SUID	annotation.Taxon	AverageShortestPathLength	Betweenness	BetweennessCentrality	bg.annotation.DbId	bg.annotation.DbRelease	bg.annotation.Description	bg.annotation.EntityType	bg.annotation.GO	bg.annotation.ID	bg.annotation.InputName	bg.annotation.IsSeed	bg.annotation.KEGG	bg.annotation.Name	bg.annotation.SourceOrganism	bg.annotation.XNames	Closeness	ClosenessCentrality	ClusteringCoefficient	Degree	Eccentricity	Eigenvector	IsSingleNode	LAC	Matching.Attribute	name	NeighborhoodConnectivity	Network	NumberOfDirectedEdges	NumberOfUndirectedEdges	PartnerOfMultiEdgedNodePairs	Radiality	selected	SelfLoops	shared name	Stress	Subgragh	TopologicalCoefficient
787651	taxon:9606	1.82479912	116889.606	0.05709037	179011	1902	neurotrophic receptor tyrosine kinase 1	gene	biological_process-&-1&-GO:0007611-&&-learning or memory-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0021553-&&-olfactory nerve development-%%-GO:0009314-&&-response to radiation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0050966-&&-detection of mechanical stimulus involved in sensory perception of pain-%%-GO:0007411-&&-axon guidance-%%-GO:0045471-&&-response to ethanol-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0051599-&&-response to hydrostatic pressure-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0042493-&&-response to drug-%%-GO:0061368-&&-behavioral response to formalin induced pain-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0042490-&&-mechanoreceptor differentiation-%%-GO:0060385-&&-axonogenesis involved in innervation-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0010623-&&-programmed cell death involved in cell development-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0007568-&&-aging-%%-GO:0030183-&&-B cell differentiation-%%-GO:0007623-&&-circadian rhythm-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048678-&&-response to axon injury-%%-GO:0014823-&&-response to activity-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0000186-&&-activation of MAPKK activity|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0009986-&&-cell surface-%%-GO:0043234-&&-protein complex-%%-GO:0043235-&&-receptor complex-%%-GO:0005769-&&-early endosome-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005770-&&-late endosome-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0043121-&&-neurotrophin binding-%%-GO:0005166-&&-neurotrophin p75 receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0010465-&&-nerve growth factor receptor activity-%%-GO:0005004-&&-GPI-linked ephrin receptor activity-%%-GO:0019900-&&-kinase binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0048406-&&-nerve growth factor binding	G:9606:NTRK1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	NTRK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTRK1	0.646513503	0.54800553	0.02418919	1467	4	0.124869213	FALSE	49.67445055	NTRK1	NTRK1	83.58703072	373.1481419	0	1466	0	0.86253348	FALSE	1	NTRK1	67292950	Infinity	0.01395829
791992	taxon:9606	1.90641248	36884.06312	0.05254981	182757	1902	amyloid beta precursor protein	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0006417-&&-regulation of translation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0007626-&&-locomotory behavior-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0006897-&&-endocytosis-%%-GO:0008542-&&-visual learning-%%-GO:0016358-&&-dendrite development-%%-GO:0007176-&&-regulation of epidermal growth factor-activated receptor activity-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0048669-&&-collateral sprouting in absence of injury-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0016322-&&-neuron remodeling-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007611-&&-learning or memory-%%-GO:0007409-&&-axonogenesis-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0007617-&&-mating behavior-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0050803-&&-regulation of synapse structure or activity-%%-GO:0071874-&&-cellular response to norepinephrine stimulus-%%-GO:0006979-&&-response to oxidative stress-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0051563-&&-smooth endoplasmic reticulum calcium ion homeostasis-%%-GO:0010288-&&-response to lead ion-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031175-&&-neuron projection development-%%-GO:0016199-&&-axon midline choice point recognition-%%-GO:0008088-&&-axo-dendritic transport-%%-GO:0051124-&&-synaptic growth at neuromuscular junction-%%-GO:0030900-&&-forebrain development-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0001967-&&-suckling behavior-%%-GO:0007155-&&-cell adhesion-%%-GO:0050808-&&-synapse organization-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0009987-&&-cellular process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1990761-&&-growth cone lamellipodium-%%-GO:0045121-&&-membrane raft-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043197-&&-dendritic spine-%%-GO:1990812-&&-growth cone filopodium-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0043195-&&-terminal bouton-%%-GO:0005768-&&-endosome-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005576-&&-extracellular region-%%-GO:0031904-&&-endosome lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009986-&&-cell surface-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0045177-&&-apical part of cell-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030424-&&-axon-%%-GO:0097449-&&-astrocyte projection-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0044304-&&-main axon-%%-GO:0051233-&&-spindle midzone-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051425-&&-PTB domain binding-%%-GO:0070851-&&-growth factor receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0046914-&&-transition metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0008201-&&-heparin binding	G:9606:APP			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04726-&&-Serotonergic synapse	APP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APP	0.56044724	0.52454545	0.01466175	1007	4	0.058143668	FALSE	26.82471264	APP	APP	67.75124378	98.07988226	0	1006	0	0.84893125	FALSE	1	APP	48533772	Infinity	0.01147525
788708	taxon:9606	1.92122262	54676.73287	0.03639996	177146	1902	tumor protein p53	gene	biological_process-&-1&-GO:0010332-&&-response to gamma radiation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0051097-&&-negative regulation of helicase activity-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0008283-&&-cell proliferation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0051262-&&-protein tetramerization-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0097252-&&-oligodendrocyte apoptotic process-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006284-&&-base-excision repair-%%-GO:0048512-&&-circadian behavior-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0090399-&&-replicative senescence-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0031497-&&-chromatin assembly-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0008104-&&-protein localization-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0090403-&&-oxidative stress-induced premature senescence-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0046677-&&-response to antibiotic-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006983-&&-ER overload response-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0070245-&&-positive regulation of thymocyte apoptotic process-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010165-&&-response to X-ray-%%-GO:0007569-&&-cell aging-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005657-&&-replication fork-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0016605-&&-PML body-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0002020-&&-protease binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0043621-&&-protein self-association	G:9606:TP53	TP53	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05216-&&-Thyroid cancer-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04216-&&-Ferroptosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TP53	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53	0.592319055	0.52050189	0.03374014	944	4	0.094962254	FALSE	47.4491018	TP53	TP53	96.14118896	219.1641499	0	943	0	0.8464629	FALSE	1	TP53	41204990	Infinity	0.01630954
792787	taxon:9606	1.91318733	30631.36666	0.04269861	181367	1902	epidermal growth factor receptor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0021795-&&-cerebral cortex cell migration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0016101-&&-diterpenoid metabolic process-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0001503-&&-ossification-%%-GO:0007494-&&-midgut development-%%-GO:0030324-&&-lung development-%%-GO:0042060-&&-wound healing-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0007435-&&-salivary gland morphogenesis-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:1903800-&&-positive regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0033590-&&-response to cobalamin-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0035690-&&-cellular response to drug-%%-GO:0033594-&&-response to hydroxyisoflavone-%%-GO:0007165-&&-signal transduction-%%-GO:0043586-&&-tongue development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051592-&&-response to calcium ion-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:1900020-&&-positive regulation of protein kinase C activity-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0048143-&&-astrocyte activation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0010960-&&-magnesium ion homeostasis-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0001942-&&-hair follicle development-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0061024-&&-membrane organization-%%-GO:0097421-&&-liver regeneration-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006950-&&-response to stress-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0042743-&&-hydrogen peroxide metabolic process-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0070141-&&-response to UV-A-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0042698-&&-ovulation cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060571-&&-morphogenesis of an epithelial fold-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:1905208-&&-negative regulation of cardiocyte differentiation-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0007611-&&-learning or memory-%%-GO:0051205-&&-protein insertion into membrane-%%-GO:0043006-&&-activation of phospholipase A2 activity by calcium-mediated signaling-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0008283-&&-cell proliferation-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0007623-&&-circadian rhythm-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006412-&&-translation-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:1902722-&&-positive regulation of prolactin secretion-%%-GO:0045739-&&-positive regulation of DNA repair|cellular_component-&-1&-GO:0097489-&&-multivesicular body, internal vesicle lumen-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0043235-&&-receptor complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0031965-&&-nuclear membrane-%%-GO:0045202-&&-synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0070435-&&-Shc-EGFR complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005006-&&-epidermal growth factor-activated receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0048408-&&-epidermal growth factor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0051015-&&-actin filament binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:EGFR	EGFR	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	EGFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGFR	0.56340007	0.52268797	0.02108175	932	4	0.056529615	FALSE	32.08839779	EGFR	EGFR	75.59462366	128.4205848	0	931	0	0.84780211	FALSE	1	EGFR	41576904	Infinity	0.01270937
788935	taxon:9606	1.94690405	50863.72314	0.01880816	176567	1902	cullin 3	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045842-&&-positive regulation of mitotic metaphase/anaphase transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0030030-&&-cell projection organization-%%-GO:0001831-&&-trophectodermal cellular morphogenesis-%%-GO:0007369-&&-gastrulation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0072576-&&-liver morphogenesis-%%-GO:0017145-&&-stem cell division-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0044346-&&-fibroblast apoptotic process-%%-GO:0071630-&&-ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005827-&&-polar microtubule-%%-GO:0016020-&&-membrane-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005112-&&-Notch binding-%%-GO:0031208-&&-POZ domain binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CUL3			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	CUL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL3	0.604826546	0.513636	0.04284105	910	4	0.114031389	FALSE	52.51705566	CUL3	CUL3	102.6310573	262.4511604	0	909	0	0.84218266	FALSE	1	CUL3	26278972	Infinity	0.01777393
788894	taxon:9606	1.96281708	36493.51794	0.02138319	176662	1902	exportin 1	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000055-&&-ribosomal large subunit export from nucleus-%%-GO:0000056-&&-ribosomal small subunit export from nucleus-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0000054-&&-ribosomal subunit export from nucleus-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0042493-&&-response to drug-%%-GO:0016032-&&-viral process-%%-GO:0075733-&&-intracellular transport of virus|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0015030-&&-Cajal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005642-&&-annulate lamellae-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005049-&&-nuclear export signal receptor activity	G:9606:XPO1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A	XPO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO1	0.565784832	0.50947183	0.02703737	791	4	0.065875493	FALSE	31.85145889	XPO1	XPO1	86.03929024	121.8047149	0	790	0	0.83953049	FALSE	1	XPO1	24210800	Infinity	0.01486315
792867	taxon:9606	1.94926737	41731.72525	0.02122132	181251	1902	estrogen receptor 1	gene	biological_process-&-1&-GO:0060687-&&-regulation of branching involved in prostate gland morphogenesis-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060523-&&-prostate epithelial cord elongation-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0060068-&&-vagina development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032355-&&-response to estradiol-%%-GO:0060065-&&-uterus development-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0060745-&&-mammary gland branching involved in pregnancy-%%-GO:0007165-&&-signal transduction-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0043627-&&-response to estrogen-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008584-&&-male gonad development-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060750-&&-epithelial cell proliferation involved in mammary gland duct elongation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060527-&&-prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0001547-&&-antral ovarian follicle growth-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002064-&&-epithelial cell development-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0005496-&&-steroid binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0030284-&&-estrogen receptor activity-%%-GO:0038052-&&-RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0034056-&&-estrogen response element binding	G:9606:ESR1	ESR1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	ESR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESR1	0.581580856	0.51301326	0.04158715	761	4	0.088881373	FALSE	43.57871397	ESR1	ESR1	104.9881423	179.0311106	0	760	0	0.84178877	FALSE	1	ESR1	25612074	Infinity	0.01779449
787221	taxon:9606	1.98975894	35328.80965	0.01309663	179836	1902	minichromosome maintenance complex component 2	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006260-&&-DNA replication-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0090102-&&-cochlea development-%%-GO:0006915-&&-apoptotic process-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0006268-&&-DNA unwinding involved in DNA replication|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000785-&&-chromatin-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0046872-&&-metal ion binding	G:9606:MCM2			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM2	0.586900842	0.50257344	0.05185241	733	4	0.103624038	FALSE	51.35983264	MCM2	MCM2	114.0601915	204.4786041	0	732	0	0.83504018	FALSE	1	MCM2	19800226	Infinity	0.02008994
788639	taxon:9606	1.95824799	33745.58935	0.01691253	177275	1902	ubiquitin C	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0019058-&&-viral life cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0019068-&&-virion assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0019985-&&-translesion synthesis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010992-&&-ubiquitin homeostasis-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0002020-&&-protease binding	G:9606:UBC			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	UBC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBC	0.570615439	0.51066055	0.04341534	694	3	0.072726421	FALSE	41.385	UBC	UBC	108.1921965	160.3416977	0	693	0	0.840292	FALSE	1	UBC	21519842	Infinity	0.01828994
792994	taxon:9606	1.99621869	27269.01147	0.01457893	181025	1902	fibronectin 1	gene	biological_process-&-1&-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006953-&&-acute-phase response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:2001202-&&-negative regulation of transforming growth factor-beta secretion-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:1904237-&&-positive regulation of substrate-dependent cell migration, cell attachment to substrate-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0007161-&&-calcium-independent cell-matrix adhesion-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0042060-&&-wound healing-%%-GO:0009611-&&-response to wounding-%%-GO:0033622-&&-integrin activation-%%-GO:0007155-&&-cell adhesion-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0001525-&&-angiogenesis-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005577-&&-fibrinogen complex-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005605-&&-basal lamina-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0002020-&&-protease binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0042802-&&-identical protein binding	G:9606:FN1	FN1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	FN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FN1	0.581791803	0.50094712	0.04784916	693	4	0.097140692	FALSE	44.79867257	FN1	FN1	108.4949349	176.3917824	0	692	0	0.83396355	FALSE	1	FN1	19796330	Infinity	0.01910046
793224	taxon:9606	1.97290058	17162.09432	0.02972447	180501	1902	heat shock protein 90 alpha family class B member 1	gene	biological_process-&-1&-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:1903660-&&-negative regulation of complement-dependent cytotoxicity-%%-GO:0001890-&&-placenta development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:1905323-&&-telomerase holoenzyme complex assembly-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0042220-&&-response to cocaine-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0019062-&&-virion attachment to host cell-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0009651-&&-response to salt stress-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050821-&&-protein stabilization-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0045793-&&-positive regulation of cell size|cellular_component-&-1&-GO:0031526-&&-brush border membrane-%%-GO:1990917-&&-ooplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034751-&&-aryl hydrocarbon receptor complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0016234-&&-inclusion body-%%-GO:1990913-&&-sperm head plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0019900-&&-kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032564-&&-dATP binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0030911-&&-TPR domain binding-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0002134-&&-UTP binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0017098-&&-sulfonylurea receptor binding-%%-GO:1990226-&&-histone methyltransferase binding-%%-GO:0002135-&&-CTP binding-%%-GO:0008144-&&-drug binding-%%-GO:0070182-&&-DNA polymerase binding	G:9606:HSP90AB1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSP90AB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90AB1	0.550446122	0.50686791	0.0328183	638	4	0.060962841	FALSE	36.86824324	HSP90AB1	HSP90AB1	98.59748428	95.95410026	0	637	0	0.8378499	FALSE	1	HSP90AB1	28407072	Infinity	0.01686605
789863	taxon:9606	2.00740507	20780.24973	0.00997138	174485	1902	COP9 signalosome subunit 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1990182-&&-exosomal secretion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006413-&&-translational initiation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:1903894-&&-regulation of IRE1-mediated unfolded protein response-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0000338-&&-protein deneddylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:COPS5				COPS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS5	0.569602273	0.49815556	0.05883579	622	4	0.091751091	FALSE	50.43256997	COPS5	COPS5	114.2322581	161.856214	0	621	0	0.83209915	FALSE	1	COPS5	14090880	Infinity	0.02012733
792286	taxon:9606	2.03340161	27442.94416	0.00869935	182287	1902	cyclin dependent kinase 2	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006260-&&-DNA replication-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0032298-&&-positive regulation of DNA-dependent DNA replication initiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051298-&&-centrosome duplication-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0006281-&&-DNA repair-%%-GO:0007099-&&-centriole replication-%%-GO:0010033-&&-response to organic substance-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0006813-&&-potassium ion transport-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0097124-&&-cyclin A2-CDK2 complex-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000806-&&-Y chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000805-&&-X chromosome-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005813-&&-centrosome-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0097134-&&-cyclin E1-CDK2 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005768-&&-endosome-%%-GO:0097123-&&-cyclin A1-CDK2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0097135-&&-cyclin E2-CDK2 complex|molecular_function-&-1&-GO:0035173-&&-histone kinase activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0097472-&&-cyclin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CDK2	CDK2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04934-&&-Cushing syndrome-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05226-&&-Gastric cancer	CDK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK2	0.574704407	0.49178677	0.05381297	610	4	0.088526726	FALSE	42.38186158	CDK2	CDK2	117.1694079	155.4817868	0	609	0	0.8277664	FALSE	1	CDK2	13324058	Infinity	0.02119827
787370	taxon:9606	2.02410588	17069.27971	0.01566505	179545	1902	v-myc avian myelocytomatosis viral oncogene homolog	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0035690-&&-cellular response to drug-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0045656-&&-negative regulation of monocyte differentiation-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0051276-&&-chromosome organization-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0090096-&&-positive regulation of metanephric cap mesenchymal cell proliferation-%%-GO:0070848-&&-response to growth factor-%%-GO:0015671-&&-oxygen transport-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051782-&&-negative regulation of cell division-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0042493-&&-response to drug-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034644-&&-cellular response to UV-%%-GO:0032204-&&-regulation of telomere maintenance-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0044346-&&-fibroblast apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:MYC	MYC	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	MYC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYC	0.549880014	0.4940453	0.02822911	595	3	0.050477568	FALSE	26.78156997	MYC	MYC	89.98650927	76.69405405	0	594	0	0.82931569	FALSE	1	MYC	17925904	Infinity	0.01614099
788021	taxon:9606	2.07042697	22971.92295	0.00678875	178372	1902	ring finger protein 2	gene	biological_process-&-1&-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0036353-&&-histone H2A-K119 monoubiquitination-%%-GO:0007281-&&-germ cell development-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0001739-&&-sex chromatin-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0000791-&&-euchromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0071535-&&-RING-like zinc finger domain binding	G:9606:RNF2				RNF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF2	0.566784452	0.48299216	0.04854765	584	4	0.07697323	FALSE	36.72178478	RNF2	RNF2	106.7353952	129.7769084	0	583	0	0.8215955	FALSE	1	RNF2	10919190	Infinity	0.02008689
789554	taxon:9606	2.04789664	21660.7888	0.00422203	175192	1902	cullin 7	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0001570-&&-vasculogenesis-%%-GO:0016032-&&-viral process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0007030-&&-Golgi organization-%%-GO:0006508-&&-proteolysis-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0001890-&&-placenta development|cellular_component-&-1&-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:1990393-&&-3M complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL7			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	CUL7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL7	0.576563623	0.48830589	0.05826052	576	4	0.090778358	FALSE	41.03971963	CUL7	CUL7	118.8954704	154.729412	0	575	0	0.82535056	FALSE	1	CUL7	8599358	Infinity	0.02172766
788934	taxon:9606	2.05057507	18553.02562	0.00635927	176565	1902	cullin 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990452-&&-Parkin-FBXW7-Cul1 ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05200-&&-Pathways in cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04350-&&-TGF-beta signaling pathway	CUL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL1	0.567988669	0.48766808	0.07164612	561	4	0.091458984	FALSE	52.07474227	CUL1	CUL1	122.7245081	163.2874317	0	560	0	0.82490415	FALSE	1	CUL1	10195534	Infinity	0.02244725
793024	taxon:9606	2.00740507	15982.8757	0.01495498	180878	1902	growth factor receptor bound protein 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0061024-&&-membrane organization-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0030154-&&-cell differentiation-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0031623-&&-receptor internalization-%%-GO:0016032-&&-viral process-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0016477-&&-cell migration-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007411-&&-axon guidance-%%-GO:0007568-&&-aging-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070436-&&-Grb2-EGFR complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001784-&&-phosphotyrosine binding	G:9606:GRB2	GRB2	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRB2	0.545949626	0.49815556	0.04135699	560	4	0.051308066	FALSE	33.73626374	GRB2	GRB2	100.8154122	91.44133104	0	559	0	0.83209915	FALSE	1	GRB2	18156750	Infinity	0.01756485
790906	taxon:9606	2.10225303	16230.92367	0.00506524	170724	1902	sirtuin 7	gene	biological_process-&-1&-GO:0070932-&&-histone H3 deacetylation-%%-GO:0007072-&&-positive regulation of transcription involved in exit from mitosis-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0009303-&&-rRNA transcription-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005731-&&-nucleolus organizer region|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0097372-&&-NAD-dependent histone deacetylase activity (H3-K18 specific)-%%-GO:0070403-&&-NAD+ binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:SIRT7				SIRT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT7	0.557913043	0.47568013	0.04423982	558	4	0.070419185	FALSE	32.10588235	SIRT7	SIRT7	103.3655914	97.34609158	0	558	0	0.81629116	FALSE	0	SIRT7	8725136	Infinity	0.02011186
791211	taxon:9606	2.09973216	13877.13664	0.00414973	169720	1902	cullin associated and neddylation dissociated 1	gene	biological_process-&-1&-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0030154-&&-cell differentiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:CAND1				CAND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAND1	0.562412342	0.47625122	0.07924397	538	4	0.088925622	FALSE	54.89779006	CAND1	CAND1	118.6641791	161.913811	0	537	0	0.81671131	FALSE	1	CAND1	7193154	Infinity	0.02290706
790256	taxon:9606	2.08429179	13926.81278	0.0038304	173499	1902	obscurin like 1	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0071688-&&-striated muscle myosin thick filament assembly-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0007030-&&-Golgi organization-%%-GO:0045214-&&-sarcomere organization-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0007015-&&-actin filament organization-%%-GO:0055003-&&-cardiac myofibril assembly|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031430-&&-M band-%%-GO:1990393-&&-3M complex-%%-GO:0014704-&&-intercalated disc-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005859-&&-muscle myosin complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0097493-&&-structural molecule activity conferring elasticity-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0051371-&&-muscle alpha-actinin binding	G:9606:OBSL1	OBSL1	TRUE		OBSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OBSL1	0.56340007	0.47977927	0.05768355	520	4	0.078464068	FALSE	37.61263736	OBSL1	OBSL1	115.9189189	122.4171459	0	519	0	0.8192847	FALSE	1	OBSL1	7260700	Infinity	0.0218738
787636	taxon:9606	2.01118639	16889.20597	0.00589696	179048	1902	nucleophosmin	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032071-&&-regulation of endodeoxyribonuclease activity-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0007569-&&-cell aging-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007098-&&-centrosome cycle-%%-GO:0016032-&&-viral process-%%-GO:0008104-&&-protein localization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0042255-&&-ribosome assembly-%%-GO:0046599-&&-regulation of centriole replication-%%-GO:0060699-&&-regulation of endoribonuclease activity-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0060735-&&-regulation of eIF2 alpha phosphorylation by dsRNA-%%-GO:0010826-&&-negative regulation of centrosome duplication-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0007165-&&-signal transduction-%%-GO:0051259-&&-protein oligomerization-%%-GO:1902751-&&-positive regulation of cell cycle G2/M phase transition-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006950-&&-response to stress-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0031616-&&-spindle pole centrosome-%%-GO:0005813-&&-centrosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042393-&&-histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043023-&&-ribosomal large subunit binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:NPM1				NPM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPM1	0.563598032	0.49721896	0.09448746	512	4	0.093577579	FALSE	61.44628099	NPM1	NPM1	148.9254902	166.7612949	0	511	0	0.83146894	FALSE	1	NPM1	10189322	Infinity	0.0258234
788904	taxon:9606	1.99873956	17537.79131	0.00797541	176646	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0090168-&&-Golgi reassembly-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006605-&&-protein targeting-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019901-&&-protein kinase binding	G:9606:YWHAZ			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05161-&&-Hepatitis B	YWHAZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAZ	0.558495822	0.50031531	0.07006433	512	4	0.074218333	FALSE	46.6379822	YWHAZ	YWHAZ	137.6254902	128.2384476	0	511	0	0.83354341	FALSE	1	YWHAZ	12552002	Infinity	0.02355626
787251	taxon:9606	2.08366157	13752.14672	0.00456897	179797	1902	integrin subunit alpha 4	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:1990771-&&-clathrin-dependent extracellular exosome endocytosis-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0098657-&&-import into cell-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0003366-&&-cell-matrix adhesion involved in ameboidal cell migration-%%-GO:0030183-&&-B cell differentiation-%%-GO:0050904-&&-diapedesis-%%-GO:1903238-&&-positive regulation of leukocyte tethering or rolling-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0050776-&&-regulation of immune response-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0090074-&&-negative regulation of protein homodimerization activity-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0043113-&&-receptor clustering|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034669-&&-integrin alpha4-beta7 complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001968-&&-fibronectin binding-%%-GO:0015026-&&-coreceptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0046872-&&-metal ion binding-%%-GO:1990405-&&-protein antigen binding-%%-GO:0019960-&&-C-X3-C chemokine binding	G:9606:ITGA4			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05140-&&-Leishmaniasis-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGA4	0.562609611	0.47992439	0.06555813	504	4	0.083619952	FALSE	42.53055556	ITGA4	ITGA4	125.2948207	122.4685177	0	503	0	0.81938974	FALSE	1	ITGA4	9035276	Infinity	0.02355571
788860	taxon:9606	2.00047266	15934.57978	0.00831711	176743	1902	valosin containing protein	gene	biological_process-&-1&-GO:0034214-&&-protein hexamerization-%%-GO:0036503-&&-ERAD pathway-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006734-&&-NADH metabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1903007-&&-positive regulation of Lys63-specific deubiquitinase activity-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0070842-&&-aggresome assembly-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1903006-&&-positive regulation of protein K63-linked deubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:1903862-&&-positive regulation of oxidative phosphorylation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:2000158-&&-positive regulation of ubiquitin-specific protease activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0010918-&&-positive regulation of mitochondrial membrane potential-%%-GO:0019079-&&-viral genome replication-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0072389-&&-flavin adenine dinucleotide catabolic process-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006479-&&-protein methylation-%%-GO:0006457-&&-protein folding-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006914-&&-autophagy-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:1903715-&&-regulation of aerobic respiration|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990730-&&-VCP-NSFL1C complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0035800-&&-deubiquitinase activator activity-%%-GO:1904288-&&-BAT3 complex binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043531-&&-ADP binding-%%-GO:0044389-&&-ubiquitin-like protein ligase binding-%%-GO:1990381-&&-ubiquitin-specific protease binding	G:9606:VCP			KEGG-&-1&-hsa05134-&&-Legionellosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	VCP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCP	0.549880014	0.49988186	0.05444826	488	4	0.060562298	FALSE	36.76450512	VCP	VCP	124.9032922	93.53945535	0	487	0	0.83325456	FALSE	1	VCP	11514990	Infinity	0.02132477
791705	taxon:9606	2.08507957	12707.0222	0.00481407	167303	1902	coiled-coil domain containing 8	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0010923-&&-negative regulation of phosphatase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:1990393-&&-3M complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC8				CCDC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC8	0.553294239	0.47959801	0.04632229	474	4	0.065947227	FALSE	30.36334405	CCDC8	CCDC8	112.9724576	81.20130117	0	473	0	0.81915341	FALSE	1	CCDC8	7780660	Infinity	0.02118088
792825	taxon:9606	2.05829526	13215.43002	0.00719502	181302	1902	E1A binding protein p300	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0007507-&&-heart development-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0090043-&&-regulation of tubulin deacetylation-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0007399-&&-nervous system development-%%-GO:0006990-&&-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006473-&&-protein acetylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007623-&&-circadian rhythm-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0030324-&&-lung development-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0001756-&&-somitogenesis-%%-GO:0043627-&&-response to estrogen-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0030220-&&-platelet formation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030183-&&-B cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043969-&&-histone H2B acetylation-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0018076-&&-N-terminal peptidyl-lysine acetylation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0034212-&&-peptide N-acetyltransferase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0016746-&&-transferase activity, transferring acyl groups-%%-GO:0061733-&&-peptide-lysine-N-acetyltransferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0097157-&&-pre-mRNA intronic binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004468-&&-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:EP300			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04916-&&-Melanogenesis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	EP300	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EP300	0.547066849	0.48583895	0.06768845	458	4	0.052439794	FALSE	40.57857143	EP300	EP300	119.2938597	106.3886288	0	457	0	0.82361746	FALSE	1	EP300	10460294	Infinity	0.02159516
790508	taxon:9606	2.11328187	11898.8384	0.00730992	172653	1902	F-box protein 6	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0006281-&&-DNA repair-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006516-&&-glycoprotein catabolic process|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:FBXO6			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	FBXO6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO6	0.548188653	0.47319764	0.04158473	456	4	0.058462147	FALSE	25.33797909	FBXO6	FBXO6	103.9210526	68.09681418	0	456	0	0.81445302	FALSE	0	FBXO6	9929286	Infinity	0.02012599
792269	taxon:9606	2.10965811	13535.21746	0.00448305	182315	1902	cell division cycle 5 like	gene	biological_process-&-1&-GO:1904568-&&-cellular response to wortmannin-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0071352-&&-cellular response to interleukin-2-%%-GO:1990646-&&-cellular response to prolactin-%%-GO:0030154-&&-cell differentiation-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0072422-&&-signal transduction involved in DNA damage checkpoint|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0000974-&&-Prp19 complex|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0071987-&&-WD40-repeat domain binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0001135-&&-transcription factor activity, RNA polymerase II transcription factor recruiting-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001222-&&-transcription corepressor binding	G:9606:CDC5L			KEGG-&-1&-hsa03040-&&-Spliceosome	CDC5L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC5L	0.549880014	0.47401046	0.06277408	453	4	0.060611203	FALSE	37.53691275	CDC5L	CDC5L	116.0022173	99.80909164	0	452	0	0.81505698	FALSE	1	CDC5L	7024224	Infinity	0.02228884
788855	taxon:9606	2.11139121	11657.88758	0.0039686	176745	1902	vascular cell adhesion molecule 1	gene	biological_process-&-1&-GO:0035094-&&-response to nicotine-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030183-&&-B cell differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0010043-&&-response to zinc ion-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0007568-&&-aging-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0045471-&&-response to ethanol-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0007584-&&-response to nutrient-%%-GO:0050776-&&-regulation of immune response-%%-GO:0007155-&&-cell adhesion-%%-GO:0016032-&&-viral process-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0009308-&&-amine metabolic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005902-&&-microvillus-%%-GO:0071065-&&-alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0045177-&&-apical part of cell-%%-GO:0002102-&&-podosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0042383-&&-sarcolemma-%%-GO:0030175-&&-filopodium-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0008131-&&-primary amine oxidase activity-%%-GO:0005178-&&-integrin binding	G:9606:VCAM1	VCAM1	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05144-&&-Malaria	VCAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCAM1	0.557719054	0.47362137	0.06407095	451	4	0.0770633	FALSE	36.91394659	VCAM1	VCAM1	123.2048998	102.4636558	0	450	0	0.81476813	FALSE	1	VCAM1	7743360	Infinity	0.02373633
792049	taxon:9606	2.06979675	16425.58497	0.00703699	182690	1902	BRCA1, DNA repair associated	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0000732-&&-strand displacement-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046600-&&-negative regulation of centriole replication-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043009-&&-chordate embryonic development-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006915-&&-apoptotic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0070512-&&-positive regulation of histone H4-K20 methylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0043627-&&-response to estrogen-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0007098-&&-centrosome cycle-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2000620-&&-positive regulation of histone H4-K16 acetylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006260-&&-DNA replication-%%-GO:0009048-&&-dosage compensation by inactivation of X chromosome-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0006301-&&-postreplication repair-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0031436-&&-BRCA1-BARD1 complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005694-&&-chromosome-%%-GO:0043234-&&-protein complex-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008274-&&-gamma-tubulin ring complex-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:BRCA1	BRCA1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa01524-&&-Platinum drug resistance	BRCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRCA1	0.548376068	0.48313923	0.05339105	443	4	0.050605327	FALSE	31.35314685	BRCA1	BRCA1	115.2018141	87.89259882	0	442	0	0.82170054	FALSE	1	BRCA1	9580640	Infinity	0.02111746
788723	taxon:9606	2.06680321	17585.45105	0.00604678	177116	1902	TNF receptor associated factor 6	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048468-&&-cell development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0045453-&&-bone resorption-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0001503-&&-ossification-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007254-&&-JNK cascade-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0001843-&&-neural tube closure-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0045410-&&-positive regulation of interleukin-6 biosynthetic process|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005811-&&-lipid particle-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding	G:9606:TRAF6			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05162-&&-Measles-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05133-&&-Pertussis	TRAF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF6	0.547253497	0.483839	0.04175255	433	4	0.04272557	FALSE	24.04659498	TRAF6	TRAF6	102.2111369	74.75102807	0	432	0	0.82219946	FALSE	1	TRAF6	8213850	Infinity	0.01862236
793307	taxon:9606	2.11533008	9461.118146	0.00504046	180336	1902	histone deacetylase 1	gene	biological_process-&-1&-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006476-&&-protein deacetylation-%%-GO:0061198-&&-fungiform papilla formation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0009913-&&-epidermal cell differentiation-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007596-&&-blood coagulation-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016575-&&-histone deacetylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0042733-&&-embryonic digit morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019213-&&-deacetylase activity-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:HDAC1			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis	HDAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC1	0.539703903	0.47273946	0.07049648	431	4	0.044985116	FALSE	39.0244898	HDAC1	HDAC1	110.004662	92.87806033	0	430	0	0.81411165	FALSE	1	HDAC1	7640574	Infinity	0.02120915
787026	taxon:9606	2.07988026	10989.11049	0.00361884	180209	1902	heterogeneous nuclear ribonucleoprotein U	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding	G:9606:HNRNPU			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPU	0.552722261	0.48079691	0.1158996	430	4	0.0819754	FALSE	60.09294872	HNRNPU	HNRNPU	144.4953488	145.9503608	0	430	0	0.82001996	FALSE	0	HNRNPU	6032744	Infinity	0.02670271
790146	taxon:9606	2.08413424	14865.75676	0.00431951	173778	1902	SNW domain containing 1	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0070564-&&-positive regulation of vitamin D receptor signaling pathway-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0000350-&&-generation of catalytic spliceosome for second transesterification step-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0048385-&&-regulation of retinoic acid receptor signaling pathway-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0016032-&&-viral process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0070562-&&-regulation of vitamin D receptor signaling pathway|cellular_component-&-1&-GO:0071014-&&-post-mRNA release spliceosomal complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0071146-&&-SMAD3-SMAD4 protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005112-&&-Notch binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity	G:9606:SNW1			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03040-&&-Spliceosome	SNW1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNW1	0.548376068	0.47981554	0.062816	430	4	0.055979781	FALSE	34.64482759	SNW1	SNW1	120.161215	92.80003869	0	429	0	0.81931096	FALSE	1	SNW1	6776840	Infinity	0.02229206
789279	taxon:9606	2.16606271	9803.936694	0.0027274	175838	1902	embryonic ectoderm development	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0021510-&&-spinal cord development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000011-&&-regulation of adaxial/abaxial pattern formation-%%-GO:0061087-&&-positive regulation of histone H3-K27 methylation-%%-GO:0016571-&&-histone methylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0001739-&&-sex chromatin-%%-GO:0045120-&&-pronucleus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042054-&&-histone methyltransferase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:EED				EED	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EED	0.549503255	0.46166715	0.07838391	422	4	0.06991297	FALSE	41.43288591	EED	EED	123.2619048	102.4975601	0	421	0	0.80565622	FALSE	1	EED	5034808	Infinity	0.02525615
792883	taxon:9606	2.06491256	13333.21908	0.0061456	181227	1902	EWS RNA binding protein 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0042802-&&-identical protein binding	G:9606:EWSR1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	EWSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EWSR1	0.542441664	0.48428201	0.05190871	420	4	0.052276451	FALSE	30.3503937	EWSR1	EWSR1	121.5909091	71.15162289	0	419	0	0.82251457	FALSE	1	EWSR1	8510660	Infinity	0.0220487
793220	taxon:9606	2.06081613	6045.970169	0.01794271	180508	1902	heat shock protein family B (small) member 1	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070527-&&-platelet aggregation-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0009615-&&-response to virus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:2001028-&&-positive regulation of endothelial cell chemotaxis-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0099641-&&-anterograde axonal protein transport-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005819-&&-spindle-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0008426-&&-protein kinase C inhibitor activity-%%-GO:0042802-&&-identical protein binding	G:9606:HSPB1	HSPB1	TRUE	KEGG-&-1&-hsa05146-&&-Amoebiasis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04370-&&-VEGF signaling pathway	HSPB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPB1	0.526592252	0.48524465	0.03335762	415	4	0.037323073	FALSE	25.64571429	HSPB1	HSPB1	100.7336562	41.97236016	0	414	0	0.82319731	FALSE	1	HSPB1	16338862	Infinity	0.01829853
789529	taxon:9606	2.06822121	13829.45223	0.00382251	175255	1902	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006284-&&-base-excision repair-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0030154-&&-cell differentiation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:HUWE1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HUWE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HUWE1	0.552151463	0.48350728	0.07221826	406	4	0.065573588	FALSE	36.7605178	HUWE1	HUWE1	135.8069307	97.49581573	0	405	0	0.82196313	FALSE	1	HUWE1	6268754	Infinity	0.02463349
793359	taxon:9606	2.06333701	7384.659691	0.00354736	180243	1902	heterogeneous nuclear ribonucleoprotein A1	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0051168-&&-nuclear export-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0061752-&&-telomeric repeat-containing RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding	G:9606:HNRNPA1			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA1	0.544282321	0.4846518	0.0994194	401	4	0.0682991	FALSE	51.44106464	HNRNPA1	HNRNPA1	145.3433584	104.9410013	0	400	0	0.82277717	FALSE	1	HNRNPA1	5850656	Infinity	0.02619226
788820	taxon:9606	2.08051048	13706.79146	0.00558991	176809	1902	ubiquitin conjugating enzyme E2 I	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:1903755-&&-positive regulation of SUMO transferase activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:1990356-&&-sumoylated E2 ligase complex-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000795-&&-synaptonemal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:1990234-&&-transferase complex|molecular_function-&-1&-GO:0043398-&&-HLH domain binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0071535-&&-RING-like zinc finger domain binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0061656-&&-SUMO conjugating enzyme activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2I			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa03013-&&-RNA transport-%%-hsa04064-&&-NF-kappa B signaling pathway	UBE2I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2I	0.540431267	0.48065127	0.05072241	398	4	0.04214114	FALSE	26.68852459	UBE2I	UBE2I	109.9419192	67.61218875	0	397	0	0.81991492	FALSE	1	UBE2I	7712652	Infinity	0.02020341
787446	taxon:9606	2.0630219	11877.64031	0.0059196	179422	1902	MDM2 proto-oncogene	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0045472-&&-response to ether-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007089-&&-traversing start control point of mitotic cell cycle-%%-GO:0010955-&&-negative regulation of protein processing-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0016925-&&-protein sumoylation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0016032-&&-viral process-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0042493-&&-response to drug-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0036369-&&-transcription factor catabolic process-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:1901797-&&-negative regulation of signal transduction by p53 class mediator-%%-GO:0003283-&&-atrial septum development-%%-GO:0060411-&&-cardiac septum morphogenesis-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042220-&&-response to cocaine-%%-GO:1990785-&&-response to water-immersion restraint stress-%%-GO:0009636-&&-response to toxic substance-%%-GO:0043278-&&-response to morphine-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0010039-&&-response to iron ion-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1904404-&&-response to formaldehyde-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0071494-&&-cellular response to UV-C-%%-GO:0001568-&&-blood vessel development-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0031648-&&-protein destabilization-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0071301-&&-cellular response to vitamin B1-%%-GO:0018205-&&-peptidyl-lysine modification-%%-GO:0003281-&&-ventricular septum development-%%-GO:0034504-&&-protein localization to nucleus|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005737-&&-cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0016874-&&-ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0002039-&&-p53 binding	G:9606:MDM2	MDM2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05218-&&-Melanoma-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa01524-&&-Platinum drug resistance	MDM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDM2	0.540978078	0.48472583	0.05346108	395	4	0.048095934	FALSE	29.25702811	MDM2	MDM2	118.3638677	67.58499611	0	394	0	0.82282968	FALSE	1	MDM2	7776468	Infinity	0.02131547
788865	taxon:9606	2.10398614	11681.03031	0.00496704	176732	1902	von Hippel-Lindau tumor suppressor	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006508-&&-proteolysis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:0061428-&&-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045597-&&-positive regulation of cell differentiation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030891-&&-VCB complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:VHL			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	VHL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VHL	0.541891892	0.4752883	0.05061993	385	4	0.052927811	FALSE	26.94047619	VHL	VHL	116.9373368	58.77136088	0	384	0	0.81600231	FALSE	1	VHL	7165050	Infinity	0.02206754
788040	taxon:9606	2.09831416	9536.743542	0.00254774	178319	1902	replication protein A1	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006260-&&-DNA replication-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006284-&&-base-excision repair-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0034502-&&-protein localization to chromosome-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006310-&&-DNA recombination-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006298-&&-mismatch repair-%%-GO:0006281-&&-DNA repair-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0000723-&&-telomere maintenance-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:RPA1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa03460-&&-Fanconi anemia pathway	RPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA1	0.543544561	0.47657306	0.07354076	380	4	0.056727424	FALSE	34.33079848	RPA1	RPA1	127.8492064	79.12469045	0	379	0	0.81694764	FALSE	1	RPA1	4923716	Infinity	0.02388812
789125	taxon:9606	2.17000158	4551.990299	0.00118483	176149	1902	histone cluster 1 H3 family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3F			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3F	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3F	HIST1H3F	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3F	4593174	Infinity	0.02554688
789195	taxon:9606	2.17000158	4551.990299	0.00118483	176025	1902	histone cluster 1 H3 family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3B			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3B	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3B	HIST1H3B	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3B	4593174	Infinity	0.02554688
789197	taxon:9606	2.17000158	4551.990299	0.00118483	176027	1902	histone cluster 1 H3 family member j	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3J			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3J	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3J	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3J	HIST1H3J	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3J	4593174	Infinity	0.02554688
789198	taxon:9606	2.17000158	4551.990299	0.00118483	176026	1902	histone cluster 1 H3 family member h	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3H			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3H	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3H	HIST1H3H	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3H	4593174	Infinity	0.02554688
789191	taxon:9606	2.17000158	4551.990299	0.00118483	176029	1902	histone cluster 1 H3 family member i	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3I			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3I	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3I	HIST1H3I	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3I	4593174	Infinity	0.02554688
789192	taxon:9606	2.17000158	4551.990299	0.00118483	176028	1902	histone cluster 1 H3 family member g	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3G			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3G	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3G	HIST1H3G	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3G	4593174	Infinity	0.02554688
789193	taxon:9606	2.17000158	4551.990299	0.00118483	176031	1902	histone cluster 1 H3 family member c	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3C			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3C	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3C	HIST1H3C	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3C	4593174	Infinity	0.02554688
789194	taxon:9606	2.17000158	4551.990299	0.00118483	176030	1902	histone cluster 1 H3 family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3E			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3E	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3E	HIST1H3E	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3E	4593174	Infinity	0.02554688
789187	taxon:9606	2.17000158	4551.990299	0.00118483	176033	1902	histone cluster 1 H3 family member a	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3A	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3A	HIST1H3A	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3A	4593174	Infinity	0.02554688
789188	taxon:9606	2.17000158	4551.990299	0.00118483	176032	1902	histone cluster 1 H3 family member d	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3D			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3D	0.543544561	0.46082916	0.11497872	378	4	0.060435764	FALSE	49.13432836	HIST1H3D	HIST1H3D	125.2819149	111.5127808	0	377	0	0.80499974	FALSE	1	HIST1H3D	4593174	Infinity	0.02554688
789859	taxon:9606	2.07861982	9291.197411	0.00371794	174499	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006605-&&-protein targeting-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0034766-&&-negative regulation of ion transmembrane transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:YWHAQ			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05161-&&-Hepatitis B	YWHAQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAQ	0.54006734	0.48108846	0.0649697	377	4	0.051692363	FALSE	32.21161826	YWHAQ	YWHAQ	129.9413333	66.4042288	0	376	0	0.82023003	FALSE	1	YWHAQ	6274272	Infinity	0.02372009
787956	taxon:9606	2.11044588	10538.01626	0.00340154	178512	1902	parkin RBR E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0033132-&&-negative regulation of glucokinase activity-%%-GO:0042053-&&-regulation of dopamine metabolic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:1903202-&&-negative regulation of oxidative stress-induced cell death-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0099074-&&-mitochondrion to lysosome transport-%%-GO:1900407-&&-regulation of cellular response to oxidative stress-%%-GO:0051582-&&-positive regulation of neurotransmitter uptake-%%-GO:0007417-&&-central nervous system development-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0000422-&&-mitophagy-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0010636-&&-positive regulation of mitochondrial fusion-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0036503-&&-ERAD pathway-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0000423-&&-macromitophagy-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:1905366-&&-negative regulation of intralumenal vesicle formation-%%-GO:0010637-&&-negative regulation of mitochondrial fusion-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:1903378-&&-positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:1905281-&&-positive regulation of retrograde transport, endosome to Golgi-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1902254-&&-negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0016236-&&-macroautophagy-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0031648-&&-protein destabilization-%%-GO:0055069-&&-zinc ion homeostasis-%%-GO:0071287-&&-cellular response to manganese ion-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0070050-&&-neuron cellular homeostasis-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0044314-&&-protein K27-linked ubiquitination-%%-GO:0032368-&&-regulation of lipid transport-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0070842-&&-aggresome assembly-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:1902283-&&-negative regulation of primary amine oxidase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:1902803-&&-regulation of synaptic vesicle transport-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:1905477-&&-positive regulation of protein localization to membrane-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0007612-&&-learning-%%-GO:0044828-&&-negative regulation by host of viral genome replication-%%-GO:0050821-&&-protein stabilization-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0034620-&&-cellular response to unfolded protein-%%-GO:0001964-&&-startle response-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:1902530-&&-positive regulation of protein linear polyubiquitination-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:1903542-&&-negative regulation of exosomal secretion-%%-GO:0035519-&&-protein K29-linked ubiquitination-%%-GO:0097237-&&-cellular response to toxic substance-%%-GO:1904049-&&-negative regulation of spontaneous neurotransmitter secretion-%%-GO:0042415-&&-norepinephrine metabolic process-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1903382-&&-negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:1990452-&&-Parkin-FBXW7-Cul1 ubiquitin ligase complex-%%-GO:0097413-&&-Lewy body-%%-GO:0016235-&&-aggresome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0099073-&&-mitochondrion-derived vesicle-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0071797-&&-LUBAC complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043005-&&-neuron projection-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019900-&&-kinase binding-%%-GO:1990444-&&-F-box domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0030544-&&-Hsp70 protein binding	G:9606:PARK2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	PARK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARK2	0.543176431	0.47383352	0.05845868	374	4	0.051988855	FALSE	28.81467181	PARK2	PARK2	119.7526882	70.53970028	0	373	0	0.81492569	FALSE	1	PARK2	5382296	Infinity	0.02269836
793221	taxon:9606	2.02016701	9390.704895	0.00531196	180511	1902	heat shock protein family A (Hsp70) member 8	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0061738-&&-late endosomal microautophagy-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:1902904-&&-negative regulation of supramolecular fiber organization-%%-GO:0006457-&&-protein folding-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1904589-&&-regulation of protein import-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0061635-&&-regulation of protein complex stability-%%-GO:0061741-&&-chaperone-mediated protein transport involved in chaperone-mediated autophagy-%%-GO:0061740-&&-protein targeting to lysosome involved in chaperone-mediated autophagy-%%-GO:1904764-&&-chaperone-mediated autophagy translocation complex disassembly-%%-GO:0072318-&&-clathrin coat disassembly-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0061684-&&-chaperone-mediated autophagy-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0044829-&&-positive regulation by host of viral genome replication-%%-GO:0042026-&&-protein refolding-%%-GO:0006479-&&-protein methylation-%%-GO:0061024-&&-membrane organization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005770-&&-late endosome-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0000974-&&-Prp19 complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0098575-&&-lumenal side of lysosomal membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0061202-&&-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:HSPA8			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04144-&&-Endocytosis-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa05134-&&-Legionellosis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA8	0.542808799	0.49500858	0.08165282	368	4	0.057107985	FALSE	38.78210117	HSPA8	HSPA8	156.1830601	82.98574496	0	367	0	0.82997217	FALSE	1	HSPA8	8519904	Infinity	0.02668381
788041	taxon:9606	2.09579329	7968.241783	0.00277244	178318	1902	replication protein A2	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0006284-&&-base-excision repair-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006298-&&-mismatch repair-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0019985-&&-translesion synthesis-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0000723-&&-telomere maintenance-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0034502-&&-protein localization to chromosome-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0000785-&&-chromatin-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:RPA2			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa03460-&&-Fanconi anemia pathway	RPA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA2	0.54006734	0.47714629	0.06481382	362	4	0.051318955	FALSE	28.0746888	RPA2	RPA2	121.198895	60.58993554	0	362	0	0.81736779	FALSE	0	RPA2	4894372	Infinity	0.02253503
788936	taxon:9606	2.14116906	5827.225032	0.0023183	176566	1902	cullin 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0030891-&&-VCB complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:CUL2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	CUL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL2	0.540795684	0.46703458	0.0855729	359	4	0.064469904	FALSE	38.6031746	CUL2	CUL2	132.3008357	76.64646286	0	359	0	0.80980516	FALSE	0	CUL2	4248806	Infinity	0.02596807
788541	taxon:9606	2.0595557	7702.61329	0.00614214	177469	1902	SRC proto-oncogene, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0048477-&&-oogenesis-%%-GO:0086098-&&-angiotensin-activated signaling pathway involved in heart process-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0007172-&&-signal complex assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0060491-&&-regulation of cell projection assembly-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0071393-&&-cellular response to progesterone stimulus-%%-GO:0033625-&&-positive regulation of integrin activation-%%-GO:0007165-&&-signal transduction-%%-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0022407-&&-regulation of cell-cell adhesion-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0007417-&&-central nervous system development-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0051057-&&-positive regulation of small GTPase mediated signal transduction-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0010954-&&-positive regulation of protein processing-%%-GO:0045056-&&-transcytosis-%%-GO:2001286-&&-regulation of caveolin-mediated endocytosis-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0045453-&&-bone resorption-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0060065-&&-uterus development-%%-GO:0008283-&&-cell proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0030900-&&-forebrain development-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0034332-&&-adherens junction organization-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0007049-&&-cell cycle-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0051385-&&-response to mineralocorticoid-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0042493-&&-response to drug-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0010447-&&-response to acidic pH-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0031648-&&-protein destabilization-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007411-&&-axon guidance-%%-GO:0010641-&&-positive regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0051902-&&-negative regulation of mitochondrial depolarization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0071801-&&-regulation of podosome assembly-%%-GO:0009615-&&-response to virus-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0036035-&&-osteoclast development-%%-GO:0045087-&&-innate immune response-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005770-&&-late endosome-%%-GO:0005884-&&-actin filament-%%-GO:0005764-&&-lysosome-%%-GO:0002102-&&-podosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0032587-&&-ruffle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0070851-&&-growth factor receptor binding-%%-GO:0016301-&&-kinase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0019900-&&-kinase binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0051427-&&-hormone receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005178-&&-integrin binding-%%-GO:0020037-&&-heme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:SRC			KEGG-&-1&-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05152-&&-Tuberculosis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05219-&&-Bladder cancer-%%-hsa04727-&&-GABAergic synapse-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa04540-&&-Gap junction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04915-&&-Estrogen signaling pathway	SRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRC	0.529547706	0.48554162	0.05550699	354	4	0.026451156	FALSE	25.82162162	SRC	SRC	102.8551136	57.94563704	0	353	0	0.82340738	FALSE	1	SRC	7375422	Infinity	0.01831589
789634	taxon:9606	2.13675752	11413.35631	0.00191789	175023	1902	histone deacetylase 5	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0030182-&&-neuron differentiation-%%-GO:0030183-&&-B cell differentiation-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0042113-&&-B cell activation-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0006325-&&-chromatin organization-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006954-&&-inflammatory response-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0006476-&&-protein deacetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006342-&&-chromatin silencing-%%-GO:0010830-&&-regulation of myotube differentiation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0042220-&&-response to cocaine|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001025-&&-RNA polymerase III transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0003682-&&-chromatin binding	G:9606:HDAC5			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis	HDAC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC5	0.548563611	0.46799882	0.08125356	353	4	0.065021642	FALSE	34.13651877	HDAC5	HDAC5	146.4188034	81.63371398	0	352	0	0.81054041	FALSE	1	HDAC5	4086100	Infinity	0.02850223
792630	taxon:9606	2.07011186	9649.254985	0.00446541	181687	1902	eukaryotic translation elongation factor 1 alpha 1	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0006479-&&-protein methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0098574-&&-cytoplasmic side of lysosomal membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003746-&&-translation elongation factor activity	G:9606:EEF1A1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05134-&&-Legionellosis	EEF1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1A1	0.543176431	0.48306568	0.09604585	352	4	0.067106493	FALSE	44.00766284	EEF1A1	EEF1A1	158.1085714	86.13213065	0	351	0	0.82164802	FALSE	1	EEF1A1	6741606	Infinity	0.02848033
792170	taxon:9606	2.07861982	6425.376473	0.00666879	182481	1902	androgen receptor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007548-&&-sex differentiation-%%-GO:0048638-&&-regulation of developmental growth-%%-GO:0060599-&&-lateral sprouting involved in mammary gland duct morphogenesis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030850-&&-prostate gland development-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0060748-&&-tertiary branching involved in mammary gland duct morphogenesis-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060520-&&-activation of prostate induction by androgen receptor signaling pathway-%%-GO:0060571-&&-morphogenesis of an epithelial fold-%%-GO:0060769-&&-positive regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0016049-&&-cell growth-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0048645-&&-animal organ formation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0003073-&&-regulation of systemic arterial blood pressure-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0007338-&&-single fertilization-%%-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0019102-&&-male somatic sex determination-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0008283-&&-cell proliferation-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0051259-&&-protein oligomerization-%%-GO:0060742-&&-epithelial cell differentiation involved in prostate gland development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0060736-&&-prostate gland growth-%%-GO:0006810-&&-transport-%%-GO:0045720-&&-negative regulation of integrin biosynthetic process-%%-GO:0048808-&&-male genitalia morphogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090003-&&-regulation of establishment of protein localization to plasma membrane-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045726-&&-positive regulation of integrin biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004882-&&-androgen receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005497-&&-androgen binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0070974-&&-POU domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0051117-&&-ATPase binding	G:9606:AR	AR	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05200-&&-Pathways in cancer	AR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AR	0.529547706	0.48108846	0.05288494	346	4	0.031148778	FALSE	26.59574468	AR	AR	109.6715116	51.41989868	0	345	0	0.82023003	FALSE	1	AR	7476992	Infinity	0.01993137
791918	taxon:9606	2.0679061	7083.654228	0.00807408	182878	1902	AKT serine/threonine kinase 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0035655-&&-interleukin-18-mediated signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0001893-&&-maternal placenta development-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0006954-&&-inflammatory response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1901976-&&-regulation of cell cycle checkpoint-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0100002-&&-negative regulation of protein kinase activity by protein phosphorylation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0031929-&&-TOR signaling-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0030168-&&-platelet activation-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0015758-&&-glucose transport-%%-GO:0007165-&&-signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060709-&&-glycogen cell differentiation involved in embryonic placenta development-%%-GO:0030030-&&-cell projection organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0031999-&&-negative regulation of fatty acid beta-oxidation-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016310-&&-phosphorylation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle-%%-GO:0009408-&&-response to heat-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:0061024-&&-membrane organization-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0043276-&&-anoikis-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0007281-&&-germ cell development-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0031641-&&-regulation of myelination-%%-GO:0021510-&&-spinal cord development-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0030212-&&-hyaluronan metabolic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0070141-&&-response to UV-A-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0010975-&&-regulation of neuron projection development-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0006417-&&-regulation of translation-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:1990418-&&-response to insulin-like growth factor stimulus-%%-GO:0032079-&&-positive regulation of endodeoxyribonuclease activity-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0046622-&&-positive regulation of organ growth-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0007568-&&-aging-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0097011-&&-cellular response to granulocyte macrophage colony-stimulating factor stimulus-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0006412-&&-translation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:0072656-&&-maintenance of protein location in mitochondrion-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0010748-&&-negative regulation of plasma membrane long-chain fatty acid transport-%%-GO:0060416-&&-response to growth hormone-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0030163-&&-protein catabolic process-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0032094-&&-response to food-%%-GO:0031295-&&-T cell costimulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005819-&&-spindle-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0004672-&&-protein kinase activity	G:9606:AKT1	AKT1	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	AKT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKT1	0.529023747	0.48358095	0.04377514	337	4	0.029156141	FALSE	22.4673913	AKT1	AKT1	104.5492537	43.97340213	0	336	0	0.82201565	FALSE	1	AKT1	8275776	Infinity	0.01877053
788990	taxon:9606	2.16637782	4966.501544	0.00216558	176447	1902	cullin 5	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0008283-&&-cell proliferation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:CUL5			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis	CUL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL5	0.537533512	0.4616	0.09838751	332	4	0.061304897	FALSE	40.06410256	CUL5	CUL5	133.8614458	73.81347406	0	332	0	0.8056037	FALSE	0	CUL5	3822434	Infinity	0.02694834
789203	taxon:9606	2.09248464	6832.845298	0.00435226	176012	1902	inhibitor of nuclear factor kappa B kinase subunit gamma	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043276-&&-anoikis-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0051650-&&-establishment of vesicle localization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006955-&&-immune response-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009615-&&-response to virus-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:1990450-&&-linear polyubiquitin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding	G:9606:IKBKG			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	IKBKG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKG	0.530774322	0.47790076	0.05250575	331	4	0.035381924	FALSE	25.34715026	IKBKG	IKBKG	110.0212766	49.5441371	0	330	0	0.81791923	FALSE	1	IKBKG	5454878	Infinity	0.02027426
788898	taxon:9606	2.08665511	6755.46931	0.00288582	176648	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006605-&&-protein targeting-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0008426-&&-protein kinase C inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:YWHAG			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis	YWHAG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAG	0.533954727	0.47923588	0.07710925	329	4	0.045756646	FALSE	32.78640777	YWHAG	YWHAG	140.3333333	60.30146188	0	328	0	0.81889081	FALSE	1	YWHAG	5130778	Infinity	0.02564928
792385	taxon:9606	2.15377344	5780.660116	0.00343522	182109	1902	CREB binding protein	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006473-&&-protein acetylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0016573-&&-histone acetylation-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0018076-&&-N-terminal peptidyl-lysine acetylation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042592-&&-homeostatic process-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034644-&&-cellular response to UV-%%-GO:0048511-&&-rhythmic process-%%-GO:0007165-&&-signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042733-&&-embryonic digit morphogenesis|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043426-&&-MRF binding-%%-GO:0034212-&&-peptide N-acetyltransferase activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding	G:9606:CREBBP			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04916-&&-Melanogenesis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	CREBBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREBBP	0.528152782	0.46430139	0.08134853	327	4	0.035576247	FALSE	35.30612245	CREBBP	CREBBP	118.6	68.46878804	0	326	0	0.80770443	FALSE	1	CREBBP	5342088	Infinity	0.02347928
788897	taxon:9606	2.08381913	6112.377199	0.00351283	176649	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:1902309-&&-negative regulation of peptidyl-serine dephosphorylation-%%-GO:0001764-&&-neuron migration-%%-GO:0021766-&&-hippocampus development-%%-GO:0061024-&&-membrane organization-%%-GO:0003064-&&-regulation of heart rate by hormone-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0021987-&&-cerebral cortex development-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006605-&&-protein targeting-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0016032-&&-viral process-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0021762-&&-substantia nigra development-%%-GO:0035329-&&-hippo signaling-%%-GO:0034605-&&-cellular response to heat-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005871-&&-kinesin complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0050815-&&-phosphoserine binding-%%-GO:0019899-&&-enzyme binding	G:9606:YWHAE			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis	YWHAE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAE	0.532006633	0.4798881	0.08150824	326	4	0.049814802	FALSE	35.86206897	YWHAE	YWHAE	146.8858025	59.49408888	0	325	0	0.81936348	FALSE	1	YWHAE	5799948	Infinity	0.0267486
789491	taxon:9606	2.17047424	8254.444086	0.00256209	175350	1902	inhibitor of nuclear factor kappa B kinase subunit epsilon	gene	biological_process-&-1&-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0006955-&&-immune response-%%-GO:0098586-&&-cellular response to virus-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034340-&&-response to type I interferon-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0031966-&&-mitochondrial membrane-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0008384-&&-IkappaB kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:IKBKE			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	IKBKE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKE	0.533954727	0.4607288	0.03879525	326	4	0.035949524	FALSE	17.40375587	IKBKE	IKBKE	101.9197531	40.1045399	0	325	0	0.80492096	FALSE	1	IKBKE	3918372	Infinity	0.02061943
792445	taxon:9606	2.04773909	11064.75424	0.00430342	182011	1902	catenin beta 1	gene	biological_process-&-1&-GO:0090279-&&-regulation of calcium ion import-%%-GO:1904793-&&-regulation of euchromatin binding-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0060916-&&-mesenchymal cell proliferation involved in lung development-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0003266-&&-regulation of secondary heart field cardioblast proliferation-%%-GO:0061550-&&-cranial ganglion development-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0035315-&&-hair cell differentiation-%%-GO:0060066-&&-oviduct development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061549-&&-sympathetic ganglion development-%%-GO:0001708-&&-cell fate specification-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060769-&&-positive regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048538-&&-thymus development-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0045453-&&-bone resorption-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0050808-&&-synapse organization-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0070602-&&-regulation of centromeric sister chromatid cohesion-%%-GO:0045603-&&-positive regulation of endothelial cell differentiation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0034333-&&-adherens junction assembly-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0044334-&&-canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0022009-&&-central nervous system vasculogenesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0072053-&&-renal inner medulla development-%%-GO:0044336-&&-canonical Wnt signaling pathway involved in negative regulation of apoptotic process-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:0060479-&&-lung cell differentiation-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0048469-&&-cell maturation-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0000578-&&-embryonic axis specification-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0048599-&&-oocyte development-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0061198-&&-fungiform papilla formation-%%-GO:1904501-&&-positive regulation of chromatin-mediated maintenance of transcription-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:1990791-&&-dorsal root ganglion development-%%-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0003338-&&-metanephros morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0060492-&&-lung induction-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0010909-&&-positive regulation of heparan sulfate proteoglycan biosynthetic process-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0060742-&&-epithelial cell differentiation involved in prostate gland development-%%-GO:0072054-&&-renal outer medulla development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:1904798-&&-positive regulation of core promoter binding-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0007403-&&-glial cell fate determination-%%-GO:0060440-&&-trachea formation-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0045743-&&-positive regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0030997-&&-regulation of centriole-centriole cohesion-%%-GO:0003340-&&-negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0009950-&&-dorsal/ventral axis specification-%%-GO:0030539-&&-male genitalia development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0045976-&&-negative regulation of mitotic cell cycle, embryonic-%%-GO:0035112-&&-genitalia morphogenesis-%%-GO:0072033-&&-renal vesicle formation-%%-GO:0032355-&&-response to estradiol-%%-GO:0036023-&&-embryonic skeletal limb joint morphogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0048145-&&-regulation of fibroblast proliferation-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0035411-&&-catenin import into nucleus-%%-GO:1904888-&&-cranial skeletal system development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0042493-&&-response to drug-%%-GO:0031016-&&-pancreas development-%%-GO:2000017-&&-positive regulation of determination of dorsal identity-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0007398-&&-ectoderm development-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0061324-&&-canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0060484-&&-lung-associated mesenchyme development-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:1990403-&&-embryonic brain development-%%-GO:0030902-&&-hindbrain development-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0001764-&&-neuron migration-%%-GO:0072079-&&-nephron tubule formation-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:1904954-&&-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:0072182-&&-regulation of nephron tubule epithelial cell differentiation-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0031641-&&-regulation of myelination-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0000904-&&-cell morphogenesis involved in differentiation-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0001840-&&-neural plate development|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005938-&&-cell cortex-%%-GO:0005912-&&-adherens junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0070369-&&-beta-catenin-TCF7L2 complex-%%-GO:0030054-&&-cell junction-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0016342-&&-catenin complex-%%-GO:0045177-&&-apical part of cell-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005916-&&-fascia adherens-%%-GO:0000922-&&-spindle pole-%%-GO:1990909-&&-Wnt signalosome-%%-GO:1990907-&&-beta-catenin-TCF complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016600-&&-flotillin complex-%%-GO:0005634-&&-nucleus-%%-GO:0031528-&&-microvillus membrane-%%-GO:0016020-&&-membrane-%%-GO:0034750-&&-Scrib-APC-beta-catenin complex-%%-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0019900-&&-kinase binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding	G:9606:CTNNB1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05216-&&-Thyroid cancer-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	CTNNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNB1	0.536813922	0.48834346	0.06591369	324	4	0.03955023	FALSE	24.85650224	CTNNB1	CTNNB1	138.9814815	56.8965322	0	324	0	0.82537682	FALSE	0	CTNNB1	6427824	Infinity	0.02429692
787831	taxon:9606	2.08381913	5325.979836	0.00607484	178742	1902	mitogen-activated protein kinase 1	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006915-&&-apoptotic process-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0030878-&&-thyroid gland development-%%-GO:0043627-&&-response to estrogen-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030278-&&-regulation of ossification-%%-GO:0016032-&&-viral process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0019858-&&-cytosine metabolic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048538-&&-thymus development-%%-GO:0030168-&&-platelet activation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0000189-&&-MAPK import into nucleus-%%-GO:0061308-&&-cardiac neural crest cell development involved in heart development-%%-GO:0035094-&&-response to nicotine-%%-GO:0009636-&&-response to toxic substance-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0060425-&&-lung morphogenesis-%%-GO:0007411-&&-axon guidance-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0006935-&&-chemotaxis-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0097011-&&-cellular response to granulocyte macrophage colony-stimulating factor stimulus-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0060440-&&-trachea formation-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0007611-&&-learning or memory-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0070849-&&-response to epidermal growth factor-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0060324-&&-face development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007049-&&-cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0045596-&&-negative regulation of cell differentiation|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031143-&&-pseudopodium-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043204-&&-perikaryon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0016301-&&-kinase activity	G:9606:MAPK1	MAPK1	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05132-&&-Salmonella infection-%%-hsa04720-&&-Long-term potentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05160-&&-Hepatitis C-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04520-&&-Adherens junction	MAPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK1	0.525384867	0.4798881	0.04744938	323	4	0.028369706	FALSE	23.6402439	MAPK1	MAPK1	106.8722741	41.21425143	0	322	0	0.81936348	FALSE	1	MAPK1	7134482	Infinity	0.01944857
789596	taxon:9606	2.2270364	6187.380971	0.00146933	175099	1902	PAN2 poly(A) specific ribonuclease subunit	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006397-&&-mRNA processing-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0031251-&&-PAN complex-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity-%%-GO:0005515-&&-protein binding	G:9606:PAN2			KEGG-&-1&-hsa03018-&&-RNA degradation	PAN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAN2	0.535738143	0.44902724	0.08060748	321	4	0.059226934	FALSE	32.07883817	PAN2	PAN2	122.0560748	62.55908831	0	321	0	0.79549393	FALSE	0	PAN2	2820500	Infinity	0.02660437
789973	taxon:9606	2.15267055	7360.28564	0.00146476	174214	1902	U2 small nuclear RNA auxiliary factor 2	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0000974-&&-Prp19 complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0089701-&&-U2AF-%%-GO:0000243-&&-commitment complex|molecular_function-&-1&-GO:0030628-&&-pre-mRNA 3'-splice site binding-%%-GO:0008187-&&-poly-pyrimidine tract binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:U2AF2			KEGG-&-1&-hsa03040-&&-Spliceosome	U2AF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2AF2	0.540978078	0.46453927	0.11190301	315	4	0.057666752	FALSE	41.88188976	U2AF2	U2AF2	147.8434505	92.32705748	0	314	0	0.80788824	FALSE	1	U2AF2	2856034	Infinity	0.02915981
790358	taxon:9606	2.22719395	6299.328262	0.00136683	173226	1902	SUZ12 polycomb repressive complex 2 subunit	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016571-&&-histone methylation|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0001739-&&-sex chromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0016586-&&-RSC complex-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:SUZ12				SUZ12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUZ12	0.535559265	0.44899547	0.07921098	314	4	0.047818474	FALSE	30.70869565	SUZ12	SUZ12	126.6314103	61.42890197	0	313	0	0.79546768	FALSE	1	SUZ12	2890786	Infinity	0.02752648
791331	taxon:9606	2.14337482	7475.831611	0.00274036	169121	1902	SMAD specific E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0061736-&&-engulfment of target by autophagosome-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0007398-&&-ectoderm development-%%-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0071211-&&-protein targeting to vacuole involved in autophagy-%%-GO:0061753-&&-substrate localization to autophagosome-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:1903861-&&-positive regulation of dendrite extension|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0048185-&&-activin binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0005543-&&-phospholipid binding	G:9606:SMURF1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04350-&&-TGF-beta signaling pathway	SMURF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMURF1	0.535380507	0.46655395	0.05416014	312	4	0.044539556	FALSE	23.08796296	SMURF1	SMURF1	119.1	45.8109653	0	311	0	0.80943753	FALSE	1	SMURF1	4038106	Infinity	0.02324899
788038	taxon:9606	2.16763825	5146.731976	0.00147293	178317	1902	replication protein A3	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006284-&&-base-excision repair-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006298-&&-mismatch repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005662-&&-DNA replication factor A complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding	G:9606:RPA3			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa03420-&&-Nucleotide excision repair	RPA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA3	0.533599468	0.46133159	0.07000731	312	4	0.045682129	FALSE	27.46226415	RPA3	RPA3	120.0677419	52.38085331	0	311	0	0.80539362	FALSE	1	RPA3	3023716	Infinity	0.02409483
793050	taxon:9606	2.12226249	4599.108741	0.00886431	180835	1902	glycogen synthase kinase 3 beta	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0021766-&&-hippocampus development-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:2000738-&&-positive regulation of stem cell differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007623-&&-circadian rhythm-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006611-&&-protein export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0006983-&&-ER overload response-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:0036016-&&-cellular response to interleukin-3-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0000320-&&-re-entry into mitotic cell cycle-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0007520-&&-myoblast fusion-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0014043-&&-negative regulation of neuron maturation-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:1904339-&&-negative regulation of dopaminergic neuron differentiation-%%-GO:2000077-&&-negative regulation of type B pancreatic cell development-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0044337-&&-canonical Wnt signaling pathway involved in positive regulation of apoptotic process-%%-GO:0071109-&&-superior temporal gyrus development-%%-GO:0051534-&&-negative regulation of NFAT protein import into nucleus-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:2000466-&&-negative regulation of glycogen (starch) synthase activity-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0007409-&&-axonogenesis-%%-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0016477-&&-cell migration-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0044027-&&-hypermethylation of CpG island|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0050321-&&-tau-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0002020-&&-protease binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0002039-&&-p53 binding	G:9606:GSK3B	GSK3B	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GSK3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSK3B	0.521117609	0.47119525	0.03140203	312	4	0.023241958	FALSE	17.02068966	GSK3B	GSK3B	90.2	27.72398447	0	311	0	0.81295625	FALSE	1	GSK3B	8386796	Infinity	0.01719979
787181	taxon:9606	2.09626595	4939.265224	0.00390781	179909	1902	SMAD family member 3	gene	biological_process-&-1&-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0007492-&&-endoderm development-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0030878-&&-thyroid gland development-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0051098-&&-regulation of binding-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:1903243-&&-negative regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0001889-&&-liver development-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0048589-&&-developmental growth-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0061767-&&-negative regulation of lung blood pressure-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0050821-&&-protein stabilization-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060290-&&-transdifferentiation-%%-GO:0019049-&&-evasion or tolerance of host defenses by virus-%%-GO:0006955-&&-immune response-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050776-&&-regulation of immune response-%%-GO:0048340-&&-paraxial mesoderm morphogenesis-%%-GO:0010694-&&-positive regulation of alkaline phosphatase activity-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006810-&&-transport-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0001707-&&-mesoderm formation-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0002520-&&-immune system development-%%-GO:0032916-&&-positive regulation of transforming growth factor beta3 production-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:1901203-&&-positive regulation of extracellular matrix assembly-%%-GO:0051481-&&-negative regulation of cytosolic calcium ion concentration-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0001756-&&-somitogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0038092-&&-nodal signaling pathway-%%-GO:0002076-&&-osteoblast development-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0060039-&&-pericardium development-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0001657-&&-ureteric bud development-%%-GO:0042110-&&-T cell activation-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0042060-&&-wound healing-%%-GO:0045930-&&-negative regulation of mitotic cell cycle|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0071144-&&-SMAD2-SMAD3 protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000988-&&-transcription factor activity, protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding	G:9606:SMAD3	SMAD3	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SMAD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD3	0.525901639	0.47703871	0.05959866	302	4	0.028093956	FALSE	25.20359281	SMAD3	SMAD3	113.38	45.74929164	0	301	0	0.81728901	FALSE	1	SMAD3	5102986	Infinity	0.02083303
792197	taxon:9606	2.12856468	5410.032228	0.0030679	182445	1902	arrestin beta 2	gene	biological_process-&-1&-GO:0002032-&&-desensitization of G-protein coupled receptor protein signaling pathway by arrestin-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0007628-&&-adult walking behavior-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway-%%-GO:0042699-&&-follicle-stimulating hormone signaling pathway-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030168-&&-platelet activation-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:0007420-&&-brain development-%%-GO:0045953-&&-negative regulation of natural killer cell mediated cytotoxicity-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0031623-&&-receptor internalization-%%-GO:0034392-&&-negative regulation of smooth muscle cell apoptotic process-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061024-&&-membrane organization-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0032226-&&-positive regulation of synaptic transmission, dopaminergic-%%-GO:0007212-&&-dopamine receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0031826-&&-type 2A serotonin receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0031859-&&-platelet activating factor receptor binding-%%-GO:0031701-&&-angiotensin receptor binding-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0031762-&&-follicle-stimulating hormone receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0031691-&&-alpha-1A adrenergic receptor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0031692-&&-alpha-1B adrenergic receptor binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:ARRB2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04926-&&-Relaxin signaling pathway	ARRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRB2	0.533422015	0.46980015	0.07482784	302	4	0.050536953	FALSE	28.12385321	ARRB2	ARRB2	133.8443709	50.43122303	0	302	0	0.81190589	FALSE	0	ARRB2	4558486	Infinity	0.02558849
792030	taxon:9606	2.2190011	3867.153339	0.0016808	182714	1902	BMI1 proto-oncogene, polycomb ring finger	gene	biological_process-&-1&-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007379-&&-segment specification-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030097-&&-hemopoiesis-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0071535-&&-RING-like zinc finger domain binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:BMI1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	BMI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMI1	0.526246719	0.45065322	0.05633993	301	4	0.034864146	FALSE	22.66285714	BMI1	BMI1	109.1438127	37.41321188	0	300	0	0.79683315	FALSE	1	BMI1	3402896	Infinity	0.02332133
788247	taxon:9606	2.2190011	3867.153339	0.0016808	145236	1902	COMMD3-BMI1 readthrough	gene		G:9606:COMMD3-BMI1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	COMMD3-BMI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD3-BMI1	0.526246719	0.45065322	0.05633993	301	4	0.034864146	FALSE	22.66285714	COMMD3-BMI1	COMMD3-BMI1	109.1438127	37.41321188	0	300	0	0.79683315	FALSE	1	COMMD3-BMI1	3402896	Infinity	0.02332133
792905	taxon:9606	2.11548763	5087.482304	0.00224309	181184	1902	FUS RNA binding protein	gene	biological_process-&-1&-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0071277-&&-cellular response to calcium ion|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0044327-&&-dendritic spine head-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:FUS			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	FUS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FUS	0.536275493	0.47270425	0.1094431	297	4	0.058465216	FALSE	41.27477477	FUS	FUS	166.2745763	69.0409996	0	296	0	0.81408539	FALSE	1	FUS	3866674	Infinity	0.03124683
788213	taxon:9606	2.11533008	5525.035577	0.00405531	178065	1902	RELA proto-oncogene, NF-kB subunit	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006117-&&-acetaldehyde metabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032868-&&-response to insulin-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0001889-&&-liver development-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0043200-&&-response to amino acid-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000630-&&-positive regulation of miRNA metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033590-&&-response to cobalamin-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0014040-&&-positive regulation of Schwann cell differentiation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0043278-&&-response to morphine-%%-GO:0007568-&&-aging-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0001942-&&-hair follicle development-%%-GO:0051591-&&-response to cAMP-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0006968-&&-cellular defense response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051607-&&-defense response to virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010033-&&-response to organic substance-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010224-&&-response to UV-B-%%-GO:0032570-&&-response to progesterone-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0071159-&&-NF-kappaB complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0042301-&&-phosphate ion binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0042805-&&-actinin binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0071532-&&-ankyrin repeat binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding	G:9606:RELA	RELA	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa05134-&&-Legionellosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	RELA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RELA	0.526765189	0.47273946	0.06384564	291	4	0.030524218	FALSE	25.14035088	RELA	RELA	122.1072664	43.07490661	0	290	0	0.81411165	FALSE	1	RELA	5272766	Infinity	0.02293867
787185	taxon:9606	2.14621081	4732.36902	0.0032468	179910	1902	SMAD family member 2	gene	biological_process-&-1&-GO:0035265-&&-organ growth-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1900224-&&-positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry-%%-GO:0045165-&&-cell fate commitment-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0070723-&&-response to cholesterol-%%-GO:0007369-&&-gastrulation-%%-GO:0060021-&&-palate development-%%-GO:0048340-&&-paraxial mesoderm morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0009749-&&-response to glucose-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0051098-&&-regulation of binding-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001707-&&-mesoderm formation-%%-GO:0031016-&&-pancreas development-%%-GO:0038092-&&-nodal signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0060039-&&-pericardium development-%%-GO:0001706-&&-endoderm formation-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0001657-&&-ureteric bud development-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009791-&&-post-embryonic development-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0030073-&&-insulin secretion-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007352-&&-zygotic specification of dorsal/ventral axis|cellular_component-&-1&-GO:0071144-&&-SMAD2-SMAD3 protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0032444-&&-activin responsive factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0035326-&&-enhancer binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0070410-&&-co-SMAD binding	G:9606:SMAD2	SMAD2	TRUE	KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SMAD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD2	0.523840627	0.46593745	0.04848485	288	4	0.026491709	FALSE	20.28205128	SMAD2	SMAD2	103.9965035	34.75486652	0	287	0	0.80896487	FALSE	1	SMAD2	4190114	Infinity	0.02026009
793219	taxon:9606	2.06507011	6499.638348	0.00371225	180515	1902	heat shock protein family A (Hsp70) member 4	gene	biological_process-&-1&-GO:0006986-&&-response to unfolded protein-%%-GO:0045040-&&-protein import into mitochondrial outer membrane-%%-GO:0051131-&&-chaperone-mediated protein complex assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:HSPA4			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa04530-&&-Tight junction	HSPA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA4	0.530247934	0.48424506	0.07139202	287	4	0.039909691	FALSE	25.75132275	HSPA4	HSPA4	151.5818815	44.69616739	0	287	0	0.82248831	FALSE	0	HSPA4	5721142	Infinity	0.02683753
788900	taxon:9606	2.10918544	3781.496243	0.00280172	176650	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0061024-&&-membrane organization-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035308-&&-negative regulation of protein dephosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006605-&&-protein targeting-%%-GO:0016032-&&-viral process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0050815-&&-phosphoserine binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0045296-&&-cadherin binding	G:9606:YWHAB			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05161-&&-Hepatitis B	YWHAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAB	0.522305438	0.47411668	0.0633554	286	4	0.031974159	FALSE	24.84415584	YWHAB	YWHAB	128.2711268	37.97735782	0	285	0	0.81513576	FALSE	1	YWHAB	4504532	Infinity	0.02386818
789451	taxon:9606	2.16054829	5044.659035	0.00409052	175437	1902	BCL2 associated athanogene 3	gene	biological_process-&-1&-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0007420-&&-brain development-%%-GO:0050821-&&-protein stabilization-%%-GO:0034605-&&-cellular response to heat-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0021510-&&-spinal cord development-%%-GO:0010664-&&-negative regulation of striated muscle cell apoptotic process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0097201-&&-negative regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0032403-&&-protein complex binding	G:9606:BAG3				BAG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG3	0.522305438	0.46284548	0.03583958	284	4	0.0241291	FALSE	15.80263158	BAG3	BAG3	95.13475177	26.97782611	0	283	0	0.80657528	FALSE	1	BAG3	4686616	Infinity	0.01887592
788394	taxon:9606	2.16275406	4428.452595	0.00109144	177745	1902	staufen double-stranded RNA binding protein 1	gene	biological_process-&-1&-GO:0046726-&&-positive regulation by virus of viral protein levels in host cell-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045070-&&-positive regulation of viral genome replication|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008157-&&-protein phosphatase 1 binding	G:9606:STAU1				STAU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAU1	0.535380507	0.46237342	0.10604199	282	4	0.055097569	FALSE	35.74545455	STAU1	STAU1	152.8464286	63.02243769	0	281	0	0.80620766	FALSE	1	STAU1	2249260	Infinity	0.03031323
792295	taxon:9606	2.14368993	4080.421516	0.00467118	182278	1902	cyclin dependent kinase inhibitor 1A	gene	biological_process-&-1&-GO:0051412-&&-response to corticosterone-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0050821-&&-protein stabilization-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0034605-&&-cellular response to heat-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0090399-&&-replicative senescence-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1904031-&&-positive regulation of cyclin-dependent protein kinase activity-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0060574-&&-intestinal epithelial cell maturation-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0033158-&&-regulation of protein import into nucleus, translocation-%%-GO:0090398-&&-cellular senescence-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0010165-&&-response to X-ray-%%-GO:2000278-&&-regulation of DNA biosynthetic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0070557-&&-PCNA-p21 complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019912-&&-cyclin-dependent protein kinase activating kinase activity	G:9606:CDKN1A	CDKN1A	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	CDKN1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN1A	0.521117609	0.46648537	0.0477505	277	4	0.029305559	FALSE	20.69127517	CDKN1A	CDKN1A	110.9927273	31.75710979	0	276	0	0.80938501	FALSE	1	CDKN1A	5395404	Infinity	0.02153097
788373	taxon:9606	2.20655428	3401.793824	0.00296602	177787	1902	SRSF protein kinase 2	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045087-&&-innate immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0008380-&&-RNA splicing-%%-GO:0035063-&&-nuclear speck organization-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0045787-&&-positive regulation of cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0071889-&&-14-3-3 protein binding	G:9606:SRPK2				SRPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPK2	0.519261897	0.45319529	0.04724618	277	4	0.027548291	FALSE	21.49285714	SRPK2	SRPK2	94.65818182	32.57283483	0	276	0	0.79890762	FALSE	1	SRPK2	3433020	Infinity	0.01991615
787827	taxon:9606	2.1458957	3494.511824	0.00488215	178741	1902	mitogen-activated protein kinase 3	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0006915-&&-apoptotic process-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0030878-&&-thyroid gland development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0051216-&&-cartilage development-%%-GO:0030278-&&-regulation of ossification-%%-GO:0060324-&&-face development-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048538-&&-thymus development-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0000189-&&-MAPK import into nucleus-%%-GO:0061308-&&-cardiac neural crest cell development involved in heart development-%%-GO:0031281-&&-positive regulation of cyclase activity-%%-GO:0009636-&&-response to toxic substance-%%-GO:0060425-&&-lung morphogenesis-%%-GO:0007411-&&-axon guidance-%%-GO:2000657-&&-negative regulation of apolipoprotein binding-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0060440-&&-trachea formation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0016310-&&-phosphorylation-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0019369-&&-arachidonic acid metabolic process-%%-GO:0070849-&&-response to epidermal growth factor-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005739-&&-mitochondrion-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031143-&&-pseudopodium-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004707-&&-MAP kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity	G:9606:MAPK3	MAPK3	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05152-&&-Tuberculosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05132-&&-Salmonella infection-%%-hsa04720-&&-Long-term potentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05160-&&-Hepatitis C-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04520-&&-Adherens junction	MAPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK3	0.517753389	0.46600587	0.03739237	273	4	0.021514578	FALSE	17.11290323	MAPK3	MAPK3	96.20664207	24.80132388	0	272	0	0.80901738	FALSE	1	MAPK3	5476580	Infinity	0.018697
788392	taxon:9606	2.12509847	3946.881678	0.00723854	177751	1902	signal transducer and activator of transcription 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1902728-&&-positive regulation of growth factor dependent skeletal muscle satellite cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0072540-&&-T-helper 17 cell lineage commitment-%%-GO:0007399-&&-nervous system development-%%-GO:0010730-&&-negative regulation of hydrogen peroxide biosynthetic process-%%-GO:0032355-&&-response to estradiol-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0042593-&&-glucose homeostasis-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1904685-&&-positive regulation of metalloendopeptidase activity-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0019953-&&-sexual reproduction-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016310-&&-phosphorylation-%%-GO:0001754-&&-eye photoreceptor cell differentiation-%%-GO:0007568-&&-aging-%%-GO:0044321-&&-response to leptin-%%-GO:0060259-&&-regulation of feeding behavior-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0006954-&&-inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0097009-&&-energy homeostasis-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0060019-&&-radial glial cell differentiation-%%-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0006953-&&-acute-phase response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0045471-&&-response to ethanol-%%-GO:0008283-&&-cell proliferation-%%-GO:0042755-&&-eating behavior-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0044320-&&-cellular response to leptin stimulus-%%-GO:2000637-&&-positive regulation of gene silencing by miRNA-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042493-&&-response to drug-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0090575-&&-RNA polymerase II transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0031730-&&-CCR5 chemokine receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding	G:9606:STAT3	STAT3	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	STAT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT3	0.518590365	0.47056643	0.04488503	272	4	0.020021768	FALSE	19.6328125	STAT3	STAT3	96.52962963	30.05678609	0	271	0	0.81248359	FALSE	1	STAT3	6910088	Infinity	0.01833612
788297	taxon:9606	2.10225303	6276.347648	0.0023509	177938	1902	ribosomal protein S27a	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0019058-&&-viral life cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006412-&&-translation-%%-GO:0019068-&&-virion assembly-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006413-&&-translational initiation-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0019083-&&-viral transcription-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006364-&&-rRNA processing-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS27A			KEGG-&-1&-hsa03010-&&-Ribosome	RPS27A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS27A	0.530774322	0.47568013	0.10211951	271	4	0.04880134	FALSE	35.59296482	RPS27A	RPS27A	158.9405205	58.0057895	0	270	0	0.81629116	FALSE	1	RPS27A	3991914	Infinity	0.0292432
793311	taxon:9606	2.19048369	4719.513607	0.00160597	180335	1902	histone deacetylase 2	gene	biological_process-&-1&-GO:0071300-&&-cellular response to retinoic acid-%%-GO:2000757-&&-negative regulation of peptidyl-lysine acetylation-%%-GO:0031000-&&-response to caffeine-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0061198-&&-fungiform papilla formation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0001975-&&-response to amphetamine-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0032732-&&-positive regulation of interleukin-1 production-%%-GO:0016358-&&-dendrite development-%%-GO:0009913-&&-epidermal cell differentiation-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045347-&&-negative regulation of MHC class II biosynthetic process-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0042220-&&-response to cocaine-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0061000-&&-negative regulation of dendritic spine development-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0016575-&&-histone deacetylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0035094-&&-response to nicotine-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034605-&&-cellular response to heat-%%-GO:0070301-&&-cellular response to hydrogen peroxide|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0019213-&&-deacetylase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)	G:9606:HDAC2			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05165-&&-Human papillomavirus infection	HDAC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC2	0.527631579	0.45652018	0.10733507	271	4	0.039262097	FALSE	35.07027027	HDAC2	HDAC2	142.929368	60.37678357	0	270	0	0.80158605	FALSE	1	HDAC2	3186890	Infinity	0.02927081
790284	taxon:9606	2.1855995	3167.563435	9.56E-04	173441	1902	TAR DNA binding protein	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030264-&&-nuclear fragmentation involved in apoptotic nuclear change-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0006397-&&-mRNA processing-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008380-&&-RNA splicing-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0071765-&&-nuclear inner membrane organization|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005726-&&-perichromatin fibrils-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035061-&&-interchromatin granule|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding	G:9606:TARDBP				TARDBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARDBP	0.528849324	0.45754037	0.14422271	270	4	0.057380501	FALSE	47.5320197	TARDBP	TARDBP	155.1156716	74.19396196	0	269	0	0.80240008	FALSE	1	TARDBP	1814578	Infinity	0.0315774
790235	taxon:9606	2.16952891	4062.385192	0.00233707	173556	1902	F-box and WD repeat domain containing 11	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0031648-&&-protein destabilization-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0048511-&&-rhythmic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:FBXW11			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04218-&&-Cellular senescence-%%-hsa05131-&&-Shigellosis	FBXW11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW11	0.519093851	0.46092956	0.04673003	268	4	0.027295342	FALSE	18.04166667	FBXW11	FBXW11	103.1616541	27.97355184	0	267	0	0.80507851	FALSE	1	FBXW11	3108112	Infinity	0.02059487
793334	taxon:9606	2.27398771	4779.390385	0.00177663	180306	1902	major histocompatibility complex, class I, B	gene	biological_process-&-1&-GO:0002480-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0016032-&&-viral process-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0009986-&&-cell surface-%%-GO:0042612-&&-MHC class I protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0042605-&&-peptide antigen binding-%%-GO:0005102-&&-receptor binding	G:9606:HLA-B	HLA-B	TRUE	KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	HLA-B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-B	0.517252499	0.43975611	0.03118925	267	4	0.024345236	FALSE	12.35	HLA-B	HLA-B	86.40377358	24.30774606	0	266	0	0.78766871	FALSE	1	HLA-B	2418166	Infinity	0.0198974
792888	taxon:9606	2.20088231	5470.956696	0.00152079	181215	1902	enhancer of zeste 2 polycomb repressive complex 2 subunit	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0097421-&&-liver regeneration-%%-GO:0051154-&&-negative regulation of striated muscle cell differentiation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0070314-&&-G1 to G0 transition-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045605-&&-negative regulation of epidermal cell differentiation-%%-GO:0006325-&&-chromatin organization-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0036333-&&-hepatocyte homeostasis-%%-GO:0070734-&&-histone H3-K27 methylation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0014834-&&-skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration-%%-GO:0035984-&&-cellular response to trichostatin A-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0014013-&&-regulation of gliogenesis-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0021695-&&-cerebellar cortex development-%%-GO:1904772-&&-response to tetrachloromethane-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006306-&&-DNA methylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0032355-&&-response to estradiol-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900006-&&-positive regulation of dendrite development-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0045120-&&-pronucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035098-&&-ESC/E(Z) complex|molecular_function-&-1&-GO:0070878-&&-primary miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0046976-&&-histone methyltransferase activity (H3-K27 specific)-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:EZH2			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer-%%-hsa00310-&&-Lysine degradation	EZH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EZH2	0.528675016	0.45436323	0.08779813	266	4	0.041345347	FALSE	29.75132275	EZH2	EZH2	137.3598485	48.35524904	0	265	0	0.79985295	FALSE	1	EZH2	2835270	Infinity	0.02851842
788194	taxon:9606	2.15944541	4008.538478	0.00331141	178102	1902	RB transcriptional corepressor 1	gene	biological_process-&-1&-GO:0071459-&&-protein localization to chromosome, centromeric region-%%-GO:0045842-&&-positive regulation of mitotic metaphase/anaphase transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042551-&&-neuron maturation-%%-GO:0051301-&&-cell division-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0071930-&&-negative regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034088-&&-maintenance of mitotic sister chromatid cohesion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0016032-&&-viral process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0048667-&&-cell morphogenesis involved in neuron differentiation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0034349-&&-glial cell apoptotic process-%%-GO:0071922-&&-regulation of cohesin loading-%%-GO:0031134-&&-sister chromatid biorientation-%%-GO:0048565-&&-digestive tract development-%%-GO:0071466-&&-cellular response to xenobiotic stimulus-%%-GO:0000075-&&-cell cycle checkpoint-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007070-&&-negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0090230-&&-regulation of centromere complex assembly-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0043353-&&-enucleate erythrocyte differentiation-%%-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0031175-&&-neuron projection development-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005819-&&-spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin-%%-GO:0035189-&&-Rb-E2F complex|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019900-&&-kinase binding	G:9606:RB1	RB1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05219-&&-Bladder cancer-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	RB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RB1	0.522135417	0.46308186	0.06707689	265	4	0.0276163	FALSE	25.16666667	RB1	RB1	117.5057034	40.72254493	0	264	0	0.8067591	FALSE	1	RB1	4263556	Infinity	0.0231616
792395	taxon:9606	2.13218844	3465.579341	0.00327641	182099	1902	CRK proto-oncogene, adaptor protein	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:1990859-&&-cellular response to endothelin-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0035728-&&-response to hepatocyte growth factor-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0001878-&&-response to yeast-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0045953-&&-negative regulation of natural killer cell mediated cytotoxicity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045309-&&-protein phosphorylated amino acid binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:1990782-&&-protein tyrosine kinase binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0046875-&&-ephrin receptor binding	G:9606:CRK			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	CRK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRK	0.51825525	0.4690017	0.05814751	265	4	0.021940112	FALSE	19.63358779	CRK	CRK	103.9169811	32.27332959	0	265	0	0.81130193	FALSE	0	CRK	4000220	Infinity	0.01981276
788932	taxon:9606	2.14132661	4026.551977	0.00139643	176569	1902	cullin 4B	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0007049-&&-cell cycle-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0031175-&&-neuron projection development-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042769-&&-DNA damage response, detection of DNA damage|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL4B			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03420-&&-Nucleotide excision repair	CUL4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL4B	0.530072703	0.46700022	0.11515152	265	4	0.050735399	FALSE	35.75634518	CUL4B	CUL4B	149.3358491	58.06006193	0	265	0	0.8097789	FALSE	0	CUL4B	2540688	Infinity	0.02877231
788049	taxon:9606	2.2538207	2762.06845	9.57E-04	178304	1902	ribosomal protein L10	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL10			KEGG-&-1&-hsa03010-&&-Ribosome	RPL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL10	0.522305438	0.44369102	0.16492033	263	4	0.051975187	FALSE	56.85875706	RPL10	RPL10	134.756654	80.35664409	0	263	0	0.79102988	FALSE	0	RPL10	1617756	Infinity	0.03007706
789029	taxon:9606	2.19316212	4464.189467	0.00159468	176334	1902	ubiquitin like 4A	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0071816-&&-tail-anchored membrane protein insertion into ER membrane-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0071818-&&-BAT3 complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding	G:9606:UBL4A				UBL4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBL4A	0.527284681	0.45596264	0.11296549	263	4	0.049954567	FALSE	37.55154639	UBL4A	UBL4A	130.8897338	57.46177353	0	263	0	0.80113965	FALSE	0	UBL4A	2485918	Infinity	0.02691387
791878	taxon:9606	2.15613676	4393.661763	0.00232526	182933	1902	poly(ADP-ribose) polymerase 1	gene	biological_process-&-1&-GO:0032042-&&-mitochondrial DNA metabolic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0036211-&&-protein modification process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1903376-&&-regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0071294-&&-cellular response to zinc ion-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:1904646-&&-cellular response to beta-amyloid-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0016540-&&-protein autoprocessing-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:1904044-&&-response to aldosterone-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0006302-&&-double-strand break repair-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:1990966-&&-ATP generation from poly-ADP-D-ribose-%%-GO:1904762-&&-positive regulation of myofibroblast differentiation-%%-GO:2001170-&&-negative regulation of ATP biosynthetic process-%%-GO:0043504-&&-mitochondrial DNA repair-%%-GO:0010990-&&-regulation of SMAD protein complex assembly-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0070212-&&-protein poly-ADP-ribosylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0034599-&&-cellular response to oxidative stress|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005635-&&-nuclear envelope-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0003910-&&-DNA ligase (ATP) activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0051287-&&-NAD binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:PARP1	PARP1	TRUE	KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa04210-&&-Apoptosis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis	PARP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARP1	0.527805199	0.46379247	0.10733591	262	4	0.045964211	FALSE	36.29891304	PARP1	PARP1	166.5846154	55.27173049	0	261	0	0.80731054	FALSE	1	PARP1	4076254	Infinity	0.03266139
792083	taxon:9606	2.11627541	4800.301078	0.00243734	182647	1902	clathrin heavy chain	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0051301-&&-cell division-%%-GO:1900126-&&-negative regulation of hyaluronan biosynthetic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0060236-&&-regulation of mitotic spindle organization-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0033572-&&-transferrin transport-%%-GO:0031623-&&-receptor internalization-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006914-&&-autophagy-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane|cellular_component-&-1&-GO:1990498-&&-mitotic spindle microtubule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030132-&&-clathrin coat of coated pit-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005768-&&-endosome-%%-GO:0030118-&&-clathrin coat-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0071439-&&-clathrin complex-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032051-&&-clathrin light chain binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:CLTC			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05016-&&-Huntington disease-%%-hsa04142-&&-Lysosome-%%-hsa04721-&&-Synaptic vesicle cycle	CLTC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLTC	0.526419429	0.47252829	0.08431838	262	4	0.038607381	FALSE	27.66081871	CLTC	CLTC	157.0346154	46.07069338	0	261	0	0.8139541	FALSE	1	CLTC	3934000	Infinity	0.02933438
787977	taxon:9606	2.16212384	4071.795883	0.00225035	178478	1902	proliferating cell nuclear antigen	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0031297-&&-replication fork processing-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0007507-&&-heart development-%%-GO:0044849-&&-estrous cycle-%%-GO:0097421-&&-liver regeneration-%%-GO:0000723-&&-telomere maintenance-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006298-&&-mismatch repair-%%-GO:0071548-&&-response to dexamethasone-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0019985-&&-translesion synthesis-%%-GO:1902065-&&-response to L-glutamate-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0032077-&&-positive regulation of deoxyribonuclease activity-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:1902990-&&-mitotic telomere maintenance via semi-conservative replication-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0034644-&&-cellular response to UV-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0032355-&&-response to estradiol-%%-GO:0008283-&&-cell proliferation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0046686-&&-response to cadmium ion|cellular_component-&-1&-GO:0070557-&&-PCNA-p21 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0030894-&&-replisome-%%-GO:0005657-&&-replication fork-%%-GO:0043596-&&-nuclear replication fork-%%-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0043626-&&-PCNA complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0000701-&&-purine-specific mismatch base pair DNA N-glycosylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0032139-&&-dinucleotide insertion or deletion binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030337-&&-DNA polymerase processivity factor activity-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:PCNA	PCNA	TRUE	KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa04110-&&-Cell cycle-%%-hsa03410-&&-Base excision repair-%%-hsa03030-&&-DNA replication-%%-hsa04530-&&-Tight junction-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa05161-&&-Hepatitis B	PCNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCNA	0.52247557	0.4625082	0.07839411	260	4	0.03656888	FALSE	26.425	PCNA	PCNA	142.2790698	40.82399544	0	259	0	0.80631269	FALSE	1	PCNA	3569768	Infinity	0.02809312
792983	taxon:9606	2.1044588	4560.07373	0.00323864	181041	1902	filamin A	gene	biological_process-&-1&-GO:0034394-&&-protein localization to cell surface-%%-GO:0045184-&&-establishment of protein localization-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0043113-&&-receptor clustering-%%-GO:0021987-&&-cerebral cortex development-%%-GO:1905031-&&-regulation of membrane repolarization during cardiac muscle cell action potential-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:1905000-&&-regulation of membrane repolarization during atrial cardiac muscle cell action potential-%%-GO:0060271-&&-cilium assembly-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0016479-&&-negative regulation of transcription from RNA polymerase I promoter-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0034329-&&-cell junction assembly-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0021943-&&-formation of radial glial scaffolds-%%-GO:0030168-&&-platelet activation-%%-GO:0050821-&&-protein stabilization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007195-&&-adenylate cyclase-inhibiting dopamine receptor signaling pathway-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002576-&&-platelet degranulation-%%-GO:1901381-&&-positive regulation of potassium ion transmembrane transport-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:2001046-&&-positive regulation of integrin-mediated signaling pathway-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0070527-&&-platelet aggregation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043198-&&-dendritic shaft-%%-GO:0097440-&&-apical dendrite-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031941-&&-filamentous actin-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0031012-&&-extracellular matrix-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005730-&&-nucleolus-%%-GO:0031523-&&-Myb complex-%%-GO:0016020-&&-membrane-%%-GO:0030018-&&-Z disc-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0019900-&&-kinase binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0031852-&&-mu-type opioid receptor binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0034988-&&-Fc-gamma receptor I complex binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:FLNA			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	FLNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLNA	0.525557012	0.47518155	0.09115314	260	4	0.03850124	FALSE	30.30588235	FLNA	FLNA	156.2170543	51.65228267	0	259	0	0.81592353	FALSE	1	FLNA	4745876	Infinity	0.02879751
791890	taxon:9606	2.238853	2779.577066	0.00649979	182922	1902	adrenoceptor beta 2	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0061024-&&-membrane organization-%%-GO:1901098-&&-positive regulation of autophagosome maturation-%%-GO:0007171-&&-activation of transmembrane receptor protein tyrosine kinase activity-%%-GO:0002032-&&-desensitization of G-protein coupled receptor protein signaling pathway by arrestin-%%-GO:0031649-&&-heat generation-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045986-&&-negative regulation of smooth muscle contraction-%%-GO:0002024-&&-diet induced thermogenesis-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0002025-&&-vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1904504-&&-positive regulation of lipophagy-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0040015-&&-negative regulation of multicellular organism growth-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045453-&&-bone resorption-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0007267-&&-cell-cell signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005634-&&-nucleus-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0051380-&&-norepinephrine binding-%%-GO:0004941-&&-beta2-adrenergic receptor activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0051379-&&-epinephrine binding-%%-GO:0008179-&&-adenylate cyclase binding	G:9606:ADRB2	ADRB2	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ADRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRB2	0.509368053	0.44665728	0.03079402	259	4	0.021294121	FALSE	14.11290323	ADRB2	ADRB2	83.56809339	21.31419784	0	258	0	0.7935245	FALSE	1	ADRB2	8286400	Infinity	0.01832973
787267	taxon:9606	2.15755475	3541.183432	0.00342921	179779	1902	Jun proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0031103-&&-axon regeneration-%%-GO:0034097-&&-response to cytokine-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0001889-&&-liver development-%%-GO:0042493-&&-response to drug-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0009314-&&-response to radiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0045657-&&-positive regulation of monocyte differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007612-&&-learning-%%-GO:0010941-&&-regulation of cell death-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0001525-&&-angiogenesis-%%-GO:0051365-&&-cellular response to potassium ion starvation-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0051591-&&-response to cAMP-%%-GO:0001774-&&-microglial cell activation-%%-GO:0007568-&&-aging-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007623-&&-circadian rhythm-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0035026-&&-leading edge cell differentiation-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0051899-&&-membrane depolarization-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0060395-&&-SMAD protein signal transduction|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0044212-&&-transcription regulatory region DNA binding	G:9606:JUN	JUN	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05030-&&-Cocaine addiction-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05323-&&-Rheumatoid arthritis	JUN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JUN	0.519598316	0.46348766	0.07251564	256	4	0.023399243	FALSE	23.89361702	JUN	JUN	110.3818898	38.10683927	0	255	0	0.80707421	FALSE	1	JUN	4166510	Infinity	0.02167636
792133	taxon:9606	2.09547818	5544.683081	0.0027967	182542	1902	actin beta	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001895-&&-retina homeostasis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0098974-&&-postsynaptic actin cytoskeleton organization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034329-&&-cell junction assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048013-&&-ephrin receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0097433-&&-dense body-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043209-&&-myelin sheath-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0072562-&&-blood microparticle-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex|molecular_function-&-1&-GO:0098973-&&-structural constituent of postsynaptic actin cytoskeleton-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005524-&&-ATP binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:ACTB			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma	ACTB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTB	0.528326746	0.47721805	0.08163456	256	4	0.039893202	FALSE	27.14444444	ACTB	ACTB	157.6220472	43.68858115	0	255	0	0.8174203	FALSE	1	ACTB	4395942	Infinity	0.02871455
789127	taxon:9606	2.14368993	4883.799293	0.00284158	176150	1902	beta-transducin repeat containing E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0048511-&&-rhythmic process-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0031648-&&-protein destabilization-%%-GO:0007165-&&-signal transduction-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045309-&&-protein phosphorylated amino acid binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:BTRC			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04218-&&-Cellular senescence-%%-hsa05131-&&-Shigellosis	BTRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTRC	0.519430052	0.46648537	0.05527372	256	4	0.025508085	FALSE	19.58940397	BTRC	BTRC	115.2086614	32.84449619	0	255	0	0.80938501	FALSE	1	BTRC	3709292	Infinity	0.02222362
787378	taxon:9606	2.12163227	4628.145418	0.00219831	179529	1902	myosin heavy chain 9	gene	biological_process-&-1&-GO:0030048-&&-actin filament-based movement-%%-GO:0015031-&&-protein transport-%%-GO:0030224-&&-monocyte differentiation-%%-GO:1903923-&&-positive regulation of protein processing in phagocytic vesicle-%%-GO:0070527-&&-platelet aggregation-%%-GO:0051295-&&-establishment of meiotic spindle localization-%%-GO:0001525-&&-angiogenesis-%%-GO:0032796-&&-uropod organization-%%-GO:1903919-&&-negative regulation of actin filament severing-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0000212-&&-meiotic spindle organization-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000910-&&-cytokinesis-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0030220-&&-platelet formation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0001768-&&-establishment of T cell polarity-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0007520-&&-myoblast fusion-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0043534-&&-blood vessel endothelial cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016460-&&-myosin II complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005826-&&-actomyosin contractile ring-%%-GO:0042641-&&-actomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0043234-&&-protein complex-%%-GO:0001726-&&-ruffle-%%-GO:0097513-&&-myosin II filament-%%-GO:0031012-&&-extracellular matrix-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0001772-&&-immunological synapse-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0008305-&&-integrin complex-%%-GO:0005634-&&-nucleus-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005925-&&-focal adhesion-%%-GO:0031252-&&-cell leading edge-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043531-&&-ADP binding-%%-GO:0043495-&&-protein anchor-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0003774-&&-motor activity	G:9606:MYH9			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYH9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH9	0.525212836	0.47133521	0.09395194	253	4	0.033922151	FALSE	27.70481928	MYH9	MYH9	141.4980237	49.68519498	0	253	0	0.81306129	FALSE	0	MYH9	3538140	Infinity	0.0265809
791854	taxon:9606	2.09721128	4780.77165	0.00288742	182975	1902	ABL proto-oncogene 1, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:1904528-&&-positive regulation of microtubule binding-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:1900275-&&-negative regulation of phospholipase C activity-%%-GO:0045087-&&-innate immune response-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0001922-&&-B-1 B cell homeostasis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1904531-&&-positive regulation of actin filament binding-%%-GO:0051882-&&-mitochondrial depolarization-%%-GO:0002333-&&-transitional one stage B cell differentiation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006914-&&-autophagy-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048538-&&-thymus development-%%-GO:0048668-&&-collateral sprouting-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0060563-&&-neuroepithelial cell differentiation-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:0031113-&&-regulation of microtubule polymerization-%%-GO:0030035-&&-microspike assembly-%%-GO:1903053-&&-regulation of extracellular matrix organization-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0002322-&&-B cell proliferation involved in immune response-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0001843-&&-neural tube closure-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0006979-&&-response to oxidative stress-%%-GO:1900042-&&-positive regulation of interleukin-2 secretion-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051353-&&-positive regulation of oxidoreductase activity-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006298-&&-mismatch repair-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050798-&&-activated T cell proliferation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:2000145-&&-regulation of cell motility-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0048536-&&-spleen development-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0072358-&&-cardiovascular system development-%%-GO:1902715-&&-positive regulation of interferon-gamma secretion-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0090135-&&-actin filament branching-%%-GO:0021587-&&-cerebellum morphogenesis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:1990051-&&-activation of protein kinase C activity-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0009791-&&-post-embryonic development-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0031252-&&-cell leading edge-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0004515-&&-nicotinate-nucleotide adenylyltransferase activity-%%-GO:0030145-&&-manganese ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019905-&&-syntaxin binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005102-&&-receptor binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0003677-&&-DNA binding	G:9606:ABL1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04110-&&-Cell cycle-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05131-&&-Shigellosis	ABL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABL1	0.524525834	0.47682368	0.07434538	252	4	0.027730903	FALSE	23.87096774	ABL1	ABL1	133.94	41.06726045	0	251	0	0.81713145	FALSE	1	ABL1	4040208	Infinity	0.02443196
787811	taxon:9606	2.15046479	2531.931965	0.00555081	178758	1902	protein kinase C alpha	gene	biological_process-&-1&-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0035408-&&-histone H3-T6 phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0002159-&&-desmosome assembly-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2000707-&&-positive regulation of dense core granule biogenesis-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0030168-&&-platelet activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0001525-&&-angiogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0007411-&&-axon guidance-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0045785-&&-positive regulation of cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0004698-&&-calcium-dependent protein kinase C activity-%%-GO:0035403-&&-histone kinase activity (H3-T6 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PRKCA	PRKCA	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04713-&&-Circadian entrainment-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04970-&&-Salivary secretion-%%-hsa05225-&&-Hepatocellular carcinoma	PRKCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCA	0.514432328	0.46501575	0.03816867	252	4	0.021458346	FALSE	16.60909091	PRKCA	PRKCA	103.316	21.99909944	0	251	0	0.80825587	FALSE	1	PRKCA	5889152	Infinity	0.02012081
788512	taxon:9606	2.2802899	3106.157946	0.00218019	177525	1902	SRY-box 2	gene	biological_process-&-1&-GO:0001714-&&-endodermal cell fate specification-%%-GO:0042246-&&-tissue regeneration-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001654-&&-eye development-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006325-&&-chromatin organization-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0070848-&&-response to growth factor-%%-GO:0021983-&&-pituitary gland development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0009611-&&-response to wounding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0048839-&&-inner ear development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0021984-&&-adenohypophysis development-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0021781-&&-glial cell fate commitment-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0022409-&&-positive regulation of cell-cell adhesion-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding	G:9606:SOX2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	SOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX2	0.510340439	0.43854073	0.03498795	252	4	0.018705593	FALSE	12.87301587	SOX2	SOX2	83.66	19.62197034	0	251	0	0.78661835	FALSE	1	SOX2	2681746	Infinity	0.0193904
787131	taxon:9606	2.2005672	3555.434426	0.00118158	180015	1902	interleukin enhancer binding factor 3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0051607-&&-defense response to virus-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:ILF3				ILF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILF3	0.529897588	0.4544283	0.16073973	249	4	0.058585081	FALSE	48.87234043	ILF3	ILF3	177.9558233	66.75159315	0	249	0	0.79990547	FALSE	0	ILF3	2398428	Infinity	0.03681932
787543	taxon:9606	2.06396723	5014.00568	0.0017827	162832	1902	tubulin beta class I	gene	biological_process-&-1&-GO:0051225-&&-spindle assembly-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0007017-&&-microtubule-based process-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0051301-&&-cell division-%%-GO:0009987-&&-cellular process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0044297-&&-cell body-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0042288-&&-MHC class I protein binding	G:9606:TUBB			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB	0.5314778	0.48450382	0.1085876	247	4	0.045536514	FALSE	30.51794872	TUBB	TUBB	187.3765182	49.80405215	0	247	0	0.82267213	FALSE	0	TUBB	3714956	Infinity	0.03288461
792266	taxon:9606	2.12966756	4150.449667	0.00215496	182318	1902	cyclin dependent kinase 1	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0006915-&&-apoptotic process-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0014075-&&-response to amine-%%-GO:0051301-&&-cell division-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0008283-&&-cell proliferation-%%-GO:0034501-&&-protein localization to kinetochore-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0030261-&&-chromosome condensation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0007344-&&-pronuclear fusion-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0044772-&&-mitotic cell cycle phase transition-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0014038-&&-regulation of Schwann cell differentiation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0007569-&&-cell aging-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051445-&&-regulation of meiotic cell cycle-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0046688-&&-response to copper ion-%%-GO:0048678-&&-response to axon injury-%%-GO:0006281-&&-DNA repair-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0045995-&&-regulation of embryonic development-%%-GO:0014823-&&-response to activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006260-&&-DNA replication-%%-GO:0090166-&&-Golgi disassembly-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007098-&&-centrosome cycle-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005739-&&-mitochondrion-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0035173-&&-histone kinase activity-%%-GO:0097472-&&-cyclin-dependent protein kinase activity	G:9606:CDK1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK1	0.52247557	0.46955685	0.07390432	247	4	0.033349708	FALSE	24.40384615	CDK1	CDK1	144.322449	37.33259455	0	246	0	0.81172207	FALSE	1	CDK1	3464074	Infinity	0.02732916
788400	taxon:9606	2.13155822	3636.665533	0.00278851	177736	1902	aurora kinase A	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:1900195-&&-positive regulation of oocyte maturation-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0051301-&&-cell division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007100-&&-mitotic centrosome separation-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007051-&&-spindle organization-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0097421-&&-liver regeneration-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:1990138-&&-neuron projection extension-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007057-&&-spindle assembly involved in female meiosis I-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051642-&&-centrosome localization-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046605-&&-regulation of centrosome cycle|cellular_component-&-1&-GO:0031616-&&-spindle pole centrosome-%%-GO:0005929-&&-cilium-%%-GO:0072687-&&-meiotic spindle-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0043203-&&-axon hillock-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0051233-&&-spindle midzone-%%-GO:0005813-&&-centrosome-%%-GO:0032133-&&-chromosome passenger complex-%%-GO:0045120-&&-pronucleus-%%-GO:0042585-&&-germinal vesicle-%%-GO:0072686-&&-mitotic spindle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005524-&&-ATP binding	G:9606:AURKA			KEGG-&-1&-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	AURKA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AURKA	0.522305438	0.46914037	0.05888257	247	4	0.033357766	FALSE	22.31972789	AURKA	AURKA	127.7714286	29.52210451	0	246	0	0.81140696	FALSE	1	AURKA	3614418	Infinity	0.02424656
792909	taxon:9606	2.22892705	3123.986067	0.00278556	181171	1902	FYN proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007612-&&-learning-%%-GO:0045087-&&-innate immune response-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0031295-&&-T cell costimulation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0030168-&&-platelet activation-%%-GO:1904645-&&-response to beta-amyloid-%%-GO:0016477-&&-cell migration-%%-GO:0002250-&&-adaptive immune response-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007596-&&-blood coagulation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:1902951-&&-negative regulation of dendritic spine maintenance-%%-GO:0007631-&&-feeding behavior-%%-GO:0007411-&&-axon guidance-%%-GO:1905664-&&-regulation of calcium ion import across plasma membrane-%%-GO:0006816-&&-calcium ion transport-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0007417-&&-central nervous system development-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0042110-&&-T cell activation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0001764-&&-neuron migration-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0050798-&&-activated T cell proliferation-%%-GO:0050966-&&-detection of mechanical stimulus involved in sensory perception of pain-%%-GO:0030154-&&-cell differentiation-%%-GO:0045471-&&-response to ethanol-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030900-&&-forebrain development-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0030425-&&-dendrite-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005884-&&-actin filament-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0042608-&&-T cell receptor binding-%%-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0042609-&&-CD4 receptor binding-%%-GO:0042610-&&-CD8 receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0070851-&&-growth factor receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0015631-&&-tubulin binding	G:9606:FYN			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa05416-&&-Viral myocarditis-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa05020-&&-Prion diseases-%%-hsa04520-&&-Adherens junction-%%-hsa04660-&&-T cell receptor signaling pathway	FYN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FYN	0.508077289	0.44864636	0.05666869	246	4	0.014724772	FALSE	18.20168067	FYN	FYN	83.56147541	29.93925448	0	245	0	0.79517882	FALSE	1	FYN	3112258	Infinity	0.01796492
792915	taxon:9606	2.130928	3916.190224	0.00203477	181163	1902	X-ray repair cross complementing 6	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000723-&&-telomere maintenance-%%-GO:0006310-&&-DNA recombination-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071475-&&-cellular hyperosmotic salinity response-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0097680-&&-double-strand break repair via classical nonhomologous end joining-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0070419-&&-nonhomologous end joining complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043564-&&-Ku70:Ku80 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0051575-&&-5'-deoxyribose-5-phosphate lyase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044877-&&-macromolecular complex binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:XRCC6			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining	XRCC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRCC6	0.526074123	0.46927911	0.09201916	246	4	0.042400699	FALSE	29.65882353	XRCC6	XRCC6	167.397541	44.43173131	0	245	0	0.811512	FALSE	1	XRCC6	3545000	Infinity	0.0317318
787821	taxon:9606	2.09264219	5422.87924	0.00174583	178745	1902	protein kinase, DNA-activated, catalytic polypeptide	gene	biological_process-&-1&-GO:0002326-&&-B cell lineage commitment-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0014823-&&-response to activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0007507-&&-heart development-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0002684-&&-positive regulation of immune system process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0033152-&&-immunoglobulin V(D)J recombination-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0008283-&&-cell proliferation-%%-GO:0002360-&&-T cell lineage commitment-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0097681-&&-double-strand break repair via alternative nonhomologous end joining-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016233-&&-telomere capping-%%-GO:0048536-&&-spleen development-%%-GO:2001229-&&-negative regulation of response to gamma radiation-%%-GO:0048538-&&-thymus development-%%-GO:0002328-&&-pro-B cell differentiation-%%-GO:0033153-&&-T cell receptor V(D)J recombination-%%-GO:0001756-&&-somitogenesis-%%-GO:0002638-&&-negative regulation of immunoglobulin production-%%-GO:0007420-&&-brain development-%%-GO:0031648-&&-protein destabilization-%%-GO:0006302-&&-double-strand break repair-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0048511-&&-rhythmic process-%%-GO:0072431-&&-signal transduction involved in mitotic G1 DNA damage checkpoint-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005958-&&-DNA-dependent protein kinase-DNA ligase 4 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070419-&&-nonhomologous end joining complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0004677-&&-DNA-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005524-&&-ATP binding	G:9606:PRKDC			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03450-&&-Non-homologous end-joining	PRKDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKDC	0.528152782	0.47786478	0.09884937	242	4	0.044584967	FALSE	29.16304348	PRKDC	PRKDC	186.925	45.42625333	0	241	0	0.81789297	FALSE	1	PRKDC	3701004	Infinity	0.03385021
787532	taxon:9606	2.12368048	3895.671381	0.00272792	179233	1902	protein phosphatase 1 catalytic subunit alpha	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0016311-&&-dephosphorylation-%%-GO:0051301-&&-cell division-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0030324-&&-lung development-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0036496-&&-regulation of translational initiation by eIF2 alpha dephosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0005981-&&-regulation of glycogen catabolic process-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0042587-&&-glycogen granule-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:PPP1CA			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04218-&&-Cellular senescence-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa03015-&&-mRNA surveillance pathway	PPP1CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1CA	0.522305438	0.47088063	0.07285257	241	4	0.032095574	FALSE	23.95333333	PPP1CA	PPP1CA	147.083682	35.26376122	0	240	0	0.81271992	FALSE	1	PPP1CA	3944034	Infinity	0.02763739
790056	taxon:9606	2.14825902	2817.872074	0.00308233	173985	1902	cell division cycle 37	gene	biological_process-&-1&-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0050821-&&-protein stabilization-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:0006457-&&-protein folding-%%-GO:0006605-&&-protein targeting-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:1990565-&&-HSP90-CDC37 chaperone complex|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CDC37			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	CDC37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC37	0.517252499	0.46549322	0.05569424	241	4	0.024627613	FALSE	19.65873016	CDC37	CDC37	117.0711297	27.32968822	0	240	0	0.8086235	FALSE	1	CDC37	3744922	Infinity	0.02264742
788933	taxon:9606	2.20434851	3663.190234	0.00107202	176568	1902	cullin 4A	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030853-&&-negative regulation of granulocyte differentiation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0051246-&&-regulation of protein metabolic process-%%-GO:2000819-&&-regulation of nucleotide-excision repair-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0030097-&&-hemopoiesis-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL4A			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03420-&&-Nucleotide excision repair	CUL4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL4A	0.526074123	0.45364877	0.10793178	240	4	0.042575922	FALSE	30.47976879	CUL4A	CUL4A	148.4453782	47.33357047	0	239	0	0.79927525	FALSE	1	CUL4A	2167934	Infinity	0.03075226
793364	taxon:9606	2.11501497	4901.827742	0.00111207	180233	1902	heterogeneous nuclear ribonucleoprotein K	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:1902165-&&-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0007165-&&-signal transduction-%%-GO:0045716-&&-positive regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0072369-&&-regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010467-&&-gene expression-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010988-&&-regulation of low-density lipoprotein particle clearance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0042995-&&-cell projection-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:HNRNPK			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03040-&&-Spliceosome	HNRNPK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPK	0.533422015	0.47280989	0.15161508	240	4	0.05544306	FALSE	42.09803922	HNRNPK	HNRNPK	205.1218487	67.19824196	0	239	0	0.81416417	FALSE	1	HNRNPK	2669112	Infinity	0.03809763
787223	taxon:9606	2.17866709	3715.794876	0.00107351	179833	1902	minichromosome maintenance complex component 5	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0003688-&&-DNA replication origin binding	G:9606:MCM5			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM5	0.526765189	0.45899624	0.11835027	239	4	0.045817066	FALSE	32.5027933	MCM5	MCM5	166.5313808	46.57047964	0	239	0	0.80355549	FALSE	0	MCM5	2323644	Infinity	0.03343836
789808	taxon:9606	2.10776745	3668.685558	0.0029672	174615	1902	STIP1 homology and U-box containing protein 1	gene	biological_process-&-1&-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0051604-&&-protein maturation-%%-GO:0036503-&&-ERAD pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0071218-&&-cellular response to misfolded protein-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0031943-&&-regulation of glucocorticoid metabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0090035-&&-positive regulation of chaperone-mediated protein complex assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0031371-&&-ubiquitin conjugating enzyme complex|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046332-&&-SMAD binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0030911-&&-TPR domain binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:STUB1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	STUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STUB1	0.51993517	0.47443564	0.06447114	239	4	0.023166059	FALSE	22.13475177	STUB1	STUB1	122.4936709	33.51249506	0	238	0	0.81537209	FALSE	1	STUB1	3740008	Infinity	0.02257143
790275	taxon:9606	2.21474712	3880.164055	0.00225108	173461	1902	sirtuin 1	gene	biological_process-&-1&-GO:0031937-&&-positive regulation of chromatin silencing-%%-GO:0002821-&&-positive regulation of adaptive immune response-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031648-&&-protein destabilization-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0071441-&&-negative regulation of histone H3-K14 acetylation-%%-GO:0031393-&&-negative regulation of prostaglandin biosynthetic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000012-&&-single strand break repair-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:0006364-&&-rRNA processing-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0070857-&&-regulation of bile acid biosynthetic process-%%-GO:1901984-&&-negative regulation of protein acetylation-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0044321-&&-response to leptin-%%-GO:0032071-&&-regulation of endodeoxyribonuclease activity-%%-GO:0071900-&&-regulation of protein serine/threonine kinase activity-%%-GO:0000720-&&-pyrimidine dimer repair by nucleotide-excision repair-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0034391-&&-regulation of smooth muscle cell apoptotic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006281-&&-DNA repair-%%-GO:0006343-&&-establishment of chromatin silencing-%%-GO:0010934-&&-macrophage cytokine production-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0006260-&&-DNA replication-%%-GO:0007517-&&-muscle organ development-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0018394-&&-peptidyl-lysine acetylation-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0051097-&&-negative regulation of helicase activity-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0007569-&&-cell aging-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:1990619-&&-histone H3-K9 deacetylation-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0010883-&&-regulation of lipid storage-%%-GO:0032868-&&-response to insulin-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006476-&&-protein deacetylation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:2000619-&&-negative regulation of histone H4-K16 acetylation-%%-GO:2000655-&&-negative regulation of cellular response to testosterone stimulus-%%-GO:0035356-&&-cellular triglyceride homeostasis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1904179-&&-positive regulation of adipose tissue development-%%-GO:2000481-&&-positive regulation of cAMP-dependent protein kinase activity-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0033158-&&-regulation of protein import into nucleus, translocation-%%-GO:0035358-&&-regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000111-&&-positive regulation of macrophage apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006325-&&-chromatin organization-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0006642-&&-triglyceride mobilization-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0001525-&&-angiogenesis-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061647-&&-histone H3-K9 modification-%%-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0016032-&&-viral process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0042595-&&-behavioral response to starvation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:2000757-&&-negative regulation of peptidyl-lysine acetylation-%%-GO:0006342-&&-chromatin silencing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0016605-&&-PML body-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0033553-&&-rDNA heterochromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0034979-&&-NAD-dependent protein deacetylase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0019213-&&-deacetylase activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:1990254-&&-keratin filament binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0070403-&&-NAD+ binding-%%-GO:0017136-&&-NAD-dependent histone deacetylase activity-%%-GO:0043398-&&-HLH domain binding-%%-GO:0002039-&&-p53 binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0046969-&&-NAD-dependent histone deacetylase activity (H3-K9 specific)-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:SIRT1	SIRT1	TRUE	KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	SIRT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT1	0.520441272	0.45151882	0.07491239	239	4	0.031049749	FALSE	25.30463576	SIRT1	SIRT1	129.9704641	36.67806267	0	238	0	0.79754215	FALSE	1	SIRT1	3344882	Infinity	0.0273449
792609	taxon:9606	2.23522924	3855.412475	0.0020835	165346	1902	leucine rich repeat kinase 2	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006897-&&-endocytosis-%%-GO:0035564-&&-regulation of kidney size-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway-%%-GO:0007040-&&-lysosome organization-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:2000172-&&-regulation of branching morphogenesis of a nerve-%%-GO:0021772-&&-olfactory bulb development-%%-GO:1903125-&&-negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation-%%-GO:1904887-&&-Wnt signalosome assembly-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0040012-&&-regulation of locomotion-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0014041-&&-regulation of neuron maturation-%%-GO:0010955-&&-negative regulation of protein processing-%%-GO:1905289-&&-regulation of CAMKK-AMPK signaling cascade-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0051900-&&-regulation of mitochondrial depolarization-%%-GO:0022028-&&-tangential migration from the subventricular zone to the olfactory bulb-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0046039-&&-GTP metabolic process-%%-GO:0048312-&&-intracellular distribution of mitochondria-%%-GO:1902803-&&-regulation of synaptic vesicle transport-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0070997-&&-neuron death-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007030-&&-Golgi organization-%%-GO:0016310-&&-phosphorylation-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071287-&&-cellular response to manganese ion-%%-GO:0010506-&&-regulation of autophagy-%%-GO:1905279-&&-regulation of retrograde transport, endosome to Golgi-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:1902499-&&-positive regulation of protein autoubiquitination-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0034613-&&-cellular protein localization-%%-GO:0035640-&&-exploration behavior-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0000165-&&-MAPK cascade-%%-GO:1903215-&&-negative regulation of protein targeting to mitochondrion-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:1902823-&&-negative regulation of late endosome to lysosome transport-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0007005-&&-mitochondrion organization-%%-GO:2000300-&&-regulation of synaptic vesicle exocytosis-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0090394-&&-negative regulation of excitatory postsynaptic potential-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0035751-&&-regulation of lysosomal lumen pH-%%-GO:1903217-&&-negative regulation of protein processing involved in protein targeting to mitochondrion-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0051646-&&-mitochondrion localization-%%-GO:0060161-&&-positive regulation of dopamine receptor signaling pathway-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:1902692-&&-regulation of neuroblast proliferation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0006914-&&-autophagy-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030424-&&-axon-%%-GO:0043195-&&-terminal bouton-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0044754-&&-autolysosome-%%-GO:0099400-&&-caveola neck-%%-GO:0005634-&&-nucleus-%%-GO:0016234-&&-inclusion body-%%-GO:0043025-&&-neuronal cell body-%%-GO:0043204-&&-perikaryon-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005902-&&-microvillus-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0044753-&&-amphisome-%%-GO:0070062-&&-extracellular exosome-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0097487-&&-multivesicular body, internal vesicle-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0030425-&&-dendrite-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005768-&&-endosome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005615-&&-extracellular space-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0030426-&&-growth cone-%%-GO:0098794-&&-postsynapse-%%-GO:0043005-&&-neuron projection-%%-GO:0032473-&&-cytoplasmic side of mitochondrial outer membrane-%%-GO:0030054-&&-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0003779-&&-actin binding-%%-GO:0005525-&&-GTP binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0034211-&&-GTP-dependent protein kinase activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0030276-&&-clathrin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000149-&&-SNARE binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0039706-&&-co-receptor binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0036479-&&-peroxidase inhibitor activity-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:1904713-&&-beta-catenin destruction complex binding	G:9606:LRRK2			KEGG-&-1&-hsa05012-&&-Parkinson disease	LRRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRK2	0.517252499	0.44738141	0.05658132	238	4	0.030170364	FALSE	19.58108108	LRRK2	LRRK2	117.4915254	28.36323219	0	237	0	0.79412846	FALSE	1	LRRK2	3174458	Infinity	0.02543658
792408	taxon:9606	2.17015913	1923.013053	0.00506927	182071	1902	mitogen-activated protein kinase 14	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0098586-&&-cellular response to virus-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0001890-&&-placenta development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030278-&&-regulation of ossification-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0001502-&&-cartilage condensation-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0001525-&&-angiogenesis-%%-GO:0031281-&&-positive regulation of cyclase activity-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006935-&&-chemotaxis-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0014835-&&-myoblast differentiation involved in skeletal muscle regeneration-%%-GO:0090336-&&-positive regulation of brown fat cell differentiation-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:2001184-&&-positive regulation of interleukin-12 secretion-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0051146-&&-striated muscle cell differentiation|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0051525-&&-NFAT protein binding-%%-GO:0004707-&&-MAP kinase activity	G:9606:MAPK14	MAPK14	TRUE	KEGG-&-1&-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04611-&&-Platelet activation-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK14	0.511805999	0.4607957	0.03833062	235	4	0.017658461	FALSE	15.24742268	MAPK14	MAPK14	97.34334764	18.8420105	0	234	0	0.80497348	FALSE	1	MAPK14	5027212	Infinity	0.01938432
787678	taxon:9606	2.18701749	3137.835146	0.00308671	178964	1902	phosphoinositide-3-kinase regulatory subunit 1	gene	biological_process-&-1&-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0050821-&&-protein stabilization-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0051492-&&-regulation of stress fiber assembly-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0051531-&&-NFAT protein import into nucleus-%%-GO:0034644-&&-cellular response to UV-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0050852-&&-T cell receptor signaling pathway|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0005737-&&-cytoplasm-%%-GO:0005943-&&-phosphatidylinositol 3-kinase complex, class IA-%%-GO:1990578-&&-perinuclear endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0043559-&&-insulin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0035014-&&-phosphatidylinositol 3-kinase regulator activity-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity	G:9606:PIK3R1	PIK3R1	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R1	0.513773222	0.45724371	0.07583221	234	4	0.017256679	FALSE	22.30769231	PIK3R1	PIK3R1	102.375	36.43642593	0	233	0	0.80216375	FALSE	1	PIK3R1	3574214	Infinity	0.02076135
789426	taxon:9606	2.25240271	2836.155111	5.57E-04	175515	1902	eukaryotic translation initiation factor 4A3	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0008306-&&-associative learning-%%-GO:1904574-&&-negative regulation of selenocysteine insertion sequence binding-%%-GO:0006364-&&-rRNA processing-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072715-&&-cellular response to selenite ion-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:1904570-&&-negative regulation of selenocysteine incorporation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0035640-&&-exploration behavior-%%-GO:0090394-&&-negative regulation of excitatory postsynaptic potential-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006369-&&-termination of RNA polymerase II transcription|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0035368-&&-selenocysteine insertion sequence binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0008143-&&-poly(A) binding	G:9606:EIF4A3			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	EIF4A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4A3	0.526419429	0.44397034	0.14991043	234	4	0.052038901	FALSE	41.76344086	EIF4A3	EIF4A3	166.5474138	62.14167092	0	233	0	0.79126622	FALSE	1	EIF4A3	1414034	Infinity	0.03683767
792199	taxon:9606	2.16196628	3592.316552	0.00198922	182446	1902	arrestin beta 1	gene	biological_process-&-1&-GO:0090240-&&-positive regulation of histone H4 acetylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0015031-&&-protein transport-%%-GO:0007602-&&-phototransduction-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0032717-&&-negative regulation of interleukin-8 production-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0042699-&&-follicle-stimulating hormone signaling pathway-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0030168-&&-platelet activation-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0061024-&&-membrane organization|cellular_component-&-1&-GO:0043197-&&-dendritic spine-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031143-&&-pseudopodium-%%-GO:0000785-&&-chromatin-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0031701-&&-angiotensin receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0035612-&&-AP-2 adaptor complex binding-%%-GO:0031896-&&-V2 vasopressin receptor binding-%%-GO:0045309-&&-protein phosphorylated amino acid binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0031762-&&-follicle-stimulating hormone receptor binding-%%-GO:0031691-&&-alpha-1A adrenergic receptor binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0031692-&&-alpha-1B adrenergic receptor binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding	G:9606:ARRB1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04926-&&-Relaxin signaling pathway	ARRB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRB1	0.524697416	0.4625419	0.06615362	233	4	0.034904167	FALSE	19.35	ARRB1	ARRB1	135.832618	28.11013886	0	233	0	0.80633895	FALSE	0	ARRB1	3042348	Infinity	0.02666708
792476	taxon:9606	2.25098472	4738.487877	0.00132973	181957	1902	BRCA1 associated RING domain 1	gene	biological_process-&-1&-GO:0001894-&&-tissue homeostasis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000732-&&-strand displacement-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0031441-&&-negative regulation of mRNA 3'-end processing|cellular_component-&-1&-GO:0031436-&&-BRCA1-BARD1 complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019900-&&-kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:BARD1			KEGG-&-1&-hsa03440-&&-Homologous recombination	BARD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BARD1	0.516752577	0.44425002	0.06251436	231	4	0.027378967	FALSE	19.94039735	BARD1	BARD1	117.4497817	32.66288414	0	230	0	0.79150255	FALSE	1	BARD1	2165818	Infinity	0.02589082
788787	taxon:9606	2.18827793	4402.772139	0.0018576	176903	1902	ubiquitin specific peptidase 7	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0035616-&&-histone H2B conserved C-terminal lysine deubiquitination-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0050821-&&-protein stabilization-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1904353-&&-regulation of telomere capping-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016032-&&-viral process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0002039-&&-p53 binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008134-&&-transcription factor binding	G:9606:USP7			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05203-&&-Viral carcinogenesis	USP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP7	0.521965506	0.45698034	0.05902858	231	4	0.028495807	FALSE	19.19047619	USP7	USP7	133.069869	29.77757096	0	230	0	0.80195368	FALSE	1	USP7	2836602	Infinity	0.02699202
787054	taxon:9606	2.260438	2600.681198	0.00135169	180156	1902	interferon gamma inducible protein 16	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0051607-&&-defense response to virus-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:2000117-&&-negative regulation of cysteine-type endopeptidase activity-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0006914-&&-autophagy-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:IFI16			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	IFI16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFI16	0.510340439	0.44239214	0.03782039	230	4	0.017964073	FALSE	9.875	IFI16	IFI16	87.13913043	14.59455814	0	230	0	0.789927	FALSE	0	IFI16	1833142	Infinity	0.01947336
788239	taxon:9606	2.14195683	2916.156775	0.00186691	178027	1902	SHC adaptor protein 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0007507-&&-heart development-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001525-&&-angiogenesis-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0007176-&&-regulation of epidermal growth factor-activated receptor activity-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0040008-&&-regulation of growth-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0045740-&&-positive regulation of DNA replication|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0070435-&&-Shc-EGFR complex|molecular_function-&-1&-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0048408-&&-epidermal growth factor binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005543-&&-phospholipid binding	G:9606:SHC1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SHC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHC1	0.519430052	0.46686282	0.08775794	230	4	0.02394658	FALSE	24.0942029	SHC1	SHC1	124.5877193	39.95881234	0	229	0	0.80967386	FALSE	1	SHC1	2847854	Infinity	0.0238574
789631	taxon:9606	2.11911139	4815.753252	0.00211067	175024	1902	histone deacetylase 6	gene	biological_process-&-1&-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070845-&&-polyubiquitinated misfolded protein transport-%%-GO:0016575-&&-histone deacetylation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0090035-&&-positive regulation of chaperone-mediated protein complex assembly-%%-GO:0006914-&&-autophagy-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048668-&&-collateral sprouting-%%-GO:0006476-&&-protein deacetylation-%%-GO:0051788-&&-response to misfolded protein-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0045598-&&-regulation of fat cell differentiation-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0060632-&&-regulation of microtubule-based movement-%%-GO:0032418-&&-lysosome localization-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0090042-&&-tubulin deacetylation-%%-GO:0071218-&&-cellular response to misfolded protein-%%-GO:0043241-&&-protein complex disassembly-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0070846-&&-Hsp90 deacetylation-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0070848-&&-response to growth factor-%%-GO:0010033-&&-response to organic substance-%%-GO:0035967-&&-cellular response to topologically incorrect protein-%%-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization-%%-GO:0009636-&&-response to toxic substance-%%-GO:1901300-&&-positive regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0060271-&&-cilium assembly-%%-GO:0010727-&&-negative regulation of hydrogen peroxide metabolic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0051354-&&-negative regulation of oxidoreductase activity-%%-GO:0043242-&&-negative regulation of protein complex disassembly-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0070842-&&-aggresome assembly-%%-GO:0051646-&&-mitochondrion localization-%%-GO:0007026-&&-negative regulation of microtubule depolymerization|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0016234-&&-inclusion body-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030286-&&-dynein complex-%%-GO:0005771-&&-multivesicular body-%%-GO:0016235-&&-aggresome-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola-%%-GO:0031252-&&-cell leading edge-%%-GO:0043204-&&-perikaryon-%%-GO:0030424-&&-axon-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042903-&&-tubulin deacetylase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0048156-&&-tau protein binding	G:9606:HDAC6			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC6	0.526419429	0.47189591	0.0723008	230	4	0.03433371	FALSE	22.11976048	HDAC6	HDAC6	152.8245614	33.7161523	0	229	0	0.81348143	FALSE	1	HDAC6	3267008	Infinity	0.02850018
790676	taxon:9606	2.32865921	4902.370002	0.00176198	171510	1902	mediator complex subunit 4	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED4			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED4	0.506473003	0.42943166	0.04566	229	4	0.012828413	FALSE	8.865546218	MED4	MED4	73.69868996	17.68406768	0	229	0	0.7785568	FALSE	0	MED4	1951122	Infinity	0.01826072
787413	taxon:9606	2.14825902	3969.611011	9.49E-04	179475	1902	nucleolin	gene	biological_process-&-1&-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0001525-&&-angiogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:NCL			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection	NCL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCL	0.529897588	0.46549322	0.14533546	229	4	0.054859377	FALSE	38.98969072	NCL	NCL	196.3964758	56.53499006	0	228	0	0.8086235	FALSE	1	NCL	2185866	Infinity	0.03787051
792563	taxon:9606	2.18528439	3365.712872	0.00220057	181811	1902	Cbl proto-oncogene	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0061024-&&-membrane organization-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0070997-&&-neuron death-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042594-&&-response to starvation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0090650-&&-cellular response to oxygen-glucose deprivation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033574-&&-response to testosterone-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0008584-&&-male gonad development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity|cellular_component-&-1&-GO:0016600-&&-flotillin complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion-%%-GO:0005634-&&-nucleus-%%-GO:0042629-&&-mast cell granule-%%-GO:0045121-&&-membrane raft-%%-GO:0030424-&&-axon-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:CBL			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	CBL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBL	0.516087516	0.45760634	0.08759892	229	4	0.020998085	FALSE	24.82352941	CBL	CBL	117.6740088	43.33908638	0	228	0	0.8024526	FALSE	1	CBL	2962578	Infinity	0.02377075
787127	taxon:9606	2.22845439	2341.436523	8.25E-04	180016	1902	interleukin enhancer binding factor 2	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:1904724-&&-tertiary granule lumen-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005730-&&-nucleolus-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016740-&&-transferase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ILF2				ILF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILF2	0.52486911	0.44874152	0.16615337	227	4	0.051834531	FALSE	44.54385965	ILF2	ILF2	171.6563877	60.39948682	0	227	0	0.7952576	FALSE	0	ILF2	1637826	Infinity	0.03667683
787400	taxon:9606	2.17472822	4150.379761	5.73E-04	179493	1902	heterogeneous nuclear ribonucleoprotein M	gene	biological_process-&-1&-GO:0010467-&&-gene expression-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042382-&&-paraspeckles-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding	G:9606:HNRNPM			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPM	0.532183145	0.45982757	0.17909633	227	4	0.055329174	FALSE	44.135	HNRNPM	HNRNPM	184.1762115	69.43179842	0	227	0	0.80421196	FALSE	0	HNRNPM	1502842	Infinity	0.03670311
793279	taxon:9606	2.20151253	3921.325488	0.0011437	180380	1902	H2A histone family member X	gene	biological_process-&-1&-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0090398-&&-cellular senescence-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0016032-&&-viral process-%%-GO:0006302-&&-double-strand break repair-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0000077-&&-DNA damage checkpoint|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005657-&&-replication fork-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0001741-&&-XY body-%%-GO:0005634-&&-nucleus-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:H2AFX			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	H2AFX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H2AFX	0.527458073	0.45423316	0.10626984	227	4	0.041478887	FALSE	29.70056497	H2AFX	H2AFX	159.5066667	45.23677291	0	226	0	0.79974791	FALSE	1	H2AFX	2145294	Infinity	0.03290466
788265	taxon:9606	2.18764771	1894.90497	9.87E-04	177975	1902	ribosomal protein S2	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0051347-&&-positive regulation of transferase activity-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS2			KEGG-&-1&-hsa03010-&&-Ribosome	RPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS2	0.526765189	0.45711199	0.25242871	226	4	0.059672602	FALSE	67.00543478	RPS2	RPS2	183.2212389	91.94722544	0	226	0	0.80205872	FALSE	0	RPS2	1812592	Infinity	0.03707341
788520	taxon:9606	2.18323617	3844.518875	0.00216205	177515	1902	Sp1 transcription factor	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0100057-&&-regulation of phenotypic switching by transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048511-&&-rhythmic process-%%-GO:0016032-&&-viral process-%%-GO:1904828-&&-positive regulation of hydrogen sulfide biosynthetic process-%%-GO:0032869-&&-cellular response to insulin stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding	G:9606:SP1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05016-&&-Huntington disease-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04915-&&-Estrogen signaling pathway	SP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP1	0.520441272	0.45803565	0.07971653	226	4	0.023968836	FALSE	23.65517241	SP1	SP1	123.5803571	37.42526102	0	225	0	0.80279397	FALSE	1	SP1	2947112	Infinity	0.02488131
792626	taxon:9606	2.16874114	1931.729005	5.34E-04	165314	1902	histone cluster 4 H4	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST4H4			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST4H4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST4H4	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST4H4	HIST4H4	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST4H4	2681022	Infinity	0.03645346
788907	taxon:9606	2.16874114	1931.729005	5.34E-04	176632	1902	histone cluster 1 H4 family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4E			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4E	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4E	HIST1H4E	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4E	2681022	Infinity	0.03645346
788908	taxon:9606	2.16874114	1931.729005	5.34E-04	176635	1902	histone cluster 1 H4 family member c	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4C			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4C	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4C	HIST1H4C	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4C	2681022	Infinity	0.03645346
788909	taxon:9606	2.16874114	1931.729005	5.34E-04	176634	1902	histone cluster 1 H4 family member h	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4H			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4H	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4H	HIST1H4H	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4H	2681022	Infinity	0.03645346
788910	taxon:9606	2.16874114	1931.729005	5.34E-04	176629	1902	histone cluster 2 H4 family member a	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H4A			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H4A	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST2H4A	HIST2H4A	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST2H4A	2681022	Infinity	0.03645346
788906	taxon:9606	2.16874114	1931.729005	5.34E-04	176633	1902	histone cluster 1 H4 family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4B			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4B	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4B	HIST1H4B	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4B	2681022	Infinity	0.03645346
788911	taxon:9606	2.16874114	1931.729005	5.34E-04	176631	1902	histone cluster 1 H4 family member l	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4L			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4L	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4L	HIST1H4L	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4L	2681022	Infinity	0.03645346
789032	taxon:9606	2.16874114	1931.729005	5.34E-04	176320	1902	histone cluster 1 H4 family member i	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4I			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4I	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4I	HIST1H4I	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4I	2681022	Infinity	0.03645346
789196	taxon:9606	2.16874114	1931.729005	5.34E-04	176024	1902	histone cluster 1 H4 family member a	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4A			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4A	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4A	HIST1H4A	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4A	2681022	Infinity	0.03645346
789199	taxon:9606	2.16874114	1931.729005	5.34E-04	176021	1902	histone cluster 1 H4 family member k	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4K			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4K	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4K	HIST1H4K	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4K	2681022	Infinity	0.03645346
789200	taxon:9606	2.16874114	1931.729005	5.34E-04	176020	1902	histone cluster 1 H4 family member j	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4J			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4J	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4J	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4J	HIST1H4J	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4J	2681022	Infinity	0.03645346
789201	taxon:9606	2.16874114	1931.729005	5.34E-04	176023	1902	histone cluster 1 H4 family member d	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4D			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4D	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4D	HIST1H4D	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4D	2681022	Infinity	0.03645346
789202	taxon:9606	2.16874114	1931.729005	5.34E-04	176022	1902	histone cluster 1 H4 family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4F			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4F	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST1H4F	HIST1H4F	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST1H4F	2681022	Infinity	0.03645346
789656	taxon:9606	2.14951946	4481.592707	0.00178426	174967	1902	receptor for activated C kinase 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0043473-&&-pigmentation-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:2000543-&&-positive regulation of gastrulation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:1903208-&&-negative regulation of hydrogen peroxide-induced neuron death-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0051343-&&-positive regulation of cyclic-nucleotide phosphodiesterase activity-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:1900102-&&-negative regulation of endoplasmic reticulum unfolded protein response-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0048511-&&-rhythmic process-%%-GO:0007369-&&-gastrulation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0006412-&&-translation-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0030822-&&-positive regulation of cAMP catabolic process-%%-GO:0051302-&&-regulation of cell division-%%-GO:0042998-&&-positive regulation of Golgi to plasma membrane protein transport-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0030425-&&-dendrite-%%-GO:0001891-&&-phagocytic cup-%%-GO:0030496-&&-midbody-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body-%%-GO:1990630-&&-IRE1-RACK1-PP2A complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0003723-&&-RNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0035591-&&-signaling adaptor activity-%%-GO:0008200-&&-ion channel inhibitor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0030292-&&-protein tyrosine kinase inhibitor activity	G:9606:RACK1			KEGG-&-1&-hsa05162-&&-Measles	RACK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RACK1	0.526592252	0.46522026	0.12471973	226	4	0.049484428	FALSE	35.38857143	RACK1	RACK1	186.2767857	47.21761375	0	225	0	0.80841342	FALSE	1	RACK1	3323436	Infinity	0.03599293
790439	taxon:9606	2.16874114	1931.729005	5.34E-04	156594	1902	histone cluster 2 H4 family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H4B			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H4B	0.527458073	0.46109699	0.12361849	226	4	0.045809608	FALSE	30.48888889	HIST2H4B	HIST2H4B	184.3495575	48.47647527	0	226	0	0.80520981	FALSE	0	HIST2H4B	2681022	Infinity	0.03645346
789861	taxon:9606	2.22089176	1765.140195	0.00172322	174492	1902	COP9 signalosome subunit 6	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0016032-&&-viral process-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS6				COPS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS6	0.516586151	0.45026958	0.0894437	225	4	0.033431549	FALSE	28.96946565	COPS6	COPS6	128.4170404	36.96912128	0	224	0	0.79651804	FALSE	1	COPS6	2442586	Infinity	0.02713711
790565	taxon:9606	2.17787931	3594.794825	8.11E-04	172127	1902	poly(A) binding protein cytoplasmic 1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:2000623-&&-negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0006413-&&-translational initiation-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0008143-&&-poly(A) binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008494-&&-translation activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding	G:9606:PABPC1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa03018-&&-RNA degradation	PABPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPC1	0.529372937	0.45916227	0.16721514	223	4	0.055444714	FALSE	43.09574468	PABPC1	PABPC1	197.719457	62.0458813	0	222	0	0.80368678	FALSE	1	PABPC1	1850518	Infinity	0.03949559
792684	taxon:9606	2.18969592	4253.514394	0.00129576	181561	1902	damage specific DNA binding protein 1	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0046726-&&-positive regulation by virus of viral protein levels in host cell-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0051702-&&-interaction with symbiont-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:DDB1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa05161-&&-Hepatitis B	DDB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDB1	0.522986632	0.45668442	0.08502674	223	4	0.034840442	FALSE	23.34415584	DDB1	DDB1	160.8687783	36.87637807	0	222	0	0.80171735	FALSE	1	DDB1	2581868	Infinity	0.03262213
788868	taxon:9606	2.10950055	4719.285436	0.00185085	176729	1902	vimentin	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070307-&&-lens fiber cell development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0014002-&&-astrocyte development-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005882-&&-intermediate filament-%%-GO:0005777-&&-peroxisome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0005212-&&-structural constituent of eye lens-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:1990254-&&-keratin filament binding-%%-GO:0042802-&&-identical protein binding	G:9606:VIM	VIM	TRUE	KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05206-&&-MicroRNAs in cancer	VIM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VIM	0.523669605	0.47404586	0.06351296	223	4	0.031982005	FALSE	19.26973684	VIM	VIM	157.081448	29.29997498	0	222	0	0.81508324	FALSE	1	VIM	3189184	Infinity	0.02891978
788625	taxon:9606	2.23333859	3543.028562	0.00145724	177291	1902	telomeric repeat binding factor 1	gene	biological_process-&-1&-GO:0031627-&&-telomeric loop formation-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0051301-&&-cell division-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0090656-&&-t-circle formation-%%-GO:1905778-&&-negative regulation of exonuclease activity-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0016233-&&-telomere capping-%%-GO:1904850-&&-negative regulation of establishment of protein localization to telomere-%%-GO:0032214-&&-negative regulation of telomere maintenance via semi-conservative replication-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1904792-&&-positive regulation of shelterin complex assembly-%%-GO:1905839-&&-negative regulation of telomeric D-loop disassembly-%%-GO:1904914-&&-negative regulation of establishment of macromolecular complex localization to telomere-%%-GO:0042493-&&-response to drug-%%-GO:0045141-&&-meiotic telomere clustering-%%-GO:1904911-&&-negative regulation of establishment of RNA localization to telomere-%%-GO:0000723-&&-telomere maintenance-%%-GO:0051974-&&-negative regulation of telomerase activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0070187-&&-shelterin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0001650-&&-fibrillar center-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003720-&&-telomerase activity-%%-GO:0071532-&&-ankyrin repeat binding-%%-GO:0008301-&&-DNA binding, bending	G:9606:TERF1				TERF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERF1	0.515755627	0.44776014	0.04425073	222	4	0.022161752	FALSE	14.02238806	TERF1	TERF1	102.1590909	22.59378492	0	221	0	0.79444357	FALSE	1	TERF1	2074636	Infinity	0.02193277
787583	taxon:9606	2.2371199	2695.346064	7.75E-04	179146	1902	neural precursor cell expressed, developmentally down-regulated 8	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0045116-&&-protein neddylation-%%-GO:0008104-&&-protein localization-%%-GO:0006508-&&-proteolysis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:NEDD8				NEDD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD8	0.523498695	0.44700331	0.12224038	221	4	0.042150088	FALSE	32.96987952	NEDD8	NEDD8	146.6118722	46.70060702	0	220	0	0.79381335	FALSE	1	NEDD8	1519266	Infinity	0.03163731
788275	taxon:9606	2.21143847	1694.625129	4.75E-04	177961	1902	ribosomal protein S8	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS8			KEGG-&-1&-hsa03010-&&-Ribosome	RPS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS8	0.526938239	0.45219436	0.28062526	221	4	0.061188217	FALSE	70.36263736	RPS8	RPS8	192.4298643	94.76127347	0	221	0	0.79809359	FALSE	0	RPS8	1243238	Infinity	0.0401481
787218	taxon:9606	2.26280132	3098.775859	0.00127021	179841	1902	mutated in colorectal cancers	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010633-&&-negative regulation of epithelial cell migration|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:MCC				MCC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCC	0.513115803	0.44193009	0.03330401	219	4	0.019607324	FALSE	8.936507937	MCC	MCC	91.42922374	14.20085166	0	219	0	0.78953311	FALSE	0	MCC	1778078	Infinity	0.02044122
792424	taxon:9606	2.1807153	2620.304226	0.003029	182047	1902	casein kinase 2 beta	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0006457-&&-protein folding-%%-GO:0097421-&&-liver regeneration-%%-GO:0007165-&&-signal transduction-%%-GO:0033574-&&-response to testosterone-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0033211-&&-adiponectin-activated signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032927-&&-positive regulation of activin receptor signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0051101-&&-regulation of DNA binding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005929-&&-cilium-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000785-&&-chromatin-%%-GO:0005956-&&-protein kinase CK2 complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0031519-&&-PcG protein complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019887-&&-protein kinase regulator activity	G:9606:CSNK2B			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04520-&&-Adherens junction-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2B	0.515589842	0.45856513	0.0499232	219	4	0.023486605	FALSE	16.4173913	CSNK2B	CSNK2B	123.4654378	21.46714319	0	218	0	0.80321412	FALSE	1	CSNK2B	3671436	Infinity	0.02481233
793215	taxon:9606	2.10398614	3239.435724	0.00126857	180519	1902	heat shock protein family A (Hsp70) member 1A	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0070434-&&-positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0042026-&&-protein refolding-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0090063-&&-positive regulation of microtubule nucleation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0046034-&&-ATP metabolic process-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:1901029-&&-negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0034605-&&-cellular response to heat-%%-GO:1902380-&&-positive regulation of endoribonuclease activity-%%-GO:0010941-&&-regulation of cell death-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:1904722-&&-positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0097201-&&-negative regulation of transcription from RNA polymerase II promoter in response to stress|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016234-&&-inclusion body-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0044183-&&-protein binding involved in protein folding	G:9606:HSPA1A	HSPA1A	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05020-&&-Prion diseases-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA1A	0.525040917	0.4752883	0.09635122	219	4	0.038763639	FALSE	24.6746988	HSPA1A	HSPA1A	179.8127854	37.51224858	0	219	0	0.81600231	FALSE	0	HSPA1A	2983846	Infinity	0.03285969
793216	taxon:9606	2.10398614	3239.435724	0.00126857	180518	1902	heat shock protein family A (Hsp70) member 1B	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0070434-&&-positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0042026-&&-protein refolding-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0090063-&&-positive regulation of microtubule nucleation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0046034-&&-ATP metabolic process-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0034605-&&-cellular response to heat-%%-GO:0010941-&&-regulation of cell death|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0016234-&&-inclusion body-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:HSPA1B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA1B	0.525040917	0.4752883	0.09635122	219	4	0.038763639	FALSE	24.6746988	HSPA1B	HSPA1B	179.8127854	37.51224858	0	219	0	0.81600231	FALSE	0	HSPA1B	2983846	Infinity	0.03285969
792699	taxon:9606	2.17551599	3369.364007	5.86E-04	181545	1902	DExH-box helicase 9	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006396-&&-RNA processing-%%-GO:0048511-&&-rhythmic process-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule|cellular_component-&-1&-GO:0097165-&&-nuclear stress granule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity	G:9606:DHX9				DHX9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX9	0.528326746	0.45966107	0.16326443	218	4	0.051564865	FALSE	40.34054054	DHX9	DHX9	194.7685185	60.44186676	0	217	0	0.80408067	FALSE	1	DHX9	1486368	Infinity	0.03873678
788724	taxon:9606	2.18339373	3608.683883	0.00267797	177119	1902	TNF receptor associated factor 2	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:1903721-&&-positive regulation of I-kappaB phosphorylation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0030163-&&-protein catabolic process-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0071732-&&-cellular response to nitric oxide|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:1990597-&&-AIP1-IRE1 complex-%%-GO:0045121-&&-membrane raft-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:1990604-&&-IRE1-TRAF2-ASK1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097057-&&-TRAF2-GSTP1 complex-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005174-&&-CD40 receptor binding-%%-GO:0046625-&&-sphingolipid binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding	G:9606:TRAF2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	TRAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF2	0.515921518	0.4580026	0.06533161	218	4	0.019495452	FALSE	20.03937008	TRAF2	TRAF2	105.6111111	31.98232763	0	217	0	0.80276771	FALSE	1	TRAF2	3015152	Infinity	0.02123411
787732	taxon:9606	2.20434851	3131.650053	0.00145375	178862	1902	RNA polymerase II subunit A	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0001172-&&-transcription, RNA-templated-%%-GO:0010467-&&-gene expression-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0000974-&&-Prp19 complex-%%-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003968-&&-RNA-directed 5'-3' RNA polymerase activity	G:9606:POLR2A			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2A	0.518087855	0.45364877	0.08611171	217	4	0.029108876	FALSE	22.21052632	POLR2A	POLR2A	140.1674419	33.13794955	0	216	0	0.79927525	FALSE	1	POLR2A	2389648	Infinity	0.02888284
788794	taxon:9606	2.21632267	3416.993726	0.0029681	176882	1902	BCL2 associated athanogene 6	gene	biological_process-&-1&-GO:0007420-&&-brain development-%%-GO:0050821-&&-protein stabilization-%%-GO:0009790-&&-embryo development-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0071816-&&-tail-anchored membrane protein insertion into ER membrane-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:1904294-&&-positive regulation of ERAD pathway-%%-GO:0007130-&&-synaptonemal complex assembly-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030324-&&-lung development-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1904379-&&-protein localization to cytosolic proteasome complex involved in ERAD pathway-%%-GO:0006810-&&-transport-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:0002429-&&-immune response-activating cell surface receptor signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0001822-&&-kidney development-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:1904378-&&-maintenance of unfolded protein involved in ERAD pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0071818-&&-BAT3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0015643-&&-toxic substance binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0031593-&&-polyubiquitin binding	G:9606:BAG6				BAG6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG6	0.513444302	0.45119784	0.03403608	217	4	0.016545888	FALSE	11.74774775	BAG6	BAG6	97.02790698	17.07637892	0	216	0	0.79727955	FALSE	1	BAG6	3295106	Infinity	0.02039409
789771	taxon:9606	2.1573972	4715.107833	0.00163006	174720	1902	tripartite motif containing 28	gene	biological_process-&-1&-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090309-&&-positive regulation of methylation-dependent chromatin silencing-%%-GO:0045869-&&-negative regulation of single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0051259-&&-protein oligomerization-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0060669-&&-embryonic placenta morphogenesis-%%-GO:0007566-&&-embryo implantation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0060028-&&-convergent extension involved in axis elongation-%%-GO:1901536-&&-negative regulation of DNA demethylation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045087-&&-innate immune response-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:2000653-&&-regulation of genetic imprinting|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0070087-&&-chromo shadow domain binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0035851-&&-Krueppel-associated box domain binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:TRIM28				TRIM28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM28	0.525384867	0.46352151	0.10113641	216	4	0.042613257	FALSE	26.72352941	TRIM28	TRIM28	195.1401869	39.4707054	0	215	0	0.80710047	FALSE	1	TRIM28	2912760	Infinity	0.03795491
789068	taxon:9606	2.13407909	3612.780086	0.00170098	176248	1902	IQ motif containing GTPase activating protein 1	gene	biological_process-&-1&-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:1903829-&&-positive regulation of cellular protein localization-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0072015-&&-glomerular visceral epithelial cell development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1990776-&&-response to angiotensin-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1900086-&&-positive regulation of peptidyl-tyrosine autophosphorylation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007165-&&-signal transduction-%%-GO:1990138-&&-neuron projection extension-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0035305-&&-negative regulation of dephosphorylation-%%-GO:1900006-&&-positive regulation of dendrite development|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005884-&&-actin filament-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0036057-&&-slit diaphragm-%%-GO:0001726-&&-ruffle-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043234-&&-protein complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft-%%-GO:0043005-&&-neuron projection-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:IQGAP1			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction	IQGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQGAP1	0.521965506	0.46858619	0.10758531	215	4	0.030289413	FALSE	25.89864865	IQGAP1	IQGAP1	155.9116279	41.31084064	0	215	0	0.81098682	FALSE	0	IQGAP1	2676824	Infinity	0.02950548
790172	taxon:9606	2.2256184	3295.346518	0.0026399	173719	1902	lysine demethylase 1A	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0055001-&&-muscle cell development-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0060992-&&-response to fungicide-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0046886-&&-positive regulation of hormone biosynthetic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0010725-&&-regulation of primitive erythrocyte differentiation-%%-GO:0033184-&&-positive regulation of histone ubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1990138-&&-neuron projection extension-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0007596-&&-blood coagulation-%%-GO:0021983-&&-pituitary gland development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045654-&&-positive regulation of megakaryocyte differentiation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0034720-&&-histone H3-K4 demethylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046098-&&-guanine metabolic process-%%-GO:0006482-&&-protein demethylation-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0042551-&&-neuron maturation-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0071320-&&-cellular response to cAMP|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:1990391-&&-DNA repair complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0032451-&&-demethylase activity-%%-GO:0032453-&&-histone demethylase activity (H3-K4 specific)-%%-GO:0034648-&&-histone demethylase activity (H3-dimethyl-K4 specific)-%%-GO:0043426-&&-MRF binding-%%-GO:0061752-&&-telomeric repeat-containing RNA binding-%%-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0002039-&&-p53 binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003682-&&-chromatin binding	G:9606:KDM1A			KEGG-&-1&-hsa04714-&&-Thermogenesis	KDM1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM1A	0.515921518	0.44931332	0.06758792	215	4	0.023699423	FALSE	21.51260504	KDM1A	KDM1A	127.4694836	28.89497254	0	214	0	0.79573027	FALSE	1	KDM1A	3460576	Infinity	0.02705162
788045	taxon:9606	2.20340318	1507.118305	4.50E-04	178309	1902	ribosomal protein L6	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL6			KEGG-&-1&-hsa03010-&&-Ribosome	RPL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL6	0.524525834	0.4538434	0.29827564	214	4	0.06099109	FALSE	71.28571429	RPL6	RPL6	193.5560748	97.37104311	0	214	0	0.7994328	FALSE	0	RPL6	1124898	Infinity	0.03989832
788266	taxon:9606	2.17693398	2997.905748	3.55E-04	177974	1902	ribosomal protein S3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006412-&&-translation-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0051225-&&-spindle assembly-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0061481-&&-response to TNF agonist-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0045738-&&-negative regulation of DNA repair-%%-GO:0007059-&&-chromosome segregation-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1902546-&&-positive regulation of DNA N-glycosylase activity-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1905053-&&-positive regulation of base-excision repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006413-&&-translational initiation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0032079-&&-positive regulation of endodeoxyribonuclease activity-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006979-&&-response to oxidative stress-%%-GO:2001272-&&-positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0019083-&&-viral transcription-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005840-&&-ribosome-%%-GO:0005844-&&-polysome-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0032358-&&-oxidized pyrimidine DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004520-&&-endodeoxyribonuclease activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019900-&&-kinase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0051536-&&-iron-sulfur cluster binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0044390-&&-ubiquitin-like protein conjugating enzyme binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0019104-&&-DNA N-glycosylase activity-%%-GO:0070181-&&-small ribosomal subunit rRNA binding-%%-GO:0032183-&&-SUMO binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0015631-&&-tubulin binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0097100-&&-supercoiled DNA binding	G:9606:RPS3			KEGG-&-1&-hsa03010-&&-Ribosome	RPS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS3	0.530598743	0.45936166	0.29305428	214	4	0.062804364	FALSE	64.96551724	RPS3	RPS3	203.228972	98.51020598	0	214	0	0.80384434	FALSE	0	RPS3	1214694	Infinity	0.04051614
792694	taxon:9606	2.14053884	3241.469316	8.97E-04	181549	1902	DEAD-box helicase 5	gene	biological_process-&-1&-GO:0045069-&&-regulation of viral genome replication-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:2001014-&&-regulation of skeletal muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009299-&&-mRNA transcription-%%-GO:0048511-&&-rhythmic process-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0016049-&&-cell growth-%%-GO:0045667-&&-regulation of osteoblast differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0003724-&&-RNA helicase activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0036002-&&-pre-mRNA binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DDX5			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa03040-&&-Spliceosome	DDX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX5	0.526765189	0.46717209	0.14249307	214	4	0.047777679	FALSE	36.32758621	DDX5	DDX5	199.6462264	51.27525236	0	213	0	0.80991019	FALSE	1	DDX5	2018628	Infinity	0.03806141
788800	taxon:9606	2.13770285	2894.192951	0.00121386	176847	1902	tubulin gamma 1	gene	biological_process-&-1&-GO:0007020-&&-microtubule nucleation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0000212-&&-meiotic spindle organization|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0097730-&&-non-motile cilium-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0031252-&&-cell leading edge-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0055037-&&-recycling endosome-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005827-&&-polar microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding	G:9606:TUBG1			KEGG-&-1&-hsa05165-&&-Human papillomavirus infection	TUBG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBG1	0.524011761	0.46779186	0.11629259	214	4	0.042049155	FALSE	31.72955975	TUBG1	TUBG1	165.004717	42.44686537	0	213	0	0.81038286	FALSE	1	TUBG1	2100290	Infinity	0.03133814
789691	taxon:9606	2.17378289	2446.148104	0.00141089	174884	1902	synaptotagmin binding cytoplasmic RNA interacting protein	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0006396-&&-RNA processing-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0016032-&&-viral process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0097452-&&-GAIT complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008143-&&-poly(A) binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SYNCRIP				SYNCRIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNCRIP	0.522645813	0.46002754	0.11759028	214	4	0.041802276	FALSE	32.44295302	SYNCRIP	SYNCRIP	170.7570094	42.09126784	0	214	0	0.80436952	FALSE	0	SYNCRIP	2381128	Infinity	0.0339247
787869	taxon:9606	2.18103041	4502.584968	0.0015104	178669	1902	proteasome subunit alpha 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0052548-&&-regulation of endopeptidase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005839-&&-proteasome core complex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA3			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA3	0.523498695	0.45849888	0.11293162	213	4	0.030212559	FALSE	30.15853659	PSMA3	PSMA3	136.7251185	52.8534402	0	212	0	0.8031616	FALSE	1	PSMA3	2089650	Infinity	0.02743621
788470	taxon:9606	2.19946431	2679.039257	0.00113896	177582	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0003407-&&-neural retina development-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0006325-&&-chromatin organization-%%-GO:1902661-&&-positive regulation of glucose mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007399-&&-nervous system development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007070-&&-negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0071564-&&-npBAF complex-%%-GO:0071565-&&-nBAF complex-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0004386-&&-helicase activity-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0030957-&&-Tat protein binding	G:9606:SMARCA4			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA4	0.520610191	0.45465616	0.12872941	213	4	0.035091482	FALSE	33.68666667	SMARCA4	SMARCA4	165.2227488	48.60750932	0	212	0	0.80008928	FALSE	1	SMARCA4	2268096	Infinity	0.03382247
793177	taxon:9606	2.22861194	2715.753723	0.00110475	180582	1902	stratifin	gene	biological_process-&-1&-GO:0045606-&&-positive regulation of epidermal cell differentiation-%%-GO:0061024-&&-membrane organization-%%-GO:0031424-&&-keratinization-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0003334-&&-keratinocyte development-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0010482-&&-regulation of epidermal cell division|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008426-&&-protein kinase C inhibitor activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding	G:9606:SFN			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption	SFN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFN	0.514927769	0.44870979	0.07691957	212	4	0.031373326	FALSE	22.86363636	SFN	SFN	124.8428571	28.93306241	0	211	0	0.79523134	FALSE	1	SFN	1733098	Infinity	0.02654334
790074	taxon:9606	2.29383961	2363.667275	7.98E-04	173937	1902	centrosomal protein 250	gene	biological_process-&-1&-GO:0030997-&&-regulation of centriole-centriole cohesion-%%-GO:0008104-&&-protein localization-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:1904781-&&-positive regulation of protein localization to centrosome|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0005814-&&-centriole-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CEP250				CEP250	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP250	0.517252499	0.43595027	0.10600912	212	4	0.043257371	FALSE	27.89937107	CEP250	CEP250	137.1462264	34.29675657	0	212	0	0.78436007	FALSE	0	CEP250	1542388	Infinity	0.03201753
790602	taxon:9606	2.33385852	1634.070716	9.20E-04	155470	1902	POU class 5 homeobox 1 pseudogene 4	gene		G:9606:POU5F1P4				POU5F1P4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU5F1P4	0.507273877	0.42847499	0.05148141	211	4	0.019431679	FALSE	14.48695652	POU5F1P4	POU5F1P4	91.54066986	19.77247446	0	210	0	0.77769025	FALSE	1	POU5F1P4	1851794	Infinity	0.0225859
787575	taxon:9606	2.21569245	2553.86947	0.00234499	179149	1902	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0031175-&&-neuron projection development-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0046824-&&-positive regulation of nucleocytoplasmic transport-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0050807-&&-regulation of synapse organization-%%-GO:0051592-&&-response to calcium ion-%%-GO:0044111-&&-development involved in symbiotic interaction-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010768-&&-negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0007041-&&-lysosomal transport-%%-GO:0002250-&&-adaptive immune response-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0010766-&&-negative regulation of sodium ion transport-%%-GO:0019089-&&-transmission of virus-%%-GO:0031623-&&-receptor internalization-%%-GO:0042110-&&-T cell activation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043197-&&-dendritic spine-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000785-&&-chromatin-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0050816-&&-phosphothreonine binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019871-&&-sodium channel inhibitor activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031698-&&-beta-2 adrenergic receptor binding-%%-GO:0050815-&&-phosphoserine binding	G:9606:NEDD4			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04530-&&-Tight junction	NEDD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD4	0.511316544	0.45132618	0.04016378	211	4	0.01759894	FALSE	13.80909091	NEDD4	NEDD4	102.0382775	19.00677568	0	210	0	0.79738459	FALSE	1	NEDD4	2743946	Infinity	0.02140503
787755	taxon:9606	2.33385852	1634.070716	9.20E-04	178833	1902	POU class 5 homeobox 1	gene	biological_process-&-1&-GO:0001714-&&-endodermal cell fate specification-%%-GO:0060965-&&-negative regulation of gene silencing by miRNA-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0009786-&&-regulation of asymmetric cell division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0009611-&&-response to wounding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0001824-&&-blastocyst development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:POU5F1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	POU5F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU5F1	0.507273877	0.42847499	0.05148141	211	4	0.019431679	FALSE	14.48695652	POU5F1	POU5F1	91.54066986	19.77247446	0	210	0	0.77769025	FALSE	1	POU5F1	1851794	Infinity	0.0225859
792844	taxon:9606	2.22325508	2433.37389	0.00261432	181273	1902	erb-b2 receptor tyrosine kinase 2	gene	biological_process-&-1&-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0007507-&&-heart development-%%-GO:0033088-&&-negative regulation of immature T cell proliferation in thymus-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0042060-&&-wound healing-%%-GO:0042552-&&-myelination-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001042-&&-RNA polymerase I core binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:ERBB2	ERBB2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04530-&&-Tight junction-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05226-&&-Gastric cancer	ERBB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBB2	0.506473003	0.44979094	0.05309165	211	4	0.013350928	FALSE	16.64646465	ERBB2	ERBB2	89.86602871	24.23164233	0	210	0	0.79612415	FALSE	1	ERBB2	2729274	Infinity	0.01902426
790431	taxon:9606	2.33385852	1634.070716	9.20E-04	156622	1902	POU class 5 homeobox 1 pseudogene 3	gene		G:9606:POU5F1P3				POU5F1P3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU5F1P3	0.507273877	0.42847499	0.05148141	211	4	0.019431679	FALSE	14.48695652	POU5F1P3	POU5F1P3	91.54066986	19.77247446	0	210	0	0.77769025	FALSE	1	POU5F1P3	1851794	Infinity	0.0225859
788895	taxon:9606	2.16905625	3275.729468	0.00104625	176657	1902	X-ray repair cross complementing 5	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0006310-&&-DNA recombination-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0008283-&&-cell proliferation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071475-&&-cellular hyperosmotic salinity response-%%-GO:0060218-&&-hematopoietic stem cell differentiation-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:1904430-&&-negative regulation of t-circle formation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0007420-&&-brain development-%%-GO:0006302-&&-double-strand break repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0043564-&&-Ku70:Ku80 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0070419-&&-nonhomologous end joining complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0051575-&&-5'-deoxyribose-5-phosphate lyase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044877-&&-macromolecular complex binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:XRCC5			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining	XRCC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRCC5	0.523327896	0.46103	0.1104608	210	4	0.039464075	FALSE	27.94339623	XRCC5	XRCC5	182.5769231	40.67292967	0	209	0	0.80515729	FALSE	1	XRCC5	2295506	Infinity	0.03600743
787132	taxon:9606	2.20387585	2742.292595	0.0013877	180014	1902	integrin linked kinase	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0070527-&&-platelet aggregation-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0034329-&&-cell junction assembly-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0021675-&&-nerve development-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0032288-&&-myelin assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0010761-&&-fibroblast migration-%%-GO:0008283-&&-cell proliferation-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007569-&&-cell aging-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0097435-&&-supramolecular fiber organization|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043034-&&-costamere-%%-GO:0043195-&&-terminal bouton-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0001725-&&-stress fiber-%%-GO:0030017-&&-sarcomere|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004871-&&-signal transducer activity	G:9606:ILK	ILK	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05213-&&-Endometrial cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa03320-&&-PPAR signaling pathway	ILK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILK	0.517419355	0.45374607	0.05121711	209	4	0.024405099	FALSE	15.72868217	ILK	ILK	115.3719807	22.00236172	0	208	0	0.79935403	FALSE	1	ILK	1944432	Infinity	0.02380069
789079	taxon:9606	2.21301402	2939.516068	0.00112861	176234	1902	histone deacetylase 3	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006476-&&-protein deacetylation-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051225-&&-spindle assembly-%%-GO:0006325-&&-chromatin organization-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0010832-&&-negative regulation of myotube differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0019899-&&-enzyme binding	G:9606:HDAC3	HDAC3	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC3	0.518590365	0.45187242	0.12063224	209	4	0.03100536	FALSE	30.55782313	HDAC3	HDAC3	148.9661836	43.77627295	0	208	0	0.797831	FALSE	1	HDAC3	2129850	Infinity	0.03103462
790365	taxon:9606	2.20497873	2222.802654	8.25E-04	173214	1902	serine/arginine repetitive matrix 2	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:SRRM2				SRRM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRRM2	0.524183007	0.45351911	0.15646853	209	4	0.044944759	FALSE	37.8253012	SRRM2	SRRM2	176.6507177	53.59584566	0	209	0	0.79917021	FALSE	0	SRRM2	1626916	Infinity	0.0364434
787544	taxon:9606	2.16448716	2322.817135	0.00174837	179218	1902	protein phosphatase 2 scaffold subunit Aalpha	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0051306-&&-mitotic sister chromatid separation-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0051754-&&-meiotic sister chromatid cohesion, centromeric-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0008380-&&-RNA splicing-%%-GO:0010033-&&-response to organic substance-%%-GO:0007059-&&-chromosome segregation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051232-&&-meiotic spindle elongation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0019932-&&-second-messenger-mediated signaling-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006915-&&-apoptotic process-%%-GO:0007143-&&-female meiotic division-%%-GO:0040008-&&-regulation of growth-%%-GO:1903538-&&-regulation of meiotic cell cycle process involved in oocyte maturation-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005634-&&-nucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003823-&&-antigen binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019888-&&-protein phosphatase regulator activity	G:9606:PPP2R1A			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R1A	0.517419355	0.4620032	0.07738759	208	4	0.027994161	FALSE	19.79831933	PPP2R1A	PPP2R1A	146.9615385	25.7285316	0	208	0	0.80591881	FALSE	0	PPP2R1A	2654446	Infinity	0.02882635
787716	taxon:9606	2.15188278	4023.914889	0.00157552	178894	1902	promyelocytic leukemia	gene	biological_process-&-1&-GO:0030155-&&-regulation of cell adhesion-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0010332-&&-response to gamma radiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0090398-&&-cellular senescence-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0010522-&&-regulation of calcium ion transport into cytosol-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030578-&&-PML body organization-%%-GO:0034097-&&-response to cytokine-%%-GO:0045087-&&-innate immune response-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0010761-&&-fibroblast migration-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0050713-&&-negative regulation of interleukin-1 beta secretion-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0009411-&&-response to UV-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:2000779-&&-regulation of double-strand break repair-%%-GO:0045165-&&-cell fate commitment-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process-%%-GO:0051607-&&-defense response to virus-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0042406-&&-extrinsic component of endoplasmic reticulum membrane-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032183-&&-SUMO binding	G:9606:PML			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05164-&&-Influenza A	PML	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PML	0.52094836	0.46470933	0.08493544	207	4	0.025107678	FALSE	22.35172414	PML	PML	143.4243902	35.71809944	0	206	0	0.80801954	FALSE	1	PML	2503876	Infinity	0.02762223
793362	taxon:9606	2.16291161	2410.366132	0.00164448	180239	1902	heterogeneous nuclear ribonucleoprotein D	gene	biological_process-&-1&-GO:0097167-&&-circadian regulation of translation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0021549-&&-cerebellum development-%%-GO:1901355-&&-response to rapamycin-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905663-&&-positive regulation of telomerase RNA reverse transcriptase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0001889-&&-liver development-%%-GO:1990828-&&-hepatocyte dedifferentiation-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0010467-&&-gene expression-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1904586-&&-cellular response to putrescine-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0006396-&&-RNA processing-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:1904383-&&-response to sodium phosphate|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003680-&&-AT DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:HNRNPD				HNRNPD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPD	0.521795706	0.46233974	0.11487327	207	4	0.038605638	FALSE	31.83333333	HNRNPD	HNRNPD	167.1804878	42.29032531	0	206	0	0.8061814	FALSE	1	HNRNPD	2460094	Infinity	0.03272533
789699	taxon:9606	2.16889869	4355.398967	0.00167604	174861	1902	lysine acetyltransferase 5	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0006302-&&-double-strand break repair-%%-GO:1901985-&&-positive regulation of protein acetylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0040008-&&-regulation of growth-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0016573-&&-histone acetylation-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0000732-&&-strand displacement-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032703-&&-negative regulation of interleukin-2 production|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0032777-&&-Piccolo NuA4 histone acetyltransferase complex-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000812-&&-Swr1 complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0050681-&&-androgen receptor binding	G:9606:KAT5			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	KAT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT5	0.519766688	0.46106349	0.10059886	206	4	0.030355161	FALSE	26.93661972	KAT5	KAT5	155.8970588	36.50233821	0	205	0	0.80518355	FALSE	1	KAT5	2789656	Infinity	0.03070582
793222	taxon:9606	2.09752639	3242.08339	0.00151093	180510	1902	heat shock protein family A (Hsp70) member 9	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:1902037-&&-negative regulation of hematopoietic stem cell differentiation-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:HSPA9			KEGG-&-1&-hsa05152-&&-Tuberculosis-%%-hsa03018-&&-RNA degradation	HSPA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA9	0.526074123	0.47675205	0.10301291	205	4	0.039950497	FALSE	24.35582822	HSPA9	HSPA9	196.1853659	35.81424477	0	205	0	0.81707893	FALSE	0	HSPA9	2900026	Infinity	0.03550778
790018	taxon:9606	2.14022373	3840.580221	0.00107016	174088	1902	RuvB like AAA ATPase 2	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006457-&&-protein folding-%%-GO:0071733-&&-transcriptional activation by promoter-enhancer looping-%%-GO:0071899-&&-negative regulation of estrogen receptor binding-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006310-&&-DNA recombination-%%-GO:0040008-&&-regulation of growth-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0034644-&&-cellular response to UV-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071169-&&-establishment of protein localization to chromatin-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0097255-&&-R2TP complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000812-&&-Swr1 complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005829-&&-cytosol-%%-GO:0031011-&&-Ino80 complex-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0043531-&&-ADP binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043141-&&-ATP-dependent 5'-3' DNA helicase activity	G:9606:RUVBL2				RUVBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUVBL2	0.523327896	0.46724087	0.10510657	205	4	0.036899805	FALSE	25.57792208	RUVBL2	RUVBL2	184.3349754	36.68927465	0	204	0	0.80996271	FALSE	1	RUVBL2	2297982	Infinity	0.03504467
787832	taxon:9606	2.1573972	2230.446059	0.00329437	178737	1902	mitogen-activated protein kinase 8	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0031063-&&-regulation of histone deacetylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0048666-&&-neuron development-%%-GO:0007258-&&-JUN phosphorylation-%%-GO:0007254-&&-JNK cascade-%%-GO:0031281-&&-positive regulation of cyclase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009411-&&-response to UV-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0048511-&&-rhythmic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0090045-&&-positive regulation of deacetylase activity-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004705-&&-JUN kinase activity-%%-GO:0035033-&&-histone deacetylase regulator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005524-&&-ATP binding	G:9606:MAPK8	MAPK8	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK8	0.510178117	0.46352151	0.05797744	204	4	0.016924469	FALSE	17.79816514	MAPK8	MAPK8	111.7623762	23.61680567	0	203	0	0.80710047	FALSE	1	MAPK8	3456186	Infinity	0.02170483
788162	taxon:9606	2.2851741	2225.542402	0.00125321	178140	1902	RAD21 cohesin complex component	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045876-&&-positive regulation of sister chromatid cohesion-%%-GO:0006915-&&-apoptotic process-%%-GO:0006302-&&-double-strand break repair-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0006310-&&-DNA recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0000798-&&-nuclear cohesin complex-%%-GO:0000785-&&-chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008278-&&-cohesin complex-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:RAD21			KEGG-&-1&-hsa04110-&&-Cell cycle	RAD21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD21	0.515424165	0.43760342	0.10509031	204	4	0.041009966	FALSE	26.70666667	RAD21	RAD21	152.3480392	33.82298805	0	204	0	0.78580432	FALSE	0	RAD21	2234592	Infinity	0.03506883
793089	taxon:9606	2.08003781	2706.375179	0.00200382	180754	1902	glyceraldehyde-3-phosphate dehydrogenase	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0050821-&&-protein stabilization-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0035606-&&-peptidyl-cysteine S-trans-nitrosylation-%%-GO:0051402-&&-neuron apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0097452-&&-GAIT complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004365-&&-glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0051287-&&-NAD binding-%%-GO:0050661-&&-NADP binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035605-&&-peptidyl-cysteine S-nitrosylase activity	G:9606:GAPDH	GAPDH	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	GAPDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAPDH	0.522816167	0.48076049	0.10896015	204	4	0.037304297	FALSE	28.96551724	GAPDH	GAPDH	192.7574257	39.0542021	0	203	0	0.8199937	FALSE	1	GAPDH	3237558	Infinity	0.03418291
789031	taxon:9606	2.28879786	1804.281436	8.71E-04	176324	1902	histone cluster 3 H3	gene	biological_process-&-1&-GO:0016233-&&-telomere capping-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0032460-&&-negative regulation of protein oligomerization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST3H3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST3H3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST3H3	0.513773222	0.43691058	0.11812226	204	4	0.029061206	FALSE	29.64393939	HIST3H3	HIST3H3	129.0247525	39.69590231	0	203	0	0.78520036	FALSE	1	HIST3H3	1647276	Infinity	0.02976007
787437	taxon:9606	2.45879943	840.1999288	0.0019785	163058	1902	transmembrane protein 17	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:1905515-&&-non-motile cilium assembly|cellular_component-&-1&-GO:0035869-&&-ciliary transition zone-%%-GO:0016021-&&-integral component of membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0036038-&&-MKS complex	G:9606:TMEM17				TMEM17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM17	0.440780434	0.40670255	0.01339835	202	4	0.00450302	FALSE	4.173076923	TMEM17	TMEM17	44.86138614	4.713522158	0	202	0	0.75686676	FALSE	0	TMEM17	1912852	Infinity	0.01393061
787681	taxon:9606	2.18812037	5883.765817	0.00170573	178960	1902	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	gene	biological_process-&-1&-GO:0050808-&&-synapse organization-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0050821-&&-protein stabilization-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060393-&&-regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0007049-&&-cell cycle-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0030182-&&-neuron differentiation-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0032794-&&-GTPase activating protein binding-%%-GO:0050816-&&-phosphothreonine binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0050815-&&-phosphoserine binding-%%-GO:0003774-&&-motor activity-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:PIN1			KEGG-&-1&-hsa04622-&&-RIG-I-like receptor signaling pathway	PIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIN1	0.520441272	0.45701325	0.05597015	201	4	0.022920657	FALSE	13.97857143	PIN1	PIN1	125.6318408	22.04978806	0	201	0	0.80197994	FALSE	0	PIN1	2473994	Infinity	0.0253342
787894	taxon:9606	2.19190169	3709.302682	0.00155982	178645	1902	proteasome 26S subunit, non-ATPase 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PSMD2			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD2	0.520441272	0.45622484	0.11578092	201	4	0.027086338	FALSE	28.53424658	PSMD2	PSMD2	147.5326633	47.39126064	0	200	0	0.80134972	FALSE	1	PSMD2	2351578	Infinity	0.02983973
788028	taxon:9606	2.22420041	2924.004128	0.00132792	178360	1902	ATP binding cassette subfamily E member 1	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006413-&&-translational initiation-%%-GO:0060702-&&-negative regulation of endoribonuclease activity-%%-GO:0006415-&&-translational termination-%%-GO:0016032-&&-viral process-%%-GO:0000054-&&-ribosomal subunit export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0060698-&&-endoribonuclease inhibitor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity	G:9606:ABCE1				ABCE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCE1	0.514762516	0.44959977	0.05035277	201	4	0.022631615	FALSE	14.68644068	ABCE1	ABCE1	118.0201005	20.59576721	0	200	0	0.7959666	FALSE	1	ABCE1	1939864	Infinity	0.02493239
793228	taxon:9606	2.1128092	4813.133258	0.00175319	180499	1902	heat shock protein family D (Hsp60) member 1	gene	biological_process-&-1&-GO:0051604-&&-protein maturation-%%-GO:0002368-&&-B cell cytokine production-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:0043627-&&-response to estrogen-%%-GO:0016032-&&-viral process-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0002931-&&-response to ischemia-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0002236-&&-detection of misfolded protein-%%-GO:0009408-&&-response to heat-%%-GO:0050821-&&-protein stabilization-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0033198-&&-response to ATP-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0009409-&&-response to cold-%%-GO:0042220-&&-response to cocaine-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0001666-&&-response to hypoxia-%%-GO:0042113-&&-B cell activation-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0045041-&&-protein import into mitochondrial intermembrane space-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042026-&&-protein refolding-%%-GO:0071866-&&-negative regulation of apoptotic process in bone marrow-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0014823-&&-response to activity-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:1903427-&&-negative regulation of reactive oxygen species biosynthetic process-%%-GO:1904469-&&-positive regulation of tumor necrosis factor secretion-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0002842-&&-positive regulation of T cell mediated immune response to tumor cell-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0048291-&&-isotype switching to IgG isotypes-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0042110-&&-T cell activation-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030061-&&-mitochondrial crista-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0046696-&&-lipopolysaccharide receptor complex-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030141-&&-secretory granule-%%-GO:0030135-&&-coated vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0042588-&&-zymogen granule-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0002039-&&-p53 binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0002020-&&-protease binding-%%-GO:0043559-&&-insulin binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:HSPD1			KEGG-&-1&-hsa04940-&&-Type I diabetes mellitus-%%-hsa05152-&&-Tuberculosis-%%-hsa05134-&&-Legionellosis-%%-hsa03018-&&-RNA degradation	HSPD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPD1	0.522305438	0.4733035	0.09740622	201	4	0.039172884	FALSE	26.22916667	HSPD1	HSPD1	198.5527638	32.9847359	0	200	0	0.8145318	FALSE	1	HSPD1	3332078	Infinity	0.036542
790150	taxon:9606	2.25949267	2600.498764	0.00153584	173760	1902	PAX interacting protein 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0000416-&&-positive regulation of histone H3-K36 methylation-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0006310-&&-DNA recombination-%%-GO:0060717-&&-chorion development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0060612-&&-adipose tissue development-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0045830-&&-positive regulation of isotype switching-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0051568-&&-histone H3-K4 methylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PAXIP1				PAXIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAXIP1	0.511969358	0.44257723	0.06084577	201	4	0.023598902	FALSE	15.16666667	PAXIP1	PAXIP1	116.4925373	20.12328962	0	201	0	0.79008455	FALSE	0	PAXIP1	2166014	Infinity	0.02589122
787451	taxon:9606	2.20939026	2595.371615	8.74E-04	179405	1902	mitogen-activated protein kinase kinase kinase 3	gene	biological_process-&-1&-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001568-&&-blood vessel development-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MAP3K3			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04912-&&-GnRH signaling pathway	MAP3K3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K3	0.519766688	0.45261356	0.08039789	200	4	0.030739101	FALSE	20.20805369	MAP3K3	MAP3K3	146.489899	29.36225661	0	199	0	0.79843496	FALSE	1	MAP3K3	1649818	Infinity	0.03035851
792387	taxon:9606	2.20466362	3596.712216	0.00162913	182110	1902	activating transcription factor 2	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0016573-&&-histone acetylation-%%-GO:1902110-&&-positive regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0032915-&&-positive regulation of transforming growth factor beta2 production-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0097186-&&-amelogenesis-%%-GO:0009414-&&-response to water deprivation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006970-&&-response to osmotic stress|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008140-&&-cAMP response element binding protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:ATF2			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF2	0.514762516	0.45358393	0.05686305	200	4	0.019566827	FALSE	14.77692308	ATF2	ATF2	112.5808081	24.01706737	0	199	0	0.79922273	FALSE	1	ATF2	2268748	Infinity	0.02320587
788969	taxon:9606	2.26028045	1139.956545	6.02E-04	176514	1902	ribosomal protein L14	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPL14			KEGG-&-1&-hsa03010-&&-Ribosome	RPL14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL14	0.517419355	0.44242298	0.29557789	200	4	0.055208027	FALSE	69.96226415	RPL14	RPL14	185.58	87.01567061	0	200	0	0.78995326	FALSE	0	RPL14	1240820	Infinity	0.04109967
787183	taxon:9606	2.2204191	2052.66467	0.0022272	179908	1902	SMAD family member 4	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0007492-&&-endoderm development-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0048859-&&-formation of anatomical boundary-%%-GO:1905305-&&-negative regulation of cardiac myofibril assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0060956-&&-endocardial cell differentiation-%%-GO:0051098-&&-regulation of binding-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0014033-&&-neural crest cell differentiation-%%-GO:0007411-&&-axon guidance-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0048589-&&-developmental growth-%%-GO:0072134-&&-nephrogenic mesenchyme morphogenesis-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007498-&&-mesoderm development-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0032525-&&-somite rostral/caudal axis specification-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072133-&&-metanephric mesenchyme morphogenesis-%%-GO:0003251-&&-positive regulation of cell proliferation involved in heart valve morphogenesis-%%-GO:0003190-&&-atrioventricular valve formation-%%-GO:0003220-&&-left ventricular cardiac muscle tissue morphogenesis-%%-GO:0051797-&&-regulation of hair follicle development-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0061040-&&-female gonad morphogenesis-%%-GO:0003360-&&-brainstem development-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0046881-&&-positive regulation of follicle-stimulating hormone secretion-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0060065-&&-uterus development-%%-GO:0008283-&&-cell proliferation-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0060021-&&-palate development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048733-&&-sebaceous gland development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007338-&&-single fertilization-%%-GO:0033686-&&-positive regulation of luteinizing hormone secretion-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0071773-&&-cellular response to BMP stimulus|cellular_component-&-1&-GO:0071141-&&-SMAD protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0032444-&&-activin responsive factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000988-&&-transcription factor activity, protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0005518-&&-collagen binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0030616-&&-transforming growth factor beta receptor, common-partner cytoplasmic mediator activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:SMAD4	SMAD4	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SMAD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD4	0.508560558	0.45036543	0.06324459	199	4	0.016589861	FALSE	18.57	SMAD4	SMAD4	107.8984772	24.69835201	0	198	0	0.79659682	FALSE	1	SMAD4	2649122	Infinity	0.02271435
787538	taxon:9606	2.14747125	2930.023593	0.00176139	179221	1902	protein phosphatase 2 catalytic subunit alpha	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0007498-&&-mesoderm development-%%-GO:0040008-&&-regulation of growth-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0008380-&&-RNA splicing-%%-GO:0010033-&&-response to organic substance-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0019932-&&-second-messenger-mediated signaling-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0050811-&&-GABA receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding	G:9606:PPP2CA			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04140-&&-Autophagy - animal-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04136-&&-Autophagy - other-%%-hsa03015-&&-mRNA surveillance pathway	PPP2CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2CA	0.517753389	0.46566398	0.08370133	199	4	0.02556134	FALSE	18.88976378	PPP2CA	PPP2CA	145.6884422	26.15163246	0	199	0	0.80875479	FALSE	0	PPP2CA	2569006	Infinity	0.02792818
787604	taxon:9606	2.18859304	3173.18407	0.00147152	179114	1902	nuclear factor kappa B subunit 1	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:1900127-&&-positive regulation of hyaluronan biosynthetic process-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0045083-&&-negative regulation of interleukin-12 biosynthetic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0032269-&&-negative regulation of cellular protein metabolic process-%%-GO:0032375-&&-negative regulation of cholesterol transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0010956-&&-negative regulation of calcidiol 1-monooxygenase activity-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:2000630-&&-positive regulation of miRNA metabolic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0071359-&&-cellular response to dsRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0010957-&&-negative regulation of vitamin D biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0035994-&&-response to muscle stretch|cellular_component-&-1&-GO:0035580-&&-specific granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0034774-&&-secretory granule lumen|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000975-&&-regulatory region DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042805-&&-actinin binding	G:9606:NFKB1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa05140-&&-Leishmaniasis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05134-&&-Legionellosis-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	NFKB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKB1	0.518758085	0.45691455	0.08800373	199	4	0.026479091	FALSE	22.4028777	NFKB1	NFKB1	136.2741117	32.29748046	0	198	0	0.80190116	FALSE	1	NFKB1	2215632	Infinity	0.0275073
788047	taxon:9606	2.20860249	1829.644387	4.01E-04	178311	1902	ribosomal protein L5	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008097-&&-5S rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL5			KEGG-&-1&-hsa03010-&&-Ribosome	RPL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL5	0.525384867	0.452775	0.31819124	199	4	0.056458119	FALSE	70.20348837	RPL5	RPL5	192.6497462	92.56266273	0	198	0	0.79856625	FALSE	1	RPL5	1065554	Infinity	0.03983659
792263	taxon:9606	2.34693556	2784.719486	0.0010266	182324	1902	CD81 molecule	gene	biological_process-&-1&-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0046813-&&-receptor-mediated virion attachment to host cell-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0008104-&&-protein localization-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0043128-&&-positive regulation of 1-phosphatidylinositol 4-kinase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0061462-&&-protein localization to lysosome-%%-GO:0008283-&&-cell proliferation-%%-GO:0031623-&&-receptor internalization-%%-GO:0050776-&&-regulation of immune response-%%-GO:1904352-&&-positive regulation of protein catabolic process in the vacuole-%%-GO:2000145-&&-regulation of cell motility|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:1990459-&&-transferrin receptor binding	G:9606:CD81			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05144-&&-Malaria	CD81	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD81	0.514597369	0.42608754	0.10898166	199	4	0.040171884	FALSE	26.54375	CD81	CD81	139.4923858	36.14970147	0	198	0	0.77551074	FALSE	1	CD81	2213230	Infinity	0.0352215
788475	taxon:9606	2.25492359	1768.049395	0.0012749	177573	1902	survival of motor neuron 2, centromeric	gene	biological_process-&-1&-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0007399-&&-nervous system development-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0043005-&&-neuron projection-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0032797-&&-SMN complex-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SMN2			KEGG-&-1&-hsa03013-&&-RNA transport	SMN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMN2	0.512132822	0.44347401	0.07992334	199	4	0.029881584	FALSE	21.87401575	SMN2	SMN2	132.2538071	28.02648743	0	198	0	0.79084607	FALSE	1	SMN2	2342218	Infinity	0.02904762
788477	taxon:9606	2.25492359	1768.049395	0.0012749	177574	1902	survival of motor neuron 1, telomeric	gene	biological_process-&-1&-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0007399-&&-nervous system development-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0043005-&&-neuron projection-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0032797-&&-SMN complex-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SMN1			KEGG-&-1&-hsa03013-&&-RNA transport	SMN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMN1	0.512132822	0.44347401	0.07992334	199	4	0.029881584	FALSE	21.87401575	SMN1	SMN1	132.2538071	28.02648743	0	198	0	0.79084607	FALSE	1	SMN1	2342218	Infinity	0.02904762
793038	taxon:9606	2.1939499	2894.102559	0.00157848	180855	1902	nuclear receptor subfamily 3 group C member 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043402-&&-glucocorticoid mediated signaling pathway-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0038051-&&-glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005496-&&-steroid binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004883-&&-glucocorticoid receptor activity-%%-GO:1990239-&&-steroid hormone binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NR3C1	NR3C1	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	NR3C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR3C1	0.514762516	0.45579892	0.0688905	199	4	0.021083727	FALSE	19.24409449	NR3C1	NR3C1	119.0913706	27.81585027	0	198	0	0.80100835	FALSE	1	NR3C1	2169948	Infinity	0.02419057
789702	taxon:9606	2.33968804	1403.072564	5.00E-04	174857	1902	NOP56 ribonucleoprotein	gene	biological_process-&-1&-GO:0000154-&&-rRNA modification-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005732-&&-small nucleolar ribonucleoprotein complex-%%-GO:0032040-&&-small-subunit processome-%%-GO:0070761-&&-pre-snoRNP complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:1990226-&&-histone methyltransferase binding	G:9606:NOP56			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NOP56	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP56	0.509368053	0.42740741	0.1925283	199	4	0.041650292	FALSE	46.61428571	NOP56	NOP56	139.2110553	57.32597142	0	199	0	0.77671866	FALSE	0	NOP56	894450	Infinity	0.03462712
792551	taxon:9606	2.17976997	2426.200244	0.005294	181821	1902	caveolin 1	gene	biological_process-&-1&-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0007595-&&-lactation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0070836-&&-caveola assembly-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0008104-&&-protein localization-%%-GO:0086098-&&-angiotensin-activated signaling pathway involved in heart process-%%-GO:0044860-&&-protein localization to plasma membrane raft-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:2000535-&&-regulation of entry of bacterium into host cell-%%-GO:0032507-&&-maintenance of protein location in cell-%%-GO:1900085-&&-negative regulation of peptidyl-tyrosine autophosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0060056-&&-mammary gland involution-%%-GO:0002931-&&-response to ischemia-%%-GO:0060355-&&-positive regulation of cell adhesion molecule production-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006816-&&-calcium ion transport-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0043627-&&-response to estrogen-%%-GO:0001525-&&-angiogenesis-%%-GO:0001570-&&-vasculogenesis-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0098903-&&-regulation of membrane repolarization during action potential-%%-GO:0031623-&&-receptor internalization-%%-GO:0009617-&&-response to bacterium-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1901979-&&-regulation of inward rectifier potassium channel activity-%%-GO:0019217-&&-regulation of fatty acid metabolic process-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0051899-&&-membrane depolarization-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:1903361-&&-protein localization to basolateral plasma membrane-%%-GO:0051592-&&-response to calcium ion-%%-GO:0030301-&&-cholesterol transport-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000165-&&-MAPK cascade-%%-GO:0016050-&&-vesicle organization-%%-GO:0042524-&&-negative regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010524-&&-positive regulation of calcium ion transport into cytosol-%%-GO:2000286-&&-receptor internalization involved in canonical Wnt signaling pathway-%%-GO:0019065-&&-receptor-mediated endocytosis of virus by host cell-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0031295-&&-T cell costimulation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0030879-&&-mammary gland development-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:1903598-&&-positive regulation of gap junction assembly-%%-GO:0019915-&&-lipid storage-%%-GO:0042310-&&-vasoconstriction-%%-GO:1901844-&&-regulation of cell communication by electrical coupling involved in cardiac conduction-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0051001-&&-negative regulation of nitric-oxide synthase activity-%%-GO:0048550-&&-negative regulation of pinocytosis-%%-GO:0052547-&&-regulation of peptidase activity-%%-GO:0001960-&&-negative regulation of cytokine-mediated signaling pathway-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:0032570-&&-response to progesterone-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0033484-&&-nitric oxide homeostasis-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0003057-&&-regulation of the force of heart contraction by chemical signal-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006874-&&-cellular calcium ion homeostasis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005929-&&-cilium-%%-GO:0043234-&&-protein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005768-&&-endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005622-&&-intracellular-%%-GO:0005901-&&-caveola-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0044325-&&-ion channel binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0015485-&&-cholesterol binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0070320-&&-inward rectifier potassium channel inhibitor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005113-&&-patched binding-%%-GO:0050998-&&-nitric-oxide synthase binding	G:9606:CAV1	CAV1	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells	CAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAV1	0.508721852	0.458764	0.04992151	198	4	0.014083658	FALSE	15.51546392	CAV1	CAV1	107.2806122	21.73431176	0	197	0	0.80337167	FALSE	1	CAV1	4976358	Infinity	0.02144838
787152	taxon:9606	2.18481172	3468.308801	0.00121613	179978	1902	lamin A/C	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0035105-&&-sterol regulatory element binding protein import into nucleus-%%-GO:0030951-&&-establishment or maintenance of microtubule cytoskeleton polarity-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0090343-&&-positive regulation of cell aging-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0072201-&&-negative regulation of mesenchymal cell proliferation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005638-&&-lamin filament-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:LMNA	LMNA	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04210-&&-Apoptosis-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	LMNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMNA	0.521117609	0.45770534	0.09288924	197	4	0.033773296	FALSE	23.84057971	LMNA	LMNA	169.6358974	31.07767272	0	196	0	0.80253138	FALSE	1	LMNA	2191424	Infinity	0.03403198
788263	taxon:9606	2.18402395	2305.427816	4.90E-04	177973	1902	ribosomal protein S3A	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0030154-&&-cell differentiation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS3A			KEGG-&-1&-hsa03010-&&-Ribosome	RPS3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS3A	0.526592252	0.45787044	0.32360021	196	4	0.059691016	FALSE	68.01111111	RPS3A	RPS3A	213.9591837	90.97007938	0	196	0	0.80266268	FALSE	0	RPS3A	1230700	Infinity	0.04287452
789082	taxon:9606	2.28076256	2426.70039	9.80E-04	176227	1902	lysine acetyltransferase 2B	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0043970-&&-histone H3-K9 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0048511-&&-rhythmic process-%%-GO:0006473-&&-protein acetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0018076-&&-N-terminal peptidyl-lysine acetylation-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010835-&&-regulation of protein ADP-ribosylation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0016032-&&-viral process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0018394-&&-peptidyl-lysine acetylation|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0031674-&&-I band-%%-GO:0000125-&&-PCAF complex-%%-GO:0042641-&&-actomyosin-%%-GO:0005634-&&-nucleus-%%-GO:0000776-&&-kinetochore-%%-GO:0031672-&&-A band-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004468-&&-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity	G:9606:KAT2B			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	KAT2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT2B	0.510990761	0.43844985	0.10603066	196	4	0.027213126	FALSE	26.72592593	KAT2B	KAT2B	136.4536083	37.53391867	0	195	0	0.78653957	FALSE	1	KAT2B	1731234	Infinity	0.03106867
787022	taxon:9606	2.25224516	2549.001384	0.00115262	180219	1902	eukaryotic translation initiation factor 6	gene	biological_process-&-1&-GO:0032868-&&-response to insulin-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:1902626-&&-assembly of large subunit precursor of preribosome-%%-GO:0006413-&&-translational initiation-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0000054-&&-ribosomal subunit export from nucleus-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0035195-&&-gene silencing by miRNA-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0045652-&&-regulation of megakaryocyte differentiation-%%-GO:0042256-&&-mature ribosome assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0043023-&&-ribosomal large subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0043022-&&-ribosome binding	G:9606:EIF6	EIF6	TRUE	KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	EIF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF6	0.512623841	0.4440014	0.08146973	195	4	0.028319201	FALSE	20.32231405	EIF6	EIF6	126.8615385	26.03925724	0	195	0	0.79129247	FALSE	0	EIF6	1630180	Infinity	0.02784204
787797	taxon:9606	2.18685993	1263.746328	0.00288259	178769	1902	protein kinase cAMP-activated catalytic subunit alpha	gene	biological_process-&-1&-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0001707-&&-mesoderm formation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:1901621-&&-negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0006397-&&-mRNA processing-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0070613-&&-regulation of protein processing-%%-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0034605-&&-cellular response to heat-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0007596-&&-blood coagulation-%%-GO:0048240-&&-sperm capacitation-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0001843-&&-neural tube closure-%%-GO:0071374-&&-cellular response to parathyroid hormone stimulus-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0043197-&&-dendritic spine-%%-GO:0034704-&&-calcium channel complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0097546-&&-ciliary base-%%-GO:0036126-&&-sperm flagellum-%%-GO:0016020-&&-membrane-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PRKACA			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04530-&&-Tight junction-%%-hsa04740-&&-Olfactory transduction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05030-&&-Cocaine addiction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04970-&&-Salivary secretion	PRKACA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKACA	0.507273877	0.45727666	0.03690193	195	4	0.014385946	FALSE	10.225	PRKACA	PRKACA	99.28205128	11.65721383	0	195	0	0.80219001	FALSE	0	PRKACA	2965630	Infinity	0.02004332
787453	taxon:9606	2.17724909	2859.832712	9.63E-04	179406	1902	mitogen-activated protein kinase kinase kinase 1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05161-&&-Hepatitis B	MAP3K1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K1	0.522986632	0.45929517	0.0973822	193	4	0.035729852	FALSE	23.50993377	MAP3K1	MAP3K1	159.7905759	31.84160222	0	192	0	0.80379182	FALSE	1	MAP3K1	1716412	Infinity	0.03171395
787536	taxon:9606	2.17283756	1886.6822	0.0016954	179231	1902	protein phosphatase 1 catalytic subunit gamma	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0051301-&&-cell division-%%-GO:0030182-&&-neuron differentiation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0043197-&&-dendritic spine-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0032154-&&-cleavage furrow-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005521-&&-lamin binding	G:9606:PPP1CC			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa04218-&&-Cellular senescence-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP1CC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1CC	0.514432328	0.46022768	0.07507556	193	4	0.023979494	FALSE	19.27522936	PPP1CC	PPP1CC	136.2435233	23.27158123	0	193	0	0.80452707	FALSE	0	PPP1CC	2397780	Infinity	0.02689595
792244	taxon:9606	2.41941075	3559.818843	7.80E-04	165973	1902	immunoglobulin superfamily member 8	gene	biological_process-&-1&-GO:0007338-&&-single fertilization-%%-GO:0007399-&&-nervous system development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:IGSF8				IGSF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGSF8	0.503768844	0.41332378	0.12273316	193	4	0.039413888	FALSE	28.26490066	IGSF8	IGSF8	133.1502591	36.2622711	0	193	0	0.76343154	FALSE	0	IGSF8	1845628	Infinity	0.03785315
792863	taxon:9606	2.22514574	1767.100617	9.77E-04	181255	1902	fibrillarin	gene	biological_process-&-1&-GO:0031167-&&-rRNA methylation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0048254-&&-snoRNA localization-%%-GO:1990258-&&-histone glutamine methylation-%%-GO:0006364-&&-rRNA processing-%%-GO:0008033-&&-tRNA processing-%%-GO:0000494-&&-box C/D snoRNA 3'-end processing|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0001651-&&-dense fibrillar component-%%-GO:0005694-&&-chromosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0016020-&&-membrane-%%-GO:0001652-&&-granular component-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008649-&&-rRNA methyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:1990259-&&-histone-glutamine methyltransferase activity	G:9606:FBL			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	FBL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBL	0.518422754	0.44940877	0.15414508	193	4	0.040836167	FALSE	36.56390977	FBL	FBL	173.5129534	44.23914669	0	193	0	0.79580904	FALSE	0	FBL	1654908	Infinity	0.03662601
793306	taxon:9606	2.19552545	2732.241531	0.00190855	180337	1902	huntingtin	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006915-&&-apoptotic process-%%-GO:0031587-&&-positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:1905337-&&-positive regulation of aggrephagy-%%-GO:0048513-&&-animal organ development-%%-GO:0007030-&&-Golgi organization-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:1904504-&&-positive regulation of lipophagy-%%-GO:0042297-&&-vocal learning-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0045724-&&-positive regulation of cilium assembly|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0030425-&&-dendrite-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005814-&&-centriole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005522-&&-profilin binding-%%-GO:0002039-&&-p53 binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0008134-&&-transcription factor binding	G:9606:HTT			KEGG-&-1&-hsa05016-&&-Huntington disease	HTT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTT	0.51393784	0.45547183	0.05146199	192	4	0.02091386	FALSE	15.23893805	HTT	HTT	124.3842105	19.86987119	0	191	0	0.80074576	FALSE	1	HTT	2421826	Infinity	0.02531374
790955	taxon:9606	2.28391366	2581.892474	7.50E-04	170619	1902	WW domain containing oxidoreductase	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0050662-&&-coenzyme binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0048037-&&-cofactor binding	G:9606:WWOX				WWOX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWOX	0.514927769	0.43784492	0.06359879	191	4	0.025868937	FALSE	15.06870229	WWOX	WWOX	116.1308901	20.56158331	0	191	0	0.78601439	FALSE	0	WWOX	1212832	Infinity	0.02654429
788814	taxon:9606	2.25838979	1880.786198	0.00145018	176817	1902	ubiquitin conjugating enzyme E2 D1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1902916-&&-positive regulation of protein polyubiquitination-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2D1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2D1	0.507755619	0.44279336	0.05274119	191	4	0.017110663	FALSE	15.08080808	UBE2D1	UBE2D1	109.7830688	19.78548587	0	190	0	0.79026837	FALSE	1	UBE2D1	2100480	Infinity	0.02419912
787201	taxon:9606	2.38222782	2005.957542	2.97E-04	179882	1902	mago homolog, exon junction complex core component	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006417-&&-regulation of translation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:MAGOH			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	MAGOH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGOH	0.511805999	0.41977513	0.11616794	190	4	0.039323512	FALSE	26.50322581	MAGOH	MAGOH	143.4148936	35.99157412	0	189	0	0.7696287	FALSE	1	MAGOH	812090	Infinity	0.03804977
788264	taxon:9606	2.19788877	1455.049843	2.91E-04	177972	1902	ribosomal protein S4, X-linked	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS4X			KEGG-&-1&-hsa03010-&&-Ribosome	RPS4X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS4X	0.526074123	0.45498208	0.35371763	190	4	0.05931839	FALSE	70.5	RPS4X	RPS4X	210.0842105	95.13061306	0	190	0	0.80035187	FALSE	0	RPS4X	924826	Infinity	0.04278701
792998	taxon:9606	2.24578541	1844.508576	0.00248363	181017	1902	Fos proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0034097-&&-response to cytokine-%%-GO:0051412-&&-response to corticosterone-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001661-&&-conditioned taste aversion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030431-&&-sleep-%%-GO:0006306-&&-DNA methylation-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007565-&&-female pregnancy-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0009629-&&-response to gravity-%%-GO:0006954-&&-inflammatory response-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007399-&&-nervous system development-%%-GO:0009416-&&-response to light stimulus-%%-GO:0009636-&&-response to toxic substance-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:FOS	FOS	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05140-&&-Leishmaniasis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05132-&&-Salmonella infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04713-&&-Circadian entrainment-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	FOS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOS	0.506793049	0.44527852	0.04738878	190	4	0.015058835	FALSE	13.25263158	FOS	FOS	95.40957447	17.28583134	0	189	0	0.7923691	FALSE	1	FOS	2840636	Infinity	0.02076218
787310	taxon:9606	2.16369939	2658.506703	0.00123244	179683	1902	karyopherin subunit beta 1	gene	biological_process-&-1&-GO:0040001-&&-establishment of mitotic spindle localization-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007079-&&-mitotic chromosome movement towards spindle pole-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0031291-&&-Ran protein signal transduction-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0019054-&&-modulation by virus of host process-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0006610-&&-ribosomal protein import into nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0034399-&&-nuclear periphery-%%-GO:0071782-&&-endoplasmic reticulum tubular network-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:KPNB1			KEGG-&-1&-hsa03013-&&-RNA transport	KPNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNB1	0.516919111	0.46217141	0.085504	189	4	0.031138573	FALSE	20.50387597	KPNB1	KPNB1	172.3903743	28.18216086	0	188	0	0.8060501	FALSE	1	KPNB1	2165840	Infinity	0.03362402
788779	taxon:9606	2.13234599	2540.953321	0.00217879	176918	1902	tubulin alpha 1a	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0051301-&&-cell division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0055037-&&-recycling endosome-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0019904-&&-protein domain specific binding	G:9606:TUBA1A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA1A	0.518925914	0.46896705	0.08262974	189	4	0.027076736	FALSE	19.51937984	TUBA1A	TUBA1A	159.0793651	25.791002	0	189	0	0.81127567	FALSE	0	TUBA1A	3006056	Infinity	0.0298823
788267	taxon:9606	2.22010399	1936.7144	3.05E-04	177969	1902	ribosomal protein S6	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0048821-&&-erythrocyte development-%%-GO:0002309-&&-T cell proliferation involved in immune response-%%-GO:0006413-&&-translational initiation-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0022605-&&-oogenesis stage-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0001890-&&-placenta development-%%-GO:0007369-&&-gastrulation-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006412-&&-translation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0019083-&&-viral transcription-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0031929-&&-TOR signaling|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005844-&&-polysome-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS6			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa03010-&&-Ribosome-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04066-&&-HIF-1 signaling pathway	RPS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6	0.523669605	0.45042935	0.35242917	188	4	0.056931317	FALSE	70.40462428	RPS6	RPS6	199.7393617	92.99087359	0	188	0	0.79664934	FALSE	0	RPS6	850838	Infinity	0.04183899
788626	taxon:9606	2.3349614	1993.682828	0.00100365	177290	1902	telomeric repeat binding factor 2	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1904354-&&-negative regulation of telomere capping-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0032205-&&-negative regulation of telomere maintenance-%%-GO:0090398-&&-cellular senescence-%%-GO:0000723-&&-telomere maintenance-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:1905778-&&-negative regulation of exonuclease activity-%%-GO:1904430-&&-negative regulation of t-circle formation-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0032214-&&-negative regulation of telomere maintenance via semi-conservative replication-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0031848-&&-protection from non-homologous end joining at telomere-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0032210-&&-regulation of telomere maintenance via telomerase-%%-GO:1905839-&&-negative regulation of telomeric D-loop disassembly-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0007049-&&-cell cycle-%%-GO:0016233-&&-telomere capping-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:1903824-&&-negative regulation of telomere single strand break repair-%%-GO:0031627-&&-telomeric loop formation-%%-GO:0032208-&&-negative regulation of telomere maintenance via recombination-%%-GO:1903770-&&-negative regulation of beta-galactosidase activity-%%-GO:0032204-&&-regulation of telomere maintenance|cellular_component-&-1&-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0070187-&&-shelterin complex-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0030870-&&-Mre11 complex-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0044877-&&-macromolecular complex binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003720-&&-telomerase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019899-&&-enzyme binding	G:9606:TERF2				TERF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERF2	0.50471995	0.4282726	0.04722024	186	4	0.018539058	FALSE	13.00943396	TERF2	TERF2	100.125	16.89127565	0	185	0	0.77750643	FALSE	1	TERF2	1402182	Infinity	0.02470746
788387	taxon:9606	2.17472822	2795.457733	0.00205628	177753	1902	signal transducer and activator of transcription 1	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0046725-&&-negative regulation by virus of viral protein levels in host cell-%%-GO:0072136-&&-metanephric mesenchymal cell proliferation involved in metanephros development-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0008015-&&-blood circulation-%%-GO:0072308-&&-negative regulation of metanephric nephron tubule epithelial cell differentiation-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0051591-&&-response to cAMP-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061326-&&-renal tubule development-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0051607-&&-defense response to virus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0034097-&&-response to cytokine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0003340-&&-negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0072162-&&-metanephric mesenchymal cell differentiation-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0016525-&&-negative regulation of angiogenesis|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0030425-&&-dendrite-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0019899-&&-enzyme binding	G:9606:STAT1	STAT1	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	STAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT1	0.512460064	0.45982757	0.06323185	185	4	0.017942138	FALSE	15.23148148	STAT1	STAT1	125.2786885	20.97686688	0	184	0	0.80421196	FALSE	1	STAT1	2698486	Infinity	0.02476518
788082	taxon:9606	2.19694344	1292.943626	2.94E-04	178268	1902	ribosomal protein lateral stalk subunit P0	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPLP0			KEGG-&-1&-hsa03010-&&-Ribosome	RPLP0	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPLP0	0.523840627	0.45517785	0.33891661	184	4	0.057507068	FALSE	67.15662651	RPLP0	RPLP0	217.9619565	82.76640988	0	184	0	0.80050943	FALSE	0	RPLP0	861332	Infinity	0.04428321
788692	taxon:9606	2.26091067	2946.795831	0.00129907	177168	1902	TNF receptor superfamily member 1A	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0006693-&&-prostaglandin metabolic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0006954-&&-inflammatory response-%%-GO:0006955-&&-immune response-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005739-&&-mitochondrion-%%-GO:0005615-&&-extracellular space-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043120-&&-tumor necrosis factor binding	G:9606:TNFRSF1A			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	TNFRSF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF1A	0.510015898	0.44229965	0.07856232	184	4	0.02275769	FALSE	18.48091603	TNFRSF1A	TNFRSF1A	124.2417582	28.99890344	0	183	0	0.78984822	FALSE	1	TNFRSF1A	1903146	Infinity	0.02751146
789092	taxon:9606	2.1476288	3586.550867	0.00165961	176205	1902	sequestosome 1	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006915-&&-apoptotic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000422-&&-mitophagy-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006914-&&-autophagy-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006950-&&-response to stress-%%-GO:0008104-&&-protein localization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0061635-&&-regulation of protein complex stability-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0016197-&&-endosomal transport-%%-GO:0002376-&&-immune system process|cellular_component-&-1&-GO:0044753-&&-amphisome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0097225-&&-sperm midpiece-%%-GO:0016605-&&-PML body-%%-GO:0005770-&&-late endosome-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0016235-&&-aggresome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016234-&&-inclusion body-%%-GO:0044754-&&-autolysosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:SQSTM1			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04217-&&-Necroptosis	SQSTM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SQSTM1	0.517419355	0.46562981	0.07516241	184	4	0.022310983	FALSE	18.3046875	SQSTM1	SQSTM1	145.6703297	27.69699593	0	183	0	0.80872853	FALSE	1	SQSTM1	2310518	Infinity	0.02784114
788053	taxon:9606	2.20308807	1871.779183	4.50E-04	178301	1902	ribosomal protein L13	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL13			KEGG-&-1&-hsa03010-&&-Ribosome	RPL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL13	0.522816167	0.45390832	0.29724374	183	4	0.051973149	FALSE	59.86875	RPL13	RPL13	200.1530055	73.97338369	0	183	0	0.79948532	FALSE	0	RPL13	1152760	Infinity	0.04099816
789236	taxon:9606	2.17157712	2573.981835	8.67E-04	175935	1902	RuvB like AAA ATPase 1	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0051301-&&-cell division-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006310-&&-DNA recombination-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0040008-&&-regulation of growth-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007283-&&-spermatogenesis-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion|cellular_component-&-1&-GO:0097255-&&-R2TP complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0000812-&&-Swr1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0031011-&&-Ino80 complex-%%-GO:0016020-&&-membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043141-&&-ATP-dependent 5'-3' DNA helicase activity-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding	G:9606:RUVBL1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	RUVBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUVBL1	0.519430052	0.46049481	0.10564764	183	4	0.031561043	FALSE	23.44444444	RUVBL1	RUVBL1	177.0662983	30.91232616	0	182	0	0.80473715	FALSE	1	RUVBL1	1780220	Infinity	0.03482597
789419	taxon:9606	2.19836143	1716.728326	9.75E-04	175527	1902	ribosomal protein L23	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005840-&&-ribosome-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0070180-&&-large ribosomal subunit rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL23			KEGG-&-1&-hsa03010-&&-Ribosome	RPL23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL23	0.520610191	0.45488425	0.3042695	183	4	0.049885545	FALSE	62.63291139	RPL23	RPL23	184.6338798	77.61008076	0	183	0	0.80027309	FALSE	0	RPL23	1616030	Infinity	0.03757734
791062	taxon:9606	2.21915866	3687.86355	9.77E-04	170191	1902	OTU deubiquitinase, ubiquitin aldehyde binding 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:2000780-&&-negative regulation of double-strand break repair-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:1901315-&&-negative regulation of histone H2A K63-linked ubiquitination-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0002250-&&-adaptive immune response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019784-&&-NEDD8-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:OTUB1				OTUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTUB1	0.514927769	0.45062123	0.06249233	181	4	0.021141781	FALSE	13.225	OTUB1	OTUB1	129.8895028	19.26181004	0	181	0	0.79680689	FALSE	0	OTUB1	1610006	Infinity	0.02713832
791277	taxon:9606	2.39183866	1450.186532	0.00133877	169406	1902	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0072686-&&-mitotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:HECW2				HECW2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HECW2	0.486945962	0.4180884	0.01569267	181	4	0.009746944	FALSE	6.055555556	HECW2	HECW2	65	7.261761514	0	180	0	0.76802689	FALSE	1	HECW2	1367756	Infinity	0.01770003
793308	taxon:9606	2.3133764	1597.962552	3.32E-04	180333	1902	hepatoma derived growth factor	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0008283-&&-cell proliferation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0008201-&&-heparin binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001222-&&-transcription corepressor binding	G:9606:HDGF				HDGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDGF	0.512787724	0.43226861	0.11006753	181	4	0.034443919	FALSE	23.35294118	HDGF	HDGF	152.8839779	29.27461093	0	181	0	0.78110393	FALSE	0	HDGF	888148	Infinity	0.03637365
788225	taxon:9606	2.28927052	3267.51135	0.00143944	178049	1902	tripartite motif containing 27	gene	biological_process-&-1&-GO:0070206-&&-protein trimerization-%%-GO:0002820-&&-negative regulation of adaptive immune response-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0090281-&&-negative regulation of calcium ion import-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1900041-&&-negative regulation of interleukin-2 secretion-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0072643-&&-interferon-gamma secretion-%%-GO:0008283-&&-cell proliferation-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045087-&&-innate immune response-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0051127-&&-positive regulation of actin nucleation|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0001650-&&-fibrillar center-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity	G:9606:TRIM27				TRIM27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM27	0.5071135	0.43682037	0.03954802	180	4	0.013047031	FALSE	11.22916667	TRIM27	TRIM27	96.70786517	16.43716786	0	179	0	0.78512158	FALSE	1	TRIM27	1873998	Infinity	0.02229177
792543	taxon:9606	2.23333859	2046.888649	0.00265946	181829	1902	caspase 8	gene	biological_process-&-1&-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0036462-&&-TRAIL-activated apoptotic signaling pathway-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0060715-&&-syncytiotrophoblast cell differentiation involved in labyrinthine layer development-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0039650-&&-suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0042110-&&-T cell activation-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0032025-&&-response to cobalt ion-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0046677-&&-response to antibiotic-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0006508-&&-proteolysis-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0042113-&&-B cell activation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0009409-&&-response to cold|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0044297-&&-cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0097342-&&-ripoptosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0097199-&&-cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0035877-&&-death effector domain binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP8	CASP8	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis-%%-hsa01524-&&-Platinum drug resistance	CASP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP8	0.503294634	0.44776014	0.05585516	179	4	0.012779553	FALSE	14.44318182	CASP8	CASP8	96.0960452	19.03521642	0	178	0	0.79444357	FALSE	1	CASP8	2663382	Infinity	0.02052235
788172	taxon:9606	2.19489523	2218.455778	0.0020064	178131	1902	Raf-1 proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007507-&&-heart development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030878-&&-thyroid gland development-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0035773-&&-insulin secretion involved in cellular response to glucose stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0060324-&&-face development-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0048538-&&-thymus development-%%-GO:0030168-&&-platelet activation-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008283-&&-cell proliferation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0042060-&&-wound healing-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045104-&&-intermediate filament cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016607-&&-nuclear speck-%%-GO:0031143-&&-pseudopodium|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0019899-&&-enzyme binding	G:9606:RAF1	RAF1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	RAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAF1	0.510828025	0.45560261	0.06837662	178	4	0.017125035	FALSE	16.75471698	RAF1	RAF1	123.7840909	22.60303073	0	177	0	0.8008508	FALSE	1	RAF1	2342998	Infinity	0.02507369
788489	taxon:9606	2.19300457	2178.852001	0.00168405	177558	1902	synuclein alpha	gene	biological_process-&-1&-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0006915-&&-apoptotic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0051585-&&-negative regulation of dopamine uptake involved in synaptic transmission-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0001774-&&-microglial cell activation-%%-GO:0010040-&&-response to iron(II) ion-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0010517-&&-regulation of phospholipase activity-%%-GO:0070495-&&-negative regulation of thrombin-activated receptor signaling pathway-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0007006-&&-mitochondrial membrane organization-%%-GO:0045920-&&-negative regulation of exocytosis-%%-GO:0050812-&&-regulation of acyl-CoA biosynthetic process-%%-GO:0006638-&&-neutral lipid metabolic process-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:1903421-&&-regulation of synaptic vesicle recycling-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:1905606-&&-regulation of presynapse assembly-%%-GO:0014048-&&-regulation of glutamate secretion-%%-GO:0050808-&&-synapse organization-%%-GO:0031623-&&-receptor internalization-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0060732-&&-positive regulation of inositol phosphate biosynthetic process-%%-GO:0032769-&&-negative regulation of monooxygenase activity-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0031648-&&-protein destabilization-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051622-&&-negative regulation of norepinephrine uptake-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:1902957-&&-negative regulation of mitochondrial electron transport, NADH to ubiquinone-%%-GO:1904715-&&-negative regulation of chaperone-mediated autophagy-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0040012-&&-regulation of locomotion-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0051612-&&-negative regulation of serotonin uptake-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:1903284-&&-positive regulation of glutathione peroxidase activity-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:1903426-&&-regulation of reactive oxygen species biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0032410-&&-negative regulation of transporter activity-%%-GO:0043030-&&-regulation of macrophage activation-%%-GO:0001956-&&-positive regulation of neurotransmitter secretion-%%-GO:1903285-&&-positive regulation of hydrogen peroxide catabolic process-%%-GO:0007568-&&-aging-%%-GO:0042775-&&-mitochondrial ATP synthesis coupled electron transport-%%-GO:0045963-&&-negative regulation of dopamine metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0035067-&&-negative regulation of histone acetylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005840-&&-ribosome-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0098794-&&-postsynapse-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005938-&&-cell cortex-%%-GO:0030054-&&-cell junction-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005764-&&-lysosome-%%-GO:0099512-&&-supramolecular fiber-%%-GO:0005737-&&-cytoplasm-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0016234-&&-inclusion body-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043195-&&-terminal bouton-%%-GO:0005615-&&-extracellular space-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0008198-&&-ferrous iron binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0060961-&&-phospholipase D inhibitor activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0070840-&&-dynein complex binding	G:9606:SNCA			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa05012-&&-Parkinson disease	SNCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNCA	0.510015898	0.4559954	0.05720779	178	4	0.017651992	FALSE	15.1047619	SNCA	SNCA	119.5795455	19.29683989	0	177	0	0.80116591	FALSE	1	SNCA	2052710	Infinity	0.0241506
788484	taxon:9606	2.26894596	2023.058066	0.0010867	177567	1902	small ubiquitin-like modifier 2	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016925-&&-protein sumoylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019789-&&-SUMO transferase activity	G:9606:SUMO2			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO2	0.509368053	0.44073328	0.06493506	178	4	0.022509422	FALSE	16.01818182	SUMO2	SUMO2	123.3579546	20.38025877	0	177	0	0.78850901	FALSE	1	SUMO2	1528986	Infinity	0.02758179
790853	taxon:9606	2.2569718	1477.688384	6.41E-04	170894	1902	defective in cullin neddylation 1 domain containing 1	gene	biological_process-&-1&-GO:0045116-&&-protein neddylation-%%-GO:0008150-&&-biological_process-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0032182-&&-ubiquitin-like protein binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0005515-&&-protein binding	G:9606:DCUN1D1				DCUN1D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCUN1D1	0.511479592	0.44307155	0.12910889	177	4	0.032069206	FALSE	27.58677686	DCUN1D1	DCUN1D1	145.1186441	33.50443372	0	177	0	0.7905047	FALSE	0	DCUN1D1	1180504	Infinity	0.03183124
787702	taxon:9606	2.17630377	2598.01805	0.00155187	178916	1902	polo like kinase 1	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0051297-&&-centrosome organization-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0051081-&&-nuclear envelope disassembly-%%-GO:0031648-&&-protein destabilization-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0016321-&&-female meiosis chromosome segregation-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000910-&&-cytokinesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0090435-&&-protein localization to nuclear envelope-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045143-&&-homologous chromosome segregation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0008283-&&-cell proliferation-%%-GO:0070194-&&-synaptonemal complex disassembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin-%%-GO:0005813-&&-centrosome-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0000795-&&-synaptonemal complex-%%-GO:0051233-&&-spindle midzone|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0010997-&&-anaphase-promoting complex binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding	G:9606:PLK1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	PLK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLK1	0.515093128	0.45949468	0.06640394	177	4	0.020236017	FALSE	17.18348624	PLK1	PLK1	139.4228571	22.73776369	0	176	0	0.80394937	FALSE	1	PLK1	2092910	Infinity	0.02758531
788197	taxon:9606	2.25413581	1703.609049	7.87E-04	178099	1902	RB binding protein 4, chromatin remodeling factor	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0016575-&&-histone deacetylation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0031497-&&-chromatin assembly-%%-GO:0060416-&&-response to growth hormone-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0016581-&&-NuRD complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0016580-&&-Sin3 complex-%%-GO:0016589-&&-NURF complex-%%-GO:0033186-&&-CAF-1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0042393-&&-histone binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:RBBP4			KEGG-&-1&-hsa04218-&&-Cellular senescence	RBBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP4	0.514432328	0.44362899	0.1680791	177	4	0.034667283	FALSE	34.58914729	RBBP4	RBBP4	183.4350283	42.13326465	0	177	0	0.79097736	FALSE	0	RBBP4	1640066	Infinity	0.04010645
792421	taxon:9606	2.23412636	1753.166362	0.00152545	182048	1902	casein kinase 2 alpha 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006915-&&-apoptotic process-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0097421-&&-liver regeneration-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071174-&&-mitotic spindle checkpoint-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:CSNK2A2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04520-&&-Adherens junction-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2A2	0.509206349	0.44760226	0.05354391	177	4	0.018434662	FALSE	12.35051546	CSNK2A2	CSNK2A2	120.8135593	14.91171817	0	177	0	0.79431227	FALSE	0	CSNK2A2	2005948	Infinity	0.02575139
788043	taxon:9606	2.21521979	1372.515911	2.18E-04	178312	1902	ribosomal protein L4	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL4			KEGG-&-1&-hsa03010-&&-Ribosome	RPL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL4	0.523327896	0.45142248	0.3812987	176	4	0.055935245	FALSE	69.20710059	RPL4	RPL4	211.3522727	89.24905849	0	176	0	0.79746337	FALSE	0	RPL4	701786	Infinity	0.04389219
788284	taxon:9606	2.22593351	1392.228083	2.01E-04	177955	1902	ribosomal protein S14	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0006412-&&-translation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0019083-&&-viral transcription|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0070181-&&-small ribosomal subunit rRNA binding	G:9606:RPS14			KEGG-&-1&-hsa03010-&&-Ribosome	RPS14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS14	0.522305438	0.44924972	0.36305195	176	4	0.057366326	FALSE	66.53892216	RPS14	RPS14	224.0170455	82.09802546	0	176	0	0.79567775	FALSE	0	RPS14	766766	Infinity	0.04717141
788138	taxon:9606	2.26579486	2481.970116	0.00109815	178174	1902	paxillin	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0007172-&&-signal complex assembly-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0006936-&&-muscle contraction-%%-GO:0060396-&&-growth hormone receptor signaling pathway|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005178-&&-integrin binding	G:9606:PXN			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection	PXN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PXN	0.512460064	0.44134622	0.09436752	175	4	0.027149877	FALSE	21.54761905	PXN	PXN	130.1387283	28.63988895	0	174	0	0.78903419	FALSE	1	PXN	1567278	Infinity	0.02897898
788277	taxon:9606	2.27304238	1502.122315	2.45E-04	177962	1902	ribosomal protein S7	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0030154-&&-cell differentiation-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0001843-&&-neural tube closure-%%-GO:0042274-&&-ribosomal small subunit biogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS7			KEGG-&-1&-hsa03010-&&-Ribosome	RPS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS7	0.519766688	0.439939	0.32788177	175	4	0.053982534	FALSE	61.24223602	RPS7	RPS7	208.8857143	75.04361979	0	175	0	0.78782627	FALSE	0	RPS7	746360	Infinity	0.04691696
788272	taxon:9606	2.29510005	2434.055053	3.32E-04	177964	1902	ribosomal protein S6 kinase B2	gene	biological_process-&-1&-GO:0043491-&&-protein kinase B signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0006412-&&-translation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045948-&&-positive regulation of translational initiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042277-&&-peptide binding-%%-GO:0004711-&&-ribosomal protein S6 kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:RPS6KB2			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	RPS6KB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KB2	0.518758085	0.43571085	0.08124795	175	4	0.033308093	FALSE	16.01351351	RPS6KB2	RPS6KB2	141.8685714	22.15692145	0	175	0	0.78414999	FALSE	0	RPS6KB2	780518	Infinity	0.03284358
788726	taxon:9606	2.18701749	1923.31872	8.78E-04	177105	1902	chaperonin containing TCP1 subunit 3	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0046931-&&-pore complex assembly-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0044297-&&-cell body-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CCT3				CCT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT3	0.517920568	0.45724371	0.12716763	174	4	0.031056991	FALSE	25.265625	CCT3	CCT3	180.0172414	33.1583997	0	174	0	0.80216375	FALSE	0	CCT3	1897340	Infinity	0.03601065
790092	taxon:9606	2.28391366	1705.804872	0.00122228	173889	1902	Fas associated factor family member 2	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0034389-&&-lipid particle organization-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005811-&&-lipid particle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0035473-&&-lipase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0055102-&&-lipase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:FAF2				FAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAF2	0.504402516	0.43784492	0.05541956	174	4	0.015895776	FALSE	13.39772727	FAF2	FAF2	105.7093023	16.86857978	0	173	0	0.78601439	FALSE	1	FAF2	1558578	Infinity	0.02412373
788046	taxon:9606	2.23113282	1028.206661	3.21E-04	178308	1902	ribosomal protein L7	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005844-&&-polysome-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding	G:9606:RPL7			KEGG-&-1&-hsa03010-&&-Ribosome	RPL7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL7	0.520779221	0.44820281	0.39456484	173	4	0.05660025	FALSE	72.03680982	RPL7	RPL7	216.619883	88.81652746	0	172	0	0.7948112	FALSE	1	RPL7	715580	Infinity	0.04590129
788065	taxon:9606	2.28958563	1122.837364	1.70E-04	178289	1902	ribosomal protein L24	gene	biological_process-&-1&-GO:0021554-&&-optic nerve development-%%-GO:0006412-&&-translation-%%-GO:1902626-&&-assembly of large subunit precursor of preribosome-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0006413-&&-translational initiation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0010458-&&-exit from mitosis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL24			KEGG-&-1&-hsa03010-&&-Ribosome	RPL24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL24	0.517920568	0.43676025	0.37276516	173	4	0.056070387	FALSE	67.77639752	RPL24	RPL24	213.7572254	81.19062423	0	173	0	0.78506906	FALSE	0	RPL24	680898	Infinity	0.04908185
788283	taxon:9606	2.20151253	1333.037711	2.66E-04	177952	1902	ribosomal protein S16	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0042274-&&-ribosomal small subunit biogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS16			KEGG-&-1&-hsa03010-&&-Ribosome	RPS16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS16	0.523327896	0.45423316	0.38412421	173	4	0.054126017	FALSE	69.52147239	RPS16	RPS16	209.2485549	87.08065753	0	173	0	0.79974791	FALSE	0	RPS16	862492	Infinity	0.04262549
792542	taxon:9606	2.21490468	2619.835164	0.00164823	181834	1902	caspase 3	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0030182-&&-neuron differentiation-%%-GO:0007507-&&-heart development-%%-GO:0007611-&&-learning or memory-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030220-&&-platelet formation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0032025-&&-response to cobalt ion-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0009749-&&-response to glucose-%%-GO:0042060-&&-wound healing-%%-GO:0043200-&&-response to amino acid-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0042493-&&-response to drug-%%-GO:0006915-&&-apoptotic process-%%-GO:0034349-&&-glial cell apoptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0035329-&&-hippo signaling-%%-GO:0006508-&&-proteolysis-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0001666-&&-response to hypoxia-%%-GO:0032355-&&-response to estradiol-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0009411-&&-response to UV-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016485-&&-protein processing-%%-GO:0045165-&&-cell fate commitment-%%-GO:0010165-&&-response to X-ray-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0035094-&&-response to nicotine-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0021766-&&-hippocampus development-%%-GO:0030889-&&-negative regulation of B cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0045121-&&-membrane raft-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004190-&&-aspartic-type endopeptidase activity-%%-GO:0005123-&&-death receptor binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0016005-&&-phospholipase A2 activator activity-%%-GO:0002020-&&-protease binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP3	CASP3	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa05012-&&-Parkinson disease-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05146-&&-Amoebiasis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa01524-&&-Platinum drug resistance	CASP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP3	0.512951711	0.4514867	0.05448916	173	4	0.015302277	FALSE	12.73333333	CASP3	CASP3	109.0877193	18.22913398	0	172	0	0.79751589	FALSE	1	CASP3	2012616	Infinity	0.02262276
790618	taxon:9606	2.26910351	1899.689859	0.00107158	171740	1902	ubiquitin C-terminal hydrolase L5	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006310-&&-DNA recombination-%%-GO:0048853-&&-forebrain morphogenesis-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0030901-&&-midbrain development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0031011-&&-Ino80 complex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0003723-&&-RNA binding	G:9606:UCHL5				UCHL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UCHL5	0.510340439	0.44070268	0.0994779	172	4	0.020772217	FALSE	24.13392857	UCHL5	UCHL5	123.1176471	32.00495562	0	171	0	0.78848275	FALSE	1	UCHL5	1536746	Infinity	0.02753478
787533	taxon:9606	2.26941862	1822.746856	8.39E-04	179232	1902	protein phosphatase 1 catalytic subunit beta	gene	biological_process-&-1&-GO:0005981-&&-regulation of glycogen catabolic process-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0051301-&&-cell division-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0042587-&&-glycogen granule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0000164-&&-protein phosphatase type 1 complex|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0017018-&&-myosin phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0050115-&&-myosin-light-chain-phosphatase activity	G:9606:PPP1CB	PPP1CB	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05034-&&-Alcoholism-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04218-&&-Cellular senescence-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP1CB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1CB	0.511316544	0.44064149	0.09506324	172	4	0.01946009	FALSE	18.50943396	PPP1CB	PPP1CB	118.5813954	25.5782991	0	172	0	0.78843023	FALSE	0	PPP1CB	1333674	Infinity	0.02646186
787645	taxon:9606	2.16763825	2156.675286	5.43E-04	179020	1902	Y-box binding protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0051154-&&-negative regulation of striated muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0070937-&&-CRD-mediated mRNA stability complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:YBX1				YBX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YBX1	0.519766688	0.46133159	0.15273234	172	4	0.038984906	FALSE	30.36879433	YBX1	YBX1	207.5941177	38.05729375	0	171	0	0.80539362	FALSE	1	YBX1	1291862	Infinity	0.04049037
792294	taxon:9606	2.25098472	2175.747055	0.00105749	182279	1902	cyclin dependent kinase 9	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0031297-&&-replication fork processing-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031056-&&-regulation of histone modification-%%-GO:0051147-&&-regulation of muscle cell differentiation-%%-GO:0070816-&&-phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0008283-&&-cell proliferation-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006281-&&-DNA repair-%%-GO:1903839-&&-positive regulation of mRNA 3'-UTR binding-%%-GO:0042493-&&-response to drug-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0071345-&&-cellular response to cytokine stimulus|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0000932-&&-P-body-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005694-&&-chromosome-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0019901-&&-protein kinase binding	G:9606:CDK9			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	CDK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK9	0.512460064	0.44425002	0.07455621	172	4	0.022438008	FALSE	16.30973451	CDK9	CDK9	128.9411765	20.69293778	0	171	0	0.79150255	FALSE	1	CDK9	1529572	Infinity	0.02805735
788330	taxon:9606	2.36568458	968.6397558	0.00184713	177872	1902	ataxin 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051168-&&-nuclear export-%%-GO:0006396-&&-RNA processing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0042272-&&-nuclear RNA export factor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0034046-&&-poly(G) binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008266-&&-poly(U) RNA binding	G:9606:ATXN1				ATXN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN1	0.488577521	0.42271062	0.03508528	172	4	0.013244417	FALSE	11.32352941	ATXN1	ATXN1	92.52352941	12.52123346	0	171	0	0.7723859	FALSE	1	ATXN1	2275296	Infinity	0.0239302
788815	taxon:9606	2.31384906	1397.890227	9.93E-04	176816	1902	ubiquitin conjugating enzyme E2 D2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2D2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05131-&&-Shigellosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2D2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2D2	0.503136763	0.43218031	0.06418378	172	4	0.014063331	FALSE	16.13953488	UBE2D2	UBE2D2	100.9941177	20.43033799	0	171	0	0.78102516	FALSE	1	UBE2D2	1464462	Infinity	0.02404062
790332	taxon:9606	2.28139278	2081.757873	9.69E-04	173297	1902	SIN3 transcription regulator family member A	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0010817-&&-regulation of hormone levels-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031937-&&-positive regulation of chromatin silencing-%%-GO:0034613-&&-cellular protein localization-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0051595-&&-response to methylglyoxal-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0048511-&&-rhythmic process-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0007568-&&-aging-%%-GO:1901675-&&-negative regulation of histone H3-K27 acetylation-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016575-&&-histone deacetylation-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006476-&&-protein deacetylation-%%-GO:0006260-&&-DNA replication-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:SIN3A			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05016-&&-Huntington disease	SIN3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIN3A	0.50952986	0.43832873	0.09302326	172	4	0.017812977	FALSE	17.87155963	SIN3A	SIN3A	118.0232558	24.20214617	0	172	0	0.78643454	FALSE	0	SIN3A	1461306	Infinity	0.0267917
793321	taxon:9606	2.19631322	1882.255233	0.00288476	180317	1902	hypoxia inducible factor 1 alpha subunit	gene	biological_process-&-1&-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0007165-&&-signal transduction-%%-GO:0014850-&&-response to muscle activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0007595-&&-lactation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061298-&&-retina vasculature development in camera-type eye-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0006089-&&-lactate metabolic process-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0001922-&&-B-1 B cell homeostasis-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1903715-&&-regulation of aerobic respiration-%%-GO:0032364-&&-oxygen homeostasis-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001525-&&-angiogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0061072-&&-iris morphogenesis-%%-GO:0060574-&&-intestinal epithelial cell maturation-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0046886-&&-positive regulation of hormone biosynthetic process-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0008542-&&-visual learning-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0051541-&&-elastin metabolic process-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032963-&&-collagen metabolic process-%%-GO:2001054-&&-negative regulation of mesenchymal cell apoptotic process-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0002248-&&-connective tissue replacement involved in inflammatory response wound healing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0070244-&&-negative regulation of thymocyte apoptotic process-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0051216-&&-cartilage development-%%-GO:0070101-&&-positive regulation of chemokine-mediated signaling pathway-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0097411-&&-hypoxia-inducible factor-1alpha signaling pathway-%%-GO:0042541-&&-hemoglobin biosynthetic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0010573-&&-vascular endothelial growth factor production-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0021502-&&-neural fold elevation formation-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0061030-&&-epithelial cell differentiation involved in mammary gland alveolus development-%%-GO:0001947-&&-heart looping-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0071347-&&-cellular response to interleukin-1|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0031514-&&-motile cilium-%%-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0019899-&&-enzyme binding	G:9606:HIF1A	HIF1A	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	HIF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIF1A	0.511479592	0.45530846	0.08235294	171	4	0.020484095	FALSE	19.20754717	HIF1A	HIF1A	139.251462	23.71723799	0	171	0	0.80061446	FALSE	0	HIF1A	3172660	Infinity	0.02825225
789795	taxon:9606	2.21364424	1767.846732	4.49E-04	174648	1902	heterogeneous nuclear ribonucleoprotein R	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing-%%-GO:0061157-&&-mRNA destabilization-%%-GO:0010467-&&-gene expression-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0007623-&&-circadian rhythm|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0030425-&&-dendrite-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0043679-&&-axon terminus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:HNRNPR				HNRNPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPR	0.519598316	0.45174377	0.2006192	171	4	0.042413924	FALSE	38.21527778	HNRNPR	HNRNPR	203.6959064	47.75938354	0	171	0	0.79772596	FALSE	0	HNRNPR	1044794	Infinity	0.04216313
787346	taxon:9606	2.22813928	1629.080883	5.71E-04	179619	1902	ribosomal protein SA	gene	biological_process-&-1&-GO:0000461-&&-endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0007155-&&-cell adhesion-%%-GO:0000447-&&-endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0006407-&&-rRNA export from nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0000028-&&-ribosomal small subunit assembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030686-&&-90S preribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005055-&&-laminin receptor activity-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPSA			KEGG-&-1&-hsa03010-&&-Ribosome	RPSA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPSA	0.521626016	0.44880498	0.32050122	170	4	0.050105847	FALSE	59.65359477	RPSA	RPSA	197.1764706	71.63870313	0	170	0	0.79531012	FALSE	0	RPSA	983708	Infinity	0.04157715
787698	taxon:9606	2.29809359	1087.745855	0.0014401	178927	1902	phospholipase C gamma 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0009395-&&-phospholipid catabolic process-%%-GO:0016477-&&-cell migration-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0007411-&&-axon guidance-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0016032-&&-viral process-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0045766-&&-positive regulation of angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0035254-&&-glutamate receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0004629-&&-phospholipase C activity-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor	G:9606:PLCG1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05225-&&-Hepatocellular carcinoma	PLCG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCG1	0.497827436	0.43514329	0.08485903	170	4	0.01142538	FALSE	16.28	PLCG1	PLCG1	95.37647059	20.11470769	0	170	0	0.78365107	FALSE	0	PLCG1	1749436	Infinity	0.02225136
788063	taxon:9606	2.27839924	949.218237	2.08E-04	178292	1902	ribosomal protein L23a	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0008283-&&-cell proliferation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031932-&&-TORC2 complex|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL23A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL23A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL23A	0.517586318	0.43890464	0.37932475	170	4	0.0519219	FALSE	69.14379085	RPL23A	RPL23A	199.3823529	83.08539908	0	170	0	0.78693346	FALSE	0	RPL23A	626584	Infinity	0.04499715
787409	taxon:9606	2.40050418	1034.335069	0.00112234	179476	1902	NCK adaptor protein 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1903679-&&-positive regulation of cap-independent translational initiation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0051707-&&-response to other organism-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0036493-&&-positive regulation of translation in response to endoplasmic reticulum stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007172-&&-signal complex assembly-%%-GO:0042110-&&-T cell activation-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0007015-&&-actin filament organization-%%-GO:1903676-&&-positive regulation of cap-dependent translational initiation-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane-%%-GO:0005840-&&-ribosome-%%-GO:0005634-&&-nucleus-%%-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0071074-&&-eukaryotic initiation factor eIF2 binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity	G:9606:NCK1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCK1	0.477380952	0.41657915	0.06008735	169	4	0.007473693	FALSE	12	NCK1	NCK1	69.52662722	14.59492136	0	169	0	0.76658264	FALSE	0	NCK1	1287570	Infinity	0.01902106
788951	taxon:9606	2.31117063	2277.335833	8.81E-04	176546	1902	OFD1, centriole and centriolar satellite protein	gene	biological_process-&-1&-GO:0007067-&&-mitotic nuclear division-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication-%%-GO:0060287-&&-epithelial cilium movement involved in determination of left/right asymmetry-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0034451-&&-centriolar satellite-%%-GO:0016020-&&-membrane-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0043014-&&-alpha-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0042802-&&-identical protein binding	G:9606:OFD1				OFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OFD1	0.505356018	0.43268116	0.07344347	169	4	0.012917088	FALSE	14.57731959	OFD1	OFD1	99.62874251	22.00932479	0	168	0	0.78147156	FALSE	1	OFD1	1219898	Infinity	0.02358768
788055	taxon:9606	2.22530329	1488.24131	3.00E-04	178303	1902	ribosomal protein L11	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL11			KEGG-&-1&-hsa03010-&&-Ribosome	RPL11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL11	0.519093851	0.44937695	0.38587111	168	4	0.052598167	FALSE	69.17419355	RPL11	RPL11	206.0119048	82.70587949	0	168	0	0.79578278	FALSE	0	RPL11	774538	Infinity	0.04327731
792635	taxon:9606	2.18055774	2048.400281	0.00105689	181679	1902	eukaryotic translation elongation factor 2	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0051593-&&-response to folic acid-%%-GO:0017183-&&-peptidyl-diphthamide biosynthetic process from peptidyl-histidine-%%-GO:0045727-&&-positive regulation of translation-%%-GO:2000767-&&-positive regulation of cytoplasmic translation-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0014009-&&-glial cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0002931-&&-response to ischemia-%%-GO:0006414-&&-translational elongation-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016235-&&-aggresome-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042788-&&-polysomal ribosome|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0008097-&&-5S rRNA binding	G:9606:EEF2			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	EEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF2	0.516752577	0.45859827	0.15458196	168	4	0.038097344	FALSE	32.66153846	EEF2	EEF2	189.0481928	38.60545403	0	167	0	0.80324038	FALSE	1	EEF2	1640344	Infinity	0.03749349
792680	taxon:9606	2.22293997	1989.240292	6.54E-04	181574	1902	drebrin 1	gene	biological_process-&-1&-GO:0032507-&&-maintenance of protein location in cell-%%-GO:0050773-&&-regulation of dendrite development-%%-GO:0010644-&&-cell communication by electrical coupling-%%-GO:0010643-&&-cell communication by chemical coupling-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0007015-&&-actin filament organization-%%-GO:0061351-&&-neural precursor cell proliferation|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005921-&&-gap junction-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0030425-&&-dendrite-%%-GO:0042641-&&-actomyosin|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005522-&&-profilin binding	G:9606:DBN1				DBN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBN1	0.511969358	0.4498547	0.12230741	168	4	0.023411658	FALSE	23.21367521	DBN1	DBN1	149.060241	33.48049801	0	167	0	0.79617667	FALSE	1	DBN1	1316628	Infinity	0.03124826
789479	taxon:9606	2.31369151	2100.193218	7.45E-04	175375	1902	nuclear receptor corepressor 1	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0072368-&&-regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051225-&&-spindle assembly-%%-GO:0072362-&&-regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000191-&&-regulation of fatty acid transport-%%-GO:0007623-&&-circadian rhythm-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0035257-&&-nuclear hormone receptor binding	G:9606:NCOR1	NCOR1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance	NCOR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOR1	0.509368053	0.43220974	0.14100037	168	4	0.024804754	FALSE	28.84552846	NCOR1	NCOR1	146.5662651	39.27883969	0	167	0	0.78105142	FALSE	1	NCOR1	1405496	Infinity	0.03479159
787096	taxon:9606	2.19379234	1612.429693	0.00156786	180063	1902	inhibitor of nuclear factor kappa B kinase subunit beta	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1903347-&&-negative regulation of bicellular tight junction assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0042501-&&-serine phosphorylation of STAT protein-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0009615-&&-response to virus-%%-GO:0035509-&&-negative regulation of myosin-light-chain-phosphatase activity-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005634-&&-nucleus-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0045121-&&-membrane raft-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008384-&&-IkappaB kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:IKBKB	IKBKB	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	IKBKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKB	0.511969358	0.45583166	0.09389496	166	4	0.019655338	FALSE	21.28181818	IKBKB	IKBKB	133.4573171	27.66747046	0	165	0	0.80103461	FALSE	1	IKBKB	2006686	Infinity	0.02689341
788818	taxon:9606	2.31589727	1480.111776	9.17E-04	176815	1902	ubiquitin conjugating enzyme E2 D3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2D3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2D3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2D3	0.502034429	0.43179808	0.04810714	166	4	0.014997507	FALSE	12.23863636	UBE2D3	UBE2D3	108.847561	14.96469622	0	165	0	0.78068379	FALSE	1	UBE2D3	1471018	Infinity	0.02597249
793361	taxon:9606	2.18402395	1743.856189	5.68E-04	180236	1902	heterogeneous nuclear ribonucleoprotein H1	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006396-&&-RNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0043484-&&-regulation of RNA splicing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPH1				HNRNPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPH1	0.51993517	0.45787044	0.17517342	166	4	0.039796259	FALSE	32.84172662	HNRNPH1	HNRNPH1	210.6746988	40.90217507	0	166	0	0.80266268	FALSE	0	HNRNPH1	1284532	Infinity	0.04194796
790285	taxon:9606	2.25082716	2025.363385	5.01E-04	173429	1902	splicing factor 3b subunit 1	gene	biological_process-&-1&-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0034693-&&-U11/U12 snRNP-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SF3B1	SF3B1	TRUE	KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B1	0.516752577	0.44428111	0.18116101	166	4	0.038854297	FALSE	34.45652174	SF3B1	SF3B1	200.7590361	43.99716813	0	166	0	0.79152881	FALSE	0	SF3B1	1163170	Infinity	0.04358642
793174	taxon:9606	2.29336695	1645.477784	0.00149256	180588	1902	golgin A2	gene	biological_process-&-1&-GO:0007020-&&-microtubule nucleation-%%-GO:0090166-&&-Golgi disassembly-%%-GO:0051297-&&-centrosome organization-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0006486-&&-protein glycosylation-%%-GO:0051225-&&-spindle assembly-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0060050-&&-positive regulation of protein glycosylation-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0090306-&&-spindle assembly involved in meiosis-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0090161-&&-Golgi ribbon formation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0000137-&&-Golgi cis cisterna-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0000922-&&-spindle pole-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0061676-&&-importin-alpha family protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0019905-&&-syntaxin binding	G:9606:GOLGA2				GOLGA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLGA2	0.50297899	0.43604012	0.03074649	165	4	0.012123046	FALSE	7.069444444	GOLGA2	GOLGA2	96.01818182	8.321108523	0	165	0	0.78443884	FALSE	0	GOLGA2	1802672	Infinity	0.02220164
789723	taxon:9606	2.16826847	1650.026534	7.15E-04	174823	1902	chaperonin containing TCP1 subunit 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0051086-&&-chaperone mediated protein folding independent of cofactor-%%-GO:0050821-&&-protein stabilization-%%-GO:1901998-&&-toxin transport-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0090666-&&-scaRNA localization to Cajal body-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0005576-&&-extracellular region-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CCT2				CCT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT2	0.516586151	0.4611975	0.14693274	165	4	0.032893483	FALSE	27.94354839	CCT2	CCT2	198.3272727	34.53396331	0	165	0	0.80528859	FALSE	0	CCT2	1673466	Infinity	0.03873343
792297	taxon:9606	2.20797227	1444.986106	0.00157577	182275	1902	cyclin dependent kinase inhibitor 2A	gene	biological_process-&-1&-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0035986-&&-senescence-associated heterochromatin focus assembly-%%-GO:0090399-&&-replicative senescence-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:2000111-&&-positive regulation of macrophage apoptotic process-%%-GO:0090398-&&-cellular senescence|cellular_component-&-1&-GO:0035985-&&-senescence-associated heterochromatin focus-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CDKN2A			KEGG-&-1&-hsa05219-&&-Bladder cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma	CDKN2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN2A	0.512296391	0.45290424	0.07376927	164	4	0.022582406	FALSE	16.58163265	CDKN2A	CDKN2A	142.1707317	18.80693615	0	164	0	0.79867129	FALSE	0	CDKN2A	1963422	Infinity	0.02921315
793360	taxon:9606	2.17787931	2035.709065	4.09E-04	180242	1902	heterogeneous nuclear ribonucleoprotein A2/B1	gene	biological_process-&-1&-GO:1990428-&&-miRNA transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1905663-&&-positive regulation of telomerase RNA reverse transcriptase activity-%%-GO:0044806-&&-G-quadruplex DNA unwinding-%%-GO:0050658-&&-RNA transport-%%-GO:0010467-&&-gene expression-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0006397-&&-mRNA processing-%%-GO:1904358-&&-positive regulation of telomere maintenance via telomere lengthening-%%-GO:0031053-&&-primary miRNA processing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015030-&&-Cajal body-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding-%%-GO:0043047-&&-single-stranded telomeric DNA binding-%%-GO:0097157-&&-pre-mRNA intronic binding	G:9606:HNRNPA2B1				HNRNPA2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA2B1	0.521795706	0.45916227	0.17644352	164	4	0.041086584	FALSE	32.79166667	HNRNPA2B1	HNRNPA2B1	216.4938272	41.26302063	0	163	0	0.80368678	FALSE	1	HNRNPA2B1	1098948	Infinity	0.04275755
787229	taxon:9606	2.18969592	2350.440087	7.96E-04	179831	1902	minichromosome maintenance complex component 7	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0071466-&&-cellular response to xenobiotic stimulus-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0042493-&&-response to drug-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000785-&&-chromatin-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:MCM7			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM7	0.518422754	0.45668442	0.14642857	163	4	0.034468502	FALSE	27.6640625	MCM7	MCM7	204.5403727	33.14321945	0	162	0	0.80171735	FALSE	1	MCM7	1614416	Infinity	0.04095598
788159	taxon:9606	2.28879786	1759.098947	0.00140772	178145	1902	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0051668-&&-localization within membrane-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0048870-&&-cell motility-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0031529-&&-ruffle organization-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0007411-&&-axon guidance-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0010310-&&-regulation of hydrogen peroxide metabolic process-%%-GO:0031295-&&-T cell costimulation-%%-GO:0045453-&&-bone resorption-%%-GO:0030168-&&-platelet activation-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0021831-&&-embryonic olfactory bulb interneuron precursor migration-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0043652-&&-engulfment of apoptotic cell-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0007155-&&-cell adhesion-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0032707-&&-negative regulation of interleukin-23 production-%%-GO:0048532-&&-anatomical structure arrangement-%%-GO:0014041-&&-regulation of neuron maturation-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0021799-&&-cerebral cortex radially oriented cell migration-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0060263-&&-regulation of respiratory burst-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0097178-&&-ruffle assembly-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0002551-&&-mast cell chemotaxis-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0008361-&&-regulation of cell size-%%-GO:0002093-&&-auditory receptor cell morphogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0021894-&&-cerebral cortex GABAergic interneuron development-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0051932-&&-synaptic transmission, GABAergic|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043197-&&-dendritic spine-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005925-&&-focal adhesion-%%-GO:0000242-&&-pericentriolar material-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0060091-&&-kinocilium-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001891-&&-phagocytic cup-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0042470-&&-melanosome-%%-GO:0030027-&&-lamellipodium-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0051022-&&-Rho GDP-dissociation inhibitor binding	G:9606:RAC1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04145-&&-Phagosome-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	RAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAC1	0.502821317	0.43691058	0.05201863	163	4	0.018532094	FALSE	13.74444444	RAC1	RAC1	123.0869565	16.18076759	0	162	0	0.78520036	FALSE	1	RAC1	1864770	Infinity	0.02829903
792686	taxon:9606	2.29336695	1653.791937	0.00132172	181563	1902	dynactin subunit 1	gene	biological_process-&-1&-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0051081-&&-nuclear envelope disassembly-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0010970-&&-transport along microtubule-%%-GO:0007399-&&-nervous system development-%%-GO:0090063-&&-positive regulation of microtubule nucleation-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032402-&&-melanosome transport|cellular_component-&-1&-GO:0005869-&&-dynactin complex-%%-GO:0000776-&&-kinetochore-%%-GO:0005874-&&-microtubule-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0030904-&&-retromer complex-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0030286-&&-dynein complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005813-&&-centrosome-%%-GO:0031252-&&-cell leading edge-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0070840-&&-dynein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0003774-&&-motor activity-%%-GO:0015631-&&-tubulin binding	G:9606:DCTN1	DCTN1	TRUE	KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05016-&&-Huntington disease	DCTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCTN1	0.503294634	0.43604012	0.04021739	163	4	0.01196612	FALSE	9.367088608	DCTN1	DCTN1	95.74534161	11.17589616	0	162	0	0.78443884	FALSE	1	DCTN1	1512690	Infinity	0.02209918
792673	taxon:9606	2.26563731	2747.006266	9.27E-04	181582	1902	death domain associated protein	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0034605-&&-cellular response to heat-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:0016032-&&-viral process-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0072738-&&-cellular response to diamide-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0034620-&&-cellular response to unfolded protein|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016604-&&-nuclear body-%%-GO:0070603-&&-SWI/SNF superfamily-type complex|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0002039-&&-p53 binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding	G:9606:DAXX			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	DAXX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAXX	0.510015898	0.44137691	0.11055901	163	4	0.025505168	FALSE	23.98387097	DAXX	DAXX	153.6832298	32.07704017	0	162	0	0.78906045	FALSE	1	DAXX	1580304	Infinity	0.03404932
788052	taxon:9606	2.27225461	607.9276516	2.15E-04	178306	1902	ribosomal protein L8	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:1990932-&&-5.8S rRNA binding	G:9606:RPL8			KEGG-&-1&-hsa03010-&&-Ribosome	RPL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL8	0.514762516	0.44009153	0.3898474	162	4	0.050352834	FALSE	69.39007092	RPL8	RPL8	206.8148148	79.21756479	0	162	0	0.78795757	FALSE	0	RPL8	588850	Infinity	0.04622593
788702	taxon:9606	2.22010399	1515.737396	6.88E-04	177153	1902	topoisomerase (DNA) I	gene	biological_process-&-1&-GO:0016310-&&-phosphorylation-%%-GO:0042493-&&-response to drug-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006265-&&-DNA topological change-%%-GO:0007623-&&-circadian rhythm-%%-GO:0016032-&&-viral process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006260-&&-DNA replication-%%-GO:0012501-&&-programmed cell death-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032922-&&-circadian regulation of gene expression|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031298-&&-replication fork protection complex-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0000932-&&-P-body-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003917-&&-DNA topoisomerase type I activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding	G:9606:TOP1	TOP1	TRUE		TOP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOP1	0.514927769	0.45042935	0.15566038	162	4	0.036191754	FALSE	31.23809524	TOP1	TOP1	201.68125	37.85452711	0	161	0	0.79664934	FALSE	1	TOP1	1347608	Infinity	0.04202047
788903	taxon:9606	2.2106507	1842.038761	0.00115035	176647	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0006713-&&-glucocorticoid catabolic process-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0014704-&&-intercalated disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:YWHAH			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis	YWHAH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAH	0.50952986	0.4523555	0.08915094	162	4	0.01910026	FALSE	17.95876289	YWHAH	YWHAH	144.43125	23.3474685	0	161	0	0.79822488	FALSE	1	YWHAH	1770724	Infinity	0.02971805
789500	taxon:9606	2.35434063	1570.788632	9.90E-04	175335	1902	IQ motif containing B1	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0048496-&&-maintenance of animal organ identity-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0045494-&&-photoreceptor cell maintenance|cellular_component-&-1&-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0032391-&&-photoreceptor connecting cilium|molecular_function-&-1&-GO:0005516-&&-calmodulin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:IQCB1				IQCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQCB1	0.492175514	0.42474737	0.04110114	162	4	0.014323903	FALSE	9.566666667	IQCB1	IQCB1	94.61111111	11.43951514	0	162	0	0.77427656	FALSE	0	IQCB1	1381602	Infinity	0.02401821
789888	taxon:9606	2.25445092	1970.46033	6.41E-04	174420	1902	activator of HSP90 ATPase activity 1	gene	biological_process-&-1&-GO:0006950-&&-response to stress-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:AHSA1	AHSA1	TRUE		AHSA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHSA1	0.51393784	0.44356699	0.10497661	162	4	0.029994693	FALSE	19.88617886	AHSA1	AHSA1	149.4135803	24.5278415	0	162	0	0.79092485	FALSE	0	AHSA1	1045880	Infinity	0.03258478
787173	taxon:9606	2.21222625	1408.750271	0.00165999	179926	1902	LYN proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0009743-&&-response to carbohydrate-%%-GO:0070447-&&-positive regulation of oligodendrocyte progenitor proliferation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0090025-&&-regulation of monocyte chemotaxis-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0070668-&&-positive regulation of mast cell proliferation-%%-GO:0034136-&&-negative regulation of toll-like receptor 2 signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0034144-&&-negative regulation of toll-like receptor 4 signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0002762-&&-negative regulation of myeloid leukocyte differentiation-%%-GO:0032868-&&-response to insulin-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:0002513-&&-tolerance induction to self antigen-%%-GO:0050855-&&-regulation of B cell receptor signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0002768-&&-immune response-regulating cell surface receptor signaling pathway-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0016032-&&-viral process-%%-GO:0043200-&&-response to amino acid-%%-GO:0070667-&&-negative regulation of mast cell proliferation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0002774-&&-Fc receptor mediated inhibitory signaling pathway-%%-GO:0070304-&&-positive regulation of stress-activated protein kinase signaling cascade-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0050663-&&-cytokine secretion-%%-GO:0009636-&&-response to toxic substance-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0007417-&&-central nervous system development-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0060369-&&-positive regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0031175-&&-neuron projection development-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0050707-&&-regulation of cytokine secretion-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0002902-&&-regulation of B cell apoptotic process-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0034605-&&-cellular response to heat-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0033003-&&-regulation of mast cell activation-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0009725-&&-response to hormone-%%-GO:0002431-&&-Fc receptor mediated stimulatory signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:2000670-&&-positive regulation of dendritic cell apoptotic process-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002553-&&-histamine secretion by mast cell-%%-GO:0042493-&&-response to drug-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006991-&&-response to sterol depletion-%%-GO:0007596-&&-blood coagulation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0048678-&&-response to axon injury-%%-GO:0045646-&&-regulation of erythrocyte differentiation-%%-GO:0042531-&&-positive regulation of tyrosine phosphorylation of STAT protein-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1902532-&&-negative regulation of intracellular signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030061-&&-mitochondrial crista-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034666-&&-integrin alpha2-beta1 complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0042629-&&-mast cell granule-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0043208-&&-glycosphingolipid binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005161-&&-platelet-derived growth factor receptor binding	G:9606:LYN			KEGG-&-1&-hsa04730-&&-Long-term depression-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04611-&&-Platelet activation-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	LYN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYN	0.502348888	0.45203333	0.06599793	161	4	0.014228372	FALSE	14.59259259	LYN	LYN	117.1509434	17.66676728	0	160	0	0.79796229	FALSE	1	LYN	2023276	Infinity	0.024162
787593	taxon:9606	2.33637939	1462.647012	7.58E-04	179127	1902	neurofibromin 2	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0001707-&&-mesoderm formation-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0035330-&&-regulation of hippo signaling-%%-GO:0014010-&&-Schwann cell proliferation-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:2000177-&&-regulation of neural precursor cell proliferation-%%-GO:0014013-&&-regulation of gliogenesis-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0007398-&&-ectoderm development-%%-GO:0042524-&&-negative regulation of tyrosine phosphorylation of Stat5 protein|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005912-&&-adherens junction-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0032587-&&-ruffle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:NF2			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction	NF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NF2	0.501563477	0.42801268	0.04585622	161	4	0.020273807	FALSE	11.8989899	NF2	NF2	108.2704403	14.03948201	0	160	0	0.7772701	FALSE	1	NF2	1073628	Infinity	0.02663315
787892	taxon:9606	2.21837088	1919.23509	9.69E-04	178648	1902	proteasome 26S subunit, ATPase 5	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0090261-&&-positive regulation of inclusion body assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016234-&&-inclusion body-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0098794-&&-postsynapse-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031531-&&-thyrotropin-releasing hormone receptor binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:PSMC5			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC5	0.514597369	0.45078125	0.15587931	161	4	0.023870114	FALSE	31.72807018	PSMC5	PSMC5	159.6352201	42.01998543	0	160	0	0.79693819	FALSE	1	PSMC5	1534178	Infinity	0.03317048
787965	taxon:9606	2.16590515	2029.55969	0.0011546	178492	1902	poly(rC) binding protein 1	gene	biological_process-&-1&-GO:0039694-&&-viral RNA genome replication-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0098847-&&-sequence-specific single stranded DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:PCBP1			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa04216-&&-Ferroptosis	PCBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBP1	0.515589842	0.46170073	0.10768634	161	4	0.02869154	FALSE	20.43859649	PCBP1	PCBP1	178.8695652	25.96092595	0	161	0	0.80568247	FALSE	0	PCBP1	1826242	Infinity	0.0348063
788280	taxon:9606	2.24610052	1055.273792	3.48E-04	177959	1902	ribosomal protein S10	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS10			KEGG-&-1&-hsa03010-&&-Ribosome	RPS10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS10	0.516419833	0.44521605	0.3552795	161	4	0.050427724	FALSE	63.34965035	RPS10	RPS10	216.5465839	71.51934684	0	161	0	0.79231658	FALSE	0	RPS10	844788	Infinity	0.04673735
793244	taxon:9606	2.42114385	1097.726794	9.27E-04	180462	1902	intercellular adhesion molecule 1	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0097368-&&-establishment of Sertoli cell barrier-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0046813-&&-receptor-mediated virion attachment to host cell-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0010477-&&-response to sulfur dioxide-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0032868-&&-response to insulin-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0002457-&&-T cell antigen processing and presentation-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0001975-&&-response to amphetamine-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0050776-&&-regulation of immune response-%%-GO:0050900-&&-leukocyte migration-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0034698-&&-response to gonadotropin-%%-GO:0043200-&&-response to amino acid-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0002438-&&-acute inflammatory response to antigenic stimulus-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0002291-&&-T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0044406-&&-adhesion of symbiont to host-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0002693-&&-positive regulation of cellular extravasation-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0001910-&&-regulation of leukocyte mediated cytotoxicity-%%-GO:0007569-&&-cell aging-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1904996-&&-positive regulation of leukocyte adhesion to vascular endothelial cell-%%-GO:0007155-&&-cell adhesion-%%-GO:0046688-&&-response to copper ion-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061028-&&-establishment of endothelial barrier|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0045121-&&-membrane raft-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0004872-&&-receptor activity-%%-GO:0001618-&&-virus receptor activity	G:9606:ICAM1	ICAM1	TRUE	KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05164-&&-Influenza A-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05416-&&-Viral myocarditis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	ICAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICAM1	0.496133622	0.41302792	0.14767932	161	4	0.036461111	FALSE	30.0390625	ICAM1	ICAM1	147.4213837	34.15889896	0	160	0	0.76314269	FALSE	1	ICAM1	2063890	Infinity	0.04176586
789496	taxon:9606	2.31700016	1677.860375	5.59E-04	175336	1902	mediator of DNA damage checkpoint 1	gene	biological_process-&-1&-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0031573-&&-intra-S DNA damage checkpoint|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005694-&&-chromosome|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070975-&&-FHA domain binding-%%-GO:0005515-&&-protein binding	G:9606:MDC1				MDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDC1	0.508560558	0.43159255	0.08454741	161	4	0.02138323	FALSE	17.08653846	MDC1	MDC1	130.5408805	21.13235274	0	160	0	0.78049997	FALSE	1	MDC1	972176	Infinity	0.0311048
787311	taxon:9606	2.16322672	2462.735607	9.50E-04	179682	1902	karyopherin subunit alpha 2	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0019054-&&-modulation by virus of host process-%%-GO:0006607-&&-NLS-bearing protein import into nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:KPNA2			KEGG-&-1&-hsa05164-&&-Influenza A	KPNA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA2	0.515921518	0.4622724	0.08780134	160	4	0.026751461	FALSE	18.70434783	KPNA2	KPNA2	180.4556962	24.46456752	0	159	0	0.80612888	FALSE	1	KPNA2	1674834	Infinity	0.03499671
787602	taxon:9606	2.2089176	2127.582651	0.00141163	179112	1902	NFKB inhibitor alpha	gene	biological_process-&-1&-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0097421-&&-liver regeneration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0070427-&&-nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0042345-&&-regulation of NF-kappaB import into nucleus-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0006915-&&-apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0070417-&&-cellular response to cold-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0010875-&&-positive regulation of cholesterol efflux|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding	G:9606:NFKBIA	NFKBIA	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	NFKBIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKBIA	0.516087516	0.45271041	0.08449569	160	4	0.021288967	FALSE	18.26548673	NFKBIA	NFKBIA	143.1012658	23.34296094	0	159	0	0.79851373	FALSE	1	NFKBIA	1752254	Infinity	0.02942953
792321	taxon:9606	2.28123523	1984.693789	0.00103813	182236	1902	cystic fibrosis transmembrane conductance regulator	gene	biological_process-&-1&-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0061024-&&-membrane organization-%%-GO:1902161-&&-positive regulation of cyclic nucleotide-gated ion channel activity-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0051454-&&-intracellular pH elevation-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0006810-&&-transport-%%-GO:0099133-&&-ATP hydrolysis coupled anion transmembrane transport-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030301-&&-cholesterol transport-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0048240-&&-sperm capacitation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:1902943-&&-positive regulation of voltage-gated chloride channel activity|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0034707-&&-chloride channel complex-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031205-&&-endoplasmic reticulum Sec complex-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0015106-&&-bicarbonate transmembrane transporter activity-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0043225-&&-ATPase-coupled anion transmembrane transporter activity-%%-GO:0005254-&&-chloride channel activity-%%-GO:0005260-&&-intracellular ATPase-gated chloride channel activity-%%-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0015108-&&-chloride transmembrane transporter activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0019869-&&-chloride channel inhibitor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding	G:9606:CFTR			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa02010-&&-ABC transporters-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04530-&&-Tight junction-%%-hsa04976-&&-Bile secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04972-&&-Pancreatic secretion	CFTR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFTR	0.506473003	0.438359	0.04539224	160	4	0.014665095	FALSE	11.23232323	CFTR	CFTR	104.5	14.89706665	0	159	0	0.7864608	FALSE	1	CFTR	1342648	Infinity	0.02371406
788422	taxon:9606	2.20450607	1981.479579	5.03E-04	177697	1902	splicing factor proline and glutamine rich	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1902177-&&-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045876-&&-positive regulation of sister chromatid cohesion-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0008380-&&-RNA splicing-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006397-&&-mRNA processing-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0042382-&&-paraspeckles-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:SFPQ				SFPQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFPQ	0.518087855	0.45361635	0.14730307	160	4	0.034650642	FALSE	28.00746269	SFPQ	SFPQ	195.2658228	35.05417005	0	159	0	0.79924899	FALSE	1	SFPQ	1094426	Infinity	0.0398232
788856	taxon:9606	2.27146683	1551.479773	7.55E-04	176744	1902	vinculin	gene	biological_process-&-1&-GO:0034333-&&-adherens junction assembly-%%-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0048675-&&-axon extension-%%-GO:0070527-&&-platelet aggregation-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006936-&&-muscle contraction-%%-GO:0043297-&&-apical junction assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007155-&&-cell adhesion-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0007160-&&-cell-matrix adhesion|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0043034-&&-costamere-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0002102-&&-podosome-%%-GO:0030055-&&-cell-substrate junction-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0002162-&&-dystroglycan binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003779-&&-actin binding	G:9606:VCL			KEGG-&-1&-hsa05146-&&-Amoebiasis-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction-%%-hsa05131-&&-Shigellosis	VCL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCL	0.509044748	0.44024416	0.09263888	160	4	0.023246948	FALSE	19.04672897	VCL	VCL	138.4556962	23.96398864	0	159	0	0.78808886	FALSE	1	VCL	1188250	Infinity	0.03096042
791099	taxon:9606	2.31085552	1679.024656	0.00111868	170055	1902	F-box and WD repeat domain containing 7	gene	biological_process-&-1&-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:1902806-&&-regulation of cell cycle G1/S phase transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0001944-&&-vasculature development-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:2000346-&&-negative regulation of hepatocyte proliferation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0016032-&&-viral process-%%-GO:0010868-&&-negative regulation of triglyceride biosynthetic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:2000639-&&-negative regulation of SREBP signaling pathway-%%-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0010883-&&-regulation of lipid storage-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:1903378-&&-positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990452-&&-Parkin-FBXW7-Cul1 ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0050816-&&-phosphothreonine binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042802-&&-identical protein binding	G:9606:FBXW7			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	FBXW7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW7	0.501720363	0.43274016	0.04940389	159	4	0.012464094	FALSE	9.768292683	FBXW7	FBXW7	93.60509554	12.32945895	0	158	0	0.78152408	FALSE	1	FBXW7	1293526	Infinity	0.02208329
787592	taxon:9606	2.31243107	1695.107063	6.75E-04	179125	1902	nuclear factor of activated T-cells 2	gene	biological_process-&-1&-GO:0001816-&&-cytokine production-%%-GO:0016477-&&-cell migration-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042493-&&-response to drug-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0014904-&&-myotube cell development-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0044798-&&-nuclear transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:NFATC2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NFATC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFATC2	0.506153361	0.43244532	0.06385759	159	4	0.0194041	FALSE	13.94174757	NFATC2	NFATC2	122.8853503	17.05373168	0	158	0	0.78126149	FALSE	1	NFATC2	1100998	Infinity	0.02901594
792134	taxon:9606	2.22120687	1960.730162	7.38E-04	182533	1902	actin gamma 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001895-&&-retina homeostasis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051592-&&-response to calcium ion-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0045214-&&-sarcomere organization-%%-GO:0034329-&&-cell junction assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005634-&&-nucleus-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0097433-&&-dense body-%%-GO:0030016-&&-myofibril-%%-GO:0005925-&&-focal adhesion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042802-&&-identical protein binding	G:9606:ACTG1			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05132-&&-Salmonella infection-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma	ACTG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTG1	0.51360871	0.4502057	0.09741957	159	4	0.026203049	FALSE	19.77118644	ACTG1	ACTG1	171.7515924	24.67268473	0	158	0	0.79646552	FALSE	1	ACTG1	1555912	Infinity	0.03584614
788279	taxon:9606	2.26406176	1037.440653	1.65E-04	177956	1902	ribosomal protein S13	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070181-&&-small ribosomal subunit rRNA binding-%%-GO:1990932-&&-5.8S rRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS13			KEGG-&-1&-hsa03010-&&-Ribosome	RPS13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS13	0.518087855	0.44168406	0.41437784	159	4	0.050859284	FALSE	68.5033557	RPS13	RPS13	207.3899371	80.94852474	0	159	0	0.78932304	FALSE	0	RPS13	567456	Infinity	0.04583203
788370	taxon:9606	2.21837088	1678.921287	0.00110699	177788	1902	SRSF protein kinase 1	gene	biological_process-&-1&-GO:0035092-&&-sperm chromatin condensation-%%-GO:0045087-&&-innate immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:SRPK1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	SRPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPK1	0.511642743	0.45078125	0.10182917	159	4	0.023451988	FALSE	22.125	SRPK1	SRPK1	144.5732484	26.68031176	0	158	0	0.79693819	FALSE	1	SRPK1	1480494	Infinity	0.0300341
788827	taxon:9606	2.27792658	1844.726296	7.76E-04	176800	1902	small ubiquitin-like modifier 1	gene	biological_process-&-1&-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050821-&&-protein stabilization-%%-GO:0045759-&&-negative regulation of action potential-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0060021-&&-palate development-%%-GO:0032880-&&-regulation of protein localization-%%-GO:1902260-&&-negative regulation of delayed rectifier potassium channel activity-%%-GO:0016925-&&-protein sumoylation-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0090204-&&-protein localization to nuclear pore-%%-GO:1901896-&&-positive regulation of calcium-transporting ATPase activity-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0030578-&&-PML body organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034605-&&-cellular response to heat-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0001741-&&-XY body-%%-GO:0016605-&&-PML body-%%-GO:0016607-&&-nuclear speck-%%-GO:0001650-&&-fibrillar center-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005730-&&-nucleolus-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000792-&&-heterochromatin-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097165-&&-nuclear stress granule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0031386-&&-protein tag	G:9606:SUMO1			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO1	0.509368053	0.43899571	0.07765801	159	4	0.017411249	FALSE	16.14	SUMO1	SUMO1	124.7834395	20.50430601	0	158	0	0.78701224	FALSE	1	SUMO1	1220842	Infinity	0.02806359
793140	taxon:9606	2.37025366	1564.560372	7.41E-04	164279	1902	centrosomal protein 128	gene	cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0000922-&&-spindle pole	G:9606:CEP128				CEP128	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP128	0.487982963	0.42189577	0.07515325	159	4	0.008014088	FALSE	11.925	CEP128	CEP128	79.14465409	16.89081316	0	159	0	0.77162439	FALSE	0	CEP128	952626	Infinity	0.02048462
789251	taxon:9606	2.30439578	1682.846208	0.00103968	175895	1902	dynein light chain LC8-type 1	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0035721-&&-intraciliary retrograde transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0044458-&&-motile cilium assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005886-&&-plasma membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005874-&&-microtubule-%%-GO:0005929-&&-cilium-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0097542-&&-ciliary tip-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003774-&&-motor activity	G:9606:DYNLL1			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption	DYNLL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNLL1	0.50062422	0.43395323	0.04695411	159	4	0.01595182	FALSE	11.24137931	DYNLL1	DYNLL1	108.3757962	13.59144806	0	158	0	0.7826007	FALSE	1	DYNLL1	1304676	Infinity	0.02539408
789662	taxon:9606	2.2635891	2691.980039	5.13E-04	174950	1902	protein arginine methyltransferase 5	gene	biological_process-&-1&-GO:0019918-&&-peptidyl-arginine methylation, to symmetrical-dimethyl arginine-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0097421-&&-liver regeneration-%%-GO:0043985-&&-histone H4-R3 methylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:1904992-&&-positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway-%%-GO:0090161-&&-Golgi ribbon formation-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008283-&&-cell proliferation-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0018216-&&-peptidyl-arginine methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034709-&&-methylosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0035243-&&-protein-arginine omega-N symmetric methyltransferase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0008327-&&-methyl-CpG binding	G:9606:PRMT5			KEGG-&-1&-hsa03013-&&-RNA transport	PRMT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT5	0.514267393	0.44177629	0.12869508	159	4	0.031360768	FALSE	24.61538462	PRMT5	PRMT5	180.4522293	31.56850813	0	158	0	0.78940182	FALSE	1	PRMT5	1180008	Infinity	0.03986732
789837	taxon:9606	2.34709311	2150.283096	5.20E-04	174542	1902	RNA binding protein with serine rich domain 1	gene	biological_process-&-1&-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0061574-&&-ASAP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding	G:9606:RNPS1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	RNPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNPS1	0.508238276	0.42605894	0.14218613	159	4	0.028072149	FALSE	25.60330579	RNPS1	RNPS1	140.3018868	32.9099904	0	159	0	0.77548448	FALSE	0	RNPS1	862390	Infinity	0.03494286
787871	taxon:9606	2.26500709	3112.255054	8.35E-04	178671	1902	proteasome subunit alpha 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA1			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA1	0.510665393	0.44149972	0.13680728	158	4	0.017104819	FALSE	27.59090909	PSMA1	PSMA1	130.1666667	37.79217272	0	157	0	0.78916549	FALSE	1	PSMA1	1328164	Infinity	0.02877528
788060	taxon:9606	2.25902001	671.2601703	1.31E-04	178298	1902	ribosomal protein L18	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL18			KEGG-&-1&-hsa03010-&&-Ribosome	RPL18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL18	0.517586318	0.44266983	0.44924615	158	4	0.053952079	FALSE	73.8590604	RPL18	RPL18	222.6582279	85.12622368	0	158	0	0.79016333	FALSE	0	RPL18	521810	Infinity	0.04884998
788050	taxon:9606	2.24121632	864.3604751	1.28E-04	178307	1902	ribosomal protein L7a	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0042788-&&-polysomal ribosome-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL7A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL7A	0.519430052	0.44618629	0.43094413	158	4	0.054831244	FALSE	70.39735099	RPL7A	RPL7A	232.0886076	81.99671058	0	158	0	0.79313061	FALSE	0	RPL7A	526466	Infinity	0.0496765
788281	taxon:9606	2.26563731	1220.960902	2.09E-04	177958	1902	ribosomal protein S11	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS11			KEGG-&-1&-hsa03010-&&-Ribosome	RPS11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS11	0.514432328	0.44137691	0.39635572	158	4	0.049390089	FALSE	66.16438356	RPS11	RPS11	205.0759494	76.43049389	0	158	0	0.78906045	FALSE	0	RPS11	615056	Infinity	0.04539087
788282	taxon:9606	2.28911297	909.34081	1.67E-04	177953	1902	ribosomal protein S15a	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0009615-&&-response to virus-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS15A			KEGG-&-1&-hsa03010-&&-Ribosome	RPS15A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS15A	0.516087516	0.43685044	0.41497105	158	4	0.049240701	FALSE	68.6442953	RPS15A	RPS15A	196.0576923	81.46117224	0	157	0	0.78514784	FALSE	1	RPS15A	462670	Infinity	0.04484247
788507	taxon:9606	2.43359067	918.7166711	0.00168674	177535	1902	superoxide dismutase 1	gene	biological_process-&-1&-GO:0042554-&&-superoxide anion generation-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0048678-&&-response to axon injury-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0001975-&&-response to amphetamine-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0007626-&&-locomotory behavior-%%-GO:0001895-&&-retina homeostasis-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0046677-&&-response to antibiotic-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0034465-&&-response to carbon monoxide-%%-GO:1902177-&&-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:0060087-&&-relaxation of vascular smooth muscle-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0033081-&&-regulation of T cell differentiation in thymus-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0060047-&&-heart contraction-%%-GO:0001890-&&-placenta development-%%-GO:0002576-&&-platelet degranulation-%%-GO:0035865-&&-cellular response to potassium ion-%%-GO:0050665-&&-hydrogen peroxide biosynthetic process-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0042493-&&-response to drug-%%-GO:0046620-&&-regulation of organ growth-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007566-&&-embryo implantation-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0097332-&&-response to antipsychotic drug-%%-GO:0045471-&&-response to ethanol-%%-GO:0007569-&&-cell aging-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0046688-&&-response to copper ion-%%-GO:0060052-&&-neurofilament cytoskeleton organization-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0009408-&&-response to heat-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0010033-&&-response to organic substance-%%-GO:0000303-&&-response to superoxide-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0048538-&&-thymus development-%%-GO:0045541-&&-negative regulation of cholesterol biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031045-&&-dense core granule-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005777-&&-peroxisome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004784-&&-superoxide dismutase activity-%%-GO:0030346-&&-protein phosphatase 2B binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:SOD1	SOD1	TRUE	KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa05016-&&-Huntington disease-%%-hsa05020-&&-Prion diseases-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04213-&&-Longevity regulating pathway - multiple species	SOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOD1	0.473295958	0.41091545	0.0573201	158	4	0.009105423	FALSE	11.36764706	SOD1	SOD1	73.55769231	13.06106517	0	157	0	0.76106822	FALSE	1	SOD1	1818600	Infinity	0.02129015
790889	taxon:9606	2.22467307	1419.964359	7.51E-04	170766	1902	LIM domain and actin binding 1	gene	biological_process-&-1&-GO:0030835-&&-negative regulation of actin filament depolymerization-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0031529-&&-ruffle organization|cellular_component-&-1&-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0032154-&&-cleavage furrow-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003785-&&-actin monomer binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:LIMA1				LIMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIMA1	0.511479592	0.44950425	0.1490488	156	4	0.025124481	FALSE	24.87037037	LIMA1	LIMA1	173.2692308	32.23021932	0	156	0	0.79588782	FALSE	0	LIMA1	1466510	Infinity	0.03630061
787630	taxon:9606	2.24357964	2042.438855	8.46E-04	179063	1902	notch 1	gene	biological_process-&-1&-GO:1901201-&&-regulation of extracellular matrix assembly-%%-GO:0003184-&&-pulmonary valve morphogenesis-%%-GO:0003192-&&-mitral valve formation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0006955-&&-immune response-%%-GO:0014807-&&-regulation of somitogenesis-%%-GO:0042246-&&-tissue regeneration-%%-GO:0045608-&&-negative regulation of auditory receptor cell differentiation-%%-GO:0060768-&&-regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030324-&&-lung development-%%-GO:0001708-&&-cell fate specification-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0072017-&&-distal tubule development-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0046533-&&-negative regulation of photoreceptor cell differentiation-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0003162-&&-atrioventricular node development-%%-GO:0003169-&&-coronary vein morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:2001027-&&-negative regulation of endothelial cell chemotaxis-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0035148-&&-tube formation-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0045603-&&-positive regulation of endothelial cell differentiation-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0048103-&&-somatic stem cell division-%%-GO:0003157-&&-endocardium development-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0003207-&&-cardiac chamber formation-%%-GO:0061384-&&-heart trabecula morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0021515-&&-cell differentiation in spinal cord-%%-GO:0060979-&&-vasculogenesis involved in coronary vascular morphogenesis-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0003209-&&-cardiac atrium morphogenesis-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0007386-&&-compartment pattern specification-%%-GO:1902263-&&-apoptotic process involved in embryonic digit morphogenesis-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0060411-&&-cardiac septum morphogenesis-%%-GO:0045955-&&-negative regulation of calcium ion-dependent exocytosis-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0007507-&&-heart development-%%-GO:0014031-&&-mesenchymal cell development-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0007440-&&-foregut morphogenesis-%%-GO:0009912-&&-auditory receptor cell fate commitment-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0003180-&&-aortic valve morphogenesis-%%-GO:0006959-&&-humoral immune response-%%-GO:0003219-&&-cardiac right ventricle formation-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:1903849-&&-positive regulation of aorta morphogenesis-%%-GO:0060842-&&-arterial endothelial cell differentiation-%%-GO:0030900-&&-forebrain development-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0060843-&&-venous endothelial cell differentiation-%%-GO:0070986-&&-left/right axis specification-%%-GO:0003214-&&-cardiac left ventricle morphogenesis-%%-GO:0007409-&&-axonogenesis-%%-GO:0031960-&&-response to corticosteroid-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:2000974-&&-negative regulation of pro-B cell differentiation-%%-GO:0003273-&&-cell migration involved in endocardial cushion formation-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0003270-&&-Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation-%%-GO:0060956-&&-endocardial cell differentiation-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0003256-&&-regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:0060948-&&-cardiac vascular smooth muscle cell development-%%-GO:0007221-&&-positive regulation of transcription of Notch receptor target-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:0003213-&&-cardiac right atrium morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0072602-&&-interleukin-4 secretion-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0060271-&&-cilium assembly-%%-GO:0072044-&&-collecting duct development-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:0003160-&&-endocardium morphogenesis-%%-GO:0072144-&&-glomerular mesangial cell development-%%-GO:0021915-&&-neural tube development-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0007492-&&-endoderm development-%%-GO:0001947-&&-heart looping-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0003344-&&-pericardium morphogenesis-%%-GO:0003241-&&-growth involved in heart morphogenesis-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0001889-&&-liver development-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005912-&&-adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus-%%-GO:0002193-&&-MAML1-RBP-Jkappa- ICN1 complex-%%-GO:0009986-&&-cell surface-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0004872-&&-receptor activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0005112-&&-Notch binding	G:9606:NOTCH1	NOTCH1	TRUE	KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05020-&&-Prion diseases-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection	NOTCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH1	0.510015898	0.44571629	0.05890841	156	4	0.017664518	FALSE	13.32692308	NOTCH1	NOTCH1	125.6688312	16.5565132	0	155	0	0.79273673	FALSE	1	NOTCH1	1221074	Infinity	0.02700115
791977	taxon:9606	2.30801954	1435.459915	0.00129226	182782	1902	APC, WNT signaling pathway regulator	gene	biological_process-&-1&-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007050-&&-cell cycle arrest-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007155-&&-cell adhesion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005813-&&-centrosome-%%-GO:0016342-&&-catenin complex-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0008017-&&-microtubule binding	G:9606:APC	APC	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	APC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APC	0.500468019	0.4332719	0.04099822	156	4	0.012940872	FALSE	10.46987952	APC	APC	99.44805195	12.71107761	0	155	0	0.78199674	FALSE	1	APC	1434098	Infinity	0.02345295
787900	taxon:9606	2.20277296	2474.823303	5.88E-04	178643	1902	proteasome 26S subunit, non-ATPase 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043248-&&-proteasome assembly-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0005634-&&-nucleus-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:PSMD4			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD4	0.516752577	0.45397325	0.16781258	156	4	0.025025809	FALSE	30.456	PSMD4	PSMD4	172.7597403	43.38094019	0	155	0	0.79953784	FALSE	1	PSMD4	1253604	Infinity	0.03517812
792279	taxon:9606	2.29636049	1824.153071	0.00135886	182306	1902	cell division cycle 42	gene	biological_process-&-1&-GO:0036336-&&-dendritic cell migration-%%-GO:0034613-&&-cellular protein localization-%%-GO:0031424-&&-keratinization-%%-GO:0060047-&&-heart contraction-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0060501-&&-positive regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007097-&&-nuclear migration-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0031295-&&-T cell costimulation-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0072384-&&-organelle transport along microtubule-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0048664-&&-neuron fate determination-%%-GO:0035088-&&-establishment or maintenance of apical/basal cell polarity-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0090135-&&-actin filament branching-%%-GO:0007596-&&-blood coagulation-%%-GO:0007030-&&-Golgi organization-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0060661-&&-submandibular salivary gland formation-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0071338-&&-positive regulation of hair follicle cell proliferation-%%-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0003334-&&-keratinocyte development-%%-GO:0060684-&&-epithelial-mesenchymal cell signaling-%%-GO:0032488-&&-Cdc42 protein signal transduction-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0046847-&&-filopodium assembly-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0099563-&&-modification of synaptic structure-%%-GO:0051835-&&-positive regulation of synapse structural plasticity-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0034332-&&-adherens junction organization-%%-GO:0003161-&&-cardiac conduction system development-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0030496-&&-midbody-%%-GO:0043005-&&-neuron projection-%%-GO:0043209-&&-myelin sheath-%%-GO:0005925-&&-focal adhesion-%%-GO:0051233-&&-spindle midzone-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000322-&&-storage vacuole-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0031256-&&-leading edge membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030141-&&-secretory granule-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0051022-&&-Rho GDP-dissociation inhibitor binding-%%-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0034191-&&-apolipoprotein A-I receptor binding	G:9606:CDC42	CDC42	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04530-&&-Tight junction-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05131-&&-Shigellosis-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	CDC42	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC42	0.502506266	0.4354717	0.03879127	156	4	0.011971752	FALSE	9.95	CDC42	CDC42	96.42207792	12.31453837	0	155	0	0.78393992	FALSE	1	CDC42	1526856	Infinity	0.02233875
788287	taxon:9606	2.23979833	1054.476882	2.87E-04	177948	1902	ribosomal protein S19	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006413-&&-translational initiation-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0007000-&&-nucleolus organization-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0060265-&&-positive regulation of respiratory burst involved in inflammatory response-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0060266-&&-negative regulation of respiratory burst involved in inflammatory response-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0009991-&&-response to extracellular stimulus-%%-GO:0019083-&&-viral transcription-%%-GO:0051262-&&-protein tetramerization-%%-GO:0007219-&&-Notch signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005840-&&-ribosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017134-&&-fibroblast growth factor binding	G:9606:RPS19			KEGG-&-1&-hsa03010-&&-Ribosome	RPS19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS19	0.516419833	0.44646877	0.38171632	156	4	0.047938842	FALSE	65.01408451	RPS19	RPS19	204.6883117	73.55282408	0	155	0	0.79336695	FALSE	1	RPS19	703496	Infinity	0.04372748
789378	taxon:9606	2.22955727	1763.653402	7.19E-04	175627	1902	aurora kinase B	gene	biological_process-&-1&-GO:0051256-&&-mitotic spindle midzone assembly-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0036089-&&-cleavage furrow formation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0031577-&&-spindle checkpoint-%%-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0016570-&&-histone modification-%%-GO:0008283-&&-cell proliferation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009838-&&-abscission-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0034501-&&-protein localization to kinetochore-%%-GO:0007051-&&-spindle organization-%%-GO:0043988-&&-histone H3-S28 phosphorylation-%%-GO:0032466-&&-negative regulation of cytokinesis-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0007568-&&-aging-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0032091-&&-negative regulation of protein binding|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0051233-&&-spindle midzone-%%-GO:1990023-&&-mitotic spindle midzone-%%-GO:0005876-&&-spindle microtubule-%%-GO:0010369-&&-chromocenter-%%-GO:0030496-&&-midbody-%%-GO:0032133-&&-chromosome passenger complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031616-&&-spindle pole centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0000779-&&-condensed chromosome, centromeric region|molecular_function-&-1&-GO:0035174-&&-histone serine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:AURKB				AURKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AURKB	0.512951711	0.44851954	0.09438927	156	4	0.025860555	FALSE	18.34579439	AURKB	AURKB	170.2597403	22.0663616	0	155	0	0.79507379	FALSE	1	AURKB	1321270	Infinity	0.03582017
790286	taxon:9606	2.26264377	1384.713422	4.75E-04	173430	1902	splicing factor 3b subunit 3	gene	biological_process-&-1&-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0006461-&&-protein complex assembly-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SF3B3			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B3	0.514432328	0.44196087	0.19702233	156	4	0.036096603	FALSE	35.62992126	SF3B3	SF3B3	198.3525641	42.84468771	0	156	0	0.78955937	FALSE	0	SF3B3	986634	Infinity	0.04370501
787762	taxon:9606	2.19993698	1176.621342	0.00176839	178827	1902	peroxisome proliferator activated receptor gamma	gene	biological_process-&-1&-GO:0071306-&&-cellular response to vitamin E-%%-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0007507-&&-heart development-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0031000-&&-response to caffeine-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0043627-&&-response to estrogen-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045165-&&-cell fate commitment-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:1901558-&&-response to metformin-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000230-&&-negative regulation of pancreatic stellate cell proliferation-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0045087-&&-innate immune response-%%-GO:0010891-&&-negative regulation of sequestering of triglyceride-%%-GO:0033189-&&-response to vitamin A-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0010871-&&-negative regulation of receptor biosynthetic process-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0033993-&&-response to lipid-%%-GO:0010887-&&-negative regulation of cholesterol storage-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0048511-&&-rhythmic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0001890-&&-placenta development-%%-GO:0007584-&&-response to nutrient-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0009409-&&-response to cold-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:0046321-&&-positive regulation of fatty acid oxidation-%%-GO:0048469-&&-cell maturation-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042594-&&-response to starvation-%%-GO:0055098-&&-response to low-density lipoprotein particle-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0015909-&&-long-chain fatty acid transport-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0060694-&&-regulation of cholesterol transporter activity-%%-GO:0045713-&&-low-density lipoprotein particle receptor biosynthetic process-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:0060336-&&-negative regulation of interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0050544-&&-arachidonic acid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004955-&&-prostaglandin receptor activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008144-&&-drug binding	G:9606:PPARG	PPARG	TRUE	KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04714-&&-Thermogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04211-&&-Longevity regulating pathway	PPARG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARG	0.507916403	0.45455848	0.07997936	155	4	0.015466535	FALSE	18.17777778	PPARG	PPARG	130.254902	21.71359669	0	154	0	0.8000105	FALSE	1	PPARG	2038566	Infinity	0.02643841
788270	taxon:9606	2.28990074	831.3063604	1.67E-04	177970	1902	ribosomal protein S5	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0006450-&&-regulation of translational fidelity-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS5			KEGG-&-1&-hsa03010-&&-Ribosome	RPS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS5	0.514432328	0.43670015	0.38617512	155	4	0.048291575	FALSE	63.81560284	RPS5	RPS5	203.0903226	71.38190726	0	155	0	0.78501654	FALSE	0	RPS5	483088	Infinity	0.04650568
792698	taxon:9606	2.20293052	2042.897141	3.30E-04	181550	1902	DEAD-box helicase 3, X-linked	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0034063-&&-stress granule assembly-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0071470-&&-cellular response to osmotic stress-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0071651-&&-positive regulation of chemokine (C-C motif) ligand 5 production-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0045087-&&-innate immune response-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0071243-&&-cellular response to arsenic-containing substance-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0042256-&&-mature ribosome assembly-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0009615-&&-response to virus-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008190-&&-eukaryotic initiation factor 4E binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043273-&&-CTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0017111-&&-nucleoside-triphosphatase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:DDX3X			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05161-&&-Hepatitis B	DDX3X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX3X	0.520272462	0.45394078	0.15232509	155	4	0.038343728	FALSE	25.65693431	DDX3X	DDX3X	217.1870968	33.90182762	0	155	0	0.79951158	FALSE	0	DDX3X	961206	Infinity	0.0442143
793284	taxon:9606	2.35418308	791.5224143	4.54E-04	180378	1902	histone cluster 1 H2B family member d	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BD			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BD	0.497364341	0.4247758	0.02798492	155	4	0.01435821	FALSE	5.846153846	HIST1H2BD	HIST1H2BD	104.083871	6.895974741	0	155	0	0.77430282	FALSE	0	HIST1H2BD	1209660	Infinity	0.02627275
789918	taxon:9606	2.24074366	2052.796426	7.56E-04	174367	1902	KH RNA binding domain containing, signal transduction associated 1	gene	biological_process-&-1&-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0046833-&&-positive regulation of RNA export from nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0046831-&&-regulation of RNA export from nucleus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0070618-&&-Grb2-Sos complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding	G:9606:KHDRBS1				KHDRBS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KHDRBS1	0.51360871	0.44628041	0.10319917	155	4	0.026649296	FALSE	20.8125	KHDRBS1	KHDRBS1	180.6339869	25.80258278	0	154	0	0.79320939	FALSE	1	KHDRBS1	1528056	Infinity	0.0386533
790503	taxon:9606	2.30313534	1340.083783	6.12E-04	172661	1902	F-box protein 25	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:FBXO25			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway	FBXO25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO25	0.505834122	0.43419072	0.05379137	155	4	0.01952262	FALSE	10.64705882	FBXO25	FBXO25	116.5032258	12.61222263	0	155	0	0.78281078	FALSE	0	FBXO25	924544	Infinity	0.02720649
787688	taxon:9606	2.15802741	1843.278279	8.44E-04	178946	1902	pyruvate kinase, muscle	gene	biological_process-&-1&-GO:0012501-&&-programmed cell death-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005929-&&-cilium-%%-GO:0031982-&&-vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004743-&&-pyruvate kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0045296-&&-cadherin binding	G:9606:PKM			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00230-&&-Purine metabolism-%%-hsa05165-&&-Human papillomavirus infection	PKM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKM	0.515755627	0.46338614	0.12547926	154	4	0.030737711	FALSE	24.59482759	PKM	PKM	199.9210526	30.52703703	0	153	0	0.80699543	FALSE	1	PKM	1549458	Infinity	0.03843896
788440	taxon:9606	2.22183709	1280.525111	0.00104158	177668	1902	S-phase kinase associated protein 1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:0031519-&&-PcG protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0097602-&&-cullin family protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:SKP1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05200-&&-Pathways in cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04350-&&-TGF-beta signaling pathway	SKP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKP1	0.507594937	0.450078	0.08138724	154	4	0.02054492	FALSE	17.1011236	SKP1	SKP1	148.7828947	19.98798931	0	153	0	0.79636049	FALSE	1	SKP1	1505314	Infinity	0.03097805
792845	taxon:9606	2.32046636	1226.31473	0.00136643	181272	1902	erb-b2 receptor tyrosine kinase 3	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0021545-&&-cranial nerve development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0014037-&&-Schwann cell differentiation-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0070886-&&-positive regulation of calcineurin-NFAT signaling cascade-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0042060-&&-wound healing-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007507-&&-heart development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051048-&&-negative regulation of secretion-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0055025-&&-positive regulation of cardiac muscle tissue development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0038132-&&-neuregulin binding	G:9606:ERBB3	ERBB3	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	ERBB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBB3	0.493083308	0.43094785	0.06840362	154	4	0.01387114	FALSE	14.89285714	ERBB3	ERBB3	105.8355263	17.80209489	0	153	0	0.77992227	FALSE	1	ERBB3	1775434	Infinity	0.02534329
789180	taxon:9606	2.35465574	791.5224143	4.47E-04	176040	1902	histone cluster 1 H2B family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BF			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BF	0.497364341	0.42469053	0.0280112	154	4	0.01435821	FALSE	5.846153846	HIST1H2BF	HIST1H2BF	104.4285714	6.895974741	0	154	0	0.77422404	FALSE	0	HIST1H2BF	1199536	Infinity	0.02637802
789176	taxon:9606	2.35465574	791.5224143	4.47E-04	176044	1902	histone cluster 1 H2B family member g	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BG			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BG	0.497364341	0.42469053	0.0280112	154	4	0.01435821	FALSE	5.846153846	HIST1H2BG	HIST1H2BG	104.4285714	6.895974741	0	154	0	0.77422404	FALSE	0	HIST1H2BG	1199536	Infinity	0.02637802
789183	taxon:9606	2.35465574	791.5224143	4.47E-04	176037	1902	histone cluster 1 H2B family member i	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BI			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BI	0.497364341	0.42469053	0.0280112	154	4	0.01435821	FALSE	5.846153846	HIST1H2BI	HIST1H2BI	104.4285714	6.895974741	0	154	0	0.77422404	FALSE	0	HIST1H2BI	1199536	Infinity	0.02637802
789184	taxon:9606	2.35465574	791.5224143	4.47E-04	176036	1902	histone cluster 1 H2B family member c	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BC			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BC	0.497364341	0.42469053	0.0280112	154	4	0.01435821	FALSE	5.846153846	HIST1H2BC	HIST1H2BC	104.4285714	6.895974741	0	154	0	0.77422404	FALSE	0	HIST1H2BC	1199536	Infinity	0.02637802
789185	taxon:9606	2.35465574	791.5224143	4.47E-04	176039	1902	histone cluster 1 H2B family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BE			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BE	0.497364341	0.42469053	0.0280112	154	4	0.01435821	FALSE	5.846153846	HIST1H2BE	HIST1H2BE	104.4285714	6.895974741	0	154	0	0.77422404	FALSE	0	HIST1H2BE	1199536	Infinity	0.02637802
789489	taxon:9606	2.31369151	1025.225402	8.34E-04	175355	1902	ISG15 ubiquitin-like modifier	gene	biological_process-&-1&-GO:0019941-&&-modification-dependent protein catabolic process-%%-GO:0032020-&&-ISG15-protein conjugation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0034340-&&-response to type I interferon-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0032649-&&-regulation of interferon-gamma production-%%-GO:0019985-&&-translesion synthesis-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005576-&&-extracellular region-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0005515-&&-protein binding	G:9606:ISG15			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	ISG15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ISG15	0.504561183	0.43220974	0.05373058	154	4	0.020465452	FALSE	10.90909091	ISG15	ISG15	118.1103896	12.71875455	0	154	0	0.78105142	FALSE	0	ISG15	1347876	Infinity	0.0280045
789854	taxon:9606	2.21143847	1587.722643	9.83E-04	174505	1902	stress induced phosphoprotein 1	gene	biological_process-&-1&-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043209-&&-myelin sheath-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005515-&&-protein binding	G:9606:STIP1			KEGG-&-1&-hsa05020-&&-Prion diseases	STIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STIP1	0.508399366	0.45219436	0.09744504	154	4	0.019126054	FALSE	17.29292929	STIP1	STIP1	142.3181818	22.18168882	0	154	0	0.79809359	FALSE	0	STIP1	1509808	Infinity	0.02930502
792066	taxon:9606	2.21679534	2605.225863	0.00108077	182664	1902	complement C1q binding protein	gene	biological_process-&-1&-GO:0039534-&&-negative regulation of MDA-5 signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:1901165-&&-positive regulation of trophoblast cell migration-%%-GO:0006915-&&-apoptotic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0008380-&&-RNA splicing-%%-GO:0042256-&&-mature ribosome assembly-%%-GO:2000510-&&-positive regulation of dendritic cell chemotaxis-%%-GO:0006397-&&-mRNA processing-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006955-&&-immune response-%%-GO:0016032-&&-viral process-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0070131-&&-positive regulation of mitochondrial translation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0030984-&&-kininogen binding-%%-GO:0001849-&&-complement component C1q binding-%%-GO:0005540-&&-hyaluronic acid binding-%%-GO:0031690-&&-adrenergic receptor binding-%%-GO:0097177-&&-mitochondrial ribosome binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:C1QBP			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	C1QBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QBP	0.511805999	0.45110163	0.10101545	153	4	0.026075033	FALSE	19.21904762	C1QBP	C1QBP	172.397351	22.69484162	0	152	0	0.79720078	FALSE	1	C1QBP	1650678	Infinity	0.03570973
788276	taxon:9606	2.21884355	1029.550047	1.61E-04	177960	1902	ribosomal protein S9	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045903-&&-positive regulation of translational fidelity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS9			KEGG-&-1&-hsa03010-&&-Ribosome	RPS9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS9	0.52094836	0.45068522	0.42079463	153	4	0.051362731	FALSE	65.63087248	RPS9	RPS9	230.3267974	77.21448936	0	153	0	0.79685941	FALSE	0	RPS9	601350	Infinity	0.04784384
789427	taxon:9606	2.26500709	931.5513855	3.79E-04	175508	1902	matrin 3	gene	biological_process-&-1&-GO:0010608-&&-posttranscriptional regulation of gene expression|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:MATR3				MATR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MATR3	0.511479592	0.44149972	0.17306843	153	4	0.032696351	FALSE	32.70434783	MATR3	MATR3	184.8211921	37.92553825	0	152	0	0.78916549	FALSE	1	MATR3	808258	Infinity	0.04081448
791238	taxon:9606	2.32314479	1043.9077	3.93E-04	169563	1902	methylphosphate capping enzyme	gene	biological_process-&-1&-GO:0016073-&&-snRNA metabolic process-%%-GO:0040031-&&-snRNA modification-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001510-&&-RNA methylation-%%-GO:0035562-&&-negative regulation of chromatin binding|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008173-&&-RNA methyltransferase activity-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity	G:9606:MEPCE				MEPCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEPCE	0.507273877	0.430451	0.10543743	152	4	0.026660444	FALSE	19.09259259	MEPCE	MEPCE	141.25	22.17376586	0	152	0	0.77947587	FALSE	0	MEPCE	687662	Infinity	0.03381614
787623	taxon:9606	2.32503545	1612.167999	0.00105195	179068	1902	nitric oxide synthase 2	gene	biological_process-&-1&-GO:0032310-&&-prostaglandin secretion-%%-GO:0001912-&&-positive regulation of leukocyte mediated cytotoxicity-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0007623-&&-circadian rhythm-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0072604-&&-interleukin-6 secretion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0006527-&&-arginine catabolic process-%%-GO:0072606-&&-interleukin-8 secretion-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043457-&&-regulation of cellular respiration-%%-GO:0018119-&&-peptidyl-cysteine S-nitrosylation-%%-GO:0009617-&&-response to bacterium-%%-GO:0051712-&&-positive regulation of killing of cells of other organism-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006809-&&-nitric oxide biosynthetic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005622-&&-intracellular-%%-GO:0005777-&&-peroxisome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0034618-&&-arginine binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0034617-&&-tetrahydrobiopterin binding-%%-GO:0010181-&&-FMN binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0050661-&&-NADP binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004517-&&-nitric-oxide synthase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0003958-&&-NADPH-hemoprotein reductase activity-%%-GO:0020037-&&-heme binding	G:9606:NOS2	NOS2	TRUE	KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04146-&&-Peroxisome-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05133-&&-Pertussis-%%-hsa04066-&&-HIF-1 signaling pathway	NOS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOS2	0.510015898	0.43010097	0.09753915	152	4	0.024836166	FALSE	19.85123967	NOS2	NOS2	133.3133333	25.00231427	0	151	0	0.77916076	FALSE	1	NOS2	1788394	Infinity	0.03216803
788044	taxon:9606	2.24326453	864.8296529	2.01E-04	178314	1902	ribosomal protein L3	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0071353-&&-cellular response to interleukin-4|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008097-&&-5S rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL3			KEGG-&-1&-hsa03010-&&-Ribosome	RPL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL3	0.515258593	0.4457789	0.41495295	152	4	0.05016112	FALSE	67.32857143	RPL3	RPL3	223.8684211	75.38677888	0	152	0	0.79278924	FALSE	0	RPL3	597262	Infinity	0.0479581
792354	taxon:9606	2.16842603	1942.813976	0.0011062	182175	1902	conserved helix-loop-helix ubiquitous kinase	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0009636-&&-response to toxic substance-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0033194-&&-response to hydroperoxide-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0010034-&&-response to acetate-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006954-&&-inflammatory response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006955-&&-immune response-%%-GO:0043200-&&-response to amino acid-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0042493-&&-response to drug-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009615-&&-response to virus-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0008384-&&-IkappaB kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:CHUK	CHUK	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	CHUK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHUK	0.513115803	0.46116399	0.11642058	152	4	0.020909298	FALSE	21.66371681	CHUK	CHUK	161.06	28.65639648	0	151	0	0.80526233	FALSE	1	CHUK	1683212	Infinity	0.03136384
788290	taxon:9606	2.26201355	840.6895317	2.31E-04	177947	1902	ribosomal protein S20	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPS20			KEGG-&-1&-hsa03010-&&-Ribosome	RPS20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS20	0.515093128	0.442084	0.39796096	152	4	0.048997279	FALSE	64.53571429	RPS20	RPS20	213.1776316	72.59414498	0	152	0	0.78966441	FALSE	0	RPS20	617286	Infinity	0.04694219
790043	taxon:9606	2.22971483	1562.057717	6.63E-04	174024	1902	WD repeat domain 5	gene	biological_process-&-1&-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0031175-&&-neuron projection development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0001501-&&-skeletal system development-%%-GO:0060271-&&-cilium assembly-%%-GO:0051568-&&-histone H3-K4 methylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036064-&&-ciliary basal body-%%-GO:0071339-&&-MLL1 complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus-%%-GO:0048188-&&-Set1C/COMPASS complex|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)	G:9606:WDR5			KEGG-&-1&-hsa04934-&&-Cushing syndrome	WDR5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR5	0.510990761	0.44848785	0.14961659	152	4	0.027391542	FALSE	24.19417476	WDR5	WDR5	191.3552632	27.95822576	0	152	0	0.79504753	FALSE	0	WDR5	1393826	Infinity	0.04026836
791118	taxon:9606	2.43878998	841.0008808	5.73E-04	169993	1902	leucine rich repeat containing G protein-coupled receptor 4	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045087-&&-innate immune response-%%-GO:0072282-&&-metanephric nephron tubule morphogenesis-%%-GO:0030282-&&-bone mineralization-%%-GO:0061290-&&-canonical Wnt signaling pathway involved in metanephric kidney development-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0030539-&&-male genitalia development-%%-GO:0048565-&&-digestive tract development-%%-GO:0001942-&&-hair follicle development-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0072202-&&-cell differentiation involved in metanephros development-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway-%%-GO:2001013-&&-epithelial cell proliferation involved in renal tubule morphogenesis-%%-GO:0046849-&&-bone remodeling-%%-GO:0007283-&&-spermatogenesis-%%-GO:0072224-&&-metanephric glomerulus development-%%-GO:0036335-&&-intestinal stem cell homeostasis-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0050710-&&-negative regulation of cytokine secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:LGR4			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	LGR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGR4	0.488577521	0.41003941	0.03147107	151	4	0.01633637	FALSE	8.641975309	LGR4	LGR4	90.80536913	9.475808523	0	150	0	0.76020167	FALSE	1	LGR4	800724	Infinity	0.02648683
788286	taxon:9606	2.26059556	968.0976619	2.09E-04	177949	1902	ribosomal protein S18	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS18			KEGG-&-1&-hsa03010-&&-Ribosome	RPS18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS18	0.515921518	0.4423613	0.41395143	151	4	0.049741101	FALSE	65.25352113	RPS18	RPS18	219.9337748	73.72157648	0	151	0	0.78990074	FALSE	0	RPS18	664458	Infinity	0.04825225
790479	taxon:9606	2.56325823	378.5651837	9.13E-04	172735	1902	tectonic family member 3	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:TCTN3				TCTN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCTN3	0.437892438	0.39012847	0.02790287	151	4	0.004844665	FALSE	5.818181818	TCTN3	TCTN3	49.71523179	6.032891929	0	151	0	0.73945696	FALSE	0	TCTN3	1056108	Infinity	0.0188584
791828	taxon:9606	2.19851899	1417.623458	4.81E-04	166657	1902	tubulin alpha 1c	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBA1C			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA1C	0.516087516	0.45485166	0.14684564	150	4	0.030596573	FALSE	25.11666667	TUBA1C	TUBA1C	191.22	30.44328537	0	150	0	0.80024684	FALSE	0	TUBA1C	1020512	Infinity	0.03864457
787799	taxon:9606	2.34394202	1486.163851	5.66E-04	178771	1902	protein kinase AMP-activated non-catalytic subunit beta 1	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0035878-&&-nail development|cellular_component-&-1&-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PRKAB1	PRKAB1	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04921-&&-Oxytocin signaling pathway	PRKAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAB1	0.502191609	0.42663171	0.03337808	150	4	0.013938418	FALSE	5.852272727	PRKAB1	PRKAB1	93.43333333	7.336968429	0	150	0	0.77600966	FALSE	0	PRKAB1	838102	Infinity	0.02317862
788812	taxon:9606	2.16527493	1777.744467	8.08E-04	176820	1902	ubiquitin B	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0019058-&&-viral life cycle-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:1902255-&&-positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0019068-&&-virion assembly-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0047497-&&-mitochondrion transport along microtubule-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1902527-&&-positive regulation of protein monoubiquitination-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0043005-&&-neuron projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UBB			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05012-&&-Parkinson disease-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	UBB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBB	0.512951711	0.46183512	0.08912752	150	4	0.0226005	FALSE	15.9	UBB	UBB	173.0933333	19.70896447	0	150	0	0.80578751	FALSE	0	UBB	1483144	Infinity	0.03359871
791744	taxon:9606	2.23664723	1435.062387	8.84E-04	167087	1902	itchy E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006915-&&-apoptotic process-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0002669-&&-positive regulation of T cell anergy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046642-&&-negative regulation of alpha-beta T cell proliferation-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0090085-&&-regulation of protein deubiquitination-%%-GO:0051607-&&-defense response to virus-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035519-&&-protein K29-linked ubiquitination-%%-GO:0006954-&&-inflammatory response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0045236-&&-CXCR chemokine receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043021-&&-ribonucleoprotein complex binding	G:9606:ITCH			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	ITCH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITCH	0.505515285	0.44709777	0.0751095	149	4	0.01478215	FALSE	15.03333333	ITCH	ITCH	128.2040816	18.51205907	0	148	0	0.79389213	FALSE	1	ITCH	1309788	Infinity	0.02721522
792217	taxon:9606	2.2869072	1256.005921	9.71E-04	182396	1902	ATM serine/threonine kinase	gene	biological_process-&-1&-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007507-&&-heart development-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0033151-&&-V(D)J recombination-%%-GO:0090399-&&-replicative senescence-%%-GO:0000732-&&-strand displacement-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0071500-&&-cellular response to nitrosative stress-%%-GO:1904884-&&-positive regulation of telomerase catalytic core complex assembly-%%-GO:0002331-&&-pre-B cell allelic exclusion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0007140-&&-male meiosis-%%-GO:1904262-&&-negative regulation of TORC1 signaling-%%-GO:0001541-&&-ovarian follicle development-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0048538-&&-thymus development-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0051972-&&-regulation of telomerase activity-%%-GO:0097694-&&-establishment of RNA localization to telomere-%%-GO:0097695-&&-establishment of macromolecular complex localization to telomere-%%-GO:0048599-&&-oocyte development-%%-GO:0007143-&&-female meiotic division-%%-GO:0001756-&&-somitogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0007420-&&-brain development-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0009791-&&-post-embryonic development-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0042159-&&-lipoprotein catabolic process-%%-GO:0045141-&&-meiotic telomere clustering-%%-GO:1904358-&&-positive regulation of telomere maintenance via telomere lengthening-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006260-&&-DNA replication-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0072434-&&-signal transduction involved in mitotic G2 DNA damage checkpoint-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005819-&&-spindle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:1990391-&&-DNA repair complex|molecular_function-&-1&-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004677-&&-DNA-dependent protein kinase activity	G:9606:ATM	ATM	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa03440-&&-Homologous recombination-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance	ATM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATM	0.505037783	0.43727179	0.08042121	149	4	0.016569193	FALSE	17.16853933	ATM	ATM	123.5782313	20.82282241	0	148	0	0.78551547	FALSE	1	ATM	1280714	Infinity	0.02816807
792700	taxon:9606	2.25996534	1835.257122	3.31E-04	181541	1902	DEAH-box helicase 15	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0043279-&&-response to alkaloid-%%-GO:0006397-&&-mRNA processing-%%-GO:0009636-&&-response to toxic substance|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0071008-&&-U2-type post-mRNA release spliceosomal complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding	G:9606:DHX15			KEGG-&-1&-hsa03040-&&-Spliceosome	DHX15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX15	0.514597369	0.44248466	0.18746599	149	4	0.03665752	FALSE	30.65891473	DHX15	DHX15	204.1879195	37.71372343	0	149	0	0.79000578	FALSE	0	DHX15	770464	Infinity	0.04475842
793203	taxon:9606	2.24925161	1398.020423	6.16E-04	180535	1902	protein arginine methyltransferase 1	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0046985-&&-positive regulation of hemoglobin biosynthetic process-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0031175-&&-neuron projection development-%%-GO:0043985-&&-histone H4-R3 methylation-%%-GO:0018216-&&-peptidyl-arginine methylation-%%-GO:0016571-&&-histone methylation-%%-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0008170-&&-N-methyltransferase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0008276-&&-protein methyltransferase activity	G:9606:PRMT1			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04068-&&-FoxO signaling pathway	PRMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT1	0.510828025	0.44459232	0.13763862	149	4	0.032115329	FALSE	27.27619048	PRMT1	PRMT1	200.3129252	30.01138008	0	148	0	0.7917914	FALSE	1	PRMT1	1285652	Infinity	0.04328336
793248	taxon:9606	2.46856783	424.258121	6.13E-04	180454	1902	mitochondrial ribosomal protein L58	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016150-&&-translation release factor activity, codon nonspecific-%%-GO:0004045-&&-aminoacyl-tRNA hydrolase activity	G:9606:MRPL58				MRPL58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL58	0.466008135	0.40509318	0.05931435	149	4	0.011922929	FALSE	8.368421053	MRPL58	MRPL58	78.90604027	9.141871846	0	149	0	0.7552387	FALSE	0	MRPL58	750388	Infinity	0.02433507
789356	taxon:9606	2.23192059	1558.845302	0.00117185	175676	1902	hepatocyte growth factor-regulated tyrosine kinase substrate	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0072657-&&-protein localization to membrane-%%-GO:0016197-&&-endosomal transport-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0010324-&&-membrane invagination-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0043405-&&-regulation of MAP kinase activity|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0033565-&&-ESCRT-0 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005768-&&-endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0032585-&&-multivesicular body membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:HGS			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04145-&&-Phagosome	HGS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HGS	0.503136763	0.44804461	0.05441683	149	4	0.012429871	FALSE	9.909090909	HGS	HGS	114.1812081	11.49384448	0	149	0	0.7946799	FALSE	0	HGS	1460654	Infinity	0.02412901
789698	taxon:9606	2.16023318	1460.587679	3.60E-04	174864	1902	DEAD-box helicase 17	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:2001014-&&-regulation of skeletal muscle cell differentiation-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008186-&&-RNA-dependent ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003723-&&-RNA binding	G:9606:DDX17				DDX17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX17	0.519430052	0.46291299	0.18236884	149	4	0.037988883	FALSE	31.02362205	DDX17	DDX17	239.462585	35.65040221	0	148	0	0.8066278	FALSE	1	DDX17	1040128	Infinity	0.04613923
790804	taxon:9606	2.32078147	1752.137606	8.74E-04	171159	1902	SH3 domain containing kinase binding protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0061024-&&-membrane organization-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0043005-&&-neuron projection-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:SH3KBP1			KEGG-&-1&-hsa04144-&&-Endocytosis	SH3KBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3KBP1	0.499221911	0.43088934	0.06273028	148	4	0.01221545	FALSE	13.48275862	SH3KBP1	SH3KBP1	104.6232877	17.64756634	0	147	0	0.77986975	FALSE	1	SH3KBP1	1132596	Infinity	0.02508786
788074	taxon:9606	2.28265322	599.5564968	2.77E-04	178282	1902	ribosomal protein L31	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL31			KEGG-&-1&-hsa03010-&&-Ribosome	RPL31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL31	0.514432328	0.43808669	0.44447509	148	4	0.050343715	FALSE	67.95035461	RPL31	RPL31	219.5135135	75.86373135	0	148	0	0.78622446	FALSE	0	RPL31	656960	Infinity	0.0496734
789114	taxon:9606	2.36442414	1352.631799	9.76E-04	176169	1902	HECT and RLD domain containing E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032183-&&-SUMO binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:HERC2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HERC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC2	0.495367511	0.42293596	0.03845064	148	4	0.010733537	FALSE	9.5	HERC2	HERC2	89.69863014	10.6746602	0	147	0	0.77259598	FALSE	1	HERC2	1118756	Infinity	0.0229792
789381	taxon:9606	2.28359855	1336.306326	0.00131211	175622	1902	VAMP associated protein A	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0008219-&&-cell death-%%-GO:0044828-&&-negative regulation by host of viral genome replication-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0090114-&&-COPII-coated vesicle budding-%%-GO:0031175-&&-neuron projection development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0044829-&&-positive regulation by host of viral genome replication-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0044791-&&-positive regulation by host of viral release from host cell-%%-GO:0070972-&&-protein localization to endoplasmic reticulum-%%-GO:0061025-&&-membrane fusion|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0031982-&&-vesicle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0033149-&&-FFAT motif binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:VAPA			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	VAPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAPA	0.49598021	0.43790534	0.0739726	148	4	0.01334272	FALSE	13.64864865	VAPA	VAPA	113.630137	17.10233058	0	147	0	0.78606691	FALSE	1	VAPA	1554350	Infinity	0.02580241
789614	taxon:9606	2.25980778	1249.360274	7.69E-04	175052	1902	ring-box 1	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0045116-&&-protein neddylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006513-&&-protein monoubiquitination|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex-%%-GO:0030891-&&-VCB complex-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0019788-&&-NEDD8 transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding	G:9606:RBX1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04350-&&-TGF-beta signaling pathway	RBX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBX1	0.506793049	0.44251551	0.1005196	148	4	0.021475611	FALSE	18.37634409	RBX1	RBX1	148.1232877	22.6620162	0	147	0	0.79003204	FALSE	1	RBX1	1241934	Infinity	0.0324461
788058	taxon:9606	2.32046636	485.4472868	5.54E-05	178296	1902	ribosomal protein L19	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0097421-&&-liver regeneration-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0070180-&&-large ribosomal subunit rRNA binding-%%-GO:1990932-&&-5.8S rRNA binding	G:9606:RPL19			KEGG-&-1&-hsa03010-&&-Ribosome	RPL19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL19	0.511805999	0.43094785	0.47796105	147	4	0.053048495	FALSE	71.3006993	RPL19	RPL19	232.6462585	79.82146036	0	147	0	0.77992227	FALSE	0	RPL19	308186	Infinity	0.05547121
793210	taxon:9606	2.21254136	1625.414717	6.62E-04	180520	1902	DnaJ heat shock protein family (Hsp40) member A1	gene	biological_process-&-1&-GO:1903748-&&-negative regulation of establishment of protein localization to mitochondrion-%%-GO:0051223-&&-regulation of protein transport-%%-GO:1901998-&&-toxin transport-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0007283-&&-spermatogenesis-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0006457-&&-protein folding-%%-GO:1905259-&&-negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0009408-&&-response to heat|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0098554-&&-cytoplasmic side of endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005524-&&-ATP binding	G:9606:DNAJA1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA1	0.51393784	0.45196895	0.11201193	147	4	0.027226489	FALSE	19.22321429	DNAJA1	DNAJA1	188.8231293	22.44278659	0	147	0	0.79790977	FALSE	0	DNAJA1	1312414	Infinity	0.03880179
793358	taxon:9606	2.2040334	2097.586251	5.16E-04	180240	1902	heterogeneous nuclear ribonucleoprotein C (C1/C2)	gene	biological_process-&-1&-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0008380-&&-RNA splicing-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:HNRNPC			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPC	0.517085751	0.45371363	0.16503831	147	4	0.036114339	FALSE	28.296	HNRNPC	HNRNPC	225	33.36607989	0	146	0	0.79932777	FALSE	1	HNRNPC	1130376	Infinity	0.0457475
787893	taxon:9606	2.26989129	1477.178205	7.78E-04	178651	1902	proteasome 26S subunit, ATPase 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0001824-&&-blastocyst development-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0000932-&&-P-body-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:PSMC3			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC3	0.510178117	0.44054973	0.15112665	146	4	0.017435119	FALSE	28.36363636	PSMC3	PSMC3	137.9166667	34.81694932	0	145	0	0.78835145	FALSE	1	PSMC3	1168092	Infinity	0.03058914
788054	taxon:9606	2.31652749	644.2201518	1.27E-04	178300	1902	ribosomal protein L15	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045471-&&-response to ethanol-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031672-&&-A band-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL15			KEGG-&-1&-hsa03010-&&-Ribosome	RPL15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL15	0.512951711	0.43168061	0.47557865	146	4	0.050129279	FALSE	71.25	RPL15	RPL15	217.3287671	79.81390648	0	146	0	0.78057875	FALSE	0	RPL15	426964	Infinity	0.05164657
792526	taxon:9606	2.27556326	1511.975205	0.00179923	181849	1902	calnexin	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0009306-&&-protein secretion-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0007568-&&-aging-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0072583-&&-clathrin-dependent endocytosis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0043197-&&-dendritic spine-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0030424-&&-axon-%%-GO:0005840-&&-ribosome-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0044233-&&-ER-mitochondrion membrane contact site-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CANX			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CANX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CANX	0.504878816	0.43945164	0.09418989	146	4	0.020437805	FALSE	16.94565217	CANX	CANX	147.7671233	21.34596888	0	146	0	0.78740612	FALSE	0	CANX	2295324	Infinity	0.03312678
788048	taxon:9606	2.31069797	469.6887069	1.76E-04	178305	1902	ribosomal protein L9	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005840-&&-ribosome|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding	G:9606:RPL9			KEGG-&-1&-hsa03010-&&-Ribosome	RPL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL9	0.509368053	0.43276967	0.46149425	145	4	0.048613504	FALSE	73.8828125	RPL9	RPL9	217.9034483	79.30783195	0	145	0	0.78155034	FALSE	0	RPL9	493962	Infinity	0.05134948
788540	taxon:9606	2.24090121	1706.79422	7.25E-04	177474	1902	spectrin alpha, non-erythrocytic 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007411-&&-axon guidance-%%-GO:0051693-&&-actin filament capping-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0035580-&&-specific granule lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0008091-&&-spectrin-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:SPTAN1			KEGG-&-1&-hsa04210-&&-Apoptosis	SPTAN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPTAN1	0.511969358	0.44624903	0.11197318	145	4	0.028094795	FALSE	19.58558559	SPTAN1	SPTAN1	190.0068966	23.33432144	0	145	0	0.79318313	FALSE	0	SPTAN1	1338604	Infinity	0.04047005
788902	taxon:9606	2.31904837	1543.650816	5.94E-04	176644	1902	splicing factor 1	gene	biological_process-&-1&-GO:0033327-&&-Leydig cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0030575-&&-nuclear body organization-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0030238-&&-male sex determination-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0050810-&&-regulation of steroid biosynthetic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005840-&&-ribosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0045131-&&-pre-mRNA branch point binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:SF1				SF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF1	0.508238276	0.43121136	0.10203881	145	4	0.024071302	FALSE	19.47524752	SF1	SF1	149.2027972	22.88363616	0	144	0	0.78015861	FALSE	1	SF1	1002778	Infinity	0.03557044
793309	taxon:9606	2.47487002	1297.007929	2.12E-04	163949	1902	ring finger and CCCH-type domains 1	gene	biological_process-&-1&-GO:0050856-&&-regulation of T cell receptor signaling pathway-%%-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0048535-&&-lymph node development-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0045623-&&-negative regulation of T-helper cell differentiation-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0048536-&&-spleen development-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0061470-&&-T follicular helper cell differentiation-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0002635-&&-negative regulation of germinal center formation-%%-GO:0042098-&&-T cell proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0001782-&&-B cell homeostasis|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0010494-&&-cytoplasmic stress granule|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:RC3H1				RC3H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RC3H1	0.493842365	0.40406162	0.10210728	145	4	0.027373342	FALSE	18.71818182	RC3H1	RC3H1	117.062069	20.79605312	0	145	0	0.75418833	FALSE	0	RC3H1	409246	Infinity	0.03634883
791636	taxon:9606	2.39688042	1028.96896	5.72E-04	167709	1902	Nanog homeobox	gene	biological_process-&-1&-GO:0001714-&&-endodermal cell fate specification-%%-GO:0030154-&&-cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:NANOG			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	NANOG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NANOG	0.493842365	0.41720897	0.03785836	144	4	0.013065362	FALSE	8.883116883	NANOG	NANOG	94.95774648	10.18857481	0	143	0	0.7671866	FALSE	1	NANOG	932062	Infinity	0.02562186
792232	taxon:9606	2.18496928	1333.786269	6.69E-04	182372	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	gene	biological_process-&-1&-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0009790-&&-embryo development-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0045261-&&-proton-transporting ATP synthase complex, catalytic core F(1)-%%-GO:0016020-&&-membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0022857-&&-transmembrane transporter activity	G:9606:ATP5A1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5A1	0.511479592	0.45767234	0.14224353	144	4	0.030074367	FALSE	24.51851852	ATP5A1	ATP5A1	207.9929578	28.92438053	0	143	0	0.80250512	FALSE	1	ATP5A1	1335050	Infinity	0.04126026
792363	taxon:9606	2.26847329	1061.718343	6.85E-04	182159	1902	adaptor related protein complex 2 mu 1 subunit	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030122-&&-AP-2 adaptor complex|molecular_function-&-1&-GO:0005048-&&-signal sequence binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0008289-&&-lipid binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0044325-&&-ion channel binding	G:9606:AP2M1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2M1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2M1	0.507273877	0.44082511	0.1000899	144	4	0.018641513	FALSE	18.85057471	AP2M1	AP2M1	137.1690141	21.83727395	0	143	0	0.78858778	FALSE	1	AP2M1	1035504	Infinity	0.03044086
788424	taxon:9606	2.20639672	1366.815996	3.21E-04	177692	1902	serine and arginine rich splicing factor 1	gene	biological_process-&-1&-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0097421-&&-liver regeneration-%%-GO:0000395-&&-mRNA 5'-splice site recognition-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0050733-&&-RS domain binding	G:9606:SRSF1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa03040-&&-Spliceosome	SRSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF1	0.517586318	0.45322765	0.22065728	144	4	0.034301344	FALSE	35.44628099	SRSF1	SRSF1	216.6549296	42.61349246	0	143	0	0.79893388	FALSE	1	SRSF1	835216	Infinity	0.04419725
792822	taxon:9606	2.22057665	1716.308426	0.00125789	181311	1902	enolase 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009615-&&-response to virus-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000015-&&-phosphopyruvate hydratase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004634-&&-phosphopyruvate hydratase activity	G:9606:ENO1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa03018-&&-RNA degradation	ENO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENO1	0.510015898	0.45033348	0.12121212	144	4	0.025664231	FALSE	20.16504854	ENO1	ENO1	179.9791667	26.16224815	0	144	0	0.79657056	FALSE	0	ENO1	1822152	Infinity	0.03744596
793014	taxon:9606	2.35969749	1071.560362	9.10E-04	180892	1902	G protein-coupled receptor kinase 5	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0007217-&&-tachykinin receptor signaling pathway-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0047696-&&-beta-adrenergic receptor kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:GRK5			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway	GRK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK5	0.499688474	0.42378313	0.04934572	144	4	0.017888134	FALSE	11.54444444	GRK5	GRK5	109.3309859	13.29867677	0	143	0	0.77338375	FALSE	1	GRK5	1140750	Infinity	0.02776972
789876	taxon:9606	2.32991965	1827.381759	2.84E-04	174462	1902	splicing factor 3a subunit 1	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005686-&&-U2 snRNP-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SF3A1			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3A1	0.513444302	0.42919935	0.19706682	144	4	0.03238387	FALSE	31.02380952	SF3A1	SF3A1	190.6944444	38.19401549	0	144	0	0.77834673	FALSE	0	SF3A1	678404	Infinity	0.04611548
791158	taxon:9606	2.29415472	1748.253625	6.55E-04	169863	1902	pre-mRNA processing factor 40 homolog A	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF40A			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF40A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF40A	0.508883249	0.43589039	0.13991895	143	4	0.026249174	FALSE	25.76851852	PRPF40A	PRPF40A	162.5390071	30.63868328	0	142	0	0.78430755	FALSE	1	PRPF40A	1000224	Infinity	0.03735551
787184	taxon:9606	2.26563731	1072.657648	0.00135723	179911	1902	SMAD family member 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030902-&&-hindbrain development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0060348-&&-bone development-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0051216-&&-cartilage development-%%-GO:0030901-&&-midbrain development-%%-GO:0006954-&&-inflammatory response-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0042592-&&-homeostatic process-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0031053-&&-primary miRNA processing-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0002051-&&-osteoblast fate commitment-%%-GO:0001710-&&-mesodermal cell fate commitment-%%-GO:0007276-&&-gamete generation-%%-GO:0001657-&&-ureteric bud development-%%-GO:0007165-&&-signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005622-&&-intracellular-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0070878-&&-primary miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0070410-&&-co-SMAD binding	G:9606:SMAD1	SMAD1	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD1	0.499844188	0.44137691	0.07477204	143	4	0.01188896	FALSE	14.5	SMAD1	SMAD1	113.822695	16.76758536	0	142	0	0.78906045	FALSE	1	SMAD1	1537974	Infinity	0.02508453
788056	taxon:9606	2.25129983	661.2544124	1.86E-04	178302	1902	ribosomal protein L12	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding	G:9606:RPL12			KEGG-&-1&-hsa03010-&&-Ribosome	RPL12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL12	0.514762516	0.44418784	0.45237861	143	4	0.048052445	FALSE	69.35606061	RPL12	RPL12	218.5384615	75.33077317	0	143	0	0.79145003	FALSE	0	RPL12	525332	Infinity	0.04728072
788079	taxon:9606	2.33275563	928.830189	2.19E-04	178275	1902	ribosomal protein L37a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RPL37A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL37A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL37A	0.50969177	0.42867756	0.40736728	143	4	0.044811863	FALSE	61.60150376	RPL37A	RPL37A	194.006993	68.41287987	0	143	0	0.77787406	FALSE	0	RPL37A	496984	Infinity	0.04716242
792398	taxon:9606	2.31936348	1619.852286	4.47E-04	182092	1902	cryptochrome circadian clock 2	gene	biological_process-&-1&-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:2000118-&&-regulation of sodium-dependent phosphate transport-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0000719-&&-photoreactive repair-%%-GO:0007623-&&-circadian rhythm-%%-GO:0009785-&&-blue light signaling pathway-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003914-&&-DNA (6-4) photolyase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0071949-&&-FAD binding-%%-GO:0003904-&&-deoxyribodipyrimidine photo-lyase activity-%%-GO:0009882-&&-blue light photoreceptor activity	G:9606:CRY2			KEGG-&-1&-hsa04710-&&-Circadian rhythm	CRY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRY2	0.511969358	0.43115277	0.08399189	143	4	0.024716927	FALSE	14.76923077	CRY2	CRY2	142.4184397	18.67040292	0	142	0	0.78010609	FALSE	1	CRY2	806032	Infinity	0.03391348
788720	taxon:9606	2.20151253	1677.440671	0.00117383	177121	1902	heat shock protein 90 beta family member 1	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0031247-&&-actin rod assembly-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0015031-&&-protein transport-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0051208-&&-sequestering of calcium ion-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0002224-&&-toll-like receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0046790-&&-virion binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:HSP90B1	HSP90B1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSP90B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90B1	0.511316544	0.45423316	0.10233029	143	4	0.024404783	FALSE	20.09375	HSP90B1	HSP90B1	181.7234043	24.42292019	0	142	0	0.79974791	FALSE	1	HSP90B1	1774656	Infinity	0.03685354
788801	taxon:9606	2.27839924	972.6228008	5.93E-04	176846	1902	Tu translation elongation factor, mitochondrial	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0005515-&&-protein binding	G:9606:TUFM				TUFM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUFM	0.505993691	0.43890464	0.16517286	143	4	0.033414956	FALSE	29.0952381	TUFM	TUFM	191.2167832	31.38431619	0	143	0	0.78693346	FALSE	0	TUFM	1057964	Infinity	0.04297343
793363	taxon:9606	2.20623917	1477.586271	4.96E-04	180238	1902	heterogeneous nuclear ribonucleoprotein F	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:HNRNPF				HNRNPF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPF	0.515589842	0.45326002	0.17295381	143	4	0.034557972	FALSE	28.97413793	HNRNPF	HNRNPF	220.3006993	33.56700714	0	143	0	0.79896014	FALSE	0	HNRNPF	1119250	Infinity	0.04488319
787582	taxon:9606	2.25240271	329.6308981	2.30E-04	179147	1902	ribosomal protein L10a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045471-&&-response to ethanol-%%-GO:0006412-&&-translation-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL10A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL10A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL10A	0.514267393	0.44397034	0.47907302	142	4	0.049393065	FALSE	73.4296875	RPL10A	RPL10A	233.084507	78.90880737	0	142	0	0.79126622	FALSE	0	RPL10A	518852	Infinity	0.05043875
787625	taxon:9606	2.24468253	1257.755485	5.08E-04	179070	1902	non-POU domain containing, octamer-binding	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006310-&&-DNA recombination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0007623-&&-circadian rhythm-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0042382-&&-paraspeckles-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding	G:9606:NONO				NONO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NONO	0.51360871	0.4454973	0.12055498	142	4	0.029061999	FALSE	22.48571429	NONO	NONO	197.0571429	25.5203528	0	141	0	0.79255291	FALSE	1	NONO	1040254	Infinity	0.04221294
788100	taxon:9606	2.1824484	1927.500334	0.00104229	178243	1902	prohibitin	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0045745-&&-positive regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0016575-&&-histone deacetylation-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:0045917-&&-positive regulation of complement activation-%%-GO:0050821-&&-protein stabilization-%%-GO:0007165-&&-signal transduction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0001850-&&-complement component C3a binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001851-&&-complement component C3b binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0031871-&&-proteinase activated receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:PHB				PHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHB	0.512296391	0.45820098	0.11752786	141	4	0.025770692	FALSE	19.33980583	PHB	PHB	190.106383	23.82175772	0	141	0	0.80292527	FALSE	0	PHB	1607348	Infinity	0.03762571
788261	taxon:9606	2.23995588	1725.897186	6.37E-04	177977	1902	ribophorin I	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity-%%-GO:0005515-&&-protein binding	G:9606:RPN1			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPN1	0.511969358	0.44643736	0.14042553	141	4	0.023435375	FALSE	20.57281553	RPN1	RPN1	174.4893617	26.52426744	0	141	0	0.79334069	FALSE	0	RPN1	1215506	Infinity	0.037154
788294	taxon:9606	2.34346936	566.7364451	1.04E-04	177942	1902	ribosomal protein S24	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0015935-&&-small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS24			KEGG-&-1&-hsa03010-&&-Ribosome	RPS24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS24	0.508399366	0.42671776	0.45055724	141	4	0.045934889	FALSE	67.2248062	RPS24	RPS24	199.893617	72.85179834	0	141	0	0.77608844	FALSE	0	RPS24	323510	Infinity	0.04920889
792579	taxon:9606	2.23948322	1051.183852	5.57E-04	181781	1902	chaperonin containing TCP1 subunit 6A	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0071987-&&-WD40-repeat domain binding	G:9606:CCT6A				CCT6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT6A	0.512132822	0.44653159	0.15714286	141	4	0.02669714	FALSE	24.94285714	CCT6A	CCT6A	187.248227	29.04425711	0	141	0	0.79341946	FALSE	0	CCT6A	1218410	Infinity	0.03981162
788607	taxon:9606	2.20450607	1075.050593	4.96E-04	177348	1902	t-complex 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0007021-&&-tubulin complex assembly-%%-GO:1901998-&&-toxin transport-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0044053-&&-translocation of peptides or proteins into host cell cytoplasm-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0090666-&&-scaRNA localization to Cajal body-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:2000109-&&-regulation of macrophage apoptotic process-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005829-&&-cytosol-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TCP1				TCP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCP1	0.512296391	0.45361635	0.15481256	141	4	0.028172361	FALSE	24.41904762	TCP1	TCP1	198.0780142	28.31969745	0	141	0	0.79924899	FALSE	0	TCP1	1206360	Infinity	0.04027613
792130	taxon:9606	2.23286592	1217.760529	0.00110681	182544	1902	actin, alpha 1, skeletal muscle	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043503-&&-skeletal muscle fiber adaptation-%%-GO:0010226-&&-response to lithium ion-%%-GO:0090131-&&-mesenchyme migration-%%-GO:0009991-&&-response to extracellular stimulus-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0016049-&&-cell growth-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0048741-&&-skeletal muscle fiber development|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0072562-&&-blood microparticle-%%-GO:0030175-&&-filopodium-%%-GO:0005865-&&-striated muscle thin filament-%%-GO:0001725-&&-stress fiber-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0044297-&&-cell body-%%-GO:0030017-&&-sarcomere-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0017022-&&-myosin binding-%%-GO:0043531-&&-ADP binding	G:9606:ACTA1				ACTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTA1	0.507434356	0.44785493	0.07267534	140	4	0.016263342	FALSE	14.54761905	ACTA1	ACTA1	138.7028986	16.80247007	0	139	0	0.79452235	FALSE	1	ACTA1	1398658	Infinity	0.02924687
788068	taxon:9606	2.39278399	716.5070567	9.43E-05	178285	1902	ribosomal protein L27a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL27A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL27A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL27A	0.50297899	0.41792322	0.44737924	140	4	0.047353357	FALSE	65.34090909	RPL27A	RPL27A	209.1928571	71.87623146	0	140	0	0.76786933	FALSE	0	RPL27A	342318	Infinity	0.05582752
788064	taxon:9606	2.30927997	434.1923379	1.33E-04	178295	1902	ribosomal protein L21	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL21			KEGG-&-1&-hsa03010-&&-Ribosome	RPL21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL21	0.511969358	0.43303541	0.48591984	140	4	0.046913434	FALSE	72.30232558	RPL21	RPL21	210.9642857	78.79064015	0	140	0	0.78178667	FALSE	0	RPL21	415596	Infinity	0.04942763
788114	taxon:9606	2.28879786	1375.500111	9.90E-04	178213	1902	protein tyrosine phosphatase, non-receptor type 11	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0035265-&&-organ growth-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0048839-&&-inner ear development-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0048609-&&-multicellular organismal reproductive process-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0021697-&&-cerebellar cortex formation-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0031295-&&-T cell costimulation-%%-GO:0060325-&&-face morphogenesis-%%-GO:0030168-&&-platelet activation-%%-GO:0046887-&&-positive regulation of hormone secretion-%%-GO:0007420-&&-brain development-%%-GO:0033277-&&-abortive mitotic cell cycle-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0061582-&&-intestinal epithelial cell migration-%%-GO:0030220-&&-platelet formation-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0048806-&&-genitalia development-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0051463-&&-negative regulation of cortisol secretion-%%-GO:0007411-&&-axon guidance-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0060125-&&-negative regulation of growth hormone secretion-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0032528-&&-microvillus organization-%%-GO:0007507-&&-heart development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:PTPN11			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04360-&&-Axon guidance-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	PTPN11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN11	0.49598021	0.43691058	0.10705596	140	4	0.010244062	FALSE	18.20512821	PTPN11	PTPN11	113.1811594	23.08871336	0	139	0	0.78520036	FALSE	1	PTPN11	1289194	Infinity	0.0258357
792315	taxon:9606	2.22057665	1485.236663	8.50E-04	182240	1902	cofilin 1	gene	biological_process-&-1&-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0014823-&&-response to activity-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0021766-&&-hippocampus development-%%-GO:0010593-&&-negative regulation of lamellipodium assembly-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0097107-&&-postsynaptic density assembly-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:2000784-&&-positive regulation of establishment of cell polarity regulating cell shape-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0030042-&&-actin filament depolymerization-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051511-&&-negative regulation of unidimensional cell growth-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0071362-&&-cellular response to ether-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:1904377-&&-positive regulation of protein localization to cell periphery-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:1902951-&&-negative regulation of dendritic spine maintenance-%%-GO:0030030-&&-cell projection organization-%%-GO:1904783-&&-positive regulation of NMDA glutamate receptor activity-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0009615-&&-response to virus-%%-GO:2000814-&&-positive regulation of barbed-end actin filament capping|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:1902936-&&-phosphatidylinositol bisphosphate binding	G:9606:CFL1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05133-&&-Pertussis	CFL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFL1	0.508399366	0.45033348	0.12230216	140	4	0.022569599	FALSE	19.17171717	CFL1	CFL1	172.2642857	22.76679454	0	140	0	0.79657056	FALSE	0	CFL1	1421468	Infinity	0.0357662
788420	taxon:9606	2.20812983	1645.021424	6.70E-04	177700	1902	SET nuclear proto-oncogene	gene	biological_process-&-1&-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0006260-&&-DNA replication-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0016032-&&-viral process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0019888-&&-protein phosphatase regulator activity	G:9606:SET	SET	TRUE		SET	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SET	0.513444302	0.45287192	0.1326563	140	4	0.027596479	FALSE	21.97247706	SET	SET	200.7536232	25.52832651	0	139	0	0.79864503	FALSE	1	SET	1296640	Infinity	0.04101591
790287	taxon:9606	2.43500867	1241.477494	5.83E-04	173417	1902	chromobox 5	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0016605-&&-PML body-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0010369-&&-chromocenter-%%-GO:0005634-&&-nucleus-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005721-&&-pericentric heterochromatin|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:CBX5				CBX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX5	0.492628993	0.41067616	0.16449804	140	4	0.023024695	FALSE	28.94117647	CBX5	CBX5	143.9710145	34.09252525	0	139	0	0.76083189	FALSE	1	CBX5	1039626	Infinity	0.04133889
791495	taxon:9606	2.30077202	948.7425847	8.06E-04	168384	1902	MMS19 homolog, cytosolic iron-sulfur assembly component	gene	biological_process-&-1&-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0009725-&&-response to hormone-%%-GO:0000160-&&-phosphorelay signal transduction system-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0016226-&&-iron-sulfur cluster assembly|cellular_component-&-1&-GO:0005675-&&-holo TFIIH complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0071817-&&-MMXD complex-%%-GO:0097361-&&-CIA complex|molecular_function-&-1&-GO:0030331-&&-estrogen receptor binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0019899-&&-enzyme binding	G:9606:MMS19				MMS19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMS19	0.497672975	0.43463672	0.05108956	139	4	0.010830051	FALSE	7.790322581	MMS19	MMS19	110.2805755	8.661295204	0	139	0	0.78320466	FALSE	0	MMS19	1045976	Infinity	0.02553565
787809	taxon:9606	2.21931621	736.6134667	0.0013665	178756	1902	protein kinase C delta	gene	biological_process-&-1&-GO:0032079-&&-positive regulation of endodeoxyribonuclease activity-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation-%%-GO:0071447-&&-cellular response to hydroperoxide-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0032613-&&-interleukin-10 production-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0007049-&&-cell cycle-%%-GO:1900163-&&-positive regulation of phospholipid scramblase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0030168-&&-platelet activation-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0007165-&&-signal transduction-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0016572-&&-histone phosphorylation-%%-GO:1904385-&&-cellular response to angiotensin-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0023021-&&-termination of signal transduction-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:2000753-&&-positive regulation of glucosylceramide catabolic process-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0090398-&&-cellular senescence-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:2000755-&&-positive regulation of sphingomyelin catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0051490-&&-negative regulation of filopodium assembly-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0042119-&&-neutrophil activation-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0032615-&&-interleukin-12 production-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016363-&&-nuclear matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004699-&&-calcium-independent protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019900-&&-kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0043560-&&-insulin receptor substrate binding	G:9606:PRKCD			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04140-&&-Autophagy - animal-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	PRKCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCD	0.503294634	0.45058924	0.07546157	139	4	0.014312198	FALSE	15.90666667	PRKCD	PRKCD	129.6934307	17.35595005	0	138	0	0.79678063	FALSE	1	PRKCD	1558762	Infinity	0.02689269
788062	taxon:9606	2.27572081	767.1190068	1.36E-04	178293	1902	ribosomal protein L22	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL22			KEGG-&-1&-hsa03010-&&-Ribosome	RPL22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL22	0.512460064	0.43942121	0.46095298	139	4	0.047314808	FALSE	65.99253731	RPL22	RPL22	224.7625899	71.7626589	0	139	0	0.78737986	FALSE	0	RPL22	467892	Infinity	0.05020384
788293	taxon:9606	2.33133764	441.8298894	1.24E-04	177943	1902	ribosomal protein S23	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPS23			KEGG-&-1&-hsa03010-&&-Ribosome	RPS23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS23	0.50969177	0.4289383	0.47023251	139	4	0.044734098	FALSE	68.890625	RPS23	RPS23	193.2805755	74.89460933	0	139	0	0.77811039	FALSE	0	RPS23	383904	Infinity	0.04683319
788721	taxon:9606	2.35008666	1095.410113	8.80E-04	177120	1902	TNF receptor associated factor 1	gene	biological_process-&-1&-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0006461-&&-protein complex assembly-%%-GO:2001236-&&-regulation of extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding	G:9606:TRAF1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05222-&&-Small cell lung cancer	TRAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF1	0.497981993	0.42551622	0.06966509	139	4	0.01223199	FALSE	14.51948052	TRAF1	TRAF1	101.2408759	16.99805766	0	138	0	0.77498556	FALSE	1	TRAF1	1130218	Infinity	0.02532814
788799	taxon:9606	2.19930676	1722.793334	0.00120648	176850	1902	tubulin alpha 4a	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:TUBA4A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA4A	0.514762516	0.45468873	0.11479512	139	4	0.026669426	FALSE	19.03669725	TUBA4A	TUBA4A	185.9208633	22.4169491	0	139	0	0.80011554	FALSE	0	TUBA4A	1678902	Infinity	0.037563
787889	taxon:9606	2.28139278	1640.374691	3.53E-04	178652	1902	proteasome 26S subunit, ATPase 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005737-&&-cytoplasm-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC2			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC2	0.511479592	0.43832873	0.2124183	138	4	0.020446004	FALSE	32.39285714	PSMC2	PSMC2	157.7352941	42.8906749	0	137	0	0.78643454	FALSE	1	PSMC2	750404	Infinity	0.03554502
792813	taxon:9606	2.2256184	2887.600373	6.11E-04	181324	1902	emerin	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0007517-&&-muscle organ development-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0006936-&&-muscle contraction-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:EMD			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	EMD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EMD	0.51393784	0.44931332	0.09694989	138	4	0.024402536	FALSE	17.25	EMD	EMD	180.1985294	21.32244795	0	137	0	0.79573027	FALSE	1	EMD	1193206	Infinity	0.03758681
788706	taxon:9606	2.29825114	1518.424395	3.83E-04	177145	1902	tumor protein p53 binding protein 1	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0002039-&&-p53 binding	G:9606:TP53BP1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	TP53BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53BP1	0.509044748	0.43511346	0.139744	138	4	0.025358278	FALSE	21.66055046	TP53BP1	TP53BP1	177.8550725	25.36670734	0	138	0	0.78362481	FALSE	0	TP53BP1	842762	Infinity	0.04105109
789548	taxon:9606	2.28879786	984.9305618	7.04E-04	175210	1902	histone deacetylase 4	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006476-&&-protein deacetylation-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0007399-&&-nervous system development-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030183-&&-B cell differentiation-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002076-&&-osteoblast development-%%-GO:0042113-&&-B cell activation-%%-GO:0001501-&&-skeletal system development-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0071374-&&-cellular response to parathyroid hormone stimulus-%%-GO:0006954-&&-inflammatory response-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0048742-&&-regulation of skeletal muscle fiber development-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation|cellular_component-&-1&-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031672-&&-A band-%%-GO:0005634-&&-nucleus-%%-GO:0042641-&&-actomyosin-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0043234-&&-protein complex-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0001025-&&-RNA polymerase III transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0044212-&&-transcription regulatory region DNA binding	G:9606:HDAC4			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis	HDAC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC4	0.500311915	0.43691058	0.10283224	138	4	0.017943978	FALSE	19.80681818	HDAC4	HDAC4	142.1691177	22.58476184	0	137	0	0.78520036	FALSE	1	HDAC4	1081704	Infinity	0.03232652
789720	taxon:9606	2.21285647	1091.242512	3.91E-04	174824	1902	chaperonin containing TCP1 subunit 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1901998-&&-toxin transport-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0090666-&&-scaRNA localization to Cajal body-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0042470-&&-melanosome-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CCT4				CCT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT4	0.514102564	0.45190459	0.16132445	138	4	0.028353836	FALSE	24.21296296	CCT4	CCT4	202.6376812	28.19564019	0	138	0	0.79785726	FALSE	0	CCT4	1117532	Infinity	0.04161793
787971	taxon:9606	2.37624074	816.243292	6.52E-04	178480	1902	pericentriolar material 1	gene	biological_process-&-1&-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0001764-&&-neuron migration-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0051297-&&-centrosome organization-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0060271-&&-cilium assembly-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0022027-&&-interkinetic nuclear migration-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0035176-&&-social behavior-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0097730-&&-non-motile cilium-%%-GO:0036064-&&-ciliary basal body-%%-GO:0031965-&&-nuclear membrane-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0034451-&&-centriolar satellite-%%-GO:0005813-&&-centrosome-%%-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0000242-&&-pericentriolar material|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding	G:9606:PCM1				PCM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCM1	0.489322758	0.42083278	0.0943538	137	4	0.010263597	FALSE	13.56716418	PCM1	PCM1	102.919708	16.19443499	0	137	0	0.77062654	FALSE	0	PCM1	907232	Infinity	0.02675766
788788	taxon:9606	2.33448873	2101.947241	8.79E-04	176902	1902	RAB7A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:0061724-&&-lipophagy-%%-GO:0048524-&&-positive regulation of viral process-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:0022615-&&-protein to membrane docking-%%-GO:0006897-&&-endocytosis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1902583-&&-multi-organism intracellular transport-%%-GO:1905366-&&-negative regulation of intralumenal vesicle formation-%%-GO:1903542-&&-negative regulation of exosomal secretion-%%-GO:0090382-&&-phagosome maturation-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0090385-&&-phagosome-lysosome fusion-%%-GO:0007174-&&-epidermal growth factor catabolic process-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0015031-&&-protein transport-%%-GO:0019076-&&-viral release from host cell-%%-GO:0006622-&&-protein targeting to lysosome|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0032419-&&-extrinsic component of lysosome membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0030904-&&-retromer complex-%%-GO:0033162-&&-melanosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0005770-&&-late endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019003-&&-GDP binding-%%-GO:1905394-&&-retromer complex binding-%%-GO:0005525-&&-GTP binding	G:9606:RAB7A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04140-&&-Autophagy - animal-%%-hsa05132-&&-Salmonella infection-%%-hsa04145-&&-Phagosome-%%-hsa05146-&&-Amoebiasis-%%-hsa05152-&&-Tuberculosis-%%-hsa04137-&&-Mitophagy - animal	RAB7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB7A	0.496748219	0.42835932	0.07428081	137	4	0.013568506	FALSE	11.93902439	RAB7A	RAB7A	118.0218978	15.39458802	0	137	0	0.77758521	FALSE	0	RAB7A	1184846	Infinity	0.02878929
788828	taxon:9606	2.21458957	1194.802794	0.00111654	176803	1902	ubiquitin protein ligase E3A	gene	biological_process-&-1&-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0006508-&&-proteolysis-%%-GO:0007420-&&-brain development-%%-GO:0060736-&&-prostate gland growth-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035037-&&-sperm entry-%%-GO:0016032-&&-viral process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2000058-&&-regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000502-&&-proteasome complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:UBE3A			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	UBE3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE3A	0.506793049	0.45155094	0.06633499	137	4	0.01525359	FALSE	13.9382716	UBE3A	UBE3A	137.2888889	15.79488492	0	136	0	0.79756841	FALSE	1	UBE3A	1434066	Infinity	0.02826438
789574	taxon:9606	2.35733417	1436.522962	7.43E-04	175149	1902	SET domain bifurcated 1	gene	biological_process-&-1&-GO:0045471-&&-response to ethanol-%%-GO:0033273-&&-response to vitamin-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0090309-&&-positive regulation of methylation-dependent chromatin silencing|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:SETDB1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa00310-&&-Lysine degradation	SETDB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETDB1	0.493234932	0.42420799	0.10079433	137	4	0.019262904	FALSE	17.56179775	SETDB1	SETDB1	142.0145985	19.78720422	0	137	0	0.77377764	FALSE	0	SETDB1	1182268	Infinity	0.0358638
787614	taxon:9606	2.40680637	1415.507452	2.35E-04	179097	1902	SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0007338-&&-single fertilization-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0001651-&&-dense fibrillar component-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0034512-&&-box C/D snoRNA binding-%%-GO:0030621-&&-U4 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030622-&&-U4atac snRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0034511-&&-U3 snoRNA binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0051117-&&-ATPase binding	G:9606:SNU13			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03040-&&-Spliceosome	SNU13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNU13	0.501563477	0.41548835	0.18325665	136	4	0.030469729	FALSE	29.95495495	SNU13	SNU13	155.4253731	34.30186671	0	135	0	0.76553227	FALSE	1	SNU13	479606	Infinity	0.04249874
788291	taxon:9606	2.2520876	463.6407888	1.19E-04	177941	1902	ribosomal protein S25	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005840-&&-ribosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS25			KEGG-&-1&-hsa03010-&&-Ribosome	RPS25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS25	0.51328	0.44403246	0.50784314	136	4	0.047411781	FALSE	70.59848485	RPS25	RPS25	229.7205882	77.82495541	0	136	0	0.79131873	FALSE	0	RPS25	421550	Infinity	0.04972148
789080	taxon:9606	2.37592563	1127.653071	6.88E-04	176228	1902	TSC22 domain family member 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TSC22D1				TSC22D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC22D1	0.492780338	0.42088859	0.0323196	136	4	0.011100783	FALSE	7.117647059	TSC22D1	TSC22D1	92.34328358	8.15659365	0	135	0	0.77067906	FALSE	1	TSC22D1	888280	Infinity	0.02405033
787226	taxon:9606	2.28501654	1342.673249	3.36E-04	179835	1902	minichromosome maintenance complex component 3	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005658-&&-alpha DNA polymerase:primase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003678-&&-DNA helicase activity	G:9606:MCM3			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM3	0.509206349	0.43763359	0.16130459	135	4	0.029413544	FALSE	23.40384615	MCM3	MCM3	204.3703704	25.81754489	0	135	0	0.78583058	FALSE	0	MCM3	852324	Infinity	0.04626737
787919	taxon:9606	2.20939026	1101.502318	0.0011358	178608	1902	protein tyrosine kinase 2	gene	biological_process-&-1&-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0045087-&&-innate immune response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0046621-&&-negative regulation of organ growth-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0038007-&&-netrin-activated signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0010594-&&-regulation of endothelial cell migration-%%-GO:0051964-&&-negative regulation of synapse assembly-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:0007411-&&-axon guidance-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001890-&&-placenta development-%%-GO:0040023-&&-establishment of nucleus localization-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:1900024-&&-regulation of substrate adhesion-dependent cell spreading-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0021955-&&-central nervous system neuron axonogenesis-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0001570-&&-vasculogenesis-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007172-&&-signal complex assembly-%%-GO:0009790-&&-embryo development-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001764-&&-neuron migration-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0048870-&&-cell motility-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003779-&&-actin binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0008432-&&-JUN kinase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0042169-&&-SH2 domain binding	G:9606:PTK2	PTK2	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer	PTK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTK2	0.504243948	0.45261356	0.10628845	135	4	0.011963051	FALSE	18.96202532	PTK2	PTK2	132.9548872	22.82393514	0	134	0	0.79843496	FALSE	1	PTK2	1391272	Infinity	0.02720773
788211	taxon:9606	2.32676855	881.7197379	0.00106476	178069	1902	REL proto-oncogene, NF-kB subunit	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0034097-&&-response to cytokine-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0006954-&&-inflammatory response-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:REL			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05203-&&-Viral carcinogenesis	REL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REL	0.493842365	0.42978061	0.0414673	135	4	0.010239243	FALSE	10.98333333	REL	REL	99.02255639	11.72492318	0	134	0	0.77887191	FALSE	1	REL	1234554	Infinity	0.02392295
788590	taxon:9606	2.35150465	606.266312	6.13E-04	177385	1902	TATA-box binding protein	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0016032-&&-viral process-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001939-&&-female pronucleus-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005672-&&-transcription factor TFIIA complex-%%-GO:0001940-&&-male pronucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001034-&&-RNA polymerase III transcription factor activity, sequence-specific DNA binding	G:9606:TBP			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	TBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBP	0.490220049	0.42525963	0.101162	135	4	0.012182446	FALSE	16.76923077	TBP	TBP	115.3308271	18.51038212	0	134	0	0.77474923	FALSE	1	TBP	865262	Infinity	0.02868365
789190	taxon:9606	2.35244998	969.4182368	4.40E-04	176034	1902	histone cluster 2 H2B family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2BE			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H2BE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2BE	0.503136763	0.42508874	0.21304588	135	4	0.02869493	FALSE	32.63366337	HIST2H2BE	HIST2H2BE	185.2592593	37.50236122	0	135	0	0.77459167	FALSE	0	HIST2H2BE	908826	Infinity	0.0462764
790167	taxon:9606	2.24153143	1371.402063	2.63E-04	173725	1902	small nuclear ribonucleoprotein U5 subunit 200	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0000354-&&-cis assembly of pre-catalytic spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005682-&&-U5 snRNP-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0042802-&&-identical protein binding	G:9606:SNRNP200			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRNP200	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRNP200	0.515258593	0.44612357	0.2028936	135	4	0.033372518	FALSE	30.35897436	SNRNP200	SNRNP200	225.0526316	34.52115378	0	134	0	0.79307809	FALSE	1	SNRNP200	697976	Infinity	0.04792433
790605	taxon:9606	2.29620293	1025.832498	0.00211182	171799	1902	ubiquilin 1	gene	biological_process-&-1&-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1901340-&&-negative regulation of store-operated calcium channel activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0035973-&&-aggrephagy-%%-GO:0034140-&&-negative regulation of toll-like receptor 3 signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1902175-&&-regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005829-&&-cytosol-%%-GO:0016235-&&-aggresome-%%-GO:0043234-&&-protein complex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBQLN1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UBQLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBQLN1	0.498136646	0.43550158	0.06511682	134	4	0.012202438	FALSE	14.48648649	UBQLN1	UBQLN1	109.5378788	16.60797313	0	133	0	0.78396618	FALSE	1	UBQLN1	2122506	Infinity	0.02528871
791198	taxon:9606	2.41767764	990.550669	6.74E-04	169752	1902	ligand dependent nuclear receptor interacting factor 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0005515-&&-protein binding	G:9606:LRIF1				LRIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRIF1	0.484885127	0.41362007	0.05123757	134	4	0.013609907	FALSE	11.68055556	LRIF1	LRIF1	113.5227273	12.90563183	0	133	0	0.76372039	FALSE	1	LRIF1	1058736	Infinity	0.03157304
788057	taxon:9606	2.32314479	664.6618738	1.38E-04	178297	1902	ribosomal protein L18a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0097327-&&-response to antineoplastic agent-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL18A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL18A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL18A	0.510502864	0.430451	0.46324767	134	4	0.043512516	FALSE	65.128	RPL18A	RPL18A	203.5373134	70.49465766	0	134	0	0.77947587	FALSE	0	RPL18A	362338	Infinity	0.04853861
788196	taxon:9606	2.37655585	668.6833541	3.64E-04	178096	1902	RB binding protein 7, chromatin remodeling factor	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0008283-&&-cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0048545-&&-response to steroid hormone-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0016575-&&-histone deacetylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity	G:9606:RBBP7				RBBP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP7	0.494451295	0.42077698	0.19279542	134	4	0.023530543	FALSE	29.62921348	RBBP7	RBBP7	166.0447761	32.63923201	0	134	0	0.77057402	FALSE	0	RBBP7	799262	Infinity	0.04297225
789007	taxon:9606	2.4244525	785.7599914	4.70E-04	176400	1902	gigaxonin	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:GAN				GAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAN	0.494908979	0.41246426	0.07344437	134	4	0.023238337	FALSE	14.53191489	GAN	GAN	123.7424242	16.12728673	0	133	0	0.76259125	FALSE	1	GAN	762616	Infinity	0.03489038
788174	taxon:9606	2.28706476	1414.416396	4.87E-04	178125	1902	RAN, member RAS oncogene family	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0021766-&&-hippocampus development-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0071389-&&-cellular response to mineralocorticoid stimulus-%%-GO:0051301-&&-cell division-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0071806-&&-protein transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0035281-&&-pre-miRNA export from nucleus-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0000055-&&-ribosomal large subunit export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000056-&&-ribosomal small subunit export from nucleus-%%-GO:1902570-&&-protein localization to nucleolus-%%-GO:0007286-&&-spermatid development-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0042470-&&-melanosome-%%-GO:0002177-&&-manchette-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0055037-&&-recycling endosome-%%-GO:0000785-&&-chromatin-%%-GO:0030496-&&-midbody-%%-GO:0042565-&&-RNA nuclear export complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0005643-&&-nuclear pore-%%-GO:0036126-&&-sperm flagellum-%%-GO:0090543-&&-Flemming body-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0061676-&&-importin-alpha family protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0090631-&&-pre-miRNA transporter activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019003-&&-GDP binding	G:9606:RAN			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa03013-&&-RNA transport	RAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAN	0.505993691	0.43724166	0.09101585	133	4	0.024124766	FALSE	16.35789474	RAN	RAN	177.0610687	18.88640634	0	132	0	0.78548921	FALSE	1	RAN	962258	Infinity	0.04022334
792336	taxon:9606	2.30864976	1616.217146	5.38E-04	182211	1902	chromodomain helicase DNA binding protein 3	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0051297-&&-centrosome organization-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007051-&&-spindle organization-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006333-&&-chromatin assembly or disassembly|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016581-&&-NuRD complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004386-&&-helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0003723-&&-RNA binding	G:9606:CHD3				CHD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD3	0.505674653	0.43315362	0.11955373	133	4	0.02044593	FALSE	19.51020408	CHD3	CHD3	157.8396947	23.25257164	0	132	0	0.78189171	FALSE	1	CHD3	938610	Infinity	0.03690758
792632	taxon:9606	2.1890657	2317.101303	5.97E-04	181681	1902	eukaryotic translation elongation factor 1 delta	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0045296-&&-cadherin binding	G:9606:EEF1D			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	EEF1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1D	0.515093128	0.45681589	0.10428655	133	4	0.025493985	FALSE	17.17117117	EEF1D	EEF1D	190.9770992	21.64627809	0	132	0	0.80182238	FALSE	1	EEF1D	1074178	Infinity	0.03804173
788658	taxon:9606	2.3565464	1152.516845	9.95E-04	177243	1902	transforming growth factor beta receptor 1	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060978-&&-angiogenesis involved in coronary vascular morphogenesis-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:1905075-&&-positive regulation of occluding junction disassembly-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0008354-&&-germ cell migration-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0043062-&&-extracellular structure organization-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0001822-&&-kidney development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0001824-&&-blastocyst development-%%-GO:0008584-&&-male gonad development-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0060037-&&-pharyngeal system development-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0009791-&&-post-embryonic development-%%-GO:0042060-&&-wound healing-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0060017-&&-parathyroid gland development-%%-GO:0060043-&&-regulation of cardiac muscle cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048538-&&-thymus development-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0070723-&&-response to cholesterol-%%-GO:0060021-&&-palate development-%%-GO:0003342-&&-proepicardium development-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0001501-&&-skeletal system development-%%-GO:1905223-&&-epicardium morphogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0048870-&&-cell motility-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0007507-&&-heart development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005768-&&-endosome-%%-GO:0043235-&&-receptor complex-%%-GO:0009986-&&-cell surface-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0070022-&&-transforming growth factor beta receptor complex|molecular_function-&-1&-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005025-&&-transforming growth factor beta receptor activity, type I-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0004672-&&-protein kinase activity	G:9606:TGFBR1			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TGFBR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBR1	0.48962149	0.4243498	0.0610687	133	4	0.009762427	FALSE	12.17567568	TGFBR1	TGFBR1	93.84732824	14.26162332	0	132	0	0.77390893	FALSE	1	TGFBR1	1082310	Infinity	0.02369537
788677	taxon:9606	2.29210651	1001.382009	8.36E-04	177212	1902	transketolase	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0005999-&&-xylulose biosynthetic process-%%-GO:0046166-&&-glyceraldehyde-3-phosphate biosynthetic process-%%-GO:0009052-&&-pentose-phosphate shunt, non-oxidative branch-%%-GO:0040008-&&-regulation of growth|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0004802-&&-transketolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0048037-&&-cofactor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:TKT	TKT	TRUE	KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00030-&&-Pentose phosphate pathway	TKT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TKT	0.502348888	0.4362799	0.13247211	133	4	0.016275316	FALSE	20.30120482	TKT	TKT	140.610687	24.93017009	0	132	0	0.78464892	FALSE	1	TKT	1178540	Infinity	0.03206455
789966	taxon:9606	2.27745392	1813.305795	5.97E-04	174221	1902	prohibitin 2	gene	biological_process-&-1&-GO:1902808-&&-positive regulation of cell cycle G1/S phase transition-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050821-&&-protein stabilization-%%-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0031536-&&-positive regulation of exit from mitosis-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0033218-&&-amide binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0030331-&&-estrogen receptor binding	G:9606:PHB2				PHB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHB2	0.508721852	0.43908682	0.09273183	133	4	0.020312568	FALSE	14.47311828	PHB2	PHB2	160.7067669	17.76219843	0	133	0	0.78709101	FALSE	0	PHB2	1072090	Infinity	0.03599725
790322	taxon:9606	2.39656531	559.2489343	0.00106236	173319	1902	protection of telomeres 1	gene	biological_process-&-1&-GO:0016233-&&-telomere capping-%%-GO:1905774-&&-regulation of DNA helicase activity-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0060383-&&-positive regulation of DNA strand elongation-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:1905776-&&-positive regulation of DNA helicase activity-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0032202-&&-telomere assembly|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0070187-&&-shelterin complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000783-&&-nuclear telomere cap complex|molecular_function-&-1&-GO:0061821-&&-telomeric D-loop binding-%%-GO:0010521-&&-telomerase inhibitor activity-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0017151-&&-DEAD/H-box RNA helicase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:1990955-&&-G-rich single-stranded DNA binding-%%-GO:0043047-&&-single-stranded telomeric DNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding	G:9606:POT1				POT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POT1	0.485031751	0.41726382	0.04439225	133	4	0.012936773	FALSE	10.1641791	POT1	POT1	92.61832061	11.18347733	0	132	0	0.76723912	FALSE	1	POT1	1198936	Infinity	0.02498752
787424	taxon:9606	2.26768552	1279.677574	6.52E-04	179456	1902	lactate dehydrogenase A	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0048569-&&-post-embryonic animal organ development-%%-GO:0006096-&&-glycolytic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007584-&&-response to nutrient-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0009749-&&-response to glucose-%%-GO:0051591-&&-response to cAMP-%%-GO:0043627-&&-response to estrogen-%%-GO:0019674-&&-NAD metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006089-&&-lactate metabolic process-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004459-&&-L-lactate dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0051287-&&-NAD binding	G:9606:LDHA			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	LDHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHA	0.505037783	0.44097825	0.12474657	132	4	0.021713238	FALSE	19.82022472	LDHA	LDHA	172.1923077	24.49214225	0	131	0	0.78871908	FALSE	1	LDHA	1121180	Infinity	0.03801994
788059	taxon:9606	2.305026	433.6657989	1.15E-04	178299	1902	ribosomal protein L17	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL17			KEGG-&-1&-hsa03010-&&-Ribosome	RPL17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL17	0.508077289	0.43383459	0.47443905	132	4	0.045566753	FALSE	65.72357724	RPL17	RPL17	227.1439394	70.17194985	0	132	0	0.78249567	FALSE	0	RPL17	425522	Infinity	0.05291031
788080	taxon:9606	2.36206082	910.1968061	1.63E-04	178274	1902	ribosomal protein L38	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0001501-&&-skeletal system development-%%-GO:0006417-&&-regulation of translation-%%-GO:0048318-&&-axial mesoderm development-%%-GO:0034463-&&-90S preribosome assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0001503-&&-ossification-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0007605-&&-sensory perception of sound|cellular_component-&-1&-GO:0033291-&&-eukaryotic 80S initiation complex-%%-GO:0005829-&&-cytosol-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL38			KEGG-&-1&-hsa03010-&&-Ribosome	RPL38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL38	0.501877347	0.42335912	0.37635901	132	4	0.038282361	FALSE	54.27731092	RPL38	RPL38	186.0227273	58.03001801	0	132	0	0.77298986	FALSE	0	RPL38	434976	Infinity	0.0471421
792571	taxon:9606	2.32582322	1080.278903	5.81E-04	181795	1902	cyclin B1	gene	biological_process-&-1&-GO:0042246-&&-tissue regeneration-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0090266-&&-regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0001556-&&-oocyte maturation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0071283-&&-cellular response to iron(III) ion-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0060623-&&-regulation of chromosome condensation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0051987-&&-positive regulation of attachment of spindle microtubules to kinetochore-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:2000775-&&-histone H3-S10 phosphorylation involved in chromosome condensation-%%-GO:0046680-&&-response to DDT-%%-GO:0048565-&&-digestive tract development-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0035173-&&-histone kinase activity-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005113-&&-patched binding	G:9606:CCNB1	CCNB1	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CCNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNB1	0.501877347	0.42995529	0.0832755	132	4	0.014869616	FALSE	13.20253165	CCNB1	CCNB1	126.1742424	15.0714899	0	132	0	0.77902946	FALSE	0	CCNB1	899516	Infinity	0.03027939
788944	taxon:9606	2.32976209	1117.199844	2.19E-04	176555	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016584-&&-nucleosome positioning-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0043596-&&-nuclear replication fork-%%-GO:0001650-&&-fibrillar center-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016589-&&-NURF complex-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0031213-&&-RSF complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0031491-&&-nucleosome binding	G:9606:SMARCA5				SMARCA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA5	0.507273877	0.42922838	0.20655933	132	4	0.031431999	FALSE	31.26785714	SMARCA5	SMARCA5	216.5307692	35.36724727	0	131	0	0.77837298	FALSE	1	SMARCA5	650060	Infinity	0.05216167
793213	taxon:9606	2.23617457	1148.160725	6.30E-04	180517	1902	heat shock protein family A (Hsp70) member 1 like	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042026-&&-protein refolding-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0044297-&&-cell body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:HSPA1L			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPA1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA1L	0.510665393	0.44719228	0.10363174	132	4	0.023128843	FALSE	16.8989899	HSPA1L	HSPA1L	173.3636364	19.8505988	0	132	0	0.7939709	FALSE	0	HSPA1L	1098502	Infinity	0.03674789
791961	taxon:9606	2.23286592	1055.482317	3.50E-04	182806	1902	solute carrier family 25 member 5	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0006810-&&-transport-%%-GO:0015867-&&-ATP transport-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0016032-&&-viral process-%%-GO:0015866-&&-ADP transport-%%-GO:1901029-&&-negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0007059-&&-chromosome segregation|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0071817-&&-MMXD complex|molecular_function-&-1&-GO:0015207-&&-adenine transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005471-&&-ATP:ADP antiporter activity-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:SLC25A5			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa04217-&&-Necroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SLC25A5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A5	0.512951711	0.44785493	0.21456254	131	4	0.036441404	FALSE	31.40707965	SLC25A5	SLC25A5	220.3587786	33.26762824	0	131	0	0.79452235	FALSE	0	SLC25A5	861678	Infinity	0.04639948
792397	taxon:9606	2.35638885	1195.370682	3.23E-04	182093	1902	cryptochrome circadian clock 1	gene	biological_process-&-1&-GO:0033762-&&-response to glucagon-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032868-&&-response to insulin-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0009785-&&-blue light signaling pathway-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019915-&&-lipid storage-%%-GO:2000850-&&-negative regulation of glucocorticoid secretion-%%-GO:0006094-&&-gluconeogenesis|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003914-&&-DNA (6-4) photolyase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003904-&&-deoxyribodipyrimidine photo-lyase activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0009882-&&-blue light photoreceptor activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:CRY1			KEGG-&-1&-hsa04710-&&-Circadian rhythm	CRY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRY1	0.506953224	0.42437818	0.09035853	131	4	0.023459606	FALSE	14.39622642	CRY1	CRY1	145.503876	16.67596457	0	130	0	0.77393519	FALSE	1	CRY1	620774	Infinity	0.03654763
792633	taxon:9606	2.21143847	1668.616218	7.13E-04	181680	1902	eukaryotic translation elongation factor 1 gamma	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0009615-&&-response to virus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0045296-&&-cadherin binding	G:9606:EEF1G			KEGG-&-1&-hsa05134-&&-Legionellosis	EEF1G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1G	0.511153601	0.45219436	0.10780039	131	4	0.026416771	FALSE	18.75257732	EEF1G	EEF1G	195.372093	22.07042499	0	130	0	0.79809359	FALSE	1	EEF1G	1170850	Infinity	0.0399634
789142	taxon:9606	2.33511895	799.5945091	2.21E-04	176120	1902	mitogen-activated protein kinase kinase kinase 14	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0031295-&&-T cell costimulation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006955-&&-immune response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K14			KEGG-&-1&-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	MAP3K14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K14	0.50140669	0.42824371	0.22395833	131	4	0.03192826	FALSE	34.69724771	MAP3K14	MAP3K14	166.6589147	37.31005274	0	130	0	0.77748017	FALSE	1	MAP3K14	467904	Infinity	0.04052989
789719	taxon:9606	2.20040964	1120.922291	5.28E-04	174825	1902	chaperonin containing TCP1 subunit 7	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005874-&&-microtubule-%%-GO:0005739-&&-mitochondrion-%%-GO:0044297-&&-cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CCT7				CCT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT7	0.512132822	0.45446083	0.1475044	131	4	0.023793679	FALSE	22.02105263	CCT7	CCT7	190.480916	25.09750658	0	131	0	0.79993173	FALSE	0	CCT7	1142888	Infinity	0.03848568
789889	taxon:9606	2.28281078	1053.807311	2.99E-04	174423	1902	pre-mRNA processing factor 8	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006397-&&-mRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0071356-&&-cellular response to tumor necrosis factor|cellular_component-&-1&-GO:0005682-&&-U5 snRNP-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0017070-&&-U6 snRNA binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0030623-&&-U5 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF8	PRPF8	TRUE	KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF8	0.511316544	0.43805646	0.21729651	131	4	0.031518195	FALSE	32.08035714	PRPF8	PRPF8	203.7674419	37.28888548	0	130	0	0.7861982	FALSE	1	PRPF8	650304	Infinity	0.04593146
790085	taxon:9606	2.41184812	760.5226879	1.67E-04	173912	1902	ribosomal protein L35	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL35			KEGG-&-1&-hsa03010-&&-Ribosome	RPL35	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL35	0.50125	0.41461981	0.45437463	131	4	0.043745261	FALSE	62.16129032	RPL35	RPL35	204.5114504	66.73029262	0	131	0	0.76469198	FALSE	0	RPL35	396474	Infinity	0.05635056
790931	taxon:9606	2.28722231	1438.436522	4.67E-04	170679	1902	LUC7 like 2, pre-mRNA splicing factor	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection|cellular_component-&-1&-GO:0071004-&&-U2-type prespliceosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:LUC7L2				LUC7L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUC7L2	0.506953224	0.43721155	0.12561516	130	4	0.02162217	FALSE	20.13829787	LUC7L2	LUC7L2	153.34375	23.2833392	0	129	0	0.78546295	FALSE	1	LUC7L2	773542	Infinity	0.03475252
787386	taxon:9606	2.28848275	1347.2572	4.55E-04	179518	1902	myosin IC	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0051028-&&-mRNA transport-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:1900078-&&-positive regulation of cellular response to insulin stimulus-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:1900748-&&-positive regulation of vascular endothelial growth factor signaling pathway-%%-GO:0006605-&&-protein targeting-%%-GO:0038089-&&-positive regulation of cell migration by vascular endothelial growth factor signaling pathway-%%-GO:0030838-&&-positive regulation of actin filament polymerization|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0060171-&&-stereocilium membrane-%%-GO:0001725-&&-stress fiber-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0031941-&&-filamentous actin-%%-GO:0045160-&&-myosin I complex-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0016461-&&-unconventional myosin complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding	G:9606:MYO1C				MYO1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO1C	0.504243948	0.43697074	0.11568277	130	4	0.016951695	FALSE	15.84705882	MYO1C	MYO1C	142.6076923	18.37656794	0	130	0	0.78525288	FALSE	0	MYO1C	794936	Infinity	0.03240772
787954	taxon:9606	2.27981724	1469.972187	4.47E-04	178519	1902	p21 (RAC1) activated kinase 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:2001271-&&-negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0040008-&&-regulation of growth-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016032-&&-viral process-%%-GO:0060996-&&-dendritic spine development-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PAK2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04660-&&-T cell receptor signaling pathway	PAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK2	0.507916403	0.43863165	0.08144685	130	4	0.01783615	FALSE	13.7826087	PAK2	PAK2	147.3984375	16.32497972	0	129	0	0.78669713	FALSE	1	PAK2	865588	Infinity	0.03308824
792284	taxon:9606	2.22656373	979.5652807	9.69E-04	182285	1902	cyclin dependent kinase 4	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0051301-&&-cell division-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0050994-&&-regulation of lipid catabolic process-%%-GO:0010288-&&-response to lead ion-%%-GO:0046890-&&-regulation of lipid biosynthetic process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0060612-&&-adipose tissue development-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0055093-&&-response to hyperoxia-%%-GO:1904628-&&-cellular response to phorbol 13-acetate 12-myristate-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0010033-&&-response to organic substance-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0045727-&&-positive regulation of translation-%%-GO:1904637-&&-cellular response to ionomycin-%%-GO:0042493-&&-response to drug-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0033574-&&-response to testosterone-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071353-&&-cellular response to interleukin-4|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0000785-&&-chromatin-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097129-&&-cyclin D2-CDK4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0032403-&&-protein complex binding	G:9606:CDK4	CDK4	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04530-&&-Tight junction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05214-&&-Glioma-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma	CDK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK4	0.506632975	0.44912256	0.07608825	130	4	0.015923565	FALSE	12.51948052	CDK4	CDK4	144.8769231	14.1404344	0	130	0	0.79557271	FALSE	0	CDK4	1255416	Infinity	0.03026455
788303	taxon:9606	2.39467465	497.3190474	8.88E-04	177920	1902	retinoid X receptor alpha	gene	biological_process-&-1&-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0060687-&&-regulation of branching involved in prostate gland morphogenesis-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0043010-&&-camera-type eye development-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0006766-&&-vitamin metabolic process-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0001893-&&-maternal placenta development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007566-&&-embryo implantation-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0045994-&&-positive regulation of translational initiation by iron-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0070644-&&-vitamin D response element binding-%%-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0004886-&&-9-cis retinoic acid receptor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0044323-&&-retinoic acid-responsive element binding-%%-GO:0019899-&&-enzyme binding	G:9606:RXRA	RXRA	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05160-&&-Hepatitis C-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04976-&&-Bile secretion-%%-hsa05226-&&-Gastric cancer	RXRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RXRA	0.479665072	0.41759326	0.09510335	130	4	0.009582357	FALSE	16.09836066	RXRA	RXRA	100.2265625	17.29061808	0	129	0	0.76755423	FALSE	1	RXRA	1046298	Infinity	0.02683233
788678	taxon:9606	2.33874271	493.1685686	0.0010445	177215	1902	thymidine kinase 1	gene	biological_process-&-1&-GO:0009165-&&-nucleotide biosynthetic process-%%-GO:0009157-&&-deoxyribonucleoside monophosphate biosynthetic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0043097-&&-pyrimidine nucleoside salvage-%%-GO:0046104-&&-thymidine metabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006259-&&-DNA metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019206-&&-nucleoside kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004797-&&-thymidine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TK1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	TK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TK1	0.487686227	0.42758017	0.03297244	130	4	0.009903917	FALSE	8.711538462	TK1	TK1	93.6328125	9.095668412	0	129	0	0.77687621	FALSE	1	TK1	1298382	Infinity	0.02298608
789647	taxon:9606	2.20592406	1381.364026	3.37E-04	174982	1902	tubulin beta 4B class IVb	gene	biological_process-&-1&-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0007017-&&-microtubule-based process-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003924-&&-GTPase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0005525-&&-GTP binding	G:9606:TUBB4B			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB4B	0.515258593	0.45332476	0.15074538	130	4	0.031886451	FALSE	20.98245614	TUBB4B	TUBB4B	234.3692308	24.80189256	0	130	0	0.79901266	FALSE	0	TUBB4B	920744	Infinity	0.04764571
790078	taxon:9606	2.31400662	927.6042855	2.60E-04	173930	1902	SPT16 homolog, facilitates chromatin remodeling subunit	gene	biological_process-&-1&-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006260-&&-DNA replication-%%-GO:0034724-&&-DNA replication-independent nucleosome organization-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0035101-&&-FACT complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0005515-&&-protein binding	G:9606:SUPT16H				SUPT16H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT16H	0.5071135	0.43215088	0.15538878	130	4	0.026828211	FALSE	23.04081633	SUPT16H	SUPT16H	194.28125	26.14045022	0	129	0	0.7809989	FALSE	1	SUPT16H	681302	Infinity	0.04572399
787876	taxon:9606	2.28627698	1382.517276	3.60E-04	178666	1902	proteasome subunit alpha 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005839-&&-proteasome core complex-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005829-&&-cytosol-%%-GO:0030017-&&-sarcomere-%%-GO:0030016-&&-myofibril-%%-GO:0005844-&&-polysome-%%-GO:0000502-&&-proteasome complex-%%-GO:0000932-&&-P-body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004298-&&-threonine-type endopeptidase activity-%%-GO:0035639-&&-purine ribonucleoside triphosphate binding	G:9606:PSMA6			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA6	0.510502864	0.43739232	0.22553295	129	4	0.02156724	FALSE	30.98165138	PSMA6	PSMA6	169.9457364	40.67062939	0	129	0	0.7856205	FALSE	0	PSMA6	727644	Infinity	0.03849105
788086	taxon:9606	2.31180085	542.0979554	1.40E-04	178266	1902	ribosomal protein lateral stalk subunit P2	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPLP2			KEGG-&-1&-hsa03010-&&-Ribosome	RPLP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPLP2	0.507755619	0.43256321	0.47644044	129	4	0.043276522	FALSE	64.90909091	RPLP2	RPLP2	215.1811024	68.75988219	0	128	0	0.78136652	FALSE	1	RPLP2	383626	Infinity	0.0505695
792268	taxon:9606	2.28281078	827.9863443	6.33E-04	182312	1902	cell division cycle 20	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0090129-&&-positive regulation of synapse maturation-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007049-&&-cell cycle-%%-GO:0050773-&&-regulation of dendrite development-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005819-&&-spindle-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0010997-&&-anaphase-promoting complex binding	G:9606:CDC20			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	CDC20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC20	0.50471995	0.43805646	0.12048494	129	4	0.017404299	FALSE	19.06097561	CDC20	CDC20	144.976378	21.88147683	0	128	0	0.7861982	FALSE	1	CDC20	1023648	Infinity	0.03265437
788167	taxon:9606	2.32409012	1583.615557	4.63E-04	178139	1902	RAD23 homolog A, nucleotide excision repair protein	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:RAD23A			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RAD23A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD23A	0.501877347	0.43027591	0.15348081	129	4	0.016086619	FALSE	25.37755102	RAD23A	RAD23A	132.488189	31.36213838	0	128	0	0.77931831	FALSE	1	RAD23A	710980	Infinity	0.03175274
788357	taxon:9606	2.41878053	1654.275694	0.00110686	177809	1902	syndecan binding protein	gene	biological_process-&-1&-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903553-&&-positive regulation of extracellular exosome assembly-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0002091-&&-negative regulation of receptor internalization-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0042327-&&-positive regulation of phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005895-&&-interleukin-5 receptor complex-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016020-&&-membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005912-&&-adherens junction-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005137-&&-interleukin-5 receptor binding-%%-GO:0045545-&&-syndecan binding-%%-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:SDCBP				SDCBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDCBP	0.483569491	0.41343147	0.03324584	129	4	0.008506747	FALSE	7.65625	SDCBP	SDCBP	85.68503937	9.275597048	0	128	0	0.76353658	FALSE	1	SDCBP	1242328	Infinity	0.023955
789296	taxon:9606	2.36852056	1127.945158	6.32E-04	175797	1902	mediator complex subunit 23	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:MED23				MED23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED23	0.491873658	0.42220448	0.09823159	129	4	0.009611457	FALSE	11.17391304	MED23	MED23	100.1860465	13.58908907	0	129	0	0.77191324	FALSE	0	MED23	812244	Infinity	0.0257448
788070	taxon:9606	2.39908618	480.0121463	6.80E-05	178287	1902	ribosomal protein L27	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL27			KEGG-&-1&-hsa03010-&&-Ribosome	RPL27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL27	0.50471995	0.41682538	0.5136565	128	4	0.044672582	FALSE	66.76	RPL27	RPL27	210.6015625	72.60097021	0	128	0	0.76681897	FALSE	0	RPL27	254244	Infinity	0.05659601
792846	taxon:9606	2.26910351	1378.224557	4.93E-04	181275	1902	epidermal growth factor receptor pathway substrate 15	gene	biological_process-&-1&-GO:0032456-&&-endocytic recycling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0061024-&&-membrane organization-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0016050-&&-vesicle organization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0048268-&&-clathrin coat assembly-%%-GO:0015031-&&-protein transport-%%-GO:0019065-&&-receptor-mediated endocytosis of virus by host cell-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0006895-&&-Golgi to endosome transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0060170-&&-ciliary membrane-%%-GO:0016235-&&-aggresome-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0045296-&&-cadherin binding	G:9606:EPS15			KEGG-&-1&-hsa04144-&&-Endocytosis	EPS15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPS15	0.504085481	0.44070268	0.11593651	128	4	0.01917919	FALSE	17.43333333	EPS15	EPS15	165.7777778	20.90546886	0	127	0	0.78848275	FALSE	1	EPS15	952766	Infinity	0.03664407
789927	taxon:9606	2.1991492	866.7052614	3.59E-04	174337	1902	chaperonin containing TCP1 subunit 8	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050821-&&-protein stabilization-%%-GO:0046931-&&-pore complex assembly-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005929-&&-cilium-%%-GO:0005576-&&-extracellular region-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005813-&&-centrosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0044297-&&-cell body-%%-GO:0045111-&&-intermediate filament cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding	G:9606:CCT8				CCT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT8	0.512296391	0.45472131	0.17593504	128	4	0.027027784	FALSE	24.85858586	CCT8	CCT8	216.1640625	27.8505177	0	128	0	0.8001418	FALSE	0	CCT8	985804	Infinity	0.04352881
790312	taxon:9606	2.36442414	534.2945135	8.19E-05	173348	1902	ribosomal protein L36	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL36			KEGG-&-1&-hsa03010-&&-Ribosome	RPL36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL36	0.501877347	0.42293596	0.47170276	128	4	0.04317271	FALSE	63.16666667	RPL36	RPL36	214.4921875	67.45897411	0	128	0	0.77259598	FALSE	0	RPL36	321084	Infinity	0.05466162
787403	taxon:9606	2.23491413	1212.869949	5.94E-04	179491	1902	nucleosome assembly protein 1 like 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006260-&&-DNA replication-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NAP1L1				NAP1L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAP1L1	0.508238276	0.44744448	0.13574194	127	4	0.027548386	FALSE	22.39784946	NAP1L1	NAP1L1	202.16	24.24787158	0	126	0	0.79418098	FALSE	1	NAP1L1	1044562	Infinity	0.04263067
787427	taxon:9606	2.31668505	1163.481751	4.42E-04	179454	1902	lactate dehydrogenase B	gene	biological_process-&-1&-GO:0006089-&&-lactate metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0019674-&&-NAD metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0045121-&&-membrane raft-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004459-&&-L-lactate dehydrogenase activity-%%-GO:0019900-&&-kinase binding	G:9606:LDHB			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00640-&&-Propanoate metabolism	LDHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHB	0.502034429	0.43165125	0.12464516	127	4	0.018804144	FALSE	18.65116279	LDHB	LDHB	154.24	23.37681291	0	126	0	0.78055249	FALSE	1	LDHB	805076	Infinity	0.03647682
788292	taxon:9606	2.32030881	408.0603103	9.62E-05	177940	1902	ribosomal protein S26	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPS26			KEGG-&-1&-hsa03010-&&-Ribosome	RPS26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS26	0.506313131	0.43097712	0.47556555	127	4	0.041999593	FALSE	63.22881356	RPS26	RPS26	208.8346457	67.82733414	0	127	0	0.77994853	FALSE	0	RPS26	363948	Infinity	0.0496516
792622	taxon:9606	2.30880731	933.1567161	6.67E-04	181701	1902	epithelial cell transforming 2	gene	biological_process-&-1&-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0015031-&&-protein transport-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0000910-&&-cytokinesis-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030496-&&-midbody-%%-GO:0097149-&&-centralspindlin complex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017048-&&-Rho GTPase binding	G:9606:ECT2				ECT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECT2	0.501877347	0.43312406	0.03912011	127	4	0.012955761	FALSE	6.830985915	ECT2	ECT2	113.3070866	7.497574198	0	127	0	0.78186545	FALSE	0	ECT2	901466	Infinity	0.02657018
788709	taxon:9606	2.29557271	1055.986141	6.68E-04	177143	1902	tumor protein p73	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006298-&&-mismatch repair-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0010165-&&-response to X-ray-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0051262-&&-protein tetramerization-%%-GO:0016032-&&-viral process-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0042493-&&-response to drug-%%-GO:0034644-&&-cellular response to UV-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0001822-&&-kidney development-%%-GO:0043508-&&-negative regulation of JUN kinase activity|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0000785-&&-chromatin-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding	G:9606:TP73			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04390-&&-Hippo signaling pathway	TP73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP73	0.503610675	0.43562114	0.09032258	127	4	0.01548319	FALSE	16.125	TP73	TP73	136.312	18.03326453	0	126	0	0.78407121	FALSE	1	TP73	921664	Infinity	0.0312749
788861	taxon:9606	2.30927997	1577.434209	5.72E-04	176742	1902	voltage dependent anion channel 1	gene	biological_process-&-1&-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0007612-&&-learning-%%-GO:0006820-&&-anion transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0098656-&&-anion transmembrane transport-%%-GO:1903959-&&-regulation of anion transmembrane transport-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006851-&&-mitochondrial calcium ion transport-%%-GO:0007270-&&-neuron-neuron synaptic transmission-%%-GO:0001662-&&-behavioral fear response-%%-GO:0016032-&&-viral process-%%-GO:1903146-&&-regulation of mitophagy|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0016020-&&-membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005739-&&-mitochondrion-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0008308-&&-voltage-gated anion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0015288-&&-porin activity	G:9606:VDAC1			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa04217-&&-Necroptosis-%%-hsa05164-&&-Influenza A-%%-hsa04022-&&-cGMP-PKG signaling pathway	VDAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDAC1	0.500155909	0.43303541	0.1056118	127	4	0.013530251	FALSE	13.3373494	VDAC1	VDAC1	130.7007874	17.11129735	0	127	0	0.78178667	FALSE	0	VDAC1	900530	Infinity	0.03062158
789608	taxon:9606	2.29068851	1401.154945	2.52E-04	175061	1902	thyroid hormone receptor associated protein 3	gene	biological_process-&-1&-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0008380-&&-RNA splicing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016592-&&-mediator complex-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding	G:9606:THRAP3				THRAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRAP3	0.510828025	0.43654997	0.17035371	127	4	0.027934087	FALSE	23.34545455	THRAP3	THRAP3	201.8503937	27.97502569	0	127	0	0.78488525	FALSE	0	THRAP3	714650	Infinity	0.04591504
789801	taxon:9606	2.34599023	1038.024193	2.22E-04	174634	1902	serine and arginine repetitive matrix 1	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRRM1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	SRRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRRM1	0.506632975	0.42625923	0.16772903	127	4	0.023850977	FALSE	23.66019417	SRRM1	SRRM1	156.7795276	27.28626919	0	127	0	0.77566829	FALSE	0	SRRM1	465494	Infinity	0.03871099
790412	taxon:9606	2.32030881	408.0603103	9.62E-05	140313	1902	40S ribosomal protein S26	gene		G:9606:LOC101929876				LOC101929876	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC101929876	0.506313131	0.43097712	0.47556555	127	4	0.041999593	FALSE	63.22881356	LOC101929876	LOC101929876	208.8346457	67.82733414	0	127	0	0.77994853	FALSE	0	LOC101929876	363948	Infinity	0.0496516
790538	taxon:9606	2.27162439	1231.414169	4.33E-04	172545	1902	pre-mRNA processing factor 19	gene	biological_process-&-1&-GO:0034613-&&-cellular protein localization-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0000349-&&-generation of catalytic spliceosome for first transesterification step-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0072422-&&-signal transduction involved in DNA damage checkpoint|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0071006-&&-U2-type catalytic step 1 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0035861-&&-site of double-strand break-%%-GO:0000974-&&-Prp19 complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PRPF19			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03040-&&-Spliceosome	PRPF19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF19	0.511153601	0.44021362	0.20495673	126	4	0.028922891	FALSE	30.19090909	PRPF19	PRPF19	201.7741936	35.70649737	0	125	0	0.7880626	FALSE	1	PRPF19	715750	Infinity	0.0447258
787490	taxon:9606	2.42697337	1111.239548	4.10E-04	179347	1902	lysine methyltransferase 2A	gene	biological_process-&-1&-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0051899-&&-membrane depolarization-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0048172-&&-regulation of short-term neuronal synaptic plasticity-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0008542-&&-visual learning-%%-GO:0009791-&&-post-embryonic development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:1901674-&&-regulation of histone H3-K27 acetylation-%%-GO:2001040-&&-positive regulation of cellular response to drug-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0035864-&&-response to potassium ion-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0048536-&&-spleen development-%%-GO:0035640-&&-exploration behavior-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0044648-&&-histone H3-K4 dimethylation-%%-GO:0006306-&&-DNA methylation-%%-GO:0071440-&&-regulation of histone H3-K14 acetylation-%%-GO:0032411-&&-positive regulation of transporter activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0071339-&&-MLL1 complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0045322-&&-unmethylated CpG binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0003680-&&-AT DNA binding	G:9606:KMT2A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa00310-&&-Lysine degradation	KMT2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT2A	0.490220049	0.41203583	0.17781275	126	4	0.021398144	FALSE	26.08333333	KMT2A	KMT2A	163.5241936	30.04624182	0	125	0	0.7621711	FALSE	1	KMT2A	826242	Infinity	0.04592244
792235	taxon:9606	2.23381125	1080.813854	6.91E-04	182369	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	gene	biological_process-&-1&-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0006933-&&-negative regulation of cell adhesion involved in substrate-bound cell migration-%%-GO:0015992-&&-proton transport-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005754-&&-mitochondrial proton-transporting ATP synthase, catalytic core-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005215-&&-transporter activity-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0005524-&&-ATP binding	G:9606:ATP5B			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5B	0.508721852	0.4476654	0.12825397	126	4	0.025551977	FALSE	19.02150538	ATP5B	ATP5B	198.7698413	21.42813597	0	126	0	0.79436479	FALSE	0	ATP5B	1204234	Infinity	0.04189419
790147	taxon:9606	2.23286592	1030.687558	2.97E-04	173772	1902	chaperonin containing TCP1 subunit 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0009615-&&-response to virus-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0031681-&&-G-protein beta-subunit binding	G:9606:CCT5				CCT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT5	0.511316544	0.44785493	0.16266667	126	4	0.025588706	FALSE	22.08163265	CCT5	CCT5	206.3968254	25.03157912	0	126	0	0.79452235	FALSE	0	CCT5	834742	Infinity	0.04338635
787481	taxon:9606	2.37797385	773.775231	6.82E-04	179352	1902	mutL homolog 1	gene	biological_process-&-1&-GO:0007060-&&-male meiosis chromosome segregation-%%-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0051257-&&-meiotic spindle midzone assembly-%%-GO:0006298-&&-mismatch repair-%%-GO:0043060-&&-meiotic metaphase I plate congression-%%-GO:0045190-&&-isotype switching-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016321-&&-female meiosis chromosome segregation-%%-GO:0048477-&&-oogenesis-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007129-&&-synapsis-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0045950-&&-negative regulation of mitotic recombination-%%-GO:0045141-&&-meiotic telomere clustering|cellular_component-&-1&-GO:0005712-&&-chiasma-%%-GO:0005715-&&-late recombination nodule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032389-&&-MutLalpha complex-%%-GO:0005634-&&-nucleus-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0016020-&&-membrane-%%-GO:0000795-&&-synaptonemal complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0032407-&&-MutSalpha complex binding-%%-GO:0032137-&&-guanine/thymine mispair binding	G:9606:MLH1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05213-&&-Endometrial cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05226-&&-Gastric cancer	MLH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLH1	0.49644073	0.42052607	0.05341935	125	4	0.011464035	FALSE	8.630769231	MLH1	MLH1	100.864	9.382369869	0	125	0	0.77033769	FALSE	0	MLH1	830452	Infinity	0.02620697
787527	taxon:9606	2.28769497	1061.15258	5.64E-04	179256	1902	mutS homolog 2	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006298-&&-mismatch repair-%%-GO:0045190-&&-isotype switching-%%-GO:0006301-&&-postreplication repair-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0007281-&&-germ cell development-%%-GO:0010165-&&-response to X-ray-%%-GO:0010224-&&-response to UV-B-%%-GO:0016447-&&-somatic recombination of immunoglobulin gene segments-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0006281-&&-DNA repair-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0019724-&&-B cell mediated immunity-%%-GO:0008584-&&-male gonad development-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0006302-&&-double-strand break repair|cellular_component-&-1&-GO:0032302-&&-MutSbeta complex-%%-GO:0032301-&&-MutSalpha complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0032143-&&-single thymine insertion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0019237-&&-centromeric DNA binding-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0043531-&&-ADP binding-%%-GO:0032139-&&-dinucleotide insertion or deletion binding-%%-GO:0032137-&&-guanine/thymine mispair binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032181-&&-dinucleotide repeat insertion binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0032142-&&-single guanine insertion binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:MSH2	MSH2	TRUE	KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance	MSH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSH2	0.503136763	0.43712121	0.09902706	125	4	0.017654065	FALSE	16.26506024	MSH2	MSH2	152.2276423	18.55883429	0	124	0	0.78538417	FALSE	1	MSH2	891200	Infinity	0.0344879
788242	taxon:9606	2.39688042	1008.227696	9.01E-04	178016	1902	siah E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007399-&&-nervous system development-%%-GO:0031648-&&-protein destabilization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007411-&&-axon guidance-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:SIAH1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	SIAH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIAH1	0.492175514	0.41720897	0.04544849	125	4	0.01347019	FALSE	9.888888889	SIAH1	SIAH1	110.7886179	11.46578155	0	124	0	0.7671866	FALSE	1	SIAH1	1179292	Infinity	0.02976292
788296	taxon:9606	2.35213487	888.9892509	1.29E-04	177939	1902	ribosomal protein S27	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0008283-&&-cell proliferation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS27			KEGG-&-1&-hsa03010-&&-Ribosome	RPS27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS27	0.507434356	0.42514569	0.42049847	125	4	0.038153473	FALSE	55.41025641	RPS27	RPS27	193.3170732	59.28913464	0	124	0	0.77464419	FALSE	1	RPS27	326776	Infinity	0.04820266
792386	taxon:9606	2.38853001	726.1976565	5.30E-04	182111	1902	cAMP responsive element binding protein 1	gene	biological_process-&-1&-GO:0033762-&&-response to glucagon-%%-GO:0050821-&&-protein stabilization-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0007595-&&-lactation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0032916-&&-positive regulation of transforming growth factor beta3 production-%%-GO:0010033-&&-response to organic substance-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0071294-&&-cellular response to zinc ion-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0007623-&&-circadian rhythm-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0033363-&&-secretory granule organization-%%-GO:1902065-&&-response to L-glutamate-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008361-&&-regulation of cell size-%%-GO:0034670-&&-chemotaxis to arachidonic acid-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0046887-&&-positive regulation of hormone secretion-%%-GO:0060509-&&-Type I pneumocyte differentiation-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0007165-&&-signal transduction-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0021983-&&-pituitary gland development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007411-&&-axon guidance-%%-GO:0055025-&&-positive regulation of cardiac muscle tissue development-%%-GO:0007568-&&-aging-%%-GO:0007613-&&-memory-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0008542-&&-visual learning-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0048145-&&-regulation of fibroblast proliferation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060251-&&-regulation of glial cell proliferation-%%-GO:0014823-&&-response to activity-%%-GO:0035094-&&-response to nicotine-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0060430-&&-lung saccule development|cellular_component-&-1&-GO:1990589-&&-ATF4-CREB1 transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:1990763-&&-arrestin family protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding	G:9606:CREB1	CREB1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04916-&&-Melanogenesis-%%-hsa05152-&&-Tuberculosis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04911-&&-Insulin secretion-%%-hsa04710-&&-Circadian rhythm-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB1	0.481537076	0.41866755	0.11568706	125	4	0.014456131	FALSE	19.66197183	CREB1	CREB1	134.0569106	21.42898295	0	124	0	0.76857833	FALSE	1	CREB1	853148	Infinity	0.0353856
792438	taxon:9606	2.28942808	1242.962772	6.36E-04	182021	1902	C-terminal binding protein 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090241-&&-negative regulation of histone H4 acetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1903758-&&-negative regulation of transcription from RNA polymerase II promoter by histone modification-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0019079-&&-viral genome replication-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0031065-&&-positive regulation of histone deacetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0016616-&&-oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051287-&&-NAD binding	G:9606:CTBP1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	CTBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTBP1	0.499377335	0.43679031	0.08250033	125	4	0.012519872	FALSE	14.01298701	CTBP1	CTBP1	131.5121951	16.55829353	0	124	0	0.78509532	FALSE	1	CTBP1	936114	Infinity	0.029806
788381	taxon:9606	2.35575863	1132.755343	2.58E-04	177774	1902	structure specific recognition protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006260-&&-DNA replication-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:SSRP1				SSRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSRP1	0.501720363	0.42449171	0.19354839	125	4	0.027398653	FALSE	27.52	SSRP1	SSRP1	192.968	30.87976869	0	125	0	0.77404023	FALSE	0	SSRP1	632052	Infinity	0.04841355
792513	taxon:9606	2.2353868	1292.988061	2.01E-04	181875	1902	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	gene	biological_process-&-1&-GO:0006228-&&-UTP biosynthetic process-%%-GO:0044205-&&-'de novo' UMP biosynthetic process-%%-GO:0007507-&&-heart development-%%-GO:0014075-&&-response to amine-%%-GO:0031000-&&-response to caffeine-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0007595-&&-lactation-%%-GO:0032868-&&-response to insulin-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0046134-&&-pyrimidine nucleoside biosynthetic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0001889-&&-liver development-%%-GO:0007565-&&-female pregnancy-%%-GO:0019240-&&-citrulline biosynthetic process-%%-GO:0042594-&&-response to starvation-%%-GO:0051414-&&-response to cortisol-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0033574-&&-response to testosterone|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0042995-&&-cell projection-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004070-&&-aspartate carbamoyltransferase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004151-&&-dihydroorotase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004088-&&-carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070335-&&-aspartate binding-%%-GO:0019899-&&-enzyme binding	G:9606:CAD			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways	CAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAD	0.51360871	0.44734987	0.16753299	125	4	0.026576065	FALSE	23.73451327	CAD	CAD	208.0162602	27.51230832	0	124	0	0.7941022	FALSE	1	CAD	568922	Infinity	0.04381886
788473	taxon:9606	2.29510005	1269.558455	2.75E-04	177579	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SMARCC2			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCC2	0.508238276	0.43571085	0.16683871	125	4	0.023138322	FALSE	20.97029703	SMARCC2	SMARCC2	191.256	24.81660647	0	125	0	0.78414999	FALSE	0	SMARCC2	718694	Infinity	0.0436857
792740	taxon:9606	2.22924216	1227.031913	4.80E-04	181463	1902	dynein cytoplasmic 1 heavy chain 1	gene	biological_process-&-1&-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0034063-&&-stress granule assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0051293-&&-establishment of spindle localization-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008569-&&-ATP-dependent microtubule motor activity, minus-end-directed-%%-GO:0051959-&&-dynein light intermediate chain binding	G:9606:DYNC1H1			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome	DYNC1H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNC1H1	0.510015898	0.44858294	0.11419355	125	4	0.024341621	FALSE	16.04395604	DYNC1H1	DYNC1H1	204.856	17.51871577	0	125	0	0.79512631	FALSE	0	DYNC1H1	951154	Infinity	0.04287149
789345	taxon:9606	2.2687884	1422.482475	4.98E-04	175695	1902	structural maintenance of chromosomes 3	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0007165-&&-signal transduction-%%-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0008278-&&-cohesin complex-%%-GO:0005604-&&-basement membrane-%%-GO:0034991-&&-nuclear meiotic cohesin complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0030893-&&-meiotic cohesin complex-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0036033-&&-mediator complex binding-%%-GO:0003777-&&-microtubule motor activity	G:9606:SMC3			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis	SMC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC3	0.510015898	0.44076389	0.12890323	125	4	0.025827423	FALSE	17.96	SMC3	SMC3	212.36	20.66996452	0	125	0	0.78853527	FALSE	0	SMC3	1015710	Infinity	0.04679418
789372	taxon:9606	2.29762092	953.2775696	1.82E-04	175646	1902	DExD-box helicase 21	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0030515-&&-snoRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003723-&&-RNA binding	G:9606:DDX21				DDX21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX21	0.509853783	0.43523281	0.18735484	125	4	0.034366041	FALSE	25.09174312	DDX21	DDX21	232.168	27.6687228	0	125	0	0.78372985	FALSE	0	DDX21	590744	Infinity	0.05335969
790681	taxon:9606	2.19820388	1683.161448	7.61E-04	171481	1902	TANK binding kinase 1	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0009615-&&-response to virus-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032606-&&-type I interferon production-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0044565-&&-dendritic cell proliferation-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:1901214-&&-regulation of neuron death-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045359-&&-positive regulation of interferon-beta biosynthetic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006954-&&-inflammatory response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004672-&&-protein kinase activity	G:9606:TBK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	TBK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBK1	0.509853783	0.45491686	0.11895407	124	4	0.019667562	FALSE	18.26595745	TBK1	TBK1	176.7377049	21.91876368	0	123	0	0.80029935	FALSE	1	TBK1	1137044	Infinity	0.03555045
792179	taxon:9606	2.3332283	737.7662705	5.53E-04	182469	1902	ADP ribosylation factor 6	gene	biological_process-&-1&-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:0015031-&&-protein transport-%%-GO:0051301-&&-cell division-%%-GO:0031529-&&-ruffle organization-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:2000171-&&-negative regulation of dendrite development-%%-GO:0001889-&&-liver development-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0060998-&&-regulation of dendritic spine development-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0007155-&&-cell adhesion-%%-GO:0036010-&&-protein localization to endosome-%%-GO:0007049-&&-cell cycle-%%-GO:0033028-&&-myeloid cell apoptotic process-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0005768-&&-endosome-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0001726-&&-ruffle-%%-GO:0005938-&&-cell cortex-%%-GO:0043209-&&-myelin sheath-%%-GO:0055038-&&-recycling endosome membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0031996-&&-thioesterase binding	G:9606:ARF6	ARF6	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	ARF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF6	0.494298921	0.42859072	0.05441909	124	4	0.01360077	FALSE	8.328767123	ARF6	ARF6	113.0564516	9.343533931	0	124	0	0.77779528	FALSE	0	ARF6	743992	Infinity	0.02742718
788109	taxon:9606	2.28092012	1371.403428	0.00136466	178220	1902	protein tyrosine phosphatase, non-receptor type 1	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:1990264-&&-peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:1902202-&&-regulation of hepatocyte growth factor receptor signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033157-&&-regulation of intracellular protein transport-%%-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:2000646-&&-positive regulation of receptor catabolic process-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response|cellular_component-&-1&-GO:0098554-&&-cytoplasmic side of endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0097443-&&-sorting endosome-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0019899-&&-enzyme binding	G:9606:PTPN1	PTPN1	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04520-&&-Adherens junction	PTPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN1	0.49598021	0.43841956	0.05053516	124	4	0.009583456	FALSE	10.48484848	PTPN1	PTPN1	114.6803279	11.92562964	0	123	0	0.78651331	FALSE	1	PTPN1	1450742	Infinity	0.0258401
792374	taxon:9606	2.3614306	1944.188999	4.09E-04	165744	1902	SSX family member 2 interacting protein	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0051297-&&-centrosome organization-%%-GO:0007155-&&-cell adhesion-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0035735-&&-intraciliary transport involved in cilium assembly|cellular_component-&-1&-GO:0034451-&&-centriolar satellite-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding	G:9606:SSX2IP			KEGG-&-1&-hsa04520-&&-Adherens junction	SSX2IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSX2IP	0.495520544	0.42347211	0.08996071	124	4	0.009067056	FALSE	12.3164557	SSX2IP	SSX2IP	104.9180328	16.60618738	0	123	0	0.7730949	FALSE	1	SSX2IP	644922	Infinity	0.02647487
788596	taxon:9606	2.3349614	1071.184021	9.62E-04	177369	1902	transcription factor 4	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0065004-&&-protein-DNA complex assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001093-&&-TFIIB-class transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001011-&&-transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001087-&&-transcription factor activity, TFIIB-class binding	G:9606:TCF4				TCF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF4	0.492780338	0.4282726	0.04470939	124	4	0.009450727	FALSE	9.5	TCF4	TCF4	104.204918	10.17016593	0	123	0	0.77750643	FALSE	1	TCF4	1132636	Infinity	0.02536947
792706	taxon:9606	2.51378604	466.100544	7.19E-04	165150	1902	keratin 40	gene	biological_process-&-1&-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:KRT40			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT40	0.453235377	0.39780633	0.01403095	124	4	0.004605203	FALSE	2.75	KRT40	KRT40	58.2983871	2.830647131	0	124	0	0.74770233	FALSE	0	KRT40	858618	Infinity	0.01972455
788736	taxon:9606	2.26075311	861.7793567	7.99E-04	177064	1902	tumor susceptibility 101	gene	biological_process-&-1&-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1990182-&&-exosomal secretion-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0046755-&&-viral budding-%%-GO:0016236-&&-macroautophagy-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0015031-&&-protein transport-%%-GO:0051301-&&-cell division-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0019058-&&-viral life cycle-%%-GO:0048524-&&-positive regulation of viral process-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903551-&&-regulation of extracellular exosome assembly-%%-GO:1903772-&&-regulation of viral budding via host ESCRT complex-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0043405-&&-regulation of MAP kinase activity-%%-GO:1903774-&&-positive regulation of viral budding via host ESCRT complex-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:1902186-&&-regulation of viral release from host cell-%%-GO:0016197-&&-endosomal transport-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:2000397-&&-positive regulation of ubiquitin-dependent endocytosis|cellular_component-&-1&-GO:0005770-&&-late endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000813-&&-ESCRT I complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005771-&&-multivesicular body-%%-GO:0010008-&&-endosome membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046790-&&-virion binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:TSG101			KEGG-&-1&-hsa04144-&&-Endocytosis	TSG101	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSG101	0.504243948	0.44233048	0.0613738	124	4	0.012735471	FALSE	11.83823529	TSG101	TSG101	128.0901639	12.88242101	0	123	0	0.78987448	FALSE	1	TSG101	1000288	Infinity	0.02798531
792869	taxon:9606	2.40192217	1211.05577	0.00110739	181250	1902	estrogen receptor 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:1900116-&&-extracellular negative regulation of signal transduction-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005576-&&-extracellular region-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0038052-&&-RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030284-&&-estrogen receptor activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0034056-&&-estrogen response element binding-%%-GO:0048019-&&-receptor antagonist activity	G:9606:ESR2	ESR2	TRUE	KEGG-&-1&-hsa01522-&&-Endocrine resistance-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	ESR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESR2	0.487982963	0.41633322	0.07004471	124	4	0.010828895	FALSE	11.95522388	ESR2	ESR2	102.4918033	13.66145901	0	123	0	0.76634631	FALSE	1	ESR2	1458284	Infinity	0.02772858
789011	taxon:9606	2.46982827	608.1346694	1.25E-04	176384	1902	splicing factor 3a subunit 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005686-&&-U2 snRNP-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:SF3A2			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3A2	0.495673671	0.40488645	0.21419862	124	4	0.025863195	FALSE	30.54455446	SF3A2	SF3A2	156	34.30089691	0	123	0	0.75502862	FALSE	1	SF3A2	309046	Infinity	0.04731077
790136	taxon:9606	2.23664723	1216.5897	5.27E-04	173794	1902	microtubule associated protein RP/EB family member 1	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:1904527-&&-negative regulation of microtubule binding-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0008283-&&-cell proliferation-%%-GO:1903033-&&-positive regulation of microtubule plus-end binding|cellular_component-&-1&-GO:0031253-&&-cell projection membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0030981-&&-cortical microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0005819-&&-spindle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003723-&&-RNA binding	G:9606:MAPRE1				MAPRE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPRE1	0.506793049	0.44709777	0.10242515	124	4	0.016315619	FALSE	15.41463415	MAPRE1	MAPRE1	158.704918	17.44930619	0	123	0	0.79389213	FALSE	1	MAPRE1	891806	Infinity	0.0335582
787895	taxon:9606	2.34961399	1605.281465	2.71E-04	178644	1902	proteasome 26S subunit, non-ATPase 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PSMD3	PSMD3	TRUE	KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD3	0.503294634	0.42560182	0.21378115	123	4	0.018849514	FALSE	27.88	PSMD3	PSMD3	154.9593496	34.9698062	0	123	0	0.77506433	FALSE	0	PSMD3	602498	Infinity	0.03849114
788183	taxon:9606	2.3318103	1023.59176	4.59E-04	178113	1902	retinoic acid receptor alpha	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001889-&&-liver development-%%-GO:0007565-&&-female pregnancy-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0045947-&&-negative regulation of translational initiation-%%-GO:0060173-&&-limb development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003417-&&-growth plate cartilage development-%%-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0051099-&&-positive regulation of binding-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0061037-&&-negative regulation of cartilage development-%%-GO:0030850-&&-prostate gland development-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0033189-&&-response to vitamin A-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0060010-&&-Sertoli cell fate commitment-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0007165-&&-signal transduction-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0060591-&&-chondroblast differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001657-&&-ureteric bud development-%%-GO:0032355-&&-response to estradiol-%%-GO:0001843-&&-neural tube closure-%%-GO:0032736-&&-positive regulation of interleukin-13 production-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0032754-&&-positive regulation of interleukin-5 production-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0060534-&&-trachea cartilage development-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0034097-&&-response to cytokine-%%-GO:0021766-&&-hippocampus development-%%-GO:0030853-&&-negative regulation of granulocyte differentiation-%%-GO:0007281-&&-germ cell development-%%-GO:0031641-&&-regulation of myelination-%%-GO:0045471-&&-response to ethanol-%%-GO:0002068-&&-glandular epithelial cell development-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0060324-&&-face development-%%-GO:0071391-&&-cellular response to estrogen stimulus|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005102-&&-receptor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000900-&&-translation repressor activity, nucleic acid binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0044323-&&-retinoic acid-responsive element binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0001972-&&-retinoic acid binding-%%-GO:0008144-&&-drug binding-%%-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:RARA			KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	RARA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RARA	0.499066584	0.42885135	0.10881543	123	4	0.014345024	FALSE	16.24390244	RARA	RARA	131.6198347	19.06827706	0	122	0	0.77803162	FALSE	1	RARA	753840	Infinity	0.03177089
788491	taxon:9606	2.35670395	764.509794	2.35E-04	177553	1902	small nuclear ribonucleoprotein polypeptide A'	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005686-&&-U2 snRNP-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030620-&&-U2 snRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNRPA1			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPA1	0.503452605	0.42432143	0.19938691	123	4	0.027453067	FALSE	28.4	SNRPA1	SNRPA1	187.8699187	31.18779149	0	123	0	0.77388267	FALSE	0	SNRPA1	575192	Infinity	0.04714998
788493	taxon:9606	2.23365369	905.8551362	2.98E-04	177555	1902	small nuclear ribonucleoprotein U1 subunit 70	gene	biological_process-&-1&-GO:0043462-&&-regulation of ATPase activity-%%-GO:0061084-&&-negative regulation of protein refolding-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008380-&&-RNA splicing-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:1904715-&&-negative regulation of chaperone-mediated autophagy|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005685-&&-U1 snRNP-%%-GO:0000243-&&-commitment complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030619-&&-U1 snRNA binding	G:9606:SNRNP70			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRNP70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRNP70	0.510340439	0.44769697	0.21111555	123	4	0.032315481	FALSE	28.81904762	SNRNP70	SNRNP70	240.2845529	31.71551139	0	123	0	0.79439105	FALSE	0	SNRNP70	786328	Infinity	0.05058622
788870	taxon:9606	2.26343154	1099.335353	6.96E-04	176730	1902	ezrin	gene	biological_process-&-1&-GO:0072697-&&-protein localization to cell cortex-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0046847-&&-filopodium assembly-%%-GO:0030033-&&-microvillus assembly-%%-GO:1903753-&&-negative regulation of p38MAPK cascade-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0031623-&&-receptor internalization-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0043622-&&-cortical microtubule organization-%%-GO:0001951-&&-intestinal D-glucose absorption-%%-GO:1902115-&&-regulation of organelle assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0008361-&&-regulation of cell size-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0007411-&&-axon guidance-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0051660-&&-establishment of centrosome localization-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0032532-&&-regulation of microvillus length-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0003376-&&-sphingosine-1-phosphate signaling pathway-%%-GO:0022612-&&-gland morphogenesis-%%-GO:1902896-&&-terminal web assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:1902966-&&-positive regulation of protein localization to early endosome-%%-GO:0010737-&&-protein kinase A signaling-%%-GO:1900041-&&-negative regulation of interleukin-2 secretion-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0031532-&&-actin cytoskeleton reorganization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0001931-&&-uropod-%%-GO:0044297-&&-cell body-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0001726-&&-ruffle-%%-GO:0030175-&&-filopodium-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0036064-&&-ciliary basal body-%%-GO:0043209-&&-myelin sheath-%%-GO:0001650-&&-fibrillar center-%%-GO:0001772-&&-immunological synapse-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0031528-&&-microvillus membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005903-&&-brush border-%%-GO:0097454-&&-Schwann cell microvillus-%%-GO:0016020-&&-membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005902-&&-microvillus-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0051286-&&-cell tip-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0097449-&&-astrocyte projection-%%-GO:0030315-&&-T-tubule-%%-GO:0031982-&&-vesicle-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0044393-&&-microspike-%%-GO:0036398-&&-TCR signalosome-%%-GO:0098592-&&-cytoplasmic side of apical plasma membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0051117-&&-ATPase binding	G:9606:EZR			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	EZR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EZR	0.503610675	0.44180704	0.1	123	4	0.015380945	FALSE	15.3	EZR	EZR	154.338843	18.32858912	0	122	0	0.78942808	FALSE	1	EZR	1027352	Infinity	0.03385366
789025	taxon:9606	2.24972428	1662.771259	4.18E-04	176348	1902	ubiquitin specific peptidase 9, X-linked	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0048675-&&-axon extension-%%-GO:0007292-&&-female gamete generation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0001764-&&-neuron migration-%%-GO:0051301-&&-cell division-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070410-&&-co-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP9X				USP9X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP9X	0.506953224	0.44449891	0.09436226	123	4	0.017760213	FALSE	13.11702128	USP9X	USP9X	171.8536585	16.10646708	0	123	0	0.79171262	FALSE	0	USP9X	910356	Infinity	0.03695428
790657	taxon:9606	2.27225461	709.1427544	8.28E-04	138803	1902	LOC400927-CSNK1E readthrough	gene	biological_process-&-1&-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2000052-&&-positive regulation of non-canonical Wnt signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034613-&&-cellular protein localization-%%-GO:0007165-&&-signal transduction-%%-GO:0006364-&&-rRNA processing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905426-&&-positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048512-&&-circadian behavior-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding	G:9606:LOC400927-CSNK1E			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04710-&&-Circadian rhythm	LOC400927-CSNK1E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC400927-CSNK1E	0.499688474	0.44009153	0.07885154	122	4	0.01024967	FALSE	12.03174603	LOC400927-CSNK1E	LOC400927-CSNK1E	117.0666667	13.07971015	0	121	0	0.78795757	FALSE	1	LOC400927-CSNK1E	1162010	Infinity	0.02590544
790775	taxon:9606	2.53978257	186.3725957	8.86E-04	171249	1902	transmembrane protein 216	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005929-&&-cilium-%%-GO:0036038-&&-MKS complex	G:9606:TMEM216				TMEM216	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM216	0.418471171	0.39373449	0.01801924	122	4	0.002731812	FALSE	3.5	TMEM216	TMEM216	48.25409836	3.62962963	0	122	0	0.74336957	FALSE	0	TMEM216	880742	Infinity	0.01723406
787422	taxon:9606	2.32472034	817.6466034	6.07E-04	179462	1902	LCK proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030097-&&-hemopoiesis-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051249-&&-regulation of lymphocyte activation-%%-GO:0006882-&&-cellular zinc ion homeostasis-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050862-&&-positive regulation of T cell receptor signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0030217-&&-T cell differentiation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0016477-&&-cell migration-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0042493-&&-response to drug-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0000242-&&-pericentriolar material-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0001772-&&-immunological synapse|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0042609-&&-CD4 receptor binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042610-&&-CD8 receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:LCK			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	LCK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCK	0.490519878	0.43015927	0.10938375	122	4	0.009266371	FALSE	15.1971831	LCK	LCK	113.9916667	18.48768726	0	121	0	0.77921328	FALSE	1	LCK	874480	Infinity	0.02730594
791576	taxon:9606	2.50386009	568.5228337	3.81E-04	167945	1902	myosin XIX	gene	cellular_component-&-1&-GO:0016459-&&-myosin complex-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0060002-&&-plus-end directed microfilament motor activity-%%-GO:0032027-&&-myosin light chain binding-%%-GO:0016887-&&-ATPase activity	G:9606:MYO19				MYO19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO19	0.453876627	0.39938334	0.11990245	122	4	0.008795465	FALSE	15.62857143	MYO19	MYO19	81.92622951	18.28136677	0	122	0	0.74935665	FALSE	0	MYO19	535434	Infinity	0.02685374
787539	taxon:9606	2.3516622	871.563696	6.58E-04	179220	1902	protein phosphatase 2 catalytic subunit beta	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0046677-&&-response to antibiotic|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000159-&&-protein phosphatase type 2A complex|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2CB			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04140-&&-Autophagy - animal-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04136-&&-Autophagy - other-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway	PPP2CB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2CB	0.491572173	0.42523114	0.07830917	122	4	0.010507668	FALSE	9.876923077	PPP2CB	PPP2CB	109.8278689	11.00033693	0	122	0	0.77472297	FALSE	0	PPP2CB	883136	Infinity	0.02734214
791966	taxon:9606	2.36946589	720.4625136	0.00105136	182795	1902	annexin A7	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0035176-&&-social behavior-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0009651-&&-response to salt stress-%%-GO:0009992-&&-cellular water homeostasis-%%-GO:0051592-&&-response to calcium ion-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006914-&&-autophagy-%%-GO:0007599-&&-hemostasis-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042584-&&-chromaffin granule membrane|molecular_function-&-1&-GO:0005178-&&-integrin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0048306-&&-calcium-dependent protein binding	G:9606:ANXA7				ANXA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA7	0.48783455	0.42203604	0.02506435	122	4	0.010006941	FALSE	5.172413793	ANXA7	ANXA7	91.56557377	5.474067282	0	122	0	0.77175569	FALSE	0	ANXA7	1240908	Infinity	0.02363484
792418	taxon:9606	2.27225461	709.1427544	8.28E-04	182052	1902	casein kinase 1 epsilon	gene	biological_process-&-1&-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2000052-&&-positive regulation of non-canonical Wnt signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034613-&&-cellular protein localization-%%-GO:0007165-&&-signal transduction-%%-GO:0006364-&&-rRNA processing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905426-&&-positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048512-&&-circadian behavior-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding	G:9606:CSNK1E			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04710-&&-Circadian rhythm	CSNK1E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1E	0.499688474	0.44009153	0.07885154	122	4	0.01024967	FALSE	12.03174603	CSNK1E	CSNK1E	117.0666667	13.07971015	0	121	0	0.78795757	FALSE	1	CSNK1E	1162010	Infinity	0.02590544
792824	taxon:9606	2.2869072	1079.449384	5.96E-04	181300	1902	erythrocyte membrane protein band 4.1	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0014731-&&-spectrin-associated cytoskeleton-%%-GO:0030054-&&-cell junction-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043234-&&-protein complex-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030507-&&-spectrin binding	G:9606:EPB41				EPB41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41	0.502506266	0.43727179	0.06164476	122	4	0.013701681	FALSE	9.58974359	EPB41	EPB41	127.6885246	10.86382775	0	122	0	0.78551547	FALSE	0	EPB41	840994	Infinity	0.02891879
793288	taxon:9606	2.44194107	1015.766192	4.28E-04	180374	1902	histone cluster 1 H1 family member a	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:HIST1H1A				HIST1H1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1A	0.48783455	0.40951029	0.11529603	122	4	0.020745138	FALSE	17.68235294	HIST1H1A	HIST1H1A	141.9590164	19.73301386	0	122	0	0.75967649	FALSE	0	HIST1H1A	714810	Infinity	0.04114284
789452	taxon:9606	2.26201355	1057.919273	6.19E-04	175436	1902	BCL2 associated athanogene 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0019538-&&-protein metabolic process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:BAG2			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	BAG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG2	0.505834122	0.442084	0.09747899	122	4	0.019292975	FALSE	15.49411765	BAG2	BAG2	174.125	17.35984962	0	121	0	0.78966441	FALSE	1	BAG2	1079080	Infinity	0.03809446
791824	taxon:9606	2.36773279	677.2817954	0.0010455	166686	1902	ligand of numb-protein X 1	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:LNX1				LNX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LNX1	0.470933647	0.42234496	0.02036747	121	4	0.006077731	FALSE	5.738095238	LNX1	LNX1	80.35294118	6.074747018	0	120	0	0.77204454	FALSE	1	LNX1	1014662	Infinity	0.02060088
788071	taxon:9606	2.31321884	501.2426023	9.12E-05	178286	1902	ribosomal protein L30	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0097421-&&-liver regeneration-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:1904571-&&-positive regulation of selenocysteine incorporation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0035368-&&-selenocysteine insertion sequence binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL30			KEGG-&-1&-hsa03010-&&-Ribosome	RPL30	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL30	0.504243948	0.43229805	0.51721763	121	4	0.041209407	FALSE	64.82758621	RPL30	RPL30	214.5123967	67.89716079	0	121	0	0.78113019	FALSE	0	RPL30	318376	Infinity	0.05037867
792611	taxon:9606	2.32030881	795.2186489	6.69E-04	181721	1902	E2F transcription factor 1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071930-&&-negative regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070345-&&-negative regulation of fat cell proliferation-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0030900-&&-forebrain development-%%-GO:1990086-&&-lens fiber cell apoptotic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0043276-&&-anoikis-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0071466-&&-cellular response to xenobiotic stimulus-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0035189-&&-Rb-E2F complex-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019901-&&-protein kinase binding	G:9606:E2F1	E2F1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05219-&&-Bladder cancer-%%-hsa05214-&&-Glioma-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	E2F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E2F1	0.498911353	0.43097712	0.1084022	121	4	0.01440075	FALSE	16.25	E2F1	E2F1	137.0165289	18.13640022	0	121	0	0.77994853	FALSE	0	E2F1	892912	Infinity	0.03255311
788728	taxon:9606	2.40523082	1768.39367	7.08E-04	177103	1902	thyroid hormone receptor interactor 6	gene	biological_process-&-1&-GO:0048041-&&-focal adhesion assembly-%%-GO:0008588-&&-release of cytoplasmic sequestered NF-kappaB-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0045323-&&-interleukin-1 receptor complex|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005149-&&-interleukin-1 receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TRIP6			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	TRIP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIP6	0.484299517	0.41576051	0.03076485	121	4	0.007790213	FALSE	6.594202899	TRIP6	TRIP6	82.87394958	7.925687146	0	120	0	0.76579486	FALSE	1	TRIP6	813612	Infinity	0.02262108
789333	taxon:9606	2.28911297	1282.104908	2.18E-04	175714	1902	poly(A) binding protein cytoplasmic 4	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0006412-&&-translation-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0017130-&&-poly(C) RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PABPC4			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa03018-&&-RNA degradation	PABPC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPC4	0.508399366	0.43685044	0.17699725	121	4	0.031293295	FALSE	23.52884615	PABPC4	PABPC4	221.6694215	26.18865621	0	121	0	0.78514784	FALSE	0	PABPC4	578472	Infinity	0.05022726
787601	taxon:9606	2.37655585	923.3099584	2.17E-04	179113	1902	nuclear factor kappa B subunit 2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0002467-&&-germinal center formation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0045087-&&-innate immune response-%%-GO:0034097-&&-response to cytokine-%%-GO:0002268-&&-follicular dendritic cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006954-&&-inflammatory response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0048511-&&-rhythmic process-%%-GO:0007568-&&-aging-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048536-&&-spleen development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033257-&&-Bcl3/NF-kappaB2 complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NFKB2			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05134-&&-Legionellosis	NFKB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKB2	0.50125	0.42077698	0.15167319	120	4	0.025124775	FALSE	21.1980198	NFKB2	NFKB2	152.9067797	23.24982728	0	119	0	0.77057402	FALSE	1	NFKB2	437556	Infinity	0.03965794
791962	taxon:9606	2.18654482	1301.686329	4.91E-04	182803	1902	annexin A2	gene	biological_process-&-1&-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0007589-&&-body fluid secretion-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0032804-&&-negative regulation of low-density lipoprotein particle receptor catabolic process-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0001525-&&-angiogenesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030199-&&-collagen fibril organization-%%-GO:1905581-&&-positive regulation of low-density lipoprotein particle clearance-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0036035-&&-osteoclast development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0097066-&&-response to thyroid hormone-%%-GO:1905599-&&-positive regulation of low-density lipoprotein receptor activity-%%-GO:1905602-&&-positive regulation of receptor-mediated endocytosis involved in cholesterol transport-%%-GO:0001765-&&-membrane raft assembly-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0042730-&&-fibrinolysis-%%-GO:1905597-&&-positive regulation of low-density lipoprotein particle receptor binding-%%-GO:0006900-&&-membrane budding|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0031902-&&-late endosome membrane-%%-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0044354-&&-macropinosome-%%-GO:0042470-&&-melanosome-%%-GO:0005604-&&-basement membrane-%%-GO:0030496-&&-midbody-%%-GO:0031012-&&-extracellular matrix-%%-GO:1990667-&&-PCSK9-AnxA2 complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005768-&&-endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0035749-&&-myelin sheath adaxonal region-%%-GO:0001726-&&-ruffle-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0019897-&&-extrinsic component of plasma membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0019834-&&-phospholipase A2 inhibitor activity-%%-GO:0030546-&&-receptor activator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion	G:9606:ANXA2				ANXA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA2	0.511479592	0.45734256	0.12745098	120	4	0.025625918	FALSE	17.60824742	ANXA2	ANXA2	226.8416667	19.77294147	0	120	0	0.80224253	FALSE	0	ANXA2	1082862	Infinity	0.04497654
787902	taxon:9606	2.24499764	2170.095919	3.50E-04	178637	1902	proteasome 26S subunit, non-ATPase 11	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043248-&&-proteasome assembly-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:PSMD11			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD11	0.511153601	0.44543477	0.20672269	120	4	0.019527065	FALSE	26.6372549	PSMD11	PSMD11	174.6333333	33.17976538	0	120	0	0.79250039	FALSE	0	PSMD11	792978	Infinity	0.03733782
792276	taxon:9606	2.33054987	674.5103051	6.89E-04	182305	1902	cadherin 1	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0021983-&&-pituitary gland development-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0034332-&&-adherens junction organization-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0031175-&&-neuron projection development-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0042493-&&-response to drug-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0007416-&&-synapse assembly-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0022408-&&-negative regulation of cell-cell adhesion|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043296-&&-apical junction complex-%%-GO:0005768-&&-endosome-%%-GO:0016600-&&-flotillin complex-%%-GO:0005576-&&-extracellular region-%%-GO:0030027-&&-lamellipodium-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016342-&&-catenin complex-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0030506-&&-ankyrin binding	G:9606:CDH1	CDH1	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05213-&&-Endometrial cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05216-&&-Thyroid cancer-%%-hsa05226-&&-Gastric cancer	CDH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDH1	0.496748219	0.42908329	0.05838041	120	4	0.010901529	FALSE	11.07462687	CDH1	CDH1	111.9830509	12.08631127	0	119	0	0.77824169	FALSE	1	CDH1	861044	Infinity	0.02704778
788469	taxon:9606	2.25665669	978.0939876	2.86E-04	177580	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0030850-&&-prostate gland development-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0001741-&&-XY body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SMARCC1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCC1	0.510990761	0.44313342	0.18108069	120	4	0.022420818	FALSE	23.55789474	SMARCC1	SMARCC1	200.1694915	26.84918112	0	119	0	0.79055722	FALSE	1	SMARCC1	729156	Infinity	0.04335488
788557	taxon:9606	2.44651016	855.9180249	5.46E-04	177446	1902	suppressor of variegation 3-9 homolog 1	gene	biological_process-&-1&-GO:0036124-&&-histone H3-K9 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0006364-&&-rRNA processing-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0036123-&&-histone H3-K9 dimethylation-%%-GO:0048511-&&-rhythmic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071456-&&-cellular response to hypoxia|cellular_component-&-1&-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000792-&&-heterochromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0033553-&&-rDNA heterochromatin-%%-GO:0005652-&&-nuclear lamina-%%-GO:0000794-&&-condensed nuclear chromosome|molecular_function-&-1&-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0046974-&&-histone methyltransferase activity (H3-K9 specific)-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity	G:9606:SUV39H1			KEGG-&-1&-hsa00310-&&-Lysine degradation	SUV39H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUV39H1	0.478092399	0.40874549	0.12385919	120	4	0.014778054	FALSE	20.79166667	SUV39H1	SUV39H1	129.8135593	22.52282899	0	119	0	0.75891497	FALSE	1	SUV39H1	827068	Infinity	0.03782067
789240	taxon:9606	2.32393257	727.5394718	8.08E-04	175920	1902	tumor protein p63	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0060529-&&-squamous basal epithelial stem cell differentiation involved in prostate gland acinus development-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0030859-&&-polarized epithelial cell differentiation-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0051289-&&-protein homotetramerization-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0048807-&&-female genitalia morphogenesis-%%-GO:0060513-&&-prostatic bud formation-%%-GO:0007283-&&-spermatogenesis-%%-GO:2000381-&&-negative regulation of mesoderm development-%%-GO:0010482-&&-regulation of epidermal cell division-%%-GO:0048745-&&-smooth muscle tissue development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045617-&&-negative regulation of keratinocyte differentiation-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0060157-&&-urinary bladder development-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0007499-&&-ectoderm and mesoderm interaction-%%-GO:0001501-&&-skeletal system development-%%-GO:0010165-&&-response to X-ray-%%-GO:0010838-&&-positive regulation of keratinocyte proliferation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001736-&&-establishment of planar polarity-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:2000271-&&-positive regulation of fibroblast apoptotic process-%%-GO:0010481-&&-epidermal cell division-%%-GO:0001302-&&-replicative cell aging-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0002064-&&-epithelial cell development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0060197-&&-cloacal septation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:TP63	TP63	TRUE	KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	TP63	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP63	0.497672975	0.43030508	0.07243228	120	4	0.015923528	FALSE	13.76712329	TP63	TP63	128.0254237	14.78160667	0	119	0	0.77934457	FALSE	1	TP63	932884	Infinity	0.03060658
789416	taxon:9606	2.28643454	928.3993228	2.20E-04	175530	1902	elongation factor Tu GTP binding domain containing 2	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0035690-&&-cellular response to drug-%%-GO:0006397-&&-mRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0042220-&&-response to cocaine|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:EFTUD2			KEGG-&-1&-hsa03040-&&-Spliceosome	EFTUD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EFTUD2	0.50952986	0.43736218	0.21338548	120	4	0.028961353	FALSE	29.1372549	EFTUD2	EFTUD2	213.5762712	32.26137925	0	119	0	0.78559424	FALSE	1	EFTUD2	532628	Infinity	0.04820943
789480	taxon:9606	2.37450764	932.6290745	3.23E-04	175374	1902	nuclear receptor corepressor 2	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0072365-&&-regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005112-&&-Notch binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:NCOR2			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection	NCOR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOR2	0.489173529	0.42113994	0.14985994	120	4	0.01629021	FALSE	19.88636364	NCOR2	NCOR2	148.6083333	24.02722739	0	120	0	0.77091539	FALSE	0	NCOR2	659768	Infinity	0.03833849
789784	taxon:9606	2.34173625	1527.335583	5.23E-04	174686	1902	proteasome activator subunit 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0008537-&&-proteasome activator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0097371-&&-MDM2/MDM4 family protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0061133-&&-endopeptidase activator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0002039-&&-p53 binding	G:9606:PSME3			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa05160-&&-Hepatitis C	PSME3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSME3	0.50140669	0.42703357	0.09459655	120	4	0.01486554	FALSE	16.3452381	PSME3	PSME3	133.3050848	18.21363633	0	119	0	0.77637729	FALSE	1	PSME3	774490	Infinity	0.03272215
787594	taxon:9606	2.37198677	1049.429252	5.23E-04	179126	1902	nuclear factor of activated T-cells 1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0005528-&&-FK506 binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001225-&&-RNA polymerase II transcription coactivator binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding	G:9606:NFATC1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	NFATC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFATC1	0.493538462	0.42158751	0.09129754	119	4	0.013806009	FALSE	11.91025641	NFATC1	NFATC1	129.4369748	13.66281656	0	119	0	0.77133554	FALSE	0	NFATC1	773446	Infinity	0.0331867
787888	taxon:9606	2.27477548	1250.644946	4.20E-04	178653	1902	proteasome 26S subunit, ATPase 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006457-&&-protein folding-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005634-&&-nucleus-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC1			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	PSMC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC1	0.509368053	0.43960382	0.22318758	119	4	0.017918574	FALSE	29.48958333	PSMC1	PSMC1	161.2436975	35.80801821	0	119	0	0.78753742	FALSE	0	PSMC1	725082	Infinity	0.03587467
792486	taxon:9606	2.31778793	654.6286664	0.00188325	181946	1902	BCL2, apoptosis regulator	gene	biological_process-&-1&-GO:0030318-&&-melanocyte differentiation-%%-GO:0033033-&&-negative regulation of myeloid cell apoptotic process-%%-GO:0048753-&&-pigment granule organization-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0042493-&&-response to drug-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0009636-&&-response to toxic substance-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0051607-&&-defense response to virus-%%-GO:0010523-&&-negative regulation of calcium ion transport into cytosol-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007015-&&-actin filament organization-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0002931-&&-response to ischemia-%%-GO:0006808-&&-regulation of nitrogen utilization-%%-GO:0048538-&&-thymus development-%%-GO:0006915-&&-apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0014031-&&-mesenchymal cell development-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0009314-&&-response to radiation-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0021747-&&-cochlear nucleus development-%%-GO:0006959-&&-humoral immune response-%%-GO:0043029-&&-T cell homeostasis-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0007569-&&-cell aging-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0001662-&&-behavioral fear response-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0002326-&&-B cell lineage commitment-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0032835-&&-glomerulus development-%%-GO:0045069-&&-regulation of viral genome replication-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0002320-&&-lymphoid progenitor cell differentiation-%%-GO:0010039-&&-response to iron ion-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:0003014-&&-renal system process-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0001656-&&-metanephros development-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0032848-&&-negative regulation of cellular pH reduction-%%-GO:0051902-&&-negative regulation of mitochondrial depolarization-%%-GO:0016049-&&-cell growth-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0045636-&&-positive regulation of melanocyte differentiation-%%-GO:0046671-&&-negative regulation of retinal cell programmed cell death-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007409-&&-axonogenesis-%%-GO:0043583-&&-ear development-%%-GO:0048536-&&-spleen development-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0022898-&&-regulation of transmembrane transporter activity-%%-GO:0034097-&&-response to cytokine-%%-GO:0035094-&&-response to nicotine-%%-GO:0048599-&&-oocyte development-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0007565-&&-female pregnancy-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0001503-&&-ossification-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0008584-&&-male gonad development-%%-GO:0009791-&&-post-embryonic development-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0031647-&&-regulation of protein stability-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0006582-&&-melanin metabolic process-%%-GO:0010224-&&-response to UV-B-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0010559-&&-regulation of glycoprotein biosynthetic process-%%-GO:0035265-&&-organ growth-%%-GO:0043375-&&-CD8-positive, alpha-beta T cell lineage commitment-%%-GO:0031103-&&-axon regeneration-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0048743-&&-positive regulation of skeletal muscle fiber development|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0016248-&&-channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0015267-&&-channel activity-%%-GO:0002020-&&-protease binding-%%-GO:0051434-&&-BH3 domain binding-%%-GO:0008134-&&-transcription factor binding	G:9606:BCL2	BCL2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa05226-&&-Gastric cancer	BCL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2	0.495520544	0.43144586	0.06822871	119	4	0.010352057	FALSE	12.09677419	BCL2	BCL2	113.974359	13.37121678	0	118	0	0.78036868	FALSE	1	BCL2	2100170	Infinity	0.0269765
788575	taxon:9606	2.29226406	889.6516109	7.02E-04	177408	1902	mitogen-activated protein kinase kinase kinase 7	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0043276-&&-anoikis-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:MAP3K7			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	MAP3K7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K7	0.498601181	0.43624991	0.09416446	119	4	0.011648179	FALSE	15.09589041	MAP3K7	MAP3K7	125.4358974	17.20494313	0	118	0	0.78462266	FALSE	1	MAP3K7	902722	Infinity	0.02860245
792696	taxon:9606	2.23018749	609.8411637	2.70E-04	181551	1902	DEAD-box helicase 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0006302-&&-double-strand break repair-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0007275-&&-multicellular organism development-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0071920-&&-cleavage body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0072669-&&-tRNA-splicing ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0033677-&&-DNA/RNA helicase activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0004518-&&-nuclease activity-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0004527-&&-exonuclease activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DDX1				DDX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX1	0.50969177	0.44839279	0.19256516	119	4	0.029752167	FALSE	25.6	DDX1	DDX1	229.7226891	28.18691447	0	119	0	0.79496875	FALSE	0	DDX1	609870	Infinity	0.04805914
789019	taxon:9606	2.28659209	832.7263632	3.91E-04	176370	1902	nuclear receptor coactivator 3	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035624-&&-receptor transactivation-%%-GO:2001141-&&-regulation of RNA biosynthetic process-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0016573-&&-histone acetylation-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:NCOA3	NCOA3	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	NCOA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA3	0.503452605	0.43733205	0.14706749	119	4	0.018670291	FALSE	20.64444444	NCOA3	NCOA3	169.7094017	23.53474228	0	118	0	0.78556798	FALSE	1	NCOA3	758312	Infinity	0.0382573
787029	taxon:9606	2.28107767	656.37524	2.60E-04	180210	1902	heterogeneous nuclear ribonucleoprotein L	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0006396-&&-RNA processing-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0007623-&&-circadian rhythm-%%-GO:1901652-&&-response to peptide-%%-GO:0010467-&&-gene expression-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0045120-&&-pronucleus-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0097157-&&-pre-mRNA intronic binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:1990715-&&-mRNA CDS binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:HNRNPL				HNRNPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPL	0.508077289	0.43838928	0.2017991	118	4	0.032622404	FALSE	29.11458333	HNRNPL	HNRNPL	242.9568966	30.83295985	0	117	0	0.78648705	FALSE	1	HNRNPL	635918	Infinity	0.05442003
787835	taxon:9606	2.37561052	841.7149649	9.39E-04	178739	1902	mitogen-activated protein kinase 6	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0007165-&&-signal transduction-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0007049-&&-cell cycle-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0032156-&&-septin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAPK6			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	MAPK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK6	0.48783455	0.42094442	0.02623688	118	4	0.009696666	FALSE	6.746031746	MAPK6	MAPK6	90.75	7.198023089	0	117	0	0.77073158	FALSE	1	MAPK6	1039610	Infinity	0.02357893
787872	taxon:9606	2.29888136	913.1680708	2.19E-04	178670	1902	proteasome subunit alpha 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0009615-&&-response to virus-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0000932-&&-P-body-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA2			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA2	0.507273877	0.43499417	0.26686657	118	4	0.018577516	FALSE	34.11111111	PSMA2	PSMA2	168.4827586	41.91853479	0	117	0	0.78351977	FALSE	1	PSMA2	512230	Infinity	0.03874948
787909	taxon:9606	2.2405861	674.6356007	1.66E-04	178630	1902	polypyrimidine tract binding protein 1	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0006397-&&-mRNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0051148-&&-negative regulation of muscle cell differentiation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0008187-&&-poly-pyrimidine tract binding-%%-GO:0003723-&&-RNA binding-%%-GO:0036002-&&-pre-mRNA binding	G:9606:PTBP1				PTBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTBP1	0.510502864	0.44631179	0.23373313	118	4	0.031557683	FALSE	31	PTBP1	PTBP1	236.7413793	34.26820032	0	117	0	0.79323565	FALSE	1	PTBP1	453596	Infinity	0.05021026
792144	taxon:9606	2.27288483	1349.277023	5.56E-04	182521	1902	actinin alpha 1	gene	biological_process-&-1&-GO:0070527-&&-platelet aggregation-%%-GO:0030168-&&-platelet activation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0007015-&&-actin filament organization-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0051639-&&-actin filament network formation-%%-GO:0051271-&&-negative regulation of cellular component movement-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0036344-&&-platelet morphogenesis-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030220-&&-platelet formation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0005884-&&-actin filament-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0031143-&&-pseudopodium-%%-GO:0001726-&&-ruffle-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0051015-&&-actin filament binding	G:9606:ACTN1			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction	ACTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTN1	0.504878816	0.4399695	0.0838081	118	4	0.014996372	FALSE	13.24691358	ACTN1	ACTN1	148.8448276	15.95465459	0	117	0	0.78785253	FALSE	1	ACTN1	873624	Infinity	0.03303226
788085	taxon:9606	2.40995746	867.2753929	1.79E-04	178267	1902	ribosomal protein lateral stalk subunit P1	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RPLP1			KEGG-&-1&-hsa03010-&&-Ribosome	RPLP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPLP1	0.493538462	0.41494508	0.38695652	118	4	0.034652375	FALSE	51.13333333	RPLP1	RPLP1	183.4396552	53.34274948	0	117	0	0.76500709	FALSE	1	RPLP1	355800	Infinity	0.05016317
788278	taxon:9606	2.33338585	400.5157621	1.09E-04	177957	1902	ribosomal protein S12	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS12			KEGG-&-1&-hsa03010-&&-Ribosome	RPS12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS12	0.504085481	0.42856178	0.50398378	118	4	0.041039836	FALSE	61.64285714	RPS12	RPS12	224.9067797	64.55968526	0	118	0	0.77776902	FALSE	0	RPS12	322938	Infinity	0.05442844
793108	taxon:9606	2.39435954	790.4925465	2.79E-04	180717	1902	lysine acetyltransferase 2A	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0021537-&&-telencephalon development-%%-GO:0048312-&&-intracellular distribution of mitochondria-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0001843-&&-neural tube closure-%%-GO:0030901-&&-midbrain development-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0071929-&&-alpha-tubulin acetylation-%%-GO:0016032-&&-viral process-%%-GO:0043983-&&-histone H4-K12 acetylation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0022037-&&-metencephalon development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0001756-&&-somitogenesis-%%-GO:0016578-&&-histone deubiquitination-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0031346-&&-positive regulation of cell projection organization-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0044154-&&-histone H3-K14 acetylation|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0030914-&&-STAGA complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0005615-&&-extracellular space-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0010484-&&-H3 histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0043997-&&-histone acetyltransferase activity (H4-K12 specific)-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:KAT2A			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	KAT2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT2A	0.492628993	0.41764822	0.15742129	118	4	0.020647535	FALSE	21.89534884	KAT2A	KAT2A	167.6637931	24.29150693	0	117	0	0.76760674	FALSE	1	KAT2A	602922	Infinity	0.04458456
789470	taxon:9606	2.24011344	1085.096814	2.69E-04	175394	1902	RNA binding motif protein 39	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0008380-&&-RNA splicing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016607-&&-nuclear speck-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM39				RBM39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM39	0.512460064	0.44640596	0.20367956	118	4	0.028467713	FALSE	26.22330097	RBM39	RBM39	215.6864407	30.29388773	0	118	0	0.79331443	FALSE	0	RBM39	626986	Infinity	0.0456866
790533	taxon:9606	2.32078147	1205.049305	4.10E-04	172560	1902	RNA binding motif protein, X-linked	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0044530-&&-supraspliceosomal complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0042802-&&-identical protein binding	G:9606:RBMX			KEGG-&-1&-hsa03040-&&-Spliceosome	RBMX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBMX	0.505993691	0.43088934	0.18169336	117	4	0.026409751	FALSE	25.78021978	RBMX	RBMX	197.2086957	28.19022293	0	116	0	0.77986975	FALSE	1	RBMX	718356	Infinity	0.04681655
791069	taxon:9606	2.37308965	904.8378945	5.78E-04	170152	1902	replication timing regulatory factor 1	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0000723-&&-telomere maintenance-%%-GO:0043247-&&-telomere maintenance in response to DNA damage-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:2001034-&&-positive regulation of double-strand break repair via nonhomologous end joining-%%-GO:0006348-&&-chromatin silencing at telomere-%%-GO:0007049-&&-cell cycle-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005886-&&-plasma membrane-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0031965-&&-nuclear membrane-%%-GO:0051233-&&-spindle midzone-%%-GO:0016604-&&-nuclear body-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001940-&&-male pronucleus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001939-&&-female pronucleus	G:9606:RIF1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	RIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIF1	0.487241798	0.42139158	0.0375286	117	4	0.011198902	FALSE	7.852459016	RIF1	RIF1	111.1565217	8.543341972	0	116	0	0.77115173	FALSE	1	RIF1	831654	Infinity	0.02857719
791535	taxon:9606	2.35134709	732.1834825	5.88E-04	168218	1902	SMAD specific E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:1901165-&&-positive regulation of trophoblast cell migration-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0046332-&&-SMAD binding	G:9606:SMURF2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04350-&&-TGF-beta signaling pathway	SMURF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMURF2	0.488131467	0.42528813	0.0617849	117	4	0.009832161	FALSE	11.04761905	SMURF2	SMURF2	106.373913	11.87601856	0	116	0	0.77477548	FALSE	1	SMURF2	730654	Infinity	0.0264067
787464	taxon:9606	2.40081928	428.3320135	6.91E-04	179394	1902	MET proto-oncogene, receptor tyrosine kinase	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:1901299-&&-negative regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0001886-&&-endothelial cell morphogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:2001028-&&-positive regulation of endothelial cell chemotaxis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0009925-&&-basal plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005008-&&-hepatocyte growth factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:MET	MET	TRUE	KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05144-&&-Malaria-%%-hsa05226-&&-Gastric cancer	MET	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MET	0.464658169	0.41652448	0.1006865	117	4	0.006941862	FALSE	15.49090909	MET	MET	96.25217391	16.99165181	0	116	0	0.76653012	FALSE	1	MET	781654	Infinity	0.02597662
787897	taxon:9606	2.25366315	924.4286285	3.04E-04	178646	1902	proteasome 26S subunit, non-ATPase 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity	G:9606:PSMD1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD1	0.509206349	0.44372204	0.24344238	117	4	0.020123143	FALSE	31.02083333	PSMD1	PSMD1	181.1538462	37.27038304	0	117	0	0.79105614	FALSE	0	PSMD1	637870	Infinity	0.03908389
791984	taxon:9606	2.38002206	1152.300287	5.73E-04	182775	1902	X-linked inhibitor of apoptosis	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0070424-&&-regulation of nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030510-&&-regulation of BMP signaling pathway-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0055070-&&-copper ion homeostasis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1902530-&&-positive regulation of protein linear polyubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:XIAP	XIAP	TRUE	KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05222-&&-Small cell lung cancer	XIAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XIAP	0.488875343	0.42016417	0.08039664	117	4	0.00960438	FALSE	13.06849315	XIAP	XIAP	107.1217391	15.63816842	0	116	0	0.76999632	FALSE	1	XIAP	725176	Infinity	0.02787091
787950	taxon:9606	2.27729636	840.308871	4.09E-04	178520	1902	p21 (RAC1) activated kinase 1	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006915-&&-apoptotic process-%%-GO:0021549-&&-cerebellum development-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0061052-&&-negative regulation of cell growth involved in cardiac muscle cell development-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0007409-&&-axonogenesis-%%-GO:0042060-&&-wound healing-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0060244-&&-negative regulation of cell proliferation involved in contact inhibition-%%-GO:0006887-&&-exocytosis-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071437-&&-invadopodium-%%-GO:0030424-&&-axon-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0043234-&&-protein complex-%%-GO:0030425-&&-dendrite-%%-GO:0001726-&&-ruffle-%%-GO:0005911-&&-cell-cell junction-%%-GO:0031965-&&-nuclear membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0030027-&&-lamellipodium-%%-GO:0030018-&&-Z disc-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding	G:9606:PAK1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04660-&&-T cell receptor signaling pathway	PAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK1	0.499844188	0.4391172	0.11395881	117	4	0.019760372	FALSE	17.63414634	PAK1	PAK1	179.2347826	18.76844187	0	116	0	0.78711727	FALSE	1	PAK1	877802	Infinity	0.0399465
787939	taxon:9606	2.23948322	1049.494686	6.33E-04	178537	1902	prolyl 4-hydroxylase subunit beta	gene	biological_process-&-1&-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006457-&&-protein folding-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0018401-&&-peptidyl-proline hydroxylation to 4-hydroxy-L-proline-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1902175-&&-regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0046598-&&-positive regulation of viral entry into host cell|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0016222-&&-procollagen-proline 4-dioxygenase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004656-&&-procollagen-proline 4-dioxygenase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:P4HB			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	P4HB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P4HB	0.505834122	0.44653159	0.12814645	117	4	0.020960983	FALSE	18.98795181	P4HB	P4HB	192.7217391	21.81831178	0	116	0	0.79341946	FALSE	1	P4HB	969684	Infinity	0.04082719
792186	taxon:9606	2.37088388	769.9699186	6.50E-04	182466	1902	ras homolog family member A	gene	biological_process-&-1&-GO:0036089-&&-cleavage furrow formation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0033688-&&-regulation of osteoblast proliferation-%%-GO:0060193-&&-positive regulation of lipase activity-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0043931-&&-ossification involved in bone maturation-%%-GO:0050919-&&-negative chemotaxis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043297-&&-apical junction assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097498-&&-endothelial tube lumen extension-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1903673-&&-mitotic cleavage furrow formation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0016032-&&-viral process-%%-GO:0061383-&&-trabecula morphogenesis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030168-&&-platelet activation-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:1902766-&&-skeletal muscle satellite cell migration-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0016477-&&-cell migration-%%-GO:0035385-&&-Roundabout signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0038027-&&-apolipoprotein A-I-mediated signaling pathway-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0090307-&&-mitotic spindle assembly|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0043296-&&-apical junction complex-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030027-&&-lamellipodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0005938-&&-cell cortex-%%-GO:0071944-&&-cell periphery-%%-GO:0005925-&&-focal adhesion-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005768-&&-endosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0017022-&&-myosin binding	G:9606:RHOA			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa05133-&&-Pertussis-%%-hsa04022-&&-cGMP-PKG signaling pathway	RHOA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOA	0.48902439	0.42178363	0.05293669	117	4	0.010195953	FALSE	10.19672131	RHOA	RHOA	103.6869565	11.0866116	0	116	0	0.77151935	FALSE	1	RHOA	770356	Infinity	0.02662792
788538	taxon:9606	2.23066015	1101.683284	4.30E-04	177472	1902	spectrin beta, non-erythrocytic 1	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:1900042-&&-positive regulation of interleukin-2 secretion-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007411-&&-axon guidance-%%-GO:0051693-&&-actin filament capping-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0043001-&&-Golgi to plasma membrane protein transport-%%-GO:1903076-&&-regulation of protein localization to plasma membrane-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007009-&&-plasma membrane organization-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071709-&&-membrane assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0014069-&&-postsynaptic density-%%-GO:0008091-&&-spectrin-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0014731-&&-spectrin-associated cytoskeleton-%%-GO:0032437-&&-cuticular plate-%%-GO:0030673-&&-axolemma-%%-GO:0043234-&&-protein complex-%%-GO:0031430-&&-M band|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0003779-&&-actin binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0030506-&&-ankyrin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding	G:9606:SPTBN1				SPTBN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPTBN1	0.507755619	0.44829778	0.12437371	117	4	0.024426645	FALSE	17.59782609	SPTBN1	SPTBN1	218.0854701	19.72144696	0	117	0	0.79488997	FALSE	0	SPTBN1	957300	Infinity	0.04566519
788599	taxon:9606	2.42193162	860.3674632	5.81E-04	177365	1902	transcription factor 3	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030183-&&-B cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033152-&&-immunoglobulin V(D)J recombination-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0002326-&&-B cell lineage commitment|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0070644-&&-vitamin D response element binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:TCF3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	TCF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF3	0.486650485	0.41289357	0.04912281	117	4	0.012247847	FALSE	8.560606061	TCF3	TCF3	101.5217391	9.498362789	0	116	0	0.7630114	FALSE	1	TCF3	791288	Infinity	0.02843832
790053	taxon:9606	2.3366945	1167.129812	4.31E-04	173998	1902	Fas associated factor 1	gene	biological_process-&-1&-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0008219-&&-cell death-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0045859-&&-regulation of protein kinase activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005634-&&-nucleus-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019887-&&-protein kinase regulator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:FAF1			KEGG-&-1&-hsa04217-&&-Necroptosis	FAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAF1	0.502506266	0.42795496	0.10114416	117	4	0.017555892	FALSE	14.27380952	FAF1	FAF1	150.8173913	16.57244418	0	116	0	0.77721758	FALSE	1	FAF1	721622	Infinity	0.03674252
790774	taxon:9606	2.42413739	793.5657216	3.61E-04	154878	1902	NME1-NME2 readthrough	gene		G:9606:NME1-NME2			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME1-NME2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME1-NME2	0.491421569	0.41251787	0.08461419	116	4	0.011894491	FALSE	12.78082192	NME1-NME2	NME1-NME2	109.754386	14.7776201	0	115	0	0.76264377	FALSE	1	NME1-NME2	636122	Infinity	0.03076938
787620	taxon:9606	2.42413739	793.5657216	3.61E-04	179078	1902	NME/NM23 nucleoside diphosphate kinase 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0006228-&&-UTP biosynthetic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0018106-&&-peptidyl-histidine phosphorylation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0002762-&&-negative regulation of myeloid leukocyte differentiation-%%-GO:0006183-&&-GTP biosynthetic process-%%-GO:0051259-&&-protein oligomerization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0060416-&&-response to growth hormone-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007155-&&-cell adhesion-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0045682-&&-regulation of epidermis development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006241-&&-CTP biosynthetic process-%%-GO:0009142-&&-nucleoside triphosphate biosynthetic process-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005882-&&-intermediate filament-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008144-&&-drug binding-%%-GO:0005515-&&-protein binding-%%-GO:0004550-&&-nucleoside diphosphate kinase activity-%%-GO:0004673-&&-protein histidine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019215-&&-intermediate filament binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:NME2			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME2	0.491421569	0.41251787	0.08461419	116	4	0.011894491	FALSE	12.78082192	NME2	NME2	109.754386	14.7776201	0	115	0	0.76264377	FALSE	1	NME2	636122	Infinity	0.03076938
787874	taxon:9606	2.38695447	1503.630763	2.70E-04	178664	1902	proteasome subunit beta 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB1			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB1	0.496287129	0.41894389	0.20464768	116	4	0.015700445	FALSE	25.35789474	PSMB1	PSMB1	134.3534483	31.25202979	0	116	0	0.76884092	FALSE	0	PSMB1	497272	Infinity	0.03538661
788821	taxon:9606	2.30833465	980.5859885	6.25E-04	176808	1902	ubiquitin conjugating enzyme E2 L3	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0044770-&&-cell cycle phase transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0008283-&&-cell proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2L3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease	UBE2L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2L3	0.50062422	0.43321275	0.08228536	116	4	0.013325107	FALSE	13.45333333	UBE2L3	UBE2L3	137	15.33501705	0	115	0	0.78194423	FALSE	1	UBE2L3	830082	Infinity	0.03193531
789026	taxon:9606	2.30171735	1308.616836	3.15E-04	176345	1902	structural maintenance of chromosomes 1A	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0009314-&&-response to radiation-%%-GO:0051301-&&-cell division-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008278-&&-cohesin complex-%%-GO:0030893-&&-meiotic cohesin complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0036033-&&-mediator complex binding	G:9606:SMC1A			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis	SMC1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC1A	0.50471995	0.43445821	0.15339233	116	4	0.023161074	FALSE	20.84615385	SMC1A	SMC1A	203.7192983	23.87586793	0	115	0	0.78304711	FALSE	1	SMC1A	732856	Infinity	0.04685155
787548	taxon:9606	2.34583268	1056.136961	5.36E-04	179209	1902	moesin	gene	biological_process-&-1&-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1902966-&&-positive regulation of protein localization to early endosome-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0071394-&&-cellular response to testosterone stimulus-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0050900-&&-leukocyte migration-%%-GO:2000401-&&-regulation of lymphocyte migration-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:1902115-&&-regulation of organelle assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0008361-&&-regulation of cell size|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0031528-&&-microvillus membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0045177-&&-apical part of cell-%%-GO:0001931-&&-uropod-%%-GO:0031143-&&-pseudopodium-%%-GO:0030175-&&-filopodium-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0072562-&&-blood microparticle-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0005102-&&-receptor binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:MSN			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSN	0.49844624	0.42628786	0.10493047	115	4	0.014587696	FALSE	14.88311688	MSN	MSN	138.1238938	17.84131066	0	114	0	0.77569455	FALSE	1	MSN	799982	Infinity	0.03405607
791919	taxon:9606	2.39026312	366.5998338	0.00127717	182873	1902	albumin	gene	biological_process-&-1&-GO:0019836-&&-hemolysis by symbiont of host erythrocytes-%%-GO:0001895-&&-retina homeostasis-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0051659-&&-maintenance of mitochondrion location-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006810-&&-transport-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0043252-&&-sodium-independent organic anion transport-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0043234-&&-protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016209-&&-antioxidant activity-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0015643-&&-toxic substance binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0008144-&&-drug binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019825-&&-oxygen binding-%%-GO:0003677-&&-DNA binding	G:9606:ALB	ALB	TRUE	KEGG-&-1&-hsa04918-&&-Thyroid hormone synthesis	ALB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALB	0.475400119	0.41836398	0.03255373	115	4	0.007999517	FALSE	6.575	ALB	ALB	88.39823009	6.793980529	0	114	0	0.76828948	FALSE	1	ALB	1197084	Infinity	0.02353194
787875	taxon:9606	2.28485899	885.3167045	4.16E-04	178667	1902	proteasome subunit alpha 5	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA5			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA5	0.505834122	0.43766377	0.2317315	115	4	0.018282639	FALSE	30.36363636	PSMA5	PSMA5	168.4695652	35.27531427	0	115	0	0.78585684	FALSE	0	PSMA5	724490	Infinity	0.03798245
792338	taxon:9606	2.34394202	789.4748161	2.65E-04	182210	1902	chromodomain helicase DNA binding protein 4	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0051225-&&-spindle assembly-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0072553-&&-terminal button organization-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0016581-&&-NuRD complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:CHD4			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	CHD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD4	0.502034429	0.42663171	0.16466498	115	4	0.022589799	FALSE	22.57471264	CHD4	CHD4	201.5663717	25.07557607	0	114	0	0.77600966	FALSE	1	CHD4	679216	Infinity	0.04936289
788427	taxon:9606	2.29273673	1813.353661	3.03E-04	177691	1902	serine and arginine rich splicing factor 2	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SRSF2			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF2	0.508883249	0.43615998	0.13147914	115	4	0.022140941	FALSE	18.38947368	SRSF2	SRSF2	189.9292035	20.88535997	0	114	0	0.78454388	FALSE	1	SRSF2	698752	Infinity	0.04321863
793283	taxon:9606	2.4195683	652.267876	1.47E-04	180376	1902	H3 histone family member 3A	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0031508-&&-pericentric heterochromatin assembly-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1902340-&&-negative regulation of chromosome condensation-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0007286-&&-spermatid development-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0090230-&&-regulation of centromere complex assembly-%%-GO:0008584-&&-male gonad development-%%-GO:0048477-&&-oogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007566-&&-embryo implantation-%%-GO:0031509-&&-telomeric heterochromatin assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0009725-&&-response to hormone-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007338-&&-single fertilization-%%-GO:0032200-&&-telomere organization-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0001740-&&-Barr body-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:H3F3A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	H3F3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H3F3A	0.493083308	0.41329687	0.16018307	115	4	0.021428278	FALSE	20.92134831	H3F3A	H3F3A	152.1565217	23.34538185	0	115	0	0.76340528	FALSE	0	H3F3A	475126	Infinity	0.04226778
793286	taxon:9606	2.4195683	652.267876	1.47E-04	180375	1902	H3 histone family member 3B	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0031508-&&-pericentric heterochromatin assembly-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1902340-&&-negative regulation of chromosome condensation-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0007286-&&-spermatid development-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0090230-&&-regulation of centromere complex assembly-%%-GO:0008584-&&-male gonad development-%%-GO:0048477-&&-oogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007566-&&-embryo implantation-%%-GO:0031509-&&-telomeric heterochromatin assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0009725-&&-response to hormone-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007338-&&-single fertilization-%%-GO:0032200-&&-telomere organization-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0001740-&&-Barr body-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:H3F3B			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	H3F3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H3F3B	0.493083308	0.41329687	0.16018307	115	4	0.021428278	FALSE	20.92134831	H3F3B	H3F3B	152.1565217	23.34538185	0	115	0	0.76340528	FALSE	0	H3F3B	475126	Infinity	0.04226778
789921	taxon:9606	2.4195683	652.267876	1.47E-04	157977	1902	H3 histone, family 3A, pseudogene 4	gene		G:9606:H3F3AP4				H3F3AP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H3F3AP4	0.493083308	0.41329687	0.16018307	115	4	0.021428278	FALSE	20.92134831	H3F3AP4	H3F3AP4	152.1565217	23.34538185	0	115	0	0.76340528	FALSE	0	H3F3AP4	475126	Infinity	0.04226778
790910	taxon:9606	2.37860406	984.7811196	2.36E-04	170723	1902	sirtuin 6	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:0031648-&&-protein destabilization-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0061647-&&-histone H3-K9 modification-%%-GO:1902732-&&-positive regulation of chondrocyte proliferation-%%-GO:0031940-&&-positive regulation of chromatin silencing at telomere-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0003247-&&-post-embryonic cardiac muscle cell growth involved in heart morphogenesis-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:1905564-&&-positive regulation of vascular endothelial cell proliferation-%%-GO:1990619-&&-histone H3-K9 deacetylation-%%-GO:1905555-&&-positive regulation blood vessel branching-%%-GO:0006284-&&-base-excision repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1905549-&&-positive regulation of telomeric heterochromatin assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005724-&&-nuclear telomeric heterochromatin|molecular_function-&-1&-GO:0017136-&&-NAD-dependent histone deacetylase activity-%%-GO:0070403-&&-NAD+ binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0034979-&&-NAD-dependent protein deacetylase activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0046969-&&-NAD-dependent histone deacetylase activity (H3-K9 specific)-%%-GO:0003956-&&-NAD(P)+-protein-arginine ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:SIRT6			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05230-&&-Central carbon metabolism in cancer	SIRT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT6	0.500311915	0.42041465	0.05884179	114	4	0.016677003	FALSE	8.26744186	SIRT6	SIRT6	131.3859649	9.181351114	0	114	0	0.77023266	FALSE	0	SIRT6	448282	Infinity	0.034031
787436	taxon:9606	2.29053096	828.3980816	5.74E-04	179442	1902	galectin 3 binding protein	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007155-&&-cell adhesion-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006968-&&-cellular defense response-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0072562-&&-blood microparticle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005044-&&-scavenger receptor activity	G:9606:LGALS3BP				LGALS3BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS3BP	0.501563477	0.43658	0.14687902	114	4	0.022576503	FALSE	22.36144578	LGALS3BP	LGALS3BP	185.3214286	23.92212463	0	113	0	0.78491151	FALSE	1	LGALS3BP	829106	Infinity	0.04211996
791630	taxon:9606	2.5274933	733.0623107	2.48E-04	167738	1902	histone deacetylase 11	gene	biological_process-&-1&-GO:0014003-&&-oligodendrocyte development-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006325-&&-chromatin organization-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)	G:9606:HDAC11			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC11	0.473715298	0.39564892	0.06070486	114	4	0.014059457	FALSE	9.338028169	HDAC11	HDAC11	113.5526316	9.953294143	0	114	0	0.74541778	FALSE	0	HDAC11	455230	Infinity	0.03875293
787896	taxon:9606	2.33858516	887.5182298	2.08E-04	178647	1902	proteasome 26S subunit, ATPase 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005634-&&-nucleus-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC6			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC6	0.503610675	0.42760897	0.25273488	114	4	0.017871123	FALSE	31.62222222	PSMC6	PSMC6	161.125	36.63505077	0	113	0	0.77690247	FALSE	1	PSMC6	475888	Infinity	0.03924135
792220	taxon:9606	2.28218056	1274.131478	4.11E-04	182392	1902	ATPase Na+/K+ transporting subunit alpha 1	gene	biological_process-&-1&-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:0045822-&&-negative regulation of heart contraction-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:1903416-&&-response to glycoside-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0045823-&&-positive regulation of heart contraction-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0042493-&&-response to drug-%%-GO:1990573-&&-potassium ion import across plasma membrane-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:0045989-&&-positive regulation of striated muscle contraction-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0031947-&&-negative regulation of glucocorticoid biosynthetic process-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0016311-&&-dephosphorylation-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0010107-&&-potassium ion import-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086009-&&-membrane repolarization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005768-&&-endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030315-&&-T-tubule-%%-GO:0042470-&&-melanosome-%%-GO:0042383-&&-sarcolemma-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0016021-&&-integral component of membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005794-&&-Golgi apparatus-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031402-&&-sodium ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:1990239-&&-steroid hormone binding-%%-GO:0030506-&&-ankyrin binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0043531-&&-ADP binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:ATP1A1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04978-&&-Mineral absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04976-&&-Bile secretion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1A1	0.50062422	0.43817742	0.12063344	114	4	0.015198195	FALSE	14.05	ATP1A1	ATP1A1	159.7192983	16.93429903	0	114	0	0.78630324	FALSE	0	ATP1A1	799796	Infinity	0.0358256
788216	taxon:9606	2.31101308	975.4035128	3.62E-04	178060	1902	UPF1, RNA helicase and ATPase	gene	biological_process-&-1&-GO:0006449-&&-regulation of translational termination-%%-GO:0032201-&&-telomere maintenance via semi-conservative replication-%%-GO:0006260-&&-DNA replication-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0009048-&&-dosage compensation by inactivation of X chromosome-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006281-&&-DNA repair-%%-GO:0000294-&&-nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0000723-&&-telomere maintenance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol-%%-GO:0044530-&&-supraspliceosomal complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005524-&&-ATP binding	G:9606:UPF1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	UPF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPF1	0.503927113	0.43271066	0.15416861	114	4	0.023977295	FALSE	19.6746988	UPF1	UPF1	197.1491228	21.98493902	0	114	0	0.78149782	FALSE	0	UPF1	699148	Infinity	0.04603932
792568	taxon:9606	2.39435954	985.5562824	5.18E-04	181796	1902	cyclin A2	gene	biological_process-&-1&-GO:0071373-&&-cellular response to luteinizing hormone stimulus-%%-GO:0044843-&&-cell cycle G1/S phase transition-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0051301-&&-cell division-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0033762-&&-response to glucagon-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0044320-&&-cellular response to leptin stimulus-%%-GO:0016032-&&-viral process-%%-GO:0071314-&&-cellular response to cocaine-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0090102-&&-cochlea development-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0097124-&&-cyclin A2-CDK2 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0001939-&&-female pronucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0001940-&&-male pronucleus-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex|molecular_function-&-1&-GO:0097472-&&-cyclin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding	G:9606:CCNA2	CCNA2	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection	CCNA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNA2	0.489322758	0.41764822	0.10601673	114	4	0.011833643	FALSE	14.8028169	CCNA2	CCNA2	122.4375	16.9996276	0	113	0	0.76760674	FALSE	1	CCNA2	727602	Infinity	0.03250569
788495	taxon:9606	2.29557271	470.5059042	1.86E-04	177549	1902	small nuclear ribonucleoprotein D1 polypeptide	gene	biological_process-&-1&-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071010-&&-prespliceosome-%%-GO:0005634-&&-nucleus-%%-GO:0005685-&&-U1 snRNP-%%-GO:0000243-&&-commitment complex-%%-GO:0005686-&&-U2 snRNP-%%-GO:0097526-&&-spliceosomal tri-snRNP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0003723-&&-RNA binding	G:9606:SNRPD1			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa03040-&&-Spliceosome	SNRPD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPD1	0.506793049	0.43562114	0.25011644	114	4	0.029514365	FALSE	30.57894737	SNRPD1	SNRPD1	212.3947368	32.83760928	0	114	0	0.78407121	FALSE	0	SNRPD1	471984	Infinity	0.04850302
788561	taxon:9606	2.3018749	638.4321642	6.14E-04	177439	1902	spleen associated tyrosine kinase	gene	biological_process-&-1&-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0010543-&&-regulation of platelet activation-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0045087-&&-innate immune response-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032928-&&-regulation of superoxide anion generation-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002283-&&-neutrophil activation involved in immune response-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0045401-&&-positive regulation of interleukin-3 biosynthetic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0016032-&&-viral process-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043313-&&-regulation of neutrophil degranulation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0002250-&&-adaptive immune response-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0002554-&&-serotonin secretion by platelet-%%-GO:0045425-&&-positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0042991-&&-transcription factor import into nucleus-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0090237-&&-regulation of arachidonic acid secretion-%%-GO:0046638-&&-positive regulation of alpha-beta T cell differentiation-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0008283-&&-cell proliferation-%%-GO:0002281-&&-macrophage activation involved in immune response-%%-GO:0031623-&&-receptor internalization-%%-GO:0045588-&&-positive regulation of gamma-delta T cell differentiation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:0043366-&&-beta selection-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0019370-&&-leukotriene biosynthetic process-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0071226-&&-cellular response to molecule of fungal origin-%%-GO:0006954-&&-inflammatory response-%%-GO:0001945-&&-lymph vessel development-%%-GO:0002366-&&-leukocyte activation involved in immune response|cellular_component-&-1&-GO:0019815-&&-B cell receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0032009-&&-early phagosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005178-&&-integrin binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0035325-&&-Toll-like receptor binding	G:9606:SYK			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04611-&&-Platelet activation-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway	SYK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYK	0.494146642	0.43442847	0.14333977	114	4	0.011771148	FALSE	18.29577465	SYK	SYK	138.6875	20.48131892	0	113	0	0.78302085	FALSE	1	SYK	870136	Infinity	0.03200727
788826	taxon:9606	2.33858516	942.4325386	6.32E-04	176806	1902	ubiquitin conjugating enzyme E2 N	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0031058-&&-positive regulation of histone modification-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006301-&&-postreplication repair-%%-GO:0033182-&&-regulation of histone ubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007254-&&-JNK cascade|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0035370-&&-UBC13-UEV1A complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031372-&&-UBC13-MMS2 complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2N			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2N	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2N	0.496133622	0.42760897	0.07351995	114	4	0.012349044	FALSE	12.11594203	UBE2N	UBE2N	129.375	13.89641491	0	113	0	0.77690247	FALSE	1	UBE2N	872360	Infinity	0.03152643
793226	taxon:9606	2.38774224	988.389243	6.16E-04	180497	1902	heat shock protein family E (Hsp10) member 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:HSPE1				HSPE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPE1	0.491722869	0.41880567	0.10448688	114	4	0.012629647	FALSE	12.44927536	HSPE1	HSPE1	123.0789474	14.15143356	0	114	0	0.76870963	FALSE	0	HSPE1	874836	Infinity	0.03242102
790248	taxon:9606	2.37245943	496.3549625	6.62E-04	173528	1902	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0007588-&&-excretion-%%-GO:0010038-&&-response to metal ion-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:0030104-&&-water homeostasis-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0019058-&&-viral life cycle-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:2001288-&&-positive regulation of caveolin-mediated endocytosis-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:0003254-&&-regulation of membrane depolarization-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:1902306-&&-negative regulation of sodium ion transmembrane transport-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019870-&&-potassium channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019871-&&-sodium channel inhibitor activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0017080-&&-sodium channel regulator activity	G:9606:NEDD4L			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04530-&&-Tight junction-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption	NEDD4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD4L	0.486650485	0.42150352	0.0453668	114	4	0.008821951	FALSE	9.903846154	NEDD4L	NEDD4L	106.6964286	10.5534384	0	113	0	0.77125676	FALSE	1	NEDD4L	838268	Infinity	0.02747182
787435	taxon:9606	2.31243107	540.6298587	0.00161204	179443	1902	galectin 3	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:2000521-&&-negative regulation of immunological synapse formation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0070232-&&-regulation of T cell apoptotic process-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0008380-&&-RNA splicing-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0006397-&&-mRNA processing-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0071674-&&-mononuclear cell migration-%%-GO:2001189-&&-negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell-%%-GO:0050918-&&-positive chemotaxis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0043236-&&-laminin binding-%%-GO:0019863-&&-IgE binding	G:9606:LGALS3	LGALS3	TRUE		LGALS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS3	0.489920586	0.43244532	0.03521704	113	4	0.010122978	FALSE	7.803571429	LGALS3	LGALS3	102.5765766	8.163511299	0	112	0	0.78126149	FALSE	1	LGALS3	1539504	Infinity	0.02411241
787946	taxon:9606	2.25712935	1077.599601	4.41E-04	178524	1902	peroxiredoxin 1	gene	biological_process-&-1&-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0001895-&&-retina homeostasis-%%-GO:0042345-&&-regulation of NF-kappaB import into nucleus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0001501-&&-skeletal system development-%%-GO:0008283-&&-cell proliferation-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0034101-&&-erythrocyte homeostasis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0004601-&&-peroxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:PRDX1			KEGG-&-1&-hsa04146-&&-Peroxisome	PRDX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX1	0.504878816	0.44304063	0.11875512	113	4	0.023825545	FALSE	16.04651163	PRDX1	PRDX1	215.1261261	18.02778679	0	112	0	0.79047844	FALSE	1	PRDX1	836800	Infinity	0.0466351
788168	taxon:9606	2.36773279	1380.209755	3.34E-04	178138	1902	RAD23 homolog B, nucleotide excision repair protein	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006457-&&-protein folding-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0048568-&&-embryonic organ development-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0071942-&&-XPC complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:RAD23B			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RAD23B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD23B	0.500780518	0.42234496	0.11472819	113	4	0.01668182	FALSE	15.26436782	RAD23B	RAD23B	156.6902655	17.58213302	0	113	0	0.77204454	FALSE	0	RAD23B	670960	Infinity	0.03988834
788295	taxon:9606	2.46431385	1745.34538	1.44E-04	177937	1902	ribosomal protein S28	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS28			KEGG-&-1&-hsa03010-&&-Ribosome	RPS28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS28	0.490220049	0.40579247	0.42541087	113	4	0.036584087	FALSE	50.48113208	RPS28	RPS28	200.3982301	53.42917794	0	113	0	0.75594769	FALSE	0	RPS28	391684	Infinity	0.06023391
788289	taxon:9606	2.38758469	529.1224524	1.01E-04	177944	1902	ribosomal protein S21	gene	biological_process-&-1&-GO:0000461-&&-endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0000447-&&-endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0047485-&&-protein N-terminus binding	G:9606:RPS21			KEGG-&-1&-hsa03010-&&-Ribosome	RPS21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS21	0.49644073	0.41883331	0.4522756	113	4	0.038291387	FALSE	53.74766355	RPS21	RPS21	214.2389381	55.54928265	0	113	0	0.76873589	FALSE	0	RPS21	285178	Infinity	0.05658247
792485	taxon:9606	2.26091067	499.2531946	8.97E-04	181947	1902	cyclin D1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0051412-&&-response to corticosterone-%%-GO:0097421-&&-liver regeneration-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051301-&&-cell division-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0007595-&&-lactation-%%-GO:0043627-&&-response to estrogen-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0045471-&&-response to ethanol-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation-%%-GO:0070141-&&-response to UV-A-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010165-&&-response to X-ray-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0042493-&&-response to drug-%%-GO:0051592-&&-response to calcium ion-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000320-&&-re-entry into mitotic cell cycle-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0033197-&&-response to vitamin E-%%-GO:0032355-&&-response to estradiol-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0044321-&&-response to leptin-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0010039-&&-response to iron ion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0016020-&&-membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:CCND1	CCND1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	CCND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCND1	0.503768844	0.44229965	0.1022113	113	4	0.015737081	FALSE	17.42647059	CCND1	CCND1	161.5765766	18.49897707	0	112	0	0.78984822	FALSE	1	CCND1	1083832	Infinity	0.03526103
788430	taxon:9606	2.32093903	731.5794113	1.97E-04	177686	1902	serine and arginine rich splicing factor 7	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SRSF7			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF7	0.506953224	0.43086009	0.22771808	113	4	0.028537214	FALSE	27.13131313	SRSF7	SRSF7	217.1238938	31.09086169	0	113	0	0.7798435	FALSE	0	SRSF7	510648	Infinity	0.05153665
788441	taxon:9606	2.33354341	1129.316217	2.83E-04	177671	1902	SKI proto-oncogene	gene	biological_process-&-1&-GO:0032926-&&-negative regulation of activin receptor signaling pathway-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060325-&&-face morphogenesis-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031064-&&-negative regulation of histone deacetylation-%%-GO:0010626-&&-negative regulation of Schwann cell proliferation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0043585-&&-nose morphogenesis-%%-GO:0014902-&&-myotube differentiation-%%-GO:0048870-&&-cell motility-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0060021-&&-palate development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0001843-&&-neural tube closure-%%-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0043010-&&-camera-type eye development-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0048666-&&-neuron development-%%-GO:0008283-&&-cell proliferation-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0046811-&&-histone deacetylase inhibitor activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:SKI	SKI	TRUE		SKI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKI	0.501877347	0.42853285	0.09107289	113	4	0.019322339	FALSE	13.64772727	SKI	SKI	148.2342342	15.42479173	0	112	0	0.77774277	FALSE	1	SKI	521608	Infinity	0.03582693
788691	taxon:9606	2.48889239	243.6631787	0.00302892	177174	1902	tumor necrosis factor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0007254-&&-JNK cascade-%%-GO:0060664-&&-epithelial cell proliferation involved in salivary gland morphogenesis-%%-GO:0031622-&&-positive regulation of fever generation-%%-GO:0035509-&&-negative regulation of myosin-light-chain-phosphatase activity-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0002925-&&-positive regulation of humoral immune response mediated by circulating immunoglobulin-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:2000334-&&-positive regulation of blood microparticle formation-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:2000343-&&-positive regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0043242-&&-negative regulation of protein complex disassembly-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0060559-&&-positive regulation of calcidiol 1-monooxygenase activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009615-&&-response to virus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1904999-&&-positive regulation of leukocyte adhesion to arterial endothelial cell-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0061048-&&-negative regulation of branching involved in lung morphogenesis-%%-GO:0045994-&&-positive regulation of translational initiation by iron-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060557-&&-positive regulation of vitamin D biosynthetic process-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0060693-&&-regulation of branching involved in salivary gland morphogenesis-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0006954-&&-inflammatory response-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:1901671-&&-positive regulation of superoxide dismutase activity-%%-GO:0051798-&&-positive regulation of hair follicle development-%%-GO:0006959-&&-humoral immune response-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:0002740-&&-negative regulation of cytokine secretion involved in immune response-%%-GO:0043243-&&-positive regulation of protein complex disassembly-%%-GO:0051222-&&-positive regulation of protein transport-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0032800-&&-receptor biosynthetic process-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:0009651-&&-response to salt stress-%%-GO:1904996-&&-positive regulation of leukocyte adhesion to vascular endothelial cell-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0002439-&&-chronic inflammatory response to antigenic stimulus-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:1903347-&&-negative regulation of bicellular tight junction assembly-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0010693-&&-negative regulation of alkaline phosphatase activity-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002876-&&-positive regulation of chronic inflammatory response to antigenic stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0030730-&&-sequestering of triglyceride-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0055037-&&-recycling endosome-%%-GO:0001891-&&-phagocytic cup-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0002020-&&-protease binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding	G:9606:TNF	TNF	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05330-&&-Allograft rejection-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa05134-&&-Legionellosis-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05310-&&-Asthma-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	TNF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNF	0.457370972	0.40178515	0.03898444	113	4	0.005415299	FALSE	11.45	TNF	TNF	65.88288288	11.83930469	0	112	0	0.75185127	FALSE	1	TNF	3476808	Infinity	0.02107615
788899	taxon:9606	2.28958563	911.5101738	4.54E-04	176651	1902	YY1 transcription factor	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0010225-&&-response to UV-C-%%-GO:0030154-&&-cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0007283-&&-spermatogenesis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0034644-&&-cellular response to UV|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus-%%-GO:0031011-&&-Ino80 complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding	G:9606:YY1				YY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YY1	0.501877347	0.43676025	0.11384111	113	4	0.016298402	FALSE	16.28571429	YY1	YY1	162.3513514	17.63860485	0	112	0	0.78506906	FALSE	1	YY1	756166	Infinity	0.03677063
793081	taxon:9606	2.23680479	1354.017943	5.31E-04	180785	1902	mechanistic target of rapamycin	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1904193-&&-negative regulation of cholangiocyte apoptotic process-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0014736-&&-negative regulation of muscle atrophy-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0051534-&&-negative regulation of NFAT protein import into nucleus-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0032868-&&-response to insulin-%%-GO:1904000-&&-positive regulation of eating behavior-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0031929-&&-TOR signaling-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0042060-&&-wound healing-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007584-&&-response to nutrient-%%-GO:0031295-&&-T cell costimulation-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0042220-&&-response to cocaine-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:0007165-&&-signal transduction-%%-GO:1904197-&&-positive regulation of granulosa cell proliferation-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0007569-&&-cell aging-%%-GO:0016049-&&-cell growth-%%-GO:0016310-&&-phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0043200-&&-response to amino acid-%%-GO:0030163-&&-protein catabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0055013-&&-cardiac muscle cell development-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0045727-&&-positive regulation of translation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0032095-&&-regulation of response to food-%%-GO:0016236-&&-macroautophagy-%%-GO:0043276-&&-anoikis-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0007616-&&-long-term memory-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0007281-&&-germ cell development-%%-GO:1904058-&&-positive regulation of sensory perception of pain-%%-GO:0031641-&&-regulation of myelination-%%-GO:0021510-&&-spinal cord development-%%-GO:0031998-&&-regulation of fatty acid beta-oxidation-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0003179-&&-heart valve morphogenesis-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0035176-&&-social behavior-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:1904056-&&-positive regulation of cholangiocyte proliferation-%%-GO:0043610-&&-regulation of carbohydrate utilization-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0007420-&&-brain development-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0040007-&&-growth-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0031529-&&-ruffle organization-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0090559-&&-regulation of membrane permeability-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043278-&&-response to morphine-%%-GO:1904213-&&-negative regulation of iodide transmembrane transport-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0008542-&&-visual learning-%%-GO:0009791-&&-post-embryonic development-%%-GO:0006950-&&-response to stress-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0050882-&&-voluntary musculoskeletal movement-%%-GO:1904206-&&-positive regulation of skeletal muscle hypertrophy-%%-GO:0060135-&&-maternal process involved in female pregnancy|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0031931-&&-TORC1 complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005764-&&-lysosome-%%-GO:0031932-&&-TORC2 complex-%%-GO:0012505-&&-endomembrane system-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001156-&&-TFIIIC-class transcription factor binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0001031-&&-RNA polymerase III type 2 promoter DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0001032-&&-RNA polymerase III type 3 promoter DNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001030-&&-RNA polymerase III type 1 promoter DNA binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:MTOR	MTOR	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04136-&&-Autophagy - other-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	MTOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTOR	0.507434356	0.44706628	0.0971335	113	4	0.015661143	FALSE	14.29761905	MTOR	MTOR	155.8288288	17.11553206	0	112	0	0.79386587	FALSE	1	MTOR	829252	Infinity	0.03286265
789404	taxon:9606	2.38805735	819.3695072	3.36E-04	175550	1902	COP9 signalosome subunit 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0008283-&&-cell proliferation-%%-GO:0022008-&&-neurogenesis-%%-GO:0000338-&&-protein deneddylation-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0030182-&&-neuron differentiation-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004871-&&-signal transducer activity	G:9606:COPS2				COPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS2	0.494298921	0.41875041	0.14791155	113	4	0.020759391	FALSE	20.45454545	COPS2	COPS2	175.1801802	22.39279037	0	112	0	0.76865711	FALSE	1	COPS2	685762	Infinity	0.04603
789867	taxon:9606	2.29510005	1671.545315	4.49E-04	174483	1902	inner membrane mitochondrial protein	gene	biological_process-&-1&-GO:0042407-&&-cristae formation-%%-GO:0008150-&&-biological_process-%%-GO:0051560-&&-mitochondrial calcium ion homeostasis|cellular_component-&-1&-GO:0043209-&&-myelin sheath-%%-GO:0061617-&&-MICOS complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:IMMT				IMMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IMMT	0.500780518	0.43571085	0.08239148	113	4	0.015484002	FALSE	11.6	IMMT	IMMT	160.2342342	13.8644546	0	112	0	0.78414999	FALSE	1	IMMT	833608	Infinity	0.03653734
790876	taxon:9606	2.35449819	986.4972605	3.62E-04	170793	1902	UBX domain protein 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1903094-&&-negative regulation of protein K48-linked deubiquitination-%%-GO:2000157-&&-negative regulation of ubiquitin-specific protease activity-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1904293-&&-negative regulation of ERAD pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0000502-&&-proteasome complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0071796-&&-K6-linked polyubiquitin binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:UBXN1				UBXN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN1	0.497672975	0.42471895	0.09090909	112	4	0.012967816	FALSE	13.23943662	UBXN1	UBXN1	131.8363636	15.09400049	0	111	0	0.7742503	FALSE	1	UBXN1	597930	Infinity	0.03289698
791304	taxon:9606	2.44761305	1095.387838	0.00115424	169283	1902	ubiquilin 4	gene	biological_process-&-1&-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1901097-&&-negative regulation of autophagosome maturation-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBQLN4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UBQLN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBQLN4	0.474977791	0.40856131	0.03619683	112	4	0.006432343	FALSE	7.611111111	UBQLN4	UBQLN4	76.50909091	8.428375463	0	111	0	0.75873116	FALSE	1	UBQLN4	1195086	Infinity	0.02255653
787330	taxon:9606	2.25350559	905.9349861	5.91E-04	179656	1902	keratin 18	gene	biological_process-&-1&-GO:0043000-&&-Golgi to plasma membrane CFTR protein transport-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0031424-&&-keratinization-%%-GO:0007049-&&-cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0070268-&&-cornification-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0045095-&&-keratin filament-%%-GO:0005730-&&-nucleolus-%%-GO:0034451-&&-centriolar satellite-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion	G:9606:KRT18	KRT18	TRUE	KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04915-&&-Estrogen signaling pathway	KRT18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT18	0.503136763	0.44375306	0.11943286	112	4	0.021642385	FALSE	17.675	KRT18	KRT18	202.5545455	19.11824356	0	111	0	0.7910824	FALSE	1	KRT18	977764	Infinity	0.043616
792520	taxon:9606	2.21143847	891.2972185	8.95E-04	181858	1902	calreticulin	gene	biological_process-&-1&-GO:0022417-&&-protein maturation by protein folding-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0002502-&&-peptide antigen assembly with MHC class I protein complex-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0042493-&&-response to drug-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0033574-&&-response to testosterone-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0032355-&&-response to estradiol-%%-GO:0033144-&&-negative regulation of intracellular steroid hormone receptor signaling pathway-%%-GO:1990668-&&-vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:2000510-&&-positive regulation of dendritic cell chemotaxis-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0006457-&&-protein folding-%%-GO:0090398-&&-cellular senescence-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0050821-&&-protein stabilization-%%-GO:0051208-&&-sequestering of calcium ion-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0034504-&&-protein localization to nucleus|cellular_component-&-1&-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005844-&&-polysome-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0033018-&&-sarcoplasmic reticulum lumen-%%-GO:0042824-&&-MHC class I peptide loading complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0042562-&&-hormone binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0005178-&&-integrin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001849-&&-complement component C1q binding-%%-GO:0042277-&&-peptide binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0008270-&&-zinc ion binding	G:9606:CALR			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CALR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALR	0.502034429	0.45219436	0.10692244	112	4	0.016649297	FALSE	16.23943662	CALR	CALR	177.9727273	17.93952471	0	111	0	0.79809359	FALSE	1	CALR	1192610	Infinity	0.03632281
788476	taxon:9606	2.35418308	2102.391426	4.50E-04	177575	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0022008-&&-neurogenesis-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0008080-&&-N-acetyltransferase activity	G:9606:SMARCE1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCE1	0.496902107	0.4247758	0.12162162	112	4	0.015304416	FALSE	14.6875	SMARCE1	SMARCE1	154.7410714	17.11198444	0	112	0	0.77430282	FALSE	0	SMARCE1	900786	Infinity	0.03855398
788640	taxon:9606	2.29194895	1322.78618	4.29E-04	177274	1902	ubiquitin like modifier activating enzyme 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0030867-&&-rough endoplasmic reticulum membrane-%%-GO:0000792-&&-heterochromatin-%%-GO:0010008-&&-endosome membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030057-&&-desmosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004839-&&-ubiquitin activating enzyme activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:UBA1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease	UBA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA1	0.504878816	0.43630989	0.09557965	112	4	0.016862635	FALSE	13.82926829	UBA1	UBA1	162.7454546	16.71451404	0	111	0	0.78467517	FALSE	1	UBA1	690806	Infinity	0.03701299
788843	taxon:9606	2.34536001	1466.404818	3.08E-04	176765	1902	ubiquinol-cytochrome c reductase core protein II	gene	biological_process-&-1&-GO:0006627-&&-protein processing involved in protein targeting to mitochondrion-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0009060-&&-aerobic respiration|cellular_component-&-1&-GO:0005750-&&-mitochondrial respiratory chain complex III-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:UQCRC2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	UQCRC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UQCRC2	0.494298921	0.42637377	0.1483269	112	4	0.014591901	FALSE	15.73809524	UQCRC2	UQCRC2	139.5267857	20.27280191	0	112	0	0.77577333	FALSE	0	UQCRC2	555196	Infinity	0.03427957
789666	taxon:9606	2.36253348	579.9003132	2.78E-04	174943	1902	tubulin gamma complex associated protein 3	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0051298-&&-centrosome duplication-%%-GO:0007338-&&-single fertilization-%%-GO:0031122-&&-cytoplasmic microtubule organization|cellular_component-&-1&-GO:0008275-&&-gamma-tubulin small complex-%%-GO:0005813-&&-centrosome-%%-GO:0005816-&&-spindle pole body-%%-GO:0005819-&&-spindle-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0016020-&&-membrane-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005827-&&-polar microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0043015-&&-gamma-tubulin binding	G:9606:TUBGCP3				TUBGCP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBGCP3	0.497827436	0.42327442	0.11872587	112	4	0.020270627	FALSE	16.77333333	TUBGCP3	TUBGCP3	149.4107143	17.71640453	0	112	0	0.77291109	FALSE	0	TUBGCP3	505246	Infinity	0.03772096
789747	taxon:9606	2.3067591	870.1898887	5.42E-04	174772	1902	ARP2 actin related protein 2 homolog	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0008306-&&-associative learning-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051653-&&-spindle localization-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0060271-&&-cilium assembly-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016482-&&-cytosolic transport-%%-GO:0033206-&&-meiotic cytokinesis-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0035984-&&-cellular response to trichostatin A-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0016344-&&-meiotic chromosome movement towards spindle pole|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0014069-&&-postsynaptic density-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030478-&&-actin cap-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane-%%-GO:0071437-&&-invadopodium-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding	G:9606:ACTR2			KEGG-&-1&-hsa04530-&&-Tight junction	ACTR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTR2	0.499221911	0.43350864	0.13819176	112	4	0.01509825	FALSE	15.67647059	ACTR2	ACTR2	162	17.52001889	0	112	0	0.78220682	FALSE	0	ACTR2	876862	Infinity	0.03767027
790861	taxon:9606	2.52780841	702.8571777	2.53E-04	170857	1902	anillin actin binding protein	gene	biological_process-&-1&-GO:0000921-&&-septin ring assembly-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0090521-&&-glomerular visceral epithelial cell migration|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005826-&&-actomyosin contractile ring|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0045296-&&-cadherin binding	G:9606:ANLN				ANLN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANLN	0.45841669	0.3955996	0.11809992	111	4	0.008253999	FALSE	13.609375	ANLN	ANLN	90.73873874	15.07298358	0	111	0	0.74536526	FALSE	0	ANLN	419208	Infinity	0.03103069
787682	taxon:9606	2.24893651	998.4469653	6.85E-04	178963	1902	phosphoinositide-3-kinase regulatory subunit 2	gene	biological_process-&-1&-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:PIK3R2			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R2	0.501720363	0.44465462	0.14594595	111	4	0.01534528	FALSE	18.70666667	PIK3R2	PIK3R2	164.9369369	22.15439425	0	111	0	0.79184392	FALSE	0	PIK3R2	961046	Infinity	0.03536949
787873	taxon:9606	2.23995588	773.8197262	4.49E-04	178665	1902	proteasome subunit alpha 7	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0098794-&&-postsynapse-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA7			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA7	0.507594937	0.44643736	0.26571526	111	4	0.018702451	FALSE	32.83333333	PSMA7	PSMA7	195.5412844	37.98703892	0	110	0	0.79334069	FALSE	1	PSMA7	783782	Infinity	0.04138246
792333	taxon:9606	2.40696392	652.1130125	3.68E-04	182214	1902	regulator of chromosome condensation 1	gene	biological_process-&-1&-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0007059-&&-chromosome segregation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051225-&&-spindle assembly-%%-GO:0016032-&&-viral process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0005087-&&-Ran guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:RCC1				RCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCC1	0.493083308	0.41546115	0.14780836	111	4	0.021730207	FALSE	22.25316456	RCC1	RCC1	175.2568807	23.48943111	0	110	0	0.76550601	FALSE	1	RCC1	712770	Infinity	0.04767446
788285	taxon:9606	2.38285804	407.8174129	1.81E-04	177954	1902	ribosomal protein S15	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0000056-&&-ribosomal small subunit export from nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS15			KEGG-&-1&-hsa03010-&&-Ribosome	RPS15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS15	0.49751861	0.41966411	0.47108927	111	4	0.034387883	FALSE	57.39393939	RPS15	RPS15	189.5495496	59.92781453	0	111	0	0.76952366	FALSE	0	RPS15	335316	Infinity	0.04938524
789593	taxon:9606	2.32960454	765.6228199	3.83E-04	175104	1902	SEC16 homolog A, endoplasmic reticulum export factor	gene	biological_process-&-1&-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0015031-&&-protein transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SEC16A				SEC16A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC16A	0.499377335	0.42925741	0.10532351	111	4	0.016270524	FALSE	12.52112676	SEC16A	SEC16A	160.972973	13.36910463	0	111	0	0.77839924	FALSE	0	SEC16A	670634	Infinity	0.03861467
789866	taxon:9606	2.30439578	875.4263854	2.32E-04	174480	1902	splicing factor 3b subunit 2	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SF3B2			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B2	0.505834122	0.43395323	0.17133497	111	4	0.026431186	FALSE	21.17894737	SF3B2	SF3B2	217.018018	23.19714464	0	111	0	0.7826007	FALSE	0	SF3B2	581784	Infinity	0.05021032
790615	taxon:9606	2.29399716	1385.330396	3.16E-04	171748	1902	ubiquitin protein ligase E3 component n-recognin 5	gene	biological_process-&-1&-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:2000780-&&-negative regulation of double-strand break repair-%%-GO:1901315-&&-negative regulation of histone H2A K63-linked ubiquitination-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0006281-&&-DNA repair-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:UBR5			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBR5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBR5	0.50519685	0.43592033	0.08566978	110	4	0.015228538	FALSE	13.01190476	UBR5	UBR5	159.4259259	15.35486641	0	109	0	0.78433381	FALSE	1	UBR5	646854	Infinity	0.036299
790875	taxon:9606	2.59524185	519.3339709	4.71E-04	170800	1902	golgi transport 1B	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0007165-&&-signal transduction-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity	G:9606:GOLT1B				GOLT1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLT1B	0.426482319	0.38532054	0.07122602	110	4	0.004374534	FALSE	7.729166667	GOLT1B	GOLT1B	59.45454545	8.60591307	0	110	0	0.73412636	FALSE	0	GOLT1B	489666	Infinity	0.02394392
787237	taxon:9606	2.28296833	876.8713069	5.87E-04	179816	1902	interleukin 1 receptor associated kinase 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0034605-&&-cellular response to heat-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0001959-&&-regulation of cytokine-mediated signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0034134-&&-toll-like receptor 2 signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0045323-&&-interleukin-1 receptor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:IRAK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05133-&&-Pertussis	IRAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRAK1	0.501877347	0.43802622	0.10903427	110	4	0.014692239	FALSE	15.55696203	IRAK1	IRAK1	150.8148148	17.30656654	0	109	0	0.78617194	FALSE	1	IRAK1	792108	Infinity	0.03380325
787262	taxon:9606	2.33448873	833.2656653	8.38E-04	179783	1902	Janus kinase 2	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045822-&&-negative regulation of heart contraction-%%-GO:1902728-&&-positive regulation of growth factor dependent skeletal muscle satellite cell proliferation-%%-GO:0042977-&&-activation of JAK2 kinase activity-%%-GO:0060399-&&-positive regulation of growth hormone receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0031103-&&-axon regeneration-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007260-&&-tyrosine phosphorylation of STAT protein-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007165-&&-signal transduction-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0070671-&&-response to interleukin-12-%%-GO:0002250-&&-adaptive immune response-%%-GO:1904037-&&-positive regulation of epithelial cell apoptotic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042506-&&-tyrosine phosphorylation of Stat5 protein-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:0031959-&&-mineralocorticoid receptor signaling pathway-%%-GO:0046677-&&-response to antibiotic-%%-GO:0035722-&&-interleukin-12-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0042503-&&-tyrosine phosphorylation of Stat3 protein-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0061180-&&-mammary gland epithelium development-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007498-&&-mesoderm development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0033194-&&-response to hydroperoxide-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0050867-&&-positive regulation of cell activation-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0035409-&&-histone H3-Y41 phosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042508-&&-tyrosine phosphorylation of Stat1 protein-%%-GO:0007596-&&-blood coagulation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola-%%-GO:0005925-&&-focal adhesion-%%-GO:0016363-&&-nuclear matrix-%%-GO:0045121-&&-membrane raft-%%-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0031904-&&-endosome lumen|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0020037-&&-heme binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0033130-&&-acetylcholine receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005131-&&-growth hormone receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0035401-&&-histone kinase activity (H3-Y41 specific)-%%-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005143-&&-interleukin-12 receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:JAK2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	JAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAK2	0.488428745	0.42835932	0.13049498	110	4	0.010134848	FALSE	16.51428571	JAK2	JAK2	124.8611111	19.29281058	0	109	0	0.77758521	FALSE	1	JAK2	1088356	Infinity	0.03022315
792141	taxon:9606	2.28564676	1143.327259	4.72E-04	182525	1902	actinin alpha 4	gene	biological_process-&-1&-GO:0030050-&&-vesicle transport along actin filament-%%-GO:0015031-&&-protein transport-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0051271-&&-negative regulation of cellular component movement-%%-GO:0048549-&&-positive regulation of pinocytosis-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0032417-&&-positive regulation of sodium:proton antiporter activity-%%-GO:1902396-&&-protein localization to bicellular tight junction-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0002576-&&-platelet degranulation-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051017-&&-actin filament bundle assembly|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0005829-&&-cytosol-%%-GO:0031143-&&-pseudopodium-%%-GO:0043234-&&-protein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0016604-&&-nuclear body-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005622-&&-intracellular-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003779-&&-actin binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005178-&&-integrin binding-%%-GO:0001882-&&-nucleoside binding-%%-GO:0044325-&&-ion channel binding	G:9606:ACTN4			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction	ACTN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTN4	0.503452605	0.43751292	0.11192661	110	4	0.01735422	FALSE	15.1125	ACTN4	ACTN4	171.0272727	17.80290942	0	110	0	0.78572554	FALSE	0	ACTN4	821422	Infinity	0.03857433
788147	taxon:9606	2.47392469	1002.297969	4.24E-04	178163	1902	RAB1A, member RAS oncogene family	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0019068-&&-virion assembly-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:1903020-&&-positive regulation of glycoprotein metabolic process-%%-GO:0072606-&&-interleukin-8 secretion-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0016477-&&-cell migration-%%-GO:0007030-&&-Golgi organization-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0006914-&&-autophagy-%%-GO:0060271-&&-cilium assembly-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0006897-&&-endocytosis-%%-GO:0090110-&&-cargo loading into COPII-coated vesicle-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0030252-&&-growth hormone secretion-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0032402-&&-melanosome transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005769-&&-early endosome-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0045296-&&-cadherin binding	G:9606:RAB1A			KEGG-&-1&-hsa05134-&&-Legionellosis	RAB1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB1A	0.476105669	0.40421602	0.08023353	110	4	0.009406046	FALSE	9.646153846	RAB1A	RAB1A	96.08181818	11.84789378	0	110	0	0.75434589	FALSE	0	RAB1A	560222	Infinity	0.02949241
788178	taxon:9606	2.283441	1035.075047	5.30E-04	178123	1902	RAN binding protein 2	gene	biological_process-&-1&-GO:0046604-&&-positive regulation of mitotic centrosome separation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007051-&&-spindle organization-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0019083-&&-viral transcription-%%-GO:0051642-&&-centrosome localization-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006457-&&-protein folding-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0006409-&&-tRNA export from nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm-%%-GO:0044614-&&-nuclear pore cytoplasmic filaments-%%-GO:0016020-&&-membrane-%%-GO:0005642-&&-annulate lamellae-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042405-&&-nuclear inclusion body|molecular_function-&-1&-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0019789-&&-SUMO transferase activity	G:9606:RANBP2			KEGG-&-1&-hsa03013-&&-RNA transport	RANBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP2	0.507916403	0.43793556	0.1472828	110	4	0.022715256	FALSE	19.94382022	RANBP2	RANBP2	195.2685185	22.14040711	0	109	0	0.78609317	FALSE	1	RANBP2	830752	Infinity	0.04376406
788443	taxon:9606	2.31526706	976.2190543	3.57E-04	177667	1902	S-phase kinase associated protein 2	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:1902916-&&-positive regulation of protein polyubiquitination-%%-GO:0071460-&&-cellular response to cell-matrix adhesion-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:SKP2			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05222-&&-Small cell lung cancer	SKP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKP2	0.500468019	0.43191562	0.11474559	110	4	0.013805047	FALSE	15.09333333	SKP2	SKP2	144.5	17.11993099	0	109	0	0.78078882	FALSE	1	SKP2	602266	Infinity	0.03384868
788496	taxon:9606	2.3300772	497.689707	1.73E-04	177548	1902	small nuclear ribonucleoprotein D2 polypeptide	gene	biological_process-&-1&-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005685-&&-U1 snRNP-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0003723-&&-RNA binding	G:9606:SNRPD2			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPD2	0.501877347	0.42917033	0.25268259	110	4	0.029441515	FALSE	30.58695652	SNRPD2	SNRPD2	228.6111111	32.51477593	0	109	0	0.77832047	FALSE	1	SNRPD2	481056	Infinity	0.05484689
789977	taxon:9606	2.48589885	577.6105431	2.00E-04	174206	1902	synaptopodin	gene	biological_process-&-1&-GO:0008542-&&-visual learning-%%-GO:0032233-&&-positive regulation of actin filament bundle assembly-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:1905355-&&-spine apparatus assembly-%%-GO:0098886-&&-modification of dendritic spine|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0097444-&&-spine apparatus-%%-GO:0030018-&&-Z disc-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:SYNPO			KEGG-&-1&-hsa04530-&&-Tight junction	SYNPO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNPO	0.469692533	0.40226898	0.15996664	110	4	0.00930676	FALSE	17.47058824	SYNPO	SYNPO	96.07272727	19.98044021	0	110	0	0.75235019	FALSE	0	SYNPO	350810	Infinity	0.0302277
791377	taxon:9606	2.28044746	1403.876798	3.21E-04	168895	1902	cell cycle and apoptosis regulator 2	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2000003-&&-positive regulation of DNA damage checkpoint-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0090311-&&-regulation of protein deacetylation-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0008380-&&-RNA splicing-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006397-&&-mRNA processing-%%-GO:0009411-&&-response to UV-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007049-&&-cell cycle-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0044609-&&-DBIRD complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004857-&&-enzyme inhibitor activity	G:9606:CCAR2				CCAR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCAR2	0.508883249	0.43851043	0.10431532	109	4	0.020080976	FALSE	12.19767442	CCAR2	CCAR2	191.7706422	14.046213	0	109	0	0.78659209	FALSE	0	CCAR2	700144	Infinity	0.0429072
788142	taxon:9606	2.29588782	1451.618739	3.10E-04	178165	1902	glutaminyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0007420-&&-brain development-%%-GO:0006425-&&-glutaminyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004819-&&-glutamine-tRNA ligase activity	G:9606:QARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa01100-&&-Metabolic pathways	QARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-QARS	0.505037783	0.43556135	0.13931363	109	4	0.020611102	FALSE	16.01162791	QARS	QARS	174.7247706	18.71237143	0	109	0	0.7840187	FALSE	0	QARS	581520	Infinity	0.03999975
788696	taxon:9606	2.40885458	658.0022654	3.16E-04	177167	1902	TNF receptor superfamily member 1B	gene	biological_process-&-1&-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0050779-&&-RNA destabilization-%%-GO:0006954-&&-inflammatory response-%%-GO:0007568-&&-aging-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043196-&&-varicosity|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TNFRSF1B	TNFRSF1B	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF1B	0.489173529	0.41513506	0.07670605	109	4	0.014954206	FALSE	12	TNFRSF1B	TNFRSF1B	121.5700935	13.45688291	0	108	0	0.7651909	FALSE	1	TNFRSF1B	487858	Infinity	0.033198
792969	taxon:9606	2.28659209	467.1016378	7.64E-04	181065	1902	FK506 binding protein 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0031072-&&-heat shock protein binding	G:9606:FKBP5			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	FKBP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP5	0.491722869	0.43733205	0.07526334	109	4	0.009858046	FALSE	9.574074074	FKBP5	FKBP5	125.4770642	9.98104065	0	109	0	0.78556798	FALSE	0	FKBP5	942812	Infinity	0.02827127
789571	taxon:9606	2.36048527	803.4745659	4.96E-04	175158	1902	centrosomal protein 170	gene	cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005819-&&-spindle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP170				CEP170	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP170	0.488577521	0.4236417	0.09106354	109	4	0.010605946	FALSE	11.33870968	CEP170	CEP170	130.6330275	12.40080085	0	109	0	0.77325246	FALSE	0	CEP170	740418	Infinity	0.03286038
789992	taxon:9606	2.33165275	1016.104878	1.79E-04	174179	1902	poly(U) binding splicing factor 60	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding	G:9606:PUF60			KEGG-&-1&-hsa03040-&&-Spliceosome	PUF60	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PUF60	0.505356018	0.42888033	0.15852583	109	4	0.022632727	FALSE	20.76136364	PUF60	PUF60	184.8598131	23.03698552	0	108	0	0.77805788	FALSE	1	PUF60	398704	Infinity	0.04449093
790266	taxon:9606	2.33417363	1643.230715	4.64E-04	173477	1902	KIAA0368	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043248-&&-proteasome assembly|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005813-&&-centrosome-%%-GO:0005770-&&-late endosome-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0005771-&&-multivesicular body-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032947-&&-protein complex scaffold-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:KIAA0368				KIAA0368	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA0368	0.495826893	0.42841714	0.08324839	109	4	0.014224122	FALSE	11.16455696	KIAA0368	KIAA0368	140.8990826	12.17217001	0	109	0	0.77763773	FALSE	0	KIAA0368	688908	Infinity	0.03415773
791640	taxon:9606	2.52465732	688.5441491	2.93E-04	167683	1902	centrosomal protein 76	gene	biological_process-&-1&-GO:0046599-&&-regulation of centriole replication-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP76				CEP76	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP76	0.470795421	0.39609336	0.0657667	108	4	0.015388003	FALSE	10.81818182	CEP76	CEP76	98.47222222	11.15064069	0	108	0	0.74589045	FALSE	0	CEP76	402434	Infinity	0.03331638
788551	taxon:9606	2.3499291	836.8259838	3.72E-04	177455	1902	SPT5 homolog, DSIF elongation factor subunit	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0039692-&&-single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006354-&&-DNA-templated transcription, elongation-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0032785-&&-negative regulation of DNA-templated transcription, elongation-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010033-&&-response to organic substance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0032044-&&-DSIF complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:SUPT5H				SUPT5H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT5H	0.497056089	0.42554475	0.09955076	108	4	0.014260936	FALSE	13.55882353	SUPT5H	SUPT5H	144.8962264	15.50315251	0	107	0	0.77501182	FALSE	1	SUPT5H	572294	Infinity	0.03586681
788643	taxon:9606	2.40932724	768.9643913	2.68E-04	177262	1902	SEM1, 26S proteasome complex subunit	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0043248-&&-proteasome assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0005829-&&-cytosol-%%-GO:0032039-&&-integrator complex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SEM1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome-%%-hsa03440-&&-Homologous recombination	SEM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEM1	0.49247774	0.41505362	0.15299412	108	4	0.014031125	FALSE	19.44155844	SEM1	SEM1	128.75	20.92516163	0	108	0	0.76511213	FALSE	0	SEM1	423550	Infinity	0.03515028
793285	taxon:9606	2.28659209	648.5490358	4.67E-04	180372	1902	hydroxysteroid 17-beta dehydrogenase 10	gene	biological_process-&-1&-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0070901-&&-mitochondrial tRNA methylation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0090646-&&-mitochondrial tRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0047015-&&-3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008709-&&-cholate 7-alpha-dehydrogenase activity-%%-GO:0030283-&&-testosterone dehydrogenase [NAD(P)] activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:HSD17B10			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	HSD17B10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD17B10	0.498756219	0.43733205	0.12434861	108	4	0.018099438	FALSE	17.07246377	HSD17B10	HSD17B10	176.6886793	18.71641527	0	107	0	0.78556798	FALSE	1	HSD17B10	736110	Infinity	0.03988032
789244	taxon:9606	2.37293209	383.9475601	5.31E-04	175901	1902	nuclear receptor coactivator 1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0060713-&&-labyrinthine layer morphogenesis-%%-GO:0021766-&&-hippocampus development-%%-GO:0021549-&&-cerebellum development-%%-GO:0044849-&&-estrous cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0007595-&&-lactation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0000435-&&-positive regulation of transcription from RNA polymerase II promoter by galactose-%%-GO:0045925-&&-positive regulation of female receptivity-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0032570-&&-response to progesterone-%%-GO:0002155-&&-regulation of thyroid hormone mediated signaling pathway-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0060179-&&-male mating behavior-%%-GO:0021854-&&-hypothalamus development-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0008584-&&-male gonad development-%%-GO:0032355-&&-response to estradiol-%%-GO:2001038-&&-regulation of cellular response to drug-%%-GO:1904017-&&-cellular response to Thyroglobulin triiodothyronine|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0001012-&&-RNA polymerase II regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0033142-&&-progesterone receptor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0032403-&&-protein complex binding	G:9606:NCOA1	NCOA1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	NCOA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA1	0.487982963	0.42141956	0.13548967	108	4	0.010853476	FALSE	19.19672131	NCOA1	NCOA1	123.990566	20.5416852	0	107	0	0.77117798	FALSE	1	NCOA1	722262	Infinity	0.03170632
789944	taxon:9606	2.41830786	1330.907434	4.02E-04	174289	1902	adenosylhomocysteinase like 1	gene	biological_process-&-1&-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0031440-&&-regulation of mRNA 3'-end processing-%%-GO:0038166-&&-angiotensin-activated signaling pathway-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0008150-&&-biological_process-%%-GO:0044070-&&-regulation of anion transport-%%-GO:0032412-&&-regulation of ion transmembrane transporter activity-%%-GO:0042045-&&-epithelial fluid transport-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0033353-&&-S-adenosylmethionine cycle-%%-GO:1903779-&&-regulation of cardiac conduction|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004013-&&-adenosylhomocysteinase activity	G:9606:AHCYL1			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways	AHCYL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHCYL1	0.485766202	0.41351228	0.07008086	108	4	0.008287495	FALSE	8.458333333	AHCYL1	AHCYL1	96.6509434	10.05943595	0	107	0	0.76361536	FALSE	1	AHCYL1	532976	Infinity	0.02676442
790361	taxon:9606	2.38506381	196.6739851	1.19E-04	173217	1902	ribosomal protein L13a	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0006412-&&-translation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006413-&&-translational initiation-%%-GO:1901194-&&-negative regulation of formation of translation preinitiation complex-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0097452-&&-GAIT complex-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0015934-&&-large ribosomal subunit-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL13A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL13A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL13A	0.496594427	0.41927599	0.5832468	108	4	0.039592635	FALSE	66.65346535	RPL13A	RPL13A	227.7962963	67.93214524	0	108	0	0.76915603	FALSE	0	RPL13A	234836	Infinity	0.05971907
790428	taxon:9606	2.39703797	705.3681556	4.02E-04	173019	1902	large tumor suppressor kinase 2	gene	biological_process-&-1&-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0046620-&&-regulation of organ growth-%%-GO:0001828-&&-inner cell mass cellular morphogenesis-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0034613-&&-cellular protein localization-%%-GO:0051301-&&-cell division-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0035329-&&-hippo signaling-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001827-&&-inner cell mass cell fate commitment-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:LATS2			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	LATS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LATS2	0.489322758	0.41718154	0.07834681	108	4	0.008889201	FALSE	10.45901639	LATS2	LATS2	106.5283019	11.5944792	0	107	0	0.76716034	FALSE	1	LATS2	542510	Infinity	0.02843284
790859	taxon:9606	2.45249724	501.6320256	4.48E-04	170874	1902	TERF2 interacting protein	gene	biological_process-&-1&-GO:1901985-&&-positive regulation of protein acetylation-%%-GO:0032205-&&-negative regulation of telomere maintenance-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0048239-&&-negative regulation of DNA recombination at telomere-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000723-&&-telomere maintenance-%%-GO:0016233-&&-telomere capping-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0031848-&&-protection from non-homologous end joining at telomere-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0070187-&&-shelterin complex-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0030870-&&-Mre11 complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042162-&&-telomeric DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding	G:9606:TERF2IP				TERF2IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERF2IP	0.479378362	0.40774766	0.06410256	107	4	0.012592182	FALSE	11.06557377	TERF2IP	TERF2IP	113.7428571	11.74034827	0	106	0	0.75791713	FALSE	1	TERF2IP	634494	Infinity	0.03344825
787940	taxon:9606	2.2917914	1152.343614	2.59E-04	178536	1902	proliferation-associated 2G4	gene	biological_process-&-1&-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0006417-&&-regulation of translation-%%-GO:0008283-&&-cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006364-&&-rRNA processing-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PA2G4				PA2G4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PA2G4	0.506632975	0.43633989	0.13577852	107	4	0.023959164	FALSE	16.81395349	PA2G4	PA2G4	195.5046729	17.98356007	0	107	0	0.78470143	FALSE	0	PA2G4	547690	Infinity	0.04442066
788099	taxon:9606	2.33779738	1024.141501	3.70E-04	178241	1902	solute carrier family 25 member 3	gene	biological_process-&-1&-GO:0006839-&&-mitochondrial transport-%%-GO:0035435-&&-phosphate ion transmembrane transport-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0015293-&&-symporter activity-%%-GO:0015320-&&-phosphate ion carrier activity-%%-GO:0032403-&&-protein complex binding	G:9606:SLC25A3				SLC25A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A3	0.495061728	0.42775307	0.13330982	107	4	0.017604299	FALSE	15.11428571	SLC25A3	SLC25A3	169.9439252	17.10199369	0	107	0	0.77703377	FALSE	0	SLC25A3	709972	Infinity	0.04127858
788499	taxon:9606	2.36473925	536.3890198	1.99E-04	177547	1902	small nuclear ribonucleoprotein D3 polypeptide	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008334-&&-histone mRNA metabolic process|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071010-&&-prespliceosome-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005685-&&-U1 snRNP-%%-GO:0000243-&&-commitment complex-%%-GO:0005686-&&-U2 snRNP-%%-GO:0097526-&&-spliceosomal tri-snRNP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005683-&&-U7 snRNP-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0071209-&&-U7 snRNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0030620-&&-U2 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0071208-&&-histone pre-mRNA DCP binding	G:9606:SNRPD3			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa03040-&&-Spliceosome	SNRPD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPD3	0.498911353	0.42287961	0.23152883	107	4	0.028695883	FALSE	26.01111111	SNRPD3	SNRPD3	222.5420561	27.52385602	0	107	0	0.77254346	FALSE	0	SNRPD3	513942	Infinity	0.05633503
788916	taxon:9606	2.38742713	808.9085666	5.50E-04	176601	1902	transgelin 2	gene	biological_process-&-1&-GO:0030855-&&-epithelial cell differentiation-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:TAGLN2				TAGLN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAGLN2	0.491572173	0.41886095	0.13472051	107	4	0.014136703	FALSE	15.01369863	TAGLN2	TAGLN2	146.5327103	17.33373971	0	107	0	0.76876214	FALSE	0	TAGLN2	842112	Infinity	0.03850811
793075	taxon:9606	2.25854735	997.5628505	4.16E-04	180801	1902	general transcription factor IIi	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0014886-&&-transition between slow and fast fiber-%%-GO:0051481-&&-negative regulation of cytosolic calcium ion concentration-%%-GO:0016525-&&-negative regulation of angiogenesis|cellular_component-&-1&-GO:0042995-&&-cell projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:GTF2I			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors-%%-hsa04022-&&-cGMP-PKG signaling pathway	GTF2I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2I	0.506632975	0.44276247	0.12124542	107	4	0.022573119	FALSE	17.50617284	GTF2I	GTF2I	221.2666667	18.6061096	0	106	0	0.79024211	FALSE	1	GTF2I	820202	Infinity	0.04790571
789160	taxon:9606	2.32314479	532.022171	1.28E-04	176069	1902	squamous cell carcinoma antigen recognized by T-cells 1	gene	biological_process-&-1&-GO:0007050-&&-cell cycle arrest-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000481-&&-maturation of 5S rRNA-%%-GO:0045585-&&-positive regulation of cytotoxic T cell differentiation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005829-&&-cytosol-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SART1			KEGG-&-1&-hsa03040-&&-Spliceosome	SART1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SART1	0.50471995	0.430451	0.27087912	107	4	0.02684718	FALSE	32.40217391	SART1	SART1	220.6190476	34.87694356	0	106	0	0.77947587	FALSE	1	SART1	358136	Infinity	0.052329
789728	taxon:9606	2.30455333	1398.7707	7.01E-04	174815	1902	programmed cell death 6 interacting protein	gene	biological_process-&-1&-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0090559-&&-regulation of membrane permeability-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0000915-&&-actomyosin contractile ring assembly-%%-GO:0090611-&&-ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0015031-&&-protein transport-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0019058-&&-viral life cycle-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006997-&&-nucleus organization-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903551-&&-regulation of extracellular exosome assembly-%%-GO:1903553-&&-positive regulation of extracellular exosome assembly-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0045199-&&-maintenance of epithelial cell apical/basal polarity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0001772-&&-immunological synapse-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005829-&&-cytosol-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0042641-&&-actomyosin-%%-GO:0016020-&&-membrane-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0031871-&&-proteinase activated receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PDCD6IP			KEGG-&-1&-hsa04144-&&-Endocytosis	PDCD6IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD6IP	0.499377335	0.43392357	0.07527473	107	4	0.011792502	FALSE	10.64788732	PDCD6IP	PDCD6IP	147.3428571	12.60367591	0	106	0	0.78257444	FALSE	1	PDCD6IP	949550	Infinity	0.03410622
789769	taxon:9606	2.2503545	787.5109632	3.60E-04	174729	1902	G3BP stress granule assembly factor 1	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006810-&&-transport-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:G3BP1				G3BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-G3BP1	0.506313131	0.44437443	0.13754579	107	4	0.022340883	FALSE	17.72727273	G3BP1	G3BP1	210.8666667	19.20655806	0	106	0	0.79160758	FALSE	1	G3BP1	670404	Infinity	0.04523656
790154	taxon:9606	2.46069009	705.5933984	3.61E-04	173755	1902	ninein like	gene	biological_process-&-1&-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NINL				NINL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NINL	0.47273799	0.40639006	0.07035796	107	4	0.007712347	FALSE	8.327272727	NINL	NINL	91.54205607	8.8883492	0	107	0	0.75655165	FALSE	0	NINL	481912	Infinity	0.02737982
790569	taxon:9606	2.50953206	1421.488013	3.60E-04	172108	1902	forkhead box B1	gene	biological_process-&-1&-GO:0007595-&&-lactation-%%-GO:0061381-&&-cell migration in diencephalon-%%-GO:0033504-&&-floor plate development-%%-GO:0001756-&&-somitogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0008542-&&-visual learning-%%-GO:0022029-&&-telencephalon cell migration-%%-GO:0061030-&&-epithelial cell differentiation involved in mammary gland alveolus development-%%-GO:0061379-&&-inferior colliculus development-%%-GO:0021794-&&-thalamus development-%%-GO:0021510-&&-spinal cord development-%%-GO:0001655-&&-urogenital system development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0061377-&&-mammary gland lobule development-%%-GO:0007412-&&-axon target recognition-%%-GO:0021855-&&-hypothalamus cell migration-%%-GO:0030901-&&-midbrain development-%%-GO:0061374-&&-mammillothalamic axonal tract development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0021767-&&-mammillary body development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:FOXB1				FOXB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXB1	0.472181336	0.39848066	0.03647799	106	4	0.007981997	FALSE	4.711864407	FOXB1	FOXB1	84.16037736	5.594428681	0	106	0	0.74841132	FALSE	0	FOXB1	502424	Infinity	0.02779878
791064	taxon:9606	2.49046794	633.0732876	1.87E-04	170177	1902	PIN2/TERF1 interacting, telomerase inhibitor 1	gene	biological_process-&-1&-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:1902570-&&-protein localization to nucleolus-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0051972-&&-regulation of telomerase activity-%%-GO:1904751-&&-positive regulation of protein localization to nucleolus-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:1904744-&&-positive regulation of telomeric DNA binding-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005819-&&-spindle-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0010521-&&-telomerase inhibitor activity-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PINX1				PINX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PINX1	0.468868752	0.40153097	0.1083558	106	4	0.018858109	FALSE	14.85333333	PINX1	PINX1	136.5283019	15.4137039	0	106	0	0.75158868	FALSE	0	PINX1	415614	Infinity	0.04324373
787235	taxon:9606	2.37041122	575.1326794	9.01E-04	179823	1902	insulin receptor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0008544-&&-epidermis development-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0031017-&&-exocrine pancreas development-%%-GO:0045995-&&-regulation of embryonic development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0030238-&&-male sex determination-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:2000194-&&-regulation of female gonad development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0008584-&&-male gonad development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0030325-&&-adrenal gland development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0019087-&&-transformation of host cell by virus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0051446-&&-positive regulation of meiotic cell cycle-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0060267-&&-positive regulation of respiratory burst|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005899-&&-insulin receptor complex-%%-GO:0043235-&&-receptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0051425-&&-PTB domain binding-%%-GO:0043559-&&-insulin binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005009-&&-insulin-activated receptor activity-%%-GO:0031994-&&-insulin-like growth factor I binding	G:9606:INSR	INSR	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway	INSR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INSR	0.47894894	0.42186773	0.10156833	106	4	0.007401562	FALSE	15.67857143	INSR	INSR	107.5673077	17.16231581	0	105	0	0.77159813	FALSE	1	INSR	899016	Infinity	0.02757396
787624	taxon:9606	2.35134709	622.1528034	1.16E-04	179071	1902	NOP2 nucleolar protein	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0070475-&&-rRNA base methylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000470-&&-maturation of LSU-rRNA|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0009383-&&-rRNA (cytosine-C5-)-methyltransferase activity	G:9606:NOP2				NOP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP2	0.500468019	0.42528813	0.29739443	106	4	0.029396037	FALSE	32.61111111	NOP2	NOP2	214.1509434	35.80257309	0	106	0	0.77477548	FALSE	0	NOP2	300898	Infinity	0.05299221
787742	taxon:9606	2.282023	676.9637291	1.27E-04	162465	1902	heterogeneous nuclear ribonucleoprotein A3	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:1990124-&&-messenger ribonucleoprotein complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0051033-&&-RNA transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:HNRNPA3			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA3	0.510828025	0.43820768	0.26019766	106	4	0.03188432	FALSE	29.63265306	HNRNPA3	HNRNPA3	254.3962264	31.65183873	0	106	0	0.7863295	FALSE	0	HNRNPA3	402074	Infinity	0.05701395
787808	taxon:9606	2.32015125	508.584591	6.49E-04	178757	1902	protein kinase C beta	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035408-&&-histone H3-T6 phosphorylation-%%-GO:0006816-&&-calcium ion transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0071322-&&-cellular response to carbohydrate stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0010829-&&-negative regulation of glucose transport-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042113-&&-B cell activation-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0002250-&&-adaptive immune response-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0004698-&&-calcium-dependent protein kinase C activity-%%-GO:0035403-&&-histone kinase activity (H3-T6 specific)-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0005524-&&-ATP binding	G:9606:PRKCB	PRKCB	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04970-&&-Salivary secretion	PRKCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCB	0.48902439	0.43100638	0.07617625	106	4	0.012841968	FALSE	13.13793103	PRKCB	PRKCB	142.2980769	13.75551888	0	105	0	0.77997479	FALSE	1	PRKCB	988644	Infinity	0.0337017
792288	taxon:9606	2.39751063	1135.887327	3.84E-04	182280	1902	cyclin dependent kinase 8	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007346-&&-regulation of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:CDK8				CDK8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK8	0.487389851	0.4170993	0.14115011	106	4	0.010474551	FALSE	13.77464789	CDK8	CDK8	121.4230769	16.74824328	0	105	0	0.76708156	FALSE	1	CDK8	547390	Infinity	0.03231496
788428	taxon:9606	2.30817709	419.2423093	1.42E-04	177690	1902	serine and arginine rich splicing factor 3	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:1990825-&&-sequence-specific mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRSF3			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF3	0.504085481	0.43324232	0.23539982	106	4	0.027605671	FALSE	26.97752809	SRSF3	SRSF3	219.3584906	29.12458316	0	106	0	0.78197048	FALSE	0	SRSF3	385774	Infinity	0.05103515
788465	taxon:9606	2.37403498	803.8449177	2.51E-04	177584	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007286-&&-spermatid development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0042393-&&-histone binding-%%-GO:0004386-&&-helicase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:SMARCA2			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA2	0.496594427	0.42122379	0.19101527	106	4	0.018182175	FALSE	22.08433735	SMARCA2	SMARCA2	172.2264151	24.12028389	0	106	0	0.77099417	FALSE	0	SMARCA2	539266	Infinity	0.04421489
789216	taxon:9606	2.33574917	934.8072774	4.23E-04	175977	1902	protein inhibitor of activated STAT 1	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0065004-&&-protein-DNA complex assembly-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0008542-&&-visual learning-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061665-&&-SUMO ligase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:PIAS1			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05160-&&-Hepatitis C	PIAS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS1	0.49338665	0.42812816	0.10474235	106	4	0.011380463	FALSE	14.78082192	PIAS1	PIAS1	133.7788462	16.81263519	0	105	0	0.77737514	FALSE	1	PIAS1	642844	Infinity	0.03237164
790029	taxon:9606	2.3018749	878.1688036	6.12E-04	174056	1902	nudix hydrolase 21	gene	biological_process-&-1&-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006397-&&-mRNA processing-%%-GO:0051262-&&-protein tetramerization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0031124-&&-mRNA 3'-end processing|cellular_component-&-1&-GO:0005849-&&-mRNA cleavage factor complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0042382-&&-paraspeckles-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0016787-&&-hydrolase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0017091-&&-AU-rich element binding-%%-GO:0003723-&&-RNA binding	G:9606:NUDT21			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	NUDT21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDT21	0.503294634	0.43442847	0.09970127	106	4	0.020860156	FALSE	14.29333333	NUDT21	NUDT21	197.4038462	15.33631019	0	105	0	0.78302085	FALSE	1	NUDT21	920832	Infinity	0.04549686
787825	taxon:9606	2.26910351	747.9930949	6.80E-04	178746	1902	protein kinase C zeta	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:2000553-&&-positive regulation of T-helper 2 cell cytokine production-%%-GO:2000664-&&-positive regulation of interleukin-5 secretion-%%-GO:0007616-&&-long-term memory-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051899-&&-membrane depolarization-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0031584-&&-activation of phospholipase D activity-%%-GO:0006954-&&-inflammatory response-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0016477-&&-cell migration-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation-%%-GO:1990138-&&-neuron projection extension-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:2001181-&&-positive regulation of interleukin-10 secretion-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000667-&&-positive regulation of interleukin-13 secretion-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0070528-&&-protein kinase C signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005768-&&-endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043203-&&-axon hillock-%%-GO:0045179-&&-apical cortex-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0031252-&&-cell leading edge-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005911-&&-cell-cell junction-%%-GO:0045121-&&-membrane raft-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0031941-&&-filamentous actin-%%-GO:0016020-&&-membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0030054-&&-cell junction-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0043274-&&-phospholipase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0043560-&&-insulin receptor substrate binding	G:9606:PRKCZ	PRKCZ	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa04360-&&-Axon guidance-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04611-&&-Platelet activation	PRKCZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCZ	0.495367511	0.44070268	0.09956215	105	4	0.011422966	FALSE	13.85294118	PRKCZ	PRKCZ	143.1359223	15.361492	0	104	0	0.78848275	FALSE	1	PRKCZ	868218	Infinity	0.03148399
788161	taxon:9606	2.35371041	658.0767897	5.16E-04	178146	1902	RAB5C, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0015031-&&-protein transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0048227-&&-plasma membrane to endosome transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0031901-&&-early endosome membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005769-&&-early endosome-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019003-&&-GDP binding	G:9606:RAB5C			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome-%%-hsa05146-&&-Amoebiasis-%%-hsa05152-&&-Tuberculosis	RAB5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB5C	0.49066993	0.4248611	0.10384615	105	4	0.013055132	FALSE	13.56451613	RAB5C	RAB5C	141.9142857	15.33899145	0	105	0	0.7743816	FALSE	0	RAB5C	752424	Infinity	0.03544484
788943	taxon:9606	2.24310698	1318.827986	3.27E-04	176552	1902	insulin receptor substrate 4	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0008286-&&-insulin receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:IRS4	IRS4	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	IRS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRS4	0.505037783	0.44581021	0.10565391	105	4	0.01744652	FALSE	13.55421687	IRS4	IRS4	188.038835	15.62674055	0	104	0	0.7928155	FALSE	1	IRS4	700580	Infinity	0.03992332
789024	taxon:9606	2.34725067	919.5977241	3.77E-04	176349	1902	ubiquitin specific peptidase 11	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:USP11				USP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP11	0.496748219	0.42603034	0.06510565	105	4	0.011633583	FALSE	9.46875	USP11	USP11	130.9126214	10.21765623	0	104	0	0.77545822	FALSE	1	USP11	561690	Infinity	0.03221905
793351	taxon:9606	2.30707421	734.7415665	7.11E-04	180254	1902	nuclear receptor subfamily 4 group A member 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0061469-&&-regulation of type B pancreatic cell proliferation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:0071376-&&-cellular response to corticotropin-releasing hormone stimulus-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NR4A1	NR4A1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	NR4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR4A1	0.496594427	0.43344943	0.07443366	105	4	0.01217411	FALSE	12.94117647	NR4A1	NR4A1	131.9708738	13.84194835	0	104	0	0.7821543	FALSE	1	NR4A1	786272	Infinity	0.03064729
789513	taxon:9606	2.41720498	652.7346428	4.18E-04	175296	1902	centrosomal protein 57	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0007286-&&-spermatid development-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043015-&&-gamma-tubulin binding	G:9606:CEP57				CEP57	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP57	0.484007242	0.41370095	0.06813187	105	4	0.019268006	FALSE	10.08333333	CEP57	CEP57	137.6857143	10.44050108	0	105	0	0.76379917	FALSE	0	CEP57	603652	Infinity	0.03816134
789644	taxon:9606	2.2886403	1027.620202	3.33E-04	174987	1902	tubulin alpha 1b	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0051301-&&-cell division-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0071353-&&-cellular response to interleukin-4|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005198-&&-structural molecule activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:TUBA1B			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome-%%-hsa04210-&&-Apoptosis-%%-hsa04530-&&-Tight junction	TUBA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA1B	0.507755619	0.43694066	0.10714286	105	4	0.019807225	FALSE	12.81176471	TUBA1B	TUBA1B	179.9809524	14.08963089	0	105	0	0.78522662	FALSE	0	TUBA1B	649402	Infinity	0.04068286
789976	taxon:9606	2.37135655	1120.222813	5.22E-04	174207	1902	GABA type A receptor associated protein like 2	gene	biological_process-&-1&-GO:0006914-&&-autophagy-%%-GO:0061024-&&-membrane organization-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0015031-&&-protein transport-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0050811-&&-GABA receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0000149-&&-SNARE binding	G:9606:GABARAPL2			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	GABARAPL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABARAPL2	0.482841662	0.42169955	0.06813187	105	4	0.008312483	FALSE	7.610169492	GABARAPL2	GABARAPL2	98.80952381	9.384410534	0	105	0	0.77144058	FALSE	0	GABARAPL2	634156	Infinity	0.02534389
789968	taxon:9606	2.44808571	382.2907854	1.97E-04	174217	1902	chromobox 3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048511-&&-rhythmic process-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0035985-&&-senescence-associated heterochromatin focus-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005819-&&-spindle-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:1990226-&&-histone methyltransferase binding	G:9606:CBX3				CBX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX3	0.483569491	0.40848243	0.23853036	105	4	0.022004509	FALSE	30.65333333	CBX3	CBX3	188.184466	31.9148525	0	104	0	0.75865238	FALSE	1	CBX3	467990	Infinity	0.05465712
790179	taxon:9606	2.43563888	580.4733191	3.46E-04	173704	1902	TRAF2 and NCK interacting kinase	gene	biological_process-&-1&-GO:0007256-&&-activation of JNKK activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030033-&&-microvillus assembly-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0048814-&&-regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0055037-&&-recycling endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:TNIK				TNIK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNIK	0.481103779	0.41056989	0.03160099	105	4	0.007982443	FALSE	6.388888889	TNIK	TNIK	93.66990291	6.638450713	0	104	0	0.76072685	FALSE	1	TNIK	467472	Infinity	0.02674902
791307	taxon:9606	2.42650071	357.1135268	1.94E-04	169262	1902	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	gene	biological_process-&-1&-GO:0051304-&&-chromosome separation-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0009117-&&-nucleotide metabolic process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006325-&&-chromatin organization|cellular_component-&-1&-GO:0000792-&&-heterochromatin-%%-GO:0043596-&&-nuclear replication fork-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004386-&&-helicase activity	G:9606:SMARCAD1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	SMARCAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCAD1	0.489770992	0.4121161	0.12322629	104	4	0.016665813	FALSE	15.02898551	SMARCAD1	SMARCAD1	141.0096154	15.58120595	0	104	0	0.76224988	FALSE	0	SMARCAD1	339764	Infinity	0.0394048
787214	taxon:9606	2.35780684	889.3890769	3.80E-04	179855	1902	MYC associated factor X	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048678-&&-response to axon injury-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0032868-&&-response to insulin-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0032403-&&-protein complex binding	G:9606:MAX			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	MAX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAX	0.494146642	0.42412295	0.07086003	104	4	0.012749033	FALSE	9.52238806	MAX	MAX	133.4019608	10.42637948	0	103	0	0.77369886	FALSE	1	MAX	588594	Infinity	0.0333157
787208	taxon:9606	2.24799118	849.3086774	3.82E-04	179866	1902	microtubule associated protein tau	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:1902474-&&-positive regulation of protein localization to synapse-%%-GO:0098930-&&-axonal transport-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0072386-&&-plus-end-directed organelle transport along microtubule-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0001774-&&-microglial cell activation-%%-GO:0048143-&&-astrocyte activation-%%-GO:0031113-&&-regulation of microtubule polymerization-%%-GO:1905689-&&-positive regulation of diacylglycerol kinase activity-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0031175-&&-neuron projection development-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0050808-&&-synapse organization-%%-GO:1902988-&&-neurofibrillary tangle assembly-%%-GO:0034605-&&-cellular response to heat-%%-GO:1903748-&&-negative regulation of establishment of protein localization to mitochondrion-%%-GO:0048699-&&-generation of neurons-%%-GO:0051259-&&-protein oligomerization-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:0010917-&&-negative regulation of mitochondrial membrane potential-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:0090258-&&-negative regulation of mitochondrial fission-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0007613-&&-memory-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0048312-&&-intracellular distribution of mitochondria|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0030425-&&-dendrite-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005874-&&-microtubule-%%-GO:0016020-&&-membrane-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0036477-&&-somatodendritic compartment-%%-GO:0016607-&&-nuclear speck-%%-GO:0045298-&&-tubulin complex-%%-GO:0005875-&&-microtubule associated complex-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0044297-&&-cell body-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0071813-&&-lipoprotein particle binding-%%-GO:0003779-&&-actin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0048018-&&-receptor agonist activity-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0003677-&&-DNA binding-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:MAPT			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04010-&&-MAPK signaling pathway	MAPT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPT	0.501720363	0.4448416	0.11706465	104	4	0.014382211	FALSE	15.86842105	MAPT	MAPT	171.1764706	17.75219499	0	103	0	0.79200147	FALSE	1	MAPT	657504	Infinity	0.03655845
787411	taxon:9606	2.35749173	957.5676681	4.02E-04	179479	1902	nuclear cap binding protein subunit 1	gene	biological_process-&-1&-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900363-&&-regulation of mRNA polyadenylation-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0010467-&&-gene expression-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:0051168-&&-nuclear export-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0008334-&&-histone mRNA metabolic process|cellular_component-&-1&-GO:0005846-&&-nuclear cap binding complex-%%-GO:0034518-&&-RNA cap binding complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005845-&&-mRNA cap binding complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0003723-&&-RNA binding	G:9606:NCBP1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	NCBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCBP1	0.499066584	0.42417964	0.1178118	104	4	0.019445399	FALSE	14.21052632	NCBP1	NCBP1	176.8173077	15.80254246	0	104	0	0.77375138	FALSE	0	NCBP1	615102	Infinity	0.04426496
792593	taxon:9606	2.33259808	816.4309014	3.17E-04	181750	1902	desmoplakin	gene	biological_process-&-1&-GO:0071896-&&-protein localization to adherens junction-%%-GO:0031424-&&-keratinization-%%-GO:0086073-&&-bundle of His cell-Purkinje myocyte adhesion involved in cell communication-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0002934-&&-desmosome organization-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0034332-&&-adherens junction organization-%%-GO:0042060-&&-wound healing-%%-GO:0070268-&&-cornification-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0008544-&&-epidermis development|cellular_component-&-1&-GO:0005882-&&-intermediate filament-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0001533-&&-cornified envelope-%%-GO:0014704-&&-intercalated disc-%%-GO:0030057-&&-desmosome-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016323-&&-basolateral plasma membrane|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0086083-&&-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	G:9606:DSP			KEGG-&-1&-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	DSP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSP	0.496748219	0.42870652	0.10347505	104	4	0.021538779	FALSE	14.54166667	DSP	DSP	214.8529412	15.51403969	0	103	0	0.77790032	FALSE	1	DSP	756186	Infinity	0.05183729
788567	taxon:9606	2.39057823	992.3253259	2.75E-04	177422	1902	transcriptional adaptor 2A	gene	biological_process-&-1&-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0000125-&&-PCAF complex|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:TADA2A				TADA2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TADA2A	0.494756323	0.41830884	0.106236	104	4	0.014214124	FALSE	12.36486486	TADA2A	TADA2A	129.8846154	14.05329021	0	104	0	0.76823696	FALSE	0	TADA2A	460630	Infinity	0.03409825
788715	taxon:9606	2.24972428	756.7644719	5.37E-04	177134	1902	tropomyosin 3	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0007015-&&-actin filament organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005862-&&-muscle thin filament tropomyosin-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding	G:9606:TPM3			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM3	0.504402516	0.44449891	0.10483401	104	4	0.015606179	FALSE	14.30882353	TPM3	TPM3	180.5196078	15.80954481	0	103	0	0.79171262	FALSE	1	TPM3	812888	Infinity	0.03863442
788759	taxon:9606	2.36647235	1096.962839	7.44E-04	176998	1902	zinc finger and BTB domain containing 16	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0001823-&&-mesonephros development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0051216-&&-cartilage development-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0030097-&&-hemopoiesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007417-&&-central nervous system development-%%-GO:0035136-&&-forelimb morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048133-&&-male germ-line stem cell asymmetric division-%%-GO:0051138-&&-positive regulation of NK T cell differentiation|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0001206-&&-transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:ZBTB16			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	ZBTB16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB16	0.49247774	0.42256991	0.09240924	104	4	0.011634395	FALSE	14.15942029	ZBTB16	ZBTB16	136.1764706	16.00606421	0	103	0	0.77225461	FALSE	1	ZBTB16	886140	Infinity	0.03454016
788806	taxon:9606	2.238853	1236.841668	4.72E-04	176836	1902	thioredoxin	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0030091-&&-protein repair-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0006662-&&-glycerol ether metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0009314-&&-response to radiation-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033158-&&-regulation of protein import into nucleus, translocation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0047134-&&-protein-disulfide reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004791-&&-thioredoxin-disulfide reductase activity-%%-GO:0016671-&&-oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor-%%-GO:0003723-&&-RNA binding-%%-GO:0015037-&&-peptide disulfide oxidoreductase activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity	G:9606:TXN			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway	TXN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXN	0.506632975	0.44665728	0.10679612	104	4	0.01721302	FALSE	12.75	TXN	TXN	186.0576923	14.87125914	0	104	0	0.7935245	FALSE	0	TXN	825650	Infinity	0.0392838
789660	taxon:9606	2.32944698	856.5744418	4.65E-04	174954	1902	Yes associated protein 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0003143-&&-embryonic heart tube morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0048339-&&-paraxial mesoderm development-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0048368-&&-lateral mesoderm development-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1902459-&&-positive regulation of stem cell population maintenance-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0060242-&&-contact inhibition-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0030903-&&-notochord development-%%-GO:0072307-&&-regulation of metanephric nephron tubule epithelial cell differentiation-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0010837-&&-regulation of keratinocyte proliferation-%%-GO:0035329-&&-hippo signaling-%%-GO:0046622-&&-positive regulation of organ growth|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070064-&&-proline-rich region binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0003682-&&-chromatin binding	G:9606:YAP1	YAP1	TRUE	KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	YAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YAP1	0.497827436	0.42928644	0.08644511	104	4	0.010975683	FALSE	10.8358209	YAP1	YAP1	132.2403846	11.83295952	0	104	0	0.7784255	FALSE	0	YAP1	658556	Infinity	0.03167272
789810	taxon:9606	2.44052308	591.4890596	2.42E-04	174605	1902	Sin3A associated protein 18	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0061574-&&-ASAP complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003723-&&-RNA binding	G:9606:SAP18			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	SAP18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAP18	0.484592145	0.40974822	0.13946975	104	4	0.01581228	FALSE	17.31168831	SAP18	SAP18	129.7884615	19.11131368	0	104	0	0.75991282	FALSE	0	SAP18	377638	Infinity	0.03728448
787891	taxon:9606	2.3631637	760.8575954	1.73E-04	178649	1902	proteasome 26S subunit, ATPase 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0001824-&&-blastocyst development-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005634-&&-nucleus-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0016234-&&-inclusion body-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC4			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC4	0.503294634	0.42316154	0.2832667	103	4	0.016857864	FALSE	30.83908046	PSMC4	PSMC4	166.8349515	35.40906919	0	103	0	0.77280605	FALSE	0	PSMC4	392956	Infinity	0.04208508
788051	taxon:9606	2.35449819	491.1168719	2.50E-04	161922	1902	casein kinase 2 alpha 3	gene		G:9606:CSNK2A3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa04520-&&-Adherens junction-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2A3	0.496748219	0.42471895	0.07728917	103	4	0.016081059	FALSE	9.928571429	CSNK2A3	CSNK2A3	140.3883495	10.46061921	0	103	0	0.7742503	FALSE	0	CSNK2A3	476648	Infinity	0.03500619
792285	taxon:9606	2.24657318	494.7256612	7.76E-04	182284	1902	cyclin dependent kinase 5	gene	biological_process-&-1&-GO:0016079-&&-synaptic vesicle exocytosis-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0051301-&&-cell division-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0022038-&&-corpus callosum development-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0071156-&&-regulation of cell cycle arrest-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0030182-&&-neuron differentiation-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0001764-&&-neuron migration-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0043113-&&-receptor clustering-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031914-&&-negative regulation of synaptic plasticity-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0033136-&&-serine phosphorylation of STAT3 protein-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0048511-&&-rhythmic process-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0070509-&&-calcium ion import-%%-GO:0008283-&&-cell proliferation-%%-GO:0008542-&&-visual learning-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0016310-&&-phosphorylation-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1903421-&&-regulation of synaptic vesicle recycling-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0035418-&&-protein localization to synapse-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0001963-&&-synaptic transmission, dopaminergic-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0021766-&&-hippocampus development-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007416-&&-synapse assembly-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0014044-&&-Schwann cell development-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0031175-&&-neuron projection development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0021697-&&-cerebellar cortex formation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0009611-&&-response to wounding-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0048675-&&-axon extension|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0030175-&&-filopodium-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030027-&&-lamellipodium-%%-GO:0016020-&&-membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0043204-&&-perikaryon-%%-GO:0016533-&&-cyclin-dependent protein kinase 5 holoenzyme complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0030426-&&-growth cone-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0050321-&&-tau-protein kinase activity-%%-GO:0005176-&&-ErbB-2 class receptor binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0030549-&&-acetylcholine receptor activator activity-%%-GO:0016301-&&-kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:CDK5	CDK5	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05010-&&-Alzheimer disease-%%-hsa05030-&&-Cocaine addiction	CDK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK5	0.49751861	0.44512238	0.07742574	103	4	0.010516264	FALSE	11.34482759	CDK5	CDK5	142.6831683	11.9012402	0	102	0	0.7922378	FALSE	1	CDK5	914600	Infinity	0.0303906
792420	taxon:9606	2.35449819	491.1168719	2.50E-04	182049	1902	casein kinase 2 alpha 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006915-&&-apoptotic process-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0071174-&&-mitotic spindle checkpoint-%%-GO:0048511-&&-rhythmic process-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016581-&&-NuRD complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity	G:9606:CSNK2A1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04520-&&-Adherens junction-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2A1	0.496748219	0.42471895	0.07728917	103	4	0.016081059	FALSE	9.928571429	CSNK2A1	CSNK2A1	140.3883495	10.46061921	0	103	0	0.7742503	FALSE	0	CSNK2A1	476648	Infinity	0.03500619
788468	taxon:9606	2.28375611	912.2596949	3.22E-04	177581	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0090240-&&-positive regulation of histone H4 acetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:1902661-&&-positive regulation of glucose mediated signaling pathway-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:0006281-&&-DNA repair-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0039692-&&-single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0015074-&&-DNA integration-%%-GO:1900110-&&-negative regulation of histone H3-K9 dimethylation-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0007399-&&-nervous system development-%%-GO:2000618-&&-regulation of histone H4-K16 acetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0071564-&&-npBAF complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0002039-&&-p53 binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:SMARCB1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCB1	0.500468019	0.43787513	0.14019802	103	4	0.014109521	FALSE	16.08219178	SMARCB1	SMARCB1	161.5643564	17.47907087	0	102	0	0.78604065	FALSE	1	SMARCB1	608796	Infinity	0.03618608
788681	taxon:9606	2.3102253	657.7412163	5.44E-04	177204	1902	talin 1	gene	biological_process-&-1&-GO:0070527-&&-platelet aggregation-%%-GO:0016032-&&-viral process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006936-&&-muscle contraction-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0030274-&&-LIM domain binding-%%-GO:0005178-&&-integrin binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:TLN1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation	TLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLN1	0.497210167	0.43285821	0.11783743	103	4	0.017693346	FALSE	15.79104478	TLN1	TLN1	175.2621359	16.64373492	0	103	0	0.78162912	FALSE	0	TLN1	786640	Infinity	0.04093549
792808	taxon:9606	2.28990074	803.4094012	1.92E-04	181338	1902	ELAV like RNA binding protein 1	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0060965-&&-negative regulation of gene silencing by miRNA|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:1990904-&&-ribonucleoprotein complex|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0017091-&&-AU-rich element binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0019901-&&-protein kinase binding	G:9606:ELAVL1			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway	ELAVL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELAVL1	0.508077289	0.43670015	0.16415842	103	4	0.026224731	FALSE	20.48275862	ELAVL1	ELAVL1	235.9405941	22.1184431	0	102	0	0.78501654	FALSE	1	ELAVL1	477088	Infinity	0.05336591
792817	taxon:9606	2.2952576	860.1155942	3.49E-04	181317	1902	cortactin	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0097062-&&-dendritic spine maintenance-%%-GO:0048870-&&-cell motility-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0097581-&&-lamellipodium organization-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0030041-&&-actin filament polymerization-%%-GO:1903146-&&-regulation of mitophagy|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0005884-&&-actin filament-%%-GO:0005938-&&-cell cortex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0001726-&&-ruffle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone-%%-GO:0002102-&&-podosome-%%-GO:1990023-&&-mitotic spindle midzone-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005522-&&-profilin binding-%%-GO:0045296-&&-cadherin binding	G:9606:CTTN			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis	CTTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTTN	0.499844188	0.43568094	0.10970297	103	4	0.014924943	FALSE	13.91549296	CTTN	CTTN	169.3366337	15.57541071	0	102	0	0.78412373	FALSE	1	CTTN	634590	Infinity	0.03861273
788859	taxon:9606	2.35323775	779.8706217	3.31E-04	176741	1902	voltage dependent anion channel 2	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0032272-&&-negative regulation of protein polymerization-%%-GO:0006820-&&-anion transport-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:1903959-&&-regulation of anion transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex|molecular_function-&-1&-GO:0008308-&&-voltage-gated anion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0015288-&&-porin activity-%%-GO:0000166-&&-nucleotide binding	G:9606:VDAC2			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa04217-&&-Necroptosis-%%-hsa04216-&&-Ferroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	VDAC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDAC2	0.490970309	0.42494644	0.14315629	103	4	0.012913707	FALSE	14.27692308	VDAC2	VDAC2	141.8932039	16.28190983	0	103	0	0.77446037	FALSE	0	VDAC2	588532	Infinity	0.03533197
792964	taxon:9606	2.29620293	578.0327048	7.95E-04	181079	1902	four and a half LIM domains 2	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0055014-&&-atrial cardiac muscle cell development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:FHL2			KEGG-&-1&-hsa04380-&&-Osteoclast differentiation	FHL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FHL2	0.494451295	0.43550158	0.06752475	103	4	0.009252399	FALSE	12.19230769	FHL2	FHL2	127.6237624	13.0164582	0	102	0	0.78396618	FALSE	1	FHL2	877818	Infinity	0.02917507
793046	taxon:9606	2.27083662	927.9262707	9.25E-04	180840	1902	protein disulfide isomerase family A member 3	gene	biological_process-&-1&-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006621-&&-protein retention in ER lumen-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007165-&&-signal transduction-%%-GO:0006508-&&-proteolysis-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0034975-&&-protein folding in endoplasmic reticulum|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0009986-&&-cell surface-%%-GO:0045335-&&-phagocytic vesicle|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0015036-&&-disulfide oxidoreductase activity-%%-GO:0004629-&&-phospholipase C activity	G:9606:PDIA3			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	PDIA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIA3	0.501877347	0.44036634	0.09765848	103	4	0.014768358	FALSE	12.02985075	PDIA3	PDIA3	160.9805825	13.1531145	0	103	0	0.7881939	FALSE	0	PDIA3	1082686	Infinity	0.03553368
789175	taxon:9606	2.38979045	468.3610647	2.40E-04	176045	1902	histone cluster 2 H2A family member c	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2AC			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST2H2AC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2AC	0.493994456	0.41844673	0.27489054	103	4	0.021622051	FALSE	31.4025974	HIST2H2AC	HIST2H2AC	189.815534	33.04711028	0	103	0	0.76836826	FALSE	0	HIST2H2AC	505918	Infinity	0.0499489
789208	taxon:9606	2.47644556	491.1683152	2.12E-04	175996	1902	chromobox 4	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032183-&&-SUMO binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0035064-&&-methylated histone binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0016874-&&-ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0051219-&&-phosphoprotein binding	G:9606:CBX4				CBX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX4	0.480239521	0.40380456	0.18237624	103	4	0.019080466	FALSE	23.23376623	CBX4	CBX4	172.2178218	24.59705876	0	102	0	0.75392574	FALSE	1	CBX4	464428	Infinity	0.05285493
789932	taxon:9606	2.3001418	778.9382234	5.17E-04	174321	1902	prostaglandin E synthase 3	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:1905323-&&-telomerase holoenzyme complex assembly-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0007165-&&-signal transduction-%%-GO:0000723-&&-telomere maintenance-%%-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003720-&&-telomerase activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0050220-&&-prostaglandin-E synthase activity	G:9606:PTGES3			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	PTGES3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGES3	0.495673671	0.43475581	0.08138614	103	4	0.013272393	FALSE	11.6969697	PTGES3	PTGES3	143.6732673	12.53786047	0	102	0	0.7833097	FALSE	1	PTGES3	742924	Infinity	0.03296089
789934	taxon:9606	2.41169056	540.5122694	5.46E-04	174322	1902	nuclear distribution C, dynein complex regulator	gene	biological_process-&-1&-GO:0008283-&&-cell proliferation-%%-GO:0006457-&&-protein folding-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:NUDC				NUDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDC	0.487982963	0.41464689	0.04644965	103	4	0.010598783	FALSE	6.592592593	NUDC	NUDC	116.368932	6.92702606	0	103	0	0.76471824	FALSE	0	NUDC	712850	Infinity	0.03194514
790492	taxon:9606	2.29068851	884.594221	2.42E-04	172707	1902	SUMO1/sentrin/SMT3 specific peptidase 3	gene	biological_process-&-1&-GO:0016926-&&-protein desumoylation-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0016929-&&-SUMO-specific protease activity	G:9606:SENP3				SENP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SENP3	0.503768844	0.43654997	0.10508281	103	4	0.018165546	FALSE	12.45205479	SENP3	SENP3	171.6893204	13.45184635	0	103	0	0.78488525	FALSE	0	SENP3	485678	Infinity	0.03885912
790611	taxon:9606	2.43059713	265.0343099	4.83E-04	171761	1902	fizzy and cell division cycle 20 related 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0090344-&&-negative regulation of cell aging-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006281-&&-DNA repair-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0010997-&&-anaphase-promoting complex binding	G:9606:FZR1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	FZR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FZR1	0.476247031	0.41142153	0.08192584	102	4	0.007914478	FALSE	9.860465116	FZR1	FZR1	99.21568627	10.11785714	0	102	0	0.76156714	FALSE	0	FZR1	589214	Infinity	0.02808383
790707	taxon:9606	2.40932724	461.8703142	1.64E-04	171418	1902	transformer 2 alpha homolog	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:TRA2A			KEGG-&-1&-hsa03040-&&-Spliceosome	TRA2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRA2A	0.490970309	0.41505362	0.17744127	102	4	0.017281396	FALSE	19.88235294	TRA2A	TRA2A	158.3039216	21.05847571	0	102	0	0.76511213	FALSE	0	TRA2A	326560	Infinity	0.04294469
787266	taxon:9606	2.28895541	703.1865442	3.89E-04	179776	1902	junction plakoglobin	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0086073-&&-bundle of His cell-Purkinje myocyte adhesion involved in cell communication-%%-GO:0071603-&&-endothelial cell-cell adhesion-%%-GO:0034333-&&-adherens junction assembly-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0002159-&&-desmosome assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0050982-&&-detection of mechanical stimulus-%%-GO:0031424-&&-keratinization-%%-GO:0016477-&&-cell migration-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0034332-&&-adherens junction organization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0030056-&&-hemidesmosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0030057-&&-desmosome-%%-GO:0030018-&&-Z disc-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005911-&&-cell-cell junction-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005915-&&-zonula adherens-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005882-&&-intermediate filament-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0071665-&&-gamma-catenin-TCF7L2 complex-%%-GO:0001533-&&-cornified envelope-%%-GO:0005856-&&-cytoskeleton-%%-GO:0014704-&&-intercalated disc-%%-GO:0016342-&&-catenin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0086083-&&-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005199-&&-structural constituent of cell wall-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:JUP			KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05226-&&-Gastric cancer	JUP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JUP	0.502034429	0.43688051	0.1125995	102	4	0.016241344	FALSE	13.41538462	JUP	JUP	175.5294118	14.17499652	0	102	0	0.7851741	FALSE	0	JUP	696236	Infinity	0.03966998
787416	taxon:9606	2.48826217	262.737842	6.57E-04	179469	1902	NDUFA4, mitochondrial complex associated	gene	biological_process-&-1&-GO:0006123-&&-mitochondrial electron transport, cytochrome c to oxygen-%%-GO:1902600-&&-hydrogen ion transmembrane transport-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005751-&&-mitochondrial respiratory chain complex IV-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding-%%-GO:0004129-&&-cytochrome-c oxidase activity	G:9606:NDUFA4			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA4	0.456980057	0.40188691	0.08727273	102	4	0.005731426	FALSE	8.861111111	NDUFA4	NDUFA4	86.09	9.1549485	0	101	0	0.7519563	FALSE	1	NDUFA4	801576	Infinity	0.02706549
788066	taxon:9606	2.44099575	454.6387662	7.75E-05	178288	1902	ribosomal protein L26	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL26			KEGG-&-1&-hsa03010-&&-Ribosome	RPL26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL26	0.491271057	0.40966888	0.40264026	102	4	0.03378066	FALSE	43.03125	RPL26	RPL26	216.6568628	44.65485695	0	102	0	0.75983404	FALSE	0	RPL26	256914	Infinity	0.06211212
788191	taxon:9606	2.30486844	901.7712744	5.23E-04	178106	1902	RAS p21 protein activator 1	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0001570-&&-vasculogenesis-%%-GO:0051252-&&-regulation of RNA metabolic process-%%-GO:0009790-&&-embryo development-%%-GO:0007165-&&-signal transduction-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031235-&&-intrinsic component of the cytoplasmic side of the plasma membrane-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0019870-&&-potassium channel inhibitor activity	G:9606:RASA1	RASA1	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	RASA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASA1	0.491271057	0.43386424	0.10868687	102	4	0.009103802	FALSE	15.13846154	RASA1	RASA1	134.69	17.68817576	0	101	0	0.78252193	FALSE	1	RASA1	711854	Infinity	0.03121289
792396	taxon:9606	2.35969749	639.591491	7.12E-04	182098	1902	CRK like proto-oncogene, adaptor protein	gene	biological_process-&-1&-GO:0048538-&&-thymus development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007507-&&-heart development-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0060017-&&-parathyroid gland development-%%-GO:0001568-&&-blood vessel development-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007254-&&-JNK cascade-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:CRKL			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton	CRKL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRKL	0.488875343	0.42378313	0.1125995	102	4	0.009469752	FALSE	13.88135593	CRKL	CRKL	124.9019608	15.43765613	0	102	0	0.77338375	FALSE	0	CRKL	894366	Infinity	0.03142042
788403	taxon:9606	2.34977155	657.8093757	8.12E-04	177732	1902	serine/threonine kinase 11	gene	biological_process-&-1&-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0001944-&&-vasculature development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0030154-&&-cell differentiation-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0051055-&&-negative regulation of lipid biosynthetic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:1904262-&&-negative regulation of TORC1 signaling-%%-GO:0006914-&&-autophagy-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007409-&&-axonogenesis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0007399-&&-nervous system development-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0036399-&&-TCR signalosome assembly-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043276-&&-anoikis-%%-GO:0051645-&&-Golgi localization-%%-GO:0097484-&&-dendrite extension-%%-GO:0045059-&&-positive thymic T cell selection|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0036398-&&-TCR signalosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0002039-&&-p53 binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0030275-&&-LRR domain binding	G:9606:STK11	STK11	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	STK11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK11	0.480239521	0.42557329	0.04707071	102	4	0.008302877	FALSE	9	STK11	STK11	108.26	9.687848183	0	101	0	0.77503808	FALSE	1	STK11	808674	Infinity	0.02682878
792841	taxon:9606	2.27288483	687.723404	2.37E-04	181277	1902	glutamyl-prolyl-tRNA synthetase	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006433-&&-prolyl-tRNA aminoacylation-%%-GO:0006424-&&-glutamyl-tRNA aminoacylation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006418-&&-tRNA aminoacylation for protein translation|cellular_component-&-1&-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0097452-&&-GAIT complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004818-&&-glutamate-tRNA ligase activity-%%-GO:0004827-&&-proline-tRNA ligase activity-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:EPRS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism	EPRS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPRS	0.505674653	0.4399695	0.15996894	102	4	0.022200992	FALSE	17.325	EPRS	EPRS	213.8921569	19.37359312	0	102	0	0.78785253	FALSE	0	EPRS	516390	Infinity	0.04726682
790585	taxon:9606	2.33244052	624.8250865	4.89E-04	172068	1902	calcyclin binding protein	gene	biological_process-&-1&-GO:0060548-&&-negative regulation of cell death-%%-GO:0007568-&&-aging-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0060416-&&-response to growth hormone-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0071277-&&-cellular response to calcium ion|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0044297-&&-cell body-%%-GO:0030877-&&-beta-catenin destruction complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CACYBP			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	CACYBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACYBP	0.495520544	0.42873548	0.05833849	101	4	0.010754093	FALSE	9.206896552	CACYBP	CACYBP	131.040404	9.764258216	0	100	0	0.77792658	FALSE	1	CACYBP	689630	Infinity	0.03153071
788437	taxon:9606	2.32708366	696.9564194	1.47E-04	144907	1902	RBM14-RBM4 readthrough	gene		G:9606:RBM14-RBM4				RBM14-RBM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM14-RBM4	0.503927113	0.42972241	0.18693069	101	4	0.025040938	FALSE	21.03488372	RBM14-RBM4	RBM14-RBM4	222.4653465	22.46883562	0	101	0	0.77881939	FALSE	0	RBM14-RBM4	411050	Infinity	0.05310467
788474	taxon:9606	2.33448873	825.90478	5.22E-04	177578	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007399-&&-nervous system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0006337-&&-nucleosome disassembly|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:SMARCD1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCD1	0.495367511	0.42835932	0.1419802	101	4	0.014843486	FALSE	15.94117647	SMARCD1	SMARCD1	162.4059406	16.78222797	0	101	0	0.77758521	FALSE	0	SMARCD1	775268	Infinity	0.03909603
788594	taxon:9606	2.45832677	483.2095059	0.00103499	177373	1902	elongin C	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070449-&&-elongin complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:ELOC			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	ELOC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELOC	0.475823198	0.40678075	0.06217822	101	4	0.009702377	FALSE	7.66	ELOC	ELOC	106.9108911	8.140115953	0	101	0	0.75694554	FALSE	0	ELOC	1801474	Infinity	0.03169786
793195	taxon:9606	2.41137545	342.2486876	7.14E-04	180545	1902	HRas proto-oncogene, GTPase	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0050900-&&-leukocyte migration-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0090398-&&-cellular senescence-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0008283-&&-cell proliferation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0035900-&&-response to isolation stress-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:1900029-&&-positive regulation of ruffle assembly-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0007411-&&-axon guidance-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0007165-&&-signal transduction-%%-GO:0006935-&&-chemotaxis-%%-GO:0006897-&&-endocytosis-%%-GO:2000630-&&-positive regulation of miRNA metabolic process-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005525-&&-GTP binding	G:9606:HRAS			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05219-&&-Bladder cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04144-&&-Endocytosis-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	HRAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HRAS	0.467502186	0.41470108	0.04555762	101	4	0.005590271	FALSE	7.547619048	HRAS	HRAS	90.2020202	7.829796497	0	100	0	0.76477076	FALSE	1	HRAS	759660	Infinity	0.0247896
789255	taxon:9606	2.3812825	835.1637113	2.04E-04	175891	1902	eukaryotic translation initiation factor 3 subunit A	gene	biological_process-&-1&-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0002188-&&-translation reinitiation-%%-GO:0001732-&&-formation of cytoplasmic translation initiation complex|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0005874-&&-microtubule-%%-GO:0043614-&&-multi-eIF complex-%%-GO:0071540-&&-eukaryotic translation initiation factor 3 complex, eIF3e-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0003723-&&-RNA binding	G:9606:EIF3A			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3A	0.492780338	0.41994178	0.16039604	101	4	0.02033259	FALSE	17.93421053	EIF3A	EIF3A	168.3267327	19.87195737	0	101	0	0.76978625	FALSE	0	EIF3A	400208	Infinity	0.04381079
789667	taxon:9606	2.32708366	696.9564194	1.47E-04	174939	1902	RNA binding motif protein 14	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0016575-&&-histone deacetylation-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0046600-&&-negative regulation of centriole replication-%%-GO:0006260-&&-DNA replication-%%-GO:0009725-&&-response to hormone-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0006310-&&-DNA recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0098534-&&-centriole assembly|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:RBM14				RBM14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM14	0.503927113	0.42972241	0.18693069	101	4	0.025040938	FALSE	21.03488372	RBM14	RBM14	222.4653465	22.46883562	0	101	0	0.77881939	FALSE	0	RBM14	411050	Infinity	0.05310467
789695	taxon:9606	2.45942965	671.3976867	5.13E-04	174878	1902	nuclear receptor coactivator 2	gene	biological_process-&-1&-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1904017-&&-cellular response to Thyroglobulin triiodothyronine-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0045475-&&-locomotor rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0032922-&&-circadian regulation of gene expression|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0001162-&&-RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding	G:9606:NCOA2	NCOA2	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	NCOA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA2	0.471764706	0.40659833	0.10183467	101	4	0.012488252	FALSE	14.01587302	NCOA2	NCOA2	130.3333333	14.8364613	0	100	0	0.75676172	FALSE	1	NCOA2	791704	Infinity	0.03850264
790756	taxon:9606	2.43233023	485.7184632	1.98E-04	154932	1902	histone cluster 2 H3 family member d	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H3D			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST2H3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H3D	0.488428745	0.41112838	0.05434343	100	4	0.013307925	FALSE	6.507692308	HIST2H3D	HIST2H3D	132.27	6.857913206	0	100	0	0.76127829	FALSE	0	HIST2H3D	542198	Infinity	0.03751986
787069	taxon:9606	2.39609264	796.7644734	3.82E-04	180122	1902	immunoglobulin binding protein 1	gene	biological_process-&-1&-GO:0060632-&&-regulation of microtubule-based movement-%%-GO:0007165-&&-signal transduction-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042113-&&-B cell activation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0034612-&&-response to tumor necrosis factor|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:IGBP1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04136-&&-Autophagy - other	IGBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGBP1	0.48313253	0.41734613	0.05474747	100	4	0.009458434	FALSE	5.838709677	IGBP1	IGBP1	109.04	6.323827285	0	100	0	0.76731789	FALSE	0	IGBP1	542868	Infinity	0.0290253
787305	taxon:9606	2.39498976	699.6277112	5.12E-04	179688	1902	kinesin family member 11	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0051301-&&-cell division-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007059-&&-chromosome segregation-%%-GO:0007051-&&-spindle organization-%%-GO:0007100-&&-mitotic centrosome separation-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0046602-&&-regulation of mitotic centrosome separation-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005871-&&-kinesin complex-%%-GO:0016020-&&-membrane-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed	G:9606:KIF11				KIF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF11	0.491271057	0.41753832	0.08226383	100	4	0.016574126	FALSE	12.84615385	KIF11	KIF11	155.877551	13.38912483	0	99	0	0.76750171	FALSE	1	KIF11	800944	Infinity	0.04135267
791901	taxon:9606	2.46226564	1503.513408	5.64E-04	182910	1902	amino-terminal enhancer of split	gene	biological_process-&-1&-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001501-&&-skeletal system development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0060761-&&-negative regulation of response to cytokine stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0040008-&&-regulation of growth|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:AES				AES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AES	0.46627907	0.40613002	0.06648433	100	4	0.005665094	FALSE	8.620689655	AES	AES	88.40816327	11.75228713	0	99	0	0.75628906	FALSE	1	AES	673362	Infinity	0.02642439
787838	taxon:9606	2.348196	525.0836646	6.13E-04	178735	1902	mitogen-activated protein kinase 9	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0061833-&&-protein localization to tricellular tight junction-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0007254-&&-JNK cascade-%%-GO:0007258-&&-JUN phosphorylation-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0048666-&&-neuron development-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0009612-&&-response to mechanical stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004705-&&-JUN kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:MAPK9			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK9	0.477807566	0.42585883	0.06921944	100	4	0.007645208	FALSE	9.755102041	MAPK9	MAPK9	113.5612245	10.21315952	0	99	0	0.77530067	FALSE	1	MAPK9	757952	Infinity	0.02802657
791926	taxon:9606	2.33858516	1226.841844	4.44E-04	166481	1902	Fas binding factor 1	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0043297-&&-apical junction assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0090162-&&-establishment of epithelial cell polarity|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0043296-&&-apical junction complex-%%-GO:0045095-&&-keratin filament-%%-GO:0097539-&&-ciliary transition fiber|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FBF1				FBF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBF1	0.492931776	0.42760897	0.06525253	100	4	0.009356956	FALSE	7.047619048	FBF1	FBF1	122.45	8.018383611	0	100	0	0.77690247	FALSE	0	FBF1	645660	Infinity	0.02977864
791978	taxon:9606	2.40097684	708.5549984	3.84E-04	182777	1902	baculoviral IAP repeat containing 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0039535-&&-regulation of RIG-I signaling pathway-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0001890-&&-placenta development-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:1902523-&&-positive regulation of protein K63-linked ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000116-&&-regulation of cysteine-type endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070424-&&-regulation of nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:1902527-&&-positive regulation of protein monoubiquitination-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1902443-&&-negative regulation of ripoptosome assembly involved in necroptotic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0070266-&&-necroptotic process-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0051591-&&-response to cAMP-%%-GO:1902524-&&-positive regulation of protein K48-linked ubiquitination|cellular_component-&-1&-GO:0001741-&&-XY body-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0045121-&&-membrane raft-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016740-&&-transferase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0098770-&&-FBXO family protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:BIRC2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	BIRC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC2	0.482696359	0.41649715	0.11824111	100	4	0.009288281	FALSE	15.29850746	BIRC2	BIRC2	117.4081633	17.32451185	0	99	0	0.76650386	FALSE	1	BIRC2	522748	Infinity	0.03148539
788402	taxon:9606	2.43233023	485.7184632	1.98E-04	161348	1902	histone cluster 2 H3 family member a	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H3A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST2H3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H3A	0.488428745	0.41112838	0.05434343	100	4	0.013307925	FALSE	6.507692308	HIST2H3A	HIST2H3A	132.27	6.857913206	0	100	0	0.76127829	FALSE	0	HIST2H3A	542198	Infinity	0.03751986
792624	taxon:9606	2.49613991	675.3167016	3.45E-04	165318	1902	neural precursor cell expressed, developmentally down-regulated 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000242-&&-pericentriolar material-%%-GO:0000922-&&-spindle pole-%%-GO:0005814-&&-centriole-%%-GO:0036064-&&-ciliary basal body-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NEDD1				NEDD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD1	0.473855244	0.40061857	0.09010101	100	4	0.012891514	FALSE	11.80645161	NEDD1	NEDD1	112.19	12.79196137	0	100	0	0.75064335	FALSE	0	NEDD1	532882	Infinity	0.03584586
792754	taxon:9606	2.43233023	485.7184632	1.98E-04	165048	1902	histone cluster 2 H3 family member c	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H3C			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST2H3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H3C	0.488428745	0.41112838	0.05434343	100	4	0.013307925	FALSE	6.507692308	HIST2H3C	HIST2H3C	132.27	6.857913206	0	100	0	0.76127829	FALSE	0	HIST2H3C	542198	Infinity	0.03751986
792823	taxon:9606	2.39546242	669.340427	4.33E-04	181301	1902	endothelial PAS domain protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0007165-&&-signal transduction-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0001525-&&-angiogenesis-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0007601-&&-visual perception-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0048625-&&-myoblast fate commitment-%%-GO:0001666-&&-response to hypoxia-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0030324-&&-lung development-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0043129-&&-surfactant homeostasis-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0042415-&&-norepinephrine metabolic process-%%-GO:0048469-&&-cell maturation|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035035-&&-histone acetyltransferase binding	G:9606:EPAS1			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma	EPAS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPAS1	0.48902439	0.41745593	0.08836524	100	4	0.009697702	FALSE	10.80701754	EPAS1	EPAS1	120.2142857	11.67939448	0	99	0	0.76742293	FALSE	1	EPAS1	616880	Infinity	0.03194097
792974	taxon:9606	2.62060816	209.6034104	2.22E-04	181057	1902	forkhead box L1	gene	biological_process-&-1&-GO:0007275-&&-multicellular organism development-%%-GO:0030166-&&-proteoglycan biosynthetic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0061146-&&-Peyer's patch morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0007495-&&-visceral mesoderm-endoderm interaction involved in midgut development-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXL1				FOXL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXL1	0.429106474	0.38159081	0.01616162	100	4	0.004713966	FALSE	2.117647059	FOXL1	FOXL1	58.44	2.188552189	0	100	0	0.72989864	FALSE	0	FOXL1	283448	Infinity	0.02488213
793208	taxon:9606	2.3930991	639.3756868	5.99E-04	180524	1902	heat shock transcription factor 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009299-&&-mRNA transcription-%%-GO:0051028-&&-mRNA transport-%%-GO:0034605-&&-cellular response to heat-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:2001033-&&-negative regulation of double-strand break repair via nonhomologous end joining-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1904385-&&-cellular response to angiotensin-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:0072738-&&-cellular response to diamide-%%-GO:0006281-&&-DNA repair-%%-GO:1904843-&&-cellular response to nitroglycerin-%%-GO:1990910-&&-response to hypobaric hypoxia-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0007143-&&-female meiotic division-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0033574-&&-response to testosterone-%%-GO:0034620-&&-cellular response to unfolded protein-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0061408-&&-positive regulation of transcription from RNA polymerase II promoter in response to heat stress-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035865-&&-cellular response to potassium ion-%%-GO:1902512-&&-positive regulation of apoptotic DNA fragmentation-%%-GO:0006952-&&-defense response-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:1900365-&&-positive regulation of mRNA polyadenylation-%%-GO:1904845-&&-cellular response to L-glutamine-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090261-&&-positive regulation of inclusion body assembly-%%-GO:0006397-&&-mRNA processing-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0014823-&&-response to activity-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1990911-&&-response to psychosocial stress-%%-GO:1904528-&&-positive regulation of microtubule binding-%%-GO:0060136-&&-embryonic process involved in female pregnancy-%%-GO:0007584-&&-response to nutrient|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0045120-&&-pronucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000792-&&-heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097165-&&-nuclear stress granule-%%-GO:0097431-&&-mitotic spindle pole-%%-GO:0000791-&&-euchromatin-%%-GO:0016605-&&-PML body-%%-GO:1990904-&&-ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0097677-&&-STAT family protein binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0043621-&&-protein self-association-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0098847-&&-sequence-specific single stranded DNA binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0001162-&&-RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0061770-&&-translation elongation factor binding	G:9606:HSF1	HSF1	TRUE	KEGG-&-1&-hsa05134-&&-Legionellosis	HSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSF1	0.474837182	0.41786819	0.06985062	100	4	0.009724564	FALSE	9.533333333	HSF1	HSF1	120.6020408	10.19664296	0	99	0	0.76781682	FALSE	1	HSF1	725870	Infinity	0.03186921
791154	taxon:9606	2.46510162	555.102783	1.60E-04	169875	1902	Ly1 antibody reactive	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:LYAR				LYAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYAR	0.48211602	0.40566279	0.16821274	99	4	0.019687852	FALSE	18.73972603	LYAR	LYAR	151.6161616	19.71794583	0	99	0	0.7558164	FALSE	0	LYAR	293462	Infinity	0.04535783
791381	taxon:9606	2.41421144	528.0868164	8.29E-04	168861	1902	SRP receptor beta subunit	gene	biological_process-&-1&-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005785-&&-signal recognition particle receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0005047-&&-signal recognition particle binding-%%-GO:0005525-&&-GTP binding	G:9606:SRPRB			KEGG-&-1&-hsa03060-&&-Protein export	SRPRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPRB	0.471764706	0.41421393	0.0430839	99	4	0.008162653	FALSE	4.727272727	SRPRB	SRPRB	111.2121212	4.884686857	0	99	0	0.76429809	FALSE	0	SRPRB	965320	Infinity	0.03052509
787307	taxon:9606	2.30770443	720.130656	3.11E-04	179684	1902	karyopherin subunit alpha 1	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0019054-&&-modulation by virus of host process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:KPNA1			KEGG-&-1&-hsa05164-&&-Influenza A	KPNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA1	0.502821317	0.43333106	0.11193568	99	4	0.017482191	FALSE	13.70833333	KPNA1	KPNA1	176.5454546	14.79228387	0	99	0	0.78204926	FALSE	0	KPNA1	562152	Infinity	0.04088125
791625	taxon:9606	2.65920908	151.5347205	4.12E-04	167753	1902	tectonic family member 2	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0060170-&&-ciliary membrane-%%-GO:0036038-&&-MKS complex	G:9606:TCTN2				TCTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCTN2	0.408246373	0.37605166	0.03153989	99	4	0.003045759	FALSE	4.75	TCTN2	TCTN2	51.09090909	4.925925926	0	99	0	0.72346515	FALSE	0	TCTN2	486664	Infinity	0.02419913
788288	taxon:9606	2.35843706	300.8581263	4.73E-05	177951	1902	ribosomal protein S17	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS17			KEGG-&-1&-hsa03010-&&-Ribosome	RPS17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS17	0.50140669	0.42400962	0.48526077	99	4	0.03709114	FALSE	48.90625	RPS17	RPS17	255.7171717	49.98140624	0	99	0	0.77359382	FALSE	0	RPS17	216370	Infinity	0.06391331
792406	taxon:9606	2.25760202	819.0290663	3.81E-04	182069	1902	chromosome segregation 1 like	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005049-&&-nuclear export signal receptor activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:CSE1L				CSE1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSE1L	0.505037783	0.44294787	0.12739641	99	4	0.019175401	FALSE	13.88	CSE1L	CSE1L	207.5555556	15.35940739	0	99	0	0.79039966	FALSE	0	CSE1L	683500	Infinity	0.04487469
792689	taxon:9606	2.40617615	262.1135981	4.60E-04	181556	1902	growth arrest and DNA damage inducible alpha	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006281-&&-DNA repair-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007098-&&-centrosome cycle-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding	G:9606:GADD45A			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GADD45A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GADD45A	0.481537076	0.41559717	0.06378866	99	4	0.013945938	FALSE	10.83636364	GADD45A	GADD45A	138.5670103	11.09244122	0	98	0	0.76563731	FALSE	1	GADD45A	686176	Infinity	0.0375213
788707	taxon:9606	2.33039231	1818.570952	3.58E-04	177144	1902	tumor protein p53 binding protein 2	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007049-&&-cell cycle-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0002039-&&-p53 binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0051059-&&-NF-kappaB binding	G:9606:TP53BP2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway	TP53BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53BP2	0.497827436	0.4291123	0.0992268	99	4	0.010626053	FALSE	11.71428571	TP53BP2	TP53BP2	144.3298969	14.55518208	0	98	0	0.77826795	FALSE	1	TP53BP2	610052	Infinity	0.03453695
788929	taxon:9606	2.45170947	894.0397431	3.52E-04	176577	1902	NCK adaptor protein 2	gene	biological_process-&-1&-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0007165-&&-signal transduction-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0042110-&&-T cell activation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0007176-&&-regulation of epidermal growth factor-activated receptor activity-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0036493-&&-positive regulation of translation in response to endoplasmic reticulum stress-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007172-&&-signal complex assembly-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0060996-&&-dendritic spine development-%%-GO:0007015-&&-actin filament organization-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0097110-&&-scaffold protein binding	G:9606:NCK2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NCK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCK2	0.467502186	0.40787867	0.05906357	99	4	0.005335307	FALSE	7.773584906	NCK2	NCK2	88.91752577	8.699125708	0	98	0	0.75804842	FALSE	1	NCK2	454336	Infinity	0.02607285
789643	taxon:9606	2.30266268	487.998104	5.42E-04	174984	1902	tubulin beta 3 class III	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0030424-&&-axon-%%-GO:0030425-&&-dendrite-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0042277-&&-peptide binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB3			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB3	0.499221911	0.43427985	0.08864152	99	4	0.014900411	FALSE	11.64615385	TUBB3	TUBB3	169.010101	12.24307698	0	99	0	0.78288955	FALSE	0	TUBB3	868396	Infinity	0.03893743
790023	taxon:9606	2.41878053	675.0066838	2.08E-04	174069	1902	receptor interacting serine/threonine kinase 3	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0002819-&&-regulation of adaptive immune response-%%-GO:0048535-&&-lymph node development-%%-GO:0060545-&&-positive regulation of necroptotic process-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0090312-&&-positive regulation of protein deacetylation-%%-GO:0048538-&&-thymus development-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0001914-&&-regulation of T cell mediated cytotoxicity-%%-GO:0048536-&&-spleen development-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0070266-&&-necroptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0051351-&&-positive regulation of ligase activity-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051353-&&-positive regulation of oxidoreductase activity-%%-GO:0010922-&&-positive regulation of phosphatase activity-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0046006-&&-regulation of activated T cell proliferation-%%-GO:2000452-&&-regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation-%%-GO:0032649-&&-regulation of interferon-gamma production-%%-GO:0070235-&&-regulation of activation-induced cell death of T cells|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0097342-&&-ripoptosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005524-&&-ATP binding	G:9606:RIPK3			KEGG-&-1&-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	RIPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK3	0.487982963	0.41343147	0.08784364	99	4	0.014391288	FALSE	11.25316456	RIPK3	RIPK3	131.1443299	12.54261395	0	98	0	0.76353658	FALSE	1	RIPK3	357182	Infinity	0.03623919
790077	taxon:9606	2.34599023	600.1135382	6.76E-04	173928	1902	checkpoint kinase 2	gene	biological_process-&-1&-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:1903926-&&-cellular response to bisphenol A-%%-GO:0001302-&&-replicative cell aging-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0072428-&&-signal transduction involved in intra-S DNA damage checkpoint-%%-GO:1903416-&&-response to glycoside-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0090399-&&-replicative senescence-%%-GO:2000002-&&-negative regulation of DNA damage checkpoint-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CHEK2	CHEK2	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence	CHEK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHEK2	0.490220049	0.42625923	0.06572165	99	4	0.010360925	FALSE	10.94642857	CHEK2	CHEK2	122.3814433	11.54566788	0	98	0	0.77566829	FALSE	1	CHEK2	764898	Infinity	0.03016946
790481	taxon:9606	2.27146683	730.0953974	1.14E-04	172729	1902	SERPINE1 mRNA binding protein 1	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:SERBP1				SERBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERBP1	0.506313131	0.44024416	0.20640034	99	4	0.028563857	FALSE	23.54545455	SERBP1	SERBP1	252.8762887	24.5350879	0	98	0	0.78808886	FALSE	1	SERBP1	398672	Infinity	0.05552839
790498	taxon:9606	2.25003939	1002.466191	2.24E-04	172687	1902	phosphoglycerate dehydrogenase	gene	biological_process-&-1&-GO:0006566-&&-threonine metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006564-&&-L-serine biosynthetic process-%%-GO:0007420-&&-brain development-%%-GO:0009448-&&-gamma-aminobutyric acid metabolic process-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0031175-&&-neuron projection development-%%-GO:0021510-&&-spinal cord development-%%-GO:0021915-&&-neural tube development-%%-GO:0006544-&&-glycine metabolic process-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0021782-&&-glial cell development-%%-GO:0070314-&&-G1 to G0 transition|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0004617-&&-phosphoglycerate dehydrogenase activity-%%-GO:0051287-&&-NAD binding	G:9606:PHGDH	PHGDH	TRUE	KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	PHGDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHGDH	0.506153361	0.44443666	0.14759843	99	4	0.02338485	FALSE	16.24705882	PHGDH	PHGDH	234.979798	17.86180983	0	99	0	0.7916601	FALSE	0	PHGDH	548982	Infinity	0.0503061
787227	taxon:9606	2.42461005	563.7925239	1.14E-04	179834	1902	minichromosome maintenance complex component 4	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:MCM4			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM4	0.491873658	0.41243746	0.24671053	98	4	0.022994718	FALSE	26.51898734	MCM4	MCM4	206.71875	28.16958304	0	97	0	0.76256499	FALSE	1	MCM4	324324	Infinity	0.05746687
791321	taxon:9606	2.35103198	723.5187327	1.87E-04	169179	1902	DEAD-box helicase 24	gene	biological_process-&-1&-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0016070-&&-RNA metabolic process|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003724-&&-RNA helicase activity	G:9606:DDX24				DDX24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX24	0.497210167	0.42534513	0.19100877	98	4	0.019578684	FALSE	20.67567568	DDX24	DDX24	178.3541667	22.27813394	0	97	0	0.774828	FALSE	1	DDX24	381384	Infinity	0.04392703
787358	taxon:9606	2.41421144	423.7846428	5.60E-04	179598	1902	melatonin receptor 1A	gene	biological_process-&-1&-GO:0007617-&&-mating behavior-%%-GO:0007623-&&-circadian rhythm-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0030828-&&-positive regulation of cGMP biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008502-&&-melatonin receptor activity-%%-GO:0042562-&&-hormone binding-%%-GO:0005515-&&-protein binding-%%-GO:0097159-&&-organic cyclic compound binding	G:9606:MTNR1A	MTNR1A	TRUE	KEGG-&-1&-hsa04713-&&-Circadian entrainment-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	MTNR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTNR1A	0.484885127	0.41421393	0.05460526	98	4	0.010574445	FALSE	9.745098039	MTNR1A	MTNR1A	113.1145833	10.57758361	0	97	0	0.76429809	FALSE	1	MTNR1A	637272	Infinity	0.03117527
788179	taxon:9606	2.34520246	866.698756	3.77E-04	178122	1902	Ran GTPase activating protein 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:1904117-&&-cellular response to vasopressin-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0016925-&&-protein sumoylation-%%-GO:0048678-&&-response to axon injury|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0072686-&&-mitotic spindle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005737-&&-cytoplasm-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:1990723-&&-cytoplasmic periphery of the nuclear pore complex-%%-GO:0016235-&&-aggresome-%%-GO:0044614-&&-nuclear pore cytoplasmic filaments|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0045296-&&-cadherin binding	G:9606:RANGAP1			KEGG-&-1&-hsa03013-&&-RNA transport	RANGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANGAP1	0.495826893	0.42640242	0.10197368	98	4	0.012364596	FALSE	12.47457627	RANGAP1	RANGAP1	153.3125	13.59019993	0	97	0	0.77579959	FALSE	1	RANGAP1	603734	Infinity	0.03754032
792484	taxon:9606	2.48132976	462.6742035	7.02E-04	181944	1902	BCL2 like 1	gene	biological_process-&-1&-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007281-&&-germ cell development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0008283-&&-cell proliferation-%%-GO:0040007-&&-growth-%%-GO:0007283-&&-spermatogenesis-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0009566-&&-fertilization-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0000910-&&-cytokinesis-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060154-&&-cellular process regulating host cell cycle in response to virus-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090005-&&-negative regulation of establishment of protein localization to plasma membrane-%%-GO:0071839-&&-apoptotic process in bone marrow-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0034097-&&-response to cytokine-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0019050-&&-suppression by virus of host apoptotic process-%%-GO:0046898-&&-response to cycloheximide-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1900118-&&-negative regulation of execution phase of apoptosis-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0008584-&&-male gonad development-%%-GO:0006897-&&-endocytosis-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0030054-&&-cell junction-%%-GO:0097136-&&-Bcl-2 family protein complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0051434-&&-BH3 domain binding	G:9606:BCL2L1	BCL2L1	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma	BCL2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L1	0.46078713	0.40300971	0.05679825	98	4	0.004881703	FALSE	7.85	BCL2L1	BCL2L1	76.64583333	8.195126195	0	97	0	0.75311171	FALSE	1	BCL2L1	711038	Infinity	0.02378963
788426	taxon:9606	2.33433118	725.4631852	1.79E-04	177688	1902	serine and arginine rich splicing factor 5	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0009611-&&-response to wounding-%%-GO:0097421-&&-liver regeneration-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0050733-&&-RS domain binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SRSF5			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF5	0.502821317	0.42838823	0.20892068	98	4	0.021621056	FALSE	22.41176471	SRSF5	SRSF5	193.8571429	24.42423033	0	98	0	0.77761147	FALSE	0	SRSF5	365584	Infinity	0.04668515
792605	taxon:9606	2.33354341	1411.18503	5.45E-04	181729	1902	dishevelled segment polarity protein 2	gene	biological_process-&-1&-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0034613-&&-cellular protein localization-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0051259-&&-protein oligomerization-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0001843-&&-neural tube closure-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0022007-&&-convergent extension involved in neural plate elongation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035567-&&-non-canonical Wnt signaling pathway-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0044340-&&-canonical Wnt signaling pathway involved in regulation of cell proliferation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0007379-&&-segment specification|cellular_component-&-1&-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016235-&&-aggresome-%%-GO:0005634-&&-nucleus-%%-GO:0045177-&&-apical part of cell-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005109-&&-frizzled binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:DVL2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DVL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DVL2	0.49844624	0.42853285	0.06776316	98	4	0.009704232	FALSE	9.119402985	DVL2	DVL2	131.4375	10.77946628	0	97	0	0.77774277	FALSE	1	DVL2	697024	Infinity	0.03166426
788659	taxon:9606	2.28722231	709.5076129	6.49E-04	177237	1902	transglutaminase 2	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0018153-&&-isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0060662-&&-salivary gland cavitation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis|cellular_component-&-1&-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003810-&&-protein-glutamine gamma-glutamyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding	G:9606:TGM2			KEGG-&-1&-hsa05016-&&-Huntington disease	TGM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGM2	0.498136646	0.43721155	0.08640351	98	4	0.012723548	FALSE	11.84126984	TGM2	TGM2	154.7395833	12.74423238	0	97	0	0.78546295	FALSE	1	TGM2	804708	Infinity	0.03493159
789076	taxon:9606	2.63210966	344.8377253	6.66E-04	159859	1902	keratin associated protein 10-3	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament	G:9606:KRTAP10-3				KRTAP10-3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-3	0.41749089	0.37992338	0.09780702	98	4	0.002738887	FALSE	9.515151515	KRTAP10-3	KRTAP10-3	51.6875	11.00056242	0	97	0	0.72798172	FALSE	1	KRTAP10-3	1052680	Infinity	0.02267614
789570	taxon:9606	2.3878998	744.1768667	1.92E-04	175156	1902	proteasome 26S subunit, non-ATPase 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0006508-&&-proteolysis-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity	G:9606:PSMD6			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD6	0.494908979	0.41877804	0.27687776	98	4	0.013004377	FALSE	29.69230769	PSMD6	PSMD6	143.4897959	33.00585644	0	98	0	0.76868337	FALSE	0	PSMD6	347494	Infinity	0.0375923
789761	taxon:9606	2.25602647	981.5017836	3.04E-04	174745	1902	leucine rich pentatricopeptide repeat containing	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0000961-&&-negative regulation of mitochondrial RNA catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0070129-&&-regulation of mitochondrial translation-%%-GO:0009451-&&-RNA modification-%%-GO:0047497-&&-mitochondrion transport along microtubule|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005874-&&-microtubule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:LRPPRC				LRPPRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRPPRC	0.503927113	0.44325721	0.07390351	98	4	0.019468406	FALSE	10.09210526	LRPPRC	LRPPRC	219.7083333	11.09292804	0	97	0	0.79066226	FALSE	1	LRPPRC	719850	Infinity	0.04743746
789792	taxon:9606	2.38600914	518.5867115	2.27E-04	174670	1902	proteasome 26S subunit, non-ATPase 14	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061133-&&-endopeptidase activator activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity	G:9606:PSMD14			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD14	0.49247774	0.41910988	0.29013255	98	4	0.011007909	FALSE	31.71621622	PSMD14	PSMD14	133.8979592	34.25739331	0	98	0	0.76899848	FALSE	0	PSMD14	400318	Infinity	0.03510161
790045	taxon:9606	2.31794549	645.3435541	2.65E-04	174015	1902	heterogeneous nuclear ribonucleoprotein U like 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0006396-&&-RNA processing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPUL1			KEGG-&-1&-hsa05164-&&-Influenza A	HNRNPUL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPUL1	0.500468019	0.43141653	0.16666667	98	4	0.02164207	FALSE	20.58441558	HNRNPUL1	HNRNPUL1	210.1979167	21.76092864	0	97	0	0.78034242	FALSE	1	HNRNPUL1	523668	Infinity	0.04934648
790203	taxon:9606	2.26863085	732.6036629	2.82E-04	173648	1902	TGF-beta activated kinase 1/MAP3K7 binding protein 2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TAB2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway	TAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAB2	0.50471995	0.4407945	0.14868421	98	4	0.016896168	FALSE	17.59210526	TAB2	TAB2	181.46875	19.12297004	0	97	0	0.78856153	FALSE	1	TAB2	545796	Infinity	0.03986572
790475	taxon:9606	2.39404443	2378.152467	2.41E-04	172737	1902	pre-mRNA processing factor 31	gene	biological_process-&-1&-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048254-&&-snoRNA localization-%%-GO:0071166-&&-ribonucleoprotein complex localization|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0071011-&&-precatalytic spliceosome-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0005690-&&-U4atac snRNP-%%-GO:0005687-&&-U4 snRNP|molecular_function-&-1&-GO:0070990-&&-snRNP binding-%%-GO:0030621-&&-U4 snRNA binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0030622-&&-U4atac snRNA binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF31			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF31	0.496902107	0.41770319	0.14166667	98	4	0.018274497	FALSE	16.97560976	PRPF31	PRPF31	177.9270833	20.41938361	0	97	0	0.76765926	FALSE	1	PRPF31	613960	Infinity	0.04700572
790556	taxon:9606	2.3997164	464.0904563	9.59E-05	139396	1902	U2 small nuclear RNA auxiliary factor 1 like 5	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0089701-&&-U2AF-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:U2AF1L5			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa05131-&&-Shigellosis	U2AF1L5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2AF1L5	0.495520544	0.41671591	0.26181271	97	4	0.024226712	FALSE	27.23255814	U2AF1L5	U2AF1L5	193.4123711	29.25947659	0	97	0	0.76671393	FALSE	0	U2AF1L5	264732	Infinity	0.05164274
787018	taxon:9606	2.37419253	750.5064489	7.69E-04	180223	1902	integrin subunit beta 1	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016477-&&-cell migration-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0048675-&&-axon extension-%%-GO:0030183-&&-B cell differentiation-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0001708-&&-cell fate specification-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0021943-&&-formation of radial glial scaffolds-%%-GO:0007161-&&-calcium-independent cell-matrix adhesion-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0008542-&&-visual learning-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0031623-&&-receptor internalization-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0008354-&&-germ cell migration-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0050900-&&-leukocyte migration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0010710-&&-regulation of collagen catabolic process-%%-GO:0033631-&&-cell-cell adhesion mediated by integrin-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0045214-&&-sarcomere organization-%%-GO:0050776-&&-regulation of immune response-%%-GO:0006968-&&-cellular defense response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0043197-&&-dendritic spine-%%-GO:0032154-&&-cleavage furrow-%%-GO:0034678-&&-integrin alpha8-beta1 complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0032587-&&-ruffle membrane-%%-GO:0034665-&&-integrin alpha1-beta1 complex-%%-GO:0042383-&&-sarcolemma-%%-GO:0043235-&&-receptor complex-%%-GO:0097060-&&-synaptic membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0030175-&&-filopodium-%%-GO:0034680-&&-integrin alpha10-beta1 complex-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0034681-&&-integrin alpha11-beta1 complex-%%-GO:0034677-&&-integrin alpha7-beta1 complex-%%-GO:0034666-&&-integrin alpha2-beta1 complex-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0008305-&&-integrin complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0009986-&&-cell surface-%%-GO:0055037-&&-recycling endosome-%%-GO:0016020-&&-membrane-%%-GO:0034667-&&-integrin alpha3-beta1 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042470-&&-melanosome-%%-GO:0071438-&&-invadopodium membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001968-&&-fibronectin binding-%%-GO:0005178-&&-integrin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0043236-&&-laminin binding-%%-GO:0019960-&&-C-X3-C chemokine binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003779-&&-actin binding-%%-GO:0098639-&&-collagen binding involved in cell-matrix adhesion-%%-GO:0015026-&&-coreceptor activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:ITGB1			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04145-&&-Phagosome-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa05133-&&-Pertussis-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB1	0.483278096	0.42119583	0.07950728	97	4	0.01084627	FALSE	10.78571429	ITGB1	ITGB1	134.1684211	11.55009764	0	96	0	0.77096791	FALSE	1	ITGB1	941526	Infinity	0.03454812
787333	taxon:9606	2.48148732	414.9172026	4.60E-04	179652	1902	keratin 31	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:KRT31			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT31	0.465467208	0.40298413	0.02813574	97	4	0.00480768	FALSE	3.514285714	KRT31	KRT31	77.01030928	3.655462185	0	97	0	0.75308545	FALSE	0	KRT31	539804	Infinity	0.02400985
787793	taxon:9606	2.30738932	1019.794365	5.17E-04	178773	1902	protein kinase AMP-activated catalytic subunit alpha 1	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0031000-&&-response to caffeine-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0009631-&&-cold acclimation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0061762-&&-CAMKK-AMPK signaling cascade-%%-GO:1901563-&&-response to camptothecin-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0071417-&&-cellular response to organonitrogen compound-%%-GO:2001274-&&-negative regulation of glucose import in response to insulin stimulus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0048511-&&-rhythmic process-%%-GO:0060627-&&-regulation of vesicle-mediated transport-%%-GO:0033135-&&-regulation of peptidyl-serine phosphorylation-%%-GO:0045542-&&-positive regulation of cholesterol biosynthetic process-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0009411-&&-response to UV-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0046318-&&-negative regulation of glucosylceramide biosynthetic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0014823-&&-response to activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0070301-&&-cellular response to hydrogen peroxide|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0050321-&&-tau-protein kinase activity-%%-GO:0047322-&&-[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0050405-&&-[acetyl-CoA carboxylase] kinase activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity	G:9606:PRKAA1	PRKAA1	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	PRKAA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAA1	0.497364341	0.43339024	0.07109107	97	4	0.010465965	FALSE	8.2	PRKAA1	PRKAA1	136.8762887	9.325699848	0	97	0	0.78210178	FALSE	0	PRKAA1	688742	Infinity	0.0316944
792147	taxon:9606	2.32251457	623.5166111	3.03E-04	182522	1902	actin like 6A	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0007165-&&-signal transduction-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0003407-&&-neural retina development-%%-GO:0006310-&&-DNA recombination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0021510-&&-spinal cord development-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0040008-&&-regulation of growth-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071564-&&-npBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0031011-&&-Ino80 complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ACTL6A			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	ACTL6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTL6A	0.501093408	0.4305678	0.16043814	97	4	0.01772064	FALSE	16.60869565	ACTL6A	ACTL6A	193.2474227	17.56029847	0	97	0	0.7795809	FALSE	0	ACTL6A	587082	Infinity	0.0457401
788811	taxon:9606	2.3997164	464.0904563	9.59E-05	176825	1902	U2 small nuclear RNA auxiliary factor 1	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0015030-&&-Cajal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0089701-&&-U2AF|molecular_function-&-1&-GO:0050733-&&-RS domain binding-%%-GO:0030628-&&-pre-mRNA 3'-splice site binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:U2AF1			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa05131-&&-Shigellosis	U2AF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2AF1	0.495520544	0.41671591	0.26181271	97	4	0.024226749	FALSE	27.23255814	U2AF1	U2AF1	193.4123711	29.25947659	0	97	0	0.76671393	FALSE	0	U2AF1	264732	Infinity	0.05164274
793242	taxon:9606	2.25271782	1051.234117	2.29E-04	180466	1902	isoleucyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006428-&&-isoleucyl-tRNA aminoacylation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0004822-&&-isoleucine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:IARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	IARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IARS	0.505993691	0.44390824	0.15141753	97	4	0.019990245	FALSE	14.7625	IARS	IARS	208.371134	17.0819803	0	97	0	0.7912137	FALSE	0	IARS	555108	Infinity	0.04473403
789159	taxon:9606	2.62218371	266.224326	4.50E-04	159691	1902	notch 2 N-terminal like	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NOTCH2NL				NOTCH2NL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH2NL	0.410650282	0.38136153	0.05347938	97	4	0.002185121	FALSE	4.533333333	NOTCH2NL	NOTCH2NL	51.46391753	5.093465965	0	97	0	0.72963605	FALSE	0	NOTCH2NL	945162	Infinity	0.02212181
789549	taxon:9606	2.62218371	266.224326	4.50E-04	142439	1902	notch homolog 2 N-terminal-like protein	gene		G:9606:LOC100996717				LOC100996717	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC100996717	0.410650282	0.38136153	0.05347938	97	4	0.002185121	FALSE	4.533333333	LOC100996717	LOC100996717	51.46391753	5.093465965	0	97	0	0.72963605	FALSE	0	LOC100996717	945162	Infinity	0.02212181
789557	taxon:9606	2.62218371	266.224326	4.50E-04	142420	1902	notch homolog 2 N-terminal-like protein	gene		G:9606:LOC100996763				LOC100996763	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC100996763	0.410650282	0.38136153	0.05347938	97	4	0.002185121	FALSE	4.533333333	LOC100996763	LOC100996763	51.46391753	5.093465965	0	97	0	0.72963605	FALSE	0	LOC100996763	945162	Infinity	0.02212181
789674	taxon:9606	2.28013235	707.6409509	5.62E-04	174922	1902	TGF-beta activated kinase 1 (MAP3K7) binding protein 1	gene	biological_process-&-1&-GO:0003279-&&-cardiac septum development-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0035904-&&-aorta development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0030324-&&-lung development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0019209-&&-kinase activator activity	G:9606:TAB1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05161-&&-Hepatitis B	TAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAB1	0.497981993	0.43857103	0.10839866	97	4	0.013591399	FALSE	14.81818182	TAB1	TAB1	158.8421053	15.95864273	0	96	0	0.78664461	FALSE	1	TAB1	715936	Infinity	0.0354274
789738	taxon:9606	2.24499764	959.1081699	6.47E-04	174789	1902	RAN binding protein 9	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006461-&&-protein complex assembly-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:RANBP9				RANBP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP9	0.503294634	0.44543477	0.07995521	97	4	0.013228296	FALSE	10.88235294	RANBP9	RANBP9	167.6421053	11.88452403	0	96	0	0.79250039	FALSE	1	RANBP9	863104	Infinity	0.03568011
789781	taxon:9606	2.27430282	533.3322949	1.64E-04	174692	1902	Aly/REF export factor	gene	biological_process-&-1&-GO:0031297-&&-replication fork processing-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000346-&&-transcription export complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:ALYREF			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	ALYREF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALYREF	0.505356018	0.43969519	0.21724524	97	4	0.027185267	FALSE	24.77777778	ALYREF	ALYREF	256.4421053	26.31022641	0	96	0	0.7876162	FALSE	1	ALYREF	466594	Infinity	0.05665744
789846	taxon:9606	2.33244052	975.7755745	1.96E-04	174521	1902	splicing factor 3a subunit 3	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:SF3A3			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3A3	0.501563477	0.42873548	0.20468213	97	4	0.022173077	FALSE	21.5	SF3A3	SF3A3	207.0103093	23.23303619	0	97	0	0.77792658	FALSE	0	SF3A3	440068	Infinity	0.04974766
790265	taxon:9606	2.39814085	841.7371673	4.60E-04	173482	1902	nicastrin	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0016485-&&-protein processing-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0034205-&&-beta-amyloid formation-%%-GO:0042098-&&-T cell proliferation-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0042982-&&-amyloid precursor protein metabolic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0070765-&&-gamma-secretase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004175-&&-endopeptidase activity	G:9606:NCSTN			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease	NCSTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCSTN	0.482551143	0.41698969	0.09750859	97	4	0.012484956	FALSE	10.6119403	NCSTN	NCSTN	119.4329897	11.63272353	0	97	0	0.76697652	FALSE	0	NCSTN	691294	Infinity	0.03186604
787848	taxon:9606	2.2886403	846.6594502	3.96E-04	178726	1902	eukaryotic translation initiation factor 2 alpha kinase 2	gene	biological_process-&-1&-GO:0032722-&&-positive regulation of chemokine production-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0010998-&&-regulation of translational initiation by eIF2 alpha phosphorylation-%%-GO:0009615-&&-response to virus-%%-GO:0009636-&&-response to toxic substance-%%-GO:1900225-&&-regulation of NLRP3 inflammasome complex assembly-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:1902033-&&-regulation of hematopoietic stem cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0051607-&&-defense response to virus-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:1901532-&&-regulation of hematopoietic progenitor cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006412-&&-translation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030683-&&-evasion or tolerance by virus of host immune response-%%-GO:0035455-&&-response to interferon-alpha-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:1902036-&&-regulation of hematopoietic stem cell differentiation-%%-GO:0001819-&&-positive regulation of cytokine production|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004694-&&-eukaryotic translation initiation factor 2alpha kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005524-&&-ATP binding	G:9606:EIF2AK2	EIF2AK2	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa05165-&&-Human papillomavirus infection	EIF2AK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2AK2	0.498911353	0.43694066	0.10546786	96	4	0.014788956	FALSE	13.42424242	EIF2AK2	EIF2AK2	166.1595745	14.47263238	0	95	0	0.78522662	FALSE	1	EIF2AK2	591454	Infinity	0.03745467
787976	taxon:9606	2.31038286	781.558649	4.39E-04	178479	1902	protein-L-isoaspartate (D-aspartate) O-methyltransferase	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0030091-&&-protein repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004719-&&-protein-L-isoaspartate (D-aspartate) O-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PCMT1				PCMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCMT1	0.497981993	0.4328287	0.0837337	96	4	0.017211251	FALSE	11.07575758	PCMT1	PCMT1	200.393617	12.10765906	0	95	0	0.78160286	FALSE	1	PCMT1	797382	Infinity	0.0466994
792070	taxon:9606	2.48684418	386.2653899	4.58E-04	182660	1902	CDC like kinase 1	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008283-&&-cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity	G:9606:CLK1	CLK1	TRUE	KEGG-&-1&-hsa05134-&&-Legionellosis	CLK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLK1	0.473435655	0.40211607	0.05399222	96	4	0.009579445	FALSE	9.869565217	CLK1	CLK1	94.94680851	10.22279701	0	95	0	0.75219264	FALSE	1	CLK1	532822	Infinity	0.02972711
788650	taxon:9606	2.46021743	176.2408325	0.00268137	177249	1902	transforming growth factor beta 1	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0060312-&&-regulation of blood vessel remodeling-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0060751-&&-branch elongation involved in mammary gland duct branching-%%-GO:0061035-&&-regulation of cartilage development-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0060364-&&-frontal suture morphogenesis-%%-GO:0085029-&&-extracellular matrix assembly-%%-GO:0010936-&&-negative regulation of macrophage cytokine production-%%-GO:0021915-&&-neural tube development-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007565-&&-female pregnancy-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0009749-&&-response to glucose-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:1901203-&&-positive regulation of extracellular matrix assembly-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:1905313-&&-transforming growth factor beta receptor signaling pathway involved in heart development-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0048298-&&-positive regulation of isotype switching to IgA isotypes-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0060965-&&-negative regulation of gene silencing by miRNA-%%-GO:0003179-&&-heart valve morphogenesis-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0006954-&&-inflammatory response-%%-GO:0002460-&&-adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0046732-&&-active induction of host immune response by virus-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051280-&&-negative regulation of release of sequestered calcium ion into cytosol-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043932-&&-ossification involved in bone remodeling-%%-GO:0070723-&&-response to cholesterol-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0042306-&&-regulation of protein import into nucleus-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007435-&&-salivary gland morphogenesis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0032943-&&-mononuclear cell proliferation-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:1900126-&&-negative regulation of hyaluronan biosynthetic process-%%-GO:0033280-&&-response to vitamin D-%%-GO:0043117-&&-positive regulation of vascular permeability-%%-GO:0007507-&&-heart development-%%-GO:0048468-&&-cell development-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001657-&&-ureteric bud development-%%-GO:0007406-&&-negative regulation of neuroblast proliferation-%%-GO:0007568-&&-aging-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0045066-&&-regulatory T cell differentiation-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0032740-&&-positive regulation of interleukin-17 production-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032570-&&-response to progesterone-%%-GO:0002513-&&-tolerance induction to self antigen-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0008354-&&-germ cell migration-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042552-&&-myelination-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007492-&&-endoderm development-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0048535-&&-lymph node development-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0032355-&&-response to estradiol-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0009611-&&-response to wounding-%%-GO:1901666-&&-positive regulation of NAD+ ADP-ribosyltransferase activity-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0032667-&&-regulation of interleukin-23 production-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1990402-&&-embryonic liver development-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:1905005-&&-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0048565-&&-digestive tract development-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0001570-&&-vasculogenesis-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0002576-&&-platelet degranulation-%%-GO:0019049-&&-evasion or tolerance of host defenses by virus-%%-GO:0060325-&&-face morphogenesis-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0051101-&&-regulation of DNA binding-%%-GO:0010716-&&-negative regulation of extracellular matrix disassembly-%%-GO:0031536-&&-positive regulation of exit from mitosis-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0002248-&&-connective tissue replacement involved in inflammatory response wound healing-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0016477-&&-cell migration-%%-GO:0048839-&&-inner ear development-%%-GO:0097421-&&-liver regeneration-%%-GO:0060390-&&-regulation of SMAD protein import into nucleus-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:1903911-&&-positive regulation of receptor clustering-%%-GO:0045591-&&-positive regulation of regulatory T cell differentiation-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0016049-&&-cell growth-%%-GO:0001843-&&-neural tube closure-%%-GO:0009817-&&-defense response to fungus, incompatible interaction-%%-GO:0042482-&&-positive regulation of odontogenesis-%%-GO:0042493-&&-response to drug-%%-GO:0051098-&&-regulation of binding|cellular_component-&-1&-GO:0005796-&&-Golgi lumen-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0030424-&&-axon-%%-GO:0005576-&&-extracellular region-%%-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005634-&&-nucleus-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0034714-&&-type III transforming growth factor beta receptor binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0003823-&&-antigen binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity	G:9606:TGFB1	TGFB1	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05144-&&-Malaria-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05226-&&-Gastric cancer	TGFB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFB1	0.448044693	0.40646814	0.0295127	96	4	0.003536712	FALSE	4.791666667	TGFB1	TGFB1	68.45744681	5	0	95	0	0.75663043	FALSE	1	TGFB1	2492550	Infinity	0.02040862
789344	taxon:9606	2.32440523	428.4967319	2.70E-04	175693	1902	pre-mRNA processing factor 4	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006396-&&-RNA processing-%%-GO:0008380-&&-RNA splicing-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0071001-&&-U4/U6 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097525-&&-spliceosomal snRNP complex|molecular_function-&-1&-GO:0017070-&&-U6 snRNA binding-%%-GO:0030621-&&-U4 snRNA binding-%%-GO:0005515-&&-protein binding	G:9606:PRPF4			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF4	0.497210167	0.43021758	0.18142302	96	4	0.021305837	FALSE	21.74285714	PRPF4	PRPF4	209.0106383	22.58457039	0	95	0	0.77926579	FALSE	1	PRPF4	521066	Infinity	0.04969515
790036	taxon:9606	2.52906885	494.3040578	2.03E-04	174045	1902	centriolin	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051301-&&-cell division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:CNTRL				CNTRL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNTRL	0.458547742	0.39540244	0.08048246	96	4	0.005651468	FALSE	8.568627451	CNTRL	CNTRL	81.40625	9.057468386	0	96	0	0.74515519	FALSE	0	CNTRL	296606	Infinity	0.02781222
790244	taxon:9606	2.5090594	706.4448647	2.63E-04	173532	1902	RPGRIP1 like	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0021549-&&-cerebellum development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0043584-&&-nose development-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0043010-&&-camera-type eye development-%%-GO:0060039-&&-pericardium development-%%-GO:0001822-&&-kidney development-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0001889-&&-liver development-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0001736-&&-establishment of planar polarity-%%-GO:0022038-&&-corpus callosum development-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0021532-&&-neural tube patterning-%%-GO:0090102-&&-cochlea development|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005886-&&-plasma membrane-%%-GO:0005930-&&-axoneme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005929-&&-cilium-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005879-&&-axonemal microtubule-%%-GO:0005813-&&-centrosome-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005911-&&-cell-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031870-&&-thromboxane A2 receptor binding	G:9606:RPGRIP1L				RPGRIP1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPGRIP1L	0.466008135	0.39855573	0.05921053	96	4	0.005397907	FALSE	6.294117647	RPGRIP1L	RPGRIP1L	79.16666667	6.698307969	0	96	0	0.7484901	FALSE	0	RPGRIP1L	339572	Infinity	0.02583238
787224	taxon:9606	2.34614779	451.5203832	1.57E-04	179832	1902	minichromosome maintenance complex component 6	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0042555-&&-MCM complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:MCM6			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM6	0.498911353	0.42623061	0.25549322	95	4	0.024358617	FALSE	26.90909091	MCM6	MCM6	236.6774194	28.31595373	0	94	0	0.77564204	FALSE	1	MCM6	394466	Infinity	0.05795865
791463	taxon:9606	2.31321884	494.4174292	2.69E-04	168539	1902	WD repeat domain 77	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034709-&&-methylosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0005515-&&-protein binding	G:9606:WDR77				WDR77	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR77	0.49844624	0.43229805	0.13277232	95	4	0.019053636	FALSE	16.68181818	WDR77	WDR77	203	17.50557566	0	94	0	0.78113019	FALSE	1	WDR77	568164	Infinity	0.04735849
787570	taxon:9606	2.38411848	704.2863669	4.58E-04	179159	1902	NADH:ubiquinone oxidoreductase core subunit S3	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0045333-&&-cellular respiration-%%-GO:0021762-&&-substantia nigra development|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0016604-&&-nuclear body-%%-GO:0031966-&&-mitochondrial membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0003954-&&-NADH dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0009055-&&-electron carrier activity	G:9606:NDUFS3			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS3	0.478377572	0.41944224	0.14703132	95	4	0.009980005	FALSE	11.9375	NDUFS3	NDUFS3	142.0537634	13.7455432	0	94	0	0.76931359	FALSE	1	NDUFS3	696504	Infinity	0.03703299
792055	taxon:9606	2.43563888	295.1401745	5.74E-04	182683	1902	basigin (Ok blood group)	gene	biological_process-&-1&-GO:0043434-&&-response to peptide hormone-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0015718-&&-monocarboxylic acid transport-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0046689-&&-response to mercury ion-%%-GO:0046697-&&-decidualization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007566-&&-embryo implantation-%%-GO:0051591-&&-response to cAMP|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042383-&&-sarcolemma-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0005515-&&-protein binding-%%-GO:0008028-&&-monocarboxylic acid transmembrane transporter activity-%%-GO:0045296-&&-cadherin binding	G:9606:BSG				BSG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BSG	0.475259259	0.41056989	0.03856942	95	4	0.007545901	FALSE	6.194444444	BSG	BSG	101.516129	6.409663866	0	94	0	0.76072685	FALSE	1	BSG	630942	Infinity	0.02893986
792419	taxon:9606	2.26453443	547.0494817	4.36E-04	182054	1902	casein kinase 1 alpha 1	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051301-&&-cell division-%%-GO:0007030-&&-Golgi organization-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0006909-&&-phagocytosis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1904424-&&-regulation of GTP binding-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0008360-&&-regulation of cell shape|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005929-&&-cilium-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0016020-&&-membrane-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CSNK1A1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer-%%-hsa05165-&&-Human papillomavirus infection	CSNK1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1A1	0.499377335	0.44159187	0.10795073	95	4	0.013952938	FALSE	12.27868852	CSNK1A1	CSNK1A1	175	12.75110407	0	95	0	0.78924426	FALSE	0	CSNK1A1	665056	Infinity	0.03817167
788492	taxon:9606	2.43422089	659.413529	2.81E-04	177552	1902	small nuclear ribonucleoprotein polypeptides B and B1	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071004-&&-U2-type prespliceosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005685-&&-U1 snRNP-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005683-&&-U7 snRNP|molecular_function-&-1&-GO:0030620-&&-U2 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0071208-&&-histone pre-mRNA DCP binding	G:9606:SNRPB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa03040-&&-Spliceosome	SNRPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPB	0.485472155	0.41080906	0.13931744	95	4	0.017954163	FALSE	16.30555556	SNRPB	SNRPB	164.3548387	17.69000862	0	94	0	0.76096318	FALSE	1	SNRPB	474532	Infinity	0.04659803
792743	taxon:9606	2.27745392	956.9215216	5.74E-04	181458	1902	dynamin 2	gene	biological_process-&-1&-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0061025-&&-membrane fusion-%%-GO:0006897-&&-endocytosis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0003281-&&-ventricular septum development-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:1903526-&&-negative regulation of membrane tubulation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071245-&&-cellular response to carbon monoxide-%%-GO:0031623-&&-receptor internalization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0006909-&&-phagocytosis-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0035904-&&-aorta development-%%-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0009416-&&-response to light stimulus-%%-GO:1903358-&&-regulation of Golgi organization-%%-GO:0044351-&&-macropinocytosis-%%-GO:1903408-&&-positive regulation of sodium:potassium-exchanging ATPase activity-%%-GO:0042220-&&-response to cocaine-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0007165-&&-signal transduction-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0033572-&&-transferrin transport-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060976-&&-coronary vasculature development-%%-GO:1902856-&&-negative regulation of non-motile cilium assembly-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0048812-&&-neuron projection morphogenesis|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0005768-&&-endosome-%%-GO:0005874-&&-microtubule-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001891-&&-phagocytic cup|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031749-&&-D2 dopamine receptor binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:DNM2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04721-&&-Synaptic vesicle cycle	DNM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNM2	0.498601181	0.43908682	0.08846585	95	4	0.012736027	FALSE	10.19354839	DNM2	DNM2	169.0210526	11.16020221	0	95	0	0.78709101	FALSE	0	DNM2	852866	Infinity	0.03750788
793341	taxon:9606	2.32314479	722.0297525	4.50E-04	180269	1902	high mobility group box 1	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0043371-&&-negative regulation of CD4-positive, alpha-beta T cell differentiation-%%-GO:0050716-&&-positive regulation of interleukin-1 secretion-%%-GO:0032425-&&-positive regulation of mismatch repair-%%-GO:0034165-&&-positive regulation of toll-like receptor 9 signaling pathway-%%-GO:0001773-&&-myeloid dendritic cell activation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0050918-&&-positive chemotaxis-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0006914-&&-autophagy-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006310-&&-DNA recombination-%%-GO:0032072-&&-regulation of restriction endodeoxyribonuclease activity-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0045063-&&-T-helper 1 cell differentiation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0097350-&&-neutrophil clearance-%%-GO:0006265-&&-DNA topological change-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051106-&&-positive regulation of DNA ligation-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0033151-&&-V(D)J recombination-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0002840-&&-regulation of T cell mediated immune response to tumor cell-%%-GO:0006954-&&-inflammatory response-%%-GO:1990774-&&-tumor necrosis factor secretion-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0035711-&&-T-helper 1 cell activation-%%-GO:0002643-&&-regulation of tolerance induction-%%-GO:0017055-&&-negative regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0032392-&&-DNA geometric change-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0031175-&&-neuron projection development-%%-GO:0043410-&&-positive regulation of MAPK cascade|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0000793-&&-condensed chromosome|molecular_function-&-1&-GO:0000405-&&-bubble DNA binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0097100-&&-supercoiled DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0016829-&&-lyase activity-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0019958-&&-C-X-C chemokine binding	G:9606:HMGB1	HMGB1	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa03410-&&-Base excision repair-%%-hsa04217-&&-Necroptosis	HMGB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGB1	0.498291395	0.430451	0.0837626	95	4	0.01273952	FALSE	9.936507937	HMGB1	HMGB1	153.7684211	10.37602419	0	95	0	0.77947587	FALSE	0	HMGB1	663332	Infinity	0.03652692
789320	taxon:9606	2.36568458	858.1560527	4.18E-04	175747	1902	MAGE family member D1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000785-&&-chromatin-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding	G:9606:MAGED1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	MAGED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGED1	0.492931776	0.42271062	0.06241234	95	4	0.00973137	FALSE	8.637931034	MAGED1	MAGED1	125	9.523583478	0	94	0	0.7723859	FALSE	1	MAGED1	536512	Infinity	0.03161067
789379	taxon:9606	2.35512841	405.2510985	2.20E-04	175621	1902	metastasis associated 1 family member 2	gene	biological_process-&-1&-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006306-&&-DNA methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006333-&&-chromatin assembly or disassembly-%%-GO:0016575-&&-histone deacetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016020-&&-membrane-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding	G:9606:MTA2				MTA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTA2	0.494298921	0.4246053	0.18118701	95	4	0.017801557	FALSE	18.77272727	MTA2	MTA2	196.1894737	19.63048289	0	95	0	0.77414527	FALSE	0	MTA2	489548	Infinity	0.04852051
787261	taxon:9606	2.32440523	433.4810562	6.61E-04	179784	1902	Janus kinase 1	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:1903672-&&-positive regulation of sprouting angiogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0038110-&&-interleukin-2-mediated signaling pathway-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0046677-&&-response to antibiotic-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005131-&&-growth hormone receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0031730-&&-CCR5 chemokine receptor binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:JAK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	JAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAK1	0.488428745	0.43021758	0.13043478	94	4	0.009734989	FALSE	14.25	JAK1	JAK1	135.8586957	15.07221225	0	93	0	0.77926579	FALSE	1	JAK1	824476	Infinity	0.03225257
791805	taxon:9606	2.44524972	856.7150281	3.41E-04	166787	1902	leucine zipper tumor suppressor 2	gene	biological_process-&-1&-GO:0001822-&&-kidney development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1900181-&&-negative regulation of protein localization to nucleus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:LZTS2				LZTS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LZTS2	0.475400119	0.40895619	0.03568977	94	4	0.006591888	FALSE	4.1	LZTS2	LZTS2	95.81914894	4.451284983	0	94	0	0.75912505	FALSE	0	LZTS2	485956	Infinity	0.02773358
787773	taxon:9606	2.40712147	702.1663326	2.52E-04	178806	1902	protein phosphatase, Mg2+/Mn2+ dependent 1G	gene	biological_process-&-1&-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity	G:9606:PPM1G				PPM1G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPM1G	0.496133622	0.41543396	0.10867078	94	4	0.014972605	FALSE	11.55223881	PPM1G	PPM1G	157.5851064	12.3704984	0	94	0	0.76547975	FALSE	0	PPM1G	475926	Infinity	0.04259058
787837	taxon:9606	2.32219946	879.5878326	4.38E-04	178732	1902	mitogen-activated protein kinase kinase 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0007507-&&-heart development-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0030878-&&-thyroid gland development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0021697-&&-cerebellar cortex formation-%%-GO:0048679-&&-regulation of axon regeneration-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0035897-&&-proteolysis in other organism-%%-GO:0060324-&&-face development-%%-GO:0060502-&&-epithelial cell proliferation involved in lung morphogenesis-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:1903800-&&-positive regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0048538-&&-thymus development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0048870-&&-cell motility-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006935-&&-chemotaxis-%%-GO:0060711-&&-labyrinthine layer development-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0060440-&&-trachea formation-%%-GO:0090398-&&-cellular senescence|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005770-&&-late endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004728-&&-signal transducer, downstream of receptor, with protein tyrosine phosphatase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:MAP2K1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05020-&&-Prion diseases-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	MAP2K1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K1	0.489173529	0.43062623	0.09173435	94	4	0.009811879	FALSE	11.50819672	MAP2K1	MAP2K1	141.2717391	12.58048819	0	93	0	0.77963342	FALSE	1	MAP2K1	632920	Infinity	0.03335319
788229	taxon:9606	2.43878998	327.6081033	0.00122828	178040	1902	small glutamine rich tetratricopeptide repeat containing alpha	gene	biological_process-&-1&-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1903070-&&-negative regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0008150-&&-biological_process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:1904288-&&-BAT3 complex binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding	G:9606:SGTA				SGTA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGTA	0.474556213	0.41003941	0.03917821	94	4	0.006906619	FALSE	7.675	SGTA	SGTA	92.26086957	7.920776108	0	93	0	0.76020167	FALSE	1	SGTA	1314576	Infinity	0.02649672
792631	taxon:9606	2.34961399	726.2191492	3.78E-04	181686	1902	eukaryotic translation elongation factor 1 alpha 2	gene	biological_process-&-1&-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0006414-&&-translational elongation-%%-GO:0090218-&&-positive regulation of lipid kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0010035-&&-response to inorganic substance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0098574-&&-cytoplasmic side of lysosomal membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:EEF1A2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05134-&&-Legionellosis	EEF1A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1A2	0.501093408	0.42560182	0.11988103	94	4	0.020066015	FALSE	13.43589744	EEF1A2	EEF1A2	186.0106383	14.17436388	0	94	0	0.77506433	FALSE	0	EEF1A2	569120	Infinity	0.04597828
792768	taxon:9606	2.32062392	491.6645337	2.53E-04	181411	1902	DNA methyltransferase 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006306-&&-DNA methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0090309-&&-positive regulation of methylation-dependent chromatin silencing-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0090116-&&-C-5 methylation of cytosine-%%-GO:0016458-&&-gene silencing-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005721-&&-pericentric heterochromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003886-&&-DNA (cytosine-5-)-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:DNMT1			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05206-&&-MicroRNAs in cancer	DNMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT1	0.498911353	0.4309186	0.22216914	94	4	0.018535217	FALSE	25.5	DNMT1	DNMT1	203.9021739	27.05956798	0	93	0	0.77989601	FALSE	1	DNMT1	481032	Infinity	0.04808501
788798	taxon:9606	2.29998424	630.1879648	3.27E-04	176848	1902	tubulin beta 2A class IIa	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB2A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB2A	0.499377335	0.43478559	0.09723175	94	4	0.015161509	FALSE	11.46153846	TUBB2A	TUBB2A	169.5531915	12.01332676	0	94	0	0.78333596	FALSE	0	TUBB2A	607196	Infinity	0.03885185
788962	taxon:9606	2.4244525	440.3102245	5.93E-04	176527	1902	phosphoinositide-3-kinase regulatory subunit 3	gene	biological_process-&-1&-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0008286-&&-insulin receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex|molecular_function-&-1&-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity	G:9606:PIK3R3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3R3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R3	0.466821886	0.41246426	0.08670785	94	4	0.005831408	FALSE	11.25	PIK3R3	PIK3R3	100.9042553	11.59275138	0	94	0	0.76259125	FALSE	0	PIK3R3	633648	Infinity	0.02820698
793366	taxon:9606	2.34346936	421.3113665	2.15E-04	180235	1902	heterogeneous nuclear ribonucleoprotein H2	gene	biological_process-&-1&-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPH2				HNRNPH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPH2	0.498756219	0.42671776	0.23315815	94	4	0.023251981	FALSE	26.22972973	HNRNPH2	HNRNPH2	207.9565217	27.25236681	0	93	0	0.77608844	FALSE	1	HNRNPH2	386332	Infinity	0.05079988
789697	taxon:9606	2.27414527	505.3134245	1.54E-04	174870	1902	MYB binding protein 1a	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0071897-&&-DNA biosynthetic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042564-&&-NLS-dependent protein nuclear import complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding	G:9606:MYBBP1A				MYBBP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYBBP1A	0.502663742	0.43972565	0.2736216	94	4	0.028501056	FALSE	27.45783133	MYBBP1A	MYBBP1A	254.5744681	28.82039242	0	94	0	0.78764246	FALSE	0	MYBBP1A	425612	Infinity	0.05623235
789734	taxon:9606	2.48857728	639.9457561	1.31E-04	174799	1902	chromatin assembly factor 1 subunit A	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0031497-&&-chromatin assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007049-&&-cell cycle-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0033186-&&-CAF-1 complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0070087-&&-chromo shadow domain binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CHAF1A				CHAF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHAF1A	0.48591336	0.40183602	0.21118012	94	4	0.020305172	FALSE	23.675	CHAF1A	CHAF1A	183.25	25.19861508	0	93	0	0.75190379	FALSE	1	CHAF1A	311954	Infinity	0.05723415
789831	taxon:9606	2.44966126	773.2727399	1.79E-04	174544	1902	euchromatic histone lysine methyltransferase 2	gene	biological_process-&-1&-GO:0006306-&&-DNA methylation-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0009267-&&-cellular response to starvation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016571-&&-histone methylation-%%-GO:0070734-&&-histone H3-K27 methylation-%%-GO:0051567-&&-histone H3-K9 methylation-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0018027-&&-peptidyl-lysine dimethylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046974-&&-histone methyltransferase activity (H3-K9 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0046976-&&-histone methyltransferase activity (H3-K27 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0002039-&&-p53 binding-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:EHMT2			KEGG-&-1&-hsa00310-&&-Lysine degradation-%%-hsa04211-&&-Longevity regulating pathway	EHMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHMT2	0.48009578	0.40821971	0.16817965	94	4	0.013959594	FALSE	17.8115942	EHMT2	EHMT2	159.5652174	19.2650772	0	93	0	0.75838979	FALSE	1	EHMT2	404510	Infinity	0.04635912
790063	taxon:9606	2.5853159	268.0858021	1.65E-04	173970	1902	protein tyrosine phosphatase type IVA, member 3	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:1900746-&&-regulation of vascular endothelial growth factor signaling pathway-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0043117-&&-positive regulation of vascular permeability|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0004727-&&-prenylated protein tyrosine phosphatase activity	G:9606:PTP4A3				PTP4A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTP4A3	0.450056117	0.38679993	0.02150024	94	4	0.005951378	FALSE	4.634146341	PTP4A3	PTP4A3	72.7173913	4.774145299	0	93	0	0.73578068	FALSE	1	PTP4A3	260390	Infinity	0.0282974
790924	taxon:9606	2.41436899	334.6485558	1.12E-04	170694	1902	NOP58 ribonucleoprotein	gene	biological_process-&-1&-GO:0016049-&&-cell growth-%%-GO:0048254-&&-snoRNA localization-%%-GO:0006608-&&-snRNP protein import into nucleus-%%-GO:0006364-&&-rRNA processing-%%-GO:0000154-&&-rRNA modification|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005732-&&-small nucleolar ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0070761-&&-pre-snoRNP complex|molecular_function-&-1&-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:NOP58			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NOP58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP58	0.489322758	0.4141869	0.27325853	93	4	0.02258865	FALSE	27.06944444	NOP58	NOP58	193.2795699	28.51501278	0	93	0	0.76427183	FALSE	0	NOP58	258676	Infinity	0.05284313
790916	taxon:9606	2.39908618	734.2305369	2.81E-04	170701	1902	protein inhibitor of activated STAT 4	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016925-&&-protein sumoylation-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1902174-&&-positive regulation of keratinocyte apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body-%%-GO:0005737-&&-cytoplasm-%%-GO:1990234-&&-transferase complex-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0019789-&&-SUMO transferase activity-%%-GO:0061665-&&-SUMO ligase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PIAS4			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04064-&&-NF-kappa B signaling pathway	PIAS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS4	0.487093835	0.41682538	0.0972417	93	4	0.010098746	FALSE	10.77777778	PIAS4	PIAS4	127.0322581	11.62043797	0	93	0	0.76681897	FALSE	0	PIAS4	436924	Infinity	0.03387283
787313	taxon:9606	2.32928943	928.3124603	2.03E-04	179677	1902	importin 5	gene	biological_process-&-1&-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0003723-&&-RNA binding	G:9606:IPO5				IPO5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO5	0.500311915	0.42931548	0.1313698	93	4	0.017470473	FALSE	13.8115942	IPO5	IPO5	189.7526882	15.07964998	0	93	0	0.77845176	FALSE	0	IPO5	419620	Infinity	0.04533857
787454	taxon:9606	2.43296045	498.1789319	2.15E-04	179401	1902	menin 1	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0061469-&&-regulation of type B pancreatic cell proliferation-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0009411-&&-response to UV-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0046697-&&-decidualization-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0002076-&&-osteoblast development-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0003309-&&-type B pancreatic cell differentiation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0006281-&&-DNA repair-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007420-&&-brain development-%%-GO:0010332-&&-response to gamma radiation-%%-GO:1902807-&&-negative regulation of cell cycle G1/S phase transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071375-&&-cellular response to peptide hormone stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000785-&&-chromatin-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0032154-&&-cleavage furrow|molecular_function-&-1&-GO:0000403-&&-Y-form DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0070412-&&-R-SMAD binding	G:9606:MEN1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04934-&&-Cushing syndrome	MEN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEN1	0.485766202	0.41102189	0.1659654	93	4	0.019279981	FALSE	16.76712329	MEN1	MEN1	200.8602151	17.67536585	0	93	0	0.76117326	FALSE	0	MEN1	475802	Infinity	0.0565523
787700	taxon:9606	2.28722231	747.0418329	2.65E-04	178923	1902	plectin	gene	biological_process-&-1&-GO:0031581-&&-hemidesmosome assembly|cellular_component-&-1&-GO:0016528-&&-sarcoplasm-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005903-&&-brush border-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042383-&&-sarcolemma-%%-GO:0043034-&&-costamere-%%-GO:0030056-&&-hemidesmosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0030506-&&-ankyrin binding-%%-GO:0003723-&&-RNA binding	G:9606:PLEC				PLEC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLEC	0.50297899	0.43721155	0.13207106	93	4	0.019328168	FALSE	14.52777778	PLEC	PLEC	211.2688172	15.38992732	0	93	0	0.78546295	FALSE	0	PLEC	546780	Infinity	0.04759724
787995	taxon:9606	2.37214432	561.1768555	4.49E-04	178438	1902	platelet derived growth factor receptor beta	gene	biological_process-&-1&-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0060326-&&-cell chemotaxis-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0043627-&&-response to estrogen-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0046488-&&-phosphatidylinositol metabolic process-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0072277-&&-metanephric glomerular capillary formation-%%-GO:0060437-&&-lung growth-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0072284-&&-metanephric S-shaped body morphogenesis-%%-GO:0035789-&&-metanephric mesenchymal cell migration-%%-GO:0042060-&&-wound healing-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0060981-&&-cell migration involved in coronary angiogenesis-%%-GO:0072278-&&-metanephric comma-shaped body morphogenesis-%%-GO:0071670-&&-smooth muscle cell chemotaxis-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0035793-&&-positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0016477-&&-cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0072262-&&-metanephric glomerular mesangial cell proliferation involved in metanephros development-%%-GO:0007568-&&-aging-%%-GO:0008584-&&-male gonad development-%%-GO:0032355-&&-response to estradiol-%%-GO:0038091-&&-positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0035441-&&-cell migration involved in vasculogenesis-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0048839-&&-inner ear development-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0072075-&&-metanephric mesenchyme development-%%-GO:0061298-&&-retina vasculature development in camera-type eye|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031226-&&-intrinsic component of plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005017-&&-platelet-derived growth factor-activated receptor activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005019-&&-platelet-derived growth factor beta-receptor activity-%%-GO:0038085-&&-vascular endothelial growth factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004992-&&-platelet activating factor receptor activity-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0019901-&&-protein kinase binding	G:9606:PDGFRB			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton	PDGFRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFRB	0.477380952	0.42155951	0.13797314	93	4	0.006882692	FALSE	17.42372881	PDGFRB	PDGFRB	121.7142857	19.7041694	0	92	0	0.77130928	FALSE	1	PDGFRB	516824	Infinity	0.0311182
792303	taxon:9606	2.40223728	317.9048694	3.64E-04	182259	1902	CCAAT/enhancer binding protein alpha	gene	biological_process-&-1&-GO:0000050-&&-urea cycle-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0048839-&&-inner ear development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0001889-&&-liver development-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0016032-&&-viral process-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0048469-&&-cell maturation-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0030324-&&-lung development|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019900-&&-kinase binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:CEBPA			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	CEBPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPA	0.484738592	0.41627861	0.13382173	93	4	0.01033175	FALSE	16.22222222	CEBPA	CEBPA	132.7252747	17.12611106	0	92	0	0.76629379	FALSE	1	CEBPA	504940	Infinity	0.03554281
788571	taxon:9606	2.41941075	569.2180754	3.04E-04	177413	1902	TATA-box binding protein associated factor 9	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0000492-&&-box C/D snoRNP assembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0060760-&&-positive regulation of response to cytokine stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0000125-&&-PCAF complex-%%-GO:0070761-&&-pre-snoRNP complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0002039-&&-p53 binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0003677-&&-DNA binding	G:9606:TAF9			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF9	0.475541061	0.41332378	0.1201496	93	4	0.013570204	FALSE	11.28333333	TAF9	TAF9	137.8064516	11.99852396	0	93	0	0.76343154	FALSE	0	TAF9	469808	Infinity	0.0380594
788768	taxon:9606	2.41106034	902.4638234	3.63E-04	176944	1902	zyxin	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0016032-&&-viral process-%%-GO:0050727-&&-regulation of inflammatory response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005634-&&-nucleus-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:ZYX			KEGG-&-1&-hsa04510-&&-Focal adhesion	ZYX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZYX	0.490970309	0.41475528	0.08578775	93	4	0.013770705	FALSE	8.830769231	ZYX	ZYX	142.9247312	9.776856622	0	93	0	0.76482328	FALSE	0	ZYX	576390	Infinity	0.0389884
788996	taxon:9606	2.43989286	467.4657959	2.31E-04	160051	1902	glutathione S-transferase kappa 1	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0030855-&&-epithelial cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005622-&&-intracellular-%%-GO:0005777-&&-peroxisome-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0005515-&&-protein binding	G:9606:GSTK1			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05204-&&-Chemical carcinogenesis	GSTK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTK1	0.473995272	0.40985406	0.05323565	93	4	0.008841943	FALSE	8.14893617	GSTK1	GSTK1	105.967033	8.497088118	0	92	0	0.76001786	FALSE	1	GSTK1	340196	Infinity	0.03039883
789955	taxon:9606	2.34189381	618.6458158	1.99E-04	174255	1902	heat shock protein family H (Hsp110) member 1	gene	biological_process-&-1&-GO:1903753-&&-negative regulation of p38MAPK cascade-%%-GO:1903748-&&-negative regulation of establishment of protein localization to mitochondrion-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1903751-&&-negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0051135-&&-positive regulation of NK T cell activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity	G:9606:HSPH1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPH1	0.499688474	0.42700484	0.13931744	93	4	0.01740988	FALSE	13.65753425	HSPH1	HSPH1	180.2795699	14.56452629	0	93	0	0.77635103	FALSE	0	HSPH1	410642	Infinity	0.04380773
790423	taxon:9606	2.42350717	502.1661643	2.13E-04	173032	1902	FtsJ RNA methyltransferase homolog 1 (E. coli)	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0030488-&&-tRNA methylation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0052666-&&-tRNA (cytosine-2'-O-)-methyltransferase activity-%%-GO:0009020-&&-tRNA (guanosine-2'-O-)-methyltransferase activity	G:9606:FTSJ1				FTSJ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FTSJ1	0.481826374	0.41262515	0.04908836	93	4	0.009844804	FALSE	6.625	FTSJ1	FTSJ1	109.3225807	6.862700561	0	93	0	0.76274881	FALSE	0	FTSJ1	340912	Infinity	0.03051504
787245	taxon:9606	2.2569718	732.9087959	3.52E-04	179805	1902	insulin receptor substrate 1	gene	biological_process-&-1&-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0032868-&&-response to insulin-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola-%%-GO:0005737-&&-cytoplasm-%%-GO:0005899-&&-insulin receptor complex|molecular_function-&-1&-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0004871-&&-signal transducer activity	G:9606:IRS1	IRS1	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04022-&&-cGMP-PKG signaling pathway	IRS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRS1	0.498136646	0.44307155	0.16254682	92	4	0.012042376	FALSE	17.08695652	IRS1	IRS1	180.2555556	19.53015865	0	91	0	0.7905047	FALSE	1	IRS1	570238	Infinity	0.0388793
787303	taxon:9606	2.60847645	188.8570806	2.65E-04	179699	1902	KIT proto-oncogene receptor tyrosine kinase	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0050910-&&-detection of mechanical stimulus involved in sensory perception of sound-%%-GO:0008584-&&-male gonad development-%%-GO:0032762-&&-mast cell cytokine production-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1905065-&&-positive regulation of vascular smooth muscle cell differentiation-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002371-&&-dendritic cell cytokine production-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0043473-&&-pigmentation-%%-GO:0097326-&&-melanocyte adhesion-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0038093-&&-Fc receptor signaling pathway-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0060374-&&-mast cell differentiation-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0002318-&&-myeloid progenitor cell differentiation-%%-GO:0002551-&&-mast cell chemotaxis-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0007286-&&-spermatid development-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0002327-&&-immature B cell differentiation-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0097324-&&-melanocyte migration-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0007283-&&-spermatogenesis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0048103-&&-somatic stem cell division-%%-GO:0008542-&&-visual learning-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0035701-&&-hematopoietic stem cell migration-%%-GO:0008354-&&-germ cell migration-%%-GO:0030217-&&-T cell differentiation-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048170-&&-positive regulation of long-term neuronal synaptic plasticity-%%-GO:0048565-&&-digestive tract development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0038162-&&-erythropoietin-mediated signaling pathway-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0002320-&&-lymphoid progenitor cell differentiation-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0048070-&&-regulation of developmental pigmentation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0038109-&&-Kit signaling pathway-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0030097-&&-hemopoiesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070662-&&-mast cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005911-&&-cell-cell junction-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0042629-&&-mast cell granule|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019955-&&-cytokine binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005020-&&-stem cell factor receptor activity	G:9606:KIT			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage	KIT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIT	0.42796158	0.38336555	0.13882647	92	4	0.00446001	FALSE	15.69767442	KIT	KIT	83.15555556	16.23435468	0	91	0	0.73192059	FALSE	1	KIT	324420	Infinity	0.03426804
791551	taxon:9606	2.39829841	665.2195787	2.95E-04	168062	1902	cell division cycle 73	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0034402-&&-recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex-%%-GO:0031648-&&-protein destabilization-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007049-&&-cell cycle-%%-GO:0048147-&&-negative regulation of fibroblast proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016593-&&-Cdc73/Paf1 complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:CDC73	CDC73	TRUE		CDC73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC73	0.484007242	0.41696229	0.11801242	92	4	0.011932868	FALSE	11.61818182	CDC73	CDC73	148.923913	12.51808436	0	92	0	0.76695027	FALSE	0	CDC73	524280	Infinity	0.03973224
787458	taxon:9606	2.51945801	817.0428997	9.86E-04	179399	1902	mesenchyme homeobox 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0070997-&&-neuron death-%%-GO:0060021-&&-palate development-%%-GO:0060173-&&-limb development-%%-GO:0001525-&&-angiogenesis-%%-GO:0001757-&&-somite specification-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008015-&&-blood circulation-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0061053-&&-somite development|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:MEOX2				MEOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEOX2	0.457631954	0.39691076	0.03081701	92	4	0.004732838	FALSE	3.974358974	MEOX2	MEOX2	72.33695652	4.784790554	0	92	0	0.746757	FALSE	0	MEOX2	1129696	Infinity	0.0244252
791928	taxon:9606	2.28611943	523.703409	3.40E-04	182860	1902	aldolase, fructose-bisphosphate A	gene	biological_process-&-1&-GO:0030388-&&-fructose 1,6-bisphosphate metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006096-&&-glycolytic process-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007015-&&-actin filament organization-%%-GO:0006754-&&-ATP biosynthetic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031674-&&-I band-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:0031430-&&-M band-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0004332-&&-fructose-bisphosphate aldolase activity-%%-GO:0070061-&&-fructose binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0003779-&&-actin binding-%%-GO:0008092-&&-cytoskeletal protein binding	G:9606:ALDOA			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa00030-&&-Pentose phosphate pathway	ALDOA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDOA	0.499066584	0.43742247	0.14906367	92	4	0.016038546	FALSE	17.453125	ALDOA	ALDOA	188.4666667	18.88710402	0	91	0	0.78564676	FALSE	1	ALDOA	569138	Infinity	0.04230405
791943	taxon:9606	2.42082874	495.2807464	2.82E-04	182831	1902	autocrine motility factor receptor	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007611-&&-learning or memory-%%-GO:0007568-&&-aging-%%-GO:0051259-&&-protein oligomerization-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0036503-&&-ERAD pathway|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0004872-&&-receptor activity-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:1904288-&&-BAT3 complex binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:AMFR			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	AMFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMFR	0.484299517	0.41308168	0.13558052	92	4	0.010473823	FALSE	15.31746032	AMFR	AMFR	127.7666667	16.42178693	0	91	0	0.76319521	FALSE	1	AMFR	400576	Infinity	0.03540589
792984	taxon:9606	2.34142114	507.7170914	2.67E-04	181040	1902	filamin B	gene	biological_process-&-1&-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0003334-&&-keratinocyte development-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007519-&&-skeletal muscle tissue development|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:FLNB			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	FLNB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLNB	0.494756323	0.42709104	0.10811486	92	4	0.015532636	FALSE	13.91935484	FLNB	FLNB	181.6777778	14.5783781	0	91	0	0.77642981	FALSE	1	FLNB	498026	Infinity	0.04421725
793092	taxon:9606	2.41090279	912.7798268	2.13E-04	180747	1902	glycyl-tRNA synthetase	gene	biological_process-&-1&-GO:0015966-&&-diadenosine tetraphosphate biosynthetic process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006426-&&-glycyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0030141-&&-secretory granule-%%-GO:0030424-&&-axon|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004820-&&-glycine-tRNA ligase activity-%%-GO:0004081-&&-bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:GARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	GARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GARS	0.49066993	0.41478238	0.12637363	92	4	0.014197907	FALSE	10.92537313	GARS	GARS	150.4673913	11.98938633	0	92	0	0.76484954	FALSE	0	GARS	390190	Infinity	0.04093759
789314	taxon:9606	2.52134867	665.150098	2.64E-04	175764	1902	mediator complex subunit 20	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED20				MED20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED20	0.463851938	0.39661314	0.09149546	92	4	0.005923173	FALSE	6.673469388	MED20	MED20	82.76086957	7.369726857	0	92	0	0.74644189	FALSE	0	MED20	332064	Infinity	0.02775628
789652	taxon:9606	2.41562943	772.0946824	2.21E-04	174969	1902	N-myc downstream regulated 1	gene	biological_process-&-1&-GO:0071456-&&-cellular response to hypoxia-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:0010038-&&-response to metal ion-%%-GO:0045576-&&-mast cell activation-%%-GO:0090232-&&-positive regulation of spindle checkpoint|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0043015-&&-gamma-tubulin binding	G:9606:NDRG1				NDRG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDRG1	0.493690366	0.41397078	0.0931677	92	4	0.017020795	FALSE	9.928571429	NDRG1	NDRG1	144.8695652	10.38081831	0	92	0	0.76406176	FALSE	0	NDRG1	368584	Infinity	0.03972983
791887	taxon:9606	2.34677801	548.5094727	1.54E-04	166536	1902	ubiquitin associated and SH3 domain containing B	gene	biological_process-&-1&-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBASH3B				UBASH3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBASH3B	0.493994456	0.42611615	0.13355465	91	4	0.013992961	FALSE	15.01515152	UBASH3B	UBASH3B	162.9213483	15.90804669	0	90	0	0.775537	FALSE	1	UBASH3B	326744	Infinity	0.04001877
787898	taxon:9606	2.42539783	874.1932131	1.61E-04	178641	1902	proteasome 26S subunit, non-ATPase 7	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:PSMD7			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD7	0.491421569	0.41230349	0.29279609	91	4	0.011153231	FALSE	28.15068493	PSMD7	PSMD7	138.1758242	30.58898779	0	91	0	0.7624337	FALSE	0	PSMD7	308730	Infinity	0.03852283
788680	taxon:9606	2.5125256	450.4037258	4.50E-04	177210	1902	transducin like enhancer of split 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TLE1				TLE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLE1	0.465872785	0.39800589	0.06435138	91	4	0.010666555	FALSE	10.16666667	TLE1	TLE1	119.1685393	10.54192144	0	90	0	0.7479124	FALSE	1	TLE1	631812	Infinity	0.03907115
789646	taxon:9606	2.31794549	554.6963682	3.57E-04	174983	1902	tubulin beta 4A class IVa	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005929-&&-cilium-%%-GO:0033269-&&-internode region of axon-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB4A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB4A	0.498756219	0.43141653	0.0957265	91	4	0.015330076	FALSE	11.20289855	TUBB4A	TUBB4A	176.5824176	11.79841825	0	91	0	0.78034242	FALSE	0	TUBB4A	649884	Infinity	0.04152812
789848	taxon:9606	2.33370096	381.0214109	9.14E-05	174518	1902	heterogeneous nuclear ribonucleoprotein A0	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0006954-&&-inflammatory response-%%-GO:0006397-&&-mRNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:HNRNPA0				HNRNPA0	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA0	0.500936914	0.42850392	0.30647131	91	4	0.027416198	FALSE	30.6625	HNRNPA0	HNRNPA0	249.3516484	31.94356609	0	91	0	0.77771651	FALSE	0	HNRNPA0	253782	Infinity	0.05992589
787088	taxon:9606	2.38254293	330.041195	4.60E-04	180088	1902	recombination signal binding protein for immunoglobulin kappa J region	gene	biological_process-&-1&-GO:0060486-&&-Clara cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0009912-&&-auditory receptor cell fate commitment-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:1901186-&&-positive regulation of ERBB signaling pathway-%%-GO:0048820-&&-hair follicle maturation-%%-GO:0009957-&&-epidermal cell fate specification-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0006959-&&-humoral immune response-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0048505-&&-regulation of timing of cell differentiation-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003214-&&-cardiac left ventricle morphogenesis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0048733-&&-sebaceous gland development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901297-&&-positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0060844-&&-arterial endothelial cell fate commitment-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0007221-&&-positive regulation of transcription of Notch receptor target-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0001756-&&-somitogenesis-%%-GO:0003256-&&-regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:2000138-&&-positive regulation of cell proliferation involved in heart morphogenesis-%%-GO:0072554-&&-blood vessel lumenization-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0021983-&&-pituitary gland development-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0072602-&&-interleukin-4 secretion-%%-GO:1901189-&&-positive regulation of ephrin receptor signaling pathway-%%-GO:0030183-&&-B cell differentiation-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0006310-&&-DNA recombination-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0003160-&&-endocardium morphogenesis-%%-GO:0097101-&&-blood vessel endothelial cell fate specification-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0002193-&&-MAML1-RBP-Jkappa- ICN1 complex|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000150-&&-recombinase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:RBPJ			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection	RBPJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBPJ	0.479665072	0.41971961	0.05867665	90	4	0.008197976	FALSE	6.931818182	RBPJ	RBPJ	118.1555556	7.188338093	0	90	0	0.76957618	FALSE	0	RBPJ	553524	Infinity	0.03056634
787298	taxon:9606	2.36048527	822.6602586	3.02E-04	179714	1902	kinesin family member 5B	gene	biological_process-&-1&-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:1905152-&&-positive regulation of voltage-gated sodium channel activity-%%-GO:0072383-&&-plus-end-directed vesicle transport along microtubule-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0032230-&&-positive regulation of synaptic transmission, GABAergic-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0007028-&&-cytoplasm organization-%%-GO:0035617-&&-stress granule disassembly-%%-GO:0007411-&&-axon guidance-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0051642-&&-centrosome localization|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005871-&&-kinesin complex-%%-GO:0016020-&&-membrane-%%-GO:0044295-&&-axonal growth cone|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0008432-&&-JUN kinase binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed-%%-GO:0045296-&&-cadherin binding	G:9606:KIF5B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04728-&&-Dopaminergic synapse	KIF5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF5B	0.49644073	0.4236417	0.08963795	90	4	0.012741446	FALSE	8.5	KIF5B	KIF5B	157.8333333	9.01692735	0	90	0	0.77325246	FALSE	0	KIF5B	494004	Infinity	0.03949937
787866	taxon:9606	2.38774224	569.2900534	4.90E-04	178683	1902	presenilin 1	gene	biological_process-&-1&-GO:0051563-&&-smooth endoplasmic reticulum calcium ion homeostasis-%%-GO:0021795-&&-cerebral cortex cell migration-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0015031-&&-protein transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0015871-&&-choline transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001708-&&-cell fate specification-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048538-&&-thymus development-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0048666-&&-neuron development-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0015813-&&-L-glutamate transport-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0007220-&&-Notch receptor processing-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0007613-&&-memory-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0003407-&&-neural retina development-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0009791-&&-post-embryonic development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0021870-&&-Cajal-Retzius cell differentiation-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0050820-&&-positive regulation of coagulation-%%-GO:0042982-&&-amyloid precursor protein metabolic process-%%-GO:0001764-&&-neuron migration-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001568-&&-blood vessel development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0034205-&&-beta-amyloid formation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0016080-&&-synaptic vesicle targeting-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0016485-&&-protein processing-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0006486-&&-protein glycosylation-%%-GO:0060075-&&-regulation of resting membrane potential-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0002286-&&-T cell activation involved in immune response-%%-GO:0001756-&&-somitogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0050771-&&-negative regulation of axonogenesis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0045121-&&-membrane raft-%%-GO:0000776-&&-kinetochore-%%-GO:0043198-&&-dendritic shaft-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005813-&&-centrosome-%%-GO:0030018-&&-Z disc-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0030426-&&-growth cone-%%-GO:0016235-&&-aggresome-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0070765-&&-gamma-secretase complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042500-&&-aspartic endopeptidase activity, intramembrane cleaving-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005262-&&-calcium channel activity	G:9606:PSEN1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa05165-&&-Human papillomavirus infection	PSEN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSEN1	0.480383348	0.41880567	0.06713689	90	4	0.006826891	FALSE	8.1	PSEN1	PSEN1	106.2045455	8.601292628	0	89	0	0.76870963	FALSE	1	PSEN1	587990	Infinity	0.02783972
791958	taxon:9606	2.30833465	1867.912889	4.75E-04	182805	1902	solute carrier family 25 member 6	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0006915-&&-apoptotic process-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0055085-&&-transmembrane transport-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0046732-&&-active induction of host immune response by virus-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0015867-&&-ATP transport-%%-GO:0015866-&&-ADP transport|cellular_component-&-1&-GO:0005744-&&-mitochondrial inner membrane presequence translocase complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0015207-&&-adenine transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005471-&&-ATP:ADP antiporter activity	G:9606:SLC25A6			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05016-&&-Huntington disease-%%-hsa04218-&&-Cellular senescence-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SLC25A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A6	0.501720363	0.43321275	0.06766542	90	4	0.015709523	FALSE	7.628571429	SLC25A6	SLC25A6	181.8777778	8.255979482	0	90	0	0.78194423	FALSE	0	SLC25A6	835838	Infinity	0.04217324
787879	taxon:9606	2.37119899	668.9716077	1.52E-04	178660	1902	proteasome subunit beta 5	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0006508-&&-proteolysis-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB5			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB5	0.49751861	0.42172757	0.29937578	90	4	0.01330375	FALSE	28.21333333	PSMB5	PSMB5	157.1888889	30.63393204	0	90	0	0.77146683	FALSE	0	PSMB5	329088	Infinity	0.04007876
787914	taxon:9606	2.68016386	381.2334237	7.56E-04	178622	1902	prostaglandin E receptor 3	gene	biological_process-&-1&-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0060455-&&-negative regulation of gastric acid secretion-%%-GO:0008219-&&-cell death-%%-GO:0014827-&&-intestine smooth muscle contraction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0031622-&&-positive regulation of fever generation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0004957-&&-prostaglandin E receptor activity	G:9606:PTGER3	PTGER3	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	PTGER3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGER3	0.390647832	0.37311152	0.01822722	90	4	0.001579299	FALSE	3.692307692	PTGER3	PTGER3	45.43333333	3.985755694	0	90	0	0.71997269	FALSE	0	PTGER3	714972	Infinity	0.02304358
792477	taxon:9606	2.42161651	759.4709852	6.16E-04	181956	1902	BCL2 associated X, apoptosis regulator	gene	biological_process-&-1&-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0045136-&&-development of secondary sexual characteristics-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0060068-&&-vagina development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0032976-&&-release of matrix enzymes from mitochondria-%%-GO:0034644-&&-cellular response to UV-%%-GO:0070242-&&-thymocyte apoptotic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0016032-&&-viral process-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0021854-&&-hypothalamus development-%%-GO:0006808-&&-regulation of nitrogen utilization-%%-GO:0006915-&&-apoptotic process-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:1902445-&&-regulation of mitochondrial membrane permeability involved in programmed necrotic cell death-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0048515-&&-spermatid differentiation-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0001777-&&-T cell homeostatic proliferation-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0033599-&&-regulation of mammary gland epithelial cell proliferation-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048597-&&-post-embryonic camera-type eye morphogenesis-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0002904-&&-positive regulation of B cell apoptotic process-%%-GO:0009651-&&-response to salt stress-%%-GO:0048678-&&-response to axon injury-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:1902512-&&-positive regulation of apoptotic DNA fragmentation-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0001764-&&-neuron migration-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1902263-&&-apoptotic process involved in embryonic digit morphogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0046666-&&-retinal cell programmed cell death-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0007281-&&-germ cell development-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0060011-&&-Sertoli cell proliferation-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0009566-&&-fertilization-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:1902262-&&-apoptotic process involved in blood vessel morphogenesis-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:1990117-&&-B cell receptor apoptotic signaling pathway-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0048087-&&-positive regulation of developmental pigmentation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0060058-&&-positive regulation of apoptotic process involved in mammary gland involution-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0002352-&&-B cell negative selection-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0001822-&&-kidney development-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0002358-&&-B cell homeostatic proliferation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0032091-&&-negative regulation of protein binding|cellular_component-&-1&-GO:0005757-&&-mitochondrial permeability transition pore complex-%%-GO:0071944-&&-cell periphery-%%-GO:0005829-&&-cytosol-%%-GO:0097136-&&-Bcl-2 family protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0097144-&&-BAX complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008289-&&-lipid binding-%%-GO:0015267-&&-channel activity-%%-GO:0051434-&&-BH3 domain binding	G:9606:BAX	BAX	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05020-&&-Prion diseases-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa04217-&&-Necroptosis-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	BAX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAX	0.47880597	0.4129473	0.07628004	90	4	0.007978142	FALSE	9.06122449	BAX	BAX	107.5681818	9.709773275	0	89	0	0.76306391	FALSE	1	BAX	661428	Infinity	0.02978545
788372	taxon:9606	2.3666299	1011.156489	3.30E-04	177784	1902	tripartite motif containing 21	gene	biological_process-&-1&-GO:0070206-&&-protein trimerization-%%-GO:0031648-&&-protein destabilization-%%-GO:0045087-&&-innate immune response-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0090086-&&-negative regulation of protein deubiquitination-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0046598-&&-positive regulation of viral entry into host cell-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0007049-&&-cell cycle-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0010508-&&-positive regulation of autophagy|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005776-&&-autophagosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM21			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus	TRIM21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM21	0.499066584	0.42254177	0.08803553	90	4	0.015429107	FALSE	10.94117647	TRIM21	TRIM21	181.6477273	11.95690428	0	89	0	0.77222835	FALSE	1	TRIM21	576204	Infinity	0.04600732
788536	taxon:9606	2.51142272	300.8958588	0.00242263	177487	1902	secreted phosphoprotein 1	gene	biological_process-&-1&-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0031214-&&-biomineral tissue development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0046697-&&-decidualization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0007566-&&-embryo implantation-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0033280-&&-response to vitamin D-%%-GO:0007155-&&-cell adhesion-%%-GO:0048685-&&-negative regulation of collateral sprouting of intact axon in response to injury|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0005125-&&-cytokine activity	G:9606:SPP1	SPP1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	SPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPP1	0.453748232	0.39818068	0.01797753	90	4	0.005846475	FALSE	3.333333333	SPP1	SPP1	71.26666667	3.4375	0	90	0	0.74809621	FALSE	0	SPP1	3142726	Infinity	0.02367473
788950	taxon:9606	2.35402552	802.6312325	2.86E-04	176547	1902	ribonucleic acid export 1	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0001650-&&-fibrillar center-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003723-&&-RNA binding	G:9606:RAE1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A	RAE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAE1	0.495367511	0.42480423	0.08714107	90	4	0.012829635	FALSE	9.435483871	RAE1	RAE1	148.6444444	10.22253087	0	90	0	0.77432908	FALSE	0	RAE1	436516	Infinity	0.03685791
789034	taxon:9606	2.42004096	449.8153757	3.78E-04	176319	1902	transformation/transcription domain associated protein	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016573-&&-histone acetylation-%%-GO:0016578-&&-histone deubiquitination-%%-GO:0016310-&&-phosphorylation-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0000125-&&-PCAF complex-%%-GO:0000812-&&-Swr1 complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0003712-&&-transcription cofactor activity	G:9606:TRRAP			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	TRRAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRRAP	0.484885127	0.41321615	0.13657928	90	4	0.010003339	FALSE	10.20833333	TRRAP	TRRAP	131.7888889	11.01597098	0	90	0	0.76332651	FALSE	0	TRRAP	521954	Infinity	0.03616295
789389	taxon:9606	2.33354341	859.4384333	2.91E-04	175593	1902	PDZ and LIM domain 7	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007411-&&-axon guidance-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0001503-&&-ossification|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0001725-&&-stress fiber-%%-GO:0001726-&&-ruffle-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PDLIM7				PDLIM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDLIM7	0.49751861	0.42853285	0.10636704	90	4	0.011375352	FALSE	10.36923077	PDLIM7	PDLIM7	149.6111111	11.41842912	0	90	0	0.77774277	FALSE	0	PDLIM7	512728	Infinity	0.03599947
789672	taxon:9606	2.31400662	499.5394439	6.11E-04	174920	1902	HCLS1 associated protein X-1	gene	biological_process-&-1&-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0007005-&&-mitochondrion organization-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030854-&&-positive regulation of granulocyte differentiation|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005886-&&-plasma membrane-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005667-&&-transcription factor complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000932-&&-P-body-%%-GO:0030027-&&-lamellipodium-%%-GO:0005739-&&-mitochondrion-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:HAX1				HAX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAX1	0.492628993	0.43215088	0.05593009	90	4	0.010027833	FALSE	7.729166667	HAX1	HAX1	140.7555556	8.005545024	0	90	0	0.7809989	FALSE	0	HAX1	728052	Infinity	0.03290698
790292	taxon:9606	2.51095006	515.5019055	2.50E-04	173411	1902	bromodomain containing 4	gene	biological_process-&-1&-GO:1901407-&&-regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:BRD4				BRD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD4	0.465872785	0.39825563	0.17503121	90	4	0.015633132	FALSE	18.98360656	BRD4	BRD4	161.1666667	19.77938693	0	90	0	0.74817499	FALSE	0	BRD4	436514	Infinity	0.05283335
790574	taxon:9606	2.34488735	570.5192968	1.12E-04	172095	1902	proline, glutamate and leucine rich protein 1	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PELP1				PELP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PELP1	0.497672975	0.42645972	0.22139939	89	4	0.023762587	FALSE	20.94936709	PELP1	PELP1	246.5730337	21.53796476	0	89	0	0.77585211	FALSE	0	PELP1	346416	Infinity	0.06027207
791661	taxon:9606	2.41862297	666.6825479	3.88E-04	167558	1902	microtubule associated protein 1 light chain 3 beta	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0000422-&&-mitophagy-%%-GO:0016236-&&-macroautophagy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0012505-&&-endomembrane system-%%-GO:0005622-&&-intracellular-%%-GO:0005776-&&-autophagosome-%%-GO:0031090-&&-organelle membrane-%%-GO:0005930-&&-axoneme-%%-GO:0005739-&&-mitochondrion-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:MAP1LC3B			KEGG-&-1&-hsa04216-&&-Ferroptosis	MAP1LC3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1LC3B	0.483569491	0.41345841	0.06690501	89	4	0.007462616	FALSE	6.923076923	MAP1LC3B	MAP1LC3B	104.2696629	7.685702518	0	89	0	0.76356284	FALSE	0	MAP1LC3B	468374	Infinity	0.02863964
787903	taxon:9606	2.4592721	504.5644268	7.12E-05	178636	1902	proteasome 26S subunit, non-ATPase 12	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0005737-&&-cytoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex	G:9606:PSMD12			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD12	0.487537994	0.40662438	0.35578722	89	4	0.013076012	FALSE	33.48684211	PSMD12	PSMD12	148.6781609	36.61838738	0	88	0	0.75678798	FALSE	1	PSMD12	188974	Infinity	0.04406244
787906	taxon:9606	2.40712147	440.0410694	1.32E-04	178635	1902	proteasome 26S subunit, non-ATPase 13	gene	biological_process-&-1&-GO:0007127-&&-meiosis I-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043248-&&-proteasome assembly-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:PSMD13			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD13	0.494298921	0.41543396	0.33120531	89	4	0.013474499	FALSE	30.96	PSMD13	PSMD13	157.9775281	33.53514922	0	89	0	0.76547975	FALSE	0	PSMD13	269310	Infinity	0.04283251
788111	taxon:9606	2.43264534	412.7269905	3.94E-04	178216	1902	protein tyrosine phosphatase, non-receptor type 6	gene	biological_process-&-1&-GO:0002924-&&-negative regulation of humoral immune response mediated by circulating immunoglobulin-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070527-&&-platelet aggregation-%%-GO:0050859-&&-negative regulation of B cell receptor signaling pathway-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0030154-&&-cell differentiation-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0045577-&&-regulation of B cell differentiation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0033277-&&-abortive mitotic cell cycle-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030220-&&-platelet formation-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0008283-&&-cell proliferation-%%-GO:0043407-&&-negative regulation of MAP kinase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0042105-&&-alpha-beta T cell receptor complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:PTPN6			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa04520-&&-Adherens junction-%%-hsa04660-&&-T cell receptor signaling pathway	PTPN6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN6	0.47010551	0.41107513	0.15022721	89	4	0.006751825	FALSE	15.54716981	PTPN6	PTPN6	113.8275862	16.67446346	0	88	0	0.76122578	FALSE	1	PTPN6	479648	Infinity	0.03222101
792532	taxon:9606	2.34725067	417.192245	6.48E-04	181847	1902	calpain 1	gene	biological_process-&-1&-GO:0097264-&&-self proteolysis-%%-GO:0006508-&&-proteolysis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0060056-&&-mammary gland involution-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity	G:9606:CAPN1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CAPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPN1	0.490369917	0.42603034	0.06843718	89	4	0.010532722	FALSE	7.666666667	CAPN1	CAPN1	137.4719101	7.960425347	0	89	0	0.77545822	FALSE	0	CAPN1	733948	Infinity	0.03384908
788862	taxon:9606	2.40554593	444.5577346	2.66E-04	176737	1902	vitamin D (1,25- dihydroxyvitamin D3) receptor	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050892-&&-intestinal absorption-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0038183-&&-bile acid signaling pathway-%%-GO:0007595-&&-lactation-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0046697-&&-decidualization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060058-&&-positive regulation of apoptotic process involved in mammary gland involution-%%-GO:0006816-&&-calcium ion transport-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0060558-&&-regulation of calcidiol 1-monooxygenase activity-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0001501-&&-skeletal system development-%%-GO:0070561-&&-vitamin D receptor signaling pathway-%%-GO:0010980-&&-positive regulation of vitamin D 24-hydroxylase activity-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060745-&&-mammary gland branching involved in pregnancy|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008434-&&-calcitriol receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0070644-&&-vitamin D response element binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:1902098-&&-calcitriol binding-%%-GO:0038186-&&-lithocholic acid receptor activity-%%-GO:0003677-&&-DNA binding-%%-GO:1902121-&&-lithocholic acid binding	G:9606:VDR	VDR	TRUE	KEGG-&-1&-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05152-&&-Tuberculosis-%%-hsa04978-&&-Mineral absorption	VDR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDR	0.476530006	0.41570605	0.13124833	89	4	0.00843578	FALSE	15.14814815	VDR	VDR	130.7701149	15.97174646	0	88	0	0.76574235	FALSE	1	VDR	426056	Infinity	0.03515035
789324	taxon:9606	2.37687096	437.7810901	2.93E-04	175732	1902	receptor interacting serine/threonine kinase 1	gene	biological_process-&-1&-GO:0097527-&&-necroptotic signaling pathway-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:1901026-&&-ripoptosome assembly involved in necroptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0070231-&&-T cell apoptotic process-%%-GO:0070926-&&-regulation of ATP:ADP antiporter activity-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0070266-&&-necroptotic process-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0010940-&&-positive regulation of necrotic cell death-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0060545-&&-positive regulation of necroptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1905206-&&-positive regulation of hydrogen peroxide-induced cell death-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0097343-&&-ripoptosome assembly-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0071550-&&-death-inducing signaling complex assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0045121-&&-membrane raft-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0097342-&&-ripoptosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0070513-&&-death domain binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004871-&&-signal transducer activity	G:9606:RIPK1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa05163-&&-Human cytomegalovirus infection	RIPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK1	0.481971154	0.4207212	0.17348303	89	4	0.010085302	FALSE	18.95081967	RIPK1	RIPK1	134.862069	20.51765037	0	88	0	0.77052151	FALSE	1	RIPK1	429088	Infinity	0.03468083
789499	taxon:9606	2.51709469	499.2214258	1.99E-04	175332	1902	centrosomal protein 135	gene	biological_process-&-1&-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:CEP135				CEP135	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP135	0.457110288	0.39728343	0.1195097	89	4	0.00464887	FALSE	10.25	CEP135	CEP135	85.17977528	10.98420588	0	89	0	0.74715088	FALSE	0	CEP135	284394	Infinity	0.02813819
789636	taxon:9606	2.38427604	523.7992875	3.93E-04	175011	1902	TRK-fused gene	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TFG			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	TFG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFG	0.485178463	0.41941452	0.08233093	89	4	0.012218725	FALSE	10.6875	TFG	TFG	149.7126437	11.15828296	0	88	0	0.76928733	FALSE	1	TFG	545342	Infinity	0.03904626
790400	taxon:9606	2.45942965	821.4128259	2.37E-04	173116	1902	tripartite motif containing 29	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM29				TRIM29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM29	0.481971154	0.40659833	0.05506549	89	4	0.014699738	FALSE	7.588235294	TRIM29	TRIM29	147.8735632	8.187392236	0	88	0	0.75676172	FALSE	1	TRIM29	411294	Infinity	0.04377693
790768	taxon:9606	2.61131243	981.1016576	1.25E-04	171280	1902	leucine zipper protein 4	gene	biological_process-&-1&-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:LUZP4				LUZP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUZP4	0.45349166	0.3829492	0.09028728	88	4	0.014526199	FALSE	10.52307692	LUZP4	LUZP4	121.8255814	11.60322331	0	87	0	0.73144793	FALSE	1	LUZP4	254402	Infinity	0.04937381
791214	taxon:9606	2.53710414	597.8133711	2.13E-04	169718	1902	centromere protein J	gene	biological_process-&-1&-GO:0046785-&&-microtubule polymerization-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0046599-&&-regulation of centriole replication-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0061511-&&-centriole elongation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051301-&&-cell division-%%-GO:0044458-&&-motile cilium assembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule-%%-GO:0008275-&&-gamma-tubulin small complex-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CENPJ				CENPJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPJ	0.457501426	0.39415016	0.07497388	88	4	0.005423388	FALSE	6.787234043	CENPJ	CENPJ	84.60227273	7.112221361	0	88	0	0.74381598	FALSE	0	CENPJ	283216	Infinity	0.02931432
787233	taxon:9606	2.3746652	783.56172	1.46E-04	179821	1902	eukaryotic translation initiation factor 3 subunit E	gene	biological_process-&-1&-GO:0045947-&&-negative regulation of translational initiation-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006413-&&-translational initiation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0000785-&&-chromatin-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016604-&&-nuclear body-%%-GO:0016605-&&-PML body-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0003723-&&-RNA binding	G:9606:EIF3E			KEGG-&-1&-hsa05160-&&-Hepatitis C-%%-hsa03013-&&-RNA transport	EIF3E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3E	0.49644073	0.421112	0.17868339	88	4	0.018492637	FALSE	17.02816901	EIF3E	EIF3E	177.4659091	18.34242495	0	88	0	0.77088913	FALSE	0	EIF3E	327074	Infinity	0.0455216
787407	taxon:9606	2.45596345	584.1269587	1.24E-04	179482	1902	nibrin	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0090656-&&-t-circle formation-%%-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0001832-&&-blastocyst growth-%%-GO:0030174-&&-regulation of DNA-dependent DNA replication initiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000732-&&-strand displacement-%%-GO:0008283-&&-cell proliferation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0000723-&&-telomere maintenance-%%-GO:0045190-&&-isotype switching-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0031860-&&-telomeric 3' overhang formation|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0016605-&&-PML body-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0030870-&&-Mre11 complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:NBN			KEGG-&-1&-hsa03440-&&-Homologous recombination-%%-hsa04218-&&-Cellular senescence	NBN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBN	0.486650485	0.40717218	0.17763845	88	4	0.015279827	FALSE	16.9	NBN	NBN	172.875	18.24158193	0	88	0	0.75733943	FALSE	0	NBN	302030	Infinity	0.05079742
787456	taxon:9606	2.35181976	765.2742705	4.25E-04	179403	1902	mitogen-activated protein kinase kinase kinase 5	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0007254-&&-JNK cascade-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042060-&&-wound healing-%%-GO:0016032-&&-viral process-%%-GO:1902170-&&-cellular response to reactive nitrogen species-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0002931-&&-response to ischemia-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:1902911-&&-protein kinase complex-%%-GO:1990604-&&-IRE1-TRAF2-ASK1 complex-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:MAP3K5			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04530-&&-Tight junction-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	MAP3K5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K5	0.490519878	0.42520265	0.09931601	88	4	0.010988419	FALSE	11.796875	MAP3K5	MAP3K5	149.2790698	12.885669	0	87	0	0.77469671	FALSE	1	MAP3K5	611718	Infinity	0.03689309
787870	taxon:9606	2.38270049	413.4383697	1.06E-04	178668	1902	proteasome subunit alpha 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0000932-&&-P-body-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA4			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA4	0.495367511	0.41969186	0.34117647	88	4	0.013548082	FALSE	32.45945946	PSMA4	PSMA4	162.9534884	34.78184142	0	87	0	0.76954992	FALSE	1	PSMA4	248960	Infinity	0.04222084
787878	taxon:9606	2.38207027	390.5505778	1.68E-04	178661	1902	proteasome subunit beta 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0002862-&&-negative regulation of inflammatory response to antigenic stimulus-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB4	PSMB4	TRUE	KEGG-&-1&-hsa03050-&&-Proteasome	PSMB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB4	0.492628993	0.4198029	0.31922675	88	4	0.011753014	FALSE	29.61971831	PSMB4	PSMB4	146.3636364	31.73339358	0	88	0	0.76965496	FALSE	0	PSMB4	318002	Infinity	0.03792492
792072	taxon:9606	2.25618402	535.1573843	0.00141875	182663	1902	clusterin	gene	biological_process-&-1&-GO:1902847-&&-regulation of neuronal signal transduction-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1903573-&&-negative regulation of response to endoplasmic reticulum stress-%%-GO:0017038-&&-protein import-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0006956-&&-complement activation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0050821-&&-protein stabilization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:1900221-&&-regulation of beta-amyloid clearance-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0051788-&&-response to misfolded protein-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:1905895-&&-negative regulation of cellular response to tunicamycin-%%-GO:0001774-&&-microglial cell activation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0032286-&&-central nervous system myelin maintenance-%%-GO:0061518-&&-microglial cell proliferation-%%-GO:1905907-&&-negative regulation of amyloid fibril formation-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:1902949-&&-positive regulation of tau-protein kinase activity-%%-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:1905892-&&-negative regulation of cellular response to thapsigargin-%%-GO:1902998-&&-positive regulation of neurofibrillary tangle assembly-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:1902430-&&-negative regulation of beta-amyloid formation-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0009615-&&-response to virus-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0042583-&&-chromaffin granule-%%-GO:0071944-&&-cell periphery-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0097440-&&-apical dendrite-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0034366-&&-spherical high-density lipoprotein particle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009986-&&-cell surface-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CLU			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	CLU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLU	0.497210167	0.44322626	0.06073871	88	4	0.010388087	FALSE	9.490196078	CLU	CLU	152.9534884	10.04364482	0	87	0	0.790636	FALSE	1	CLU	1370184	Infinity	0.03300266
787968	taxon:9606	2.3199937	418.2184182	1.92E-04	178491	1902	poly(rC) binding protein 2	gene	biological_process-&-1&-GO:0016071-&&-mRNA metabolic process-%%-GO:0045087-&&-innate immune response-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0051607-&&-defense response to virus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:1990829-&&-C-rich single-stranded DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PCBP2			KEGG-&-1&-hsa04216-&&-Ferroptosis	PCBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBP2	0.500780518	0.43103565	0.20273598	88	4	0.022936523	FALSE	21.16901408	PCBP2	PCBP2	234.2906977	22.01601872	0	87	0	0.78000105	FALSE	1	PCBP2	375982	Infinity	0.05517916
788072	taxon:9606	2.45296991	215.1443308	2.48E-05	178281	1902	ribosomal protein L32	gene	biological_process-&-1&-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0097421-&&-liver regeneration-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL32			KEGG-&-1&-hsa03010-&&-Ribosome	RPL32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL32	0.486945962	0.40766909	0.53683386	88	4	0.032561012	FALSE	47.4137931	RPL32	RPL32	234.8409091	48.73792557	0	88	0	0.75783835	FALSE	0	RPL32	127570	Infinity	0.06840691
792164	taxon:9606	2.41326611	557.1870848	5.72E-04	182492	1902	Fas cell surface death receptor	gene	biological_process-&-1&-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0003014-&&-renal system process-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0097049-&&-motor neuron apoptotic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045619-&&-regulation of lymphocyte differentiation-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0048536-&&-spleen development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006915-&&-apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007165-&&-signal transduction-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0006925-&&-inflammatory cell apoptotic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0019724-&&-B cell mediated immunity-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0050869-&&-negative regulation of B cell activation-%%-GO:0070230-&&-positive regulation of lymphocyte apoptotic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0045637-&&-regulation of myeloid cell differentiation-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016604-&&-nuclear body-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0009986-&&-cell surface-%%-GO:0031264-&&-death-inducing signaling complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0043120-&&-tumor necrosis factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:FAS	FAS	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05330-&&-Allograft rejection-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	FAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAS	0.470519214	0.41437618	0.07770178	88	4	0.006553622	FALSE	10.41509434	FAS	FAS	108.372093	11.0737416	0	87	0	0.76445565	FALSE	1	FAS	705286	Infinity	0.02965913
792255	taxon:9606	2.36064282	635.176828	2.45E-04	182340	1902	ATR serine/threonine kinase	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006260-&&-DNA replication-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0090399-&&-replicative senescence-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:1904884-&&-positive regulation of telomerase catalytic core complex assembly-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0034644-&&-cellular response to UV-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006281-&&-DNA repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0007049-&&-cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0097694-&&-establishment of RNA localization to telomere-%%-GO:0097695-&&-establishment of macromolecular complex localization to telomere|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005694-&&-chromosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0032407-&&-MutSalpha complex binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0005524-&&-ATP binding	G:9606:ATR	ATR	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa05165-&&-Human papillomavirus infection	ATR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATR	0.490070272	0.42361343	0.11627907	88	4	0.01124576	FALSE	12.56140351	ATR	ATR	149.3139535	13.36650615	0	87	0	0.7732262	FALSE	1	ATR	434240	Infinity	0.0372947
792272	taxon:9606	2.36206082	546.9605226	2.39E-04	182308	1902	cell division cycle 27	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007091-&&-metaphase/anaphase transition of mitotic cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:CDC27	CDC27	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC27	0.49247774	0.42335912	0.13296854	88	4	0.009671211	FALSE	11.43636364	CDC27	CDC27	146.6162791	12.15146372	0	87	0	0.77298986	FALSE	1	CDC27	428840	Infinity	0.03670622
792307	taxon:9606	2.52654798	218.6136296	1.18E-04	182251	1902	centromere protein A	gene	biological_process-&-1&-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0071459-&&-protein localization to chromosome, centromeric region-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0016032-&&-viral process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051382-&&-kinetochore assembly|cellular_component-&-1&-GO:0000778-&&-condensed nuclear chromosome kinetochore-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0000939-&&-condensed chromosome inner kinetochore-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:CENPA				CENPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPA	0.474696656	0.39579696	0.27140903	88	4	0.021385942	FALSE	28.82191781	CENPA	CENPA	192.1046512	29.74977134	0	87	0	0.74557534	FALSE	1	CENPA	246598	Infinity	0.06464427
788375	taxon:9606	2.27887191	595.9939796	2.42E-04	177781	1902	Sjogren syndrome antigen B	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0075522-&&-IRES-dependent viral translational initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SSB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus	SSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSB	0.503136763	0.43881361	0.13351573	88	4	0.020274848	FALSE	15.04285714	SSB	SSB	234.1395349	15.7140757	0	87	0	0.78685468	FALSE	1	SSB	501928	Infinity	0.05197705
788390	taxon:9606	2.36726012	558.2873266	6.25E-04	177749	1902	signal transducer and activator of transcription 5A	gene	biological_process-&-1&-GO:0006573-&&-valine metabolic process-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0007595-&&-lactation-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0006101-&&-citrate metabolic process-%%-GO:0006549-&&-isoleucine metabolic process-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000255-&&-allantoin metabolic process-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0038161-&&-prolactin signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:STAT5A			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis	STAT5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT5A	0.481392557	0.42242928	0.11709986	88	4	0.008198496	FALSE	13.77777778	STAT5A	STAT5A	129.7325581	14.58547729	0	87	0	0.77212331	FALSE	1	STAT5A	733804	Infinity	0.03292015
792507	taxon:9606	2.47061604	708.0641898	2.67E-04	165507	1902	HAUS augmin like complex subunit 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:HAUS1				HAUS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS1	0.471071953	0.40475735	0.09603283	88	4	0.007988688	FALSE	9.596153846	HAUS1	HAUS1	112.4651163	10.55099745	0	87	0	0.75489733	FALSE	1	HAUS1	396168	Infinity	0.03391911
793235	taxon:9606	2.49346148	478.4238339	2.35E-04	164096	1902	spindle and centriole associated protein 1	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0046599-&&-regulation of centriole replication-%%-GO:0051301-&&-cell division-%%-GO:0051310-&&-metaphase plate congression|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005819-&&-spindle-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPICE1				SPICE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPICE1	0.464389114	0.40104891	0.09090909	88	4	0.005785503	FALSE	8.022222222	SPICE1	SPICE1	90.42045455	8.269933916	0	88	0	0.75108975	FALSE	0	SPICE1	312940	Infinity	0.02843414
793304	taxon:9606	2.3565464	612.7955414	3.07E-04	180346	1902	host cell factor C1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050821-&&-protein stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0019046-&&-release from viral latency-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0007049-&&-cell cycle-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0070461-&&-SAGA-type complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0071339-&&-MLL1 complex-%%-GO:0016020-&&-membrane-%%-GO:0000123-&&-histone acetyltransferase complex|molecular_function-&-1&-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:HCFC1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	HCFC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HCFC1	0.492780338	0.4243498	0.10369357	88	4	0.012260148	FALSE	11.36363636	HCFC1	HCFC1	162.9069767	12.33715694	0	87	0	0.77390893	FALSE	1	HCFC1	517648	Infinity	0.04042206
789535	taxon:9606	2.38049472	835.3091432	1.36E-04	175237	1902	DDB1 and CUL4 associated factor 1	gene	biological_process-&-1&-GO:1990245-&&-histone H2A-T120 phosphorylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035212-&&-cell competition in a multicellular organism-%%-GO:0016032-&&-viral process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030183-&&-B cell differentiation-%%-GO:0033151-&&-V(D)J recombination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:1990244-&&-histone kinase activity (H2A-T120 specific)-%%-GO:0005524-&&-ATP binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding	G:9606:DCAF1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection	DCAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCAF1	0.494146642	0.42008075	0.1625171	88	4	0.018638888	FALSE	16.74647887	DCAF1	DCAF1	205.5697674	18.14293692	0	87	0	0.76991755	FALSE	1	DCAF1	375290	Infinity	0.05293498
789673	taxon:9606	2.58200725	709.1687788	2.50E-04	174923	1902	translocase of outer mitochondrial membrane 40	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0030150-&&-protein import into mitochondrial matrix-%%-GO:0006626-&&-protein targeting to mitochondrion|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005742-&&-mitochondrial outer membrane translocase complex-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0046930-&&-pore complex|molecular_function-&-1&-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0015266-&&-protein channel activity-%%-GO:0015288-&&-porin activity	G:9606:TOMM40			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	TOMM40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOMM40	0.445803224	0.38729558	0.07001045	88	4	0.005288042	FALSE	5.468085106	TOMM40	TOMM40	76.67045455	6.21086397	0	88	0	0.73633213	FALSE	0	TOMM40	300644	Infinity	0.02937385
789694	taxon:9606	2.34662045	492.469216	1.79E-04	174879	1902	coactivator associated arginine methyltransferase 1	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0003420-&&-regulation of growth plate cartilage chondrocyte proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0034970-&&-histone H3-R2 methylation-%%-GO:0034971-&&-histone H3-R17 methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000171-&&-negative regulation of dendrite development-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0007568-&&-aging-%%-GO:0016571-&&-histone methylation-%%-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0051591-&&-response to cAMP-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0060350-&&-endochondral bone morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:1902415-&&-regulation of mRNA binding-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0045600-&&-positive regulation of fat cell differentiation|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0035642-&&-histone methyltransferase activity (H3-R17 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008276-&&-protein methyltransferase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CARM1			KEGG-&-1&-hsa01522-&&-Endocrine resistance	CARM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARM1	0.498756219	0.42614476	0.1700627	88	4	0.01882978	FALSE	17.30434783	CARM1	CARM1	212.8863636	17.92633622	0	88	0	0.77556326	FALSE	0	CARM1	410146	Infinity	0.05215411
790489	taxon:9606	2.35418308	559.2025745	9.93E-05	172715	1902	NOC2 like nucleolar associated transcriptional repressor	gene	biological_process-&-1&-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034644-&&-cellular response to UV-%%-GO:0031497-&&-chromatin assembly-%%-GO:0032066-&&-nucleolus to nucleoplasm transport|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0030690-&&-Noc1p-Noc2p complex-%%-GO:0030691-&&-Noc2p-Noc3p complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:NOC2L				NOC2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOC2L	0.494908979	0.4247758	0.23772205	88	4	0.022489132	FALSE	20.125	NOC2L	NOC2L	239.0227273	20.98414314	0	88	0	0.77430282	FALSE	0	NOC2L	318590	Infinity	0.05907069
787073	taxon:9606	2.23176304	519.7874055	9.16E-04	180119	1902	insulin like growth factor 1 receptor	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006955-&&-immune response-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0051389-&&-inactivation of MAPKK activity-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0051262-&&-protein tetramerization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0035867-&&-alphav-beta3 integrin-IGF-1-IGF1R complex-%%-GO:0043235-&&-receptor complex-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0005010-&&-insulin-like growth factor-activated receptor activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0043559-&&-insulin binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005520-&&-insulin-like growth factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:IGF1R	IGF1R	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa01522-&&-Endocrine resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma	IGF1R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF1R	0.497364341	0.44807624	0.14453782	87	4	0.011610239	FALSE	17.96296296	IGF1R	IGF1R	184.7058824	18.96378881	0	86	0	0.79470616	FALSE	1	IGF1R	1010106	Infinity	0.03851561
787659	taxon:9606	2.32298724	826.562955	1.97E-04	179000	1902	nuclear mitotic apparatus protein 1	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0051301-&&-cell division-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0061673-&&-mitotic spindle astral microtubule-%%-GO:0097431-&&-mitotic spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0030425-&&-dendrite-%%-GO:0005813-&&-centrosome-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:NUMA1				NUMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUMA1	0.502348888	0.4304802	0.12777332	87	4	0.018487701	FALSE	12.53521127	NUMA1	NUMA1	213.954023	13.17087373	0	87	0	0.77950213	FALSE	0	NUMA1	417516	Infinity	0.05053887
791826	taxon:9606	2.52843863	385.5273514	2.04E-04	166668	1902	polycomb group ring finger 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PCGF1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	PCGF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCGF1	0.464523603	0.395501	0.14705882	87	4	0.011776997	FALSE	13.74545455	PCGF1	PCGF1	146.6352941	14.56005492	0	86	0	0.74526023	FALSE	1	PCGF1	402700	Infinity	0.04942207
787763	taxon:9606	2.38490625	450.6624686	2.66E-04	178826	1902	mediator complex subunit 1	gene	biological_process-&-1&-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2001141-&&-regulation of RNA biosynthetic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0007595-&&-lactation-%%-GO:0006590-&&-thyroid hormone generation-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0001889-&&-liver development-%%-GO:0006702-&&-androgen biosynthetic process-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:0060745-&&-mammary gland branching involved in pregnancy-%%-GO:0003406-&&-retinal pigment epithelium development-%%-GO:0007420-&&-brain development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0048821-&&-erythrocyte development-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0070318-&&-positive regulation of G0 to G1 transition-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0060750-&&-epithelial cell proliferation involved in mammary gland duct elongation-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0060335-&&-positive regulation of interferon-gamma-mediated signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:0002154-&&-thyroid hormone mediated signaling pathway-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0070562-&&-regulation of vitamin D receptor signaling pathway-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048822-&&-enucleate erythrocyte development-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0045665-&&-negative regulation of neuron differentiation|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0000785-&&-chromatin-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0050693-&&-LBD domain binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004872-&&-receptor activity-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0036033-&&-mediator complex binding	G:9606:MED1			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance	MED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED1	0.486945962	0.41930369	0.20756303	87	4	0.008844986	FALSE	15.01886792	MED1	MED1	138.3882353	16.91449975	0	86	0	0.76918229	FALSE	1	MED1	425246	Infinity	0.03586741
787881	taxon:9606	2.3948322	355.0975326	1.06E-04	178662	1902	proteasome subunit beta 3	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0019774-&&-proteasome core complex, beta-subunit complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB3			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB3	0.493690366	0.41756579	0.34985994	87	4	0.012784126	FALSE	32.32876712	PSMB3	PSMB3	161.1882353	34.82137141	0	86	0	0.76752797	FALSE	1	PSMB3	267436	Infinity	0.04253489
792061	taxon:9606	2.35402552	530.1352679	3.82E-04	182672	1902	Bruton tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0098761-&&-cellular response to interleukin-7-%%-GO:0007498-&&-mesoderm development-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0001812-&&-positive regulation of type I hypersensitivity-%%-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042113-&&-B cell activation-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0002553-&&-histamine secretion by mast cell-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002902-&&-regulation of B cell apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048469-&&-cell maturation-%%-GO:0001805-&&-positive regulation of type III hypersensitivity-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0071226-&&-cellular response to molecule of fungal origin-%%-GO:0002344-&&-B cell affinity maturation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0002721-&&-regulation of B cell cytokine production|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042629-&&-mast cell granule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity	G:9606:BTK			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05340-&&-Primary immunodeficiency	BTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTK	0.48371532	0.42480423	0.11036415	87	4	0.009461788	FALSE	11.57894737	BTK	BTK	135.8235294	12.42422587	0	86	0	0.77432908	FALSE	1	BTK	502828	Infinity	0.03371945
792069	taxon:9606	2.40822436	1087.625891	3.12E-04	182666	1902	bystin like	gene	biological_process-&-1&-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0007565-&&-female pregnancy-%%-GO:0008283-&&-cell proliferation-%%-GO:0007155-&&-cell adhesion-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:BYSL				BYSL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BYSL	0.485325265	0.4152437	0.0837535	87	4	0.010760348	FALSE	9.321428571	BYSL	BYSL	132.8705882	10.56617701	0	86	0	0.76529594	FALSE	1	BYSL	484156	Infinity	0.03584316
788077	taxon:9606	2.55616827	169.9405145	3.27E-05	178278	1902	ribosomal protein L35a	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:RPL35A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL35A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL35A	0.467638484	0.39121055	0.57925688	87	4	0.028340857	FALSE	53.18518519	RPL35A	RPL35A	177.6206897	54.17119611	0	87	0	0.74063862	FALSE	0	RPL35A	86928	Infinity	0.06372773
788166	taxon:9606	2.40617615	383.5432854	3.82E-04	178137	1902	RAD51 recombinase	gene	biological_process-&-1&-GO:0000730-&&-DNA recombinase assembly-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0031297-&&-replication fork processing-%%-GO:0070192-&&-chromosome organization involved in meiotic cell cycle-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0072757-&&-cellular response to camptothecin-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0000732-&&-strand displacement-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:1904631-&&-response to glucoside-%%-GO:0042493-&&-response to drug-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1990426-&&-mitotic recombination-dependent replication fork processing-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0051106-&&-positive regulation of DNA ligation-%%-GO:0006312-&&-mitotic recombination-%%-GO:0042148-&&-strand invasion-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0072719-&&-cellular response to cisplatin-%%-GO:0006310-&&-DNA recombination-%%-GO:0009636-&&-response to toxic substance-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:1990414-&&-replication-born double-strand break repair via sister chromatid exchange-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0006281-&&-DNA repair-%%-GO:0010165-&&-response to X-ray|cellular_component-&-1&-GO:0000793-&&-condensed chromosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0016605-&&-PML body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005739-&&-mitochondrion-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0000150-&&-recombinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004520-&&-endodeoxyribonuclease activity	G:9606:RAD51			KEGG-&-1&-hsa05212-&&-Pancreatic cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway	RAD51	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD51	0.482841662	0.41559717	0.09103641	87	4	0.009185361	FALSE	11.33333333	RAD51	RAD51	126.4941177	11.67937298	0	86	0	0.76563731	FALSE	1	RAD51	466286	Infinity	0.03418064
788204	taxon:9606	2.35701906	516.287628	2.57E-04	178091	1902	RNA binding motif protein 4	gene	biological_process-&-1&-GO:0097167-&&-circadian regulation of translation-%%-GO:0006396-&&-RNA processing-%%-GO:0032055-&&-negative regulation of translation in response to stress-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0002190-&&-cap-independent translational initiation-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0008380-&&-RNA splicing-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0002192-&&-IRES-dependent translational initiation-%%-GO:0006397-&&-mRNA processing-%%-GO:0030154-&&-cell differentiation-%%-GO:0045947-&&-negative regulation of translational initiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0097158-&&-pre-mRNA intronic pyrimidine-rich binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0097157-&&-pre-mRNA intronic binding	G:9606:RBM4				RBM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM4	0.495061728	0.42426471	0.17401764	87	4	0.020214798	FALSE	19.16666667	RBM4	RBM4	214.3563218	19.83968615	0	87	0	0.77383016	FALSE	0	RBM4	463300	Infinity	0.05336413
792335	taxon:9606	2.27241216	298.2534515	4.36E-04	182208	1902	checkpoint kinase 1	gene	biological_process-&-1&-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0006260-&&-DNA replication-%%-GO:0035407-&&-histone H3-T11 phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0010767-&&-regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0006281-&&-DNA repair-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0045839-&&-negative regulation of mitotic nuclear division-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0046602-&&-regulation of mitotic centrosome separation-%%-GO:0007049-&&-cell cycle-%%-GO:0090399-&&-replicative senescence|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0000785-&&-chromatin-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000794-&&-condensed nuclear chromosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035402-&&-histone kinase activity (H3-T11 specific)-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CHEK1	CHEK1	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence	CHEK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHEK1	0.499532856	0.44006101	0.13124833	87	4	0.014527518	FALSE	13.62068966	CHEK1	CHEK1	187.9885058	14.01791975	0	87	0	0.78793131	FALSE	0	CHEK1	581314	Infinity	0.04133836
792583	taxon:9606	2.42744604	584.8389095	4.59E-04	181770	1902	CD4 molecule	gene	biological_process-&-1&-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061024-&&-membrane organization-%%-GO:0001816-&&-cytokine production-%%-GO:0006955-&&-immune response-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010524-&&-positive regulation of calcium ion transport into cytosol-%%-GO:0030260-&&-entry into host cell-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0032507-&&-maintenance of protein location in cell-%%-GO:0030217-&&-T cell differentiation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0035397-&&-helper T cell enhancement of adaptive immune response-%%-GO:0045058-&&-T cell selection-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0006948-&&-induction by virus of host cell-cell fusion-%%-GO:0033280-&&-response to vitamin D-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0019064-&&-fusion of virus membrane with host plasma membrane-%%-GO:0050863-&&-regulation of T cell activation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005769-&&-early endosome-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0042289-&&-MHC class II protein binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019865-&&-immunoglobulin binding-%%-GO:1990782-&&-protein tyrosine kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004872-&&-receptor activity-%%-GO:0015026-&&-coreceptor activity	G:9606:CD4	CD4	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04660-&&-T cell receptor signaling pathway	CD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD4	0.480239521	0.4119556	0.08235294	87	4	0.01386468	FALSE	10.75	CD4	CD4	127.7294118	11.60828191	0	86	0	0.76209233	FALSE	1	CD4	592322	Infinity	0.03587276
788656	taxon:9606	2.44698283	324.4513604	9.10E-04	177241	1902	transforming growth factor beta receptor 2	gene	biological_process-&-1&-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0002651-&&-positive regulation of tolerance induction to self antigen-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0007420-&&-brain development-%%-GO:0002663-&&-positive regulation of B cell tolerance induction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0043627-&&-response to estrogen-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007566-&&-embryo implantation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0009749-&&-response to glucose-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0042060-&&-wound healing-%%-GO:0003274-&&-endocardial cushion fusion-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0003186-&&-tricuspid valve morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1905315-&&-cell proliferation involved in endocardial cushion morphogenesis-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0001568-&&-blood vessel development-%%-GO:0007507-&&-heart development-%%-GO:0048565-&&-digestive tract development-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0003430-&&-growth plate cartilage chondrocyte growth-%%-GO:0001570-&&-vasculogenesis-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0060434-&&-bronchus morphogenesis-%%-GO:0007568-&&-aging-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007369-&&-gastrulation-%%-GO:0002666-&&-positive regulation of T cell tolerance induction-%%-GO:1990086-&&-lens fiber cell apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0060440-&&-trachea formation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0060463-&&-lung lobe morphogenesis-%%-GO:0060443-&&-mammary gland morphogenesis-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0051138-&&-positive regulation of NK T cell differentiation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043415-&&-positive regulation of skeletal muscle tissue regeneration-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0070723-&&-response to cholesterol-%%-GO:0060021-&&-palate development-%%-GO:0007584-&&-response to nutrient-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0003214-&&-cardiac left ventricle morphogenesis|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0005901-&&-caveola-%%-GO:0070022-&&-transforming growth factor beta receptor complex-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0005026-&&-transforming growth factor beta receptor activity, type II-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity	G:9606:TGFBR2			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TGFBR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBR2	0.46412037	0.40866654	0.0719888	87	4	0.005267489	FALSE	9.571428571	TGFBR2	TGFBR2	94.11764706	9.943767734	0	86	0	0.7588362	FALSE	1	TGFBR2	991830	Infinity	0.02736193
792800	taxon:9606	2.34961399	540.1853665	2.35E-04	181348	1902	eukaryotic translation initiation factor 4 gamma 1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0007005-&&-mitochondrion organization-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0002191-&&-cap-dependent translational initiation-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0006412-&&-translation-%%-GO:0034645-&&-cellular macromolecule biosynthetic process-%%-GO:0080135-&&-regulation of cellular response to stress-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001662-&&-behavioral fear response-%%-GO:0060964-&&-regulation of gene silencing by miRNA-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0016032-&&-viral process-%%-GO:0032502-&&-developmental process-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:1905537-&&-positive regulation of eukaryotic translation initiation factor 4F complex assembly-%%-GO:1905612-&&-positive regulation of mRNA cap binding-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:1905606-&&-regulation of presynapse assembly-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0006413-&&-translational initiation-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:1905696-&&-regulation of polysome binding-%%-GO:2000507-&&-positive regulation of energy homeostasis-%%-GO:1905618-&&-positive regulation of miRNA mediated inhibition of translation-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0008190-&&-eukaryotic initiation factor 4E binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0032947-&&-protein complex scaffold	G:9606:EIF4G1			KEGG-&-1&-hsa05416-&&-Viral myocarditis-%%-hsa03013-&&-RNA transport	EIF4G1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4G1	0.495520544	0.42560182	0.13766373	87	4	0.016113974	FALSE	13.19047619	EIF4G1	EIF4G1	186.9310345	13.94252283	0	87	0	0.77506433	FALSE	0	EIF4G1	393492	Infinity	0.04604497
788896	taxon:9606	2.36899323	795.8822864	3.65E-04	176653	1902	YES proto-oncogene 1, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0015758-&&-glucose transport-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0030154-&&-cell differentiation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005524-&&-ATP binding	G:9606:YES1			KEGG-&-1&-hsa04520-&&-Adherens junction	YES1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YES1	0.483861237	0.42212024	0.07310924	87	4	0.008897589	FALSE	9.5	YES1	YES1	131.8	10.64733924	0	86	0	0.77183446	FALSE	1	YES1	544028	Infinity	0.03350787
789207	taxon:9606	2.40223728	371.2935347	1.65E-04	176000	1902	Y-box binding protein 3	gene	biological_process-&-1&-GO:1902219-&&-negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress-%%-GO:0009409-&&-response to cold-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071474-&&-cellular hyperosmotic response-%%-GO:0046622-&&-positive regulation of organ growth-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0008584-&&-male gonad development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0009566-&&-fertilization-%%-GO:2000767-&&-positive regulation of cytoplasmic translation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:YBX3			KEGG-&-1&-hsa04530-&&-Tight junction	YBX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YBX3	0.489770992	0.41627861	0.15183106	87	4	0.022072058	FALSE	15.37313433	YBX3	YBX3	221.5057471	15.92228147	0	87	0	0.76629379	FALSE	0	YBX3	430958	Infinity	0.05910979
789619	taxon:9606	2.35922483	291.237512	1.05E-04	175046	1902	heterogeneous nuclear ribonucleoprotein D like	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPDL				HNRNPDL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPDL	0.495673671	0.42386804	0.28281208	87	4	0.0241496	FALSE	27.8630137	HNRNPDL	HNRNPDL	233.0229885	28.75697691	0	87	0	0.77346253	FALSE	0	HNRNPDL	253536	Infinity	0.0582966
790155	taxon:9606	2.42461005	408.1261915	1.98E-04	173751	1902	apoptotic chromatin condensation inducer 1	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0045657-&&-positive regulation of monocyte differentiation-%%-GO:0030263-&&-apoptotic chromosome condensation-%%-GO:0006397-&&-mRNA processing-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0030218-&&-erythrocyte differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0061574-&&-ASAP complex|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:ACIN1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	ACIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACIN1	0.489472078	0.41243746	0.2183908	87	4	0.020347876	FALSE	21.54166667	ACIN1	ACIN1	210.7126437	22.49117201	0	87	0	0.76256499	FALSE	0	ACIN1	366696	Infinity	0.05845357
790185	taxon:9606	2.3864818	356.0786037	2.31E-04	173696	1902	nuclear receptor coactivator 6	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0007420-&&-brain development-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0006310-&&-DNA recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006260-&&-DNA replication-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding	G:9606:NCOA6				NCOA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA6	0.488726386	0.41902687	0.17142857	87	4	0.01173355	FALSE	17.86885246	NCOA6	NCOA6	156.0470588	18.95796066	0	86	0	0.7689197	FALSE	1	NCOA6	397190	Infinity	0.04069778
787468	taxon:9606	2.39861352	307.4400016	3.65E-04	179377	1902	O-6-methylguanine-DNA methyltransferase	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0051593-&&-response to folic acid-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006306-&&-DNA methylation-%%-GO:0042493-&&-response to drug-%%-GO:0009636-&&-response to toxic substance-%%-GO:2000781-&&-positive regulation of double-strand break repair-%%-GO:0045471-&&-response to ethanol-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0006307-&&-DNA dealkylation involved in DNA repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:0003908-&&-methylated-DNA-[protein]-cysteine S-methyltransferase activity-%%-GO:0008168-&&-methyltransferase activity	G:9606:MGMT				MGMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGMT	0.49338665	0.41690751	0.11044177	86	4	0.017851641	FALSE	13.34848485	MGMT	MGMT	176.1547619	13.68271278	0	85	0	0.76689775	FALSE	1	MGMT	638026	Infinity	0.04688986
788148	taxon:9606	2.4926737	734.626855	2.38E-04	178162	1902	RAB2A, member RAS oncogene family	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0019003-&&-GDP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding	G:9606:RAB2A			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway	RAB2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB2A	0.470933647	0.40117565	0.09150889	86	4	0.008349031	FALSE	10.31034483	RAB2A	RAB2A	109.1071429	11.44922744	0	85	0	0.75122105	FALSE	1	RAB2A	335814	Infinity	0.03449406
792241	taxon:9606	2.29888136	731.4721114	2.94E-04	182367	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	gene	biological_process-&-1&-GO:0006754-&&-ATP biosynthetic process-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000275-&&-mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0003723-&&-RNA binding	G:9606:ATP5C1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5C1	0.493538462	0.43499417	0.17099863	86	4	0.013563465	FALSE	15.31578947	ATP5C1	ATP5C1	190.7790698	17.04620854	0	86	0	0.78351977	FALSE	0	ATP5C1	583576	Infinity	0.04355687
792289	taxon:9606	2.36347881	312.8935243	3.85E-04	182283	1902	cyclin dependent kinase 6	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0042063-&&-gliogenesis-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0051301-&&-cell division-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:1904628-&&-cellular response to phorbol 13-acetate 12-myristate-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0010468-&&-regulation of gene expression-%%-GO:2000145-&&-regulation of cell motility-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0003323-&&-type B pancreatic cell development-%%-GO:0009615-&&-response to virus-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0045646-&&-regulation of erythrocyte differentiation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0014002-&&-astrocyte development-%%-GO:0043697-&&-cell dedifferentiation-%%-GO:0048699-&&-generation of neurons-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045656-&&-negative regulation of monocyte differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0001726-&&-ruffle-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0098770-&&-FBXO family protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK6	CDK6	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa05214-&&-Glioma-%%-hsa05160-&&-Hepatitis C-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma	CDK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK6	0.486650485	0.42310513	0.08405049	86	4	0.008699941	FALSE	10.71111111	CDK6	CDK6	129.0714286	10.98961039	0	85	0	0.77275353	FALSE	1	CDK6	479484	Infinity	0.0323727
792518	taxon:9606	2.35197731	736.68373	3.35E-04	181857	1902	calumenin	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0033018-&&-sarcoplasmic reticulum lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:CALU				CALU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALU	0.491722869	0.42517417	0.09466484	86	4	0.010727604	FALSE	7.740740741	CALU	CALU	151.5930233	8.339839082	0	86	0	0.77467045	FALSE	0	CALU	539830	Infinity	0.03749935
792796	taxon:9606	2.35244998	793.7011537	1.26E-04	181353	1902	eukaryotic translation initiation factor 4B	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0001731-&&-formation of translation preinitiation complex-%%-GO:0097010-&&-eukaryotic translation initiation factor 4F complex assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0002181-&&-cytoplasmic translation|cellular_component-&-1&-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0004386-&&-helicase activity-%%-GO:0034057-&&-RNA strand-exchange activity-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0033592-&&-RNA strand annealing activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:EIF4B			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa03013-&&-RNA transport-%%-hsa04150-&&-mTOR signaling pathway	EIF4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4B	0.498136646	0.42508874	0.12048193	86	4	0.018383548	FALSE	12.81081081	EIF4B	EIF4B	208.8690476	14.08692049	0	85	0	0.77459167	FALSE	1	EIF4B	337330	Infinity	0.05152856
792943	taxon:9606	2.29320939	424.5848575	3.49E-04	181104	1902	fatty acid synthase	gene	biological_process-&-1&-GO:0030879-&&-mammary gland development-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006084-&&-acetyl-CoA metabolic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0015939-&&-pantothenate metabolic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042587-&&-glycogen granule-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004320-&&-oleoyl-[acyl-carrier-protein] hydrolase activity-%%-GO:0004313-&&-[acyl-carrier-protein] S-acetyltransferase activity-%%-GO:0004315-&&-3-oxoacyl-[acyl-carrier-protein] synthase activity-%%-GO:0008144-&&-drug binding-%%-GO:0102132-&&-3-oxo-pimeloyl-[acp] methyl ester reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding-%%-GO:0047117-&&-enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity-%%-GO:0004317-&&-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity-%%-GO:0016295-&&-myristoyl-[acyl-carrier-protein] hydrolase activity-%%-GO:0016296-&&-palmitoyl-[acyl-carrier-protein] hydrolase activity-%%-GO:0047451-&&-3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity-%%-GO:0070402-&&-NADPH binding-%%-GO:0031177-&&-phosphopantetheine binding-%%-GO:0004312-&&-fatty acid synthase activity-%%-GO:0004314-&&-[acyl-carrier-protein] S-malonyltransferase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0004319-&&-enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity-%%-GO:0004316-&&-3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	G:9606:FASN	FASN	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa01212-&&-Fatty acid metabolism	FASN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FASN	0.499532856	0.43607008	0.12335055	86	4	0.020371865	FALSE	14.53030303	FASN	FASN	234.702381	15.03668572	0	85	0	0.7844651	FALSE	1	FASN	562654	Infinity	0.05316813
793166	taxon:9606	2.29746337	735.1500994	4.18E-04	180605	1902	G protein subunit beta 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0065009-&&-regulation of molecular function|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0051020-&&-GTPase binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0032403-&&-protein complex binding	G:9606:GNB2			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNB2	0.499844188	0.43526265	0.09411765	86	4	0.014876186	FALSE	9.75	GNB2	GNB2	184.6395349	10.8311913	0	86	0	0.78375611	FALSE	0	GNB2	666514	Infinity	0.04202938
793158	taxon:9606	2.40255239	815.6125457	9.95E-04	180617	1902	G protein subunit alpha i2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0051301-&&-cell division-%%-GO:0001973-&&-adenosine receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0007584-&&-response to nutrient-%%-GO:0050805-&&-negative regulation of synaptic transmission-%%-GO:0007049-&&-cell cycle-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0051924-&&-regulation of calcium ion transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNAI2			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05012-&&-Parkinson disease-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04916-&&-Melanogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04727-&&-GABAergic synapse-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04540-&&-Gap junction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAI2	0.475400119	0.41622401	0.05854993	86	4	0.007357481	FALSE	5.857142857	GNAI2	GNAI2	110.0116279	6.639527422	0	86	0	0.76624127	FALSE	0	GNAI2	1006468	Infinity	0.02955114
789170	taxon:9606	2.33700961	995.418844	3.26E-04	176053	1902	metastasis associated 1	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:1902499-&&-positive regulation of protein autoubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0006302-&&-double-strand break repair-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0016575-&&-histone deacetylation-%%-GO:0045475-&&-locomotor rhythm-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001047-&&-core promoter binding	G:9606:MTA1				MTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTA1	0.493690366	0.42789726	0.13597811	86	4	0.011396051	FALSE	12.55357143	MTA1	MTA1	162.5116279	13.10967373	0	86	0	0.77716506	FALSE	0	MTA1	579934	Infinity	0.03910289
789865	taxon:9606	2.31038286	706.9284889	2.09E-04	174487	1902	GCN1, eIF2 alpha kinase activator homolog	gene	biological_process-&-1&-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0006417-&&-regulation of translation-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:1990253-&&-cellular response to leucine starvation-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005840-&&-ribosome-%%-GO:0016020-&&-membrane-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding	G:9606:GCN1				GCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCN1	0.499377335	0.4328287	0.11326949	86	4	0.018555526	FALSE	11.66666667	GCN1	GCN1	229.7093023	12.45412121	0	86	0	0.78160286	FALSE	0	GCN1	525968	Infinity	0.05333823
789957	taxon:9606	2.38537892	648.9413207	1.63E-04	174251	1902	UTP14A small subunit processome component	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0032040-&&-small-subunit processome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:UTP14A			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	UTP14A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP14A	0.48962149	0.41922061	0.13187415	86	4	0.012855801	FALSE	12.32786885	UTP14A	UTP14A	148.6511628	12.90045557	0	86	0	0.76910351	FALSE	0	UTP14A	316530	Infinity	0.03865788
789990	taxon:9606	2.5389948	751.0146115	1.71E-04	174176	1902	centrosomal protein 162	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005879-&&-axonemal microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP162				CEP162	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP162	0.460522538	0.39385666	0.12612859	86	4	0.006281149	FALSE	10.50877193	CEP162	CEP162	97.41860465	11.55180309	0	86	0	0.74350087	FALSE	0	CEP162	273670	Infinity	0.03376247
790564	taxon:9606	2.39924374	826.0962714	1.60E-04	172125	1902	ring finger protein 11	gene	biological_process-&-1&-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0055037-&&-recycling endosome-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF11				RNF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF11	0.485325265	0.416798	0.12812225	85	4	0.009250723	FALSE	13.40298507	RNF11	RNF11	133.7710843	14.98835899	0	84	0	0.76679271	FALSE	1	RNF11	295148	Infinity	0.03574533
790789	taxon:9606	2.5240271	272.018733	2.96E-04	171192	1902	DNA methyltransferase 3 like	gene	biological_process-&-1&-GO:1905643-&&-positive regulation of DNA methylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006306-&&-DNA methylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0007141-&&-male meiosis I-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0032776-&&-DNA methylation on cytosine-%%-GO:1905642-&&-negative regulation of DNA methylation-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008047-&&-enzyme activator activity	G:9606:DNMT3L				DNMT3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT3L	0.455164586	0.39619226	0.09131653	85	4	0.010541365	FALSE	9.588235294	DNMT3L	DNMT3L	127.6705882	10.08720014	0	85	0	0.74599548	FALSE	0	DNMT3L	468418	Infinity	0.04249084
787354	taxon:9606	2.53663148	471.9870139	5.85E-04	179597	1902	melatonin receptor 1B	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007623-&&-circadian rhythm-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0042593-&&-glucose homeostasis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008502-&&-melatonin receptor activity	G:9606:MTNR1B	MTNR1B	TRUE	KEGG-&-1&-hsa04713-&&-Circadian entrainment-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	MTNR1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTNR1B	0.45581131	0.3942236	0.02879812	85	4	0.005508321	FALSE	5.731707317	MTNR1B	MTNR1B	75.55421687	6.222667671	0	84	0	0.74389475	FALSE	1	MTNR1B	657606	Infinity	0.02631801
787765	taxon:9606	2.26248621	557.1745741	2.31E-04	178820	1902	peptidylprolyl isomerase A	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0019076-&&-viral release from host cell-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0050900-&&-leukocyte migration-%%-GO:0045069-&&-regulation of viral genome replication-%%-GO:0034389-&&-lipid particle organization-%%-GO:0019058-&&-viral life cycle-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0030260-&&-entry into host cell-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0019064-&&-fusion of virus membrane with host plasma membrane-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0019061-&&-uncoating of virus-%%-GO:0019068-&&-virion assembly-%%-GO:0006278-&&-RNA-dependent DNA biosynthetic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046790-&&-virion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:PPIA			KEGG-&-1&-hsa04217-&&-Necroptosis	PPIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIA	0.503927113	0.44199164	0.1439906	85	4	0.019163564	FALSE	15.78787879	PPIA	PPIA	234.5421687	16.51627686	0	84	0	0.78958563	FALSE	1	PPIA	500406	Infinity	0.05090734
791895	taxon:9606	2.30534111	622.7594011	3.23E-04	182913	1902	adaptor related protein complex 2 beta 1 subunit	gene	biological_process-&-1&-GO:0048268-&&-clathrin coat assembly-%%-GO:0035904-&&-aorta development-%%-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0099590-&&-neurotransmitter receptor internalization-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0003281-&&-ventricular septum development-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0060976-&&-coronary vasculature development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0030276-&&-clathrin binding-%%-GO:0005048-&&-signal sequence binding-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0032403-&&-protein complex binding	G:9606:AP2B1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2B1	0.497672975	0.43377529	0.1535014	85	4	0.013767658	FALSE	13.86666667	AP2B1	AP2B1	192.3294118	14.76010571	0	85	0	0.78244315	FALSE	0	AP2B1	527220	Infinity	0.04432512
787807	taxon:9606	2.31054041	575.2502612	3.97E-04	178763	1902	protein kinase cAMP-dependent type I regulatory subunit alpha	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0001707-&&-mesoderm formation-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007143-&&-female meiotic division-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007596-&&-blood coagulation-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045214-&&-sarcomere organization-%%-GO:0045835-&&-negative regulation of meiotic nuclear division|cellular_component-&-1&-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0001772-&&-immunological synapse-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0016020-&&-membrane-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0097546-&&-ciliary base-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0004862-&&-cAMP-dependent protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding	G:9606:PRKAR1A			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	PRKAR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAR1A	0.499066584	0.43279918	0.07846018	85	4	0.012786672	FALSE	9.607142857	PRKAR1A	PRKAR1A	170.5662651	10.12680061	0	84	0	0.7815766	FALSE	1	PRKAR1A	559656	Infinity	0.0395478
788150	taxon:9606	2.52512998	405.3959369	4.58E-04	178156	1902	RAB5A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:2000300-&&-regulation of synaptic vesicle exocytosis-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0036465-&&-synaptic vesicle recycling-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0007596-&&-blood coagulation-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0006897-&&-endocytosis-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0006909-&&-phagocytosis-%%-GO:0051036-&&-regulation of endosome size-%%-GO:2000286-&&-receptor internalization involved in canonical Wnt signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0043679-&&-axon terminus-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0043195-&&-terminal bouton-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0036477-&&-somatodendritic compartment-%%-GO:0098559-&&-cytoplasmic side of early endosome membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0001726-&&-ruffle-%%-GO:0010008-&&-endosome membrane-%%-GO:0030425-&&-dendrite-%%-GO:0045121-&&-membrane raft-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding	G:9606:RAB5A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome-%%-hsa05146-&&-Amoebiasis-%%-hsa05152-&&-Tuberculosis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	RAB5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB5A	0.445308162	0.39601922	0.04525419	85	4	0.003797177	FALSE	6.921052632	RAB5A	RAB5A	73.04819277	7.258829207	0	84	0	0.74581167	FALSE	1	RAB5A	425100	Infinity	0.02471351
792304	taxon:9606	2.32960454	478.3285152	4.35E-04	182258	1902	CCAAT/enhancer binding protein beta	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0072574-&&-hepatocyte proliferation-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006954-&&-inflammatory response-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0006955-&&-immune response-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006953-&&-acute-phase response-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0045408-&&-regulation of interleukin-6 biosynthetic process-%%-GO:0097421-&&-liver regeneration-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0007613-&&-memory-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036488-&&-CHOP-C/EBP complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0044389-&&-ubiquitin-like protein ligase binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:CEBPB			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05152-&&-Tuberculosis	CEBPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPB	0.485031751	0.42925741	0.19541581	85	4	0.010674826	FALSE	19.98387097	CEBPB	CEBPB	161.5301205	21.73191404	0	84	0	0.77839924	FALSE	1	CEBPB	563468	Infinity	0.0384601
788230	taxon:9606	2.44257129	509.7907241	2.67E-04	178043	1902	serum/glucocorticoid regulated kinase 1	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007616-&&-long-term memory-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0060453-&&-regulation of gastric acid secretion-%%-GO:0006950-&&-response to stress-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0032411-&&-positive regulation of transporter activity-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0070294-&&-renal sodium ion absorption|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0005524-&&-ATP binding	G:9606:SGK1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04150-&&-mTOR signaling pathway	SGK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGK1	0.47894894	0.40940463	0.06406112	85	4	0.009679356	FALSE	8.296296296	SGK1	SGK1	119.1084337	8.757874525	0	84	0	0.75957145	FALSE	1	SGK1	356412	Infinity	0.03415614
792535	taxon:9606	2.34315425	663.7961157	1.74E-04	181841	1902	capping actin protein of muscle Z-line alpha subunit 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0071203-&&-WASH complex-%%-GO:0008290-&&-F-actin capping protein complex-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CAPZA1			KEGG-&-1&-hsa04144-&&-Endocytosis	CAPZA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPZA1	0.498756219	0.42677515	0.14257703	85	4	0.018282793	FALSE	13.69444444	CAPZA1	CAPZA1	220.3058824	14.71702483	0	85	0	0.77614096	FALSE	0	CAPZA1	413568	Infinity	0.05376387
788616	taxon:9606	2.33291319	607.1874994	2.71E-04	177303	1902	peroxiredoxin 2	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0016209-&&-antioxidant activity	G:9606:PRDX2	PRDX2	TRUE		PRDX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX2	0.492628993	0.42864861	0.1354687	85	4	0.012845431	FALSE	13.80357143	PRDX2	PRDX2	166.4096386	15.02912872	0	84	0	0.7778478	FALSE	1	PRDX2	465946	Infinity	0.03998981
792857	taxon:9606	2.38002206	400.0951107	9.34E-05	181260	1902	ERG, ETS transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016477-&&-cell migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003199-&&-endocardial cushion to mesenchymal transition involved in heart valve formation-%%-GO:0007165-&&-signal transduction-%%-GO:2000504-&&-positive regulation of blood vessel remodeling-%%-GO:0007275-&&-multicellular organism development-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ERG			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer	ERG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERG	0.496902107	0.42016417	0.13664414	85	4	0.019158635	FALSE	14.59722222	ERG	ERG	176.9879518	15.10915086	0	84	0	0.76999632	FALSE	1	ERG	220260	Infinity	0.04567677
792874	taxon:9606	2.38112494	443.7771176	3.65E-04	181241	1902	ETS proto-oncogene 1, transcription factor	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061614-&&-pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0044849-&&-estrous cycle-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0060055-&&-angiogenesis involved in wound healing-%%-GO:0030578-&&-PML body organization-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0021983-&&-pituitary gland development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0032355-&&-response to estradiol-%%-GO:1904996-&&-positive regulation of leukocyte adhesion to vascular endothelial cell-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007565-&&-female pregnancy-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0006955-&&-immune response-%%-GO:0010715-&&-regulation of extracellular matrix disassembly-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0021854-&&-hypothalamus development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0048870-&&-cell motility|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:ETS1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05211-&&-Renal cell carcinoma	ETS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETS1	0.484885127	0.41996956	0.10578901	85	4	0.009448018	FALSE	12.94230769	ETS1	ETS1	137.1686747	13.50774909	0	84	0	0.76981251	FALSE	1	ETS1	457712	Infinity	0.03545878
789095	taxon:9606	2.36915078	475.2126571	2.51E-04	176203	1902	far upstream element binding protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:FUBP1				FUBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FUBP1	0.49202454	0.42209217	0.11596639	85	4	0.015053486	FALSE	11.67924528	FUBP1	FUBP1	181.2470588	12.23655766	0	85	0	0.7718082	FALSE	0	FUBP1	474792	Infinity	0.04602489
789258	taxon:9606	2.37119899	569.6004876	1.91E-04	175884	1902	eukaryotic translation initiation factor 3 subunit I	gene	biological_process-&-1&-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3I			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3I	0.493083308	0.42172757	0.1464986	85	4	0.016147548	FALSE	13.34920635	EIF3I	EIF3I	184.3647059	14.22584223	0	85	0	0.77146683	FALSE	0	EIF3I	392294	Infinity	0.04698685
789555	taxon:9606	2.34866866	536.5287817	4.49E-04	175195	1902	kelch like ECH associated protein 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045604-&&-regulation of epidermal cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010499-&&-proteasomal ubiquitin-independent protein catabolic process-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005884-&&-actin filament-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:KEAP1	KEAP1	TRUE	KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma	KEAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KEAP1	0.485031751	0.42577313	0.06553041	85	4	0.008067471	FALSE	8.956521739	KEAP1	KEAP1	132	9.415954305	0	84	0	0.77522189	FALSE	1	KEAP1	541204	Infinity	0.03247258
789713	taxon:9606	2.33370096	884.103392	1.71E-04	174846	1902	acidic nuclear phosphoprotein 32 family member B	gene	biological_process-&-1&-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0048839-&&-inner ear development-%%-GO:0001944-&&-vasculature development-%%-GO:0060021-&&-palate development-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0021591-&&-ventricular system development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0070063-&&-RNA polymerase binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding	G:9606:ANP32B				ANP32B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANP32B	0.499844188	0.42850392	0.15238095	85	4	0.019618127	FALSE	14.36111111	ANP32B	ANP32B	223.7529412	15.01229562	0	85	0	0.77771651	FALSE	0	ANP32B	466934	Infinity	0.0537367
789759	taxon:9606	2.38191271	644.5385105	1.59E-04	174759	1902	RAD50 double strand break repair protein	gene	biological_process-&-1&-GO:0000019-&&-regulation of mitotic recombination-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0070192-&&-chromosome organization involved in meiotic cell cycle-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0046939-&&-nucleotide phosphorylation-%%-GO:0000723-&&-telomere maintenance-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000732-&&-strand displacement-%%-GO:0006281-&&-DNA repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0016032-&&-viral process-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006310-&&-DNA recombination-%%-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0031860-&&-telomeric 3' overhang formation|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0030870-&&-Mre11 complex-%%-GO:0016020-&&-membrane-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0043047-&&-single-stranded telomeric DNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0000014-&&-single-stranded DNA endodeoxyribonuclease activity-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004017-&&-adenylate kinase activity	G:9606:RAD50			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining-%%-hsa04218-&&-Cellular senescence-%%-hsa03440-&&-Homologous recombination	RAD50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD50	0.493234932	0.41983067	0.16302521	85	4	0.019849565	FALSE	15.69014085	RAD50	RAD50	228.4117647	16.60312422	0	85	0	0.76968121	FALSE	0	RAD50	390304	Infinity	0.05908531
790022	taxon:9606	2.57507484	334.0261252	4.22E-04	174073	1902	RNA binding protein with multiple splicing	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006396-&&-RNA processing-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005685-&&-U1 snRNP-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0008143-&&-poly(A) binding-%%-GO:0030619-&&-U1 snRNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0035614-&&-snRNA stem-loop binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBPMS				RBPMS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBPMS	0.438131658	0.38833823	0.03349985	85	4	0.003733347	FALSE	6.03125	RBPMS	RBPMS	64.18072289	6.264285714	0	84	0	0.73748753	FALSE	1	RBPMS	413422	Infinity	0.02417382
791318	taxon:9606	2.78257444	64.11539581	2.11E-04	169202	1902	coenzyme Q9	gene	biological_process-&-1&-GO:0006744-&&-ubiquinone biosynthetic process-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008289-&&-lipid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:COQ9				COQ9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COQ9	0.374503852	0.35937942	0.05149051	84	4	0.001565974	FALSE	6.45	COQ9	COQ9	39.62195122	6.9375	0	83	0	0.70290426	FALSE	1	COQ9	215984	Infinity	0.02794499
791837	taxon:9606	2.4394202	269.9400774	0.00113543	182993	1902	alpha-2-macroglobulin	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0001869-&&-negative regulation of complement activation, lectin pathway-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0022617-&&-extracellular matrix disassembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0019959-&&-interleukin-8 binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0043120-&&-tumor necrosis factor binding	G:9606:A2M			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	A2M	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-A2M	0.46344987	0.40993348	0.05179163	84	4	0.005121209	FALSE	5.657142857	A2M	A2M	90.42682927	5.997515948	0	83	0	0.76009663	FALSE	1	A2M	1193248	Infinity	0.02589495
791999	taxon:9606	2.44934615	258.4812809	3.34E-04	182749	1902	B-cell CLL/lymphoma 6	gene	biological_process-&-1&-GO:0050776-&&-regulation of immune response-%%-GO:0048821-&&-erythrocyte development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0048294-&&-negative regulation of isotype switching to IgE isotypes-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0042092-&&-type 2 immune response-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043380-&&-regulation of memory T cell differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0002467-&&-germinal center formation-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032764-&&-negative regulation of mast cell cytokine production-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0045629-&&-negative regulation of T-helper 2 cell differentiation-%%-GO:0030183-&&-B cell differentiation|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001161-&&-intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:BCL6			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer	BCL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL6	0.475259259	0.40827222	0.09996989	84	4	0.008545903	FALSE	12.97674419	BCL6	BCL6	127.902439	13.52136422	0	83	0	0.75844231	FALSE	1	BCL6	443244	Infinity	0.03704489
787922	taxon:9606	2.44194107	697.4406374	1.23E-04	178604	1902	prothymosin, alpha	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PTMA				PTMA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTMA	0.489322758	0.40951029	0.12994836	84	4	0.014976134	FALSE	11.74647887	PTMA	PTMA	169.2738095	12.36160305	0	84	0	0.75967649	FALSE	0	PTMA	289124	Infinity	0.04851643
788748	taxon:9606	2.32456279	625.5946935	4.86E-04	177044	1902	titin	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0051592-&&-response to calcium ion-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0030241-&&-skeletal muscle myosin thick filament assembly-%%-GO:0048769-&&-sarcomerogenesis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045214-&&-sarcomere organization-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0035995-&&-detection of muscle stretch-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0048739-&&-cardiac muscle fiber development-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc-%%-GO:0005859-&&-muscle myosin complex-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0031430-&&-M band-%%-GO:0031674-&&-I band-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0051371-&&-muscle alpha-actinin binding-%%-GO:0042805-&&-actinin binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0031433-&&-telethonin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0097493-&&-structural molecule activity conferring elasticity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0043621-&&-protein self-association-%%-GO:0019899-&&-enzyme binding	G:9606:TTN			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)	TTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTN	0.496748219	0.43018842	0.09153869	84	4	0.013974076	FALSE	11.14285714	TTN	TTN	179.902439	11.84547643	0	83	0	0.77923954	FALSE	1	TTN	622958	Infinity	0.04267714
788941	taxon:9606	2.4495037	544.3374702	1.87E-04	160169	1902	TMEM189-UBE2V1 readthrough	gene		G:9606:TMEM189-UBE2V1				TMEM189-UBE2V1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM189-UBE2V1	0.478520286	0.40824596	0.12887684	84	4	0.008613356	FALSE	13.14285714	TMEM189-UBE2V1	TMEM189-UBE2V1	129.5243902	14.01553187	0	83	0	0.75841605	FALSE	1	TMEM189-UBE2V1	354892	Infinity	0.03759779
793125	taxon:9606	2.53017173	414.1130717	2.75E-04	180686	1902	growth hormone 1	gene	biological_process-&-1&-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0015758-&&-glucose transport-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0010535-&&-positive regulation of activation of JAK2 kinase activity-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0070977-&&-bone maturation-%%-GO:0032355-&&-response to estradiol-%%-GO:0060396-&&-growth hormone receptor signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031904-&&-endosome lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005131-&&-growth hormone receptor binding-%%-GO:0005148-&&-prolactin receptor binding-%%-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0046872-&&-metal ion binding	G:9606:GH1	GH1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	GH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GH1	0.465872785	0.39523009	0.05149051	84	4	0.009234563	FALSE	7.2	GH1	GH1	106.8658537	7.444599977	0	83	0	0.74497138	FALSE	1	GH1	429480	Infinity	0.0363693
793349	taxon:9606	2.30250512	728.8469727	2.02E-04	180258	1902	high mobility group AT-hook 1	gene	biological_process-&-1&-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0031936-&&-negative regulation of chromatin silencing-%%-GO:0006284-&&-base-excision repair-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090402-&&-oncogene-induced cell senescence-%%-GO:0009615-&&-response to virus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0035986-&&-senescence-associated heterochromatin focus assembly-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051169-&&-nuclear transport|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0035985-&&-senescence-associated heterochromatin focus|molecular_function-&-1&-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003680-&&-AT DNA binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0003677-&&-DNA binding	G:9606:HMGA1				HMGA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGA1	0.498291395	0.43430957	0.1394148	84	4	0.015440123	FALSE	12.97014925	HMGA1	HMGA1	188.8928571	13.68996386	0	84	0	0.78291581	FALSE	0	HMGA1	405502	Infinity	0.04335563
789422	taxon:9606	2.32566567	448.6717098	1.86E-04	175516	1902	BCL2 associated transcription factor 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:BCLAF1				BCLAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCLAF1	0.498291395	0.42998442	0.15863454	84	4	0.019416394	FALSE	14.265625	BCLAF1	BCLAF1	237.7857143	14.81843473	0	84	0	0.77905572	FALSE	0	BCLAF1	478586	Infinity	0.05635786
789460	taxon:9606	2.4178352	378.9530092	2.10E-04	175417	1902	H2A histone family member Y	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0007549-&&-dosage compensation-%%-GO:0006342-&&-chromatin silencing-%%-GO:1901837-&&-negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0001558-&&-regulation of cell growth-%%-GO:1902882-&&-regulation of response to oxidative stress-%%-GO:1902750-&&-negative regulation of cell cycle G2/M phase transition-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0061187-&&-regulation of chromatin silencing at rDNA-%%-GO:0033128-&&-negative regulation of histone phosphorylation-%%-GO:0071169-&&-establishment of protein localization to chromatin-%%-GO:0034184-&&-positive regulation of maintenance of mitotic sister chromatid cohesion-%%-GO:1904815-&&-negative regulation of protein localization to chromosome, telomeric region-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0061086-&&-negative regulation of histone H3-K27 methylation-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0001740-&&-Barr body-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000786-&&-nucleosome-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0001739-&&-sex chromatin-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0000182-&&-rDNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0010385-&&-double-stranded methylated DNA binding	G:9606:H2AFY			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	H2AFY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H2AFY	0.487389851	0.41359312	0.35513483	84	4	0.021886749	FALSE	32.27272727	H2AFY	H2AFY	227.9642857	34.00342294	0	84	0	0.76369413	FALSE	0	H2AFY	421312	Infinity	0.06258989
789729	taxon:9606	2.32298724	747.8196032	2.90E-04	174814	1902	programmed cell death 6	gene	biological_process-&-1&-GO:0051592-&&-response to calcium ion-%%-GO:0036324-&&-vascular endothelial growth factor receptor-2 signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006508-&&-proteolysis-%%-GO:0001525-&&-angiogenesis-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0034605-&&-cellular response to heat-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0051898-&&-negative regulation of protein kinase B signaling|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0060090-&&-binding, bridging-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity-%%-GO:0043495-&&-protein anchor-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PDCD6				PDCD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD6	0.49751861	0.4304802	0.11833785	84	4	0.014827633	FALSE	13.01612903	PDCD6	PDCD6	181.0121951	13.66860938	0	83	0	0.77950213	FALSE	1	PDCD6	470244	Infinity	0.04275639
789790	taxon:9606	2.39057823	457.6130619	2.40E-04	174672	1902	flotillin 1	gene	biological_process-&-1&-GO:0070528-&&-protein kinase C signaling-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0044854-&&-plasma membrane raft assembly-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:2000049-&&-positive regulation of cell-cell adhesion mediated by cadherin-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0034143-&&-regulation of toll-like receptor 4 signaling pathway-%%-GO:0002090-&&-regulation of receptor internalization-%%-GO:0007409-&&-axonogenesis-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:1903044-&&-protein localization to membrane raft-%%-GO:0032226-&&-positive regulation of synaptic transmission, dopaminergic-%%-GO:0060355-&&-positive regulation of cell adhesion molecule production-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0033227-&&-dsRNA transport-%%-GO:0001765-&&-membrane raft assembly-%%-GO:1901890-&&-positive regulation of cell junction assembly-%%-GO:0022617-&&-extracellular matrix disassembly|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016600-&&-flotillin complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0034451-&&-centriolar satellite-%%-GO:0042470-&&-melanosome-%%-GO:0030027-&&-lamellipodium-%%-GO:0005769-&&-early endosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane-%%-GO:0005901-&&-caveola-%%-GO:0042383-&&-sarcolemma-%%-GO:0005911-&&-cell-cell junction-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding	G:9606:FLOT1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	FLOT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLOT1	0.486502881	0.41830884	0.10298336	84	4	0.013511187	FALSE	11.48148148	FLOT1	FLOT1	173.25	12.0234857	0	84	0	0.76823696	FALSE	0	FLOT1	493364	Infinity	0.04555873
789841	taxon:9606	2.41436899	397.4461656	2.88E-04	174533	1902	mortality factor 4 like 1	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0016575-&&-histone deacetylation-%%-GO:0008283-&&-cell proliferation-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006342-&&-chromatin silencing-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:MORF4L1				MORF4L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MORF4L1	0.481971154	0.4141869	0.10990665	84	4	0.01018823	FALSE	10.60784314	MORF4L1	MORF4L1	131.4756098	11.0624672	0	83	0	0.76427183	FALSE	1	MORF4L1	421134	Infinity	0.0358925
790459	taxon:9606	2.35890972	615.1716307	3.51E-04	172793	1902	UBX domain protein 7	gene	cellular_component-&-1&-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:UBXN7				UBXN7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN7	0.490070272	0.42392466	0.14285714	84	4	0.010683369	FALSE	12.83928571	UBXN7	UBXN7	152.1190476	13.86382792	0	84	0	0.77351505	FALSE	0	UBXN7	531480	Infinity	0.03797039
787767	taxon:9606	2.34189381	928.1212975	2.61E-04	178819	1902	peptidylprolyl isomerase B	gene	biological_process-&-1&-GO:0060348-&&-bone development-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050821-&&-protein stabilization-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:1901873-&&-regulation of post-translational protein modification-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0044829-&&-positive regulation by host of viral genome replication|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0016020-&&-membrane-%%-GO:0032991-&&-macromolecular complex-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:PPIB				PPIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIB	0.497672975	0.42700484	0.1072583	83	4	0.014406439	FALSE	9.507692308	PPIB	PPIB	191.2048193	10.46543991	0	83	0	0.77635103	FALSE	0	PPIB	517042	Infinity	0.04651013
792067	taxon:9606	2.31117063	980.3941565	2.57E-04	166280	1902	translocase of inner mitochondrial membrane 50	gene	biological_process-&-1&-GO:0007006-&&-mitochondrial membrane organization-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0030150-&&-protein import into mitochondrial matrix-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005744-&&-mitochondrial inner membrane presequence translocase complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005134-&&-interleukin-2 receptor binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:TIMM50				TIMM50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMM50	0.497056089	0.43268116	0.09756098	83	4	0.015908536	FALSE	9.230769231	TIMM50	TIMM50	202.5421687	9.992044289	0	83	0	0.78147156	FALSE	0	TIMM50	528158	Infinity	0.0469009
792173	taxon:9606	2.40018907	418.4972245	2.38E-04	182479	1902	A-Raf proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:ARAF			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa04730-&&-Long-term depression-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04720-&&-Long-term potentiation-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	ARAF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARAF	0.482987052	0.41663385	0.08703704	83	4	0.009890512	FALSE	10.45283019	ARAF	ARAF	135.4691358	10.96415244	0	82	0	0.76663516	FALSE	1	ARAF	361262	Infinity	0.03603204
792248	taxon:9606	2.39924374	636.2395341	2.12E-04	182355	1902	ATPase H+ transporting V1 subunit B2	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:0015992-&&-proton transport-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport|cellular_component-&-1&-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0001726-&&-ruffle-%%-GO:0012505-&&-endomembrane system-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042470-&&-melanosome-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0015078-&&-hydrogen ion transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6V1B2			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05165-&&-Human papillomavirus infection	ATP6V1B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1B2	0.488726386	0.416798	0.1072583	83	4	0.010469233	FALSE	8.035087719	ATP6V1B2	ATP6V1B2	133.4096386	8.454965537	0	83	0	0.76679271	FALSE	0	ATP6V1B2	341486	Infinity	0.03544358
792291	taxon:9606	2.31747282	566.1037335	1.67E-04	182277	1902	cyclin dependent kinase inhibitor 1B	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048839-&&-inner ear development-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:1902746-&&-regulation of lens fiber cell differentiation-%%-GO:0001890-&&-placenta development-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0009749-&&-response to glucose-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0043200-&&-response to amino acid-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0042493-&&-response to drug-%%-GO:0048102-&&-autophagic cell death-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0006813-&&-potassium ion transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0032355-&&-response to estradiol-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0051271-&&-negative regulation of cellular component movement|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005072-&&-transforming growth factor beta receptor, cytoplasmic mediator activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0032403-&&-protein complex binding	G:9606:CDKN1B	CDKN1B	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05226-&&-Gastric cancer	CDKN1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN1B	0.498911353	0.43150452	0.15221863	83	4	0.013652879	FALSE	13.35384615	CDKN1B	CDKN1B	186.2650602	14.18268411	0	83	0	0.7804212	FALSE	0	CDKN1B	358044	Infinity	0.04364224
788214	taxon:9606	2.43752954	385.8859686	1.89E-04	178064	1902	RELB proto-oncogene, NF-kB subunit	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0071470-&&-cellular response to osmotic stress-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0045063-&&-T-helper 1 cell differentiation-%%-GO:0034097-&&-response to cytokine-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006954-&&-inflammatory response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding	G:9606:RELB	RELB	TRUE	KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway	RELB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RELB	0.487389851	0.41025144	0.12407407	83	4	0.013855564	FALSE	11.875	RELB	RELB	146.9506173	12.13852846	0	82	0	0.76041174	FALSE	1	RELB	307734	Infinity	0.04176405
792539	taxon:9606	2.31479439	720.5906087	1.98E-04	181838	1902	capping actin protein of muscle Z-line beta subunit	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0051490-&&-negative regulation of filopodium assembly-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0010591-&&-regulation of lamellipodium assembly-%%-GO:0007596-&&-blood coagulation-%%-GO:0030036-&&-actin cytoskeleton organization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0008290-&&-F-actin capping protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0071203-&&-WASH complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0030017-&&-sarcomere|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding	G:9606:CAPZB			KEGG-&-1&-hsa04144-&&-Endocytosis	CAPZB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPZB	0.499844188	0.43200381	0.136938	83	4	0.01728964	FALSE	12.68656716	CAPZB	CAPZB	223.4939759	13.75477997	0	83	0	0.7808676	FALSE	0	CAPZB	442942	Infinity	0.0522154
792547	taxon:9606	2.45360013	438.6356	3.12E-04	181830	1902	caspase 7	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006508-&&-proteolysis-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity	G:9606:CASP7			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05133-&&-Pertussis-%%-hsa05134-&&-Legionellosis	CASP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP7	0.477807566	0.40756437	0.09351852	83	4	0.007024811	FALSE	9.26	CASP7	CASP7	105.7530864	9.665080061	0	82	0	0.75773331	FALSE	1	CASP7	397568	Infinity	0.03090388
788565	taxon:9606	2.48479597	505.6550496	1.30E-04	177421	1902	TATA-box binding protein associated factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010767-&&-regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage-%%-GO:1902806-&&-regulation of cell cycle G1/S phase transition-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:1905524-&&-negative regulation of protein autoubiquitination-%%-GO:2000825-&&-positive regulation of androgen receptor activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0036369-&&-transcription factor catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0030901-&&-midbrain development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0016573-&&-histone acetylation-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0060260-&&-regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001129-&&-RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly-%%-GO:0005524-&&-ATP binding-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:1905502-&&-acetyl-CoA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0061628-&&-H3K27me3 modified histone binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:TAF1			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF1	0.464658169	0.40244753	0.20185185	83	4	0.015198695	FALSE	18.3968254	TAF1	TAF1	180.1111111	19.44926614	0	82	0	0.75253401	FALSE	1	TAF1	301218	Infinity	0.05571981
788725	taxon:9606	2.47518513	529.3862499	2.00E-04	177118	1902	TNF receptor associated factor 3	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045087-&&-innate immune response-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030162-&&-regulation of proteolysis-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0008063-&&-Toll signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0007165-&&-signal transduction-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032648-&&-regulation of interferon-beta production-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0050688-&&-regulation of defense response to virus-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031996-&&-thioesterase binding	G:9606:TRAF3			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway	TRAF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF3	0.471903501	0.40401018	0.09660494	83	4	0.006753022	FALSE	10.64	TRAF3	TRAF3	105.5432099	11.19012358	0	82	0	0.75413581	FALSE	1	TRAF3	295054	Infinity	0.03206875
788819	taxon:9606	2.46573184	238.5309705	2.22E-04	176814	1902	ubiquitin conjugating enzyme E2 E1	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0032020-&&-ISG15-protein conjugation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042296-&&-ISG15 transferase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2E1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2E1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E1	0.477380952	0.40555911	0.04135802	83	4	0.0066783	FALSE	6.710526316	UBE2E1	UBE2E1	109.0617284	6.89427663	0	82	0	0.75571136	FALSE	1	UBE2E1	394130	Infinity	0.03267734
793227	taxon:9606	2.27162439	544.1811295	3.49E-04	180496	1902	DnaJ heat shock protein family (Hsp40) member B1	gene	biological_process-&-1&-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0097201-&&-negative regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0051087-&&-chaperone binding	G:9606:DNAJB1			KEGG-&-1&-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB1	0.499221911	0.44021362	0.12224508	83	4	0.01229387	FALSE	11.61818182	DNAJB1	DNAJB1	184.5903615	12.28665348	0	83	0	0.7880626	FALSE	0	DNAJB1	606132	Infinity	0.04060599
789443	taxon:9606	2.41137545	644.1833274	2.64E-04	175454	1902	FMR1 autosomal homolog 2	gene	biological_process-&-1&-GO:0017148-&&-negative regulation of translation|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005844-&&-polysome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:FXR2			KEGG-&-1&-hsa03013-&&-RNA transport	FXR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FXR2	0.485472155	0.41470108	0.06820988	83	4	0.008691882	FALSE	7.826086957	FXR2	FXR2	135.617284	8.425372124	0	82	0	0.76477076	FALSE	1	FXR2	418324	Infinity	0.03682904
789705	taxon:9606	2.5689302	547.1834015	1.87E-04	174853	1902	Sjogren syndrome/scleroderma autoantigen 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SSSCA1				SSSCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSSCA1	0.452851496	0.3892671	0.07407407	83	4	0.00564384	FALSE	6.6875	SSSCA1	SSSCA1	82.01234568	7.055308409	0	82	0	0.73851163	FALSE	1	SSSCA1	241156	Infinity	0.03030469
790091	taxon:9606	2.38411848	872.9972868	2.17E-04	173893	1902	glucosidase II alpha subunit	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0017177-&&-glucosidase II complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0033919-&&-glucan 1,3-alpha-glucosidase activity	G:9606:GANAB			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	GANAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GANAB	0.491572173	0.41944224	0.11166618	83	4	0.012850247	FALSE	9.93442623	GANAB	GANAB	173.6987952	10.7843928	0	83	0	0.76931359	FALSE	0	GANAB	434348	Infinity	0.0450518
790691	taxon:9606	2.40853947	320.0922024	1.06E-04	171466	1902	ubiquitin like with PHD and ring finger domains 1	gene	biological_process-&-1&-GO:0010390-&&-histone monoubiquitination-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000373-&&-positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0090308-&&-regulation of methylation-dependent chromatin silencing-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0007049-&&-cell cycle-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0000792-&&-heterochromatin-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000791-&&-euchromatin|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0042393-&&-histone binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031493-&&-nucleosomal histone binding-%%-GO:0044729-&&-hemi-methylated DNA-binding	G:9606:UHRF1				UHRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UHRF1	0.491271057	0.41518938	0.26677215	82	4	0.020772802	FALSE	25.375	UHRF1	UHRF1	236.4125	26.60917871	0	81	0	0.76524342	FALSE	1	UHRF1	269562	Infinity	0.06377496
787125	taxon:9606	2.49204349	252.838673	3.02E-04	180017	1902	forkhead box K2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:FOXK2				FOXK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXK2	0.463717838	0.40127711	0.08822644	82	4	0.00706957	FALSE	7.875	FOXK2	FOXK2	108.0731707	8.130113746	0	82	0	0.75132609	FALSE	0	FOXK2	362104	Infinity	0.03355079
787228	taxon:9606	2.32598078	266.3639425	2.89E-04	179828	1902	inositol polyphosphate phosphatase like 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0097178-&&-ruffle assembly-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0032868-&&-response to insulin-%%-GO:0046856-&&-phosphatidylinositol dephosphorylation-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007015-&&-actin filament organization-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0009791-&&-post-embryonic development-%%-GO:0002376-&&-immune system process-%%-GO:0007155-&&-cell adhesion-%%-GO:0001958-&&-endochondral ossification-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030175-&&-filopodium-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0052659-&&-inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity-%%-GO:0034485-&&-phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	G:9606:INPPL1			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa00562-&&-Inositol phosphate metabolism	INPPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INPPL1	0.492628993	0.42992617	0.155676	82	4	0.013306419	FALSE	15.01851852	INPPL1	INPPL1	177.1829268	15.52427272	0	82	0	0.7790032	FALSE	0	INPPL1	437220	Infinity	0.04209041
791760	taxon:9606	2.50527808	558.2207691	1.11E-04	166991	1902	SprT-like N-terminal domain	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0019985-&&-translesion synthesis-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0031398-&&-positive regulation of protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0043130-&&-ubiquitin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:SPRTN	SPRTN	TRUE		SPRTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRTN	0.480815348	0.39915729	0.0788919	82	4	0.012327703	FALSE	7.921875	SPRTN	SPRTN	131.5731707	8.464263	0	82	0	0.74912032	FALSE	0	SPRTN	228646	Infinity	0.04251141
791973	taxon:9606	2.38443359	611.2710796	1.64E-04	182780	1902	autoimmune regulator	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032602-&&-chemokine production-%%-GO:0097536-&&-thymus epithelium morphogenesis-%%-GO:0006417-&&-regulation of translation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006955-&&-immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000410-&&-regulation of thymocyte migration-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0002509-&&-central tolerance induction to self antigen-%%-GO:0006959-&&-humoral immune response-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0002458-&&-peripheral T cell tolerance induction|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:AIRE			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05340-&&-Primary immunodeficiency	AIRE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIRE	0.495826893	0.41938681	0.17120253	82	4	0.019235855	FALSE	17.05405405	AIRE	AIRE	211.3875	17.5614728	0	81	0	0.76926107	FALSE	1	AIRE	339774	Infinity	0.05480744
788092	taxon:9606	2.3398456	458.5458557	1.98E-04	178253	1902	phosphoglycerate kinase 1	gene	biological_process-&-1&-GO:0016310-&&-phosphorylation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0061621-&&-canonical glycolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004618-&&-phosphoglycerate kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PGK1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	PGK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGK1	0.494298921	0.42737863	0.18247516	82	4	0.017023003	FALSE	18.20967742	PGK1	PGK1	199.6097561	18.92750665	0	82	0	0.7766924	FALSE	0	PGK1	383036	Infinity	0.04831996
792189	taxon:9606	2.35528596	855.7797477	2.50E-04	182457	1902	Rho GDP dissociation inhibitor alpha	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005094-&&-Rho GDP-dissociation inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARHGDIA			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption	ARHGDIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGDIA	0.494603762	0.42457689	0.10696203	82	4	0.012021332	FALSE	11.01587302	ARHGDIA	ARHGDIA	165.325	12.22521919	0	81	0	0.77411901	FALSE	1	ARHGDIA	432768	Infinity	0.04085517
792441	taxon:9606	2.2969907	380.7834585	3.71E-04	182015	1902	catenin alpha 1	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0034613-&&-cellular protein localization-%%-GO:0031103-&&-axon regeneration-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0043627-&&-response to estrogen-%%-GO:2001045-&&-negative regulation of integrin-mediated signaling pathway-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0007406-&&-negative regulation of neuroblast proliferation-%%-GO:0007568-&&-aging-%%-GO:0008584-&&-male gonad development-%%-GO:0016264-&&-gap junction assembly-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0034332-&&-adherens junction organization-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007015-&&-actin filament organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0043297-&&-apical junction assembly-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005915-&&-zonula adherens-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0016342-&&-catenin complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0014704-&&-intercalated disc-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016600-&&-flotillin complex|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0003723-&&-RNA binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0045295-&&-gamma-catenin binding	G:9606:CTNNA1			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05226-&&-Gastric cancer	CTNNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNA1	0.496287129	0.43535222	0.10506329	82	4	0.011783842	FALSE	12.41509434	CTNNA1	CTNNA1	180.225	12.87461823	0	81	0	0.78383488	FALSE	1	CTNNA1	549522	Infinity	0.04100478
788534	taxon:9606	2.44824326	286.7518687	1.77E-04	161106	1902	ubiquitin conjugating enzyme E2 E4 pseudogene	gene		G:9606:UBE2E4P				UBE2E4P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E4P	0.47880597	0.40845614	0.08227848	82	4	0.00894957	FALSE	10.18604651	UBE2E4P	UBE2E4P	126.8375	10.51140719	0	81	0	0.75862612	FALSE	1	UBE2E4P	346078	Infinity	0.03671129
792722	taxon:9606	2.42114385	364.2325441	7.72E-05	181496	1902	dyskerin pseudouridine synthase 1	gene	biological_process-&-1&-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0090669-&&-telomerase RNA stabilization-%%-GO:0006396-&&-RNA processing-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0031120-&&-snRNA pseudouridine synthesis-%%-GO:1990481-&&-mRNA pseudouridine synthesis-%%-GO:0006364-&&-rRNA processing-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0031118-&&-rRNA pseudouridine synthesis-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0000495-&&-box H/ACA snoRNA 3'-end processing-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere|cellular_component-&-1&-GO:0090661-&&-box H/ACA telomerase RNP complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0031429-&&-box H/ACA snoRNP complex-%%-GO:0072589-&&-box H/ACA scaRNP complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003720-&&-telomerase activity-%%-GO:0009982-&&-pseudouridine synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0034513-&&-box H/ACA snoRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding	G:9606:DKC1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	DKC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DKC1	0.488131467	0.41302792	0.20316456	82	4	0.016081028	FALSE	16.88888889	DKC1	DKC1	180.0625	17.56767897	0	81	0	0.76314269	FALSE	1	DKC1	187496	Infinity	0.04964158
788744	taxon:9606	2.51000473	715.7882006	2.62E-04	177051	1902	tetratricopeptide repeat domain 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:TTC1				TTC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC1	0.465737515	0.39840562	0.07648299	82	4	0.009732502	FALSE	5.907407407	TTC1	TTC1	116.6219512	6.238809574	0	82	0	0.74833255	FALSE	0	TTC1	411950	Infinity	0.03821325
788813	taxon:9606	2.412951	850.4342885	1.72E-04	176823	1902	ubiquitin A-52 residue ribosomal protein fusion product 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0017085-&&-response to insecticide-%%-GO:0019058-&&-viral life cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0019068-&&-virion assembly-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006413-&&-translational initiation-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0019083-&&-viral transcription-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006364-&&-rRNA processing-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:UBA52			KEGG-&-1&-hsa03010-&&-Ribosome	UBA52	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA52	0.485472155	0.4144303	0.18734177	82	4	0.018120218	FALSE	18.45833333	UBA52	UBA52	167.775	19.3018105	0	81	0	0.76450817	FALSE	1	UBA52	312274	Infinity	0.0457515
788864	taxon:9606	2.4658894	359.5455747	1.84E-04	176739	1902	voltage dependent anion channel 3	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0006820-&&-anion transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:1903959-&&-regulation of anion transmembrane transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008308-&&-voltage-gated anion channel activity-%%-GO:0015288-&&-porin activity	G:9606:VDAC3			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04216-&&-Ferroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	VDAC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDAC3	0.473855244	0.40553319	0.15718157	82	4	0.00861954	FALSE	12.76595745	VDAC3	VDAC3	127.9390244	13.35194653	0	82	0	0.7556851	FALSE	0	VDAC3	313242	Infinity	0.03827072
789387	taxon:9606	2.40822436	289.2392182	2.47E-04	175599	1902	ribosomal protein S6 kinase A5	gene	biological_process-&-1&-GO:0043988-&&-histone H3-S28 phosphorylation-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0043987-&&-histone H3-S10 phosphorylation-%%-GO:0043990-&&-histone H2A-S1 phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:RPS6KA5			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	RPS6KA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA5	0.478234943	0.4152437	0.17946402	82	4	0.016279653	FALSE	19.22033898	RPS6KA5	RPS6KA5	191.7560976	19.67577007	0	82	0	0.76529594	FALSE	0	RPS6KA5	479464	Infinity	0.05184494
789611	taxon:9606	2.33133764	384.4383587	2.26E-04	175056	1902	nucleoporin 153	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0075732-&&-viral penetration into host nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0046832-&&-negative regulation of RNA export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005730-&&-nucleolus-%%-GO:0034399-&&-nuclear periphery-%%-GO:0044613-&&-nuclear pore central transport channel|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0043495-&&-protein anchor-%%-GO:0042802-&&-identical protein binding	G:9606:NUP153			KEGG-&-1&-hsa03013-&&-RNA transport	NUP153	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP153	0.496133622	0.4289383	0.1414557	82	4	0.011193051	FALSE	13.52727273	NUP153	NUP153	168.2625	14.26936121	0	81	0	0.77811039	FALSE	1	NUP153	365604	Infinity	0.04006609
789685	taxon:9606	2.44824326	286.7518687	1.77E-04	174899	1902	ubiquitin conjugating enzyme E2 E3	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2E3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2E3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E3	0.47880597	0.40845614	0.08227848	82	4	0.00894957	FALSE	10.18604651	UBE2E3	UBE2E3	126.8375	10.51140719	0	81	0	0.75862612	FALSE	1	UBE2E3	346078	Infinity	0.03671129
790447	taxon:9606	2.39089334	489.365921	6.41E-05	172838	1902	pre-mRNA processing factor 6	gene	biological_process-&-1&-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0006403-&&-RNA localization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0050681-&&-androgen receptor binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF6			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF6	0.497364341	0.41825371	0.26898734	82	4	0.019552141	FALSE	23.37662338	PRPF6	PRPF6	208.825	24.67159799	0	81	0	0.76818444	FALSE	1	PRPF6	181112	Infinity	0.05453774
787150	taxon:9606	2.33039231	617.4383899	2.15E-04	179977	1902	lamin B1	gene	cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0005638-&&-lamin filament-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0043274-&&-phospholipase binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:LMNB1			KEGG-&-1&-hsa04210-&&-Apoptosis	LMNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMNB1	0.499377335	0.4291123	0.11716975	81	4	0.016222531	FALSE	12.9	LMNB1	LMNB1	207.6202532	13.51538636	0	80	0	0.77826795	FALSE	1	LMNB1	423406	Infinity	0.04961033
787187	taxon:9606	2.50795651	384.3761612	3.65E-04	179904	1902	SMAD family member 9	gene	biological_process-&-1&-GO:0030902-&&-hindbrain development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0060348-&&-bone development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0001657-&&-ureteric bud development-%%-GO:0051216-&&-cartilage development-%%-GO:0030901-&&-midbrain development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0071141-&&-SMAD protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	G:9606:SMAD9			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD9	0.468868752	0.398731	0.03732554	81	4	0.006515277	FALSE	6.317073171	SMAD9	SMAD9	91.34177215	6.483823529	0	80	0	0.74867391	FALSE	1	SMAD9	389564	Infinity	0.02979941
791811	taxon:9606	2.37277454	660.5829863	2.78E-04	166766	1902	microtubule associated protein 1 light chain 3 alpha	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0000422-&&-mitophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0043278-&&-response to morphine-%%-GO:0010040-&&-response to iron(II) ion|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0044754-&&-autolysosome-%%-GO:0005829-&&-cytosol-%%-GO:0005770-&&-late endosome-%%-GO:0005874-&&-microtubule-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:MAP1LC3A			KEGG-&-1&-hsa04216-&&-Ferroptosis	MAP1LC3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1LC3A	0.487537994	0.42144754	0.08888889	81	4	0.010539384	FALSE	7.796610169	MAP1LC3A	MAP1LC3A	135.0617284	8.663639174	0	81	0	0.77120424	FALSE	0	MAP1LC3A	373444	Infinity	0.03452183
787899	taxon:9606	2.45281235	453.6522715	1.10E-04	178640	1902	proteasome 26S subunit, non-ATPase 8	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043248-&&-proteasome assembly-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex	G:9606:PSMD8			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD8	0.484445787	0.40769527	0.36481481	81	4	0.011502055	FALSE	31.01515152	PSMD8	PSMD8	146.691358	32.4067759	0	81	0	0.75786461	FALSE	0	PSMD8	205314	Infinity	0.04277603
792068	taxon:9606	2.43012447	435.9714594	2.45E-04	182667	1902	BUB1 mitotic checkpoint serine/threonine kinase B	gene	biological_process-&-1&-GO:0034501-&&-protein localization to kinetochore-%%-GO:0006915-&&-apoptotic process-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051754-&&-meiotic sister chromatid cohesion, centromeric-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007091-&&-metaphase/anaphase transition of mitotic cell cycle-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0051233-&&-spindle midzone-%%-GO:0000778-&&-condensed nuclear chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0000940-&&-condensed chromosome outer kinetochore|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:BUB1B			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	BUB1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB1B	0.483278096	0.41150156	0.12041545	81	4	0.009549429	FALSE	12	BUB1B	BUB1B	135.7468354	12.89920061	0	80	0	0.76164592	FALSE	1	BUB1B	354662	Infinity	0.03798531
788076	taxon:9606	2.46793761	223.5895787	2.90E-05	178279	1902	ribosomal protein L34	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPL34			KEGG-&-1&-hsa03010-&&-Ribosome	RPL34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL34	0.479378362	0.40519663	0.62006173	81	4	0.027117921	FALSE	50.78481013	RPL34	RPL34	191.4197531	51.89604033	0	81	0	0.75534373	FALSE	0	RPL34	95928	Infinity	0.05735913
792610	taxon:9606	2.35118954	405.0331686	2.56E-04	181726	1902	dual specificity tyrosine phosphorylation regulated kinase 1A	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0090312-&&-positive regulation of protein deacetylation-%%-GO:0007399-&&-nervous system development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0007623-&&-circadian rhythm-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0043621-&&-protein self-association-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0048156-&&-tau protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:DYRK1A				DYRK1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYRK1A	0.49338665	0.42531663	0.19344369	81	4	0.017690446	FALSE	19.96923077	DYRK1A	DYRK1A	221.0886076	20.67803137	0	80	0	0.77480174	FALSE	1	DYRK1A	445596	Infinity	0.05441916
788556	taxon:9606	2.43721443	605.8685957	2.86E-04	177445	1902	supervillin	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007519-&&-skeletal muscle tissue development|cellular_component-&-1&-GO:0071437-&&-invadopodium-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0036449-&&-microtubule minus-end-%%-GO:0030496-&&-midbody-%%-GO:0043034-&&-costamere-%%-GO:0002102-&&-podosome-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding	G:9606:SVIL				SVIL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SVIL	0.482406015	0.41030448	0.11080247	81	4	0.009274562	FALSE	11.96363636	SVIL	SVIL	128.8518519	12.74790549	0	81	0	0.76046426	FALSE	0	SVIL	395980	Infinity	0.03665749
788712	taxon:9606	2.37340476	424.811366	2.78E-04	177136	1902	tropomyosin 1 (alpha)	gene	biological_process-&-1&-GO:0031529-&&-ruffle organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0003065-&&-positive regulation of heart rate by epinephrine-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006937-&&-regulation of muscle contraction-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:1904753-&&-negative regulation of vascular associated smooth muscle cell migration-%%-GO:0006936-&&-muscle contraction-%%-GO:0007015-&&-actin filament organization-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045214-&&-sarcomere organization-%%-GO:0042060-&&-wound healing-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0060048-&&-cardiac muscle contraction|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005862-&&-muscle thin filament tropomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0032059-&&-bleb-%%-GO:0005856-&&-cytoskeleton-%%-GO:0032587-&&-ruffle membrane-%%-GO:0030017-&&-sarcomere-%%-GO:0005884-&&-actin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:TPM1	TPM1	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM1	0.488875343	0.42133563	0.11132749	81	4	0.009673798	FALSE	12.65384615	TPM1	TPM1	140.886076	13.20704686	0	80	0	0.77109921	FALSE	1	TPM1	410546	Infinity	0.03590961
792866	taxon:9606	2.42413739	438.6142702	2.30E-04	181248	1902	estrogen related receptor beta	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:ESRRB			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	ESRRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESRRB	0.477096966	0.41251787	0.09783951	81	4	0.013364226	FALSE	9.426229508	ESRRB	ESRRB	145.2962963	9.79529818	0	81	0	0.76264377	FALSE	0	ESRRB	355516	Infinity	0.04033951
792914	taxon:9606	2.45139436	335.0997816	2.15E-04	181161	1902	GRB2 associated binding protein 1	gene	biological_process-&-1&-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0008544-&&-epidermis development-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060711-&&-labyrinthine layer development-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0035728-&&-response to hepatocyte growth factor|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity	G:9606:GAB1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAB1	0.46238109	0.4079311	0.16790123	81	4	0.005564173	FALSE	14.22222222	GAB1	GAB1	115.4938272	14.86214921	0	81	0	0.75810094	FALSE	0	GAB1	304728	Infinity	0.03372707
789069	taxon:9606	2.54986608	348.8550258	3.83E-04	159866	1902	keratin associated protein 10-7	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KRTAP10-7				KRTAP10-7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-7	0.426822778	0.39217746	0.09250243	81	4	0.003048107	FALSE	8.5	KRTAP10-7	KRTAP10-7	71.58227848	9.169321371	0	80	0	0.74168899	FALSE	1	KRTAP10-7	405740	Infinity	0.02540639
793276	taxon:9606	2.37119899	251.7923533	1.56E-04	180387	1902	histone cluster 1 H1 family member c	gene	biological_process-&-1&-GO:0016584-&&-nucleosome positioning-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0080182-&&-histone H3-K4 trimethylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0000786-&&-nucleosome-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H1C				HIST1H1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1C	0.496133622	0.42172757	0.22530864	81	4	0.023651008	FALSE	19.83823529	HIST1H1C	HIST1H1C	256.8395062	20.46676098	0	81	0	0.77146683	FALSE	0	HIST1H1C	355534	Infinity	0.0652508
793367	taxon:9606	2.33874271	249.2754604	1.46E-04	180234	1902	heterogeneous nuclear ribonucleoprotein H3	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0008380-&&-RNA splicing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0030855-&&-epithelial cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPH3				HNRNPH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPH3	0.496748219	0.42758017	0.28562155	81	4	0.023000127	FALSE	26.53521127	HNRNPH3	HNRNPH3	251.3797468	27.20690258	0	80	0	0.77687621	FALSE	1	HNRNPH3	283340	Infinity	0.06077235
789341	taxon:9606	2.37734363	562.8592165	3.75E-04	175706	1902	large tumor suppressor kinase 1	gene	biological_process-&-1&-GO:0046620-&&-regulation of organ growth-%%-GO:0000819-&&-sister chromatid segregation-%%-GO:0001828-&&-inner cell mass cellular morphogenesis-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0035329-&&-hippo signaling-%%-GO:0001827-&&-inner cell mass cell fate commitment-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2000058-&&-regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:LATS1			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	LATS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LATS1	0.479952124	0.42063755	0.07594937	81	4	0.006770344	FALSE	8.448979592	LATS1	LATS1	122.0759494	9.017347147	0	80	0	0.77044273	FALSE	1	LATS1	463932	Infinity	0.03128854
789492	taxon:9606	2.43075469	404.069342	3.84E-04	175346	1902	CTR9 homolog, Paf1/RNA polymerase II complex component	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0001826-&&-inner cell mass cell differentiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:2001162-&&-positive regulation of histone H3-K79 methylation-%%-GO:2000653-&&-regulation of genetic imprinting-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0001832-&&-blastocyst growth-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016593-&&-Cdc73/Paf1 complex-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0042169-&&-SH2 domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0000993-&&-RNA polymerase II core binding	G:9606:CTR9				CTR9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTR9	0.473156342	0.41139487	0.11141975	81	4	0.010378449	FALSE	11.51111111	CTR9	CTR9	145.8888889	11.95823762	0	81	0	0.76154089	FALSE	0	CTR9	554678	Infinity	0.04102019
789629	taxon:9606	2.54829053	444.4470771	1.96E-04	175030	1902	abl interactor 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0001756-&&-somitogenesis-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0072673-&&-lamellipodium morphogenesis-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity|cellular_component-&-1&-GO:0030175-&&-filopodium-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005622-&&-intracellular-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031209-&&-SCAR complex-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0045296-&&-cadherin binding	G:9606:ABI1				ABI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABI1	0.455423055	0.39241993	0.11100292	81	4	0.006450442	FALSE	11.20833333	ABI1	ABI1	101.721519	11.81945793	0	80	0	0.74195158	FALSE	1	ABI1	265254	Infinity	0.03592164
789856	taxon:9606	2.43674177	281.1282396	8.86E-05	174501	1902	EBNA1 binding protein 2	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042273-&&-ribosomal large subunit biogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0034399-&&-nuclear periphery-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:EBNA1BP2				EBNA1BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EBNA1BP2	0.488131467	0.41038407	0.27253086	81	4	0.01981971	FALSE	23.78688525	EBNA1BP2	EBNA1BP2	192.2716049	24.45364	0	81	0	0.76054304	FALSE	0	EBNA1BP2	209606	Infinity	0.05443497
790262	taxon:9606	2.48668662	287.4058014	4.54E-04	173481	1902	NudC domain containing 3	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0032502-&&-developmental process-%%-GO:0006457-&&-protein folding-%%-GO:1905793-&&-protein localization to pericentriolar material|cellular_component-&-1&-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:NUDCD3				NUDCD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDCD3	0.464389114	0.40214154	0.04074074	81	4	0.005200692	FALSE	4.580645161	NUDCD3	NUDCD3	84.22222222	4.744444444	0	81	0	0.7522189	FALSE	0	NUDCD3	452256	Infinity	0.02613002
790386	taxon:9606	2.46856783	160.452159	1.55E-04	173148	1902	pleckstrin homology like domain family A member 3	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0051898-&&-negative regulation of protein kinase B signaling|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0010314-&&-phosphatidylinositol-5-phosphate binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding	G:9606:PHLDA3				PHLDA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHLDA3	0.468731736	0.40509318	0.04706264	81	4	0.00680495	FALSE	5.882352941	PHLDA3	PHLDA3	102.721519	6.060606061	0	80	0	0.7552387	FALSE	1	PHLDA3	239026	Infinity	0.03080435
787140	taxon:9606	2.5456121	264.088838	2.79E-04	179993	1902	DNA ligase 4	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006266-&&-DNA ligation-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000012-&&-single strand break repair-%%-GO:0045190-&&-isotype switching-%%-GO:0051301-&&-cell division-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0033153-&&-T cell receptor V(D)J recombination-%%-GO:0002328-&&-pro-B cell differentiation-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0051276-&&-chromosome organization-%%-GO:0033152-&&-immunoglobulin V(D)J recombination-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0007417-&&-central nervous system development-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0007049-&&-cell cycle-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051102-&&-DNA ligation involved in DNA recombination-%%-GO:0097680-&&-double-strand break repair via classical nonhomologous end joining-%%-GO:0010165-&&-response to X-ray-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0033151-&&-V(D)J recombination-%%-GO:2001252-&&-positive regulation of chromosome organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0071285-&&-cellular response to lithium ion|cellular_component-&-1&-GO:0032807-&&-DNA ligase IV complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005958-&&-DNA-dependent protein kinase-DNA ligase 4 complex-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0070419-&&-nonhomologous end joining complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016874-&&-ligase activity-%%-GO:0003910-&&-DNA ligase (ATP) activity	G:9606:LIG4			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining	LIG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIG4	0.458285714	0.39283283	0.03417722	80	4	0.007235363	FALSE	4.282051282	LIG4	LIG4	86.9375	4.527192982	0	80	0	0.74239798	FALSE	0	LIG4	319512	Infinity	0.03076855
787511	taxon:9606	2.44162597	580.8985161	2.09E-04	179309	1902	N-methylpurine DNA glycosylase	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0006307-&&-DNA dealkylation involved in DNA repair-%%-GO:0045007-&&-depurination|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003905-&&-alkylbase DNA N-glycosylase activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0052821-&&-DNA-7-methyladenine glycosylase activity-%%-GO:0019104-&&-DNA N-glycosylase activity-%%-GO:0008725-&&-DNA-3-methyladenine glycosylase activity-%%-GO:0052822-&&-DNA-3-methylguanine glycosylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043916-&&-DNA-7-methylguanine glycosylase activity	G:9606:MPG			KEGG-&-1&-hsa03410-&&-Base excision repair	MPG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPG	0.482551143	0.40956314	0.06227106	80	4	0.009529376	FALSE	7.672727273	MPG	MPG	130.1410256	8.044570489	0	79	0	0.75972901	FALSE	1	MPG	321324	Infinity	0.03722795
792118	taxon:9606	2.29825114	571.6666651	2.74E-04	182573	1902	coatomer protein complex subunit beta 1	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0016032-&&-viral process-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0070821-&&-tertiary granule membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:COPB1				COPB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPB1	0.49844624	0.43511346	0.11821512	80	4	0.012913565	FALSE	11.69811321	COPB1	COPB1	194.0897436	12.30926905	0	79	0	0.78362481	FALSE	1	COPB1	466702	Infinity	0.04416992
792952	taxon:9606	2.50181188	97.20770312	2.83E-05	164707	1902	ribosomal protein L10 like	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005844-&&-polysome-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL10L			KEGG-&-1&-hsa03010-&&-Ribosome	RPL10L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL10L	0.480815348	0.39971031	0.70031646	80	4	0.029461736	FALSE	57.44155844	RPL10L	RPL10L	205.9875	58.42210636	0	80	0	0.74969802	FALSE	0	RPL10L	69646	Infinity	0.06576868
788852	taxon:9606	2.43658421	393.4700906	1.89E-04	176748	1902	vav guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0030217-&&-T cell differentiation-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008361-&&-regulation of cell size-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0030676-&&-Rac guanyl-nucleotide exchange factor activity	G:9606:VAV1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04660-&&-T cell receptor signaling pathway	VAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAV1	0.473715298	0.4104106	0.18132911	80	4	0.008146383	FALSE	13.94444444	VAV1	VAV1	134.5875	14.6197322	0	80	0	0.7605693	FALSE	0	VAV1	319264	Infinity	0.03829681
789036	taxon:9606	2.37403498	561.2934666	1.91E-04	176313	1902	axin 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0060272-&&-embryonic skeletal joint morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0021881-&&-Wnt-activated signaling pathway involved in forebrain neuron fate commitment-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0021797-&&-forebrain anterior/posterior pattern specification-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030910-&&-olfactory placode formation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0048320-&&-axial mesoderm formation-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060823-&&-canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation-%%-GO:0048048-&&-embryonic eye morphogenesis-%%-GO:0055001-&&-muscle cell development-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0001743-&&-optic placode formation-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0019899-&&-enzyme binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding	G:9606:AXIN1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04934-&&-Cushing syndrome-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05226-&&-Gastric cancer	AXIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AXIN1	0.48902439	0.42122379	0.12487512	80	4	0.00952966	FALSE	12.0877193	AXIN1	AXIN1	147.6923077	12.76981604	0	79	0	0.77099417	FALSE	1	AXIN1	316346	Infinity	0.03772473
793303	taxon:9606	2.36442414	957.2927928	4.79E-04	180345	1902	HCK proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0007498-&&-mesoderm development-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045728-&&-respiratory burst after phagocytosis-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0071801-&&-regulation of podosome assembly-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0002758-&&-innate immune response-activating signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043299-&&-leukocyte degranulation-%%-GO:0007155-&&-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0002522-&&-leukocyte migration involved in immune response-%%-GO:0016032-&&-viral process-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005901-&&-caveola-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding	G:9606:HCK			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	HCK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HCK	0.475964392	0.42293596	0.13886114	80	4	0.007265976	FALSE	14.01851852	HCK	HCK	135.4358974	15.57700282	0	79	0	0.77259598	FALSE	1	HCK	717020	Infinity	0.03396182
789348	taxon:9606	2.32897432	352.0652878	2.08E-04	175690	1902	apoptosis inducing factor mitochondria associated 1	gene	biological_process-&-1&-GO:0002931-&&-response to ischemia-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1904045-&&-cellular response to aldosterone-%%-GO:1902510-&&-regulation of apoptotic DNA fragmentation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0009636-&&-response to toxic substance-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090650-&&-cellular response to oxygen-glucose deprivation-%%-GO:1902065-&&-response to L-glutamate-%%-GO:0030261-&&-chromosome condensation-%%-GO:0071732-&&-cellular response to nitric oxide|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0071949-&&-FAD binding-%%-GO:0016651-&&-oxidoreductase activity, acting on NAD(P)H-%%-GO:0016174-&&-NAD(P)H oxidase activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:AIFM1			KEGG-&-1&-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis	AIFM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIFM1	0.492931776	0.42937356	0.06959707	80	4	0.014765697	FALSE	8.946428571	AIFM1	AIFM1	209.4615385	9.186021587	0	79	0	0.77850428	FALSE	1	AIFM1	473174	Infinity	0.04982975
789490	taxon:9606	2.51173783	490.9827455	2.03E-04	175349	1902	mortality factor 4 like 2	gene	biological_process-&-1&-GO:0043967-&&-histone H4 acetylation-%%-GO:0040008-&&-regulation of growth-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0016575-&&-histone deacetylation-%%-GO:0051155-&&-positive regulation of striated muscle cell differentiation-%%-GO:0006281-&&-DNA repair-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MORF4L2				MORF4L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MORF4L2	0.473295958	0.39813072	0.11360759	80	4	0.009812407	FALSE	8.055555556	MORF4L2	MORF4L2	125.6375	8.50874258	0	80	0	0.7480437	FALSE	0	MORF4L2	324294	Infinity	0.04093984
789606	taxon:9606	2.40491571	539.3877453	3.33E-04	175078	1902	WD repeat domain 1	gene	biological_process-&-1&-GO:0042247-&&-establishment of planar polarity of follicular epithelium-%%-GO:1990266-&&-neutrophil migration-%%-GO:0030043-&&-actin filament fragmentation-%%-GO:0030865-&&-cortical cytoskeleton organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0030220-&&-platelet formation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0045214-&&-sarcomere organization-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0040011-&&-locomotion-%%-GO:0030834-&&-regulation of actin filament depolymerization-%%-GO:0045199-&&-maintenance of epithelial cell apical/basal polarity-%%-GO:0043297-&&-apical junction assembly-%%-GO:0030836-&&-positive regulation of actin filament depolymerization-%%-GO:0048713-&&-regulation of oligodendrocyte differentiation|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0002102-&&-podosome-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0042643-&&-actomyosin, actin portion-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0051015-&&-actin filament binding	G:9606:WDR1				WDR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR1	0.484299517	0.41581499	0.12056962	80	4	0.009221103	FALSE	10.94339623	WDR1	WDR1	137.4875	11.55713069	0	80	0	0.76584738	FALSE	0	WDR1	459906	Infinity	0.03694235
790210	taxon:9606	2.39829841	373.8309494	2.75E-04	173635	1902	erythrocyte membrane protein band 4.1 like 3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0002175-&&-protein localization to paranode region of axon-%%-GO:0030865-&&-cortical cytoskeleton organization-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0030913-&&-paranodal junction assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0071205-&&-protein localization to juxtaparanode region of axon-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0008150-&&-biological_process-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0043217-&&-myelin maintenance-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030673-&&-axolemma-%%-GO:0033270-&&-paranode region of axon-%%-GO:0005829-&&-cytosol-%%-GO:0044224-&&-juxtaparanode region of axon|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:EPB41L3				EPB41L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41L3	0.487241798	0.41696229	0.1085443	80	4	0.011113025	FALSE	10.73076923	EPB41L3	EPB41L3	147.1875	11.06054001	0	80	0	0.76695027	FALSE	0	EPB41L3	397794	Infinity	0.03901816
790419	taxon:9606	2.40412793	944.256366	2.68E-04	173049	1902	FK506 binding protein 8	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006915-&&-apoptotic process-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0016032-&&-viral process-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0043010-&&-camera-type eye development-%%-GO:0001708-&&-cell fate specification-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0046872-&&-metal ion binding	G:9606:FKBP8				FKBP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP8	0.479235136	0.41595124	0.19014319	80	4	0.008781153	FALSE	20.18333333	FKBP8	FKBP8	139.3717949	21.1382734	0	79	0	0.76597868	FALSE	1	FKBP8	401692	Infinity	0.03729136
790598	taxon:9606	2.30943753	546.7108747	3.04E-04	172001	1902	argonaute 2, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0006412-&&-translation-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0006413-&&-translational initiation-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035087-&&-siRNA loading onto RISC involved in RNA interference-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0010586-&&-miRNA metabolic process-%%-GO:1905618-&&-positive regulation of miRNA mediated inhibition of translation-%%-GO:0009791-&&-post-embryonic development-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0045947-&&-negative regulation of translational initiation|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0035068-&&-micro-ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0005844-&&-polysome-%%-GO:0030425-&&-dendrite-%%-GO:0005845-&&-mRNA cap binding complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0035197-&&-siRNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0090624-&&-endoribonuclease activity, cleaving miRNA-paired mRNA-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0070551-&&-endoribonuclease activity, cleaving siRNA-paired mRNA-%%-GO:0001047-&&-core promoter binding-%%-GO:0098808-&&-mRNA cap binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:AGO2				AGO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO2	0.495061728	0.43300587	0.11262577	79	4	0.013635313	FALSE	9.574074074	AGO2	AGO2	191.3417722	10.19859439	0	79	0	0.78176041	FALSE	0	AGO2	493302	Infinity	0.04421165
790766	taxon:9606	2.49771546	398.0784616	1.79E-04	171291	1902	ninein	gene	biological_process-&-1&-GO:0051642-&&-centrosome localization-%%-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0090222-&&-centrosome-templated microtubule nucleation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0097539-&&-ciliary transition fiber-%%-GO:0005814-&&-centriole-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0036449-&&-microtubule minus-end-%%-GO:0000922-&&-spindle pole-%%-GO:0097431-&&-mitotic spindle pole|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NIN				NIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NIN	0.460654796	0.40036586	0.10184552	79	4	0.004949092	FALSE	9.318181818	NIN	NIN	97.76623377	9.569879166	0	78	0	0.75038076	FALSE	1	NIN	260868	Infinity	0.03079146
787736	taxon:9606	2.3812825	415.5624778	1.96E-04	178858	1902	RNA polymerase II subunit E	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0010467-&&-gene expression-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0016032-&&-viral process-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005666-&&-DNA-directed RNA polymerase III complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005736-&&-DNA-directed RNA polymerase I complex|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001056-&&-RNA polymerase III activity-%%-GO:0005515-&&-protein binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0001054-&&-RNA polymerase I activity	G:9606:POLR2E			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05016-&&-Huntington disease	POLR2E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2E	0.492780338	0.41994178	0.183527	79	4	0.013285678	FALSE	14.21568627	POLR2E	POLR2E	183.3116883	15.24670358	0	78	0	0.76978625	FALSE	1	POLR2E	381004	Infinity	0.04724407
787729	taxon:9606	2.32850165	457.1399512	2.19E-04	178861	1902	RNA polymerase II subunit B	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032549-&&-ribonucleoside binding-%%-GO:0046872-&&-metal ion binding	G:9606:POLR2B			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2B	0.495367511	0.42946072	0.16098669	79	4	0.012630753	FALSE	10.67307692	POLR2B	POLR2B	188.8607595	11.52908101	0	79	0	0.77858306	FALSE	0	POLR2B	428706	Infinity	0.04478557
787730	taxon:9606	2.40318261	533.7251581	1.90E-04	178860	1902	RNA polymerase II subunit C	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding	G:9606:POLR2C			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2C	0.487241798	0.41611486	0.15755297	79	4	0.010189525	FALSE	11.3877551	POLR2C	POLR2C	147.5584416	12.3177131	0	78	0	0.76613623	FALSE	1	POLR2C	348306	Infinity	0.03941916
791892	taxon:9606	2.32692611	323.2004961	2.23E-04	182916	1902	adaptor related protein complex 2 alpha 1 subunit	gene	biological_process-&-1&-GO:0006895-&&-Golgi to endosome transport-%%-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1900126-&&-negative regulation of hyaluronan biosynthetic process-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006897-&&-endocytosis-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0032433-&&-filopodium tip-%%-GO:0005829-&&-cytosol-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0036020-&&-endolysosome membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0035615-&&-clathrin adaptor activity	G:9606:AP2A1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2A1	0.495367511	0.42975151	0.19376826	79	4	0.013013791	FALSE	16.48148148	AP2A1	AP2A1	200.4303798	17.24466019	0	79	0	0.77884565	FALSE	0	AP2A1	432774	Infinity	0.04760516
792006	taxon:9606	2.30329289	418.828687	2.44E-04	182742	1902	BCR, RhoGEF and GTPase activating protein	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0060268-&&-negative regulation of respiratory burst-%%-GO:0043314-&&-negative regulation of neutrophil degranulation-%%-GO:0051171-&&-regulation of nitrogen compound metabolic process-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0003014-&&-renal system process-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060313-&&-negative regulation of blood vessel remodeling-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0002692-&&-negative regulation of cellular extravasation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0065002-&&-intracellular protein transmembrane transport-%%-GO:0007165-&&-signal transduction-%%-GO:0007420-&&-brain development-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0050885-&&-neuromuscular process controlling balance|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030054-&&-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005524-&&-ATP binding	G:9606:BCR			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	BCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCR	0.497827436	0.43416102	0.16267943	79	4	0.010991179	FALSE	16.16071429	BCR	BCR	190.0909091	16.82167155	0	78	0	0.78278452	FALSE	1	BCR	422110	Infinity	0.04354294
788376	taxon:9606	2.38096739	575.4344387	1.75E-04	177780	1902	single stranded DNA binding protein 1	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0070584-&&-mitochondrion morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:SSBP1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03440-&&-Homologous recombination-%%-hsa03030-&&-DNA replication	SSBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSBP1	0.491421569	0.41999735	0.13602187	79	4	0.018022532	FALSE	13.96666667	SSBP1	SSBP1	216.1168831	14.58424416	0	78	0	0.76983877	FALSE	1	SSBP1	379934	Infinity	0.0555899
788494	taxon:9606	2.33433118	393.0874149	1.24E-04	177554	1902	small nuclear ribonucleoprotein polypeptide A	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1900363-&&-regulation of mRNA polyadenylation|cellular_component-&-1&-GO:0005685-&&-U1 snRNP-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030619-&&-U1 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035614-&&-snRNA stem-loop binding-%%-GO:1990446-&&-U1 snRNP binding	G:9606:SNRPA			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPA	0.498911353	0.42838823	0.22932331	79	4	0.020878101	FALSE	21.01515152	SNRPA	SNRPA	243.1298701	21.73718073	0	78	0	0.77761147	FALSE	1	SNRPA	261538	Infinity	0.05832315
788674	taxon:9606	2.41247834	518.1330396	5.64E-04	177216	1902	tight junction protein 1	gene	biological_process-&-1&-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0035329-&&-hippo signaling-%%-GO:1901350-&&-cell-cell signaling involved in cell-cell junction organization-%%-GO:0007043-&&-cell-cell junction assembly|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005921-&&-gap junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043296-&&-apical junction complex-%%-GO:0045177-&&-apical part of cell-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding	G:9606:TJP1	TJP1	TRUE	KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05132-&&-Salmonella infection-%%-hsa04530-&&-Tight junction-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection	TJP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TJP1	0.482260974	0.41451149	0.07758031	79	4	0.009306835	FALSE	9.145833333	TJP1	TJP1	148.7532468	9.494086249	0	78	0	0.76458694	FALSE	1	TJP1	702100	Infinity	0.04043347
788716	taxon:9606	2.35890972	502.4921342	1.02E-04	177129	1902	translocated promoter region, nuclear basket protein	gene	biological_process-&-1&-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0090267-&&-positive regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0070849-&&-response to epidermal growth factor-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0010965-&&-regulation of mitotic sister chromatid separation-%%-GO:0045947-&&-negative regulation of translational initiation-%%-GO:0006404-&&-RNA import into nucleus-%%-GO:0031453-&&-positive regulation of heterochromatin assembly-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0008150-&&-biological_process-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0046832-&&-negative regulation of RNA export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0000189-&&-MAPK import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0006999-&&-nuclear pore organization-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0034605-&&-cellular response to heat-%%-GO:0035457-&&-cellular response to interferon-alpha-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0010793-&&-regulation of mRNA export from nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0043578-&&-nuclear matrix organization-%%-GO:0031990-&&-mRNA export from nucleus in response to heat stress-%%-GO:0016032-&&-viral process-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0042306-&&-regulation of protein import into nucleus|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000776-&&-kinetochore-%%-GO:0005737-&&-cytoplasm-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005635-&&-nuclear envelope-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043495-&&-protein anchor-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0005215-&&-transporter activity-%%-GO:0003674-&&-molecular_function-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0015631-&&-tubulin binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:TPR			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	TPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPR	0.497056089	0.42392466	0.17624148	79	4	0.018727699	FALSE	15.07246377	TPR	TPR	215	15.68015159	0	79	0	0.77351505	FALSE	0	TPR	245352	Infinity	0.05362302
788710	taxon:9606	2.31447928	402.5344391	4.91E-04	177137	1902	triosephosphate isomerase 1	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0019563-&&-glycerol catabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0046166-&&-glyceraldehyde-3-phosphate biosynthetic process-%%-GO:0006096-&&-glycolytic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004807-&&-triose-phosphate isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TPI1			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00562-&&-Inositol phosphate metabolism	TPI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPI1	0.494146642	0.43206263	0.14559125	79	4	0.014044163	FALSE	14.52830189	TPI1	TPI1	202.0909091	15.0837228	0	78	0	0.78092012	FALSE	1	TPI1	720268	Infinity	0.04694817
789164	taxon:9606	2.55916181	385.4943563	3.53E-04	176067	1902	unc-119 lipid binding chaperone	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006897-&&-endocytosis-%%-GO:0007602-&&-phototransduction-%%-GO:1900186-&&-negative regulation of clathrin-dependent endocytosis-%%-GO:2001287-&&-negative regulation of caveolin-mediated endocytosis-%%-GO:0042953-&&-lipoprotein transport|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0051233-&&-spindle midzone-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008289-&&-lipid binding-%%-GO:0005515-&&-protein binding	G:9606:UNC119				UNC119	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNC119	0.451576577	0.39075294	0.01914963	79	4	0.004319709	FALSE	2.361111111	UNC119	UNC119	75.84810127	2.464018335	0	79	0	0.7401397	FALSE	0	UNC119	393996	Infinity	0.02767741
789228	taxon:9606	2.30959508	527.0099966	1.48E-04	175962	1902	KH-type splicing regulatory protein	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:2000628-&&-regulation of miRNA metabolic process-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0008380-&&-RNA splicing-%%-GO:0061014-&&-positive regulation of mRNA catabolic process|cellular_component-&-1&-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010494-&&-cytoplasmic stress granule|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:KHSRP				KHSRP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KHSRP	0.499221911	0.43297633	0.1415125	79	4	0.020908128	FALSE	12.09230769	KHSRP	KHSRP	258.6962025	12.65353242	0	79	0	0.78173415	FALSE	0	KHSRP	392354	Infinity	0.0599381
793353	taxon:9606	2.41421144	309.5188896	2.74E-04	180248	1902	hepatocyte nuclear factor 4 alpha	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006591-&&-ornithine metabolic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:2000189-&&-positive regulation of cholesterol homeostasis-%%-GO:0010470-&&-regulation of gastrulation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0055091-&&-phospholipid homeostasis-%%-GO:0007548-&&-sex differentiation-%%-GO:0009749-&&-response to glucose-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005102-&&-receptor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:HNF4A			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04950-&&-Maturity onset diabetes of the young	HNF4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNF4A	0.477380952	0.41421393	0.14935065	79	4	0.008733313	FALSE	14.95918367	HNF4A	HNF4A	144.038961	15.7862229	0	78	0	0.76429809	FALSE	1	HNF4A	370972	Infinity	0.03915524
789481	taxon:9606	2.48180243	449.3725275	3.56E-04	175370	1902	TNF receptor associated factor 4	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030323-&&-respiratory tube development-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0050699-&&-WW domain binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TRAF4			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	TRAF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF4	0.473715298	0.40293296	0.06151743	79	5	0.006329488	FALSE	6.953488372	TRAF4	TRAF4	106.6623377	7.177802555	0	78	0	0.75303293	FALSE	1	TRAF4	474360	Infinity	0.03292906
789603	taxon:9606	2.44666772	211.6364797	3.24E-04	175086	1902	RNA binding motif protein 8A	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding	G:9606:RBM8A	RBM8A	TRUE	KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	RBM8A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM8A	0.480239521	0.40871917	0.10423787	79	4	0.011529105	FALSE	12.87234043	RBM8A	RBM8A	136.2857143	13.17826087	0	78	0	0.75888871	FALSE	1	RBM8A	465604	Infinity	0.03937792
790007	taxon:9606	2.44351662	273.5136435	1.27E-04	174126	1902	zinc finger and BTB domain containing 1	gene	biological_process-&-1&-GO:2000176-&&-positive regulation of pro-T cell differentiation-%%-GO:0045087-&&-innate immune response-%%-GO:0002711-&&-positive regulation of T cell mediated immunity-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0048538-&&-thymus development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0030183-&&-B cell differentiation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032825-&&-positive regulation of natural killer cell differentiation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZBTB1				ZBTB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB1	0.486945962	0.40924624	0.14410906	79	4	0.018378662	FALSE	13.46153846	ZBTB1	ZBTB1	157.6329114	13.70332818	0	79	0	0.7594139	FALSE	0	ZBTB1	220062	Infinity	0.04513233
790059	taxon:9606	2.40475815	426.5338155	1.42E-04	173982	1902	lysine acetyltransferase 7	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0043983-&&-histone H4-K12 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043984-&&-histone H4-K16 acetylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:KAT7				KAT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT7	0.480671262	0.41584223	0.16293411	79	4	0.016093072	FALSE	15.83050847	KAT7	KAT7	206.9367089	16.33895625	0	79	0	0.76587364	FALSE	0	KAT7	361020	Infinity	0.05532052
787263	taxon:9606	2.56152513	535.5904896	2.21E-04	179782	1902	Janus kinase 3	gene	biological_process-&-1&-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0007260-&&-tyrosine phosphorylation of STAT protein-%%-GO:0002731-&&-negative regulation of dendritic cell cytokine production-%%-GO:0070232-&&-regulation of T cell apoptotic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0035771-&&-interleukin-4-mediated signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0071104-&&-response to interleukin-9-%%-GO:0006954-&&-inflammatory response-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045626-&&-negative regulation of T-helper 1 cell differentiation-%%-GO:0050868-&&-negative regulation of T cell activation-%%-GO:0070670-&&-response to interleukin-4-%%-GO:0032693-&&-negative regulation of interleukin-10 production-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045221-&&-negative regulation of FasL biosynthetic process-%%-GO:0070244-&&-negative regulation of thymocyte apoptotic process-%%-GO:0070669-&&-response to interleukin-2-%%-GO:0016477-&&-cell migration-%%-GO:0002250-&&-adaptive immune response-%%-GO:0000165-&&-MAPK cascade-%%-GO:0070672-&&-response to interleukin-15|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0012505-&&-endomembrane system-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding	G:9606:JAK3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	JAK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAK3	0.454133635	0.39039242	0.08175439	78	4	0.006211476	FALSE	8.693877551	JAK3	JAK3	91.38157895	9.258884625	0	77	0	0.73974581	FALSE	1	JAK3	274330	Infinity	0.03337636
792078	taxon:9606	2.60894911	173.7124814	2.11E-04	182655	1902	CLN3, battenin	gene	biological_process-&-1&-GO:0042133-&&-neurotransmitter metabolic process-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0001575-&&-globoside metabolic process-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0061024-&&-membrane organization-%%-GO:0006678-&&-glucosylceramide metabolic process-%%-GO:0016485-&&-protein processing-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0015809-&&-arginine transport-%%-GO:0035752-&&-lysosomal lumen pH elevation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006681-&&-galactosylceramide metabolic process-%%-GO:0006684-&&-sphingomyelin metabolic process-%%-GO:0001508-&&-action potential-%%-GO:0016236-&&-macroautophagy-%%-GO:0007042-&&-lysosomal lumen acidification-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0008306-&&-associative learning-%%-GO:0007040-&&-lysosome organization-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0006520-&&-cellular amino acid metabolic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005795-&&-Golgi stack-%%-GO:0005739-&&-mitochondrion-%%-GO:0005764-&&-lysosome-%%-GO:0005776-&&-autophagosome-%%-GO:0005901-&&-caveola-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005770-&&-late endosome-%%-GO:0043005-&&-neuron projection-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CLN3			KEGG-&-1&-hsa04142-&&-Lysosome	CLN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLN3	0.443461432	0.38329609	0.04395604	78	4	0.004978416	FALSE	3.657142857	CLN3	CLN3	76.01282051	3.764705882	0	78	0	0.73184182	FALSE	0	CLN3	290838	Infinity	0.03111673
792063	taxon:9606	2.53442571	290.8022447	2.85E-04	182669	1902	BUB1 mitotic checkpoint serine/threonine kinase	gene	biological_process-&-1&-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0006915-&&-apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0007063-&&-regulation of sister chromatid cohesion-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051754-&&-meiotic sister chromatid cohesion, centromeric-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0071173-&&-spindle assembly checkpoint-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:BUB1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	BUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB1	0.45361991	0.3945667	0.04421053	78	4	0.004747904	FALSE	6.558823529	BUB1	BUB1	85.64473684	6.928528624	0	77	0	0.74426238	FALSE	1	BUB1	359560	Infinity	0.02933312
788268	taxon:9606	2.36048527	258.1180455	2.89E-04	177968	1902	ribosomal protein S6 kinase A1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007165-&&-signal transduction-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:0043555-&&-regulation of translation in response to stress-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0072574-&&-hepatocyte proliferation-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:RPS6KA1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04720-&&-Long-term potentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04150-&&-mTOR signaling pathway	RPS6KA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA1	0.480383348	0.4236417	0.08701754	78	4	0.008132103	FALSE	9.452380952	RPS6KA1	RPS6KA1	135.3684211	9.713742964	0	77	0	0.77325246	FALSE	1	RPS6KA1	402012	Infinity	0.03379373
792384	taxon:9606	2.44840082	269.2469958	5.57E-05	165731	1902	FtsJ homolog 3	gene	biological_process-&-1&-GO:0031167-&&-rRNA methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008649-&&-rRNA methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:FTSJ3				FTSJ3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FTSJ3	0.484299517	0.40842986	0.28138528	78	4	0.017909097	FALSE	21.27118644	FTSJ3	FTSJ3	190.9102564	21.76433829	0	78	0	0.75859986	FALSE	0	FTSJ3	145380	Infinity	0.05506497
788309	taxon:9606	2.52843863	152.4921725	2.93E-04	177908	1902	sortilin 1	gene	biological_process-&-1&-GO:0032868-&&-response to insulin-%%-GO:0016050-&&-vesicle organization-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0001503-&&-ossification-%%-GO:0006897-&&-endocytosis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0046323-&&-glucose import-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0051005-&&-negative regulation of lipoprotein lipase activity-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0014902-&&-myotube differentiation-%%-GO:0006895-&&-Golgi to endosome transport-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0007275-&&-multicellular organism development-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:1904037-&&-positive regulation of epithelial cell apoptotic process-%%-GO:0032509-&&-endosome transport via multivesicular body sorting pathway|cellular_component-&-1&-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0010008-&&-endosome membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0043025-&&-neuronal cell body-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030136-&&-clathrin-coated vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030379-&&-neurotensin receptor activity, non-G-protein coupled-%%-GO:0048406-&&-nerve growth factor binding-%%-GO:0010465-&&-nerve growth factor receptor activity-%%-GO:0019899-&&-enzyme binding	G:9606:SORT1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa04142-&&-Lysosome	SORT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SORT1	0.454777431	0.395501	0.02997003	78	4	0.004846707	FALSE	3.730769231	SORT1	SORT1	79.32051282	3.88	0	78	0	0.74526023	FALSE	0	SORT1	319458	Infinity	0.02686908
788528	taxon:9606	2.48416575	381.4417623	2.22E-04	177497	1902	thyroid hormone receptor, alpha	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0017055-&&-negative regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007611-&&-learning or memory-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0008050-&&-female courtship behavior-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0050994-&&-regulation of lipid catabolic process-%%-GO:2000143-&&-negative regulation of DNA-templated transcription, initiation-%%-GO:0030878-&&-thyroid gland development-%%-GO:0001503-&&-ossification-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0033032-&&-regulation of myeloid cell apoptotic process-%%-GO:0045925-&&-positive regulation of female receptivity-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0002155-&&-regulation of thyroid hormone mediated signaling pathway-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0001502-&&-cartilage condensation-%%-GO:0060509-&&-Type I pneumocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0002153-&&-steroid receptor RNA activator RNA binding-%%-GO:0070324-&&-thyroid hormone binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:THRA			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	THRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRA	0.471764706	0.40254963	0.11894737	78	4	0.008957449	FALSE	12	THRA	THRA	128.1973684	12.44068071	0	77	0	0.75263904	FALSE	1	THRA	324828	Infinity	0.03962422
792664	taxon:9606	2.38506381	449.2531259	2.21E-04	181596	1902	DAB2, clathrin adaptor protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0061024-&&-membrane organization-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0015031-&&-protein transport-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:2000370-&&-positive regulation of clathrin-dependent endocytosis-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0035026-&&-leading edge cell differentiation-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045807-&&-positive regulation of endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070022-&&-transforming growth factor beta receptor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0038024-&&-cargo receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:DAB2			KEGG-&-1&-hsa04144-&&-Endocytosis	DAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAB2	0.48009578	0.41927599	0.12820513	78	4	0.008955333	FALSE	11.7962963	DAB2	DAB2	147.7820513	12.45751645	0	78	0	0.76915603	FALSE	0	DAB2	366008	Infinity	0.03855187
793066	taxon:9606	2.38742713	564.5461037	1.27E-04	180814	1902	mutS homolog 6	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0006298-&&-mismatch repair-%%-GO:0045190-&&-isotype switching-%%-GO:0000710-&&-meiotic mismatch repair-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016447-&&-somatic recombination of immunoglobulin gene segments-%%-GO:0006281-&&-DNA repair-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0009411-&&-response to UV-%%-GO:0016032-&&-viral process-%%-GO:0045830-&&-positive regulation of isotype switching-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0032301-&&-MutSalpha complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0032143-&&-single thymine insertion binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0043531-&&-ADP binding-%%-GO:0032137-&&-guanine/thymine mispair binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0032142-&&-single guanine insertion binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:MSH6	MSH6	TRUE	KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance	MSH6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSH6	0.491722869	0.41886095	0.15084915	78	4	0.012445249	FALSE	12.85245902	MSH6	MSH6	174.0128205	13.49547306	0	78	0	0.76876214	FALSE	0	MSH6	282818	Infinity	0.04523005
789005	taxon:9606	2.44587994	667.5381744	9.09E-05	176409	1902	acidic nuclear phosphoprotein 32 family member A	gene	biological_process-&-1&-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ANP32A				ANP32A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANP32A	0.485619134	0.40885081	0.18614719	78	4	0.017312003	FALSE	15.50746269	ANP32A	ANP32A	200.3333333	15.98649298	0	78	0	0.75902001	FALSE	0	ANP32A	246276	Infinity	0.05747342
789099	taxon:9606	2.35386797	131.6283895	9.94E-05	176198	1902	DEAD-box helicase 18	gene	biological_process-&-1&-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:DDX18				DDX18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX18	0.491873658	0.42483266	0.32667333	78	4	0.021180149	FALSE	26.72881356	DDX18	DDX18	228.0512821	27.41901567	0	78	0	0.77435534	FALSE	0	DDX18	213022	Infinity	0.05641723
789847	taxon:9606	2.54277611	166.5827476	9.94E-05	174516	1902	chromobox 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0001939-&&-female pronucleus-%%-GO:0005819-&&-spindle-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001940-&&-male pronucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0010369-&&-chromocenter-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:1990226-&&-histone methyltransferase binding	G:9606:CBX1				CBX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX1	0.467502186	0.39327096	0.30666667	78	4	0.017512733	FALSE	28.56451613	CBX1	CBX1	193.8289474	29.25273877	0	77	0	0.74287065	FALSE	1	CBX1	219706	Infinity	0.06696705
790359	taxon:9606	2.41232078	352.9240458	1.50E-04	173221	1902	Ski2 like RNA helicase 2	gene	biological_process-&-1&-GO:0006401-&&-RNA catabolic process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:SKIV2L2			KEGG-&-1&-hsa03018-&&-RNA degradation	SKIV2L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKIV2L2	0.488280061	0.41453857	0.15384615	78	4	0.015359674	FALSE	13.18181818	SKIV2L2	SKIV2L2	194.9358974	13.7024629	0	78	0	0.7646132	FALSE	0	SKIV2L2	287156	Infinity	0.05265691
790383	taxon:9606	2.40018907	626.2658868	2.12E-04	173156	1902	coronin 1C	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0006909-&&-phagocytosis-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:1900024-&&-regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0016600-&&-flotillin complex-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0048365-&&-Rac GTPase binding	G:9606:CORO1C				CORO1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CORO1C	0.489920586	0.41663385	0.13220113	78	4	0.011835607	FALSE	12	CORO1C	CORO1C	162.5769231	12.64460247	0	78	0	0.76663516	FALSE	0	CORO1C	358206	Infinity	0.0433239
790685	taxon:9606	2.54624232	345.7722707	9.58E-05	171476	1902	bromodomain containing 7	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0090544-&&-BAF-type complex|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042393-&&-histone binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding	G:9606:BRD7			KEGG-&-1&-hsa05225-&&-Hepatocellular carcinoma	BRD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD7	0.46025825	0.3927356	0.20198223	77	4	0.014955653	FALSE	16.89285714	BRD7	BRD7	179.1298701	17.35661407	0	77	0	0.74229295	FALSE	0	BRD7	242120	Infinity	0.06237023
791959	taxon:9606	2.29888136	746.8219618	3.54E-04	182804	1902	annexin A1	gene	biological_process-&-1&-GO:0044849-&&-estrous cycle-%%-GO:0042063-&&-gliogenesis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0031394-&&-positive regulation of prostaglandin biosynthetic process-%%-GO:0071621-&&-granulocyte chemotaxis-%%-GO:0036292-&&-DNA rewinding-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0045629-&&-negative regulation of T-helper 2 cell differentiation-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0045920-&&-negative regulation of exocytosis-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0030850-&&-prostate gland development-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0045627-&&-positive regulation of T-helper 1 cell differentiation-%%-GO:1900138-&&-negative regulation of phospholipase A2 activity-%%-GO:2000483-&&-negative regulation of interleukin-8 secretion-%%-GO:0001780-&&-neutrophil homeostasis-%%-GO:0014839-&&-myoblast migration involved in skeletal muscle regeneration-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0046883-&&-regulation of hormone secretion-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0033031-&&-positive regulation of neutrophil apoptotic process-%%-GO:0006909-&&-phagocytosis-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0032355-&&-response to estradiol-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0006954-&&-inflammatory response-%%-GO:0002685-&&-regulation of leukocyte migration-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0010165-&&-response to X-ray-%%-GO:0032652-&&-regulation of interleukin-1 production-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0045087-&&-innate immune response-%%-GO:0030073-&&-insulin secretion-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0097350-&&-neutrophil clearance-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0070459-&&-prolactin secretion-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0031514-&&-motile cilium-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0001533-&&-cornified envelope-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0031313-&&-extrinsic component of endosome membrane-%%-GO:0043234-&&-protein complex-%%-GO:0042383-&&-sarcolemma-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001891-&&-phagocytic cup-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0042629-&&-mast cell granule-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0019834-&&-phospholipase A2 inhibitor activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005102-&&-receptor binding-%%-GO:0036310-&&-annealing helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0005198-&&-structural molecule activity-%%-GO:0033676-&&-double-stranded DNA-dependent ATPase activity	G:9606:ANXA1				ANXA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA1	0.498601181	0.43499417	0.08475735	77	4	0.014369768	FALSE	8.166666667	ANXA1	ANXA1	201.3246753	8.510965037	0	77	0	0.78351977	FALSE	0	ANXA1	542522	Infinity	0.04587501
791981	taxon:9606	2.30738932	458.3135473	1.61E-04	182778	1902	apurinic/apyrimidinic endodeoxyribonuclease 1	gene	biological_process-&-1&-GO:0006286-&&-base-excision repair, base-free sugar-phosphate removal-%%-GO:0006284-&&-base-excision repair-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006310-&&-DNA recombination-%%-GO:0000723-&&-telomere maintenance-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0080111-&&-DNA demethylation-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0007568-&&-aging-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005840-&&-ribosome-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0004528-&&-phosphodiesterase I activity-%%-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0004519-&&-endonuclease activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0016890-&&-site-specific endodeoxyribonuclease activity, specific for altered base-%%-GO:0005515-&&-protein binding-%%-GO:0004523-&&-RNA-DNA hybrid ribonuclease activity-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004520-&&-endodeoxyribonuclease activity-%%-GO:0004844-&&-uracil DNA N-glycosylase activity-%%-GO:0008081-&&-phosphoric diester hydrolase activity-%%-GO:0008309-&&-double-stranded DNA exodeoxyribonuclease activity-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008311-&&-double-stranded DNA 3'-5' exodeoxyribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:APEX1			KEGG-&-1&-hsa03410-&&-Base excision repair	APEX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APEX1	0.499532856	0.43339024	0.12720721	77	4	0.014485613	FALSE	12.93442623	APEX1	APEX1	203.9866667	13.50809998	0	76	0	0.78210178	FALSE	1	APEX1	332912	Infinity	0.04693517
792311	taxon:9606	2.61336064	332.7733071	8.58E-05	165863	1902	forkhead box Q1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:FOXQ1				FOXQ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXQ1	0.440659341	0.38264906	0.03485988	77	4	0.006085757	FALSE	3.390243902	FOXQ1	FOXQ1	80.67532468	3.489473608	0	77	0	0.73110656	FALSE	0	FOXQ1	153350	Infinity	0.0328976
788314	taxon:9606	2.40239483	466.5419923	1.33E-04	177900	1902	S100 calcium binding protein A9	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0032119-&&-sequestering of zinc ion-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0050832-&&-defense response to fungus-%%-GO:0002793-&&-positive regulation of peptide secretion-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006914-&&-autophagy-%%-GO:0006954-&&-inflammatory response-%%-GO:0070488-&&-neutrophil aggregation-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0001816-&&-cytokine production-%%-GO:0006417-&&-regulation of translation-%%-GO:0045113-&&-regulation of integrin biosynthetic process-%%-GO:0035606-&&-peptidyl-cysteine S-trans-nitrosylation-%%-GO:0032602-&&-chemokine production-%%-GO:0014002-&&-astrocyte development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0035662-&&-Toll-like receptor 4 binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016209-&&-antioxidant activity-%%-GO:0050544-&&-arachidonic acid binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0004871-&&-signal transducer activity	G:9606:S100A9			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	S100A9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A9	0.485619134	0.41625131	0.15891892	77	4	0.014298465	FALSE	15.21311475	S100A9	S100A9	172.8533333	15.69643255	0	76	0	0.76626753	FALSE	1	S100A9	265562	Infinity	0.0462315
792562	taxon:9606	2.32582322	775.7661122	2.88E-04	181808	1902	serpin family H member 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0003433-&&-chondrocyte development involved in endochondral bone morphogenesis-%%-GO:0051604-&&-protein maturation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0032964-&&-collagen biosynthetic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005615-&&-extracellular space-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0003723-&&-RNA binding	G:9606:SERPINH1				SERPINH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINH1	0.495061728	0.42995529	0.08065619	77	4	0.012529919	FALSE	7.196428571	SERPINH1	SERPINH1	190.1428571	7.5488488	0	77	0	0.77902946	FALSE	0	SERPINH1	534082	Infinity	0.04503149
792692	taxon:9606	2.40255239	500.4933434	2.07E-04	181553	1902	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	gene	biological_process-&-1&-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0034097-&&-response to cytokine-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006486-&&-protein glycosylation-%%-GO:0042110-&&-T cell activation-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine|cellular_component-&-1&-GO:0035577-&&-azurophil granule membrane-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004576-&&-oligosaccharyl transferase activity	G:9606:DDOST			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DDOST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDOST	0.481103779	0.41622401	0.16507177	77	4	0.011333625	FALSE	12.81481481	DDOST	DDOST	160.8701299	13.72564404	0	77	0	0.76624127	FALSE	0	DDOST	346236	Infinity	0.04305946
788745	taxon:9606	2.32393257	403.4298621	1.56E-04	177050	1902	DnaJ heat shock protein family (Hsp40) member C7	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:DNAJC7				DNAJC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC7	0.499844188	0.43030508	0.14774775	77	4	0.013365929	FALSE	14.61403509	DNAJC7	DNAJC7	190.52	15.401247	0	76	0	0.77934457	FALSE	1	DNAJC7	315576	Infinity	0.04493198
788790	taxon:9606	2.46951316	473.0503797	5.40E-05	176885	1902	DEK proto-oncogene	gene	biological_process-&-1&-GO:2001032-&&-regulation of double-strand break repair via nonhomologous end joining-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0019079-&&-viral genome replication-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007165-&&-signal transduction-%%-GO:2000779-&&-regulation of double-strand break repair-%%-GO:0006338-&&-chromatin remodeling|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043292-&&-contractile fiber-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042393-&&-histone binding	G:9606:DEK				DEK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEK	0.48313253	0.40493811	0.29369369	77	4	0.021316346	FALSE	24.80555556	DEK	DEK	237.48	25.62116987	0	76	0	0.75508114	FALSE	1	DEK	166866	Infinity	0.07129391
788971	taxon:9606	2.52260911	293.4718009	1.30E-04	176506	1902	CCHC-type zinc finger nucleic acid binding protein	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006695-&&-cholesterol biosynthetic process|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding	G:9606:CNBP	CNBP	TRUE		CNBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNBP	0.469830111	0.39641496	0.15789474	77	4	0.018432209	FALSE	14.6779661	CNBP	CNBP	183.4025974	15.01545743	0	77	0	0.74623182	FALSE	0	CNBP	263460	Infinity	0.06092545
789161	taxon:9606	2.29289428	858.5305294	2.86E-04	176068	1902	DnaJ heat shock protein family (Hsp40) member A3	gene	biological_process-&-1&-GO:0007005-&&-mitochondrion organization-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0006457-&&-protein folding-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0009408-&&-response to heat-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0007569-&&-cell aging-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0006264-&&-mitochondrial DNA replication|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005884-&&-actin filament-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:DNAJA3			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis	DNAJA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA3	0.499066584	0.43613001	0.11483254	77	4	0.012983331	FALSE	10.578125	DNAJA3	DNAJA3	200.4155844	11.08566199	0	77	0	0.78451762	FALSE	0	DNAJA3	490260	Infinity	0.04528285
793327	taxon:9606	2.42634315	283.5157891	2.80E-04	180315	1902	ubiquitin conjugating enzyme E2 K	gene	biological_process-&-1&-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0032433-&&-filopodium tip-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:UBE2K			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2K	0.481971154	0.41214286	0.10378378	77	4	0.008568342	FALSE	11.02222222	UBE2K	UBE2K	140.52	11.35810262	0	76	0	0.76227614	FALSE	1	UBE2K	402774	Infinity	0.0389536
793357	taxon:9606	2.33622184	264.7387333	1.53E-04	180241	1902	heterogeneous nuclear ribonucleoprotein A/B	gene	biological_process-&-1&-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPAB				HNRNPAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPAB	0.500780518	0.42804154	0.24846206	77	4	0.023212453	FALSE	22	HNRNPAB	HNRNPAB	268.2077922	22.60068894	0	77	0	0.77729636	FALSE	0	HNRNPAB	306934	Infinity	0.06451643
790065	taxon:9606	2.40334016	784.6199789	4.80E-04	173966	1902	ER lipid raft associated 2	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0045541-&&-negative regulation of cholesterol biosynthetic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0032933-&&-SREBP signaling pathway-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0015485-&&-cholesterol binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:ERLIN2				ERLIN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERLIN2	0.484299517	0.41608758	0.08544087	77	4	0.008947197	FALSE	7.326923077	ERLIN2	ERLIN2	137.7532468	7.752744728	0	77	0	0.76610997	FALSE	0	ERLIN2	629928	Infinity	0.03695338
790575	taxon:9606	2.33307074	372.0997833	1.29E-04	172094	1902	staphylococcal nuclease and tudor domain containing 1	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome-%%-GO:0097433-&&-dense body-%%-GO:0016442-&&-RISC complex|molecular_function-&-1&-GO:0004518-&&-nuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0003723-&&-RNA binding	G:9606:SND1			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis	SND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SND1	0.496902107	0.42861967	0.26280702	76	4	0.023297595	FALSE	22.68253968	SND1	SND1	255.6973684	23.23196704	0	76	0	0.77782154	FALSE	0	SND1	289488	Infinity	0.06123858
790999	taxon:9606	2.67102568	138.013719	3.03E-04	170459	1902	protein arginine methyltransferase 6	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0034970-&&-histone H3-R2 methylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016049-&&-cell growth-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0090398-&&-cellular senescence-%%-GO:0016571-&&-histone methylation-%%-GO:0043985-&&-histone H4-R3 methylation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0070611-&&-histone methyltransferase activity (H3-R2 specific)-%%-GO:0042393-&&-histone binding-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0070612-&&-histone methyltransferase activity (H2A-R3 specific)-%%-GO:0035241-&&-protein-arginine omega-N monomethyltransferase activity	G:9606:PRMT6				PRMT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT6	0.419127254	0.37438801	0.01298246	76	4	0.007745058	FALSE	1.485714286	PRMT6	PRMT6	90.52631579	1.53125	0	76	0	0.72149572	FALSE	0	PRMT6	434612	Infinity	0.04341788
791160	taxon:9606	2.42996691	392.4137873	4.33E-04	169857	1902	NPL4 homolog, ubiquitin recognition factor	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0007030-&&-Golgi organization-%%-GO:0070987-&&-error-free translesion synthesis|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036501-&&-UFD1-NPL4 complex-%%-GO:0042175-&&-nuclear outer membrane-endoplasmic reticulum membrane network-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NPLOC4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	NPLOC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPLOC4	0.482260974	0.41152824	0.10175439	76	4	0.008820627	FALSE	8.955555556	NPLOC4	NPLOC4	130.75	9.249121418	0	76	0	0.76167218	FALSE	0	NPLOC4	556278	Infinity	0.03661359
787186	taxon:9606	2.3979833	480.0030277	1.69E-04	179905	1902	SMAD family member 7	gene	biological_process-&-1&-GO:0034333-&&-adherens junction assembly-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:0022409-&&-positive regulation of cell-cell adhesion-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060373-&&-regulation of ventricular cardiac muscle cell membrane depolarization-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0001657-&&-ureteric bud development-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0030336-&&-negative regulation of cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016342-&&-catenin complex|molecular_function-&-1&-GO:0048185-&&-activin binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0005518-&&-collagen binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0030617-&&-transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity	G:9606:SMAD7	SMAD7	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD7	0.483278096	0.41701708	0.1536468	76	4	0.009152731	FALSE	13.67272727	SMAD7	SMAD7	152.8108108	14.45095683	0	75	0	0.76700278	FALSE	1	SMAD7	306122	Infinity	0.04045825
787404	taxon:9606	2.43910509	571.6284042	1.03E-04	179486	1902	nuclear autoantigenic sperm protein	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0043486-&&-histone exchange-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0015031-&&-protein transport-%%-GO:0008283-&&-cell proliferation-%%-GO:0006260-&&-DNA replication-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0033574-&&-response to testosterone-%%-GO:0001824-&&-blastocyst development-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0051879-&&-Hsp90 protein binding	G:9606:NASP				NASP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NASP	0.487537994	0.40998643	0.17333333	76	4	0.017011821	FALSE	15.03125	NASP	NASP	209.381579	15.56811298	0	76	0	0.76014915	FALSE	0	NASP	284958	Infinity	0.05967188
787395	taxon:9606	2.4578541	321.9953877	1.72E-04	179506	1902	myogenic differentiation 1	gene	biological_process-&-1&-GO:0048743-&&-positive regulation of skeletal muscle fiber development-%%-GO:0014904-&&-myotube cell development-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:2000818-&&-negative regulation of myoblast proliferation-%%-GO:0014908-&&-myotube differentiation involved in skeletal muscle regeneration-%%-GO:0043415-&&-positive regulation of skeletal muscle tissue regeneration-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007518-&&-myoblast fate determination-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043503-&&-skeletal muscle fiber adaptation-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0007517-&&-muscle organ development-%%-GO:0042693-&&-muscle cell fate commitment-%%-GO:0007520-&&-myoblast fusion-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0071453-&&-cellular response to oxygen levels-%%-GO:0045663-&&-positive regulation of myoblast differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0030016-&&-myofibril-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:MYOD1				MYOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOD1	0.480671262	0.40685897	0.19029989	76	4	0.013135991	FALSE	18.91071429	MYOD1	MYOD1	182.7702703	19.64381178	0	75	0	0.75702432	FALSE	1	MYOD1	324326	Infinity	0.05358261
787447	taxon:9606	2.63321254	505.9923998	5.50E-05	179416	1902	methyl-CpG binding protein 2	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:2000820-&&-negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0021549-&&-cerebellum development-%%-GO:0051151-&&-negative regulation of smooth muscle cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042551-&&-neuron maturation-%%-GO:0019230-&&-proprioception-%%-GO:0007616-&&-long-term memory-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0046470-&&-phosphatidylcholine metabolic process-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0016571-&&-histone methylation-%%-GO:0006576-&&-cellular biogenic amine metabolic process-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0035176-&&-social behavior-%%-GO:0021591-&&-ventricular system development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032048-&&-cardiolipin metabolic process-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0006020-&&-inositol metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007416-&&-synapse assembly-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0031061-&&-negative regulation of histone methylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009405-&&-pathogenesis-%%-GO:0001964-&&-startle response-%%-GO:0016573-&&-histone acetylation-%%-GO:0002087-&&-regulation of respiratory gaseous exchange by neurological system process-%%-GO:0008542-&&-visual learning-%%-GO:0016358-&&-dendrite development-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0008211-&&-glucocorticoid metabolic process-%%-GO:0009791-&&-post-embryonic development-%%-GO:1900114-&&-positive regulation of histone H3-K9 trimethylation-%%-GO:0008104-&&-protein localization-%%-GO:0001662-&&-behavioral fear response-%%-GO:0001976-&&-neurological system process involved in regulation of systemic arterial blood pressure-%%-GO:0050432-&&-catecholamine secretion-%%-GO:0019233-&&-sensory perception of pain|cellular_component-&-1&-GO:0000792-&&-heterochromatin-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0010385-&&-double-stranded methylated DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0035197-&&-siRNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding	G:9606:MECP2				MECP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MECP2	0.442360728	0.37976426	0.21824561	76	4	0.014975529	FALSE	17.88405797	MECP2	MECP2	172.1578947	18.75267822	0	76	0	0.72779791	FALSE	0	MECP2	162142	Infinity	0.07308079
787541	taxon:9606	2.44446195	268.0992782	2.37E-04	179217	1902	protein phosphatase 2 scaffold subunit Abeta	gene	biological_process-&-1&-GO:0060561-&&-apoptotic process involved in morphogenesis-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PPP2R1B			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R1B	0.470657277	0.40908798	0.10958904	76	4	0.006873642	FALSE	8.697674419	PPP2R1B	PPP2R1B	115.7432432	9.000221313	0	75	0	0.75925634	FALSE	1	PPP2R1B	320850	Infinity	0.03322315
791706	taxon:9606	2.62691035	143.1671541	2.75E-04	167284	1902	dystrobrevin binding protein 1	gene	biological_process-&-1&-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0032438-&&-melanosome organization-%%-GO:0001956-&&-positive regulation of neurotransmitter secretion-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway-%%-GO:0007596-&&-blood coagulation-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0031175-&&-neuron projection development-%%-GO:0043506-&&-regulation of JUN kinase activity-%%-GO:0060155-&&-platelet dense granule organization-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport|cellular_component-&-1&-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0030424-&&-axon-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0016528-&&-sarcoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0042383-&&-sarcolemma-%%-GO:0033162-&&-melanosome membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DTNBP1				DTNBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DTNBP1	0.416083009	0.38067534	0.03776379	76	4	0.00199896	FALSE	4.142857143	DTNBP1	DTNBP1	58.55405405	4.35	0	75	0	0.72884827	FALSE	1	DTNBP1	248062	Infinity	0.02473563
787706	taxon:9606	2.52560265	257.7419072	1.50E-04	162526	1902	histone cluster 1 H2B family member a	gene	biological_process-&-1&-GO:0031639-&&-plasminogen activation-%%-GO:0051099-&&-positive regulation of binding-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0006954-&&-inflammatory response-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071674-&&-mononuclear cell migration-%%-GO:0035093-&&-spermatogenesis, exchange of chromosomal proteins|cellular_component-&-1&-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0000786-&&-nucleosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BA			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BA	0.460126219	0.3959451	0.11368421	76	4	0.008304695	FALSE	7.186046512	HIST1H2BA	HIST1H2BA	111.2894737	7.394736842	0	76	0	0.74573289	FALSE	0	HIST1H2BA	240036	Infinity	0.03732411
787880	taxon:9606	2.47991177	333.064633	9.78E-05	178663	1902	proteasome subunit beta 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB2			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB2	0.47880597	0.40324015	0.3877193	76	4	0.011461508	FALSE	31.38461538	PSMB2	PSMB2	152.2894737	32.98045546	0	76	0	0.75334804	FALSE	0	PSMB2	193658	Infinity	0.04692239
792243	taxon:9606	2.46919805	430.7036035	1.61E-04	182357	1902	ATPase H+ transporting V1 subunit A	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0006810-&&-transport-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification|cellular_component-&-1&-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016469-&&-proton-transporting two-sector ATPase complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6V1A			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1A	0.475682088	0.40498979	0.11699371	76	4	0.008879039	FALSE	10.42857143	ATP6V1A	ATP6V1A	135.527027	10.80479909	0	75	0	0.75513366	FALSE	1	ATP6V1A	269372	Infinity	0.04056886
788202	taxon:9606	2.37781629	347.3825488	2.42E-04	178094	1902	RB transcriptional corepressor like 1	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:RBL1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	RBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBL1	0.489472078	0.42055394	0.12180674	76	4	0.009560221	FALSE	11.47916667	RBL1	RBL1	154.2567568	11.87721335	0	75	0	0.77036395	FALSE	1	RBL1	373758	Infinity	0.03955276
792416	taxon:9606	2.41562943	272.8730564	2.68E-04	182058	1902	CSK, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0042997-&&-negative regulation of Golgi to plasma membrane protein transport-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0034332-&&-adherens junction organization-%%-GO:0030154-&&-cell differentiation-%%-GO:0060368-&&-regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0010989-&&-negative regulation of low-density lipoprotein particle clearance-%%-GO:0007417-&&-central nervous system development-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007420-&&-brain development-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0045121-&&-membrane raft-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:CSK			KEGG-&-1&-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	CSK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSK	0.473295958	0.41397078	0.12884117	76	4	0.007293096	FALSE	12.20454545	CSK	CSK	134.1351351	12.66493356	0	75	0	0.76406176	FALSE	1	CSK	362498	Infinity	0.03673559
788322	taxon:9606	2.37687096	410.9927157	1.27E-04	177887	1902	scaffold attachment factor B	gene	biological_process-&-1&-GO:0050684-&&-regulation of mRNA processing-%%-GO:0006325-&&-chromatin organization-%%-GO:0040007-&&-growth-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SAFB				SAFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAFB	0.492175514	0.4207212	0.15964912	76	4	0.014040551	FALSE	13.24137931	SAFB	SAFB	181.2368421	13.66298908	0	76	0	0.77052151	FALSE	0	SAFB	271772	Infinity	0.04634028
792439	taxon:9606	2.38742713	359.9682462	3.62E-04	182020	1902	C-terminal binding protein 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0048386-&&-positive regulation of retinoic acid receptor signaling pathway-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019079-&&-viral genome replication-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005634-&&-nucleus-%%-GO:0097470-&&-ribbon synapse-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0016616-&&-oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0051287-&&-NAD binding	G:9606:CTBP2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	CTBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTBP2	0.477523072	0.41886095	0.05405405	76	4	0.007243897	FALSE	6.842105263	CTBP2	CTBP2	122.0135135	7.075787769	0	75	0	0.76876214	FALSE	1	CTBP2	454664	Infinity	0.03187676
792798	taxon:9606	2.29021585	366.793211	1.02E-04	181355	1902	eukaryotic translation initiation factor 4A1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006413-&&-translational initiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004386-&&-helicase activity	G:9606:EIF4A1			KEGG-&-1&-hsa03013-&&-RNA transport	EIF4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4A1	0.498756219	0.43664007	0.22596491	76	4	0.023382287	FALSE	18.63636364	EIF4A1	EIF4A1	273.631579	19.51087611	0	76	0	0.78496402	FALSE	0	EIF4A1	284760	Infinity	0.06151789
788792	taxon:9606	2.42713093	522.0108261	1.00E-04	176880	1902	DExD-box helicase 39B	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:2000002-&&-negative regulation of DNA damage checkpoint-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0001889-&&-liver development-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0000346-&&-transcription export complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005688-&&-U6 snRNP|molecular_function-&-1&-GO:0030621-&&-U4 snRNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0008186-&&-RNA-dependent ATPase activity-%%-GO:0017070-&&-U6 snRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0043008-&&-ATP-dependent protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:DDX39B			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa05164-&&-Influenza A-%%-hsa03015-&&-mRNA surveillance pathway	DDX39B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX39B	0.489920586	0.41200909	0.13957793	76	4	0.015271627	FALSE	13.15254237	DDX39B	DDX39B	191.8513514	13.9558505	0	75	0	0.76214485	FALSE	1	DDX39B	228112	Infinity	0.05335113
788832	taxon:9606	2.40664881	428.2444343	3.63E-04	176790	1902	ubiquitin fusion degradation 1 like (yeast)	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036501-&&-UFD1-NPL4 complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:UFD1L			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UFD1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UFD1L	0.485325265	0.41551555	0.08385965	76	4	0.008536566	FALSE	7.918367347	UFD1L	UFD1L	126.5657895	8.262298146	0	76	0	0.76555853	FALSE	0	UFD1L	445652	Infinity	0.03409349
789105	taxon:9606	2.4178352	480.417724	1.19E-04	176185	1902	cyclin A1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007141-&&-male meiosis I-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097123-&&-cyclin A1-CDK2 complex-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCNA1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04110-&&-Cell cycle-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection	CCNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNA1	0.490369917	0.41359312	0.11514254	76	4	0.011292922	FALSE	11.54385965	CCNA1	CCNA1	152.1081081	12.10890183	0	75	0	0.76369413	FALSE	1	CCNA1	221190	Infinity	0.04176938
789380	taxon:9606	2.44840082	362.1880321	3.24E-04	175623	1902	VAMP associated protein B and C	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0090114-&&-COPII-coated vesicle budding-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:0045070-&&-positive regulation of viral genome replication|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0033149-&&-FFAT motif binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:VAPB			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	VAPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAPB	0.473295958	0.40842986	0.06664198	76	4	0.006238373	FALSE	7.5	VAPB	VAPB	112.7567568	7.82390873	0	75	0	0.75859986	FALSE	1	VAPB	389416	Infinity	0.032673
789874	taxon:9606	2.25492359	348.5857841	1.66E-04	174460	1902	DnaJ heat shock protein family (Hsp40) member A2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0009408-&&-response to heat-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0042026-&&-protein refolding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:DNAJA2			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA2	0.501093408	0.44347401	0.17333333	76	4	0.016514724	FALSE	15.08196721	DNAJA2	DNAJA2	245.9473684	15.49287136	0	76	0	0.79084607	FALSE	0	DNAJA2	425278	Infinity	0.05261469
789893	taxon:9606	2.38333071	934.5240391	1.76E-04	174414	1902	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	gene	biological_process-&-1&-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0009113-&&-purine nucleobase biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004638-&&-phosphoribosylaminoimidazole carboxylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004639-&&-phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	G:9606:PAICS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	PAICS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAICS	0.492175514	0.41958088	0.09218808	76	4	0.011641029	FALSE	9.573770492	PAICS	PAICS	177.9864865	10.63418463	0	75	0	0.76944488	FALSE	1	PAICS	352312	Infinity	0.04604877
790032	taxon:9606	2.36221837	765.0284829	1.16E-04	174055	1902	cleavage and polyadenylation specific factor 6	gene	biological_process-&-1&-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006397-&&-mRNA processing-%%-GO:0051262-&&-protein tetramerization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005849-&&-mRNA cleavage factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0042382-&&-paraspeckles-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:CPSF6			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CPSF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPSF6	0.498756219	0.42333089	0.15719298	76	4	0.015555073	FALSE	12.765625	CPSF6	CPSF6	206.1842105	13.62742349	0	76	0	0.7729636	FALSE	0	CPSF6	268972	Infinity	0.05156855
790130	taxon:9606	2.43532378	281.3746224	1.70E-04	173800	1902	RALY heterogeneous nuclear ribonucleoprotein	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:RALY				RALY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RALY	0.489173529	0.41062302	0.24947368	76	4	0.022453722	FALSE	22.07936508	RALY	RALY	254	22.66248586	0	76	0	0.76077937	FALSE	0	RALY	352588	Infinity	0.07169604
790516	taxon:9606	2.5341106	263.0904283	1.86E-04	172647	1902	TERF1 interacting nuclear factor 2	gene	biological_process-&-1&-GO:0034502-&&-protein localization to chromosome-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0010836-&&-negative regulation of protein ADP-ribosylation-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0016233-&&-telomere capping-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0032202-&&-telomere assembly|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0016604-&&-nuclear body-%%-GO:0010370-&&-perinucleolar chromocenter-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0070187-&&-shelterin complex-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0010521-&&-telomerase inhibitor activity	G:9606:TINF2				TINF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TINF2	0.455423055	0.39461577	0.06773212	75	4	0.006306449	FALSE	7.435897436	TINF2	TINF2	94.69863014	7.635964912	0	74	0	0.7443149	FALSE	1	TINF2	239012	Infinity	0.03240118
791156	taxon:9606	2.42807626	374.2056736	1.22E-04	169865	1902	ring finger protein 126	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0071629-&&-ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF126				RNF126	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF126	0.483569491	0.41184868	0.0890411	75	4	0.009090493	FALSE	9.557692308	RNF126	RNF126	139.1506849	9.827627754	0	74	0	0.76198729	FALSE	1	RNF126	220328	Infinity	0.03883893
787126	taxon:9606	2.34394202	705.8409678	2.18E-04	163633	1902	angiomotin	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0034613-&&-cellular protein localization-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0040019-&&-positive regulation of embryonic development-%%-GO:0035329-&&-hippo signaling-%%-GO:0042074-&&-cell migration involved in gastrulation-%%-GO:0003365-&&-establishment of cell polarity involved in ameboidal cell migration-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0006935-&&-chemotaxis-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043534-&&-blood vessel endothelial cell migration-%%-GO:0034260-&&-negative regulation of GTPase activity|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0001726-&&-ruffle-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043532-&&-angiostatin binding	G:9606:AMOT			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction	AMOT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMOT	0.493234932	0.42663171	0.08751903	75	4	0.009135416	FALSE	8.388888889	AMOT	AMOT	158.4109589	8.966965473	0	74	0	0.77600966	FALSE	1	AMOT	373878	Infinity	0.03858308
788125	taxon:9606	2.44729794	360.7478172	3.57E-04	178200	1902	protein tyrosine phosphatase, receptor type J	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0060242-&&-contact inhibition-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0043116-&&-negative regulation of vascular permeability-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030308-&&-negative regulation of cell growth|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001772-&&-immunological synapse-%%-GO:0009986-&&-cell surface-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0070097-&&-delta-catenin binding-%%-GO:0045295-&&-gamma-catenin binding	G:9606:PTPRJ			KEGG-&-1&-hsa04520-&&-Adherens junction	PTPRJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRJ	0.462914863	0.40861392	0.0825723	75	4	0.005322009	FALSE	10.375	PTPRJ	PTPRJ	116.3287671	10.81383873	0	74	0	0.75878368	FALSE	1	PTPRJ	413646	Infinity	0.033566
788223	taxon:9606	2.40003151	261.5782468	9.72E-05	178055	1902	replication factor C subunit 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0003689-&&-DNA clamp loader activity	G:9606:RFC1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC1	0.487241798	0.4166612	0.20243531	75	4	0.015291693	FALSE	16.82758621	RFC1	RFC1	217.1232877	17.25597274	0	74	0	0.76666141	FALSE	1	RFC1	254342	Infinity	0.0576886
792555	taxon:9606	2.49724279	297.3455869	1.61E-04	181817	1902	runt related transcription factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001503-&&-ossification-%%-GO:0071425-&&-hematopoietic stem cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0048935-&&-peripheral nervous system neuron development-%%-GO:0030854-&&-positive regulation of granulocyte differentiation-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0002062-&&-chondrocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0005515-&&-protein binding-%%-GO:0000975-&&-regulatory region DNA binding	G:9606:RUNX1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04530-&&-Tight junction-%%-hsa05220-&&-Chronic myeloid leukemia	RUNX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUNX1	0.460522538	0.40044164	0.15715373	75	4	0.007838238	FALSE	14.86538462	RUNX1	RUNX1	132.9315069	15.44614106	0	74	0	0.75045953	FALSE	1	RUNX1	253282	Infinity	0.04194773
788598	taxon:9606	2.52796597	241.7405772	5.94E-04	177371	1902	elongin B	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0030891-&&-VCB complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070449-&&-elongin complex|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:ELOB			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	ELOB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELOB	0.46091954	0.39557495	0.08900901	75	4	0.007790504	FALSE	7.675675676	ELOB	ELOB	109.3866667	7.888888889	0	75	0	0.74533901	FALSE	0	ELOB	1186544	Infinity	0.03678439
789156	taxon:9606	2.45391524	404.4872154	1.42E-04	176087	1902	ASH2 like histone lysine methyltransferase complex subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030097-&&-hemopoiesis-%%-GO:0043627-&&-response to estrogen-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0048188-&&-Set1C/COMPASS complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990188-&&-euchromatin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:ASH2L			KEGG-&-1&-hsa04934-&&-Cushing syndrome	ASH2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASH2L	0.477096966	0.40751204	0.17922374	75	4	0.011692012	FALSE	13.7	ASH2L	ASH2L	172.109589	14.22495062	0	74	0	0.75768079	FALSE	1	ASH2L	299126	Infinity	0.04992231
789397	taxon:9606	2.40775169	451.1281623	2.14E-04	175569	1902	serine and arginine rich splicing factor 11	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRSF11				SRSF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF11	0.494298921	0.41532522	0.21693694	75	4	0.015201189	FALSE	18.13636364	SRSF11	SRSF11	176.5066667	19.14899275	0	75	0	0.76537472	FALSE	0	SRSF11	350302	Infinity	0.04757233
790025	taxon:9606	2.50764141	354.2572856	2.71E-04	174070	1902	destrin, actin depolymerizing factor	gene	biological_process-&-1&-GO:0030836-&&-positive regulation of actin filament depolymerization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0030043-&&-actin filament fragmentation-%%-GO:0030042-&&-actin filament depolymerization-%%-GO:0051014-&&-actin filament severing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding	G:9606:DSTN				DSTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSTN	0.467911319	0.3987811	0.0781982	75	4	0.007650547	FALSE	7.146341463	DSTN	DSTN	112.16	7.335934561	0	75	0	0.74872643	FALSE	0	DSTN	368040	Infinity	0.03648003
790385	taxon:9606	2.41925319	334.8696285	2.56E-04	173152	1902	CD2 associated protein	gene	biological_process-&-1&-GO:0016050-&&-vesicle organization-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0051301-&&-cell division-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0032911-&&-negative regulation of transforming growth factor beta1 production-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0048259-&&-regulation of receptor-mediated endocytosis-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0001726-&&-ruffle-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0031941-&&-filamentous actin|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005172-&&-vascular endothelial growth factor receptor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0045296-&&-cadherin binding	G:9606:CD2AP			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	CD2AP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD2AP	0.479091995	0.4133507	0.10312024	75	4	0.007659924	FALSE	11.26666667	CD2AP	CD2AP	133.4383562	11.59254215	0	74	0	0.7634578	FALSE	1	CD2AP	348036	Infinity	0.03674358
790551	taxon:9606	2.37765874	312.9172267	6.78E-05	172256	1902	G protein nucleolar 3	gene	biological_process-&-1&-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:1904816-&&-positive regulation of protein localization to chromosome, telomeric region-%%-GO:0008283-&&-cell proliferation-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005615-&&-extracellular space-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:GNL3			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	GNL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNL3	0.492780338	0.4205818	0.37245465	74	4	0.023416253	FALSE	29.42424242	GNL3	GNL3	249.3918919	30.19289019	0	74	0	0.77039021	FALSE	0	GNL3	188394	Infinity	0.06381228
790623	taxon:9606	2.48526863	281.8338904	1.69E-04	171725	1902	protein phosphatase methylesterase 1	gene	biological_process-&-1&-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006482-&&-protein demethylation|molecular_function-&-1&-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0051722-&&-protein C-terminal methylesterase activity	G:9606:PPME1				PPME1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPME1	0.470933647	0.40237099	0.10093897	74	4	0.008260714	FALSE	9.155555556	PPME1	PPME1	121.2083333	9.570032745	0	73	0	0.75245523	FALSE	1	PPME1	247690	Infinity	0.03745921
790817	taxon:9606	2.50968962	549.7656964	1.27E-04	171123	1902	WD repeat containing, antisense to TP73	gene	biological_process-&-1&-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0030030-&&-cell projection organization-%%-GO:0090307-&&-mitotic spindle assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005814-&&-centriole-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WRAP73				WRAP73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WRAP73	0.472181336	0.39845565	0.06885759	74	4	0.006674838	FALSE	7.541666667	WRAP73	WRAP73	108.0833333	7.815158023	0	73	0	0.74838506	FALSE	1	WRAP73	206308	Infinity	0.03501495
791007	taxon:9606	2.51347093	313.5177665	9.84E-05	170426	1902	methyl-CpG binding domain protein 3	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0007420-&&-brain development-%%-GO:0048568-&&-embryonic organ development-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0009888-&&-tissue development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0007568-&&-aging-%%-GO:0016573-&&-histone acetylation-%%-GO:0032355-&&-response to estradiol-%%-GO:0016575-&&-histone deacetylation-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0006346-&&-methylation-dependent chromatin silencing|cellular_component-&-1&-GO:0016581-&&-NuRD complex-%%-GO:0000792-&&-heterochromatin-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:MBD3				MBD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBD3	0.470795421	0.3978562	0.22456964	74	4	0.013110884	FALSE	17.54385965	MBD3	MBD3	175.6666667	17.99895435	0	73	0	0.74775484	FALSE	1	MBD3	229540	Infinity	0.05686846
791146	taxon:9606	2.44572239	501.8517931	1.08E-04	169890	1902	autophagy and beclin 1 regulator 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:0016236-&&-macroautophagy-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0021915-&&-neural tube development-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005930-&&-axoneme-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:AMBRA1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04137-&&-Mitophagy - animal	AMBRA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMBRA1	0.485766202	0.40887715	0.20325805	74	4	0.011913339	FALSE	16.92063492	AMBRA1	AMBRA1	160.9054054	17.53086737	0	74	0	0.75904627	FALSE	0	AMBRA1	210916	Infinity	0.04626931
787133	taxon:9606	2.33874271	624.1729636	1.75E-04	180010	1902	inosine monophosphate dehydrogenase 2	gene	biological_process-&-1&-GO:0006177-&&-GMP biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0046651-&&-lymphocyte proliferation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006183-&&-GTP biosynthetic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003938-&&-IMP dehydrogenase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0046872-&&-metal ion binding	G:9606:IMPDH2			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	IMPDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IMPDH2	0.496133622	0.42758017	0.10289515	74	4	0.015974456	FALSE	10.45762712	IMPDH2	IMPDH2	224.9166667	11.02733597	0	73	0	0.77687621	FALSE	1	IMPDH2	349182	Infinity	0.05433046
791237	taxon:9606	2.41925319	621.8542434	1.53E-04	169566	1902	ring finger protein 20	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:0031062-&&-positive regulation of histone methylation-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0033503-&&-HULC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0042393-&&-histone binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:RNF20				RNF20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF20	0.484885127	0.4133507	0.10289515	74	4	0.012426632	FALSE	9.428571429	RNF20	RNF20	168.7361111	9.979152571	0	73	0	0.7634578	FALSE	1	RNF20	295378	Infinity	0.04625187
791368	taxon:9606	2.46147786	321.6383284	1.49E-04	168946	1902	ubiquitin specific peptidase 37	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0035871-&&-protein K11-linked deubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP37				USP37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP37	0.482406015	0.40626	0.1185446	74	4	0.010699426	FALSE	11.68	USP37	USP37	148.1527778	12.02134175	0	73	0	0.75642036	FALSE	1	USP37	235606	Infinity	0.04362216
787607	taxon:9606	2.35402552	275.9505544	2.91E-04	179111	1902	NFKB inhibitor beta	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:NFKBIB			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NFKBIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKBIB	0.488726386	0.42480423	0.12558685	74	4	0.012040626	FALSE	13.36538462	NFKBIB	NFKBIB	168.2916667	13.65639939	0	73	0	0.77432908	FALSE	1	NFKBIB	386896	Infinity	0.04163916
787648	taxon:9606	2.37781629	441.5220555	3.71E-04	179019	1902	N-ethylmaleimide sensitive factor, vesicle fusing ATPase	gene	biological_process-&-1&-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006813-&&-potassium ion transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0045026-&&-plasma membrane fusion-%%-GO:0006887-&&-exocytosis-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0035494-&&-SNARE complex disassembly|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043198-&&-dendritic shaft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005829-&&-cytosol-%%-GO:0005795-&&-Golgi stack-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0046872-&&-metal ion binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005524-&&-ATP binding	G:9606:NSF			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04727-&&-GABAergic synapse-%%-hsa04721-&&-Synaptic vesicle cycle	NSF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSF	0.483278096	0.42055394	0.07550861	74	4	0.00874388	FALSE	8.125	NSF	NSF	161.1666667	8.403664756	0	73	0	0.77036395	FALSE	1	NSF	544778	Infinity	0.04133174
792132	taxon:9606	2.35985505	148.733171	4.24E-04	182543	1902	actin, alpha 2, smooth muscle, aorta	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006936-&&-muscle contraction-%%-GO:0072144-&&-glomerular mesangial cell development-%%-GO:0009615-&&-response to virus-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0090131-&&-mesenchyme migration-%%-GO:0014829-&&-vascular smooth muscle contraction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0044297-&&-cell body-%%-GO:0030027-&&-lamellipodium-%%-GO:0030485-&&-smooth muscle contractile fiber-%%-GO:0043234-&&-protein complex-%%-GO:0030175-&&-filopodium-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding	G:9606:ACTA2			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway	ACTA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTA2	0.488577521	0.42375484	0.12217697	74	4	0.015717212	FALSE	12.46808511	ACTA2	ACTA2	192.1351351	12.73913043	0	74	0	0.77335749	FALSE	0	ACTA2	627226	Infinity	0.04796403
792672	taxon:9606	2.31904837	487.1338254	1.12E-04	181583	1902	aspartyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006412-&&-translation-%%-GO:0006422-&&-aspartyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004046-&&-aminoacylase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004815-&&-aspartate-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:DARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	DARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DARS	0.496902107	0.43121136	0.23102555	74	4	0.018755741	FALSE	16.42857143	DARS	DARS	234.1081081	17.3559753	0	74	0	0.78015861	FALSE	0	DARS	289434	Infinity	0.0549034
793068	taxon:9606	2.40176461	334.4713768	2.21E-04	180808	1902	general transcription factor IIF subunit 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009615-&&-response to virus-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005674-&&-transcription factor TFIIF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019211-&&-phosphatase activator activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0003723-&&-RNA binding	G:9606:GTF2F1			KEGG-&-1&-hsa03022-&&-Basal transcription factors	GTF2F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2F1	0.486945962	0.41636054	0.11810441	74	4	0.008656287	FALSE	8.068181818	GTF2F1	GTF2F1	144.2162162	8.45014207	0	74	0	0.76637256	FALSE	0	GTF2F1	342404	Infinity	0.03829008
789124	taxon:9606	2.44651016	312.3187388	9.84E-05	159768	1902	small ubiquitin-like modifier 4	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031386-&&-protein tag	G:9606:SUMO4			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO4	0.480671262	0.40874549	0.08626435	74	4	0.010213934	FALSE	7.169811321	SUMO4	SUMO4	134.7837838	7.369790627	0	74	0	0.75891497	FALSE	0	SUMO4	184796	Infinity	0.03893579
789281	taxon:9606	2.50953206	108.8764877	2.57E-04	175834	1902	cytosolic iron-sulfur assembly component 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0016226-&&-iron-sulfur cluster assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007059-&&-chromosome segregation|cellular_component-&-1&-GO:0071817-&&-MMXD complex-%%-GO:0097361-&&-CIA complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CIAO1				CIAO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CIAO1	0.446423601	0.39848066	0.03146983	74	4	0.004625645	FALSE	1.925925926	CIAO1	CIAO1	85.95945946	2	0	74	0	0.74841132	FALSE	0	CIAO1	291724	Infinity	0.02798913
789315	taxon:9606	2.49960611	532.2778977	1.62E-04	175767	1902	autophagy related 5	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0009620-&&-response to fungus-%%-GO:0016236-&&-macroautophagy-%%-GO:0043687-&&-post-translational protein modification-%%-GO:0060047-&&-heart contraction-%%-GO:0042311-&&-vasodilation-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0070257-&&-positive regulation of mucus secretion-%%-GO:0044804-&&-nucleophagy-%%-GO:0071500-&&-cellular response to nitrosative stress-%%-GO:0006914-&&-autophagy-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0019883-&&-antigen processing and presentation of endogenous antigen-%%-GO:0035973-&&-aggrephagy-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0039689-&&-negative stranded viral RNA replication-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0000422-&&-mitophagy-%%-GO:0002739-&&-regulation of cytokine secretion involved in immune response-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0048840-&&-otolith development-%%-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0042493-&&-response to drug-%%-GO:0061739-&&-protein lipidation involved in autophagosome assembly-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:2000619-&&-negative regulation of histone H4-K16 acetylation-%%-GO:0001974-&&-blood vessel remodeling|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0005776-&&-autophagosome-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0005829-&&-cytosol-%%-GO:0034274-&&-Atg12-Atg5-Atg16 complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0044233-&&-ER-mitochondrion membrane contact site-%%-GO:0030670-&&-phagocytic vesicle membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019776-&&-Atg8 ligase activity	G:9606:ATG5			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05131-&&-Shigellosis-%%-hsa04136-&&-Autophagy - other-%%-hsa04216-&&-Ferroptosis-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	ATG5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG5	0.469830111	0.40006303	0.05203443	74	4	0.006693716	FALSE	6.333333333	ATG5	ATG5	102.5	6.692283386	0	73	0	0.75006565	FALSE	1	ATG5	237194	Infinity	0.03283071
789537	taxon:9606	2.50968962	324.0362756	7.53E-05	175233	1902	histone deacetylase 9	gene	biological_process-&-1&-GO:0070933-&&-histone H4 deacetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051153-&&-regulation of striated muscle cell differentiation-%%-GO:0007507-&&-heart development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030183-&&-B cell differentiation-%%-GO:0048742-&&-regulation of skeletal muscle fiber development-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0090050-&&-positive regulation of cell migration involved in sprouting angiogenesis-%%-GO:0001975-&&-response to amphetamine-%%-GO:0016575-&&-histone deacetylation-%%-GO:0042113-&&-B cell activation-%%-GO:0006954-&&-inflammatory response-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0003714-&&-transcription corepressor activity	G:9606:HDAC9			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC9	0.466686063	0.39845565	0.15453834	74	4	0.013046201	FALSE	14.68965517	HDAC9	HDAC9	162.8611111	15.1187583	0	73	0	0.74838506	FALSE	1	HDAC9	179944	Infinity	0.05249302
789780	taxon:9606	2.32125414	832.4444906	3.84E-04	174693	1902	tyrosine kinase non receptor 2	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:2000369-&&-regulation of clathrin-dependent endocytosis-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0030154-&&-cell differentiation-%%-GO:0006897-&&-endocytosis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070436-&&-Grb2-EGFR complex-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005524-&&-ATP binding	G:9606:TNK2				TNK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNK2	0.49202454	0.4308016	0.09741784	74	4	0.007888909	FALSE	10.32653061	TNK2	TNK2	161.2361111	11.16387326	0	73	0	0.77979098	FALSE	1	TNK2	526626	Infinity	0.0379281
789928	taxon:9606	2.35812195	314.4269853	1.54E-04	174333	1902	ubiquitin specific peptidase 39	gene	biological_process-&-1&-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:USP39			KEGG-&-1&-hsa03040-&&-Spliceosome	USP39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP39	0.49247774	0.42406628	0.17882266	74	4	0.013830429	FALSE	15.85454545	USP39	USP39	184.3513514	16.3894779	0	74	0	0.77364634	FALSE	0	USP39	277636	Infinity	0.04595943
790748	taxon:9606	2.35591618	263.6139627	1.81E-04	171338	1902	COP9 signalosome subunit 4	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0019784-&&-NEDD8-specific protease activity-%%-GO:0005515-&&-protein binding	G:9606:COPS4				COPS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS4	0.488280061	0.42446332	0.21609658	73	4	0.011953868	FALSE	17.77777778	COPS4	COPS4	184.2394366	18.46619133	0	72	0	0.77401397	FALSE	1	COPS4	325078	Infinity	0.04560465
790821	taxon:9606	2.40932724	512.3803146	2.54E-04	171093	1902	gem nuclear organelle associated protein 4	gene	biological_process-&-1&-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006364-&&-rRNA processing-%%-GO:0051170-&&-nuclear import|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0016604-&&-nuclear body-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GEMIN4			KEGG-&-1&-hsa03013-&&-RNA transport	GEMIN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GEMIN4	0.484007242	0.41505362	0.11750503	73	4	0.010354644	FALSE	10.74	GEMIN4	GEMIN4	165.056338	11.25029534	0	72	0	0.76511213	FALSE	1	GEMIN4	390692	Infinity	0.04448259
790989	taxon:9606	2.51441626	319.2920835	1.22E-04	170483	1902	HAUS augmin like complex subunit 2	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005876-&&-spindle microtubule-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:HAUS2				HAUS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS2	0.47273799	0.39770662	0.09208524	73	4	0.008944896	FALSE	7.130434783	HAUS2	HAUS2	119.6164384	7.329382056	0	73	0	0.74759729	FALSE	0	HAUS2	206164	Infinity	0.03905519
787153	taxon:9606	2.50338743	625.6319836	2.79E-04	179975	1902	LIM domain only 2	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070888-&&-E-box binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0048037-&&-cofactor binding	G:9606:LMO2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	LMO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMO2	0.458810069	0.39945875	0.05593561	73	4	0.004772136	FALSE	6.261904762	LMO2	LMO2	98.70422535	6.875738367	0	72	0	0.74943543	FALSE	1	LMO2	343336	Infinity	0.03176274
791265	taxon:9606	2.52954152	413.2511636	2.50E-04	169443	1902	zinc finger protein 512B	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF512B				ZNF512B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF512B	0.465062337	0.39532856	0.08980213	73	4	0.009870273	FALSE	9.333333333	ZNF512B	ZNF512B	142.9726027	9.594918609	0	73	0	0.74507641	FALSE	0	ZNF512B	396892	Infinity	0.048471
787210	taxon:9606	2.31936348	238.0358659	1.69E-04	179863	1902	methionyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006431-&&-methionyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004825-&&-methionine-tRNA ligase activity-%%-GO:0000049-&&-tRNA binding	G:9606:MARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa00450-&&-Selenocompound metabolism	MARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARS	0.495520544	0.43115277	0.17770167	73	4	0.016200801	FALSE	13.60377358	MARS	MARS	230.1369863	14.13064288	0	73	0	0.78010609	FALSE	0	MARS	323776	Infinity	0.05395924
787293	taxon:9606	2.52150622	137.9386017	8.19E-04	179720	1902	kinase insert domain receptor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:0016032-&&-viral process-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0001570-&&-vasculogenesis-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0003158-&&-endothelium development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030054-&&-cell junction-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0097443-&&-sorting endosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity	G:9606:KDR	KDR	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	KDR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDR	0.457110288	0.39658835	0.0889336	73	4	0.005353744	FALSE	10.51515152	KDR	KDR	105.6197183	10.84375	0	72	0	0.74641563	FALSE	1	KDR	1014144	Infinity	0.03521362
787480	taxon:9606	2.57239641	233.341443	2.20E-04	179353	1902	myeloid leukemia factor 1	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated-%%-GO:0002318-&&-myeloid progenitor cell differentiation-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:MLF1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	MLF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLF1	0.439211391	0.38874257	0.06197183	73	4	0.004407423	FALSE	6.71875	MLF1	MLF1	82.11267606	7.01827957	0	72	0	0.73793393	FALSE	1	MLF1	244186	Infinity	0.03052867
791979	taxon:9606	2.44981881	323.7536805	1.57E-04	182776	1902	baculoviral IAP repeat containing 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0039535-&&-regulation of RIG-I signaling pathway-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:2000116-&&-regulation of cysteine-type endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070424-&&-regulation of nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045088-&&-regulation of innate immune response|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0016740-&&-transferase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:BIRC3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	BIRC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC3	0.469417618	0.40819345	0.1778672	73	4	0.007105513	FALSE	15.83018868	BIRC3	BIRC3	135.4788732	16.74542147	0	72	0	0.75836353	FALSE	1	BIRC3	256626	Infinity	0.03931482
787887	taxon:9606	2.56861509	231.428038	4.92E-05	178658	1902	proteasome subunit beta 7	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB7			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB7	0.459204123	0.38931485	0.42414487	73	4	0.008388675	FALSE	32.8	PSMB7	PSMB7	120.8309859	34.03890508	0	72	0	0.73856415	FALSE	1	PSMB7	108262	Infinity	0.04450497
792077	taxon:9606	2.45895699	428.7412958	3.72E-04	182652	1902	chloride nucleotide-sensitive channel 1A	gene	biological_process-&-1&-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006884-&&-cell volume homeostasis-%%-GO:0006821-&&-chloride transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:CLNS1A			KEGG-&-1&-hsa03013-&&-RNA transport	CLNS1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLNS1A	0.472877358	0.40667649	0.09056317	73	4	0.010284421	FALSE	8.04	CLNS1A	CLNS1A	136.8630137	8.358412749	0	73	0	0.7568405	FALSE	0	CLNS1A	508742	Infinity	0.04044763
792120	taxon:9606	2.37718607	477.1714002	1.62E-04	182574	1902	coatomer protein complex subunit alpha	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0030157-&&-pancreatic juice secretion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005198-&&-structural molecule activity	G:9606:COPA	COPA	TRUE		COPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPA	0.48783455	0.42066543	0.14366197	73	4	0.014112542	FALSE	12.52830189	COPA	COPA	220.028169	12.98515152	0	72	0	0.77046899	FALSE	1	COPA	347286	Infinity	0.05631639
788019	taxon:9606	2.3415787	389.7745724	1.71E-04	178388	1902	phosphofructokinase, platelet	gene	biological_process-&-1&-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0061621-&&-canonical glycolysis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003872-&&-6-phosphofructokinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0045296-&&-cadherin binding	G:9606:PFKP			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa00052-&&-Galactose metabolism-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03018-&&-RNA degradation-%%-hsa00030-&&-Pentose phosphate pathway	PFKP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKP	0.494603762	0.42706231	0.11111111	73	4	0.014117322	FALSE	9.25	PFKP	PFKP	215.739726	9.528011585	0	73	0	0.77640355	FALSE	0	PFKP	358008	Infinity	0.05235071
788098	taxon:9606	2.45013392	336.8247951	1.90E-04	178246	1902	progesterone receptor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0051117-&&-ATPase binding	G:9606:PGR	PGR	TRUE	KEGG-&-1&-hsa04114-&&-Oocyte meiosis-%%-hsa05224-&&-Breast cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04915-&&-Estrogen signaling pathway	PGR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGR	0.477807566	0.40814096	0.1110664	73	4	0.00856508	FALSE	11.19565217	PGR	PGR	136.9295775	11.58978857	0	72	0	0.75831101	FALSE	1	PGR	298580	Infinity	0.03969716
788208	taxon:9606	2.46730739	752.4802822	1.72E-04	178078	1902	reticulocalbin 1	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0043010-&&-camera-type eye development|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:RCN1				RCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCN1	0.476105669	0.40530013	0.08143075	73	4	0.009571976	FALSE	7.641509434	RCN1	RCN1	138.2465753	8.25019225	0	73	0	0.75544877	FALSE	0	RCN1	304412	Infinity	0.04139137
792401	taxon:9606	2.41373877	265.8274599	6.74E-04	182090	1902	crystallin alpha B	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:1905907-&&-negative regulation of amyloid fibril formation-%%-GO:0010941-&&-regulation of cell death-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006936-&&-muscle contraction-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032387-&&-negative regulation of intracellular transport-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0031109-&&-microtubule polymerization or depolymerization-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006457-&&-protein folding-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0071480-&&-cellular response to gamma radiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0031674-&&-I band-%%-GO:0032432-&&-actin filament bundle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097512-&&-cardiac myofibril-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0097060-&&-synaptic membrane-%%-GO:0031430-&&-M band-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0005212-&&-structural constituent of eye lens-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:CRYAB			KEGG-&-1&-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CRYAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRYAB	0.461449942	0.41429504	0.06036217	73	4	0.004872174	FALSE	7.794117647	CRYAB	CRYAB	108.3098592	8.033333333	0	72	0	0.76437687	FALSE	1	CRYAB	586480	Infinity	0.02955053
788442	taxon:9606	2.49472192	320.4291721	2.94E-04	177670	1902	SKI like proto-oncogene	gene	biological_process-&-1&-GO:0034097-&&-response to cytokine-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0007283-&&-spermatogenesis-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0048666-&&-neuron development-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0001825-&&-blastocyst formation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0002260-&&-lymphocyte homeostasis|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046332-&&-SMAD binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:SKIL			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	SKIL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKIL	0.470657277	0.40084628	0.08088531	73	4	0.006556368	FALSE	9.43902439	SKIL	SKIL	112.5492958	9.7375	0	72	0	0.75087968	FALSE	1	SKIL	335114	Infinity	0.03559036
788612	taxon:9606	2.46525918	279.7018956	2.18E-04	177308	1902	dynein light chain Tctex-type 1	gene	biological_process-&-1&-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0019060-&&-intracellular transport of viral protein in host cell-%%-GO:0075521-&&-microtubule-dependent intracellular transport of viral material towards nucleus-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051493-&&-regulation of cytoskeleton organization|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005819-&&-spindle-%%-GO:0043657-&&-host cell-%%-GO:0099503-&&-secretory vesicle|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:DYNLT1				DYNLT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNLT1	0.463851938	0.40563686	0.03501006	73	4	0.004488325	FALSE	5.064516129	DYNLT1	DYNLT1	96.16901408	5.233333333	0	72	0	0.75579014	FALSE	1	DYNLT1	279628	Infinity	0.0286955
792820	taxon:9606	2.44272885	343.5020887	1.97E-04	181309	1902	enolase 2	gene	biological_process-&-1&-GO:0006094-&&-gluconeogenesis-%%-GO:0061621-&&-canonical glycolysis|cellular_component-&-1&-GO:0043204-&&-perikaryon-%%-GO:0000015-&&-phosphopyruvate hydratase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0004634-&&-phosphopyruvate hydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:ENO2	ENO2	TRUE	KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03018-&&-RNA degradation-%%-hsa04066-&&-HIF-1 signaling pathway	ENO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENO2	0.477523072	0.40937822	0.16901408	73	4	0.009358569	FALSE	13.375	ENO2	ENO2	146.0422535	13.97528617	0	72	0	0.75954519	FALSE	1	ENO2	316012	Infinity	0.04184972
792838	taxon:9606	2.48968016	519.4733629	2.94E-04	164903	1902	charged multivesicular body protein 4B	gene	biological_process-&-1&-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0016236-&&-macroautophagy-%%-GO:0090611-&&-ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0050792-&&-regulation of viral process-%%-GO:0019058-&&-viral life cycle-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0006997-&&-nucleus organization-%%-GO:0007034-&&-vacuolar transport-%%-GO:0006914-&&-autophagy-%%-GO:0006620-&&-posttranslational protein targeting to membrane-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0016197-&&-endosomal transport-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0010458-&&-exit from mitosis-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0031468-&&-nuclear envelope reassembly-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0036438-&&-maintenance of lens transparency-%%-GO:0046755-&&-viral budding-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0090148-&&-membrane fission|cellular_component-&-1&-GO:0030117-&&-membrane coat-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0000815-&&-ESCRT III complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0030496-&&-midbody-%%-GO:0031902-&&-late endosome membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:CHMP4B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	CHMP4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHMP4B	0.471903501	0.40165802	0.07645875	73	4	0.007603056	FALSE	7.511111111	CHMP4B	CHMP4B	120.028169	7.720238095	0	72	0	0.75171997	FALSE	1	CHMP4B	366196	Infinity	0.03745019
788824	taxon:9606	2.49346148	281.4779697	1.19E-04	176805	1902	ubiquitin conjugating enzyme E2 V1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006301-&&-postreplication repair-%%-GO:0030154-&&-cell differentiation-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0007254-&&-JNK cascade-%%-GO:0000187-&&-activation of MAPK activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031371-&&-ubiquitin conjugating enzyme complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0035370-&&-UBC13-UEV1A complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:UBE2V1				UBE2V1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2V1	0.472181336	0.40104891	0.15694165	73	4	0.007922642	FALSE	13.89795918	UBE2V1	UBE2V1	135.0704225	14.37144511	0	72	0	0.75108975	FALSE	1	UBE2V1	250836	Infinity	0.04242162
788840	taxon:9606	2.41547188	572.266855	1.93E-04	176772	1902	ubiquitin specific peptidase 4	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005764-&&-lysosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031685-&&-adenosine receptor binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:USP4				USP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP4	0.486207942	0.41399778	0.07806841	73	4	0.008463488	FALSE	8.408163265	USP4	USP4	140.7183099	8.739874692	0	72	0	0.76408802	FALSE	1	USP4	304286	Infinity	0.03842454
789058	taxon:9606	2.41137545	404.2932434	9.82E-05	176268	1902	tripartite motif containing 24	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0070562-&&-regulation of vitamin D receptor signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030163-&&-protein catabolic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005726-&&-perichromatin fibrils-%%-GO:0005634-&&-nucleus-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0035064-&&-methylated histone binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0034056-&&-estrogen response element binding	G:9606:TRIM24				TRIM24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM24	0.486207942	0.41470108	0.24869215	73	4	0.017423924	FALSE	20.59375	TRIM24	TRIM24	230.4225352	21.47902475	0	72	0	0.76477076	FALSE	1	TRIM24	263934	Infinity	0.06207124
789259	taxon:9606	2.3018749	402.4489815	2.10E-04	175887	1902	eukaryotic translation initiation factor 3 subunit F	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006413-&&-translational initiation-%%-GO:0075522-&&-IRES-dependent viral translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:EIF3F			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3F	0.492628993	0.43442847	0.16438356	73	4	0.013852036	FALSE	12.68518519	EIF3F	EIF3F	205.890411	13.26386347	0	73	0	0.78302085	FALSE	0	EIF3F	372450	Infinity	0.04713119
789274	taxon:9606	2.42161651	444.898494	1.16E-04	175846	1902	TNFRSF1A associated via death domain	gene	biological_process-&-1&-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0051798-&&-positive regulation of hair follicle development-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0070513-&&-death domain binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0060090-&&-binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding	G:9606:TRADD			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	TRADD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRADD	0.483861237	0.4129473	0.15050302	73	4	0.010381835	FALSE	13.59322034	TRADD	TRADD	146.7042254	14.38063042	0	72	0	0.76306391	FALSE	1	TRADD	232898	Infinity	0.04055185
789762	taxon:9606	2.48054199	362.6330382	3.58E-04	174741	1902	optineurin	gene	biological_process-&-1&-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization-%%-GO:0016236-&&-macroautophagy-%%-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0000042-&&-protein targeting to Golgi-%%-GO:0008219-&&-cell death-%%-GO:0001920-&&-negative regulation of receptor recycling-%%-GO:0007030-&&-Golgi organization-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0043001-&&-Golgi to plasma membrane protein transport-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0090161-&&-Golgi ribbon formation-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:1904417-&&-positive regulation of xenophagy|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0042802-&&-identical protein binding	G:9606:OPTN			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	OPTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPTN	0.46655032	0.4031377	0.07887324	73	4	0.00696583	FALSE	9.428571429	OPTN	OPTN	116.6478873	9.722410271	0	72	0	0.753243	FALSE	1	OPTN	376174	Infinity	0.03580263
790033	taxon:9606	2.42807626	371.1060467	2.63E-04	174049	1902	WW domain containing E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032410-&&-negative regulation of transporter activity-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0051224-&&-negative regulation of protein transport-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0008134-&&-transcription factor binding	G:9606:WWP2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	WWP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWP2	0.48313253	0.41184868	0.06358149	73	4	0.00740096	FALSE	8.113636364	WWP2	WWP2	133.4788732	8.394045581	0	72	0	0.76198729	FALSE	1	WWP2	364650	Infinity	0.03733656
790427	taxon:9606	2.46636206	210.4617862	2.32E-04	173016	1902	DAZ associated protein 1	gene	biological_process-&-1&-GO:0001893-&&-maternal placenta development-%%-GO:0008283-&&-cell proliferation-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding	G:9606:DAZAP1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	DAZAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAZAP1	0.477523072	0.40545547	0.1651446	73	4	0.01414761	FALSE	12.55319149	DAZAP1	DAZAP1	185.8630137	12.99933702	0	73	0	0.75560632	FALSE	0	DAZAP1	394248	Infinity	0.05559357
790579	taxon:9606	2.69072003	116.5706255	3.56E-04	172084	1902	LY6/PLAUR domain containing 3	gene	biological_process-&-1&-GO:0007160-&&-cell-matrix adhesion-%%-GO:0006501-&&-C-terminal protein lipidation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0046658-&&-anchored component of plasma membrane|molecular_function-&-1&-GO:0043236-&&-laminin binding	G:9606:LYPD3				LYPD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYPD3	0.398113676	0.37164773	0.00821596	72	4	0.00168056	FALSE	1.421052632	LYPD3	LYPD3	47.52777778	1.5	0	72	0	0.71821333	FALSE	0	LYPD3	373892	Infinity	0.02440837
787415	taxon:9606	2.46856783	606.0188962	2.03E-04	163090	1902	taxilin alpha	gene	biological_process-&-1&-GO:0042113-&&-B cell activation-%%-GO:0006887-&&-exocytosis-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019905-&&-syntaxin binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0030372-&&-high molecular weight B cell growth factor receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TXLNA				TXLNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXLNA	0.479521674	0.40509318	0.1010352	72	4	0.006647808	FALSE	9.244444444	TXLNA	TXLNA	121.9857143	9.785442569	0	71	0	0.7552387	FALSE	1	TXLNA	298552	Infinity	0.03646617
787576	taxon:9606	2.41326611	326.4089059	1.55E-04	179148	1902	septin 2	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0031175-&&-neuron projection development-%%-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0097730-&&-non-motile cilium-%%-GO:0031105-&&-septin complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0005930-&&-axoneme-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005938-&&-cell cortex-%%-GO:0000145-&&-exocyst-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0097227-&&-sperm annulus-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0060170-&&-ciliary membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005525-&&-GTP binding	G:9606:SEPT2			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	SEPT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT2	0.488280061	0.41437618	0.13223787	72	4	0.011657865	FALSE	10.57142857	SEPT2	SEPT2	162.4305556	10.81612857	0	72	0	0.76445565	FALSE	0	SEPT2	274930	Infinity	0.04415896
787600	taxon:9606	2.40664881	460.5762088	2.77E-04	179119	1902	nuclear factor, erythroid 2 like 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:1903788-&&-positive regulation of glutathione biosynthetic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:1902037-&&-negative regulation of hematopoietic stem cell differentiation-%%-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0010499-&&-proteasomal ubiquitin-independent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045995-&&-regulation of embryonic development-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:1904753-&&-negative regulation of vascular associated smooth muscle cell migration-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0035690-&&-cellular response to drug-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0007568-&&-aging-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0036091-&&-positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:2000121-&&-regulation of removal of superoxide radicals-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin-%%-GO:0005813-&&-centrosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	G:9606:NFE2L2	NFE2L2	TRUE	KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	NFE2L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFE2L2	0.48095952	0.41551555	0.10837246	72	4	0.008274128	FALSE	9.391304348	NFE2L2	NFE2L2	143.875	10.02439376	0	72	0	0.76555853	FALSE	0	NFE2L2	377938	Infinity	0.03859516
787786	taxon:9606	2.30723176	207.3196253	2.94E-04	178794	1902	protein phosphatase 5 catalytic subunit	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0000165-&&-MAPK cascade-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043278-&&-response to morphine-%%-GO:0016576-&&-histone dephosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:2000324-&&-positive regulation of glucocorticoid receptor signaling pathway-%%-GO:1901215-&&-negative regulation of neuron death|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:1990635-&&-proximal dendrite-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0043531-&&-ADP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding	G:9606:PPP5C			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PPP5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP5C	0.488577521	0.43341983	0.11469979	72	4	0.009735102	FALSE	12.23255814	PPP5C	PPP5C	177.4857143	12.5608705	0	71	0	0.78212804	FALSE	1	PPP5C	403138	Infinity	0.04085675
788073	taxon:9606	2.46179297	107.2861909	6.37E-05	178283	1902	ribosomal protein L29	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0007566-&&-embryo implantation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008201-&&-heparin binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPL29			KEGG-&-1&-hsa03010-&&-Ribosome	RPL29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL29	0.479808555	0.406208	0.3943662	72	4	0.024533965	FALSE	32	RPL29	RPL29	242.3194444	32.51612903	0	72	0	0.75636784	FALSE	0	RPL29	177444	Infinity	0.07171814
792177	taxon:9606	2.48873484	181.5239485	3.36E-04	182475	1902	ADP ribosylation factor 1	gene	biological_process-&-1&-GO:0070142-&&-synaptic vesicle budding-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:1902953-&&-positive regulation of ER to Golgi vesicle-mediated transport-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0055108-&&-Golgi to transport vesicle transport-%%-GO:1903725-&&-regulation of phospholipid metabolic process-%%-GO:0034315-&&-regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0097061-&&-dendritic spine organization-%%-GO:0007015-&&-actin filament organization-%%-GO:1902307-&&-positive regulation of sodium ion transmembrane transport-%%-GO:0002090-&&-regulation of receptor internalization-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0034379-&&-very-low-density lipoprotein particle assembly-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0097212-&&-lysosomal membrane organization-%%-GO:1902824-&&-positive regulation of late endosome to lysosome transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0030137-&&-COPI-coated vesicle-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005770-&&-late endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0031252-&&-cell leading edge-%%-GO:0030017-&&-sarcomere-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:1990583-&&-phospholipase D activator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor	G:9606:ARF1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa05110-&&-Vibrio cholerae infection	ARF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF1	0.467774861	0.40181058	0.0931677	72	4	0.007955336	FALSE	10.14285714	ARF1	ARF1	122.3428571	10.44117647	0	71	0	0.75187753	FALSE	1	ARF1	408312	Infinity	0.03810266
788107	taxon:9606	2.55538049	353.6494645	3.08E-04	178225	1902	pleiotrophin	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0014823-&&-response to activity-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0007507-&&-heart development-%%-GO:0021549-&&-cerebellum development-%%-GO:1904389-&&-rod bipolar cell differentiation-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0044849-&&-estrous cycle-%%-GO:0060221-&&-retinal rod cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030282-&&-bone mineralization-%%-GO:0007399-&&-nervous system development-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0021510-&&-spinal cord development-%%-GO:1904397-&&-negative regulation of neuromuscular junction development-%%-GO:1904373-&&-response to kainic acid-%%-GO:0001889-&&-liver development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:1904391-&&-response to ciliary neurotrophic factor-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0072201-&&-negative regulation of mesenchymal cell proliferation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0030324-&&-lung development-%%-GO:0032570-&&-response to progesterone-%%-GO:1904395-&&-positive regulation of skeletal muscle acetylcholine-gated channel clustering-%%-GO:0021794-&&-thalamus development-%%-GO:1990089-&&-response to nerve growth factor-%%-GO:0042493-&&-response to drug-%%-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0007612-&&-learning-%%-GO:0045446-&&-endothelial cell differentiation-%%-GO:0045837-&&-negative regulation of membrane potential-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0032355-&&-response to estradiol-%%-GO:0071305-&&-cellular response to vitamin D-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005604-&&-basement membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0035374-&&-chondroitin sulfate binding-%%-GO:1904399-&&-heparan sulfate binding-%%-GO:0038085-&&-vascular endothelial growth factor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0035373-&&-chondroitin sulfate proteoglycan binding	G:9606:PTN				PTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTN	0.456459875	0.39133115	0.02939959	72	4	0.005028213	FALSE	5.513513514	PTN	PTN	84.97142857	5.692796093	0	71	0	0.74076992	FALSE	1	PTN	325272	Infinity	0.03067958
792239	taxon:9606	2.46084764	464.9181326	2.11E-04	182364	1902	ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1	gene	biological_process-&-1&-GO:0015986-&&-ATP synthesis coupled proton transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000276-&&-mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism	G:9606:ATP5F1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5F1	0.473156342	0.40636404	0.15571205	72	4	0.008061976	FALSE	8.871794872	ATP5F1	ATP5F1	137.0694444	9.633453965	0	72	0	0.75652539	FALSE	0	ATP5F1	354674	Infinity	0.04053288
792258	taxon:9606	2.56562155	448.4022505	4.48E-05	182339	1902	ATRX, chromatin remodeler	gene	biological_process-&-1&-GO:0070192-&&-chromosome organization involved in meiotic cell cycle-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0031297-&&-replication fork processing-%%-GO:0010571-&&-positive regulation of nuclear cell cycle DNA replication-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006306-&&-DNA methylation-%%-GO:1901581-&&-negative regulation of telomeric RNA transcription from RNA pol II promoter-%%-GO:1904908-&&-negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030900-&&-forebrain development-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0000212-&&-meiotic spindle organization-%%-GO:0007283-&&-spermatogenesis-%%-GO:1900112-&&-regulation of histone H3-K9 trimethylation-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035128-&&-post-embryonic forelimb morphogenesis-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:1901582-&&-positive regulation of telomeric RNA transcription from RNA pol II promoter-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0006310-&&-DNA recombination-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0070198-&&-protein localization to chromosome, telomeric region|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0031933-&&-telomeric heterochromatin-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0070603-&&-SWI/SNF superfamily-type complex-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:1990707-&&-nuclear subtelomeric heterochromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0070087-&&-chromo shadow domain binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0015616-&&-DNA translocase activity-%%-GO:0004386-&&-helicase activity	G:9606:ATRX	ATRX	TRUE		ATRX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATRX	0.465062337	0.3897691	0.30907668	72	4	0.017204124	FALSE	22.94029851	ATRX	ATRX	196.2361111	23.60202603	0	72	0	0.73906307	FALSE	0	ATRX	140170	Infinity	0.07116229
792290	taxon:9606	2.36237593	319.9150871	2.34E-04	182282	1902	cyclin dependent kinase 7	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070985-&&-TFIIK complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity	G:9606:CDK7			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03022-&&-Basal transcription factors-%%-hsa03420-&&-Nucleotide excision repair	CDK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK7	0.488875343	0.42330265	0.14534161	72	4	0.010455515	FALSE	11.5	CDK7	CDK7	171.9428571	11.85840418	0	71	0	0.77293735	FALSE	1	CDK7	354152	Infinity	0.04290349
788262	taxon:9606	2.37655585	626.9031446	1.68E-04	177976	1902	ribophorin II	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0007568-&&-aging-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity	G:9606:RPN2			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RPN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPN2	0.489770992	0.42077698	0.14749609	72	4	0.012962751	FALSE	11.27586207	RPN2	RPN2	190.0277778	12.25550604	0	72	0	0.77057402	FALSE	0	RPN2	335786	Infinity	0.04855964
788362	taxon:9606	2.39105089	285.9012888	2.73E-04	177806	1902	succinate dehydrogenase complex flavoprotein subunit A	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006121-&&-mitochondrial electron transport, succinate to ubiquinone-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0009061-&&-anaerobic respiration-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005749-&&-mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)-%%-GO:0045282-&&-plasma membrane succinate dehydrogenase complex|molecular_function-&-1&-GO:0008177-&&-succinate dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0000104-&&-succinate dehydrogenase activity	G:9606:SDHA			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05016-&&-Huntington disease	SDHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDHA	0.485178463	0.41822615	0.11776213	72	4	0.012731325	FALSE	9.681818182	SDHA	SDHA	189.75	10.02086046	0	72	0	0.76815818	FALSE	0	SDHA	404328	Infinity	0.0497009
792587	taxon:9606	2.58074681	460.3798693	2.83E-04	181760	1902	atrophin 1	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:ATN1				ATN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATN1	0.441629956	0.38748474	0.02898551	72	4	0.003907074	FALSE	5.054054054	ATN1	ATN1	76.5	5.249185642	0	71	0	0.7365422	FALSE	1	ATN1	289920	Infinity	0.02923473
792794	taxon:9606	2.38742713	215.5545976	1.47E-04	181359	1902	eukaryotic translation initiation factor 2 subunit alpha	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0006413-&&-translational initiation-%%-GO:0034605-&&-cellular response to heat-%%-GO:1990737-&&-response to manganese-induced endoplasmic reticulum stress-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0007568-&&-aging-%%-GO:0034644-&&-cellular response to UV-%%-GO:1905098-&&-negative regulation of guanyl-nucleotide exchange factor activity-%%-GO:2000676-&&-positive regulation of type B pancreatic cell apoptotic process-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005850-&&-eukaryotic translation initiation factor 2 complex-%%-GO:0005851-&&-eukaryotic translation initiation factor 2B complex-%%-GO:0044207-&&-translation initiation ternary complex-%%-GO:0043614-&&-multi-eIF complex-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0033290-&&-eukaryotic 48S preinitiation complex-%%-GO:0005634-&&-nucleus-%%-GO:0005840-&&-ribosome-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016020-&&-membrane-%%-GO:0097451-&&-glial limiting end-foot|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:EIF2S1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04210-&&-Apoptosis-%%-hsa05160-&&-Hepatitis C-%%-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	EIF2S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2S1	0.488875343	0.41886095	0.15962441	72	4	0.015421062	FALSE	13.24	EIF2S1	EIF2S1	199.4027778	13.62909666	0	72	0	0.76876214	FALSE	0	EIF2S1	259808	Infinity	0.05192057
788714	taxon:9606	2.5090594	446.2826875	1.79E-04	177135	1902	tropomyosin 2 (beta)	gene	biological_process-&-1&-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction-%%-GO:0007015-&&-actin filament organization-%%-GO:0043462-&&-regulation of ATPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005884-&&-actin filament-%%-GO:0005862-&&-muscle thin filament tropomyosin|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0008307-&&-structural constituent of muscle	G:9606:TPM2	TPM2	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM2	0.474415853	0.39855573	0.11552795	72	4	0.007620079	FALSE	11.5	TPM2	TPM2	119.4714286	12.0360475	0	71	0	0.7484901	FALSE	1	TPM2	256340	Infinity	0.03876954
788875	taxon:9606	2.4610052	300.1540273	3.45E-04	176715	1902	vitronectin	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0097421-&&-liver regeneration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0061302-&&-smooth muscle cell-matrix adhesion-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0006955-&&-immune response-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0051258-&&-protein polymerization-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0048709-&&-oligodendrocyte differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0071062-&&-alphav-beta3 integrin-vitronectin complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005604-&&-basement membrane-%%-GO:0048237-&&-rough endoplasmic reticulum lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0050840-&&-extracellular matrix binding-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005518-&&-collagen binding-%%-GO:0008201-&&-heparin binding-%%-GO:0030247-&&-polysaccharide binding	G:9606:VTN	VTN	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04610-&&-Complement and coagulation cascades-%%-hsa05165-&&-Human papillomavirus infection	VTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VTN	0.47010551	0.40633803	0.1314554	72	4	0.011900711	FALSE	12.70833333	VTN	VTN	137.2083333	13.0936843	0	72	0	0.75649913	FALSE	0	VTN	417776	Infinity	0.04079474
788877	taxon:9606	2.53111706	259.7391841	1.91E-04	176711	1902	Wiskott-Aldrich syndrome	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0008544-&&-epidermis development-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007596-&&-blood coagulation-%%-GO:2000601-&&-positive regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0006952-&&-defense response-%%-GO:0006955-&&-immune response-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0016197-&&-endosomal transport-%%-GO:0042110-&&-T cell activation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0002625-&&-regulation of T cell antigen processing and presentation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0019901-&&-protein kinase binding	G:9606:WAS			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04144-&&-Endocytosis-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05132-&&-Salmonella infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis	WAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WAS	0.441265475	0.39508248	0.08902692	72	4	0.004147896	FALSE	9.194444444	WAS	WAS	100.6857143	9.505361305	0	71	0	0.74481382	FALSE	1	WAS	263474	Infinity	0.03433935
788882	taxon:9606	2.46730739	213.1253102	6.99E-05	176699	1902	nuclear receptor binding SET domain protein 2	gene	biological_process-&-1&-GO:2001032-&&-regulation of double-strand break repair via nonhomologous end joining-%%-GO:0010452-&&-histone H3-K36 methylation-%%-GO:0048298-&&-positive regulation of isotype switching to IgA isotypes-%%-GO:0034770-&&-histone H4-K20 methylation-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0060348-&&-bone development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0003289-&&-atrial septum primum morphogenesis-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0003290-&&-atrial septum secundum morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042799-&&-histone methyltransferase activity (H4-K20 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NSD2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa00310-&&-Lysine degradation	NSD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSD2	0.476813317	0.40530013	0.22939959	72	4	0.017996687	FALSE	19.79032258	NSD2	NSD2	220.2428571	20.26436949	0	71	0	0.75544877	FALSE	1	NSD2	190968	Infinity	0.06561808
789035	taxon:9606	2.36080038	375.3220533	2.38E-04	176318	1902	phosphatidylinositol binding clathrin assembly protein	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:1902963-&&-negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0016197-&&-endosomal transport-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0031623-&&-receptor internalization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0097459-&&-iron ion import into cell-%%-GO:0007409-&&-axonogenesis-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0030097-&&-hemopoiesis-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0035459-&&-cargo loading into vesicle-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0048268-&&-clathrin coat assembly-%%-GO:1902959-&&-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process-%%-GO:1902961-&&-positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0030132-&&-clathrin coat of coated pit-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0032050-&&-clathrin heavy chain binding-%%-GO:0005545-&&-1-phosphatidylinositol binding	G:9606:PICALM				PICALM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PICALM	0.489472078	0.42358516	0.17683881	72	4	0.012274607	FALSE	13.46938776	PICALM	PICALM	191.5277778	13.93865111	0	72	0	0.77319994	FALSE	0	PICALM	353436	Infinity	0.04780483
793163	taxon:9606	2.43752954	91.98749425	5.80E-04	180615	1902	G protein subunit alpha i3	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0051301-&&-cell division-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0006906-&&-vesicle fusion-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0046039-&&-GTP metabolic process-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0042588-&&-zymogen granule-%%-GO:0016020-&&-membrane-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031821-&&-G-protein coupled serotonin receptor binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNAI3	GNAI3	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04916-&&-Melanogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05030-&&-Cocaine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04540-&&-Gap junction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAI3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAI3	0.468321168	0.41025144	0.08240166	72	4	0.005917469	FALSE	8.84	GNAI3	GNAI3	116.9142857	9.317982456	0	71	0	0.76041174	FALSE	1	GNAI3	587576	Infinity	0.0331388
789173	taxon:9606	2.45470301	99.28638533	3.53E-05	176048	1902	histone cluster 1 H2A family member b	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2AB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AB	0.486060606	0.40738126	0.4194617	72	4	0.022196667	FALSE	32.07936508	HIST1H2AB	HIST1H2AB	260.4714286	32.68178511	0	71	0	0.7575495	FALSE	1	HIST1H2AB	141228	Infinity	0.07578453
789167	taxon:9606	2.39057823	397.7437453	3.59E-04	176062	1902	ubiquitin specific peptidase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0050821-&&-protein stabilization-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0048512-&&-circadian behavior-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007049-&&-cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0045475-&&-locomotor rhythm|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0046872-&&-metal ion binding	G:9606:USP2				USP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP2	0.473715298	0.41830884	0.07902973	72	4	0.006594334	FALSE	7.25	USP2	USP2	131.1805556	7.513062169	0	72	0	0.76823696	FALSE	0	USP2	421330	Infinity	0.03436918
793290	taxon:9606	2.36678746	613.8969773	1.43E-04	180370	1902	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	gene	biological_process-&-1&-GO:0035965-&&-cardiolipin acyl-chain remodeling-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0032868-&&-response to insulin-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016507-&&-mitochondrial fatty acid beta-oxidation multienzyme complex|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0003985-&&-acetyl-CoA C-acetyltransferase activity-%%-GO:0016508-&&-long-chain-enoyl-CoA hydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016509-&&-long-chain-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0000062-&&-fatty-acyl-CoA binding-%%-GO:0051287-&&-NAD binding	G:9606:HADHA	HADHA	TRUE	KEGG-&-1&-hsa00410-&&-beta-Alanine metabolism-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00062-&&-Fatty acid elongation-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00071-&&-Fatty acid degradation	HADHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HADHA	0.49644073	0.42251365	0.10054773	72	4	0.013629651	FALSE	8.413793103	HADHA	HADHA	209.7638889	8.923882315	0	72	0	0.77220209	FALSE	0	HADHA	320808	Infinity	0.05287021
793281	taxon:9606	2.45470301	99.28638533	3.53E-05	180382	1902	histone cluster 1 H2A family member e	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2AE			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AE	0.486060606	0.40738126	0.4194617	72	4	0.022196667	FALSE	32.07936508	HIST1H2AE	HIST1H2AE	260.4714286	32.68178511	0	71	0	0.7575495	FALSE	1	HIST1H2AE	141228	Infinity	0.07578453
789689	taxon:9606	2.67181346	53.16586905	5.46E-04	174888	1902	cAMP responsive element binding protein 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006990-&&-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:CREB3			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04916-&&-Melanogenesis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB3	0.403217697	0.37427763	0.02401656	72	4	0.002212953	FALSE	4.933333333	CREB3	CREB3	47.14285714	5.285714286	0	71	0	0.72136442	FALSE	1	CREB3	482756	Infinity	0.02295693
789826	taxon:9606	2.44540728	280.4788038	2.87E-04	174552	1902	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone	gene	biological_process-&-1&-GO:0043947-&&-positive regulation by host of symbiont catalytic activity-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031647-&&-regulation of protein stability|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SUGT1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	SUGT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUGT1	0.475682088	0.40892984	0.06611894	72	4	0.006783489	FALSE	5.421052632	SUGT1	SUGT1	125.9166667	5.570570571	0	72	0	0.75909879	FALSE	0	SUGT1	383736	Infinity	0.03602045
789946	taxon:9606	2.55853159	609.0981007	1.96E-04	174276	1902	NIMA related kinase 6	gene	biological_process-&-1&-GO:0051225-&&-spindle assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0000910-&&-cytokinesis-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2000772-&&-regulation of cellular senescence|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019894-&&-kinesin binding	G:9606:NEK6				NEK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK6	0.455035461	0.39084919	0.03229814	72	4	0.004946222	FALSE	4.818181818	NEK6	NEK6	85.57142857	5.047191168	0	71	0	0.74024474	FALSE	1	NEK6	243830	Infinity	0.03080808
790255	taxon:9606	2.40538837	393.7391803	1.08E-04	173496	1902	La ribonucleoprotein domain family member 1	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0006413-&&-translational initiation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0072752-&&-cellular response to rapamycin-%%-GO:1990928-&&-response to amino acid starvation-%%-GO:0031929-&&-TOR signaling-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0031931-&&-TORC1 complex-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0031369-&&-translation initiation factor binding-%%-GO:0008494-&&-translation activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008190-&&-eukaryotic initiation factor 4E binding	G:9606:LARP1				LARP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LARP1	0.489770992	0.41573328	0.2456964	72	4	0.021296369	FALSE	19.72580645	LARP1	LARP1	240.6527778	20.22136684	0	72	0	0.7657686	FALSE	0	LARP1	243962	Infinity	0.06449583
790352	taxon:9606	2.40381282	209.4141537	6.57E-05	173245	1902	pescadillo ribosomal biogenesis factor 1	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0008283-&&-cell proliferation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007000-&&-nucleolus organization-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000466-&&-maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0070545-&&-PeBoW complex-%%-GO:0016020-&&-membrane-%%-GO:0000793-&&-condensed chromosome-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PES1				PES1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PES1	0.487241798	0.41600577	0.27287785	72	4	0.015592752	FALSE	19.88679245	PES1	PES1	191.2428571	20.28441802	0	71	0	0.7660312	FALSE	1	PES1	152344	Infinity	0.0510215
790865	taxon:9606	2.44162597	387.474945	1.69E-04	170846	1902	5'-3' exoribonuclease 1	gene	biological_process-&-1&-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0071028-&&-nuclear mRNA surveillance-%%-GO:0033574-&&-response to testosterone-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0016075-&&-rRNA catabolic process-%%-GO:0071409-&&-cellular response to cycloheximide|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0004534-&&-5'-3' exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0002151-&&-G-quadruplex RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding	G:9606:XRN1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03018-&&-RNA degradation	XRN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRN1	0.47894894	0.40956314	0.11911469	71	4	0.010510212	FALSE	9.108695652	XRN1	XRN1	160.8450704	9.383660131	0	71	0	0.75972901	FALSE	0	XRN1	287168	Infinity	0.04555321
791276	taxon:9606	2.39057823	377.4873249	2.08E-04	169405	1902	regulatory associated protein of MTOR complex 1	gene	biological_process-&-1&-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0016236-&&-macroautophagy-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0008361-&&-regulation of cell size-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0016049-&&-cell growth-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0031929-&&-TOR signaling-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0032147-&&-activation of protein kinase activity|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005764-&&-lysosome-%%-GO:0031931-&&-TORC1 complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0001156-&&-TFIIIC-class transcription factor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0001031-&&-RNA polymerase III type 2 promoter DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0001030-&&-RNA polymerase III type 1 promoter DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0001032-&&-RNA polymerase III type 3 promoter DNA binding	G:9606:RPTOR			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04136-&&-Autophagy - other-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	RPTOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPTOR	0.48962149	0.41830884	0.11167945	71	4	0.008807152	FALSE	10.3877551	RPTOR	RPTOR	152.7826087	10.82723943	0	70	0	0.76823696	FALSE	1	RPTOR	313960	Infinity	0.03993559
787432	taxon:9606	2.41736253	657.6414704	3.38E-04	179445	1902	galectin 1	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046598-&&-positive regulation of viral entry into host cell-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0002317-&&-plasma cell differentiation-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0034120-&&-positive regulation of erythrocyte aggregation-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0048678-&&-response to axon injury-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0035900-&&-response to isolation stress-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0030395-&&-lactose binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding-%%-GO:0043236-&&-laminin binding	G:9606:LGALS1				LGALS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS1	0.47794994	0.41367399	0.10741688	71	4	0.010537585	FALSE	10.90384615	LGALS1	LGALS1	155.6811594	11.44255781	0	70	0	0.76377291	FALSE	1	LGALS1	420482	Infinity	0.04267554
791692	taxon:9606	2.63242477	382.4041863	2.20E-04	167407	1902	centrosomal protein 44	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000922-&&-spindle pole-%%-GO:0030496-&&-midbody-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP44				CEP44	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP44	0.427277571	0.3798779	0.06156942	71	4	0.002754042	FALSE	4.857142857	CEP44	CEP44	66.71830986	5.014066496	0	71	0	0.72792921	FALSE	0	CEP44	239360	Infinity	0.02872242
787814	taxon:9606	2.4230345	218.0445959	3.10E-04	178755	1902	protein kinase C epsilon	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035669-&&-TRAM-dependent toll-like receptor 4 signaling pathway-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:2001031-&&-positive regulation of cellular glucuronidation-%%-GO:0051301-&&-cell division-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0070257-&&-positive regulation of mucus secretion-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0032230-&&-positive regulation of synaptic transmission, GABAergic-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0007049-&&-cell cycle-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0030168-&&-platelet activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0043278-&&-response to morphine-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0050996-&&-positive regulation of lipid catabolic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0002281-&&-macrophage activation involved in immune response-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0035276-&&-ethanol binding-%%-GO:0005515-&&-protein binding-%%-GO:0003785-&&-actin monomer binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004699-&&-calcium-independent protein kinase C activity-%%-GO:0005524-&&-ATP binding-%%-GO:0030546-&&-receptor activator activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0019899-&&-enzyme binding	G:9606:PRKCE			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04530-&&-Tight junction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04022-&&-cGMP-PKG signaling pathway	PRKCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCE	0.463583815	0.41270564	0.08780904	71	5	0.006231518	FALSE	8.973684211	PRKCE	PRKCE	122.5942029	9.216216216	0	70	0	0.76282758	FALSE	1	PRKCE	377458	Infinity	0.03392339
788011	taxon:9606	2.50228454	373.0231676	1.60E-04	178397	1902	prefoldin subunit 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016272-&&-prefoldin complex|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:PFDN5				PFDN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFDN5	0.471210341	0.39963481	0.0917505	71	4	0.006654219	FALSE	5.146341463	PFDN5	PFDN5	110.6760563	5.344668167	0	71	0	0.74961924	FALSE	0	PFDN5	231222	Infinity	0.03530115
792208	taxon:9606	2.46778005	352.2911038	2.74E-04	182415	1902	argininosuccinate synthase 1	gene	biological_process-&-1&-GO:0000050-&&-urea cycle-%%-GO:0000053-&&-argininosuccinate metabolic process-%%-GO:0006526-&&-arginine biosynthetic process-%%-GO:0006531-&&-aspartate metabolic process-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0000052-&&-citrulline metabolic process-%%-GO:1903038-&&-negative regulation of leukocyte cell-cell adhesion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004055-&&-argininosuccinate synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0016597-&&-amino acid binding	G:9606:ASS1			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa01100-&&-Metabolic pathways	ASS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASS1	0.465737515	0.4052225	0.09633419	71	4	0.006492944	FALSE	9.069767442	ASS1	ASS1	112.7681159	9.407132812	0	70	0	0.75536999	FALSE	1	ASS1	313696	Infinity	0.03369793
788240	taxon:9606	2.35134709	426.1696269	2.45E-04	178020	1902	serine hydroxymethyltransferase 2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0046655-&&-folic acid metabolic process-%%-GO:0006544-&&-glycine metabolic process-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0019264-&&-glycine biosynthetic process from serine-%%-GO:0006564-&&-L-serine biosynthetic process-%%-GO:0034340-&&-response to type I interferon-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0051262-&&-protein tetramerization-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006563-&&-L-serine metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0070552-&&-BRISC complex-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008732-&&-L-allo-threonine aldolase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004372-&&-glycine hydroxymethyltransferase activity-%%-GO:0016597-&&-amino acid binding	G:9606:SHMT2			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa01523-&&-Antifolate resistance-%%-hsa00260-&&-Glycine, serine and threonine metabolism	SHMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHMT2	0.487093835	0.42528813	0.10869565	71	4	0.011448891	FALSE	9.441860465	SHMT2	SHMT2	188.2173913	9.824550295	0	70	0	0.77477548	FALSE	1	SHMT2	420938	Infinity	0.04625711
792473	taxon:9606	2.47124626	522.8995556	1.65E-04	181964	1902	BCL2 associated athanogene 1	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding	G:9606:BAG1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	BAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG1	0.475682088	0.40465413	0.10342052	71	4	0.007537861	FALSE	7.93877551	BAG1	BAG1	127.4788732	8.313627347	0	71	0	0.75479229	FALSE	0	BAG1	262424	Infinity	0.03843817
788578	taxon:9606	2.49834568	118.9901585	2.28E-04	177405	1902	transaldolase 1	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0009052-&&-pentose-phosphate shunt, non-oxidative branch-%%-GO:0005999-&&-xylulose biosynthetic process-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004801-&&-sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0048029-&&-monosaccharide binding	G:9606:TALDO1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00030-&&-Pentose phosphate pathway	TALDO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TALDO1	0.466008135	0.40026487	0.11466326	71	4	0.006816035	FALSE	10	TALDO1	TALDO1	122.1014493	10.3030303	0	70	0	0.75027572	FALSE	1	TALDO1	327286	Infinity	0.03859234
792695	taxon:9606	2.36410903	624.9884685	2.22E-04	181548	1902	DEAD-box helicase 6	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006417-&&-regulation of translation-%%-GO:0019074-&&-viral RNA genome packaging-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|cellular_component-&-1&-GO:0001520-&&-outer dense fiber-%%-GO:0000792-&&-heterochromatin-%%-GO:0043186-&&-P granule-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0097227-&&-sperm annulus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004386-&&-helicase activity-%%-GO:0045296-&&-cadherin binding	G:9606:DDX6			KEGG-&-1&-hsa03018-&&-RNA degradation	DDX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX6	0.488131467	0.42299234	0.1110664	71	4	0.013118749	FALSE	8.822222222	DDX6	DDX6	203.1830986	9.222537879	0	71	0	0.7726485	FALSE	0	DDX6	410588	Infinity	0.05099843
788641	taxon:9606	2.33480384	590.2797495	1.76E-04	177269	1902	aminoacyl tRNA synthetase complex interacting multifunctional protein 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0060510-&&-Type II pneumocyte differentiation-%%-GO:0031398-&&-positive regulation of protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AIMP2				AIMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIMP2	0.495061728	0.4283015	0.12659847	71	4	0.010467271	FALSE	10.94339623	AIMP2	AIMP2	169.0869565	11.54289961	0	70	0	0.77753269	FALSE	1	AIMP2	308156	Infinity	0.0404964
792870	taxon:9606	2.47313692	458.6713465	2.12E-04	181245	1902	electron transfer flavoprotein alpha subunit	gene	biological_process-&-1&-GO:0022904-&&-respiratory electron transport chain-%%-GO:0033539-&&-fatty acid beta-oxidation using acyl-CoA dehydrogenase|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0005515-&&-protein binding	G:9606:ETFA				ETFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETFA	0.471903501	0.40434478	0.09859155	71	4	0.007099261	FALSE	7.139534884	ETFA	ETFA	126.7183099	7.604462024	0	71	0	0.75447718	FALSE	0	ETFA	296866	Infinity	0.03827802
792938	taxon:9606	2.48148732	198.4317288	2.64E-04	181112	1902	protein tyrosine kinase 2 beta	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:2000538-&&-positive regulation of B cell chemotaxis-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0045087-&&-innate immune response-%%-GO:0002315-&&-marginal zone B cell differentiation-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0001556-&&-oocyte maturation-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:0009749-&&-response to glucose-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0030826-&&-regulation of cGMP biosynthetic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010656-&&-negative regulation of muscle cell apoptotic process-%%-GO:0051592-&&-response to calcium ion-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0042220-&&-response to cocaine-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0042976-&&-activation of Janus kinase activity-%%-GO:0043534-&&-blood vessel endothelial cell migration-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0051591-&&-response to cAMP-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0031175-&&-neuron projection development-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0009725-&&-response to hormone-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007172-&&-signal complex assembly-%%-GO:0032960-&&-regulation of inositol trisphosphate biosynthetic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0010226-&&-response to lithium ion-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045453-&&-bone resorption-%%-GO:0006968-&&-cellular defense response-%%-GO:0045471-&&-response to ethanol-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0010758-&&-regulation of macrophage chemotaxis-%%-GO:0006950-&&-response to stress-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0014009-&&-glial cell proliferation-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:2000058-&&-regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0006915-&&-apoptotic process-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0010752-&&-regulation of cGMP-mediated signaling-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001525-&&-angiogenesis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046330-&&-positive regulation of JNK cascade|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0043197-&&-dendritic spine-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030425-&&-dendrite-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030027-&&-lamellipodium-%%-GO:0030426-&&-growth cone-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0097440-&&-apical dendrite-%%-GO:0043025-&&-neuronal cell body-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043423-&&-3-phosphoinositide-dependent protein kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004972-&&-NMDA glutamate receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0032403-&&-protein complex binding	G:9606:PTK2B			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection	PTK2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTK2B	0.446796657	0.40298413	0.17604433	71	4	0.005054933	FALSE	16.66666667	PTK2B	PTK2B	121	17.39951785	0	70	0	0.75308545	FALSE	1	PTK2B	316696	Infinity	0.03715771
792989	taxon:9606	2.40066173	474.8774874	2.58E-04	181039	1902	filamin C	gene	biological_process-&-1&-GO:0048747-&&-muscle fiber development-%%-GO:0034329-&&-cell junction assembly|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0042383-&&-sarcolemma-%%-GO:0043034-&&-costamere-%%-GO:0016528-&&-sarcoplasm|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0030506-&&-ankyrin binding	G:9606:FLNC			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	FLNC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLNC	0.48783455	0.41655181	0.08289738	71	4	0.010607919	FALSE	7.956521739	FLNC	FLNC	164.1126761	8.231356245	0	71	0	0.76655638	FALSE	0	FLNC	390144	Infinity	0.04378044
789000	taxon:9606	2.54009768	292.8691276	2.12E-04	176431	1902	YEATS domain containing 4	gene	biological_process-&-1&-GO:0007067-&&-mitotic nuclear division-%%-GO:0040008-&&-regulation of growth-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016363-&&-nuclear matrix-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:YEATS4				YEATS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YEATS4	0.456200228	0.39368565	0.10623742	71	4	0.005640642	FALSE	4.974358974	YEATS4	YEATS4	105.2676056	5.105263158	0	71	0	0.74331705	FALSE	0	YEATS4	281638	Infinity	0.03631322
793168	taxon:9606	2.39089334	451.3035485	4.87E-04	180606	1902	G protein subunit beta 1	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006457-&&-protein folding-%%-GO:0007165-&&-signal transduction-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:0050909-&&-sensory perception of taste-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0008283-&&-cell proliferation-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0071870-&&-cellular response to catecholamine stimulus-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0016056-&&-rhodopsin mediated signaling pathway-%%-GO:0010659-&&-cardiac muscle cell apoptotic process-%%-GO:0030168-&&-platelet activation-%%-GO:0071377-&&-cellular response to glucagon stimulus|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0042622-&&-photoreceptor outer segment membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body-%%-GO:0097381-&&-photoreceptor disc membrane-%%-GO:0005622-&&-intracellular-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0047391-&&-alkylglycerophosphoethanolamine phosphodiesterase activity	G:9606:GNB1	GNB1	TRUE	KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04744-&&-Phototransduction-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa04740-&&-Olfactory transduction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNB1	0.484445787	0.41825371	0.07042254	71	4	0.00841715	FALSE	5.840909091	GNB1	GNB1	143.943662	6.519198474	0	71	0	0.76818444	FALSE	0	GNB1	577450	Infinity	0.0377385
793223	taxon:9606	2.55081141	281.2517577	4.00E-04	180507	1902	heat shock protein family B (small) member 2	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008047-&&-enzyme activator activity-%%-GO:0005515-&&-protein binding	G:9606:HSPB2			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	HSPB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPB2	0.459204123	0.39203212	0.04262575	71	4	0.005916835	FALSE	5.918918919	HSPB2	HSPB2	90.07246377	6.155525847	0	70	0	0.74153143	FALSE	1	HSPB2	440682	Infinity	0.03206082
789209	taxon:9606	2.37340476	391.8179252	1.44E-04	175998	1902	COP9 signalosome subunit 3	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0000338-&&-protein deneddylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0009416-&&-response to light stimulus-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS3				COPS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS3	0.490820073	0.42133563	0.2173913	71	4	0.012164388	FALSE	15.98	COPS3	COPS3	188.057971	16.9409155	0	70	0	0.77109921	FALSE	1	COPS3	289482	Infinity	0.04782019
789609	taxon:9606	2.40838191	418.8135008	1.81E-04	175060	1902	mediator complex subunit 12	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:1990403-&&-embryonic brain development-%%-GO:0007492-&&-endoderm development-%%-GO:0007507-&&-heart development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0048702-&&-embryonic neurocranium morphogenesis-%%-GO:0014044-&&-Schwann cell development-%%-GO:0021510-&&-spinal cord development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0001843-&&-neural tube closure-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0090245-&&-axis elongation involved in somitogenesis-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004872-&&-receptor activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:MED12			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED12	0.480671262	0.41521654	0.2084399	71	4	0.006994478	FALSE	10.41860465	MED12	MED12	145.0724638	11.22210826	0	70	0	0.76526968	FALSE	1	MED12	316648	Infinity	0.03900726
789764	taxon:9606	2.35213487	646.2274708	2.21E-04	174743	1902	protein disulfide isomerase family A member 6	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PDIA6			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	PDIA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIA6	0.492628993	0.42514569	0.11589537	71	4	0.015438417	FALSE	8.944444444	PDIA6	PDIA6	226.7042254	9.497906294	0	71	0	0.77464419	FALSE	0	PDIA6	441776	Infinity	0.05590386
789832	taxon:9606	2.38837246	454.8599727	1.02E-04	174547	1902	transcription elongation regulator 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:TCERG1			KEGG-&-1&-hsa03040-&&-Spliceosome	TCERG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCERG1	0.492628993	0.41869516	0.17625755	71	4	0.015765568	FALSE	14.2	TCERG1	TCERG1	203.6619718	14.63230732	0	71	0	0.76860459	FALSE	0	TCERG1	237804	Infinity	0.05310895
790070	taxon:9606	2.33054987	614.0689284	1.35E-04	173955	1902	serine/threonine kinase receptor associated protein	gene	biological_process-&-1&-GO:0030277-&&-maintenance of gastrointestinal epithelium-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:STRAP			KEGG-&-1&-hsa03013-&&-RNA transport	STRAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STRAP	0.497210167	0.42908329	0.1172208	71	4	0.012610079	FALSE	10	STRAP	STRAP	206.826087	10.61097465	0	70	0	0.77824169	FALSE	1	STRAP	319874	Infinity	0.04906906
790441	taxon:9606	2.57286907	82.6339834	3.99E-04	172941	1902	NUFIP1, FMR1 interacting protein 1	gene	biological_process-&-1&-GO:0000492-&&-box C/D snoRNP assembly-%%-GO:0006396-&&-RNA processing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051259-&&-protein oligomerization|cellular_component-&-1&-GO:0070761-&&-pre-snoRNP complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0016363-&&-nuclear matrix-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0005726-&&-perichromatin fibrils-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:NUFIP1				NUFIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUFIP1	0.436462585	0.38867116	0.02514919	71	4	0.0037114	FALSE	5.263157895	NUFIP1	NUFIP1	74.97101449	5.555555556	0	70	0	0.73785515	FALSE	1	NUFIP1	418128	Infinity	0.02788651
790785	taxon:9606	2.47408224	177.0459129	3.31E-04	171218	1902	ECSIT signalling integrator	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051341-&&-regulation of oxidoreductase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016651-&&-oxidoreductase activity, acting on NAD(P)H-%%-GO:0005515-&&-protein binding	G:9606:ECSIT			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	ECSIT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECSIT	0.455940875	0.40419028	0.08691835	70	4	0.004278142	FALSE	6.233333333	ECSIT	ECSIT	96.76470588	6.448275862	0	69	0	0.75431963	FALSE	1	ECSIT	334846	Infinity	0.02942967
790885	taxon:9606	2.54356389	152.8051755	2.59E-05	170777	1902	ribosomal protein S27 like	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006412-&&-translation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008494-&&-translation activator activity-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RPS27L			KEGG-&-1&-hsa03010-&&-Ribosome	RPS27L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS27L	0.47010551	0.39314916	0.52960663	70	4	0.022947606	FALSE	37.91176471	RPS27L	RPS27L	180.6571429	38.5835543	0	70	0	0.74273935	FALSE	0	RPS27L	71654	Infinity	0.06269648
791035	taxon:9606	2.62564991	323.2390099	1.73E-04	170291	1902	nuclear receptor binding SET domain protein 3	gene	biological_process-&-1&-GO:0016571-&&-histone methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:NSD3			KEGG-&-1&-hsa00310-&&-Lysine degradation	NSD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSD3	0.436581383	0.38085809	0.21035197	70	4	0.01357034	FALSE	17.66037736	NSD3	NSD3	173.8428571	18.14266667	0	70	0	0.72905835	FALSE	0	NSD3	331174	Infinity	0.07342193
791078	taxon:9606	2.52134867	254.8363857	1.86E-04	170127	1902	developmental pluripotency associated 4	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0060484-&&-lung-associated mesenchyme development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DPPA4				DPPA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPPA4	0.467365967	0.39661314	0.09086918	70	4	0.006641343	FALSE	8.975	DPPA4	DPPA4	109.3235294	9.218362283	0	69	0	0.74644189	FALSE	1	DPPA4	277850	Infinity	0.03630515
787379	taxon:9606	2.37482275	429.5203443	8.11E-05	179528	1902	myosin heavy chain 10	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0007512-&&-adult heart development-%%-GO:0001764-&&-neuron migration-%%-GO:0021680-&&-cerebellar Purkinje cell layer development-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0001778-&&-plasma membrane repair-%%-GO:0007411-&&-axon guidance-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0008283-&&-cell proliferation-%%-GO:0098885-&&-modification of postsynaptic actin cytoskeleton-%%-GO:0007155-&&-cell adhesion-%%-GO:0021678-&&-third ventricle development-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0003279-&&-cardiac septum development-%%-GO:0007097-&&-nuclear migration-%%-GO:0035904-&&-aorta development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0021592-&&-fourth ventricle development-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0006887-&&-exocytosis-%%-GO:0060976-&&-coronary vasculature development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0016460-&&-myosin II complex-%%-GO:0042641-&&-actomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0016459-&&-myosin complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0097513-&&-myosin II filament-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0030027-&&-lamellipodium-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043531-&&-ADP binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0003779-&&-actin binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MYH10			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYH10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH10	0.492175514	0.42108406	0.1320911	70	4	0.015360747	FALSE	9.950819672	MYH10	MYH10	219.6571429	10.39354601	0	70	0	0.77086287	FALSE	0	MYH10	230898	Infinity	0.05614227
791477	taxon:9606	2.55664093	352.1833058	3.42E-04	168475	1902	NGG1 interacting factor 3 like 1	gene	biological_process-&-1&-GO:0030182-&&-neuron differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding	G:9606:NIF3L1				NIF3L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NIF3L1	0.446796657	0.39113823	0.07155399	70	4	0.003992496	FALSE	5.676470588	NIF3L1	NIF3L1	82.79411765	5.857386364	0	69	0	0.74055984	FALSE	1	NIF3L1	374352	Infinity	0.0296544
787478	taxon:9606	2.36741768	389.3602467	2.15E-04	179356	1902	ataxin 3	gene	biological_process-&-1&-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1904379-&&-protein localization to cytosolic proteasome complex involved in ERAD pathway-%%-GO:1904294-&&-positive regulation of ERAD pathway-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0010810-&&-regulation of cell-substrate adhesion-%%-GO:0071218-&&-cellular response to misfolded protein-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0034605-&&-cellular response to heat-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0042405-&&-nuclear inclusion body|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:ATXN3			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	ATXN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN3	0.487241798	0.42240117	0.11369622	70	4	0.009546751	FALSE	11.63461538	ATXN3	ATXN3	169.3382353	12.13432746	0	69	0	0.77209705	FALSE	1	ATXN3	333276	Infinity	0.04277974
791818	taxon:9606	2.57318418	381.9459445	1.09E-04	166711	1902	tripartite motif containing 55	gene	biological_process-&-1&-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM55				TRIM55	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM55	0.461317227	0.38862356	0.10623354	70	4	0.007812951	FALSE	10.27083333	TRIM55	TRIM55	105.8088235	10.76296648	0	69	0	0.73780264	FALSE	1	TRIM55	170276	Infinity	0.03910156
787734	taxon:9606	2.51221049	440.0480693	1.78E-04	178856	1902	RNA polymerase II subunit G	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0000291-&&-nuclear-transcribed mRNA catabolic process, exonucleolytic-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:POLR2G			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2G	0.465332173	0.39805582	0.17471466	70	4	0.005145515	FALSE	9.771428571	POLR2G	POLR2G	109.6764706	10.26240262	0	69	0	0.74796492	FALSE	1	POLR2G	268358	Infinity	0.0356425
792254	taxon:9606	2.39530487	661.2207348	2.00E-04	182346	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	gene	biological_process-&-1&-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0015992-&&-proton transport-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0016887-&&-ATPase activity-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005215-&&-transporter activity	G:9606:ATP5O			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5O	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5O	0.481681682	0.41748339	0.1515528	70	4	0.011372699	FALSE	10.10638298	ATP5O	ATP5O	181.9571429	10.95710596	0	70	0	0.76744919	FALSE	0	ATP5O	396218	Infinity	0.04798206
788222	taxon:9606	2.33874271	277.8816719	8.56E-05	178052	1902	replication factor C subunit 4	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0006271-&&-DNA strand elongation involved in DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1900264-&&-positive regulation of DNA-directed DNA polymerase activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031390-&&-Ctf18 RFC-like complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0003689-&&-DNA clamp loader activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:RFC4			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC4	0.496133622	0.42758017	0.23395445	70	4	0.015297195	FALSE	14.44444444	RFC4	RFC4	223.7571429	14.79627109	0	70	0	0.77687621	FALSE	0	RFC4	231802	Infinity	0.0538525
792685	taxon:9606	2.51898535	398.8712431	1.05E-04	181560	1902	damage specific DNA binding protein 2	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006281-&&-DNA repair-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0009411-&&-response to UV-%%-GO:0006290-&&-pyrimidine dimer repair-%%-GO:0070914-&&-UV-damage excision repair|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:DDB2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05216-&&-Thyroid cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DDB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDB2	0.471071953	0.39698524	0.1286216	70	4	0.01027228	FALSE	11.39622642	DDB2	DDB2	137.0147059	12.06664652	0	69	0	0.74683578	FALSE	1	DDB2	180602	Infinity	0.04517015
788695	taxon:9606	2.45486056	230.7785889	2.20E-04	177170	1902	TNF alpha induced protein 3	gene	biological_process-&-1&-GO:0072573-&&-tolerance induction to lipopolysaccharide-%%-GO:0006915-&&-apoptotic process-%%-GO:0061043-&&-regulation of vascular wound healing-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0070433-&&-negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0070429-&&-negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0072666-&&-establishment of protein localization to vacuole-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0035871-&&-protein K11-linked deubiquitination-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0050691-&&-regulation of defense response to virus by host-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0034140-&&-negative regulation of toll-like receptor 3 signaling pathway-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:2000349-&&-negative regulation of CD40 signaling pathway-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0034144-&&-negative regulation of toll-like receptor 4 signaling pathway-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0034136-&&-negative regulation of toll-like receptor 2 signaling pathway-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050869-&&-negative regulation of B cell activation-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0051259-&&-protein oligomerization-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0001922-&&-B-1 B cell homeostasis-%%-GO:0071947-&&-protein deubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0090291-&&-negative regulation of osteoclast proliferation-%%-GO:0002677-&&-negative regulation of chronic inflammatory response-%%-GO:0034148-&&-negative regulation of toll-like receptor 5 signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005764-&&-lysosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0002020-&&-protease binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0043621-&&-protein self-association-%%-GO:0008270-&&-zinc ion binding	G:9606:TNFAIP3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis	TNFAIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFAIP3	0.470933647	0.40735511	0.14223003	70	4	0.00766211	FALSE	13.5952381	TNFAIP3	TNFAIP3	138.6764706	14.04475825	0	69	0	0.75752324	FALSE	1	TNFAIP3	299230	Infinity	0.04055089
788757	taxon:9606	2.44036553	347.5740889	2.19E-04	176996	1902	tripartite motif containing 25	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045087-&&-innate immune response-%%-GO:0036503-&&-ERAD pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0033280-&&-response to vitamin D-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0043627-&&-response to estrogen-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:1902186-&&-regulation of viral release from host cell-%%-GO:0046596-&&-regulation of viral entry into host cell-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0051607-&&-defense response to virus-%%-GO:0019985-&&-translesion synthesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0045296-&&-cadherin binding	G:9606:TRIM25			KEGG-&-1&-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A	TRIM25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM25	0.487389851	0.40977468	0.08955224	70	4	0.010060491	FALSE	9.369565217	TRIM25	TRIM25	161.2058824	9.66343744	0	69	0	0.75993908	FALSE	1	TRIM25	315170	Infinity	0.04583298
789144	taxon:9606	2.41673231	327.4045739	2.38E-04	176119	1902	suppressor of cytokine signaling 3	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0060708-&&-spongiotrophoblast differentiation-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042512-&&-negative regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0060707-&&-trophoblast giant cell differentiation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0040008-&&-regulation of growth-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:SOCS3	SOCS3	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04931-&&-Insulin resistance-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS3	0.470795421	0.41378186	0.0989648	70	4	0.006228113	FALSE	8.390243902	SOCS3	SOCS3	125.7571429	8.613888889	0	70	0	0.76387795	FALSE	0	SOCS3	347996	Infinity	0.03447154
793329	taxon:9606	2.57602017	296.3962375	2.27E-04	180314	1902	histidine triad nucleotide binding protein 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0009154-&&-purine ribonucleotide catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0016787-&&-hydrolase activity	G:9606:HINT1				HINT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HINT1	0.458285714	0.38819572	0.13388938	70	4	0.005835317	FALSE	10.2195122	HINT1	HINT1	99.32352941	10.61654539	0	69	0	0.73732997	FALSE	1	HINT1	302774	Infinity	0.03719432
789464	taxon:9606	2.5174098	235.3688338	1.81E-04	175414	1902	VPS26, retromer complex component A	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0030906-&&-retromer, cargo-selective complex-%%-GO:0030904-&&-retromer complex-%%-GO:0005764-&&-lysosome-%%-GO:0005768-&&-endosome-%%-GO:0031982-&&-vesicle-%%-GO:0010008-&&-endosome membrane-%%-GO:0097422-&&-tubular endosome|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:VPS26A			KEGG-&-1&-hsa04144-&&-Endocytosis	VPS26A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS26A	0.459335624	0.3972337	0.06892011	70	4	0.005110042	FALSE	6.46875	VPS26A	VPS26A	100.4558824	6.710872162	0	69	0	0.74709837	FALSE	1	VPS26A	225316	Infinity	0.0331587
789765	taxon:9606	2.30092957	350.5135471	1.90E-04	174742	1902	TNF receptor associated protein 1	gene	biological_process-&-1&-GO:0006950-&&-response to stress-%%-GO:1903751-&&-negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:1903427-&&-negative regulation of reactive oxygen species biosynthetic process-%%-GO:0009386-&&-translational attenuation-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:1901856-&&-negative regulation of cellular respiration|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005811-&&-lipid particle-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:TRAP1				TRAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAP1	0.496748219	0.43460696	0.13126294	70	4	0.014552379	FALSE	11.15384615	TRAP1	TRAP1	217.5142857	11.46838194	0	70	0	0.7831784	FALSE	0	TRAP1	348204	Infinity	0.04965753
789803	taxon:9606	2.57602017	546.0655116	2.90E-04	174631	1902	sprouty RTK signaling antagonist 2	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0060437-&&-lung growth-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0051387-&&-negative regulation of neurotrophin TRK receptor signaling pathway-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0045165-&&-cell fate commitment-%%-GO:0031345-&&-negative regulation of cell projection organization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity	G:9606:SPRY2			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	SPRY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRY2	0.426822778	0.38819572	0.08823529	70	4	0.003095663	FALSE	7.121212121	SPRY2	SPRY2	83	7.757727743	0	69	0	0.73732997	FALSE	1	SPRY2	326970	Infinity	0.03123893
790035	taxon:9606	2.44477706	359.6964317	2.64E-04	174050	1902	WW domain containing E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007417-&&-central nervous system development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:WWP1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis	WWP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWP1	0.473715298	0.40903525	0.07111501	70	4	0.006003869	FALSE	8.071428571	WWP1	WWP1	122.7352941	8.351670994	0	69	0	0.75920382	FALSE	1	WWP1	337436	Infinity	0.03521472
790307	taxon:9606	2.49440681	778.8674661	1.88E-04	173367	1902	MOB family member 4, phocein	gene	biological_process-&-1&-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:MOB4				MOB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOB4	0.469692533	0.40089692	0.09979296	70	4	0.006624113	FALSE	5.918367347	MOB4	MOB4	114.2285714	6.25887581	0	70	0	0.7509322	FALSE	0	MOB4	257510	Infinity	0.03586922
790375	taxon:9606	2.39577753	172.3448149	9.00E-05	173187	1902	GTP binding protein 4	gene	biological_process-&-1&-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0033342-&&-negative regulation of collagen binding-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0050821-&&-protein stabilization-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030336-&&-negative regulation of cell migration|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0003723-&&-RNA binding	G:9606:GTPBP4			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	GTPBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTPBP4	0.48783455	0.41740103	0.29482402	70	4	0.017793456	FALSE	19.80769231	GTPBP4	GTPBP4	225.4857143	20.26270053	0	70	0	0.76737041	FALSE	0	GTPBP4	190378	Infinity	0.05939335
790391	taxon:9606	2.46132031	269.7920794	1.89E-04	173129	1902	nucleoporin 62	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0042306-&&-regulation of protein import into nucleus-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0071426-&&-ribonucleoprotein complex export from nucleus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0008219-&&-cell death-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007569-&&-cell aging-%%-GO:0016925-&&-protein sumoylation-%%-GO:0019083-&&-viral transcription-%%-GO:0016032-&&-viral process-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000922-&&-spindle pole-%%-GO:0044613-&&-nuclear pore central transport channel-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0046930-&&-pore complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005642-&&-annulate lamellae-%%-GO:0090543-&&-Flemming body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0031074-&&-nucleocytoplasmic shuttling complex|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0051425-&&-PTB domain binding-%%-GO:0051879-&&-Hsp90 protein binding	G:9606:NUP62			KEGG-&-1&-hsa03013-&&-RNA transport	NUP62	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP62	0.479952124	0.40628601	0.09306409	70	4	0.009980639	FALSE	9.926829268	NUP62	NUP62	145.8823529	10.19444444	0	69	0	0.75644662	FALSE	1	NUP62	283214	Infinity	0.0429941
790453	taxon:9606	2.51000473	346.2713898	1.48E-04	172810	1902	UPF2 regulator of nonsense transcripts homolog (yeast)	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0001889-&&-liver development-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome-%%-GO:0035145-&&-exon-exon junction complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding	G:9606:UPF2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	UPF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPF2	0.464792814	0.39840562	0.06760316	70	4	0.007653623	FALSE	6.756097561	UPF2	UPF2	107.1470588	6.979093567	0	69	0	0.74833255	FALSE	1	UPF2	204762	Infinity	0.03474199
790914	taxon:9606	2.6615724	345.8666599	2.21E-04	170710	1902	ubiquitin fold modifier 1	gene	biological_process-&-1&-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071569-&&-protein ufmylation-%%-GO:1990592-&&-protein K69-linked ufmylation-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UFM1				UFM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UFM1	0.426368953	0.37571775	0.07161125	69	4	0.003834403	FALSE	5.128205128	UFM1	UFM1	76.85507246	5.271843614	0	69	0	0.72307127	FALSE	0	UFM1	256652	Infinity	0.03559635
787093	taxon:9606	2.38002206	272.2614194	8.74E-05	180064	1902	IK cytokine, down-regulator of HLA II	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:IK				IK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IK	0.48783455	0.42016417	0.20759837	69	4	0.013664058	FALSE	16.94545455	IK	IK	195.7910448	17.44803216	0	68	0	0.76999632	FALSE	1	IK	200402	Infinity	0.05027252
791283	taxon:9606	2.55742871	285.1684297	1.66E-04	169370	1902	centrosomal protein 126	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0097546-&&-ciliary base|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP126				CEP126	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP126	0.452340666	0.39101774	0.06095482	69	4	0.005346109	FALSE	4.833333333	CEP126	CEP126	94.11594203	5.030952381	0	69	0	0.74042855	FALSE	0	CEP126	228012	Infinity	0.03362464
787269	taxon:9606	2.37025366	422.6588022	1.19E-04	179772	1902	lysyl-tRNA synthetase	gene	biological_process-&-1&-GO:0015966-&&-diadenosine tetraphosphate biosynthetic process-%%-GO:0006430-&&-lysyl-tRNA aminoacylation-%%-GO:0008033-&&-tRNA processing-%%-GO:0016032-&&-viral process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004824-&&-lysine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0016597-&&-amino acid binding	G:9606:KARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	KARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KARS	0.492326581	0.42189577	0.15984655	69	4	0.012997662	FALSE	11.17647059	KARS	KARS	187.2463768	11.61981842	0	69	0	0.77162439	FALSE	0	KARS	234042	Infinity	0.04749667
791390	taxon:9606	2.41625965	290.5797895	7.45E-05	168828	1902	RNA binding motif protein 25	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM25			KEGG-&-1&-hsa03040-&&-Spliceosome	RBM25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM25	0.487537994	0.41386281	0.23401535	69	4	0.017214336	FALSE	17.73333333	RBM25	RBM25	231.3768116	18.16778638	0	69	0	0.76395672	FALSE	0	RBM25	205994	Infinity	0.06307588
787396	taxon:9606	2.38411848	492.7311148	1.68E-04	179501	1902	protein phosphatase 1 regulatory subunit 12A	gene	biological_process-&-1&-GO:0035508-&&-positive regulation of myosin-light-chain-phosphatase activity-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0035507-&&-regulation of myosin-light-chain-phosphatase activity-%%-GO:0035690-&&-cellular response to drug-%%-GO:0007165-&&-signal transduction-%%-GO:0051297-&&-centrosome organization-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0031672-&&-A band-%%-GO:0000776-&&-kinetochore-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043292-&&-contractile fiber-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0019208-&&-phosphatase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004857-&&-enzyme inhibitor activity	G:9606:PPP1R12A			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP1R12A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R12A	0.488875343	0.41944224	0.13256607	69	4	0.010129682	FALSE	9.895833333	PPP1R12A	PPP1R12A	171.6666667	10.38205343	0	69	0	0.76931359	FALSE	0	PPP1R12A	311158	Infinity	0.04432813
787566	taxon:9606	2.39010556	593.3033998	2.33E-04	179161	1902	NADH:ubiquinone oxidoreductase core subunit S1	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0045333-&&-cellular respiration|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding	G:9606:NDUFS1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS1	0.481392557	0.41839156	0.20417732	69	4	0.009052041	FALSE	9.048780488	NDUFS1	NDUFS1	174.5652174	9.989744116	0	69	0	0.76831574	FALSE	0	NDUFS1	434674	Infinity	0.04548768
787674	taxon:9606	2.40743658	246.5821239	2.70E-04	178969	1902	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0044029-&&-hypomethylation of CpG island-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0043276-&&-anoikis-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0043457-&&-regulation of cellular respiration-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001944-&&-vasculature development-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:2000270-&&-negative regulation of fibroblast apoptotic process-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0001889-&&-liver development-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0097009-&&-energy homeostasis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0038028-&&-insulin receptor signaling pathway via phosphatidylinositol 3-kinase-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:2000653-&&-regulation of genetic imprinting-%%-GO:0001525-&&-angiogenesis-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0016310-&&-phosphorylation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005943-&&-phosphatidylinositol 3-kinase complex, class IA-%%-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0035004-&&-phosphatidylinositol 3-kinase activity-%%-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PIK3CA			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3CA	0.48009578	0.41537958	0.08653026	69	4	0.006699665	FALSE	8.384615385	PIK3CA	PIK3CA	132.884058	8.661897391	0	69	0	0.76542724	FALSE	0	PIK3CA	356736	Infinity	0.03580586
787929	taxon:9606	2.54183079	320.1389402	7.46E-05	178568	1902	origin recognition complex subunit 2	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0000808-&&-origin recognition complex-%%-GO:0000939-&&-condensed chromosome inner kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0000792-&&-heterochromatin|molecular_function-&-1&-GO:0003688-&&-DNA replication origin binding-%%-GO:0005515-&&-protein binding	G:9606:ORC2			KEGG-&-1&-hsa04110-&&-Cell cycle	ORC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ORC2	0.4685948	0.39341722	0.21483492	69	4	0.013047602	FALSE	14.90384615	ORC2	ORC2	168.6268657	15.32160592	0	68	0	0.7430282	FALSE	1	ORC2	172524	Infinity	0.05799177
788069	taxon:9606	2.35985505	105.5123896	5.42E-05	178284	1902	ribosomal protein L28	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0030425-&&-dendrite-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL28			KEGG-&-1&-hsa03010-&&-Ribosome	RPL28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL28	0.494603762	0.42375484	0.4799659	69	4	0.025534054	FALSE	35.1875	RPL28	RPL28	267.0289855	35.74603175	0	69	0	0.77335749	FALSE	0	RPL28	166892	Infinity	0.06646751
788366	taxon:9606	2.46305341	314.3467011	1.28E-04	177793	1902	signal recognition particle 14	gene	biological_process-&-1&-GO:0045047-&&-protein targeting to ER-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0042493-&&-response to drug-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0006613-&&-cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005786-&&-signal recognition particle, endoplasmic reticulum targeting-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008312-&&-7S RNA binding-%%-GO:0030942-&&-endoplasmic reticulum signal peptide binding-%%-GO:0005515-&&-protein binding	G:9606:SRP14			KEGG-&-1&-hsa03060-&&-Protein export	SRP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRP14	0.478520286	0.40600013	0.1543052	69	4	0.015582587	FALSE	11.73584906	SRP14	SRP14	197.7971015	12.12105246	0	69	0	0.75615776	FALSE	0	SRP14	274652	Infinity	0.05865459
788380	taxon:9606	2.3798645	393.516245	1.90E-04	177775	1902	signal sequence receptor subunit 4	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005784-&&-Sec61 translocon complex-%%-GO:0070062-&&-extracellular exosome	G:9606:SSR4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SSR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSR4	0.482696359	0.42019199	0.13299233	69	4	0.012604493	FALSE	10.25490196	SSR4	SSR4	189.5652174	10.6719878	0	69	0	0.77002258	FALSE	0	SSR4	362464	Infinity	0.04868403
788391	taxon:9606	2.36678746	303.816463	2.90E-04	177748	1902	signal transducer and activator of transcription 5B	gene	biological_process-&-1&-GO:0006573-&&-valine metabolic process-%%-GO:0048541-&&-Peyer's patch development-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0007595-&&-lactation-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0070672-&&-response to interleukin-15-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0007565-&&-female pregnancy-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0038161-&&-prolactin signaling pathway-%%-GO:0070670-&&-response to interleukin-4-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0042448-&&-progesterone metabolic process-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0019915-&&-lipid storage-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0046544-&&-development of secondary male sexual characteristics-%%-GO:0032819-&&-positive regulation of natural killer cell proliferation-%%-GO:0046543-&&-development of secondary female sexual characteristics-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006101-&&-citrate metabolic process-%%-GO:0006549-&&-isoleucine metabolic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0001553-&&-luteinization-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0030856-&&-regulation of epithelial cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032825-&&-positive regulation of natural killer cell differentiation-%%-GO:0000255-&&-allantoin metabolic process-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0045588-&&-positive regulation of gamma-delta T cell differentiation-%%-GO:0097531-&&-mast cell migration-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019218-&&-regulation of steroid metabolic process-%%-GO:0070669-&&-response to interleukin-2|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:STAT5B			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis	STAT5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT5B	0.477238917	0.42251365	0.15513342	69	4	0.005872086	FALSE	12.38461538	STAT5B	STAT5B	144.119403	12.75744285	0	68	0	0.77220209	FALSE	1	STAT5B	384452	Infinity	0.03632581
788401	taxon:9606	2.52544509	301.9986389	2.61E-04	177738	1902	serine/threonine kinase 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0046621-&&-negative regulation of organ growth-%%-GO:0007417-&&-central nervous system development-%%-GO:0060215-&&-primitive hemopoiesis-%%-GO:0001841-&&-neural tube formation-%%-GO:0003157-&&-endocardium development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060800-&&-regulation of cell differentiation involved in embryonic placenta development-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060706-&&-cell differentiation involved in embryonic placenta development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0004672-&&-protein kinase activity	G:9606:STK3			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	STK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK3	0.45272368	0.3959698	0.07779285	69	4	0.004303311	FALSE	7.526315789	STK3	STK3	96.73134328	7.772972973	0	68	0	0.74575915	FALSE	1	STK3	293788	Infinity	0.03235497
788497	taxon:9606	2.48873484	367.4930496	9.92E-05	177550	1902	small nuclear ribonucleoprotein polypeptide C	gene	biological_process-&-1&-GO:0000395-&&-mRNA 5'-splice site recognition-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0000243-&&-commitment complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071010-&&-prespliceosome-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0030619-&&-U1 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0030627-&&-pre-mRNA 5'-splice site binding-%%-GO:1990446-&&-U1 snRNP binding	G:9606:SNRPC			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPC	0.473995272	0.40181058	0.2039801	69	4	0.015475512	FALSE	17.50909091	SNRPC	SNRPC	202.8358209	18.11676656	0	68	0	0.75187753	FALSE	1	SNRPC	228644	Infinity	0.06290971
788830	taxon:9606	2.3763983	489.077385	1.85E-04	176798	1902	upstream binding transcription factor, RNA polymerase I	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006360-&&-transcription from RNA polymerase I promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:1902659-&&-regulation of glucose mediated signaling pathway|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0001165-&&-RNA polymerase I upstream control element sequence-specific DNA binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:UBTF				UBTF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBTF	0.492326581	0.42080488	0.12890095	69	4	0.012580523	FALSE	11.74	UBTF	UBTF	201.7014925	12.10703117	0	68	0	0.77060028	FALSE	1	UBTF	319726	Infinity	0.05126921
789071	taxon:9606	2.7444462	98.72434312	2.20E-04	159860	1902	keratin associated protein 10-8	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KRTAP10-8				KRTAP10-8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-8	0.386133847	0.36437224	0.15649028	69	4	0.001650747	FALSE	10.04545455	KRTAP10-8	KRTAP10-8	49.3880597	10.52380952	0	68	0	0.70925897	FALSE	1	KRTAP10-8	357642	Infinity	0.03015162
789266	taxon:9606	2.41342366	228.3482364	2.77E-04	175875	1902	beclin 1	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0045324-&&-late endosome to vacuole transport-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:1902425-&&-positive regulation of attachment of mitotic spindle microtubules to kinetochore-%%-GO:0032258-&&-CVT pathway-%%-GO:0006914-&&-autophagy-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:2000786-&&-positive regulation of autophagosome assembly-%%-GO:0006968-&&-cellular defense response-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0000910-&&-cytokinesis-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0042493-&&-response to drug-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0048666-&&-neuron development-%%-GO:0071275-&&-cellular response to aluminum ion-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0044804-&&-nucleophagy-%%-GO:0001666-&&-response to hypoxia-%%-GO:0033197-&&-response to vitamin E-%%-GO:0043652-&&-engulfment of apoptotic cell-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0007568-&&-aging-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:1905672-&&-negative regulation of lysosome organization-%%-GO:0010040-&&-response to iron(II) ion-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000422-&&-mitophagy-%%-GO:0051607-&&-defense response to virus-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0007040-&&-lysosome organization|cellular_component-&-1&-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0034271-&&-phosphatidylinositol 3-kinase complex, class III, type I-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005768-&&-endosome-%%-GO:0035032-&&-phosphatidylinositol 3-kinase complex, class III-%%-GO:0030425-&&-dendrite-%%-GO:0034272-&&-phosphatidylinositol 3-kinase complex, class III, type II-%%-GO:0010008-&&-endosome membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:BECN1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	BECN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BECN1	0.481681682	0.41434913	0.07010403	69	4	0.007443194	FALSE	7.894736842	BECN1	BECN1	137.8208955	8.154054054	0	68	0	0.76442939	FALSE	1	BECN1	360178	Infinity	0.03734784
789337	taxon:9606	2.50669608	345.9736857	1.05E-04	175710	1902	receptor interacting serine/threonine kinase 2	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070671-&&-response to interleukin-12-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0070673-&&-response to interleukin-18-%%-GO:0071223-&&-cellular response to lipoteichoic acid-%%-GO:0042098-&&-T cell proliferation-%%-GO:0034134-&&-toll-like receptor 2 signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0002250-&&-adaptive immune response-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0033091-&&-positive regulation of immature T cell proliferation-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0007254-&&-JNK cascade-%%-GO:0071225-&&-cellular response to muramyl dipeptide-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0001961-&&-positive regulation of cytokine-mediated signaling pathway-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0071224-&&-cellular response to peptidoglycan-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:0070427-&&-nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006954-&&-inflammatory response-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0045627-&&-positive regulation of T-helper 1 cell differentiation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0030274-&&-LIM domain binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0050700-&&-CARD domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004871-&&-signal transducer activity	G:9606:RIPK2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05131-&&-Shigellosis	RIPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK2	0.473715298	0.39893149	0.14608774	69	4	0.008811814	FALSE	12.58490566	RIPK2	RIPK2	132.4179105	13.02489589	0	68	0	0.74888399	FALSE	1	RIPK2	179326	Infinity	0.04292255
789473	taxon:9606	2.41547188	245.4650308	2.19E-04	175390	1902	peroxiredoxin 6	gene	biological_process-&-1&-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0016042-&&-lipid catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051920-&&-peroxiredoxin activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PRDX6			KEGG-&-1&-hsa01100-&&-Metabolic pathways	PRDX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX6	0.481103779	0.41399778	0.09859792	69	4	0.011064094	FALSE	9.357142857	PRDX6	PRDX6	172.3731343	9.615366092	0	68	0	0.76408802	FALSE	1	PRDX6	346388	Infinity	0.0469909
789539	taxon:9606	2.42051363	366.5211595	1.03E-04	175234	1902	squamous cell carcinoma antigen recognized by T-cells 3	gene	biological_process-&-1&-GO:0048872-&&-homeostasis of number of cells-%%-GO:0071425-&&-hematopoietic stem cell proliferation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0000902-&&-cell morphogenesis-%%-GO:1903586-&&-positive regulation of histone deubiquitination|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005691-&&-U6atac snRNP-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071002-&&-U4atac/U6atac snRNP-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0071001-&&-U4/U6 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex|molecular_function-&-1&-GO:0030621-&&-U4 snRNA binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0017070-&&-U6 snRNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030624-&&-U6atac snRNA binding	G:9606:SART3				SART3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SART3	0.490220049	0.41313546	0.12211669	69	4	0.012724424	FALSE	11.40384615	SART3	SART3	186.9701493	11.71888756	0	68	0	0.76324773	FALSE	1	SART3	209668	Infinity	0.05125865
789857	taxon:9606	2.36206082	1037.791732	6.50E-04	174500	1902	cytoskeleton associated protein 4	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005856-&&-cytoskeleton-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0042599-&&-lamellar body-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:CKAP4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	CKAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKAP4	0.488577521	0.42335912	0.07327001	69	4	0.01431892	FALSE	8.607843137	CKAP4	CKAP4	232.7313433	9.225978558	0	68	0	0.77298986	FALSE	1	CKAP4	925256	Infinity	0.05822877
789881	taxon:9606	2.4825902	454.4681607	2.75E-04	174440	1902	TNFAIP3 interacting protein 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0006954-&&-inflammatory response-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006412-&&-translation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0085032-&&-modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006952-&&-defense response-%%-GO:0009101-&&-glycoprotein biosynthetic process-%%-GO:0045071-&&-negative regulation of viral genome replication|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TNIP1				TNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNIP1	0.46627907	0.4028051	0.07281773	69	4	0.005509967	FALSE	8.073170732	TNIP1	TNIP1	113.0746269	8.354697264	0	68	0	0.75290163	FALSE	1	TNIP1	318214	Infinity	0.03478601
790014	taxon:9606	2.32818654	545.5237923	3.40E-04	174096	1902	tubulin gamma complex associated protein 2	gene	biological_process-&-1&-GO:0007020-&&-microtubule nucleation-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051298-&&-centrosome duplication|cellular_component-&-1&-GO:0008275-&&-gamma-tubulin small complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005816-&&-spindle pole body-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0016020-&&-membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:TUBGCP2				TUBGCP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBGCP2	0.494451295	0.42951885	0.14748508	69	4	0.012856616	FALSE	11.79245283	TUBGCP2	TUBGCP2	195.826087	12.18295839	0	69	0	0.77863558	FALSE	0	TUBGCP2	494536	Infinity	0.04656366
790038	taxon:9606	2.52355444	229.0591573	1.29E-04	174037	1902	topoisomerase (DNA) II binding protein 1	gene	biological_process-&-1&-GO:0033314-&&-mitotic DNA replication checkpoint-%%-GO:0006281-&&-DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005694-&&-chromosome-%%-GO:0016604-&&-nuclear body-%%-GO:0016605-&&-PML body-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:TOPBP1			KEGG-&-1&-hsa03440-&&-Homologous recombination	TOPBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOPBP1	0.471071953	0.39626647	0.10085934	69	4	0.011688086	FALSE	9.716981132	TOPBP1	TOPBP1	162.5074627	10.07898532	0	68	0	0.74607426	FALSE	1	TOPBP1	227606	Infinity	0.0538233
790158	taxon:9606	2.56010714	270.7783476	1.24E-04	173743	1902	centrosomal protein 152	gene	biological_process-&-1&-GO:0051298-&&-centrosome duplication-%%-GO:0098535-&&-de novo centriole assembly involved in multi-ciliated epithelial cell differentiation-%%-GO:0007099-&&-centriole replication-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0098536-&&-deuterosome-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CEP152				CEP152	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP152	0.451322454	0.39060865	0.10144928	69	4	0.004418238	FALSE	7.057142857	CEP152	CEP152	88.66666667	7.267379679	0	69	0	0.73998214	FALSE	0	CEP152	179196	Infinity	0.03196669
790176	taxon:9606	2.41421144	534.227696	1.19E-04	173708	1902	exportin 7	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005643-&&-nuclear pore-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005049-&&-nuclear export signal receptor activity	G:9606:XPO7				XPO7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO7	0.482696359	0.41421393	0.17647059	69	4	0.011387384	FALSE	11.58823529	XPO7	XPO7	177.6376812	12.03031915	0	69	0	0.76429809	FALSE	0	XPO7	262496	Infinity	0.04822127
790348	taxon:9606	2.50701119	751.4428469	1.06E-04	173262	1902	inhibitor of Bruton tyrosine kinase	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030292-&&-protein tyrosine kinase inhibitor activity-%%-GO:0019901-&&-protein kinase binding	G:9606:IBTK				IBTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IBTK	0.469555035	0.39888135	0.0877431	69	4	0.009770762	FALSE	8.352941176	IBTK	IBTK	136.6865672	8.829667679	0	68	0	0.74883147	FALSE	1	IBTK	204026	Infinity	0.04396908
790349	taxon:9606	2.38632425	492.7785375	4.81E-04	173257	1902	golgi reassembly stacking protein 2	gene	biological_process-&-1&-GO:0006996-&&-organelle organization-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GORASP2				GORASP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GORASP2	0.47894894	0.41905454	0.0400682	69	4	0.005561988	FALSE	3.918918919	GORASP2	GORASP2	121.1014493	4.055029461	0	69	0	0.76894596	FALSE	0	GORASP2	487386	Infinity	0.03151173
790467	taxon:9606	2.34016071	227.777147	0.00109526	172778	1902	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1	gene	biological_process-&-1&-GO:0046324-&&-regulation of glucose import-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0090003-&&-regulation of establishment of protein localization to plasma membrane-%%-GO:0007165-&&-signal transduction-%%-GO:0007049-&&-cell cycle-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005769-&&-early endosome-%%-GO:0016581-&&-NuRD complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0043422-&&-protein kinase B binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:APPL1	APPL1	TRUE	KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04211-&&-Longevity regulating pathway	APPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APPL1	0.483423749	0.42732108	0.06965174	69	4	0.007683119	FALSE	9.542857143	APPL1	APPL1	155.5522388	9.835294118	0	68	0	0.77663988	FALSE	1	APPL1	1055704	Infinity	0.03754427
790522	taxon:9606	2.5487632	317.361832	2.44E-04	172613	1902	tubulin gamma complex associated protein 4	gene	biological_process-&-1&-GO:0006461-&&-protein complex assembly-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0051298-&&-centrosome duplication-%%-GO:0031122-&&-cytoplasmic microtubule organization|cellular_component-&-1&-GO:0005816-&&-spindle pole body-%%-GO:0005813-&&-centrosome-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0016020-&&-membrane-%%-GO:0008274-&&-gamma-tubulin ring complex-%%-GO:0005874-&&-microtubule-%%-GO:0055037-&&-recycling endosome-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:TUBGCP4				TUBGCP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBGCP4	0.458810069	0.39234716	0.14398595	68	4	0.012214078	FALSE	12.12244898	TUBGCP4	TUBGCP4	138.1323529	12.41893939	0	68	0	0.7418728	FALSE	0	TUBGCP4	406642	Infinity	0.04875642
790737	taxon:9606	2.51063495	146.8167862	7.62E-05	171354	1902	ribosomal protein L26 like 1	gene	biological_process-&-1&-GO:0006412-&&-translation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0015934-&&-large ribosomal subunit|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL26L1			KEGG-&-1&-hsa03010-&&-Ribosome	RPL26L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL26L1	0.475541061	0.39830562	0.50834065	68	4	0.022991756	FALSE	36.79365079	RPL26L1	RPL26L1	207.7058824	37.61843501	0	68	0	0.74822751	FALSE	0	RPL26L1	130630	Infinity	0.06716098
790890	taxon:9606	2.35512841	195.7874147	1.05E-04	170757	1902	RNA 2',3'-cyclic phosphate and 5'-OH ligase	gene	biological_process-&-1&-GO:0001890-&&-placenta development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation|cellular_component-&-1&-GO:0072669-&&-tRNA-splicing ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0003972-&&-RNA ligase (ATP) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RTCB				RTCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RTCB	0.495520544	0.4246053	0.2594381	68	4	0.019853776	FALSE	18.67857143	RTCB	RTCB	271.5882353	19.16303633	0	68	0	0.77414527	FALSE	0	RTCB	222240	Infinity	0.06717493
791102	taxon:9606	2.45360013	267.8288514	7.34E-05	170050	1902	BRX1, biogenesis of ribosomes	gene	biological_process-&-1&-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:BRIX1				BRIX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRIX1	0.481681682	0.40756437	0.29631255	68	4	0.017835192	FALSE	22.01886792	BRIX1	BRIX1	207.1176471	22.49494175	0	68	0	0.75773331	FALSE	0	BRIX1	162544	Infinity	0.06000818
787244	taxon:9606	2.39751063	451.7043961	2.06E-04	179810	1902	interferon regulatory factor 3	gene	biological_process-&-1&-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0071359-&&-cellular response to dsRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0071888-&&-macrophage apoptotic process-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0039530-&&-MDA-5 signaling pathway-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0045351-&&-type I interferon biosynthetic process-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:IRF3	IRF3	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05133-&&-Pertussis	IRF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF3	0.484007242	0.4170993	0.1011655	68	4	0.007422406	FALSE	9.088888889	IRF3	IRF3	144.2878788	9.406529433	0	67	0	0.76708156	FALSE	1	IRF3	300898	Infinity	0.0381432
791454	taxon:9606	2.32991965	367.8788961	9.51E-05	168578	1902	AHNAK nucleoprotein	gene	biological_process-&-1&-GO:1901385-&&-regulation of voltage-gated calcium channel activity-%%-GO:0051259-&&-protein oligomerization-%%-GO:0043484-&&-regulation of RNA splicing|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0043034-&&-costamere-%%-GO:0005634-&&-nucleus-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion-%%-GO:0030315-&&-T-tubule-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0097493-&&-structural molecule activity conferring elasticity	G:9606:AHNAK				AHNAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHNAK	0.496902107	0.42919935	0.1967366	68	4	0.015624778	FALSE	16.10526316	AHNAK	AHNAK	234.3030303	16.58219026	0	67	0	0.77834673	FALSE	1	AHNAK	229740	Infinity	0.05568641
787347	taxon:9606	2.3450449	271.1333873	1.07E-04	179612	1902	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	gene	biological_process-&-1&-GO:0009257-&&-10-formyltetrahydrofolate biosynthetic process-%%-GO:0009086-&&-methionine biosynthetic process-%%-GO:0048702-&&-embryonic neurocranium morphogenesis-%%-GO:0019346-&&-transsulfuration-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007507-&&-heart development-%%-GO:0006164-&&-purine nucleotide biosynthetic process-%%-GO:0001780-&&-neutrophil homeostasis-%%-GO:0009113-&&-purine nucleobase biosynthetic process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0048703-&&-embryonic viscerocranium morphogenesis-%%-GO:0061053-&&-somite development-%%-GO:0009069-&&-serine family amino acid metabolic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0006555-&&-methionine metabolic process-%%-GO:0000105-&&-histidine biosynthetic process-%%-GO:0009070-&&-serine family amino acid biosynthetic process-%%-GO:0046655-&&-folic acid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004477-&&-methenyltetrahydrofolate cyclohydrolase activity-%%-GO:0004329-&&-formate-tetrahydrofolate ligase activity-%%-GO:0004488-&&-methylenetetrahydrofolate dehydrogenase (NADP+) activity-%%-GO:0004486-&&-methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity-%%-GO:0004487-&&-methylenetetrahydrofolate dehydrogenase (NAD+) activity-%%-GO:0005524-&&-ATP binding	G:9606:MTHFD1			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways	MTHFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTHFD1	0.493538462	0.42643107	0.15244755	68	4	0.016512748	FALSE	12.90566038	MTHFD1	MTHFD1	243.0757576	13.2581279	0	67	0	0.77582585	FALSE	1	MTHFD1	260998	Infinity	0.05904894
791503	taxon:9606	2.47360958	289.7274416	1.32E-04	168356	1902	ring finger and WD repeat domain 2	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010212-&&-response to ionizing radiation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:RFWD2			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	RFWD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFWD2	0.47667162	0.40426752	0.17995338	68	4	0.010603623	FALSE	14.625	RFWD2	RFWD2	158.5909091	15.26384256	0	67	0	0.7543984	FALSE	1	RFWD2	218778	Infinity	0.04777817
791855	taxon:9606	2.35276509	847.4643777	2.59E-04	182969	1902	acetyl-CoA carboxylase alpha	gene	biological_process-&-1&-GO:0001894-&&-tissue homeostasis-%%-GO:0006084-&&-acetyl-CoA metabolic process-%%-GO:0044268-&&-multicellular organismal protein metabolic process-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0006768-&&-biotin metabolic process-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:2001295-&&-malonyl-CoA biosynthetic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005739-&&-mitochondrion-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004075-&&-biotin carboxylase activity-%%-GO:0003989-&&-acetyl-CoA carboxylase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ACACA	ACACA	TRUE	KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa01212-&&-Fatty acid metabolism	ACACA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACACA	0.49066993	0.42503181	0.08516242	68	4	0.010505567	FALSE	7.06122449	ACACA	ACACA	190.1029412	7.454203899	0	68	0	0.77453915	FALSE	0	ACACA	429206	Infinity	0.0469179
792168	taxon:9606	2.54813298	442.4789873	3.84E-04	182491	1902	Fas ligand	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0046666-&&-retinal cell programmed cell death-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0070266-&&-necroptotic process-%%-GO:0070848-&&-response to growth factor-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0048388-&&-endosomal lumen acidification-%%-GO:1903514-&&-calcium ion transport from endoplasmic reticulum to cytosol-%%-GO:0070231-&&-T cell apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006955-&&-immune response-%%-GO:0030644-&&-cellular chloride ion homeostasis-%%-GO:0006915-&&-apoptotic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006925-&&-inflammatory cell apoptotic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005901-&&-caveola-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0060205-&&-cytoplasmic vesicle lumen-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0005123-&&-death receptor binding	G:9606:FASLG	FASLG	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05330-&&-Allograft rejection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	FASLG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FASLG	0.449425609	0.3924442	0.07550483	68	4	0.004253036	FALSE	6.555555556	FASLG	FASLG	101.6470588	6.770481243	0	68	0	0.74197784	FALSE	0	FASLG	584566	Infinity	0.03595698
792227	taxon:9606	2.36458169	520.8128787	2.29E-04	182380	1902	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2	gene	biological_process-&-1&-GO:0045822-&&-negative regulation of heart contraction-%%-GO:0033292-&&-T-tubule organization-%%-GO:0006984-&&-ER-nucleus signaling pathway-%%-GO:0032470-&&-positive regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1903515-&&-calcium ion transport from cytosol to endoplasmic reticulum-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:0006996-&&-organelle organization-%%-GO:0070296-&&-sarcoplasmic reticulum calcium ion transport-%%-GO:0007155-&&-cell adhesion-%%-GO:0014883-&&-transition between fast and slow fiber-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0086036-&&-regulation of cardiac muscle cell membrane potential-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0008544-&&-epidermis development-%%-GO:1990036-&&-calcium ion import into sarcoplasmic reticulum-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:1903233-&&-regulation of calcium ion-dependent exocytosis of neurotransmitter|cellular_component-&-1&-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0097470-&&-ribbon synapse-%%-GO:0031095-&&-platelet dense tubular network membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0031775-&&-lutropin-choriogonadotropic hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0086039-&&-calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential-%%-GO:0019899-&&-enzyme binding-%%-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0044548-&&-S100 protein binding	G:9606:ATP2A2			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP2A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP2A2	0.487982963	0.42290778	0.06899767	68	4	0.01026366	FALSE	6.428571429	ATP2A2	ATP2A2	195.6969697	6.739372698	0	67	0	0.77256972	FALSE	1	ATP2A2	500820	Infinity	0.04905626
788198	taxon:9606	2.4940917	255.7733645	1.31E-04	178098	1902	RB binding protein 5, histone lysine methyltransferase complex subunit	gene	biological_process-&-1&-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043627-&&-response to estrogen-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005730-&&-nucleolus-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:RBBP5			KEGG-&-1&-hsa04934-&&-Cushing syndrome	RBBP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP5	0.474696656	0.40094757	0.15337995	68	4	0.007958621	FALSE	10.47619048	RBBP5	RBBP5	135.5151515	10.80137128	0	67	0	0.75098472	FALSE	1	RBBP5	220576	Infinity	0.04227296
788510	taxon:9606	2.48936505	269.0860917	6.24E-05	177531	1902	SON DNA binding protein	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008380-&&-RNA splicing-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0006397-&&-mRNA processing-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0050733-&&-RS domain binding-%%-GO:0005515-&&-protein binding	G:9606:SON				SON	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SON	0.478520286	0.40170886	0.24539069	68	4	0.014786857	FALSE	18.31578947	SON	SON	185.4117647	18.76646825	0	68	0	0.75177249	FALSE	0	SON	151920	Infinity	0.05751857
792608	taxon:9606	2.47487002	449.9521329	1.93E-04	181730	1902	dishevelled segment polarity protein 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0021915-&&-neural tube development-%%-GO:0048675-&&-axon extension-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0099054-&&-presynapse assembly-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0050821-&&-protein stabilization-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0007411-&&-axon guidance-%%-GO:0001505-&&-regulation of neurotransmitter levels-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0035176-&&-social behavior-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0022007-&&-convergent extension involved in neural plate elongation-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048668-&&-collateral sprouting-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0060134-&&-prepulse inhibition-%%-GO:1905386-&&-positive regulation of protein localization to presynapse-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0007507-&&-heart development-%%-GO:0043113-&&-receptor clustering-%%-GO:0050808-&&-synapse organization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0043197-&&-dendritic spine-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0043005-&&-neuron projection-%%-GO:0045202-&&-synapse-%%-GO:0014069-&&-postsynaptic density-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030136-&&-clathrin-coated vesicle|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0003674-&&-molecular_function-%%-GO:0008013-&&-beta-catenin binding	G:9606:DVL1	DVL1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DVL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DVL1	0.468868752	0.40406162	0.09184149	68	4	0.005848815	FALSE	8.555555556	DVL1	DVL1	123.3181818	8.911556744	0	67	0	0.75418833	FALSE	1	DVL1	266988	Infinity	0.03734373
788545	taxon:9606	2.60658579	183.6314357	2.05E-04	177461	1902	serum response factor	gene	biological_process-&-1&-GO:0048821-&&-erythrocyte development-%%-GO:1900222-&&-negative regulation of beta-amyloid clearance-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0001947-&&-heart looping-%%-GO:0003257-&&-positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001666-&&-response to hypoxia-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030878-&&-thyroid gland development-%%-GO:0034097-&&-response to cytokine-%%-GO:0060055-&&-angiogenesis involved in wound healing-%%-GO:0009725-&&-response to hormone-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045214-&&-sarcomere organization-%%-GO:0051150-&&-regulation of smooth muscle cell differentiation-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0048589-&&-developmental growth-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0010735-&&-positive regulation of transcription via serum response element binding-%%-GO:0033561-&&-regulation of water loss via skin-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0048538-&&-thymus development-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0010669-&&-epithelial structure maintenance-%%-GO:0007507-&&-heart development-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0061145-&&-lung smooth muscle development-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0030220-&&-platelet formation-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0060425-&&-lung morphogenesis-%%-GO:0022028-&&-tangential migration from the subventricular zone to the olfactory bulb-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060532-&&-bronchus cartilage development-%%-GO:0002011-&&-morphogenesis of an epithelial sheet-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090398-&&-cellular senescence-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0045059-&&-positive thymic T cell selection-%%-GO:0031175-&&-neuron projection development-%%-GO:0060534-&&-trachea cartilage development-%%-GO:0060947-&&-cardiac vascular smooth muscle cell differentiation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0001764-&&-neuron migration-%%-GO:0021766-&&-hippocampus development-%%-GO:0001707-&&-mesoderm formation-%%-GO:0008306-&&-associative learning-%%-GO:0048666-&&-neuron development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030168-&&-platelet activation-%%-GO:0007616-&&-long-term memory-%%-GO:0090009-&&-primitive streak formation-%%-GO:0009636-&&-response to toxic substance-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0046016-&&-positive regulation of transcription by glucose-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0060218-&&-hematopoietic stem cell differentiation-%%-GO:0060324-&&-face development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0010736-&&-serum response element binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0070878-&&-primary miRNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SRF			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SRF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRF	0.432694902	0.38364362	0.0951049	68	4	0.004981083	FALSE	10.7027027	SRF	SRF	94.68181818	11.02688172	0	67	0	0.7322357	FALSE	1	SRF	230688	Infinity	0.03801885
788713	taxon:9606	2.35402552	401.4571326	1.34E-04	177133	1902	tropomyosin 4	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0006936-&&-muscle contraction-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane-%%-GO:0005862-&&-muscle thin filament tropomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0005509-&&-calcium ion binding	G:9606:TPM4			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM4	0.495367511	0.42480423	0.15320457	68	4	0.011489525	FALSE	11.88679245	TPM4	TPM4	184.4558824	12.39702698	0	68	0	0.77432908	FALSE	0	TPM4	270796	Infinity	0.04548884
788854	taxon:9606	2.35560107	349.2992841	1.90E-04	176750	1902	valyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006438-&&-valyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004832-&&-valine-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:VARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	VARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VARS	0.491572173	0.4245201	0.12028095	68	4	0.012945424	FALSE	10.42553191	VARS	VARS	210	10.79837421	0	68	0	0.77406649	FALSE	0	VARS	372148	Infinity	0.05200061
792972	taxon:9606	2.31636994	418.3388329	2.59E-04	181066	1902	FK506 binding protein 4	gene	biological_process-&-1&-GO:0046661-&&-male sex differentiation-%%-GO:0006457-&&-protein folding-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0006463-&&-steroid hormone receptor complex assembly-%%-GO:0031111-&&-negative regulation of microtubule polymerization or depolymerization-%%-GO:0031503-&&-protein complex localization-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006825-&&-copper ion transport-%%-GO:0007566-&&-embryo implantation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0030850-&&-prostate gland development-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0044295-&&-axonal growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0032767-&&-copper-dependent protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0005524-&&-ATP binding	G:9606:FKBP4			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	FKBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP4	0.491722869	0.43170997	0.11655012	68	4	0.010719026	FALSE	10.34782609	FKBP4	FKBP4	197.030303	10.76878594	0	67	0	0.78060501	FALSE	1	FKBP4	397956	Infinity	0.04573239
792970	taxon:9606	2.55538049	128.9925952	1.56E-04	181064	1902	forkhead box G1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0016199-&&-axon midline choice point recognition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007420-&&-brain development-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0048664-&&-neuron fate determination-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0021852-&&-pyramidal neuron migration-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXG1			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway	FOXG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXG1	0.448922474	0.39133115	0.04872695	68	4	0.005251693	FALSE	4.24137931	FOXG1	FOXG1	99.13235294	4.392857143	0	68	0	0.74076992	FALSE	0	FOXG1	234504	Infinity	0.03538455
792980	taxon:9606	2.3530802	448.6178849	1.58E-04	181048	1902	forkhead box O3	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0001547-&&-antral ovarian follicle growth-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0071386-&&-cellular response to corticosterone stimulus-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0001556-&&-oocyte maturation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071548-&&-response to dexamethasone-%%-GO:0031667-&&-response to nutrient levels-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1904646-&&-cellular response to beta-amyloid-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:1901300-&&-positive regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0001544-&&-initiation of primordial ovarian follicle growth-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:2000177-&&-regulation of neural precursor cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:1990785-&&-response to water-immersion restraint stress-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:FOXO3	FOXO3	TRUE	KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04137-&&-Mitophagy - animal	FOXO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXO3	0.488875343	0.42497489	0.16549605	68	4	0.010904714	FALSE	12.87272727	FOXO3	FOXO3	197.4264706	13.61213273	0	68	0	0.77448663	FALSE	0	FOXO3	289218	Infinity	0.0485674
793070	taxon:9606	2.50890184	293.8408776	1.27E-04	180811	1902	general transcription factor IIB	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:GTF2B			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis	GTF2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2B	0.469555035	0.39858076	0.13426573	68	4	0.007378725	FALSE	10.63414634	GTF2B	GTF2B	128.4848485	11.10525888	0	67	0	0.74851636	FALSE	1	GTF2B	200210	Infinity	0.04142847
793214	taxon:9606	2.31636994	434.1034434	1.70E-04	180516	1902	heat shock protein family A (Hsp70) member 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0007286-&&-spermatid development-%%-GO:0009409-&&-response to cold-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042026-&&-protein refolding-%%-GO:0007140-&&-male meiosis-%%-GO:0009408-&&-response to heat|cellular_component-&-1&-GO:0072687-&&-meiotic spindle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0036128-&&-CatSper complex-%%-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:HSPA2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa05164-&&-Influenza A-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA2	0.49598021	0.43170997	0.13915716	68	4	0.012258786	FALSE	10.47169811	HSPA2	HSPA2	195.3823529	10.84067414	0	68	0	0.78060501	FALSE	0	HSPA2	339730	Infinity	0.04552963
793217	taxon:9606	2.37293209	182.3519515	9.80E-05	180513	1902	heat shock protein family A (Hsp70) member 6	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0034605-&&-cellular response to heat-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042026-&&-protein refolding|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042623-&&-ATPase activity, coupled	G:9606:HSPA6			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa03040-&&-Spliceosome-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA6	0.491271057	0.42141956	0.14881475	68	4	0.012526427	FALSE	11.34	HSPA6	HSPA6	191.5441177	11.57837603	0	68	0	0.77117798	FALSE	0	HSPA6	246168	Infinity	0.04859546
789276	taxon:9606	2.46683473	438.3921024	3.38E-04	175840	1902	sorting nexin 3	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:2000642-&&-negative regulation of early endosome to late endosome transport-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0010324-&&-membrane invagination-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0009617-&&-response to bacterium-%%-GO:0022615-&&-protein to membrane docking-%%-GO:0051224-&&-negative regulation of protein transport-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0070676-&&-intralumenal vesicle formation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031901-&&-early endosome membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0032009-&&-early phagosome-%%-GO:0005829-&&-cytosol-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0010314-&&-phosphatidylinositol-5-phosphate binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding	G:9606:SNX3			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX3	0.473715298	0.40537779	0.07769974	68	4	0.006843398	FALSE	5.833333333	SNX3	SNX3	132.3235294	6.008825417	0	68	0	0.75552755	FALSE	0	SNX3	419932	Infinity	0.03953525
789367	taxon:9606	2.33905782	457.3200981	8.92E-05	175649	1902	BUB3, mitotic checkpoint protein	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0071173-&&-spindle assembly checkpoint-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051321-&&-meiotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BUB3			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	BUB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB3	0.497981993	0.42752257	0.19973661	68	4	0.018955059	FALSE	15.01639344	BUB3	BUB3	277.8235294	15.77002789	0	68	0	0.7768237	FALSE	0	BUB3	248758	Infinity	0.06694543
789972	taxon:9606	2.5720813	362.6052167	1.56E-04	174215	1902	GABA type A receptor-associated protein	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0061024-&&-membrane organization-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0016236-&&-macroautophagy-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0097225-&&-sperm midpiece-%%-GO:0005930-&&-axoneme-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005764-&&-lysosome-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005829-&&-cytosol-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0050811-&&-GABA receptor binding	G:9606:GABARAP			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04136-&&-Autophagy - other	GABARAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABARAP	0.453748232	0.3887902	0.10722611	68	4	0.004656606	FALSE	7.925	GABARAP	GABARAP	84.90909091	8.346131459	0	67	0	0.73798645	FALSE	1	GABARAP	198796	Infinity	0.03139049
790124	taxon:9606	2.43548133	211.8638478	6.49E-04	173820	1902	DEAD-box helicase 19B	gene	biological_process-&-1&-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:DDX19B				DDX19B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX19B	0.469555035	0.41059645	0.03467954	68	4	0.005248311	FALSE	3.655172414	DDX19B	DDX19B	105.0882353	3.785714286	0	68	0	0.76075311	FALSE	0	DDX19B	589764	Infinity	0.02979634
790233	taxon:9606	2.62218371	161.3374866	2.37E-04	173563	1902	microtubule associated scaffold protein 2	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008017-&&-microtubule binding	G:9606:MTUS2				MTUS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTUS2	0.438490979	0.38136153	0.02703963	68	4	0.00366978	FALSE	3.928571429	MTUS2	MTUS2	73.21212121	4.074074074	0	67	0	0.72963605	FALSE	1	MTUS2	321932	Infinity	0.0307513
790932	taxon:9606	2.46982827	315.4067474	5.17E-05	170674	1902	splicing factor 3b subunit 6	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0001825-&&-blastocyst formation|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0005686-&&-U2 snRNP-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SF3B6			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B6	0.478092399	0.40488645	0.27403846	67	4	0.015733475	FALSE	20.17741935	SF3B6	SF3B6	193.9846154	20.9395894	0	66	0	0.75502862	FALSE	1	SF3B6	125168	Infinity	0.05810942
791126	taxon:9606	2.41878053	312.0051175	3.63E-04	169952	1902	erbb2 interacting protein	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0071638-&&-negative regulation of monocyte chemotactic protein-1 production-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070433-&&-negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045175-&&-basal protein localization-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0006605-&&-protein targeting-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005604-&&-basement membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0030056-&&-hemidesmosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005176-&&-ErbB-2 class receptor binding	G:9606:ERBIN			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	ERBIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBIN	0.477096966	0.41343147	0.08317308	67	4	0.005948444	FALSE	8.974358974	ERBIN	ERBIN	131.1384615	9.345112782	0	66	0	0.76353658	FALSE	1	ERBIN	388148	Infinity	0.03587918
787205	taxon:9606	2.36269104	497.9444064	2.61E-04	179870	1902	microtubule associated protein 1B	gene	biological_process-&-1&-GO:0016358-&&-dendrite development-%%-GO:0047497-&&-mitochondrion transport along microtubule-%%-GO:0048675-&&-axon extension-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0032387-&&-negative regulation of intracellular transport-%%-GO:0061162-&&-establishment of monopolar cell polarity-%%-GO:0009987-&&-cellular process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005829-&&-cytosol-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:MAP1B				MAP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1B	0.491722869	0.4232462	0.09497965	67	4	0.012725652	FALSE	7.72	MAP1B	MAP1B	199.9253731	8.126507436	0	67	0	0.77288483	FALSE	0	MAP1B	418078	Infinity	0.05001401
791696	taxon:9606	2.55317473	196.1852558	1.46E-04	167391	1902	SET domain containing lysine methyltransferase 7	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045471-&&-response to ethanol-%%-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:0051570-&&-regulation of histone H3-K9 methylation-%%-GO:0018027-&&-peptidyl-lysine dimethylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070828-&&-heterochromatin organization-%%-GO:0006325-&&-chromatin organization-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity	G:9606:SETD7			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa00310-&&-Lysine degradation	SETD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETD7	0.451703745	0.39166924	0.22259615	67	4	0.014498033	FALSE	17.66666667	SETD7	SETD7	202.5538462	18.11241847	0	66	0	0.74113755	FALSE	1	SETD7	276488	Infinity	0.07153574
787800	taxon:9606	2.6451867	642.3764625	2.67E-04	178770	1902	protein kinase AMP-activated non-catalytic subunit beta 2	gene	biological_process-&-1&-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:PRKAB2			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04921-&&-Oxytocin signaling pathway	PRKAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAB2	0.428075794	0.37804515	0.05192308	67	4	0.002957723	FALSE	5.432432432	PRKAB2	PRKAB2	69.16923077	6.208809551	0	66	0	0.72580222	FALSE	1	PRKAB2	279448	Infinity	0.03093488
787794	taxon:9606	2.53348038	509.2665585	3.28E-04	178772	1902	protein kinase AMP-activated catalytic subunit alpha 2	gene	biological_process-&-1&-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0014850-&&-response to muscle activity-%%-GO:0016236-&&-macroautophagy-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0006950-&&-response to stress-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0048511-&&-rhythmic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0050405-&&-[acetyl-CoA carboxylase] kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0047322-&&-[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	G:9606:PRKAA2	PRKAA2	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	PRKAA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAA2	0.452213138	0.39471393	0.04794211	67	4	0.00386391	FALSE	4.028571429	PRKAA2	PRKAA2	87.65671642	4.203575869	0	67	0	0.74441994	FALSE	0	PRKAA2	357122	Infinity	0.02970382
787885	taxon:9606	2.49566724	161.0517887	3.72E-05	178659	1902	proteasome subunit beta 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0045296-&&-cadherin binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB6			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB6	0.478092399	0.40069444	0.47263682	67	4	0.011194344	FALSE	32.34482759	PSMB6	PSMB6	169.0746269	33.46748571	0	67	0	0.75072213	FALSE	0	PSMB6	110328	Infinity	0.05316812
792207	taxon:9606	2.412951	307.6543713	1.45E-04	182419	1902	asparagine synthetase (glutamine-hydrolyzing)	gene	biological_process-&-1&-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0009416-&&-response to light stimulus-%%-GO:0032354-&&-response to follicle-stimulating hormone-%%-GO:0070981-&&-L-asparagine biosynthetic process-%%-GO:0043200-&&-response to amino acid-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006529-&&-asparagine biosynthetic process-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0001889-&&-liver development-%%-GO:0031427-&&-response to methotrexate-%%-GO:0042149-&&-cellular response to glucose starvation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004066-&&-asparagine synthase (glutamine-hydrolyzing) activity-%%-GO:0005515-&&-protein binding-%%-GO:0048037-&&-cofactor binding	G:9606:ASNS			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	ASNS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASNS	0.477523072	0.4144303	0.12483039	67	4	0.008994053	FALSE	7.357142857	ASNS	ASNS	157.5223881	7.55657706	0	67	0	0.76450817	FALSE	0	ASNS	245606	Infinity	0.04266587
788271	taxon:9606	2.38112494	406.6005176	1.41E-04	177965	1902	ribosomal protein S6 kinase B1	gene	biological_process-&-1&-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0007616-&&-long-term memory-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0007281-&&-germ cell development-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0048633-&&-positive regulation of skeletal muscle tissue growth-%%-GO:0032868-&&-response to insulin-%%-GO:0046324-&&-regulation of glucose import-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0045471-&&-response to ethanol-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0007584-&&-response to nutrient-%%-GO:0009749-&&-response to glucose-%%-GO:0043201-&&-response to leucine-%%-GO:0042493-&&-response to drug-%%-GO:0031929-&&-TOR signaling-%%-GO:0016477-&&-cell migration-%%-GO:0009408-&&-response to heat-%%-GO:0009611-&&-response to wounding-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0033574-&&-response to testosterone-%%-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0033762-&&-response to glucagon-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0007568-&&-aging-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001662-&&-behavioral fear response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0016301-&&-kinase activity-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004711-&&-ribosomal protein S6 kinase activity	G:9606:RPS6KB1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	RPS6KB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KB1	0.47794994	0.41996956	0.11586538	67	4	0.00758773	FALSE	10.4	RPS6KB1	RPS6KB1	153.0923077	10.7817081	0	66	0	0.76981251	FALSE	1	RPS6KB1	258072	Infinity	0.03936151
792564	taxon:9606	2.43043958	318.9208942	1.40E-04	181810	1902	Cbl proto-oncogene B	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0006607-&&-NLS-bearing protein import into nucleus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:CBLB			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04144-&&-Endocytosis-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	CBLB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBLB	0.47134881	0.4114482	0.20240385	67	4	0.006595787	FALSE	16.82222222	CBLB	CBLB	154.7076923	17.54892526	0	66	0	0.7615934	FALSE	1	CBLB	233462	Infinity	0.04333118
792623	taxon:9606	2.42208918	603.0621471	1.92E-04	181703	1902	enoyl-CoA hydratase, short chain 1	gene	biological_process-&-1&-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0005515-&&-protein binding	G:9606:ECHS1			KEGG-&-1&-hsa00380-&&-Tryptophan metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	ECHS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECHS1	0.484445787	0.41286671	0.08173077	67	4	0.008173761	FALSE	8.26	ECHS1	ECHS1	152.8	8.865401524	0	66	0	0.76298514	FALSE	1	ECHS1	290696	Infinity	0.04209031
788582	taxon:9606	2.35118954	258.2390323	1.68E-04	177396	1902	threonyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006412-&&-translation-%%-GO:0006435-&&-threonyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0004829-&&-threonine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:TARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	TARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARS	0.493690366	0.42531663	0.13613749	67	4	0.014973741	FALSE	10.08333333	TARS	TARS	230.2238806	10.38641453	0	67	0	0.77480174	FALSE	0	TARS	305956	Infinity	0.05645144
788741	taxon:9606	2.55270206	117.2553659	2.53E-04	177058	1902	translin associated factor X	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0015031-&&-protein transport-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:TSNAX				TSNAX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSNAX	0.452468265	0.39174176	0.02451923	67	4	0.004593606	FALSE	4.259259259	TSNAX	TSNAX	87.12307692	4.423076923	0	66	0	0.74121632	FALSE	1	TSNAX	267078	Infinity	0.0310778
792858	taxon:9606	2.46699228	184.510336	5.14E-05	181263	1902	ERCC excision repair 6, chromatin remodeling factor	gene	biological_process-&-1&-GO:0045494-&&-photoreceptor cell maintenance-%%-GO:0006284-&&-base-excision repair-%%-GO:0007256-&&-activation of JNKK activity-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0009636-&&-response to toxic substance-%%-GO:0009411-&&-response to UV-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000303-&&-response to superoxide-%%-GO:0006290-&&-pyrimidine dimer repair-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0010224-&&-response to UV-B-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0010165-&&-response to X-ray-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding	G:9606:ERCC6			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair	ERCC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC6	0.482260974	0.4053519	0.28493894	67	4	0.018855922	FALSE	21.1754386	ERCC6	ERCC6	244.0149254	21.64941147	0	67	0	0.75550129	FALSE	0	ERCC6	155750	Infinity	0.07253714
792926	taxon:9606	2.44398929	174.2879906	1.42E-04	181132	1902	cyclin G associated kinase	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:1905224-&&-clathrin-coated pit assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0072318-&&-clathrin coat disassembly-%%-GO:0007049-&&-cell cycle-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0007030-&&-Golgi organization-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0090160-&&-Golgi to lysosome transport-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0072600-&&-establishment of protein localization to Golgi-%%-GO:0016191-&&-synaptic vesicle uncoating-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007029-&&-endoplasmic reticulum organization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0030332-&&-cyclin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:GAK				GAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAK	0.470519214	0.4091671	0.1275441	67	4	0.006014093	FALSE	8.314285714	GAK	GAK	120.119403	8.558823529	0	67	0	0.75933512	FALSE	0	GAK	216636	Infinity	0.03441948
792965	taxon:9606	2.53332283	282.2102282	2.89E-04	181078	1902	four and a half LIM domains 3	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007517-&&-muscle organ development|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0001725-&&-stress fiber-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:FHL3				FHL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FHL3	0.451449479	0.39473848	0.04855769	67	4	0.004192084	FALSE	7.0625	FHL3	FHL3	92.18461538	7.314217443	0	66	0	0.7444462	FALSE	1	FHL3	299996	Infinity	0.03151314
792978	taxon:9606	2.47691823	406.4100674	1.45E-04	181052	1902	forkhead box M1	gene	biological_process-&-1&-GO:0090344-&&-negative regulation of cell aging-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:2000781-&&-positive regulation of double-strand break repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0071156-&&-regulation of cell cycle arrest|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXM1			KEGG-&-1&-hsa04218-&&-Cellular senescence	FOXM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXM1	0.473156342	0.4037275	0.0737223	67	4	0.007514025	FALSE	5.6875	FOXM1	FOXM1	132.4328358	5.875902508	0	67	0	0.75384696	FALSE	0	FOXM1	234860	Infinity	0.04027352
788919	taxon:9606	2.53316527	319.3528197	2.56E-04	176596	1902	breast cancer anti-estrogen resistance 3	gene	biological_process-&-1&-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:BCAR3				BCAR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAR3	0.458023986	0.39476303	0.03075531	67	4	0.007092581	FALSE	3.073170732	BCAR3	BCAR3	101.2537313	3.15530303	0	67	0	0.74447245	FALSE	0	BCAR3	309786	Infinity	0.03462461
793289	taxon:9606	2.25476603	386.5163733	5.52E-04	180368	1902	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	gene	biological_process-&-1&-GO:0035965-&&-cardiolipin acyl-chain remodeling-%%-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005740-&&-mitochondrial envelope-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016509-&&-long-chain-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0003988-&&-acetyl-CoA C-acyltransferase activity-%%-GO:0003723-&&-RNA binding	G:9606:HADHB			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	HADHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HADHB	0.498136646	0.443505	0.11080959	67	4	0.012894084	FALSE	9.46	HADHB	HADHB	229.8059702	9.749632836	0	67	0	0.79087233	FALSE	0	HADHB	643158	Infinity	0.04914452
789254	taxon:9606	2.37482275	477.7518452	7.19E-05	175888	1902	eukaryotic translation initiation factor 3 subunit D	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0002191-&&-cap-dependent translational initiation-%%-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0006413-&&-translational initiation-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0001732-&&-formation of cytoplasmic translation initiation complex|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0098808-&&-mRNA cap binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3D			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3D	0.494298921	0.42108406	0.21483492	67	4	0.016026618	FALSE	14.21666667	EIF3D	EIF3D	220.2089552	14.95201122	0	67	0	0.77086287	FALSE	0	EIF3D	195508	Infinity	0.05621116
789430	taxon:9606	2.38427604	732.5416037	1.64E-04	175497	1902	cytoskeleton associated protein 5	gene	biological_process-&-1&-GO:0046785-&&-microtubule polymerization-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0030951-&&-establishment or maintenance of microtubule cytoskeleton polarity-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0050658-&&-RNA transport-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007051-&&-spindle organization-%%-GO:0051298-&&-centrosome duplication|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0000776-&&-kinetochore-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0000922-&&-spindle pole|molecular_function-&-1&-GO:0051010-&&-microtubule plus-end binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CKAP5				CKAP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKAP5	0.487537994	0.41941452	0.07259615	67	4	0.011183474	FALSE	7.365384615	CKAP5	CKAP5	198.5076923	7.683950331	0	66	0	0.76928733	FALSE	1	CKAP5	323844	Infinity	0.05146026
789607	taxon:9606	2.36930833	766.0401905	3.25E-04	175067	1902	major vault protein	gene	biological_process-&-1&-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0051028-&&-mRNA transport-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0015031-&&-protein transport-%%-GO:0023057-&&-negative regulation of signaling-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MVP				MVP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MVP	0.490070272	0.4220641	0.06971154	67	4	0.008469352	FALSE	7.782608696	MVP	MVP	156.1076923	8.331118339	0	66	0	0.77178194	FALSE	1	MVP	453402	Infinity	0.03941166
789712	taxon:9606	2.33858516	404.6467448	1.49E-04	174847	1902	dynactin subunit 2	gene	biological_process-&-1&-GO:0032402-&&-melanosome transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0008283-&&-cell proliferation-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005869-&&-dynactin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000776-&&-kinetochore-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030286-&&-dynein complex-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030507-&&-spectrin binding	G:9606:DCTN2			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05016-&&-Huntington disease	DCTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCTN2	0.49247774	0.42760897	0.13894231	67	4	0.010099332	FALSE	12.08	DCTN2	DCTN2	187.0923077	12.39048177	0	66	0	0.77690247	FALSE	1	DCTN2	264114	Infinity	0.0449488
789820	taxon:9606	2.37104144	309.2709991	1.64E-04	174570	1902	PPARG coactivator 1 alpha	gene	biological_process-&-1&-GO:0008209-&&-androgen metabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1904635-&&-positive regulation of glomerular visceral epithelial cell apoptotic process-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0071250-&&-cellular response to nitrite-%%-GO:2000272-&&-negative regulation of receptor activity-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060612-&&-adipose tissue development-%%-GO:1901558-&&-response to metformin-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1904639-&&-cellular response to resveratrol-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0007623-&&-circadian rhythm-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006397-&&-mRNA processing-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0045333-&&-cellular respiration-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:1901863-&&-positive regulation of muscle tissue development-%%-GO:0002931-&&-response to ischemia-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0046321-&&-positive regulation of fatty acid oxidation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:1901860-&&-positive regulation of mitochondrial DNA metabolic process-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0042594-&&-response to starvation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0000422-&&-mitophagy-%%-GO:0071871-&&-response to epinephrine-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:2000184-&&-positive regulation of progesterone biosynthetic process-%%-GO:0006012-&&-galactose metabolic process-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0090258-&&-negative regulation of mitochondrial fission-%%-GO:0071313-&&-cellular response to caffeine-%%-GO:0043201-&&-response to leucine-%%-GO:0045722-&&-positive regulation of gluconeogenesis-%%-GO:0009409-&&-response to cold-%%-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0051552-&&-flavone metabolic process-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0002021-&&-response to dietary excess-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0071332-&&-cellular response to fructose stimulus-%%-GO:1901857-&&-positive regulation of cellular respiration-%%-GO:0021549-&&-cerebellum development-%%-GO:0050821-&&-protein stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:2000507-&&-positive regulation of energy homeostasis-%%-GO:0030900-&&-forebrain development-%%-GO:0006461-&&-protein complex assembly-%%-GO:0071873-&&-response to norepinephrine-%%-GO:0042493-&&-response to drug-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1904637-&&-cellular response to ionomycin-%%-GO:0014850-&&-response to muscle activity-%%-GO:1904640-&&-response to methionine-%%-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0035865-&&-cellular response to potassium ion-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0007568-&&-aging-%%-GO:0007586-&&-digestion-%%-GO:1990845-&&-adaptive thermogenesis-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0097440-&&-apical dendrite-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:1990843-&&-subsarcolemmal mitochondrion-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0016605-&&-PML body-%%-GO:1990844-&&-interfibrillar mitochondrion|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0050681-&&-androgen receptor binding	G:9606:PPARGC1A	PPARGC1A	TRUE	KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05016-&&-Huntington disease-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	PPARGC1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARGC1A	0.486650485	0.4217556	0.15829941	67	4	0.009045517	FALSE	11.74468085	PPARGC1A	PPARGC1A	167.1791045	12.23160659	0	67	0	0.77149309	FALSE	0	PPARGC1A	284144	Infinity	0.04226277
789807	taxon:9606	2.40712147	451.1468735	1.50E-04	174612	1902	ubiquitination factor E4B	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0008626-&&-granzyme-mediated apoptotic signaling pathway-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0031175-&&-neuron projection development-%%-GO:0009411-&&-response to UV-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0051117-&&-ATPase binding	G:9606:UBE4B			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE4B	0.483569491	0.41543396	0.13221154	67	4	0.006657062	FALSE	10.02272727	UBE4B	UBE4B	144.8923077	10.43665803	0	66	0	0.76547975	FALSE	1	UBE4B	258284	Infinity	0.03890989
789887	taxon:9606	2.3962502	467.4626266	1.58E-04	174424	1902	structural maintenance of chromosomes 2	gene	biological_process-&-1&-GO:0051383-&&-kinetochore organization-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0045132-&&-meiotic chromosome segregation-%%-GO:0010032-&&-meiotic chromosome condensation-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0000796-&&-condensin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:SMC2				SMC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC2	0.484153335	0.41731869	0.11080959	67	4	0.009483156	FALSE	6.066666667	SMC2	SMC2	173.7313433	6.235019102	0	67	0	0.76729163	FALSE	0	SMC2	321038	Infinity	0.04571509
789910	taxon:9606	2.31195841	324.40914	7.87E-05	174380	1902	insulin like growth factor 2 mRNA binding protein 1	gene	biological_process-&-1&-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0051028-&&-mRNA transport-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0010610-&&-regulation of mRNA stability involved in response to stress-%%-GO:0022013-&&-pallium cell proliferation in forebrain-%%-GO:0010467-&&-gene expression-%%-GO:0042035-&&-regulation of cytokine biosynthetic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030424-&&-axon-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045182-&&-translation regulator activity	G:9606:IGF2BP1			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	IGF2BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2BP1	0.496902107	0.43253373	0.16372682	67	4	0.019969324	FALSE	11.5	IGF2BP1	IGF2BP1	277.2835821	11.9034951	0	67	0	0.78134027	FALSE	0	IGF2BP1	257044	Infinity	0.06422716
789943	taxon:9606	2.40270994	244.1028898	1.37E-04	174294	1902	nucleoporin 50	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:NUP50			KEGG-&-1&-hsa03013-&&-RNA transport	NUP50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP50	0.482406015	0.41619672	0.08955224	67	4	0.007854028	FALSE	6.743589744	NUP50	NUP50	145.9402985	6.949122807	0	67	0	0.76621501	FALSE	0	NUP50	235302	Infinity	0.03879168
790339	taxon:9606	2.61729951	28.21001684	2.08E-04	173290	1902	paroxysmal nonkinesigenic dyskinesia	gene	biological_process-&-1&-GO:0019243-&&-methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione-%%-GO:0050884-&&-neuromuscular process controlling posture-%%-GO:0046929-&&-negative regulation of neurotransmitter secretion-%%-GO:0032225-&&-regulation of synaptic transmission, dopaminergic-%%-GO:0042053-&&-regulation of dopamine metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004416-&&-hydroxyacylglutathione hydrolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PNKD				PNKD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNKD	0.395268605	0.3820732	0.01447309	67	4	0.001439862	FALSE	1.363636364	PNKD	PNKD	57.53731343	1.5	0	67	0	0.73045008	FALSE	0	PNKD	195720	Infinity	0.02390812
790367	taxon:9606	2.46037498	103.6318161	4.00E-04	173205	1902	mitogen-activated protein kinase 8 interacting protein 2	gene	biological_process-&-1&-GO:0007172-&&-signal complex assembly-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0046958-&&-nonassociative learning-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0007254-&&-JNK cascade-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0001662-&&-behavioral fear response-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0007617-&&-mating behavior-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0035176-&&-social behavior|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019894-&&-kinesin binding-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0032403-&&-protein complex binding	G:9606:MAPK8IP2			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAPK8IP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK8IP2	0.450815065	0.40644211	0.05	67	4	0.004174511	FALSE	5.782608696	MAPK8IP2	MAPK8IP2	101.1846154	6.045454545	0	66	0	0.75660417	FALSE	1	MAPK8IP2	378274	Infinity	0.02992493
790445	taxon:9606	2.48873484	206.6834046	3.45E-04	172842	1902	tuftelin interacting protein 11	gene	biological_process-&-1&-GO:0031214-&&-biomineral tissue development-%%-GO:0006396-&&-RNA processing-%%-GO:0031848-&&-protection from non-homologous end joining at telomere-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0000390-&&-spliceosomal complex disassembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1904876-&&-negative regulation of DNA ligase activity-%%-GO:2001033-&&-negative regulation of double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0071008-&&-U2-type post-mRNA release spliceosomal complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TFIP11				TFIP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFIP11	0.465332173	0.40181058	0.04703754	67	4	0.005354297	FALSE	4.269230769	TFIP11	TFIP11	111.1044776	4.44	0	67	0	0.75187753	FALSE	0	TFIP11	397106	Infinity	0.03443176
790820	taxon:9606	2.57050575	204.2977027	2.15E-04	171097	1902	intersectin 2	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0006897-&&-endocytosis-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:ITSN2				ITSN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITSN2	0.429221301	0.3890285	0.03621032	66	4	0.003370265	FALSE	5.185185185	ITSN2	ITSN2	83.3125	5.384615385	0	65	0	0.73824904	FALSE	1	ITSN2	228282	Infinity	0.03062799
790917	taxon:9606	2.40696392	417.8288165	1.18E-04	170700	1902	tripartite motif containing 33	gene	biological_process-&-1&-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070412-&&-R-SMAD binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:TRIM33				TRIM33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM33	0.488875343	0.41546115	0.14781746	66	4	0.011845157	FALSE	11.80769231	TRIM33	TRIM33	203.5625	12.34701443	0	65	0	0.76550601	FALSE	1	TRIM33	266554	Infinity	0.0544014
790997	taxon:9606	2.40570348	438.2020203	1.84E-04	170463	1902	centrosomal protein 55	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006997-&&-nucleus organization|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005886-&&-plasma membrane-%%-GO:0005814-&&-centriole-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP55				CEP55	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP55	0.48371532	0.41567883	0.1155754	66	4	0.007340239	FALSE	9.977777778	CEP55	CEP55	150.921875	10.2695584	0	65	0	0.76571609	FALSE	1	CEP55	278070	Infinity	0.04041901
791174	taxon:9606	2.33385852	970.5915654	1.40E-04	169826	1902	importin 9	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:IPO9				IPO9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO9	0.495214572	0.42847499	0.12307692	66	4	0.010227778	FALSE	8.375	IPO9	IPO9	192.969697	9.084988253	0	66	0	0.77769025	FALSE	0	IPO9	300008	Infinity	0.0461026
787159	taxon:9606	2.4362691	117.4801184	0.00117922	179955	1902	LDL receptor related protein 1	gene	biological_process-&-1&-GO:0032374-&&-regulation of cholesterol transport-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0032370-&&-positive regulation of lipid transport-%%-GO:0007568-&&-aging-%%-GO:0008283-&&-cell proliferation-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0051222-&&-positive regulation of protein transport-%%-GO:0010715-&&-regulation of extracellular matrix disassembly-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0032429-&&-regulation of phospholipase A2 activity-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0097242-&&-beta-amyloid clearance-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005730-&&-nucleolus-%%-GO:0043235-&&-receptor complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0042954-&&-lipoprotein transporter activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005041-&&-low-density lipoprotein receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0070325-&&-lipoprotein particle receptor binding-%%-GO:0004872-&&-receptor activity	G:9606:LRP1			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa05010-&&-Alzheimer disease-%%-hsa05144-&&-Malaria	LRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRP1	0.455164586	0.41046369	0.05109127	66	4	0.004582405	FALSE	7.28	LRP1	LRP1	106.15625	7.622294372	0	65	0	0.76062182	FALSE	1	LRP1	1150256	Infinity	0.03011743
791435	taxon:9606	2.42004096	354.0123028	1.59E-04	168660	1902	WNK lysine deficient protein kinase 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0023016-&&-signal transduction by trans-phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0090188-&&-negative regulation of pancreatic juice secretion-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0006811-&&-ion transport-%%-GO:0050794-&&-regulation of cellular process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0003084-&&-positive regulation of systemic arterial blood pressure-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0048666-&&-neuron development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019870-&&-potassium channel inhibitor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019869-&&-chloride channel inhibitor activity	G:9606:WNK1				WNK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WNK1	0.481537076	0.41321615	0.1046627	66	4	0.007689803	FALSE	9.404761905	WNK1	WNK1	145.890625	9.687532975	0	65	0	0.76332651	FALSE	1	WNK1	255560	Infinity	0.04003826
787402	taxon:9606	2.43343312	437.5837731	5.95E-05	179488	1902	nucleosome assembly protein 1 like 4	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:NAP1L4				NAP1L4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAP1L4	0.485619134	0.41094205	0.17956349	66	4	0.015399416	FALSE	13.86206897	NAP1L4	NAP1L4	215.625	14.30048582	0	65	0	0.76109448	FALSE	1	NAP1L4	171954	Infinity	0.06021363
791577	taxon:9606	2.53426816	425.1592824	1.23E-04	167943	1902	centrosomal protein 290	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0030902-&&-hindbrain development-%%-GO:0060271-&&-cilium assembly-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0048793-&&-pronephros development-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0035580-&&-specific granule lumen-%%-GO:0036038-&&-MKS complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0034451-&&-centriolar satellite-%%-GO:0005814-&&-centriole-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP290				CEP290	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP290	0.461449942	0.39459123	0.1048951	66	4	0.005813458	FALSE	6.829268293	CEP290	CEP290	106.8636364	7.071212121	0	66	0	0.74428864	FALSE	0	CEP290	187382	Infinity	0.03627509
791793	taxon:9606	2.55254451	368.1960117	1.86E-04	166851	1902	WD repeat domain 83	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0010008-&&-endosome membrane-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WDR83				WDR83	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR83	0.44955157	0.39176594	0.07925408	66	5	0.006185144	FALSE	6.571428571	WDR83	WDR83	110.7575758	6.780559541	0	66	0	0.74124258	FALSE	0	WDR83	244448	Infinity	0.03927234
787802	taxon:9606	2.42382228	234.7178723	1.92E-04	162380	1902	forkhead box K1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0007517-&&-muscle organ development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:FOXK1				FOXK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXK1	0.483569491	0.4125715	0.09417249	66	4	0.006503181	FALSE	7.611111111	FOXK1	FOXK1	131.8787879	7.828571429	0	66	0	0.76269629	FALSE	0	FOXK1	263432	Infinity	0.03615835
791909	taxon:9606	2.35733417	449.2558746	1.56E-04	182889	1902	adenosylhomocysteinase	gene	biological_process-&-1&-GO:0019510-&&-S-adenosylhomocysteine catabolic process-%%-GO:0071268-&&-homocysteine biosynthetic process-%%-GO:0042745-&&-circadian sleep/wake cycle-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0002439-&&-chronic inflammatory response to antigenic stimulus-%%-GO:0007584-&&-response to nutrient-%%-GO:0000096-&&-sulfur amino acid metabolic process-%%-GO:0032259-&&-methylation-%%-GO:0033353-&&-S-adenosylmethionine cycle-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0030554-&&-adenyl nucleotide binding-%%-GO:0005515-&&-protein binding-%%-GO:0004013-&&-adenosylhomocysteinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0051287-&&-NAD binding	G:9606:AHCY			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways	AHCY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHCY	0.492931776	0.42420799	0.12003968	66	4	0.014048643	FALSE	10.69230769	AHCY	AHCY	228.5	11.22339382	0	65	0	0.77377764	FALSE	1	AHCY	296376	Infinity	0.05657434
791933	taxon:9606	2.51756735	201.3944067	2.25E-04	182854	1902	anaplastic lymphoma receptor tyrosine kinase	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0021766-&&-hippocampus development-%%-GO:0036269-&&-swimming behavior-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway-%%-GO:0048666-&&-neuron development-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0030534-&&-adult behavior-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0008283-&&-cell proliferation-%%-GO:0016310-&&-phosphorylation-%%-GO:0090648-&&-response to environmental enrichment-%%-GO:0000187-&&-activation of MAPK activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ALK			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa05200-&&-Pathways in cancer	ALK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALK	0.454519694	0.39720884	0.09077381	66	4	0.006628135	FALSE	9.789473684	ALK	ALK	118.78125	10.06946653	0	65	0	0.74707211	FALSE	1	ALK	260146	Infinity	0.03926415
791970	taxon:9606	2.41547188	521.4841307	1.38E-04	182784	1902	amyloid beta precursor protein binding family B member 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0050760-&&-negative regulation of thymidylate synthase biosynthetic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010039-&&-response to iron ion-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0007409-&&-axonogenesis-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0045739-&&-positive regulation of DNA repair|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:1990761-&&-growth cone lamellipodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0016607-&&-nuclear speck-%%-GO:0044304-&&-main axon-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0045202-&&-synapse-%%-GO:1990812-&&-growth cone filopodium-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0042393-&&-histone binding	G:9606:APBB1			KEGG-&-1&-hsa05010-&&-Alzheimer disease	APBB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APBB1	0.480671262	0.41399778	0.11210317	66	4	0.010329809	FALSE	9.92	APBB1	APBB1	154.46875	10.42644892	0	65	0	0.76408802	FALSE	1	APBB1	236686	Infinity	0.04198953
787901	taxon:9606	2.52056089	269.8418276	9.41E-05	178642	1902	proteasome 26S subunit, non-ATPase 5	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070682-&&-proteasome regulatory particle assembly-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process|cellular_component-&-1&-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PSMD5				PSMD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD5	0.456589809	0.39673709	0.34685315	66	4	0.007072266	FALSE	27.95833333	PSMD5	PSMD5	124.0909091	28.61373442	0	66	0	0.74657318	FALSE	0	PSMD5	147360	Infinity	0.04130441
787974	taxon:9606	2.42933669	540.5856546	8.25E-05	178482	1902	phosphoenolpyruvate carboxykinase 1	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0071332-&&-cellular response to fructose stimulus-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0046327-&&-glycerol biosynthetic process from pyruvate-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0032868-&&-response to insulin-%%-GO:1904640-&&-response to methionine-%%-GO:0070741-&&-response to interleukin-6-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0051365-&&-cellular response to potassium ion starvation-%%-GO:0007568-&&-aging-%%-GO:0061402-&&-positive regulation of transcription from RNA polymerase II promoter in response to acidic pH-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006107-&&-oxaloacetate metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004613-&&-phosphoenolpyruvate carboxykinase (GTP) activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031406-&&-carboxylic acid binding-%%-GO:0019003-&&-GDP binding	G:9606:PCK1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03320-&&-PPAR signaling pathway	PCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCK1	0.484153335	0.411635	0.12121212	66	4	0.012205415	FALSE	9.033898305	PCK1	PCK1	160.0151515	9.362631175	0	66	0	0.76177722	FALSE	0	PCK1	177620	Infinity	0.04478011
792225	taxon:9606	2.46242319	400.2153746	2.19E-04	182387	1902	ATPase Na+/K+ transporting subunit beta 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:0050821-&&-protein stabilization-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:1903281-&&-positive regulation of calcium:sodium antiporter activity-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0010107-&&-potassium ion import-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0007155-&&-cell adhesion-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086009-&&-membrane repolarization-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:1990573-&&-potassium ion import across plasma membrane-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:0046034-&&-ATP metabolic process-%%-GO:1903288-&&-positive regulation of potassium ion import-%%-GO:0044861-&&-protein transport into plasma membrane raft-%%-GO:1903278-&&-positive regulation of sodium ion export from cell-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0001666-&&-response to hypoxia-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0042383-&&-sarcolemma-%%-GO:0005901-&&-caveola-%%-GO:0016020-&&-membrane-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0014704-&&-intercalated disc-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0031402-&&-sodium ion binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0008144-&&-drug binding	G:9606:ATP1B1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04978-&&-Mineral absorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04976-&&-Bile secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1B1	0.474135383	0.40610404	0.08717949	66	4	0.006372821	FALSE	5.487179487	ATP1B1	ATP1B1	122.8636364	5.731239504	0	66	0	0.7562628	FALSE	0	ATP1B1	288060	Infinity	0.03627764
792574	taxon:9606	2.4394202	206.972625	1.10E-04	181789	1902	cyclin E1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0000723-&&-telomere maintenance-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007129-&&-synapsis-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0051726-&&-regulation of cell cycle|cellular_component-&-1&-GO:0097134-&&-cyclin E1-CDK2 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity	G:9606:CCNE1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05226-&&-Gastric cancer	CCNE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNE1	0.48371532	0.40993348	0.14871795	66	4	0.009358769	FALSE	10.58695652	CCNE1	CCNE1	153.0151515	10.84834055	0	66	0	0.76009663	FALSE	0	CCNE1	191658	Infinity	0.0433305
792728	taxon:9606	2.46841027	90.88119128	5.42E-04	181490	1902	discs large MAGUK scaffold protein 4	gene	biological_process-&-1&-GO:0071625-&&-vocalization behavior-%%-GO:0007612-&&-learning-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0097120-&&-receptor localization to synapse-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0035418-&&-protein localization to synapse-%%-GO:0035176-&&-social behavior-%%-GO:0006461-&&-protein complex assembly-%%-GO:0002091-&&-negative regulation of receptor internalization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0046710-&&-GDP metabolic process-%%-GO:2000821-&&-regulation of grooming behavior-%%-GO:0097113-&&-AMPA glutamate receptor clustering-%%-GO:0007268-&&-chemical synaptic transmission|cellular_component-&-1&-GO:0030863-&&-cortical cytoskeleton-%%-GO:0044306-&&-neuron projection terminus-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0030054-&&-cell junction-%%-GO:0098839-&&-postsynaptic density membrane-%%-GO:0044300-&&-cerebellar mossy fiber-%%-GO:0005829-&&-cytosol-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0045202-&&-synapse-%%-GO:0043197-&&-dendritic spine-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0044309-&&-neuron spine-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0044224-&&-juxtaparanode region of axon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0060076-&&-excitatory synapse-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0031812-&&-P2Y1 nucleotide receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0033130-&&-acetylcholine receptor binding-%%-GO:0097109-&&-neuroligin family protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031697-&&-beta-1 adrenergic receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019900-&&-kinase binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0015276-&&-ligand-gated ion channel activity	G:9606:DLG4			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05016-&&-Huntington disease-%%-hsa05030-&&-Cocaine addiction	DLG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLG4	0.45349166	0.40511904	0.08184524	66	4	0.004034192	FALSE	6.5	DLG4	DLG4	104.859375	6.80952381	0	65	0	0.75526495	FALSE	1	DLG4	507478	Infinity	0.0314233
788634	taxon:9606	2.53804947	234.9326284	1.19E-04	177282	1902	transcription factor AP-4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:2001269-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:TFAP4			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	TFAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFAP4	0.46091954	0.39400335	0.09230769	66	4	0.006939318	FALSE	7.051282051	TFAP4	TFAP4	119.8787879	7.256578947	0	66	0	0.74365842	FALSE	0	TFAP4	191214	Infinity	0.04087963
788647	taxon:9606	2.3067591	461.4685992	3.96E-04	177252	1902	transferrin receptor	gene	biological_process-&-1&-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0061024-&&-membrane organization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0031623-&&-receptor internalization-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0033572-&&-transferrin transport-%%-GO:0045830-&&-positive regulation of isotype switching-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0097286-&&-iron ion import-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0045780-&&-positive regulation of bone resorption|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:1990712-&&-HFE-transferrin receptor complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0016020-&&-membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004998-&&-transferrin receptor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0033570-&&-transferrin transmembrane transporter activity	G:9606:TFRC			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04145-&&-Phagosome-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04216-&&-Ferroptosis-%%-hsa04066-&&-HIF-1 signaling pathway	TFRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFRC	0.49247774	0.43350864	0.08630952	66	4	0.012535464	FALSE	8.914893617	TFRC	TFRC	234.34375	9.247872754	0	65	0	0.78220682	FALSE	1	TFRC	603134	Infinity	0.05399954
788809	taxon:9606	2.47219159	425.5096666	2.49E-04	176834	1902	tyrosine kinase 2	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0005131-&&-growth hormone receptor binding	G:9606:TYK2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	TYK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TYK2	0.46655032	0.40449939	0.11061508	66	4	0.008502496	FALSE	9.62	TYK2	TYK2	133.78125	10.10153177	0	65	0	0.75463474	FALSE	1	TYK2	398402	Infinity	0.0404548
788893	taxon:9606	2.40995746	200.7195474	2.15E-04	176661	1902	X-ray repair cross complementing 1	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0010033-&&-response to organic substance-%%-GO:0061819-&&-telomeric DNA-containing double minutes formation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006288-&&-base-excision repair, DNA ligation-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000012-&&-single strand break repair-%%-GO:0042493-&&-response to drug-%%-GO:1905765-&&-negative regulation of protection from non-homologous end joining at telomere-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0070522-&&-ERCC4-ERCC1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:1990599-&&-3' overhang single-stranded DNA endodeoxyribonuclease activity	G:9606:XRCC1			KEGG-&-1&-hsa03410-&&-Base excision repair	XRCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRCC1	0.484738592	0.41494508	0.11188811	66	4	0.009484214	FALSE	7.897435897	XRCC1	XRCC1	171.7424242	8.105263158	0	66	0	0.76500709	FALSE	0	XRCC1	343494	Infinity	0.04632537
789027	taxon:9606	2.44146841	362.8156083	4.56E-05	176347	1902	RNA binding motif protein 10	gene	biological_process-&-1&-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006397-&&-mRNA processing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:RBM10				RBM10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM10	0.488131467	0.40958957	0.22371032	66	4	0.017752314	FALSE	16.11864407	RBM10	RBM10	240.109375	16.5018007	0	65	0	0.75975526	FALSE	1	RBM10	153732	Infinity	0.06820845
789064	taxon:9606	2.58232236	258.0654305	5.95E-05	176259	1902	barrier to autointegration factor 1	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0009615-&&-response to virus-%%-GO:0051169-&&-nuclear transport-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0015074-&&-DNA integration|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0097726-&&-LEM domain binding	G:9606:BANF1				BANF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BANF1	0.463583815	0.38724832	0.19642857	66	4	0.012498464	FALSE	16.98039216	BANF1	BANF1	165.296875	17.34107314	0	65	0	0.73627961	FALSE	1	BANF1	142618	Infinity	0.06212392
789111	taxon:9606	2.49440681	409.3550409	2.68E-04	176173	1902	B-cell CLL/lymphoma 10	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0042226-&&-interleukin-6 biosynthetic process-%%-GO:0009620-&&-response to fungus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032094-&&-response to food-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:0002250-&&-adaptive immune response-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0050856-&&-regulation of T cell receptor signaling pathway-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032765-&&-positive regulation of mast cell cytokine production-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051259-&&-protein oligomerization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008219-&&-cell death-%%-GO:0042109-&&-lymphotoxin A biosynthetic process-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0006968-&&-cellular defense response-%%-GO:0045087-&&-innate immune response-%%-GO:0002906-&&-negative regulation of mature B cell apoptotic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0070231-&&-T cell apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0046696-&&-lipopolysaccharide receptor complex-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0032449-&&-CBM complex-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019209-&&-kinase activator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0043621-&&-protein self-association	G:9606:BCL10			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	BCL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL10	0.468321168	0.40089692	0.10565476	66	4	0.006586912	FALSE	9.466666667	BCL10	BCL10	129.671875	9.752216262	0	65	0	0.7509322	FALSE	1	BCL10	356564	Infinity	0.04103916
789300	taxon:9606	2.75500236	75.74728809	8.11E-05	175795	1902	mediator complex subunit 26	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:MED26				MED26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED26	0.397521685	0.3629761	0.25128205	66	4	0.002338543	FALSE	9.56	MED26	MED26	65.46969697	9.958333333	0	66	0	0.70749961	FALSE	0	MED26	96250	Infinity	0.04027972
789335	taxon:9606	2.5041752	237.8649504	1.83E-04	175708	1902	Fas associated via death domain	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2000454-&&-positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0048535-&&-lymph node development-%%-GO:0070236-&&-negative regulation of activation-induced cell death of T cells-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0001916-&&-positive regulation of T cell mediated cytotoxicity-%%-GO:0036462-&&-TRAIL-activated apoptotic signaling pathway-%%-GO:0002821-&&-positive regulation of adaptive immune response-%%-GO:0048538-&&-thymus development-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097049-&&-motor neuron apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0043278-&&-response to morphine-%%-GO:0048536-&&-spleen development-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0044297-&&-cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0097342-&&-ripoptosome|molecular_function-&-1&-GO:0032813-&&-tumor necrosis factor receptor superfamily binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0033612-&&-receptor serine/threonine kinase binding-%%-GO:0035877-&&-death effector domain binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0089720-&&-caspase binding	G:9606:FADD			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	FADD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FADD	0.464254703	0.39933308	0.12103175	66	4	0.004992505	FALSE	10.02702703	FADD	FADD	103.921875	10.31349206	0	65	0	0.74930413	FALSE	1	FADD	233538	Infinity	0.03329893
789743	taxon:9606	2.40538837	499.1275753	1.70E-04	174783	1902	ubiquitin like modifier activating enzyme 2	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031510-&&-SUMO activating enzyme complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019948-&&-SUMO activating enzyme activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:UBA2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA2	0.485619134	0.41573328	0.11282051	66	4	0.008176643	FALSE	7.895833333	UBA2	UBA2	150.969697	8.206349014	0	66	0	0.7657686	FALSE	0	UBA2	255868	Infinity	0.0404338
789746	taxon:9606	2.40491571	246.7714432	1.54E-04	174773	1902	ARP3 actin related protein 3 homolog	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0016344-&&-meiotic chromosome movement towards spindle pole-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051653-&&-spindle localization-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0060271-&&-cilium assembly-%%-GO:0033206-&&-meiotic cytokinesis|cellular_component-&-1&-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016020-&&-membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005903-&&-brush border|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:ACTR3			KEGG-&-1&-hsa04530-&&-Tight junction	ACTR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTR3	0.485766202	0.41581499	0.18414918	66	4	0.010112387	FALSE	12.375	ACTR3	ACTR3	180.1060606	12.78807859	0	66	0	0.76584738	FALSE	0	ACTR3	276516	Infinity	0.04824294
789913	taxon:9606	2.36773279	240.3253971	7.19E-05	174379	1902	insulin like growth factor 2 mRNA binding protein 3	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0010467-&&-gene expression-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0042035-&&-regulation of cytokine biosynthetic process-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:IGF2BP3				IGF2BP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2BP3	0.49247774	0.42234496	0.28018648	66	4	0.017997433	FALSE	17.84615385	IGF2BP3	IGF2BP3	248.8181818	18.22927323	0	66	0	0.77204454	FALSE	0	IGF2BP3	180076	Infinity	0.06265501
790072	taxon:9606	2.47833622	233.7773002	3.58E-04	173941	1902	Ras association domain family member 1	gene	biological_process-&-1&-GO:0007050-&&-cell cycle arrest-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:RASSF1	RASSF1	TRUE	KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05200-&&-Pathways in cancer	RASSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF1	0.469692533	0.4034965	0.09176587	66	4	0.007112995	FALSE	9.868421053	RASSF1	RASSF1	127.734375	10.16756757	0	65	0	0.75361063	FALSE	1	RASSF1	422000	Infinity	0.03900038
790205	taxon:9606	2.59681739	185.7240168	7.51E-05	173637	1902	PHD finger protein 8	gene	biological_process-&-1&-GO:0061188-&&-negative regulation of chromatin silencing at rDNA-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0007420-&&-brain development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071557-&&-histone H3-K27 demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0035574-&&-histone H4-K20 demethylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070544-&&-histone H3-K36 demethylation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0035064-&&-methylated histone binding-%%-GO:0051864-&&-histone demethylase activity (H3-K36 specific)-%%-GO:0035575-&&-histone demethylase activity (H4-K20 specific)-%%-GO:0071558-&&-histone demethylase activity (H3-K27 specific)-%%-GO:0008270-&&-zinc ion binding	G:9606:PHF8				PHF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF8	0.441873278	0.38508676	0.20839161	66	4	0.013112072	FALSE	15.79591837	PHF8	PHF8	176.7727273	16.17040421	0	66	0	0.73386377	FALSE	0	PHF8	175330	Infinity	0.06887267
790692	taxon:9606	2.48904994	392.9974236	7.11E-05	171460	1902	tropomodulin 3	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0048821-&&-erythrocyte development-%%-GO:1901992-&&-positive regulation of mitotic cell cycle phase transition-%%-GO:0051694-&&-pointed-end actin filament capping-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0005865-&&-striated muscle thin filament-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005523-&&-tropomyosin binding	G:9606:TMOD3				TMOD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMOD3	0.483569491	0.40175972	0.18942308	65	4	0.014964323	FALSE	13.85714286	TMOD3	TMOD3	210.6153846	14.24558187	0	65	0	0.75182501	FALSE	0	TMOD3	201640	Infinity	0.06536313
790921	taxon:9606	2.34614779	452.2109778	1.28E-04	170699	1902	serrate, RNA effector molecule	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008283-&&-cell proliferation-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:SRRT				SRRT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRRT	0.496748219	0.42623061	0.14615385	65	4	0.013625168	FALSE	10.83018868	SRRT	SRRT	215	11.24701294	0	65	0	0.77564204	FALSE	0	SRRT	240316	Infinity	0.05223144
791272	taxon:9606	2.53741925	369.4875443	1.53E-04	169417	1902	mitochondrial antiviral signaling protein	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0007165-&&-signal transduction-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0039529-&&-RIG-I signaling pathway-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0071651-&&-positive regulation of chemokine (C-C motif) ligand 5 production-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071660-&&-positive regulation of IP-10 production-%%-GO:0051607-&&-defense response to virus-%%-GO:1900063-&&-regulation of peroxisome organization-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0050700-&&-CARD domain binding	G:9606:MAVS			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B	MAVS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAVS	0.459598854	0.39410121	0.11776754	65	4	0.005608158	FALSE	10.42857143	MAVS	MAVS	111.4920635	10.83904837	0	64	0	0.74376346	FALSE	1	MAVS	200350	Infinity	0.03843142
791332	taxon:9606	2.56499133	243.8854286	1.96E-04	169117	1902	tripartite motif containing 54	gene	biological_process-&-1&-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0007165-&&-signal transduction-%%-GO:0055001-&&-muscle cell development-%%-GO:0007017-&&-microtubule-based process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0030018-&&-Z disc-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM54				TRIM54	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM54	0.442116869	0.38986486	0.04710701	65	4	0.003886793	FALSE	6.151515152	TRIM54	TRIM54	88.14285714	6.34375	0	64	0	0.73916811	FALSE	1	TRIM54	222132	Infinity	0.03204094
791329	taxon:9606	2.45202458	515.2349686	2.36E-04	169132	1902	reticulon 4	gene	biological_process-&-1&-GO:0007413-&&-axonal fasciculation-%%-GO:0071786-&&-endoplasmic reticulum tubular network organization-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0071787-&&-endoplasmic reticulum tubular network formation-%%-GO:0006915-&&-apoptotic process-%%-GO:0021801-&&-cerebral cortex radial glia guided migration-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:2000172-&&-regulation of branching morphogenesis of a nerve|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RTN4			KEGG-&-1&-hsa05010-&&-Alzheimer disease	RTN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RTN4	0.481248125	0.40782625	0.06502816	65	4	0.007244167	FALSE	7.452380952	RTN4	RTN4	139.2698413	7.765789041	0	64	0	0.7579959	FALSE	1	RTN4	318294	Infinity	0.04041074
787473	taxon:9606	2.45549078	375.453447	2.19E-04	179361	1902	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0033033-&&-negative regulation of myeloid cell apoptotic process-%%-GO:0061081-&&-positive regulation of myeloid leukocyte cytokine production involved in immune response-%%-GO:0050900-&&-leukocyte migration-%%-GO:0019752-&&-carboxylic acid metabolic process-%%-GO:0010739-&&-positive regulation of protein kinase A signaling-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0007569-&&-cell aging-%%-GO:0043030-&&-regulation of macrophage activation-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0006954-&&-inflammatory response-%%-GO:2000343-&&-positive regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0002906-&&-negative regulation of mature B cell apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0061078-&&-positive regulation of prostaglandin secretion involved in immune response-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:0090344-&&-negative regulation of cell aging-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0090238-&&-positive regulation of arachidonic acid secretion-%%-GO:0032269-&&-negative regulation of cellular protein metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005126-&&-cytokine receptor binding-%%-GO:0004167-&&-dopachrome isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0050178-&&-phenylpyruvate tautomerase activity	G:9606:MIF	MIF	TRUE	KEGG-&-1&-hsa00350-&&-Tyrosine metabolism-%%-hsa00360-&&-Phenylalanine metabolism	MIF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MIF	0.478663086	0.40725056	0.11827957	65	4	0.010189149	FALSE	10.28888889	MIF	MIF	169.7142857	10.66916333	0	64	0	0.7574182	FALSE	1	MIF	329720	Infinity	0.04963976
791802	taxon:9606	2.81345518	34.32262535	9.80E-05	166799	1902	chromosome 15 open reading frame 48	gene	biological_process-&-1&-GO:1902600-&&-hydrogen ion transmembrane transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005751-&&-mitochondrial respiratory chain complex IV|molecular_function-&-1&-GO:0004129-&&-cytochrome-c oxidase activity	G:9606:C15orf48				C15orf48	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C15orf48	0.369329956	0.35543484	0.11730769	65	4	0.001488725	FALSE	5	C15orf48	C15orf48	45.52307692	5.3125	0	65	0	0.69775747	FALSE	0	C15orf48	124670	Infinity	0.03712402
791819	taxon:9606	2.53568615	263.4935706	1.65E-04	166710	1902	tripartite motif containing 63	gene	biological_process-&-1&-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0007165-&&-signal transduction-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006936-&&-muscle contraction|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0031432-&&-titin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0004871-&&-signal transducer activity	G:9606:TRIM63				TRIM63	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM63	0.448545861	0.39437057	0.07526882	65	4	0.004694537	FALSE	7.135135135	TRIM63	TRIM63	98.22222222	7.378472222	0	64	0	0.74405231	FALSE	1	TRIM63	207500	Infinity	0.0336384
787775	taxon:9606	2.49740035	209.8409402	2.69E-04	178800	1902	protein phosphatase 3 catalytic subunit alpha	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0035690-&&-cellular response to drug-%%-GO:0051592-&&-response to calcium ion-%%-GO:0016311-&&-dephosphorylation-%%-GO:0006816-&&-calcium ion transport-%%-GO:0035562-&&-negative regulation of chromatin binding-%%-GO:0001975-&&-response to amphetamine-%%-GO:1903244-&&-positive regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0042110-&&-T cell activation-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0033555-&&-multicellular organismal response to stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0014883-&&-transition between fast and slow fiber-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:1905205-&&-positive regulation of connective tissue replacement-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0048741-&&-skeletal muscle fiber development|cellular_component-&-1&-GO:0005955-&&-calcineurin complex-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse-%%-GO:0042383-&&-sarcolemma-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008144-&&-drug binding-%%-GO:0033192-&&-calmodulin-dependent protein phosphatase activity	G:9606:PPP3CA	PPP3CA	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP3CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP3CA	0.45581131	0.40041638	0.05529954	65	4	0.00457636	FALSE	5.733333333	PPP3CA	PPP3CA	101.1428571	5.931034483	0	64	0	0.75043328	FALSE	1	PPP3CA	300488	Infinity	0.03197709
791917	taxon:9606	2.36962344	141.5274063	3.34E-04	182877	1902	AKT serine/threonine kinase 2	gene	biological_process-&-1&-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0008643-&&-carbohydrate transport-%%-GO:0065002-&&-intracellular protein transmembrane transport-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0071486-&&-cellular response to high light intensity-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0097473-&&-retinal rod cell apoptotic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0010748-&&-negative regulation of plasma membrane long-chain fatty acid transport-%%-GO:0071156-&&-regulation of cell cycle arrest-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0006417-&&-regulation of translation-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0007165-&&-signal transduction-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:AKT2	AKT2	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	AKT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKT2	0.474275577	0.42200798	0.11623144	65	4	0.009758992	FALSE	12.64864865	AKT2	AKT2	184.1428571	13.00980392	0	64	0	0.77172943	FALSE	1	AKT2	480904	Infinity	0.0464495
787890	taxon:9606	2.66283283	272.5610498	7.20E-05	178655	1902	proteasome subunit beta 9	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:2000116-&&-regulation of cysteine-type endopeptidase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1990111-&&-spermatoproteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB9			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB9	0.434100135	0.37553991	0.40757808	65	4	0.005966933	FALSE	28.67391304	PSMB9	PSMB9	103.5873016	29.36862745	0	64	0	0.72286119	FALSE	1	PSMB9	96218	Infinity	0.0480387
788217	taxon:9606	2.41562943	393.911621	2.39E-04	178057	1902	ret proto-oncogene	gene	biological_process-&-1&-GO:1903263-&&-positive regulation of serine phosphorylation of STAT3 protein-%%-GO:0042551-&&-neuron maturation-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001838-&&-embryonic epithelial tube formation-%%-GO:0007158-&&-neuron cell-cell adhesion-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0033619-&&-membrane protein proteolysis-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0007497-&&-posterior midgut development-%%-GO:0048265-&&-response to pain-%%-GO:0097021-&&-lymphocyte migration into lymphoid organs-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0072300-&&-positive regulation of metanephric glomerulus development-%%-GO:0035799-&&-ureter maturation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0061146-&&-Peyer's patch morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0060384-&&-innervation-%%-GO:0048484-&&-enteric nervous system development-%%-GO:0007411-&&-axon guidance-%%-GO:0001657-&&-ureteric bud development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0043235-&&-receptor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0010008-&&-endosome membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005769-&&-early endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004872-&&-receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:RET			KEGG-&-1&-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	RET	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RET	0.471071953	0.41397078	0.14336918	65	4	0.009654235	FALSE	12.26829268	RET	RET	194.5079365	12.64844828	0	64	0	0.76406176	FALSE	1	RET	421014	Infinity	0.05311822
788244	taxon:9606	2.53615882	298.8824628	2.67E-04	178015	1902	siah E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006915-&&-apoptotic process-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007049-&&-cell cycle-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007411-&&-axon guidance-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0008270-&&-zinc ion binding	G:9606:SIAH2				SIAH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIAH2	0.460126219	0.39429707	0.06554019	65	4	0.004850364	FALSE	7.27027027	SIAH2	SIAH2	100.6666667	7.486111111	0	64	0	0.74397353	FALSE	1	SIAH2	312200	Infinity	0.03440058
792607	taxon:9606	2.48589885	240.4363488	1.47E-04	181731	1902	deoxyuridine triphosphatase	gene	biological_process-&-1&-GO:0046134-&&-pyrimidine nucleoside biosynthetic process-%%-GO:0046080-&&-dUTP metabolic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0006260-&&-DNA replication-%%-GO:0006226-&&-dUMP biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004170-&&-dUTP diphosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:DUT			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	DUT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUT	0.472320377	0.40226898	0.13056836	65	4	0.008265628	FALSE	10.65	DUT	DUT	134.7460318	10.95606002	0	64	0	0.75235019	FALSE	1	DUT	218862	Infinity	0.04156076
788529	taxon:9606	2.50165432	201.3905856	1.55E-04	177496	1902	thyroid hormone receptor beta	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0060509-&&-Type I pneumocyte differentiation-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008050-&&-female courtship behavior-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0007621-&&-negative regulation of female receptivity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070324-&&-thyroid hormone binding	G:9606:THRB			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	THRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRB	0.466821886	0.39973548	0.124936	65	4	0.007219934	FALSE	11.5	THRB	THRB	129.6031746	11.7942464	0	64	0	0.74972428	FALSE	1	THRB	239636	Infinity	0.04113081
792734	taxon:9606	2.44903104	411.8985694	1.89E-04	181477	1902	dynamin 1	gene	biological_process-&-1&-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0061025-&&-membrane fusion-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051932-&&-synaptic transmission, GABAergic-%%-GO:0000266-&&-mitochondrial fission-%%-GO:1901998-&&-toxin transport-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006897-&&-endocytosis-%%-GO:0016185-&&-synaptic vesicle budding from presynaptic endocytic zone membrane-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007032-&&-endosome organization-%%-GO:0051262-&&-protein tetramerization-%%-GO:1903423-&&-positive regulation of synaptic vesicle recycling|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0043196-&&-varicosity-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0030117-&&-membrane coat-%%-GO:0001917-&&-photoreceptor inner segment|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0031749-&&-D2 dopamine receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003924-&&-GTPase activity	G:9606:DNM1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04721-&&-Synaptic vesicle cycle	DNM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNM1	0.472877358	0.40832476	0.07834101	65	4	0.005912076	FALSE	7.333333333	DNM1	DNM1	130.8888889	7.678557043	0	64	0	0.75849483	FALSE	1	DNM1	289614	Infinity	0.0379222
788623	taxon:9606	2.44272885	314.7181716	8.70E-05	177289	1902	telomerase reverse transcriptase	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:1903704-&&-negative regulation of production of siRNA involved in RNA interference-%%-GO:0001172-&&-transcription, RNA-templated-%%-GO:0022616-&&-DNA strand elongation-%%-GO:0090399-&&-replicative senescence-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0006278-&&-RNA-dependent DNA biosynthetic process-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1903620-&&-positive regulation of transdifferentiation-%%-GO:0030422-&&-production of siRNA involved in RNA interference-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:1904751-&&-positive regulation of protein localization to nucleolus-%%-GO:0007005-&&-mitochondrion organization-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0032774-&&-RNA biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0042635-&&-positive regulation of hair cycle|cellular_component-&-1&-GO:1990572-&&-TERT-RMRP complex-%%-GO:0000333-&&-telomerase catalytic core complex-%%-GO:0005730-&&-nucleolus-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0031379-&&-RNA-directed RNA polymerase complex-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0003721-&&-telomerase RNA reverse transcriptase activity-%%-GO:0016779-&&-nucleotidyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003968-&&-RNA-directed 5'-3' RNA polymerase activity-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0003720-&&-telomerase activity-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003964-&&-RNA-directed DNA polymerase activity-%%-GO:0000049-&&-tRNA binding	G:9606:TERT			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer-%%-hsa05165-&&-Human papillomavirus infection	TERT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERT	0.485178463	0.40937822	0.11674347	65	4	0.010923411	FALSE	10.24074074	TERT	TERT	165.1587302	10.47851649	0	64	0	0.75954519	FALSE	1	TERT	164646	Infinity	0.04713873
792797	taxon:9606	2.42461005	300.3790513	1.59E-04	181352	1902	eukaryotic translation initiation factor 4E	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006417-&&-regulation of translation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006413-&&-translational initiation-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0001662-&&-behavioral fear response-%%-GO:0030324-&&-lung development-%%-GO:0016032-&&-viral process-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0033391-&&-chromatoid body-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005845-&&-mRNA cap binding complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031370-&&-eukaryotic initiation factor 4G binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0019899-&&-enzyme binding	G:9606:EIF4E			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa03013-&&-RNA transport-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	EIF4E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4E	0.480671262	0.41243746	0.10650282	65	4	0.008198628	FALSE	9.813953488	EIF4E	EIF4E	140.5238095	10.13307289	0	64	0	0.76256499	FALSE	1	EIF4E	226172	Infinity	0.03891506
792816	taxon:9606	2.41389633	218.2863028	1.57E-04	181323	1902	microtubule affinity regulating kinase 2	gene	biological_process-&-1&-GO:0030010-&&-establishment of cell polarity-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0001764-&&-neuron migration-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0000422-&&-mitophagy-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0051646-&&-mitochondrion localization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005884-&&-actin filament-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0097427-&&-microtubule bundle-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030295-&&-protein kinase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0050321-&&-tau-protein kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:MARK2				MARK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARK2	0.480383348	0.414268	0.13620072	65	4	0.008506709	FALSE	11.3902439	MARK2	MARK2	164.8412698	11.69932432	0	64	0	0.76435061	FALSE	1	MARK2	250154	Infinity	0.04461465
788851	taxon:9606	2.41090279	291.5917392	2.67E-04	176749	1902	vasodilator-stimulated phosphoprotein	gene	biological_process-&-1&-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0001843-&&-neural tube closure-%%-GO:0034329-&&-cell junction assembly-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0031258-&&-lamellipodium membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005522-&&-profilin binding	G:9606:VASP			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04611-&&-Platelet activation-%%-hsa04530-&&-Tight junction-%%-hsa04022-&&-cGMP-PKG signaling pathway	VASP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VASP	0.483569491	0.41478238	0.09165387	65	4	0.009245282	FALSE	8.75	VASP	VASP	154.0476191	9.018063187	0	64	0	0.76484954	FALSE	1	VASP	345478	Infinity	0.04167204
792979	taxon:9606	2.40979991	268.3774978	2.77E-04	181049	1902	forkhead box O1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001568-&&-blood vessel development-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:1902617-&&-response to fluoride-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0070417-&&-cellular response to cold-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0006473-&&-protein acetylation-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045722-&&-positive regulation of gluconeogenesis-%%-GO:0006914-&&-autophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035947-&&-regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter-%%-GO:2000177-&&-regulation of neural precursor cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0070166-&&-enamel mineralization-%%-GO:0071549-&&-cellular response to dexamethasone stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:FOXO1	FOXO1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence	FOXO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXO1	0.4769551	0.41497221	0.14900154	65	4	0.008856914	FALSE	13.61702128	FOXO1	FOXO1	169.2380952	14.07566126	0	64	0	0.76503335	FALSE	1	FOXO1	339866	Infinity	0.04560336
792976	taxon:9606	2.48763195	320.4171515	3.57E-05	164672	1902	splicing regulatory glutamic acid and lysine rich protein 1	gene	biological_process-&-1&-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SREK1				SREK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SREK1	0.483569491	0.40198873	0.22478239	65	4	0.015145514	FALSE	16.25	SREK1	SREK1	179.7619048	16.79335824	0	64	0	0.75206134	FALSE	1	SREK1	87722	Infinity	0.05551634
788948	taxon:9606	2.44225618	380.5637228	1.84E-04	176551	1902	O-linked N-acetylglucosamine (GlcNAc) transferase	gene	biological_process-&-1&-GO:0090526-&&-regulation of gluconeogenesis involved in cellular glucose homeostasis-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0032868-&&-response to insulin-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0007165-&&-signal transduction-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007584-&&-response to nutrient-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0061087-&&-positive regulation of histone H3-K27 methylation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0000123-&&-histone acetyltransferase complex|molecular_function-&-1&-GO:0016262-&&-protein N-acetylglucosaminyltransferase activity-%%-GO:0008375-&&-acetylglucosaminyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0097363-&&-protein O-GlcNAc transferase activity-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)	G:9606:OGT			KEGG-&-1&-hsa04931-&&-Insulin resistance-%%-hsa00514-&&-Other types of O-glycan biosynthesis	OGT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OGT	0.477096966	0.40945745	0.08448541	65	4	0.006849518	FALSE	7.243243243	OGT	OGT	136.4444444	7.61024531	0	64	0	0.75962397	FALSE	1	OGT	263312	Infinity	0.0387997
789152	taxon:9606	2.42980936	329.7772722	1.77E-04	176092	1902	protein inhibitor of activated STAT 2	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061665-&&-SUMO ligase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PIAS2			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	PIAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS2	0.476105669	0.41155492	0.1172555	65	4	0.007061763	FALSE	10.95348837	PIAS2	PIAS2	143.2380952	11.35923521	0	64	0	0.76169844	FALSE	1	PIAS2	260820	Infinity	0.03992599
789256	taxon:9606	2.43532378	219.4532755	5.47E-05	175890	1902	eukaryotic translation initiation factor 3 subunit B	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation-%%-GO:0075522-&&-IRES-dependent viral translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0032947-&&-protein complex scaffold-%%-GO:0003723-&&-RNA binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:EIF3B			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3B	0.484007242	0.41062302	0.21923077	65	4	0.014344475	FALSE	14.13207547	EIF3B	EIF3B	198.9076923	14.58176347	0	65	0	0.76077937	FALSE	0	EIF3B	150572	Infinity	0.05622038
789253	taxon:9606	2.43784465	277.9576412	6.94E-05	175889	1902	eukaryotic translation initiation factor 3 subunit C	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:EIF3C			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3C	0.483569491	0.41019841	0.22115385	65	4	0.014105617	FALSE	15.66	EIF3C	EIF3C	188.2769231	16.00816327	0	65	0	0.76035922	FALSE	0	EIF3C	165390	Infinity	0.05319625
789269	taxon:9606	2.50133922	463.9239965	2.42E-04	175861	1902	cell division cycle 23	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007091-&&-metaphase/anaphase transition of mitotic cell cycle-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:CDC23			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC23	0.464792814	0.39978584	0.11827957	65	4	0.005595056	FALSE	7.195121951	CDC23	CDC23	115	7.46613047	0	64	0	0.7497768	FALSE	1	CDC23	297572	Infinity	0.03660553
789454	taxon:9606	2.5456121	130.5794994	3.40E-04	175438	1902	BCL2 associated athanogene 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:1903215-&&-negative regulation of protein targeting to mitochondrion-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0097178-&&-ruffle assembly-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0090367-&&-negative regulation of mRNA modification-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2001145-&&-negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:BAG4			KEGG-&-1&-hsa04668-&&-TNF signaling pathway	BAG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG4	0.453363482	0.39283283	0.09038462	65	4	0.008218226	FALSE	10.22222222	BAG4	BAG4	128.6153846	10.63247863	0	65	0	0.74239798	FALSE	0	BAG4	405504	Infinity	0.04524281
789704	taxon:9606	2.30297778	771.4464837	1.56E-04	174858	1902	importin 7	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046332-&&-SMAD binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0042393-&&-histone binding	G:9606:IPO7				IPO7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO7	0.49751861	0.43422043	0.14759615	65	4	0.014208911	FALSE	11.07407407	IPO7	IPO7	242.5692308	11.67532209	0	65	0	0.78283704	FALSE	0	IPO7	345334	Infinity	0.05530183
789872	taxon:9606	2.64818024	332.7268558	1.90E-04	174470	1902	coiled-coil domain containing 85B	gene	biological_process-&-1&-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC85B				CCDC85B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC85B	0.428304406	0.3776178	0.03509615	65	4	0.003194252	FALSE	2.258064516	CCDC85B	CCDC85B	66.52307692	2.348941799	0	65	0	0.72530329	FALSE	0	CCDC85B	210858	Infinity	0.02984712
790028	taxon:9606	2.63352765	372.5237201	1.50E-04	174062	1902	midline 2	gene	biological_process-&-1&-GO:0010508-&&-positive regulation of autophagy-%%-GO:0045087-&&-innate immune response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0046597-&&-negative regulation of viral entry into host cell|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:MID2				MID2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MID2	0.43610658	0.37971882	0.08192524	65	4	0.004175669	FALSE	7.025641026	MID2	MID2	87.63492063	7.374713247	0	64	0	0.72774539	FALSE	1	MID2	196698	Infinity	0.03755207
790030	taxon:9606	2.4512368	204.6352873	5.14E-05	174058	1902	adhesion regulating molecule 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043248-&&-proteasome assembly-%%-GO:0010950-&&-positive regulation of endopeptidase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0061133-&&-endopeptidase activator activity-%%-GO:0070628-&&-proteasome binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:ADRM1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	ADRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRM1	0.473295958	0.40795732	0.48413462	65	4	0.009834992	FALSE	31.55932203	ADRM1	ADRM1	157.9846154	32.32392742	0	65	0	0.7581272	FALSE	0	ADRM1	125532	Infinity	0.0457484
790083	taxon:9606	2.36347881	418.0807409	1.42E-04	173917	1902	DEAD-box helicase 20	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006396-&&-RNA processing-%%-GO:0051170-&&-nuclear import-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050810-&&-regulation of steroid biosynthetic process-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0048477-&&-oogenesis-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0090571-&&-RNA polymerase II transcription repressor complex-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0016604-&&-nuclear body-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:DDX20			KEGG-&-1&-hsa03013-&&-RNA transport	DDX20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX20	0.487389851	0.42310513	0.15719406	65	4	0.009993363	FALSE	11.14285714	DDX20	DDX20	186.2539683	11.6672134	0	64	0	0.77275353	FALSE	1	DDX20	288122	Infinity	0.04652463
790368	taxon:9606	2.46746494	225.5663381	1.73E-04	173204	1902	RNA binding protein, fox-1 homolog 2	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0021942-&&-radial glia guided migration of Purkinje cell-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0010724-&&-regulation of definitive erythrocyte differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0008380-&&-RNA splicing-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBFOX2				RBFOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBFOX2	0.475400119	0.40527425	0.1203277	65	4	0.00932737	FALSE	11.05405405	RBFOX2	RBFOX2	155.5714286	11.43215566	0	64	0	0.75542251	FALSE	1	RBFOX2	270224	Infinity	0.04641116
791075	taxon:9606	2.39766819	775.2537468	1.10E-04	170128	1902	ATPase family, AAA domain containing 3A	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:ATAD3A	ATAD3A	TRUE		ATAD3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATAD3A	0.487982963	0.41707189	0.10019841	64	4	0.014453464	FALSE	7.41509434	ATAD3A	ATAD3A	236	8.022938738	0	64	0	0.7670553	FALSE	0	ATAD3A	327670	Infinity	0.06245451
787216	taxon:9606	2.52355444	292.3170748	2.16E-04	179849	1902	myelin basic protein	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007417-&&-central nervous system development-%%-GO:0061024-&&-membrane organization-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006955-&&-immune response-%%-GO:0008366-&&-axon ensheathment-%%-GO:0042552-&&-myelination-%%-GO:0009636-&&-response to toxic substance|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005634-&&-nucleus-%%-GO:0033269-&&-internode region of axon-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0019911-&&-structural constituent of myelin sheath-%%-GO:0005515-&&-protein binding	G:9606:MBP				MBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBP	0.454390935	0.39626647	0.06150794	64	4	0.005334216	FALSE	5.026315789	MBP	MBP	105.703125	5.16979837	0	64	0	0.74607426	FALSE	0	MBP	262032	Infinity	0.03538003
791526	taxon:9606	2.44052308	292.6318727	6.26E-05	168249	1902	transducin beta like 1 X-linked receptor 1	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0002021-&&-response to dietary excess-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060613-&&-fat pad development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0016575-&&-histone deacetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090207-&&-regulation of triglyceride metabolic process-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030814-&&-regulation of cAMP metabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:TBL1XR1	TBL1XR1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	TBL1XR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBL1XR1	0.484592145	0.40974822	0.18700397	64	4	0.01311977	FALSE	12.81818182	TBL1XR1	TBL1XR1	200.375	13.43910211	0	64	0	0.75991282	FALSE	0	TBL1XR1	164804	Infinity	0.05651886
791557	taxon:9606	2.76098944	75.17025805	1.29E-04	168048	1902	tectonic family member 1	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0001841-&&-neural tube formation-%%-GO:0021523-&&-somatic motor neuron differentiation-%%-GO:1904491-&&-protein localization to ciliary transition zone-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0021956-&&-central nervous system interneuron axonogenesis-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0021537-&&-telencephalon development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane-%%-GO:0036038-&&-MKS complex	G:9606:TCTN1				TCTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCTN1	0.388565891	0.362189	0.05208333	64	4	0.002527441	FALSE	4.375	TCTN1	TCTN1	51.734375	4.565217391	0	64	0	0.70650176	FALSE	0	TCTN1	132280	Infinity	0.03388158
791804	taxon:9606	2.48715929	157.0654475	3.01E-04	166785	1902	synoviolin 1	gene	biological_process-&-1&-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0036503-&&-ERAD pathway-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0000836-&&-Hrd1p ubiquitin ligase complex-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0000839-&&-Hrd1p ubiquitin ligase ERAD-L complex-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0051117-&&-ATPase binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway	G:9606:SYVN1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SYVN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYVN1	0.456070515	0.40206512	0.13167636	64	4	0.005153697	FALSE	12.28571429	SYVN1	SYVN1	112.1129032	12.64705882	0	63	0	0.75214012	FALSE	1	SYVN1	320710	Infinity	0.03492863
787709	taxon:9606	2.43170002	450.1893958	3.76E-04	178905	1902	phospholipid scramblase 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006915-&&-apoptotic process-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0006659-&&-phosphatidylserine biosynthetic process-%%-GO:0006953-&&-acute-phase response-%%-GO:0033003-&&-regulation of mast cell activation-%%-GO:0051607-&&-defense response to virus-%%-GO:0060368-&&-regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000373-&&-positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0030168-&&-platelet activation-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0017121-&&-phospholipid scrambling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0017128-&&-phospholipid scramblase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0042609-&&-CD4 receptor binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:PLSCR1				PLSCR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLSCR1	0.461981567	0.41123494	0.06944444	64	4	0.00485755	FALSE	4.545454545	PLSCR1	PLSCR1	116.671875	4.791113124	0	64	0	0.76138333	FALSE	0	PLSCR1	406430	Infinity	0.03275629
787772	taxon:9606	2.44493461	329.4077841	9.88E-05	178807	1902	protein phosphatase, Mg2+/Mn2+ dependent 1B	gene	biological_process-&-1&-GO:0006499-&&-N-terminal protein myristoylation-%%-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0050687-&&-negative regulation of defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:PPM1B			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PPM1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPM1B	0.484445787	0.40900889	0.0952381	64	4	0.012901138	FALSE	7.352941176	PPM1B	PPM1B	198.84375	7.55953659	0	64	0	0.75917756	FALSE	0	PPM1B	235924	Infinity	0.05698556
792021	taxon:9606	2.42114385	319.2219841	1.33E-04	182720	1902	Bloom syndrome RecQ like helicase	gene	biological_process-&-1&-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0048478-&&-replication fork protection-%%-GO:0006260-&&-DNA replication-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0031297-&&-replication fork processing-%%-GO:0051782-&&-negative regulation of cell division-%%-GO:0072757-&&-cellular response to camptothecin-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0044806-&&-G-quadruplex DNA unwinding-%%-GO:0000732-&&-strand displacement-%%-GO:0010165-&&-response to X-ray-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0006281-&&-DNA repair-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0090656-&&-t-circle formation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0006310-&&-DNA recombination-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005657-&&-replication fork-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0009378-&&-four-way junction helicase activity-%%-GO:0043140-&&-ATP-dependent 3'-5' DNA helicase activity-%%-GO:0061821-&&-telomeric D-loop binding-%%-GO:0000403-&&-Y-form DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0000405-&&-bubble DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0061749-&&-forked DNA-dependent helicase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0036310-&&-annealing helicase activity-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004386-&&-helicase activity-%%-GO:0051880-&&-G-quadruplex DNA binding	G:9606:BLM			KEGG-&-1&-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway	BLM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLM	0.484738592	0.41302792	0.17239556	64	4	0.010558249	FALSE	13.6122449	BLM	BLM	176.5322581	14.03792408	0	63	0	0.76314269	FALSE	1	BLM	215684	Infinity	0.04818455
792443	taxon:9606	2.38159761	339.8550053	8.92E-05	182008	1902	CTP synthase 1	gene	biological_process-&-1&-GO:0044210-&&-'de novo' CTP biosynthetic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0042098-&&-T cell proliferation-%%-GO:0006241-&&-CTP biosynthetic process-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0006541-&&-glutamine metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003883-&&-CTP synthase activity-%%-GO:0042802-&&-identical protein binding	G:9606:CTPS1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways	CTPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTPS1	0.489322758	0.41988621	0.13696457	64	4	0.01408952	FALSE	11.16	CTPS1	CTPS1	230.8387097	11.54195686	0	63	0	0.76973373	FALSE	1	CTPS1	212510	Infinity	0.05932913
788379	taxon:9606	2.45107925	369.2391109	1.63E-04	177778	1902	signal sequence receptor subunit 1	gene	biological_process-&-1&-GO:0006613-&&-cotranslational protein targeting to membrane-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SSR1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSR1	0.47667162	0.40798354	0.14434524	64	4	0.010195132	FALSE	9.666666667	SSR1	SSR1	169.59375	9.985051024	0	64	0	0.75815346	FALSE	0	SSR1	266282	Infinity	0.04903485
792634	taxon:9606	2.2754057	240.9747073	1.29E-04	181683	1902	eukaryotic translation elongation factor 1 beta 2	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003746-&&-translation elongation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EEF1B2				EEF1B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1B2	0.497056089	0.43948207	0.2141724	64	4	0.018686488	FALSE	16.2	EEF1B2	EEF1B2	296.5645161	16.61975288	0	63	0	0.78743238	FALSE	1	EEF1B2	278630	Infinity	0.06518625
792652	taxon:9606	2.66409327	126.3617646	2.45E-04	181639	1902	cytochrome P450 family 1 subfamily A member 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0009635-&&-response to herbicide-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0009804-&&-coumarin metabolic process-%%-GO:0070988-&&-demethylation-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043010-&&-camera-type eye development-%%-GO:0002933-&&-lipid hydroxylation-%%-GO:0042904-&&-9-cis-retinoic acid biosynthetic process-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0008283-&&-cell proliferation-%%-GO:0010041-&&-response to iron(III) ion-%%-GO:0097267-&&-omega-hydroxylase P450 pathway-%%-GO:0019341-&&-dibenzo-p-dioxin catabolic process-%%-GO:0006778-&&-porphyrin-containing compound metabolic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0009812-&&-flavonoid metabolic process-%%-GO:0017143-&&-insecticide metabolic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0046677-&&-response to antibiotic-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0042493-&&-response to drug-%%-GO:0032094-&&-response to food-%%-GO:0033189-&&-response to vitamin A-%%-GO:0042359-&&-vitamin D metabolic process-%%-GO:0060137-&&-maternal process involved in parturition-%%-GO:0009611-&&-response to wounding-%%-GO:0035902-&&-response to immobilization stress-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0048565-&&-digestive tract development-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009692-&&-ethylene metabolic process-%%-GO:0007568-&&-aging-%%-GO:0009624-&&-response to nematode|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0070576-&&-vitamin D 24-hydroxylase activity-%%-GO:0101020-&&-estrogen 16-alpha-hydroxylase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0016679-&&-oxidoreductase activity, acting on diphenols and related substances as donors-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0070330-&&-aromatase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0020037-&&-heme binding-%%-GO:0032451-&&-demethylase activity-%%-GO:0016711-&&-flavonoid 3'-monooxygenase activity-%%-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding	G:9606:CYP1A1	CYP1A1	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00830-&&-Retinol metabolism-%%-hsa05204-&&-Chemical carcinogenesis	CYP1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP1A1	0.422216373	0.37536223	0.01785714	64	4	0.002757709	FALSE	1.285714286	CYP1A1	CYP1A1	59.390625	1.35	0	64	0	0.72265112	FALSE	0	CYP1A1	239962	Infinity	0.02769553
788631	taxon:9606	2.46525918	267.0559352	2.17E-04	177281	1902	transcription factor CP2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TFCP2				TFCP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFCP2	0.472181336	0.40563686	0.04865151	64	4	0.006170315	FALSE	6.606060606	TFCP2	TFCP2	123.2419355	6.8125	0	63	0	0.75579014	FALSE	1	TFCP2	280226	Infinity	0.03661194
792799	taxon:9606	2.49866078	303.2123332	1.32E-04	181354	1902	eukaryotic translation initiation factor 4A2	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006413-&&-translational initiation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0016032-&&-viral process-%%-GO:1900260-&&-negative regulation of RNA-directed 5'-3' RNA polymerase activity|cellular_component-&-1&-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF4A2			KEGG-&-1&-hsa03013-&&-RNA transport	EIF4A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4A2	0.469692533	0.40021439	0.08778424	64	4	0.008126719	FALSE	8.261904762	EIF4A2	EIF4A2	126.516129	8.478580363	0	63	0	0.7502232	FALSE	1	EIF4A2	186888	Infinity	0.04009992
793117	taxon:9606	2.45769655	515.1526408	5.92E-05	180697	1902	glutamine--fructose-6-phosphate transaminase 1	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0006048-&&-UDP-N-acetylglucosamine biosynthetic process-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0097367-&&-carbohydrate derivative binding-%%-GO:0004360-&&-glutamine-fructose-6-phosphate transaminase (isomerizing) activity	G:9606:GFPT1	GFPT1	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa04931-&&-Insulin resistance	GFPT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFPT1	0.484299517	0.40688506	0.16319444	64	4	0.012292969	FALSE	9.574074074	GFPT1	GFPT1	181.0625	9.90754842	0	64	0	0.75705058	FALSE	0	GFPT1	151958	Infinity	0.05284953
789067	taxon:9606	2.73814401	132.063648	1.51E-04	159865	1902	keratin associated protein 10-9	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KRTAP10-9				KRTAP10-9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-9	0.393426539	0.36521089	0.18297197	64	4	0.001585337	FALSE	9.833333333	KRTAP10-9	KRTAP10-9	56.17741935	10.32712215	0	63	0	0.71030933	FALSE	1	KRTAP10-9	290758	Infinity	0.03337933
789073	taxon:9606	2.73814401	132.063648	1.51E-04	159863	1902	keratin associated protein 10-11	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KRTAP10-11				KRTAP10-11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-11	0.393426539	0.36521089	0.18297197	64	4	0.001585337	FALSE	9.833333333	KRTAP10-11	KRTAP10-11	56.17741935	10.32712215	0	63	0	0.71030933	FALSE	1	KRTAP10-11	290758	Infinity	0.03337933
793333	taxon:9606	2.51993068	260.8116176	2.85E-04	180305	1902	major histocompatibility complex, class I, C	gene	biological_process-&-1&-GO:0002480-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0016032-&&-viral process-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0009986-&&-cell surface-%%-GO:0042612-&&-MHC class I protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0042605-&&-peptide antigen binding-%%-GO:0005102-&&-receptor binding	G:9606:HLA-C			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	HLA-C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-C	0.464523603	0.39683631	0.06345849	64	4	0.006929541	FALSE	7.394736842	HLA-C	HLA-C	117.2096774	7.692920193	0	63	0	0.74667822	FALSE	1	HLA-C	306136	Infinity	0.03879094
789336	taxon:9606	2.43327556	407.356823	2.20E-04	175711	1902	RAB11A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0032402-&&-melanosome transport-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:1990182-&&-exosomal secretion-%%-GO:0072594-&&-establishment of protein localization to organelle-%%-GO:0051650-&&-establishment of vesicle localization-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0000910-&&-cytokinesis-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0060627-&&-regulation of vesicle-mediated transport-%%-GO:0051223-&&-regulation of protein transport-%%-GO:0010796-&&-regulation of multivesicular body size-%%-GO:0098887-&&-neurotransmitter receptor transport, endosome to postsynaptic membrane-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0090150-&&-establishment of protein localization to membrane-%%-GO:0031175-&&-neuron projection development-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0072659-&&-protein localization to plasma membrane|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005828-&&-kinetochore microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005771-&&-multivesicular body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0030424-&&-axon-%%-GO:0000922-&&-spindle pole-%%-GO:0032154-&&-cleavage furrow|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0008017-&&-microtubule binding	G:9606:RAB11A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04972-&&-Pancreatic secretion	RAB11A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB11A	0.477238917	0.41096866	0.09677419	64	4	0.007077356	FALSE	9.256410256	RAB11A	RAB11A	143.7903226	9.627663555	0	63	0	0.76112074	FALSE	1	RAB11A	306960	Infinity	0.04037695
789332	taxon:9606	2.43075469	292.8621614	2.09E-04	175712	1902	TNF receptor superfamily member 14	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0031295-&&-T cell costimulation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0006954-&&-inflammatory response-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0002741-&&-positive regulation of cytokine secretion involved in immune response-%%-GO:0046642-&&-negative regulation of alpha-beta T cell proliferation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TNFRSF14			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF14	0.474837182	0.41139487	0.04653622	64	4	0.007497131	FALSE	6.425	TNFRSF14	TNFRSF14	130.1612903	6.624160101	0	63	0	0.76154089	FALSE	1	TNFRSF14	265112	Infinity	0.03653979
789507	taxon:9606	2.37687096	339.5322208	1.50E-04	175309	1902	nucleoporin 93	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090521-&&-glomerular visceral epithelial cell migration-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0072001-&&-renal system development-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0072015-&&-glomerular visceral epithelial cell development-%%-GO:0006998-&&-nuclear envelope organization-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0016925-&&-protein sumoylation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017056-&&-structural constituent of nuclear pore	G:9606:NUP93			KEGG-&-1&-hsa03013-&&-RNA transport	NUP93	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP93	0.48591336	0.4207212	0.09722222	64	4	0.012717698	FALSE	6.063829787	NUP93	NUP93	228.625	6.240383614	0	64	0	0.77052151	FALSE	0	NUP93	340240	Infinity	0.05825421
789791	taxon:9606	2.47455491	345.6377237	3.25E-04	174671	1902	DExD-box helicase 39A	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0031124-&&-mRNA 3'-end processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:DDX39A				DDX39A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX39A	0.473715298	0.40411308	0.06716023	64	4	0.007134356	FALSE	7.27027027	DDX39A	DDX39A	135.9193548	7.514574315	0	63	0	0.75424085	FALSE	1	DDX39A	390666	Infinity	0.04107436
789793	taxon:9606	2.53363794	288.6859194	2.09E-04	174658	1902	perilipin 3	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005811-&&-lipid particle-%%-GO:0010008-&&-endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PLIN3	PLIN3	TRUE		PLIN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLIN3	0.447544643	0.39468938	0.07667901	64	4	0.004749875	FALSE	6.972222222	PLIN3	PLIN3	102.483871	7.174891775	0	63	0	0.74439368	FALSE	1	PLIN3	248774	Infinity	0.03476727
789963	taxon:9606	2.41657476	575.8354461	1.50E-04	174234	1902	Parkinsonism associated deglycase	gene	biological_process-&-1&-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0006508-&&-proteolysis-%%-GO:0036531-&&-glutathione deglycation-%%-GO:2000157-&&-negative regulation of ubiquitin-specific protease activity-%%-GO:0050821-&&-protein stabilization-%%-GO:0036527-&&-peptidyl-arginine deglycation-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0006914-&&-autophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:2000277-&&-positive regulation of oxidative phosphorylation uncoupler activity-%%-GO:0036528-&&-peptidyl-lysine deglycation-%%-GO:1903094-&&-negative regulation of protein K48-linked deubiquitination-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0009438-&&-methylglyoxal metabolic process-%%-GO:1902903-&&-regulation of supramolecular fiber organization-%%-GO:0006517-&&-protein deglycosylation-%%-GO:2000825-&&-positive regulation of androgen receptor activity-%%-GO:0002866-&&-positive regulation of acute inflammatory response to antigenic stimulus-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0036529-&&-protein deglycation, glyoxal removal-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1903073-&&-negative regulation of death-inducing signaling complex assembly-%%-GO:1903122-&&-negative regulation of TRAIL-activated apoptotic signaling pathway-%%-GO:1903181-&&-positive regulation of dopamine biosynthetic process-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0018323-&&-enzyme active site formation via L-cysteine sulfinic acid-%%-GO:1901671-&&-positive regulation of superoxide dismutase activity-%%-GO:0050787-&&-detoxification of mercury ion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0051899-&&-membrane depolarization-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0045560-&&-regulation of TRAIL receptor biosynthetic process-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:1903202-&&-negative regulation of oxidative stress-induced cell death-%%-GO:0036530-&&-protein deglycation, methylglyoxal removal-%%-GO:1901984-&&-negative regulation of protein acetylation-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:1902958-&&-positive regulation of mitochondrial electron transport, NADH to ubiquinone-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0036471-&&-cellular response to glyoxal-%%-GO:0046295-&&-glycolate biosynthetic process-%%-GO:1903200-&&-positive regulation of L-dopa decarboxylase activity-%%-GO:1905259-&&-negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway-%%-GO:1903189-&&-glyoxal metabolic process-%%-GO:1903178-&&-positive regulation of tyrosine 3-monooxygenase activity-%%-GO:0007338-&&-single fertilization-%%-GO:0019249-&&-lactate biosynthetic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1902177-&&-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:1903197-&&-positive regulation of L-dopa biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0036526-&&-peptidyl-cysteine deglycation-%%-GO:0042743-&&-hydrogen peroxide metabolic process-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:1903168-&&-positive regulation of pyrroline-5-carboxylate reductase activity-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:1903208-&&-negative regulation of hydrogen peroxide-induced neuron death-%%-GO:1903384-&&-negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0010273-&&-detoxification of copper ion-%%-GO:0033864-&&-positive regulation of NAD(P)H oxidase activity-%%-GO:2001268-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0044297-&&-cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0016605-&&-PML body-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0044388-&&-small protein activating enzyme binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0044390-&&-ubiquitin-like protein conjugating enzyme binding-%%-GO:0045340-&&-mercury ion binding-%%-GO:0036524-&&-protein deglycase activity-%%-GO:1903136-&&-cuprous ion binding-%%-GO:0016532-&&-superoxide dismutase copper chaperone activity-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0036470-&&-tyrosine 3-monooxygenase activator activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:1903135-&&-cupric ion binding-%%-GO:0019900-&&-kinase binding-%%-GO:0036478-&&-L-dopa decarboxylase activator activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0016684-&&-oxidoreductase activity, acting on peroxide as acceptor-%%-GO:0019955-&&-cytokine binding-%%-GO:0051920-&&-peroxiredoxin activity	G:9606:PARK7			KEGG-&-1&-hsa05012-&&-Parkinson disease	PARK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARK7	0.488428745	0.41380884	0.12956108	64	4	0.009907763	FALSE	11.11538462	PARK7	PARK7	168.5483871	11.78792099	0	63	0	0.76390421	FALSE	1	PARK7	248142	Infinity	0.04586721
790252	taxon:9606	2.35701906	584.6611536	2.39E-04	173509	1902	ubiquitin protein ligase E3 component n-recognin 4	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:UBR4			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	UBR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBR4	0.491873658	0.42426471	0.11160714	64	4	0.010613246	FALSE	8.169811321	UBR4	UBR4	187.421875	8.500345292	0	64	0	0.77383016	FALSE	0	UBR4	365000	Infinity	0.04642205
790546	taxon:9606	2.46809516	275.0098428	1.89E-04	172531	1902	HtrA serine peptidase 2	gene	biological_process-&-1&-GO:0016540-&&-protein autoprocessing-%%-GO:1904924-&&-negative regulation of mitophagy in response to mitochondrial depolarization-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006508-&&-proteolysis-%%-GO:0009635-&&-response to herbicide-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0007628-&&-adult walking behavior-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:2001269-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0030900-&&-forebrain development-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0019742-&&-pentacyclic triterpenoid metabolic process-%%-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0048666-&&-neuron development-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0034605-&&-cellular response to heat-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0000785-&&-chromatin-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0051082-&&-unfolded protein binding	G:9606:HTRA2			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa05012-&&-Parkinson disease-%%-hsa04210-&&-Apoptosis	HTRA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTRA2	0.46627907	0.40517076	0.06885246	63	4	0.006006768	FALSE	6.947368421	HTRA2	HTRA2	120.7704918	7.150046598	0	62	0	0.75531747	FALSE	1	HTRA2	248446	Infinity	0.03615002
791134	taxon:9606	2.48195998	233.9990394	1.78E-04	169935	1902	NSFL1 cofactor	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0031468-&&-nuclear envelope reassembly-%%-GO:0007030-&&-Golgi organization-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005795-&&-Golgi stack-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990730-&&-VCP-NSFL1C complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:NSFL1C			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	NSFL1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSFL1C	0.473575435	0.40290738	0.10701485	63	4	0.008516242	FALSE	8.128205128	NSFL1C	NSFL1C	137.1587302	8.405326892	0	63	0	0.75300667	FALSE	0	NSFL1C	235210	Infinity	0.04205692
791242	taxon:9606	2.45312746	473.4819866	1.39E-04	169551	1902	par-3 family cell polarity regulator	gene	biological_process-&-1&-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0060341-&&-regulation of cellular localization-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0007409-&&-axonogenesis-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0007163-&&-establishment or maintenance of cell polarity|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0033269-&&-internode region of axon-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0012505-&&-endomembrane system-%%-GO:0043234-&&-protein complex-%%-GO:0044295-&&-axonal growth cone-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:PARD3			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05165-&&-Human papillomavirus infection	PARD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARD3	0.476530006	0.4076429	0.11639344	63	4	0.007996728	FALSE	9.666666667	PARD3	PARD3	146.3278689	10.16164108	0	62	0	0.75781209	FALSE	1	PARD3	215170	Infinity	0.04251528
787308	taxon:9606	2.44320151	247.3773094	1.25E-04	179681	1902	karyopherin subunit alpha 3	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0019054-&&-modulation by virus of host process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0075732-&&-viral penetration into host nucleus|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:KPNA3				KPNA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA3	0.47894894	0.40929903	0.09318996	63	4	0.008202064	FALSE	7.047619048	KPNA3	KPNA3	142.6984127	7.23491656	0	63	0	0.75946641	FALSE	0	KPNA3	202196	Infinity	0.04062063
787388	taxon:9606	2.37340476	354.9989011	1.07E-04	179513	1902	myosin VI	gene	biological_process-&-1&-GO:0030048-&&-actin filament-based movement-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006897-&&-endocytosis-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042493-&&-response to drug-%%-GO:0051046-&&-regulation of secretion|cellular_component-&-1&-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031941-&&-filamentous actin-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0001726-&&-ruffle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045177-&&-apical part of cell-%%-GO:0016461-&&-unconventional myosin complex-%%-GO:0032587-&&-ruffle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005902-&&-microvillus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0060001-&&-minus-end directed microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0003774-&&-motor activity-%%-GO:0043531-&&-ADP binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding	G:9606:MYO6				MYO6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO6	0.491271057	0.42133563	0.16666667	63	4	0.010279126	FALSE	12.80392157	MYO6	MYO6	197.0655738	13.36140876	0	62	0	0.77109921	FALSE	1	MYO6	210338	Infinity	0.0499491
787419	taxon:9606	2.49519458	587.2730484	5.68E-05	179464	1902	lamin B receptor	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0016126-&&-sterol biosynthetic process-%%-GO:0006695-&&-cholesterol biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005639-&&-integral component of nuclear inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016627-&&-oxidoreductase activity, acting on the CH-CH group of donors-%%-GO:0070087-&&-chromo shadow domain binding-%%-GO:0050613-&&-delta14-sterol reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005521-&&-lamin binding	G:9606:LBR	LBR	TRUE		LBR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LBR	0.46996777	0.40077035	0.27650273	63	4	0.017878154	FALSE	20.03508772	LBR	LBR	255.704918	20.51054089	0	62	0	0.7508009	FALSE	1	LBR	208454	Infinity	0.07973267
787496	taxon:9606	2.57444462	107.4805949	2.45E-04	179337	1902	membrane metalloendopeptidase	gene	biological_process-&-1&-GO:0002003-&&-angiotensin maturation-%%-GO:0090399-&&-replicative senescence-%%-GO:0001822-&&-kidney development-%%-GO:0006518-&&-peptide metabolic process-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0006508-&&-proteolysis-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071492-&&-cellular response to UV-A-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:0050435-&&-beta-amyloid metabolic process|cellular_component-&-1&-GO:0044306-&&-neuron projection terminus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0016021-&&-integral component of membrane-%%-GO:0045202-&&-synapse-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005903-&&-brush border-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0008238-&&-exopeptidase activity	G:9606:MME			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04614-&&-Renin-angiotensin system-%%-hsa04974-&&-Protein digestion and absorption	MME	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MME	0.446051168	0.38843329	0.03551913	63	4	0.006575193	FALSE	5.75	MME	MME	103.4754098	5.935483871	0	62	0	0.73759256	FALSE	1	MME	321100	Infinity	0.03877336
791674	taxon:9606	2.66472349	188.1532487	1.66E-04	167480	1902	centrosomal protein 70	gene	biological_process-&-1&-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP70				CEP70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP70	0.431763122	0.37527346	0.03825137	63	4	0.00424061	FALSE	4.310344828	CEP70	CEP70	72.16393443	4.464285714	0	62	0	0.72254608	FALSE	1	CEP70	181576	Infinity	0.03393187
791771	taxon:9606	2.56105247	207.3154455	3.43E-05	166950	1902	lysine acetyltransferase 8	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0016573-&&-histone acetylation|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072487-&&-MSL complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0046872-&&-metal ion binding-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)	G:9606:KAT8				KAT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT8	0.463851938	0.39046447	0.30163934	63	4	0.015194082	FALSE	19.59259259	KAT8	KAT8	218.0327869	20.11830508	0	62	0	0.73982459	FALSE	1	KAT8	112542	Infinity	0.07758007
791867	taxon:9606	2.32093903	302.9453105	8.57E-05	182956	1902	ATP citrate lyase	gene	biological_process-&-1&-GO:0006101-&&-citrate metabolic process-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0006085-&&-acetyl-CoA biosynthetic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0009346-&&-citrate lyase complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0048037-&&-cofactor binding-%%-GO:0003878-&&-ATP citrate synthase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ACLY			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways	ACLY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACLY	0.495061728	0.43086009	0.14371585	63	4	0.015062801	FALSE	11.69811321	ACLY	ACLY	258.0163934	12.03612856	0	62	0	0.7798435	FALSE	1	ACLY	219498	Infinity	0.06051041
787907	taxon:9606	2.44997637	519.2826648	7.60E-05	178634	1902	proteasome activator subunit 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0008537-&&-proteasome activator complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0061133-&&-endopeptidase activator activity-%%-GO:0005515-&&-protein binding	G:9606:PSME1			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa04612-&&-Antigen processing and presentation	PSME1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSME1	0.478092399	0.4081672	0.2284153	63	4	0.008968225	FALSE	17	PSME1	PSME1	155.7377049	17.56296959	0	62	0	0.75833727	FALSE	1	PSME1	160536	Infinity	0.04508315
792253	taxon:9606	2.58342524	230.0277307	1.86E-04	165963	1902	membrane magnesium transporter 1	gene	biological_process-&-1&-GO:1903830-&&-magnesium ion transmembrane transport-%%-GO:0015693-&&-magnesium ion transport-%%-GO:0098655-&&-cation transmembrane transport|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0031901-&&-early endosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0072546-&&-ER membrane protein complex|molecular_function-&-1&-GO:0015095-&&-magnesium ion transmembrane transporter activity-%%-GO:0022890-&&-inorganic cation transmembrane transporter activity	G:9606:MMGT1				MMGT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMGT1	0.425916091	0.387083	0.06144393	63	4	0.003808475	FALSE	4.551724138	MMGT1	MMGT1	83.84126984	4.723544974	0	63	0	0.73609579	FALSE	0	MMGT1	203786	Infinity	0.03203806
792515	taxon:9606	2.48022688	509.1621711	6.94E-05	165486	1902	ubiquitin like with PHD and ring finger domains 2	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0090308-&&-regulation of methylation-dependent chromatin silencing-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0008283-&&-cell proliferation-%%-GO:0007049-&&-cell cycle-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UHRF2				UHRF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UHRF2	0.472320377	0.40318892	0.19945355	63	4	0.011800777	FALSE	14.75	UHRF2	UHRF2	200.0819672	15.47311386	0	62	0	0.75329552	FALSE	1	UHRF2	177986	Infinity	0.06095843
788857	taxon:9606	2.42334961	276.4567071	2.20E-04	176747	1902	vav guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0030168-&&-platelet activation-%%-GO:0007165-&&-signal transduction-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0001525-&&-angiogenesis-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008361-&&-regulation of cell size|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:VAV2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04660-&&-T cell receptor signaling pathway	VAV2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAV2	0.470519214	0.41265197	0.07650273	63	4	0.006095483	FALSE	8.552631579	VAV2	VAV2	140.295082	8.796193252	0	62	0	0.76277506	FALSE	1	VAV2	279174	Infinity	0.038796
792962	taxon:9606	2.58169214	148.2599619	1.59E-04	181082	1902	fumarate hydratase	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006108-&&-malate metabolic process-%%-GO:0006106-&&-fumarate metabolic process-%%-GO:0048873-&&-homeostasis of number of cells within a tissue|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0045239-&&-tricarboxylic acid cycle enzyme complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004333-&&-fumarate hydratase activity-%%-GO:0005515-&&-protein binding	G:9606:FH			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04934-&&-Cushing syndrome	FH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FH	0.448922474	0.38734285	0.10240655	63	4	0.004793261	FALSE	6.896551724	FH	FH	96.26984127	7.142857143	0	63	0	0.73638464	FALSE	0	FH	205888	Infinity	0.03622227
788889	taxon:9606	2.53206239	293.3930626	7.15E-05	176665	1902	XPC complex subunit, DNA damage recognition and repair factor	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006281-&&-DNA repair-%%-GO:0042493-&&-response to drug-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0010996-&&-response to auditory stimulus-%%-GO:0006298-&&-mismatch repair-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0010224-&&-response to UV-B-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000111-&&-nucleotide-excision repair factor 2 complex-%%-GO:0071942-&&-XPC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0000404-&&-heteroduplex DNA loop binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000405-&&-bubble DNA binding	G:9606:XPC			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair	XPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPC	0.467093768	0.39493498	0.18196721	63	4	0.011841686	FALSE	14.26	XPC	XPC	195.6557377	14.61508086	0	62	0	0.74465627	FALSE	1	XPC	181252	Infinity	0.06608883
788925	taxon:9606	2.51536159	233.8349556	8.37E-05	176586	1902	serine/threonine kinase 24	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0048679-&&-regulation of axon regeneration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:STK24				STK24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK24	0.465872785	0.39755716	0.13879781	63	4	0.007928298	FALSE	9.139534884	STK24	STK24	133.0163934	9.376133974	0	62	0	0.74743974	FALSE	1	STK24	145250	Infinity	0.04333813
793160	taxon:9606	2.67071057	88.25918318	3.08E-04	180618	1902	G protein subunit alpha i1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051301-&&-cell division-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:1904322-&&-cellular response to forskolin-%%-GO:0043949-&&-regulation of cAMP-mediated signaling-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0050805-&&-negative regulation of synaptic transmission-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0019003-&&-GDP binding-%%-GO:0031821-&&-G-protein coupled serotonin receptor binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNAI1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05030-&&-Cocaine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04540-&&-Gap junction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAI1	0.415436415	0.37443219	0.07103825	63	4	0.00246881	FALSE	6.5	GNAI1	GNAI1	60.7704918	6.842105263	0	62	0	0.72154824	FALSE	1	GNAI1	310754	Infinity	0.0291439
793246	taxon:9606	2.53206239	237.3437192	1.56E-04	180452	1902	inhibitor of DNA binding 2, HLH protein	gene	biological_process-&-1&-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0048541-&&-Peyer's patch development-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0045578-&&-negative regulation of B cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0061030-&&-epithelial cell differentiation involved in mammary gland alveolus development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060612-&&-adipose tissue development-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0061031-&&-endodermal digestive tract morphogenesis-%%-GO:0001656-&&-metanephros development-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0090398-&&-cellular senescence-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0007275-&&-multicellular organism development-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0071931-&&-positive regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048469-&&-cell maturation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0048667-&&-cell morphogenesis involved in neuron differentiation-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0003166-&&-bundle of His development-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0048557-&&-embryonic digestive tract morphogenesis-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0001966-&&-thigmotaxis-%%-GO:0045475-&&-locomotor rhythm-%%-GO:0043353-&&-enucleate erythrocyte differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0043392-&&-negative regulation of DNA binding|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0044325-&&-ion channel binding	G:9606:ID2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	ID2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ID2	0.460654796	0.39493498	0.06393443	63	4	0.006401506	FALSE	6.485714286	ID2	ID2	117.8688525	6.676470588	0	62	0	0.74465627	FALSE	1	ID2	231288	Infinity	0.03969346
789265	taxon:9606	2.37277454	201.397697	4.96E-05	175872	1902	serine and arginine rich splicing factor 9	gene	biological_process-&-1&-GO:0009636-&&-response to toxic substance-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0043279-&&-response to alkaloid-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRSF9			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF9	0.490070272	0.42144754	0.28264209	63	4	0.017292935	FALSE	18.73684211	SRSF9	SRSF9	247	19.22848743	0	63	0	0.77120424	FALSE	0	SRSF9	135252	Infinity	0.06272219
789438	taxon:9606	2.44698283	212.6342993	3.49E-04	175475	1902	SLC9A3 regulator 1	gene	biological_process-&-1&-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:0070293-&&-renal absorption-%%-GO:0030033-&&-microvillus assembly-%%-GO:0030643-&&-cellular phosphate ion homeostasis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0044062-&&-regulation of excretion-%%-GO:0032415-&&-regulation of sodium:proton antiporter activity-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0006461-&&-protein complex assembly-%%-GO:0097291-&&-renal phosphate ion absorption-%%-GO:0032416-&&-negative regulation of sodium:proton antiporter activity-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0003096-&&-renal sodium ion transport-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0008361-&&-regulation of cell size-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0034635-&&-glutathione transport-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0040023-&&-establishment of nucleus localization-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0032782-&&-bile acid secretion|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0031526-&&-brush border membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0012505-&&-endomembrane system-%%-GO:0031528-&&-microvillus membrane-%%-GO:0032426-&&-stereocilium tip-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0097225-&&-sperm midpiece-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0001726-&&-ruffle-%%-GO:0016020-&&-membrane-%%-GO:0005902-&&-microvillus|molecular_function-&-1&-GO:0017081-&&-chloride channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0050780-&&-dopamine receptor binding-%%-GO:0031698-&&-beta-2 adrenergic receptor binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0043621-&&-protein self-association-%%-GO:0019902-&&-phosphatase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0070851-&&-growth factor receptor binding	G:9606:SLC9A3R1			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	SLC9A3R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC9A3R1	0.471764706	0.40866654	0.10601093	63	4	0.007065641	FALSE	8.972222222	SLC9A3R1	SLC9A3R1	139.5737705	9.247004608	0	62	0	0.7588362	FALSE	1	SLC9A3R1	388382	Infinity	0.04022728
789465	taxon:9606	2.50133922	269.3688695	1.97E-04	175410	1902	BCAR1, Cas family scaffolding protein	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0016477-&&-cell migration-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0050851-&&-antigen receptor-mediated signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0008283-&&-cell proliferation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007015-&&-actin filament organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:BCAR1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05163-&&-Human cytomegalovirus infection	BCAR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAR1	0.460654796	0.39978584	0.16026626	63	4	0.006259344	FALSE	11.60465116	BCAR1	BCAR1	132.7460318	11.98360294	0	63	0	0.7497768	FALSE	0	BCAR1	255742	Infinity	0.04241428
789505	taxon:9606	2.40853947	516.7574978	1.22E-04	175312	1902	clathrin interactor 1	gene	biological_process-&-1&-GO:0048268-&&-clathrin coat assembly-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:CLINT1				CLINT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLINT1	0.488577521	0.41518938	0.18032787	63	4	0.010856841	FALSE	13.31372549	CLINT1	CLINT1	195.9672131	13.94747977	0	62	0	0.76524342	FALSE	1	CLINT1	249876	Infinity	0.05264224
789817	taxon:9606	2.45848432	281.7498666	1.89E-04	174589	1902	ubiquitin specific peptidase 19	gene	biological_process-&-1&-GO:1904292-&&-regulation of ERAD pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:1900037-&&-regulation of cellular response to hypoxia-%%-GO:0050821-&&-protein stabilization-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0090068-&&-positive regulation of cell cycle process|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0046872-&&-metal ion binding	G:9606:USP19				USP19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP19	0.47667162	0.40675468	0.06605223	63	4	0.006439629	FALSE	5.184210526	USP19	USP19	125.6031746	5.33373079	0	63	0	0.75691928	FALSE	0	USP19	250396	Infinity	0.03675514
790148	taxon:9606	2.39404443	430.552384	1.99E-04	173767	1902	tripartite motif containing 32	gene	biological_process-&-1&-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0061564-&&-axon development-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:1903886-&&-positive regulation of chemokine (C-C motif) ligand 20 production-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0009411-&&-response to UV-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0051155-&&-positive regulation of striated muscle cell differentiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0045087-&&-innate immune response-%%-GO:0007014-&&-actin ubiquitination-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:1903883-&&-positive regulation of interleukin-17-mediated signaling pathway-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005863-&&-striated muscle myosin thick filament|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017022-&&-myosin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0043621-&&-protein self-association-%%-GO:0030957-&&-Tat protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:TRIM32			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	TRIM32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM32	0.485031751	0.41770319	0.11092896	63	4	0.008890588	FALSE	10.69565217	TRIM32	TRIM32	174.8196721	11.23665087	0	62	0	0.76765926	FALSE	1	TRIM32	309608	Infinity	0.04586635
790327	taxon:9606	2.4495037	242.6429068	1.67E-04	173307	1902	gem nuclear organelle associated protein 5	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006412-&&-translation-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0016020-&&-membrane-%%-GO:0032797-&&-SMN complex-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0034718-&&-SMN-Gemin2 complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030621-&&-U4 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0030622-&&-U4atac snRNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0017069-&&-snRNA binding-%%-GO:0030619-&&-U1 snRNA binding	G:9606:GEMIN5			KEGG-&-1&-hsa03013-&&-RNA transport	GEMIN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GEMIN5	0.482696359	0.40824596	0.15258577	63	4	0.010917971	FALSE	9.555555556	GEMIN5	GEMIN5	179.3968254	9.775974026	0	63	0	0.75841605	FALSE	0	GEMIN5	260476	Infinity	0.05156676
790873	taxon:9606	2.54261856	131.6385722	1.06E-04	170810	1902	exosome component 4	gene	biological_process-&-1&-GO:0045006-&&-DNA deamination-%%-GO:0034475-&&-U4 snRNA 3'-end processing-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0071051-&&-polyadenylation-dependent snoRNA 3'-end processing-%%-GO:0031125-&&-rRNA 3'-end processing-%%-GO:0071028-&&-nuclear mRNA surveillance-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing-%%-GO:0034427-&&-nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'-%%-GO:0016075-&&-rRNA catabolic process-%%-GO:0051607-&&-defense response to virus-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0071044-&&-histone mRNA catabolic process|cellular_component-&-1&-GO:0000177-&&-cytoplasmic exosome (RNase complex)-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000176-&&-nuclear exosome (RNase complex)-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0045111-&&-intermediate filament cytoskeleton|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0017091-&&-AU-rich element binding	G:9606:EXOSC4			KEGG-&-1&-hsa03018-&&-RNA degradation	EXOSC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOSC4	0.459204123	0.39329533	0.10508475	62	4	0.008101663	FALSE	8.838709677	EXOSC4	EXOSC4	127.2666667	9.133333333	0	61	0	0.74289691	FALSE	1	EXOSC4	161138	Infinity	0.04393207
791027	taxon:9606	2.52418465	130.3113131	1.42E-04	170313	1902	BCL6 corepressor	gene	biological_process-&-1&-GO:0000415-&&-negative regulation of histone H3-K36 methylation-%%-GO:0065001-&&-specification of axis polarity-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042476-&&-odontogenesis-%%-GO:0070171-&&-negative regulation of tooth mineralization-%%-GO:0007507-&&-heart development-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060021-&&-palate development|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:BCOR				BCOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCOR	0.464658169	0.39616753	0.0819209	62	4	0.00632788	FALSE	8.451612903	BCOR	BCOR	120.6833333	8.733333333	0	61	0	0.74596922	FALSE	1	BCOR	213936	Infinity	0.04006645
787179	taxon:9606	2.46856783	238.2989338	1.73E-04	179912	1902	MAD2 mitotic arrest deficient-like 1 (yeast)	gene	biological_process-&-1&-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0090267-&&-positive regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:1904667-&&-negative regulation of ubiquitin protein ligase activity-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:MAD2L1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	MAD2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAD2L1	0.467911319	0.40509318	0.07288136	62	4	0.005273278	FALSE	6.032258065	MAD2L1	MAD2L1	115.4	6.316666667	0	61	0	0.7552387	FALSE	1	MAD2L1	230042	Infinity	0.03448001
787203	taxon:9606	2.38380337	303.4030087	1.47E-04	179868	1902	microtubule associated protein 4	gene	biological_process-&-1&-GO:0031175-&&-neuron projection development-%%-GO:0051301-&&-cell division-%%-GO:0051012-&&-microtubule sliding-%%-GO:0051294-&&-establishment of spindle orientation-%%-GO:1902856-&&-negative regulation of non-motile cilium assembly-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005930-&&-axoneme-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043005-&&-neuron projection-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005198-&&-structural molecule activity	G:9606:MAP4				MAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP4	0.489322758	0.41949769	0.09783184	62	4	0.011054972	FALSE	7.645833333	MAP4	MAP4	189.4193548	7.826552196	0	62	0	0.7693661	FALSE	0	MAP4	267538	Infinity	0.04898818
787309	taxon:9606	2.41106034	296.7662117	9.71E-05	179680	1902	karyopherin subunit alpha 4	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0019054-&&-modulation by virus of host process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:KPNA4				KPNA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA4	0.482696359	0.41475528	0.11898466	62	4	0.009628123	FALSE	8.479166667	KPNA4	KPNA4	160.6451613	8.763349084	0	62	0	0.76482328	FALSE	0	KPNA4	188302	Infinity	0.0432496
787318	taxon:9606	2.51378604	66.82808653	2.75E-04	179675	1902	KRAS proto-oncogene, GTPase	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0050900-&&-leukocyte migration-%%-GO:0021897-&&-forebrain astrocyte development-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0001889-&&-liver development-%%-GO:0007565-&&-female pregnancy-%%-GO:0008542-&&-visual learning-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0038002-&&-endocrine signaling-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0035900-&&-response to isolation stress-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0051385-&&-response to mineralocorticoid-%%-GO:0035022-&&-positive regulation of Rac protein signal transduction-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030275-&&-LRR domain binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019002-&&-GMP binding-%%-GO:0003924-&&-GTPase activity	G:9606:KRAS	KRAS	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05218-&&-Melanoma-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	KRAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRAS	0.450056117	0.39780633	0.02273929	62	4	0.003685421	FALSE	3.095238095	KRAS	KRAS	91.87096774	3.25	0	62	0	0.74770233	FALSE	0	KRAS	333022	Infinity	0.0303074
791452	taxon:9606	2.61729951	233.498782	8.46E-05	168587	1902	DET1 and DDB1 associated 1	gene	biological_process-&-1&-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DDA1				DDA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDA1	0.443829552	0.3820732	0.11528292	62	4	0.006322249	FALSE	7.342857143	DDA1	DDA1	99.93548387	7.571428571	0	62	0	0.73045008	FALSE	0	DDA1	118262	Infinity	0.04094445
791628	taxon:9606	2.55616827	295.5811595	1.73E-04	167744	1902	ubiquitin like modifier activating enzyme 5	gene	biological_process-&-1&-GO:0071569-&&-protein ufmylation-%%-GO:1990592-&&-protein K69-linked ufmylation-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0071566-&&-UFM1 activating enzyme activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:UBA5				UBA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA5	0.459994264	0.39121055	0.04463277	62	4	0.005831575	FALSE	5.264705882	UBA5	UBA5	105.2166667	5.424242424	0	61	0	0.74063862	FALSE	1	UBA5	218458	Infinity	0.0373991
787542	taxon:9606	2.35197731	279.2498393	1.29E-04	179216	1902	protein phosphatase 2 regulatory subunit Balpha	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0032502-&&-developmental process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043278-&&-response to morphine-%%-GO:0070262-&&-peptidyl-serine dephosphorylation|cellular_component-&-1&-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0048156-&&-tau protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:PPP2R2A			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R2A	0.489920586	0.42517417	0.16763617	62	4	0.010269809	FALSE	10.95348837	PPP2R2A	PPP2R2A	193.5967742	11.2755884	0	62	0	0.77467045	FALSE	0	PPP2R2A	242558	Infinity	0.04734575
787571	taxon:9606	2.62785568	284.1798844	1.23E-04	179158	1902	NADH:ubiquinone oxidoreductase core subunit V1	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005829-&&-cytosol-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0010181-&&-FMN binding	G:9606:NDUFV1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFV1	0.432578209	0.3805384	0.14648334	62	4	0.004087151	FALSE	4.633333333	NDUFV1	NDUFV1	85.64516129	4.877155172	0	62	0	0.72869072	FALSE	0	NDUFV1	164998	Infinity	0.0361795
787641	taxon:9606	2.43595399	186.1089744	1.47E-04	162651	1902	RPTOR independent companion of MTOR complex 2	gene	biological_process-&-1&-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0009790-&&-embryo development-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0030950-&&-establishment or maintenance of actin cytoskeleton polarity-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0033135-&&-regulation of peptidyl-serine phosphorylation-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0031929-&&-TOR signaling-%%-GO:0042325-&&-regulation of phosphorylation|cellular_component-&-1&-GO:0031932-&&-TORC2 complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0019901-&&-protein kinase binding	G:9606:RICTOR			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	RICTOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RICTOR	0.482551143	0.41051678	0.1300899	62	4	0.010354209	FALSE	9.162790698	RICTOR	RICTOR	163.2258065	9.380952381	0	62	0	0.76067433	FALSE	0	RICTOR	226946	Infinity	0.04590152
787719	taxon:9606	2.50212699	264.6386537	1.03E-04	178881	1902	PMS1 homolog 2, mismatch repair system component	gene	biological_process-&-1&-GO:0042493-&&-response to drug-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0006298-&&-mismatch repair-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032389-&&-MutLalpha complex-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0004519-&&-endonuclease activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032138-&&-single base insertion or deletion binding-%%-GO:0032407-&&-MutSalpha complex binding	G:9606:PMS2			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03460-&&-Fanconi anemia pathway	PMS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMS2	0.470381232	0.39965997	0.08725542	62	4	0.007347309	FALSE	6.177777778	PMS2	PMS2	134.8225807	6.331252081	0	62	0	0.7496455	FALSE	0	PMS2	195924	Infinity	0.04286535
791888	taxon:9606	2.41925319	173.7394505	3.92E-04	182920	1902	G protein-coupled receptor kinase 2	gene	biological_process-&-1&-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0007217-&&-tachykinin receptor signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0033605-&&-positive regulation of catecholamine secretion-%%-GO:0045988-&&-negative regulation of striated muscle contraction-%%-GO:0003108-&&-negative regulation of the force of heart contraction by chemical signal-%%-GO:0002029-&&-desensitization of G-protein coupled receptor protein signaling pathway-%%-GO:0031623-&&-receptor internalization-%%-GO:0019079-&&-viral genome replication|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005929-&&-cilium-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0047696-&&-beta-adrenergic receptor kinase activity-%%-GO:0031755-&&-Edg-2 lysophosphatidic acid receptor binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031694-&&-alpha-2A adrenergic receptor binding	G:9606:GRK2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04740-&&-Olfactory transduction	GRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK2	0.46091954	0.4133507	0.07879429	62	4	0.005559233	FALSE	6.387096774	GRK2	GRK2	126.0967742	6.629004329	0	62	0	0.7634578	FALSE	0	GRK2	408982	Infinity	0.03456284
787819	taxon:9606	2.49866078	407.1185407	1.79E-04	178750	1902	protein kinase N2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043297-&&-apical junction assembly-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010631-&&-epithelial cell migration|cellular_component-&-1&-GO:0043296-&&-apical junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0032154-&&-cleavage furrow-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0030496-&&-midbody-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005524-&&-ATP binding	G:9606:PKN2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05132-&&-Salmonella infection	PKN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKN2	0.463717838	0.40021439	0.05706215	62	4	0.005782623	FALSE	6.342105263	PKN2	PKN2	115.8333333	6.548273904	0	61	0	0.7502232	FALSE	1	PKN2	231932	Infinity	0.03661912
787818	taxon:9606	2.44131086	287.2331506	3.97E-04	178751	1902	protein kinase N1	gene	biological_process-&-1&-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0003014-&&-renal system process-%%-GO:0010631-&&-epithelial cell migration-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0002637-&&-regulation of immunoglobulin production-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048536-&&-spleen development-%%-GO:0035407-&&-histone H3-T11 phosphorylation-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032154-&&-cleavage furrow-%%-GO:0043234-&&-protein complex-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0017049-&&-GTP-Rho binding-%%-GO:0035402-&&-histone kinase activity (H3-T11 specific)	G:9606:PKN1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05132-&&-Salmonella infection	PKN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKN1	0.472877358	0.40961601	0.06892655	62	4	0.00620409	FALSE	7.459459459	PKN1	PKN1	129.9833333	7.675490196	0	61	0	0.75978152	FALSE	1	PKN1	463006	Infinity	0.03697902
787813	taxon:9606	2.37482275	391.6485152	1.81E-04	178752	1902	protein kinase C iota	gene	biological_process-&-1&-GO:0035089-&&-establishment of apical/basal cell polarity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0048194-&&-Golgi vesicle budding-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007015-&&-actin filament organization-%%-GO:0061024-&&-membrane organization-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0016477-&&-cell migration-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0046903-&&-secretion-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0032869-&&-cellular response to insulin stimulus|cellular_component-&-1&-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0031252-&&-cell leading edge-%%-GO:0043234-&&-protein complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005543-&&-phospholipid binding	G:9606:PRKCI			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	PRKCI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCI	0.481103779	0.42108406	0.10735061	62	4	0.007642326	FALSE	7.977272727	PRKCI	PRKCI	158.6451613	8.213091497	0	62	0	0.77086287	FALSE	0	PRKCI	279908	Infinity	0.04037185
787905	taxon:9606	2.49046794	434.5111438	8.24E-05	178638	1902	proteasome 26S subunit, non-ATPase 10	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070682-&&-proteasome regulatory particle assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PSMD10				PSMD10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD10	0.475400119	0.40153097	0.21152829	62	4	0.00844193	FALSE	14.30188679	PSMD10	PSMD10	157.8709677	14.63793232	0	62	0	0.75158868	FALSE	0	PSMD10	172342	Infinity	0.0491561
792211	taxon:9606	2.42839137	185.0244862	2.56E-04	182401	1902	activating transcription factor 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0061394-&&-regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:1903984-&&-positive regulation of TRAIL-activated apoptotic signaling pathway-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:1990622-&&-CHOP-ATF3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ATF3				ATF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF3	0.472459499	0.41179524	0.19830508	62	4	0.007394919	FALSE	13.94594595	ATF3	ATF3	160.55	14.8015873	0	61	0	0.76193477	FALSE	1	ATF3	324900	Infinity	0.0445787
792212	taxon:9606	2.54309122	186.2979461	2.31E-04	182400	1902	activating transcription factor 4	gene	biological_process-&-1&-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0061395-&&-positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:1990737-&&-response to manganese-induced endoplasmic reticulum stress-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0036091-&&-positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0034644-&&-cellular response to UV-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:1990617-&&-CHOP-ATF4 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:1990589-&&-ATF4-CREB1 transcription factor complex-%%-GO:0043005-&&-neuron projection-%%-GO:1990590-&&-ATF1-ATF4 transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:1990037-&&-Lewy body core-%%-GO:0032590-&&-dendrite membrane-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:ATF4	ATF4	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04210-&&-Apoptosis-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF4	0.441144114	0.39322223	0.13107345	62	4	0.004225414	FALSE	8.896551724	ATF4	ATF4	101.0833333	9.428571429	0	61	0	0.74281813	FALSE	1	ATF4	254896	Infinity	0.03507005
792277	taxon:9606	2.49566724	204.0897837	1.43E-04	182304	1902	cadherin 2	gene	biological_process-&-1&-GO:0044331-&&-cell-cell adhesion mediated by cadherin-%%-GO:1902897-&&-regulation of postsynaptic density protein 95 clustering-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0070445-&&-regulation of oligodendrocyte progenitor proliferation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0034332-&&-adherens junction organization-%%-GO:0097118-&&-neuroligin clustering involved in postsynaptic membrane assembly-%%-GO:0010001-&&-glial cell differentiation-%%-GO:0016339-&&-calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0016477-&&-cell migration-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0060563-&&-neuroepithelial cell differentiation-%%-GO:2000809-&&-positive regulation of synaptic vesicle clustering-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0060019-&&-radial glial cell differentiation|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0016342-&&-catenin complex-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0042383-&&-sarcolemma-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005509-&&-calcium ion binding	G:9606:CDH2			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	CDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDH2	0.469555035	0.40069444	0.0840825	62	4	0.007043661	FALSE	6.470588235	CDH2	CDH2	115.4354839	6.666666667	0	62	0	0.75072213	FALSE	0	CDH2	195946	Infinity	0.03635384
788274	taxon:9606	2.36568458	176.2215654	1.93E-04	177966	1902	ribosomal protein S6 kinase A3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007165-&&-signal transduction-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:0043555-&&-regulation of translation in response to stress-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0007417-&&-central nervous system development-%%-GO:0001501-&&-skeletal system development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:RPS6KA3			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04720-&&-Long-term potentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	RPS6KA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA3	0.480815348	0.42271062	0.12542373	62	4	0.011522212	FALSE	11.79069767	RPS6KA3	RPS6KA3	215.85	12.1087108	0	61	0	0.7723859	FALSE	1	RPS6KA3	347674	Infinity	0.05402169
792448	taxon:9606	2.49424925	89.38149842	5.03E-04	182004	1902	cathepsin D	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0006914-&&-autophagy-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005764-&&-lysosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0042470-&&-melanosome-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004190-&&-aspartic-type endopeptidase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:CTSD	CTSD	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome-%%-hsa04915-&&-Estrogen signaling pathway	CTSD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSD	0.450941805	0.40092224	0.06327684	62	4	0.005718166	FALSE	7.08	CTSD	CTSD	115.7666667	7.375	0	61	0	0.75095846	FALSE	1	CTSD	499050	Infinity	0.03660441
788478	taxon:9606	2.47093115	363.7210472	1.16E-04	177568	1902	small ubiquitin-like modifier 3	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0000776-&&-kinetochore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0005515-&&-protein binding	G:9606:SUMO3			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO3	0.479521674	0.40470573	0.08725542	62	4	0.007852434	FALSE	6.581395349	SUMO3	SUMO3	143.4516129	6.785714286	0	62	0	0.75484481	FALSE	0	SUMO3	207380	Infinity	0.04302043
788481	taxon:9606	2.42634315	815.0722753	2.25E-04	177565	1902	snail family transcriptional repressor 1	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0060972-&&-left/right pattern formation-%%-GO:0001707-&&-mesoderm formation-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060806-&&-negative regulation of cell differentiation involved in embryonic placenta development-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0010957-&&-negative regulation of vitamin D biosynthetic process-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0060021-&&-palate development-%%-GO:0060707-&&-trophoblast giant cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019900-&&-kinase binding	G:9606:SNAI1			KEGG-&-1&-hsa04520-&&-Adherens junction	SNAI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAI1	0.479952124	0.41214286	0.20306716	62	4	0.012274614	FALSE	14.76	SNAI1	SNAI1	215.6451613	15.37002993	0	62	0	0.76227614	FALSE	0	SNAI1	437890	Infinity	0.05992001
792629	taxon:9606	2.45911454	427.7892194	1.12E-04	181690	1902	polyhomeotic homolog 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0000792-&&-heterochromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PHC2				PHC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHC2	0.476388476	0.40665044	0.11073446	62	4	0.007766861	FALSE	8.622222222	PHC2	PHC2	154.9333333	8.911434328	0	61	0	0.75681424	FALSE	1	PHC2	209948	Infinity	0.04526593
788552	taxon:9606	2.4376871	254.816415	1.59E-04	177454	1902	SPT6 homolog, histone chaperone	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051028-&&-mRNA transport-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006342-&&-chromatin silencing-%%-GO:0061086-&&-negative regulation of histone H3-K27 methylation-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0070827-&&-chromatin maintenance-%%-GO:0051147-&&-regulation of muscle cell differentiation-%%-GO:0008380-&&-RNA splicing-%%-GO:0045191-&&-regulation of isotype switching-%%-GO:0034728-&&-nucleosome organization-%%-GO:0006397-&&-mRNA processing-%%-GO:0010793-&&-regulation of mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0006338-&&-chromatin remodeling|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000991-&&-transcription factor activity, core RNA polymerase II binding-%%-GO:0031491-&&-nucleosome binding	G:9606:SUPT6H				SUPT6H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT6H	0.482696359	0.41022492	0.12321523	62	4	0.013777181	FALSE	9.511111111	SUPT6H	SUPT6H	223.5322581	9.757575758	0	62	0	0.76038548	FALSE	0	SUPT6H	276204	Infinity	0.06297051
788547	taxon:9606	2.49283126	234.0108143	2.67E-04	177463	1902	sterol regulatory element binding transcription factor 1	gene	biological_process-&-1&-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0045542-&&-positive regulation of cholesterol biosynthetic process-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0019217-&&-regulation of fatty acid metabolic process-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:0003062-&&-regulation of heart rate by chemical signal-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0030324-&&-lung development-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0009749-&&-response to glucose-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0042493-&&-response to drug-%%-GO:0032094-&&-response to food-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006629-&&-lipid metabolic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0033762-&&-response to glucagon-%%-GO:0007568-&&-aging-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0032810-&&-sterol response element binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0032403-&&-protein complex binding	G:9606:SREBF1	SREBF1	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04931-&&-Insulin resistance	SREBF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SREBF1	0.458678868	0.4011503	0.16497175	62	4	0.006146355	FALSE	10.32432432	SREBF1	SREBF1	133.7833333	10.76106655	0	61	0	0.75119479	FALSE	1	SREBF1	308536	Infinity	0.04176556
792646	taxon:9606	2.43264534	336.0625616	4.34E-04	181644	1902	CD44 molecule (Indian blood group)	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0051216-&&-cartilage development-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0070487-&&-monocyte aggregation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1900625-&&-positive regulation of monocyte aggregation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0035692-&&-macrophage migration inhibitory factor receptor complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005540-&&-hyaluronic acid binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0004896-&&-cytokine receptor activity	G:9606:CD44			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05131-&&-Shigellosis	CD44	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD44	0.471903501	0.41107513	0.10734463	62	4	0.006915109	FALSE	9.720930233	CD44	CD44	150.5833333	10.0495124	0	61	0	0.76122578	FALSE	1	CD44	520772	Infinity	0.04237264
788591	taxon:9606	2.55931936	253.4553258	5.58E-05	177386	1902	transducin beta like 1X-linked	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:TBL1X			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	TBL1X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBL1X	0.461184589	0.39072888	0.14463277	62	4	0.010317191	FALSE	11.57142857	TBL1X	TBL1X	158.7666667	11.98034312	0	61	0	0.74011344	FALSE	1	TBL1X	134792	Infinity	0.0567537
792766	taxon:9606	2.6037498	232.9442671	5.50E-05	181409	1902	DNA methyltransferase 3 alpha	gene	biological_process-&-1&-GO:0010942-&&-positive regulation of cell death-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0006306-&&-DNA methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0010288-&&-response to lead ion-%%-GO:0030182-&&-neuron differentiation-%%-GO:0042220-&&-response to cocaine-%%-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090116-&&-C-5 methylation of cytosine-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0042493-&&-response to drug-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0033189-&&-response to vitamin A-%%-GO:0071230-&&-cellular response to amino acid stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0001741-&&-XY body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0000791-&&-euchromatin-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005720-&&-nuclear heterochromatin|molecular_function-&-1&-GO:0003886-&&-DNA (cytosine-5-)-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding	G:9606:DNMT3A	DNMT3A	TRUE	KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05206-&&-MicroRNAs in cancer	DNMT3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT3A	0.450688396	0.38406148	0.25141243	62	4	0.010823165	FALSE	17.38	DNMT3A	DNMT3A	175.45	17.87091658	0	61	0	0.73270837	FALSE	1	DNMT3A	137468	Infinity	0.0689129
788705	taxon:9606	2.3864818	221.6676239	7.70E-05	177148	1902	topoisomerase (DNA) II beta	gene	biological_process-&-1&-GO:0006312-&&-mitotic recombination-%%-GO:0001764-&&-neuron migration-%%-GO:0016925-&&-protein sumoylation-%%-GO:0000819-&&-sister chromatid segregation-%%-GO:0006265-&&-DNA topological change-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0007409-&&-axonogenesis-%%-GO:0044774-&&-mitotic DNA integrity checkpoint-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000792-&&-heterochromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003918-&&-DNA topoisomerase type II (ATP-hydrolyzing) activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:TOP2B			KEGG-&-1&-hsa01524-&&-Platinum drug resistance	TOP2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOP2B	0.491572173	0.41902687	0.20847458	62	4	0.013349439	FALSE	15.78846154	TOP2B	TOP2B	224.6	16.11531885	0	61	0	0.7689197	FALSE	1	TOP2B	175482	Infinity	0.05792709
788817	taxon:9606	2.45706633	140.027076	1.71E-04	176813	1902	ubiquitin conjugating enzyme E2 E2	gene	biological_process-&-1&-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0032020-&&-ISG15-protein conjugation|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042296-&&-ISG15 transferase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2E2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2E2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E2	0.471625992	0.40698942	0.05423729	62	4	0.00580507	FALSE	7.034482759	UBE2E2	UBE2E2	131.1333333	7.285714286	0	61	0	0.75715561	FALSE	1	UBE2E2	257506	Infinity	0.03825592
789018	taxon:9606	2.4376871	328.8069404	1.77E-04	176369	1902	nuclear receptor interacting protein 1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007623-&&-circadian rhythm-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019915-&&-lipid storage-%%-GO:0001543-&&-ovarian follicle rupture-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0035259-&&-glucocorticoid receptor binding	G:9606:NRIP1	NRIP1	TRUE		NRIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRIP1	0.472459499	0.41022492	0.1173982	62	4	0.007024797	FALSE	8.3	NRIP1	NRIP1	148.1774194	8.570666271	0	62	0	0.76038548	FALSE	0	NRIP1	274064	Infinity	0.04174279
789013	taxon:9606	2.50212699	264.6386537	1.03E-04	127230	1902	mismatch repair endonuclease PMS2	gene		G:9606:LOC107984056				LOC107984056	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC107984056	0.470381232	0.39965997	0.08725542	62	4	0.007347309	FALSE	6.177777778	LOC107984056	LOC107984056	134.8225807	6.331252081	0	62	0	0.7496455	FALSE	0	LOC107984056	195924	Infinity	0.04286535
789510	taxon:9606	2.520876	344.7370732	2.33E-04	175305	1902	Rap guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:2000481-&&-positive regulation of cAMP-dependent protein kinase activity-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0021884-&&-forebrain neuron development-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0071321-&&-cellular response to cGMP-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1901888-&&-regulation of cell junction assembly-%%-GO:2000670-&&-positive regulation of dendritic cell apoptotic process-%%-GO:0031547-&&-brain-derived neurotrophic factor receptor signaling pathway-%%-GO:0031175-&&-neuron projection development-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:0048022-&&-negative regulation of melanin biosynthetic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001568-&&-blood vessel development-%%-GO:0001764-&&-neuron migration-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0021591-&&-ventricular system development-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0030033-&&-microvillus assembly-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0090557-&&-establishment of endothelial intestinal barrier|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0005770-&&-late endosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030553-&&-cGMP binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0017034-&&-Rap guanyl-nucleotide exchange factor activity-%%-GO:0031697-&&-beta-1 adrenergic receptor binding-%%-GO:0019992-&&-diacylglycerol binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0070300-&&-phosphatidic acid binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0050699-&&-WW domain binding	G:9606:RAPGEF2			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04530-&&-Tight junction	RAPGEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAPGEF2	0.468047855	0.3966875	0.04283448	62	4	0.009898645	FALSE	3.133333333	RAPGEF2	RAPGEF2	150.3709677	3.218056529	0	62	0	0.74652067	FALSE	0	RAPGEF2	357446	Infinity	0.04984851
789812	taxon:9606	2.44367418	271.0143115	1.13E-04	174603	1902	BCAS2, pre-mRNA processing factor	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005813-&&-centrosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005730-&&-nucleolus-%%-GO:0000974-&&-Prp19 complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BCAS2			KEGG-&-1&-hsa03040-&&-Spliceosome	BCAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAS2	0.485325265	0.40921986	0.20095188	62	4	0.013287162	FALSE	14.4	BCAS2	BCAS2	193.3548387	14.73049947	0	62	0	0.75938764	FALSE	0	BCAS2	221118	Infinity	0.05521925
790223	taxon:9606	2.49346148	110.1329965	2.83E-04	173592	1902	PAS domain containing serine/threonine kinase	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0070092-&&-regulation of glucagon secretion-%%-GO:0043576-&&-regulation of respiratory gaseous exchange-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PASK				PASK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PASK	0.460522538	0.40104891	0.03502825	62	4	0.005349113	FALSE	5.75	PASK	PASK	104.8833333	6	0	61	0	0.75108975	FALSE	1	PASK	288582	Infinity	0.03286178
790653	taxon:9606	2.479124	195.8627959	8.91E-05	171638	1902	PAF1 homolog, Paf1/RNA polymerase II complex component	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0016584-&&-nucleosome positioning-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0031062-&&-positive regulation of histone methylation-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016593-&&-Cdc73/Paf1 complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:PAF1				PAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAF1	0.470933647	0.40336829	0.21092896	61	4	0.01000173	FALSE	13.3902439	PAF1	PAF1	177.5901639	13.79793628	0	61	0	0.75347933	FALSE	0	PAF1	193258	Infinity	0.05380527
790672	taxon:9606	2.51867024	288.6074919	1.35E-04	171534	1902	homeodomain interacting protein kinase 2	gene	biological_process-&-1&-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007628-&&-adult walking behavior-%%-GO:0030578-&&-PML body organization-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030182-&&-neuron differentiation-%%-GO:0060235-&&-lens induction in camera-type eye-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0010842-&&-retina layer formation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0050882-&&-voluntary musculoskeletal movement-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001654-&&-eye development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060059-&&-embryonic retina morphogenesis in camera-type eye-%%-GO:0061072-&&-iris morphogenesis-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0016605-&&-PML body-%%-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046790-&&-virion binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:HIPK2			KEGG-&-1&-hsa04218-&&-Cellular senescence	HIPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIPK2	0.461848546	0.39703491	0.13091759	61	4	0.006929495	FALSE	11.04878049	HIPK2	HIPK2	135.9661017	11.37408329	0	60	0	0.74688829	FALSE	1	HIPK2	185720	Infinity	0.04493992
790826	taxon:9606	2.47943911	188.8446334	1.20E-04	171070	1902	COP9 signalosome subunit 7A	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS7A				COPS7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS7A	0.471764706	0.40331702	0.20655738	61	4	0.009133045	FALSE	13.13513514	COPS7A	COPS7A	153.2131148	13.55135387	0	61	0	0.75342682	FALSE	0	COPS7A	183862	Infinity	0.04671981
790951	taxon:9606	2.34567512	548.0987798	2.90E-04	170627	1902	DnaJ heat shock protein family (Hsp40) member B11	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:DNAJB11			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJB11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB11	0.488131467	0.4263165	0.09672131	61	4	0.009766287	FALSE	7.285714286	DNAJB11	DNAJB11	198.6229508	7.569750391	0	61	0	0.77572081	FALSE	0	DNAJB11	419874	Infinity	0.04835766
791131	taxon:9606	2.59870805	224.8791995	1.15E-04	169944	1902	myosin VC	gene	cellular_component-&-1&-GO:0016459-&&-myosin complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003774-&&-motor activity-%%-GO:0005516-&&-calmodulin binding	G:9606:MYO5C				MYO5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO5C	0.440296459	0.3848066	0.24480874	61	4	0.005512021	FALSE	14.61111111	MYO5C	MYO5C	104.5737705	15.09285714	0	61	0	0.73354866	FALSE	0	MYO5C	142726	Infinity	0.04117408
791340	taxon:9606	2.49157082	159.2756156	2.94E-04	169097	1902	THO complex 2	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0016973-&&-poly(A)+ mRNA export from nucleus-%%-GO:0048666-&&-neuron development-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0048699-&&-generation of neurons|cellular_component-&-1&-GO:0000445-&&-THO complex part of transcription export complex-%%-GO:0000346-&&-transcription export complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000347-&&-THO complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:THOC2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome	THOC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THOC2	0.471903501	0.40135323	0.10983607	61	4	0.00969468	FALSE	7.617647059	THOC2	THOC2	166.7213115	7.854545455	0	61	0	0.75140486	FALSE	0	THOC2	386420	Infinity	0.05193046
787964	taxon:9606	2.48668662	222.2414724	4.05E-04	178493	1902	pterin-4 alpha-carbinolamine dehydratase 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006559-&&-L-phenylalanine catabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008124-&&-4-alpha-hydroxytetrahydrobiopterin dehydratase activity-%%-GO:0004505-&&-phenylalanine 4-monooxygenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding	G:9606:PCBD1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	PCBD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBD1	0.46627907	0.40214154	0.06019871	61	4	0.007521051	FALSE	7.424242424	PCBD1	PCBD1	131.3898305	7.65625	0	60	0	0.7522189	FALSE	1	PCBD1	494946	Infinity	0.04068743
788209	taxon:9606	2.45879943	146.7884931	2.37E-04	178072	1902	radixin	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0032487-&&-regulation of Rap protein signal transduction-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:1903392-&&-negative regulation of adherens junction organization-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0030033-&&-microvillus assembly-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:1902966-&&-positive regulation of protein localization to early endosome-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0008361-&&-regulation of cell size-%%-GO:0032231-&&-regulation of actin filament bundle assembly-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0034111-&&-negative regulation of homotypic cell-cell adhesion-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:1902115-&&-regulation of organelle assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0045176-&&-apical protein localization-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0010737-&&-protein kinase A signaling|cellular_component-&-1&-GO:0032420-&&-stereocilium-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0051286-&&-cell tip-%%-GO:0005902-&&-microvillus-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0030315-&&-T-tubule-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030027-&&-lamellipodium-%%-GO:0001726-&&-ruffle-%%-GO:0043209-&&-myelin sheath-%%-GO:0030175-&&-filopodium-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003779-&&-actin binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:RDX			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	RDX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RDX	0.473995272	0.40670255	0.0989071	61	4	0.006564764	FALSE	7.34375	RDX	RDX	131.2459016	7.594982079	0	61	0	0.75686676	FALSE	0	RDX	295180	Infinity	0.03855325
788509	taxon:9606	2.42634315	192.9737936	1.21E-04	177528	1902	SOS Ras/Rac guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0003209-&&-cardiac atrium morphogenesis-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:1904693-&&-midbrain morphogenesis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0033081-&&-regulation of T cell differentiation in thymus-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0061384-&&-heart trabecula morphogenesis-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:0051057-&&-positive regulation of small GTPase mediated signal transduction-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:2000973-&&-regulation of pro-B cell differentiation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0060021-&&-palate development-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0001942-&&-hair follicle development-%%-GO:0003344-&&-pericardium morphogenesis-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0007296-&&-vitellogenesis-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:SOS1	SOS1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SOS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOS1	0.469830111	0.41214286	0.23670368	61	4	0.006247329	FALSE	17.34146341	SOS1	SOS1	166.559322	17.84487179	0	60	0	0.76227614	FALSE	1	SOS1	194366	Infinity	0.04622325
788548	taxon:9606	2.49015283	183.8933208	3.17E-04	177462	1902	sterol regulatory element binding transcription factor 2	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0010886-&&-positive regulation of cholesterol storage-%%-GO:0090370-&&-negative regulation of cholesterol efflux-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0055098-&&-response to low-density lipoprotein particle-%%-GO:0072368-&&-regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009267-&&-cellular response to starvation-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032937-&&-SREBP-SCAP-Insig complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070888-&&-E-box binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000247-&&-C-8 sterol isomerase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SREBF2	SREBF2	TRUE		SREBF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SREBF2	0.46344987	0.40158178	0.10987726	61	4	0.005770175	FALSE	9.705882353	SREBF2	SREBF2	128.3898305	10.01368524	0	60	0	0.7516412	FALSE	1	SREBF2	339192	Infinity	0.04009921
792851	taxon:9606	2.43390578	185.9471894	3.37E-04	181271	1902	erb-b2 receptor tyrosine kinase 4	gene	biological_process-&-1&-GO:0007595-&&-lactation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007399-&&-nervous system development-%%-GO:0016477-&&-cell migration-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0021551-&&-central nervous system morphogenesis-%%-GO:0021889-&&-olfactory bulb interneuron differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:2000366-&&-positive regulation of STAT protein import into nucleus-%%-GO:0061026-&&-cardiac muscle tissue regeneration-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0007507-&&-heart development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0007165-&&-signal transduction-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0045165-&&-cell fate commitment|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043235-&&-receptor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:ERBB4	ERBB4	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	ERBB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBB4	0.465062337	0.41086225	0.12857978	61	4	0.006344826	FALSE	11.59459459	ERBB4	ERBB4	148.7457627	12.01587302	0	60	0	0.7610157	FALSE	1	ERBB4	447598	Infinity	0.0417543
788823	taxon:9606	2.62265637	26.03226931	1.78E-04	176810	1902	ubiquitin conjugating enzyme E2 H	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2H			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2H	0.434452871	0.3812928	0.0251315	61	4	0.003380678	FALSE	4.875	UBE2H	UBE2H	76.66101695	5.2	0	60	0	0.72955727	FALSE	1	UBE2H	206286	Infinity	0.03221698
788816	taxon:9606	2.54246101	392.600423	8.72E-05	176818	1902	ubiquitin conjugating enzyme E2 B	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0051026-&&-chiasma assembly-%%-GO:0006301-&&-postreplication repair-%%-GO:0007288-&&-sperm axoneme assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0033522-&&-histone H2A ubiquitination-%%-GO:0070076-&&-histone lysine demethylation-%%-GO:0033128-&&-negative regulation of histone phosphorylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0007283-&&-spermatogenesis-%%-GO:0010845-&&-positive regulation of reciprocal meiotic recombination-%%-GO:0043951-&&-negative regulation of cAMP-mediated signaling-%%-GO:0070193-&&-synaptonemal complex organization-%%-GO:0045141-&&-meiotic telomere clustering-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0050821-&&-protein stabilization-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0033503-&&-HULC complex-%%-GO:0001741-&&-XY body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2B			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2B	0.463583815	0.3933197	0.14377557	61	4	0.005969262	FALSE	9.76744186	UBE2B	UBE2B	117.8305085	10.07279691	0	60	0	0.74292317	FALSE	1	UBE2B	154018	Infinity	0.0408083
793080	taxon:9606	2.45296991	259.442844	1.18E-04	180795	1902	general transcription factor IIIC subunit 1	gene	biological_process-&-1&-GO:0009304-&&-tRNA transcription-%%-GO:0042797-&&-tRNA transcription from RNA polymerase III promoter-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0006384-&&-transcription initiation from RNA polymerase III promoter-%%-GO:0042791-&&-5S class rRNA transcription from RNA polymerase III type 1 promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0009303-&&-rRNA transcription|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000127-&&-transcription factor TFIIIC complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001002-&&-RNA polymerase III type 1 promoter sequence-specific DNA binding-%%-GO:0001007-&&-transcription factor activity, RNA polymerase III transcription factor binding-%%-GO:0000995-&&-transcription factor activity, core RNA polymerase III binding-%%-GO:0001003-&&-RNA polymerase III type 2 promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:GTF3C1				GTF3C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF3C1	0.48009578	0.40766909	0.13551913	61	4	0.011542876	FALSE	9.409090909	GTF3C1	GTF3C1	186.5409836	9.665186751	0	61	0	0.75783835	FALSE	0	GTF3C1	216570	Infinity	0.05422997
793275	taxon:9606	2.45643611	315.2165848	1.25E-04	180384	1902	histone cluster 1 H1 family member b	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0050821-&&-protein stabilization-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006325-&&-chromatin organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0071169-&&-establishment of protein localization to chromatin|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:HIST1H1B				HIST1H1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1B	0.475823198	0.40709384	0.16830601	61	4	0.014123198	FALSE	11.55102041	HIST1H1B	HIST1H1B	222.4262295	11.8422619	0	61	0	0.75726065	FALSE	0	HIST1H1B	264360	Infinity	0.06501774
789257	taxon:9606	2.37750118	357.0097137	8.39E-05	175885	1902	eukaryotic translation initiation factor 3 subunit H	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3H			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa03013-&&-RNA transport	EIF3H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3H	0.490070272	0.42060968	0.21693989	61	4	0.01229792	FALSE	12.62	EIF3H	EIF3H	201.5737705	12.91338975	0	61	0	0.77041647	FALSE	0	EIF3H	192802	Infinity	0.05145289
789558	taxon:9606	2.49188593	439.5130107	2.40E-04	175191	1902	RB1 inducible coiled-coil 1	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0007507-&&-heart development-%%-GO:0061709-&&-reticulophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0061723-&&-glycophagy-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0030242-&&-pexophagy-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006914-&&-autophagy-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0001889-&&-liver development-%%-GO:0000422-&&-mitophagy-%%-GO:0046330-&&-positive regulation of JNK cascade|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:1990316-&&-ATG1/ULK1 kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0005515-&&-protein binding	G:9606:RB1CC1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04211-&&-Longevity regulating pathway	RB1CC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RB1CC1	0.471625992	0.40130248	0.04863388	61	4	0.005647639	FALSE	4.212121212	RB1CC1	RB1CC1	116.5409836	4.34375	0	61	0	0.75135234	FALSE	0	RB1CC1	292870	Infinity	0.03639622
789633	taxon:9606	2.47234914	258.4748782	1.11E-04	175026	1902	TRAF family member associated NFKB activator	gene	biological_process-&-1&-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:2000158-&&-positive regulation of ubiquitin-specific protease activity-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0006508-&&-proteolysis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:1903003-&&-positive regulation of protein deubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0035800-&&-deubiquitinase activator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TANK			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	TANK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TANK	0.474556213	0.40447362	0.1320865	61	4	0.007374039	FALSE	10.69767442	TANK	TANK	138.9322034	10.96917632	0	60	0	0.75460848	FALSE	1	TANK	170124	Infinity	0.04192012
789763	taxon:9606	2.41815031	534.3769707	2.15E-04	174740	1902	B-cell receptor-associated protein 31	gene	biological_process-&-1&-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0070973-&&-protein localization to endoplasmic reticulum exit site-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1904154-&&-positive regulation of retrograde protein transport, ER to cytosol-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005811-&&-lipid particle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005784-&&-Sec61 translocon complex-%%-GO:0005829-&&-cytosol-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0097038-&&-perinuclear endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:BCAP31			KEGG-&-1&-hsa05165-&&-Human papillomavirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	BCAP31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAP31	0.474556213	0.41353922	0.10286382	61	4	0.006904307	FALSE	7.926829268	BCAP31	BCAP31	162.9491525	8.284042858	0	60	0	0.76364162	FALSE	1	BCAP31	327878	Infinity	0.0445367
789980	taxon:9606	2.38459115	214.100127	1.36E-04	174197	1902	5'-3' exoribonuclease 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006396-&&-RNA processing-%%-GO:0021766-&&-hippocampus development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000738-&&-DNA catabolic process, exonucleolytic-%%-GO:0006397-&&-mRNA processing-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0030182-&&-neuron differentiation-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0016235-&&-aggresome|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0008409-&&-5'-3' exonuclease activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004518-&&-nuclease activity-%%-GO:0004534-&&-5'-3' exoribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0001147-&&-transcription termination site sequence-specific DNA binding	G:9606:XRN2			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03018-&&-RNA degradation	XRN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRN2	0.489322758	0.4193591	0.1863388	61	4	0.015389373	FALSE	12.29545455	XRN2	XRN2	258.147541	12.63300709	0	61	0	0.76923481	FALSE	0	XRN2	225194	Infinity	0.06649015
789983	taxon:9606	2.40901213	357.8299935	8.95E-05	174185	1902	coatomer protein complex subunit gamma 1	gene	biological_process-&-1&-GO:0051683-&&-establishment of Golgi localization-%%-GO:0072384-&&-organelle transport along microtubule-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:COPG1				COPG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPG1	0.487686227	0.41510791	0.17708942	61	4	0.010779932	FALSE	11.64444444	COPG1	COPG1	207.8474576	11.97781739	0	60	0	0.76516464	FALSE	1	COPG1	203356	Infinity	0.05568878
790098	taxon:9606	2.60154404	158.5926076	1.33E-04	173878	1902	arginine demethylase and lysine hydroxylase	gene	biological_process-&-1&-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0048821-&&-erythrocyte development-%%-GO:0007507-&&-heart development-%%-GO:0070079-&&-histone H4-R3 demethylation-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0070078-&&-histone H3-R2 demethylation-%%-GO:0001822-&&-kidney development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0008380-&&-RNA splicing-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0006397-&&-mRNA processing-%%-GO:0043654-&&-recognition of apoptotic cell-%%-GO:0042116-&&-macrophage activation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0018395-&&-peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0033749-&&-histone demethylase activity (H4-R3 specific)-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0033746-&&-histone demethylase activity (H3-R2 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0004872-&&-receptor activity-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070815-&&-peptidyl-lysine 5-dioxygenase activity-%%-GO:0003723-&&-RNA binding	G:9606:JMJD6				JMJD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JMJD6	0.449929874	0.38438711	0.11338399	61	4	0.009350821	FALSE	9.184210526	JMJD6	JMJD6	134.6779661	9.459534189	0	60	0	0.73307599	FALSE	1	JMJD6	216454	Infinity	0.05328411
790465	taxon:9606	2.3882149	314.7347853	7.14E-05	172780	1902	GRB10 interacting GYF protein 2	gene	biological_process-&-1&-GO:0061157-&&-mRNA destabilization-%%-GO:0021522-&&-spinal cord motor neuron differentiation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007631-&&-feeding behavior-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0016441-&&-posttranscriptional gene silencing-%%-GO:0050881-&&-musculoskeletal movement-%%-GO:0009791-&&-post-embryonic development|cellular_component-&-1&-GO:1990635-&&-proximal dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:GIGYF2				GIGYF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIGYF2	0.489173529	0.41872279	0.13934426	61	4	0.012290192	FALSE	9.29787234	GIGYF2	GIGYF2	209.7213115	9.524596442	0	61	0	0.76863085	FALSE	0	GIGYF2	182890	Infinity	0.05437555
790621	taxon:9606	2.44367418	233.04535	4.55E-05	171733	1902	eukaryotic translation initiation factor 3 subunit L	gene	biological_process-&-1&-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3L				EIF3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3L	0.481826374	0.40921986	0.30056497	60	4	0.015521837	FALSE	18.38	EIF3L	EIF3L	211.8166667	18.82831688	0	60	0	0.75938764	FALSE	0	EIF3L	130700	Infinity	0.06053158
790659	taxon:9606	2.49078305	175.2315894	2.25E-04	171560	1902	GIT ArfGAP 1	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:GIT1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	GIT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIT1	0.462247839	0.40148017	0.07743497	60	4	0.004793951	FALSE	7.275862069	GIT1	GIT1	119.2241379	7.535714286	0	59	0	0.75153616	FALSE	1	GIT1	278494	Infinity	0.03706923
790866	taxon:9606	2.52150622	195.7283643	1.90E-04	170838	1902	toll interacting protein	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0045321-&&-leukocyte activation-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0036010-&&-protein localization to endosome-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007165-&&-signal transduction-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0045323-&&-interleukin-1 receptor complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016604-&&-nuclear body-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0045092-&&-interleukin-18 receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0035325-&&-Toll-like receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032183-&&-SUMO binding-%%-GO:0005515-&&-protein binding-%%-GO:0005150-&&-interleukin-1, Type I receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0019900-&&-kinase binding	G:9606:TOLLIP			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway	TOLLIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOLLIP	0.446796657	0.39658835	0.07743497	60	4	0.0036152	FALSE	7.103448276	TOLLIP	TOLLIP	100.6206897	7.357142857	0	59	0	0.74641563	FALSE	1	TOLLIP	221632	Infinity	0.03346113
791121	taxon:9606	2.39498976	760.8600655	1.28E-04	169963	1902	unc-45 myosin chaperone A	gene	biological_process-&-1&-GO:0007517-&&-muscle organ development-%%-GO:0030154-&&-cell differentiation-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:UNC45A				UNC45A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNC45A	0.487093835	0.41753832	0.10451977	60	4	0.007604251	FALSE	6.9375	UNC45A	UNC45A	168.8166667	7.233259027	0	60	0	0.76750171	FALSE	0	UNC45A	260640	Infinity	0.04429571
791366	taxon:9606	2.50449031	213.7207313	1.16E-04	168963	1902	KIAA1549	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane	G:9606:KIAA1549				KIAA1549	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA1549	0.458547742	0.39928284	0.1814882	60	4	0.007169279	FALSE	12	KIAA1549	KIAA1549	145.2758621	12.36360652	0	59	0	0.74925161	FALSE	1	KIAA1549	193056	Infinity	0.04649764
791607	taxon:9606	2.56420356	274.8658508	9.55E-05	167843	1902	Smad nuclear interacting protein 1	gene	biological_process-&-1&-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNIP1				SNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNIP1	0.454519694	0.38998464	0.12372881	60	4	0.007331633	FALSE	8.024390244	SNIP1	SNIP1	124.15	8.225	0	60	0	0.73929941	FALSE	0	SNIP1	143970	Infinity	0.04478114
792043	taxon:9606	2.48385064	539.5965641	1.86E-04	182695	1902	dystonin	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0048870-&&-cell motility-%%-GO:0030011-&&-maintenance of cell polarity-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0005882-&&-intermediate filament-%%-GO:0030056-&&-hemidesmosome-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0005737-&&-cytoplasm-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031252-&&-cell leading edge-%%-GO:0031673-&&-H zone-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:DST				DST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DST	0.473715298	0.4026007	0.06327684	60	4	0.007128002	FALSE	4.634146341	DST	DST	141.9833333	4.895375973	0	60	0	0.75269156	FALSE	0	DST	271342	Infinity	0.04380276
792047	taxon:9606	2.41578699	346.7553001	1.46E-04	182688	1902	BRCA2, DNA repair associated	gene	biological_process-&-1&-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0010225-&&-response to UV-C-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0008585-&&-female gonad development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:0001556-&&-oocyte maturation-%%-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0000732-&&-strand displacement-%%-GO:0051298-&&-centrosome duplication-%%-GO:0000910-&&-cytokinesis-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0007569-&&-cell aging-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0048478-&&-replication fork protection-%%-GO:0010165-&&-response to X-ray-%%-GO:0030097-&&-hemopoiesis-%%-GO:0007141-&&-male meiosis I-%%-GO:1990426-&&-mitotic recombination-dependent replication fork processing-%%-GO:0007420-&&-brain development-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0033593-&&-BRCA2-MAGE-D1 complex-%%-GO:0000800-&&-lateral element-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0030141-&&-secretory granule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043015-&&-gamma-tubulin binding-%%-GO:0002020-&&-protease binding-%%-GO:0010484-&&-H3 histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0010485-&&-H4 histone acetyltransferase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:BRCA2			KEGG-&-1&-hsa05212-&&-Pancreatic cancer-%%-hsa05224-&&-Breast cancer-%%-hsa03440-&&-Homologous recombination-%%-hsa05200-&&-Pathways in cancer-%%-hsa03460-&&-Fanconi anemia pathway	BRCA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRCA2	0.484153335	0.41394378	0.12542373	60	4	0.008107384	FALSE	8.604651163	BRCA2	BRCA2	162.8	8.91344086	0	60	0	0.7640355	FALSE	0	BRCA2	222564	Infinity	0.04419857
792215	taxon:9606	2.42208918	245.2686644	1.22E-04	182397	1902	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	gene	biological_process-&-1&-GO:0003360-&&-brainstem development-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0021549-&&-cerebellum development-%%-GO:0009116-&&-nucleoside metabolic process-%%-GO:0046654-&&-tetrahydrofolate biosynthetic process-%%-GO:0046452-&&-dihydrofolate metabolic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010035-&&-response to inorganic substance-%%-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004643-&&-phosphoribosylaminoimidazolecarboxamide formyltransferase activity-%%-GO:0003937-&&-IMP cyclohydrolase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:ATIC			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism-%%-hsa01523-&&-Antifolate resistance	ATIC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATIC	0.478234943	0.41286671	0.10284332	60	4	0.008402355	FALSE	8.552631579	ATIC	ATIC	172.6551724	8.868987054	0	59	0	0.76298514	FALSE	1	ATIC	215198	Infinity	0.0474446
788122	taxon:9606	2.46226564	257.6520508	2.44E-04	178207	1902	protein tyrosine phosphatase, receptor type C	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation-%%-GO:0044770-&&-cell cycle phase transition-%%-GO:0001915-&&-negative regulation of T cell mediated cytotoxicity-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0048539-&&-bone marrow development-%%-GO:0042100-&&-B cell proliferation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0050857-&&-positive regulation of antigen receptor-mediated signaling pathway-%%-GO:0048864-&&-stem cell development-%%-GO:0051607-&&-defense response to virus-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0001960-&&-negative regulation of cytokine-mediated signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0030217-&&-T cell differentiation-%%-GO:0006933-&&-negative regulation of cell adhesion involved in substrate-bound cell migration-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:0002378-&&-immunoglobulin biosynthetic process-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:2000473-&&-positive regulation of hematopoietic stem cell migration|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005925-&&-focal adhesion-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRC			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04660-&&-T cell receptor signaling pathway	PTPRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRC	0.463583815	0.40613002	0.14761041	60	4	0.005595286	FALSE	11.64102564	PTPRC	PTPRC	142.5	11.98361814	0	59	0	0.75628906	FALSE	1	PTPRC	320664	Infinity	0.0422644
788115	taxon:9606	2.40192217	248.56935	1.94E-04	178212	1902	protein tyrosine phosphatase, non-receptor type 12	gene	biological_process-&-1&-GO:0042058-&&-regulation of epidermal growth factor receptor signaling pathway-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0042246-&&-tissue regeneration-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005925-&&-focal adhesion-%%-GO:0002102-&&-podosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:PTPN12				PTPN12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN12	0.469417618	0.41633322	0.11412429	60	4	0.005024628	FALSE	8.676470588	PTPN12	PTPN12	144.1333333	8.939393939	0	60	0	0.76634631	FALSE	0	PTPN12	285598	Infinity	0.03842358
792223	taxon:9606	2.62092327	336.1065005	2.12E-04	182385	1902	ATPase Na+/K+ transporting subunit beta 3	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:1903288-&&-positive regulation of potassium ion import-%%-GO:0006810-&&-transport-%%-GO:0010107-&&-potassium ion import-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:1903278-&&-positive regulation of sodium ion export from cell-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0050821-&&-protein stabilization-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086009-&&-membrane repolarization-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0005901-&&-caveola-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0051117-&&-ATPase binding	G:9606:ATP1B3			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04978-&&-Mineral absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04976-&&-Bile secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1B3	0.441265475	0.38154494	0.0960452	60	4	0.006485005	FALSE	5.594594595	ATP1B3	ATP1B3	96.51666667	5.768518519	0	60	0	0.72984612	FALSE	0	ATP1B3	257638	Infinity	0.04027023
788195	taxon:9606	2.42823381	316.6878826	1.95E-04	178097	1902	RB binding protein 6, ubiquitin ligase	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0048568-&&-embryonic organ development-%%-GO:0006397-&&-mRNA processing-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0061053-&&-somite development-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RBBP6				RBBP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP6	0.475541061	0.41182196	0.06666667	60	4	0.007426139	FALSE	5.342857143	RBBP6	RBBP6	144.4	5.501838235	0	60	0	0.76196103	FALSE	0	RBBP6	293264	Infinity	0.04013823
788215	taxon:9606	2.28107767	501.1917023	1.39E-04	145299	1902	TMX2-CTNND1 readthrough (NMD candidate)	gene		G:9606:TMX2-CTNND1				TMX2-CTNND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMX2-CTNND1	0.497672975	0.43838928	0.16575923	60	4	0.010829497	FALSE	12.07692308	TMX2-CTNND1	TMX2-CTNND1	252.7068966	12.70011961	0	59	0	0.78648705	FALSE	1	TMX2-CTNND1	336494	Infinity	0.0557975
792352	taxon:9606	2.44194107	298.7799033	1.23E-04	182173	1902	creatine kinase B	gene	biological_process-&-1&-GO:0021549-&&-cerebellum development-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0021762-&&-substantia nigra development-%%-GO:0016310-&&-phosphorylation-%%-GO:0030644-&&-cellular chloride ion homeostasis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005615-&&-extracellular space-%%-GO:0005739-&&-mitochondrion-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004111-&&-creatine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CKB			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	CKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKB	0.481681682	0.40951029	0.13389831	60	4	0.01070332	FALSE	8.333333333	CKB	CKB	194.2833333	8.605713656	0	60	0	0.75967649	FALSE	0	CKB	245996	Infinity	0.05510165
792446	taxon:9606	2.28107767	501.1917023	1.39E-04	182010	1902	catenin delta 1	gene	biological_process-&-1&-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0007155-&&-cell adhesion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0034332-&&-adherens junction organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0005915-&&-zonula adherens-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding	G:9606:CTNND1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04520-&&-Adherens junction	CTNND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNND1	0.497672975	0.43838928	0.16575923	60	4	0.010829497	FALSE	12.07692308	CTNND1	CTNND1	252.7068966	12.70011961	0	59	0	0.78648705	FALSE	1	CTNND1	336494	Infinity	0.0557975
792459	taxon:9606	2.55002363	203.9203315	8.13E-05	181980	1902	cytochrome c1	gene	biological_process-&-1&-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0033762-&&-response to glucagon|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005750-&&-mitochondrial respiratory chain complex III-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0045153-&&-electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity-%%-GO:0045155-&&-electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0020037-&&-heme binding	G:9606:CYC1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	CYC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYC1	0.450435271	0.39215323	0.20024198	60	4	0.005426444	FALSE	11.71052632	CYC1	CYC1	120.8793103	12.05890302	0	59	0	0.74166273	FALSE	1	CYC1	141114	Infinity	0.04239287
792558	taxon:9606	2.47266425	206.1915419	1.23E-04	181818	1902	runt related transcription factor 2	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002063-&&-chondrocyte development-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0001503-&&-ossification-%%-GO:0002076-&&-osteoblast development-%%-GO:0030217-&&-T cell differentiation-%%-GO:0040036-&&-regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0042487-&&-regulation of odontogenesis of dentin-containing tooth-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0001958-&&-endochondral ossification-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048469-&&-cell maturation-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0002051-&&-osteoblast fate commitment|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:RUNX2	RUNX2	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	RUNX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUNX2	0.4685948	0.40442207	0.18305085	60	4	0.008263313	FALSE	12.65217391	RUNX2	RUNX2	161.6333333	12.9847799	0	60	0	0.75455596	FALSE	0	RUNX2	190642	Infinity	0.0485627
792619	taxon:9606	2.4512368	580.1424666	3.22E-04	181704	1902	enoyl-CoA hydratase 1	gene	biological_process-&-1&-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005777-&&-peroxisome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0016853-&&-isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:ECH1			KEGG-&-1&-hsa04146-&&-Peroxisome	ECH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECH1	0.470519214	0.40795732	0.06327684	60	4	0.005137898	FALSE	3.970588235	ECH1	ECH1	126.2166667	4.222288676	0	60	0	0.7581272	FALSE	0	ECH1	379532	Infinity	0.03651414
788572	taxon:9606	2.52245155	208.0976326	1.32E-04	177412	1902	TATA-box binding protein associated factor 10	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016578-&&-histone deubiquitination-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0051101-&&-regulation of DNA binding-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0000125-&&-PCAF complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:TAF10			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors	TAF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF10	0.462247839	0.39643973	0.15910466	60	4	0.006795261	FALSE	8.235294118	TAF10	TAF10	125.9827586	8.57416911	0	59	0	0.74625807	FALSE	1	TAF10	181642	Infinity	0.04139178
788637	taxon:9606	2.49692768	280.9939035	9.35E-05	177272	1902	ubiquitin conjugating enzyme E2 A	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006301-&&-postreplication repair-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033522-&&-histone H2A ubiquitination-%%-GO:0060135-&&-maternal process involved in female pregnancy|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0033503-&&-HULC complex-%%-GO:0001741-&&-XY body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2A			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2A	0.474977791	0.40049218	0.10889292	60	4	0.007386722	FALSE	9.268292683	UBE2A	UBE2A	140.2758621	9.509065934	0	59	0	0.75051205	FALSE	1	UBE2A	168524	Infinity	0.04415661
788789	taxon:9606	2.40743658	163.9693699	9.99E-05	160508	1902	tubulin beta 2B class IIb	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0001764-&&-neuron migration-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB2B			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB2B	0.482987052	0.41537958	0.14519774	60	4	0.013187436	FALSE	10.63829787	TUBB2B	TUBB2B	214.7666667	10.86956522	0	60	0	0.76542724	FALSE	0	TUBB2B	232620	Infinity	0.0576775
792930	taxon:9606	2.49424925	259.0773486	2.74E-04	181120	1902	Fanconi anemia complementation group A	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0008584-&&-male gonad development-%%-GO:0008585-&&-female gonad development-%%-GO:0006461-&&-protein complex assembly-%%-GO:0045589-&&-regulation of regulatory T cell differentiation-%%-GO:2000348-&&-regulation of CD40 signaling pathway-%%-GO:0007140-&&-male meiosis-%%-GO:0006281-&&-DNA repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FANCA			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCA	0.475682088	0.40092224	0.09195402	60	4	0.007679786	FALSE	7.714285714	FANCA	FANCA	138.6896552	7.950459297	0	59	0	0.75095846	FALSE	1	FANCA	419784	Infinity	0.04377077
792945	taxon:9606	2.48857728	149.8416365	2.19E-05	181101	1902	FAU, ubiquitin like and ribosomal protein S30 fusion	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:FAU			KEGG-&-1&-hsa03010-&&-Ribosome	FAU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAU	0.475964392	0.40183602	0.50225989	60	4	0.0199742	FALSE	30.46551724	FAU	FAU	210.9	31.03684824	0	60	0	0.75190379	FALSE	0	FAU	77762	Infinity	0.06541046
792967	taxon:9606	2.51536159	220.0297755	2.26E-04	181074	1902	FK506 binding protein 1A	gene	biological_process-&-1&-GO:0022417-&&-protein maturation by protein folding-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0042110-&&-T cell activation-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0050776-&&-regulation of immune response-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:0042026-&&-protein refolding-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060315-&&-negative regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051280-&&-negative regulation of release of sequestered calcium ion into cytosol-%%-GO:1902991-&&-regulation of amyloid precursor protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030018-&&-Z disc-%%-GO:0016020-&&-membrane-%%-GO:0014802-&&-terminal cisterna|molecular_function-&-1&-GO:0048185-&&-activin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0005527-&&-macrolide binding	G:9606:FKBP1A				FKBP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP1A	0.453748232	0.39755716	0.1107078	60	4	0.004236546	FALSE	8.096774194	FKBP1A	FKBP1A	106.1896552	8.410694653	0	59	0	0.74743974	FALSE	1	FKBP1A	247588	Infinity	0.03475948
793094	taxon:9606	2.48763195	326.2061308	1.81E-04	180741	1902	GATA binding protein 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0048821-&&-erythrocyte development-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0030222-&&-eosinophil differentiation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008584-&&-male gonad development-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0010725-&&-regulation of primitive erythrocyte differentiation-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0030220-&&-platelet formation-%%-GO:0010724-&&-regulation of definitive erythrocyte differentiation-%%-GO:0071733-&&-transcriptional activation by promoter-enhancer looping-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0030219-&&-megakaryocyte differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007596-&&-blood coagulation-%%-GO:0035854-&&-eosinophil fate commitment-%%-GO:0030221-&&-basophil differentiation-%%-GO:0010559-&&-regulation of glycoprotein biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030502-&&-negative regulation of bone mineralization|cellular_component-&-1&-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding	G:9606:GATA1				GATA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GATA1	0.463986115	0.40198873	0.10621469	60	4	0.006351125	FALSE	7.512820513	GATA1	GATA1	136.8	7.734183945	0	60	0	0.75206134	FALSE	0	GATA1	248034	Infinity	0.04234583
789145	taxon:9606	2.53537104	468.1976263	1.04E-04	176115	1902	ring finger protein 8	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0007286-&&-spermatid development-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0045190-&&-isotype switching-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043486-&&-histone exchange-%%-GO:0070535-&&-histone H2A K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0033522-&&-histone H2A ubiquitination-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:RNF8				RNF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF8	0.46655032	0.39441959	0.10647308	60	4	0.007254262	FALSE	9.444444444	RNF8	RNF8	131.0172414	9.815614877	0	59	0	0.74410483	FALSE	1	RNF8	168992	Infinity	0.04464412
789163	taxon:9606	2.43437845	302.0605808	7.93E-05	176064	1902	ubiquitin specific peptidase 14	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0050920-&&-regulation of chemotaxis-%%-GO:1903070-&&-negative regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000502-&&-proteasome complex-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0008193-&&-tRNA guanylyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP14				USP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP14	0.481103779	0.41078247	0.27118644	60	4	0.009039822	FALSE	18.26530612	USP14	USP14	166.9833333	18.71296698	0	60	0	0.76093693	FALSE	0	USP14	155756	Infinity	0.04689607
793282	taxon:9606	2.5142587	83.90743793	2.53E-05	180377	1902	histone cluster 1 H2B family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BB	0.467638484	0.39773155	0.45875706	60	4	0.016957492	FALSE	28.55555556	HIST1H2BB	HIST1H2BB	238.4	29.09433962	0	60	0	0.74762355	FALSE	0	HIST1H2BB	105346	Infinity	0.07764929
789700	taxon:9606	2.39609264	384.8600835	1.98E-04	174860	1902	hypoxia up-regulated 1	gene	biological_process-&-1&-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1903382-&&-negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0002931-&&-response to ischemia-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1903298-&&-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005925-&&-focal adhesion-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding	G:9606:HYOU1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HYOU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HYOU1	0.486355367	0.41734613	0.10903955	60	4	0.00987344	FALSE	7.307692308	HYOU1	HYOU1	198.0166667	7.555767438	0	60	0	0.76731789	FALSE	0	HYOU1	321218	Infinity	0.05208279
789731	taxon:9606	2.52812352	205.6042921	1.06E-04	174805	1902	mediator complex subunit 16	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:2000273-&&-positive regulation of receptor activity|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED16			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED16	0.457893234	0.39555029	0.27909605	60	4	0.008421862	FALSE	11.24324324	MED16	MED16	168.05	11.71813725	0	60	0	0.74531275	FALSE	0	MED16	240382	Infinity	0.05580649
789986	taxon:9606	2.50764141	243.0391037	1.14E-04	174181	1902	heat shock protein family A (Hsp70) member 4 like	gene	biological_process-&-1&-GO:0006986-&&-response to unfolded protein-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:HSPA4L			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPA4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA4L	0.466414655	0.3987811	0.08870056	60	4	0.006012929	FALSE	6.756756757	HSPA4L	HSPA4L	123.5666667	6.957885305	0	60	0	0.74872643	FALSE	0	HSPA4L	183856	Infinity	0.03994392
790054	taxon:9606	2.53600126	109.6142182	2.38E-04	173993	1902	ZW10 interacting kinetochore protein	gene	biological_process-&-1&-GO:0051649-&&-establishment of localization in cell-%%-GO:0051301-&&-cell division-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000776-&&-kinetochore-%%-GO:0030425-&&-dendrite-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:ZWINT				ZWINT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZWINT	0.43598804	0.39432157	0.05021174	60	4	0.004082792	FALSE	5.333333333	ZWINT	ZWINT	90.06896552	5.6	0	59	0	0.74399979	FALSE	1	ZWINT	243628	Infinity	0.0308237
790411	taxon:9606	2.54372144	445.8048676	2.12E-04	173086	1902	GABA type A receptor associated protein like 1	gene	biological_process-&-1&-GO:0097352-&&-autophagosome maturation-%%-GO:0016236-&&-macroautophagy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005622-&&-intracellular-%%-GO:0044297-&&-cell body-%%-GO:0032590-&&-dendrite membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005874-&&-microtubule-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005776-&&-autophagosome-%%-GO:0032839-&&-dendrite cytoplasm|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0050811-&&-GABA receptor binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:GABARAPL1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	GABARAPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABARAPL1	0.456070515	0.39312481	0.11129944	60	4	0.004192725	FALSE	7.361111111	GABARAPL1	GABARAPL1	95.63333333	7.80451866	0	60	0	0.74271309	FALSE	0	GABARAPL1	261492	Infinity	0.03306247
790834	taxon:9606	2.60501024	283.6031014	1.49E-04	171011	1902	mediator complex subunit 31	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0060173-&&-limb development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0016592-&&-mediator complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED31				MED31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED31	0.441508395	0.38387565	0.06487434	59	4	0.004089424	FALSE	4.3125	MED31	MED31	91.49152542	4.517473118	0	59	0	0.73249829	FALSE	0	MED31	189004	Infinity	0.03642985
790898	taxon:9606	2.42208918	272.0649806	8.84E-05	170742	1902	leucyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006438-&&-valyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity-%%-GO:0006429-&&-leucyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004823-&&-leucine-tRNA ligase activity-%%-GO:0004832-&&-valine-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:LARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	LARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LARS	0.485619134	0.41286671	0.18468732	59	4	0.010844602	FALSE	11.04878049	LARS	LARS	192.1186441	11.35598834	0	59	0	0.76298514	FALSE	0	LARS	196578	Infinity	0.05282338
790947	taxon:9606	2.47487002	277.5278347	1.47E-04	170629	1902	ubiquitin interaction motif containing 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070537-&&-histone H2A K63-linked deubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:UIMC1			KEGG-&-1&-hsa03440-&&-Homologous recombination	UIMC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UIMC1	0.478377572	0.40406162	0.13383986	59	4	0.008727594	FALSE	8.534883721	UIMC1	UIMC1	160.440678	8.743498168	0	59	0	0.75418833	FALSE	0	UIMC1	229904	Infinity	0.04843566
791050	taxon:9606	2.49188593	258.2833714	2.90E-04	170233	1902	BTG3 associated nuclear protein	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0005515-&&-protein binding	G:9606:BANP				BANP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BANP	0.463851938	0.40130248	0.0820802	59	4	0.006695842	FALSE	8.971428571	BANP	BANP	137.0526316	9.249525617	0	58	0	0.75135234	FALSE	1	BANP	399844	Infinity	0.04281733
791239	taxon:9606	2.55585316	293.9321965	9.21E-05	169562	1902	catenin beta like 1	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0016445-&&-somatic diversification of immunoglobulins-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000974-&&-Prp19 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:CTNNBL1			KEGG-&-1&-hsa03040-&&-Spliceosome	CTNNBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNBL1	0.462781304	0.39125878	0.07205514	59	4	0.010894729	FALSE	6.431818182	CTNNBL1	CTNNBL1	161.4736842	6.696844053	0	58	0	0.74069114	FALSE	1	CTNNBL1	184562	Infinity	0.05754136
787141	taxon:9606	2.42429494	346.024901	1.44E-04	179994	1902	DNA ligase 3	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006288-&&-base-excision repair, DNA ligation-%%-GO:0051301-&&-cell division-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0007049-&&-cell cycle-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0090298-&&-negative regulation of mitochondrial DNA replication-%%-GO:0033151-&&-V(D)J recombination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003910-&&-DNA ligase (ATP) activity	G:9606:LIG3			KEGG-&-1&-hsa03410-&&-Base excision repair	LIG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIG3	0.478377572	0.41249106	0.15195792	59	4	0.011727349	FALSE	9.638297872	LIG3	LIG3	222.1016949	10.0063791	0	59	0	0.76261751	FALSE	0	LIG3	292334	Infinity	0.06119723
791274	taxon:9606	2.39404443	366.4457015	1.72E-04	169413	1902	exportin 5	gene	biological_process-&-1&-GO:0035281-&&-pre-miRNA export from nucleus-%%-GO:1900370-&&-positive regulation of RNA interference-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0031047-&&-gene silencing by RNA|cellular_component-&-1&-GO:0042565-&&-RNA nuclear export complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0090631-&&-pre-miRNA transporter activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:XPO5			KEGG-&-1&-hsa03013-&&-RNA transport	XPO5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO5	0.481826374	0.41770319	0.08883694	59	4	0.009008664	FALSE	5.625	XPO5	XPO5	188.1355932	5.82205131	0	59	0	0.76765926	FALSE	0	XPO5	304546	Infinity	0.04941313
787315	taxon:9606	2.40979991	173.7597534	8.58E-05	179678	1902	transportin 1	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0034399-&&-nuclear periphery-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005929-&&-cilium-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:TNPO1				TNPO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNPO1	0.481681682	0.41497221	0.13408521	59	4	0.012019491	FALSE	11.12195122	TNPO1	TNPO1	210.2807018	11.45970523	0	58	0	0.76503335	FALSE	1	TNPO1	188762	Infinity	0.05658426
787368	taxon:9606	2.55585316	163.9844578	1.12E-04	179552	1902	MYB proto-oncogene, transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045624-&&-positive regulation of T-helper cell differentiation-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:1904899-&&-positive regulation of hepatic stellate cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000845-&&-positive regulation of testosterone secretion-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071636-&&-positive regulation of transforming growth factor beta production|cellular_component-&-1&-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001135-&&-transcription factor activity, RNA polymerase II transcription factor recruiting-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:MYB			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	MYB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYB	0.460126219	0.39125878	0.12507306	59	5	0.007535377	FALSE	8.974358974	MYB	MYB	129.6271186	9.210526316	0	59	0	0.74069114	FALSE	0	MYB	171990	Infinity	0.04637055
787359	taxon:9606	2.477706	142.0126613	1.20E-04	163192	1902	argonaute 3, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0035068-&&-micro-ribonucleoprotein complex|molecular_function-&-1&-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:AGO3				AGO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO3	0.471071953	0.40359914	0.09877265	59	4	0.008668976	FALSE	7.083333333	AGO3	AGO3	146.5254237	7.294372294	0	59	0	0.75371567	FALSE	0	AGO3	183850	Infinity	0.0444433
787382	taxon:9606	2.40270994	308.8612468	1.38E-04	179521	1902	myosin light chain 6	gene	biological_process-&-1&-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction|cellular_component-&-1&-GO:0005903-&&-brush border-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016459-&&-myosin complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0016461-&&-unconventional myosin complex|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MYL6			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04530-&&-Tight junction-%%-hsa04921-&&-Oxytocin signaling pathway	MYL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL6	0.487537994	0.41619672	0.11689071	59	4	0.012396282	FALSE	7.645833333	MYL6	MYL6	207.9830509	7.820011501	0	59	0	0.76621501	FALSE	0	MYL6	248158	Infinity	0.05547365
787444	taxon:9606	2.33905782	287.5465942	8.71E-05	179421	1902	MDM4, p53 regulator	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:0045023-&&-G0 to G1 transition-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:MDM4			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer	MDM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDM4	0.488726386	0.42752257	0.17919799	59	4	0.010604028	FALSE	12.60784314	MDM4	MDM4	217.4210526	12.9399796	0	58	0	0.7768237	FALSE	1	MDM4	198964	Infinity	0.05228138
791568	taxon:9606	2.54057035	350.4269503	2.07E-04	167977	1902	coiled-coil domain containing 33	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC33				CCDC33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC33	0.43610658	0.3936124	0.04734074	59	4	0.003124726	FALSE	3.214285714	CCDC33	CCDC33	88.55932203	3.346215781	0	59	0	0.74323828	FALSE	0	CCDC33	236280	Infinity	0.03068614
787513	taxon:9606	2.44729794	253.2861862	6.20E-05	179311	1902	Mov10 RISC complex RNA helicase	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035195-&&-gene silencing by miRNA|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:MOV10				MOV10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOV10	0.479665072	0.40861392	0.2238457	59	4	0.01562029	FALSE	15.31914894	MOV10	MOV10	228.2711864	15.69519473	0	59	0	0.75878368	FALSE	0	MOV10	160242	Infinity	0.06528527
791655	taxon:9606	2.46746494	212.4731509	6.04E-05	167567	1902	chromatin licensing and DNA replication factor 1	gene	biological_process-&-1&-GO:0000076-&&-DNA replication checkpoint-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0033262-&&-regulation of nuclear cell cycle DNA replication-%%-GO:0006260-&&-DNA replication-%%-GO:0030174-&&-regulation of DNA-dependent DNA replication initiation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:CDT1				CDT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDT1	0.475259259	0.40527425	0.17606516	59	4	0.009939999	FALSE	11.72093023	CDT1	CDT1	174.8947368	12.00833333	0	58	0	0.75542251	FALSE	1	CDT1	130558	Infinity	0.05187174
787619	taxon:9606	2.55853159	238.7106808	1.64E-04	179079	1902	NME/NM23 nucleoside diphosphate kinase 1	gene	biological_process-&-1&-GO:0006241-&&-CTP biosynthetic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006228-&&-UTP biosynthetic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0007399-&&-nervous system development-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0006183-&&-GTP biosynthetic process-%%-GO:0006897-&&-endocytosis-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0004550-&&-nucleoside diphosphate kinase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004536-&&-deoxyribonuclease activity-%%-GO:0042802-&&-identical protein binding	G:9606:NME1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME1	0.452085682	0.39084919	0.06829574	59	4	0.005489477	FALSE	6.441176471	NME1	NME1	108.2982456	6.636363636	0	58	0	0.74024474	FALSE	1	NME1	200196	Infinity	0.03890078
787722	taxon:9606	2.4578541	286.8876854	8.22E-05	178875	1902	pinin, desmosome associated protein	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0030057-&&-desmosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0016020-&&-membrane-%%-GO:0035145-&&-exon-exon junction complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005198-&&-structural molecule activity	G:9606:PNN			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	PNN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNN	0.480527262	0.40685897	0.21491228	59	4	0.011358907	FALSE	15.46511628	PNN	PNN	199.1403509	15.89048906	0	58	0	0.75702432	FALSE	1	PNN	170488	Infinity	0.05796369
791849	taxon:9606	2.38726958	197.7333252	4.48E-05	182977	1902	ATP binding cassette subfamily F member 1	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006954-&&-inflammatory response-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity	G:9606:ABCF1				ABCF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCF1	0.482696359	0.4188886	0.23027469	59	4	0.013926462	FALSE	12.31914894	ABCF1	ABCF1	235.4915254	12.606466	0	59	0	0.7687884	FALSE	0	ABCF1	136066	Infinity	0.061119
792234	taxon:9606	2.68961714	240.0524853	6.14E-04	182374	1902	ATPase H+/K+ transporting alpha subunit	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0006810-&&-transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0008900-&&-hydrogen:potassium-exchanging ATPase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:ATP4A			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04971-&&-Gastric acid secretion	ATP4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP4A	0.40433577	0.37180013	0.03007519	59	4	0.002645502	FALSE	4.517241379	ATP4A	ATP4A	64.26315789	4.769005848	0	58	0	0.71839714	FALSE	1	ATP4A	814856	Infinity	0.03281819
788399	taxon:9606	2.47329447	228.9009535	2.10E-04	177737	1902	serine/threonine kinase 4	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0050821-&&-protein stabilization-%%-GO:0046621-&&-negative regulation of organ growth-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060215-&&-primitive hemopoiesis-%%-GO:0001841-&&-neural tube formation-%%-GO:0003157-&&-endocardium development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060800-&&-regulation of cell differentiation involved in embryonic placenta development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060706-&&-cell differentiation involved in embryonic placenta development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0007165-&&-signal transduction-%%-GO:0035329-&&-hippo signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007417-&&-central nervous system development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:STK4			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer	STK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK4	0.465197216	0.40431902	0.11340852	59	4	0.005777366	FALSE	9.166666667	STK4	STK4	129.8070175	9.428571429	0	58	0	0.75445092	FALSE	1	STK4	252962	Infinity	0.03909971
792556	taxon:9606	2.66724437	236.2316646	1.81E-04	181816	1902	RUNX1 translocation partner 1	gene	biological_process-&-1&-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:RUNX1T1	RUNX1T1	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	RUNX1T1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUNX1T1	0.42033543	0.37491878	0.08834586	59	5	0.003732268	FALSE	8.064516129	RUNX1T1	RUNX1T1	85.8245614	8.345238095	0	58	0	0.72212594	FALSE	1	RUNX1T1	208982	Infinity	0.03986573
788506	taxon:9606	2.49440681	252.7841531	1.63E-04	177539	1902	sorting nexin 2	gene	biological_process-&-1&-GO:0072673-&&-lamellipodium morphogenesis-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0016050-&&-vesicle organization-%%-GO:0051259-&&-protein oligomerization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030905-&&-retromer, tubulation complex-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:1990459-&&-transferrin receptor binding-%%-GO:1990460-&&-leptin receptor binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:SNX2			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX2	0.456719818	0.40089692	0.09711779	59	4	0.004710758	FALSE	5.678571429	SNX2	SNX2	122.7894737	5.901851852	0	58	0	0.7509322	FALSE	1	SNX2	221736	Infinity	0.0384535
788606	taxon:9606	2.40964235	253.0113622	8.08E-05	177349	1902	treacle ribosome biogenesis factor 1	gene	biological_process-&-1&-GO:0001501-&&-skeletal system development-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:TCOF1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	TCOF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCOF1	0.48211602	0.41499935	0.15663355	59	4	0.015762683	FALSE	10.40425532	TCOF1	TCOF1	267.559322	10.68282021	0	59	0	0.76505961	FALSE	0	TCOF1	218876	Infinity	0.07189611
788667	taxon:9606	2.44036553	250.503969	1.03E-04	177224	1902	TIA1 cytotoxic granule associated RNA binding protein like 1	gene	biological_process-&-1&-GO:0006952-&&-defense response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0017145-&&-stem cell division-%%-GO:0006915-&&-apoptotic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007281-&&-germ cell development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005764-&&-lysosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:TIAL1				TIAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIAL1	0.479952124	0.40977468	0.14494448	59	4	0.014175523	FALSE	10.02173913	TIAL1	TIAL1	235.6949153	10.30031489	0	59	0	0.75993908	FALSE	0	TIAL1	237534	Infinity	0.06675019
793049	taxon:9606	2.32535056	334.7547261	1.52E-04	180833	1902	gelsolin	gene	biological_process-&-1&-GO:0051014-&&-actin filament severing-%%-GO:0030041-&&-actin filament polymerization-%%-GO:1903906-&&-regulation of plasma membrane raft polarization-%%-GO:0042246-&&-tissue regeneration-%%-GO:1903923-&&-positive regulation of protein processing in phagocytic vesicle-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0051593-&&-response to folic acid-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0060271-&&-cilium assembly-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001269-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:1903689-&&-regulation of wound healing, spreading of epidermal cells-%%-GO:0051693-&&-actin filament capping-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:1902174-&&-positive regulation of keratinocyte apoptotic process-%%-GO:0014891-&&-striated muscle atrophy-%%-GO:0031648-&&-protein destabilization-%%-GO:0051127-&&-positive regulation of actin nucleation-%%-GO:0097017-&&-renal protein absorption-%%-GO:1903909-&&-regulation of receptor clustering-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0007568-&&-aging-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0042989-&&-sequestering of actin monomers-%%-GO:0071801-&&-regulation of podosome assembly-%%-GO:0045010-&&-actin nucleation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903903-&&-regulation of establishment of T cell polarity-%%-GO:0090527-&&-actin filament reorganization|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016528-&&-sarcoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0002102-&&-podosome-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0030027-&&-lamellipodium-%%-GO:0001726-&&-ruffle-%%-GO:0030478-&&-actin cap-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0045159-&&-myosin II binding	G:9606:GSN			KEGG-&-1&-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04810-&&-Regulation of actin cytoskeleton	GSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSN	0.490070272	0.43004269	0.17475161	59	4	0.010674844	FALSE	11.84782609	GSN	GSN	217.0169492	12.28092951	0	59	0	0.77910824	FALSE	0	GSN	281102	Infinity	0.05116725
793074	taxon:9606	2.41673231	181.7794159	1.68E-04	180807	1902	general transcription factor IIF subunit 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005674-&&-transcription factor TFIIF complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0000991-&&-transcription factor activity, core RNA polymerase II binding	G:9606:GTF2F2			KEGG-&-1&-hsa03022-&&-Basal transcription factors	GTF2F2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2F2	0.474556213	0.41378186	0.12844612	59	4	0.005649866	FALSE	8.9375	GTF2F2	GTF2F2	143.5614035	9.256912442	0	58	0	0.76387795	FALSE	1	GTF2F2	249100	Infinity	0.03901922
789104	taxon:9606	2.35812195	320.6574837	1.35E-04	176191	1902	eukaryotic translation initiation factor 2 subunit beta	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0008584-&&-male gonad development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0002176-&&-male germ cell proliferation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005850-&&-eukaryotic translation initiation factor 2 complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:EIF2S2			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2S2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2S2	0.491271057	0.42406628	0.1233197	59	4	0.010692788	FALSE	8.025641026	EIF2S2	EIF2S2	205.0677966	8.286382623	0	59	0	0.77364634	FALSE	0	EIF2S2	265238	Infinity	0.05075096
793310	taxon:9606	2.38947534	327.9445988	1.36E-04	180332	1902	high density lipoprotein binding protein	gene	biological_process-&-1&-GO:0008203-&&-cholesterol metabolic process-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0034364-&&-high-density lipoprotein particle|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:HDLBP				HDLBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDLBP	0.486945962	0.41850191	0.10169492	59	4	0.010310503	FALSE	7	HDLBP	HDLBP	193.6440678	7.199338296	0	59	0	0.76842078	FALSE	0	HDLBP	238632	Infinity	0.05043676
789395	taxon:9606	2.47550024	313.9923914	1.31E-04	175579	1902	mediator complex subunit 14	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED14			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED14	0.465872785	0.40395876	0.27060199	59	4	0.005204656	FALSE	9.918918919	MED14	MED14	136.2542373	10.38366013	0	59	0	0.75408329	FALSE	0	MED14	214874	Infinity	0.04113151
789902	taxon:9606	2.48038443	115.3932237	4.10E-05	174397	1902	influenza virus NS1A binding protein	gene	biological_process-&-1&-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0009615-&&-response to virus-%%-GO:0008380-&&-RNA splicing-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm	G:9606:IVNS1ABP			KEGG-&-1&-hsa05164-&&-Influenza A	IVNS1ABP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IVNS1ABP	0.478520286	0.40316331	0.18295739	59	4	0.013202506	FALSE	14	IVNS1ABP	IVNS1ABP	175.5438597	14.38034448	0	58	0	0.75326926	FALSE	1	IVNS1ABP	93788	Infinity	0.05351439
790169	taxon:9606	2.41862297	361.0820224	2.20E-04	173726	1902	CCR4-NOT transcription complex subunit 1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0035195-&&-gene silencing by miRNA-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0010606-&&-positive regulation of cytoplasmic mRNA processing body assembly-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0030014-&&-CCR4-NOT complex-%%-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0030015-&&-CCR4-NOT core complex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity	G:9606:CNOT1			KEGG-&-1&-hsa03018-&&-RNA degradation	CNOT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNOT1	0.48313253	0.41345841	0.08942139	59	4	0.008003807	FALSE	5.025	CNOT1	CNOT1	168.1694915	5.161387632	0	59	0	0.76356284	FALSE	0	CNOT1	300476	Infinity	0.04592942
790912	taxon:9606	2.44651016	162.6818201	1.77E-04	170713	1902	histone deacetylase 7	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:0090050-&&-positive regulation of cell migration involved in sprouting angiogenesis-%%-GO:0070932-&&-histone H3 deacetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0033613-&&-activating transcription factor binding	G:9606:HDAC7			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC7	0.472459499	0.40874549	0.17792208	58	4	0.007945271	FALSE	13.10526316	HDAC7	HDAC7	169.7321429	13.45945946	0	57	0	0.75891497	FALSE	1	HDAC7	233702	Infinity	0.04852995
791083	taxon:9606	2.34189381	215.1245855	4.82E-05	170113	1902	N-acetyltransferase 10	gene	biological_process-&-1&-GO:0002101-&&-tRNA wobble cytosine modification-%%-GO:0051391-&&-tRNA acetylation-%%-GO:0000154-&&-rRNA modification-%%-GO:1904812-&&-rRNA acetylation involved in maturation of SSU-rRNA-%%-GO:0008150-&&-biological_process-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0030686-&&-90S preribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005697-&&-telomerase holoenzyme complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:1990883-&&-rRNA cytidine N-acetyltransferase activity-%%-GO:0008080-&&-N-acetyltransferase activity-%%-GO:0051392-&&-tRNA N-acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:NAT10			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NAT10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAT10	0.49751861	0.42700484	0.27586207	58	4	0.019216802	FALSE	16.62962963	NAT10	NAT10	313.7068966	17.02604309	0	58	0	0.77635103	FALSE	0	NAT10	138348	Infinity	0.07570147
791385	taxon:9606	2.60532535	254.0211653	9.23E-05	168851	1902	regulation of nuclear pre-mRNA domain containing 1B	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0010564-&&-regulation of cell cycle process-%%-GO:0070940-&&-dephosphorylation of RNA polymerase II C-terminal domain-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0005515-&&-protein binding	G:9606:RPRD1B				RPRD1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPRD1B	0.449173901	0.38382922	0.15245009	58	4	0.005242181	FALSE	6.441176471	RPRD1B	RPRD1B	106.7586207	6.636363636	0	58	0	0.73244577	FALSE	0	RPRD1B	141538	Infinity	0.04240133
787316	taxon:9606	2.41310856	242.0810193	7.14E-05	179673	1902	keratin 1	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0042730-&&-fibrinolysis-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0001867-&&-complement activation, lectin pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0045095-&&-keratin filament-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0004872-&&-receptor activity	G:9606:KRT1				KRT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT1	0.481681682	0.41440324	0.22323049	58	4	0.014484625	FALSE	9.530612245	KRT1	KRT1	234.1896552	9.794103539	0	58	0	0.76448191	FALSE	0	KRT1	192416	Infinity	0.06356472
787360	taxon:9606	2.55002363	167.8873237	6.17E-05	163191	1902	argonaute 4, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0010586-&&-miRNA metabolic process-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0008584-&&-male gonad development-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007140-&&-male meiosis-%%-GO:0007130-&&-synaptonemal complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000932-&&-P-body-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0035068-&&-micro-ribonucleoprotein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:AGO4				AGO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO4	0.450182431	0.39215323	0.09255898	58	4	0.010913919	FALSE	6.555555556	AGO4	AGO4	137.3275862	6.790703199	0	58	0	0.74166273	FALSE	0	AGO4	125970	Infinity	0.04844761
791709	taxon:9606	2.53221995	257.5520208	1.75E-04	167268	1902	kelch repeat and BTB domain containing 7	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KBTBD7				KBTBD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KBTBD7	0.459335624	0.3949104	0.04718693	58	4	0.005533558	FALSE	3.935483871	KBTBD7	KBTBD7	112.0517241	4.066666667	0	58	0	0.74463001	FALSE	0	KBTBD7	205364	Infinity	0.03771697
791720	taxon:9606	2.51898535	269.060083	1.13E-04	167204	1902	RAB1B, member RAS oncogene family	gene	biological_process-&-1&-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0015031-&&-protein transport-%%-GO:0019068-&&-virion assembly-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:1903020-&&-positive regulation of glycoprotein metabolic process-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding	G:9606:RAB1B			KEGG-&-1&-hsa05134-&&-Legionellosis	RAB1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB1B	0.458678868	0.39698524	0.13974592	58	4	0.005636455	FALSE	8.307692308	RAB1B	RAB1B	117.8793103	8.58708204	0	58	0	0.74683578	FALSE	0	RAB1B	167630	Infinity	0.03896267
787626	taxon:9606	2.50307232	107.8700879	2.58E-04	179067	1902	nitric oxide synthase 3	gene	biological_process-&-1&-GO:0001974-&&-blood vessel remodeling-%%-GO:0050880-&&-regulation of blood vessel size-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0014740-&&-negative regulation of muscle hyperplasia-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity-%%-GO:0009408-&&-response to heat-%%-GO:0030324-&&-lung development-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0014806-&&-smooth muscle hyperplasia-%%-GO:0003100-&&-regulation of systemic arterial blood pressure by endothelin-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0003057-&&-regulation of the force of heart contraction by chemical signal-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006527-&&-arginine catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0001525-&&-angiogenesis-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0042311-&&-vasodilation-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0043542-&&-endothelial cell migration|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0046870-&&-cadmium ion binding-%%-GO:0010181-&&-FMN binding-%%-GO:0050661-&&-NADP binding-%%-GO:0034618-&&-arginine binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004517-&&-nitric-oxide synthase activity-%%-GO:0003785-&&-actin monomer binding-%%-GO:0020037-&&-heme binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0034617-&&-tetrahydrobiopterin binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0003958-&&-NADPH-hemoprotein reductase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:NOS3	NOS3	TRUE	KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	NOS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOS3	0.44955157	0.39950903	0.07272727	58	4	0.004242877	FALSE	5.958333333	NOS3	NOS3	109.7142857	6.217391304	0	57	0	0.74948795	FALSE	1	NOS3	255086	Infinity	0.03506857
791813	taxon:9606	2.44020797	244.5031618	9.11E-05	166755	1902	tubulin beta 6 class V	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003674-&&-molecular_function-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBB6			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB6	0.478234943	0.40980114	0.10828796	58	4	0.010995053	FALSE	7.488888889	TUBB6	TUBB6	191.6034483	7.671990172	0	58	0	0.75996534	FALSE	0	TUBB6	216366	Infinity	0.05448001
791899	taxon:9606	2.36836301	333.7984744	1.40E-04	182914	1902	adaptor related protein complex 1 beta 1 subunit	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:AP1B1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1B1	0.487537994	0.42223257	0.1487013	58	4	0.010361309	FALSE	10.36842105	AP1B1	AP1B1	226.3035714	10.74843185	0	57	0	0.7719395	FALSE	1	AP1B1	266438	Infinity	0.05686102
787815	taxon:9606	2.51662203	80.89846308	2.39E-04	178754	1902	protein kinase C gamma	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007635-&&-chemosensory behavior-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007611-&&-learning or memory-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032095-&&-regulation of response to food-%%-GO:0032425-&&-positive regulation of mismatch repair-%%-GO:0060384-&&-innervation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0043278-&&-response to morphine-%%-GO:0048265-&&-response to pain-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030168-&&-platelet activation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0097060-&&-synaptic membrane|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004698-&&-calcium-dependent protein kinase C activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0005524-&&-ATP binding	G:9606:PRKCG			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04510-&&-Focal adhesion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04970-&&-Salivary secretion	PRKCG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCG	0.443829552	0.39735804	0.04350649	58	4	0.003891028	FALSE	5.52173913	PRKCG	PRKCG	103.4642857	5.772727273	0	57	0	0.74722966	FALSE	1	PRKCG	267408	Infinity	0.03403576
787998	taxon:9606	2.42082874	242.7616633	1.84E-04	178435	1902	pyruvate dehydrogenase (lipoamide) beta	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0061732-&&-mitochondrial acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006086-&&-acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0045254-&&-pyruvate dehydrogenase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004739-&&-pyruvate dehydrogenase (acetyl-transferring) activity-%%-GO:0005515-&&-protein binding-%%-GO:0034604-&&-pyruvate dehydrogenase (NAD+) activity-%%-GO:0004738-&&-pyruvate dehydrogenase activity	G:9606:PDHB			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	PDHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDHB	0.48009578	0.41308168	0.09675325	58	4	0.009693753	FALSE	7.324324324	PDHB	PDHB	185.625	7.561133649	0	57	0	0.76319521	FALSE	1	PDHB	281858	Infinity	0.05097206
788010	taxon:9606	2.50338743	185.2158112	8.64E-05	178402	1902	phosphoribosylformylglycinamidine synthase	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004642-&&-phosphoribosylformylglycinamidine synthase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:PFAS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	PFAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFAS	0.468184472	0.39945875	0.11191773	58	4	0.006586103	FALSE	6.411764706	PFAS	PFAS	138.7758621	6.606060606	0	58	0	0.74943543	FALSE	0	PFAS	139796	Infinity	0.04424701
792145	taxon:9606	2.60296203	226.5165981	1.61E-04	182520	1902	actinin alpha 2	gene	biological_process-&-1&-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0055013-&&-cardiac muscle cell development-%%-GO:0030035-&&-microspike assembly-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0045214-&&-sarcomere organization-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0007155-&&-cell adhesion-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2001137-&&-positive regulation of endocytic recycling-%%-GO:0051695-&&-actin filament uncapping-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:2001259-&&-positive regulation of cation channel activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0086097-&&-phospholipase C-activating angiotensin-activated signaling pathway-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0002576-&&-platelet degranulation-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0031143-&&-pseudopodium-%%-GO:0005925-&&-focal adhesion-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0070080-&&-titin Z domain binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0031432-&&-titin binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0042802-&&-identical protein binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0051373-&&-FATZ binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005178-&&-integrin binding-%%-GO:0030274-&&-LIM domain binding-%%-GO:0044325-&&-ion channel binding	G:9606:ACTN2			KEGG-&-1&-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ACTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTN2	0.442849255	0.38417771	0.07402597	58	4	0.004361742	FALSE	6.451612903	ACTN2	ACTN2	89.05357143	6.75010352	0	57	0	0.73283966	FALSE	1	ACTN2	171132	Infinity	0.03524026
788177	taxon:9606	2.45501812	296.9535612	1.09E-04	178121	1902	RAP1A, member of RAS oncogene family	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0030033-&&-microvillus assembly-%%-GO:0097421-&&-liver regeneration-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0015031-&&-protein transport-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:1905451-&&-positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1901888-&&-regulation of cell junction assembly-%%-GO:0097327-&&-response to antineoplastic agent-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0035690-&&-cellular response to drug-%%-GO:2000301-&&-negative regulation of synaptic vesicle exocytosis-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0007165-&&-signal transduction-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0010976-&&-positive regulation of neuron projection development|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032045-&&-guanyl-nucleotide exchange factor complex-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005769-&&-early endosome-%%-GO:0005770-&&-late endosome-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0017016-&&-Ras GTPase binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0017034-&&-Rap guanyl-nucleotide exchange factor activity-%%-GO:0003924-&&-GTPase activity	G:9606:RAP1A			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04530-&&-Tight junction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04972-&&-Pancreatic secretion	RAP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP1A	0.480815348	0.40732897	0.09220779	58	4	0.006772888	FALSE	7.789473684	RAP1A	RAP1A	144.4821429	8.003753754	0	57	0	0.75749698	FALSE	1	RAP1A	182952	Infinity	0.04208477
788328	taxon:9606	2.55144163	357.4903942	2.34E-04	177878	1902	spermidine/spermine N1-acetyltransferase 1	gene	biological_process-&-1&-GO:0032918-&&-spermidine acetylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0006596-&&-polyamine biosynthetic process-%%-GO:0046208-&&-spermine catabolic process-%%-GO:0009447-&&-putrescine catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004145-&&-diamine N-acetyltransferase activity-%%-GO:0019809-&&-spermidine binding-%%-GO:0005515-&&-protein binding	G:9606:SAT1			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04216-&&-Ferroptosis	SAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAT1	0.44955157	0.39193528	0.05454545	58	4	0.004960982	FALSE	5.694444444	SAT1	SAT1	105.2678571	5.871665968	0	57	0	0.7414264	FALSE	1	SAT1	252590	Infinity	0.0370947
792435	taxon:9606	2.44241374	312.3584184	1.15E-04	182030	1902	cleavage stimulation factor subunit 2	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071920-&&-cleavage body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:CSTF2			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CSTF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTF2	0.477238917	0.40943104	0.11615245	58	4	0.007055482	FALSE	6	CSTF2	CSTF2	145.8275862	6.192398778	0	58	0	0.75959771	FALSE	0	CSTF2	191724	Infinity	0.04157694
788395	taxon:9606	2.54639987	259.1456089	1.88E-04	177747	1902	signal transducer and activator of transcription 6	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0002829-&&-negative regulation of type 2 immune response-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035771-&&-interleukin-4-mediated signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0048295-&&-positive regulation of isotype switching to IgE isotypes-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0002296-&&-T-helper 1 cell lineage commitment-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1902170-&&-cellular response to reactive nitrogen species-%%-GO:0060443-&&-mammary gland morphogenesis|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:STAT6			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation	STAT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT6	0.451830986	0.3927113	0.0961039	58	4	0.005671534	FALSE	8.472222222	STAT6	STAT6	122.0535714	8.714285714	0	57	0	0.74226669	FALSE	1	STAT6	232154	Infinity	0.04263619
792693	taxon:9606	2.54892075	182.7575814	2.35E-04	181554	1902	DNA damage inducible transcript 3	gene	biological_process-&-1&-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006983-&&-ER overload response-%%-GO:0032792-&&-negative regulation of CREB transcription factor activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0042594-&&-response to starvation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0001955-&&-blood vessel maturation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0044324-&&-regulation of transcription involved in anterior/posterior axis specification-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:2000016-&&-negative regulation of determination of dorsal identity-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:1990442-&&-intrinsic apoptotic signaling pathway in response to nitrosative stress-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol|cellular_component-&-1&-GO:0005770-&&-late endosome-%%-GO:0005829-&&-cytosol-%%-GO:1990617-&&-CHOP-ATF4 complex-%%-GO:1990622-&&-CHOP-ATF3 complex-%%-GO:0035976-&&-transcription factor AP-1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0036488-&&-CHOP-C/EBP complex-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008140-&&-cAMP response element binding protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:DDIT3			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DDIT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDIT3	0.456330014	0.39232291	0.16363636	58	4	0.005666866	FALSE	8.413793103	DDIT3	DDIT3	119.7321429	8.928571429	0	57	0	0.74184654	FALSE	1	DDIT3	292642	Infinity	0.0419991
788735	taxon:9606	2.3666299	422.7339104	2.02E-04	177065	1902	tuberous sclerosis 2	gene	biological_process-&-1&-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0061024-&&-membrane organization-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0043276-&&-anoikis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0008104-&&-protein localization-%%-GO:0006897-&&-endocytosis-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0001843-&&-neural tube closure-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:1901525-&&-negative regulation of macromitophagy-%%-GO:0016032-&&-viral process-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007507-&&-heart development-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway|cellular_component-&-1&-GO:0033596-&&-TSC1-TSC2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0031267-&&-small GTPase binding	G:9606:TSC2			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa04150-&&-mTOR signaling pathway	TSC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC2	0.482406015	0.42254177	0.12038717	58	4	0.007962798	FALSE	8.268292683	TSC2	TSC2	186.3103448	8.5753003	0	58	0	0.77222835	FALSE	0	TSC2	291498	Infinity	0.04675474
792940	taxon:9606	2.64502915	194.3740042	3.32E-05	181111	1902	bromodomain PHD finger transcription factor	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0007492-&&-endoderm development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0009611-&&-response to wounding-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016589-&&-NURF complex-%%-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:BPTF				BPTF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BPTF	0.446423601	0.37806767	0.33030853	58	4	0.014469069	FALSE	20.60784314	BPTF	BPTF	209.6206897	21.08891752	0	58	0	0.72582848	FALSE	0	BPTF	98984	Infinity	0.09164242
792991	taxon:9606	2.39278399	339.1259107	2.20E-04	181038	1902	flotillin 2	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0050821-&&-protein stabilization-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0034114-&&-regulation of heterotypic cell-cell adhesion-%%-GO:1903905-&&-positive regulation of establishment of T cell polarity-%%-GO:0001765-&&-membrane raft assembly-%%-GO:0044860-&&-protein localization to plasma membrane raft-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0034139-&&-regulation of toll-like receptor 3 signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:1902992-&&-negative regulation of amyloid precursor protein catabolic process-%%-GO:0045661-&&-regulation of myoblast differentiation|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016600-&&-flotillin complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005901-&&-caveola-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0002020-&&-protease binding	G:9606:FLOT2			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	FLOT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLOT2	0.477238917	0.41792322	0.13732607	58	4	0.008097	FALSE	9.487804878	FLOT2	FLOT2	176.2586207	9.825230415	0	58	0	0.76786933	FALSE	0	FLOT2	309178	Infinity	0.04623187
789218	taxon:9606	2.50464787	204.8321169	1.42E-04	175978	1902	basic helix-loop-helix family member e40	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070888-&&-E-box binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043426-&&-MRF binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:BHLHE40			KEGG-&-1&-hsa04710-&&-Circadian rhythm	BHLHE40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BHLHE40	0.461715602	0.39925772	0.10779221	58	4	0.005829498	FALSE	8.529411765	BHLHE40	BHLHE40	131.1071429	8.82666527	0	57	0	0.74922536	FALSE	1	BHLHE40	202142	Infinity	0.0419123
789248	taxon:9606	2.47959666	225.79485	1.55E-04	175898	1902	suppressor of cytokine signaling 1	gene	biological_process-&-1&-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0010534-&&-regulation of activation of JAK2 kinase activity-%%-GO:0050707-&&-regulation of cytokine secretion-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042512-&&-negative regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0040008-&&-regulation of growth-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007259-&&-JAK-STAT cascade|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0019210-&&-kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0019901-&&-protein kinase binding	G:9606:SOCS1	SOCS1	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation	SOCS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS1	0.456070515	0.4032914	0.18935269	58	4	0.005147443	FALSE	11.94594595	SOCS1	SOCS1	138.137931	12.27777778	0	58	0	0.75340056	FALSE	0	SOCS1	244824	Infinity	0.04225166
789288	taxon:9606	2.54813298	236.7664671	7.79E-05	175823	1902	zinc finger RANBP2-type containing 2	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:ZRANB2				ZRANB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZRANB2	0.46344987	0.3924442	0.12467532	58	4	0.007399034	FALSE	8.923076923	ZRANB2	ZRANB2	127.8571429	9.157894737	0	57	0	0.74197784	FALSE	1	ZRANB2	137034	Infinity	0.04478677
789735	taxon:9606	2.66692926	247.7049894	1.94E-04	174798	1902	poly(ADP-ribose) polymerase 2	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0006281-&&-DNA repair-%%-GO:0006273-&&-lagging strand elongation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003910-&&-DNA ligase (ATP) activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:PARP2			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis	PARP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARP2	0.428418803	0.37496308	0.13551119	58	4	0.008653064	FALSE	9.512820513	PARP2	PARP2	147.2931035	9.765413534	0	58	0	0.72217846	FALSE	0	PARP2	352160	Infinity	0.0694458
789898	taxon:9606	2.43264534	132.0853336	1.68E-04	174404	1902	RANBP2-type and C3HC4-type zinc finger containing 1	gene	biological_process-&-1&-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0097039-&&-protein linear polyubiquitination-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0060546-&&-negative regulation of necroptotic process|cellular_component-&-1&-GO:0071797-&&-LUBAC complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RBCK1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	RBCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBCK1	0.472181336	0.41107513	0.15519481	58	4	0.006863069	FALSE	11.72222222	RBCK1	RBCK1	157.625	12.05714286	0	57	0	0.76122578	FALSE	1	RBCK1	237678	Infinity	0.04422175
790143	taxon:9606	2.53017173	299.2026693	1.04E-04	173782	1902	sirtuin 2	gene	biological_process-&-1&-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006476-&&-protein deacetylation-%%-GO:0051301-&&-cell division-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:1900226-&&-negative regulation of NLRP3 inflammasome complex assembly-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0070446-&&-negative regulation of oligodendrocyte progenitor proliferation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:1900425-&&-negative regulation of defense response to bacterium-%%-GO:0006914-&&-autophagy-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0016458-&&-gene silencing-%%-GO:0031641-&&-regulation of myelination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0021762-&&-substantia nigra development-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0071219-&&-cellular response to molecule of bacterial origin-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0045843-&&-negative regulation of striated muscle tissue development-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:1900195-&&-positive regulation of oocyte maturation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000777-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia-%%-GO:0090042-&&-tubulin deacetylation-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0006342-&&-chromatin silencing-%%-GO:0006348-&&-chromatin silencing at telomere-%%-GO:0045836-&&-positive regulation of meiotic nuclear division-%%-GO:0061428-&&-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045087-&&-innate immune response-%%-GO:0051987-&&-positive regulation of attachment of spindle microtubules to kinetochore-%%-GO:0051775-&&-response to redox state-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:1901026-&&-ripoptosome assembly involved in necroptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0061433-&&-cellular response to caloric restriction-%%-GO:0044242-&&-cellular lipid catabolic process-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016575-&&-histone deacetylation-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005874-&&-microtubule-%%-GO:0043209-&&-myelin sheath-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043219-&&-lateral loop-%%-GO:0030496-&&-midbody-%%-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0030426-&&-growth cone-%%-GO:0044224-&&-juxtaparanode region of axon-%%-GO:0043204-&&-perikaryon-%%-GO:0033270-&&-paranode region of axon-%%-GO:0005694-&&-chromosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0097386-&&-glial cell projection-%%-GO:0005814-&&-centriole-%%-GO:0005737-&&-cytoplasm-%%-GO:0033010-&&-paranodal junction-%%-GO:0005829-&&-cytosol-%%-GO:0072687-&&-meiotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046970-&&-NAD-dependent histone deacetylase activity (H4-K16 specific)-%%-GO:0042903-&&-tubulin deacetylase activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0034979-&&-NAD-dependent protein deacetylase activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0070403-&&-NAD+ binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0017136-&&-NAD-dependent histone deacetylase activity	G:9606:SIRT2				SIRT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT2	0.461449942	0.39523009	0.12337662	58	4	0.009064531	FALSE	10.65853659	SIRT2	SIRT2	169.1785714	10.92763158	0	57	0	0.74497138	FALSE	1	SIRT2	182980	Infinity	0.05701522
790274	taxon:9606	2.46636206	290.1634584	2.13E-04	173466	1902	dicer 1, ribonuclease III	gene	biological_process-&-1&-GO:0014040-&&-positive regulation of Schwann cell differentiation-%%-GO:0033168-&&-conversion of ds siRNA to ss siRNA involved in RNA interference-%%-GO:0036404-&&-conversion of ds siRNA to ss siRNA-%%-GO:0030423-&&-targeting of mRNA for destruction involved in RNA interference-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0021675-&&-nerve development-%%-GO:0032290-&&-peripheral nervous system myelin formation-%%-GO:0010626-&&-negative regulation of Schwann cell proliferation-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0030422-&&-production of siRNA involved in RNA interference-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035087-&&-siRNA loading onto RISC involved in RNA interference|cellular_component-&-1&-GO:0033167-&&-ARC complex-%%-GO:0030424-&&-axon-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0030426-&&-growth cone-%%-GO:0030425-&&-dendrite-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0035197-&&-siRNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004525-&&-ribonuclease III activity-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:DICER1	DICER1	TRUE	KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	DICER1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DICER1	0.47010551	0.40545547	0.11103896	58	4	0.008726491	FALSE	9.970588235	DICER1	DICER1	165.4285714	10.37151515	0	57	0	0.75560632	FALSE	1	DICER1	292024	Infinity	0.04891419
790305	taxon:9606	2.55868914	85.0638383	3.95E-05	173368	1902	anti-silencing function 1A histone chaperone	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006281-&&-DNA repair-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031936-&&-negative regulation of chromatin silencing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:ASF1A				ASF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASF1A	0.461582734	0.39082512	0.36479129	58	4	0.015266762	FALSE	22.64583333	ASF1A	ASF1A	224.8793103	23.12765957	0	58	0	0.74021848	FALSE	0	ASF1A	107970	Infinity	0.07979876
			636.2395341														0.493083308			96		0.014175523		13.7826087			146.489899