Complex: 2y1n
CBL
- Chain: C
- Length: 1 - 906
- Included in Interaction: 52 - 435
ZAP70
- Chain: D
- Length: 1 - 619
- Included in Interaction: 289 - 297
- Cbl_N: 51-175
- Cbl_N2: 179-262
- Cbl_N3: 264-349
- Prok-RING_4: 381-429
- UBA: 856-892
Mutation: COSF1971
- KMT2A genomic breakpoint: 4086+366
- KMT2A AA breakpoint: 122
- CBL genomic breakpoint: 1808-5749
- CBL AA breakpoint: 1916
Other interactions affected by fusion KMT2A-CBL
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Reaction:
- ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
Author Description:
- Structure of c-Cbl-ZAP-70 peptide complex
Citation:
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