_EYE	0.253066105072741	0.952645117471677	0.531940567312022	0.851573631981081	44	LRP5,PTPRM,LRP6,PROM1,HIPK2,RPE65,RP1,GNAT2,TSPAN12,SOX9,CABP4,SDK1,LHX1,PROX1
GO:0007603	phototransduction visible light	GO_PHOTOTRANSDUCTION_VISIBLE_LIGHT	-0.29559525721216	-0.944593149029933	0.531982942430704	0.851573631981081	20	CNGB1,PDE6C,GNAT1,AIPL1,RS1,GNGT1,PDE6G,PDE6A,GRK1
NA	respiratory gaseous exchange	GO_RESPIRATORY_GASEOUS_EXCHANGE	0.253010898367197	0.952437296679268	0.532192705988294	0.851573631981081	44	COX15,ADRB2,ELN,NDST1,ADH5,TAS2R4,DACH1,STK40,COX11,MAPK8IP3,ECEL1
GO:0032008	positive regulation of tor signaling	GO_POSITIVE_REGULATION_OF_TOR_SIGNALING	0.282752138711623	0.949061016451583	0.532974378697141	0.851573631981081	27	FLCN,RRAGB,RRAGD,MIOS,WDR59,HTR6
GO:0032612	interleukin 1 production	GO_INTERLEUKIN_1_PRODUCTION	-0.319206958107414	-0.940373238147618	0.533147198233881	0.851573631981081	15	CMA1,ABCA1,NLRP3
GO:0061045	negative regulation of wound healing	GO_NEGATIVE_REGULATION_OF_WOUND_HEALING	-0.233343134318947	-0.95668564225437	0.533271087629805	0.851573631981081	56	VTN,C1QTNF1,ANXA5,SERPING1,ANXA2,F2,PLAUR,ADAMTS18,SERPINB2,PROS1,CD34,CASK,ABAT,EDN1
GO:0040013	negative regulation of locomotion	GO_NEGATIVE_REGULATION_OF_LOCOMOTION	-0.186604879641717	-0.973624434656959	0.533324668572914	0.851573631981081	241	SEMA3F,IFITM2,TIMP1,SEMA3C,CCL28,SULF1,SPINT2,WNT5A,SFRP2,TRIM11,PTPN2,HOXA7,GATA3,FAM60A,ADAM15,ITGB1BP1,SEMA3A,SEMA3B,MID2,KLF4,EVL,HAS1,STAT3,MIA3,CCL21,ACVR1C,ANGPT4,ROBO2,SEMG2,FCN3,ADIPOQ,BMP5,MMP28,SEMA3D,CERS2,DPYSL3,NOV,TPM1,MAGI2,IL24,PTPRU,C5,DCN,RAP2B,CORO1C,SEMA3E,THBS1,KRT16,SEMA4B,LRP1,RHOA,SEMA4A,NODAL,OSBPL8,SRGAP2
GO:0006898	receptor mediated endocytosis	GO_RECEPTOR_MEDIATED_ENDOCYTOSIS	-0.19102905269014	-0.971597046468253	0.533539757874166	0.851573631981081	198	VTN,TMPRSS3,LRP2,EZR,MLC1,CFI,PRG4,COLEC12,RAB31,HP,HHIPL1,AMN,SCARA3,SNCA,CALR,CANX,CD5L,PRSS12,LRP8,HTR1B,SAA1,GTF2H2,DAB2,MASP1,CDK5,HPR,SORL1,SPARC,TMPRSS2,SYT5,SCYL2,IGKC,HSP90AA1,CLN3,LRP1,SCGB3A2,IGLC1,SLC9A3,SUSD2,SCARA5
GO:0001954	positive regulation of cell matrix adhesion	GO_POSITIVE_REGULATION_OF_CELL_MATRIX_ADHESION	-0.251268930712697	-0.951431442764375	0.533598961364552	0.851573631981081	39	CCL28,KDR,S100A10,ITGB1BP1,CCL21,CSF1
GO:1901343	negative regulation of vasculature development	GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	-0.221817520939973	-0.959762039705036	0.533836326606184	0.851573631981081	73	SULF1,NPR1,WT1,BMP4,ITGB1BP1,KLF4,KLK3,ANGPT4,TNMD,SPARC,IL17F,DCN,SEMA3E,THBS1,THBS2,RHOA,SEMA4A,PTGER4,THBS4,GTF2I,PF4,SERPINF1,PDCD10,MAP2K5,PDE3B,KRIT1,FOXC1
GO:0032147	activation of protein kinase activity	GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY	0.192928669232496	0.972581785669197	0.534099159419822	0.851573631981081	260	MADD,MARK2,RAPGEF1,PRKACA,TAOK2,MAPKAPK2,PDGFB,TNIK,LPAR3,DRD4,FLT1,ADRB2,ZAK,LRRK2,ITGB3,MAP3K15,STRADA,CRKL,DRD2,ADRA2C,PINK1,MAPKAPK3,NKX3-1,PLCE1,JAK2,STRADB,ADCY7,MAP3K4,UCN,PRKAR1A,ADCY5,TGFBR2,MAPKAPK5,TGFA,RAF1,GPRC5B,PRKCZ,TNFRSF10B,ADCY8,ADCY9,DBNL,DUSP19,TNF,PARK7,MAPK1,ADCY4,CDK1,VEGFA,PKN1,P2RX7,SOD1,CCDC88A,GADD45A,WNT11,MAPK8IP3,MALT1,ADORA2B,PLCG1,CLSPN,MDFI,HMGB1,GRM4,GAB1,DUSP7,MAP4K2
GO:0033574	response to testosterone	GO_RESPONSE_TO_TESTOSTERONE	0.264392418366635	0.95096321067831	0.534167800453515	0.851573631981081	36	NASP,BAD,ADRB2,ROCK2,NKX3-1,PLN,PSPH,ESR2,HMGCS2,ELK1,GNRH1,CAD
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	GO_CYTOPLASMIC_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY	-0.266599249480423	-0.947376738015694	0.534208371145886	0.851573631981081	30	IRAK1,RIPK2,CHUK,UBA52,IRF7,IKBKG,NOD1,UBB,TAB2,MAP3K7,LSM14A,RPS27A,IRF3
GO:0046135	pyrimidine nucleoside catabolic process	GO_PYRIMIDINE_NUCLEOSIDE_CATABOLIC_PROCESS	0.312751842964615	0.943569692597838	0.534433778338935	0.851573631981081	18	UPP2,ENTPD4,AICDA,APOBEC3H,UPB1,APOBEC1
GO:0006929	substrate dependent cell migration	GO_SUBSTRATE_DEPENDENT_CELL_MIGRATION	0.287530991039258	0.946639061492335	0.5346020443743	0.851573631981081	25	NRP1,ATP5B,FGFR1,ANKS1A,OPHN1
GO:0042753	positive regulation of circadian rhythm	GO_POSITIVE_REGULATION_OF_CIRCADIAN_RHYTHM	-0.294990420654268	-0.942660355945714	0.534680823288804	0.851573631981081	20	NLGN1,NPY2R,ARNTL2
NA	purinergic receptor signaling pathway	GO_PURINERGIC_RECEPTOR_SIGNALING_PATHWAY	0.290395263894956	0.946261089963055	0.535106422085799	0.851573631981081	24	P2RY1,P2RY2,ADCY5,P2RY13,P2RX7,ADORA2B,PTAFR,P2RX2,GPR171
GO:0050805	negative regulation of synaptic transmission	GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION	0.239176354982163	0.953993150746647	0.53514283171665	0.851573631981081	58	NLGN3,GPM6B,SLC24A2,LRRK2,DRD2,SLC6A1,ARF1,PTEN,ABHD6,GRIA1,PPP1R9A,GABBR1,NPY5R,GRID2IP,CD38,SLC30A1,NLGN4X,PCDH17,MTMR2,SRF
GO:0006816	calcium ion transport	GO_CALCIUM_ION_TRANSPORT	0.198043714086474	0.969353936114793	0.535268070256301	0.851573631981081	204	MICU1,TRPM4,CACNA2D4,IL1RAPL1,DENND5A,GRIN3A,ANK2,ITPR1,CATSPER2,DENND5B,SLC24A2,TRPV1,TRPV2,CAMK2A,CACNA2D1,ANXA6,RYR2,CACNA2D2,TPCN1,XCL1,DRD2,SLC24A1,PKD1L1,PANX1,CACNG1,MCOLN2,CYP27B1,PLN,GCK,SLC8A1,TRPM1,PDE2A,SRL,PKD2L2,CAMK2G,RAMP3,CACNA1C,LOXHD1,TRPC5,NPY,VDAC1,CACNA1B,P2RX7,ATP2C2,PKD2L1,NMUR2,ZP3,SLC30A1,CATSPER4,CUL5,CACNA1E,TRDN,ATP2A2,JPH2,PRKCE
GO:0051648	vesicle localization	GO_VESICLE_LOCALIZATION	-0.189841915519887	-0.971873604157765	0.535397664852712	0.851573631981081	208	STX19,HAP1,SYT4,SNAP25,NLGN1,TMED10,AREG,RAB27B,SYTL1,AP3M1,SYT17,SCFD1,BBS7,TMED2,TRIM9,ANKRD28,SNCA,KIF3A,CANX,RPH3A,SEC24D,CTNNB1,TOR1A,C2CD4D,GPR143,SNAP23,PCLO,WDR43,STX11,SEC24A,SYT6,SEC13,VPS33A,CDK5,IKBKG,COL7A1,UNC13B,AP3S1
GO:0046328	regulation of jnk cascade	GO_REGULATION_OF_JNK_CASCADE	-0.197522182962642	-0.968539626440343	0.535402834208701	0.851573631981081	154	EDA2R,MAPK8IP1,TNFSF11,CCL19,ARHGEF5,TRAF4,WNT5A,SFRP2,CTGF,MDFIC,TNXB,MEN1,EDAR,TP73,PYCARD,CCL21,RIPK2,RIPK1,HDAC3,STK3,RPS3,MAGI3,FKTN,SH3RF1,ZNF675,TLR9,MAP3K11,NOD1,GRIK2,PHLPP1,EDN1,CDC42,FCER1A,MAP3K2,RASSF2,AXIN1,CARD9
GO:0021987	cerebral cortex development	GO_CEREBRAL_CORTEX_DEVELOPMENT	0.217664346162622	0.96086467692915	0.535501579574292	0.851573631981081	101	NDE1,BAD,WDR62,NRP1,LRP6,PAFAH1B1,DIXDC1,VLDLR,TSC1,TRAPPC9,CDH2,GSK3B,LHX2,FGFR1,FBXO45,XAB2,HTR6,FAT4,NPY,PAX6,MKKS,NCOA1,MCPH1
GO:0071731	response to nitric oxide	GO_RESPONSE_TO_NITRIC_OXIDE	-0.290696266861353	-0.941118999725413	0.535585674065344	0.851573631981081	21	CCL19,AQP1,BMP4
GO:0006333	chromatin assembly or disassembly	GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY	0.206016058358432	0.965623911559281	0.536844229895884	0.851938985305206	148	SMARCB1,HILS1,NASP,CENPK,NPM1,PAF1,HIST1H2BO,CENPA,HIST1H3G,HIST1H3B,HMGA1,HELLS,SMARCD3,HIST1H4F,HP1BP3,HIST1H2BC,KAT6A,H3F3A,HIST1H2BA,H2BFWT,CENPN,HIRIP3,HIST1H3E,ASF1B,SOX9,ATRX,HIST2H2BE,HMGB1,CENPI,UBN1,TSPYL5,ASF1A,H1F0,HIST2H2BF,H1FX,KAT6B,HIST1H4A,HIST1H1D,SART3,CENPO,HIST1H1T,CENPV,CENPT,TSPYL6,HIST3H3
GO:0045824	negative regulation of innate immune response	GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE	-0.261975241475417	-0.946056580786694	0.536958594841543	0.851938985305206	32	TYRO3,PTPN2,SERPING1,RPS19,IRAK3,PPARG,NR1H3
GO:0045989	positive regulation of striated muscle contraction	GO_POSITIVE_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION	0.327339927448316	0.940600635065338	0.53705459209279	0.851938985305206	15	TRPM4,RNF207,UCN,ACE2,ATP2A1,GSTO1,KCNQ1
GO:0007632	visual behavior	GO_VISUAL_BEHAVIOR	0.251200320094648	0.950134456446515	0.537227249015128	0.851938985305206	45	NLGN3,APP,NDRG4,HRH2,ATP1A2,DRD2,HMGCR,NPS,MTOR,CREB1,RGS14
GO:0051480	regulation of cytosolic calcium ion concentration	GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION	0.199291768930341	0.968799416498794	0.537255161461091	0.851938985305206	194	P2RY1,PRKACA,TRPM4,OPRL1,ITPR1,DLG4,LPAR3,LRP6,NPY1R,TRPV1,P2RY2,CACNA2D1,ESR1,RYR2,TPCN1,XCL1,ATP1A2,DRD2,HRC,GIPR,GJA1,GLP1R,PLCE1,JAK2,CAV3,CXCR3,PLN,ADCY5,GCK,SLC8A1,TRPM1,CACNA1C,GNAT2,KCNA5,CCR2,TRPC5,S1PR1,P2RX7,NMUR2,CCR8,IL2,CD38,HMGB1,CD36,TRDN,GALR1,NPFF,JPH2,PRKCE,CALCR,TRPC7,LPAR2,ABL2,GATA2,PTH1R,ADM,TRPC6,IBTK
GO:0045980	negative regulation of nucleotide metabolic process	GO_NEGATIVE_REGULATION_OF_NUCLEOTIDE_METABOLIC_PROCESS	0.236692795120978	0.953835802226657	0.537334065895114	0.851938985305206	61	OPRL1,FLCN,DRD4,PPARA,APOC3,DRD2,PPIF,HDAC4,AKAP6,PDE2A,EGLN1,P2RY13,HTR1E,CCR2,GABBR1
GO:0022030	telencephalon glial cell migration	GO_TELENCEPHALON_GLIAL_CELL_MIGRATION	-0.307195948791983	-0.939498668843931	0.537829303110265	0.852322709166268	17	RTN4,CTNNB1,CDK5,SRGAP2
NA	nonmotile primary cilium assembly	GO_NONMOTILE_PRIMARY_CILIUM_ASSEMBLY	-0.290213802291994	-0.939557037551559	0.53848840000873	0.852928585740921	21	BBS7,CEP89,PCM1,ARL13B,CCDC13,BBS10
GO:0030837	negative regulation of actin filament polymerization	GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION	0.254828180760034	0.949229442122937	0.538718411552347	0.852928585740921	42	SPTB,LMOD1,LMOD3,ADD1,CAPZB,TMOD1,ARFGEF1,FHOD3,RDX,MKKS,KANK1,PFN2,CAPG,SPTBN1
GO:0070936	protein k48 linked ubiquitination	GO_PROTEIN_K48_LINKED_UBIQUITINATION	0.251955624180709	0.948464809723486	0.539252588923908	0.853329383496264	44	RNF187,NEDD4L,UBE2T,PELI1,MARCH6,RNF152,ARIH2,RNF115,UBE2B,CDC34,SYVN1,UBE2K,UBE2H,UBE3A,UBE2D4,UBE2D1,RNF4,RNF34,TNFAIP3,UBE2D3,UBE2Q2,UBE2R2,ITCH,UBE2D2,PARK2,KLHL3
GO:0003341	cilium movement	GO_CILIUM_MOVEMENT	-0.270255908846321	-0.944215334273066	0.539753293466028	0.853329383496264	28	CCDC114,TTLL1,DNAH1,ADCY10,ROPN1L,DNAH5,LRRC6,DPCD,SPA17,SPAG16,SPAG17,CCDC151,CABYR,CCDC40,DNAH11
GO:0032673	regulation of interleukin 4 production	GO_REGULATION_OF_INTERLEUKIN_4_PRODUCTION	-0.263658657332214	-0.944407233287071	0.539783802941698	0.853329383496264	31	RARA,GATA3,CEBPB,HLA-DRB5,IRF4,NLRP3,HLA-DRB1,IL20RB
NA	regulation of homeostatic process	GO_REGULATION_OF_HOMEOSTATIC_PROCESS	0.184247081690997	0.97516253733298	0.54035683942226	0.853329383496264	412	SMARCB1,LRP5,AGT,PRKACA,BAD,TRPM4,BMP8A,HMBOX1,FLCN,ANK2,ITPR1,NRXN1,STAT5B,TRPV1,TIAM1,SMG6,SCN5A,LRRK2,CALM3,ITGB3,RYR2,WNK1,MCRS1,TPCN1,NEDD4L,CAPN3,LDLR,XCL1,ATP1A2,DRD2,HRC,OPRK1,CDK16,WNK2,ADCYAP1R1,CXCL11,PINK1,GJA1,HMGCR,AKAP6,CAV3,OBFC1,PRKAA2,INPP5D,DMD,CXCR3,MAP3K4,PLN,ADCY5,SLC8A1,AGTR2,ANO1,ERCC1,MAPKAPK5,CALM1,TCP1,STX4,ERCC4,ADA,ACD,CACNA1C,GJA5,FOXO1,CCR2,TERF2IP,S1PR1,TNF,MAPK1,CA2,P2RX7,ETS1,CYBA,LDB1,ANK3,NPC1,CCT3,SPI1,CXCL9,ATRX,PLCG1,IL2,CD38,SLC30A1,ENY2,CD36,SMAD7,HTT,FGF12,ATP6AP1,TRDN,PASK,CA7,NPFF,JPH2,PRKCE,ITPKB,MRE11A,HMGN3,SLC27A1,MED1,EPHA5,DHRS7C,CCT7,GATA2,BAK1,WRAP53,CCT4,PRKCQ
GO:1901654	response to ketone	GO_RESPONSE_TO_KETONE	-0.193809609269408	-0.968683050017097	0.540393259837774	0.853329383496264	175	ASS1,C3,CCL19,CA9,AQP1,BMP4,WNT5A,NDOR1,TSPO,CALR,SOCS1,TACR1,KLF4,GNAI1,F7,P2RY4,SLIT3,ERRFI1,CCL21,CDKN1A,STAR,CPS1,MSTN,TYMS,SLC18A2,PPARG,PTGER2,NR1H3,FAS,HMBS,CHEK2,ADCY2,PTGS1,THBS1,BAX,KLF6,MSN
GO:0048665	neuron fate specification	GO_NEURON_FATE_SPECIFICATION	-0.263529606902679	-0.943944983496586	0.540492645755804	0.853329383496264	31	NKX6-1,FOXA1,HOXC10,OLIG3,EVX1,ISL2
GO:0007193	adenylate cyclase inhibiting g protein coupled receptor signaling pathway	GO_ADENYLATE_CYCLASE_INHIBITING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.23623479169969	0.951990118412986	0.540967336015455	0.853572592521803	61	P2RY1,OPRL1,RXFP2,DRD4,NPY1R,DRD2,OPRK1,ADCY7,ADCY5,ADCY8,ADCY9,HTR1E,S1PR1,GABBR1,ADCY4
GO:0032535	regulation of cellular component size	GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE	-0.180791482496817	-0.974601123033436	0.541195825130128	0.853572592521803	317	SEMA3F,ATP13A2,SEMA3C,EZR,NKX6-1,WASF1,AQP1,WNT5A,ULK2,AQP3,BAIAP2L2,ANO6,ALOX15,LIMA1,EFNA5,AQP8,ARPC5,RTN4,ARHGAP18,SEMA3A,SEMA3B,RAB3B,SPTBN4,EVL,ACTR3,KIRREL,ATP2B2,TMEM123,VILL,PLEKHH2,PLXNA2,NPHS1,PYCARD,CCL21,TWF1,WHAMM,HIF1A,SNF8,BAIAP2,TRIOBP,SEMA3D,CDK5,RND2,CDC42EP1,SCIN,FGF13,CDH4,RAPGEF3,PAK3,PICK1,CDHR5,DEPTOR,KCNN4,SEMA3E,CAPZA1,PFN3,E2F4,SPTBN2,MSN,WIPF2,SEMA4B,NRCAM,SSH3,HSP90AA1,SEMA4A,FSTL4,EDN1,WDR36,PLXNA4,SPTAN1,DLG1,TTL,ABL1,AQP9,RET,SWAP70,RNF6,RAB11A,RICTOR,NRG1,WNT3,SLC6A12,WNT7A,TRIM27,RAC1,NEB,PLXNA1
GO:0033866	nucleoside bisphosphate biosynthetic process	GO_NUCLEOSIDE_BISPHOSPHATE_BIOSYNTHETIC_PROCESS	0.320927912472782	0.937730507739554	0.541938481553759	0.853572592521803	16	PANK3,COASY,PANK4,ACACB
GO:0009566	fertilization	GO_FERTILIZATION	-0.201427596022807	-0.963871880077814	0.54222515198125	0.853572592521803	131	ZAN,ZP1,TARBP2,OR10J1,UBE2Q1,T,DUOX2,TDRD12,FUT10,SPTBN4,TNP2,REC8,PKDREJ,MST1R,ADAM30,ATP8B3,SERPINA5,PRDM14,PLCD4,SYT6,IZUMO1,SPEF2,ELSPBP1,ASTL,NLRP5,STX2,BAX,NPM2,AKAP4,CCT5,GNPDA1,CLGN,FOXL2,CATSPER1,CD46
GO:0060765	regulation of androgen receptor signaling pathway	GO_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY	0.298721202309348	0.940190706928039	0.542236494841555	0.853572592521803	21	RNF14,EP300,TCF21,PARK7,HDAC6
GO:0048872	homeostasis of number of cells	GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS	-0.195321419582803	-0.966507182507187	0.542546051159669	0.853572592521803	163	CD7,EPB42,BMP4,ILDR2,PTPN2,TNFSF14,KRAS,GATA3,SKIL,RPS19,ANXA1,CSF1,NLE1,CACNA1F,HIF1A,RPS24,L3MBTL3,PRDM14,RIPK3,HCAR2,EMX1,SOX6,CASP3,CEBPG,NOV,NKX2-3,RAG1,LAT,FAS,ETV2,BAX,FLT3,F2R,DNASE2,RPS17,IL2RA,SPNS2,RASSF2,INHBA,RPS6,ABL1,ARID4A,IL20RB
GO:0006026	aminoglycan catabolic process	GO_AMINOGLYCAN_CATABOLIC_PROCESS	-0.227865826496258	-0.95466675066827	0.542753573313144	0.853572592521803	62	CHI3L1,AGRN,GPC5,FMOD,SDC1,HPSE,IDUA,SGSH,PGLYRP1,DCN,STAB2,FGF2,PGLYRP2,VCAN,GUSB,CTBS,LUM,PRELP,LYG2,PGLYRP3,SDC2,HEXA,GPC3,NCAN,HYAL4,LYVE1,OMD,OGN,CHIA
GO:0007062	sister chromatid cohesion	GO_SISTER_CHROMATID_COHESION	0.21866325528017	0.957819562664617	0.543049335108682	0.853572592521803	96	GSG2,NDE1,CENPK,FBXW7,POGZ,CLASP1,CENPA,PAFAH1B1,RANGAP1,CLIP1,NUP85,MAD2L1
GO:0006403	rna localization	GO_RNA_LOCALIZATION	0.202582526827685	0.96423795991975	0.543156277656253	0.853572592521803	165	NOL6,POM121,NCBP1,SMG6,XPO7,TSC1,PRPF6,NUP85,QKI,SMG1,RAE1,DDX39B,SRSF4,TCP1,CPSF1,NUP188,NCBP2,PRPF31,HNRNPA2B1,RNPS1,EXOSC3,SRSF1,ALKBH5,ZNHIT6,RBFOX1,ENY2,HTT,TPR,AAAS,PARP11,DHX38,NXF3,CKAP5,RBM8A,POM121C,MRPL18,FLOT1,CHTOP,WRAP53,CCT4
GO:0071166	ribonucleoprotein complex localization	GO_RIBONUCLEOPROTEIN_COMPLEX_LOCALIZATION	0.214481711830196	0.958128868983838	0.543182558877511	0.853572592521803	108	NOL6,POM121,NCBP1,SMG6,TSC1,NUP85,SMG1,RAE1,DDX39B,SRSF4,NMD3,CPSF1,NUP188,NCBP2,PRPF31,HNRNPA2B1,RNPS1,SRSF1,ALKBH5,ENY2,TPR,AAAS,DHX38,NXF3,RBM8A,POM121C,CHTOP
GO:0071277	cellular response to calcium ion	GO_CELLULAR_RESPONSE_TO_CALCIUM_ION	-0.245519939281792	-0.94601128199249	0.544302946056231	0.854650278246091	42	WNT5A,ALOX15,KCNH1,AKR1C3,RYR3,CPNE6,ASPH,CPNE3,EDN1,JUNB,GUCA1A,SYT1,ACER1,JUN,ALOX5AP,FOS,SPAG16,IQGAP1,FOSB,CLIC4
GO:0034105	positive regulation of tissue remodeling	GO_POSITIVE_REGULATION_OF_TISSUE_REMODELING	-0.285844893521746	-0.937128527661823	0.544483596331882	0.854650278246091	22	TNFSF11,IL18,BAX,FSHB,PTGER4,SPP1,B4GALT1
GO:0001525	angiogenesis	GO_ANGIOGENESIS	0.191664687474466	0.969332793272757	0.54463007927447	0.854650278246091	267	ROBO4,LRP5,NRP1,EPAS1,PTPRB,NRXN1,NOTCH3,ZNF304,TIE1,ATPIF1,RNF213,FLT1,AAMP,ITGB3,BMPER,HAND2,EPHA1,CEACAM1,PRKX,COL15A1,VEGFB,FGF1,PTEN,CXCR3,ADIPOR2,SLC12A6,TGFBR2,HSPG2,NFATC4,ATP5B,E2F8,HS6ST1,SHH,CX3CL1,DLL4,RASIP1,FGFR1,ARHGAP22,TCF21,CDH13,GJA5,COL18A1,TBX20,WARS,TSPAN12,S100A7,S1PR1,PDCD6,SEMA5A,TEK,MCAM,SOX17,VEGFA,HOXB3,ETS1,ENG,PLCD3,PLAU,SH2D2A,SPI1
GO:0051590	positive regulation of neurotransmitter transport	GO_POSITIVE_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT	0.325248669694552	0.934591473926307	0.545716463131285	0.855884086693959	15	DRD4,DRD2,STX1A,RAB3GAP1
GO:0045616	regulation of keratinocyte differentiation	GO_REGULATION_OF_KERATINOCYTE_DIFFERENTIATION	-0.273971016237321	-0.939040809379293	0.546114422717375	0.855884086693959	26	AQP3,HOXA7,GRHL2,ERRFI1,MSX2,IL20
GO:0006213	pyrimidine nucleoside metabolic process	GO_PYRIMIDINE_NUCLEOSIDE_METABOLIC_PROCESS	0.257720509466843	0.944361872811221	0.546179149797571	0.855884086693959	39	TK1,UPP2,ENTPD4,UCKL1,NME6,AICDA,NME5,APOBEC3H,CAD,DHODH,UPB1,APOBEC1
GO:0071732	cellular response to nitric oxide	GO_CELLULAR_RESPONSE_TO_NITRIC_OXIDE	0.324838903557503	0.933414024258797	0.54720347961858	0.856773626764606	15	GUCY1B3,MTR,FOXO1,TPO,AIFM1,MT3,DNM2
GO:0007617	mating behavior	GO_MATING_BEHAVIOR	0.294289264668716	0.937377340083478	0.547347682789858	0.856773626764606	22	APP,PTEN,NCOA1,NHLH2,TH,PPP1R1B,OXT,MTNR1A,GRN,NCOA2,THRA,GRIN1
GO:0048285	organelle fission	GO_ORGANELLE_FISSION	0.182896649794415	0.973627291358114	0.547552469040961	0.856773626764606	439	FBXL7,GSG2,NDE1,SPAG5,TUBGCP5,NSUN2,CDC26,POGZ,SUN1,BIRC8,VCPIP1,CLASP1,BIRC6,KLHL21,PAFAH1B1,AKAP8,NEK1,VPS4A,DMC1,LFNG,NCAPH,CLIP1,TUBGCP2,ARHGEF2,MAD2L1,SYCP2,GOLGA2,SPANXA2-OT1,HELLS,FZR1,TEX11,CETN1,PBRM1,PTEN,CHMP7,SPIRE1,ANAPC1,KLHDC3,RAD21L1,PRKAR1A,COX10,TTN,GORASP1,SMC1A,PPP5C,LATS1,SPO11,FAM83D,SMC2,ERCC4,WASL,MAU2,MLH3,KIFC1,ANAPC11,NEK9,INCENP,MAPRE2,RECQL5,RGS14,CENPN,ACOT8,CDK1,PPP1R12A,NAA50,DCTN1,NCAPD3,PLD6,CNTD1,TDRKH,CDC25C,DLGAP5,PRDM9,SETDB2,PBK,TUBGCP6,HFM1,KIF25,CCNA1,CLTCL1,CEP57L1,BAG6,CSNK1A1,DMRTC2,CHMP6,KLHL22,TPR,HAUS8,ZWILCH,MAD1L1,TUBGCP3,MRE11A,OPA1,CKAP5,UBE2B,UBR2,CHFR,UBE2I,ESPL1,TIPIN,CCDC155,AKAP8L,BABAM1,MAPRE3,DIS3L2,BRCA2,TOP2B,MAPRE1,EREG,SPIRE2,CHMP1B,PAPD7,CLASP2,PHF13,MTFR1,NSMCE2,SIRT2,KPNB1,FIGN,TTC28,WEE1,CENPV,CHMP4B,CENPT,MLH1,SKA2,PLK1,DCLRE1A,USP44,CDCA3,CHMP4C,MEI1,TOP3A,PEX19,KIF23,EML4,NCAPD2,KIF3B,PPP2R1A,ASZ1,KLHL9,UBE2S,BRDT,DUSP13,DCTN3,ATM,REEP4
GO:0046890	regulation of lipid biosynthetic process	GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS	-0.204359758393993	-0.959373312624155	0.548004054641116	0.856773626764606	116	C3,SMPD3,APOC1,ACADL,ORMDL2,SLC45A3,BMP2,CYR61,TSPO,ANXA1,SMPD2,XBP1,THRSP,AKR1C3,DGAT2,STAR,TNFRSF1A,SCAP,BMP5,LEP
GO:0050864	regulation of b cell activation	GO_REGULATION_OF_B_CELL_ACTIVATION	-0.207338022008011	-0.959028457639172	0.548019494481342	0.856773626764606	106	TCF3,TNFRSF21,MZB1,CLCF1,XBP1,BST1,CDKN1A,SLC39A10,IGHG4,CASP3,CHRNB2,IGHG2,IGHG1,WHSC1,ATP11C,FAS,IGHD,IL5,IGKC,AHR,APLF,IGLL1,MIF,IGLC1,INHBA,PAWR,BANK1,IL10,MMP14,BCL2,CD81,ZAP70,PRDM1
GO:0042755	eating behavior	GO_EATING_BEHAVIOR	-0.264202362547573	-0.938859253708211	0.54866198897718	0.857379876925342	30	NMU,OPRM1,TACR1,STAT3,PRLH,LEP,IAPP,OPRD1,BSX,HCRT
GO:0033139	regulation of peptidyl serine phosphorylation of stat protein	GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION_OF_STAT_PROTEIN	-0.291919883047239	-0.932848260803213	0.550128366911797	0.859272428317915	20	IFNA14,IFNE,IFNA16,RET,IFNA2,IFNA5,IFNG,IFNA13
GO:0006305	dna alkylation	GO_DNA_ALKYLATION	0.254332205903749	0.942346011596267	0.550921242774566	0.860111736168456	41	GNAS,PRMT7,TDRD5,ZFP57,EZH2,CTCFL,PLD6,TDRKH,ATRX,BAZ2A,GATAD2B,ASZ1,TRIM28,MAEL,PIWIL2,CTCF,MTRR,ATF7IP
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.219819146363341	0.953524066216963	0.55154630224522	0.860383759602171	91	NRP1,CFLAR,BIRC6,YAP1,LGALS3,ARHGEF2,EYA1,CTNNA1,STRADB,CX3CL1,AR,RAF1,TNFRSF10B,TNFSF10,IL4,TNF,CSF2,PARK7
GO:0002828	regulation of type 2 immune response	GO_REGULATION_OF_TYPE_2_IMMUNE_RESPONSE	0.287097721882066	0.935515957079465	0.55174061684373	0.860383759602171	24	RSAD2,HLX,XCL1,IDO1,PRKCZ,CCR2,BCL6,TNFSF4
GO:0043123	positive regulation of i kappab kinase nf kappab signaling	GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING	-0.193812359970681	-0.963063610753763	0.552221638786788	0.860383759602171	168	EDA2R,TNFSF11,CCL19,IL18,IRAK4,PRKD1,TRAF3IP2,TNFSF14,LPAR1,TRAF5,MID2,IRAK1,EDAR,CTNNB1,TRIM62,S100A12,CCL21,RIPK2,RIPK1,CHUK,TRADD,UBA52,TNFRSF1A,ADIPOQ,TRIM38,IKBKG
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS	-0.265662248696121	-0.93612969619342	0.552250359394006	0.860383759602171	29	BBC3,CEBPB,CHAC1,XBP1,BRSK2
GO:0071236	cellular response to antibiotic	GO_CELLULAR_RESPONSE_TO_ANTIBIOTIC	-0.30925297135119	-0.929227359090134	0.55237353074875	0.860383759602171	16	CRIP1,STAR,RAB10,PLA2G4F,HMBS,MDM2,PLA2G4A
GO:0051607	defense response to virus	GO_DEFENSE_RESPONSE_TO_VIRUS	0.204996385247894	0.958628087709452	0.553293756535231	0.860729030606434	146	ADAR,RSAD2,UNC13D,IFI44L,OPRK1,PCBP2,ABCF3,HERC5,SERINC5,ADARB1,OAS2,EXOSC4,DDX58,CD8A,IFIT2,POLR3F,CD40,IFIT1,OASL,OAS3,IRF1,OAS1,GBP1,TMEM173,APOBEC3D,MICA,CXCL9,APOBEC3H,HYAL2,POLR3K,POLR3H,LILRB1,APOBEC1,IFNA21,DDIT4,ABCC9,C19orf66,IFNA4,DDX60,TICAM1
NA	single organism behavior	GO_SINGLE_ORGANISM_BEHAVIOR	0.185700920242323	0.969525744123624	0.553319446837168	0.860729030606434	359	CPEB3,SHANK3,CHAT,NLGN3,USP46,ITGA8,SCN1A,NRXN1,PREX2,DLG4,SLC24A2,HDAC2,DRD4,VIP,PAFAH1B1,TRPV1,APP,DDO,ALS2,ADRB2,PPARA,NDRG4,LRRK2,VLDLR,TSC1,HRH2,SHANK1,MUSK,ATP1A2,DRD2,OPRK1,HIPK2,GHSR,SLC6A1,RNF180,GLP1R,HMGCR,OSM,CHD7,GPR52,USP2,SNCG,RASGRF1,PTEN,UCN,CLN8,GRIA1,AGTR2,NPS,SLC4A10,NPTX2,EP300,PRKCZ,TMOD1,PAIP2,FBXL20,ADCY8,ESR2,MTOR,CREB1,RGS14,PARK7,NPY,HOMER1,VDAC1,NPC1,EPHA4,TANC1,NMUR2,CRHBP,FXN,HTT,SDK1,FGF12,BHLHB9,UBR3,ATP1A3,GIGYF2,EPM2A,AAAS,PRKCE,NTF4,NLGN4X,PCDH17,EIF4G1,MTA1
GO:0043090	amino acid import	GO_AMINO_ACID_IMPORT	-0.314470889508623	-0.926420935256916	0.553362335779062	0.860729030606434	15	SLC1A1,SLC17A7,SLC7A2,SLC3A2,SLC6A9,SH3BP4
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES	-0.207111897610799	-0.956240298742462	0.554125680450769	0.861040703070108	105	CDH7,DSC3,IGSF9,CD200,PCDHB10,PCDHB5,CDH15,CLSTN3,ROBO2,CDH11,CDH3,CDH8,CDH4,AMIGO2,MPZL2,PCDHB16,CDH1,CDHR5
GO:2000377	regulation of reactive oxygen species metabolic process	GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS	-0.198407570221597	-0.960355299102361	0.554142004568116	0.861040703070108	141	ASS1,PTGIS,FOXM1,HP,ZNF205,TSPO,SNCA,OPRM1,AGTR1,KLF4,STAT3,AKR1C3,RIPK1,CDKN1A,EGFR,HIF1A,F2,RIPK3,AGXT2,LEP,DUOXA1,SLC18A2,HK2,DHFR,CD34,DDAH2,THBS1,NOXA1,HSP90AA1,PKD2,EDN1,FOXO3,NFE2L2,MYCN,PTGER4
GO:0021533	cell differentiation in hindbrain	GO_CELL_DIFFERENTIATION_IN_HINDBRAIN	0.300447564969346	0.932620793932983	0.554330125832716	0.861040703070108	20	HERC1,ATP7A,NRXN1,CBLN1,LDB1,LHX1,PROX1,GATA2,PHOX2B,AGTPBP1
GO:0045776	negative regulation of blood pressure	GO_NEGATIVE_REGULATION_OF_BLOOD_PRESSURE	0.252296876382657	0.939800388260781	0.554891696750903	0.861515429549602	42	OPRL1,ADRB1,ADRB2,PPARA,DRD2,UCN,AGTR2,GJA5,SOD2,MKKS,PTAFR,SCPEP1,KCNK6,ADRB3,UTS2,NOS2,OXT
GO:0050714	positive regulation of protein secretion	GO_POSITIVE_REGULATION_OF_PROTEIN_SECRETION	-0.189675364636768	-0.964712024028084	0.555341234994036	0.861536528255015	198	ATP13A2,CFTR,RBP4,EZR,CCL3,GSDMD,CCL19,NKX6-1,WNT5A,GATA3,HLA-DRB5,XBP1,PYCARD,LPL,SERP1,HIF1A,SAA1,HCAR2,SEC24A,IL17RC,NNAT,CLEC5A,IL17F,C5,CLEC4E,SLC30A8,NLRP3,IL5,NLRP12,CD34,KCNN4,STXBP5L,IFNAR1,ADAM9,F2R,ABAT,MIF,VTCN1,HLA-DRB1,IL17RB,MAPK11,PTGER4,ABL1,CD276,IL4R,GOLPH3L,IL10
GO:0046641	positive regulation of alpha beta t cell proliferation	GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION	-0.294780488126558	-0.928427076726754	0.555541074764325	0.861536528255015	19	CD55,IL18,RIPK2
GO:2001021	negative regulation of response to dna damage stimulus	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	-0.2405147068772	-0.940847812769752	0.555673144040891	0.861536528255015	45	TAF9B,KDM1A,SFRP2,MUC1,TPT1,RPS3,PSMD10,CHEK2,POLQ,TRIAP1,BRD4,MDM2,MIF,SIRT1,HELB
GO:0090218	positive regulation of lipid kinase activity	GO_POSITIVE_REGULATION_OF_LIPID_KINASE_ACTIVITY	0.267309090938172	0.935835937987475	0.556300194860775	0.861683034922464	32	PDGFB,ATG14,EEF1A2,FLT1,IRS1,ERBB4,TEK
GO:0002474	antigen processing and presentation of peptide antigen via mhc class i	GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I	0.219958969248201	0.950571523991329	0.556570454268664	0.861683034922464	89	SEC24C,PSMD11,PSMD2,PSMC6,TAP2,PSMC5,PSMB7,PSME4,HLA-B,HLA-H,PSMA8,PSMD8,PSMB10,CYBA,ABCB4,PSMD3,PSMB1,CD36,PSMA5,PSMB9,HLA-F,LNPEP,PSMD6,PSMB3,PSMB6,PSMD1,ACE,SEC24B,HLA-E,TAP1,PDIA3,PSME2
GO:0008637	apoptotic mitochondrial changes	GO_APOPTOTIC_MITOCHONDRIAL_CHANGES	0.242281506258829	0.941642249122818	0.556786852375667	0.861683034922464	51	RHOT2,BAD,MOAP1,CAMK2A,PPIF,SLC25A4,IFIT2,ERBB4,NDUFS1,SOD2,ATF2,BID,BAK1,BMF,PPP2CB,ATP2A1,BNIP3,ATG3,CDKN2A
GO:0006111	regulation of gluconeogenesis	GO_REGULATION_OF_GLUCONEOGENESIS	-0.269449617184779	-0.932859504181803	0.55712680896055	0.861683034922464	27	PTPN2,SESN2,DGAT2,FBP1,ADIPOQ,LEP
GO:0031346	positive regulation of cell projection organization	GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION	0.189916894536142	0.966519369085832	0.557654712687883	0.861683034922464	283	CPEB3,SHANK3,SF3A2,NLGN3,MARK2,RAPGEF1,CDKL5,NRP1,CBFA2T2,IL1RAPL1,LPAR3,PAFAH1B1,TIAM1,RAB21,TRPV2,NDRG4,P2RY2,VLDLR,MEGF8,SHANK1,NEDD4L,ZEB2,ARAP1,MACF1,MOB2,ARF1,HDAC4,GSK3B,RAPGEF2,OBSL1,DMD,RASAL1,ARHGAP35,PPP1R9A,GOLGA4,EPHA3,LIMK1,KAT2A,ITSN2,EZH2,DNM3,GPRC5B,FGFR1,EP300,FBXO31,WASL,SETX,FNBP1L,MTOR,IKBKB,SEMA5A,CAMK2B,CNTN1,VEGFA,APC,P2RX7,EPHA4,ZMYND8,C15orf62,IL2,L1CAM,HTT,BHLHB9,BCL11A,BCAS3,OPA1,CPNE9,MARCKS,NDNF,NTRK3,TGFB3,ITPKA,PLXNB3,ABL2
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY	-0.173922289256444	-0.975906959730748	0.55774957356385	0.861683034922464	475	ATP6V1C2,HAP1,EPHB6,SULF1,ESRP2,MAPK13,CD7,EFNB3,KDR,POLR2H,PDGFRL,FLRT3,FGF22,EFEMP1,PRKD1,AREG,NRG4,ATP6V1B1,PTPN2,MET,KLB,SS18,CTGF,BAIAP2L2,FGF7,ANGPT1,KRAS,FGFR2,EFNA5,ARPC5,CRIM1,MAPK12,ALK,FLRT2,FGF17,ACTG1,SH2D6,ACTR3,XBP1,DOK4,SGPL1,ATP6V0D1,FGF18,STAT3,ATP6V1H,SULF2,IGFBP1,NCF4,MST1R,CSF1,FLRT1,EGFR,POLR2K,ANGPT4,CD3EAP,BAIAP2,FGFBP1,EIF2AK3,FGF4,UBA52,GIT1,CASP3,RHOQ,GRB7,AP3S1,BDKRB2,FGF9,NAMPT,PAK3,PIGR,LTK,GTF2F1,HGF
GO:0002521	leukocyte differentiation	GO_LEUKOCYTE_DIFFERENTIATION	-0.182751543120817	-0.968464613981955	0.558055518661177	0.861683034922464	275	TCF3,TYRO3,TNFSF11,CCL19,KDM1A,BMP4,PTPN2,GATA3,CD79B,ANXA1,CLCF1,BATF3,ANXA2,PRTN3,PLA2G2D,FUT7,RAG2,CTNNB1,CEBPA,CSF1,IFNA14,SNX10,SH3PXD2A,L3MBTL3,IRF4,RIPK3,LEP,TNFSF9,CEBPG,MT1G,PPARG,CBFB,IFNE,RPL22,NKX2-3,RAG1,ZBTB1,CMTM7,ATP11C,ONECUT1,FAS,CLEC4E,IFNA16,BAX,KLF6,EPHA2,NKAP,FLT3,POU2F2,SEMA4A,MAFB,JUNB,IL25,OSTM1,CDC42,FAM20C,CEBPE,PTGER4,IFI16,RPS6,ABL1,SIRT1,PSEN1
GO:0032732	positive regulation of interleukin 1 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION	-0.251704941956744	-0.935578813585572	0.558103260021838	0.861683034922464	36	CCL3,GSDMD,CCL19,WNT5A,PYCARD,SAA1,NLRP3,NLRP12,IFNAR1,NOD1
GO:0021510	spinal cord development	GO_SPINAL_CORD_DEVELOPMENT	-0.207944882676651	-0.953740500778708	0.558265002970885	0.861683034922464	101	PAX7,LHX4,NKX6-1,GBX1,GDPD5,RFX4,SOX11,HOXC10,OLIG3,LHX5,MDGA2,EVX1,ISL2,MDGA1
GO:0016339	calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules	GO_CALCIUM_DEPENDENT_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES	-0.277319612729556	-0.931018926659931	0.558338450741293	0.861683034922464	24	NLGN1,PCDHB10,PCDHB5
GO:0033157	regulation of intracellular protein transport	GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT	0.186330622635603	0.967802840939324	0.558828625888061	0.861683034922464	342	PRKACA,PARL,PIK3R1,RBCK1,AKT2,FBXW7,PYDC2,GPHA2,ATPIF1,EDEM2,LRRK2,AKAP1,RANGAP1,ITGAX,SH3TC2,RNF31,VAMP2,C8orf4,SP100,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,SUFU,PKIA,GSK3B,AKAP6,JAK2,DDX58,SIAH3,CSF3,HUWE1,SIRT4,CYB5R1,CABP1,RGS20,IFI27,MBTPS1,PSMB7,AGTR2,KAT2A,UBR5,PDE2A,DERL3,SHH,SAE1,XPO4,NUCB1,EP300,ERBB4,PPP3R1,MTOR,IL18R1,YOD1,TNF,SEMA5A,TMEM173,EMD,ARIH2,PARK7,CDK1,PSMD8,BAG4,USP36,FAF1,ANK3,KANK1,MDFI,HYAL2,CD36,SMAD3,OAZ1,TPR,KCNN3,BAMBI,BCAS3,LITAF,RANBP3,NFKBIA,EGF,TLR4,TGFB3,FAM89B,MED1
GO:0032868	response to insulin	GO_RESPONSE_TO_INSULIN	0.197716631666632	0.960433061187054	0.558839591573303	0.861683034922464	193	PIK3R1,LPIN1,AKT2,PDGFB,HDAC9,HSD11B2,PPARA,GRB10,PPAT,VLDLR,OTC,TSC1,CPEB2,OPRK1,MAX,VAMP2,GHSR,SH2B2,PCSK9,RPE65,INPPL1,PIK3R3,GSK3B,PLN,PTPRN,IRS1,GCK,ATP6V0E2,TBC1D4,WDTC1,HADH,PRKCZ,MTOR,FOXO1,HMGCS2,RXRA,ATP6V0D2,SLC2A4,TRIB3,FABP3,SORT1,GOT1,GAB1,ATP6AP1,FOXO4,HADHA,PRKDC,APOBEC1,SLC27A1,YWHAG,ATP6V0C,HDAC5,ADM,PRKCQ
GO:0002456	t cell mediated immunity	GO_T_CELL_MEDIATED_IMMUNITY	-0.271516726790792	-0.93062868615556	0.559289972065196	0.861865705712012	26	RAET1E,CD55,GATA3
GO:0021885	forebrain cell migration	GO_FOREBRAIN_CELL_MIGRATION	-0.229356677985401	-0.943966678918955	0.559470162501707	0.861865705712012	57	TYRO3,RTN4,SEMA3A,FUT10,POU3F2,POU3F3,CTNNB1,SLIT3,EGFR,CDK5,FGF13
GO:0035813	regulation of renal sodium excretion	GO_REGULATION_OF_RENAL_SODIUM_EXCRETION	-0.282975863369345	-0.927722552381275	0.559957103149417	0.861910493684518	22	NPR1,ANPEP,TACR1,AGTR1,EDNRB,EDN1,PTGER4
GO:0043967	histone h4 acetylation	GO_HISTONE_H4_ACETYLATION	0.251477869672724	0.936749606043344	0.560108303249097	0.861910493684518	42	TRIM16,MEAF6,MCRS1,KAT7,KAT8,KAT2A,EP300,ING3,NAA50,MSL3P1,NCOA1,BRCA2,PER1,HCFC1,USP22,MSL2,OGT,NAA60,PHF20,EPC1
GO:0006607	nls bearing protein import into nucleus	GO_NLS_BEARING_PROTEIN_IMPORT_INTO_NUCLEUS	0.291526349985953	0.928576836880885	0.560531015816317	0.861910493684518	22	RANBP6,RERE,CBLB,KPNA4,KPNA3,KPNA6,NCKIPSD,KPNB1,NUP35
GO:0032456	endocytic recycling	GO_ENDOCYTIC_RECYCLING	0.294714784435214	0.927580966393351	0.561615266781094	0.861910493684518	21	EHD1,EHD4,VPS52,EPS15,RAB14,RAB11FIP3,DENND1B,STX6,EPG5
GO:0048592	eye morphogenesis	GO_EYE_MORPHOGENESIS	-0.200430971123157	-0.95636328065497	0.561672933248694	0.861910493684518	129	RBP4,IRX5,CDON,EFEMP1,MFAP2,BMP4,WNT5A,WNT2B,WNT9A,PRKCI,SOX11,PDE6C,ROM1,CTNNB1,GNAT1,STAT3,HIF1A,TULP1,RDH13,NRL,BCAR3,BAX,EPHA2,RS1,SHROOM2,PITX3,NKD1,GNGT1,AXIN1,PTF1A,STRA6,FOXL2
GO:0021532	neural tube patterning	GO_NEURAL_TUBE_PATTERNING	-0.256461597405689	-0.933301092514348	0.561943176277647	0.861910493684518	33	PAX7,TRAF3IP1,BMP4,FOXA1,GBX2,WDR19
GO:0008038	neuron recognition	GO_NEURON_RECOGNITION	-0.258183363329064	-0.932363182686571	0.56208556031137	0.861910493684518	32	CNR1,EFNB3,GAP43,RTN4,SEMA3A,ROBO2
GO:0001656	metanephros development	GO_METANEPHROS_DEVELOPMENT	-0.215714665391786	-0.949339699354787	0.562198560078287	0.861910493684518	80	PAX8,OSR1,WT1,RDH10,BMP4,GATA3,UMOD,POU3F3,CTNNB1,DLG5,WNT7B,ROBO2,ADIPOQ,IRX1,GDNF,CD34,WNT9B,PKD2,BASP1,IRX2,RET,FRAS1,BCL2
GO:0045191	regulation of isotype switching	GO_REGULATION_OF_ISOTYPE_SWITCHING	0.291137017236695	0.927336724716694	0.562243376111653	0.861910493684518	22	UNG,CD40,IL4,EXOSC3,IL2,BCL6,TNFSF4,PAXIP1,FOXP3
GO:0035337	fatty acyl coa metabolic process	GO_FATTY_ACYL_COA_METABOLIC_PROCESS	0.247360030208982	0.935609030118477	0.562339227572809	0.861910493684518	45	AGK,ACOT6,ACSM2A,ACOT2,ACOT11,ACSF2,ELOVL6,ACOT8,ACACB,GCDH
GO:0045666	positive regulation of neuron differentiation	GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION	0.189332554234293	0.964677225190456	0.562463963098213	0.861910493684518	286	CPEB3,SHANK3,SF3A2,NLGN3,MARK2,RAPGEF1,VWC2,CDKL5,NRP1,CBFA2T2,IL1RAPL1,ZEB1,LPAR3,PAFAH1B1,TIAM1,RAB21,TRPV2,NDRG4,P2RY2,VLDLR,GLI2,MEGF8,SHANK1,NEDD4L,TCF4,ZEB2,ADRA2C,MACF1,MOB2,ARF1,GSK3B,RAPGEF2,OBSL1,DMD,RASAL1,ARHGAP35,PPP1R9A,GOLGA4,EPHA3,LIMK1,ITSN2,VWC2L,EZH2,GPRC5B,FGFR1,EP300,FBXO31,SETX,MTOR,IKBKB,CCR2,SEMA5A,NKX2-5,CAMK2B,CNTN1,VEGFA,TRIM32,EPHA4,ZMYND8,IMPACT,IL2,NCOA1,L1CAM,BHLHB9,BCL11A,BCL6,NKX2-2,OPA1,EIF4G1,CPNE9,MARCKS,NDNF,PROX1,NTRK3,ITPKA,PLXNB3,ABL2,GATA2,NEGR1,MEF2C,SRF,TRPC6
GO:1902579	multi organism localization	GO_MULTI_ORGANISM_LOCALIZATION	0.233416849731354	0.940634242807975	0.562572000779824	0.861910493684518	61	POM121,NUP85,RAE1,TAP2,VPS37B,DDX39B,IFIT1,TCP1,NUP188,KPNA4,KPNA3,VPS37C,TPR,AAAS,POM121C,TSG101,VPS37A,NUP214,KPNB1,TAP1,NUP35,EPS15
GO:0070555	response to interleukin 1	GO_RESPONSE_TO_INTERLEUKIN_1	-0.207359305279191	-0.951916770489085	0.563081326019556	0.862055928562039	102	CHI3L1,PRKCA,PTGIS,CCL3,CCL19,CEBPB,PRKCI,SNCA,ANXA1,IRAK1,PYCARD,CCL21,RIPK2,HIF1A,IRAK3,FAS,SLC30A8,IL1R1,HNMT,YY2,CCL4,EDN1,CCL18,PTGER4
GO:0007612	learning	GO_LEARNING	0.209566892285085	0.951607569183192	0.56349935360958	0.862055928562039	119	SHANK3,NLGN3,NRXN1,DLG4,SLC24A2,DRD4,APP,ADRB2,NDRG4,HRH2,SHANK1,ATP1A2,DRD2,OPRK1,SLC6A1,HMGCR,GPR52,UCN,CLN8,NPS,NPTX2,MTOR,CREB1,RGS14
GO:0045601	regulation of endothelial cell differentiation	GO_REGULATION_OF_ENDOTHELIAL_CELL_DIFFERENTIATION	0.281801330692265	0.927775285194889	0.563909636453726	0.862055928562039	25	ATOH8,ROCK2,CDH5,IKBKB,TNF,PPP1R12A
GO:0070932	histone h3 deacetylation	GO_HISTONE_H3_DEACETYLATION	0.290792230844719	0.92623850269568	0.563937323930695	0.862055928562039	22	HDAC9,HDAC2,HDAC4,HDAC6,SFPQ,HDAC11,HDAC5,PER1,SIRT2,ATXN3,ELK4
GO:0001937	negative regulation of endothelial cell proliferation	GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	0.270022426104771	0.930626503936545	0.564142786786568	0.862055928562039	30	PTPRM,ATPIF1,ATOH8,ATP5A1,GJA1,CXCR3,DLL4
NA	chromatin silencing at rdna	GO_CHROMATIN_SILENCING_AT_RDNA	0.276680472782371	0.928681395400343	0.564346281339853	0.862055928562039	27	SUV39H1,HIST1H3G,HIST1H3B,HIST1H4F,RRP8,H3F3A,HIST1H3E,BAZ2A,HIST1H4A,SIRT2
GO:0048010	vascular endothelial growth factor receptor signaling pathway	GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	0.226581386701893	0.943143739223655	0.564824757512278	0.862055928562039	72	PIK3R1,CYFIP2,NRP1,MAPKAPK2,FLT1,ROCK2,ITGB3,MAPKAPK3,VEGFB,PXN,PDCD6,VEGFA,CYBA,HSPB1,SH2D2A,ELMO2,ELMO1
GO:0017144	drug metabolic process	GO_DRUG_METABOLIC_PROCESS	0.271933959760875	0.929398976489801	0.564933287093654	0.862055928562039	29	NR1I2,CYP2D6,CYP2E1,CYP2B6,FMO4
GO:0007492	endoderm development	GO_ENDODERM_DEVELOPMENT	-0.220024667104625	-0.944377419520132	0.565165165165165	0.862055928562039	70	VTN,LAMA3,LEO1,CTNNB1,PAX9,SMAD2,COL7A1,EXT1,ONECUT1,NODAL,DUSP2,LAMB3,COL12A1,INHBA,ARC,MMP14,COL11A1,NOG,GATA6,DUSP1,HSBP1,MMP9,EOMES,MIXL1,FN1,COL6A1
GO:0002292	t cell differentiation involved in immune response	GO_T_CELL_DIFFERENTIATION_INVOLVED_IN_IMMUNE_RESPONSE	0.27409478317549	0.928751145492056	0.565548139343513	0.862055928562039	28	RC3H2,ATP7A,TSC1,IL18R1,IL4,HMGB1
GO:0051588	regulation of neurotransmitter transport	GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT	0.235799939490941	0.937011749062243	0.565603595890411	0.862055928562039	57	GPM6B,DRD4,LRRK2,CAMK2A,CPLX3,ATP1A2,DRD2,STX1A,SNCG,RAB3GAP1,PPP1R9A,GRIK5,SYT12,SLC30A1,ATP2A2,PFN2,RAB3A,RIMS3,MEF2C
GO:1990778	protein localization to cell periphery	GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY	0.204040104581051	0.954156216140299	0.565740209802004	0.862055928562039	146	ZFYVE27,P2RY1,RILPL1,AKT2,ANK2,KIF13A,TNIK,TMEM88,LRP6,RAPGEF6,ROCK2,CLIP1,PPIL2,SYTL2,VAMP2,CDH2,MACF1,RAPGEF2,CAV3,PKP2,GOLGA4,TUB,NFASC,PRKCZ,RAMP3,IKBKB,TNF,BAG4,PTCH1,TSPAN17,EFR3B,ANK3,RDX,FAM126A,LAMA5,TTC7B,CALCR,SCP2,FLOT1,EMP2,TMEM150A,JUP,EFR3A,TSPAN14,PACSIN1,SPTBN1,ACTN2,GOLPH3,CLASP2,TTC7A,ANK1,RAB26,PACS2,BBS2
NA	positive regulation of chromatin modification	GO_POSITIVE_REGULATION_OF_CHROMATIN_MODIFICATION	0.222596734415723	0.944286061442126	0.566175568908432	0.86232894341438	80	TET1,SMARCB1,JARID2,RNF40,ZNF304,PAF1,AKAP8,UBE2N,EED,SETDB1,KAT2A,EP300,VEGFA,DMRTC2,WBP2,TPR,BCL6,CHTOP,AKAP8L,GCG,PAXIP1,RNF20,SIN3A,SART3,PPARGC1A,RPS6KA5,FOXP3,TRIM28,ATM,MAPK3,OGT,PIWIL2,C6orf89,MTF2
GO:0002367	cytokine production involved in immune response	GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	-0.300825286383799	-0.920015245069371	0.567158368300385	0.863129821893391	17	CD55,TLR2,DLG1,SIRT1,GAS6
GO:1903830	magnesium ion transmembrane transport	GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORT	-0.311199793249288	-0.916784392870994	0.567214250156916	0.863129821893391	15	SLC41A2,CLDN16,NIPAL4,NIPAL2
GO:0030811	regulation of nucleotide catabolic process	GO_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS	0.263827920473349	0.930097565706135	0.568203352769679	0.863744411414211	33	PPARA,PGAM1,HDAC4,PRKAA2,GCK,EGLN1,NCOR1,P2RX7,DDIT4,CBFA2T3,PRKAG1,PPARGC1A,ENTPD5,OGT,INSR
GO:0010883	regulation of lipid storage	GO_REGULATION_OF_LIPID_STORAGE	-0.251925081680021	-0.930173883574161	0.568323257467994	0.863744411414211	35	C3,MEST,PTPN2,CIDEA,LPL,LEP,PPARG,ABCA1,NR1H3,OSBPL11,ABCG1,OSBPL8
GO:0030521	androgen receptor signaling pathway	GO_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY	0.255613417179668	0.931599864605757	0.568387959382792	0.863744411414211	38	RNF14,NKX3-1,MED24,MED12,AR,MED17,THRAP3,FHL2,NCOA3,NCOA1,MED1,PPARGC1A,UBE3A,GRIP1,RNF4
GO:0043534	blood vessel endothelial cell migration	GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.293184593543593	0.92276486614668	0.568979200118118	0.864055720891494	21	AMOT,NRP1,VEGFA,EMP2,SRF,GPLD1,EFNB2
GO:0002579	positive regulation of antigen processing and presentation	GO_POSITIVE_REGULATION_OF_ANTIGEN_PROCESSING_AND_PRESENTATION	-0.305344404916054	-0.917483100496657	0.569106219018551	0.864055720891494	16	CCL19,PYCARD,CCL21,NOD1,ABCB5,ABCB1
GO:0032922	circadian regulation of gene expression	GO_CIRCADIAN_REGULATION_OF_GENE_EXPRESSION	0.240457631095283	0.934553644063188	0.569479752228866	0.86423302344561	51	HDAC2,PPARA,DRD2,ZFHX3,USP2,KDM5A,MAGED1,PPP1CB,RAI1,MTA1,PER1,PER3,NPAS2,PPARGC1A,HNRNPU,PPP1CC,DRD3,CRY2,NCOA2,OGT
GO:0000737	dna catabolic process endonucleolytic	GO_DNA_CATABOLIC_PROCESS_ENDONUCLEOLYTIC	0.300851309491014	0.920640299366196	0.569879919946631	0.864450568066859	19	FBXO18,SPO11,DICER1,DNASE2B,CECR2,HMGB1,ENDOG,H1F0,KPNB1,SETMAR
GO:0044065	regulation of respiratory system process	GO_REGULATION_OF_RESPIRATORY_SYSTEM_PROCESS	0.319301970041691	0.917503825885245	0.570419524526478	0.86487933313339	15	NLGN3,ATP1A2,MTG1,FTO,NLGN2,PHOX2B,GLRA1
GO:1901571	fatty acid derivative transport	GO_FATTY_ACID_DERIVATIVE_TRANSPORT	0.297019190628284	0.921978759938843	0.570688378978534	0.864884689884481	20	SLCO3A1,DRD4,DRD2,PLA2G5,ABCC2
GO:0097154	gabaergic neuron differentiation	GO_GABAERGIC_NEURON_DIFFERENTIATION	-0.310340435027533	-0.914252751710938	0.570936952145965	0.864884689884481	15	DLX1,HELT
GO:0034109	homotypic cell cell adhesion	GO_HOMOTYPIC_CELL_CELL_ADHESION	0.243146001945387	0.932422664795769	0.571695738176587	0.865263845059309	48	GNAS,MYL12A,CTNNA3,ITGB3,PKP2,MYL9,ITGA2B,HSPB1,METAP1,TSPAN32,JUP,DSP,PIK3CB,VCL,FGG,PIK3CG,HBB
GO:0032781	positive regulation of atpase activity	GO_POSITIVE_REGULATION_OF_ATPASE_ACTIVITY	0.253870113677289	0.930252918167254	0.571826200115674	0.865263845059309	39	UHRF1,ADRB2,RYR2,MYBPC3,AHSA2,TNNT2,SUMO1,PFN2,DNAJC9,RAB3A,CHTOP,MYL4,ATP1B2,AHSA1,HNRNPU,DNM2
GO:0051489	regulation of filopodium assembly	GO_REGULATION_OF_FILOPODIUM_ASSEMBLY	-0.252847173573662	-0.926783898101301	0.571958424021676	0.865263845059309	34	NLGN1,AGRN,TGFBR1,GPM6A,GAP43,CCL21,RHOQ,DPYSL3,RALA,RAB17,CDC42
GO:0036075	replacement ossification	GO_REPLACEMENT_OSSIFICATION	-0.272090751009415	-0.922965780469367	0.572542901716069	0.86540037515252	25	NAB2,BMP4,ALPL,FGF18
GO:0010718	positive regulation of epithelial to mesenchymal transition	GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION	0.264627361052376	0.926447333977433	0.572562874469596	0.86540037515252	32	HDAC2,BCL9L,TGFBR2,GLIPR2,EZH2,GCNT2,SMAD3,BAMBI,TGFB3,TWIST1,OLFM1
GO:0030879	mammary gland development	GO_MAMMARY_GLAND_DEVELOPMENT	0.212073562265335	0.945618102947448	0.573064967627814	0.86577050315764	107	LRP5,AKT2,ATP7A,TBX2,STAT5B,PPAT,ESR1,CCND1,GLI2,IRF6,BTRC,JAK2,TGFBR2,ERBB4,CREB1,NCOR1,MAPK1,VEGFA,PTCH1,USF2,SOX9,NCOA1,CAD,DHODH,EGF,CSN2,CSN3,TGFB3,TBX3,MSX1,HOXB9,MED1,XDH
GO:0090398	cellular senescence	GO_CELLULAR_SENESCENCE	0.270288916589149	0.92377665024034	0.5738587621151	0.865987096597821	29	TBX2,HMGA1,KAT6A,MAPKAPK5,ULK3,OPA1,TBX3,SRF,NSMCE2,CDKN2A
GO:0035268	protein mannosylation	GO_PROTEIN_MANNOSYLATION	0.304019272945763	0.917223601939597	0.574075793304492	0.865987096597821	18	POMT1,DPY19L2,POMT2,FKRP,DPY19L4,SDF2L1,DPM2
GO:0030010	establishment of cell polarity	GO_ESTABLISHMENT_OF_CELL_POLARITY	-0.212515245715517	-0.943994581650748	0.574106934391782	0.865987096597821	84	EZR,CCL19,CYP26B1,WNT5A,WWC1,PTK7,PRKCI,MPP7,FOXF1,FRMD4B,BRSK2,CCL21,RAB10,WDR43,MPP5,FGF13,FERMT1,DOCK7,MSN,FBF1,ZW10,LLGL1,MOS,SIPA1L3,RICTOR,WNT7A,NDC80,RAB11FIP2,LLGL2,FSCN1,PARD3,DYNLT1
GO:0034329	cell junction assembly	GO_CELL_JUNCTION_ASSEMBLY	-0.201027320675309	-0.950898243149193	0.574356981517014	0.865987096597821	122	CLDN1,PRKCA,PARD6B,PIP5K1A,OCLN,LAMA3,LAMC2,LSR,GRHL2,PRKCI,MPP7,MARVELD2,ACTG1,CTNNB1,DLG5,WHAMM,RAB13,RHOD,MPP5,KRT14,PDPK1,FBF1,ZNF703,F11R,RHOA,LAMB3,DLG1,UGT8,ITGB4,BCL2,PLEC,HEG1,RHOC,ACTN1,RCC2,FSCN1,TRIP6,PARD3,PTK2B
GO:0090329	regulation of dna dependent dna replication	GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION	0.252120710225722	0.928966547962446	0.57473984679867	0.865987096597821	40	FBXW7,FBXO18,ZRANB3,DACH1,E2F8,SMC1A,LIG3,RFC3,WRNIP1,ATRX,MRE11A,TIPIN,BRCA2
GO:0010470	regulation of gastrulation	GO_REGULATION_OF_GASTRULATION	-0.26220839104666	-0.923959134783382	0.574765011611191	0.865987096597821	29	OSR1,SFRP2,OTX2,KLF4,ADIPOQ
GO:0038127	erbb signaling pathway	GO_ERBB_SIGNALING_PATHWAY	-0.217676162896624	-0.941843174567646	0.575009257544899	0.865987096597821	73	EFEMP1,AREG,NRG4,KRAS,EGFR,UBA52,GRB7,PIGR,MVP,PDPK1,HSP90AA1,CPNE3,SHC3,MATK,UBB,RASSF2,ABL1,REPS2,NRG1,HRAS,ARF4,PTK2B,NRAS,FES
GO:0072507	divalent inorganic cation homeostasis	GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS	0.186471725653378	0.962105130601704	0.575885489399518	0.866918853899274	321	P2RY1,CCL1,XK,PRKACA,TMC8,MICU1,TRPM4,OPRL1,ANK2,ITPR1,DLG4,SLC24A2,PYGM,LPAR3,DRD4,LRP6,NPY1R,TRPV1,APP,DMPK,P2RY2,CACNA2D1,ESR1,ANXA6,RYR2,TPCN1,XCL1,ATP1A2,DRD2,HRC,SLC24A1,GIPR,CNNM4,GJA1,GLP1R,PLCE1,JAK2,CAV3,CYP27B1,CXCR3,PLN,STC2,ADCY5,GCK,SLC8A1,CD40,TNNI3,TRPM1,SLC39A14,CACNA1C,GNAT2,KCNA5,CCR2,TRPC5,S1PR1,TRIM24,SYPL2,P2RX7,ATP2C2,GRINA,ANK3,NMUR2,CCR8,IL2,CD38,SLC30A1,HMGB1,CD36,CCL23,TRDN,GALR1,PTH,CNNM2,VAPB,ATP2A2,NPFF,JPH2,PRKCE,CALCR,TRPC7,LPAR2,ABL2,GATA2,BAK1,PTH1R,CALCB,ADM,ATP13A5,TRPC6,IBTK
GO:0002832	negative regulation of response to biotic stimulus	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS	-0.268597765401697	-0.92062389111188	0.57616083408486	0.866945626968994	26	TARBP2,TRAF3IP1,HTRA1,TRIM38,DEFB114,IL2RA,TRIB1,PRDM1,LTF
GO:0046825	regulation of protein export from nucleus	GO_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS	0.262386948155127	0.925017569460766	0.577095481049563	0.867639255382702	33	PRKACA,RANGAP1,SP100,GSK3B,IFI27,XPO4,EMD,PARK7,TPR,RANBP3
GO:0044262	cellular carbohydrate metabolic process	GO_CELLULAR_CARBOHYDRATE_METABOLIC_PROCESS	0.205773518956656	0.946651930013776	0.577137341890038	0.867639255382702	130	AKT2,MOGAT1,PYGB,PYGM,PGM5,CALM3,PHKG1,GYS1,IMPA2,GSK3B,PTEN,INPP1,PFKM,GCK,HAS3,STK40,PPP1R3A,CALM1,PPP1R3B,PFKFB4,IDH2,PHKA2,PHKB,GANC,HK3,NAGK,GNPTAB,GALK1,IDH1,GYG1,PPP1CB,GOT1,PPP1R3E,EPM2A,PRKAG3,PHKG2,ITPKA,MTMR2,COQ2,PPP1R3C
GO:0006883	cellular sodium ion homeostasis	GO_CELLULAR_SODIUM_ION_HOMEOSTASIS	-0.298205014787167	-0.912001657368341	0.578275727819354	0.868962544571404	17	SGK2,TMPRSS3,SGK1
GO:1901605	alpha amino acid metabolic process	GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS	0.195292593450672	0.953901514067753	0.578752947772885	0.869291576172928	201	IVD,ATP7A,HIBCH,STAT5B,DMGDH,ATPIF1,MCCC2,CKMT2,DDO,AMT,AUH,ALDH7A1,PPAT,OTC,CKB,DLD,THNSL1,MTR,THNSL2,TYR,MTHFR,OGDH,HAAO,FPGS,ASRGL1,NMNAT3,SIRT4,SARDH,PSPH,IDO1,CKM,EGLN1,GLUD1,GOT2,ADSSL1,GATM,ART4,SLC25A32,SLC6A8,PRODH2,EIF2B4,GOT1,HOGA1,GCDH,ASNS,SMS,GLUD2,CAD,DLST,SHMT2,NMNAT2,TH,NIT2,NOX4,PIPOX,ACMSD,CTH,MUT,PLOD1,QDPR,SEPSECS,CRYM,ARG1,NOS2
GO:0015698	inorganic anion transport	GO_INORGANIC_ANION_TRANSPORT	0.206229355038397	0.945173601981047	0.579879452796966	0.870563697124463	126	SLC17A3,TTYH2,BEST3,ANO2,SLC26A4,CLCN6,CLCN4,FXYD3,SLC4A3,SLC25A3,FXYD1,SLC12A6,ANO1,SLC26A5,SLC4A10,SLC20A2,SLC17A1,IP6K2,SLC34A3,BEST2,SLC26A7,SLC12A2,SLC26A3,GLRA3,NMUR2,BSND,SLC12A7,BEST4,SLC17A4,APOL1,GABRA3,ENPP3,ANO5
GO:0009408	response to heat	GO_RESPONSE_TO_HEAT	0.220178479428116	0.937886343261326	0.580117163591851	0.870563697124463	82	HSPB7,EIF2B5,HDAC2,TRPV2,C8orf4,OSM,CETN1,ABCC2,FGF1,DNAJB4,ANO1,DNAJA3,STAC,DNAJA2,PDCD6,MICA,TFEC,SOD1
GO:0046503	glycerolipid catabolic process	GO_GLYCEROLIPID_CATABOLIC_PROCESS	0.256618269323402	0.923001252540036	0.581297052154195	0.87125156911128	36	APOC3,PLA2G4C,FABP9,ABHD2,FABP7,ABHD6,PLA2G15,MGLL,SMPD4,FABP3,GPCPD1,PNPLA6,INPP5F,APOA5,FABP12,PNPLA2
GO:0034104	negative regulation of tissue remodeling	GO_NEGATIVE_REGULATION_OF_TISSUE_REMODELING	0.311726624410208	0.910844941880564	0.581414366694545	0.87125156911128	16	AGT,ABR,INPP5D,P2RX7,CD38
GO:0019915	lipid storage	GO_LIPID_STORAGE	-0.273092553273891	-0.916827819443944	0.581608035792613	0.87125156911128	24	PLIN2,CIDEA,ANGPTL3,DGAT2,ACVR1C
GO:0008089	anterograde axonal transport	GO_ANTEROGRADE_AXONAL_TRANSPORT	-0.285641813595202	-0.912786296854745	0.58161089595753	0.87125156911128	20	HAP1,AP3M1,AP3S1,KIF4A,SNAPIN,SPAST,BLOC1S3
NA	positive regulation of glucose transport	GO_POSITIVE_REGULATION_OF_GLUCOSE_TRANSPORT	-0.243104719579664	-0.925737025230241	0.582172452407615	0.871704837546277	40	C3,ITLN1,FFAR3,PRKCI,NR4A3,ADIPOQ,RHOQ,RARRES2
GO:0015918	sterol transport	GO_STEROL_TRANSPORT	-0.23693476388696	-0.926843756319571	0.582580892121321	0.871928538408345	45	CFTR,APOA2,APOC1,LIPC,NPC1L1,ABCG4,STAR,ABCA7,ABCA1,APOM,ABCG1
GO:1904018	positive regulation of vasculature development	GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	-0.20046681606744	-0.946888410733959	0.584063919178182	0.87375962309056	121	CHI3L1,CMA1,PRKCA,PTGIS,C3,ANXA3,KDR,AQP1,PRKD1,WNT5A,SFRP2
GO:0008217	regulation of blood pressure	GO_REGULATION_OF_BLOOD_PRESSURE	0.200070254197033	0.948652219221236	0.584545104666923	0.874021847099279	161	LRP5,AGT,OPRL1,PDGFB,ADRB1,SERPINF2,NPY1R,HSD11B2,ADRB2,PPARA,WNK1,ATP1A2,DRD2,RENBP,ADH5,TACR3,GJA1,GLP1R,GUCY1A3,UCN,NPR2,AGTR2,TNNI3,GNB3,NCALD,SLC4A5,GJA5,ACE2,SOD2,NPY,CACNA1B,CYBA,ENG,SOD1
GO:0055083	monovalent inorganic anion homeostasis	GO_MONOVALENT_INORGANIC_ANION_HOMEOSTASIS	-0.296854144949987	-0.907870286434567	0.584786088160228	0.874021847099279	17	SLC34A1,CA12
GO:2001267	regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	-0.278019894544725	-0.911474650554052	0.586373684095336	0.874021847099279	22	RIPK1,NLE1,TRADD,PLAUR,FAS,BAX
GO:0090317	negative regulation of intracellular protein transport	GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT	0.217156644057183	0.93676258344602	0.586579144394338	0.874021847099279	88	PYDC2,LRRK2,AKAP1,RANGAP1,SP100,SUFU,PKIA,GSK3B,SIAH3,SIRT4,CABP1,PDE2A,DERL3,MTOR,YOD1,EMD,PARK7,BAG4,FAF1,MDFI,CD36,LITAF,NFKBIA,FAM89B
GO:0046850	regulation of bone remodeling	GO_REGULATION_OF_BONE_REMODELING	0.255771424841918	0.919955333326345	0.586721088435374	0.874021847099279	36	LRP5,ITGB3,GJA1,SYT7,INPP5D,S1PR1,CA2,P2RX7,CD38,ATP6AP1
GO:2000242	negative regulation of reproductive process	GO_NEGATIVE_REGULATION_OF_REPRODUCTIVE_PROCESS	-0.231150655805681	-0.929316083608264	0.586897426603842	0.874021847099279	51	TIMP1,SULF1,WT1,BMP4,WNT5A,DMRT1,ACVR1C,FBXO5,ASTL,NODAL,GPR149,MOS,NANOS2,SERPINF1,FBXO43,RPS6KA2,DUSP1,SPINK13,ZP4,STRA8,BMP7,IGF1
GO:0001667	ameboidal type cell migration	GO_AMEBOIDAL_TYPE_CELL_MIGRATION	-0.19490882305615	-0.949777086017691	0.586947959233913	0.874021847099279	147	SEMA3F,SEMA3C,SCG2,DPP4,PIP5K1A,KDR,TGFBR1,WNT5A,T,FAP,GBX2,SEMA3A,SEMA3B,ACVR1,SGPL1,HIF1A,ANLN,RAB13,SEMA3D,NOV,GDNF,EDNRB,FERMT1,CORO1C,SEMA3E,KRT16,SEMA4B,RHOA,SEMA4A,NODAL,SRGAP2
GO:0071260	cellular response to mechanical stimulus	GO_CELLULAR_RESPONSE_TO_MECHANICAL_STIMULUS	0.221950779242085	0.933006252905026	0.586964533281856	0.874021847099279	76	AGT,BAD,HABP4,ATP1A2,KCNJ2,GJA1,HDAC4,BAG3,GSK3B,CD40,PDE2A,TNFRSF10B,CASP8AP2,MMP7,IRF1,CYBA,GADD45A,SOX9
GO:1903306	negative regulation of regulated secretory pathway	GO_NEGATIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY	0.30092819500411	0.907897845660901	0.587240284456988	0.874021847099279	18	CEACAM1,ABR,REST,CD300A,CCR2
GO:0006862	nucleotide transport	GO_NUCLEOTIDE_TRANSPORT	0.286328494514938	0.912020500919928	0.587302756347701	0.874021847099279	22	SLC25A17,SLC25A36,GJA1,SLC35B1,P2RX7
GO:0034219	carbohydrate transmembrane transport	GO_CARBOHYDRATE_TRANSMEMBRANE_TRANSPORT	-0.271968239442757	-0.913053266876283	0.587573471357137	0.874021847099279	24	SLC5A9,SLC35E1,SLC2A5,SLC2A10,SLC5A2,SLC2A2,SLC2A1
GO:0007631	feeding behavior	GO_FEEDING_BEHAVIOR	0.217058516804338	0.936339285603668	0.587676074730556	0.874021847099279	88	P2RY1,AGT,USP46,OPRL1,BBS12,NPY1R,APP,HAND2,DRD2,OPRK1,GHSR,UCN,DACH1,NPY5R,ACE2,NPY,CNTFR,NMUR2,NPY6R,UBR3,GIGYF2,HCRTR1,TH,NEGR1,GCG
GO:0071634	regulation of transforming growth factor beta production	GO_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_PRODUCTION	0.280050257133484	0.912551596073627	0.587968238797192	0.874021847099279	24	SERPINF2,XCL1,CX3CL1,CREB1,ATF2,WNT11,SMAD3
GO:0061028	establishment of endothelial barrier	GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER	0.270033499612037	0.914989768066241	0.588461186797111	0.874021847099279	28	RAPGEF1,PPP1R16B,RAPGEF6,RAPGEF2,RAB1B,PDE2A,RAP2C,ENG,RDX
GO:0097150	neuronal stem cell population maintenance	GO_NEURONAL_STEM_CELL_POPULATION_MAINTENANCE	-0.291868204758877	-0.906383244839775	0.588991223317803	0.874021847099279	18	MMP24,SS18,FUT10,PCM1,FOXO3
GO:1900015	regulation of cytokine production involved in inflammatory response	GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_INFLAMMATORY_RESPONSE	-0.295819799908409	-0.904706944621276	0.58911190898473	0.874021847099279	17	IL17B,LEP,IL17RC,IL17F
GO:0070482	response to oxygen levels	GO_RESPONSE_TO_OXYGEN_LEVELS	0.18742295741431	0.95681146387483	0.589276584867076	0.874021847099279	290	CHAT,BAD,PPARD,PDGFB,EPAS1,WTIP,ITPR1,STAT5B,TXN2,HDAC2,PYGM,FLT1,HSD11B2,ADRB2,PPARA,VLDLR,CREBBP,TSC1,RYR2,CPEB2,DRD2,HIPK2,SUV39H1,MTHFR,PINK1,NKX3-1,PTEN,SIRT4,HP1BP3,STC2,SLC8A1,EGLN1,CX3CL1,RAF1,ALAD,EP300,POLG,ADA,LONP1,MTOR,FOXO1,KCNA5,CREB1,TEK,CDKN1B,KCNMA1,VEGFA,ALKBH5,SLC2A4,ETS1,ENG,LIMD1,PLAU,FAM162A,CUL2,CD38,SMAD3,ENDOG,PRKCE,HMOX2,PDLIM1,NDNF,TGFB3,CYP1A1,DDIT4,TH,ADM,CBFA2T3,PRKCQ,NOX4,PSEN2,SRF,TWIST1,TRPC6,LCT,AIFM1,TGFBR3,P2RX2,PGF,NARFL,MT3,CYGB,PLOD1,PDK3,USF1,UTS2,MYOCD,SOD3,MDM4,BNIP3,SIRT2
GO:0034332	adherens junction organization	GO_ADHERENS_JUNCTION_ORGANIZATION	0.230007561240466	0.926895331063467	0.589511369476986	0.874021847099279	61	TAOK2,TESK2,TBCD,CDH10,DLC1,CDH2,CDH5,CDH6,CTNNA1,PTPRK,PKP2
GO:1901031	regulation of response to reactive oxygen species	GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES	-0.254196334039031	-0.91796504614366	0.589762923865073	0.874021847099279	32	HP,MET,SNCA,SESN2,NR4A3,PYCR1,DHFR,HGF,HEBP2,NFE2L2
GO:0010842	retina layer formation	GO_RETINA_LAYER_FORMATION	0.285811719273747	0.910374455823605	0.58991732798144	0.874021847099279	22	PTPRM,PROM1,HIPK2,TSPAN12,SDK1,LHX1
GO:0051048	negative regulation of secretion	GO_NEGATIVE_REGULATION_OF_SECRETION	0.196536855105718	0.94811945186271	0.590443855581318	0.874021847099279	182	P2RY1,RSAD2,BMP8A,IL1RAPL1,PYDC2,PDE8B,DRD4,NPY1R,WNK1,DRD2,OPRK1,GHSR,CEACAM1,ADRA2C,ABR,SERGEF,HMGCR,OSM,PDE4C,REST,SIRT4,UCN,CD300A,IRS1,GCK,PPP1R9A,AGTR2,HADH,CX3CL1,ADA,GBP1,CCR2,TNF,GABBR1,NPY5R
GO:0043576	regulation of respiratory gaseous exchange	GO_REGULATION_OF_RESPIRATORY_GASEOUS_EXCHANGE	0.28896249138611	0.909476284079257	0.590517320930919	0.874021847099279	21	NLGN3,ATP1A2,MTG1,FTO,PASK,NLGN2,PHOX2B,GLRA1,PHOX2A,GRIN1,MECP2
GO:0045190	isotype switching	GO_ISOTYPE_SWITCHING	0.309398626576344	0.904042683473229	0.591580708112629	0.874021847099279	16	HSPD1,ERCC1,AICDA,EXOSC3,RNF168,MLH1,EXO1
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	GO_REGULATION_OF_INTRACELLULAR_ESTROGEN_RECEPTOR_SIGNALING_PATHWAY	0.285244636478368	0.908568169879272	0.592605549520355	0.874021847099279	22	CRIPAK,DDX17,KANK2,CYP7B1,ZNF366,MED1,CNOT1
GO:0033032	regulation of myeloid cell apoptotic process	GO_REGULATION_OF_MYELOID_CELL_APOPTOTIC_PROCESS	-0.273874380408976	-0.908393018049646	0.592625109745391	0.874021847099279	23	ANXA1,IRF7,HCAR2,ADIPOQ,CLEC5A,MIF,SIRT1,BCL2
NA	single organism cell adhesion	GO_SINGLE_ORGANISM_CELL_ADHESION	-0.173869833348502	-0.966411653391453	0.592973436161097	0.874021847099279	431	PDPN,CDH7,TYRO3,DPP4,EZR,ZAN,CCL19,CD7,MMP24,NLGN1,CYP26B1,ANXA9,PTPN2,TNFSF14,NPNT,ELF4,GATA3,CEBPB,FOXF1,CYR61,CAMSAP3,CDSN,GCNT1,CERCAM,ANXA1,UMOD,SRPX2,ACTG1,PODXL2,TNXB,PLA2G2D,KIRREL,FUT7,RAG2,CTNNB1,PARVA,CCL21,DLG5,RIPK2,STXBP3,IFNA14,ANTXR1,EGFR,WNT7B,IRF4,RIPK3,ICAM4,CDH3,LEP,LILRB2,NOV,S100A9,IFNE,NLGN4Y,RPL22,NKX2-3,RAG1,ZBTB1,EIF2AK4,MPZL2,LAT,PTPRU,FAS,CDH1,APBB1IP,CLEC4E,IFNA16,CTNND2,CD34,STXBP1,IFNAR1,RAP2B,CEP41,BAX,ADAM9,MSN,NKAP,ASTN1,NRCAM,TTYH1,NPHP1,SEMA4A,MAFB,SRGAP2,CDC42,CLIC1,CEACAM5,PTGER4,DLG1,THBS4,RPS6,ABL1,PSEN1,RET,CD276
GO:0035094	response to nicotine	GO_RESPONSE_TO_NICOTINE	-0.234612353126466	-0.922558809483366	0.592984987151165	0.874021847099279	46	CNR1,NKX6-1,TACR1,SLC6A3,STAR,CASP3,CHRNB2,RAPGEF3,KCNK1,CHRNG,ABAT,EDN1
GO:0032722	positive regulation of chemokine production	GO_POSITIVE_REGULATION_OF_CHEMOKINE_PRODUCTION	-0.232605789402604	-0.923379392627962	0.593124887367093	0.874021847099279	48	FFAR3,WNT5A,PYCARD,RIPK2,LPL,HIF1A,ADIPOQ,C5,TLR9,ADCYAP1,TLR2,MIF
GO:0043001	golgi to plasma membrane protein transport	GO_GOLGI_TO_PLASMA_MEMBRANE_PROTEIN_TRANSPORT	-0.270950600930307	-0.909636845274277	0.593473111676463	0.874021847099279	24	RAB31,AMN,KRT18,RAB10,GOLGA7,GCC2
GO:0042326	negative regulation of phosphorylation	GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION	0.181877554097964	0.959117070015548	0.593542687085374	0.874021847099279	397	LRP5,ADAR,RAPGEF1,CDK5RAP1,FLCN,NPM1,TRIB2,ATG14,RGS3,LRP6,PAFAH1B1,PPARA,CRIPAK,IGFBP3,LRRK2,CALM3,GRB10,PIN1,APOC3,TAOK3,WNK1,EPHA1,TSC2,PPIF,ZGPAT,WNK2,PINK1,ADARB1,INPP5J,HMGCR,HDAC4,PKIA,GSK3B,CAV3,PTEN,CHORDC1,FAM129A,CDK5RAP3,DMD,PRKAR1A,MLLT1,CD300A,LRTM1,DNAJA3,CEP85,PPP5C,LATS1,LAX1,CALM1,PRKCZ,FBXO31,COX11,MTOR,FOXO1,GBP1,DUSP19,DUSP21,CDKN1B,RGS14,PARK7,SOCS4,RPS6KA6,NCOR1,MECOM,PIK3IP1,ATXN7,SH3BP5L,TIMP3,PKN1,APC,P2RX7,ENG,PAX6,HSPB1,TRIB3,GADD45A,DUSP3,LEMD2,PBK,LRRTM3,RHOH,IMPACT,AKT1S1,IL2,HYAL2,SMAD7,SMAD3,DUSP7,HEXIM2,LRRK1,PRKDC,CHAD,CNKSR3,UBE2B,CTDSP2,NTRK3,TLR4,DUSP4,PRDX3,INPP5F,YWHAG,XDH,DDIT4,PAQR3,BAK1,DUSP26,CBFA2T3,CRYBA1,PPP1R1C,NR2F2,TWIST1,IBTK,PKIB,HSPH1
GO:1901215	negative regulation of neuron death	GO_NEGATIVE_REGULATION_OF_NEURON_DEATH	-0.192120851618576	-0.948729039485791	0.593722820009443	0.874021847099279	161	GDF5,TYRO3,DLX1,TOX3,MAP2K4,ANGPT1,KRAS,CEBPB,PRKCI,SNCA,CLCF1,CTNNB1,NONO,STAT3,TP73,NR4A3,STAR,HIF1A,CDK5,C5AR1,IKBKG,SORL1,GDNF,CD34,XRCC2,STXBP1,BAX,GRIK2,CPEB4,F2R,CLN3,ALKBH1,LRP1,BTG2,SIRT1,PSEN1,SERPINF1,GABRB2,MAP3K12,BCL2,UBE2V2,ISL1,HRAS,ITSN1,JUN
GO:0051447	negative regulation of meiotic cell cycle	GO_NEGATIVE_REGULATION_OF_MEIOTIC_CELL_CYCLE	0.295800626509601	0.905184616956576	0.594044177599881	0.874021847099279	19	PRKACA,OSM,PRKAR1A,NPR2
GO:0030183	b cell differentiation	GO_B_CELL_DIFFERENTIATION	-0.212601555572387	-0.935639199508663	0.594072555278548	0.874021847099279	80	TCF3,PTPN2,CD79B,CLCF1,RAG2,IFNA14,CEBPG,IFNE,NKX2-3,RAG1,ZBTB1,CMTM7,ATP11C,ONECUT1,IFNA16,BAX,KLF6,FLT3,POU2F2
GO:0002323	natural killer cell activation involved in immune response	GO_NATURAL_KILLER_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.278892557221199	0.90877919852776	0.594088887255082	0.874021847099279	24	UNC13D,KLRF2,VAMP2
GO:0051602	response to electrical stimulus	GO_RESPONSE_TO_ELECTRICAL_STIMULUS	0.247779461137527	0.918066927972091	0.594147398843931	0.874021847099279	41	EEF1A2,KCNJ3,RPE65,REST,ADSSL1,BRD1,P2RX7,S100A13,PSMB9,RAB3A,TH,TRIM63,PPARGC1A,OXT,RPS6KB1
GO:0050673	epithelial cell proliferation	GO_EPITHELIAL_CELL_PROLIFERATION	0.21800898455381	0.932142974236453	0.59417197229413	0.874021847099279	84	BAD,PPARD,IGFBP3,ESR1,BMPER,CCND1,IRF6,PRKX,NKX3-1,FABP7,BTRC,NCSTN,SHH,MTSS1,ESR2,CDH13,TNF,SEMA5A,TEK,MAPK1,PTCH1,SOX9,HMGB1,LGR5,BTBD10,FOXN1,PROX1,MED1,MEF2C,PIK3CB,COL8A2,EREG,IGFBP5
GO:0009308	amine metabolic process	GO_AMINE_METABOLIC_PROCESS	-0.199530296218479	-0.943817026918637	0.594248658101183	0.874021847099279	122	SMPDL3B,PLA2G2A,CHDH,HDC,TPH1,APOA2,SMPD3,LIPC,BCHE,FGF7,PEMT,SMPDL3A,PLA2G16,SMPD2,PLA2G2D,DDC,SAT1,PLA2G4F,SGMS2,ODC1,SMOX,LPCAT3,SLC44A5
GO:0033137	negative regulation of peptidyl serine phosphorylation	GO_NEGATIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION	0.288121994010562	0.906830915034215	0.594559179078309	0.874021847099279	21	INPP5J,DMD,SMAD7,CNKSR3,DDIT4,PAQR3,BAK1,GPD1L,DKK1,OGT
GO:0001936	regulation of endothelial cell proliferation	GO_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	0.215976542008616	0.933361123600498	0.594585660351097	0.874021847099279	89	PTPRM,NRP1,PDGFB,ATPIF1,VIP,PPP1R16B,ATOH8,ITGB3,ATP5A1,CCL24,VEGFB,GJA1,CXCR3,DLL4,CDH13,MTOR,PDCD6,SEMA5A,TEK,VEGFA,CYBA,ENG
GO:0097502	mannosylation	GO_MANNOSYLATION	-0.259053319871789	-0.91284142485321	0.594625677319474	0.874021847099279	29	PIGV,DPY19L1,ALG3,DPY19L3,FKTN,PIGZ,ISPD,ALG1L,ALG2,ALG1,ALG12
GO:0031577	spindle checkpoint	GO_SPINDLE_CHECKPOINT	0.288029077140329	0.90653846984708	0.595242050089511	0.87454593653483	21	CSNK2A1,MAD2L1,APC,KLHL22,TPR,MAD1L1,PLK1,ATM
GO:0042276	error prone translesion synthesis	GO_ERROR_PRONE_TRANSLESION_SYNTHESIS	-0.290385854857559	-0.901779875607918	0.596207606457904	0.875582374929017	18	RPA3,UBA52,RPA2,UBB,PCNA,POLE2,RFC1,RPS27A,RFC4,RFC2
GO:0002714	positive regulation of b cell mediated immunity	GO_POSITIVE_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY	0.278372631833115	0.907085007108007	0.596919457412785	0.876226421739398	24	UNG,XCL1,CD40,IL4,TNF,EXOSC3,IL2,TNFSF4,PAXIP1
GO:0044282	small molecule catabolic process	GO_SMALL_MOLECULE_CATABOLIC_PROCESS	0.186370835801757	0.954523920754971	0.597380846040962	0.876226421739398	299	SLC25A17,LRP5,DECR1,IVD,BAD,PPARD,LPIN1,ACOX3,HIBCH,DMGDH,ACAD9,MCCC2,ACADM,DDO,AMT,MMAA,PGM5,AUH,ALDH7A1,ACAD10,PPAT,CRYL1,OTC,HAGH,DLD,PGAM2,PGAM1,RENBP,FUT5,THNSL2,ADH5,OGDH,CEL,HAAO,IMPA2,ASRGL1,PTEN,CYP27B1,INPP1,PFKM,SARDH,GCK,PLA2G15,IDO1,SMPD4,HADH,ACAT1,PFKFB4,ECI2,GLUD1,GOT2,ETFA,PFKP,ALDOC,PEX7,PARK7,ADH7,ACOT8,FUT4,HADHB,ALDOA,HK3,NAGK,PCCB,PRODH2,ECHS1,ENO2,GALK1,GOT1,BCKDK,HOGA1,GCDH,ACADVL,PCCA,DBT,GLUD2,HADHA,NUDT15,DLST,CYP1A1,NPL,SCP2,MTMR2,PIPOX,GPI,MCEE,ACMSD,CTH,MT3,MUT,ACADSB,SMPD1,ADH4,QDPR,AKR1D1,CRYM,SYNJ1,CRABP1,ALDH1A1,PGK1,GALT,ARG1,NOS2
GO:0010447	response to acidic ph	GO_RESPONSE_TO_ACIDIC_PH	-0.298882426715496	-0.89806648208369	0.59767950299803	0.876226421739398	16	PKD1L3,PCK1,SST,SERPINF1,GIP,NOX1
GO:0019218	regulation of steroid metabolic process	GO_REGULATION_OF_STEROID_METABOLIC_PROCESS	-0.216503963030562	-0.929266052816975	0.597874797874798	0.876226421739398	70	APOA2,APOC1,ACADL,BMP2,TSPO,AGTR1,AKR1C3,DGAT2,STAR,SCAP,BMP5,LEP
GO:0034694	response to prostaglandin	GO_RESPONSE_TO_PROSTAGLANDIN	-0.251239878686649	-0.914298497839039	0.598222596516112	0.876226421739398	33	CCL19,P2RY4,CCL21,AKR1C3,PPARG,PTGER2,YY2,EDN1,PTGER4,PTGFR,ACACA
GO:0045454	cell redox homeostasis	GO_CELL_REDOX_HOMEOSTASIS	-0.225600049259211	-0.924939697274995	0.598333029695755	0.876226421739398	56	PDIA4,NME9,PDIA6,TXNDC2,GRXCR1,TXNDC12,AIFM3,NCF4,ERP44,PDIA5
GO:0031929	tor signaling	GO_TOR_SIGNALING	0.312636892009511	0.898351940935865	0.598468373018086	0.876226421739398	15	FLCN,PINK1,FNIP1,MTOR,CCDC88A,LARP1,RPTOR,RPS6KB1
GO:0010042	response to manganese ion	GO_RESPONSE_TO_MANGANESE_ION	-0.298658073269169	-0.897392356433343	0.598740177933632	0.876243234315046	16	ATP13A2,TSPO,EIF2AK3,ADAM9
GO:0060008	sertoli cell differentiation	GO_SERTOLI_CELL_DIFFERENTIATION	-0.289677487622994	-0.899580073840767	0.599631596055911	0.877166428650237	18	RARA,DMRT1,SDC1,RAB13
GO:0070646	protein modification by small protein removal	GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL	0.209064001697306	0.933926971125908	0.600147515394775	0.87753976403945	108	USP46,VCPIP1,ATXN3L,USP30,ZRANB1,STAMBP,BAP1,USP13,USP2,USP24,SENP5,COPS6,KAT2A,COPS7A,USP38,USP48,COPS7B,YOD1,ATXN7,USP36,USP28,ENY2,USP14,OTUD7A,USP5,USP18,SHMT2,BABAM1,USP34,USP10,USP31,USP44,ATXN3,USP22,SUPT3H,USP20,USP19,OTUD3,USP12,TNFAIP3,COPS5,UCHL5
GO:0016572	histone phosphorylation	GO_HISTONE_PHOSPHORYLATION	0.280301014722854	0.903760171888344	0.600510635171375	0.877689447671232	23	GSG2,JAK2,PRKAA2,CDK1,PKN1
GO:0042461	photoreceptor cell development	GO_PHOTORECEPTOR_CELL_DEVELOPMENT	-0.243044115263719	-0.914201904143753	0.601285381583662	0.877918899461374	38	CNGB1,PRKCI,PDE6C,GNAT1,TULP1,RDH13,NRL,IFT20,RP1L1,GNGT1,PRDM1,IFT140
GO:1902236	negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway	GO_NEGATIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	-0.297918181814545	-0.895169168797055	0.602376777712838	0.877918899461374	16	CREB3L1,TXNDC12,XBP1,MAGEA3
GO:0019228	neuronal action potential	GO_NEURONAL_ACTION_POTENTIAL	-0.261442932233998	-0.905139620103425	0.602788607678583	0.877918899461374	27	SCN4A,P2RX1,KCNMB2
GO:0006891	intra golgi vesicle mediated transport	GO_INTRA_GOLGI_VESICLE_MEDIATED_TRANSPORT	0.250022708156589	0.911224158876314	0.602880063599899	0.877918899461374	38	RAB6A,COG5,GOLGA4,COPZ1,RAB6B,VTI1A,COPA,RAB41,COG2,GOSR1
NA	membrane budding	GO_MEMBRANE_BUDDING	0.210021751442071	0.932209671309031	0.602949283351709	0.877918899461374	104	LRSAM1,SEC24C,VPS4A,TRAPPC9,GOLGA2,F8,ARF1,RAB1B,CHMP7,GRIA1,VPS37B,GORASP1,TGFA,WASL,FNBP1L,MITD1,PPP6R1,P2RX7,TRAPPC5,VPS37C,GBF1,CHMP6,VAPB,TRAPPC2,CD59,TSG101,SEC23IP,VPS37A,SEC16A,SEC24B,GOLPH3,CHMP1B,FCHO1,CHMP4B,ATP8A1,PIK3C2A,CHMP4C,NAPA,EPS15,SERPINA1,BET1,TRAPPC4
GO:1902656	calcium ion import into cytosol	GO_CALCIUM_ION_IMPORT_INTO_CYTOSOL	-0.239994773870551	-0.913894425488204	0.603583426651736	0.877918899461374	40	BBC3,CCL3,CCL19,RYR1,CCL21,RYR3,ITPR3,F2R,RASA3,PKD2,TRPA1,FGF2,HTR2A
GO:0045671	negative regulation of osteoclast differentiation	GO_NEGATIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION	-0.271943377619527	-0.901988222357731	0.603687445127305	0.877918899461374	23	CCL3,CTNNB1,TJP2,ZNF675,CLDN18,CARTPT,MAFB,GPR55,TLR3,LTF,CALCA
GO:0061013	regulation of mrna catabolic process	GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS	0.276988983866031	0.902576351505648	0.603977502481344	0.877918899461374	24	CPEB3,TNRC6C,TNRC6B,CNOT8,CNOT1,DHX34,POLR2G,ZFP36L2,RC3H1,UPF1,PNPT1,NANOS3,NBAS
GO:0033673	negative regulation of kinase activity	GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY	-0.182867993412154	-0.952965350894011	0.604169377716472	0.877918899461374	239	CDKN2B,GPRC5A,DUSP18,SFN,MAPK8IP1,TARBP2,FLRT3,BMP4,SFRP2,HEXIM1,PTPN2,RGS4,LRRC4B,ITGB1BP1,CDKN2C,SOCS1,FLRT2,MEN1,LRRC19,TP73,ERRFI1,PYCARD,CEBPA,CDKN1A,FLRT1,MSTN,ADIPOQ,FABP4,PODNL1,IRAK3,PRKAR2B,CASP3,PPP2R5A,SORL1,MYCNOS,PPM1E,PRKAR1B,INPP5K,ZNF675,DEPTOR,MVP,DCN,CORO1C
GO:0045747	positive regulation of notch signaling pathway	GO_POSITIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY	-0.251932630459367	-0.909790259639292	0.604533055376904	0.877918899461374	32	POGLUT1,ITGB1BP1,STAT3,TSPAN15,NOV,TSPAN5
GO:0046500	s adenosylmethionine metabolic process	GO_S_ADENOSYLMETHIONINE_METABOLIC_PROCESS	-0.297371027057425	-0.893525106436874	0.604584713293071	0.877918899461374	16	OCLN,PEMT
GO:0036152	phosphatidylethanolamine acyl chain remodeling	GO_PHOSPHATIDYLETHANOLAMINE_ACYL_CHAIN_REMODELING	-0.274462826227492	-0.899812975742053	0.604692390186251	0.877918899461374	22	PLA2G2A,PLA2G16,PLA2G2D,PLA2G4F,LPCAT3,PLA2G2F,PLA2G4A
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	0.237591490536903	0.915098679981782	0.6048	0.877918899461374	49	AGT,RBCK1,CTNNA1,PTEN,AGTR2,BCL2L14,TNFSF10,G0S2,DAPK3,MAL,TIMP3,FAF1,HYAL2,BID
GO:0051985	negative regulation of chromosome segregation	GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION	0.274106866047902	0.902442778381282	0.604998990659008	0.877918899461374	25	CSNK2A1,MAD2L1,APC,ATRX,KLHL22,TPR,MAD1L1,ESPL1,PLK1,ATM,TNKS
GO:0043586	tongue development	GO_TONGUE_DEVELOPMENT	-0.281083177360552	-0.898218889390966	0.605347896088073	0.877918899461374	20	CYP26B1,BMP4,WNT10B,CTNNB1
NA	regulation of nf kappab import into nucleus	GO_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS	-0.233833964185078	-0.914714017330916	0.605390556393686	0.877918899461374	45	CCL19,IL18,TNFSF14,EDAR,NOV,PSMD10,NLRP3,NLRP12,TLR9,RHOA,TLR2
GO:0010039	response to iron ion	GO_RESPONSE_TO_IRON_ION	0.255773106291552	0.908004071394141	0.605646100116414	0.877918899461374	34	ATP7A,CCND1,DRD2,GSK3B,ALAD,HAMP,TFF1,FXN,ABCG2,CYP1A1,LCT
GO:1902115	regulation of organelle assembly	GO_REGULATION_OF_ORGANELLE_ASSEMBLY	0.202593061753631	0.936113476050882	0.6056469075653	0.877918899461374	134	LRSAM1,NPM1,LRRK2,BMP10,PINK1,VPS11,RAB1B,CAV3,RAB3GAP1,VDAC3,PIP4K2C,TBC1D13,PAN2,AKAP13,PIKFYVE,CNOT6L,PIP4K2B,EP300,MAP4,TNF,CSF2,PLK4,TBC1D10B,TBC1D8,TBC1D21,MYLK3,RDX,HTT,TPR,ATXN2L,PROX1,TBC1D30,CNOT1,NOTO,CAPG,TSG101,AMBRA1,MEF2C
GO:0071380	cellular response to prostaglandin e stimulus	GO_CELLULAR_RESPONSE_TO_PROSTAGLANDIN_E_STIMULUS	0.30128611961163	0.895034190289818	0.605862222883499	0.877918899461374	17	GNAS,GNG2,PRKAA2,PRKCE,TNFSF4
GO:0045947	negative regulation of translational initiation	GO_NEGATIVE_REGULATION_OF_TRANSLATIONAL_INITIATION	0.306041033099536	0.89423201349588	0.6061332589908	0.877918899461374	16	EIF2B5,PAIP2B,PAIP2,EIF2B4,TPR,EIF2AK1,EIF2S1
GO:0001562	response to protozoan	GO_RESPONSE_TO_PROTOZOAN	0.293305415938759	0.897548979901154	0.60614483729894	0.877918899461374	19	BATF2,SPN,CD40,IL4,TSPAN32,IRF8
GO:0006525	arginine metabolic process	GO_ARGININE_METABOLIC_PROCESS	-0.291828696523545	-0.892500936267181	0.608253666133149	0.880293691424121	17	ASS1,CPS1,DDAH2,OAT,FAH
GO:0007159	leukocyte cell cell adhesion	GO_LEUKOCYTE_CELL_CELL_ADHESION	-0.182624008324936	-0.951693890919438	0.608307524139187	0.880293691424121	239	DPP4,EZR,CCL19,CD7,CYP26B1,PTPN2,TNFSF14,ELF4,GATA3,CEBPB,GCNT1,CERCAM,ANXA1,UMOD,PODXL2,PLA2G2D,FUT7,RAG2,CTNNB1,CCL21,RIPK2,IFNA14,IRF4,RIPK3,LEP,S100A9,IFNE,RPL22,NKX2-3,RAG1,ZBTB1,EIF2AK4,LAT,FAS,APBB1IP,CLEC4E,IFNA16,IFNAR1,BAX,MSN,NKAP
GO:0034723	dna replication dependent nucleosome organization	GO_DNA_REPLICATION_DEPENDENT_NUCLEOSOME_ORGANIZATION	0.276011353522522	0.89939071568631	0.609215895305665	0.8803247870913	24	NASP,HIST1H3G,HIST1H3B,HIST1H4F,HIST1H3E,ASF1B,ASF1A,HIST1H4A
GO:0050691	regulation of defense response to virus by host	GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_HOST	-0.197611817966577	-0.93806687225484	0.609363587671033	0.8803247870913	125	SNRPB2,TARBP2,CPA3,TRAF3IP2,ALPK1,LENG9,FGF7,ANXA5,MB21D1,TMEM39A,APOBEC3F,HCAR1,FGFBP1,UBA52,MSTN,PHYHIP,ZCCHC17,HPR,SLC25A19,LMCD1,EIF2AK4,YIPF1,HIST1H3C,FABP1
GO:0033273	response to vitamin	GO_RESPONSE_TO_VITAMIN	-0.206307703853059	-0.930706399243881	0.610031407183508	0.8803247870913	92	SLC34A1,RARA,BCHE,AQP3,ALPL,PEMT,TSPO,ZNF354A,F7,CAT,PIM1,TYMS,LEP,HLCS,PPARG,SPARC,HMBS
GO:0007263	nitric oxide mediated signal transduction	GO_NITRIC_OXIDE_MEDIATED_SIGNAL_TRANSDUCTION	0.292437663769967	0.894893556470209	0.610462530575939	0.8803247870913	19	AGT,GUCY1B3,GUCY1A3,AGTR2,CD36,NDNF,NOS2,DDAH1,PDX1
GO:0010948	negative regulation of cell cycle process	GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS	0.193253531684362	0.942709777462596	0.610520582312746	0.8803247870913	199	PPP2R5C,FOXN3,AURKAIP1,FBXW7,NPM1,CSNK2A1,VPS4A,CCND1,TAOK3,MAD2L1,PLAGL1,KANK2,OSM,ZNF655,PTEN,CDK5RAP3,PRKAR1A,DDX39B,TFDP2,CNOT6L,E2F8,SMC1A,EZH2,CNOT4,DGKZ,EP300,FBXO31,NME6,MYO16,CDKN1B,CDK1,APC,PRPF19,HUS1,GADD45A,CDC25C,CNOT8,ARID3A,ATRX,CLSPN,GIGYF2,KLHL22,FOXO4,TPR,PRKDC,MAD1L1,MRE11A,TOM1L2,CTDSP2,ESPL1,RASSF1,CNOT1
GO:0045428	regulation of nitric oxide biosynthetic process	GO_REGULATION_OF_NITRIC_OXIDE_BIOSYNTHETIC_PROCESS	-0.230371589909774	-0.914510250651755	0.610605514507118	0.8803247870913	48	ASS1,PTGIS,TSPO,OPRM1,KLF4,EGFR,AGXT2,CD34,DDAH2,HSP90AA1,PKD2,EDN1
GO:1903205	regulation of hydrogen peroxide induced cell death	GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH	0.30000881060025	0.89123967350881	0.610902395476864	0.8803247870913	17	TRAP1,LRRK2,PINK1,PARK7,HDAC6,ENDOG,HSPH1
GO:0001659	temperature homeostasis	GO_TEMPERATURE_HOMEOSTASIS	-0.265471691576317	-0.900513104908075	0.611017116741008	0.8803247870913	25	MC3R,ACADL,CIDEA,STAT3
GO:0033005	positive regulation of mast cell activation	GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION	-0.30108139913118	-0.886975935379611	0.611280652771465	0.8803247870913	15	NR4A3,VAMP8,FCER1A,IL4R,ZAP70,VAMP7,CD226,SNX4
GO:0035115	embryonic forelimb morphogenesis	GO_EMBRYONIC_FORELIMB_MORPHOGENESIS	-0.256391474220684	-0.903461722720471	0.611522724759482	0.8803247870913	29	OSR1,RDH10,WNT9A,CTNNB1,MSX2,RSPO2
GO:0007178	transmembrane receptor protein serine threonine kinase signaling pathway	GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	-0.188543458539592	-0.944486776080481	0.611529074302393	0.8803247870913	178	CGN,GDF5,AMHR2,ZCCHC12,TGFBR1,BMP4,BMP2,FMOD,T,SKIL,GDF10,ACVR1,IRAK1,FUT8,BMPR1B,TOB1,ACVR1C,MSX2,LEFTY1,UBA52,MSTN,BMP5,SMAD2,HPGD,SMURF2,LTBP2,MAGI2,ETV2,ADAM9,ACVR2B,F11R,ACVR1B,RHOA,NODAL,AFP,FSHB,AKAP4,HNF4A,UBB,USP9Y,INHBA
GO:0007602	phototransduction	GO_PHOTOTRANSDUCTION	-0.238780940090805	-0.909272175149631	0.611802911534155	0.8803247870913	40	CNGB1,PDE6C,GNAT1,OPN1LW,AIPL1,OPN3,RS1,PITPNM1,GUCA1A,GNGT1,CDS1,PDE6G,PDE6A,RCVRN,OPN1SW,GRK1,NR2E3
GO:2000249	regulation of actin cytoskeleton reorganization	GO_REGULATION_OF_ACTIN_CYTOSKELETON_REORGANIZATION	-0.252180210865905	-0.903292225043585	0.611952861952862	0.8803247870913	31	BAIAP2L2,BAIAP2,RHOD,CDK5,RAPGEF3,SEMA3E,F11R,ABL1,HRAS,PTK2B,FES
GO:0010803	regulation of tumor necrosis factor mediated signaling pathway	GO_REGULATION_OF_TUMOR_NECROSIS_FACTOR_MEDIATED_SIGNALING_PATHWAY	-0.236310406682496	-0.910526091802651	0.611990493699834	0.8803247870913	42	PTPN2,PYCARD,RIPK1,PELI3,CHUK,TRADD,UBA52,TNFRSF1A,ADIPOQ,IKBKG,ZNF675
GO:0071594	thymocyte aggregation	GO_THYMOCYTE_AGGREGATION	-0.234113837195627	-0.911357647427312	0.612473862895429	0.880643751604449	44	GATA3,RAG2,CTNNB1,RIPK3,RAG1,ZBTB1,FAS,NKAP,MAFB,RPS6,BCL2,ZAP70,AIRE
GO:0001505	regulation of neurotransmitter levels	GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS	0.195969629067241	0.938824795146849	0.613165028522011	0.880824552004965	173	C2CD4A,BRSK1,SLC6A2,CHAT,SLC5A7,GPM6B,CPLX1,SYT9,NRXN1,DRD4,SYT8,LRRK2,CAMK2A,CPLX3,ATP1A2,DRD2,SYTL2,VAMP2,STX1A,SYT7,SNCG,RAB3GAP1,CLN8,PRIMA1,PPP1R9A,CADPS,PPFIA4,GRIK5,STX4,PARK7,SYT12,PPFIA1,SYTL3,CACNA1B,P2RX7,BAIAP3,RPH3AL,SLC30A1,PIP5K1C,GRM4,C2CD4B,ATP2A2,NAALAD2,PFN2,RAB3A,TH,RIMS3,DOC2B,MEF2C
GO:0030595	leukocyte chemotaxis	GO_LEUKOCYTE_CHEMOTAXIS	-0.201908478890692	-0.932215997247493	0.613241333205997	0.880824552004965	105	IL16,SCG2,CCL3,TNFSF11,CCL19,ARHGEF5,CCR6,ANO6,RPS19,ANXA1,S100A12,CCL21,SAA1,IL17RC,C5AR1,S100A9,EDNRB
GO:0002698	negative regulation of immune effector process	GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	-0.205960088111612	-0.929138216432475	0.613384655347486	0.880824552004965	92	CD55,APOA2,TARBP2,TRAF3IP1,C4BPA,HTRA1,ANGPT1,FOXF1,SERPING1,RPS19,ANXA1,C4BPB,IRAK3,MASP1,TRIM38
GO:0061099	negative regulation of protein tyrosine kinase activity	GO_NEGATIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY	-0.283124350792352	-0.891715442317371	0.61407967331335	0.88096230475822	19	GPRC5A,PTPN2,ERRFI1,MVP
NA	regulation of transcription factor import into nucleus	GO_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS	0.213184222806328	0.924743318980941	0.614110333570647	0.88096230475822	91	PIK3R1,RBCK1,PYDC2,AKAP1,C8orf4,SUFU,GSK3B,AKAP6,DDX58,CSF3,MBTPS1,AGTR2,PPP3R1,MTOR,IL18R1,TNF,TMEM173,FAF1,MDFI,CD36,SMAD3,LITAF,NFKBIA,TLR4,EDA,PRKCQ
GO:0090199	regulation of release of cytochrome c from mitochondria	GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA	0.243897367480357	0.908512399916412	0.61427797833935	0.88096230475822	42	PARL,BAD,MOAP1,PPIF,PINK1,APOPT1,TNFSF10,FAM162A,FXN,BID,OPA1,BAK1,HRK,BMF,BNIP3
GO:0007017	microtubule based process	GO_MICROTUBULE_BASED_PROCESS	-0.171992157107231	-0.963023109984995	0.614868188789536	0.88096230475822	465	KIF2C,KIF18A,CAPN6,HAP1,EZR,KIF5A,TRAF3IP1,MAP7D3,C11orf63,IFT57,CUL7,DNAH3,KATNB1,DNAH2,DNAH6,SS18,STMN3,AP3M1,WDR35,KIF20A,KLC3,CEP135,CNTLN,SGK1,CAMSAP3,KATNA1,NEK2,SSX2IP,GAS2L1,KIF3A,ACTR3,CETN2,TUBB8,CCDC114,TUBA3C,DNAL4,CTNNB1,CCP110,FIGNL1,DNAH17,MARK4,TTLL1,HDAC3,WDR19,HIF1A,DNAH1,TTC30B,KIF6,KIF7,SPICE1,WDR43,CCNB1,KIAA0101,USP33,KIAA0196,TUBA3D,RPS3,MAP6D1,ADCY10,SPEF2,FBXO5,CEP152,HDGFRP3,AP3S1,FGF13,GCC2,SLC16A1,FMN2,CHEK2,PCM1,TTC26,XRCC2,KIF4A,DYNLL1,MAP3K11,IFT20,AURKB,CHD3,E2F4,DOCK7,KIF3C,KIF21A,TPX2,MID1,CCDC13,CLN3,AURKC,PKD2,RHOA,MAP7D2,ZW10,RP1L1,TUBA1A,SRGAP2,STIL,CDC42,DYNC1I1,LLGL1,ROPN1L,SNAPIN,UBB,MOS,DLG1,DNAH5,AXIN1,TTL,CEP57,SPAST,LRRC6,STMN1,SUN2,DYNC2H1,SMC3,TUBAL3,RAB11A
NA	mrna 3 end processing	GO_MRNA_3_END_PROCESSING	0.222694936471945	0.917337997730853	0.614956595235161	0.88096230475822	68	PAF1,NCBP1,APP,WDR33,TUT1,CLP1,DDX39B,SRSF4,CPSF1,SYMPK,NCBP2,RNPS1,SRSF1,PAPOLG,DHX38,RBM8A,CPSF6,CHTOP
GO:0032148	activation of protein kinase b activity	GO_ACTIVATION_OF_PROTEIN_KINASE_B_ACTIVITY	0.291382560592096	0.891664816973678	0.615132310429175	0.88096230475822	19	PDGFB,ADRA2C,PINK1,PRKCZ,PARK7,CCDC88A,NTRK3,MT3,ADRA2B,INSR
GO:0008210	estrogen metabolic process	GO_ESTROGEN_METABOLIC_PROCESS	-0.279062154313144	-0.89176058372457	0.615312649580088	0.88096230475822	20	SGPL1,STAR,RDH8,HSD17B14,AKR1B15,HSD17B12,CYP1B1,SULT1E1,HSD3B1,HSD17B11,HSD17B4
GO:0042157	lipoprotein metabolic process	GO_LIPOPROTEIN_METABOLIC_PROCESS	-0.19834001521879	-0.933478659931442	0.61585395380369	0.881001432501086	118	APOA2,APOC1,NMT2,ZDHHC20,PIGV,PIGW,AMN,SDC1,NPC1L1,PIGX,APOL6,ALOX12B,LPL,PLAUR,PIGU,GOLGA7,MAP6D1,ABCA1,ZDHHC8,PRKACG,APOM,PIGZ,ABCG1,LRP1,ZDHHC3,PIGF,PIGQ,PORCN,ZDHHC23,PIGK,OLR1,LYPLA2
GO:0006308	dna catabolic process	GO_DNA_CATABOLIC_PROCESS	-0.261852660603864	-0.897504917595287	0.615863449398412	0.881001432501086	26	DNASE1L2,DNASE1,XRN2,CASP3,HMGB2,DNASE2,FOXL2,DFFB,KPNA1,TATDN1
GO:0000387	spliceosomal snrnp assembly	GO_SPLICEOSOMAL_SNRNP_ASSEMBLY	0.250935522221726	0.902561621696356	0.616761904761905	0.881882910063868	36	PRMT7,PRPF6,PRPF3,LSM4,SMN1,PRPF31,SNRPC,PRPF19,CD2BP2,DDX20,WDR77,PRPF8,RBM22,SART3,SRSF12,GEMIN2,STRAP,CLNS1A
GO:0032642	regulation of chemokine production	GO_REGULATION_OF_CHEMOKINE_PRODUCTION	-0.220018002092226	-0.918446328524084	0.617017370751968	0.881882910063868	61	FFAR3,WNT5A,KLF4,PYCARD,RIPK2,LPL,HIF1A,ADIPOQ,C5,TLR9,ADCYAP1,TLR2,MIF,ELANE,IL4R,IL10,MAP2K5,TLR3,SNAI2
GO:0006338	chromatin remodeling	GO_CHROMATIN_REMODELING	0.201295713596771	0.931258024356452	0.617598322681005	0.881882910063868	135	SMARCB1,HILS1,NASP,CENPK,NPM1,HDAC2,CENPA,ESR1,RERE,HMGA1,HELLS,HDAC4,PBRM1,SMARCD3,CHD8,HIST1H4F,SMYD1,PSME4,KAT2A,HIST1H2BA,CENPN,SOX9,MSL3P1,ATRX,BPTF,CECR2,CENPI,BAZ2A,ACTL6B,ANP32E,CBX3,SATB1,GATAD2B,HDAC5,SCMH1
GO:0043507	positive regulation of jun kinase activity	GO_POSITIVE_REGULATION_OF_JUN_KINASE_ACTIVITY	0.227856303251923	0.911869843835914	0.61777682892115	0.881882910063868	59	DVL2,TIAM1,ZAK,TAOK3,SASH1,ZEB2,MAP3K4,FZD10,DBNL,DUSP19,TNF,PKN1,EPHA4,MAPK8IP3,MDFI,GAB1,MAP4K2
GO:0051592	response to calcium ion	GO_RESPONSE_TO_CALCIUM_ION	0.207972192338063	0.92593285062031	0.618137727022565	0.881882910063868	106	RASGRP2,TSHB,BAD,TPH2,KCNMB3,SCN5A,CALM3,CCND1,RYR2,CAPN3,SLC6A1,PPIF,GIPR,TTN,CALM1,EP300,PDCD6,KCNMA1,HOMER1,P2RX7,TNNT2,KCNIP2,CRHBP,KCNMB1,ENDOG,APOBEC1,ITPKB
GO:0022407	regulation of cell cell adhesion	GO_REGULATION_OF_CELL_CELL_ADHESION	-0.175380906239779	-0.957080904099117	0.618258753249627	0.881882910063868	358	ASS1,PRKCA,CD55,DPP4,CCL28,TNFSF11,CCL19,EFNB3,RARA,IL18,CYP26B1,SPINT2,BMP4,WNT5A,BMP2,TNFRSF21,PTPN2,TNFSF14,GATA3,CEBPB,ALOX15,EFNA5,HLA-DRB5,FOXA1,C1QTNF1,IL27,ANXA1,KLF4,MAP3K8,XBP1,PLA2G2D,CTNNB1,IL6ST,PYCARD,CCL21,NR4A3,RIPK2,IL36B,PIEZO1,IRF4,RIPK3,ADAMTS18,ADIPOQ,CASP3,LEP,TNFSF9,LILRB2,RAG1,ZBTB1,PAK3,LAT,CDH1,PRELID1,NLRP3,SART1,BTLA,GRAP2,PDPK1,NKAP,ZNF703,ABAT,IL2RA,NODAL,MUC21,LMO1,VTCN1,CDC42,HLA-DRB1,GPAM,DLG1,PLA2G2F,ABL1,PAWR,IL20RB,CD276,PODXL,SWAP70,IL4R,CD46
GO:0043405	regulation of map kinase activity	GO_REGULATION_OF_MAP_KINASE_ACTIVITY	0.184957073394714	0.947915494118188	0.618338995486227	0.881882910063868	301	MADD,RAPGEF1,TAOK2,PDE5A,MAPKAPK2,PDGFB,TRIB2,TNIK,RGS3,LPAR3,DRD4,DVL2,TIAM1,FLT1,ZAK,DIRAS2,LRRK2,MAP3K15,TAOK3,SASH1,CRKL,ZEB2,ADRA2C,MAPKAPK3,HMGCR,PLCE1,FGF1,GSK3B,JAK2,CAV3,CDK5RAP3,GH1,MAP3K4,CD300A,DIRAS1,FZD10,CD40,CDK12,EZH2,LAX1,MAPKAPK5,TGFA,RAF1,FGFR1,DBNL,DUSP19,DUSP21,TNF,PIK3R5,RGS14,MAPK1,CDK1,VEGFA,PKN1,P2RX7,SOD1,TRIB3,GADD45A,DUSP3,EPHA4,MAPK8IP3,MAGED1,ADORA2B,PLCG1,MDFI,HYAL2,GRM4,GAB1,DUSP7,MAP4K2
GO:0043409	negative regulation of mapk cascade	GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE	-0.194479339523988	-0.935227598931232	0.618575624082232	0.881882910063868	135	DUSP18,EZR,MAPK8IP1,FOXM1,BMP4,SFRP2,PTPN2,RGS4,ITGB1BP1,ATF3,KLF4,MEN1,TP73,NLRP6,ERRFI1,HDAC3,ADIPOQ,IRAK3,SORL1,FKTN,LMO3,PSMD10,INPP5K,ZNF675,NLRP12
GO:0050795	regulation of behavior	GO_REGULATION_OF_BEHAVIOR	0.227184834941684	0.912031702053886	0.619113622632121	0.882041959960742	60	OPRL1,NRXN1,DLG4,DRD2,ZFHX3,TACR3,GJA1,UCN,NPS,PTGDS,ADA,ESR2,MTOR
GO:0043406	positive regulation of map kinase activity	GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY	0.19298600181359	0.938831432033912	0.619465661475383	0.882041959960742	195	MADD,PDE5A,MAPKAPK2,PDGFB,LPAR3,DRD4,DVL2,TIAM1,FLT1,ZAK,DIRAS2,LRRK2,TAOK3,SASH1,ZEB2,ADRA2C,MAPKAPK3,PLCE1,FGF1,GH1,MAP3K4,DIRAS1,FZD10,CD40,EZH2,MAPKAPK5,TGFA,FGFR1,DBNL,DUSP19,TNF,PIK3R5,MAPK1,CDK1,VEGFA,PKN1,P2RX7,SOD1,EPHA4,MAPK8IP3,MAGED1,ADORA2B,MDFI,GRM4,GAB1,DUSP7,MAP4K2,PDE6H,EGF,NTRK3,TLR4,TGFB3
GO:1901655	cellular response to ketone	GO_CELLULAR_RESPONSE_TO_KETONE	-0.214317443982505	-0.919881199547982	0.61947331947332	0.882041959960742	70	ASS1,AQP1,NDOR1,KLF4,GNAI1,P2RY4,ERRFI1,STAR,MSTN,PPARG,PTGER2,HMBS,ADCY2,KLF6,MSN,PTGER4,ATP2B1,SERPINF1,ACACA,NTS
GO:0006261	dna dependent dna replication	GO_DNA_DEPENDENT_DNA_REPLICATION	0.21356990185288	0.921290222892439	0.621175978966796	0.884087180920801	88	RPA4,ORC2,MCM4,MCM7,HMGA1,POLA2,FBXO18,ZRANB3,DNAJA3,LIG3,REV3L,POLG,POLD2,GINS3,CCNE2,MMS22L,RFC3
GO:0051289	protein homotetramerization	GO_PROTEIN_HOMOTETRAMERIZATION	0.229383653212161	0.90854308281976	0.622232126938848	0.884087180920801	56	TK1,DECR1,ATPIF1,PPAT,KCNJ2,GOLGA2,RXRG,GBP5,SOD2,RXRA,ALDOA,CRTC2,ACACB,SHMT2,CTH,ACTN2,CRTC3,VASP,DCTPP1,MIP,DCXR
GO:0044070	regulation of anion transport	GO_REGULATION_OF_ANION_TRANSPORT	0.201447039406863	0.928648103866897	0.622235393734124	0.884087180920801	132	SLC17A3,GPM6B,AKT2,DRD4,P2RY2,CLCN6,ATP1A2,DRD2,OPRK1,CLCN4,VAMP2,SLC6A1,PINK1,SNCG,VDAC2,RAB3GAP1,VDAC3,AGTR2,ANO1,MTOR,GABBR1,NPY5R,NCOR1,GRK6,CA2,VDAC1,P2RX7,SLC38A3,ABCB4,MAOB,PTAFR,BSND
GO:0051898	negative regulation of protein kinase b signaling	GO_NEGATIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING	-0.249057554960872	-0.899407659816916	0.622740679958307	0.884087180920801	32	PHLDA3,KLF4,MSTN,MAGI2,MTM1,INPP5K,EPHA2,PHLPP1,SFRP5,DLG1,LMBRD1,SIRT1,BANK1
GO:0140014	mitotic nuclear division	GO_MITOTIC_NUCLEAR_DIVISION	0.183494885269145	0.948099885327362	0.622806739722557	0.884087180920801	325	FBXL7,GSG2,NDE1,SPAG5,TUBGCP5,NSUN2,CDC26,POGZ,BIRC8,VCPIP1,CLASP1,BIRC6,KLHL21,PAFAH1B1,AKAP8,NEK1,VPS4A,NCAPH,CLIP1,TUBGCP2,ARHGEF2,MAD2L1,GOLGA2,HELLS,FZR1,CETN1,PBRM1,PTEN,CHMP7,ANAPC1,TTN,GORASP1,SMC1A,PPP5C,LATS1,FAM83D,SMC2,WASL,MAU2,KIFC1,ANAPC11,NEK9,INCENP,MAPRE2,RECQL5,RGS14,CENPN,CDK1,PPP1R12A,NAA50,DCTN1,NCAPD3,CDC25C,DLGAP5,SETDB2,PBK,TUBGCP6,KIF25,CCNA1,CLTCL1,CEP57L1,CSNK1A1,CHMP6,KLHL22,TPR,HAUS8,ZWILCH,MAD1L1,TUBGCP3,CKAP5,CHFR,UBE2I,ESPL1,TIPIN,AKAP8L,BABAM1,MAPRE3,DIS3L2,MAPRE1,CHMP1B,PAPD7,CLASP2,PHF13,NSMCE2,SIRT2,KPNB1,FIGN,TTC28,WEE1,CENPV,CHMP4B,CENPT,SKA2,PLK1,DCLRE1A,USP44,CDCA3
GO:0030224	monocyte differentiation	GO_MONOCYTE_DIFFERENTIATION	-0.298546479242837	-0.879508144458072	0.62296820552778	0.884087180920801	15	BMP4,MT1G,PPARG,IFI16,PDE1B,JUN
GO:0046621	negative regulation of organ growth	GO_NEGATIVE_REGULATION_OF_ORGAN_GROWTH	-0.277678045929167	-0.887337578736769	0.623232235324834	0.884087180920801	20	RBP4,WWC1,TP73,STK3,MAPK11,KCNK2,WWC2,NOG
GO:0030835	negative regulation of actin filament depolymerization	GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION	-0.247274592217944	-0.899868243053093	0.623398785514827	0.884087180920801	33	LIMA1,SPTBN4,VILL,PLEKHH2,TWF1,TRIOBP,SCIN,CAPZA1,SPTBN2,SPTAN1,SWAP70
GO:0006778	porphyrin containing compound metabolic process	GO_PORPHYRIN_CONTAINING_COMPOUND_METABOLIC_PROCESS	0.252958530355394	0.89801222179614	0.624126891734575	0.884087180920801	34	COX15,ATPIF1,COX10,ALAD,FXN,HMOX2,EIF2AK1,CYP1A1,NFE2L1,SLC25A38,RSAD1,FECH,SLC25A39
GO:0044364	disruption of cells of other organism	GO_DISRUPTION_OF_CELLS_OF_OTHER_ORGANISM	-0.268255838306113	-0.889757304806818	0.624231782265145	0.884087180920801	23	DEFA5,C9,DEFA6,S100A12
GO:0090316	positive regulation of intracellular protein transport	GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT	-0.182714930287169	-0.945857527523839	0.624378624689312	0.884087180920801	227	GPR26,SFN,DPCR1,CCL19,IL18,TGFBR1,BMP4,SFRP2,TNFSF14,PEMT,TDRD12,ITGB1BP1,IPO5,XBP1,UBL4B,EDAR,WDR75,SULF2,WDR46,BCAP31,SH3GLB1,HDAC3,EGFR,UBE2L3,LEP,DAB2,ANXA13,CDK5,SORL1,CDKL2,RAPGEF3,CTSK,ZDHHC8,CDH1,KCNB1,PCM1,NLRP12,TLR9,HNMT,CTDSPL2,ASPH,NKAP,HSP90AA1,MFF,RHOA,TLR2,NODAL,MDM2,RNASE2,CDC42
GO:0045834	positive regulation of lipid metabolic process	GO_POSITIVE_REGULATION_OF_LIPID_METABOLIC_PROCESS	0.203834265588629	0.925576687605639	0.624736340749813	0.884087180920801	119	HSD17B13,AGT,AKT2,PDGFB,ATG14,EEF1A2,FLT1,ADRB2,PPARA,APOC3,NSMAF,LDLR,CYP17A1,GHSR,FGF1,ABHD6,SIRT4,IRS1,ERBB4,MTOR,CREB1,TNF,TEK
GO:0010906	regulation of glucose metabolic process	GO_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS	0.211236124458837	0.919808322834718	0.624898079558663	0.884087180920801	93	BAD,AKT2,PPARA,IGFBP3,GRB10,PGAM2,PGAM1,GSK3B,IRS1,GCK,KAT2A,PPP1R3B,PPP1R3F,COX11,MTOR,FOXO1,PPP1CB,SERPINA12,HMGB1,ACACB,PPP1R3E,PASK,PTH,PHKG2,GCG,EPM2AIP1,SORBS1,PDK3,IGFBP5,PPARGC1A,GPLD1,PGAM4,NCOA2,MST1,OGT,INSR,ARPP19
GO:0016049	cell growth	GO_CELL_GROWTH	0.203073957821259	0.926506585740385	0.625048930340215	0.884087180920801	123	AGT,NLGN3,NRP1,PDGFB,APP,TIAM1,NDRG4,ULK1,ITGB3,ZEB2,LAMB2,CAV3,DCLK1,POU4F3,ATP6V0E2,TGFBR2,AGTR2,LHX2,AR,PRKCZ,MTOR,SPG11,TNN,ARIH2,GDF9
GO:1900182	positive regulation of protein localization to nucleus	GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS	0.203115066576294	0.925812050164496	0.62515086096993	0.884087180920801	122	PIK3R1,RBCK1,HNRNPM,MCRS1,KAT7,C8orf4,AKAP6,JAK2,DDX58,CDK5RAP3,CSF3,UBR5,SHH,EP300,TCP1,ERBB4,PPP3R1,IL18R1,TNF,SEMA5A,TMEM173,PARK7,CDK1,CCT3,KANK1,HYAL2,SMAD3,TPR,BAMBI,EGF,TLR4,TGFB3,MED1,CCT7,CCT4,EDA,PRKCQ,JUP
GO:0007566	embryo implantation	GO_EMBRYO_IMPLANTATION	0.249497986066606	0.897391110355732	0.62528798185941	0.884087180920801	36	PPARD,IL11RA,SCGB1A1,STC2,TGFBR2,RPL29,RXRA,SOD1,PLAU
GO:0090181	regulation of cholesterol metabolic process	GO_REGULATION_OF_CHOLESTEROL_METABOLIC_PROCESS	-0.270776486807462	-0.887727491930912	0.625374800288897	0.884087180920801	22	ACADL,DGAT2,SCAP,ABCG1,APOE,SEC14L2,LDLRAP1,ARV1,NR1H4
GO:0046835	carbohydrate phosphorylation	GO_CARBOHYDRATE_PHOSPHORYLATION	0.289133056932347	0.884781071889633	0.625917278185457	0.884482602171389	19	PFKM,GCK,PFKFB4,HK3,NAGK,GNPTAB,GALK1
GO:0007567	parturition	GO_PARTURITION	0.292467777811168	0.882372837800606	0.626733757914477	0.885223927934007	18	TK1,PLA2G4C,PTAFR,CYP1A1,MAFF
GO:0060972	left right pattern formation	GO_LEFT_RIGHT_PATTERN_FORMATION	0.281524762725526	0.886066886576592	0.626967868150527	0.885223927934007	21	MEGF8,PKD1L1,IFT172,NKX2-5,SETDB2,FOXJ1,SMO,CITED2
GO:0003171	atrioventricular valve development	GO_ATRIOVENTRICULAR_VALVE_DEVELOPMENT	-0.280486777012768	-0.883408261169142	0.627503366783961	0.885250536006614	19	BMP2,CYR61,ACVR1
GO:0016075	rrna catabolic process	GO_RRNA_CATABOLIC_PROCESS	-0.287840836297416	-0.880304846479159	0.627611714322793	0.885250536006614	17	EXOSC2,EXOSC6,EXOSC5,EXOSC10,DROSHA,EXOSC8
GO:1903706	regulation of hemopoiesis	GO_REGULATION_OF_HEMOPOIESIS	-0.178559791170052	-0.950574834294658	0.627775706906651	0.885250536006614	285	PRKCA,CCL3,TNFSF11,CCL19,KDM1A,RARA,CYP26B1,BMP4,PTPN2,HOXA7,GATA3,CEBPB,FSHR,HIST1H4C,IL27,LEO1,ANXA1,GAS2L1,XBP1,CTNNB1,TJP2,RIPK2,RIPK1,CSF1,IL36B,HIF1A,IL20,IRF7,IRF4,TFE3,ADIPOQ,LEP,TNFSF9,LILRB2,HIST1H4D,SCIN,RAG1,ZBTB1,ATP11C,FAS,PGLYRP1,PRELID1,SLC9B2,ZNF675,CLDN18,NLRP3,IL5,HIST1H4E,SART1,HMGB2,NKAP,CARTPT,ACVR1B,HOXB8,IL2RA,MAFB,SENP1,FSHB,MYC,FOXO3,NFE2L2,TESC,MAPK11,RASSF2,TRIB1
GO:0002021	response to dietary excess	GO_RESPONSE_TO_DIETARY_EXCESS	0.281228846059132	0.885135522824649	0.62864736171862	0.886108467146095	21	BMP8A,ADRB1,ADRB2,NMUR2,GDF3,ADRB3,PPARGC1A,RMI1
GO:0006473	protein acetylation	GO_PROTEIN_ACETYLATION	0.205920006636213	0.921282940215747	0.629993148338472	0.887546935352502	109	TRIM16,NAA30,MEAF6,CREBBP,MCRS1,KAT7,DR1,TAF1,KAT8,NAA25,MED24,KAT6A,MDH2,KAT2A,EP300,ING3,FOXO1,BRD1,ATF2,NAA50,NCOA3,LDB1,SPI1,MSL3P1,CRTC2,BAG6,NCOA1,NAA11,PCGF2,KAT6B,SUPT7L,ING5,BRCA2,PER1,HCFC1,TADA1,USP22,SUPT3H,POR,ASL,EHHADH,NCOA2,MSL2,OGT,NAA60,ESCO1,PHF20,NAT8,MECP2,EPC1
GO:0043011	myeloid dendritic cell differentiation	GO_MYELOID_DENDRITIC_CELL_DIFFERENTIATION	0.288144056740791	0.881754615285646	0.630346156697057	0.887546935352502	19	BATF2,TGFBR2,IL4,CSF2,SPI1,LTBR,UBD,DHRS2,TRAF6,TGFB1
NA	regulation of protein import into nucleus translocation	GO_REGULATION_OF_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION	0.284430231753763	0.882901309530671	0.630458919319023	0.887546935352502	20	JAK2,UBR5,PDE2A,EP300,TMEM173,CDK1,MED1,OGG1,HSP90AB1,MAVS
GO:0007626	locomotory behavior	GO_LOCOMOTORY_BEHAVIOR	0.195122737482666	0.931764938407276	0.630740783928304	0.88757252454125	169	ATP7A,SCN1A,PREX2,DLG4,STRN,DRD4,NPY1R,PAFAH1B1,APP,ALS2,LRRK2,TSC1,ATP1A2,DRD2,OPRK1,HIPK2,VPS13A,CHD7,USP2,SNCG,PTEN,CLN8,ADCY5,IDO1,SLC4A10,GPRC5B,TMOD1,PARK7,CACNA1B,SOD1,NPC1,EPHA4,FXN,GNAO1,FGF12,SLURP1,ATP1A3,GIGYF2,PRKCE,NTF4,MTA1,HOXD10,NLGN2,TH,NEGR1,APBA2,QRFP,ESPN,GLRA1,CLN6,EN1,CNTN2,KLHL1,PPP3CB,PEX13,PUM1,ETV5,DRD3,NCOA2,CXCL12,MAPT,SLITRK6,DSCAM,FZD4,GRM5,CACNA1A,GRIN1,HTR2C,MECP2,GPR88,DBH,TNR,TAL1,NAGLU,OTOG
GO:0010927	cellular component assembly involved in morphogenesis	GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS	-0.183384641887673	-0.942847338655425	0.631170898262008	0.887700183035228	215	C5orf42,KRT8,KRT19,TRAF3IP1,IQCB1,C11orf63,IFT57,AGFG1,RFX4,WDR35,BBS7,SSX2IP,KIF3A,ACTG1,CCDC114,ATP6V0D1,TTLL1,WDR19,SNX10,RFX2,B9D2,DNAH1,TTC30B,MPP5,TPM1,SPEF2,DZIP1L,DYNC2LI1,ONECUT1,CEP89,PCM1,TTC26,IFT20,CEP41,ARL13B,E2F4,FBF1,CCDC13,TMEM231,RAB17,RP1L1,TMF1,KIAA0586,TTC8,AKAP4,FAM161A,BBS10,DNAH5,RAB23,LRRC6,UGT8,ABCC4,DYNC2H1,CLUAP1,HSPB11,RSG1,IFT140,SPACA1,SEPT2,EHD3,KIF24,MYOZ1,MYH10,TMEM237,TCTN2
GO:0010569	regulation of double strand break repair via homologous recombination	GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION	-0.291439078176466	-0.875701092753749	0.631686040219062	0.887700183035228	16	KDM1A,FIGNL1,RPA2,SIRT6,POLQ
GO:0033233	regulation of protein sumoylation	GO_REGULATION_OF_PROTEIN_SUMOYLATION	0.300140600036175	0.876991331469328	0.632078803085215	0.887700183035228	16	CAPN3,HDAC4,PARK7,PIAS3,PIAS4,CDKN2A,RNF4
GO:0045979	positive regulation of nucleoside metabolic process	GO_POSITIVE_REGULATION_OF_NUCLEOSIDE_METABOLIC_PROCESS	0.277380700606903	0.883519769632395	0.632266023457495	0.887700183035228	22	PINK1,PRKAA2,GCK,PARK7,VCP,P2RX7
GO:0090022	regulation of neutrophil chemotaxis	GO_REGULATION_OF_NEUTROPHIL_CHEMOTAXIS	0.269348572059978	0.886777034181839	0.632398010680663	0.887700183035228	25	C1QBP,XCL1,LBP,CXCL2,DAPK2
GO:0045670	regulation of osteoclast differentiation	GO_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION	-0.220826281639927	-0.90885800024943	0.632413855887842	0.887700183035228	57	CCL3,TNFSF11,CEBPB,FSHR,CTNNB1,TJP2,CSF1,IL20,TFE3,SLC9B2,ZNF675,CLDN18,CARTPT,MAFB,FSHB,RASSF2
GO:0006939	smooth muscle contraction	GO_SMOOTH_MUSCLE_CONTRACTION	0.239657196245808	0.897765561006967	0.632687978388113	0.887714770843847	43	AGT,NPY1R,ROCK2,SMTN,DRD2,SLC8A1,MYLK,KCNMA1
GO:0050829	defense response to gram negative bacterium	GO_DEFENSE_RESPONSE_TO_GRAM_NEGATIVE_BACTERIUM	0.240961195535589	0.897575223153637	0.63312274368231	0.88795464801444	42	VIP,APP,CD160,LBP,S100A7,SELP,NPY,TNFRSF14,TLR4,RNASE7,ADM,CD4,NOS2
GO:0016482	cytosolic transport	GO_CYTOSOLIC_TRANSPORT	0.19269667568484	0.932501447089069	0.634071279658493	0.888914588642435	187	C2CD4A,UBE2O,CPLX1,DENND5A,SYT9,RAB6A,SYT8,CPLX3,STON2,SYTL2,VAMP2,VPS13A,STX1A,ERC1,ARF1,SYT7,PIK3C3,FAM21C,CADPS,PIKFYVE,RAB6B,KIF16B,VTI1A,ARL1,BET1L,TGOLN2,STX4,RAB41,OPHN1,TBC1D10B,SYT12,RAB9B,SYTL3,P2RX7,DCTN1,RPH3AL,GOSR1,CLTCL1,SORT1,AP3M2,PIP5K1C,GBF1,C2CD4B
GO:0001578	microtubule bundle formation	GO_MICROTUBULE_BUNDLE_FORMATION	-0.224554230808754	-0.906563042681299	0.634516501687544	0.889168419933502	52	CAPN6,C11orf63,KIF20A,GAS2L1,CCDC114,MARK4,TTLL1,DNAH1,SPEF2
GO:0006520	cellular amino acid metabolic process	GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS	0.184174919452231	0.942258145538082	0.634980199284619	0.889447919597182	296	TARS2,IVD,TPH2,ATP7A,HIBCH,STAT5B,DMGDH,PARS2,ATPIF1,MCCC2,CKMT2,DDO,AMT,AUH,ALDH7A1,PPAT,OTC,FOLH1B,CKB,DLD,EARS2,THNSL1,MTR,THNSL2,LRRC47,TYR,MTHFR,OGDH,HAAO,FPGS,ASRGL1,LARS2,NMNAT3,SIRT4,SARDH,PSPH,IDO1,CKM,EGLN1,MARS,IARS2,NFS1,ACAT1,GLUD1,AIMP2,GOT2,ADSSL1,GATM,WARS,ART4,GSS,SLC25A32,SLC6A8,PRODH2,EIF2B4,GOT1,BCKDK,HOGA1,GCDH,MRPL39,SLC7A5,ASNS,SMS,DBT,GLUD2,CAD,MARS2,UPB1,NAALAD2,DLST,QRSL1,TARS,SHMT2,SARS2,NMNAT2,TH,NIT2
GO:0000302	response to reactive oxygen species	GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES	0.193352397416986	0.931272676138233	0.635581275805462	0.889504174809075	180	BAD,GSR,ATP7A,SCGB1A1,TXN2,CYP2E1,HDAC2,IL18BP,TXNRD1,GUCY1B3,MTR,PPIF,GJA3,GSK3B,PTPRK,PTPRN,SLC8A1,EGLN1,EZH2,PPP5C,PXN,EP300,ADA,SETX,GPX5,FOXO1,KCNA5,S100A7,PRDX2,SOD2,HBA1,PARK7,HDAC6,CDK1,KPNA4,ETS1,CYBA,SOD1,TPO,CCS,HYAL1,IMPACT,HYAL2,FXN,GNAO1
GO:0010507	negative regulation of autophagy	GO_NEGATIVE_REGULATION_OF_AUTOPHAGY	0.235203156700844	0.897826302562397	0.635786710772329	0.889504174809075	47	HERC1,UBQLN4,SNRNP70,LRRK2,TSC1,GOLGA2,PINK1,TLK2,RASIP1,MTOR,NPC1,KIF25
GO:0043535	regulation of blood vessel endothelial cell migration	GO_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.233237486405584	0.898328957193307	0.635901123595506	0.889504174809075	49	AMOT,PDGFB,HDAC9,CSNK2B,STARD13,AGTR2,DLL4,AMOTL1,CCR2,VEGFA,HSPB1,PLCG1,HMGB1
GO:0007176	regulation of epidermal growth factor activated receptor activity	GO_REGULATION_OF_EPIDERMAL_GROWTH_FACTOR_ACTIVATED_RECEPTOR_ACTIVITY	0.276642883757905	0.881169657418275	0.63607740605034	0.889504174809075	22	FBXW7,APP,ADRA2C,ZGPAT,TGFA,SOCS4,EGF,EREG,ADRA2B,SHC1
GO:0018198	peptidyl cysteine modification	GO_PEPTIDYL_CYSTEINE_MODIFICATION	-0.275167592825544	-0.879315268686843	0.636373525956225	0.889548707794291	20	RAB3B,MOCS3,GOLGA7,MAP6D1,S100A9,HMBS
GO:0051881	regulation of mitochondrial membrane potential	GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_POTENTIAL	0.232198775897499	0.898182906349	0.637445693152849	0.889961990215177	50	BAD,ATPIF1,LRRK2,SLC25A36,PINK1,GSK3B,NDUFS1,PARK7,VCP,P2RX7,SOD1
GO:0042177	negative regulation of protein catabolic process	GO_NEGATIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS	0.208963460440884	0.915331156283776	0.637482923792561	0.889961990215177	96	CSNK2A1,PIN1,N4BP1,MAD2L1,SUFU,GRIN2C,CDK5RAP3,DERL3,TLK2,SHH,OPHN1,YOD1,PARK7,TIMP3,APC,DEDD,PBK,SF3B3,BAG6,SMAD3,SERPINB12,USP14,KLHL22,TPR,MAD1L1,UBXN1,MDM4,SIRT2,NOS2,PLK1,USP44,HSP90AB1,CDKN2A,USP19,ATM,CST3,AGAP2,WAC
GO:0046530	photoreceptor cell differentiation	GO_PHOTORECEPTOR_CELL_DIFFERENTIATION	-0.225921824160963	-0.900888292260227	0.638281091556437	0.889961990215177	49	CNGB1,PRKCI,PDE6C,ROM1,GNAT1,STAT3,TULP1,RDH13,NRL,IFT20,RP1L1,NKD1,GNGT1,SDK2,PRDM1,IFT140
GO:0010517	regulation of phospholipase activity	GO_REGULATION_OF_PHOSPHOLIPASE_ACTIVITY	-0.217633429908635	-0.908492135929416	0.638633286674775	0.889961990215177	61	AVPR1B,FGFR2,LPAR1,CYR61,SNCA,ANXA1,AGTR1,ANGPTL3,EGFR,C5AR1,PDPK1,TXK,LRP1,GNA13,ABL1,RGS2,HPCA,FGF2,HTR2A,ARF4,GPR55
GO:0018195	peptidyl arginine modification	GO_PEPTIDYL_ARGININE_MODIFICATION	-0.2817352222216	-0.87491573504497	0.639224184635388	0.889961990215177	18	PRMT5,PRDM14,PADI4,PRMT8,PADI3,NR1H4,PADI2,PADI1,PRMT2,PADI6,PRMT6,PRMT3
GO:2000831	regulation of steroid hormone secretion	GO_REGULATION_OF_STEROID_HORMONE_SECRETION	-0.278142170926684	-0.876023797603006	0.639276250054303	0.889961990215177	19	RETN,C1QTNF1,AGTR1,POMC,GAL,TMF1
GO:0036151	phosphatidylcholine acyl chain remodeling	GO_PHOSPHATIDYLCHOLINE_ACYL_CHAIN_REMODELING	-0.260578735764208	-0.883915588222297	0.639361912504669	0.889961990215177	25	PLA2G2A,PLA2G16,PLA2G2D,PLA2G4F,LPCAT3,PLB1,PLA2G2F,PLA2G4A
GO:0046148	pigment biosynthetic process	GO_PIGMENT_BIOSYNTHETIC_PROCESS	0.235410715050177	0.894477151312288	0.639450035945363	0.889961990215177	46	COX15,CECR1,ATPIF1,PPAT,TYR,COX10,ALAD,ADA
GO:0060219	camera type eye photoreceptor cell differentiation	GO_CAMERA_TYPE_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION	0.302744160974272	0.869925500058908	0.639528615773527	0.889961990215177	15	PROM1,RP1,GNAT2,SOX9,CABP4
GO:0032835	glomerulus development	GO_GLOMERULUS_DEVELOPMENT	-0.229456809739345	-0.897591421212396	0.639841480714237	0.889961990215177	45	SULF1,OSR1,WT1,BMP4,ANGPT1,SULF2,NPHS1
GO:0046470	phosphatidylcholine metabolic process	GO_PHOSPHATIDYLCHOLINE_METABOLIC_PROCESS	0.223839502307856	0.902038995925931	0.639845453095369	0.889961990215177	61	CHAT,LPIN1,PCYT1A,DBI,CHPT1,PLA2G4C,LCAT,PLA2G5,LPCAT4,PLA2G15,MBOAT2,PCYT1B,PLA2G4E,CETP,PNPLA6,SLC27A1,CHKA,MBOAT1,PLA2G4D,APOA5
GO:0007157	heterophilic cell cell adhesion via plasma membrane cell adhesion molecules	GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES	0.248634504580021	0.888360047094802	0.640592619523723	0.889961990215177	35	IL1RAPL1,NRXN1,CRTAM,CDH2,CBLN1,FAT4,SELP,ITGAL,SMAGP
GO:1902532	negative regulation of intracellular signal transduction	GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION	0.179436080121313	0.945858420843879	0.640806201550388	0.889961990215177	395	TRAP1,CARD8,ELL3,RAPGEF1,DDX3X,PARL,FLCN,PYDC2,WTIP,ITPR1,C1QBP,MFN2,RGS3,DLC1,PAFAH1B1,LRRK2,CALM3,ESR1,PIN1,TSC1,TAOK3,TSC2,DRD2,ARHGEF2,STAMBP,PPIF,WNK2,PINK1,FNIP1,RASAL3,HMGCR,GSK3B,CAV3,PTEN,CDK5RAP3,PRKAA2,NPRL3,VDAC2,RASAL1,ARHGAP35,CD300A,TMEM127,LRTM1,DNAJA3,LAX1,MAPKAPK5,CALM1,RASAL2,FOXO1,GBP1,DUSP19,DUSP21,RNF152,PDCD6,DEPDC5,SOD2,RGS14,SLA2,PARK7,SOCS4,RPS6KA6,NCOR1,MECOM,PIK3IP1,TRIM32,TIMP3,P2RX7,LIMD1,GRINA,HSPB1,FAF1,DUSP3,LEMD2,PBK,LRRTM3,RHOH,IVNS1ABP,NME5,AKT1S1,SCAI,KANK1,HYAL2,DUSP7,TRDN,EPM2A,MAPKAP1,OTUD7A,CHAD,BCL6,TRIM59,CNKSR3,NDUFA13,LITAF,OPA1,NFKBIA,UBE2B,UBR2,TLR4,DUSP4,INPP5F,XDH,DDIT4,VNN1,PAQR3,DUSP26,CRYBA1,GCG,TWIST1,CDC34
GO:0019216	regulation of lipid metabolic process	GO_REGULATION_OF_LIPID_METABOLIC_PROCESS	-0.179950957308388	-0.943875230576103	0.64088412241695	0.889961990215177	252	SERPINA3,C3,APOA2,SMPD3,CNR1,APOC1,CCL19,ACADL,ORMDL2,SLC45A3,BMP2,LSR,LGALS12,CYR61,CIDEA,TSPO,AADAC,SNCA,ANXA1,AGTR1,KLF4,SMPD2,XBP1,GK,ANGPTL3,CCL21,THRSP,AKR1C3,NR4A3,DGAT2,STAR,TNFRSF1A,HCAR2,SCAP,ADIPOQ,BMP5,LEP,GOLM1,PPP2R5A,TNFAIP8L3,PPARG
GO:0006672	ceramide metabolic process	GO_CERAMIDE_METABOLIC_PROCESS	0.21964422438314	0.904771326195642	0.64110510468208	0.889961990215177	68	AGK,CERS4,ST6GALNAC4,ST8SIA6,NSMAF,ST3GAL6,ACER2,ST3GAL3,CLN8,ST3GAL2,NEU3,PLA2G15,SMPD4,ST6GALNAC3,CERS6,CERK,P2RX7
GO:0071901	negative regulation of protein serine threonine kinase activity	GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	-0.195717176441163	-0.925780230303199	0.64124547640444	0.889961990215177	122	CDKN2B,DUSP18,SFN,MAPK8IP1,BMP4,SFRP2,HEXIM1,RGS4,CDKN2C,MEN1,TP73,PYCARD,CEBPA,CDKN1A,ADIPOQ,IRAK3,PRKAR2B,CASP3,SORL1,PRKAR1B,INPP5K,ZNF675
GO:0030858	positive regulation of epithelial cell differentiation	GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION	0.228371142113366	0.897722127010163	0.641494605986997	0.889961990215177	54	TRIM16,BAD,ATOH8,PROM1,ZEB2,CDH5,CYP27B1,PRKCH,PTCH1,NCOA3,PAX6,SOX9,LHX1,PTCH2,FOXJ1,MED1
GO:0021697	cerebellar cortex formation	GO_CEREBELLAR_CORTEX_FORMATION	0.278526153760808	0.876629108941315	0.642249414022849	0.889961990215177	21	HERC1,ATP7A,NRXN1,CBLN1,LDB1,LHX1,PROX1
GO:0097722	sperm motility	GO_SPERM_MOTILITY	-0.234616451538717	-0.893413901190653	0.642732362821948	0.889961990215177	40	DNAH1,CACNA1I,PLTP,TMF1,AKAP4,DNAH5,LRRC6,PGK2,CATSPER1,DPCD,PRM3,LDHC,ROPN1B,CATSPER3,ATP1A4,TEKT2,CCDC40,SORD,DNAJA1,DNAH11,SMCP,TNP1,DDX4
GO:1901796	regulation of signal transduction by p53 class mediator	GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	-0.190274803694833	-0.929570983752479	0.642934809469678	0.889961990215177	150	NOC2L,TAF9B,KDM1A,RBBP8,HEXIM1,RPA3,MUC1,PRMT5,SSRP1,BANP,MBD3,TP73,TBP,TAF10,TP53RK,UBA52,RRM2B,RPA2,CDK5,TAF4B,BDKRB2,PSMD10,CHEK2,AURKB,CHD3,BARD1,TPX2,TRIAP1,MDM2,MIF,POU4F2,MAPK11,UBB,SIRT1,NBN,CHD5,TAF12
GO:0009415	response to water	GO_RESPONSE_TO_WATER	-0.280815176512015	-0.872058575539214	0.643298298840611	0.889961990215177	18	KRT8,WNT10B,FAS,PKD2
NA	cellular protein complex localization	GO_CELLULAR_PROTEIN_COMPLEX_LOCALIZATION	0.275056108591176	0.87611542247439	0.643534458949384	0.889961990215177	22	GSG2,KLHL21,MIOS,WASL,SMAD7,STXBP6
GO:0051701	interaction with host	GO_INTERACTION_WITH_HOST	-0.19647676411989	-0.922366348094653	0.643626007626587	0.889961990215177	116	CLDN1,CD55,TYRO3,DPP4,EFNB3,C9,WWP2,HAVCR1,SLC10A1,ANPEP,SLC25A6,KPNA7,TYMS,VAMP8,CLEC5A,SELPLG,EIF2AK4
GO:0007200	phospholipase c activating g protein coupled receptor signaling pathway	GO_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	-0.207627211961201	-0.913747586994725	0.643724224702346	0.889961990215177	80	MC3R,DRD5,LTB4R,RXFP3,LPAR1,OPRM1,TACR1,AGTR1,HCRTR2,P2RY4,HRH4,ADRA1D,EDNRB,OPRD1,CHRM4,F2RL3,F2R,HCRT,EDN1
GO:0060193	positive regulation of lipase activity	GO_POSITIVE_REGULATION_OF_LIPASE_ACTIVITY	0.222090676898925	0.900998687938585	0.643995184818014	0.889961990215177	63	AGT,PLCB2,FLT1,ESR1,PLA2G5,ADCYAP1R1,ARL1,FGFR1,PRKCZ,CAMK2B,NMUR2,PTAFR,PRKCE,CALCR,MARCKS,LPAR2,ABL2,APOA5,SELE
GO:0032388	positive regulation of intracellular transport	GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT	0.181669573677762	0.941216969697387	0.644023926390051	0.889961990215177	333	EHD1,PRKACA,BAD,PIK3R1,RBCK1,AKT2,FBXW7,GPHA2,DYNLL2,ATPIF1,RAB21,EDEM2,CALM3,GZMB,ITGAX,RNF31,CAPN3,XCL1,VAMP2,C8orf4,ADCYAP1R1,CXCL11,PINK1,STARD7,BAP1,ARF1,PLAGL2,ABLIM3,VPS11,GSK3B,AKAP6,JAK2,DDX58,CSF3,HUWE1,CXCR3,CYB5R1,PSMB7,KAT2A,UBR5,NMT1,SHH,CALM1,SAE1,XPO4,KHDRBS1,EP300,ERBB4,PPP3R1,PPP1R13B,IL18R1,IL4,NCBP2,TNF,SEMA5A,TMEM173,EMD,ARIH2,CDK1,PSMD8,P2RX7,USP36,ANK3,CXCL9,ADORA2B,RDX,PLCG1,KANK1,HYAL2,HTT,SMAD3,TRDN,OAZ1,TPR,BID,KCNN3,JPH2,BAMBI,BCAS3,MAPK8,RANBP3,EGF,TLR4,TGFB3,MED1,YWHAG,SCP2,BAK1,EDA,PRKCQ,WBP11,MTMR2,JUP,TP53BP2
GO:0045907	positive regulation of vasoconstriction	GO_POSITIVE_REGULATION_OF_VASOCONSTRICTION	0.248058354230097	0.886301487471884	0.644028358480276	0.889961990215177	35	TRPM4,NPY1R,HRH2,ADRA2C,GJA1,GJA5,PTAFR,CD38
NA	regulation of multicellular organismal metabolic process	GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS	-0.24228098330573	-0.888054673383507	0.644072313774264	0.889961990215177	34	BMP4,RETN,CTGF,FAP,ERRFI1,F2,PPARG,RAPGEF3
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	0.266928452472064	0.878809267899946	0.64441834431374	0.89007474228972	25	FLT1,GRB10,ITGB3,VEGFB,TMEM204,PDCD6,VEGFA
GO:0002700	regulation of production of molecular mediator of immune response	GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	-0.203006548705246	-0.915814050758655	0.645216898481593	0.890315834278067	92	RBP4,APOA2,FFAR3,WNT5A,KLK7,ANGPT1,GATA3,MZB1,CLCF1,XBP1,NR4A3,IRAK3,WHSC1,KLK5,NLRP3,IL5
GO:0009411	response to uv	GO_RESPONSE_TO_UV	-0.196306365587589	-0.921566406825957	0.645339576193464	0.890315834278067	116	NOC2L,KDM1A,AQP1,POLH,SCARA3,CRIP1,HIST3H2A,MEN1,CAT,TP73,CDKN1A,EGFR,CASP3,GTF2H2,KIAA0101,YY1,MME,DDB2,ZBTB1,EIF2AK4,DCUN1D3,XPC,AURKB,BAX,CDC25A,TRIAP1,MDM2,MYC,ELANE,SIRT1,PCNA,USP1,BCL2
GO:1902624	positive regulation of neutrophil migration	GO_POSITIVE_REGULATION_OF_NEUTROPHIL_MIGRATION	0.263843633941585	0.877336525133684	0.646106455930618	0.890315834278067	26	C1QBP,XCL1,LBP,CXCL2,DAPK2
GO:0051955	regulation of amino acid transport	GO_REGULATION_OF_AMINO_ACID_TRANSPORT	0.266555093950227	0.87758005862607	0.646143399827494	0.890315834278067	25	ATP1A2,SLC6A1,RAB3GAP1,GABBR1,NPY5R,P2RX7,SLC38A3,DPYSL2,TMEM27,ARG1
GO:0030888	regulation of b cell proliferation	GO_REGULATION_OF_B_CELL_PROLIFERATION	-0.221275153102037	-0.900739162995609	0.64627164084155	0.890315834278067	54	TCF3,TNFRSF21,MZB1,CLCF1,BST1,CDKN1A,SLC39A10,CASP3,CHRNB2,IL5,AHR,MIF,PAWR,IL10,BCL2,CD81,PRDM1,TNFRSF13C
NA	regulation of ion homeostasis	GO_REGULATION_OF_ION_HOMEOSTASIS	0.191942507585588	0.927709835473163	0.646445073781488	0.890315834278067	185	AGT,PRKACA,TRPM4,ANK2,ITPR1,TRPV1,SCN5A,LRRK2,CALM3,RYR2,WNK1,TPCN1,NEDD4L,CAPN3,XCL1,ATP1A2,DRD2,HRC,WNK2,ADCYAP1R1,CXCL11,GJA1,AKAP6,CAV3,DMD,CXCR3,PLN,SLC8A1,AGTR2,CALM1,CACNA1C,GJA5,CA2,P2RX7,CYBA,ANK3,CXCL9,PLCG1,SLC30A1,SMAD7,HTT,FGF12,TRDN,CA7,NPFF,JPH2,PRKCE
GO:0000070	mitotic sister chromatid segregation	GO_MITOTIC_SISTER_CHROMATID_SEGREGATION	0.212524562735021	0.907240134699123	0.646481235585995	0.890315834278067	83	GSG2,SPAG5,POGZ,AKAP8,VPS4A,NCAPH,MAD2L1,CHMP7,TTN,SMC1A,SMC2,MAU2,KIFC1,NAA50,NCAPD3,DLGAP5,KIF25,CEP57L1,CHMP6,KLHL22,ESPL1,AKAP8L,DIS3L2,CHMP1B,PAPD7,PHF13,KPNB1,CHMP4B,PLK1,CHMP4C,KIF23,NCAPD2,PPP2R1A
GO:0032094	response to food	GO_RESPONSE_TO_FOOD	0.284565745655501	0.87080456359945	0.646708917055815	0.890315834278067	19	CLPS,HSD11B2,GHSR
GO:0001895	retina homeostasis	GO_RETINA_HOMEOSTASIS	-0.216938450257047	-0.902936647102125	0.647388401024515	0.890384976583092	60	SLC28A3,AZGP1,CNGB1,IQCB1,POTEE,ACTG1,USH1G,TULP1,AIPL1,CDH3,PIGR,IGKC,RP1L1,WDR36,BBS10,CST4,POTEF,LYZ
GO:0030857	negative regulation of epithelial cell differentiation	GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION	-0.238612104170539	-0.886913175369414	0.647592307863716	0.890384976583092	36	OSR1,HOXA7,GRHL2,NKX6-3,CTNNB1,MSX2
GO:0035137	hindlimb morphogenesis	GO_HINDLIMB_MORPHOGENESIS	-0.23748186668111	-0.888231524360798	0.64789456048252	0.890384976583092	37	GDF5,OSR1,BMP4,CTNNB1,MSX2,FGF4,RSPO2
GO:0051402	neuron apoptotic process	GO_NEURON_APOPTOTIC_PROCESS	-0.240230320020937	-0.886993737328453	0.648048541963016	0.890384976583092	35	SDIM1,TNFRSF21,BOK,CASP3,CDK5,FAS,BAX,GRIK2,NAE1,PSEN1,BCL2
GO:0008360	regulation of cell shape	GO_REGULATION_OF_CELL_SHAPE	-0.193689642495955	-0.924196798969248	0.648151765222911	0.890384976583092	129	PDPN,MYL12B,EZR,CCL3,EPB42,KDR,LPAR1,ARHGAP18,ANXA1,PLXNB2,PARVA,F2,BAIAP2,TBCCD1,RHOQ,TPM1,CDC42EP1,CFDP1,C21orf2,SEMA3E,MSN,WIPF2,SEMA4A,PALMD,GNA13,CSNK1G3,PLXNB1,DLG1
GO:0008037	cell recognition	GO_CELL_RECOGNITION	-0.194424264444247	-0.923955675482635	0.648346279740095	0.890384976583092	126	CNR1,ZAN,CCL19,ZP1,EFNB3,CD200,COLEC12,GAP43,RTN4,SEMA3A,CCL21,ADAM30,ATP8B3,ROBO2,TULP1,FCN3,IGHG4,IGHG2,IGHG1,IZUMO1,IGHD,IGKC,NRCAM,IGLL1,IGLC1,DLG1,CCT5,CLGN,OPCML,CATSPER1,ADAM2,PCDH12,CD6,CRTAC1,VCAN,B4GALT1,ZP4,SPA17,IGHA1,CADM3,PTPRZ1,FCN2,CD5,PVR,CCT2,CCR7,EPHB1,DOCK2,IGLL5,CNTNAP2,PCSK4,CXCR4,CATSPER3
GO:0030522	intracellular receptor signaling pathway	GO_INTRACELLULAR_RECEPTOR_SIGNALING_PATHWAY	0.196136135738314	0.922060089621026	0.650141024780069	0.892485599269866	151	NR1I2,PPARD,ESRRA,NR2F6,FLT1,PPARA,ESR1,UBE2N,RNF14,SP100,NKX3-1,JAK2,DDX58,MED24,MED12,RXRB,UBR5,AR,RXRG,MED17,RHOXF1,ESR2,THRAP3,IKBKB,FHL2,SLA2,RXRA,NCOA3,ESRRG
GO:0032369	negative regulation of lipid transport	GO_NEGATIVE_REGULATION_OF_LIPID_TRANSPORT	0.270552152523241	0.872327415977883	0.650582271040741	0.892727241876532	23	AKT2,ITGB3,APOC3,AGTR2,SHH,NFKB1,EGF
GO:0030890	positive regulation of b cell proliferation	GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION	-0.237003921791131	-0.886443911166918	0.651066681559254	0.893027893287876	37	TCF3,CLCF1,BST1,CDKN1A,SLC39A10,CHRNB2,IL5,MIF,BCL2,CD81,TNFRSF13C,SASH3,WNT3A,IL7
GO:0040019	positive regulation of embryonic development	GO_POSITIVE_REGULATION_OF_EMBRYONIC_DEVELOPMENT	0.258525788309484	0.875996687167671	0.652409252994423	0.893957983894701	28	AMOT,CLASP1,PAFAH1B1,OSR2,SIX1,SHH
NA	negative regulation of g protein coupled receptor protein signaling pathway	GO_NEGATIVE_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY	0.24366618740547	0.882573787189217	0.652624146858084	0.893957983894701	37	ADRB2,DRD2,GIPR,ADA,GRK6,RGS13,GRK4,RPH3AL,GPRASP1,ADM,KLK14,ADRB3,DNM2,DRD3,CCL5
GO:0048103	somatic stem cell division	GO_SOMATIC_STEM_CELL_DIVISION	-0.272124993172849	-0.869592451026364	0.652756625038075	0.893957983894701	20	FGFR2,RAB10,FGF13,DOCK7,WNT7A,ASPM,WNT3A,DCT
GO:0001919	regulation of receptor recycling	GO_REGULATION_OF_RECEPTOR_RECYCLING	0.283345033838245	0.867069042239146	0.652842635831295	0.893957983894701	19	ARAP1,PCSK9,KIF16B,RAMP3
GO:0034605	cellular response to heat	GO_CELLULAR_RESPONSE_TO_HEAT	0.252807256191525	0.878297182030632	0.653104378577418	0.893957983894701	31	HDAC2,C8orf4,CETN1,FGF1,ANO1,STAC,PDCD6,TFEC,TPR,EIF2S1,CLPB,NF1,ATXN3
GO:0032273	positive regulation of protein polymerization	GO_POSITIVE_REGULATION_OF_PROTEIN_POLYMERIZATION	0.212629683582805	0.903762600388778	0.653352953542148	0.893957983894701	81	TUBGCP5,CLASP1,CLIP1,TUBGCP2,CCL24,PINK1,CAV3,SPIRE1,CSF3,ACTR3B,FAM21C,MTOR,CDKN1B,BAG4,JMY,TUBGCP6,C15orf62,MLST8,PRKCE,TUBGCP3,PFN2,ARF6
GO:0006979	response to oxidative stress	GO_RESPONSE_TO_OXIDATIVE_STRESS	0.181692297662894	0.938418040644473	0.65378945199182	0.893957983894701	324	BAD,GSR,ATP7A,EPAS1,NDUFS2,SCGB1A1,TXN2,ANKRD2,MSRB2,CYP2E1,HDAC2,NDUFB4,APP,ALS2,LRRK2,IL18BP,CHD6,CPEB2,TXNRD1,GUCY1B3,GPX6,MTR,PPIF,PINK1,ABCC2,GJA3,GSK3B,JAK2,LIAS,PTPRK,UCN,CLN8,PTPRN,STC2,SLC8A1,ERCC1,EGLN1,EZH2,PPP5C,PXN,ALAD,EP300,STX4,ADA,SETX,GPX5,LONP1,TXNL1,FOXO1,KCNA5,S100A7,PRDX2,SOD2,RGS14,GSS,HBA1,PARK7,HDAC6,CDK1,IPCEF1,KPNA4,ETS1,CYBA,SOD1,ZNF622,TPO,CCS,HYAL1,IDH1,IMPACT,NDUFS8,CD38,NFKB1,HYAL2,FXN,GNAO1,GAB1,CD36
GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.265094989082593	0.872772951411012	0.653869446330587	0.893957983894701	25	AMOT,PDGFB,HDAC9,AMOTL1,CCR2,VEGFA,HSPB1,PLCG1
GO:0097237	cellular response to toxic substance	GO_CELLULAR_RESPONSE_TO_TOXIC_SUBSTANCE	-0.259876289043333	-0.872458104596594	0.655079392929204	0.895248573528097	24	CRIP1,STAR,HIF1A,RAB10,PLA2G4F,HMBS,OPRD1,MDM2
GO:0015669	gas transport	GO_GAS_TRANSPORT	0.294434158400835	0.860317479790728	0.655701143016448	0.895426912310264	16	RHAG,HBM,HBA1,IPCEF1,CA2,CYGB,HBB
GO:0046134	pyrimidine nucleoside biosynthetic process	GO_PYRIMIDINE_NUCLEOSIDE_BIOSYNTHETIC_PROCESS	0.272638774847091	0.868415672102334	0.655741930732264	0.895426912310264	22	TK1,UPP2,UCKL1,NME6,NME5,CAD,DHODH,UMPS
GO:0043604	amide biosynthetic process	GO_AMIDE_BIOSYNTHETIC_PROCESS	0.176900765943998	0.944032984222016	0.656367342559811	0.89591746758164	452	CPEB3,PABPC4,SLC25A28,SLC25A17,TARS2,PTCD3,SLC25A45,AURKAIP1,GFM1,SLC25A2,EIF2B5,AGK,CERS4,MRPL4,PARS2,MRPL16,ATPIF1,NDUFA7,RPL3L,SLC25A30,METTL17,EEF1A2,MRPL41,RMND1,MRPL14,OTC,HAGH,ST6GALNAC4,MRTO4,ST8SIA6,CPEB2,EARS2,MRPL19,MRPS15,APEH,SLC25A36,NACA,MRPL53,LRRC47,PCBP2,IGHMBP2,SLC25A11,FPGS,ST3GAL6,SLC25A3,LARS2,SLC25A4,MTIF3,DMD,ST3GAL3,CLN8,ST3GAL2,MRPL15,SMPD4,MRPL27,MRPS28,GTF2H3,ABCF1,MARS,IARS2,MRPL24,MRPL35,RPL35A,SLC25A41,MRPL20,AIMP2,GUF1,ST6GALNAC3,MRPL17,EIF4E2,MRPL12,CERS6,WARS,HBS1L,GGT7,GSS,RPL29,SLC25A32,MRPL37,RPS14,MRPL51
GO:0009812	flavonoid metabolic process	GO_FLAVONOID_METABOLIC_PROCESS	0.294148527692244	0.859482885419271	0.656946380447914	0.896344352082561	16	UGT2A3,UGT3A1,UGT3A2,UGT2B11,CYP1A1,PPARGC1A,SULT1A1,POR
GO:0045070	positive regulation of viral genome replication	GO_POSITIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION	-0.250401776707947	-0.874849317101553	0.657942935322285	0.897069569160998	28	PPIB,TARBP2,PABPC1,TOP2A,TRIM38,PPIH
GO:2001234	negative regulation of apoptotic signaling pathway	GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY	-0.185023483400113	-0.928990459466622	0.658401230986555	0.897069569160998	181	NOC2L,SCG2,MAPK8IP1,TAF9B,KDM1A,TGFBR1,SFRP2,MUC1,CREB3L1,TXNDC12,ACVR1,XBP1,CTNNB1,FIGNL1,NONO,RIPK1,PELI3,NLE1,HIF1A,TRADD,RRM2B,PLAUR,BMP5,TPT1,MAGEA3,SH3RF1,BDKRB2,DAPK1,GDNF,FAS,PRELID1,HGF,PSMD10,THBS1,BAX,HMGB2,TRIAP1
GO:0042149	cellular response to glucose starvation	GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION	-0.246876950538714	-0.877292342527029	0.658646716394785	0.897069569160998	30	XBP1,TBL2,SH3GLB1,EIF2AK3,PICK1,CPEB4,BHLHA15,SLC2A1,NFE2L2,IFI16,BCL2,PIK3R4
GO:1904377	positive regulation of protein localization to cell periphery	GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY	-0.2400197081292	-0.879766214417702	0.659130280282503	0.897069569160998	34	EZR,ITGA3,PRKCI,ARHGEF16,ANXA13,RHOG,EPHA2,PDPK1,DLG1,WNK3
GO:0043388	positive regulation of dna binding	GO_POSITIVE_REGULATION_OF_DNA_BINDING	0.239256423496538	0.88156666548508	0.659379968203498	0.897069569160998	40	CALM3,HAND2,HIPK2,JAK2,KAT2A,CALM1,EP300,ACD,PARK7,HMGB1,EGF,TWIST1,MYOCD,SIRT2
GO:0042509	regulation of tyrosine phosphorylation of stat protein	GO_REGULATION_OF_TYROSINE_PHOSPHORYLATION_OF_STAT_PROTEIN	-0.212895786642286	-0.899552542527307	0.659381281334473	0.897069569160998	65	IL18,ARL2BP,PTPN2,SOCS1,CLCF1,STAT3,IL6ST,IL20,TNFRSF1A,LEP,IL24,FLT3,HNF4A,PTGER4,SOCS3
GO:0070663	regulation of leukocyte proliferation	GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION	-0.182953731535566	-0.931896465263555	0.659526350561569	0.897069569160998	200	CD55,TCF3,CCL19,IL18,BMP4,TNFRSF21,CEBPB,HLA-DRB5,MZB1,SOX11,IL27,ANXA1,TACR1,CLCF1,PLA2G2D,CTNNB1,BST1,IL6ST,PYCARD,RIPK2,CSF1,CDKN1A,SLC39A10,RIPK3,CASP3,LEP,TNFSF9,CHRNB2,LILRB2
GO:0048066	developmental pigmentation	GO_DEVELOPMENTAL_PIGMENTATION	0.244087042669271	0.877929099539702	0.659609977324263	0.897069569160998	36	MREG,C10orf11,ZEB2,TYR,USP13
GO:0021514	ventral spinal cord interneuron differentiation	GO_VENTRAL_SPINAL_CORD_INTERNEURON_DIFFERENTIATION	0.288941158887229	0.858360871451343	0.660058027079304	0.897316364761283	17	GLI2,SUFU,DLL4,PAX6,NKX2-2,GATA2,ASCL1,LHX3,NKX6-2
GO:0050953	sensory perception of light stimulus	GO_SENSORY_PERCEPTION_OF_LIGHT_STIMULUS	-0.182687547426147	-0.931342871634679	0.660925234357137	0.898132555044863	201	RBP4,CNGB1,IRX5,RDH10,LRAT,EFEMP1,CRYBB3,SIX6,BEST1,GUCY2F,BBS7,PDE6C,OCLM,ROM1,PRPH2,GNAT1,USH1G,GPR143,EML2,CACNA1F,OPN1LW,RDH8,ZIC2,TULP1,ATF6,AIPL1,CDH3,CHRNB2,NRL,TULP2,ZNF513,PRCD,MYO3A,CACNB4,RS1,OAT,CHM,GUCY2D,GRK7,NYX,RP1L1,GJD2,WDR36,GUCA1A,IMPG2,FAM161A,BBS10,SFRP5,CRYBB1,EYS,LAMC3,GRM6,VSX2,COL11A1,GRM8,CYP1B1,KRT12,CRYGC,ATP8A2,SLC45A2,PDCL,RD3,PDE6G,PDE6A,RCVRN,OPN1SW,LUM,RAX2,MYO3B,CRYGD,GRK1,RP2,POU6F2,BBS5
GO:0048488	synaptic vesicle endocytosis	GO_SYNAPTIC_VESICLE_ENDOCYTOSIS	-0.28480429466019	-0.855765237851444	0.66218585622443	0.898143759174258	16	SNCA,CANX,CDK5,SYT5,SYT1,SH3GL2,ITSN1
GO:0044273	sulfur compound catabolic process	GO_SULFUR_COMPOUND_CATABOLIC_PROCESS	-0.23648871914358	-0.879020624556291	0.662299173295898	0.898143759174258	36	FMOD,HPSE,IDUA,GGT1,AGXT,DCN,VCAN,LUM,PRELP,ACOT7,NUDT7,HEXA,AHCY,NCAN,HYAL4,OMD,OGN
GO:0030322	stabilization of membrane potential	GO_STABILIZATION_OF_MEMBRANE_POTENTIAL	-0.284752136319648	-0.85560851516314	0.662488906206031	0.898143759174258	16	KCNK16,KCNK15,KCNK1,KCNN4,KCNK2
GO:0035116	embryonic hindlimb morphogenesis	GO_EMBRYONIC_HINDLIMB_MORPHOGENESIS	0.254467865964327	0.869704447303151	0.663040502308942	0.898143759174258	29	GNAS,OSR2,CHD7,SHH,AFF3,ALX3,FGF8,TBX3,MSX1,MED1,ZBTB16,TWIST1,RARB
GO:0022602	ovulation cycle process	GO_OVULATION_CYCLE_PROCESS	-0.204781885708903	-0.905232074250168	0.663077749492024	0.898143759174258	82	BMP4,FGF7,CEBPB,FSHR,FANCF,SGPL1,BMPR1B,SLIT3,ROBO2,MSTN,LEP,ADCYAP1,BAX,AHR,AFP,FSHB,GPR149,FOXO3,INHBA,SIRT1,FOXL2,MMP19,MMP14,BCL2,PLA2G4A
GO:0007219	notch signaling pathway	GO_NOTCH_SIGNALING_PATHWAY	0.203785839026213	0.905840514834082	0.66373584775801	0.898143759174258	105	DNER,TBX2,NOTCH3,APP,CREBBP,SPEN,PGAM2,CDH6,IFT172,WDR12,SEL1L,NCSTN,PLN,TGFBR2,PSENEN,DLL4,EP300,DTX1,KCNA5,DLL3,CDKN1B,CNTN1,SOX9,HEY2,GOT1,ADAM10
GO:0006293	nucleotide excision repair preincision complex stabilization	GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_STABILIZATION	0.277576274274318	0.861625905728629	0.663915618060696	0.898143759174258	20	CUL4A,ERCC1,GTF2H3,ERCC4,GTF2H5
GO:2000573	positive regulation of dna biosynthetic process	GO_POSITIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	0.222604825067228	0.887894952881642	0.663967251045653	0.898143759174258	58	HMBOX1,PDGFB,PARM1,GSK3B,OBFC1,MAP3K4,DDX39B,MAPKAPK5,TCP1,ACD,RFC3,MAPK1,CCT3,CCT7,WRAP53,CCT4,PRKCQ,NOX4,PKIB,MAP2K7
GO:0002691	regulation of cellular extravasation	GO_REGULATION_OF_CELLULAR_EXTRAVASATION	-0.266439765072173	-0.862589423315138	0.66417861585805	0.898143759174258	21	CCL28,CCL21,RIPK3,PDGFD,PTGER4,PAWR
GO:0009895	negative regulation of catabolic process	GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS	-0.184645084558654	-0.927090544347048	0.664203011881038	0.898143759174258	181	TIMP1,APOA2,CNR1,APOC1,PTPN3,DAP,HP,MET,SCFD1,ZKSCAN4,CIDEA,TSPO,SNCA,ANXA2,BANP,STAT3,TOB1,GRIN2A,PABPC1,EGFR,USP25,HCAR2,FBP1,IRAK3,LEP,ERLEC1,TEX14,FMN2,MTM1,HGF,SIRT6
GO:0051642	centrosome localization	GO_CENTROSOME_LOCALIZATION	0.28792999292772	0.855356988939316	0.664410058027079	0.898143759174258	17	NDE1,PAFAH1B1,NIN,GPSM2
GO:1902105	regulation of leukocyte differentiation	GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	-0.181218712173207	-0.932340716121974	0.664860144350551	0.898143759174258	216	PRKCA,CCL3,TNFSF11,CCL19,RARA,CYP26B1,BMP4,PTPN2,HOXA7,GATA3,CEBPB,FSHR,IL27,ANXA1,XBP1,CTNNB1,TJP2,RIPK2,RIPK1,CSF1,IL36B,IL20,IRF7,IRF4,TFE3,ADIPOQ,TNFSF9,LILRB2,RAG1,ZBTB1,ATP11C,FAS,PGLYRP1,PRELID1,SLC9B2,ZNF675,CLDN18,NLRP3,IL5,SART1,NKAP,CARTPT,IL2RA,MAFB,FSHB,MYC,TESC,RASSF2,TRIB1,INHBA,IL4R,CD46,PF4,MMP14,PGLYRP2,ZAP70,PRDM1,JUN,GPR55,TLR3
GO:0045923	positive regulation of fatty acid metabolic process	GO_POSITIVE_REGULATION_OF_FATTY_ACID_METABOLIC_PROCESS	-0.243876362738716	-0.873548410390257	0.665071770334928	0.898143759174258	31	SLC45A3,ANXA1,NR4A3,ADIPOQ,PPARG,NR1H3,FABP1
GO:0072488	ammonium transmembrane transport	GO_AMMONIUM_TRANSMEMBRANE_TRANSPORT	-0.26300609606042	-0.862252645239	0.665404565450526	0.898143759174258	22	AQP1,SLC22A4,SLC22A3,SLC6A3,RHCE
GO:0015931	nucleobase containing compound transport	GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT	0.191560863112125	0.919690779000991	0.665652636478489	0.898143759174258	176	SLC25A17,NOL6,POM121,NCBP1,SMG6,XPO7,SLC29A2,TSC1,SLC25A36,NUP85,QKI,SMG1,GJA1,RAE1,DDX39B,SRSF4,CPSF1,NUP188,SLC35B1,NCBP2,HNRNPA2B1,RNPS1,SRSF1,ALKBH5,P2RX7,RBFOX1,ENY2,HTT,TPR,AAAS,PARP11,DHX38,NXF3,CKAP5,RBM8A,POM121C,MRPL18,SLC25A26,FLOT1,CHTOP
GO:0009615	response to virus	GO_RESPONSE_TO_VIRUS	0.187034659775536	0.924099984253924	0.66576748900551	0.898143759174258	220	ADAR,DDX3X,BAD,RSAD2,UNC13D,IFI44L,GLI2,IFI44,XCL1,OPRK1,PCBP2,ABCF3,HERC5,SERINC5,ADARB1,HMGA1,OAS2,EXOSC4,DDX58,CD8A,CFL1,IFIT2,POLR3F,DCLK1,CD40,IFIT1,OASL,OAS3,IRF1,OAS1,GBP1,IKBKB,TNF,TMEM173,APOBEC3D,MICA,BANF1,HSPB1,HYAL1,CXCL9,CHRM2,IVNS1ABP,APOBEC3H,HYAL2,POLR3K,PSMB9,POLR3H,LILRB1,APOBEC1,IFNA21,TNFSF4,CYP1A1,DDIT4,ABCC9,FOSL1,MEF2C,C19orf66,IFNA4,DDX60,TICAM1
GO:0034314	arp2 3 complex mediated actin nucleation	GO_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION	-0.288812542437777	-0.850832285612231	0.665930783715343	0.898143759174258	15	ARPC5,ACTR3
GO:0097186	amelogenesis	GO_AMELOGENESIS	-0.276041951287183	-0.857235544811326	0.666096001733666	0.898143759174258	18	FAM20A,MMP20,MSX2,FAM20C,WDR72,ITGB4
GO:0042098	t cell proliferation	GO_T_CELL_PROLIFERATION	0.247629822716211	0.872992876915225	0.666399416909621	0.898143759174258	33	RC3H2,CRTAM,NCSTN,PSMB10,P2RX7,MALT1,LILRB1,TNFSF4,SATB1,PIK3CG,CCND3,PPP3CB,RC3H1
GO:0043649	dicarboxylic acid catabolic process	GO_DICARBOXYLIC_ACID_CATABOLIC_PROCESS	0.296272743616073	0.851330092757561	0.66655514043012	0.898143759174258	15	DDO,GLUD1,GOT2,ACOT8,GOT1,GLUD2
GO:0048521	negative regulation of behavior	GO_NEGATIVE_REGULATION_OF_BEHAVIOR	0.291856950482009	0.852787045707727	0.666889694266332	0.898143759174258	16	DRD2,UCN,ADA,ESR2
GO:0050000	chromosome localization	GO_CHROMOSOME_LOCALIZATION	-0.219695799252985	-0.890560139191592	0.666984559491371	0.898143759174258	53	KIF2C,KIF18A,KATNB1,CEP55,ACTR3,SPICE1,CCNB1,CDCA8,FMN2,CHMP5
GO:0017158	regulation of calcium ion dependent exocytosis	GO_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS	-0.205329570409317	-0.9036358853349	0.667070528204292	0.898143759174258	80	SYT4,NLGN1,SYN1,RIMS4,SYTL1,SYT17,TRIM9,IQCF1,RPH3A,C2CD4D,STXBP3,SYT6,CDK5,CACNA1I,UNC13B,KCNB1,SYT5,STXBP1,SPINK1
GO:0000715	nucleotide excision repair dna damage recognition	GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DAMAGE_RECOGNITION	0.270401784043857	0.861290354461926	0.667562740512972	0.898447094988669	22	CUL4A,COPS6,COPS7A,COPS7B
GO:0021846	cell proliferation in forebrain	GO_CELL_PROLIFERATION_IN_FOREBRAIN	-0.25530054755533	-0.866011315175165	0.668102217046428	0.898813774012101	25	FGFR2,LHX5,POU3F2,POU3F3,PCM1,DOCK7
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	GO_POSITIVE_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL	0.242642718382757	0.872734172736392	0.668662131519274	0.899207644703906	36	CALM3,CAPN3,XCL1,CXCL11,AKAP6,CXCR3,CALM1,CXCL9,PLCG1,HTT,TRDN,JPH2
GO:0046637	regulation of alpha beta t cell differentiation	GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	-0.22486024338468	-0.88421089372599	0.669041071187052	0.899357925565342	46	CCL19,RARA,GATA3,IL27,ANXA1,RIPK2,IRF4
GO:0014072	response to isoquinoline alkaloid	GO_RESPONSE_TO_ISOQUINOLINE_ALKALOID	0.253312480659563	0.865755643260275	0.669629656670378	0.899789790160676	29	DRD2,OPRK1,TACR3,PPP5C,ADA,MTOR,GNAO1,NPFF,PRKCE
GO:0021872	forebrain generation of neurons	GO_FOREBRAIN_GENERATION_OF_NEURONS	0.219450597775612	0.887267003878524	0.671541256757954	0.900339662834312	62	SHANK3,NRP1,ATP7A,DRD2,OGDH,RAPGEF2,SLC4A10,FGFR1,ERBB4,PAX6,DLX2,FGF8,UQCRQ,PLXNA3,POU3F4,DCLK2,GATA2
GO:0043046	dna methylation involved in gamete generation	GO_DNA_METHYLATION_INVOLVED_IN_GAMETE_GENERATION	-0.274973325710909	-0.853916977384149	0.671665402535486	0.900339662834312	18	TDRD1,TDRD12,MOV10L1,PICK1
GO:1900077	negative regulation of cellular response to insulin stimulus	GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS	-0.242749716815723	-0.869512841940529	0.67222665248981	0.900339662834312	31	TRIM72,PTPN2,MZB1,SOCS1,MSTN,INPP5K,SOCS3,LMBRD1
GO:1902930	regulation of alcohol biosynthetic process	GO_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS	0.232817973681899	0.876422805906617	0.672417829806394	0.900339662834312	44	P2RY1,ADCYAP1R1,FGF1,REST,CYP27B1,DKK3,TNF,SOD1,PTAFR,NFKB1
NA	negative regulation of transcription factor import into nucleus	GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS	0.240527285923985	0.871204494643436	0.67250212719735	0.900339662834312	37	PYDC2,AKAP1,SUFU,GSK3B,MTOR,FAF1,MDFI,CD36,LITAF,NFKBIA
GO:0017157	regulation of exocytosis	GO_REGULATION_OF_EXOCYTOSIS	-0.184420538246609	-0.923833480942488	0.67287321037667	0.900339662834312	178	ATP13A2,CFTR,HAP1,SMPD3,SYT4,NLGN1,SYN1,RIMS4,RAB27B,SYTL1,SYT17,SDC1,FOXF1,TRIM9,IQCF1,SNCA,ANXA1,RAB3B,RPH3A,RAB3C,C2CD4D,STXBP3,SNF8,PCLO,SYT6,CDK5,VAMP8,CACNA1I,UNC13B,KCNB1,SYT5,STXBP1,STXBP5L,PDPK1,SPINK1,RALA
GO:0007498	mesoderm development	GO_MESODERM_DEVELOPMENT	-0.196274813922432	-0.909045773149212	0.672874823450554	0.900339662834312	107	RPL38,TBX6,ITGA3,OSR1,MEST,BMP4,WNT5A,T,FGFR2,FOXF1,CRB2,ACVR1,KLF4
GO:0007379	segment specification	GO_SEGMENT_SPECIFICATION	-0.282467268449278	-0.848743062172415	0.67309565556205	0.900339662834312	16	OSR1,COBL,IRX1,MAFB,IRX2
GO:0033135	regulation of peptidyl serine phosphorylation	GO_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION	0.201466172956943	0.902897109736252	0.673128914137093	0.900339662834312	110	PLCL1,AKT2,HRC,NSD1,PINK1,FNIP1,INPP5J,OSM,GSK3B,CSF3,DMD,UCN,LATS1,RAF1,TERF2IP,TNF,PARK7,VEGFA,BAG4,IL11,SMAD7,FNIP2,CNKSR3,IFNA21,PFN2,NTRK3,DDIT4,PAQR3,BAK1,GCG,IFNA4,SPRY2,STK4
GO:0009063	cellular amino acid catabolic process	GO_CELLULAR_AMINO_ACID_CATABOLIC_PROCESS	0.20424974397657	0.900461489161651	0.673304916561686	0.900339662834312	100	IVD,HIBCH,MCCC2,DDO,AMT,AUH,ALDH7A1,PPAT,OTC,DLD,THNSL2,OGDH,HAAO,ASRGL1,IDO1,ACAT1,GLUD1,GOT2,PRODH2,GOT1,BCKDK,HOGA1,GCDH,DBT,GLUD2,DLST,PIPOX,ACMSD,CTH,ACADSB,QDPR,CRYM,ARG1,NOS2,GAD2,DDAH1
GO:1904591	positive regulation of protein import	GO_POSITIVE_REGULATION_OF_PROTEIN_IMPORT	-0.198254888225415	-0.905968284641212	0.673346312740396	0.900339662834312	99	CCL19,ARHGEF5,IL18,TGFBR1,BMP4,SFRP2,TNFSF14,IPO5,XBP1,EDAR,SULF2,HDAC3,EGFR,LEP,DAB2,CDH1,NLRP12,TLR9,HSP90AA1,RHOA,TLR2,NODAL
GO:0048524	positive regulation of viral process	GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS	-0.204205181077646	-0.901047878096657	0.673680041008435	0.900339662834312	81	PPIB,TARBP2,POLR2H,SNW1,TRIM11,MDFIC,PC,PABPC1,POLR2K,TOP2A,TRIM38,PPIH,TMPRSS2,GTF2F1
GO:0003272	endocardial cushion formation	GO_ENDOCARDIAL_CUSHION_FORMATION	0.294448275138629	0.846087541926937	0.673785758099593	0.900339662834312	15	TBX20,ENG,FGF8,MSX1,HEYL,DCHS1,SNAI1,HEY1,NOTCH1
GO:1902117	positive regulation of organelle assembly	GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY	0.231739685499473	0.876526988644629	0.673958014786566	0.900339662834312	45	LRSAM1,BMP10,RAB3GAP1,PIP4K2C,PAN2,CNOT6L,PIP4K2B,EP300,TNF,CSF2,PLK4,MYLK3,HTT,PROX1,CNOT1,CAPG
GO:0001541	ovarian follicle development	GO_OVARIAN_FOLLICLE_DEVELOPMENT	0.222205265304261	0.882989812224207	0.674051084474886	0.900339662834312	57	CHAT,EIF2B5,DMC1,ESR1,LFNG,CTNNA1,SPO11,ESR2,PCYT1B,VEGFA,SOHLH1,SOD1,EIF2B4,CENPI
GO:2000178	negative regulation of neural precursor cell proliferation	GO_NEGATIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION	0.275225116332655	0.854327664564852	0.674352331606218	0.90036142540838	20	RAPGEF1,KDM2B,CTNNA1,LIMS2,CCR2,PAX6
GO:0045920	negative regulation of exocytosis	GO_NEGATIVE_REGULATION_OF_EXOCYTOSIS	0.263402541456825	0.858304548892829	0.674907179355218	0.90036142540838	24	IL1RAPL1,CEACAM1,ABR,REST,CD300A,CCR2
GO:0043902	positive regulation of multi organism process	GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS	0.195387388911482	0.909447093485894	0.675094880661213	0.90036142540838	141	SMARCB1,P2RY1,ADAR,LRSAM1,DDX3X,BAD,PDE5A,C1QBP,DRD4,VIP,VPS4A,P2RY2,RAD23A,SASH1,ADARB1,CFL1,VPS37B,IFIT1,EP300,POLR2I,CCR2,ANKRD17,CYBA,PLAU,PTAFR,ZP3,ZNF502,VAPB,HPN,GTF2F2,POLR2C,OSBP,TSG101,LARP1,STOM,DDX60,GLRA1,SIRT2,NOS2,CHMP4B,TAF11,POLR2G,OXT,CHMP4C,FAM170B,PUM1,CCNT1
GO:0035036	sperm egg recognition	GO_SPERM_EGG_RECOGNITION	0.233388529297521	0.874282880796428	0.675137325529041	0.90036142540838	43	CATSPERG,CATSPER2,ZP2,ZPBP,TCP1,UBAP2L,FETUB,CCT3,OVGP1,ZP3,CATSPER4,CCT7,CCT4,ZPBP2,ACR,PRSS37,GLIPR1L1,CCT8,KCNU1,POMZP3,HVCN1,CRISP1
GO:0007188	adenylate cyclase modulating g protein coupled receptor signaling pathway	GO_ADENYLATE_CYCLASE_MODULATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.19727715384781	0.905896361194749	0.675916044112415	0.900688386323232	128	P2RY1,GNAS,GNA12,OPRL1,ADRB1,RXFP2,DRD4,VIP,NPY1R,ADRB2,GNG2,DRD2,OPRK1,ADRA2C,GPR52,RAPGEF2,ADCY7,ADCY5,GNAT2,ADCY8,ADCY9,HTR1E,S1PR1,GABBR1,ADCY4,CHRM2,ADORA2B,GNAO1,GRM4,GALR1,PTH
GO:0071548	response to dexamethasone	GO_RESPONSE_TO_DEXAMETHASONE	-0.239250192660578	-0.870666284750484	0.675967377332565	0.900688386323232	33	ASS1,AQP1,ERRFI1,STAR,CPS1,MSTN,HMBS
GO:0014904	myotube cell development	GO_MYOTUBE_CELL_DEVELOPMENT	-0.258618915681113	-0.857793332072451	0.676185250219491	0.900688386323232	23	KIAA1161,RYR1,WNT10B,C16orf89,MYOD1,BEND2,GPX1,IGF1,ACTA1,CAV2,SMYD3,SKI,NFATC2
GO:0071806	protein transmembrane transport	GO_PROTEIN_TRANSMEMBRANE_TRANSPORT	-0.222896809861145	-0.880596562874007	0.676934517103069	0.900788540200237	47	AZGP1,PEX10,PEX5L,SEC61G,TIMM10,TIMM9
GO:0046677	response to antibiotic	GO_RESPONSE_TO_ANTIBIOTIC	0.232110476986512	0.873759496759413	0.676956325979289	0.900788540200237	44	UQCRFS1,CYP17A1,JAK2,ZC3H8,CIITA,EP300,CDKN1B,SCN3A,ETS1,SOD1,HYAL1,HYAL2,ENDOG,CYP1A1,MEF2C,ADRB3,PPP2CB,PPP1R15A,CASP9
GO:0051262	protein tetramerization	GO_PROTEIN_TETRAMERIZATION	-0.192853888964413	-0.910929379772974	0.677174150618064	0.900788540200237	121	TRPM3,SHMT1,ACADL,NLGN1,TRPV5,DPYS,S100A10,HLA-DRB5,HIST1H4C,RPS19,IMPDH2,ANXA2,EVL,CNGA4,CAT,TP73,FBP1,HIST1H4D,TRPM6,RYR3,HIST1H4E,HIST1H3C,USP16
GO:0032387	negative regulation of intracellular transport	GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT	0.197215061341612	0.904836125832267	0.677330895795247	0.900788540200237	127	PYDC2,LRRK2,CALM3,AKAP1,RANGAP1,SP100,SUFU,PKIA,GSK3B,SIAH3,SIRT4,CABP1,PLN,CD300A,PDE2A,DERL3,CALM1,MTOR,INSIG1,YOD1,EMD,PARK7,BAG4,FAF1,MDFI,CD36,TRDN,TPR,LITAF,NFKBIA,FAM89B
GO:1902259	regulation of delayed rectifier potassium channel activity	GO_REGULATION_OF_DELAYED_RECTIFIER_POTASSIUM_CHANNEL_ACTIVITY	0.285043174693561	0.846781084333903	0.677726528790359	0.900958726662064	17	RNF207,VAMP2,AKAP6,KCNRG,ANK3,SUMO1
GO:0042168	heme metabolic process	GO_HEME_METABOLIC_PROCESS	0.25615846088702	0.859799011140476	0.678112924198304	0.901116503297075	27	COX15,ATPIF1,COX10,ALAD,FXN,HMOX2,NFE2L1,SLC25A38,FECH,SLC25A39
GO:2000117	negative regulation of cysteine type endopeptidase activity	GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY	-0.202489781159477	-0.899461380338204	0.679477002101331	0.902572844938074	84	SFN,AQP1,SFRP2,TNFSF14,WNT9A,SNCA,KLF4,NLE1,PLAUR,MAGEA3,SH3RF1,RAG1,HGF,RPS6KA1,FABP1,THBS1,TRIAP1,MDM2,IFI16,IFI6
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS	-0.241442820179393	-0.864831627794188	0.680577706893496	0.903401266566918	31	SFRP2,RIPK1,TRADD,BMP5,DAPK1,FAS,HGF,HMGB2
GO:0061025	membrane fusion	GO_MEMBRANE_FUSION	0.195780310091977	0.90574201271553	0.680649961110548	0.903401266566918	135	C2CD4A,DYSF,SYT9,VCPIP1,TIE1,MFN2,USP30,SYT8,VPS4A,SYTL2,VAMP2,MFN1,STX1A,SYT7,VPS11,VTI1A,BET1L,VPS39,STX4,SEC22C,SYT12,SYTL3,PLD6,VAMP1,RPH3AL,GOSR1,TMEM8C,TMEM175,HYAL2,C2CD4B,OPA1,UVRAG,UBXN2B,BAK1,STX10,DOC2B,LRMP,SYTL4
GO:0036473	cell death in response to oxidative stress	GO_CELL_DEATH_IN_RESPONSE_TO_OXIDATIVE_STRESS	-0.27648165208583	-0.84556500538456	0.680905826880651	0.903401266566918	17	MELK,ARL6IP5,BCL2,PDCD10,STK24,CYP1B1,MAP3K5,GPX1
GO:0032755	positive regulation of interleukin 6 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION	-0.211110265693411	-0.889467482397302	0.681852730497271	0.904125175257206	64	MAPK13,WNT5A,TBC1D23,XBP1,PYCARD,RIPK2,IL36B,IL17RC,TNFSF9,LILRB2,IL17F,TLR9,ADCYAP1,NOD1,F2R,TLR2
GO:0070509	calcium ion import	GO_CALCIUM_ION_IMPORT	-0.212988510321739	-0.886496290322516	0.681988657153311	0.904125175257206	60	BBC3,CCL3,CCL19,RYR1,CCL21,CDK5,CACNA1I,ORAI1,RYR3,ITPR3,SLC8A3,F2R,RASA3,CASK,PKD2,PAWR,TRPA1,FGF2,HTR2A
GO:0090026	positive regulation of monocyte chemotaxis	GO_POSITIVE_REGULATION_OF_MONOCYTE_CHEMOTAXIS	0.292329403243601	0.839999032451111	0.682856558672094	0.904446470874492	15	CCR2,S100A7,HMGB1,PLA2G7,CXCL12,CCL5,CCR1,CXCL10,TNFSF18
GO:0071230	cellular response to amino acid stimulus	GO_CELLULAR_RESPONSE_TO_AMINO_ACID_STIMULUS	-0.221081739666805	-0.877632164783864	0.683028473598847	0.904446470874492	48	ASS1,CEBPB,SOCS1,IPO5,XBP1,EGFR,RAPGEF3,FAS,CAPN2,RRAGC,CPEB4,PDGFD
GO:0045123	cellular extravasation	GO_CELLULAR_EXTRAVASATION	0.270146445969995	0.850254940215465	0.683037114962257	0.904446470874492	21	MADCAM1,CX3CL1,TNF,SELP,ITGB2,SELE,GOLPH3,PIK3CG
GO:0006901	vesicle coating	GO_VESICLE_COATING	-0.208093152061835	-0.89028565190473	0.683537276491407	0.904541266337454	69	TMED10,AREG,SNAP91,SCFD1,TMED2,ANKRD28,SEC24D,CALY,SEC24A,SEC13,COL7A1,F5,SEC31A,TMED9,CNIH2,LMAN1,MCFD2,NSF,PICALM
GO:0009648	photoperiodism	GO_PHOTOPERIODISM	0.269974034428453	0.849712294672158	0.683646162080357	0.904541266337454	21	NR2F6,DRD4,USP2,PPP1CB,MTA1,PER1,PPP1CC,CRY2
GO:0048806	genitalia development	GO_GENITALIA_DEVELOPMENT	-0.227772255529516	-0.872459384861824	0.68410913489539	0.904798172124905	41	RBP4,TYRO3,WT1,WNT5A,CTNNB1,BMP5
GO:0019229	regulation of vasoconstriction	GO_REGULATION_OF_VASOCONSTRICTION	0.21634796824262	0.880599456206222	0.685535035786869	0.904965777960103	64	AGT,TRPM4,NPY1R,HRH2,ATP1A2,ADRA2C,GJA1,DOCK4,CX3CL1,GJA5,KCNA5,ACE2
GO:0070849	response to epidermal growth factor	GO_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR	0.254671320079554	0.854807404807201	0.68567661117521	0.904965777960103	27	STAT5B,MCM7,MAPK1,BAG4,SOX9,PLCG1,TPR,CAD,MED1,ASCL1
GO:0048339	paraxial mesoderm development	GO_PARAXIAL_MESODERM_DEVELOPMENT	0.28765588973493	0.840511819171497	0.685679769538147	0.904965777960103	16	YAP1,FGFR1,DLL3,WNT11,SMAD3,FOXC2
GO:0042403	thyroid hormone metabolic process	GO_THYROID_HORMONE_METABOLIC_PROCESS	-0.284527203131449	-0.838207816446691	0.685691405320001	0.904965777960103	15	DUOX2,TG
GO:0090101	negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	-0.198036750361584	-0.899844234633085	0.6858179403884	0.904965777960103	96	VASN,TGFBR1,WNT5A,SFRP2,HTRA1,SNX25,SKIL,CIDEA,ACVR1,TOB1,UBA52,SMAD2,NOV,SMURF2,MAGI2,ONECUT1,CTDSPL2,PDPK1,UBB,PMEPA1,ABL1,SIRT1,EID2,TRIM33,CHRDL1
GO:0090288	negative regulation of cellular response to growth factor stimulus	GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	-0.193330618268971	-0.904961660497052	0.68589805357487	0.904965777960103	114	VASN,SULF1,TGFBR1,WNT5A,SFRP2,HTRA1,GATA3,SNX25,SKIL,CIDEA,SULF2,TOB1,PRDM14,UBA52,SMAD2,SMURF2,ONECUT1,DCN,CTDSPL2,THBS1,PDPK1,CASK,UBB,PMEPA1,ABL1,SIRT1,EID2,TRIM33,CHRDL1
GO:1901532	regulation of hematopoietic progenitor cell differentiation	GO_REGULATION_OF_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION	-0.237633385365789	-0.864782487605507	0.686272771597004	0.904965777960103	33	KDM1A,HIST1H4C,HIST1H4D,SCIN,ZBTB1,HIST1H4E,HMGB2,NFE2L2,TESC,PF4
GO:0002200	somatic diversification of immune receptors	GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS	0.236275321590735	0.865780552964515	0.686632446500868	0.904965777960103	39	ADAR,UNG,HSPD1,ERCC1,LIG3,CTNNBL1,AICDA,EXOSC3,PMS2P5,HMGB1,PRKDC,RNF168
GO:0044060	regulation of endocrine process	GO_REGULATION_OF_ENDOCRINE_PROCESS	0.229890397664271	0.869532283815226	0.686837797485204	0.904965777960103	45	AGT,GNAS,OPRK1,NKX3-1,UCN,AGTR2,GJA5,GDF9,CRHBP,GALR1
GO:0008610	lipid biosynthetic process	GO_LIPID_BIOSYNTHETIC_PROCESS	0.174278321102505	0.937737249024726	0.686924409592414	0.904965777960103	496	PIK3C2B,IDI2,CNBP,CHAT,LSS,PIK3R1,MTMR1,PPARD,LPIN1,HSD17B8,DDHD2,MOGAT1,PCYT1A,AGK,CERS4,SLC27A5,NDUFAB1,FITM2,PPM1L,TAZ,HSD11B2,CHPT1,FADS1,PLD1,ST6GALNAC4,ST8SIA6,CYP17A1,LIPT2,PRKAB2,THNSL2,LCAT,PLA2G5,QKI,SERINC5,INPP5J,PIP5K1B,ARF1,HMGCR,INPPL1,PLCE1,ST3GAL6,LPCAT4,AGPAT3,MTMR4,FGF1,PIK3R3,PI4KB,PTEN,MVD,LIAS,CYP27B1,CYP51A1,PRKAA2,INPP5D,ACER2,PIK3C3,ST3GAL3,CYB5R1,CYP7B1,FITM1,PIP4K2C,CLN8,IRS1,ST3GAL2,GGPS1,MGLL,PIKFYVE,SMPD4,MSMO1,PI4K2A,SPTSSB,GPAA1,ELOVL6,PIP4K2B,FGFR1,AGPAT1,PTGDS,CDS2,ST6GALNAC3,MBOAT2,INSIG1,CERS6,PCYT1B,HMGCS2,PIK3R5,PEX7,GGT7,PIK3C2G,ACOT8,DGKE,HMGCS1,MPPE1,P2RX7,PRPF19,GBGT1,PLD6,SQLE,FDX1,PIGM,SGPP1,LCLAT1,CYP3A4,IDI1,ACACB,PIP5K1C,GAB1,SGMS1,FGF6,VAPB,VAC14,FDFT1,MECR,PRKAG3,FGF8,MTMR14,SLC27A1,SACM1L,MED1,CYP1A1,INPP5F,CHKA,TAMM41,MBOAT1,PLP1,DPM2,SCP2,PLA2G4D,PIGS,NSDHL,ADM,PRKAG1,APOA5,MTMR2,COQ2,HSD17B3,PCYT2,ST3GAL4,PIK3R6,CDIPT,ISYNA1,PIK3R2,PIK3CB
GO:0031330	negative regulation of cellular catabolic process	GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS	0.194892616953038	0.902541584082718	0.687616214206025	0.905522760961455	136	HERC1,UBQLN4,SNRNP70,CSNK2A1,PPARA,LRRK2,APOC3,TSC1,N4BP1,MAD2L1,GOLGA2,PINK1,HDAC4,SUFU,CDK5RAP3,EGLN1,TLK2,SHH,RASIP1,MTOR,OPHN1,PARK7,TIMP3,APC,NPC1,PBK,KIF25,BAG6,ACACB,USP14,KLHL22,TPR,MAD1L1,UBXN1,DDIT4,CBFA2T3,MTMR2,MT3,WDR6,SIRT2,PIK3CG,CHMP4B,PLK1,PPARGC1A,GPLD1,DHX34,USP44,HSP90AB1
GO:0006271	dna strand elongation involved in dna replication	GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION	0.260757974467087	0.849687153386355	0.688269676138661	0.905801723944078	24	POLA2,LIG3,POLD2,GINS3,RFC3,GINS1,PRIM1,PARP2,PARP3
GO:0051781	positive regulation of cell division	GO_POSITIVE_REGULATION_OF_CELL_DIVISION	-0.192545974109389	-0.90391313077222	0.689168315875851	0.905801723944078	116	MRGPRX2,EPGN,WNT5A,FGF7,NEUROG1,RXFP3,DMRT1,FGFR2,ITGB1BP1,CSPP1,CAT,SH2B1,MSX2,OPN1LW,FGF4,OR1A2,FBXO5,FGF9,AURKB,NPM2,AURKC,RHOA,EDN1,PDGFD,CDC42,THBS4,CDC6,SPAST
GO:2000241	regulation of reproductive process	GO_REGULATION_OF_REPRODUCTIVE_PROCESS	-0.191388695173233	-0.907431512237549	0.689411993580079	0.905801723944078	124	TIMP1,CNR1,SULF1,WT1,BMP4,WNT5A,NUPR1,RETN,DMRT1,FGFR2,IQCF1,CALR,SEMA3A,XBP1,CTNNB1,ACVR1C,MSX2,STK3,FBXO5,SMURF2,EDNRB,ASTL,CDC20,SPINK1,NPM2,ACVR1B,NODAL,GPR149,PTGER4,MOS,PLB1,INHBA,NANOS2
GO:0042770	signal transduction in response to dna damage	GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE	0.205931741784611	0.889951659145576	0.689893348643805	0.905801723944078	89	PPP2R5C,NPM1,HIPK2,SP100,PLAGL1,TFDP2,CNOT6L,SMC1A,CNOT4,EP300,CDKN1B,RPS6KA6,CDK1,PRPF19,GADD45A,CDC25C,CNOT8,ARID3A,ATRX,BID,PRKDC,CNOT1,BRCA2,PAXIP1,USP10,CASP2,RBL2,GRB2,MDM4
GO:0035902	response to immobilization stress	GO_RESPONSE_TO_IMMOBILIZATION_STRESS	-0.261789505344733	-0.847534370044573	0.690084899277592	0.905801723944078	21	TPH1,PPARG,KEAP1,CYP1A2,HNMT,GAL,PTGER4,PTPN5,PTK2B,FOS
GO:0032890	regulation of organic acid transport	GO_REGULATION_OF_ORGANIC_ACID_TRANSPORT	0.226756304141762	0.869571021836469	0.690235569142241	0.905801723944078	48	AKT2,P2RY2,ATP1A2,SLC6A1,RAB3GAP1,AGTR2,GABBR1,NPY5R,NCOR1,P2RX7,SLC38A3
GO:1902806	regulation of cell cycle g1 s phase transition	GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION	0.194335008393737	0.902602789063614	0.69041665258676	0.905801723944078	139	CUL4A,PPP2R5C,DDX3X,FBXW7,NPM1,CREBBP,CCND1,C8orf4,PLAGL1,KANK2,ZNF655,PTEN,TFDP2,CNOT6L,EZH2,CNOT4,FAM83D,DGKZ,EP300,FBXO31,MYO16,KCNA5,ANKRD17,CDKN1B,CDK1,GADD45A,CDC25C,CNOT8,ARID3A,RDX,GIGYF2,BID,PRKDC,CTDSP2,CNOT1,CYP1A1
GO:1900744	regulation of p38mapk cascade	GO_REGULATION_OF_P38MAPK_CASCADE	0.257889696806937	0.849050948113379	0.691490337853958	0.905801723944078	25	SASH1,OPRK1,CAV3,MAP3K4,ULK4,VEGFA,GADD45A,XDH,HSPH1,PER1
GO:0015858	nucleoside transport	GO_NUCLEOSIDE_TRANSPORT	0.286425502957335	0.836916708952569	0.691627172195893	0.905801723944078	16	SLC25A17,SLC29A2,GJA1
GO:0038095	fc epsilon receptor signaling pathway	GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY	0.196910615198932	0.898386891856313	0.691696308524942	0.905801723944078	123	PIK3R1,PSMD11,CALM3,PSMD2,UBE2N,PSMC6,BTRC,PSMC5,PSMB7,PSME4,LAT2,CALM1,PPP3R1,IKBKB,PSMA8,MAPK1,PSMD8,PSMB10,MALT1,PLCG1,PSMD3,PSMB1,NFKB1,BTK,PSMA5,PSMB9,MAPK8,NFKBIA,TEC,PRKCQ,PSMD6,PSMB3,PIK3R2,PIK3CB,PSMB6,PSMD1,NFATC1,MAP2K7,GRB2
GO:0045606	positive regulation of epidermal cell differentiation	GO_POSITIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION	0.277865427549353	0.838317669277407	0.692073453775739	0.905801723944078	18	TRIM16,CYP27B1,PRKCH,PTCH1,NCOA3,PTCH2,MED1
GO:0050871	positive regulation of b cell activation	GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION	-0.204501323897555	-0.889252014643219	0.692182788216191	0.905801723944078	75	TCF3,CLCF1,XBP1,BST1,CDKN1A,SLC39A10,IGHG4,CHRNB2,IGHG2,IGHG1,WHSC1,ATP11C,IGHD,IL5,IGKC,IGLL1,MIF,IGLC1,MMP14,BCL2,CD81,ZAP70,PRDM1,TNFRSF13C
GO:0032652	regulation of interleukin 1 production	GO_REGULATION_OF_INTERLEUKIN_1_PRODUCTION	-0.215200195173402	-0.879296270343941	0.692234202265593	0.905801723944078	55	CCL3,GSDMD,CCL19,WNT5A,ANXA1,ERRFI1,PYCARD,SAA1,NLRP3,NLRP12,IFNAR1,NOD1,F2R,PTGER4,IFI16
GO:0071772	response to bmp	GO_RESPONSE_TO_BMP	-0.198863273247583	-0.895411319000288	0.692240586612595	0.905801723944078	91	ZCCHC12,SPINT1,BMP4,BMP2,T,GATA3,GDF10,ACVR1,BMPR1B,GATA5,TNMD,MSX2,BMP5
GO:0070098	chemokine mediated signaling pathway	GO_CHEMOKINE_MEDIATED_SIGNALING_PATHWAY	0.217967091281073	0.875027143884141	0.692628922770729	0.905801723944078	60	CCL1,XCL1,CCL24,CXCL11,GPR17,CXCR3,CXCL2,CX3CL1,CCR2,CCL16,CXCL9,CCR8,CXCL3,CCL23
GO:0046471	phosphatidylglycerol metabolic process	GO_PHOSPHATIDYLGLYCEROL_METABOLIC_PROCESS	0.247358707522368	0.852516483614162	0.692701968152053	0.905801723944078	30	TAZ,PLA2G5,LPCAT4,CDS2,HADHB,PLD6,LCLAT1,HADHA,SLC27A1,TAMM41,PLA2G4D
GO:0030490	maturation of ssu rrna	GO_MATURATION_OF_SSU_RRNA	-0.230278136229436	-0.866183122332323	0.692762450734504	0.905801723944078	38	RPS19,WDR46,RPS8,NOC4L,RPS24,RPS16,KRR1
GO:0002262	myeloid cell homeostasis	GO_MYELOID_CELL_HOMEOSTASIS	0.208228795344356	0.885057036182582	0.692908695956836	0.905801723944078	81	ADAR,EPAS1,ATPIF1,ACIN1,HIPK2,ADD1,RHAG,JAK2,NCSTN,FLVCR1,RPS14,VEGFA,SOD1,SPI1,HMGB1,JMJD6,BCL6,HOXB6,ITPKB,MED1,AXL,BAK1,SRF,GPI,NFE2L1,TGFBR3
GO:1903053	regulation of extracellular matrix organization	GO_REGULATION_OF_EXTRACELLULAR_MATRIX_ORGANIZATION	0.262137028370842	0.845194963182614	0.693747474376401	0.905801723944078	23	AGT,CLASP1,CHADL,PARK7,ETS1,SOX9,SMAD3,DDR2,CLASP2
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	GO_POSITIVE_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	0.285927578112749	0.835461804909688	0.693783105659325	0.905801723944078	16	FLT1,GRB10,ITGB3,VEGFB
GO:0046320	regulation of fatty acid oxidation	GO_REGULATION_OF_FATTY_ACID_OXIDATION	0.253155290663478	0.849718833505328	0.693826346537736	0.905801723944078	27	AKT2,PPARA,LONP2,SIRT4,IRS1,MTOR,FABP3,ACACB,ACADVL
GO:0034101	erythrocyte homeostasis	GO_ERYTHROCYTE_HOMEOSTASIS	0.213878866167166	0.878731301876409	0.694111846738977	0.905801723944078	67	ADAR,EPAS1,ATPIF1,ACIN1,HIPK2,ADD1,RHAG,JAK2,FLVCR1,RPS14,VEGFA,SPI1,JMJD6,BCL6,HOXB6,MED1,AXL,SRF,GPI,NFE2L1,TGFBR3
GO:2000300	regulation of synaptic vesicle exocytosis	GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS	-0.270168274930228	-0.838995113860811	0.6944414346083	0.905801723944078	18	NLGN1,SYN1,RIMS4
GO:0072132	mesenchyme morphogenesis	GO_MESENCHYME_MORPHOGENESIS	-0.230734211985485	-0.862993893800131	0.694493465877359	0.905801723944078	37	OSR1,WNT5A,BMP2,FOXF1,MSX2,SMAD2
GO:0051000	positive regulation of nitric oxide synthase activity	GO_POSITIVE_REGULATION_OF_NITRIC_OXIDE_SYNTHASE_ACTIVITY	0.274229716754196	0.839175102660575	0.694555629679045	0.905801723944078	19	CALM3,ESR1,AGTR2,CALM1
GO:0051931	regulation of sensory perception	GO_REGULATION_OF_SENSORY_PERCEPTION	0.242793797438019	0.855943978789241	0.694879737609329	0.905822881389873	33	OPRL1,VIP,ADRB2,OPRK1,ADRA2C,MGLL,FGFR1,MTOR,PTAFR,FAM19A4,NPFF
GO:2000641	regulation of early endosome to late endosome transport	GO_REGULATION_OF_EARLY_ENDOSOME_TO_LATE_ENDOSOME_TRANSPORT	-0.277673282677055	-0.8343383412762	0.695110072082603	0.905822881389873	16	EZR,MAP2K2,DAB2,MSN
GO:0001893	maternal placenta development	GO_MATERNAL_PLACENTA_DEVELOPMENT	0.246816811723768	0.850648851359225	0.695894059062802	0.906399418582952	30	PPARD,ESR1,GHSR,CYP27B1,STC2,RXRA,DEDD,PRDX3,NR2F2
GO:0032271	regulation of protein polymerization	GO_REGULATION_OF_PROTEIN_POLYMERIZATION	0.191122383737006	0.90501980067839	0.696399892933619	0.906399418582952	159	SPTB,TUBGCP5,CLASP1,TBCD,CLIP1,TUBGCP2,CCL24,LMOD1,LMOD3,PINK1,INPP5J,ARF1,ADD1,CAV3,SPIRE1,CSF3,VDAC2,ACTR3B,FAM21C,PPP1R9A,LATS1,CAPZB,WASL,TMOD1,MTOR,CDKN1B,BAG4,ARFGEF1,JMY,FHOD3,TUBGCP6,RDX,C15orf62,MKKS,KANK1,MLST8,PRKCE,TUBGCP3,PFN2,ARF6
GO:0009064	glutamine family amino acid metabolic process	GO_GLUTAMINE_FAMILY_AMINO_ACID_METABOLIC_PROCESS	-0.212052549687176	-0.879256010013853	0.696579440105951	0.906399418582952	59	ASS1,GFPT2,TAT,PYCR1,CPS1,UROC1,AMDHD1,GGT1,FTCD,DDAH2,OAT,FAH,LGSN,PYCR2,NOXRED1
NA	negative regulation of receptor activity	GO_NEGATIVE_REGULATION_OF_RECEPTOR_ACTIVITY	0.25260615449682	0.847875651236667	0.696774902477886	0.906399418582952	27	CALM3,PCSK9,ZGPAT,CALM1,SOCS4,LYNX1,CRHBP,TRDN,CASQ2,PPARGC1A,HEYL,GSTO1
GO:0043489	rna stabilization	GO_RNA_STABILIZATION	0.248501372118326	0.849312535683938	0.696898899373939	0.906399418582952	29	MAPKAPK2,VIP,THRAP3,MTOR,YBX1,APOBEC1
GO:2000772	regulation of cellular senescence	GO_REGULATION_OF_CELLULAR_SENESCENCE	0.256490638204518	0.844444823682829	0.698574076452992	0.908010422226551	25	HMGA1,PRKDC,BCL6,TWIST1,NUAK1,CDKN2A,PNPT1,CDK6,YPEL3,BCL2L12,ING2,TERT,ZKSCAN3
GO:0006541	glutamine metabolic process	GO_GLUTAMINE_METABOLIC_PROCESS	0.266894830958298	0.840020855078987	0.698798516139749	0.908010422226551	21	PPAT,SIRT4,GLUD1,ADSSL1,ASNS,CAD,NIT2
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	0.222130857132387	0.866624069511515	0.699006355742548	0.908010422226551	52	CRIPAK,DDX17,RNF14,KANK2,CYP7B1,PPP5C,ZNF366,EP300,TCF21,PARK7,HDAC6
GO:0050866	negative regulation of cell activation	GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION	0.192731961042161	0.901275751915911	0.699413094073599	0.908010422226551	146	CTLA4,PDE5A,PDGFB,SCGB1A1,ADRB2,HLX,XCL1,LGALS3,SPN,CEACAM1,ABR,ZC3H8,PELI1,INPP5D,PRKAR1A,CD300A,IDO1,LAX1,SHH,IRF1,DTX1,CCR2,IL4,MICA,SLA2,PKN1,RHBDD3,DUSP3,IL2,HMGB1,PAG1,GNRH1,MAD1L1,LILRB1,BCL6,TNFRSF14,PRKG1,FOXJ1,TNFSF4,AXL,TSPAN32
GO:0044783	g1 dna damage checkpoint	GO_G1_DNA_DAMAGE_CHECKPOINT	0.21273919122431	0.876327710042812	0.700216583613601	0.908010422226551	68	PPP2R5C,NPM1,CCND1,PLAGL1,TFDP2,CNOT6L,CNOT4,DGKZ,EP300,FBXO31,CDKN1B,CDK1,GADD45A,CDC25C,CNOT8,ARID3A,GIGYF2,PRKDC
GO:0045730	respiratory burst	GO_RESPIRATORY_BURST	-0.281107571511695	-0.82813369375649	0.700473995195117	0.908010422226551	15	CD55
GO:0007007	inner mitochondrial membrane organization	GO_INNER_MITOCHONDRIAL_MEMBRANE_ORGANIZATION	0.284602929960789	0.831591269079562	0.7005111049159	0.908010422226551	16	LETM1,TAZ,TIMM22,NDUFA13,OPA1,CHCHD3,IMMT,APOO,AFG3L2,OMA1,SAMM50,C19orf70
GO:0050709	negative regulation of protein secretion	GO_NEGATIVE_REGULATION_OF_PROTEIN_SECRETION	-0.19550317778005	-0.894932530012604	0.700558792058019	0.908010422226551	100	APOA2,EZR,TNFRSF21,ANXA4,ANGPT1,RHBDF1,ANXA5,CIDEA,OPRM1,ANXA1,DPH3,ACVR1C,NOV,NR1H3,KCNB1,NLRP3,NLRP12,CD34,STXBP5L
GO:0035809	regulation of urine volume	GO_REGULATION_OF_URINE_VOLUME	0.272943947625233	0.835240498294696	0.700744941071826	0.908010422226551	19	OPRL1,ADRB2,DRD2
GO:0033238	regulation of cellular amine metabolic process	GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS	0.206737059229871	0.882534023593601	0.70083513872388	0.908010422226551	83	DRD4,PSMD11,PSMD2,PSMC6,LDLR,TACR3,SIRT4,PSMC5,PSMB7,PSME4,PSMA8,PARK7,PSMD8,PSMB10,APC,PSMD3,MAOB,PSMB1,OAZ1,PSMA5,PSMB9,HPN,PSMD6,ACMSD,PSMB3,PSMB6,PSMD1
GO:1901099	negative regulation of signal transduction in absence of ligand	GO_NEGATIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND	0.245638671116039	0.846588415006836	0.7030078616639	0.909843192250062	30	EYA1,CTNNA1,STRADB,CX3CL1,TNF,CSF2
GO:0060142	regulation of syncytium formation by plasma membrane fusion	GO_REGULATION_OF_SYNCYTIUM_FORMATION_BY_PLASMA_MEMBRANE_FUSION	0.260212918034743	0.838991153004457	0.703133610080453	0.909843192250062	23	EHD1,CFLAR,IL4,SCGB3A1,CXCL9,GDF15,FLOT1
GO:0051258	protein polymerization	GO_PROTEIN_POLYMERIZATION	0.217627620464036	0.868042576162951	0.703248197917594	0.909843192250062	58	NDE1,TUBGCP5,CLASP1,MSRB2,TUBGCP2,GOLGA2,JAK2
GO:0016137	glycoside metabolic process	GO_GLYCOSIDE_METABOLIC_PROCESS	-0.280492198114933	-0.826320823895462	0.70333095253555	0.909843192250062	15	SLC34A1,AKR1C3
GO:0032527	protein exit from endoplasmic reticulum	GO_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM	-0.268005103872951	-0.832277485938104	0.703933253873659	0.910272505777463	18	AUP1,SURF4,HM13,TMED9,DERL2,LMAN1,FAF2,DERL1
GO:0060395	smad protein signal transduction	GO_SMAD_PROTEIN_SIGNAL_TRANSDUCTION	-0.21601430114703	-0.872085916195934	0.704464629533151	0.910529355839776	52	GDF5,BMP4,BMP2,T,GDF10,LEFTY1,MSTN,BMP5,SMAD2,MAGI2,NODAL,AFP,HNF4A,INHBA
GO:0070997	neuron death	GO_NEURON_DEATH	0.226301794297661	0.85986648592901	0.704672897196262	0.910529355839776	46	SIAH1,APP,DPYSL4,LRRK2,MAX,POU4F3,ATN1,CCR2,PLAU,FAM162A,ENDOG,BID
GO:0050860	negative regulation of t cell receptor signaling pathway	GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY	-0.275472489954054	-0.827725512946811	0.705586942875079	0.911360571649085	16	EZR,PTPN2
GO:0007610	behavior	GO_BEHAVIOR	0.173636097885263	0.93155909903322	0.707394860526155	0.913345262957821	480	P2RY1,CPEB3,SHANK3,CHAT,AGT,NLGN3,USP46,OPRL1,ATP7A,ITGA8,SCN1A,NRXN1,PREX2,DLG4,BBS12,STRN,SLC24A2,HDAC2,DRD4,VIP,NPY1R,PAFAH1B1,TRPV1,APP,DDO,ALS2,ADRB2,PPARA,NDRG4,LRRK2,VLDLR,TSC1,HRH2,SHANK1,HAND2,MUSK,ATP1A2,DRD2,OPRK1,HIPK2,GHSR,SLC6A1,RNF180,VPS13A,GLP1R,HMGCR,OSM,CHD7,GPR52,USP2,SNCG,RASGRF1,PTEN,UCN,CLN8,GRIA1,ADCY5,DACH1,IDO1,AGTR2,NPS,SLC4A10,GPRC5B,NPTX2,EP300,PRKCZ,TMOD1,PAIP2,FBXL20,ADCY8,ESR2,TRMT1L,MTOR,CREB1,NPY5R,ACE2,RGS14,PARK7,NPY,HOMER1,VDAC1,CACNA1B,SOD1,NPC1,CNTFR,EPHA4,TANC1,NMUR2,MKKS,CRHBP,NCOA1,FXN,GNAO1,HTT,SDK1,NPY6R,FGF12,BHLHB9,SLURP1,UBR3,ATP1A3,GIGYF2,EPM2A,AAAS,PRKCE,NTF4,NLGN4X,PCDH17,EIF4G1,MTA1,DNAJC9,HCRTR1,GJB4,NHLH2,HOXD10,NLGN2,MBD5,TH,FOSL1,NEGR1,MEF2C,SRF,GCG
GO:0045910	negative regulation of dna recombination	GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION	0.286443261387908	0.82308539527062	0.708321716017026	0.91397850341906	15	FBXO18,ZRANB3,TERF2IP,BCL6,MLH1,FOXP3
GO:0031589	cell substrate adhesion	GO_CELL_SUBSTRATE_ADHESION	-0.185462027656977	-0.906948866357361	0.708566200108809	0.91397850341906	151	VTN,MSLN,TYRO3,ITGA3,PIP5K1A,ITGB8,CTGF,NPNT,ANGPT1,THBS3,ADAM15,ITGB1BP1,TNXB,CTNNB1,PARVA,ANGPTL3,CCL21,HPSE,WHAMM,ANTXR1,RHOD,PARVG,CDK5
GO:0006694	steroid biosynthetic process	GO_STEROID_BIOSYNTHETIC_PROCESS	0.198646556164203	0.887390344664091	0.708760013036244	0.91397850341906	108	IDI2,CNBP,LSS,HSD17B8,SLC27A5,HSD11B2,CYP17A1,HMGCR,MVD,CYP27B1,CYP51A1,PRKAA2,CYB5R1,CYP7B1,GGPS1,MSMO1,INSIG1,HMGCS2,ACOT8,HMGCS1,SQLE,FDX1,CYP3A4,IDI1,FDFT1,MED1,SCP2,NSDHL,ADM,APOA5,HSD17B3
GO:0051302	regulation of cell division	GO_REGULATION_OF_CELL_DIVISION	-0.176195630357062	-0.922783335760717	0.709205785598663	0.91397850341906	248	MRGPRX2,TOM1L1,SFN,EPGN,BMP4,WNT5A,CUL7,SFRP2,FGF7,NEUROG1,RXFP3,DMRT1,FGFR2,ITGB1BP1,NEK2,CALR,PRMT5,CETN2,CSPP1,CCP110,CAT,SH2B1,SH3GLB1,PTTG3P,MSX2,OPN1LW,ANLN,ZFYVE19,FGF4,GIT1,CCNB1,OR1A2,FBXO5,FGF9,TEX14,CDC20,CHMP5,AURKB,LCMT1,NPM2,PSMG2,AURKC,WNT9B,RHOA,KNTC1,ZW10,MYC,EDN1,PDGFD,SUSD2,CDC42,MOS,THBS4,ANAPC4,NANOS2,GEN1,CDC6,SPAST
GO:0043506	regulation of jun kinase activity	GO_REGULATION_OF_JUN_KINASE_ACTIVITY	-0.202164454314151	-0.881171700684331	0.709407471117413	0.91397850341906	76	MAPK8IP1,TNFSF11,CCL19,ARHGEF5,WNT5A,SFRP2,MDFIC,TNXB,TP73,RIPK1,RPS3,ZNF675,TLR9,MAP3K11,EDN1,FCER1A,MAP3K2
GO:0009112	nucleobase metabolic process	GO_NUCLEOBASE_METABOLIC_PROCESS	-0.229388208079324	-0.85262826346197	0.709962787173831	0.91397850341906	36	SHMT1,AOX1,DPYS,GART,PAICS,CPS1,TYMS,GDA,ACPP,UCK1,CMPK1
GO:0060603	mammary gland duct morphogenesis	GO_MAMMARY_GLAND_DUCT_MORPHOGENESIS	-0.24149200596271	-0.843720517000852	0.710064655647991	0.91397850341906	28	AREG,WNT5A,FGFR2,CSF1,MSX2
GO:0021545	cranial nerve development	GO_CRANIAL_NERVE_DEVELOPMENT	-0.222903183871643	-0.858866808746633	0.710461414286355	0.91397850341906	42	SEMA3F,HOXA3,LPAR1,SEMA3A,CTNNB1
GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	GO_REGULATION_OF_PROTEIN_INSERTION_INTO_MITOCHONDRIAL_MEMBRANE_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	0.248133410619856	0.840782836791511	0.710597055865411	0.91397850341906	28	BAD,DYNLL2,GZMB,NMT1,PPP3R1,PPP1R13B,BID,MAPK8,YWHAG,TP53BP2,BMF
GO:0032651	regulation of interleukin 1 beta production	GO_REGULATION_OF_INTERLEUKIN_1_BETA_PRODUCTION	0.226371061521942	0.856220825727178	0.710600636793726	0.91397850341906	45	TRIM16,CARD8,PYDC2,GHSR,PANX1,JAK2,MEFV,CCR2,P2RX7,HSPB1,HMGB1,SMAD3
GO:0008347	glial cell migration	GO_GLIAL_CELL_MIGRATION	-0.233582473079113	-0.850040628001265	0.711338149904703	0.91415783280881	33	CCL3,TSPO,RTN4,CTNNB1,CDK5,SRGAP2,MMP14,VCAN,APCDD1,FN1,LAMB1,CCL2
GO:0032869	cellular response to insulin stimulus	GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS	-0.187492381816013	-0.901628165196741	0.711404796867352	0.91415783280881	135	ATP6V1C2,ALDOB,RAB31,ATP6V1B1,PTPN2,BAIAP2L2,PRKCI,PKLR,XBP1,ATP6V0D1,ATP6V1H,IGFBP1,ERRFI1,STAR,HIF1A,BAIAP2,RAB13,RAB10,ADIPOQ,RHOQ,PPARG,DENND4C,AP3S1,NAMPT
GO:0006220	pyrimidine nucleotide metabolic process	GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS	-0.226134803339859	-0.856260905757928	0.711554819358016	0.91415783280881	39	DTYMK,SHMT1,DUT,NME9,SMUG1,NEIL2,TYMS,NT5M,DCTD,UCK1,CMPK1
GO:2000279	negative regulation of dna biosynthetic process	GO_NEGATIVE_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	0.244130562730237	0.841390751779814	0.711982197252978	0.914357907651096	30	MCRS1,GJA1,OBFC1,DACH1,ACD
GO:2000779	regulation of double strand break repair	GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR	-0.236433445923409	-0.8468883926679	0.712652844231792	0.914664988071701	31	KDM1A,FOXM1,FIGNL1,KDM4D,RPA2,WHSC1,SIRT6,POLQ
NA	cell substrate adherens junction assembly	GO_CELL_SUBSTRATE_ADHERENS_JUNCTION_ASSEMBLY	0.258184496169423	0.832451016517701	0.713364681679586	0.914664988071701	23	TAOK2,TESK2,DLC1,PTPRK
GO:0051493	regulation of cytoskeleton organization	GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION	0.173709496713635	0.928526990004434	0.713643040763863	0.914664988071701	460	AMOT,SHANK3,CEP192,SPTB,MARK2,SPAG5,TUBGCP5,PIK3R1,WDR62,GPM6B,BIRC8,NPM1,MAP1A,SERPINF2,CLASP1,SSH2,TBCD,DLC1,PAFAH1B1,DIXDC1,CRIPAK,ROCK2,SBDS,TSC1,SHANK1,EPHA1,CLIP1,TUBGCP2,BMP10,ARHGEF2,ARAP1,CCL24,GOLGA2,LMOD1,LMOD3,INPP5J,ARF1,DYNC1H1,ADD1,CAV3,CHORDC1,SPIRE1,CSF3,ACTR3B,FAM21C,PPP1R9A,FZD10,GPSM2,EPHA3,AKAP13,LIMK1,SMC1A,CEP85,LATS1,EP300,MAP4,CAPZB,WASL,TMOD1,MTOR,KIFC1,DAPK3,S1PR1,SEMA5A,TEK,TUBG1,PLK4,CDKN1B,RGS14,NCOR1,MAPK1,HDAC6,PPFIA1,BAG4,ARFGEF1,JMY,APC,P2RX7,FHOD3,ARHGDIB,CCDC88A,MYLK3,SSH1,WNT11,TUBGCP6,RDX,C15orf62,MKKS,KANK1,SMAD3,MLST8,CFL2,GAS2L2,TPR,HAUS8,PRKCE,BCAS3,TUBGCP3,CKAP5,ODAM,PLXNA3,PFN2,ARF6,UVRAG,TMEFF2,PROX1,NTRK3,ESPL1,EPHA5,ABL2,CAPG,EML1,PRKCQ,NOX4,MEF2C,SYNPO
GO:0007044	cell substrate junction assembly	GO_CELL_SUBSTRATE_JUNCTION_ASSEMBLY	0.231977286582629	0.850031319820205	0.713707345286293	0.914664988071701	39	TAOK2,LAMC1,TESK2,DLC1,ITGB3,PTPRK,DST
GO:0046688	response to copper ion	GO_RESPONSE_TO_COPPER_ION	0.251267310049402	0.835517557824562	0.713746126624984	0.914664988071701	26	TK1,ATP7A,LCAT,ATP5D,PARK7,CDK1,SOD1,NFKB1,S100A13
GO:0010922	positive regulation of phosphatase activity	GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY	0.251183230204615	0.835237974354013	0.714204514200847	0.914664988071701	26	CALM3,AKAP6,JAK2,CD300A,AGTR2,CALM1,PPP1R12A,SMAD3,MEF2C,GPLD1,PPP1R15A
GO:0045839	negative regulation of mitotic nuclear division	GO_NEGATIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION	0.242122479782265	0.841176376432508	0.71428050603376	0.914664988071701	31	AURKAIP1,CSNK2A1,MAD2L1,NME6,APC,ATRX,KLHL22,TPR,MAD1L1,TOM1L2
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY	-0.218740680302218	-0.860147127446511	0.714395203101754	0.914664988071701	46	BBC3,PTPN2,SKIL,DFNA5,BCAP31,RIPK3,PRKRA,RPS3,S100A9
NA	regulation of neurological system process	GO_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS	-0.208715008230815	-0.871262947552413	0.715574015007228	0.915462234325368	61	CCL3,TNFRSF21,NPY2R,OPRM1,GRIN2A,EIF2AK3,MAG,NOV,EDNRB,OPRD1,HGF,GRIN2D,F2R,CARTPT,HCRT,EDN1,ACPP,PAWR,IL10,NRG1
GO:1901862	negative regulation of muscle tissue development	GO_NEGATIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	0.237959920816101	0.844766598265236	0.71587601862631	0.915462234325368	34	PRICKLE1,CAPN3,GJA1,USP2,CAV3,TGFBR2,SHH,LUC7L,TBX5,FGF8,TWIST1,IGFBP5,MYOCD,SIRT2,DKK1,USP19,SIX4
GO:0072148	epithelial cell fate commitment	GO_EPITHELIAL_CELL_FATE_COMMITMENT	-0.277519900349142	-0.817564532079871	0.716143973335065	0.915462234325368	15	RARA,ACVR1
GO:0021696	cerebellar cortex morphogenesis	GO_CEREBELLAR_CORTEX_MORPHOGENESIS	0.245285110636621	0.838320197206434	0.716173544819026	0.915462234325368	29	HERC1,ATP7A,NRXN1,GLI2,CBLN1,LDB1,LHX1,PROX1,TRNP1,SMO,AGTPBP1
GO:0031103	axon regeneration	GO_AXON_REGENERATION	0.260314718398199	0.82916078706225	0.716576752407431	0.915462234325368	22	MTR,LAMB2,CTNNA1,JAK2,RXRA
GO:0050994	regulation of lipid catabolic process	GO_REGULATION_OF_LIPID_CATABOLIC_PROCESS	-0.217866781264198	-0.860724470956727	0.716819144621209	0.915462234325368	47	APOA2,CNR1,APOC1,LGALS12,CIDEA,AADAC,ANGPTL3,HCAR2,RARRES2,FABP1
GO:0006284	base excision repair	GO_BASE_EXCISION_REPAIR	-0.22730957176024	-0.850185027800514	0.716921702222719	0.915462234325368	37	MPG,RPA3,XRCC1,SMUG1,NEIL2,RPA2,SIRT6,POLQ
GO:1901292	nucleoside phosphate catabolic process	GO_NUCLEOSIDE_PHOSPHATE_CATABOLIC_PROCESS	-0.206483416884884	-0.872458236858458	0.717926206593813	0.916397273945686	65	MPG,NUDT18,DUT,ENTPD2,SMPDL3A,NUDT5,CAT,PDE11A,SMUG1,NEIL2
GO:0034114	regulation of heterotypic cell cell adhesion	GO_REGULATION_OF_HETEROTYPIC_CELL_CELL_ADHESION	-0.265127910513467	-0.823342494696578	0.718474374255066	0.916558628565544	18	ALOX15,KLF4,ADIPOQ
GO:0021511	spinal cord patterning	GO_SPINAL_CORD_PATTERNING	0.254904083621677	0.830612086329109	0.718597213542624	0.916558628565544	24	GLI2,SUFU,SHH,DLL4,GDF11,PAX6,NKX2-2,ASCL1,SMO,LHX3
GO:0090175	regulation of establishment of planar polarity	GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY	0.198569778133539	0.881378554053392	0.718991179713341	0.916707118448606	104	PRICKLE1,DVL2,PSMD11,TIAM1,PSMD2,PSMC6,PRICKLE2,PSMC5,PSMB7,MED12,PSME4,ANKRD6,ZNRF3,PSMA8,FZD6,PSMD8,AP2M1,PSMB10,WNT11,PSMD3,PSMB1,PSMA5,MLLT3,PSMB9,CELSR2,PSMD6,PSMB3,PSMB6,PSMD1,SEC24B
GO:0048017	inositol lipid mediated signaling	GO_INOSITOL_LIPID_MEDIATED_SIGNALING	0.196379957781091	0.883591563102015	0.719669636292129	0.916707118448606	113	PIK3C2B,PIK3R1,PDGFB,PREX2,C1QBP,TNRC6C,PLD1,PLCH1,TNRC6A,FGF1,PI4KB,PTEN,PIK3C3,IRS1,CA8,FGFR1,ERBB4,TNRC6B,MTOR,PIK3R5,PIK3C2G,MOV10,PTAFR,ZP3,CD80,GAB1,FGF6,MLST8,MAPKAP1,FGF8,EGF,INPP5F,PIK3R2,PIK3CB,EREG,GRB2,SIRT2,PIK3CG,RPS6KB1,PIK3C2A,NF1,NGF
GO:0010832	negative regulation of myotube differentiation	GO_NEGATIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION	-0.268177851835532	-0.82016945797523	0.719816585197041	0.916707118448606	17	TRIM72,XBP1,HDAC3,NOV,BHLHA15,CEACAM5
GO:1902742	apoptotic process involved in development	GO_APOPTOTIC_PROCESS_INVOLVED_IN_DEVELOPMENT	-0.261828445602407	-0.824642838131769	0.720144228680655	0.916707118448606	19	CYR61,SLIT3,ROBO2,FGF4,BAX
NA	er to golgi vesicle mediated transport	GO_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT	-0.184424782330125	-0.902554469695044	0.720337933255704	0.916707118448606	152	CD55,COPB1,TMED10,AREG,TMED3,SCFD1,TMED2,ANKRD28,SPTBN4,SEC24D,COPG2,F7,MIA3,BCAP31,WHAMM,F2,COPB2,SEC24A,SEC13,SEC23B,TMEM115,COL7A1,DYNC2LI1,COG1,PROS1,ATL3,F5,DYNLL1,SPTBN2,ZW10,SEC31A,DYNC1I1,SPTAN1,TMED9,SPAST,DYNC2H1,CNIH2,LMAN1,MCFD2,NSF,ARF4
GO:0006022	aminoglycan metabolic process	GO_AMINOGLYCAN_METABOLIC_PROCESS	-0.183843101611956	-0.90322159390716	0.721098373238913	0.916707118448606	156	CHI3L1,AGRN,B3GALT6,GPC5,FMOD,ANGPT1,SDC1,UGDH,EXTL2,SPOCK2,HAS1,ITIH6,PIM1,HPSE,B4GALT7,B4GALT2,IDUA,NDST3,GALNT5,SGSH,B4GALT5,EXT1,HS3ST5,PGLYRP1,HGF
GO:0009595	detection of biotic stimulus	GO_DETECTION_OF_BIOTIC_STIMULUS	-0.245688190973918	-0.833405002165998	0.721517874799499	0.916707118448606	25	LY96,HLA-DRB5,PGLYRP1,NLRP3,NOD1,TLR2,HLA-DRB1
GO:0007413	axonal fasciculation	GO_AXONAL_FASCICULATION	-0.261559888343124	-0.823797002531337	0.721534384638777	0.916707118448606	19	CNR1,RTN4,SEMA3A
GO:0031000	response to caffeine	GO_RESPONSE_TO_CAFFEINE	0.279492639678737	0.816659332919938	0.721680141250813	0.916707118448606	16	HDAC2,RYR2,SLC8A1,CAD,DHODH,CASQ2,PPARGC1A
GO:0070373	negative regulation of erk1 and erk2 cascade	GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE	-0.216042503664462	-0.857627818842593	0.722067039106145	0.916707118448606	48	EZR,PTPN2,ITGB1BP1,ATF3,KLF4,NLRP6,ERRFI1,ADIPOQ,LMO3,NLRP12
NA	ncrna 3 end processing	GO_NCRNA_3_END_PROCESSING	0.2711535873088	0.818068103447476	0.722468759864085	0.916707118448606	18	ELAC2,EXOSC4,EXOSC7,EXOSC3
GO:0090281	negative regulation of calcium ion import	GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_IMPORT	0.261997476348967	0.824606993402521	0.722514441799088	0.916707118448606	21	CALM3,PLN,CALM1,SEMG1,SLC30A1,TRDN,CASQ2,GSTO1,TGFB1,CLIC2,CALM2,SLN
GO:0001709	cell fate determination	GO_CELL_FATE_DETERMINATION	-0.22368832323462	-0.851799846946617	0.722620380739082	0.916707118448606	40	CYP26B1,BMP4,GATA3,NKX6-3,KLF4,CTNNB1
GO:0046631	alpha beta t cell activation	GO_ALPHA_BETA_T_CELL_ACTIVATION	-0.214785870817953	-0.860222421030004	0.7227539503386	0.916707118448606	50	ELF4,GATA3,CEBPB,ANXA1,PLA2G2D,FUT7,IRF4,RPL22,NKX2-3,SEMA4A,PTGER4,ABL1,BCL2,ZAP70,PAX1
GO:0046827	positive regulation of protein export from nucleus	GO_POSITIVE_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS	0.267982843219352	0.820058936834501	0.722926395374694	0.916707118448606	19	PRKACA,GSK3B,XPO4,EMD,TPR,RANBP3
GO:0072528	pyrimidine containing compound biosynthetic process	GO_PYRIMIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	-0.232869954750243	-0.840950281859514	0.723071122840478	0.916707118448606	32	DTYMK,SHMT1,DUT,NME9,CPS1,TYMS,TK2,DCTD,UCK1,CMPK1
GO:0060444	branching involved in mammary gland duct morphogenesis	GO_BRANCHING_INVOLVED_IN_MAMMARY_GLAND_DUCT_MORPHOGENESIS	-0.257989688330132	-0.824422199514863	0.723750054392759	0.916851913686995	20	AREG,WNT5A,CSF1,MSX2
GO:0051205	protein insertion into membrane	GO_PROTEIN_INSERTION_INTO_MEMBRANE	0.261475843675083	0.822965214417218	0.725005998191315	0.916851913686995	21	BAD,MOAP1,OXA1L,COX18
GO:0007530	sex determination	GO_SEX_DETERMINATION	-0.254960328352017	-0.825425148313844	0.725135860669155	0.916851913686995	21	SOX3,WT1,DMRT1
GO:0060760	positive regulation of response to cytokine stimulus	GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS	-0.242542573092432	-0.83131922957998	0.725205111849196	0.916851913686995	26	WNT5A,RIPK2,CSF1,HIF1A,IRF7,TXK,EDN1
GO:0046006	regulation of activated t cell proliferation	GO_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION	0.231193959854963	0.842601550712668	0.725472482202869	0.916851913686995	38	STAT5B,HHLA2,PRKAR1A,IDO1,IL4,TMIGD2,IL2,HMGB1,CLC,TNFSF4,JAK3,PRNP,IL12RB1,FOXP3,RC3H1,BTN2A2,CD274,PDCD1LG2
GO:0090313	regulation of protein targeting to membrane	GO_REGULATION_OF_PROTEIN_TARGETING_TO_MEMBRANE	-0.263448532929953	-0.818127265087331	0.725712428215408	0.916851913686995	18	ITGB1BP1,CDK5,KCNB1,INPP5K,MFF,HPCA
GO:0016233	telomere capping	GO_TELOMERE_CAPPING	0.258395461479472	0.823047523136575	0.725893465412163	0.916851913686995	22	TFIP11,HIST1H4F,ACD,TERF2IP,PRKDC,MRE11A,HIST1H4A,DCLRE1A,HIST3H3
GO:1903409	reactive oxygen species biosynthetic process	GO_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS	-0.249423917859416	-0.827295145970713	0.725943810359965	0.916851913686995	23	DUOX2,SLC7A2,NQO1,CYP1A2,DDAH2
NA	modification of morphology or physiology of other organism	GO_MODIFICATION_OF_MORPHOLOGY_OR_PHYSIOLOGY_OF_OTHER_ORGANISM	-0.194316403986662	-0.881393693076403	0.726130177514793	0.916851913686995	95	PPIB,DEFA5,CCL3,C9,SNW1,AQP1,DEFA6,PC,SLC25A6,S100A12,KPNA7,TYMS,EIF2AK4,MBL2,INPP5K
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	GO_POSITIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS	0.224848799836179	0.846423551157643	0.726195407474111	0.916851913686995	44	AGT,AKT2,ESR1,HDAC4,JAK2,AGTR2,MTOR,TNF,PARK7,ITGB2,CYBA,PTX3,TLR4,TICAM1,HBB,HSP90AB1,DDAH1,DNM2,OGT,INSR
GO:0046174	polyol catabolic process	GO_POLYOL_CATABOLIC_PROCESS	-0.270548442025004	-0.812929987997924	0.726951966577916	0.916851913686995	16	MTMR7,GK,INPP5E,INPP5K
GO:2000243	positive regulation of reproductive process	GO_POSITIVE_REGULATION_OF_REPRODUCTIVE_PROCESS	-0.213465592393063	-0.858215208675881	0.727052374048568	0.916851913686995	51	WT1,WNT5A,RETN,DMRT1,IQCF1,SEMA3A,XBP1,CTNNB1,MSX2,SMURF2,EDNRB,NPM2,ACVR1B,PTGER4,PLB1,INHBA
NA	auditory receptor cell differentiation	GO_AUDITORY_RECEPTOR_CELL_DIFFERENTIATION	-0.242213242023842	-0.830190441150277	0.727140751820161	0.916851913686995	26	PDZD7,LRTOMT,ATP2B2
GO:0070664	negative regulation of leukocyte proliferation	GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION	0.209797984123988	0.861964807575833	0.727267925059868	0.916851913686995	67	CTLA4,PDE5A,SCGB1A1,XCL1,SPN,PELI1,INPP5D,PRKAR1A,CD300A,IDO1,SHH,PKN1,IL2,GNRH1,MAD1L1,LILRB1,TNFRSF14,FOXJ1
GO:0072527	pyrimidine containing compound metabolic process	GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	0.210114613111281	0.860787193523274	0.727271125830148	0.916851913686995	66	TK1,CMPK2,UPP2,UNG,ENTPD4,UCKL1,NME6,TET2,MTOR,AICDA,MAPK1,NME5,APOBEC3H,THTPA,TPK1,CAD,DHODH,UPB1,APOBEC1
GO:0034405	response to fluid shear stress	GO_RESPONSE_TO_FLUID_SHEAR_STRESS	-0.230703028913443	-0.839561911449394	0.728137050662648	0.91759989237382	33	ASS1,KLF4,XBP1,HDAC3,ABCA1,PKD2,NFE2L2,F3,MAP2K5,PTK2B,KLF2
GO:1901032	negative regulation of response to reactive oxygen species	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES	-0.266156102462821	-0.813986333321839	0.728749405199637	0.917846005802638	17	HP,MET,NR4A3,PYCR1,HGF,NFE2L2
GO:0070665	positive regulation of leukocyte proliferation	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION	-0.186635534072645	-0.894257500670441	0.72887771049033	0.917846005802638	132	CD55,TCF3,CCL19,IL18,ANXA1,TACR1,CLCF1,BST1,IL6ST,PYCARD,RIPK2,CSF1,CDKN1A,SLC39A10,LEP,TNFSF9,CHRNB2,LILRB2
GO:0043410	positive regulation of mapk cascade	GO_POSITIVE_REGULATION_OF_MAPK_CASCADE	0.173556041770202	0.92261063023004	0.729768830609167	0.918541561464829	432	P2RY1,CCL1,MADD,RAPGEF1,TAOK2,PDE5A,NRP1,MAPKAPK2,FBXW7,PDGFB,SERPINF2,TNIK,LPAR3,DRD4,DVL2,CYSLTR2,TIAM1,FLT1,ADRB2,ZAK,DIRAS2,NDRG4,IGFBP3,LRRK2,ESR1,BMPER,MAP3K15,TAOK3,SASH1,CRKL,XCL1,DRD2,OPRK1,HIPK2,ZEB2,ADRA2C,CDH2,CCL24,PLA2G5,SOX2,MAPKAPK3,VEGFB,HMGCR,OSM,PLCE1,FGF1,RAPGEF2,JAK2,PTEN,GH1,MAP3K4,DIRAS1,FZD10,CD40,GLIPR2,EZH2,MAPKAPK5,TGFA,CX3CL1,RAF1,FGFR1,PRKCZ,RELT,GCNT2,ERBB4,ANKRD6,ESR2,DBNL,DUSP19,S100A7,TNF,TNFRSF19,TEK,DSTYK,PIK3R5,MAPK1,CCL16,CDK1,VEGFA,PKN1,P2RX7,SOD1,ZNF622,GADD45A,EPHA4,IL11,MAPK8IP3,MAGED1,ADORA2B,PLCG1,MDFI,HMGB1,GRM4,GAB1,CD36,CCL23,ATP6AP1,DUSP7,MAP4K2
GO:0060841	venous blood vessel development	GO_VENOUS_BLOOD_VESSEL_DEVELOPMENT	-0.274268592718708	-0.807986286346216	0.730190680258858	0.918541561464829	15	SEMA3C,FOXF1
GO:0010975	regulation of neuron projection development	GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT	0.174769167131782	0.918949130746316	0.73055140652228	0.918541561464829	385	SEMA6A,CPEB3,SHANK3,XK,SF3A2,NLGN3,MARK2,RAPGEF1,CDKL5,NRP1,CBFA2T2,IL1RAPL1,SSH2,TNIK,HDAC2,LPAR3,SEMA6C,BARHL2,PAFAH1B1,GAK,TIAM1,RAB21,TRPV2,NDRG4,P2RY2,LRRK2,VLDLR,KIAA0319,MEGF8,SHANK1,NEDD4L,ZEB2,CDH2,MACF1,MOB2,INPP5J,ARF1,GSK3B,RAPGEF2,OBSL1,PTEN,DMD,RASAL1,CFL1,ARHGAP35,PPP1R9A,GOLGA4,EPHA3,LIMK1,NFATC4,ITSN2,GORASP1,EZH2,DNM3,GPRC5B,ULK4,FGFR1,EP300,FBXO31,SETX,EPHA7,MTOR,IKBKB,CCR2
GO:0060343	trabecula formation	GO_TRABECULA_FORMATION	0.260292877852712	0.819241965233002	0.730727349906797	0.918541561464829	21	BMP10,CAV3,EGLN1,NKX2-5,TEK,FHL2,HEY2,SRF,TGFBR3
GO:0007398	ectoderm development	GO_ECTODERM_DEVELOPMENT	-0.256542527327987	-0.819797705938539	0.730886384404508	0.918541561464829	20	EDA2R,CTNNB1,STX2,ZBTB17
GO:0031638	zymogen activation	GO_ZYMOGEN_ACTIVATION	0.197318746756871	0.875825683741469	0.731067392502756	0.918541561464829	104	KLKB1,CARD8,BAD,CYFIP2,DLC1,HSPD1,PDCD2,CTSH,NKX3-1,JAK2,ACER2,IFI27,DNAJA3,HIST1H2BA,MTCH1,TNFRSF10B,TNFSF10,CASP8AP2,TNF,PDCD6,CDKN1B,VCP
GO:0030212	hyaluronan metabolic process	GO_HYALURONAN_METABOLIC_PROCESS	0.244291354586088	0.827764296631547	0.731937459998171	0.919288601974162	28	ITIH3,ABCC5,HMMR,HAS3,HYAL1,ITIH2,HYAL2
GO:0032024	positive regulation of insulin secretion	GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION	0.210585904396088	0.857146172447199	0.73220818238049	0.919288601974162	64	BAD,PPARD,TRPM4,GIPR,GJA1,JAK2,PFKM,GCK,ANO1,STX4,GLUD1
GO:0072666	establishment of protein localization to vacuole	GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_VACUOLE	-0.233244799776165	-0.835466880792203	0.732788410419989	0.919379801598372	31	AP3M1,VPS25,SNF8,SORL1,GCC2,SNX16,PIK3R4,VPS41,HGS,GNPTG,SMURF1,NAGPA,VTI1B,SCARB2,TRAPPC8,VPS28
GO:0006310	dna recombination	GO_DNA_RECOMBINATION	0.185941031118887	0.893655133408145	0.733108612988393	0.919379801598372	177	RPA4,ZSWIM7,UNG,ZFYVE26,DMC1,UBE2N,MCRS1,HSPD1,IGHMBP2,EXD2,TEX11,POLA2,KLHDC3,RAD21L1,FBXO18,ERCC1,LIG3,SPO11,POLD2,ERCC4,SETX,MLH3,AICDA,MMS22L,RECQL5,RFC3,EXOSC3,RAD51AP1,NFRKB,CNTD1,HUS1,SFPQ,PRDM9,HFM1,ATRX,HMGB1,PSMC3IP,ENDOG,TSN,PRKDC,RNF168,MRE11A,UBE2B,FAN1,KIN,CCDC155,PRIM1,BRCA2,PAXIP1,TOP2B,WRN,NSMCE2,PALB2,INO80D,MLH1,EXO1,RMI1
GO:0035590	purinergic nucleotide receptor signaling pathway	GO_PURINERGIC_NUCLEOTIDE_RECEPTOR_SIGNALING_PATHWAY	0.262637965074373	0.815255825187319	0.733234641006662	0.919379801598372	20	P2RY1,P2RY2,P2RY13,P2RX7,PTAFR,P2RX2,GPR171
GO:0098773	skin epidermis development	GO_SKIN_EPIDERMIS_DEVELOPMENT	-0.203222928761973	-0.866420803303438	0.733563213070746	0.919379801598372	68	DNASE1L2,KRT71,FGF7,FGFR2,KRT25,EDAR,CTNNB1,EGFR,TMEM79,FZD3
GO:0002643	regulation of tolerance induction	GO_REGULATION_OF_TOLERANCE_INDUCTION	0.268614038654112	0.810406306411438	0.733646508346176	0.919379801598372	18	TGFBR2,IDO1,HLA-B,HMGB1,CLC,FOXJ1
GO:0006968	cellular defense response	GO_CELLULAR_DEFENSE_RESPONSE	-0.212558333994605	-0.854567674911651	0.734233417905038	0.919772863665187	51	CCR6,LY96,UMOD,NCR2,CD5L,CD300C,LILRB2,C5AR1,CLEC5A,PAGE1
GO:0097530	granulocyte migration	GO_GRANULOCYTE_MIGRATION	-0.205109161783446	-0.86188391318523	0.734958863813945	0.920339112945587	63	SCG2,CCL3,IRAK4,ANXA1,UMOD,S100A12,SAA1,IL17RC,C5AR1,S100A9
GO:0050873	brown fat cell differentiation	GO_BROWN_FAT_CELL_DIFFERENTIATION	-0.237241956527583	-0.828871769141108	0.735353178718803	0.920490442382853	28	CEBPB,UCP1,CEBPA,ADIPOQ,FABP4,RARRES2,LAMB3,RGS2,ZNF516
GO:0051149	positive regulation of muscle cell differentiation	GO_POSITIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION	0.203542666238868	0.86513908232604	0.736335926003784	0.921377965401017	81	EHD1,IGFBP3,PIN1,BMP10,CDH2,ZFHX3,CTNNA1,AKAP6,SMARCD3,CAV3,DDX39B,SMYD1,SHH,EP300,MTOR,IL4,SCGB3A1,TRIM32,MYLK3,CXCL9,GDF15,SETD3,PROX1,FLOT1,MEF2C,CTH
GO:0015697	quaternary ammonium group transport	GO_QUATERNARY_AMMONIUM_GROUP_TRANSPORT	-0.264465451637701	-0.808815808756244	0.736687286412597	0.921475067285322	17	SLC22A4,SLC38A2,SLC22A3
GO:0045787	positive regulation of cell cycle	GO_POSITIVE_REGULATION_OF_CELL_CYCLE	0.17754189215753	0.909912269600135	0.7372282565354	0.92149389959578	301	CCND2,CUL4A,LRP5,TAS2R13,PPP2R5C,DDX3X,PRKACA,PCID2,PDGFB,NPM1,STAT5B,LRP6,PAFAH1B1,APP,ROCK2,CREBBP,CCND1,SVIL,DRD2,MAD2L1,GOLGA2,PLAGL1,NKX3-1,USP2,SMARCD3,PTEN,RRP8,TFDP2,MED25,CNOT6L,GORASP1,E2F8,TGFA,CNOT4,PGGT1B,FAM83D,FGFR1,EP300,TAS1R2,KCNA5,ANAPC11,ANKRD17,PLK4,CDKN1B,CDK1,TRIM32,GADD45A,CDC25C,DLGAP5,SFPQ,PRDM9,DUSP3,CNOT8,ARID3A,RDX,ATRX,CCNL2,ASNS,FOXO4,TPR,PRKCE,FGF8,UBE2B,EGF,PROX1,TBX3,ESPL1,RASSF1,MSX1,MED1,CNOT1,CYP1A1,FOSL1,PPP1R1C,MAPRE3,BRCA2,ASCL1,CASP2,EREG,RBL2,PHOX2B,MDM4,NSMCE2,SIRT2,SIN3A,CENPV,PLK1,CCND3,HCFC1,RPS6KB1,E2F7,KIF23,PPP2R5B,CDKN2A,USP22,OVOL1,CCNT1,KIF3B,MEPCE,USP19,CITED2,DRD3,MTBP
GO:0060046	regulation of acrosome reaction	GO_REGULATION_OF_ACROSOME_REACTION	0.271539629284564	0.806665944457023	0.737390269305163	0.92149389959578	17	SPINK8,ZP2,ZP3,GLRA1,FAM170B,POMZP3,PLCB1,CRISP1
GO:0045840	positive regulation of mitotic nuclear division	GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION	0.22316968795399	0.840102682008465	0.7375236380009	0.92149389959578	44	LRP5,PDGFB,GOLGA2,PTEN,GORASP1,TGFA,ANAPC11,DLGAP5,FGF8,EGF,ESPL1,EREG,NSMCE2,PLK1
GO:0046112	nucleobase biosynthetic process	GO_NUCLEOBASE_BIOSYNTHETIC_PROCESS	-0.260710486273469	-0.809624387512582	0.738433199696608	0.922287996355764	18	SHMT1,GART,PAICS,CPS1
GO:0002821	positive regulation of adaptive immune response	GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	0.207136647378553	0.857741468981056	0.73892650585414	0.922420984717853	70	RSAD2,UNG,HLX,XCL1,HSPD1,CD40,HLA-B,PRKCZ,ADA,CCR2,IL4,TNF,EXOSC3,P2RX7,MALT1,IL2,ZP3,CD80
NA	modification by symbiont of host morphology or physiology	GO_MODIFICATION_BY_SYMBIONT_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY	0.22496560183605	0.837991983817418	0.739223826714801	0.922420984717853	42	BAD,HIPK2,CCR2,RXRA,KPNA4,KPNA3,HYAL2,SMAD3,VAPB,PTX3,NTRK3,APCS,CD4,KPNB1
NA	protein import into nucleus translocation	GO_PROTEIN_IMPORT_INTO_NUCLEUS_TRANSLOCATION	0.242915116874024	0.823101010680822	0.739361799396544	0.922420984717853	28	OR1D2,RANBP6,POLA2,TNF,BCL6,NFKBIA,MT3,RBM22,KPNB1
NA	regulation of organ morphogenesis	GO_REGULATION_OF_ORGAN_MORPHOGENESIS	0.18070976149545	0.899525545416861	0.740128423961635	0.922538133237064	233	AGT,FBXW7,TBX2,PRICKLE1,DVL2,PSMD11,TIAM1,ESR1,PSMD2,PSMC6,HAND2,BTBD7,NFIB,RNF207,BMP10,NACA,EYA1,PRICKLE2,FGF1,CAV3,PSMC5,PSMB7,MED12,AGTR2,PSME4,LIMS2,SIX1,SHH,FGFR1,ANKRD6,TBX5,TNF,ZNRF3,PSMA8,FZD6,RXRA,SOX17,VEGFA,PSMD8,AP2M1,PSMB10,SOX9,PLAU,WNT11,MAGED1,PSMD3,PSMB1,BCOR,AMELX,PSMA5,MLLT3,LHX1,PSMB9,CHAD,FGF8,HOXC11,HPN,TGFB3,MSX1,MED1,CELSR2,PSMD6,TWIST1,TACSTD2,PSMB3,PSMB6,PSMD1,SEC24B,HOXA11,SMO,SIX2,FOXC2,GNG5,ASPN
GO:0016447	somatic recombination of immunoglobulin gene segments	GO_SOMATIC_RECOMBINATION_OF_IMMUNOGLOBULIN_GENE_SEGMENTS	0.258278715978629	0.812902621853215	0.740176808223982	0.922538133237064	21	UNG,HSPD1,ERCC1,AICDA,EXOSC3,PRKDC,RNF168,MLH1,EXO1
GO:0008154	actin polymerization or depolymerization	GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION	-0.230070649122249	-0.830841305545258	0.740369475061542	0.922538133237064	32	COBLL1,WASF1,EVL,COBL
GO:1901881	positive regulation of protein depolymerization	GO_POSITIVE_REGULATION_OF_PROTEIN_DEPOLYMERIZATION	0.270817459199729	0.804520585361274	0.740552001190299	0.922538133237064	17	FAM21C,SEMA5A,CFL2,NES,ACTN2,SYNJ1,DSTN,SLN,VIL1,WDR1
GO:0070534	protein k63 linked ubiquitination	GO_PROTEIN_K63_LINKED_UBIQUITINATION	0.237418258412609	0.82483307824218	0.741149877866492	0.922941357343178	31	UBE2O,UBE2N,UBE2T,RNF152,ARIH2,PRPF19,RNF115,RNF168,UBE2B,UBE2D4,CDKN2A,RNF4,UBE2S,TRAF6
GO:0042133	neurotransmitter metabolic process	GO_NEUROTRANSMITTER_METABOLIC_PROCESS	0.252325849018834	0.813561281276877	0.74268028360457	0.924505116350955	23	CHAT,SLC5A7,PRIMA1,NAALAD2,TH,SLC22A2,GAD2
GO:0048854	brain morphogenesis	GO_BRAIN_MORPHOGENESIS	0.234515491046472	0.826759680898658	0.743039358600583	0.924525455457181	33	SHANK3,PROP1,PAFAH1B1,CDH2,PTEN,SLC4A10,FZD6,MKKS,FGF8,SMO,BBS2,DKK1,NF1
GO:0090184	positive regulation of kidney development	GO_POSITIVE_REGULATION_OF_KIDNEY_DEVELOPMENT	-0.220456962498742	-0.839494901652878	0.743628219484882	0.924525455457181	40	PAX8,WT1,BMP4,WNT2B,GATA3
GO:0031647	regulation of protein stability	GO_REGULATION_OF_PROTEIN_STABILITY	0.183199486828341	0.894370916465012	0.744064107637515	0.924525455457181	200	LSS,PIK3R1,SIAH1,ZSWIM7,FBXW7,ANK2,TMEM88,PIN1,TSC1,HSPD1,PINK1,CTSH,USP13,USP2,VPS11,BTRC,BAG3,PTEN,SIAH3,SEL1L,KAT2A,GTPBP4,DNAJA3,KHDRBS1,EP300,TCP1,AAK1,CREB1,PARK7,MAPK1,HDAC6,SOX17,TRIM24,PSMD8,USP28,CCT3,BAG6,SMAD7,SMAD3,SUMO1,TPR,PRKDC,CDC37L1,PFN2,UBE2B,QRSL1,CSN3,CHFR,RASSF1,MSX1,CDKN2AIP,DPM2,CCT7,TSPAN1,CCT4,ATP1B2
GO:0043620	regulation of dna templated transcription in response to stress	GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_IN_RESPONSE_TO_STRESS	-0.204504950614597	-0.856794016464856	0.744510978043912	0.924525455457181	62	CA9,CEBPB,MUC1,CREB3L1,ATF3,XBP1,HIF1A,ATF6,UBA52,MBTPS2
GO:0003197	endocardial cushion development	GO_ENDOCARDIAL_CUSHION_DEVELOPMENT	-0.232586992869209	-0.826512103986591	0.744682263883663	0.924525455457181	30	BMP4,BMP2,FOXF1,ACVR1,MSX2
GO:0031290	retinal ganglion cell axon guidance	GO_RETINAL_GANGLION_CELL_AXON_GUIDANCE	0.269823241905828	0.801567052447889	0.744755244755245	0.924525455457181	17	PTPRM,NRP1,POU4F3,EPHA7
GO:0006821	chloride transport	GO_CHLORIDE_TRANSPORT	0.197620092323677	0.868164353821089	0.744788332785496	0.924525455457181	98	TTYH2,BEST3,ANO2,SLC26A4,CLCN6,CLCN4,FXYD3,SLC4A3,FXYD1,SLC12A6,ANO1,SLC26A5,SLC4A10,BEST2,SLC26A7,SLC12A2,SLC26A3,GLRA3,NMUR2,BSND,SLC12A7,BEST4,APOL1,GABRA3,ANO5,CLCN7
GO:0030279	negative regulation of ossification	GO_NEGATIVE_REGULATION_OF_OSSIFICATION	0.209473092558497	0.849810465657404	0.745414955388755	0.924525455457181	63	LRP5,TRPM4,ADRB2,P2RY2,HAND2,HDAC4,SUFU,FGFR1,TNF,GFRA4,PTCH1,LIMD1,SOX9,BCOR,SMAD3
GO:0043574	peroxisomal transport	GO_PEROXISOMAL_TRANSPORT	0.265890447883434	0.802189255851829	0.745585532057114	0.924525455457181	18	PEX14,LONP2,PEX7,PEX26,PEX12,PEX3,PEX19,PEX13,PEX6,PEX2
GO:0014910	regulation of smooth muscle cell migration	GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION	0.218058117120761	0.839864654603562	0.74565393258427	0.924525455457181	49	PPARD,NRP1,PDGFB,NDRG4,IGFBP3,P2RY2,HDAC4,DOCK4
GO:1904019	epithelial cell apoptotic process	GO_EPITHELIAL_CELL_APOPTOTIC_PROCESS	-0.241359942089718	-0.818723041847056	0.745929555492079	0.924525455457181	25	KRT8,KRT18,STK3,FAS
GO:0001935	endothelial cell proliferation	GO_ENDOTHELIAL_CELL_PROLIFERATION	-0.24768463552337	-0.812021984904945	0.746142566369745	0.924525455457181	22	BMP4,ITGB1BP1,XBP1,ANGPT4,CD34,DLG1,MMP14,HMOX1,CALCA
GO:0034204	lipid translocation	GO_LIPID_TRANSLOCATION	0.256957204495542	0.808743316099584	0.746267279404979	0.924525455457181	21	ABCA4,ATP11A,RFT1,P2RX7,ABCB4,ATP8B1,ATP9B
GO:0048745	smooth muscle tissue development	GO_SMOOTH_MUSCLE_TISSUE_DEVELOPMENT	0.269242815906029	0.799842774159122	0.747228834994792	0.925376106914081	17	ITGA8,SIX1,MYLK,ENG,SOX9,PROX1,SRF
GO:0051350	negative regulation of lyase activity	GO_NEGATIVE_REGULATION_OF_LYASE_ACTIVITY	-0.238571489792005	-0.817708266903126	0.74841079559202	0.926498984171658	26	PRKCA,GABBR2,OPRM1,EDNRB,GRM2,HPCA,PALM,GRM3,GPR87,PDZD3
GO:0031128	developmental induction	GO_DEVELOPMENTAL_INDUCTION	-0.236713829817908	-0.819525179601492	0.749135443511972	0.926928648800035	27	BMP4,BMP2,WNT2B,CTNNB1
GO:0002763	positive regulation of myeloid leukocyte differentiation	GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION	-0.215557188724886	-0.839120381586852	0.749308631427479	0.926928648800035	44	PRKCA,TNFSF11,RIPK1,CSF1,IL20,SLC9B2,IL5,TESC,TRIB1,PF4,JUN,FOS,CALCA,GPR68
GO:0048011	neurotrophin trk receptor signaling pathway	GO_NEUROTROPHIN_TRK_RECEPTOR_SIGNALING_PATHWAY	0.276272289726858	0.79385943900494	0.750051116191751	0.926930604554161	15	ZFYVE27,RAF1,SORT1,AKT1S1,DDIT4
GO:0022037	metencephalon development	GO_METENCEPHALON_DEVELOPMENT	-0.191137843284187	-0.873445419480944	0.750439242129256	0.926930604554161	99	C5orf42,HAP1,SSTR3,SSTR2,RFX4,GART,CEND1,LPAR1,GBX2,LHX5,OTX1,ATP2B2
GO:0046635	positive regulation of alpha beta t cell activation	GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	-0.210453611730619	-0.846105867850654	0.750611634650236	0.926930604554161	51	CD55,CCL19,RARA,IL18,ANXA1,RIPK2
GO:0010769	regulation of cell morphogenesis involved in differentiation	GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION	0.176141129141502	0.907247086978142	0.750651289871648	0.926930604554161	316	SEMA6A,SHANK3,XK,NLGN3,ELL3,MARK2,CDKL5,NRP1,IL1RAPL1,UNC13D,CLASP1,C1QBP,SSH2,TNIK,HDAC2,LPAR3,SEMA6C,BARHL2,PAFAH1B1,TIAM1,RAB21,TRPV2,LRRK2,MEGF8,BCL9L,ZEB2,CDH2,MACF1,GSK3B,RAPGEF2,OBSL1,PTEN,CFL1,FAM21C,PPP1R9A,TGFBR2,GOLGA4,EPHA3,GLIPR2,LIMK1,NFATC4,GORASP1,EZH2,DNM3,EP300,FBXO31,GCNT2,EPHA7,TBX5,GBP1,CCR2,SEMA5A
GO:0046824	positive regulation of nucleocytoplasmic transport	GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT	0.192784750582035	0.871015601652402	0.750939079360743	0.926930604554161	116	PRKACA,PIK3R1,RBCK1,C8orf4,GSK3B,AKAP6,JAK2,DDX58,CSF3,UBR5,SHH,XPO4,KHDRBS1,EP300,ERBB4,PPP3R1,IL18R1,NCBP2,TNF,SEMA5A,TMEM173,EMD,CDK1,KANK1,HYAL2,SMAD3,TPR,BAMBI,RANBP3,EGF,TLR4,TGFB3,MED1,EDA,PRKCQ,JUP
GO:0002902	regulation of b cell apoptotic process	GO_REGULATION_OF_B_CELL_APOPTOTIC_PROCESS	-0.261422309442544	-0.799508954116086	0.750962495133452	0.926930604554161	17	NOC2L,SLC39A10,AURKB,BAX,MIF,IL10
GO:0035914	skeletal muscle cell differentiation	GO_SKELETAL_MUSCLE_CELL_DIFFERENTIATION	-0.211129769291561	-0.845579649163368	0.751467268623025	0.926994595404267	50	PAX7,KLF5,CDON,NUPR1,SOX11,ATF3
GO:0045599	negative regulation of fat cell differentiation	GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION	-0.221509563159181	-0.83320044267043	0.752284127552848	0.926994595404267	38	ID4,WNT5A,GATA3,WNT10B,MSX2,ADIPOQ
NA	positive regulation of stat cascade	GO_POSITIVE_REGULATION_OF_STAT_CASCADE	-0.199648526293147	-0.859032104240866	0.752358490566038	0.926994595404267	71	IL18,ARL2BP,CLCF1,STAT3,IL6ST,IL20,TNFRSF1A,LEP,IL24,IL5,FLT3,F2R,PTGER4,SOCS3,IL10,ISL1,CYP1B1,PTK2B,IFNA2,HPX,FGFR3,IGF1,IL23R,CRLF1
GO:0002221	pattern recognition receptor signaling pathway	GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY	-0.1899446078743	-0.874060218751608	0.75236326404267	0.926994595404267	103	IRAK4,COLEC12,LY96,SCARA3,IRAK1,RIPK2,RIPK1,CHUK,UBA52,IRF7,IRAK3,TLR10,CNPY3,IKBKG,CTSK,PGLYRP1,TLR9,NOD1,TLR2,UNC93B1,UBB,IKBKE,TAB2,PIK3R4,PGLYRP2,TLR3,TRIM5
GO:0060443	mammary gland morphogenesis	GO_MAMMARY_GLAND_MORPHOGENESIS	-0.219071793120185	-0.834220209404357	0.752721164613662	0.926994595404267	40	AREG,BMP4,WNT5A,FGFR2,CSF1,MSX2,CAPN1,BSX,EPHA2
GO:0031349	positive regulation of defense response	GO_POSITIVE_REGULATION_OF_DEFENSE_RESPONSE	-0.169439163034495	-0.92069382456778	0.753519969320112	0.926994595404267	343	PLA2G2A,C3,POLR3D,CNR1,CCL3,TNFSF11,MAPK13,IL17B,IL18,IRAK4,FFAR3,COLEC12,WNT5A,OSMR,KLK7,LY96,KRAS,SCARA3,MB21D1,RPS19,AGTR1,IRAK1,SLC25A6,S100A12,POLR3G,IL6ST,PYCARD,RIPK2,RIPK1,LPL,CHUK,UBA52,IRF7,TNFRSF1A,FABP4,IRAK3,IL17RC,TLR10,CNPY3,VAMP8,IKBKG,PSMB11,S100A9,IL17F,PAK3,KLK5,CTSK,PGLYRP1,PSMD10,CLEC4E,PRKACG,NLRP12,TLR9,NOD1,PDPK1,HMGB2,TXK,CREB3L3,CUL1,PSMD5,CCL4,PSMD13,TLR2,PSMB5,UNC93B1,FCER1A,CCL18,IL17RB,PTGER4,UBB,IFI16,IKBKE
GO:0021782	glial cell development	GO_GLIAL_CELL_DEVELOPMENT	0.205804512586276	0.850230121503432	0.753553751034859	0.926994595404267	69	LAMA2,AKT2,EIF2B5,SH3TC2,LAMB2,PRDM8,PTEN,MED12,SHH,SOD1,DICER1,HDAC11,EIF2B4,NKX2-2,TLR4,PLP1,ASCL1,MT3,SMO,SIRT2,CNTN2
GO:0048147	negative regulation of fibroblast proliferation	GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION	-0.235934733066482	-0.816827874565997	0.753584880724245	0.926994595404267	27	MORC3,NUPR1,B4GALT7,PPARG,BAX,MYC
GO:0042542	response to hydrogen peroxide	GO_RESPONSE_TO_HYDROGEN_PEROXIDE	-0.189796028520414	-0.873376507305346	0.754339595685406	0.926994595404267	103	AQP1,AREG,HP,LDHA,SDC1,ANXA1,KLF4,CAT,NR4A3,STAR,HIF1A,CASP3,RPS3,FAS,FABP1,KLF6,ADAM9,MDM2,PDGFD,NFE2L2,EEF2,F3,ABL1,SIRT1,OLR1,BCL2,TRPA1,PDCD10,PLA2G4A,STK24,JUN,CYP1B1,DUSP1,PTK2B,MAP3K5,KLF2
GO:0048511	rhythmic process	GO_RHYTHMIC_PROCESS	0.177434466667001	0.901355345985051	0.754416904479431	0.926994595404267	278	CHAT,METTL3,TPH2,OPRL1,EIF2B5,HS3ST2,STAT5B,HDAC2,CSNK2A1,DRD4,ADRB2,PPARA,ROCK2,DMC1,ESR1,LFNG,CREBBP,DRD2,OPRK1,SUV39H1,ZFHX3,RPE65,CTNNA1,PROKR1,USP2,BTRC,GSK3B,PTEN,PRKAA2,KDM5A,PTPRN,NFYA,EZH2,SPO11,EP300,SETX,MMP7,ESR2,THRAP3,CREB1,PCYT1B,NPY5R,NCOR1,VEGFA,SOHLH1,ETS1,SOD1,ENOX1,SFPQ,PROKR2,MAGED1,PPP1CB,HEBP1,EIF2B4,NCOA1,CENPI,RAI1,GNRH1,PRKDC,MAPK8,KDM5C,CBX3,MTA1,PROX1,NTRK3,TGFB3,NHLH2,AXL
GO:0007202	activation of phospholipase c activity	GO_ACTIVATION_OF_PHOSPHOLIPASE_C_ACTIVITY	0.243585485926178	0.809973849294342	0.754524285373769	0.926994595404267	26	AGT,PLCB2,ADCYAP1R1,PRKCE,CALCR,LPAR2,SELE
GO:0002090	regulation of receptor internalization	GO_REGULATION_OF_RECEPTOR_INTERNALIZATION	0.22894699888771	0.823473587035713	0.754648526077098	0.926994595404267	36	LRRTM2,DLG4,DRD2,PCSK9,ARF1,GH1,HAMP,VEGFA,FLOT1,MTMR2,SELE,ATAD1,DKK1
GO:0034142	toll like receptor 4 signaling pathway	GO_TOLL_LIKE_RECEPTOR_4_SIGNALING_PATHWAY	-0.26050745700471	-0.79671105703797	0.754704330146645	0.926994595404267	17	LY96,IRAK1,RIPK2
GO:0030832	regulation of actin filament length	GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH	-0.182556643195604	-0.886835538200723	0.754869930482203	0.926994595404267	144	WASF1,BAIAP2L2,ALOX15,LIMA1,ARPC5,ARHGAP18,SPTBN4,EVL,ACTR3,KIRREL,VILL,PLEKHH2,NPHS1,PYCARD,CCL21,TWF1,WHAMM,BAIAP2,TRIOBP,CDC42EP1,SCIN,PAK3,PICK1,CAPZA1,PFN3,SPTBN2,WIPF2,SSH3
GO:1904031	positive regulation of cyclin dependent protein kinase activity	GO_POSITIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY	0.232304914095082	0.818966524520043	0.755885568513119	0.927903290888096	33	CCND2,PDGFB,CCND1,CDKN1B,CCNL2,PROX1,MAPRE3,CCND3,CCNT1,CCNY,PSRC1,HSPA2,SPDYA
GO:1903829	positive regulation of cellular protein localization	GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION	0.175518824689621	0.905791349475874	0.756370159869184	0.928064488151665	322	PRKACA,BAD,PIK3R1,RBCK1,AKT2,FBXW7,GPHA2,NRXN1,DYNLL2,HNRNPM,EDEM2,GZMB,ITGAX,KIF5B,RNF31,MCRS1,KAT7,VAMP2,C8orf4,PINK1,STARD7,BAP1,PLAGL2,ABLIM3,VPS11,GSK3B,AKAP6,JAK2,DDX58,CDK5RAP3,CSF3,HUWE1,CYB5R1,PSMB7,KAT2A,UBR5,NMT1,SHH,SAE1,XPO4,EP300,TCP1,STX4,ERBB4,RAMP3,PPP3R1,PPP1R13B,IL18R1,TNF,SEMA5A,TMEM173,EMD,ARIH2,PARK7,CDK1,VEGFA,PSMD8,USP36,ANK3,CCT3,RDX,KANK1,HYAL2,AGR2,SMAD3,OAZ1,TPR,BID,KCNN3,BAMBI,BCAS3,MAPK8,RANBP3,TREM2,ARF6,EGF,TLR4,TGFB3,MED1,YWHAG,CCT7,WRAP53,CCT4,EDA,PRKCQ,WBP11,JUP,TP53BP2
GO:0042462	eye photoreceptor cell development	GO_EYE_PHOTORECEPTOR_CELL_DEVELOPMENT	-0.230447625001623	-0.818909729427176	0.756568317138494	0.928064488151665	30	PRKCI,PDE6C,GNAT1,TULP1,RDH13,NRL
GO:0014065	phosphatidylinositol 3 kinase signaling	GO_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING	0.254500560042308	0.801011309575435	0.756916375985088	0.928153195470239	21	PIK3R1,PREX2,C1QBP,IRS1,PIK3R5,PIK3R2,PIK3CB,SIRT2,PIK3CG,NF1
GO:0006801	superoxide metabolic process	GO_SUPEROXIDE_METABOLIC_PROCESS	0.234507139505012	0.814719335576656	0.757647015932043	0.928497390710868	31	ATP7A,PRDX2,SOD2,CYBA,SOD1,CCS,NOX4,MT3,SOD3,NOS2,NOX3
GO:0072676	lymphocyte migration	GO_LYMPHOCYTE_MIGRATION	0.221036747241448	0.82801260508298	0.757748761819	0.928497390710868	43	CCL1,XCL1,CCL24,CXCL11,CXCR3,CX3CL1,CCR2,S1PR1,CCL16
GO:0061387	regulation of extent of cell growth	GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH	-0.190889153225915	-0.869118495379417	0.758121887597818	0.928616547909118	97	SEMA3F,SEMA3C,NKX6-1,WNT5A,ULK2,EFNA5,RTN4,SEMA3A,SEMA3B,PLXNA2,SEMA3D,CDK5,RND2,FGF13,CDH4,SEMA3E,SEMA4B,NRCAM,SEMA4A,FSTL4,WDR36,PLXNA4,TTL,ABL1,RNF6,RAB11A,NRG1,WNT3,PLXNA1,CRABP2,SEMA7A,SPP1
GO:0035850	epithelial cell differentiation involved in kidney development	GO_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	0.251657089277975	0.801584295730565	0.758483548452431	0.928721580244046	22	PDGFB,PROM1,LAMB2,KLF15,MTSS1
GO:0055026	negative regulation of cardiac muscle tissue development	GO_NEGATIVE_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.270413014364816	0.790129257707392	0.75914877799461	0.929198104265403	16	PRICKLE1,GJA1,CAV3,TGFBR2,TBX5
GO:0098792	xenophagy	GO_XENOPHAGY	-0.190141194116973	-0.868891017092726	0.760577425328838	0.929953331124695	99	SNRPB2,CPA3,ALPK1,LENG9,FGF7,ANXA5,TMEM39A,HCAR1,LGALS8,FGFBP1,UBA52,MSTN,PHYHIP,ZCCHC17,HPR,SLC25A19,LMCD1,YIPF1,HIST1H3C,FABP1
GO:0014066	regulation of phosphatidylinositol 3 kinase signaling	GO_REGULATION_OF_PHOSPHATIDYLINOSITOL_3_KINASE_SIGNALING	0.189137462898728	0.870977316214765	0.760682892129465	0.929953331124695	131	AGT,PPP2R5C,PIK3R1,PPARD,PDGFB,PPP1R16B,FLT1,TSC2,STAMBP,NKX3-1,PIP5K1B,FGF1,JAK2,PTEN,CSF3,GH1,PIP4K2C,IRS1,PIP4K2B,FGFR1,ERBB4,TEK,SELP,MAPK1,PIK3IP1,SOX9,SERPINA12,CD80,PIP5K1C,GAB1,FGF6
GO:1903319	positive regulation of protein maturation	GO_POSITIVE_REGULATION_OF_PROTEIN_MATURATION	0.269973717800944	0.788845661691346	0.761044512591767	0.929953331124695	16	KLKB1,RHBDD1,HPN,CNTN2,CCBE1,TFR2
GO:0007162	negative regulation of cell adhesion	GO_NEGATIVE_REGULATION_OF_CELL_ADHESION	-0.175458087810649	-0.900975693333412	0.761106690963221	0.929953331124695	213	ASS1,CCL28,SPINT2,BMP4,BMP2,TNFRSF21,PTPN2,HOXA7,SPOCK1,ANGPT1,CEBPB,MUC1,EFNA5,HLA-DRB5,ADAM15,C1QTNF1,ITGB1BP1,ANXA1,PLXNB2,KLF4,PLA2G2D,MEN1,MIA3,CCL21,ADAMTS18,ADIPOQ,ADAM22,CASP3,LILRB2,CDH1,CORO1C,SEMA3E,THBS1,ZNF703,CASK,ABAT,IL2RA,MUC21,VTCN1,HLA-DRB1,CD164,PLXNB1,DLG1,PLA2G2F,ABL1,PAWR,IL20RB,CD276,PODXL,SWAP70,IL4R,IL10,MMP14
GO:0006884	cell volume homeostasis	GO_CELL_VOLUME_HOMEOSTASIS	-0.234631488481756	-0.812315921237442	0.76147051697174	0.929953331124695	27	AQP1,AQP3,ANO6,AQP8
GO:0048643	positive regulation of skeletal muscle tissue development	GO_POSITIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT	0.242230278942275	0.805467496162635	0.761510112029924	0.929953331124695	26	ADRB2,NACA,HMGCR,USP2,SHH,SOX17,GPC1,FLOT1,MEF2C
GO:0019882	antigen processing and presentation	GO_ANTIGEN_PROCESSING_AND_PRESENTATION	-0.175956626777255	-0.898752911615261	0.761699742694826	0.929953331124695	204	KIF2C,RAET1E,CTSE,KIF18A,AZGP1,KIF5A,HLA-DRB5,RAB33A,CALR,KIF3A,RAB3B,CANX,RAB3C,SEC24D,NCF4,BCAP31,RAB10,ULBP3,SEC24A,SEC13,AP1S3,MARCH1,PSMB11,DYNC2LI1,RAET1G,PSMD10,KIF4A,DYNLL1,KIF3C,SPTBN2,PSMD5,PSMD13,PSMB5,SEC31A,DYNC1I1,HLA-DRB1,ACTR1B,CD1A,ULBP2,PSMA6,PSMA4,DYNC2H1,ABCB5,SH3GL2,AP1S2,PSMC3,KIF2B,HLA-DRA,AP1M1,KDM5D,RAB35
GO:0010524	positive regulation of calcium ion transport into cytosol	GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL	0.216465413979772	0.830107246363334	0.762488761014206	0.930491950049222	48	CALM3,CAPN3,XCL1,ADCYAP1R1,CXCL11,AKAP6,CXCR3,CALM1,P2RX7,CXCL9,PLCG1,HTT,TRDN,JPH2
GO:0023019	signal transduction involved in regulation of gene expression	GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_REGULATION_OF_GENE_EXPRESSION	-0.255651911165296	-0.793915215886301	0.762791201646982	0.930491950049222	18	TBX6,T,MSX2,SMAD2
GO:1900076	regulation of cellular response to insulin stimulus	GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS	0.210871620907506	0.835220600315855	0.762970226421822	0.930491950049222	56	PIK3R1,ESRRA,AKT2,GRB10,TSC1,TSC2,PIK3R3,IRS1,PRKCZ,SERPINA12,KANK1,NCOA5,MARCKS,PRKCQ,PIK3R2,VWA2,GPLD1,RPS6KB1
GO:0061005	cell differentiation involved in kidney development	GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	-0.224755066574439	-0.817916410503515	0.764748902974159	0.931630961838753	33	OSR1,WT1,BMP4,POU3F3,NPHS1,MAGI2,CD34,BASP1
GO:0003170	heart valve development	GO_HEART_VALVE_DEVELOPMENT	-0.230207067986471	-0.811194189891306	0.765210660179144	0.931630961838753	29	BMP2,GATA3,CYR61,ACVR1
GO:0007599	hemostasis	GO_HEMOSTASIS	-0.170860500679772	-0.912178805300899	0.765220415150867	0.931630961838753	293	PDPN,PRKCA,C3,TYRO3,P2RX1,KDM1A,DGKB,PROCR,CD177,ENTPD2,HBE1,ANO6,GATA3,TREML1,ANXA5,SERPING1,DOCK11,MMRN1,PRTN3,ACTG1,PAPSS2,C4BPB,F7,SH2B1,STXBP3,IFNA14,GATA5,SERPINA5,F2,PLAUR,SAA1,PRKAR2B,CYP4F11,F13B,PRKAR1B,ITPR3,PROS1,LAT,PRKACG,CYP4F2,IFNA16,HIST1H3C,F5,STXBP1,RHOG,RAP2B,CAPZA1,VKORC1,F2RL3,PDPK1,NFE2,F2R,DGKA,RHOA,GNA13,PDGFD,VPS45,RAD51B,C1GALT1C1,CDC42,CLIC1,HNF4A,F3,EHD2,CLEC1B,HIST1H3I,PF4,SERPINC1,LMAN1,THBD,F13A1,SLC7A11,RAC1,ACTN1,BLOC1S3,GATA6,AVPR2,GP9
GO:1903020	positive regulation of glycoprotein metabolic process	GO_POSITIVE_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS	-0.26148898288574	-0.785708592989229	0.765612485659242	0.931630961838753	16	CCL19,CTNNB1,CCL21
GO:0006354	dna templated transcription elongation	GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION	-0.192902509790787	-0.861787803779501	0.765680751173709	0.931630961838753	87	TAF9B,POLR2H,TAF1D,LEO1,SSRP1,TBP,POLR2K,CD3EAP,TAF10,ELP4,GTF2H2,POLR1B,TAF4B,GTF2F1,UBTF,GTF2H1
GO:0032392	dna geometric change	GO_DNA_GEOMETRIC_CHANGE	0.201793878125834	0.848273435814361	0.765947738799291	0.931630961838753	76	CUL4A,DDX3X,MCM4,MCM7,IGHMBP2,HMGA1,CHD8,FBXO18,ZRANB3,GTF2H3,SETX,RECQL5,GTF2H5,ATRX,HMGB1,G3BP1,GINS1,MRE11A
GO:1903792	negative regulation of anion transport	GO_NEGATIVE_REGULATION_OF_ANION_TRANSPORT	0.232849362377951	0.808959924232744	0.766014072696781	0.931630961838753	31	GPM6B,AKT2,DRD2,AGTR2,MTOR,GABBR1,NPY5R,GRK6,MAOB,LILRB1
GO:0003159	morphogenesis of an endothelium	GO_MORPHOGENESIS_OF_AN_ENDOTHELIUM	0.268679651065252	0.785064482772506	0.766118390484156	0.931630961838753	16	CSNK2B,STARD13,DLL4,SOX17,PROX1
GO:0043525	positive regulation of neuron apoptotic process	GO_POSITIVE_REGULATION_OF_NEURON_APOPTOTIC_PROCESS	-0.213007487675963	-0.829194912945511	0.766755851338894	0.932031350486255	44	BBC3,CCL3,CTNNB1,CASP3,CDK5,NQO1,PAK3,MAP3K11,BAX,GRIK2,FOXO3,CDC42,PAWR
GO:1903708	positive regulation of hemopoiesis	GO_POSITIVE_REGULATION_OF_HEMOPOIESIS	-0.180884546113092	-0.884564005426819	0.76739700281913	0.932031350486255	151	PRKCA,TNFSF11,CCL19,KDM1A,RARA,GATA3,ANXA1,XBP1,RIPK2,RIPK1,CSF1,IL36B,HIF1A,IL20,LEP,TNFSF9,LILRB2,SCIN,RAG1,ZBTB1,ATP11C,SLC9B2,NLRP3,IL5,SART1,HMGB2,NKAP,ACVR1B,IL2RA,FOXO3,TESC,MAPK11,TRIB1,INHBA,IL4R,CD46,PF4,MMP14
GO:0045453	bone resorption	GO_BONE_RESORPTION	-0.246285260911807	-0.797339920801187	0.767912874571684	0.932031350486255	21	TNFSF11,CTNNB1,CTSK,ZNF675,RAC1,GPR55,PTK2B,RAB3D,IL7
GO:0019835	cytolysis	GO_CYTOLYSIS	0.247033337476751	0.796496908014711	0.767936519598839	0.932031350486255	23	C8B,GZMB,CAPN3,MICA,P2RX7,APOL1,BAK1
GO:0055072	iron ion homeostasis	GO_IRON_ION_HOMEOSTASIS	-0.200821649436827	-0.846118621227349	0.768132298408458	0.932031350486255	64	STEAP3,STEAP1,EPB42,NEO1,CP,FBXL5,HIF1A,BDH2,FTHL17,LCN2,SLC22A17,MYC,SCARA5,SLC25A37,SFXN3,STEAP4,PICALM,LTF,SRI,HMOX1,HPX,ACO1
NA	negative regulation of protein complex disassembly	GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY	0.185402191946035	0.874786280956835	0.768575643776824	0.932031350486255	155	CEP192,SPTB,SPAG5,TUBGCP5,WDR62,BIRC8,MAP1A,CLASP1,SBDS,TUBGCP2,ARHGEF2,GOLGA2,LMOD1,LMOD3,DYNC1H1,ADD1,GPSM2,SMC1A,MAP4,CAPZB,TMOD1,KIFC1,TNF,TUBG1,RGS14,NCOR1,HDAC6,APC,TUBGCP6,RDX,GAS2L2,HAUS8,TUBGCP3,CKAP5,UVRAG,ESPL1,CAPG,EML1
GO:0046634	regulation of alpha beta t cell activation	GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	-0.199165923074171	-0.849124161883861	0.76927171322117	0.932031350486255	68	CD55,CCL19,RARA,IL18,GATA3,IL27,ANXA1,RIPK2,IRF4
GO:0043537	negative regulation of blood vessel endothelial cell migration	GO_NEGATIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	-0.242905310826348	-0.796353202225793	0.769451314263203	0.932031350486255	22	ITGB1BP1,KLF4,ANGPT4,THBS1,RHOA,FGF2,PDCD10,MAP2K5,APOE
GO:0008334	histone mrna metabolic process	GO_HISTONE_MRNA_METABOLIC_PROCESS	0.237189356149722	0.803699667941279	0.769534607296333	0.932031350486255	28	DCP2,NCBP1,ZCCHC11,EXOSC4,TUT1
GO:0045956	positive regulation of calcium ion dependent exocytosis	GO_POSITIVE_REGULATION_OF_CALCIUM_ION_DEPENDENT_EXOCYTOSIS	-0.234929190102855	-0.805224216235744	0.769614851637595	0.932031350486255	26	NLGN1,IQCF1,CDK5,CACNA1I,UNC13B,KCNB1,STXBP1,PLB1,SYT1
GO:0048048	embryonic eye morphogenesis	GO_EMBRYONIC_EYE_MORPHOGENESIS	-0.226883787556793	-0.812682171153661	0.769714690767322	0.932031350486255	31	EFEMP1,MFAP2,WNT5A,SOX11
GO:0071364	cellular response to epidermal growth factor stimulus	GO_CELLULAR_RESPONSE_TO_EPIDERMAL_GROWTH_FACTOR_STIMULUS	0.249156674283645	0.793619912934856	0.769770396420615	0.932031350486255	22	STAT5B,MCM7,BAG4,SOX9,PLCG1,CAD,MED1
GO:0051321	meiotic cell cycle	GO_MEIOTIC_CELL_CYCLE	0.184688084999943	0.875716194804105	0.770335168420876	0.932118735347221	161	TUBGCP5,NSUN2,SUN1,DMC1,LFNG,TUBGCP2,SYCP2,GOLGA2,SPANXA2-OT1,TEX11,ZNF318,SPIRE1,KLHDC3,RAD21L1,PRKAR1A,SMC1A,SPO11,SMC2,ERCC4,MLH3,TUBG1,NCAPD3,PLD6,CNTD1,TDRKH,HUS1,PRDM9,TUBGCP6,HFM1,CCNA1,BAG6,DMRTC2,PSMC3IP,TUBGCP3,MRE11A,UBE2B,UBR2,ESPL1,CCDC155,BRCA2,TOP2B,PIWIL3,EREG,SPIRE2,SIRT2,RAD1,MLH1,EXO1,PLK1,MEI1,TOP3A,NCAPD2,PPP2R1A,ASZ1,BRDT,DUSP13,ATM,SLC26A8,TEX19,MAEL,PIWIL2
NA	negative regulation of sequence specific dna binding transcription factor activity	GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY	-0.184612278478578	-0.874836577329676	0.770396411686265	0.932118735347221	123	PTGIS,DAP,UFL1,KDM1A,WWP2,TCEAL7,ANXA4,KLF4,IRAK1,MEN1,CAT,PYCARD,PIM1,MSX2,IRAK3,CEBPG,KEAP1,EIF2AK4,PSMD10,ZNF675,NLRP3,NLRP12,TLR9,CMKLR1,GLIS2,HNF4A,SFRP5,TRIB1,TRIM37,MED13,SIRT1
GO:0050731	positive regulation of peptidyl tyrosine phosphorylation	GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION	0.185480142699413	0.873649497751467	0.771161293567369	0.932398079266041	153	EHD4,AGT,NRP1,FBXW7,PDGFB,HDAC2,DVL2,UNC119,ITGB3,ARHGEF2,ADRA2C,CTF1,VEGFB,OSM,JAK2,CSF3,GH1,CD40,TGFA,GPRC5B,ERBB4,MTOR,IL4,CSF2,CNTN1,VEGFA,IL11,IL2,CD80,CD36,MLST8,LRRK1,TNFRSF18,TNFRSF14,TREM2,EGF,TEC,CSPG4,IL21
GO:0031338	regulation of vesicle fusion	GO_REGULATION_OF_VESICLE_FUSION	0.210233949798171	0.829553055760733	0.771181299072091	0.932398079266041	55	AKT2,ADPRHL1,SGSM1,VPS11,TBC1D13,RUNDC1,TBC1D4,GRIK5,RABGAP1L,TBC1D10B,TBC1D8,TBC1D21,TBC1D26,STXBP6,TBC1D30,RAB3A,DOC2B,TMEM27
GO:0060401	cytosolic calcium ion transport	GO_CYTOSOLIC_CALCIUM_ION_TRANSPORT	0.213401150598308	0.825470612072567	0.771785573228968	0.932655090826769	50	ITPR1,TRPV1,CACNA2D1,RYR2,TPCN1,XCL1,DRD2,SLC8A1,TRPM1,CACNA1C,P2RX7,TRDN,ATP2A2,JPH2,PRKCE
GO:0045580	regulation of t cell differentiation	GO_REGULATION_OF_T_CELL_DIFFERENTIATION	-0.188317831353983	-0.864503773325386	0.772191748151681	0.932655090826769	102	CCL19,RARA,CYP26B1,BMP4,PTPN2,GATA3,IL27,ANXA1,XBP1,RIPK2,IL36B,IRF4,TNFSF9,LILRB2,RAG1,ZBTB1,PRELID1,NLRP3,SART1
GO:0032692	negative regulation of interleukin 1 production	GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_1_PRODUCTION	0.263474933055525	0.782708057287857	0.772225115310222	0.932655090826769	17	PYDC2,GHSR,MEFV
GO:0051225	spindle assembly	GO_SPINDLE_ASSEMBLY	0.204692981120833	0.836003701710249	0.773497417091275	0.933856637707758	65	CEP192,TUBGCP5,BIRC8,CLASP1,TUBGCP2,GOLGA2
GO:0036296	response to increased oxygen levels	GO_RESPONSE_TO_INCREASED_OXYGEN_LEVELS	-0.240134950349562	-0.796485278986292	0.774122036874451	0.934079239107378	23	WNT5A,CAT,CDKN1A,PPARG,FAS
GO:0030262	apoptotic nuclear changes	GO_APOPTOTIC_NUCLEAR_CHANGES	0.245690237274959	0.792166418985142	0.774236802468682	0.934079239107378	23	ACIN1,CDK5RAP3,DICER1,DNASE2B,CECR2,HMGB1,ENDOG,H1F0
GO:2000191	regulation of fatty acid transport	GO_REGULATION_OF_FATTY_ACID_TRANSPORT	0.23953079627101	0.79649113879867	0.77458332569354	0.934162477350218	26	AKT2,P2RY2,AGTR2,NCOR1,P2RX7
GO:0045665	negative regulation of neuron differentiation	GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION	0.182561658359907	0.877413458315837	0.775218770237285	0.934575986760017	177	SEMA6A,NLGN3,ZHX2,ZNF536,NRP1,CBFA2T2,NOTCH3,HDAC2,SEMA6C,PAFAH1B1,DIXDC1,GAK,APP,KIAA0319,SOX2,INPP5J,GSK3B,RAPGEF2,PTEN,REST,NFATC4,GORASP1,DNM3,SHH,GDF11,EPHA7,OLIG2,DTX1,CCR2,SEMA5A,PAX6,PRPF19,HMG20A,SOX9,EPHA4
GO:1902622	regulation of neutrophil migration	GO_REGULATION_OF_NEUTROPHIL_MIGRATION	0.232523212324595	0.801386267397549	0.775860496506941	0.934575986760017	30	C1QBP,XCL1,LBP,CXCL2,DAPK2
GO:0001818	negative regulation of cytokine production	GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION	-0.176072371340717	-0.891291154897573	0.775974108068472	0.934575986760017	191	APOA2,EZR,TRAF3IP1,RARA,TNFRSF21,ANXA4,ANGPT1,GATA3,HLA-DRB5,CIDEA,TSPO,ANXA1,KLF4,ERRFI1,PYCARD,UBA52,ADIPOQ,IRAK3,CDH3,ORM1,POMC,PGLYRP1,HGF,NLRP3,NLRP12,TLR9,CMKLR1,CD34,THBS1,HLA-DRB1,ELANE,PTGER4,UBB,IKBKE,INHBA,IL20RB,CD276,CUEDC2,BANK1,IL10,TRIM27,RAC1,MAP2K5,PGLYRP2,GATA6,FURIN
GO:1903729	regulation of plasma membrane organization	GO_REGULATION_OF_PLASMA_MEMBRANE_ORGANIZATION	-0.198302687851996	-0.845443844120539	0.776168105343547	0.934575986760017	68	EZR,ITGA3,PRKCI,ARHGEF16,SH3GLB1,DAB2,ANXA13,RHOQ,VAMP8,PPP2R5A,S100A9,RHOG,EPHA2,TMEM59,PDPK1
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	GO_NEGATIVE_REGULATION_OF_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY	-0.200436836051356	-0.839750242191402	0.776424163167917	0.934575986760017	62	VASN,TGFBR1,HTRA1,SNX25,SKIL,CIDEA,UBA52,SMAD2,SMURF2,ONECUT1,PDPK1,UBB,PMEPA1,SIRT1,EID2
GO:0022408	negative regulation of cell cell adhesion	GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION	-0.182781232960474	-0.875789754447687	0.776592107833561	0.934575986760017	132	ASS1,CCL28,SPINT2,BMP4,BMP2,TNFRSF21,PTPN2,CEBPB,HLA-DRB5,C1QTNF1,ANXA1,KLF4,PLA2G2D,CCL21,ADAMTS18,ADIPOQ,CASP3,LILRB2,CDH1,ZNF703,ABAT,IL2RA,MUC21,VTCN1,HLA-DRB1,DLG1,PLA2G2F,ABL1,PAWR,IL20RB,CD276,PODXL,SWAP70,IL4R,IL10
GO:0032528	microvillus organization	GO_MICROVILLUS_ORGANIZATION	-0.255108770491788	-0.78020023125286	0.778431457369036	0.935801423988589	17	EZR,KLF5
GO:0001824	blastocyst development	GO_BLASTOCYST_DEVELOPMENT	-0.201294101575179	-0.837822068620693	0.778974570069521	0.935801423988589	60	TGFBR1,RBBP8,DAD1,NEK2,SKIL,MED21,NLE1,PRDM14,HOPX,GINS4,ETV2,CAPN2,SALL4,NODAL,JUNB,RAD51B
GO:0042749	regulation of circadian sleep wake cycle	GO_REGULATION_OF_CIRCADIAN_SLEEP_WAKE_CYCLE	-0.236936545134732	-0.79544467038101	0.77910343012545	0.935801423988589	24	NLGN1,NPY2R,HCRTR2,CHRNB2
GO:1903513	endoplasmic reticulum to cytosol transport	GO_ENDOPLASMIC_RETICULUM_TO_CYTOSOL_TRANSPORT	-0.243812086624319	-0.789333105520352	0.779458303323949	0.935801423988589	21	CCL3,RYR1,AUP1
GO:0042743	hydrogen peroxide metabolic process	GO_HYDROGEN_PEROXIDE_METABOLIC_PROCESS	0.233706968129002	0.798749141771884	0.779637505247595	0.935801423988589	29	PRDX2,HBA1,PARK7,CYBA,SOD1,TPO,MAOB,PRDX3,CYP1A1,PRDX5,HBB,PXDNL,PRDX6
GO:0070301	cellular response to hydrogen peroxide	GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE	0.207572370512115	0.827935603281399	0.779692088635757	0.935801423988589	58	HDAC2,IL18BP,PPIF,GSK3B,EZH2,PPP5C,EP300,SETX,FOXO1,PARK7,HDAC6,CDK1,ETS1,IMPACT,FXN,PCGF2,TRPC6,AIFM1,BNIP3,ARG1
GO:1901224	positive regulation of nik nf kappab signaling	GO_POSITIVE_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING	-0.229239598473773	-0.80091327151933	0.779950129090628	0.935801423988589	28	CHI3L1,TRAF4,CARD14,IRAK1
NA	reciprocal dna recombination	GO_RECIPROCAL_DNA_RECOMBINATION	0.230298709840253	0.800098505577487	0.780269058295964	0.935801423988589	31	DMC1,TEX11,KLHDC3,SPO11,ERCC4,MLH3,CNTD1,HFM1,MRE11A,UBE2B,TOP2B,MLH1
GO:0046849	bone remodeling	GO_BONE_REMODELING	-0.220996992076798	-0.810040511391866	0.780571225514147	0.935801423988589	34	TPH1,TNFSF11,CTNNB1,HTR1B,CTSK,ZNF675,EPHA2,RASSF2,RAC1,GPR55,PTK2B,RAB3D,IL7
NA	cofactor transport	GO_COFACTOR_TRANSPORT	0.240314622226404	0.791188482413807	0.781340037804408	0.935801423988589	25	SLC25A17,MFSD3,SLC5A6,FLVCR1,SLC25A32,P2RX7,ABCG2,SLC25A26
GO:0006536	glutamate metabolic process	GO_GLUTAMATE_METABOLIC_PROCESS	-0.236335938540978	-0.793428310626435	0.782195806649706	0.935801423988589	24	TAT,UROC1,AMDHD1,GGT1,FTCD,OAT
GO:0044283	small molecule biosynthetic process	GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS	0.171094447835673	0.904684555290964	0.782495747641874	0.935801423988589	408	IDI2,CNBP,CHAT,LSS,LPIN1,HSD17B8,HMGCLL1,PCYT1A,SLC27A5,ATPIF1,NDUFAB1,ACADM,MMAA,CHPT1,OTC,FOLH1B,FADS1,THNSL1,PGAM2,PGAM1,MTR,LIPT2,PRKAB2,THNSL2,LCAT,PLA2G5,QKI,HAAO,SLC25A11,TMLHE,HMGCR,FPGS,IMPA2,MVD,LIAS,CYP27B1,CYP51A1,PRKAA2,ACER2,CYB5R1,CYP7B1,PSPH,COQ9,IP6K3,GGPS1,MGLL,IDO1,MDH2,MSMO1,MMACHC,MDH1,ACAT1,ELOVL6,PTGDS,GLUD1,GOT2,IPMK,INSIG1,GATM,PCYT1B,HMGCS2,ALDOC,GGT7,PARK7,ACOT8,HMGCS1,ALDOA,SQLE,ENO2,RFK,EIF2B4,GOT1,PTAFR,CRTC2,CYP3A4,IDI1,ACACB,HOGA1,SGMS1,ASNS,GLUD2,FDFT1,MECR,CAD,PRKAG3,UPB1,NDUFA9,NAALAD2,SLC27A1,SHMT2,SLC25A12,CYP1A1,CHKA,PLP1,SCP2,SLC25A10,CSPG4,NSDHL,ADM,PRKAG1,APOA5,COQ2,HSD17B3,GPI,ACMSD,CTH,TKT,ISYNA1
GO:0071902	positive regulation of protein serine threonine kinase activity	GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	0.175827714066136	0.890135943196631	0.782545068587878	0.935801423988589	270	CCND2,MADD,PDE5A,MAPKAPK2,PDGFB,LPAR3,DRD4,DVL2,TIAM1,ALS2,FLT1,ZAK,DIRAS2,LRRK2,CALM3,CCND1,STRADA,TAOK3,SASH1,ZEB2,ADRA2C,MAPKAPK3,PLCE1,FGF1,RAPGEF2,GH1,MAP3K4,DIRAS1,FZD10,CD40,EZH2,MAPKAPK5,TGFA,CALM1,FGFR1,TNFRSF10B,DBNL,DUSP19,TNF,PIK3R5,CDKN1B,MAPK1,CDK1,VEGFA,PKN1,P2RX7,SOD1,GADD45A,EPHA4,MAPK8IP3,MAGED1,MALT1,ADORA2B,CCNL2,MDFI,GRM4,GAB1,DUSP7,MAP4K2,CARD10,PDE6H,MARCKS,EGF,PROX1,SLC27A1,NTRK3,TLR4,TGFB3
GO:0051654	establishment of mitochondrion localization	GO_ESTABLISHMENT_OF_MITOCHONDRION_LOCALIZATION	0.267707383758727	0.76924846027192	0.782635364969609	0.935801423988589	15	RHOT2,MAP1S,OPA1,NEFL,MAPT,LRPPRC,MAP1B
GO:0034333	adherens junction assembly	GO_ADHERENS_JUNCTION_ASSEMBLY	0.227444100038675	0.801830236165484	0.78265306122449	0.935801423988589	33	TAOK2,TESK2,TBCD,DLC1,PTPRK,PIP5K1C,SMAD7,LAMA5,JUP,SORBS1,VCL,ACTN2
GO:0001708	cell fate specification	GO_CELL_FATE_SPECIFICATION	-0.196911945122113	-0.842449055597831	0.78277162221554	0.935801423988589	69	TBX6,NKX6-1,CDON,FOXA1,HOXC10,OLIG3,CTNNB1,EVX1,ISL2,PRDM14,SOX6,APC2
GO:0007568	aging	GO_AGING	-0.171925421361339	-0.899673695769405	0.782858778824632	0.935801423988589	246	ASS1,TIMP1,BBC3,CNR1,MORC3,SEC63,RETN,CTGF,HELT,SERPING1,TSPO,SNCA,CALR,ZNF354A,MBD3,IRAK1,CANX,KRTAP4-9,KRT25,CAT,STAT3,CISD2,CP,DDC,CDKN1A,SLC6A3,SERP1,SCAP,TYMS,SLC18A2,MME,SPEF2,NQO1,KRT14,EDNRB,FAS,CHEK2,PTGS1,DCN,AURKB,TIMP2,BAX,KRT16,HSD17B10,KRTAP4-8,SLC32A1,LRP1,ABAT,MIF,EDN1,KRT33B,AMFR,EEF2,F3,SOCS3,SIRT1,MNT,ATP2B1,SERPINF1,IL10,BCL2,PLA2G4A,HTR2A,ALDH3A1,HRAS,JUN,SRR,FURIN
NA	atp hydrolysis coupled transmembrane transport	GO_ATP_HYDROLYSIS_COUPLED_TRANSMEMBRANE_TRANSPORT	-0.221589879216827	-0.806397832873357	0.783076991268118	0.935801423988589	33	ATP6V1C2,ATP6V1B1,ATP6AP1L,ATP6V0D1,ATP6V1H
GO:0046473	phosphatidic acid metabolic process	GO_PHOSPHATIDIC_ACID_METABOLIC_PROCESS	-0.225724367205954	-0.80212534397977	0.783572013546117	0.935801423988589	30	PLA2G2A,LIPC,GPD1,PLA2G2D
GO:0008206	bile acid metabolic process	GO_BILE_ACID_METABOLIC_PROCESS	-0.221215540010197	-0.805035557998473	0.784872124462568	0.935801423988589	33	ABCB11,STAR,LEP,SLCO1B3,CYP7A1,HSD3B7,SULT2A1,AKR1C1,CYP8B1,CYP46A1,SLCO1A2,ARV1,NR1H4,CYP39A1,SLC27A2,NR5A2,HSD17B4,CH25H
GO:0033197	response to vitamin e	GO_RESPONSE_TO_VITAMIN_E	0.267106615410557	0.767522171962941	0.784921652818826	0.935801423988589	15	CCND1,ALAD,ADA,HMGCS1
GO:0016445	somatic diversification of immunoglobulins	GO_SOMATIC_DIVERSIFICATION_OF_IMMUNOGLOBULINS	-0.230341006718904	-0.797461876418922	0.785039318046653	0.935801423988589	27	TCF3,PMS2P1,EXOSC6,MSH3,POLQ,RNF8,NBN,SWAP70,PMS2
GO:1902883	negative regulation of response to oxidative stress	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS	-0.222508932409999	-0.803534099652903	0.785300836087024	0.935801423988589	32	HP,MET,NONO,NR4A3,PYCR1,HIF1A
GO:0007346	regulation of mitotic cell cycle	GO_REGULATION_OF_MITOTIC_CELL_CYCLE	0.170336699415228	0.90615686999781	0.785406867718036	0.935801423988589	435	CUL4A,LRP5,PPP2R5C,FOXN3,DDX3X,PCID2,AURKAIP1,CDC26,RNF40,PDGFB,NPM1,STAT5B,CSNK2A1,PSMD11,PAFAH1B1,APP,PIN1,CREBBP,CCND1,PSMD2,PSMC6,TAOK3,MAD2L1,GOLGA2,PLAGL1,NKX3-1,FZR1,KANK2,ZNF655,USP2,PKIA,BTRC,SMARCD3,OBSL1,PTEN,CDK5RAP3,ANAPC1,TFDP2,PSMC5,PSMB7,PSME4,CNOT6L,GORASP1,SMC1A,EZH2,CEP85,TGFA,CNOT4,SAE1,PRCC,DGKZ,EP300,FBXO31,NME6,INTS3,MYO16,DAPK3,KCNA5,ANAPC11,ANKRD17,PSMA8,CDKN1B,CDK1,PSMD8,ATF2,PTCH1,PSMB10,APC,HUS1,GADD45A,CDC25C,DLGAP5,DUSP3,CNOT8,ARID3A,CUL9,RDX,ATRX,PSMD3,CLSPN,PSMB1,AATF,SMAD3,GBF1,ASNS,GIGYF2,PSMA5,KLHL22,FOXO4,TPR,ZWILCH,PSMB9,BID,PRKDC,MAD1L1,FGF8,MRE11A,TOM1L2,EGF,CTDSP2,CHFR,ESPL1,CNOT1,CYP1A1,MAD2L1BP,CCDC8,TIPIN,RINT1,PRKCQ,PPP1R1C,PSMD6,BRCA2,TOP2B,ASCL1,PSMB3,PSMB6,CASP2,EREG,PSMD1,RBL2,CHMP1B,RNF20,PHOX2B,MDM4,NSMCE2,SIRT2,SIN3A,TTC28,CHMP4B,PLK1,USP44,RPS6KB1,THAP1,MAEA,CHMP4C,E2F7,NEK7,CDKN2A,PSME2,USP22,OVOL1
GO:0006275	regulation of dna replication	GO_REGULATION_OF_DNA_REPLICATION	0.184122859384085	0.866506667648743	0.785442411844598	0.935801423988589	152	HMBOX1,FBXW7,PDGFB,SMG6,PARM1,GLI2,MCRS1,OBFC1,MAP3K4,UCN,FBXO18,ZRANB3,DACH1,E2F8,GTPBP4,SMC1A,LIG3,MAPKAPK5,TCP1,ACD,ANKRD17,CSF2,RFC3,MAPK1,CDK1,CCDC88A,HUS1,WRNIP1,CCT3,ATRX,MRE11A,TGFB3,CCT7,TIPIN,WRAP53,CCT4,PRKCQ,PKIB,BRCA2,EREG,MAP2K7,HNRNPU,E2F7,NEK7,RBBP6,SHC1,PPP2R1A,ATM,MAPK3,CCT8,INSR,PDGFRA,ESCO1,ATR,NAT10,TNKS,SENP2,TGFB1,INO80,HNRNPC,ZBTB38,DKC1
GO:0070527	platelet aggregation	GO_PLATELET_AGGREGATION	0.221362271836408	0.806769318868225	0.785531023018827	0.935801423988589	38	GNAS,MYL12A,ITGB3,MYL9,ITGA2B,HSPB1,METAP1,TSPAN32,PIK3CB,VCL,FGG,PIK3CG,HBB
GO:0032728	positive regulation of interferon beta production	GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION	-0.225318714427821	-0.80068383202329	0.785763297107063	0.935801423988589	30	POLR3D,POLR3G,RIPK2,IRF7,TLR9,IFNAR1,HMGB2,TLR2
GO:0003091	renal water homeostasis	GO_RENAL_WATER_HOMEOSTASIS	0.227900592915582	0.79786873087824	0.786053796142849	0.935801423988589	32	GNAS,PRKACA,ADCY7,PRKAR1A,ADCY5,ADCY8,ADCY9,ADCY4
GO:1902807	negative regulation of cell cycle g1 s phase transition	GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION	0.194317193512413	0.844731858181628	0.786662041453473	0.935801423988589	92	PPP2R5C,NPM1,CCND1,PLAGL1,KANK2,ZNF655,PTEN,TFDP2,CNOT6L,EZH2,CNOT4,DGKZ,EP300,FBXO31,MYO16,CDKN1B,CDK1,GADD45A,CDC25C,CNOT8,ARID3A,GIGYF2,PRKDC,CTDSP2,CNOT1
GO:0098801	regulation of renal system process	GO_REGULATION_OF_RENAL_SYSTEM_PROCESS	-0.217894564873539	-0.809906777778578	0.786705884974486	0.935801423988589	36	NPR1,ANPEP,TACR1,AGTR1,ADIPOQ,EDNRB,INPP5K,F2R,EDN1,PTGER4
GO:0002639	positive regulation of immunoglobulin production	GO_POSITIVE_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION	-0.225051129432355	-0.799732952376629	0.786914274330994	0.935801423988589	30	RBP4,MZB1,CLCF1,XBP1,WHSC1,IL5
GO:0010543	regulation of platelet activation	GO_REGULATION_OF_PLATELET_ACTIVATION	-0.225060833973172	-0.799767438055941	0.786914274330994	0.935801423988589	30	PRKCA,C1QTNF1,F2,ADAMTS18,TXK,ABAT,THBD,ZAP70,APOE
GO:0010831	positive regulation of myotube differentiation	GO_POSITIVE_REGULATION_OF_MYOTUBE_DIFFERENTIATION	0.232099022942073	0.793253606707791	0.787157537372004	0.935801423988589	29	EHD1,CAV3,SMYD1,MTOR,IL4,SCGB3A1,CXCL9,GDF15,FLOT1
GO:0030219	megakaryocyte differentiation	GO_MEGAKARYOCYTE_DIFFERENTIATION	0.250033423443208	0.776130004266063	0.78719467061436	0.935801423988589	20	EP300,FLI1,IL11,C6orf25,MED1,SRF,ABI1,VPS33B,TAL1,MEIS1
GO:0000271	polysaccharide biosynthetic process	GO_POLYSACCHARIDE_BIOSYNTHETIC_PROCESS	0.219999667094491	0.806141886282155	0.787340948525159	0.935801423988589	39	AKT2,PGM5,NDST1,PHKG1,GYS1,GCK,HAS3,GYG1,EPM2A,PRKAG3,PHKG2,PPP1R3C
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	GO_POSITIVE_REGULATION_OF_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY	-0.250362130653913	-0.777488046546775	0.787820999024813	0.935834350130211	18	C3,VAMP8,FCER1A,IL4R,ZAP70
GO:0043330	response to exogenous dsrna	GO_RESPONSE_TO_EXOGENOUS_DSRNA	-0.20992328735973	-0.817188747149988	0.787957820896193	0.935834350130211	44	COLEC12,MB21D1,RIPK2,IFNA14,IRAK3,IFNE,IFNA16,SLC3A2,DDX21,CARD9,TLR3,IFNA2,RFTN1
GO:0048791	calcium ion regulated exocytosis of neurotransmitter	GO_CALCIUM_ION_REGULATED_EXOCYTOSIS_OF_NEUROTRANSMITTER	0.227469590050589	0.796359811114158	0.788202728050846	0.935834350130211	32	C2CD4A,SYT9,SYT8,SYTL2,SYT7,SYT12,SYTL3,RPH3AL,C2CD4B,DOC2B,SYTL4
GO:0034394	protein localization to cell surface	GO_PROTEIN_LOCALIZATION_TO_CELL_SURFACE	0.245104289209097	0.780712157205302	0.788495884811548	0.935852308982959	22	ANK2,FCN1,PTPRK,FBLN5,WNT11,ARF6,EMP2,VCL
GO:0046847	filopodium assembly	GO_FILOPODIUM_ASSEMBLY	-0.252561501098137	-0.77240990649782	0.789116234805554	0.936258458355832	17	EZR,TTYH1,RAB17,SRGAP2,CDC42
GO:0043543	protein acylation	GO_PROTEIN_ACYLATION	0.185519457567899	0.861006638463087	0.789467461617714	0.936345128895428	138	TRIM16,DBI,NAA30,MEAF6,CREBBP,MCRS1,KAT7,DR1,TAF1,OAS2,KAT8,NAA25,MED24,KAT6A,MDH2,KAT2A,NMT1,ZDHHC12,EP300,ING3,FOXO1,BRD1,ATF2,NAA50,NCOA3,ZDHHC7,LDB1,ZDHHC5,SPI1,MSL3P1,CRTC2,BAG6,NCOA1,NAA11,PCGF2,ZDHHC16,KAT6B,SUPT7L,ZDHHC17,ZDHHC21,ING5,BRCA2,PER1,PPM1B,HCFC1,TADA1,USP22,SUPT3H,POR,ASL,EHHADH,NCOA2,MSL2,OGT,NAA60,ESCO1,PHF20,NAT8
GO:0014911	positive regulation of smooth muscle cell migration	GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION	-0.224533022581405	-0.797891827994795	0.790079461696806	0.936476425158082	30	VTN,RETN,LPAR1,RAPGEF3,DOCK7,PDGFD,PTGER4,F3,BCL2
GO:0032660	regulation of interleukin 17 production	GO_REGULATION_OF_INTERLEUKIN_17_PRODUCTION	0.24470218715993	0.779431371955745	0.790134595201709	0.936476425158082	22	IL2,TNFSF4,TLR4,PRKCQ,IL21,PRNP,IL36RN,FOXP3,TGFB1,LY9,IL15,IL12B
GO:0019373	epoxygenase p450 pathway	GO_EPOXYGENASE_P450_PATHWAY	0.255243327398993	0.770066982463045	0.791057801214327	0.937240605029012	18	CYP2E1,CYP2B6,CYP2F1
NA	male meiosis	GO_MALE_MEIOSIS	-0.217970118889535	-0.804803200374149	0.791696301564723	0.937646288556818	35	KIF18A,CYP26B1,TDRD12,REC8,MOV10L1,TEX14
GO:0046626	regulation of insulin receptor signaling pathway	GO_REGULATION_OF_INSULIN_RECEPTOR_SIGNALING_PATHWAY	-0.211849392475855	-0.811468412661366	0.79261681824291	0.937646288556818	41	TRIM72,PTPN2,SOCS1,MSTN,LEP,INPP5K,OSBPL8,SOCS3,LMBRD1,SIRT1
GO:0009416	response to light stimulus	GO_RESPONSE_TO_LIGHT_STIMULUS	-0.170803847453911	-0.898378913553272	0.79297398062331	0.937646288556818	258	NOC2L,NMU,LRRN4,CNGB1,MAPK10,KDM1A,AQP1,BEST1,POLH,KRAS,GUCY2F,SCARA3,SGK1,PDE6C,CRIP1,HIST3H2A,MEN1,GNAT1,CAT,TP73,GRIN2A,CDKN1A,EGFR,CACNA1F,OPN1LW,HIF1A,TULP1,AIPL1,NETO1,CASP3,GTF2H2,KIAA0101,CHRNB2,YY1,RDH13,MME,CDK5,DDB2,ZBTB1,OPN3,EIF2AK4,DCUN1D3,FBXL21,XPC,IFT20,AURKB,BAX,CACNB4,RS1,CDC25A,TRIAP1,PPP1CA,NPHP1,PITPNM1,MDM2,MYC,JUNB,GUCA1A,ELANE,GNGT1
GO:0003203	endocardial cushion morphogenesis	GO_ENDOCARDIAL_CUSHION_MORPHOGENESIS	0.246088603685701	0.774535642189175	0.79299780373918	0.937646288556818	21	TBX2,TBX20,ENG,SOX9,FGF8,MSX1,TWIST1,HEYL,DCHS1
GO:0090342	regulation of cell aging	GO_REGULATION_OF_CELL_AGING	0.226587486377034	0.793271609677213	0.793065141774872	0.937646288556818	32	HMGA1,FZR1,PTEN,MARCH5,PRKDC,BCL6,TWIST1,NUAK1,CDKN2A,PNPT1,CDK6,YPEL3,BCL2L12,ING2,TERT
GO:0014902	myotube differentiation	GO_MYOTUBE_DIFFERENTIATION	-0.205897092349823	-0.821037456639081	0.793316357572616	0.937646288556818	49	KIAA1161,CDON,RYR1,KCNH1,WNT10B,FER1L5,NPHS1,C16orf89,CAPN2,MYOD1
GO:0016053	organic acid biosynthetic process	GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS	-0.171400090839331	-0.894839990316135	0.793350157400421	0.937646288556818	242	ASS1,PTGIS,SHMT1,LIPC,RDH10,GPT2,ALOX15,GART,UGDH,CARNS1,MTHFD1L,PKLR,ABCB11,XBP1,ALOX12B,TBXAS1,AKR1C3,DECR2,LPL,STAR,PYCR1,CPS1,RBP1,PADI4,AGXT2,PLA2G4F,PSAT1,BCAT1,DHFR,GGT1,GADL1,AGXT,FASN,PTGS1,DCN,OAT,LGSN,PECR,ABAT,PYCR2,CYP7A1,ACSM3,MIF,DEGS1,EDN1,FCER1A,NOXRED1,AGMO,MRI1,HSD3B7,GOT1L1,GPT,NANP,PLA2G4A,DSEL,ACACA,HSD17B12,ACSF3,ACSM1,SRR,ADI1,PADI3,ALOX5AP,CYP8B1,FADS6,VCAN,ALOXE3,CYP46A1,LDHC,PTGES,GGT6
GO:0032675	regulation of interleukin 6 production	GO_REGULATION_OF_INTERLEUKIN_6_PRODUCTION	-0.187644839880203	-0.851132354322975	0.794153846153846	0.938266706266706	95	MAPK13,WNT5A,CEBPB,TBC1D23,XBP1,PYCARD,RIPK2,IL36B,IRAK3,IL17RC,TNFSF9,ORM1,LILRB2,IL17F,HGF,NLRP12,TLR9,ADCYAP1,NOD1,F2R,TLR2,AFAP1L2,CARD9,BANK1,IL10
GO:0051972	regulation of telomerase activity	GO_REGULATION_OF_TELOMERASE_ACTIVITY	0.218101774410958	0.803620029063211	0.794786096256685	0.938684210526316	40	HMBOX1,PARM1,MCRS1,OBFC1,MAP3K4,MAPKAPK5,TCP1,ACD,MAPK1,WRAP53,CCT4,PRKCQ,PKIB,MAP2K7,NEK7,ATM,MAPK3
NA	palate development	GO_PALATE_DEVELOPMENT	-0.190416305042359	-0.84583089374476	0.796754611253794	0.940218441245009	84	C5orf42,OSR1,TGFBR1,WNT5A,MMP25,BBS7,SOX11,SGPL1,SMAD2,DLX6,ASPH,ACVR2B,PAK1IP1,WNT9B,BNC2,PYGO2,DLG1,INHBA,FRAS1,COL11A2,ANP32B,CSRNP1,WNT7A,PKDCC,SNAI2,SATB2,ALX4
GO:0045663	positive regulation of myoblast differentiation	GO_POSITIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION	-0.240064656354903	-0.777200931052575	0.797289334119034	0.940218441245009	21	CDON,TNFSF14,BOC,NEU2,MYOD1
GO:0071900	regulation of protein serine threonine kinase activity	GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	0.169540660718507	0.903473470785622	0.797325924106595	0.940218441245009	445	CCND2,LRP5,MADD,RAPGEF1,TAOK2,PDE5A,CDK5RAP1,MAPKAPK2,PDGFB,TRIB2,TNIK,RGS3,LPAR3,DRD4,LRP6,DVL2,TIAM1,ALS2,FLT1,ZAK,DIRAS2,LRRK2,CALM3,CCND1,MAP3K15,STRADA,TAOK3,WNK1,SASH1,CRKL,ZEB2,ADRA2C,HERC5,MAPKAPK3,HMGCR,PLCE1,PKIA,FGF1,GSK3B,RAPGEF2,JAK2,CAV3,PTEN,CHORDC1,CDK5RAP3,GH1,MAP3K4,PRKAR1A,CD300A,DIRAS1,FZD10,CD40,CDK12,GTPBP4,EZH2,LATS1,LAX1,MAPKAPK5,TGFA,CALM1,RAF1,FGFR1,FBXO31,TNFRSF10B,CCNE2,DBNL,DUSP19,DUSP21,TNF,PIK3R5,CDKN1B,RGS14,MAPK1,CDK1,VEGFA,PKN1,APC,P2RX7,SOD1,HSPB1,TRIB3,GADD45A,CDC25C,DUSP3,EPHA4,MAPK8IP3,MAGED1,MALT1,ADORA2B,PLCG1,CCNL2,MDFI,HYAL2,GRM4,GAB1,DUSP7,HEXIM2,MAP4K2,CARD10,PDE6H,MARCKS,UVRAG,EGF,DIRAS3,PROX1,SLC27A1,NTRK3,TLR4,TGFB3,DUSP4
GO:0001676	long chain fatty acid metabolic process	GO_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS	-0.190098402546236	-0.845939152360332	0.797376604550025	0.940218441245009	85	PTGIS,ACADL,SSTR4,CYP2C9,ALOX15,ACSBG2,ALOX12B,TBXAS1,AKR1C3,DAGLA,ACOT4,LIPE,CYP4F2,PTGS1,CYP1A2
GO:2001269	positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway	GO_POSITIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY	0.257038627737547	0.763587649994748	0.797481773545603	0.940218441245009	17	JAK2,TNFRSF10B,TNFSF10,SMAD3,FASLG
GO:0002820	negative regulation of adaptive immune response	GO_NEGATIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	0.221412525190261	0.796373690063018	0.798294784580499	0.940598178599966	36	XCL1,SPN,CEACAM1,CR1,IL4,LILRB1,BCL6,FOXJ1,TNFSF4,JAK3,SUSD4,FOXP3,PPP3CB,RC3H1
GO:0010591	regulation of lamellipodium assembly	GO_REGULATION_OF_LAMELLIPODIUM_ASSEMBLY	0.236790832077091	0.77958709854981	0.798407076397937	0.940598178599966	25	SSH2,HDAC4,CAPZB,MTOR,SSH1,PLXNB3
GO:0010812	negative regulation of cell substrate adhesion	GO_NEGATIVE_REGULATION_OF_CELL_SUBSTRATE_ADHESION	-0.205168980350487	-0.818134029411137	0.798837235504879	0.940598178599966	49	HOXA7,SPOCK1,EFNA5,ADAM15,ITGB1BP1,MEN1,CORO1C,SEMA3E,THBS1,CASK,MUC21
GO:0046640	regulation of alpha beta t cell proliferation	GO_REGULATION_OF_ALPHA_BETA_T_CELL_PROLIFERATION	-0.235020260758935	-0.779520755664764	0.799209833187006	0.940598178599966	23	CD55,IL18,RIPK2
GO:0043516	regulation of dna damage response signal transduction by p53 class mediator	GO_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	-0.231376418352245	-0.784857683528159	0.799542967634198	0.940598178599966	25	KDM1A,PSMD10,MDM2,MIF,SIRT1,SNAI2,SPRED2,PMAIP1,CD44,HIC1,ZNF385A,CD74,ANKRD1,PLA2R1,SPRED1,PTTG1IP,SNAI1,SENP2,ATR,SMYD2,ATM,CDKN2A,DYRK1A,TWIST1,MSX1
GO:0006491	n glycan processing	GO_N_GLYCAN_PROCESSING	0.250101771605332	0.765340760099389	0.799959232080646	0.940598178599966	19	MGAT4B,EDEM2,MGAT4C,GNPTAB,MAN2A2
GO:0048536	spleen development	GO_SPLEEN_DEVELOPMENT	0.222011817124576	0.793238366692243	0.800054535538993	0.940598178599966	35	JARID2,RC3H2,PCID2,TET2,TCF21,FLVCR1,NKX2-5,PKN1,PSMB9,PRKDC
GO:0071622	regulation of granulocyte chemotaxis	GO_REGULATION_OF_GRANULOCYTE_CHEMOTAXIS	0.219831099486876	0.796241645515015	0.800170175787968	0.940598178599966	37	C1QBP,XCL1,LBP,CXCL2,DAPK2,CX3CL1,IL4,S100A7
GO:0044058	regulation of digestive system process	GO_REGULATION_OF_DIGESTIVE_SYSTEM_PROCESS	-0.217546626787834	-0.797393571553926	0.80055967663128	0.940598178599966	34	APOA2,AQP1,SGK1,TACR1,LEP,NR1H3,WNK3,PAWR,TAC4,FGF10,STK39,NEUROD1
GO:0035710	cd4 positive alpha beta t cell activation	GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.225138057393605	0.788197230322986	0.800641037314928	0.940598178599966	32	RC3H2,RSAD2,ATP7A,IL18R1,IL4,HMGB1,TNFSF4,SATB1
GO:0060538	skeletal muscle organ development	GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT	0.185950889577082	0.850899169059442	0.801045343469997	0.940598178599966	125	XK,SRPK3,DNER,CFLAR,ANKRD2,GTF3C5,MSC,TAZ,HLX,SVIL,BCL9L,HIVEP3,PLAGL1,DMD,ZNF689,SMYD1,KLHL31,SIX1,EP300,TCF21,EMD,NCOR1,HOMER1,MEF2D,CNTFR,LEMD2,FLNB,GPCPD1,HOXD10,VGLL2,NR2F2,MEF2C,MAFF,P2RX2,SAP30,SMO,IGFBP5,PHOX2B,ANKRD33
GO:0008589	regulation of smoothened signaling pathway	GO_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY	-0.198209298381321	-0.824982565759253	0.801157153311379	0.940598178599966	60	TRAF3IP1,GAS1,WNT9A,RFX4,FGFR2,FOXA1,OTX2,KIF7,KCTD11,FGF9
GO:0043407	negative regulation of map kinase activity	GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY	-0.1946903760179	-0.832944508818668	0.801508177002614	0.940682191000976	69	DUSP18,MAPK8IP1,BMP4,SFRP2,RGS4,TP73,ADIPOQ,IRAK3,SORL1,INPP5K,ZNF675,DUSP2,RGS2,DUSP22,UCHL1,PTPN5,DUSP1,APOE,GBA,SPRED2,PTPN6,BMP7,SPRY1
NA	positive regulation of multicellular organismal metabolic process	GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_METABOLIC_PROCESS	-0.241214385005235	-0.770815667586566	0.802358470040468	0.941129212921151	20	BMP4,RETN,CTGF,F2
GO:0021680	cerebellar purkinje cell layer development	GO_CEREBELLAR_PURKINJE_CELL_LAYER_DEVELOPMENT	0.237903844706151	0.775216332314135	0.802448259383156	0.941129212921151	24	HERC1,ATP7A,RERE,LDB1,LHX1,UQCRQ,KLHL1,AGTPBP1
GO:0006487	protein n linked glycosylation	GO_PROTEIN_N_LINKED_GLYCOSYLATION	-0.19389912259112	-0.832242836448634	0.803280203280203	0.941776790052652	70	GAL3ST1,MAN1C1,MGAT5B,PGM3,DAD1,RPN1,MGAT3,FUT8,B4GALT7,MAN1A1,DPAGT1,MGAT2,ST3GAL5,DOLPP1
GO:1903019	negative regulation of glycoprotein metabolic process	GO_NEGATIVE_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS	0.2621653778272	0.753323686476785	0.803788174501385	0.941898149061899	15	ACER2,ACOT8,AATF,PTX3,APCS,JAK3,CST3
GO:1902170	cellular response to reactive nitrogen species	GO_CELLULAR_RESPONSE_TO_REACTIVE_NITROGEN_SPECIES	0.249123126745073	0.762345992023936	0.803943369653843	0.941898149061899	19	GUCY1B3,MTR,FOXO1,TPO,AIFM1,MT3,PPARGC1A,DNM2
GO:0007271	synaptic transmission cholinergic	GO_SYNAPTIC_TRANSMISSION_CHOLINERGIC	-0.219162259656552	-0.791448446961805	0.804883457896254	0.942671440250102	32	HTR3A,ZACN,HRH4,CHRNB2,NQO1,CHRNG,CHRM4
GO:0036465	synaptic vesicle recycling	GO_SYNAPTIC_VESICLE_RECYCLING	-0.23541091749217	-0.771783199576986	0.805891751110722	0.943215935761847	22	SNCA,CANX,CDK5,SYT5,SYT1,PLD2,SH3GL2,WNT7A,ITSN1
GO:0032770	positive regulation of monooxygenase activity	GO_POSITIVE_REGULATION_OF_MONOOXYGENASE_ACTIVITY	0.232943552755122	0.774587144944044	0.806083719906856	0.943215935761847	26	CALM3,ESR1,AGTR2,CALM1,TNF,PARK7
GO:0003158	endothelium development	GO_ENDOTHELIUM_DEVELOPMENT	0.19384350137469	0.830670196299838	0.806352978176926	0.943215935761847	85	RAPGEF1,NRP1,CSNK2B,PPP1R16B,RAPGEF6,BMPER,GJA1,RAPGEF2,RAB1B,STARD13,PDE2A,DLL4,RAP2C,GJA5,COL18A1,S1PR1,SOX17,ENG,HEY2,RDX
GO:0090312	positive regulation of protein deacetylation	GO_POSITIVE_REGULATION_OF_PROTEIN_DEACETYLATION	0.251248949040604	0.75801597638737	0.807304528659227	0.943215935761847	18	AKAP8,BRMS1,VEGFA,BCL6,AKAP8L,DYRK1A,C6orf89,TGFB1,SREBF1,PRKD2,NIPBL,CTBP1
GO:0060632	regulation of microtubule based movement	GO_REGULATION_OF_MICROTUBULE_BASED_MOVEMENT	-0.251082041146587	-0.754438351845785	0.807758079528974	0.943215935761847	16	HAP1
GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	0.229392458143754	0.777280420298423	0.807808356953461	0.943215935761847	28	CRIPAK,KANK2,CYP7B1,ZNF366,TCF21,CNOT1,PER1,NR0B1,HEYL,CRY2,FOXP1,STRN3
GO:1903305	regulation of regulated secretory pathway	GO_REGULATION_OF_REGULATED_SECRETORY_PATHWAY	0.185554452122936	0.846575423800364	0.808278162601903	0.943215935761847	123	C2CD4A,SPINK8,UNC13D,SYT9,ZP2,SYT8,LRRK2,SYTL2,VAMP2,CEACAM1,ABR,STX1A,ARF1,SYT7,REST,RAB3GAP1,CD300A,GRIK5,STX4,CCR2,IL4,SYT12,SYTL3,RPH3AL,ADORA2B,PTAFR,ZP3,C2CD4B,ATP2A2,PFN2,RAB3A,RIMS3,DOC2B,SYTL4,TMEM27,AP1G1
GO:0060384	innervation	GO_INNERVATION	-0.232971912657509	-0.772726746268587	0.808318700614574	0.943215935761847	23	SULF1,SEMA3A,SULF2,UNC13B,RET,GABRB2,ISL1
GO:0019985	translesion synthesis	GO_TRANSLESION_SYNTHESIS	-0.215033019206224	-0.793958653254621	0.808477062588905	0.943215935761847	35	RPA3,POLH,UBA52,RPA2,KIAA0101,ZBTB1,UBB,PCNA,POLE2,POLD1,RFC1,RPS27A,RCHY1,RFC4,RFC2
GO:0006282	regulation of dna repair	GO_REGULATION_OF_DNA_REPAIR	-0.195599579129078	-0.824116556504067	0.808830642375106	0.943215935761847	64	KDM1A,FOXM1,POLH,FIGNL1,KDM4D,EGFR,RPA2,CEBPG,RPS3,WHSC1,BRCC3,SIRT6,POLQ,RNF8,SIRT1,PCNA,USP1,HELB,UBE2V2
NA	positive regulation of g protein coupled receptor protein signaling pathway	GO_POSITIVE_REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY	-0.232805014817208	-0.772173175567192	0.809108867427568	0.943215935761847	23	C3,PRMT5,F2,KLK5
GO:0015909	long chain fatty acid transport	GO_LONG_CHAIN_FATTY_ACID_TRANSPORT	0.215577894497753	0.794320515317024	0.809528110998699	0.943215935761847	40	SLC27A5,DRD4,DRD2,PRKAB2,PLA2G5,PRKAA2,SLC27A6,FABP3,NMUR2,ACACB,CD36
GO:0006517	protein deglycosylation	GO_PROTEIN_DEGLYCOSYLATION	0.242162374060936	0.76217828496802	0.809792739420113	0.943215935761847	21	EDEM2,MGEA5,SEL1L,PARK7,MAN2A2,MAN2C1,UGGT1,SYVN1
GO:0070286	axonemal dynein complex assembly	GO_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY	0.260434194817395	0.748349188403391	0.809884942099296	0.943215935761847	15	DNAI2,ZMYND10,DNAI1,SPAG1
GO:0051495	positive regulation of cytoskeleton organization	GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION	-0.175671152955243	-0.870617165888124	0.810071045743487	0.943215935761847	165	ARHGEF5,WASF1,S100A10,KATNB1,CTGF,BAIAP2L2,ALOX15,LPAR1,ITGB1BP1,ARPC5,TACR1,EVL,ACTR3,KIRREL,NPHS1,PYCARD,CCL21,WHAMM,BAIAP2,CCNB1,CDK5,RPS3,TPM1,CDC42EP1,SCIN,RAPGEF3,PPM1E
GO:0051156	glucose 6 phosphate metabolic process	GO_GLUCOSE_6_PHOSPHATE_METABOLIC_PROCESS	-0.237133933931227	-0.767712819679071	0.810297038346537	0.943215935761847	21	PGLS,HK2,H6PD,G6PC,PGM2,TPI1,RPE
GO:0030168	platelet activation	GO_PLATELET_ACTIVATION	0.183259437802937	0.850517754729812	0.810900738088402	0.943215935761847	138	P2RY1,GNAS,GNA12,PIK3R1,VWF,ITPR1,MYL12A,ITGB3,GNG2,ADRA2C,DGKQ,F8,PRKCH,CD40,CX3CL1,RAF1,MYL9,ITGA2B,DGKZ,PIK3R5,FZD6,MAPK1,DGKE
GO:0035082	axoneme assembly	GO_AXONEME_ASSEMBLY	-0.21813933493859	-0.787754415970072	0.811048768046839	0.943215935761847	32	C11orf63,CCDC114,TTLL1,DNAH1,SPEF2,RP1L1,DNAH5,LRRC6
NA	regulation of cgmp metabolic process	GO_REGULATION_OF_CGMP_METABOLIC_PROCESS	-0.221626024516885	-0.780956662144582	0.811367908879796	0.943215935761847	29	NPR1,WNT5A,OSTN,AIPL1,THBS1,GUCA1A,HPCA,PTK2B,GUCA2A,APOE,PDZD3,RCVRN
GO:0031579	membrane raft organization	GO_MEMBRANE_RAFT_ORGANIZATION	0.253529160467129	0.753162034633589	0.811374795417349	0.943215935761847	17	PACSIN2,CAV3,MAL,NPC1,FLOT1,EMP2
GO:0050996	positive regulation of lipid catabolic process	GO_POSITIVE_REGULATION_OF_LIPID_CATABOLIC_PROCESS	0.235879383266927	0.768619568088803	0.811436238650149	0.943215935761847	24	AKT2,ADRB2,PPARA,IRS1,PRKCE,APOA5,TWIST1,PNPLA2
GO:0043029	t cell homeostasis	GO_T_CELL_HOMEOSTASIS	0.222915912482215	0.780417610631804	0.811513175866402	0.943215935761847	32	RC3H2,STAT5B,SLC39A3,ZC3H8,SLC46A2,DNAJA3,P2RX7,FOXN1,JAK3,GPR174,FOXP3,PPP3CB,RC3H1
GO:0044068	modulation by symbiont of host cellular process	GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS	0.233727543489018	0.769501825224621	0.81239103705199	0.943502005411499	25	BAD,CCR2,KPNA4,KPNA3,VAPB,NTRK3,CD4,KPNB1
GO:0043901	negative regulation of multi organism process	GO_NEGATIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS	-0.178578485808972	-0.862753048197731	0.812647001176009	0.943502005411499	139	IFITM2,TIMP1,SLPI,CCL3,TARBP2,TRAF3IP1,TRIM11,HTRA1,BTBD17,MID2,TRIM62,APOBEC3F,ACVR1C,FCN3,TRIM35,TRIM38,EIF2AK4,MBL2,ASTL,INPP5K,DEFB114,CCL4,IL2RA,NODAL,GPR149,ELANE,IFI16,TRIB1
GO:0045661	regulation of myoblast differentiation	GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION	0.210506519087292	0.796215136254969	0.812703495170081	0.943502005411499	45	PPARD,ANKRD2,PRICKLE1,IGFBP3,CAPN3,ZFHX3,SMYD1,TNF,SOX9,CXCL9,TBX3,GDF3,MEF2C
GO:2001020	regulation of response to dna damage stimulus	GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	-0.180672136391524	-0.857653897587553	0.813190826313483	0.943502005411499	125	TAF9B,KDM1A,FOXM1,SFRP2,POLH,MUC1,SKIL,FIGNL1,KDM4D,EGFR,RPA2,TPT1,CEBPG,RPS3,WHSC1,BRCC3,PSMD10,CHEK2,SIRT6,POLQ,RNF8,TRIAP1,BRD4,MDM2,MIF,MYC,ABL1,SIRT1,PCNA,USP1,HELB,UBE2V2
GO:0045940	positive regulation of steroid metabolic process	GO_POSITIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS	-0.233769036130539	-0.766400371694134	0.81342058611105	0.943502005411499	22	APOA2,APOC1,AGTR1
GO:0002833	positive regulation of response to biotic stimulus	GO_POSITIVE_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS	-0.215448334050446	-0.789702507046346	0.813441122906765	0.943502005411499	34	PRKCA,KLK7,LY96,RIPK2,KLK5,NOD1,MIF
GO:0098927	vesicle mediated transport between endosomal compartments	GO_VESICLE_MEDIATED_TRANSPORT_BETWEEN_ENDOSOMAL_COMPARTMENTS	-0.238596810921121	-0.762451045737584	0.813933249205866	0.943747611721304	20	MYO1D,SNF8,SNX16,HOOK2
GO:1901016	regulation of potassium ion transmembrane transporter activity	GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.21476347298476	0.791319689479141	0.814460182107241	0.944033392897029	40	ANK2,NEDD4L,RNF207,VAMP2,AKAP6,CAV3,KCNRG,ANK3,SUMO1,ATP1B2,CASQ2,ACTN2,DNM2,KCNAB1,KCNQ1,CAB39,FHL1
GO:0023014	signal transduction by protein phosphorylation	GO_SIGNAL_TRANSDUCTION_BY_PROTEIN_PHOSPHORYLATION	-0.16496604670015	-0.90713635730872	0.814936970679487	0.944260875492996	384	KCNH5,TYRO3,SCG2,MAPK8IP1,CCL3,EPGN,TNFSF11,CCL19,MAPK10,AMHR2,MAPK13,KDR,IL18,FGF22,IRAK4,TGFBR1,WNT5A,NRG4,MAP2K4,KLB,FGF7,ANGPT1,KRAS,FGFR2,MAP2K2,KCNH1,MAPK12,MDFIC,FGF17,ACVR1,SPTBN4,MAP3K8,IRAK1,MEN1,DOK4,FGF18,BMPR1B,GRIN2A,NPHS1,RIPK2,RIPK1,EGFR,CHUK,ACVR1C,ARTN,FGF4,UBA52,PSPN,STK3,IKBKG,PSMB11,FGF13,FGF9,PAK3,GDNF,LAT,PSMD10,IL5,MAP3K11,NOD1,GRIN2D,SPTBN2,ACVR2B,RASA3,ACVR1B,CUL1,PSMD5,IL2RA,PSMD13,PSMB5,MYC,SHC3,FGFR4,FCER1A,MAP3K2,POU4F2,SPTAN1,MAPK11,PTGER4,UBB,TRIB1,MOS
GO:0050869	negative regulation of b cell activation	GO_NEGATIVE_REGULATION_OF_B_CELL_ACTIVATION	0.229311838004225	0.76968799264373	0.815431386553852	0.944508619112274	27	CTLA4,INPP5D,CD300A,SLA2,PKN1,BCL6,FOXJ1,FOXP3,CDKN2A,RC3H1,ATM,TNFAIP3
GO:1902882	regulation of response to oxidative stress	GO_REGULATION_OF_RESPONSE_TO_OXIDATIVE_STRESS	0.201791389734056	0.807559327602988	0.816093794477654	0.944721980655424	59	TRAP1,FBXW7,LRRK2,PINK1,FBLN5,TNF,SOD2,PARK7,HDAC6,SOD1,HSPB1,SFPQ,NME5,CD36,ENDOG
GO:0006903	vesicle targeting	GO_VESICLE_TARGETING	-0.191454108646876	-0.826141395339107	0.816506540108809	0.944721980655424	72	NLGN1,TMED10,AREG,SCFD1,TMED2,ANKRD28,SEC24D,SNAP23,SEC24A,SEC13,COL7A1,F5,SEC31A,TMED9,PSEN1,CNIH2,LMAN1,MCFD2,NSF
GO:2000050	regulation of non canonical wnt signaling pathway	GO_REGULATION_OF_NON_CANONICAL_WNT_SIGNALING_PATHWAY	-0.24579057257665	-0.751702347176843	0.816563567937016	0.944721980655424	17	WNT5A,SFRP2,DAB2,NKD1,ABL1
GO:0032695	negative regulation of interleukin 12 production	GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION	0.258402209580345	0.742510344913346	0.817041208944404	0.944721980655424	15	C1QBP,MEFV,NFKB1,LILRB1,JAK3
GO:0050954	sensory perception of mechanical stimulus	GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS	-0.177388178887852	-0.860631471943516	0.81747806640289	0.944721980655424	143	RPL38,TMPRSS3,PDZD7,MYO15A,ATP6V1B1,CEACAM16,LRTOMT,PIEZO2,GRXCR1,TIMM10,MARVELD2,TIMM9,ZNF354A,SPTBN4,ATP2B2,DFNA5,USH1G,EML2,CASP3,CHRNB2,FAM107B,TMC2,KCNA1,KCNQ4,MYO3A
GO:0044788	modulation by host of viral process	GO_MODULATION_BY_HOST_OF_VIRAL_PROCESS	-0.245491739016723	-0.750788423237215	0.817580135830774	0.944721980655424	17	PPIB,PC,EIF2AK4
NA	cell separation after cytokinesis	GO_CELL_SEPARATION_AFTER_CYTOKINESIS	0.258222109513618	0.741992833229212	0.817580252421049	0.944721980655424	15	VPS4A,CHMP7,MITD1,CHMP6,CHMP1B,CHMP4B,CHMP4C
GO:0018196	peptidyl asparagine modification	GO_PEPTIDYL_ASPARAGINE_MODIFICATION	0.217853521611359	0.783572712292488	0.817922902494331	0.944729731780992	36	ST6GALNAC4,ST3GAL6,ST3GAL3,ST3GAL2,DERL3,ST6GALNAC3,NUDT14,VCP,ST6GAL1,DPM2,ST3GAL4,SYVN1
GO:0007015	actin filament organization	GO_ACTIN_FILAMENT_ORGANIZATION	0.180578575057325	0.853395412810179	0.818148297130598	0.944729731780992	157	MSRB2,FRY,MICAL3,FRYL,ARHGEF2,GHSR,ARAP1,LMOD1,LMOD3,CTNNA1,ARF1,INPPL1,ADD1,JAK2,CAV3,SPIRE1,TCAP,CFL1,ACTR3B,PPP1R9A,TTN,RHOF,WASL,TMOD1,JMY,FHOD3,PHACTR1,ALDOA,TNNT2
GO:0032715	negative regulation of interleukin 6 production	GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION	-0.219062959531022	-0.778453624400781	0.819141636601076	0.945307576948814	30	IRAK3,ORM1,HGF,NLRP12,TLR9,BANK1,IL10,KLF2,GAS6,GBA
GO:0045071	negative regulation of viral genome replication	GO_NEGATIVE_REGULATION_OF_VIRAL_GENOME_REPLICATION	0.21029929324315	0.791653211947312	0.819396668167492	0.945307576948814	44	ADAR,RSAD2,IFIT1,OASL,OAS3,OAS1,TNF,APOBEC3D,APOBEC3H,VAPB,PROX1
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	GO_NEGATIVE_REGULATION_OF_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	0.251526363494692	0.747212302303236	0.819725487278679	0.945307576948814	17	MCRS1,ACD,HNRNPU,NAT10,TNKS,HNRNPC,GNL3L,PARP1,TNKS2
GO:0007422	peripheral nervous system development	GO_PERIPHERAL_NERVOUS_SYSTEM_DEVELOPMENT	0.200289111031014	0.807134517127511	0.819772078762207	0.945307576948814	61	LAMA2,AKT2,SH3TC2,HAND2,LAMB2,OSM,MED12,NFASC,RUNX3,SOD1,DICER1,GPC1
GO:0051640	organelle localization	GO_ORGANELLE_LOCALIZATION	0.169506255778506	0.889448682586124	0.820883196210421	0.945922397237783	378	C2CD4A,RHOT2,NDE1,FYCO1,MARK2,SPAG5,CPLX1,SYT9,MREG,NRXN1,CLASP1,KIF13A,MFN2,CENPA,SEC24C,PAFAH1B1,RAB6A,SYT8,VPS4A,LRRK2,SYNDIG1,CPLX3,KIF5B,STON2,TRAPPC9,SYTL2,ARHGEF2,VAMP2,GOLGA2,F8,EYA1,STX1A,ARF1,DYNC1H1,SYT7,PEX14,RAB1B,CAV3,CHMP7,SPIRE1,RAD21L1,GRIA1,NIN,AP1M2,CADPS,GPSM2,KAT2A,GORASP1,NMD3,TGFA,LAT2,SPO11,FAM83D,SLC4A5,STX4,MAP4,PRKCZ,WASL,FNBP1L,KIFC1,OPHN1,TMEM201,SYT12,HDAC6,PPP6R1,ARHGAP21,SYTL3,P2RX7,DCTN1,PAX6,DLGAP5,SYNE2,RPH3AL,MAP1S,TRAPPC5,MKKS,AP3M2,PIP5K1C,HTT,ATP6AP1,GBF1,C2CD4B,MAP4K2,S100A13
NA	regulation of symbiosis encompassing mutualism through parasitism	GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM	-0.173297377021179	-0.872312409304293	0.821012262199122	0.945922397237783	184	IFITM2,PPIB,SLPI,CCL3,TARBP2,POLR2H,SNW1,TRIM11,MDFIC,PC,BTBD17,MID2,VPS25,TRIM62,PABPC1,APOBEC3F,POLR2K,SNF8,FCN3,TOP2A,TRIM35,TRIM38,PPIH,TMPRSS2,EIF2AK4,MBL2,HS3ST5,GTF2F1,INPP5K
GO:0010544	negative regulation of platelet activation	GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION	0.250792417031922	0.745031958984172	0.822087486981104	0.945922397237783	17	PDGFB,ADRB2
GO:0032655	regulation of interleukin 12 production	GO_REGULATION_OF_INTERLEUKIN_12_PRODUCTION	0.204688033153951	0.795532861272975	0.822120376669412	0.945922397237783	51	C1QBP,HSPD1,CD40,IDO1,HLA-B,MEFV,IRF1,NFKB1,HMGB1,CD36,LILRB1,TNFSF4,TLR4,MAST2,JAK3,IRF8
GO:0002260	lymphocyte homeostasis	GO_LYMPHOCYTE_HOMEOSTASIS	-0.202761018072883	-0.801046258629921	0.822141601694533	0.945922397237783	47	TNFSF14,SKIL,CACNA1F,HIF1A,RIPK3,CASP3,RAG1,LAT,FAS,BAX,IL2RA,SPNS2,RPS6,ABL1,BCL2,TNFRSF13C,TNFRSF17
NA	regulation of protein phosphatase type 2a activity	GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY	0.234757855855555	0.756917702812928	0.822306307630138	0.945922397237783	23	PPP2R5C,PPP2R3A,PPME1,HTT,PPP2R2B,PPP2R5B,PPP2R1A,PPP2R5E,EIF2AK2,ARPP19
NA	monosaccharide transport	GO_MONOSACCHARIDE_TRANSPORT	0.204616335359641	0.79525420330467	0.822550037595331	0.945922397237783	51	SLC2A12,PPARD,TSC1,SLC5A1,KLF15,GH1,GCK,SLC26A5,SLC2A4,HK3,SORT1,PRKAG3,SLC2A6,SLC2A14,SORBS1,SLC23A1
GO:0060412	ventricular septum morphogenesis	GO_VENTRICULAR_SEPTUM_MORPHOGENESIS	-0.224629675107613	-0.769922434937211	0.822888942656666	0.945922397237783	26	WNT5A,FGFR2,SOX11
GO:0034470	ncrna processing	GO_NCRNA_PROCESSING	-0.165766604772876	-0.898497891677851	0.823195059299339	0.945922397237783	335	RPL24,RPL38,TARBP2,RBFA,RPL35,RPL30,RPL9,RPL3,RPS3A,RPS19,XRN2,RPS27,RPL4,RPS11,RPL7A,TPRKB,RPS4Y1,WDR75,WDR46,RPS8,FARS2,MOCS3,RPL18,NOC4L,EXOSC2,NOP10,TP53RK,EXOSC6,RPS24,RPL18A,UBA52,TRIT1,RPL15,RPS16,WDR43,INTS10,RPP25,PRKRA,SMAD2,RPL5,RPS27L,EXOSC5,NSA2,RPL10A,RPS3,TRMT61A,RPL22,RPS29,RPL26,RPL19,KRR1,CTU2,SART1,HSD17B10,EXOSC10,RPS28,RPS5,FTSJ1,RPS17,MTO1,DROSHA,EXOSC8,WDR36,PES1,DHX37,NHP2,RPF2,POP1,DDX21,PAPD5,RPL36,TRMT11,RPS6,DDX51,RPP21,SIRT1,TYW1B,MTFMT,RPL23A,RPP30,RPS18,FAU,RPL32,BOP1,RPLP0,RPL14,NOP14,RPS15,GTPBP3,RRP36,RIOK3,PNO1,RPS13,THUMPD1,RPL28,RPS4X,RPL34,NOL11,LAS1L,TSEN54,NOLC1,PUS7,RPL27,RRS1,DIMT1
GO:0090130	tissue migration	GO_TISSUE_MIGRATION	-0.189252309374626	-0.826937822218235	0.823223046339138	0.945922397237783	77	SCG2,DPP4,KDR,TGFBR1,T,FAP,GRHL2,FOXF1
GO:0007031	peroxisome organization	GO_PEROXISOME_ORGANIZATION	0.219673032611213	0.774434155855819	0.823396501457726	0.945922397237783	33	PEX14,LONP2,PEX7,ACOT8,PEX26,PEX12,SCP2,ACBD5,PEX3,PEX19,PEX13,PEX6,PEX2
GO:0072525	pyridine containing compound biosynthetic process	GO_PYRIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	-0.241404728085029	-0.749671246109643	0.823989598006285	0.946046774049737	18	NADK,PSAT1,NAMPT,NADSYN1
GO:0016444	somatic cell dna recombination	GO_SOMATIC_CELL_DNA_RECOMBINATION	-0.215756363337084	-0.779148923509273	0.824066886961921	0.946046774049737	32	TCF3,RAG2,EXOSC6,RAG1,MSH3,HMGB2,RNF8,NBN,SWAP70
GO:0048538	thymus development	GO_THYMUS_DEVELOPMENT	0.209880872390922	0.78622224618454	0.825466006303467	0.947329893357473	43	JARID2,HAND2,CRKL,TYR,SLC46A2,SIX1,SHH,RAF1,MAPK1,SOD1,PSMB9,PRKDC,MAD1L1,FOXN1,SRF
GO:0070884	regulation of calcineurin nfat signaling cascade	GO_REGULATION_OF_CALCINEURIN_NFAT_SIGNALING_CASCADE	0.253142483390221	0.739665888363936	0.826298671127219	0.947900482578898	16	RCAN2,AKAP6,PRNP,SPPL3,NFAT5,CHP2,ERBB3
GO:0033599	regulation of mammary gland epithelial cell proliferation	GO_REGULATION_OF_MAMMARY_GLAND_EPITHELIAL_CELL_PROLIFERATION	-0.250568298468633	-0.73816599614598	0.826526416033591	0.947900482578898	15	GATA3,BAX,ZNF703,PYGO2,GPX1,PHB2,ETV4
GO:0071479	cellular response to ionizing radiation	GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION	-0.201823445230269	-0.797342197440512	0.827797557348236	0.948727488544175	47	KDM1A,SFRP2,SWI5,FIGNL1,KDM4D,CDKN1A
GO:0006855	drug transmembrane transport	GO_DRUG_TRANSMEMBRANE_TRANSPORT	0.242948081996493	0.743449630709934	0.828163219924394	0.948727488544175	19	SLC17A3,ABCA8,ABCC2,ABCB4,ATP8B1,ABCG2
GO:0032801	receptor catabolic process	GO_RECEPTOR_CATABOLIC_PROCESS	-0.245886346934774	-0.738826598173739	0.828257246141524	0.948727488544175	16	SNX25,SH3GLB1,CDK5,CAPN1
GO:0038034	signal transduction in absence of ligand	GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND	0.22221614696183	0.765863187545383	0.828374952118636	0.948727488544175	30	BAD,MOAP1,BAG3,GSK3B,IL4,IL2,BAK1,CASP2,CASP9,BCL2A1
GO:0001953	negative regulation of cell matrix adhesion	GO_NEGATIVE_REGULATION_OF_CELL_MATRIX_ADHESION	-0.221669051062708	-0.767438763607528	0.828740721161259	0.948823560349931	27	HOXA7,ADAM15,ITGB1BP1,CORO1C,SEMA3E,THBS1,CASK,MMP14,RCC2
GO:0034453	microtubule anchoring	GO_MICROTUBULE_ANCHORING	0.248739994981906	0.738934804856936	0.829936021425383	0.948862803370419	17	CLASP1,PEX14,NIN,CEP57L1
GO:0072529	pyrimidine containing compound catabolic process	GO_PYRIMIDINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS	-0.218032978571957	-0.768295634748546	0.830012164104832	0.948862803370419	29	DPYS,DUT,APOBEC3F,SMUG1,NEIL2,NT5M
GO:0045921	positive regulation of exocytosis	GO_POSITIVE_REGULATION_OF_EXOCYTOSIS	-0.18699411797624	-0.826601790008096	0.830394469486419	0.948862803370419	82	ATP13A2,CFTR,SMPD3,NLGN1,RAB27B,SDC1,IQCF1,SNF8,CDK5,VAMP8,CACNA1I,UNC13B,KCNB1,STXBP1
GO:0070371	erk1 and erk2 cascade	GO_ERK1_AND_ERK2_CASCADE	0.234776722766945	0.747816540805643	0.830513155714312	0.948862803370419	22	AGT,CTSH,MAPK1,SOX9,EGF,MED1,MT3
GO:0002831	regulation of response to biotic stimulus	GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS	-0.170232720672921	-0.876396275858384	0.83064619815372	0.948862803370419	217	PRKCA,CD55,SNRPB2,TARBP2,TRAF3IP1,CPA3,TRAF3IP2,ALPK1,KLK7,LENG9,FGF7,HTRA1,LY96,ANXA5,IL27,MB21D1,TMEM39A,ATP6V1H,RIPK2,APOBEC3F,HCAR1,FGFBP1,UBA52,MSTN,PHYHIP,AP1S3,ZCCHC17,HPR,TRIM38,SLC25A19,LMCD1,EIF2AK4,KLK5,YIPF1,HIST1H3C,FABP1
GO:0051057	positive regulation of small gtpase mediated signal transduction	GO_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	0.215228660930243	0.774131647543664	0.830730158730159	0.948862803370419	36	MCF2L,ALS2,RASGRF1,RASGEF1A,AKAP13
GO:0022400	regulation of rhodopsin mediated signaling pathway	GO_REGULATION_OF_RHODOPSIN_MEDIATED_SIGNALING_PATHWAY	0.225907295505183	0.758260604050258	0.830760214640221	0.948862803370419	27	RHO,CALM3,GUCA1C,NMT1,CALM1,CAMKMT,GRK4,METAP1,PPEF1,METAP2
GO:0002712	regulation of b cell mediated immunity	GO_REGULATION_OF_B_CELL_MEDIATED_IMMUNITY	0.213308805312748	0.77741793189555	0.831044700610704	0.948862803370419	38	UNG,XCL1,CD40,CR1,IL4,TNF,EXOSC3,IL2,BTK,BCL6,FOXJ1,TNFSF4
GO:0008088	axo dendritic transport	GO_AXO_DENDRITIC_TRANSPORT	-0.216565969751941	-0.76958041850701	0.831647446822639	0.948862803370419	30	HAP1,AP3M1,KLC3,HIF1A,AP3S1,KIF4A,SNAPIN,SPAST,BLOC1S3,UCHL1
GO:0060249	anatomical structure homeostasis	GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS	-0.168428637733626	-0.882740280151988	0.831755413746208	0.948862803370419	250	SERPINA3,MUC2,RBP4,TYRO3,SLC28A3,AZGP1,TNFSF11,CNGB1,CD7,IQCB1,ILDR2,POTEE,CTGF,RPA3,FGF7,KRAS,HIST1H4C,GAA,ACTG1,MUC6,CTNNB1,USH1G,SLC17A7,CSF1,PRLH,NOP10,HIF1A,TULP1,PRDM14,AIPL1,MSTN,RPA2,CDH3,HIST1H4D,DCLRE1B,PIGR,CTSK,MTM1,ZNF675,HIST1H4E,TLR9,CD34,BAX,IGKC,BARD1,F2R,RP1L1,WDR36,NHP2,BBS10,NBN,IL20RB,XRCC5,NELL2,PCNA,CST4,POLE2,BCL2,POTEF,PLA2G4A,LYZ,CYTL1,ACACA,RAC1,TERF1,GPR55,TINF2,KLHL10
GO:0050770	regulation of axonogenesis	GO_REGULATION_OF_AXONOGENESIS	-0.174078732785316	-0.859633650168285	0.832086677766457	0.948862803370419	161	SEMA3F,SEMA3C,NKX6-1,WNT5A,ULK2,FMOD,MAP2K2,EFNA5,SKIL,RTN4,SEMA3A,SEMA3B,POU3F2,PLXNB2,PLXNA2,SLIT3,ROBO2,EPYC,MAG,SEMA3D,CDK5,RND2,FGF13,CDH4,SEMA3E,SEMA4B,NRCAM,SSH3,RHOA,SEMA4A,FSTL4,WDR36,PLXNA4,PLXNB1,TTL,ABL1,PSEN1,RET,RNF6,RAB11A,NRG1,WNT3,WNT7A,PLXNA1,CRABP2,SEMA7A,SPP1
GO:0021675	nerve development	GO_NERVE_DEVELOPMENT	-0.191850290498309	-0.812884166202033	0.832173007979646	0.948862803370419	66	SEMA3F,SULF1,HOXA3,LPAR1,SEMA3A,CTNNB1,SULF2,CHRNB2,UNC13B
NA	nuclear transcribed mrna poly a tail shortening	GO_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING	-0.229286205879737	-0.751703631581221	0.832439648946182	0.948862803370419	22	CNOT6,EIF4A2,PABPC1,PARN
GO:0002819	regulation of adaptive immune response	GO_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	0.183434112099832	0.832943064704795	0.833197251139688	0.948864204293128	119	TRPM4,RSAD2,UNG,HLX,XCL1,SPN,CEACAM1,HSPD1,CD40,HLA-B,PRKCZ,ADA,IRF1,CR1,CCR2,IL4,TNF,EXOSC3,PKN1,P2RX7,MALT1,IL2,ZP3,CD80,HMGB1,BTK,CLC,LILRB1,BCL6,FOXJ1,TNFSF4,PRKCQ,MEF2C,PAXIP1,JAK3,DUSP10,CD4,HLA-E,SUSD4,IL12RB1,FOXP3,PPP3CB
GO:0045939	negative regulation of steroid metabolic process	GO_NEGATIVE_REGULATION_OF_STEROID_METABOLIC_PROCESS	0.236178800694074	0.743345674392492	0.833471753132901	0.948864204293128	21	REST,CYP27B1,DKK3,INSIG1,SOD1,NFKB1,PROX1
GO:0000018	regulation of dna recombination	GO_REGULATION_OF_DNA_RECOMBINATION	0.202618947223237	0.790500063204135	0.833586966251902	0.948864204293128	52	UNG,FIGNL2,FBXO18,ZRANB3,CD40,TERF2IP,IL4,EXOSC3,RAD51AP1,PRDM9,IL2,BCL6,MRE11A,TNFSF4,UBE2B,PAXIP1,FIGN,MLH1,PPP4R2,FOXP3
GO:2000736	regulation of stem cell differentiation	GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION	0.18622554632599	0.826587027952572	0.833706587651599	0.948864204293128	104	ELL3,CLASP1,PRICKLE1,HDAC2,KDM2B,BCL9L,YAP1,GSK3B,REST,TGFBR2,EPHA3,SOX5,GLIPR2,EZH2,GCNT2,TBX5,NKX2-5,SP7,SOX9,SMAD7,SMAD3,BAMBI,HPN,TGFB3,CNOT1,TWIST1,TACSTD2,OLFM1,CLASP2,SMO,ZNF706,ZFP36L2,EIF2AK2,SIX4,STRAP,PDGFRA,OVOL2,N4BP2L2,DAG1,FUZ,TAL1,HOXB4,LTBP3,TGFB1,SNAI1
GO:0060009	sertoli cell development	GO_SERTOLI_CELL_DEVELOPMENT	-0.248590304236267	-0.732338889956454	0.834144968941411	0.948864204293128	15	DMRT1,SDC1,RAB13
GO:0031954	positive regulation of protein autophosphorylation	GO_POSITIVE_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION	0.23580784207783	0.742178124714225	0.834948230994962	0.948864204293128	21	PDGFB,CALM3,CALM1,RAP2C,VEGFA,MRE11A,ACE,RAP2A,NEK10
GO:0002931	response to ischemia	GO_RESPONSE_TO_ISCHEMIA	0.224944600147482	0.755029305292002	0.835009065435965	0.948864204293128	27	CAMK2A,PPIF,PANX1,SLC26A5
GO:0006309	apoptotic dna fragmentation	GO_APOPTOTIC_DNA_FRAGMENTATION	0.253384396143834	0.728091821203719	0.835164222383316	0.948864204293128	15	DICER1,DNASE2B,CECR2,HMGB1,ENDOG,H1F0,KPNB1
GO:0050931	pigment cell differentiation	GO_PIGMENT_CELL_DIFFERENTIATION	0.226304737778887	0.752511664951432	0.835273840737821	0.948864204293128	26	MREG,C10orf11,USP13,MITF,TYRP1,MEF2C,AP1G1
GO:0051783	regulation of nuclear division	GO_REGULATION_OF_NUCLEAR_DIVISION	0.179425890557956	0.842644244122788	0.835679252889008	0.948864204293128	150	LRP5,PCID2,AURKAIP1,CDC26,PDGFB,CSNK2A1,PIN1,MAD2L1,GOLGA2,FZR1,OSM,OBSL1,PTEN,PRKAR1A,GORASP1,CEP85,TGFA,NME6,DAPK3,ANAPC11,APC,CDC25C,DLGAP5,PRDM9,CUL9,ATRX,KLHL22,TPR,MAD1L1,FGF8,TOM1L2,UBE2B,EGF,ESPL1,MSX1,MAD2L1BP,CCDC8
GO:0090183	regulation of kidney development	GO_REGULATION_OF_KIDNEY_DEVELOPMENT	-0.1967810285286	-0.801031550291288	0.835938565002045	0.948864204293128	54	PAX8,OSR1,WT1,BMP4,WNT2B,GATA3,CTNNB1,ADIPOQ,GDNF,WNT9B,BASP1,MYC,PDGFD
GO:0006739	nadp metabolic process	GO_NADP_METABOLIC_PROCESS	-0.220089666041403	-0.761970786539013	0.83614176523712	0.948864204293128	27	NADK,PGLS,TP53I3,KCNAB2,H6PD,CYB5R4,PGM2,TPI1,RPE,NOX1,NUDT12,FMO2
GO:0050730	regulation of peptidyl tyrosine phosphorylation	GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION	0.175485532021047	0.856035723629953	0.836397847687585	0.948864204293128	199	EHD4,AGT,NRP1,FBXW7,PDGFB,HDAC2,DVL2,APP,UNC119,ITGB3,ARHGEF2,ADRA2C,ZGPAT,CTF1,VEGFB,OSM,JAK2,CSF3,GH1,CD300A,CD40,TGFA,GPRC5B,PRKCZ,RAP2C,ERBB4,EPHA7,MTOR,IL4,CSF2,SOCS4,ITGB2,CNTN1,VEGFA,SH3BP5L,TMEM102,IL11,IL2,CD80,HYAL2,CD36,MLST8,LRRK1,PRKCE,TNFRSF18,TNFRSF14,TREM2,EGF,INPP5F,TEC,CSPG4,IL21,IBTK,HSPH1,IL22RA2,EREG,ACE
GO:0048520	positive regulation of behavior	GO_POSITIVE_REGULATION_OF_BEHAVIOR	-0.226655502853574	-0.751776328940517	0.836874451273046	0.948864204293128	23	NLGN1,NPY2R,NR4A3
GO:0009267	cellular response to starvation	GO_CELLULAR_RESPONSE_TO_STARVATION	-0.180314064398308	-0.837256345684391	0.837297583008986	0.948864204293128	109	DAP,WNT2B,SLC38A2,GAS2L1,ATF3,XBP1,AKR1C3,TBL2,SH3GLB1,CDKN1A,EIF2AK3,PPM1D,USP33,PCK1,EIF2AK4,PICK1,FOXA3,MYOD1,KIAA1324,RRAGC,CPEB4,CARTPT,WNT9B,BHLHA15,SLC2A1,NFE2L2,IFI16,SIRT1,SLC39A4
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	GO_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.243294227038142	0.734016646684256	0.837495590173979	0.948864204293128	18	HDAC9,STARD13,DLL4,CCR2,VEGFA,HDAC5,FOXC2
GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS	0.174100478367309	0.859460223798151	0.837626126347119	0.948864204293128	218	CUL4A,NOL9,DCP2,ELAC2,KIAA0391,NCBP1,SMG6,WDR33,EXD2,EXOSC4,ABT1,EXOSC7,TUT1,RCL1,CLP1,TREX2,FBXO18,RNASEH2C,ZRANB3,PAN2,CNOT6L,ERCC1,GTF2H3,REV3L,SPO11,EXOG,POLG,CPSF1,POLD2,ERCC4,EDC3,NCBP2,RFC3,EXOSC3,MOV10,DICER1,PLD6,GTF2H5,DNASE2B,DCP1A,CNOT8,CECR2,HMGB1,ENDOG,TSN,ENPP3,G3BP1,POLK,MRE11A,H1F0,ISG20L2,FAN1,CNOT1,SLFN14,RNASE7,RPP14
GO:0006266	dna ligation	GO_DNA_LIGATION	-0.247554124427675	-0.729286338196035	0.837889314546674	0.948864204293128	15	XRCC1,TOP2A,HMGB2,XRCC4
GO:0045880	positive regulation of smoothened signaling pathway	GO_POSITIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY	-0.226220868201805	-0.750334722454799	0.838454784899034	0.948864204293128	23	WNT9A,FOXA1,KIF7,FGF9
GO:0001773	myeloid dendritic cell activation	GO_MYELOID_DENDRITIC_CELL_ACTIVATION	0.227842460628626	0.750126350964853	0.838560496228735	0.948864204293128	25	BATF2,TGFBR2,IL4,CSF2,SPI1,HMGB1,LTBR,UBD,DHRS2,TRAF6,TGFB1
GO:0034695	response to prostaglandin e	GO_RESPONSE_TO_PROSTAGLANDIN_E	-0.224120373584055	-0.752418148875525	0.838713922273884	0.948864204293128	24	CCL19,P2RY4,CCL21,PPARG,PTGER2
GO:1902931	negative regulation of alcohol biosynthetic process	GO_NEGATIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS	0.246290075549655	0.731656800619148	0.838826067549472	0.948864204293128	17	REST,CYP27B1,DKK3,SOD1,NFKB1
GO:0071383	cellular response to steroid hormone stimulus	GO_CELLULAR_RESPONSE_TO_STEROID_HORMONE_STIMULUS	0.175064233173635	0.855809926696291	0.839193662609727	0.948864204293128	202	NR1I2,NR3C2,PPARD,ESRRA,NR2F6,PPARA,ROCK2,ESR1,ATP1A2,RNF14,UGT3A2,ABHD2,NKX3-1,JAK2,REST,MED24,MED12,RXRB,AGTR2,UBR5,H2AFZ,AR,RXRG,EP300,MED17,RAMP3,RHOXF1,ESR2,THRAP3,FOXO1,HMGCS2,FHL2,RXRA,TRIM24,NCOA3,ESRRG,PELP1,TRIP4,NPC1,ELK1,CRHBP,IL17A,NCOA1,ABCG2,NR2F1,ATP1A3,WBP2,DDX54
GO:0090659	walking behavior	GO_WALKING_BEHAVIOR	0.219856211437683	0.757729720344031	0.839337504332123	0.948864204293128	30	SCN1A,DRD2,HIPK2,CHD7,CLN8,NPC1,EPHA4,FXN,GLRA1,CNTN2,KLHL1
GO:0060135	maternal process involved in female pregnancy	GO_MATERNAL_PROCESS_INVOLVED_IN_FEMALE_PREGNANCY	0.198365507006255	0.791212555448745	0.839850493904067	0.948864204293128	58	PPARD,PPAT,ESR1,GHSR,CYP27B1,ADCY7,STC2,MMP7,MTOR,RXRA,DEDD,APOL2,NPFF,KPNA6,PRDX3,MED1,NR2F2
GO:0048525	negative regulation of viral process	GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS	-0.185760689997016	-0.821149459279692	0.840483919938342	0.948864204293128	82	IFITM2,SLPI,CCL3,TRIM11,BTBD17,MID2,TRIM62,APOBEC3F,FCN3,TRIM35,EIF2AK4,MBL2,INPP5K
GO:0001754	eye photoreceptor cell differentiation	GO_EYE_PHOTORECEPTOR_CELL_DIFFERENTIATION	-0.203969169262289	-0.781283987075823	0.840486537341517	0.948864204293128	41	PRKCI,PDE6C,ROM1,GNAT1,STAT3,TULP1,RDH13,NRL
GO:0010633	negative regulation of epithelial cell migration	GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.203047294012952	0.782049518293947	0.840611235955056	0.948864204293128	49	PTPRM,CSNK2B,BMP10,SP100,STARD13,AGTR2,DLL4,PTPRG,IL4,HMGB1,PFN2,HDAC5,NR2F2,TACSTD2
GO:1900026	positive regulation of substrate adhesion dependent cell spreading	GO_POSITIVE_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING	0.227328647660662	0.748434723137127	0.840615881521719	0.948864204293128	25	UNC13D,C1QBP
GO:0051348	negative regulation of transferase activity	GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY	0.169495389010985	0.876049133821394	0.841167809249379	0.949168905777207	326	LRP5,ADAR,CDK5RAP1,CDC26,NPM1,TRIB2,RGS3,LRP6,PSMD11,CRIPAK,PSMD2,PSMC6,TAOK3,WNK1,MCRS1,EPHA1,TSC2,MAD2L1,ZGPAT,ADARB1,FZR1,HMGCR,PKIA,GSK3B,CAV3,PTEN,OBFC1,CHORDC1,CDK5RAP3,ANAPC1,PRKAR1A,MLLT1,CD300A,PSMC5,PSMB7,LIMK1,LRTM1,DNAJA3,CEP85,LATS1,LAX1,FBXO31,COX11,DUSP19,ANAPC11,DUSP21,CDKN1B,RGS14,PARK7,SOCS4,PIK3IP1,CDK1,PSMD8,SH3BP5L,PKN1,PSMB10,APC,HSPB1,TRIB3,GADD45A,DUSP3,LRRTM3,AKT1S1,PSMD3,PSMB1,HYAL2,SMAD7,DUSP7,HEXIM2,PSMA5,PSMB9,CHAD,DUSP4,PRDX3,YWHAG,PAQR3,DUSP26,PPP1R1C,NR2F2,PSMD6,IBTK,CHCHD10,PKIB,PPP1R1B,PSMB3,PSMB6,PSMD1,DUSP10,SPRY2,SMPD1
GO:0048593	camera type eye morphogenesis	GO_CAMERA_TYPE_EYE_MORPHOGENESIS	0.186725646315623	0.817921953385084	0.841463625516609	0.949184505190653	96	LRP5,PTPRM,ZEB1,TBX2,MFN2,LRP6,KDM2B,PROM1,HIPK2,RPE65,RP1,CRYGB,GDF11,GNAT2,TSPAN12,VEGFA,PAX6,SOX9,CABP4
GO:0002544	chronic inflammatory response	GO_CHRONIC_INFLAMMATORY_RESPONSE	0.251263997388241	0.721998924343717	0.841930147400509	0.949392588324997	15	UNC13D,GJA1,TNF,VNN1
GO:0048232	male gamete generation	GO_MALE_GAMETE_GENERATION	-0.163014598886409	-0.9008590006115	0.842268974097953	0.949456586340827	405	SPANXA1,GAL3ST1,CFTR,TDRD1,DIAPH3,TYRO3,CNR1,SSTR3,TARBP2,PRSS21,RARA,CYP26B1,SPANXB1,AGFG1,SSTR2,PYGO1,WFDC2,DMRT1,FSHR,GALNTL5,PGM3,TDRD12,IQCF1,SPAG6,SKIL,TXNDC2,CALR,XRN2,FANCF,CETN2,ACSBG2,GGNBP1,SYCE3,TNP2,INSL3,SGPL1,REC8,PTCHD3,FAM9A,TBP,BCAP31,YBX2,RFX2,SPATA19,SERPINA5,MOV10L1,CCNB1,YY1,TSSK6,ADCY10,SPEF2,TAF4B,SHCBP1L,GGT1,SBF1,FAS,CYLC2,MEA1,DDX25,TTC26,PRKACG,MYCBPAP,SPATA16,FOXA3,KHDRBS3,BAX,HMGB2,RNF8,TSNAXIP1,AURKC,NPHP1,CRTAP,OAZ3,TMF1,PYGO2,ZFP41
GO:0071158	positive regulation of cell cycle arrest	GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST	-0.186258918853251	-0.815674522389292	0.843441992683552	0.950088445120644	78	SFN,FAP,MUC1,CNOT6,TP73,CDKN1A,UBA52,CCNB1,RNF112,CHEK2,BAX,E2F4,TRIAP1,INSM1,PKD2,BTG2,MDM2,UBB,CNOT7,PCNA
GO:0046324	regulation of glucose import	GO_REGULATION_OF_GLUCOSE_IMPORT	-0.19378295742748	-0.797555389974541	0.843484000182075	0.950088445120644	57	ITLN1,FFAR3,PRKCI,MZB1,OSTN,ADIPOQ,LEP,HK2,RHOQ,RARRES2,SIRT6
GO:0098754	detoxification	GO_DETOXIFICATION	0.194359722960742	0.796243335882264	0.843835326862438	0.950088445120644	66	KDM3B,GSR,ATP7A,TXNRD1,GPX6,MGST3,GPX5,PRDX2,SOD2,HBA1,PARK7,IPCEF1,SOD1,TPO,CCS,SLC30A1,PRDX3,PRDX5,SRXN1,MT3,CYGB,MGST2,SOD3,HBB,PXDNL,PRDX6,GSTM1,GSTO1
GO:0034599	cellular response to oxidative stress	GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS	0.176709962205808	0.845333203531228	0.844083696483816	0.950088445120644	171	ATP7A,EPAS1,TXN2,ANKRD2,HDAC2,LRRK2,IL18BP,CHD6,CPEB2,GUCY1B3,MTR,PPIF,PINK1,GSK3B,JAK2,PTPRK,SLC8A1,EZH2,PPP5C,PXN,EP300,SETX,GPX5,LONP1,TXNL1,FOXO1,PRDX2,SOD2,PARK7,HDAC6,CDK1,ETS1,SOD1,ZNF622,TPO,CCS,IMPACT,FXN,CD36,ENDOG,ATP2A2,PCGF2,ROMO1,PRDX3,TRPC6,PRDX5,NFE2L1,AIFM1,MT3,SOD3,BNIP3,SIRT2,SIN3A,ARG1,PPARGC1A,DNM2,ETV5,DHRS2,CBX8,MAPT,TXNDC8,CCL5,PNPT1,PDGFRA,TMEM161A
GO:0009799	specification of symmetry	GO_SPECIFICATION_OF_SYMMETRY	0.184489470665313	0.821383183790677	0.844644331315355	0.950088445120644	106	DNAI2,TBX2,PCSK6,RTTN,NDRG4,C2CD3,MEGF8,HAND2,PKD1L1,IFT172,GJA1,SUFU,SHH,DAND5,WNT8B,TBX20,NKX2-5,SOX17,DNAI1,ENG,SETDB2,MKKS,SMAD3,FGF8,FOXJ1,TBX3,NOTO,MEF2C,SRF
GO:0051220	cytoplasmic sequestering of protein	GO_CYTOPLASMIC_SEQUESTERING_OF_PROTEIN	-0.204243694606158	-0.777755160795138	0.844725643896976	0.950088445120644	40	KDELR3,TSPO,KDELR2,HK2,KEAP1,PSMD10,PKD2,GET4,YWHAB,IL10,TONSL,SRI
GO:1902745	positive regulation of lamellipodium organization	GO_POSITIVE_REGULATION_OF_LAMELLIPODIUM_ORGANIZATION	-0.226429536025083	-0.742338178933369	0.844805322711256	0.950088445120644	22	CORO1C,HSP90AA1,RAC1,ENPP2,FSCN1,CORO1B,NCKAP1
GO:0010523	negative regulation of calcium ion transport into cytosol	GO_NEGATIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL	0.244382353001774	0.725989506990949	0.845242523434013	0.950262636566095	17	CALM3,CALM1,TRDN,CASQ2,GSTO1,TGFB1,CLIC2,EPO,CALM2
GO:1904589	regulation of protein import	GO_REGULATION_OF_PROTEIN_IMPORT	0.176407256503677	0.844501579015832	0.845680244941427	0.950437296985924	172	PIK3R1,RBCK1,PYDC2,HNRNPM,AKAP1,C8orf4,SUFU,PKIA,GSK3B,AKAP6,JAK2,DDX58,CSF3,CABP1,RGS20,MBTPS1,AGTR2,UBR5,PDE2A,SHH,EP300,ERBB4,PPP3R1,MTOR,IL18R1,TNF,SEMA5A,TMEM173,EMD,CDK1,FAF1,KANK1,MDFI,HYAL2,CD36,SMAD3,TPR,BAMBI,LITAF,NFKBIA,EGF,TLR4,TGFB3,FAM89B,MED1,EDA,PRKCQ,JUP
GO:0050655	dermatan sulfate proteoglycan metabolic process	GO_DERMATAN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS	-0.240591805766313	-0.722917834270623	0.846483537892071	0.950836213547418	16	IDUA,DCN,DSEL,VCAN,DSE,NCAN,CHST12,CSGALNACT2,BGN,CHST14,CSPG5,UST,BCAN,CSGALNACT1,B3GAT3,CSPG4
GO:0033522	histone h2a ubiquitination	GO_HISTONE_H2A_UBIQUITINATION	0.247065672442077	0.721909841618317	0.846705696496608	0.950836213547418	16	KDM2B,BCOR,RNF168,UBE2B,UBR2
GO:0043124	negative regulation of i kappab kinase nf kappab signaling	GO_NEGATIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING	0.203223288471496	0.775751551306792	0.846882640586797	0.950836213547418	47	CARD8,PYDC2,ESR1,DNAJA3,FAF1,RHOH,OTUD7A,TRIM59,LITAF,NFKBIA,PER1,PPM1B,NFKBID,STAT1,TNIP3
GO:1903859	regulation of dendrite extension	GO_REGULATION_OF_DENDRITE_EXTENSION	-0.237540056122407	-0.726469757826241	0.847385041311589	0.951083044032947	17	SYT4,SYT17
GO:0098542	defense response to other organism	GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM	-0.161914369925169	-0.903293980468733	0.84788465948177	0.951145021376952	446	PLA2G2A,IFITM2,SLPI,DEFA5,POLR3D,SNRPB2,PRB3,ANXA3,DEFB123,CPA3,MUC5B,ALPK1,TRIM11,HP,AGBL5,DEFB124,SLFN11,LENG9,FGF7,CEBPB,ANXA5,MB21D1,DEFA6,TMEM39A,DEFB133,HIST1H2BE,HIST1H2BK,S100A12,POLR3G,DEFB132,PYCARD,RIPK2,APOBEC3F,HCAR1,IFNA14,LGALS8,KLK3,FGFBP1,SEMG2,FCN3,UBA52,IRF7,IRF4,MSTN,TNFRSF1A,IGHG4,PHYHIP,IL17RC,ZCCHC17,IGHG2,EXOSC5,IGHG1,HPR,C5AR1,S100A9,IFNE,SLC25A19,LMCD1,EIF2AK4,DEFB121,MBL2,PGLYRP1,CLEC4E,IGHD,IFNA16,YIPF1,NLRP3,TLR9,HIST1H3C,FABP1,IFNAR1,NOD1,IGKC,HMGB2,SNRPB,DNAJC3,DEFB114,DROSHA,TLR2,IGLL1,TMF1,UNC93B1,IGLC1,CEBPE,GPAM,HIST1H2BF,TEAD4,ELANE,CHST3
GO:1903429	regulation of cell maturation	GO_REGULATION_OF_CELL_MATURATION	0.240326530863437	0.725063132163779	0.848023469558275	0.951145021376952	18	LRRK2,GSK3B,NPR2,MTOR,OPA1,SIRT2,PPP2R1A
GO:0042069	regulation of catecholamine metabolic process	GO_REGULATION_OF_CATECHOLAMINE_METABOLIC_PROCESS	-0.244355994083492	-0.719864751005052	0.848429755643573	0.951145021376952	15	SNCA,SLC6A3,CHRNB2,ABAT,PDE1B,NR4A2
GO:0009299	mrna transcription	GO_MRNA_TRANSCRIPTION	-0.230084254362366	-0.735248638358094	0.848570558287281	0.951145021376952	20	LMO2,HIF1A,C5AR1,ZBTB1
GO:0009798	axis specification	GO_AXIS_SPECIFICATION	0.18725665393826	0.80924566758973	0.849522417662717	0.951617326278352	89	LRP5,CXXC4,LRP6,PCSK6,TDRD5,C2CD3,CDX4,PKD1L1,IFT172,RGS20,SHH,PTCH1,PAX6,PLD6,LDB1,SETDB2,CDX2,HEY2,BCOR,MDFI,LHX1,EGF,TBX3,GDF3
GO:0032891	negative regulation of organic acid transport	GO_NEGATIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT	0.243154285924799	0.722341273798929	0.849557357536081	0.951617326278352	17	AKT2,AGTR2,GABBR1,NPY5R
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE	-0.223473753928939	-0.741223028905627	0.850460930640913	0.951924163753165	23	BBC3,PTPN2,XBP1
GO:0070304	positive regulation of stress activated protein kinase signaling cascade	GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE	-0.176266267229621	-0.841060563903288	0.850676302553836	0.951924163753165	129	EDA2R,TNFSF11,CCL19,ARHGEF5,TRAF4,WNT5A,BMP2,CTGF,MDFIC,EDAR,PYCARD,CCL21,RIPK2,RIPK1,LEP,STK3,RPS3,ARL6IP5,TLR9,MAP3K11,NOD1,MID1,EDN1,CDC42,FCER1A,MAP3K2,RASSF2,AXIN1,CARD9,PDCD10,WNT7A,HRAS,DUSP22,TLR3,PTK2B,MAP3K5,DUSP15,CRHR2,MAP3K7,MAP3K9
GO:0006023	aminoglycan biosynthetic process	GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS	-0.18000998255407	-0.826365236023304	0.85067970426902	0.951924163753165	102	AGRN,B3GALT6,GPC5,FMOD,ANGPT1,SDC1,UGDH,EXTL2,HAS1,B4GALT7,B4GALT2,NDST3,GALNT5,B4GALT5,EXT1,HS3ST5,DCN,EXTL1,CHST3,B4GALT4,B3GAT1,DSEL,CYTL1,CHST6,VCAN,B4GALT1,B3GNT2,LUM,CHPF,B3GNT4
GO:2000647	negative regulation of stem cell proliferation	GO_NEGATIVE_REGULATION_OF_STEM_CELL_PROLIFERATION	-0.239174408294334	-0.718658911538489	0.85163538757928	0.952676874241228	16	BMP4,WNT5A
GO:0002719	negative regulation of cytokine production involved in immune response	GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	-0.228892003039337	-0.731438724619029	0.852508594055959	0.952908584153429	20	APOA2,ANGPT1,IRAK3,CUEDC2,IL10,IFNA2,HMOX1
GO:0071467	cellular response to ph	GO_CELLULAR_RESPONSE_TO_PH	0.242179226435715	0.719444653199806	0.852551703615533	0.952908584153429	17	INSRR,PKD2L1,HYAL1,IMPACT,SLC38A3,GPLD1,GNA11,KCNK18,HVCN1
GO:0050856	regulation of t cell receptor signaling pathway	GO_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY	0.220967684729698	0.741680739986917	0.852773657125066	0.952908584153429	27	LGALS3,CEACAM1,CD300A,ADA,GBP1,DUSP3,MALT1
GO:0006044	n acetylglucosamine metabolic process	GO_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS	-0.242905242596939	-0.715590884666906	0.852974915048806	0.952908584153429	15	AMDHD2,EXTL2
GO:0032069	regulation of nuclease activity	GO_REGULATION_OF_NUCLEASE_ACTIVITY	0.230982706597387	0.726991564459009	0.853607219976745	0.953127452523161	21	NPM1,OAS3,OAS1,HMGB1,VAPB,BAK1
GO:0007033	vacuole organization	GO_VACUOLE_ORGANIZATION	0.177393235300858	0.833947410169767	0.853737156671815	0.953127452523161	151	ATG14,TP53INP2,MFN2,ALS2,VPS4A,LRRK2,ARFGEF2,ATG16L1,ARF1,SYT7,VPS11,CHMP7,PIK3C3,CLN8,VPS37B,WIPI2,TMEM127,MBTPS1,VPS39,ATG9A,P2RX7,TFEB,MAP1LC3A,GNPTAB,VPS37C,TMEM175,WDR45,FASLG,CHMP6,ATG16L2,UVRAG,ATP6V0C,MAP1LC3B,TSG101,VPS37A,MT3,CLCN3,CHMP1B,CLN6,CHMP4B,PACS2,ATG3,CHMP4C,ATG4D,TMEM165,RAB14,STX6,SNX14,EPG5,VPS33B,RAB20,MAN2A1,VPS4B,AKTIP,NAGLU,STAM
GO:0051983	regulation of chromosome segregation	GO_REGULATION_OF_CHROMOSOME_SEGREGATION	0.190551068746519	0.797200842066385	0.8542857645424	0.953423701409058	74	SPAG5,PCID2,CDC26,CSNK2A1,MAD2L1,GOLGA2,PTEN,GORASP1,ANAPC11,APC,DLGAP5,SFPQ,ATRX,KLHL22,TPR,MAD1L1,ESPL1
GO:0050858	negative regulation of antigen receptor mediated signaling pathway	GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY	0.235154096636285	0.719599121209354	0.856385738640575	0.955336599790391	19	LGALS3,CEACAM1,CD300A,GBP1,DUSP3
GO:0060338	regulation of type i interferon mediated signaling pathway	GO_REGULATION_OF_TYPE_I_INTERFERON_MEDIATED_SIGNALING_PATHWAY	-0.205208808361592	-0.762754246983523	0.856942308977873	0.955336599790391	36	WNT5A,PTPN2,IFNA14,IRF7,IFNA16,IFNAR1
GO:0034110	regulation of homotypic cell cell adhesion	GO_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	-0.165117545355491	-0.880246764117371	0.85720387623802	0.955336599790391	289	PRKCA,CD55,DPP4,TNFSF11,CCL19,EFNB3,RARA,IL18,CYP26B1,BMP4,TNFRSF21,PTPN2,TNFSF14,GATA3,CEBPB,HLA-DRB5,C1QTNF1,IL27,ANXA1,MAP3K8,XBP1,PLA2G2D,CTNNB1,IL6ST,PYCARD,CCL21,NR4A3,RIPK2,IL36B,IRF4,RIPK3,ADAMTS18,CASP3,LEP,TNFSF9,LILRB2,RAG1,ZBTB1,PAK3,LAT,PRELID1,NLRP3,SART1,BTLA,GRAP2,PDPK1,NKAP,ZNF703,ABAT,IL2RA,LMO1,VTCN1,CDC42,HLA-DRB1,GPAM
GO:0016050	vesicle organization	GO_VESICLE_ORGANIZATION	0.170729194891023	0.858067181228667	0.857510396271905	0.955336599790391	254	C2CD4A,DYSF,LRSAM1,SYT9,DLG4,KIF13A,SNX11,SEC24C,PAFAH1B1,ALS2,SYT8,VPS4A,FABP9,TRAPPC9,SYTL2,VAMP2,GOLGA2,F8,STX1A,ARF1,SYT7,VPS11,RAB1B,CHMP7,GRIA1,VPS37B,PTPRN,CADPS,GORASP1,TGFA,VTI1A,VPS39,STX4,WASL,SNX30,FNBP1L,MITD1,SEC22C,CREB1,SYT12,PPP6R1,SYTL3,P2RX7,VAMP1,RPH3AL,GOSR1,TRAPPC5,VPS37C,SORT1,TMEM175,GBF1,C2CD4B,CHMP6,VAPB,TRAPPC2,CD59,UVRAG,RAB3A,SNX19,TSG101,TYRP1,STX10,DOC2B,SEC23IP,VPS37A,SYP,LRMP,SYTL4,SEC16A,AP1G1,SEC24B,GOLPH3,CHMP1B,STX8,ZFYVE16,FCHO1,CHMP4B,ATP8A1,ZPBP2,PIK3C2A,CHMP4C,NAPA,EPS15,SERPINA1,BET1,RAB14,TRAPPC4,STX7
GO:0009410	response to xenobiotic stimulus	GO_RESPONSE_TO_XENOBIOTIC_STIMULUS	0.187581480800807	0.800761313039235	0.857676986511985	0.955336599790391	83	NR1I2,SULT1A2,CYP2D6,SCGB1A1,CYP2E1,MCM7,CYP2B6,AIP,CYP2F1,MGST3,DNAJA2,GSS,AKR7L,RHBDD3,CYP3A4,UGT2B11,NAT1
GO:0097194	execution phase of apoptosis	GO_EXECUTION_PHASE_OF_APOPTOSIS	-0.194136115591804	-0.783760016506327	0.857702675153465	0.955336599790391	52	BBC3,BNIP1,AIFM3,BCAP31,ACVR1C,TOP2A,CASP3,CASP6,HMGB2,DNASE2,CIDEC
GO:0048535	lymph node development	GO_LYMPH_NODE_DEVELOPMENT	0.240376488774076	0.714089239397904	0.858689183157268	0.956119017700088	17	RC3H2,RC3H1,TGFB1,CD248,LTB,IL15
GO:0071347	cellular response to interleukin 1	GO_CELLULAR_RESPONSE_TO_INTERLEUKIN_1	0.188981558676916	0.79624684417124	0.859491516502027	0.956695914201661	77	CCL1,HSPA9,P2RY2,VLDLR,XCL1,CCL24,NKX3-1,IL1RL2,CX3CL1,IKBKB,ADAMTS7,CCL16,SOX9,MYLK3,HYAL1,IL17A,NFKB1,HYAL2,CCL23,PSMB9
GO:2000380	regulation of mesoderm development	GO_REGULATION_OF_MESODERM_DEVELOPMENT	-0.24053807879664	-0.708617297683368	0.860398675410688	0.957185184150979	15	SFRP2,SMAD2,ETV2,NODAL,MIXL1,WNT3A,CER1
GO:0050982	detection of mechanical stimulus	GO_DETECTION_OF_MECHANICAL_STIMULUS	-0.201213981460232	-0.766218084757042	0.861142217245241	0.957185184150979	40	PDZD7,PKD1L3,PIEZO2,ANO3,ATP2B2,PKDREJ,TMC2,KCNA1,PKD2,PAWR,TRPA1,HTR2A,COL11A1
GO:0006626	protein targeting to mitochondrion	GO_PROTEIN_TARGETING_TO_MITOCHONDRION	0.202675019037853	0.762952301590891	0.86148581719946	0.957185184150979	44	MFN2,MIPEP,PDE2A,AIP,TIMM8B,IMMP1L,PMPCA,TIMM17B,TIMM22,CHCHD4,BID,NDUFA13,TOMM40L,TIMM13,TOMM40,MTX3
GO:0006893	golgi to plasma membrane transport	GO_GOLGI_TO_PLASMA_MEMBRANE_TRANSPORT	0.207110455882881	0.754827640848407	0.861724424529325	0.957185184150979	38	KIF13A,CCDC93,ARFGEF2,VAMP2,MACF1,GOLGA4,STEAP2,ANK3,STXBP6,COMMD1,SPTBN1,GOLPH3,RAB26,BBS2,DNM2,ARFRP1,GOPC
NA	negative regulation of homeostatic process	GO_NEGATIVE_REGULATION_OF_HOMEOSTATIC_PROCESS	0.180600836282714	0.817231162904533	0.862097792336302	0.957185184150979	117	FLCN,ITPR1,STAT5B,TRPV1,SMG6,CALM3,RYR2,MCRS1,TPCN1,XCL1,DRD2,HMGCR,INPP5D,ERCC1,CALM1,ERCC4,ADA,ACD,TERF2IP,P2RX7,LDB1,CD38,ENY2,TRDN,JPH2,PRKCE,ITPKB
GO:0009953	dorsal ventral pattern formation	GO_DORSAL_VENTRAL_PATTERN_FORMATION	0.185555789455675	0.800443944317412	0.862256890637787	0.957185184150979	88	LRP5,PROP1,CXXC4,LRP6,GLI2,IFT172,SUFU,RGS20,LHX2,SHH,DLL4,WNT8B,TBX20,FKBP8,PTCH1,PAX6,MDFI,LHX1,NKX2-2,FGF8,DSCAML1,EGF,NOTO
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	GO_CELLULAR_COMPONENT_DISASSEMBLY_INVOLVED_IN_EXECUTION_PHASE_OF_APOPTOSIS	0.205635790242814	0.757687736276683	0.862335597629715	0.957185184150979	40	ACIN1,CDK5RAP3,APC,DICER1,DNASE2B,CLSPN,CECR2,HMGB1,ENDOG,SATB1,H1F0,PRKCQ
GO:0035456	response to interferon beta	GO_RESPONSE_TO_INTERFERON_BETA	0.233330770610299	0.714019529678754	0.862371210436587	0.957185184150979	19	XAF1,IRF1,TMEM173,NDUFA13,CDC34,UBE2K,STAT1,PNPT1
GO:0071379	cellular response to prostaglandin stimulus	GO_CELLULAR_RESPONSE_TO_PROSTAGLANDIN_STIMULUS	0.224683804103964	0.724436454924361	0.86264281253444	0.957185184150979	23	GNAS,GNG2,PRKAA2,PRKCE,TNFSF4
GO:1901379	regulation of potassium ion transmembrane transport	GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT	0.194471839507446	0.775682039794614	0.862774761947139	0.957185184150979	58	ANK2,NEDD4L,OPRK1,RNF207,KCNJ2,VAMP2,AKAP6,CAV3,KCNH2,KCNRG,ANK3,KCNIP2,SUMO1,ATP1B2,CASQ2,ACTN2,PRNP,DNM2,KCNAB1,KCNQ1,CAB39,KCNIP4,FHL1,KCNC1
GO:0043122	regulation of i kappab kinase nf kappab signaling	GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING	-0.167782039673248	-0.863211227722702	0.863380679629106	0.957541801526053	216	EDA2R,TNFSF11,CCL19,IL18,IRAK4,PRKD1,TRAF3IP2,TNFSF14,ANGPT1,LPAR1,TRAF5,MID2,IRAK1,EDAR,CTNNB1,TRIM62,S100A12,NLRP6,PYCARD,CCL21,RIPK2,RIPK1,CHUK,TRADD,UBA52,TNFRSF1A,ADIPOQ,TRIM38,IKBKG,NOV,PSMD10,NLRP3,NLRP12,TLR9,NOD1,PDPK1,F2R,BRD4,RHOA,TLR2
GO:0050690	regulation of defense response to virus by virus	GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_VIRUS	0.21514255971759	0.735300861197153	0.865460784492672	0.959151390261469	29	ARF1,AP1M2,CD8B,AP2M1,ELMO1,CD247,AP1G1,CD4,PACS1,EIF2AK2
GO:0007369	gastrulation	GO_GASTRULATION	-0.172463498458317	-0.839436229760233	0.865505551734303	0.959151390261469	146	VTN,TBX6,ITGA3,BMP4,WNT5A,LAMA3,T,FGFR2,UGDH,FOXF1,CRB2,LEO1,ACVR1,OTX2,KLF4,CTNNB1,NR4A3,SMAD2,COL7A1,EXT1,ETV2,EPHA2,ACVR2B,NODAL,DUSP2,LAMB3,COL12A1,INHBA,AXIN1,RPS6,ZBTB17,SYF2,MMP14,ITGB4,WNT3,COL11A1,NOG,GATA6,TWSG1,DUSP1,HSBP1,TRIM15,FOXC1,MMP9,EOMES,MIXL1,FN1,WNT3A,COL6A1,EXT2,BMP7
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND	-0.197758191601934	-0.765581658978151	0.866043123412101	0.959151390261469	43	RIPK1,GDNF,FAS,BAX,WWOX,PPP1CA,IFI6,INHBA,RET,PF4,BCL2,NRG1,MAP2K5,SNAI2,FGF10,IL1A,IL7
GO:0035640	exploration behavior	GO_EXPLORATION_BEHAVIOR	-0.223518531070819	-0.723633428983087	0.866190881512036	0.959151390261469	21	DPP4,ITGA3
GO:0000729	dna double strand break processing	GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING	-0.234858720544105	-0.705691355840377	0.866419897395935	0.959151390261469	16	RBBP8,SMARCAD1,BARD1,NBN,UBE2V2
GO:0050852	t cell receptor signaling pathway	GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY	0.177088204742735	0.821876701645703	0.866806289796815	0.959151390261469	138	PIK3R1,RBCK1,PSMD11,PSMD2,UBE2N,PSMC6,RNF31,BTRC,PTEN,INPP5D,PSMC5,PSMB7,PSME4,CD3G,IKBKB,PSMA8,MAPK1,PSMD8,PSMB10,MALT1,PLCG1,PSMD3,PSMB1,NFKB1,PAG1,PSMA5,PSMB9,CD247,NFKBIA,PRKCQ,PSMD6,PSMB3,PIK3R2,PIK3CB,HLA-DQA1,PSMB6,PSMD1
GO:0060041	retina development in camera type eye	GO_RETINA_DEVELOPMENT_IN_CAMERA_TYPE_EYE	-0.175173831131959	-0.831553343123671	0.866874421775332	0.959151390261469	125	RBP4,IRX5,CDON,BMP4,GPM6A,PAX4,PDE6C,IMPDH2,ROM1,PRPH2,GNAT1,BMPR1B,SLC17A7,HIF1A,TULP1,RDH13,ZNF513,BAX,ACVR2B,RS1,ARHGEF15,NPHP1,RP1L1,NEUROD4,POU4F2,PSEN1,RET,LAMC3,PTF1A,ATOH7,ATP2B1,HPCA,SERPINF1,GRM6
GO:1901661	quinone metabolic process	GO_QUINONE_METABOLIC_PROCESS	-0.212984595366582	-0.737372374501392	0.867111610387894	0.959151390261469	27	CBR3,AKR1C3,CYP4F11,CYP4F2,VKORC1,VKORC1L1
GO:0014812	muscle cell migration	GO_MUSCLE_CELL_MIGRATION	-0.229535466111065	-0.71281180062567	0.868328096218442	0.960114872846795	18	ITGB1BP1,ANXA1,PARVA,NOV
GO:0045446	endothelial cell differentiation	GO_ENDOTHELIAL_CELL_DIFFERENTIATION	0.189891889240457	0.782213768399331	0.868553115810604	0.960114872846795	68	RAPGEF1,NRP1,PPP1R16B,RAPGEF6,BMPER,RAPGEF2,RAB1B,PDE2A,RAP2C,COL18A1,S1PR1,SOX17,ENG,HEY2,RDX,LAMA5
GO:0051784	negative regulation of nuclear division	GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION	-0.197148127079232	-0.763219915044357	0.868965982417879	0.960255908344905	43	TOM1L1,BMP4,DMRT1,PTTG3P,FBXO5,TEX14,PSMG2,ZW10,MOS,NANOS2,FBXO43,RPS6KA2,TERF1
GO:0022616	dna strand elongation	GO_DNA_STRAND_ELONGATION	0.214207631989256	0.732105523349062	0.869421578111596	0.960444053798369	29	POLA2,LIG3,POLD2,GINS3,RFC3,GINS1,MRE11A,PRIM1
GO:0042551	neuron maturation	GO_NEURON_MATURATION	-0.208262772891759	-0.740074500647783	0.870824940791076	0.961678723983845	30	IRX5,AGRN,SPTBN4,PICK1,NRCAM,NTN4,RET,FEV
GO:0010332	response to gamma radiation	GO_RESPONSE_TO_GAMMA_RADIATION	-0.193583032547755	-0.768470051739065	0.871350693818706	0.961779863562399	48	KDM1A,GATA3,MEN1,TP73,DCUN1D3,CHEK2,XRCC2,BAX,MYC,SOCS3,XRCC5,BCL2
GO:2000811	negative regulation of anoikis	GO_NEGATIVE_REGULATION_OF_ANOIKIS	0.239576189409287	0.700026058830678	0.87151751695939	0.961779863562399	16	ZNF304,PTK2,PIK3CA,ITGA5,PTRH2,NOTCH1,NTRK2
GO:0006892	post golgi vesicle mediated transport	GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT	0.187201647180529	0.788747440939389	0.871773726598003	0.961779863562399	77	KIF13A,CCDC93,ARFGEF2,VAMP2,MACF1,VPS13A,ARF1,GOLGA4,KIF16B,VTI1A,TGOLN2,STX4,STEAP2,ANK3,SORT1,GBF1,STXBP6,SCAMP2,COMMD1,SPTBN1,AP1G1,GOLPH3,RAB26,BBS2,DNM2,EPS15,RAB14
NA	single organism membrane budding	GO_SINGLE_ORGANISM_MEMBRANE_BUDDING	-0.185486148784847	-0.788416874473924	0.87285350613284	0.961865289182815	67	TMED10,AREG,PRKCI,SCFD1,TMED2,ANKRD28,SEC24D,SEC24A,SEC13,COL7A1,F5,SEC31A,TMED9,CNIH2,LMAN1,MCFD2,NSF,ATP8A2
GO:0031102	neuron projection regeneration	GO_NEURON_PROJECTION_REGENERATION	0.2111644096444	0.73362255787204	0.873090524627219	0.961865289182815	31	ULK1,MTR,LAMB2,CTNNA1,JAK2
GO:0002092	positive regulation of receptor internalization	GO_POSITIVE_REGULATION_OF_RECEPTOR_INTERNALIZATION	0.22185693670126	0.715321931481415	0.8735167701407	0.961865289182815	23	DRD2,PCSK9,GH1,HAMP,VEGFA
GO:0071214	cellular response to abiotic stimulus	GO_CELLULAR_RESPONSE_TO_ABIOTIC_STIMULUS	0.169620041932308	0.849208611091863	0.873757713543358	0.961865289182815	246	AGT,DDX3X,BAD,PIK3R1,RHO,FBXW7,HABP4,CREBBP,N4BP1,CAPN3,ATP1A2,YAP1,KCNJ2,ARHGEF2,RPE65,GJA1,HDAC4,BAG3,GSK3B,REST,PTPRK,SLC12A6,CD40,NFATC4,TRPM1,PDE2A,TLK2,INSRR,EP300,MYLK,ERCC4,TNFRSF10B,CASP8AP2,MMP7,IRF1,ESR2,ADSSL1,OPN5,RAD51AP1,SLC2A4,CYBA,USP28,GTF2H5,HUS1,GADD45A,SOX9,PKD2L1,PBK,HYAL1,IMPACT,SLC38A3,ELK1,PTAFR,NFKB1,HYAL2
GO:0051023	regulation of immunoglobulin secretion	GO_REGULATION_OF_IMMUNOGLOBULIN_SECRETION	-0.232598587750603	-0.698900225531352	0.873758036236119	0.961865289182815	16	RBP4,XBP1,IL5
GO:0055076	transition metal ion homeostasis	GO_TRANSITION_METAL_ION_HOMEOSTASIS	-0.177314620613224	-0.811672852766339	0.87378433004399	0.961865289182815	100	STEAP3,STEAP1,EPB42,SLC39A8,NEO1,MT2A,SLC39A6,CP,SLC39A10,FBXL5,HIF1A,SLC31A1,BDH2,S100A9,SLC30A8,FTHL17,LCN2,ATP7B,SLC22A17,MYC,SCARA5,SLC25A37
GO:1903670	regulation of sprouting angiogenesis	GO_REGULATION_OF_SPROUTING_ANGIOGENESIS	0.217160278218285	0.72210438070026	0.874108436164946	0.961865289182815	26	HDAC9,PPP1R16B,STARD13,DLL4,CCR2,VEGFA,HMGB1,HDAC5
GO:0002263	cell activation involved in immune response	GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.176691453037001	0.816430971817247	0.874137231019082	0.961865289182815	134	RC3H2,ATP7A,UNC13D,ITFG2,LFNG,TSC1,MFNG,KLRF2,VAMP2,HSPD1,C8orf4,LBP,ERCC1,PI4K2A,LAT2,ADA,IL18R1,AICDA,IL4,EXOSC3,SH2D1B,ITGAL,HMGB1,GBF1,S100A13,LILRB1,RNF168,PRKCE,IFNA21,TLR4
NA	positive regulation of neurological system process	GO_POSITIVE_REGULATION_OF_NEUROLOGICAL_SYSTEM_PROCESS	-0.225268790244158	-0.709496227967312	0.874494982405839	0.961944480646423	19	MAG,HGF,CARTPT,HCRT,PAWR,NRG1,PARD3,WASF3
GO:0043900	regulation of multi organism process	GO_REGULATION_OF_MULTI_ORGANISM_PROCESS	0.164548658221342	0.874728068908777	0.874934589220304	0.962113631922751	432	DPF3,SMARCB1,P2RY1,ADAR,LRSAM1,DDX3X,BAD,PDE5A,RSAD2,SPINK8,MYOM1,SCN1A,MAP1A,C1QBP,TNIK,ZP2,DRD4,VIP,ACIN1,VPS4A,P2RY2,FCN1,RAD23A,SASH1,TRIM26,SPN,HIST1H3G,PCBP2,HIST1H3B,HERC5,SP100,ADARB1,RNASE10,ARF1,TAP2,DDX58,REST,LBP,CFL1,NPR2,VPS37B,AP1M2,PM20D1,MDH1,TRIM13,IFIT1,MTSS1,EP300,MYLK,PTGDS,ADA,POLR2I,OASL,OAS3,OAS1,CCR2,LSM4,ANKRD17,SIGIRR,IL4,TNF,TMEM173,APOBEC3D,CD8B,TRIM32,AP2M1,ALKBH5,P2RX7,CYBA,CD93,ARHGDIB,HIST1H3E,REP15,PLAU,TRIM31,C1orf210,ZNF189,PTAFR,OVGP1,ITPKC,ZP3,APOBEC3H,ELMO1,CD36,CA7,ZNF502,RHBDD1,VAPB,LILRB1,FUCA2,FAM13B,PTX3,MRE11A,CD247,HPN,GTF2F2,PROX1,POLR2C,APCS,OSBP,TSPAN32,FCGR3B,MBD5,TSG101
GO:0008286	insulin receptor signaling pathway	GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY	-0.183061217556194	-0.789925328702617	0.875425396457923	0.962338956393655	72	ATP6V1C2,ATP6V1B1,PTPN2,BAIAP2L2,ATP6V0D1,ATP6V1H,IGFBP1,BAIAP2,RHOQ,AP3S1,NAMPT
GO:0046889	positive regulation of lipid biosynthetic process	GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS	0.19225592008112	0.76684349070192	0.875785351962267	0.962420337807702	58	HSD17B13,APOC3,NSMAF,LDLR,CYP17A1,FGF1,ABHD6,SIRT4,MTOR,CREB1,TNF
GO:0050434	positive regulation of viral transcription	GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION	-0.203610461534842	-0.740968114213281	0.876977970834626	0.963075146361197	33	POLR2H,SNW1,MDFIC,POLR2K,GTF2F1
GO:0002720	positive regulation of cytokine production involved in immune response	GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	0.213327329860512	0.722844848330661	0.877315534424431	0.963075146361197	28	RSAD2,XCL1,GPRC5B,PRKCZ,MALT1,CD36,TNFRSF14,TNFSF4,TLR4
GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	GO_MODULATION_OF_TRANSCRIPTION_IN_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION	-0.2184541568526	-0.716191287696759	0.87735002516907	0.963075146361197	22	CCL3,SNW1
GO:0061418	regulation of transcription from rna polymerase ii promoter in response to hypoxia	GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_HYPOXIA	0.212157186537739	0.725097638399114	0.877525690401008	0.963075146361197	29	EPAS1,CREBBP,EGLN1,EP300,VEGFA,CUL2,SIRT2,UBE2D1,CITED2,HIF1AN,UBE2D3,BACH1,EPO,HIF3A,TCEB1,UBE2D2
GO:0009651	response to salt stress	GO_RESPONSE_TO_SALT_STRESS	-0.224062374476232	-0.705696556313835	0.87823102654329	0.963535083228395	19	AQP1,HIF1A,BDKRB2,BAX,HSP90AA1
GO:0001782	b cell homeostasis	GO_B_CELL_HOMEOSTASIS	-0.223860637776185	-0.705061175675575	0.878969546896042	0.963984884644449	19	HIF1A,CASP3,BAX,SPNS2,ABL1,BCL2,TNFRSF13C
GO:0043542	endothelial cell migration	GO_ENDOTHELIAL_CELL_MIGRATION	-0.190703075472457	-0.76670098387737	0.879417361362813	0.963984884644449	51	SCG2,DPP4,KDR,TGFBR1,FAP
GO:0051651	maintenance of location in cell	GO_MAINTENANCE_OF_LOCATION_IN_CELL	-0.178428467999434	-0.803400584077008	0.87961238299578	0.963984884644449	91	EZR,MORC3,KDELR3,ARL2BP,GAA,TSPO,SPTBN4,TWF1,KDELR2,TBCCD1,HK2,SORL1,KEAP1,SCIN,PSMD10
GO:0009991	response to extracellular stimulus	GO_RESPONSE_TO_EXTRACELLULAR_STIMULUS	0.164438754239496	0.871355470569817	0.879786561386734	0.963984884644449	416	TK1,CHAT,TSHB,PPARD,TPH2,BMP8A,AKT2,CLPS,RRAGB,ADRB1,TXN2,ATG14,RRAGD,HSD11B2,ADRB2,PPARA,ULK1,MIOS,LRRK2,VLDLR,OTC,APOC3,TSC1,CCND1,FADS1,CYP17A1,MAX,GHSR,TYR,MTHFR,PCSK9,GIPR,FNIP1,HMGCR,PTEN,CYP27B1,PRKAA2,NPRL3,PIK3C3,SIRT5,UCN,RRP8,ADIPOR2,STC2,SETDB1,PSPH,GCK,SLC8A1,TGFBR2,KAT2A,ERCC1,LIPG,ACAT1,ALAD,COX4I1,ADA,MMP7,ESR2,MOG,SLC34A3,MTOR,WDR59,FOXO1,ADSSL1,RNF152,IL4,HMGCS2,DEPDC5,GSS,RXRA,MYH13,HMGCS1,NPY,TIMP3,P2RX7,CYBA,SOD1,USF2,MAP1LC3A,WNT11,IMPACT,SLC38A3,NMUR2,ADORA2B,MKKS
GO:0035265	organ growth	GO_ORGAN_GROWTH	0.188684295649336	0.768000224329014	0.881222938941416	0.965244520819006	64	AGT,NDRG4,ESR1,BMP10,SMAD1,PTEN,PRKAR1A,TGFBR2,AGTR2,SHH,S1PR1,NKX2-5,RXRA,SOX9,PLAG1,NLGN4X,PSAPL1,TGFBR3,DDR2,SPRY2,FOXC2,RARB,MYOCD
NA	modulation of growth of symbiont involved in interaction with host	GO_MODULATION_OF_GROWTH_OF_SYMBIONT_INVOLVED_IN_INTERACTION_WITH_HOST	0.236110571466672	0.689899748383202	0.882018399776972	0.96556145463255	16	LBP,TNF,CD36,OSBP,IRF8
GO:0090201	negative regulation of release of cytochrome c from mitochondria	GO_NEGATIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA	0.233006486027352	0.69219508626084	0.882085999107276	0.96556145463255	17	PARL,PPIF,FXN,OPA1
GO:1901184	regulation of erbb signaling pathway	GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY	-0.181237724389324	-0.78809275397794	0.882486662027372	0.965577278923212	75	GPRC5A,HAP1,EPGN,PTPN2,RHBDF1,STAM2,ERRFI1,EGFR,UBA52,PLAUR,RNF126
GO:0034035	purine ribonucleoside bisphosphate metabolic process	GO_PURINE_RIBONUCLEOSIDE_BISPHOSPHATE_METABOLIC_PROCESS	-0.225154764899434	-0.699207735112088	0.882674179217683	0.965577278923212	18	PAPSS2,SULT2A1,SULT4A1,SLC35B3,HDDC3,SULT2B1,SULT1E1,SULT1C2,SLC35B2,ABHD14B,ENPP1,SLC26A1,SULT1B1
GO:0042100	b cell proliferation	GO_B_CELL_PROLIFERATION	-0.200229984707396	-0.739301943423934	0.883223684210526	0.965864496768236	35	RAG2,IFNA14,IFNE,IFNA16,BAX,ABL1,IL10,BCL2
GO:0007214	gamma aminobutyric acid signaling pathway	GO_GAMMA_AMINOBUTYRIC_ACID_SIGNALING_PATHWAY	0.220938934612425	0.703740080634646	0.883559499917144	0.965917920338131	22	PLCL1,GABBR1,GABRA3
GO:0045124	regulation of bone resorption	GO_REGULATION_OF_BONE_RESORPTION	-0.206482668512282	-0.727595127619018	0.884219838549154	0.966088445361161	29	TNFSF11,TNFRSF11B,IAPP,CLDN18,CARTPT,FSHB,PTGER4
GO:0014075	response to amine	GO_RESPONSE_TO_AMINE	-0.191512228829252	-0.75660576102654	0.884289512821668	0.966088445361161	47	ASS1,DRD5,GRIN2A,CNR2,CPS1,RRM2B,SLC18A2,HMBS,HNMT
GO:0000154	rrna modification	GO_RRNA_MODIFICATION	0.220456220913971	0.702202529194609	0.884774723352544	0.966304905517411	22	FTSJ3,TFB2M,EMG1,METTL16,NSUN4,METTL15,NSUN3,MRM1,NAT10,DKC1,NOP58
GO:0032481	positive regulation of type i interferon production	GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION	0.186623077853828	0.770986797932757	0.885452079406739	0.966534000238592	69	LRRFIP1,DDX3X,CREBBP,ZBTB20,HSPD1,DDX58,POLR3F,EP300,IRF1,TMEM173,NFKB1,HMGB1,POLR3K,PRKDC,POLR3H,MRE11A,TLR4,FLOT1
GO:0090344	negative regulation of cell aging	GO_NEGATIVE_REGULATION_OF_CELL_AGING	0.23174844848245	0.688457819450119	0.885954471060854	0.966534000238592	17	FZR1,PTEN,MARCH5,PRKDC,BCL6,TWIST1,CDK6,BCL2L12,TERT,ZKSCAN3
GO:0070207	protein homotrimerization	GO_PROTEIN_HOMOTRIMERIZATION	-0.221750275999423	-0.69841447721976	0.88607237499457	0.966534000238592	19	MGST1,SKIL,MIF,SCARA5,NELL2,ALOX5AP
NA	regulation of protein complex disassembly	GO_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY	0.170803087781077	0.831632058227417	0.886135508155583	0.966534000238592	196	CEP192,SPTB,SPAG5,TUBGCP5,WDR62,BIRC8,MAP1A,CLASP1,SBDS,TUBGCP2,ARHGEF2,GOLGA2,LMOD1,LMOD3,DYNC1H1,ADD1,FAM21C,GPSM2,SMC1A,MAP4,CAPZB,TMOD1,SETX,KIFC1,TNF,SEMA5A,TUBG1,RGS14,NCOR1,HDAC6,APC,TUBGCP6,RDX,CFL2,GAS2L2,TPR,HAUS8,TUBGCP3,CKAP5,UVRAG,ESPL1,CAPG,EML1,SPTBN1,NES,ACTN2,CHMP1B,STARD9,CLASP2,SYNJ1,BNIP3,KPNB1,CHMP4B,MLH1,PLK1,CHMP4C,NEK7,KIF23,UPF1,KIF3B,PPP2R1A,RNF4,PARP3,BIRC3,LZTS2,ETF1,PSRC1,DSTN
GO:0031163	metallo sulfur cluster assembly	GO_METALLO_SULFUR_CLUSTER_ASSEMBLY	0.228521677078926	0.689447987098516	0.887219859999629	0.966534000238592	18	CIAO1,NFS1,FXN,MMS19,CIAPIN1,NARFL,FAM96B,ISCU
GO:0034661	ncrna catabolic process	GO_NCRNA_CATABOLIC_PROCESS	0.219779350555072	0.70004654522652	0.887315645081107	0.966534000238592	22	ZCCHC11,EXOSC4,EXOSC7,LIN28B,EXOSC3,SLFN14,DIS3L2
GO:1901983	regulation of protein acetylation	GO_REGULATION_OF_PROTEIN_ACETYLATION	0.189620945827552	0.758853802998004	0.887400370054085	0.966534000238592	59	SMARCB1,FLCN,HDAC2,KLF15,KAT2A,EP300,TERF2IP,PARK7,SPI1,WBP2,HDAC5,GATA2,TWIST1,PAXIP1,MYOCD,SIN3A,PPARGC1A,RPS6KA5,FOXP3,MAPK3,PIWIL2,MECP2,CTCF,TGFB1,SOX4,NAP1L2,KAT2B,SET,IL1B
GO:0044843	cell cycle g1 s phase transition	GO_CELL_CYCLE_G1_S_PHASE_TRANSITION	-0.17499801423944	-0.80262948329213	0.887795603089721	0.966534000238592	101	ID4,RBBP8,RPA3,ORC4,MCM5,CDKN2C,ACVR1,CDKN1A,TYMS,RPA2,BCAT1,FBXO5,DHFR,MCM2,E2F4,CDC25A,BRD4,ACVR1B,CUL1,CDT1,INHBA,CDC6,RPS6,PCNA,EIF4EBP1,POLE2,DBF4
GO:0030813	positive regulation of nucleotide catabolic process	GO_POSITIVE_REGULATION_OF_NUCLEOTIDE_CATABOLIC_PROCESS	-0.231595565266913	-0.682272945871655	0.887821137155596	0.966534000238592	15	GPD1,HIF1A,RAPGEF3,HTR2A,ARNT,IGF1
GO:0034637	cellular carbohydrate biosynthetic process	GO_CELLULAR_CARBOHYDRATE_BIOSYNTHETIC_PROCESS	0.194996845634956	0.744349265475375	0.888393499208975	0.966534000238592	47	AKT2,PGM5,PHKG1,GYS1,IMPA2,GCK,HAS3,GYG1,GOT1,EPM2A,PRKAG3,PHKG2,PPP1R3C,ISYNA1,CSGALNACT1,UGP2,B3GNT3,AGL,HAS2,AKR1B1
GO:0051785	positive regulation of nuclear division	GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION	0.191191814882348	0.754415518637	0.888454675231977	0.966534000238592	55	LRP5,PDGFB,GOLGA2,PTEN,GORASP1,TGFA,ANAPC11,DLGAP5,PRDM9,FGF8,UBE2B,EGF,ESPL1,MSX1,EREG,NSMCE2,SIRT2,PLK1
NA	positive regulation of transcription factor import into nucleus	GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FACTOR_IMPORT_INTO_NUCLEUS	0.193519770869229	0.748566178109594	0.888729309540052	0.966534000238592	50	PIK3R1,RBCK1,C8orf4,AKAP6,DDX58,CSF3,PPP3R1,IL18R1,TNF,TMEM173,SMAD3,TLR4,EDA,PRKCQ,PIK3R2,SPPL3,PPP3CB,TRIM28,MAVS,CHERP
GO:0030514	negative regulation of bmp signaling pathway	GO_NEGATIVE_REGULATION_OF_BMP_SIGNALING_PATHWAY	0.199048848687327	0.73751135058498	0.888746387283237	0.966534000238592	41	VWC2,HFE2,BMPER,HIPK2,VWC2L,DAND5
GO:0072330	monocarboxylic acid biosynthetic process	GO_MONOCARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS	-0.169374379072653	-0.829581800004085	0.889004534978812	0.966534000238592	153	PTGIS,SHMT1,LIPC,RDH10,ALOX15,PKLR,ABCB11,XBP1,ALOX12B,TBXAS1,AKR1C3,DECR2,LPL,STAR,RBP1,PLA2G4F,GGT1,AGXT,FASN,PTGS1,DCN,PECR,ABAT,CYP7A1,ACSM3,MIF,DEGS1,EDN1,FCER1A,AGMO,HSD3B7,DSEL,ACACA,HSD17B12,ACSF3,ACSM1,SRR,ALOX5AP,CYP8B1,FADS6,VCAN,ALOXE3,CYP46A1,LDHC,PTGES,GGT6
GO:0018023	peptidyl lysine trimethylation	GO_PEPTIDYL_LYSINE_TRIMETHYLATION	0.230366073183028	0.684351181021541	0.889934533551555	0.967232689678571	17	SUV39H1,TET2,SETD3,HIST1H1D,OGT,SETD2,SETD4,SUV39H2,ARID4B
GO:0030217	t cell differentiation	GO_T_CELL_DIFFERENTIATION	0.176044274726083	0.799387071660217	0.891219296455059	0.967535717566769	119	RC3H2,RSAD2,ATP7A,STAT5B,LFNG,TSC1,SPN,CHD7,CD8A,DNAJA3,SHH,DLL4,IRF1,IL18R1,IL4,PATZ1,TNFSF8,RHOH,IL2,HMGB1,JMJD6,PRKDC,ITPKB,FOXN1,SATB1
GO:0010800	positive regulation of peptidyl threonine phosphorylation	GO_POSITIVE_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION	-0.212582339067706	-0.705098126671794	0.891593503072871	0.967535717566769	23	CHI3L1,WNT5A,RIPK2
GO:0046632	alpha beta t cell differentiation	GO_ALPHA_BETA_T_CELL_DIFFERENTIATION	-0.192618966125638	-0.745686165728873	0.891606897947254	0.967535717566769	43	GATA3,ANXA1,PLA2G2D,FUT7,IRF4,RPL22,NKX2-3,SEMA4A,PTGER4,ABL1,BCL2,ZAP70,PAX1
GO:0032892	positive regulation of organic acid transport	GO_POSITIVE_REGULATION_OF_ORGANIC_ACID_TRANSPORT	0.208294793923139	0.711896993117562	0.892547502144669	0.967535717566769	29	P2RY2,SLC6A1,RAB3GAP1,GABBR1,P2RX7,SLC38A3,DPYSL2,TMEM27,OXT
GO:0050688	regulation of defense response to virus	GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS	-0.166998701757236	-0.836560794280731	0.893037767657197	0.967535717566769	178	SNRPB2,TARBP2,TRAF3IP1,CPA3,TRAF3IP2,ALPK1,LENG9,FGF7,HTRA1,ANXA5,IL27,MB21D1,TMEM39A,ATP6V1H,APOBEC3F,HCAR1,FGFBP1,UBA52,MSTN,PHYHIP,AP1S3,ZCCHC17,HPR,TRIM38,SLC25A19,LMCD1,EIF2AK4,YIPF1,HIST1H3C,FABP1
GO:0001522	pseudouridine synthesis	GO_PSEUDOURIDINE_SYNTHESIS	-0.223680716263895	-0.684083680147381	0.893217112947182	0.967535717566769	17	NOP10,NHP2,PUS7,RPUSD4,PUSL1,GAR1,TRUB2,RPUSD2,PUS7L,PUS3,RPUSD1,DKC1,RPUSD3,TRUB1,PUS10,PUS1,NAF1
GO:0030902	hindbrain development	GO_HINDBRAIN_DEVELOPMENT	0.174193774334325	0.804018258066686	0.893277822908205	0.967535717566769	133	HERC1,ATP7A,NRXN1,DLC1,LRP6,SCN5A,KDM2B,GLI2,NFIB,RERE,SMAD1,OGDH,CLP1,AGTR2,KAT2A,EZH2,SHH,ESR2,MYO16,CBLN1,NCOR1,CNTN1,HOXB3,LDB1,SMAD9,NCOA1,LHX1,UQCRQ,NLGN4X,PROX1,GATA2,TRNP1,HES3,ASCL1,SEC24B,SMO,PHOX2B,WLS,EN1,KLHL1,AGTPBP1,PPARGC1A
GO:1903008	organelle disassembly	GO_ORGANELLE_DISASSEMBLY	0.171025198012457	0.819324388443387	0.893362603735302	0.967535717566769	173	DPF3,MARK2,OBSCN,MYOM1,MAP1A,ATG14,ATPIF1,USP30,ACIN1,KIF5B,SLC6A1,NDUFB9,GOLGA2,PINK1,MTIF3,WIPI2,MDH1,DZANK1,PI4K2A,MYLK,PFKP,LSM4,HBS1L,ADAMTS7,ATG9A,HDAC6,CDK1,CD93,REP15,MAP1LC3A,ZNF189,ITPKC,GBF1,CA7,WDR45,PRKG1,FAM13B,CAPS,KLC1,FCGR3B,MBD5,CALCB,EIF2S1,RIMS3,AMBRA1
GO:0000725	recombinational repair	GO_RECOMBINATIONAL_REPAIR	0.185850246168152	0.759046514001465	0.893492480473915	0.967535717566769	65	ZSWIM7,ZFYVE26,DMC1,UBE2N,EXD2,RAD21L1,FBXO18,LIG3,ERCC4,MMS22L,RECQL5,RAD51AP1,HUS1,SFPQ
GO:0042104	positive regulation of activated t cell proliferation	GO_POSITIVE_REGULATION_OF_ACTIVATED_T_CELL_PROLIFERATION	0.211764811667275	0.704163300202612	0.893727424411889	0.967535717566769	26	STAT5B,HHLA2,IL4,TMIGD2,IL2,HMGB1,TNFSF4,JAK3,IL12RB1
NA	regulation of transcription from rna polymerase i promoter	GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER	-0.213667865143341	-0.700499664008135	0.893874067102931	0.967535717566769	22	POLR2K,EIF2AK3,RASL11A,UBTF,DHX33,H2AFY2
GO:0002701	negative regulation of production of molecular mediator of immune response	GO_NEGATIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	-0.207810172933517	-0.712273274993817	0.893891736137079	0.967535717566769	26	APOA2,ANGPT1,IRAK3,CUEDC2,IL10,IL13RA2,IFNA2,HMOX1,C10orf54,THOC1
GO:0032480	negative regulation of type i interferon production	GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION	0.201431927826304	0.724507737408694	0.893950113378685	0.967535717566769	36	PIN1,PCBP2,HERC5,DDX58,UBA7,TRAIP,REL,LILRB1,PPM1B,IFIH1,MAVS,TNFAIP3,TBK1,NLRC5,NMI,ITCH,TRAF3
GO:0060795	cell fate commitment involved in formation of primary germ layer	GO_CELL_FATE_COMMITMENT_INVOLVED_IN_FORMATION_OF_PRIMARY_GERM_LAYER	0.208799906036202	0.707503986989774	0.894687757154613	0.968022819216466	28	PAF1,SMAD1,SOX2,EYA1
GO:1904292	regulation of erad pathway	GO_REGULATION_OF_ERAD_PATHWAY	0.209814061818738	0.70424346808784	0.895903155504276	0.968651022386806	27	EDEM2,USP13,DERL3,SGTA,YOD1,BAG6,USP14,UBXN1
GO:0030834	regulation of actin filament depolymerization	GO_REGULATION_OF_ACTIN_FILAMENT_DEPOLYMERIZATION	0.195973751794989	0.734125609324141	0.896028815848717	0.968651022386806	43	SPTB,LMOD1,LMOD3,ADD1,FAM21C,CAPZB,TMOD1,SEMA5A,RDX,CFL2,CAPG,SPTBN1,ACTN2
GO:0032733	positive regulation of interleukin 10 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_10_PRODUCTION	-0.204340423524049	-0.713920972632553	0.89613169450758	0.968651022386806	28	PYCARD,IRF4,HGF,TLR9,CD34,PTGER4,IL20RB,CD46
GO:0098732	macromolecule deacylation	GO_MACROMOLECULE_DEACYLATION	0.185148671761999	0.756181155368464	0.896824697191417	0.968784868192907	65	HDAC9,HDAC2,HDAC4,REST,SIRT4,SIRT5,PHF21A,HDAC6,BRMS1,SFPQ,MSL3P1,HDAC11,BAZ2A,MTA1,HDAC5,SAP30,PER1,SIRT2,SIN3A,ATXN3,LYPLA1,MTA3
GO:0042026	protein refolding	GO_PROTEIN_REFOLDING	0.231154646107932	0.67541885649953	0.89683114952142	0.968784868192907	16	HSPD1,DNAJB2,DNAJA2
GO:1904029	regulation of cyclin dependent protein kinase activity	GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY	-0.175305367915214	-0.790846995499018	0.898056532930314	0.969797333924747	92	CDKN2B,CCNG1,SFN,HEXIM1,CDKN2C,MEN1,CEBPA,PIM1,CDKN1A,EGFR,CASP3,CCNA2,PSMD10,GTF2H1,CDC25A,DNAJC3,PKD2,CCNB3
GO:1903573	negative regulation of response to endoplasmic reticulum stress	GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS	-0.197700033113107	-0.724648034437855	0.898369830764447	0.969824519035641	34	CREB3L1,TXNDC12,XBP1,USP25,MAGEA3,ERLEC1
GO:0036092	phosphatidylinositol 3 phosphate biosynthetic process	GO_PHOSPHATIDYLINOSITOL_3_PHOSPHATE_BIOSYNTHETIC_PROCESS	0.191732097404923	0.738468321609068	0.898750561797753	0.969840893196018	49	PIK3C2B,PIK3R1,FGF1,PIK3R3,PIK3C3,IRS1,PIKFYVE,FGFR1,PIK3C2G,GAB1,FGF6,FGF8,PIK3R2,PIK3CB,GRB2,SYNJ1,PIK3CG,PIK3C2A
GO:0016051	carbohydrate biosynthetic process	GO_CARBOHYDRATE_BIOSYNTHETIC_PROCESS	0.175559112880245	0.792333500667047	0.899075053756101	0.969840893196018	115	AKT2,PGM5,ST8SIA6,NDST1,PGAM2,PGAM1,PHKG1,GYS1,SLC25A11,IMPA2,CHST13,GCK,MDH2,HAS3,B3GALT2,MDH1,GOT2,ALDOC,ALDOA,ENO2,GYG1,GOT1,CRTC2,EPM2A,PRKAG3,PHKG2,SLC25A12,CHST9,SLC25A10,B3GALNT1,PPP1R3C,GPI,B3GALT1,TKT,ISYNA1
GO:0018345	protein palmitoylation	GO_PROTEIN_PALMITOYLATION	-0.211878766585731	-0.69463419173582	0.899476921056663	0.969840893196018	22	ZDHHC20,GOLGA7,MAP6D1,ZDHHC8,ZDHHC3,ZDHHC23,ZDHHC1,ZDHHC6
GO:0002227	innate immune response in mucosa	GO_INNATE_IMMUNE_RESPONSE_IN_MUCOSA	-0.217802106594597	-0.685979504327759	0.899582953212564	0.969840893196018	19	HIST1H2BE,HIST1H2BK,HIST1H2BF,FAU,CAMP,LTF
GO:0006368	transcription elongation from rna polymerase ii promoter	GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER	-0.178928523529439	-0.774189540917722	0.899902795778559	0.969840893196018	73	TAF9B,POLR2H,LEO1,SSRP1,TBP,POLR2K,TAF10,ELP4,GTF2H2,TAF4B,GTF2F1,GTF2H1
GO:0031668	cellular response to extracellular stimulus	GO_CELLULAR_RESPONSE_TO_EXTRACELLULAR_STIMULUS	-0.166336482385855	-0.83068972075552	0.900383814564885	0.969840893196018	174	CDKN2B,GSDMD,DAP,ALDOB,SFRP2,WNT2B,SLC38A2,GAS2L1,ATF3,XBP1,PIM1,AKR1C3,TBL2,SH3GLB1,CDKN1A,EIF2AK3,PPM1D,LEP,USP33,PPARG,PCK1,EIF2AK4,KCNB1,PICK1,FOXA3,MYOD1,KIAA1324,RRAGC,CPEB4,CARTPT,WNT9B,MDM2,BHLHA15,SLC2A1,NFE2L2,IFI16,SIRT1,SLC39A4,PAWR,ATP2B1,BCL2,PIK3R4,JUN,GABARAPL1,SEH1L,NR4A2,ZFYVE1,GAS6,HMOX1,FOS,GBA,FGF23,PMAIP1,FOLR2,NR1H4,ALB,UCN3,DAPL1,MAP1LC3C,GLUL,MYBBP1A,WNT4,NUDT1,RRAGA,COL1A1,ATF4,SLC1A2,INHBB,CADPS2,TNC,ADNP
GO:0002718	regulation of cytokine production involved in immune response	GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	0.189366086243736	0.741731147484055	0.900503913369787	0.969840893196018	53	TRPM4,RSAD2,XCL1,GPRC5B,PRKCZ,TNF,MALT1,CD36,BTK,CLC,LILRB1,BCL6,TNFRSF14,TNFSF4,TLR4,TGFB3
GO:0000731	dna synthesis involved in dna repair	GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR	-0.181527954645446	-0.764828807698555	0.90096045327867	0.969840893196018	64	RBBP8,RPA3,POLH,UBA52,RPA2,KIAA0101,ZBTB1,XRCC2,BARD1,RAD51B,UBB,SIRT1,NBN,PCNA,POLE2
GO:0072337	modified amino acid transport	GO_MODIFIED_AMINO_ACID_TRANSPORT	-0.207561538200353	-0.696826735798272	0.900978155978595	0.969840893196018	24	PDPN,SLC38A2,SLC1A4,FOLR3,SLC7A9,SLC16A2
GO:0032886	regulation of microtubule based process	GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS	0.16789617847871	0.827377963897076	0.901325165031368	0.969904253675059	215	CEP192,SPAG5,TUBGCP5,WDR62,BIRC8,NPM1,MAP1A,CLASP1,TBCD,PAFAH1B1,DIXDC1,ROCK2,SBDS,CLIP1,TUBGCP2,ARHGEF2,GOLGA2,MACF1,INPP5J,DYNC1H1,GSK3B,CAV3,CHORDC1,GPSM2,EPHA3,SMC1A,CEP85,MAP4,KIFC1,TUBG1,PLK4,CDKN1B,RGS14,NCOR1,HDAC6
GO:0044839	cell cycle g2 m phase transition	GO_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.173563160025034	0.79925770915781	0.901614077875447	0.969905077062561	131	FBXL7,CEP192,NDE1,PRKACA,CLASP1,PAFAH1B1,AKAP8,CALM3,PPP1R12B,HMMR,DYNC1H1,BTRC,LATS1,CALM1,KHDRBS1,TUBG1,PLK4,CDK1,PPP1R12A,DCTN1,GADD45A,CDC25C,PPP1CB
GO:0042130	negative regulation of t cell proliferation	GO_NEGATIVE_REGULATION_OF_T_CELL_PROLIFERATION	-0.186337551374371	-0.74914986881092	0.901911924610366	0.969906174743899	51	BMP4,TNFRSF21,CEBPB,HLA-DRB5,PLA2G2D,CASP3,LILRB2,IL2RA,HLA-DRB1,DLG1,PLA2G2F,PAWR,IL20RB,CD276,IL10
GO:0042769	dna damage response detection of dna damage	GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE	-0.196857257618188	-0.721558932244758	0.902389730378004	0.969906174743899	34	RPA3,UBA52,RPA2,RPS3,UBB,PCNA,USP1,POLD1,RFC1,MRPS11,RPS27A,CUL4B,RFC4,RFC2,RAD18,MRPS35,DNAJA1
GO:0006997	nucleus organization	GO_NUCLEUS_ORGANIZATION	0.173865566148598	0.792490872106636	0.902752044059902	0.969906174743899	122	LPIN1,POM121,SUN1,PAFAH1B1,VPS4A,DMPK,HIPK2,NUP85,RAE1,PRM1,CHMP7,PSME4,SUN5,HIST1H2BA,NUP188,NEK9,EMD,CDK1,ATXN7,BANF1,ETS1,LEMD2,SYNE2,DMRTC2,CHMP6,SUMO1,TPR,AAAS,PARP11,POM121C,UBXN2B,AKAP8L,RRN3,CTDNEP1,NUP214,CHMP1B,CHMP4B,PLK1,CHMP4C,NUP35
GO:0042180	cellular ketone metabolic process	GO_CELLULAR_KETONE_METABOLIC_PROCESS	0.185696194882462	0.748327294566018	0.903106889034614	0.969906174743899	61	STAT5B,HAGH,CYP17A1,CYP2B6,HMGCR,COQ9,IDO1,GOT2,PARK7,NDUFA9,AKR7A2,SCP2,ADM,GLO1,COQ2,HSD17B3,GPI,ADH4,COQ5,CRYZL1,COQ7,STARD3,HSD17B1,PDSS2,AKR1B1,LHB,COQ4,KYNU
GO:0070536	protein k63 linked deubiquitination	GO_PROTEIN_K63_LINKED_DEUBIQUITINATION	0.212834398634889	0.686231025186282	0.903144630983432	0.969906174743899	23	ZRANB1,USP13,YOD1,OTUD7A,SHMT2,BABAM1,ATXN3,USP20,TNFAIP3,BRE,USP8,OTUD5,OTUD7B,PSMD14,CYLD
GO:1901214	regulation of neuron death	GO_REGULATION_OF_NEURON_DEATH	-0.163288796561165	-0.848118332638755	0.903343986281082	0.969906174743899	233	GDF5,BBC3,TYRO3,CCL3,DLX1,TOX3,MAP2K4,ANGPT1,KRAS,GATA3,CEBPB,PRKCI,SARM1,SNCA,CLCF1,CTNNB1,NONO,STAT3,TP73,NR4A3,STAR,HIF1A,CASP3,CDK5,C5AR1,IKBKG,SORL1,GRID2,NQO1,PAK3,GDNF,KCNB1,CD34,XRCC2,STXBP1,MAP3K11,BAX,GRIK2,CPEB4,F2R,CLN3,ALKBH1,LRP1,BTG2,FOXO3,CDC42,UBB,ABL1,NAE1,TRIM2,SIRT1,PAWR,PSEN1,SERPINF1,GABRB2,MAP3K12,BCL2,UBE2V2,ISL1,HRAS,ITSN1,JUN,PTPN5,PICALM,SIGMAR1,NR4A2,PTK2B,MAP3K5
GO:0021591	ventricular system development	GO_VENTRICULAR_SYSTEM_DEVELOPMENT	0.209936790845848	0.691175465784457	0.903929089207392	0.970224908887781	25	KDM2B,KIF27,RAPGEF2,NME5,SEMA6D,UCHL5,CDK6,MECP2
GO:0097028	dendritic cell differentiation	GO_DENDRITIC_CELL_DIFFERENTIATION	-0.198027523649941	-0.715125753375816	0.904814708034863	0.970865893288284	32	CCL19,BATF3,PRTN3,IRF4,TNFSF9
GO:0001832	blastocyst growth	GO_BLASTOCYST_GROWTH	-0.221256248796633	-0.664819351138934	0.906595666385263	0.971749745590817	16	GINS4,SALL4,RAD51B,NBN,NCAPG2,UBTFL1
GO:2000678	negative regulation of transcription regulatory region dna binding	GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING	0.224585793163705	0.66717963573624	0.906840499925606	0.971749745590817	17	PPARA,LHX2,HEY2,MSX1,ANKRD33,SIN3A
GO:0090224	regulation of spindle organization	GO_REGULATION_OF_SPINDLE_ORGANIZATION	0.221557579853595	0.668437364056812	0.907365802031305	0.971749745590817	18	TPR,CHMP1B,CHMP4B,PLK1,CHMP4C,RNF4,PARP3,PSRC1,VPS4B,PKD1
GO:0007032	endosome organization	GO_ENDOSOME_ORGANIZATION	0.1859306188491	0.741614014936195	0.907395212245261	0.971749745590817	58	ALS2,VPS4A,ARFGEF2,VPS11,CHMP7,PIK3C3,VPS37B,TMEM127,VPS37C,FASLG,CHMP6,TSG101,VPS37A,CLCN3,CHMP1B,CHMP4B,CHMP4C,STX6,VPS33B,VPS4B,AKTIP,STAM
NA	regulation of catenin import into nucleus	GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS	0.207755283434907	0.690830761098824	0.907479051687783	0.971749745590817	26	RGS20,UBR5,SEMA5A,EMD,KANK1,SMAD3,BAMBI,EGF
GO:0009074	aromatic amino acid family catabolic process	GO_AROMATIC_AMINO_ACID_FAMILY_CATABOLIC_PROCESS	-0.220981176752277	-0.66399282886424	0.907483169902808	0.971749745590817	16	GSTZ1,TAT
GO:0080171	lytic vacuole organization	GO_LYTIC_VACUOLE_ORGANIZATION	0.190770422698215	0.728216005481822	0.90784553430174	0.971749745590817	47	LRRK2,ARF1,SYT7,VPS11,CLN8,MBTPS1,P2RX7,TFEB,GNPTAB,TMEM175,ATP6V0C,MT3,CLN6,TMEM165,RAB14,RAB20,AKTIP,NAGLU
GO:1902186	regulation of viral release from host cell	GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL	0.203794236870816	0.696515269107288	0.908609706682242	0.971749745590817	29	VPS4A,TRIM26,VPS37B,TRIM13,TRIM32,TRIM31,ZNF502,VAPB,TSG101,CHMP4B,CHMP4C,TRIM8,TRIM28
GO:0045010	actin nucleation	GO_ACTIN_NUCLEATION	-0.210276483671753	-0.680762763538766	0.908684170322355	0.971749745590817	21	ARPC5,ACTR3,SCIN
GO:0009649	entrainment of circadian clock	GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK	0.210911419614321	0.680030862650715	0.908802027846148	0.971749745590817	23	NR2F6,USP2,PPP1CB,MTA1,PER1,PPP1CC,CRY2,GNA11
GO:0051647	nucleus localization	GO_NUCLEUS_LOCALIZATION	0.220996425493714	0.666744366049722	0.908814081734965	0.971749745590817	18	PAFAH1B1,CAV3,TMEM201,SYNE2
GO:0072593	reactive oxygen species metabolic process	GO_REACTIVE_OXYGEN_SPECIES_METABOLIC_PROCESS	0.17721264648351	0.77165620967858	0.909442603611887	0.971946545726431	93	ATP7A,PDGFB,ATPIF1,LRRK2,NNT,NDUFS1,PRDX2,SOD2,HBA1,PARK7,P2RX7,CYBA,SOD1,TPO,CCS,RFK,MAOB,GBF1,NDUFA13,PRDX3,CYP1A1,DDIT4,NOX4,SPR,PRDX5,MT3,SOD3,BNIP3,NOS2,HBB,NOX3,PXDNL,PRDX6
GO:0002699	positive regulation of immune effector process	GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	-0.16749799444201	-0.81440391855156	0.909575644396393	0.971946545726431	145	C3,RBP4,CCL19,RARA,FFAR3,WNT5A,KLK7,GATA3,FOXF1,MZB1,RPS19,ANXA1,CLCF1,XBP1,NR4A3,RIPK2,VAMP8,WHSC1,ZBTB1,KLK5,NLRP3,IL5
GO:0043555	regulation of translation in response to stress	GO_REGULATION_OF_TRANSLATION_IN_RESPONSE_TO_STRESS	-0.215126521496571	-0.668065487867174	0.911799761620977	0.973805876696706	18	EIF2AK3,EIF2AK4,RPS6KA1,DNAJC3,PPP1CA
NA	 de novo protein folding	GO__DE_NOVO_PROTEIN_FOLDING	0.227871018014881	0.654779958951459	0.911894273127753	0.973805876696706	15	HSPD1,CHCHD4,HSPA14,HSPH1,UGGT1,ENTPD5,TOR1B
GO:0018146	keratan sulfate biosynthetic process	GO_KERATAN_SULFATE_BIOSYNTHETIC_PROCESS	0.204989556469675	0.688049956797982	0.912459022398037	0.974099926860701	27	ACAN,ST3GAL6,ST3GAL3,ST3GAL2
GO:2000036	regulation of stem cell population maintenance	GO_REGULATION_OF_STEM_CELL_POPULATION_MAINTENANCE	0.222074941434057	0.659720619211749	0.913610325844368	0.974926866193944	17	KDM2B,YAP1,CNOT1,SMO,ZNF706
GO:0032469	endoplasmic reticulum calcium ion homeostasis	GO_ENDOPLASMIC_RETICULUM_CALCIUM_ION_HOMEOSTASIS	0.216875856710247	0.663665562848366	0.913812912311912	0.974926866193944	19	ITPR1,APP,GRINA,ATP2A2,BAK1,ATP2A1,WFS1
GO:0042440	pigment metabolic process	GO_PIGMENT_METABOLIC_PROCESS	0.185535212889151	0.732095377322125	0.915364025695931	0.976272278356307	55	COX15,CECR1,ATPIF1,PPAT,TYR,COX10,ALAD,ADA
GO:1900024	regulation of substrate adhesion dependent cell spreading	GO_REGULATION_OF_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING	-0.189689148311765	-0.718259195608096	0.91583471370372	0.976391543082583	39	S100A10,EFNA5,ITGB1BP1,CALR,TRIOBP
GO:0090503	rna phosphodiester bond hydrolysis exonucleolytic	GO_RNA_PHOSPHODIESTER_BOND_HYDROLYSIS_EXONUCLEOLYTIC	0.199114574750351	0.691759297335879	0.916055999125014	0.976391543082583	31	DCP2,EXOSC4,EXOSC7,PAN2,CNOT6L,EXOSC3,CNOT8,ISG20L2,CNOT1,DIS3L2
GO:0042129	regulation of t cell proliferation	GO_REGULATION_OF_T_CELL_PROLIFERATION	-0.166473522816845	-0.80767700463323	0.916468015040181	0.976521474715178	143	CD55,CCL19,IL18,BMP4,TNFRSF21,CEBPB,HLA-DRB5,IL27,ANXA1,PLA2G2D,CTNNB1,IL6ST,PYCARD,RIPK2,RIPK3,CASP3,LEP,TNFSF9,LILRB2
GO:0055094	response to lipoprotein particle	GO_RESPONSE_TO_LIPOPROTEIN_PARTICLE	0.217588243289353	0.65646190886449	0.917596598399465	0.976768480748184	18	CDH13,ITGB2,HMGCS1,NPC1,CD36,SIGLEC15,CCL5
GO:0032479	regulation of type i interferon production	GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION	0.174020182697973	0.774771867428696	0.917601128233352	0.976768480748184	106	LRRFIP1,DDX3X,PIN1,CREBBP,ZBTB20,PCBP2,HERC5,HSPD1,DDX58,POLR3F,EP300,UBA7,IRF1,TMEM173,TRIM32,TRAIP,NFKB1,HMGB1,POLR3K,PRKDC,REL,POLR3H,LILRB1,MRE11A,TLR4,FLOT1
GO:0048566	embryonic digestive tract development	GO_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT	0.20090137973494	0.686628241890905	0.917936736817128	0.976768480748184	29	HLX,GLI2,SHH,ADA,TCF21,TNF,VPS52,SIX2,RARB,PDGFRA,OVOL2,SCT
GO:0002040	sprouting angiogenesis	GO_SPROUTING_ANGIOGENESIS	0.191579671574022	0.709836722286853	0.918190028901734	0.976768480748184	41	NRP1,RNF213,BMPER,E2F8,CDH13,SEMA5A,TEK,VEGFA,JMJD6,SRF,PGF,GPLD1,CCBE1,EFNB2,E2F7
GO:0031110	regulation of microtubule polymerization or depolymerization	GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION	0.168497882272596	0.798525903952328	0.918471806366358	0.976768480748184	160	CEP192,SPAG5,TUBGCP5,WDR62,BIRC8,MAP1A,CLASP1,TBCD,SBDS,CLIP1,TUBGCP2,ARHGEF2,GOLGA2,INPP5J,DYNC1H1,CAV3,GPSM2,SMC1A,MAP4,KIFC1,TUBG1,CDKN1B,RGS14,NCOR1,HDAC6,APC,TUBGCP6,GAS2L2,TPR,HAUS8,TUBGCP3,CKAP5,UVRAG,ESPL1,EML1,MAPRE1,CHMP1B,STARD9,CLASP2,KPNB1,CHMP4B,MLH1,SKA2,PLK1,CHMP4C,NEK7,KIF23,KIF3B,PPP2R1A,RNF4,MAPT,PARP3
GO:0001945	lymph vessel development	GO_LYMPH_VESSEL_DEVELOPMENT	-0.208261666164327	-0.665513191651741	0.91923763108655	0.976768480748184	20	PDPN
GO:0006206	pyrimidine nucleobase metabolic process	GO_PYRIMIDINE_NUCLEOBASE_METABOLIC_PROCESS	0.219654032323636	0.652528796275452	0.919468829043297	0.976768480748184	17	UCKL1,TET2,MTOR,MAPK1,CAD,DHODH,UMPS
GO:0033006	regulation of mast cell activation involved in immune response	GO_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	-0.194625427065634	-0.697134935610221	0.919524189261031	0.976768480748184	31	FOXF1,VAMP8,PDPK1,FCER1A,IL4R,ZAP70,IL13RA2,SNX6,FES,HMOX1,VAMP7,FER,C12orf4,STXBP2,CD84
GO:0045672	positive regulation of osteoclast differentiation	GO_POSITIVE_REGULATION_OF_OSTEOCLAST_DIFFERENTIATION	0.208904969951957	0.665409203030983	0.91964795345326	0.976768480748184	22	GNAS,CREB1,TNF,CA2,IL17A,ATP6AP1
GO:1904030	negative regulation of cyclin dependent protein kinase activity	GO_NEGATIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY	0.198015149298372	0.687939698599384	0.920011666484378	0.976768480748184	31	CDK5RAP1,PTEN,LATS1,FBXO31,CDKN1B,APC,HEXIM2,NR2F2,MYOCD,PLK1,CDKN2A,FBXO7,TNFAIP3,INCA1
GO:1901984	negative regulation of protein acetylation	GO_NEGATIVE_REGULATION_OF_PROTEIN_ACETYLATION	-0.211817549646367	-0.657789628442371	0.920294723155271	0.976768480748184	18	NOC2L,SNCA
GO:0000226	microtubule cytoskeleton organization	GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION	0.162978177556158	0.837195167347083	0.920314092762487	0.976768480748184	308	BRSK1,CEP192,NDE1,SPAG5,TUBGCP5,WDR62,DNAI2,BIRC8,NPM1,MAP1A,CLASP1,TUBE1,CENPA,PAFAH1B1,VPS4A,ROCK2,SBDS,KATNAL1,C2CD3,ZMYND10,CLIP1,TUBGCP2,ARHGEF2,GOLGA2,IFT172,EYA1,FIGNL2,DYNC1H1,RP1,PEX14,CAV3,OBSL1,SPIRE1,NIN,GPSM2,SMC1A,ULK4,MAP4,DST,PRKCZ,KIFC1,TUBG1,PLK4,RGS14,NCOR1,CEP68,CDK1,PPP1R12A,ATXN7,DNAI1,PAX6,GADD45A,MAP7D1,TUBGCP6,MAP1S,CUL9,CEP57L1,HTT,TRDN,GAS2L2,HAUS8,BCAS3,TUBGCP3,SPAG1,GAS2L3,CKAP5,KATNAL2,UBE2B,UVRAG
GO:0032098	regulation of appetite	GO_REGULATION_OF_APPETITE	0.206810701056121	0.666809126323113	0.920502553175857	0.976768480748184	23	PPARA,GHSR,UCN,NPY,MKKS,NPFF,GCG
NA	regulation of cgmp biosynthetic process	GO_REGULATION_OF_CGMP_BIOSYNTHETIC_PROCESS	-0.204499499999027	-0.670441626507797	0.92103477708958	0.976768480748184	22	NPR1,OSTN,GUCA1A,HPCA,PTK2B,GUCA2A,APOE,PDZD3,RCVRN
GO:0031648	protein destabilization	GO_PROTEIN_DESTABILIZATION	-0.193991839283028	-0.694865467613723	0.921052631578947	0.976768480748184	31	BMP2,SNCA,XBP1,SIRT6,MDM2,MYLIP,RNF139,SIRT1
GO:0048821	erythrocyte development	GO_ERYTHROCYTE_DEVELOPMENT	-0.204321610075733	-0.669858423079363	0.921494386202972	0.976929166601324	22	EPB42,L3MBTL3,SOX6,RPS6,ARID4A
GO:0006278	rna dependent dna biosynthetic process	GO_RNA_DEPENDENT_DNA_BIOSYNTHETIC_PROCESS	0.211486595126552	0.656476601077568	0.921946706143597	0.977100948639593	20	HMBOX1,ACD,TERF2IP,MRE11A,WRAP53,ATM,DKC1,TERT
GO:0042113	b cell activation	GO_B_CELL_ACTIVATION	0.170794983880055	0.775550935868647	0.92306252976798	0.977739079793031	119	PIK3R1,HDAC9,ITFG2,LFNG,MFNG,HSPD1,FNIP1,HDAC4,CD40,ERCC1,LAX1,LAT2,EP300,ADA,AICDA,IL4,EXOSC3,IL11,MALT1,BTK,PRKDC,BCL6,RNF168,IFNA21,TLR4,HDAC5,BAK1,LYL1,MEF2C,IFNA4,IKZF3,JAK3
GO:0035264	multicellular organism growth	GO_MULTICELLULAR_ORGANISM_GROWTH	0.179040472225431	0.739661149997601	0.923129766958482	0.977739079793031	69	GNAS,RC3H2,SP2,NDUFS6,ADD1,KAT2A,ERCC1,STK40,WDTC1,SLC4A10,MTOR,FLVCR1,FKBP8,ATRX,GIGYF2,PLAG1,BRCA2,APBA2,SMO,RARB,PALB2,EN1,RMI1,ANKRD11
GO:0032570	response to progesterone	GO_RESPONSE_TO_PROGESTERONE	0.186328280209288	0.711259292730889	0.924493024593701	0.97850946896474	47	CATSPERG,BAD,CATSPER2,ADRB2,ABHD2
GO:1902107	positive regulation of leukocyte differentiation	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	-0.167336165161764	-0.791532538627663	0.925242270419935	0.97850946896474	122	PRKCA,TNFSF11,CCL19,RARA,GATA3,ANXA1,XBP1,RIPK2,RIPK1,CSF1,IL36B,IL20,TNFSF9,LILRB2,RAG1,ZBTB1,ATP11C,SLC9B2,NLRP3,IL5,SART1,NKAP,IL2RA,TESC,TRIB1,IL4R,CD46,PF4,MMP14,ZAP70,PRDM1,JUN
GO:0007339	binding of sperm to zona pellucida	GO_BINDING_OF_SPERM_TO_ZONA_PELLUCIDA	0.194439284096058	0.685475231320924	0.925601311953353	0.97850946896474	33	ZP2,ZPBP,TCP1,UBAP2L,FETUB,CCT3,OVGP1,ZP3,CCT7,CCT4,ZPBP2,ACR,PRSS37,GLIPR1L1,CCT8,POMZP3,CRISP1
GO:1901985	positive regulation of protein acetylation	GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION	-0.18928820598401	-0.698902008885981	0.925942389758179	0.97850946896474	35	TADA2A,GATA3,MUC1,XBP1
NA	positive regulation of homeostatic process	GO_POSITIVE_REGULATION_OF_HOMEOSTATIC_PROCESS	0.165449706066723	0.806698410591439	0.925958317519513	0.97850946896474	198	SMARCB1,AGT,BAD,TRPM4,HMBOX1,CALM3,RYR2,CAPN3,XCL1,DRD2,ADCYAP1R1,CXCL11,AKAP6,OBFC1,INPP5D,CXCR3,MAP3K4,AGTR2,ANO1,ERCC1,MAPKAPK5,CALM1,TCP1,STX4,ACD,CCR2,TNF,MAPK1,CA2,P2RX7,ETS1,NPC1,CCT3,CXCL9,ATRX,PLCG1,HTT,ATP6AP1,TRDN,CA7,JPH2,MRE11A,SLC27A1,MED1,CCT7,GATA2,BAK1,WRAP53,CCT4,PRKCQ,GCG,PKIB,P2RX2,TMEM27,CASQ2,MAP2K7,CD4,PPARGC1A,GPLD1,OXT,PPP3CB,NEK7,METRNL,GSTO1,DRD3,ATM,CCL5,MAPK3,CCT8,HLA-DRB3,ACVR2A,PDX1,NPSR1,ATR,DHX36,TNKS,AKAP5
GO:0048002	antigen processing and presentation of peptide antigen	GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN	-0.163211121180399	-0.812219506883385	0.926203235338308	0.97850946896474	170	KIF2C,CTSE,KIF18A,AZGP1,KIF5A,HLA-DRB5,CALR,KIF3A,CANX,SEC24D,NCF4,BCAP31,SEC24A,SEC13,AP1S3,MARCH1,PSMB11,DYNC2LI1,PSMD10,KIF4A,DYNLL1,KIF3C,SPTBN2,PSMD5,PSMD13,PSMB5,SEC31A,DYNC1I1,HLA-DRB1,ACTR1B,PSMA6,PSMA4,DYNC2H1,ABCB5,SH3GL2,AP1S2,PSMC3,KIF2B,HLA-DRA,AP1M1
GO:0021988	olfactory lobe development	GO_OLFACTORY_LOBE_DEVELOPMENT	-0.19081971605543	-0.694420729143677	0.926355214751119	0.97850946896474	33	WNT5A,SEMA3A,SLIT3,FEZF1,ROBO2,EXT1
GO:0051782	negative regulation of cell division	GO_NEGATIVE_REGULATION_OF_CELL_DIVISION	0.182020443916861	0.723305081790218	0.926726598173516	0.97850946896474	57	AURKAIP1,CSNK2A1,VPS4A,MAD2L1,OSM,PRKAR1A,E2F8,NME6,PTCH1,APC,ATRX,KLHL22,TPR,MAD1L1,TOM1L2
GO:0002637	regulation of immunoglobulin production	GO_REGULATION_OF_IMMUNOGLOBULIN_PRODUCTION	0.187476955288214	0.705740525948495	0.926735704637551	0.97850946896474	44	UNG,XCL1,CD40,STX4,IL4,TNF,EXOSC3,PKN1,IL2,PRKDC,BCL6,TNFSF4
GO:0070233	negative regulation of t cell apoptotic process	GO_NEGATIVE_REGULATION_OF_T_CELL_APOPTOTIC_PROCESS	0.219093912419047	0.640178176314853	0.926902704209646	0.97850946896474	16	IDO1,SLC46A2,ADA,PIP,PRKCQ,JAK3
GO:0051445	regulation of meiotic cell cycle	GO_REGULATION_OF_MEIOTIC_CELL_CYCLE	-0.186012912870137	-0.708332774915068	0.927054871220605	0.97850946896474	40	WNT5A,DMRT1,CALR,MSX2,FBXO5,CDC20,NPM2,MOS,NANOS2,FBXO43,RPS6KA2,DUSP1,ASPM,STRA8
GO:0032303	regulation of icosanoid secretion	GO_REGULATION_OF_ICOSANOID_SECRETION	-0.205180535639096	-0.655667246175997	0.927374787868239	0.978540293405797	20	TNFSF11,CYP4F2,MIF,EDN1
GO:0071216	cellular response to biotic stimulus	GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS	-0.164499152170399	-0.803131119731452	0.927855661960707	0.978740883158803	149	ASS1,CCL3,RARA,IL18,WNT5A,ENTPD2,LY96,CEBPB,TSPO,IRAK1,XBP1,PYCARD,RIPK2,STAR,HIF1A,EIF2AK3,LILRB2,ABCA1,NR1H3,EDNRB,IL24,NLRP3,ADAM9,HMGB2
GO:0048515	spermatid differentiation	GO_SPERMATID_DIFFERENTIATION	0.169901660740407	0.771494507622057	0.928386745594339	0.978994293756436	119	PRKACA,NSUN2,PAFAH1B1,TDRD5,DMC1,DLD,DPY19L2,FABP9,QKI,ABHD2,PRM1,CELF1,INSL6,PSME4,HIST1H2BA,ACRBP,SPO11
GO:0007338	single fertilization	GO_SINGLE_FERTILIZATION	-0.168659448381065	-0.772053061050546	0.929211746522411	0.97930037184076	100	ZAN,ZP1,TARBP2,OR10J1,T,TNP2,PKDREJ,MST1R,ADAM30,ATP8B3,SERPINA5,PLCD4,SYT6,IZUMO1,ELSPBP1,ASTL,STX2,NPM2,AKAP4,CCT5,GNPDA1,CLGN,FOXL2,CATSPER1,CD46
GO:0045619	regulation of lymphocyte differentiation	GO_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	-0.166396289011771	-0.790759301834786	0.929258879280864	0.97930037184076	126	CCL19,RARA,CYP26B1,BMP4,PTPN2,GATA3,IL27,ANXA1,XBP1,RIPK2,IL36B,IRF4,TNFSF9,LILRB2,RAG1,ZBTB1,ATP11C,FAS,PGLYRP1,PRELID1,NLRP3,SART1
GO:0009620	response to fungus	GO_RESPONSE_TO_FUNGUS	0.184202295070945	0.706383791867263	0.929976622909549	0.979750019628651	48	VIP,APP,CLEC6A,DCD,HAMP,NPY,MALT1,IL17A,GNLY,PTX3,TLR4,BAK1,ADM
GO:0006879	cellular iron ion homeostasis	GO_CELLULAR_IRON_ION_HOMEOSTASIS	0.186329136686394	0.697996490610826	0.930535794687078	0.979950692833067	43	HFE2,FTMT,HAMP,FLVCR1,SOD1,FXN,HEPH,ABCG2,HMOX2,IREB2,TTC7A,TMPRSS6,ABCB7,TFR2
GO:0007173	epidermal growth factor receptor signaling pathway	GO_EPIDERMAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	-0.179235989382634	-0.720598810823827	0.930749365712215	0.979950692833067	51	EFEMP1,AREG,KRAS,EGFR,GRB7,PIGR,PDPK1,SHC3,RASSF2,ABL1,REPS2,HRAS,ARF4,PTK2B,NRAS,FES
NA	clathrin mediated endocytosis	GO_CLATHRIN_MEDIATED_ENDOCYTOSIS	0.192105391762622	0.677247339541863	0.932051749271137	0.980833813325333	33	STON2,FNBP1L,OPHN1,SYT12,AP2M1,PIP5K1C,HIP1R,INPP5F,PACSIN1,SYNJ1,FCHO1
GO:0072348	sulfur compound transport	GO_SULFUR_COMPOUND_TRANSPORT	0.194739465565258	0.671165394044527	0.932291191653138	0.980833813325333	30	SLC26A4,MFSD3,SLC5A6,SLC26A5,SLC38A7,SLC26A7,SLC26A3,C2orf83
GO:1904950	negative regulation of establishment of protein localization	GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION	0.164647824902726	0.800972877732367	0.932546374367622	0.980833813325333	195	RSAD2,BMP8A,PYDC2,PDE8B,DRD4,LRRK2,AKAP1,RANGAP1,DRD2,GHSR,SP100,SERGEF,HMGCR,SUFU,PKIA,PDE4C,GSK3B,REST,SIAH3,SIRT4,CABP1,IRS1,PDE2A,DERL3,HADH,CX3CL1,MTOR,GBP1,YOD1,TNF,EMD,PARK7,PPFIA1,BAG4
GO:0022613	ribonucleoprotein complex biogenesis	GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS	-0.156437804908331	-0.858781095745748	0.933093284207001	0.980833813325333	378	RPL24,NOC2L,RPL38,TARBP2,RBFA,RPL35,GEMIN8,RPL30,SNRPF,RPL9,RPL3,RPS3A,RPS19,XRN2,RPS27,PRMT5,RPL4,RPS11,RSL24D1,RPL7A,EIF3H,RPS4Y1,NVL,WDR75,WDR46,RPS8,EIF3L,RPL18,NOC4L,NLE1,EXOSC2,NOP10,EXOSC6,RPS24,RPL18A,UBA52,RPL15,EIF2D,RPS16,WDR43,BRIX1,RPP25,CDC123,RPL5,RPS27L,GRB7,EXOSC5,NSA2,RPL10A,RPS3,SNRPE,RPL22,RPS29,RPL26,RPL19,DENR,EIF4H,KRR1,SART1,GEMIN6,EXOSC10,RPS28,GNL2,SNRPB,RPS5,MINA,RPS17,DROSHA,EXOSC8,WDR36,PES1,DHX37,NHP2,RPF2,DDX21,PAPD5,RPL36,GNL1,CNOT7,RPS6,DDX51,RPP21,SIRT1,TGS1,RPL23A,EIF3G,RPP30,RPS18,FAU,TXNL4B,SF3A3,RPL32,BOP1,RPLP0,RPL14,NOP14,RPS15,SNRPG,RAN,RRP36,RIOK3,PNO1,RPS13,THUMPD1,RPL28,RPS4X,FAM103A1,RPL34,NOL11
GO:0071322	cellular response to carbohydrate stimulus	GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS	-0.173121865864706	-0.740667877261643	0.933103559945409	0.980833813325333	69	CMA1,COLEC12,SLC2A5,XBP1,MEN1,STAR,HIF1A,LEP,FAS,KCNB1,IL1R1
GO:0032814	regulation of natural killer cell activation	GO_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION	-0.194594035002265	-0.666974713743522	0.933660339176913	0.980833813325333	26	IL18,LEP,ZBTB1,PGLYRP1,PGLYRP2,BLOC1S3,GAS6,IL23R,PGLYRP3
GO:0043112	receptor metabolic process	GO_RECEPTOR_METABOLIC_PROCESS	-0.17199332547617	-0.749665175464934	0.933680466770497	0.980833813325333	76	EZR,RAB31,SNX25,SNCA,FUT8,FAM109A,SH3GLB1,HTR1B,GTF2H2,CDK5,PPARG,CAPN1,SCYL2,LMBRD1,IL10,NRG1,CD81,PIK3R4,PICALM,EHD3,FAM109B,LDLRAP1,CALCA,FNTA
GO:0042035	regulation of cytokine biosynthetic process	GO_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS	0.172442846274244	0.749640128751992	0.934246812939034	0.980833813325333	92	MAPKAPK2,STAT5B,TRIB2,SPN,GHSR,IL9,LBP,INPP5D,TIA1,PRG2,IRF1,CCR2,SIGIRR,IL4,TNF,HSPB1,ASB1,PTAFR,NFKB1,CD80,LILRB1,FOXJ1,TLR4,PRKCQ,IL21,MAST2,TICAM1,EREG
GO:0048857	neural nucleus development	GO_NEURAL_NUCLEUS_DEVELOPMENT	0.17794520374481	0.721905112532051	0.934269225322192	0.980833813325333	63	CALM3,S100A1,CKB,NFIB,CALM1,GLUD1,SYPL2,MAOB,MAPKAP1,PLP1,SEC16A,ASCL1,SEC24B,ATP5F1,COX6B1,PHOX2B,SIRT2,RAD1,ZNF148,CASP5,CDK5R2,PHOX2A,CACNA1A,MBP,TTBK1,KCNC1
GO:0006369	termination of rna polymerase ii transcription	GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION	0.17923608446055	0.714911793662731	0.934502091305509	0.980833813325333	58	NCBP1,CLP1,DDX39B,SRSF4,CPSF1,SETX,MAZ,NCBP2,RNPS1,MED18,SRSF1,DHX38,RBM8A,CHTOP
GO:0072665	protein localization to vacuole	GO_PROTEIN_LOCALIZATION_TO_VACUOLE	-0.182397391471697	-0.702794203366855	0.935002914667504	0.980991101422012	42	AP3M1,VPS25,SH3GLB1,SNF8,SORL1,GCC2,SNX16,CD81,SH3BP4,PIK3R4,VPS41,RAB35,HGS
GO:0000038	very long chain fatty acid metabolic process	GO_VERY_LONG_CHAIN_FATTY_ACID_METABOLIC_PROCESS	0.201160015422963	0.648589910726771	0.935527717570993	0.980991101422012	23	SLC27A5,ACOT2,SLC27A6,ACADVL,ELOVL7,CYP4F12,PEX2
GO:0007623	circadian rhythm	GO_CIRCADIAN_RHYTHM	-0.164836583908071	-0.786523436347644	0.935616973485033	0.980991101422012	129	MC3R,TPH1,LIPC,ID4,PAX4,PRMT5,F7,NONO,HCRTR2,DDC,HDAC3,ARNTL2,STAR,ADIPOQ,TYMS,LEP,NAMPT,FAS,TIMELESS,CARTPT,ATP7B,AHR,PPP1CA
GO:0045879	negative regulation of smoothened signaling pathway	GO_NEGATIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY	-0.194827826021853	-0.660880297600368	0.935817714398717	0.980991101422012	25	TRAF3IP1,RFX4,KIF7,KCTD11,TULP3,GLIS2
GO:0021762	substantia nigra development	GO_SUBSTANTIA_NIGRA_DEVELOPMENT	0.184471651981002	0.691038277693708	0.936497073390365	0.98100116562904	43	CALM3,S100A1,CKB,CALM1,GLUD1,SYPL2,MAOB,MAPKAP1,PLP1,SEC16A,ATP5F1,COX6B1,SIRT2,RAD1,ZNF148
GO:0000188	inactivation of mapk activity	GO_INACTIVATION_OF_MAPK_ACTIVITY	-0.195508844523929	-0.656363366404602	0.936507588384946	0.98100116562904	24	DUSP18,RGS4
GO:0071156	regulation of cell cycle arrest	GO_REGULATION_OF_CELL_CYCLE_ARREST	-0.167373980603267	-0.764851345951703	0.936701647751555	0.98100116562904	99	SFN,FOXM1,FAP,MUC1,CNOT6,TP73,CDKN1A,UBA52,CCNB1,CDK5,RNF112,CHEK2,BAX,E2F4,TRIAP1,INSM1,PKD2,BTG2,MDM2,MIF,UBB,CNOT7,PCNA
GO:0045621	positive regulation of lymphocyte differentiation	GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	-0.170673446002482	-0.745757492810267	0.937850217396359	0.981898547980138	77	CCL19,RARA,GATA3,ANXA1,XBP1,RIPK2,IL36B,TNFSF9,LILRB2,RAG1,ZBTB1,ATP11C,NLRP3,SART1,NKAP,IL2RA,IL4R,CD46,MMP14,ZAP70,PRDM1
GO:1902743	regulation of lamellipodium organization	GO_REGULATION_OF_LAMELLIPODIUM_ORGANIZATION	0.189924165663304	0.669557656503048	0.938556851311953	0.982153204217975	33	SSH2,HDAC4,CAPZB,MTOR,SSH1,KANK1,PLXNB3
GO:0044770	cell cycle phase transition	GO_CELL_CYCLE_PHASE_TRANSITION	0.162211525238087	0.808300487884376	0.938677022569586	0.982153204217975	235	FBXL7,CUL4A,RPA4,CEP192,NDE1,ORC2,PRKACA,CLASP1,MCM4,PAFAH1B1,AKAP8,CALM3,CAMK2A,PPAT,PPP1R12B,CCND1,MCM7,HMMR,ORC6,DYNC1H1,POLA2,BTRC,CHMP7,LATS1,CALM1,CAMK2G,KHDRBS1,CCNE2,TUBG1,PLK4,CDKN1B,CDK1,PPP1R12A,DCTN1,ORC3,GADD45A,CDC25C,CCNA1,PPP1CB,CUL2
GO:0007266	rho protein signal transduction	GO_RHO_PROTEIN_SIGNAL_TRANSDUCTION	0.183638881388881	0.687918685336222	0.939000450247636	0.982186300663003	43	GNA12,ROCK2,MYO9B,CFL1,LIMK1,CDH13,C15orf62,PTH,BCL6
GO:0061515	myeloid cell development	GO_MYELOID_CELL_DEVELOPMENT	0.184207284535373	0.686168136557666	0.940992779783393	0.983619687521805	42	PAFAH1B1,RHAG,EP300,FLVCR1,FLI1,C6orf25,LRRK1,JMJD6,BCL6,MED1,SRF,ABI1,MAEA,FOXP1,VPS33B,TAL1
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	GO_POSITIVE_REGULATION_OF_INSULIN_SECRETION_INVOLVED_IN_CELLULAR_RESPONSE_TO_GLUCOSE_STIMULUS	0.193021088969795	0.654038560704908	0.941135594770047	0.983619687521805	28	BAD,TRPM4,ANO1,STX4,GCG,TMEM27,GPLD1,PPP3CB,HLA-DRB3,PDX1,PLA2G6,RFX6,HLA-DRB4,FAM132A,OXCT1
GO:0034660	ncrna metabolic process	GO_NCRNA_METABOLIC_PROCESS	0.158322202027476	0.847467685117	0.941247478760467	0.983619687521805	467	TARS2,NOL6,ADAR,ELL3,METTL3,NSUN2,CDK5RAP1,NOL9,ZBTB8OS,NPM3,BRF1,PARS2,GTF3C5,ELAC2,ALKBH8,RPL3L,KIAA0391,NCBP1,GTF3C1,ZCCHC11,SBDS,CTU1,SNAPC3,ELL,MRTO4,TARBP1,EARS2,SUV39H1,SMAD1,LRRC47,TRMT2B,CHD7,WDR12,LARS2,INTS2,EXOSC4,TYW5,ABT1,ZC3H8,EXOSC7,HENMT1,TUT1,RCL1,METTL1,CLP1,RRP8,TRPT1,LIN28B,MARS,METTL2B,IARS2,OSGEP,TAF1B,RPL35A,CPSF1,DDX47,AIMP2,POLR2I,INTS3,TRMT1L,RPRD1A,WARS,NCBP2,SRRT,TSR2,RPL29,RPS14,HNRNPA2B1,EXOSC3,DDX49,NOP2,FTSJ3,PELP1,DICER1,PLD6,GTF2H5,TDRKH,TRMT1,TFB2M,DUS1L,POU2F1,LSM6,SMAD3,MRPL39,YBEY,DUS4L,IMP3,TAF6,EMG1,METTL16,MARS2,NAF1,RRP7A,GTF2F2,QRSL1,TARS,ISG20L2,POLR2C,PUS1,URM1,NSUN4,SARS2,RPRD1B,SLFN14,RPP14,C2orf49,SNAPC4,WBP11,RPL10
GO:0003407	neural retina development	GO_NEURAL_RETINA_DEVELOPMENT	0.180011859805149	0.693327083880438	0.942813483146067	0.984950398593936	49	PTPRM,PROM1,HIPK2,RPE65,RP1,SMARCD3,GNAT2,TSPAN12,SOX9,CABP4,SDK1,LHX1
GO:0046638	positive regulation of alpha beta t cell differentiation	GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	-0.181951579870801	-0.680536713843139	0.94455489779962	0.98646347688288	37	CCL19,RARA,ANXA1,RIPK2,NLRP3,NKAP
GO:0045061	thymic t cell selection	GO_THYMIC_T_CELL_SELECTION	-0.199564459723723	-0.628539049980486	0.945327772709501	0.986649756922617	19	GATA3,FAS,ZAP70,AIRE,CD3E,CCR7,DOCK2,GLI3
GO:0042744	hydrogen peroxide catabolic process	GO_HYDROGEN_PEROXIDE_CATABOLIC_PROCESS	0.203214711775961	0.621860856785215	0.945574827662886	0.986649756922617	19	PRDX2,HBA1,TPO,PRDX3,PRDX5,HBB,PXDNL,PRDX6
GO:0010799	regulation of peptidyl threonine phosphorylation	GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION	0.186571963276674	0.662337431481608	0.94561263096624	0.986649756922617	34	CALM3,GSK3B,CALM1,MAPK1,SMAD7,EGF,DDIT4,GCG,TRPC6,UBE2K,SPRY2,SIRT2,PLK1,PPP1R15A,OGT,CAB39,S1PR2,TGFB1,PRKAG2,CALM2,SPHK1,SPRED1
GO:0000732	strand displacement	GO_STRAND_DISPLACEMENT	-0.193953509149998	-0.635867110394099	0.946247619881377	0.986804432400421	22	RBBP8,XRCC2,BARD1,RAD51B,NBN
GO:0060563	neuroepithelial cell differentiation	GO_NEUROEPITHELIAL_CELL_DIFFERENTIATION	0.175645169755587	0.702923426869072	0.946359948761742	0.986804432400421	59	MREG,C10orf11,PAFAH1B1,CDH2,USP13,POU4F3,FGFR1,SOD1,WNT11,MITF,FGF8,TYRP1,MEF2C,ASCL1,SEC24B
GO:0033683	nucleotide excision repair dna incision	GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION	0.18450547383893	0.663626887917348	0.946757369614513	0.986804432400421	36	CUL4A,ERCC1,GTF2H3,POLD2,ERCC4,RFC3,GTF2H5,POLK,FAN1,NTHL1,OGG1
GO:0014002	astrocyte development	GO_ASTROCYTE_DEVELOPMENT	0.204766628845877	0.617779205401067	0.946933546242828	0.986804432400421	18	EIF2B5,LAMB2,TLR4,PLP1,MT3,SMO,NF1,CDK6
GO:0042088	t helper 1 type immune response	GO_T_HELPER_1_TYPE_IMMUNE_RESPONSE	-0.1957538279813	-0.625543611732596	0.947565380096602	0.987088707854548	20	IL18,HLA-DRB5
GO:0010762	regulation of fibroblast migration	GO_REGULATION_OF_FIBROBLAST_MIGRATION	-0.189884203259994	-0.644110912298522	0.947792841291116	0.987088707854548	25	ITGB1BP1,HAS1,CORO1C,THBS1,PRR5L,FGF2,RAC1,RCC2
GO:0097576	vacuole fusion	GO_VACUOLE_FUSION	-0.194876403900078	-0.622739748153277	0.949349462599539	0.987645641026964	20	VPS33A,VAMP8,LIX1,CLN3,SNAPIN,VPS41
GO:0050854	regulation of antigen receptor mediated signaling pathway	GO_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY	0.18313821564041	0.663337783046068	0.949399858790304	0.987645641026964	37	LGALS3,CEACAM1,PRKCH,CD300A,ADA,GBP1,DUSP3,MALT1
GO:0033194	response to hydroperoxide	GO_RESPONSE_TO_HYDROPEROXIDE	-0.206413714193521	-0.608088037820658	0.949418868904617	0.987645641026964	15	MGST1,CHUK,STX2
GO:1902106	negative regulation of leukocyte differentiation	GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	-0.16740343075383	-0.727935815861043	0.949501275806077	0.987645641026964	75	CCL3,RARA,BMP4,PTPN2,HOXA7,ANXA1,CTNNB1,TJP2,ADIPOQ,PGLYRP1,ZNF675,CLDN18,CARTPT,MAFB,MYC,TRIB1,INHBA,IL4R,PGLYRP2,GPR55,TLR3,LTF,TMEM176B,IFNA2,CALCA,GPR68
GO:0002793	positive regulation of peptide secretion	GO_POSITIVE_REGULATION_OF_PEPTIDE_SECRETION	0.169088397697305	0.730729992224195	0.950310559006211	0.98785715537025	89	BAD,PPARD,TRPM4,DRD2,GIPR,GJA1,JAK2,UCN,PFKM,GCK,ANO1,STX4,GLUD1,GABBR1
GO:0010501	rna secondary structure unwinding	GO_RNA_SECONDARY_STRUCTURE_UNWINDING	0.182523301518973	0.665218144096685	0.950601669497344	0.98785715537025	38	DDX3X,DDX17,DDX39B,DDX47,DDX55,DDX49,DDX42,DDX24,DDX54,DDX20,DDX23
GO:0036260	rna capping	GO_RNA_CAPPING	0.184384693174788	0.654572541002904	0.950742142025611	0.98785715537025	34	NCBP1,METTL1,GTF2H3,POLR2I,NCBP2,GTF2H5,GTF2F2,POLR2C,POLR2G,WDR4,POLR2L
GO:0038061	nik nf kappab signaling	GO_NIK_NF_KAPPAB_SIGNALING	0.170221496470548	0.722103075307312	0.950878545276177	0.98785715537025	80	PSMD11,PSMD2,PSMC6,BTRC,PSMC5,PSMB7,PSME4,UBE2M,TNFRSF10B,PSMA8,PSMD8,PSMB10,MALT1,PSMD3,PSMB1,NFKB1,PSMA5,CARD10,PSMB9,REL,PSMD6,PSMB3,PSMB6,PSMD1
GO:0000910	cytokinesis	GO_CYTOKINESIS	-0.166832147935521	-0.730599819994124	0.951720763333877	0.98842705627332	78	CUL7,KIF20A,CEP55,ACTR3,ANLN,KIAA0196,FMN2,KIF4A,ZNF365,AURKB,RALA,SNX33,AURKC,RHOA,GTPBP8,SPAST,STMN1,RAB11A,RHOC,RAB35,MYH10,RHOB,MYH9,PRC1,SNX18,ROPN1B,SEPT7
GO:0032743	positive regulation of interleukin 2 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION	-0.184087056692975	-0.648678392586576	0.952913856021232	0.988535773460065	29	ANXA1,RIPK2,IRF4,VTCN1,ABL1,CD276,PDE4B,MAP3K7,SASH3,IL1A,CD3E
GO:0042108	positive regulation of cytokine biosynthetic process	GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS	0.174186841104278	0.692176244824766	0.953035816210046	0.988535773460065	57	MAPKAPK2,STAT5B,SPN,IL9,LBP,IRF1,CCR2,IL4,TNF,HSPB1,PTAFR,CD80,TLR4,PRKCQ,IL21,TICAM1,EREG,CD4
NA	negative regulation of nf kappab import into nucleus	GO_NEGATIVE_REGULATION_OF_NF_KAPPAB_IMPORT_INTO_NUCLEUS	0.2057977731048	0.601327721164174	0.953127032803643	0.988535773460065	16	PYDC2,FAF1,LITAF,NFKBIA,PPM1B
GO:0043473	pigmentation	GO_PIGMENTATION	0.16950554350186	0.716061954736324	0.953175089778401	0.988535773460065	78	ATP7A,MREG,KIF13A,C10orf11,DRD2,ZEB2,TYR,USP13
GO:0043368	positive t cell selection	GO_POSITIVE_T_CELL_SELECTION	0.197549837093198	0.61321544053781	0.953293856402665	0.988535773460065	20	SHH,IL4,ITPKB,SRF,FOXP3,STK11,LY9,THEMIS
GO:0007229	integrin mediated signaling pathway	GO_INTEGRIN_MEDIATED_SIGNALING_PATHWAY	-0.16667439956153	-0.7264816390222	0.953741370092285	0.98869524229462	76	ITGA3,PRKD1,ITGB8,CTGF,ADAM15,ITGB1BP1,FUT8,ANGPTL3
GO:0048771	tissue remodeling	GO_TISSUE_REMODELING	0.168463423738913	0.71914877639497	0.954207142357957	0.988866549810398	83	LRP5,AGT,ATP7A,EPAS1,ADRB2,GJA1,AGTR2,DLL4,GJA5,CCR2,SPP2,NCDN,HMGB1,PTH,LRRK1,FGF8,TGFB3,AXL,BAK1,PTH1R,CSPG4,NOX4,MEF2C,ACE,IGFBP5,FOXC2,ARG1
GO:1903018	regulation of glycoprotein metabolic process	GO_REGULATION_OF_GLYCOPROTEIN_METABOLIC_PROCESS	-0.177557393326427	-0.667875899392541	0.954944464349695	0.988866549810398	38	CCL19,CTNNB1,CCL21,ABCA7,FKTN,TMEM59,ITM2B,PAWR,SOAT1,BCL2,TINF2
GO:0050654	chondroitin sulfate proteoglycan metabolic process	GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_METABOLIC_PROCESS	-0.176891170411178	-0.67359739526685	0.955610302351624	0.988866549810398	40	B3GALT6,SPOCK2,IDUA,DCN,CHST3,B3GAT1,DSEL,CYTL1,VCAN,CHPF,DSE,HEXA,NCAN,XYLT2,IMPAD1,HYAL4
GO:0032689	negative regulation of interferon gamma production	GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION	-0.179469192840023	-0.657824866216723	0.955670057300227	0.988866549810398	34	RARA,GATA3,HLA-DRB5,PGLYRP1,HLA-DRB1,INHBA,IL20RB,CD276,IL10,PGLYRP2
GO:0050851	antigen receptor mediated signaling pathway	GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY	0.160932788163979	0.77264425994311	0.956978522508146	0.988866549810398	176	CTLA4,PIK3R1,RBCK1,PSMD11,PSMD2,UBE2N,PSMC6,RNF31,BTRC,PTEN,INPP5D,PSMC5,PSMB7,PSME4,LAX1,LAT2,CD3G,IKBKB,PSMA8,SLA2,MAPK1,PSMD8,PSMB10,MALT1,PLCG1,PSMD3,PSMB1,CD38,NFKB1,PAG1,BTK,PSMA5,PSMB9,CD247,NFKBIA,TEC,PRKCQ,MEF2C,PSMD6,PSMB3,PIK3R2,PIK3CB,HLA-DQA1,PSMB6,PSMD1
GO:1903707	negative regulation of hemopoiesis	GO_NEGATIVE_REGULATION_OF_HEMOPOIESIS	-0.161639181102018	-0.753990297818204	0.957128758154202	0.988866549810398	112	CCL3,RARA,BMP4,PTPN2,HOXA7,HIST1H4C,LEO1,ANXA1,GAS2L1,CTNNB1,TJP2,ADIPOQ,HIST1H4D,PGLYRP1,ZNF675,CLDN18,HIST1H4E,CARTPT,HOXB8,MAFB,MYC,NFE2L2,TRIB1,INHBA,IL4R,PF4,PGLYRP2,GPR55,TLR3,KLF13,LTF,TMEM176B,PTK2B,IFNA2,CALCA,GPR68,MIXL1
GO:0030101	natural killer cell activation	GO_NATURAL_KILLER_CELL_ACTIVATION	0.174629700844787	0.675496292490647	0.95729058202578	0.988866549810398	50	UNC13D,STAT5B,KLRF2,VAMP2,IL18R1,ULBP1,ITGB2,IL2,IL21R,IFNA21,AXL,IFNA4
GO:0006301	postreplication repair	GO_POSTREPLICATION_REPAIR	0.176168111914195	0.666334315154276	0.957547084959796	0.988866549810398	45	UBE2N,WDR33,REV1,REV3L,POLD2,UBA7,RFC3,VCP,NPLOC4,POLK,UBE2B
GO:0050850	positive regulation of calcium mediated signaling	GO_POSITIVE_REGULATION_OF_CALCIUM_MEDIATED_SIGNALING	0.179782487654733	0.646639312655321	0.957569160997732	0.988866549810398	36	CALM3,AKAP6,CD8A,CALM1,ADA,CDH13,HTT,TRDN,JPH2,TREM2,P2RX2,CD4,SPPL3,GSTO1
GO:0030325	adrenal gland development	GO_ADRENAL_GLAND_DEVELOPMENT	0.191212470751932	0.609054623266689	0.957688129476533	0.988866549810398	22	CYP17A1,DKK3,WNT11,ASCL1,NR5A1,NR0B1,NF1,CITED2,THRA,INSR
GO:0030539	male genitalia development	GO_MALE_GENITALIA_DEVELOPMENT	-0.189774982562011	-0.614389870534013	0.957703136253519	0.988866549810398	21	WT1,CTNNB1,BMP5
GO:0000096	sulfur amino acid metabolic process	GO_SULFUR_AMINO_ACID_METABOLIC_PROCESS	0.179693778210191	0.646320243679288	0.957768707482993	0.988866549810398	36	MTR,MTHFR,NFS1,EIF2B4,SMS,NOX4,CTH,MUT,BHMT,CACNA1A,CNDP2,MTRR,DPEP1,GNMT,ENOPH1,BHMT2,MSRA,MTHFD2L,PCYOX1L
GO:0006699	bile acid biosynthetic process	GO_BILE_ACID_BIOSYNTHETIC_PROCESS	-0.192738848886893	-0.607041419806972	0.957926061079977	0.988866549810398	19	ABCB11,STAR,CYP7A1,HSD3B7,CYP8B1,CYP46A1,CYP39A1,SLC27A2,HSD17B4,CH25H
GO:0007274	neuromuscular synaptic transmission	GO_NEUROMUSCULAR_SYNAPTIC_TRANSMISSION	0.190953903837816	0.608231029628436	0.958019554049824	0.988866549810398	22	SLC5A7,RAB3A,P2RX2,ETV5,CACNA1A,DTNA,CHRNA6,EGR3
GO:2000209	regulation of anoikis	GO_REGULATION_OF_ANOIKIS	0.190654036958836	0.607275886335276	0.95851669090976	0.989076389209765	22	ZNF304,AES,BRMS1,CRYBA1,PTK2,PIK3CA,ITGA5,PTRH2,NOTCH1
GO:0009266	response to temperature stimulus	GO_RESPONSE_TO_TEMPERATURE_STIMULUS	0.161832059148101	0.750191767756817	0.959429991378873	0.989715400239438	137	HSPB7,EIF2B5,ADRB1,NR2F6,HDAC2,GMPR,ADRB2,TRPV2,HSPD1,C8orf4,OSM,CETN1,ABCC2,FGF1,DNAJB4,ACOT11,ANO1,DNAJA3,STAC,DNAJA2,FOXO1,HMGCS2,PDCD6,MICA
GO:0042693	muscle cell fate commitment	GO_MUSCLE_CELL_FATE_COMMITMENT	-0.200393639448168	-0.590353094899165	0.960132458931238	0.990136379128962	15	WT1,ACVR1
GO:2000278	regulation of dna biosynthetic process	GO_REGULATION_OF_DNA_BIOSYNTHETIC_PROCESS	0.165834248977484	0.718268339199974	0.960645374181559	0.990136379128962	90	HMBOX1,PDGFB,SMG6,PARM1,MCRS1,GJA1,GSK3B,OBFC1,MAP3K4,DDX39B,DACH1,MAPKAPK5,TCP1,ACD,RFC3,MAPK1
GO:2001022	positive regulation of response to dna damage stimulus	GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	-0.168286521263022	-0.68503968105266	0.960762484663971	0.990136379128962	54	FOXM1,SKIL,KDM4D,EGFR,CEBPG,RPS3,BRCC3,RNF8,MYC,SIRT1,PCNA,UBE2V2
GO:0071496	cellular response to external stimulus	GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS	0.1583245412495	0.793040426972129	0.961014720919287	0.990136379128962	247	AGT,BAD,RRAGB,TXN2,HABP4,ATG14,RRAGD,ULK1,MIOS,LRRK2,VLDLR,TSC1,FADS1,ATP1A2,KCNJ2,MAX,PCSK9,FNIP1,GJA1,HDAC4,BAG3,GSK3B,PRKAA2,NPRL3,PIK3C3,RRP8,GCK,CD40,PDE2A,TNFRSF10B,CASP8AP2,MMP7,IRF1,MTOR,WDR59,FOXO1,RNF152,DEPDC5,MYH13,P2RX7,CYBA,GADD45A,USF2,SOX9,MAP1LC3A,IMPACT,SLC38A3,ADORA2B,NFKB1,NCOA1
GO:0031952	regulation of protein autophosphorylation	GO_REGULATION_OF_PROTEIN_AUTOPHOSPHORYLATION	0.179268308257918	0.636409183632401	0.961583236321304	0.990418963726288	34	PDGFB,CALM3,CALM1,RAP2C,EPHA7,VEGFA,ENG,IMPACT,MRE11A,ACE,MOB1B,PPP2R5B,RAP2A,NEK10
GO:0006970	response to osmotic stress	GO_RESPONSE_TO_OSMOTIC_STRESS	0.169869715499224	0.684549000633505	0.961983588253017	0.990427918402933	61	DDX3X,AKT2,CAPN3,ARHGEF2,TACR3,SLC12A6,MYLK,TNF,KCNMA1,ATF2,PKN1,SLC2A4,APOBEC1,TSC22D2,TH,MAP2K7,HSP90AB1,SERPINB6,OXT,MARVELD3,PCP4,NFAT5
GO:0042339	keratan sulfate metabolic process	GO_KERATAN_SULFATE_METABOLIC_PROCESS	0.180892032659989	0.628450958767961	0.962466732290641	0.990427918402933	31	ACAN,ST3GAL6,ST3GAL3,ST3GAL2
GO:0036257	multivesicular body organization	GO_MULTIVESICULAR_BODY_ORGANIZATION	0.183136283137798	0.62054458233336	0.96289658955838	0.990427918402933	28	VPS4A,CHMP7,VPS37B,VPS37C,CHMP6,TSG101,VPS37A,CHMP1B,CHMP4B,CHMP4C
GO:0043302	positive regulation of leukocyte degranulation	GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DEGRANULATION	0.195224387751113	0.588990343883473	0.96292032604861	0.990427918402933	18	STX4,IL4,ADORA2B,PTAFR,AP1G1,GAB2
GO:0006457	protein folding	GO_PROTEIN_FOLDING	-0.155645439256727	-0.789620012947897	0.963063154168984	0.990427918402933	194	FKBP11,PPIB,APOA2,PPIL6,HSPA6,PDIA4,HSP90AB3P,PDIA6,AHSP,TXNDC2,CALR,FUT10,PFDN6,PPIL3,CANX,GNAI1,GNAT1,TOR1A,TTC9B,ERP44,ATF6,AIPL1,DNAJC1,PDIA5,HSPBP1,SIL1
GO:0006691	leukotriene metabolic process	GO_LEUKOTRIENE_METABOLIC_PROCESS	0.180929741805781	0.618370419783997	0.96541150272875	0.992539742878733	29	MAPKAPK2,PLA2G5,ABCC1,GGT7
GO:1901136	carbohydrate derivative catabolic process	GO_CARBOHYDRATE_DERIVATIVE_CATABOLIC_PROCESS	-0.155612295699126	-0.769174540972521	0.966758658412272	0.993474455120872	162	CHI3L1,AMDHD2,AGRN,MPG,NUDT18,DPYS,DUT,GPC5,FMOD,GPD1,SDC1,HPSE,APOBEC3F,PDE11A,IDUA,SMUG1,NEIL2,SGSH,NEU1,NT5M,PGLYRP1,FBXO2,NEU2,DCN
GO:0009409	response to cold	GO_RESPONSE_TO_COLD	-0.170976087566039	-0.654907209120637	0.967116168630438	0.993474455120872	41	PCSK1N,GK,LPL,EIF2AK3,PPARG,CDH8,EIF2AK4,DNAJC3,HSP90AA1,ATP2B1,ZNF516,TRPA1
GO:1903727	positive regulation of phospholipid metabolic process	GO_POSITIVE_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS	0.174338907324952	0.642370921326566	0.967282121693886	0.993474455120872	40	PDGFB,ATG14,FLT1,IRS1,ERBB4,TEK,FABP3,ZP3
GO:0045740	positive regulation of dna replication	GO_POSITIVE_REGULATION_OF_DNA_REPLICATION	0.163671825169704	0.701376657862117	0.967501266751699	0.993474455120872	85	HMBOX1,PDGFB,PARM1,GLI2,OBFC1,MAP3K4,UCN,E2F8,MAPKAPK5,TCP1,ACD,CSF2,MAPK1,CDK1,CCT3,ATRX,TGFB3,CCT7,WRAP53,CCT4,PRKCQ,PKIB,EREG,MAP2K7,E2F7,NEK7,SHC1,ATM,MAPK3,CCT8,INSR,PDGFRA
GO:0046605	regulation of centrosome cycle	GO_REGULATION_OF_CENTROSOME_CYCLE	0.175449349129295	0.622851736223037	0.968095168800931	0.993599494512181	34	NPM1,ROCK2,CHORDC1,CEP85,PLK4
GO:0050810	regulation of steroid biosynthetic process	GO_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS	-0.167383549173004	-0.661280788070598	0.968340168551985	0.993599494512181	47	BMP2,TSPO,AKR1C3,STAR,SCAP,BMP5,LEP,ABCG1,CYP7A1,FGFR4,SIRT1,ATP1A1,SNAI2,APOE,SEC14L2
GO:0046649	lymphocyte activation	GO_LYMPHOCYTE_ACTIVATION	0.155507418712805	0.800440338110125	0.968907309481841	0.993599494512181	314	RC3H2,PIK3R1,RSAD2,ATP7A,UNC13D,STAT5B,HDAC9,CRTAM,ITFG2,LFNG,TSC1,MFNG,SPN,KLRF2,VAMP2,HSPD1,FNIP1,HELLS,HDAC4,CHD7,CD8A,NCSTN,CD40,ERCC1,DNAJA3,LAX1,LAT2,SHH,DLL4,EP300,ADA,CD3G,IRF1,IL18R1,AICDA,IL4,PATZ1,ULBP1,MICA,CD8B,SLA2,ITGB2,TNFSF8,EXOSC3,PSMB10,P2RX7,ITGAL,SPI1,IL11,RHOH,MALT1,IL2,CD80,HMGB1,SMAD3,BTK,IL21R,JMJD6,PRKDC,LILRB1,BCL6,RNF168,ITPKB,IFNA21,TNFSF4,FOXN1,SATB1,TLR4,AXL,IMPDH1,HDAC5,BAK1,LYL1,MEF2C,SRF
GO:0071453	cellular response to oxygen levels	GO_CELLULAR_RESPONSE_TO_OXYGEN_LEVELS	0.159404131344002	0.736552151380035	0.968957233725809	0.993599494512181	134	BAD,PPARD,EPAS1,ADRB2,VLDLR,CREBBP,TSC1,CPEB2,HIPK2,SUV39H1,PINK1,NKX3-1,PTEN,SIRT4,HP1BP3,STC2,SLC8A1,EGLN1,EP300,MTOR,FOXO1,VEGFA,SLC2A4,PLAU,FAM162A,CUL2,ENDOG,PRKCE,NDNF,TWIST1,TRPC6,AIFM1,MT3,PDK3,MYOCD,MDM4,BNIP3,SIRT2
GO:0002244	hematopoietic progenitor cell differentiation	GO_HEMATOPOIETIC_PROGENITOR_CELL_DIFFERENTIATION	0.162004443784383	0.706885787997539	0.969957378980561	0.993599494512181	94	ADAR,STON2,WDR7,DHTKD1,REST,MLF1,SHH,EP300,SSBP3,TET2,SP7,HOXB3,FLI1,SPI1,IL11,HYAL2,MEOX1,C6orf25,SERPINB12,PRKDC,COL24A1,MED1,ZNF784,EML1,SRF,NARFL,ACE,SIN3A,ABI1,ZBTB24,DACT2,JAM3,PAPD4,CDK6,VPS33B,TAL1,HOXB4,TGFB1,SOX4
GO:1904872	regulation of telomerase rna localization to cajal body	GO_REGULATION_OF_TELOMERASE_RNA_LOCALIZATION_TO_CAJAL_BODY	0.196787205356589	0.565461634252871	0.969962266956635	0.993599494512181	15	TCP1,CCT3,NAF1,CCT7,CCT4,CCT8,DKC1
GO:0050830	defense response to gram positive bacterium	GO_DEFENSE_RESPONSE_TO_GRAM_POSITIVE_BACTERIUM	-0.162601273292959	-0.687042196164375	0.970034424600883	0.993599494512181	65	PLA2G2A,HIST1H2BE,HIST1H2BK,RIPK2,C5AR1,MBL2,PGLYRP1,NOD1,HMGB2,DROSHA,TLR2,HIST1H2BF,CARD9,FAU,PGLYRP2,CAMP
GO:0030098	lymphocyte differentiation	GO_LYMPHOCYTE_DIFFERENTIATION	0.15680641192611	0.763482913496922	0.97025028065773	0.993599494512181	196	RC3H2,PIK3R1,RSAD2,ATP7A,STAT5B,HDAC9,ITFG2,LFNG,TSC1,MFNG,SPN,FNIP1,HDAC4,CHD7,CD8A,DNAJA3,SHH,DLL4,EP300,ADA,IRF1,IL18R1,AICDA,IL4,PATZ1,TNFSF8,SPI1,IL11,RHOH,MALT1,IL2,HMGB1,JMJD6,PRKDC,BCL6,ITPKB,IFNA21,FOXN1,SATB1,AXL,HDAC5,BAK1,LYL1,SRF
GO:0090208	positive regulation of triglyceride metabolic process	GO_POSITIVE_REGULATION_OF_TRIGLYCERIDE_METABOLIC_PROCESS	0.19134853164313	0.568441315196067	0.97027972027972	0.993599494512181	17	APOC3,LDLR,APOA5,CTDNEP1,PNPLA2,GPLD1
GO:0010824	regulation of centrosome duplication	GO_REGULATION_OF_CENTROSOME_DUPLICATION	0.177838743227171	0.602594236094429	0.971253543019109	0.994245769476947	28	NPM1,ROCK2,CHORDC1,PLK4
GO:0043496	regulation of protein homodimerization activity	GO_REGULATION_OF_PROTEIN_HOMODIMERIZATION_ACTIVITY	-0.179619923100803	-0.588875148337678	0.971810641045282	0.994245769476947	22	TRAF4,BAX,BCL2,NRG1,ISL1
GO:0051412	response to corticosterone	GO_RESPONSE_TO_CORTICOSTERONE	-0.175737976044975	-0.602345217134219	0.971977212238524	0.994245769476947	26	CDKN1A,STAR,SLC18A2,PTGS1,BAX,JUNB,ATP2B1,NTS,FOS,FOSB,TRH
GO:0042994	cytoplasmic sequestering of transcription factor	GO_CYTOPLASMIC_SEQUESTERING_OF_TRANSCRIPTION_FACTOR	-0.183063437912863	-0.576568190103613	0.972262044398106	0.994245769476947	19	KEAP1,PSMD10,PKD2,IL10,TONSL,SRI
GO:0009314	response to radiation	GO_RESPONSE_TO_RADIATION	0.154030500656164	0.807853928544372	0.972544434050514	0.994245769476947	376	BRSK1,NLGN3,UBE4B,PIK3R1,CACNA2D4,RHO,FBXW7,NR2F6,DRD4,APP,ZAK,NDRG4,UNC119,DMC1,CREBBP,CCND1,HRH2,N4BP1,CYP17A1,ATP1A2,YAP1,DRD2,OPRK1,SLC24A1,TYR,ABCA4,RPE65,EYA1,HMGCR,RP1,USP2,REV1,PTPRK,MAP3K4,ZRANB3,NFATC4,ERCC1,TRPM1,SMC1A,TLK2,TRIM13,NPS,SLC4A10,ALAD,EP300,POLG,ERCC4,INTS3,GNAT2,MTOR,CCR2,CREB1,OPN5,RGS14,TOPBP1,HMGCS1,RAD51AP1,TRIM32,GJA10,CYBA,USP28,GTF2H5,HUS1,GADD45A,CABP4,KRT13,PBK,TANC1,HYAL1,IMPACT,PPP1CB,IVL,ELK1,HYAL2,ASNS,RHBDD1,ATP1A3,PRKDC,RNF168,APOBEC1,TSPYL5,MAPK8,MTA1,UBE2B
GO:0010592	positive regulation of lamellipodium assembly	GO_POSITIVE_REGULATION_OF_LAMELLIPODIUM_ASSEMBLY	0.19432707223179	0.558392521732534	0.972973475343408	0.994245769476947	15	HDAC4,MTOR,DNM2,RAC2,BRK1,TWF2,WNT1
GO:0070584	mitochondrion morphogenesis	GO_MITOCHONDRION_MORPHOGENESIS	-0.185709293345706	-0.567955516914654	0.973071765367479	0.994245769476947	17	MTM1,BAX,MFF
GO:0032727	positive regulation of interferon alpha production	GO_POSITIVE_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION	0.192079347881652	0.561243374025995	0.973273859306756	0.994245769476947	16	HSPD1,DDX58,HMGB1,TLR4,IFIH1,MAVS,TBK1
GO:0033138	positive regulation of peptidyl serine phosphorylation	GO_POSITIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION	-0.158911277593754	-0.705885286049141	0.973710016343684	0.994389537321857	84	PRKD1,WNT5A,SFRP2,ANGPT1,SNCA,RIPK2,IFNA14,IFNE,RAPGEF3,OPRD1,BCAR3,IFNA16,DOCK7,MIF,CDC42,AXIN1,RET,BCL2,PDCD10
GO:0006302	double strand break repair	GO_DOUBLE_STRAND_BREAK_REPAIR	0.15726001286644	0.730405331466789	0.97447031392559	0.994864142151513	139	HERC2,ZSWIM7,ZFYVE26,DMC1,UBE2N,EYA1,EXD2,RAD21L1,HIST1H4F,FBXO18,ERCC1,LIG3,ERCC4,SETX,MMS22L,RECQL5,RAD51AP1,VCP,PRPF19,HUS1,SFPQ,SUMO1,PRKDC,RNF168,PIAS4,MRE11A,MTA1,UVRAG,FAN1,CCDC155,BABAM1,HIST1H4A,BRCA2,PAXIP1,WRN,PAPD7,NSMCE2,PALB2,MLH1,DCLRE1A,HIST3H3
GO:1903307	positive regulation of regulated secretory pathway	GO_POSITIVE_REGULATION_OF_REGULATED_SECRETORY_PATHWAY	0.164874381258463	0.635024126122893	0.976557303370787	0.995789868790655	49	UNC13D,SYT9,STX1A,ARF1,SYT7,STX4,IL4,ADORA2B,PTAFR,ZP3,RAB3A,DOC2B,TMEM27,AP1G1,GLRA1,FAM170B,CDK5R2,GAB2,POMZP3
GO:1901798	positive regulation of signal transduction by p53 class mediator	GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	-0.188246854506339	-0.554569064511625	0.976711468952232	0.995789868790655	15	HEXIM1,UBB,CHD5,SPRED2,PMAIP1
GO:0032653	regulation of interleukin 10 production	GO_REGULATION_OF_INTERLEUKIN_10_PRODUCTION	0.166132654768724	0.628376427136809	0.977118598334263	0.995789868790655	45	TRIB2,XCL1,HSPD1,IDO1,PRG2,PRKCZ,IL4,HMGB1,LILRB1,TNFSF4,TLR4
GO:0006633	fatty acid biosynthetic process	GO_FATTY_ACID_BIOSYNTHETIC_PROCESS	0.158591522040342	0.69793454063176	0.97733397830143	0.995789868790655	99	HSD17B8,NDUFAB1,FADS1,LIPT2,PRKAB2,THNSL2,PLA2G5,QKI,LIAS,PRKAA2,MGLL,MSMO1,ELOVL6,PTGDS
GO:0048708	astrocyte differentiation	GO_ASTROCYTE_DIFFERENTIATION	0.168202961710635	0.609241382705138	0.977352137154444	0.995789868790655	37	EIF2B5,LAMB2,SHH,MAPK1,PAX6,SOX9,NKX2-2,TLR4,PLP1,MT3,SMO,NF1,MAPK3,CDK6,TAL1
GO:0072523	purine containing compound catabolic process	GO_PURINE_CONTAINING_COMPOUND_CATABOLIC_PROCESS	-0.162386692083085	-0.641539746548754	0.977376177385191	0.995789868790655	47	AOX1,MPG,NUDT18,CAT,PDE11A
GO:0090025	regulation of monocyte chemotaxis	GO_REGULATION_OF_MONOCYTE_CHEMOTAXIS	0.182111036876829	0.557281135959888	0.977447928248462	0.995789868790655	19	CCR2,S100A7,HMGB1,PLA2G7,CXCL12,CCL5,CCR1,CXCL10,TNFSF18
GO:0031623	receptor internalization	GO_RECEPTOR_INTERNALIZATION	-0.162177118127363	-0.634406057128709	0.978203598207651	0.996250803435512	45	EZR,RAB31,SNCA,HTR1B,GTF2H2
GO:0048013	ephrin receptor signaling pathway	GO_EPHRIN_RECEPTOR_SIGNALING_PATHWAY	-0.157019424848178	-0.695536838635495	0.978604498900996	0.996250803435512	83	EPHB6,EFNB3,SS18,EFNA5,ARPC5,ACTG1,ACTR3,GIT1,PAK3,EPHA2,EPHA6,RHOA,CDC42,APH1B,RAC1,HRAS,ITSN1
GO:0006897	endocytosis	GO_ENDOCYTOSIS	0.152116357184721	0.811770700119721	0.978788296779929	0.996250803435512	452	EHD1,EHD4,LRP5,NLGN3,SH3GL1,LRSAM1,TINAGL1,PIK3R1,CYFIP2,MAPKAPK2,UNC13D,DNER,LMBR1L,CUBN,SNX11,LRP6,APP,ADRB2,UNC119,LRRK2,VLDLR,FCN1,LDLR,STON2,TSC2,DRD2,LRP3,PACSIN2,PEAR1,MARCH2,MAPKAPK3,INPPL1,SYT7,PI4KB,CAV3,LBP,C9orf72,SGIP1,LRPAP1,GRIA1,TGFBR2,PIKFYVE,LIMK1,TUB,ITSN2,TRIP10,DNM3,SHH,MYO10,CDC42SE1,WASL,SNX30,AAK1,CD3G,GULP1,FNBP1L,IGF2R,RAMP3,DBNL,OPHN1,HBA1,EPS15L1,SYT12,MAPK1,STEAP2,EPN2,ITGB2,FCGR3A,PDLIM7,AP2M1,P2RX7,CD93,GRK4,NPC1,CETP,CLTCL1,PLCG1,SORT1,ELMO2,TMEM175,CSNK1A1,ELMO1,HMGB1,PIP5K1C,CD36,RIN3,APOL1,JMJD6,ATP9B,ENPP3,LILRB1,HIP1R,PRKCE,PTX3,PGBD1,CALCR,CD247,TREM2,LRP1B,EIF2AK1,NECAP1,INPP5F,AXL,DPYSL2,GATA2
NA	regulation of glucose transport	GO_REGULATION_OF_GLUCOSE_TRANSPORT	0.157294217328404	0.683786308783632	0.980556760038158	0.997562294579961	92	PIK3R1,AKT2,POM121,GRB10,ESR1,NUP85,RAE1,PIK3R3,ADIPOR2,IRS1,GCK,PRKCZ,NUP188,TNF,TRIB3,CLTCL1,PTH,TPR,AAAS,MARCKS,POM121C
NA	regulation of interleukin 6 biosynthetic process	GO_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS	0.183634675224546	0.53656858922019	0.981172753461574	0.997562294579961	16	GHSR,INPP5D,PTAFR,FOXJ1,EREG
GO:0002360	t cell lineage commitment	GO_T_CELL_LINEAGE_COMMITMENT	0.186070720696053	0.534668164125521	0.981207829141806	0.997562294579961	15	SHH,IL4,PRKDC,FOXN1,FOXP3
GO:0000726	non recombinational repair	GO_NON_RECOMBINATIONAL_REPAIR	0.160735601979995	0.636641788971439	0.981262257086825	0.997562294579961	56	HERC2,UBE2N,HIST1H4F,LIG3,PRPF19,SUMO1,PRKDC,RNF168,PIAS4,MRE11A,UVRAG,BABAM1,HIST1H4A,PAXIP1,NSMCE2,MLH1,DCLRE1A,HIST3H3,ATM,SETMAR,TP53BP1,RNF138,SLX4,C9orf142,DCLRE1C,BRE
GO:0006260	dna replication	GO_DNA_REPLICATION	0.153630390772762	0.742978246977452	0.98204326167188	0.997795560840427	186	RPA4,ORC2,NASP,PDGFB,MCM4,KAT7,NFIB,MCM7,IGHMBP2,ORC6,HMGA1,POLA2,REV1,FBXO18,ZRANB3,DNAJA3,LIG3,REV3L,POLG,POLD2,GINS3,CCNE2,MMS22L,RECQL5,RFC3,TOPBP1,CDK1,CCDC88A,HUS1,ORC3,WRNIP1,CDC25C,ATRX,CLSPN,GINS1,POLK,MRE11A,EGF,TIPIN,KIN,SSBP1,PRIM1,CDC34,ING5,BRCA2,TOP2B,NFIA,WRN,SIN3A,RAD1,EXO1,MCM3AP,RMI1,TOP3A,PARP2,RBBP6,UPF1,ATM,PARP3,RPA1,SETMAR
GO:0002286	t cell activation involved in immune response	GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	-0.156830831044398	-0.647850296805921	0.982084579044663	0.997795560840427	58	GATA3,IFNA14,IRF4,IFNE,EIF2AK4,APBB1IP,CLEC4E,IFNA16,SEMA4A,PTGER4,RPS6,PSEN1
GO:0050832	defense response to fungus	GO_DEFENSE_RESPONSE_TO_FUNGUS	0.164547928981226	0.587922445382345	0.982730412652245	0.997954413868265	35	VIP,APP,CLEC6A,DCD,HAMP,NPY,IL17A,GNLY,ADM
GO:0070661	leukocyte proliferation	GO_LEUKOCYTE_PROLIFERATION	-0.153378563523307	-0.678005257755461	0.983230959665553	0.997954413868265	82	TNFSF11,TNFSF14,ELF4,IMPDH2,RAG2,RIPK2,CSF1,IFNA14,IFNE,IFNA16,BAX,FLT3,RPS6,ABL1,IL10,BCL2
GO:0022409	positive regulation of cell cell adhesion	GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION	-0.149394054924922	-0.774096434660105	0.983288787399123	0.997954413868265	229	CD55,DPP4,TNFSF11,CCL19,EFNB3,RARA,IL18,WNT5A,TNFSF14,GATA3,ALOX15,HLA-DRB5,FOXA1,ANXA1,MAP3K8,XBP1,IL6ST,PYCARD,CCL21,NR4A3,RIPK2,IL36B,PIEZO1,LEP,TNFSF9,LILRB2,RAG1,ZBTB1,PAK3,NLRP3,SART1,BTLA,GRAP2,PDPK1,NKAP,IL2RA,NODAL,VTCN1,CDC42,HLA-DRB1,GPAM
GO:0018212	peptidyl tyrosine modification	GO_PEPTIDYL_TYROSINE_MODIFICATION	-0.149761195237289	-0.750830025525985	0.983722041915113	0.997954413868265	179	TYRO3,KDR,FGF22,EFEMP1,NRG4,MAP2K4,MET,FGF7,FGFR2,MAP2K2,ALK,FGF17,SCYL1,FGF18,MST1R,TWF1,RIPK2,MELK,EGFR,FGF4,LEP,FGF9,LTK,IL5,EPHA2,EPHA6,FLT3,F2R,TXK,HSP90AA1,SGK223,FGFR4,MATK,ABL1,RET,SRMS,NRG1,FGF2,TRIM27,DDR1,MAP2K5,ZAP70,FGF16,IL3RA,PKDCC
GO:0002768	immune response regulating cell surface receptor signaling pathway	GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY	0.151355507676342	0.772211354910508	0.984266824424796	0.997954413868265	289	CTLA4,PRKACA,PIK3R1,CYFIP2,RBCK1,PSMD11,CALM3,CREBBP,PSMD2,UBE2N,PSMC6,FCN1,RNF31,BTRC,PTEN,INPP5D,CLEC6A,PSMC5,PSMB7,CD40,LIMK1,PSME4,ICAM3,ICAM2,LAX1,LAT2,CALM1,RAF1,MYO10,EP300,WASL,CD3G,PPP3R1,CR1,IKBKB,PSMA8,SLA2,MAPK1,FCGR3A,PSMD8,PSMB10,MALT1,PLCG1,PSMD3,PSMB1,ELMO2,CD38,NFKB1,ELMO1,PAG1,BTK,PSMA5,PSMB9,LILRB1,PRKCE,MAPK8,CD247,NFKBIA,TEC,PRKCQ,MEF2C,PSMD6,PRKACB,PSMB3,PIK3R2,PIK3CB,HLA-DQA1,PSMB6,PSMD1,NFATC1,MAP2K7,GRB2,CD4,NCKIPSD,GPLD1,RPS6KA5,HSP90AB1,ABI1,SPPL3
GO:0009268	response to ph	GO_RESPONSE_TO_PH	0.161846035072639	0.586216206838434	0.98437641435994	0.997954413868265	37	GJA1,GJA3,INSRR,CA2,PKD2L1,HYAL1,IMPACT,SLC38A3
GO:0070168	negative regulation of biomineral tissue development	GO_NEGATIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT	-0.176231139040833	-0.538968437535703	0.984621706968897	0.997954413868265	17	CCL3,HIF1A
GO:0048265	response to pain	GO_RESPONSE_TO_PAIN	0.165259920155594	0.559971767321689	0.985261040504709	0.997954413868265	28	SLC6A2,OSM,UCN,CACNA1B,NMUR2
GO:0000381	regulation of alternative mrna splicing via spliceosome	GO_REGULATION_OF_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME	0.164003779721762	0.574169140640661	0.985485603977345	0.997954413868265	32	RBM10,THRAP3,RNPS1,RBFOX1,RBM5,RBM8A,DYRK1A,SRSF12,MBNL2
GO:0038094	fc gamma receptor signaling pathway	GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY	-0.152825736493243	-0.667771939651503	0.985491408774908	0.997954413868265	77	FCGR2A,ARPC5,ACTG1,ACTR3,BAIAP2,IGHG4,IGHG2,IGHG1,CLEC4E,IGKC,WIPF2,HSP90AA1,IGLC1,CDC42,ABL1,PLD2,RAC1
GO:0031294	lymphocyte costimulation	GO_LYMPHOCYTE_COSTIMULATION	-0.152735315784724	-0.657177601791035	0.985502219755827	0.997954413868265	71	DPP4,CCL19,EFNB3,TNFSF14,HLA-DRB5,MAP3K8,CCL21,PAK3,BTLA,GRAP2,PDPK1,CDC42,HLA-DRB1
GO:0001678	cellular glucose homeostasis	GO_CELLULAR_GLUCOSE_HOMEOSTASIS	0.154120574795362	0.638204827094572	0.986510791366906	0.998344038234395	70	PRKACA,PIK3R1,APOC3,PTPRN,GCK,RAF1,GRIK5,EP300,POLG,FOXO1,CYBA,HK3,PLAU,ENDOG,TH,NOX4,SRF,PIK3R2,PDK3,SIN3A,PPARGC1A
GO:0009988	cell cell recognition	GO_CELL_CELL_RECOGNITION	-0.153383954294948	-0.631284614021464	0.986617506486413	0.998344038234395	57	ZAN,CCL19,ZP1,CCL21,ADAM30,ATP8B3,IZUMO1,DLG1,CCT5,CLGN,CATSPER1,ADAM2,CD6,B4GALT1,ZP4,SPA17,CCT2,CCR7,EPHB1,DOCK2,PCSK4,CATSPER3
GO:0046916	cellular transition metal ion homeostasis	GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS	0.154464529916478	0.644564477801502	0.986776772194246	0.998344038234395	73	HFE2,ATP7A,SCO1,APP,FTMT,ARF1,SLC39A14,HAMP,FLVCR1,SOD1,SLC30A1,FXN,HEPH,ABCG2,HMOX2,MT3,IREB2,SLC31A2,TTC7A,TMPRSS6,PRNP,ABCB7,TFR2
GO:0033280	response to vitamin d	GO_RESPONSE_TO_VITAMIN_D	-0.158345896138707	-0.562691826231402	0.988357422696385	0.999489526201017	30	AQP3,ALPL,PIM1
GO:0070306	lens fiber cell differentiation	GO_LENS_FIBER_CELL_DIFFERENTIATION	0.162573920073608	0.535242557907777	0.988585270962177	0.999489526201017	25	FZR1,CRYGB,TMOD1,SMAD3,PROX1,NTRK3
NA	stat cascade	GO_STAT_CASCADE	0.156640814794285	0.597935187392022	0.988799798648066	0.999489526201017	47	STAT5B,STAMBP,OSM,JAK2,GH1,CCR2,MAPK1
GO:0038083	peptidyl tyrosine autophosphorylation	GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION	-0.153632030802192	-0.581728685302848	0.989815104982764	0.999689707412342	39	KDR,TXK,MATK,ABL1,SRMS,DDR1,ZAP70,PTK2B,FES,FRK,FER,PTK6,LCK,YES1
GO:0045089	positive regulation of innate immune response	GO_POSITIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE	0.148337489788775	0.738686416723238	0.990373983739837	0.999689707412342	234	PRKACA,MAPKAPK2,STAT5B,CRTAM,PSMD11,CREBBP,PSMD2,UBE2N,PSMC6,FCN1,HSPD1,MAPKAPK3,BTRC,DDX58,LBP,PIK3C3,POLR3F,CLEC6A,PSMC5,PSMB7,REG3G,PSME4,ICAM3,ICAM2,RAF1,EP300,GBP5,IKBKB,TMEM173,PSMA8,ITGB2,PSMD8,PSMB10,SH2D1B,MALT1,PSMD3,PSMB1,NFKB1,HMGB1,CD36,BTK,SH2D1A,PSMA5,PSMB9,PRKCE,NFKBIA,TLR4,MED1,IL21,PSMD6,PRKACB,PSMB3,PSMB6,TICAM1,EREG,PSMD1,AP1G1,UBE2K
GO:0045088	regulation of innate immune response	GO_REGULATION_OF_INNATE_IMMUNE_RESPONSE	0.147980675844081	0.765142716561162	0.990713935424675	0.999689707412342	327	ADAR,PRKACA,RSAD2,MAPKAPK2,STAT5B,C1QBP,CRTAM,PSMD11,CREBBP,PSMD2,UBE2N,PSMC6,FCN1,DRD2,HSPD1,MAPKAPK3,BTRC,JAK2,DDX58,LBP,PELI1,PIK3C3,POLR3F,CLEC6A,PSMC5,PSMB7,REG3G,PSME4,ICAM3,HLA-B,DNAJA3,ICAM2,RAF1,EP300,TYK2,IRF1,CR1,GBP5,IKBKB,ANKRD17,TMEM173,MICA,PSMA8,ITGB2,PSMD8,PSMB10,CYBA,SH2D1B,MALT1,PSMD3,PSMB1,NFKB1,HMGB1,CD36,BTK,SH2D1A,PSMA5,SUMO1,OTUD7A,PSMB9,LILRB1,PRKCE,USP18,IFNA21,NFKBIA,TLR4,MED1,FLOT1,IL21,PSMD6,PRKACB,PIK3R6,IFNA4,PSMB3,DDX60,PSMB6,TICAM1,EREG,PSMD1,DUSP10,AP1G1,UBE2K
GO:0002218	activation of innate immune response	GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE	0.148422623680755	0.722041096384955	0.990741659226929	0.999689707412342	195	PRKACA,MAPKAPK2,PSMD11,CREBBP,PSMD2,UBE2N,PSMC6,FCN1,HSPD1,MAPKAPK3,BTRC,DDX58,LBP,PIK3C3,CLEC6A,PSMC5,PSMB7,REG3G,PSME4,ICAM3,ICAM2,RAF1,EP300,IKBKB,TMEM173,PSMA8,ITGB2,PSMD8,PSMB10,MALT1,PSMD3,PSMB1,NFKB1,HMGB1,CD36,BTK,PSMA5,PSMB9,PRKCE,NFKBIA,TLR4
GO:0032816	positive regulation of natural killer cell activation	GO_POSITIVE_REGULATION_OF_NATURAL_KILLER_CELL_ACTIVATION	-0.166343984394039	-0.508730510682028	0.9915430202881	0.999689707412342	17	IL18,ZBTB1,BLOC1S3,GAS6,IL23R
GO:0000097	sulfur amino acid biosynthetic process	GO_SULFUR_AMINO_ACID_BIOSYNTHETIC_PROCESS	0.165997362302732	0.493130300693534	0.991686504984377	0.999689707412342	17	MTR,EIF2B4,CTH,BHMT,MTRR,ENOPH1,BHMT2,MTHFD2L
GO:0010212	response to ionizing radiation	GO_RESPONSE_TO_IONIZING_RADIATION	-0.145455983423073	-0.696036367304359	0.991894333357748	0.999689707412342	131	KDM1A,SFRP2,GATA3,SWI5,ANXA1,MEN1,FIGNL1,TP73,KDM4D,CDKN1A,STAR,HIF1A,CASP3,KRT14,DCUN1D3,BRCC3,CHEK2,XRCC2,BAX,RNF8,MYC,RAD51B,IFI16,SOCS3,SIRT1,XRCC5,BCL2,THBD,XRCC4
GO:1902017	regulation of cilium assembly	GO_REGULATION_OF_CILIUM_ASSEMBLY	-0.149514587406727	-0.584872644027601	0.992119069599874	0.999689707412342	45	HAP1,TBC1D2B,TBC1D2,TBC1D9B,IFT20,ADAMTS16,IFT88,TBC1D10A,IFT140,SEPT9,SEPT7,TBC1D5,SGSM3,TBC1D10C,MNS1,CCDC151
GO:0038093	fc receptor signaling pathway	GO_FC_RECEPTOR_SIGNALING_PATHWAY	0.146657477911078	0.708438212763845	0.992827325735489	0.999689707412342	184	PIK3R1,CYFIP2,PSMD11,CALM3,PSMD2,UBE2N,PSMC6,BTRC,PSMC5,PSMB7,LIMK1,PSME4,LAT2,CALM1,MYO10,WASL,CD3G,PPP3R1,IKBKB,PSMA8,MAPK1,FCGR3A,PSMD8,PSMB10,MALT1,PLCG1,PSMD3,PSMB1,ELMO2,NFKB1,ELMO1,BTK,PSMA5,PSMB9,PRKCE,MAPK8,CD247,NFKBIA,TEC,PRKCQ,PSMD6,PSMB3,PIK3R2,PIK3CB,PSMB6,PSMD1,NFATC1,MAP2K7,GRB2,NCKIPSD,HSP90AB1,ABI1,PPP3CB,PSME2,PTK2,SHC1,UBE2D1
GO:0006790	sulfur compound metabolic process	GO_SULFUR_COMPOUND_METABOLIC_PROCESS	-0.144500763437641	-0.781318959257023	0.993150126396477	0.999689707412342	327	CHAC2,SULF1,PAX8,LIPC,GSTZ1,OCLN,B3GALT6,FMOD,MGST1,ANGPT1,PEMT,HS6ST3,GSTM3,EEF1G,TXNDC2,CHAC1,PC,EXTL2,ACSBG2,SPOCK2,PAPSS2,PDZD11,THEM5,SULF2,HPSE,B4GALT2,DGAT2,CLIC3,IDUA,CPS1,CHST8,NDST3,BTD,GLYAT,ACOT4,SLC19A3,GAL3ST4,HLCS,KEAP1,B4GALT5,EXT1,GGT1,HS3ST5,AGXT,GGCT,FASN,MVK
GO:0036344	platelet morphogenesis	GO_PLATELET_MORPHOGENESIS	0.159636406084309	0.488506129276434	0.993495663775851	0.999689707412342	19	NBEAL2,EP300,C6orf25,MEF2C,SRF,CASP9
GO:0021542	dentate gyrus development	GO_DENTATE_GYRUS_DEVELOPMENT	0.166436525512428	0.478249942851154	0.99375453075336	0.999689707412342	15	PTEN,PROX1,SMO,CDK6,NEUROD6
GO:0006312	mitotic recombination	GO_MITOTIC_RECOMBINATION	0.14946116910811	0.537579988582299	0.993777777777778	0.999689707412342	36	DMC1,POLA2,ERCC1,POLD2,RFC3,PRIM1,BRCA2,TOP2B,WRN,NSMCE2
GO:0042102	positive regulation of t cell proliferation	GO_POSITIVE_REGULATION_OF_T_CELL_PROLIFERATION	-0.142503034262542	-0.642867345342963	0.994356152738092	0.999689707412342	92	CD55,CCL19,IL18,ANXA1,IL6ST,PYCARD,RIPK2,LEP,TNFSF9,LILRB2
GO:0051054	positive regulation of dna metabolic process	GO_POSITIVE_REGULATION_OF_DNA_METABOLIC_PROCESS	0.144952018931593	0.693411695595597	0.994677489105485	0.999689707412342	171	HMBOX1,PDGFB,UNG,PARM1,GLI2,UBE2N,EYA1,GSK3B,OBFC1,MAP3K4,UCN,DDX39B,CD40,ERCC1,E2F8,MAPKAPK5,TCP1,ACD,IL4,CSF2,RFC3,MAPK1,CDK1,EXOSC3,PRDM9,CCT3,ATRX,IL2,HMGB1,ENDOG,RNF168,MRE11A,TNFSF4,UBE2B,TGFB3,CCT7,WRAP53,CCT4,PRKCQ,BABAM1,NOX4,PKIB,PAXIP1,EREG,MAP2K7,NPAS2,PPARGC1A,E2F7,NEK7,EYA3,SHC1,TRIM28,CBX8,ATM,PARP3,MAPK3,SETMAR,CCT8,INSR,PDGFRA,TMEM161A
GO:0010171	body morphogenesis	GO_BODY_MORPHOGENESIS	-0.144353830877653	-0.549695975497	0.995005599104143	0.999689707412342	40	CDON,MAB21L2,SGPL1,PAX9,ASPH,STRA6,CSRNP1,WNT3,NOG
GO:0006471	protein adp ribosylation	GO_PROTEIN_ADP_RIBOSYLATION	-0.15176633208626	-0.484978814931358	0.995409251120491	0.999689707412342	20	ART5,SIRT6,PARP4,SIRT1,ARF4
GO:0032735	positive regulation of interleukin 12 production	GO_POSITIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION	0.146680479347444	0.517106591800043	0.995736151603498	0.999689707412342	33	HSPD1,CD40,IDO1,IRF1,HMGB1,CD36,TNFSF4,TLR4,IRF8
GO:0032647	regulation of interferon alpha production	GO_REGULATION_OF_INTERFERON_ALPHA_PRODUCTION	-0.151876891748481	-0.478344477697756	0.995916416873018	0.999689707412342	19	RIPK2,IRF7,TLR9,IL10,TLR3
GO:0051052	regulation of dna metabolic process	GO_REGULATION_OF_DNA_METABOLIC_PROCESS	0.143808229634677	0.739522645611926	0.995976655057806	0.999689707412342	311	TFIP11,CUL4A,HMBOX1,TRIP12,FBXW7,PDGFB,NPM1,UNG,SMG6,PARM1,GLI2,UBE2N,ZNF91,MCRS1,EYA1,FIGNL2,GJA1,GSK3B,OBFC1,MAP3K4,UCN,FBXO18,DDX39B,ZRANB3,DACH1,CD40,UBR5,ERCC1,E2F8,GTPBP4,SMC1A,LIG3,MAPKAPK5,TCP1,ERCC4,ACD,TERF2IP,ANKRD17,IL4,APOBEC3D,CSF2,MPHOSPH8,RFC3,MAPK1,CDK1,EXOSC3,RAD51AP1,CCDC88A,HUS1,WRNIP1,PRDM9,CCT3,SPI1,ATRX,IL2,APOBEC3H,HMGB1,ENDOG,BCL6,RNF168,MRE11A,TNFSF4,UBE2B,TGFB3,CCT7,TIPIN,WRAP53,CCT4,PRKCQ,BABAM1,NOX4,TWIST1,PKIB,BRCA2,AIFM1,PAXIP1,EREG,MAP2K7,FIGN,OGG1,NPAS2,MLH1,PPARGC1A,HNRNPU,PPP4R2,E2F7,FOXP3,NEK7,CDKN2A,EYA3,RBBP6,SHC1,PPP2R1A,TRIM28,CBX8,ATM,PARP3,MAPK3,SETMAR,CCT8,INSR,PDGFRA,TMEM161A
NA	regulation of interleukin 2 biosynthetic process	GO_REGULATION_OF_INTERLEUKIN_2_BIOSYNTHETIC_PROCESS	-0.151738661248161	-0.471217412199362	0.996619352042475	0.999689707412342	18	IRF4,IL17F,CARD9,CD276,IL1A,CD3E,GLMN
GO:0044272	sulfur compound biosynthetic process	GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS	0.141306254189614	0.681679821298471	0.99693607154687	0.999689707412342	182	DLAT,AGK,HS3ST3B1,ACOT6,HAGH,ACOT2,DLD,NDST1,MTR,LIPT2,ACAN,ST3GAL6,PDHA1,LIAS,ACOT11,CHST13,ST3GAL3,ACSF2,ST3GAL2,HS6ST1,ELOVL6,MGST3,PDHX,XYLT1,GGT7,GSS,ACOT8,PDHB,HS6ST2,EIF2B4,ACACB,GCDH,TPK1
GO:0051301	cell division	GO_CELL_DIVISION	-0.141412874272781	-0.783299648058637	0.996985124719133	0.999689707412342	416	KIF2C,CCNF,SEPT10,REEP3,CCNG1,PARD6B,RBBP8,CUL7,KATNB1,CCDC124,KIF20A,FGFR2,KATNA1,NEK2,CEP55,POU3F2,POU3F3,ACTR3,CETN2,ERCC6L,SYCE3,GNAI1,MIS12,BRSK2,MARK4,CENPW,MCMBP,CDCA2,ANLN,ZFYVE19,RAB10,TOP2A,TRIOBP,SPICE1,SPC24,CCNB1,CDC123,KIAA0196,CDK5,RPS3,MIS18BP1,FBXO5,E4F1,FGF13,CCNA2,PARD3B,CDCA8,TEX14,CDK14,FMN2,BRCC3,CHEK2,CDC20,TIMELESS,KIF4A,ZNF365,CHMP5,USP16,AURKB,DOCK7,CABLES1,CDC25A,TPX2,RALA,RNF8,SNX33,AURKC,PPP1CA,RHOA,KNTC1,ZW10,TUBA1A,CCNB3,ANKLE2,GTPBP8,FAM64A,PAPD5,MASTL,ANAPC4,CDC6,SPAST,STMN1,SMC3,RAB11A,CETN3,WNT7A,ITGB3BP,NCAPG2,RHOC,RCC2,TERF1,NDC80,LLGL2,NUDC,RAN,KIF2B,BORA,NEK4,NUF2,SEH1L,SEPT2,RAB35,PARD3,DYNLT1
GO:0071897	dna biosynthetic process	GO_DNA_BIOSYNTHETIC_PROCESS	-0.135961826479392	-0.625649894063271	0.997642688763483	0.999689707412342	103	RBBP8,CTGF,RPA3,POLH,NOP10,UBA52,TYMS,RPA2,KIAA0101,ZBTB1,XRCC2,POLQ,TK2,BARD1,RAD51B,NHP2,UBB,PAPD5,SIRT1,NBN,PCNA,POLE2
GO:1903510	mucopolysaccharide metabolic process	GO_MUCOPOLYSACCHARIDE_METABOLIC_PROCESS	-0.132294189464296	-0.606768124734229	0.998336304218657	0.999689707412342	101	B3GALT6,FMOD,ANGPT1,SPOCK2,HAS1,ITIH6,PIM1,B4GALT2,IDUA,NDST3,B4GALT5,HGF,DCN,CHST3,B4GALT4,B3GAT1,STAB2,FGF2,DSEL,CHST6,VCAN,GUSB,B4GALT1,B3GNT2,LUM,CHPF,B3GNT4
GO:0043171	peptide catabolic process	GO_PEPTIDE_CATABOLIC_PROCESS	0.137857818866766	0.427925147253268	0.998649148778682	0.999689707412342	20	CTSH,ACE2,LNPEP,ACE
GO:0071157	negative regulation of cell cycle arrest	GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_ARREST	0.140792169360346	0.424768796577658	0.998718829492916	0.999689707412342	18	CCND1,RASSF1,PHOX2B,MDM4,SETMAR
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	GO_CHONDROITIN_SULFATE_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS	-0.128559846566401	-0.449160127591567	0.998742193878677	0.999689707412342	28	B3GALT6,DCN,CHST3,B3GAT1,CYTL1,VCAN,CHPF
GO:0060323	head morphogenesis	GO_HEAD_MORPHOGENESIS	0.131161233829652	0.459189007967401	0.998761632459799	0.999689707412342	32	LRP6,RAB3GAP1,SSBP3,FLVCR1,TGFB3,MSX1,DKK1,ANKRD11
GO:0017145	stem cell division	GO_STEM_CELL_DIVISION	-0.130607376604287	-0.452174821603137	0.998810546487808	0.999689707412342	27	FGFR2,RAB10,FGF13,DOCK7
GO:0030206	chondroitin sulfate biosynthetic process	GO_CHONDROITIN_SULFATE_BIOSYNTHETIC_PROCESS	0.133171137522256	0.43394187650737	0.998897180458038	0.999689707412342	24	CHST13,XYLT1,CHST9,CSPG4,CSGALNACT1,CHST11,BCAN,CHST7,CHSY1
GO:0007004	telomere maintenance via telomerase	GO_TELOMERE_MAINTENANCE_VIA_TELOMERASE	-0.136689555749459	-0.418038246195898	0.999264610459835	0.999689707412342	17	NOP10,NHP2,TERF1,RFC1,TERF2,GAR1,PINX1,TNKS1BP1,RAD50,POT1,TERT,DKC1,ATM,WRAP53,MRE11A,TERF2IP,ACD
GO:0010833	telomere maintenance via telomere lengthening	GO_TELOMERE_MAINTENANCE_VIA_TELOMERE_LENGTHENING	0.128026819652011	0.421503045508861	0.999376043750344	0.999689707412342	25	OBFC1,ACD,TERF2IP,MRE11A,WRAP53,UPF1,ATM,DKC1,TERT,RAD51,ZSCAN4
GO:0019370	leukotriene biosynthetic process	GO_LEUKOTRIENE_BIOSYNTHETIC_PROCESS	0.13006032553022	0.397999853264334	0.999555259061597	0.999689707412342	19	PLA2G5,GGT7,MGST2,GGTA1P,LTA4H,RNPEP
GO:0045058	t cell selection	GO_T_CELL_SELECTION	-0.117875050247069	-0.435225792261837	0.999666607396871	0.999689707412342	35	GATA3,IRF4,FAS,BCL2,ZAP70,AIRE,CD3E,CCR7,DOCK2,GLI3
GO:0000722	telomere maintenance via recombination	GO_TELOMERE_MAINTENANCE_VIA_RECOMBINATION	0.120837236969297	0.412989993820105	0.999689707412342	0.999689707412342	29	POLA2,POLD2,RFC3,PRIM1,BRCA2,WRN,NSMCE2